title: Enantioselective Amine-Catalyzed [4 + 2] Annulations of Allene Ketones and 2,3-Dioxopyrrolidine Derivatives: Synthesis of 4H-Pyran Derivatives.
abstract: An efficient cinchona alkaloid-derived amine catalyzed asymmetric [4 + 2] cycloaddition is successfully developed. 4H-Pyran fused pyrrolin-2-one products are readily obtained in moderate to high yields with good enantioselectivites by employing allene ketones and 2,3-dioxopyrrolidine derivatives as substrates.
authors.affiliation: †State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Zhang
authors.affiliation: †State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China.
authors.forename: Yong-Chun
authors.initials: YC
authors.lastname: Luo
authors.affiliation: †State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China.
authors.forename: Xiu-Qin
authors.initials: XQ
authors.lastname: Hu
authors.affiliation: ‡College of Mechanics and Materials, Hohai University, Nanjing 210098, P. R. China.
authors.forename: Zhu-Yin
authors.initials: ZY
authors.lastname: Wang
authors.affiliation: †State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China.
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
authors.affiliation: †State Key Laboratory of Applied Organic Chemistry, and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China.
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Xu
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D061565:Cycloaddition Reaction; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry; D011759:Pyrrolidines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000466:Alkadienes; D000588:Amines; D007659:Ketones; D011714:Pyrans; D011759:Pyrrolidines