title: Forced Aerobic Exercise Enhances Motor Recovery After Stroke: A Case Report.
abstract: OBJECTIVE
  Previously, we demonstrated that forced aerobic exercise (FE) increases the pattern of neural activation in Parkinson's disease. We sought to evaluate whether FE, when coupled with repetitive task practice, could promote motor recovery poststroke.
  
  
  METHODS
  A 46-yr-old man with ischemic stroke exhibited chronic residual upper-extremity deficits, scoring 35/66 on the Fugl-Meyer Assessment (FMA) at baseline. He completed 24 training sessions comprising 45 min of FE on a motorized stationary bicycle followed by 45 min of upper-extremity repetitive task practice.
  
  
  RESULTS
  From baseline to end of treatment, the FMA score improved by 20 points, perceived level of recovery on the Stroke Impact Scale increased by 20 percentage points, and cardiovascular function measured by peak oxygen uptake improved 30%. These improvements persisted 4 wk after the intervention ceased.
  
  
  CONCLUSIONS
  FE may be a safe and feasible rehabilitation approach to augment recovery of motor and nonmotor function while improving aerobic fitness in people with chronic stroke.
authors.affiliation: Susan M. Linder, PT, DPT, NCS, is Research Scientist, Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH; linders@ccf.org.
authors.forename: Susan M
authors.initials: SM
authors.lastname: Linder
authors.affiliation: Anson B. Rosenfeldt, PT, DPT, MBA, is Senior Physical Therapist, Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH.
authors.forename: Anson B
authors.initials: AB
authors.lastname: Rosenfeldt
authors.affiliation: Matthew Rasanow is Research Assistant, Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH.
authors.forename: Matthew
authors.initials: M
authors.lastname: Rasanow
authors.affiliation: Jay L. Alberts, PhD, is Staff, Department of Biomedical Engineering, Cleveland Clinic, and Investigator, Cleveland FES Center, L. Stokes Cleveland VA Medical Center, Cleveland, OH.
authors.forename: Jay L
authors.initials: JL
authors.lastname: Alberts
mesh_terms: D015444:Exercise; D005081:Exercise Therapy / Q000379:methods*; D006801:Humans; D020243:Infarction, Anterior Cerebral Artery / Q000150:complications / Q000503:physiopathology / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D009068:Movement; D010291:Paresis / Q000209:etiology / Q000503:physiopathology / Q000534:rehabilitation*; D020127:Recovery of Function; D016896:Treatment Outcome