title: Brief Note Low diversity of the major histocompatibility complex class II DRA gene in domestic goats (Capra hircus) in Southern China.
abstract: DRA encodes the alpha chain of the DR heterodimer, is closely linked to DRB and is considered almost monomorphic in major histocompatibility complex region. In this study, we identified the exon 2 of DRA to evaluate the immunogenetic diversity of Chinese south indigenous goat. Two single nucleotide polymorphisms in an untranslated region and one synonymous substitution in coding region were identified. These data suggest that high immunodiversity in native Chinese population.
authors.affiliation: College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivores, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, China.
authors.forename: L P
authors.initials: LP
authors.lastname: Chen
authors.affiliation: College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivores, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, China.
authors.forename: G X
authors.initials: GX
authors.lastname: E
authors.affiliation: College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivores, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, China.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Zhao
authors.affiliation: College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivores, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, China.
authors.forename: R S
authors.initials: RS
authors.lastname: Na
authors.affiliation: College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivores, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, China.
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Zhao
authors.affiliation: College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivores, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, China.
authors.forename: J H
authors.initials: JH
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Farm Animal Genetic Resources and Utilization of Ministry of Agriculture, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
authors.forename: Y H
authors.initials: YH
authors.lastname: Ma
authors.affiliation: College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivores, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, China.
authors.forename: Y W
authors.initials: YW
authors.lastname: Sun
authors.affiliation: Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan, China.
authors.forename: T
authors.initials: T
authors.lastname: Zhong
authors.affiliation: Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan, China.
authors.forename: H P
authors.initials: HP
authors.lastname: Zhang
authors.affiliation: College of Animal Science and Technology, Chongqing Key Laboratory of Forage and Herbivores, Chongqing Engineering Research Centre for Herbivores Resource Protection and Utilization, Southwest University, Chongqing, China H67738337@swu.edu.cn.
authors.forename: Y F
authors.initials: YF
authors.lastname: Huang
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D002681:China; D005091:Exons; D006041:Goats / Q000145:classification / Q000235:genetics* / Q000276:immunology; D059805:HLA-DR alpha-Chains / Q000235:genetics* / Q000276:immunology; D007438:Introns; D016366:Open Reading Frames; D011110:Polymorphism, Genetic; D020506:Untranslated Regions
chemical_list: D059805:HLA-DR alpha-Chains; D020506:Untranslated Regions