title: Hot Topics in Noninvasive Ventilation: Report of a Working Group at the International Symposium on Sleep-Disordered Breathing in Leuven, Belgium.
abstract: During the last few decades, attention has increasingly focused on noninvasive ventilation (NIV) in the treatment of chronic respiratory failure. The University of Leuven and the University Hospitals Leuven therefore chose this topic for a 2-day working group session during their International Symposium on Sleep-Disordered Breathing. Numerous European experts took part in this session and discussed (1) NIV in amyotrophic lateral sclerosis (when to start NIV, NIV and sleep, secretion management, and what to do when NIV fails), (2) recent insights in NIV and COPD (high-intensity NIV, NIV in addition to exercise training, and NIV during exercise training), (3) monitoring of NIV (monitoring devices, built-in ventilator software, leaks, and asynchronies) and identifying events during NIV; and (4) recent and future developments in NIV (target-volume NIV, electromyography-triggered NIV, and autoregulating algorithms).
authors.affiliation: Department of Respiratory Diseases, University Hospitals Leuven, Katholieke Universiteit Leuven/University of Leuven, Leuven, Belgium.
authors.forename: Bart
authors.initials: B
authors.lastname: Vrijsen
authors.affiliation: Sleep and Ventilation Unit, Royal Brompton Hospital, London, United Kingdom.
authors.forename: Michelle
authors.initials: M
authors.lastname: Chatwin
authors.affiliation: Division of Pulmonary Diseases, Geneva University Hospitals, Geneva, Switzerland.
authors.forename: Oliver
authors.initials: O
authors.lastname: Contal
authors.affiliation: Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
authors.forename: Eric
authors.initials: E
authors.lastname: Derom
authors.affiliation: Division of Pulmonary Diseases, Geneva University Hospitals, Geneva, Switzerland.
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Janssens
authors.affiliation: Home Ventilation Service, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: Mike J
authors.initials: MJ
authors.lastname: Kampelmacher
authors.affiliation: Service de Pneumologie et Unité de Soins Intensifs Respiratoires, Centre Hospitalier Universitaire de Rouen, Rouen, France.
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Muir
authors.affiliation: Faculty of Medicine, Institute of Molecular Medicine, and Translational Clinical Physiology Unit, University of Lisbon, Lisbon, Portugal.
authors.forename: Susana
authors.initials: S
authors.lastname: Pinto
authors.affiliation: Pneumologie et Réanimation Respiratoire, Centre Hospitalier Universitaire de Dijon, Dijon, France.
authors.forename: Claudio
authors.initials: C
authors.lastname: Rabec
authors.affiliation: Division of Asthma, Allergy and Lung Biology, King's College London, London, United Kingdom.
authors.forename: Michelle
authors.initials: M
authors.lastname: Ramsay
authors.affiliation: Institut für Pneumologie an der Universität Witten/Herdecke, Klinik für Pneumologie und Allergologie, and Zentrum für Schlaf- und Beatmungsmedizin, Krankenhaus Bethanien, Solingen, Germany.
authors.forename: Winfried J
authors.initials: WJ
authors.lastname: Randerath
authors.affiliation: Kliniken der Stadt Köln gGmbH, Witten/Herdecke University Hospital, and Department of Pneumology, Cologne-Merheim Hospital, Cologne, Germany.
authors.forename: Jan H
authors.initials: JH
authors.lastname: Storre
authors.affiliation: Center for Home Mechanical Ventilation, University of Groningen, and Department of Pulmonology, Groningen University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Wijkstra
authors.affiliation: Kliniken der Stadt Köln gGmbH, Witten/Herdecke University Hospital, and Department of Pneumology, Cologne-Merheim Hospital, Cologne, Germany.
authors.forename: Wolfram
authors.initials: W
authors.lastname: Windisch
authors.affiliation: Department of Respiratory Diseases, University Hospitals Leuven, Katholieke Universiteit Leuven/University of Leuven, Leuven, Belgium. dries.testelmans@uzleuven.be.
authors.forename: Dries
authors.initials: D
authors.lastname: Testelmans
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000628:therapy*; D001530:Belgium; D005060:Europe; D006801:Humans; D063087:Noninvasive Ventilation / Q000379:methods / Q000639:trends*; D029424:Pulmonary Disease, Chronic Obstructive / Q000628:therapy*; D012131:Respiratory Insufficiency / Q000628:therapy*; D012891:Sleep Apnea Syndromes / Q000628:therapy*
keywords: amyotrophic lateral sclerosis; chronic obstructive pulmonary disease; exercise training; noninvasive ventilation; sleep; sleep monitoring