title: Immune Response in Hepatitis B Virus Infection.
abstract: Hepatitis B virus (HBV) can replicate within hepatocytes without causing direct cell damage. The host immune response is, therefore, not only essential to control the spread of virus infection, but it is also responsible for the inflammatory events causing liver pathologies. In this review, we discuss how HBV deals with host immunity and how we can harness it to achieve virus control and suppress liver damage.
authors.affiliation: Program Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore 169857.
authors.forename: Anthony
authors.initials: A
authors.lastname: Tan
authors.affiliation: Viral Hepatitis Laboratory, Singapore Institute for Clinical Sciences, A*STAR, Singapore 117609.
authors.forename: Sarene
authors.initials: S
authors.lastname: Koh
authors.affiliation: Program Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore 169857 Viral Hepatitis Laboratory, Singapore Institute for Clinical Sciences, A*STAR, Singapore 117609 School of Immunity and Infection, College of Medical and Dental Science, University of Birmingham, Edgbaston, Birmingham B16 2TT, United Kingdom.
authors.forename: Antonio
authors.initials: A
authors.lastname: Bertoletti
mesh_terms: D056704:Adaptive Immunity / Q000502:physiology; D005260:Female; D006509:Hepatitis B / Q000276:immunology* / Q000821:virology; D006515:Hepatitis B virus / Q000276:immunology*; D019694:Hepatitis B, Chronic / Q000276:immunology / Q000821:virology; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D007113:Immunity, Innate / Q000276:immunology*; D008297:Male; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index