title: Disseminated infection caused by Emmonsia pasteuriana in a renal transplant recipient.
abstract: Emmonsia pasteuriana is a thermally dimorphic fungus identified in very few human cases. Here, we report a case of a 43-year-old male renal transplant patient from China presenting with multiple painful skin eruptions on his head, nose and left thigh, later accompanied by respiratory failure. Histopathology of the biopsy collected from the left thigh upper ulcer and occipital nodule both demonstrated chronic inflammation with granuloma formation and yeast-like elements. Emmonsia pasteuriana was cultured from two biopsy specimens and their identity was confirmed by sequencing of the rDNA internal transcribed spacer. The patient in intensive care showed marked clinical improvement with antifungal treatment.
authors.affiliation: Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Peiying
authors.initials: P
authors.lastname: Feng
authors.affiliation: Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Songchao
authors.initials: S
authors.lastname: Yin
authors.affiliation: Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Guoxing
authors.initials: G
authors.lastname: Zhu
authors.affiliation: Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Meirong
authors.initials: M
authors.lastname: Li
authors.affiliation: Division of Pulmonary and Critical Care, Department of Internal Medicine, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Benquan
authors.initials: B
authors.lastname: Wu
authors.affiliation: Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Xie
authors.affiliation: Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Han
authors.initials: H
authors.lastname: Ma
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Cailian
authors.initials: C
authors.lastname: Cheng
authors.affiliation: CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands.|Institute for Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam, The Netherlands.|Peking University Health Science Center, Research Center for Medical Mycology, Beijing, China.|Shanghai Institute of Medical Mycology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Gerrit Sijbrand
authors.initials: GS
authors.lastname: de Hoog
authors.affiliation: Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Lu
authors.affiliation: Department of Dermatology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Lai
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D002681:China; D002912:Chrysosporium / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D003881:Dermatomycoses / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D012131:Respiratory Insufficiency / Q000209:etiology
chemical_list: D000935:Antifungal Agents
keywords: Emmonsia pasteuriana; cutaneous infection; dimorphic fungus; internal transcribed spacer rDNA; respiratory failure