title: PP058. Cradle: Community blood pressure monitoring in rural Africa: Detection of underlying pre-eclampsia.
abstract: BACKGROUND
  In many developing countries pre-eclampsia is under-detected partly due to inadequate training in accurate blood pressure (BP) measurements and insufficient, poorly functioning equipment.
  
  
  OBJECTIVE
  To evaluate whether the introduction of easy to use, low cost novel BP devices (Microlife 3AS1-2; designed by our research group specifically for use in developing countries and validated in pregnancy (B/A grade) according to BHS criteria) into rural clinics in Tanzania, Zimbabwe and Zambia increases referrals for suspected pre-eclampsia to a central referral hospital (as reflected by an increase in mean BP in pregnant women seen in the central referral site).
  
  
  METHODS
  International prospective longitudinal pre- and post-intervention pilot study. BP measurements were taken from consecutive women ⩾20 weeks' gestation who accessed care at a referral site (N=694). 20 BP devices were distributed to 20 rural antenatal clinics in each country. Post-intervention data was collected the following year (N=547).
  
  
  RESULTS
  After adjustment for confounders, there was a significant increase in primary outcome; post-intervention mean diastolic BP for all women (2.39mmHg, p<0.001, 95% CI 0.97-3.8), implying an increased proportion of referred hypertensive women; and a reduction in proportion of women (median gestation 35 weeks') who had never previously had a BP taken in pregnancy (25.1% to 16.9%, OR 0.58, p=0.001, CI 0.42-0.79).
  
  
  CONCLUSIONS
  Equipping community healthcare providers with this novel validated BP device is feasible, widely accepted and results in increased referrals for suspected pre-eclampsia. A cluster RCT to evaluate the effect of these monitors equipped with a traffic-light 'early warning system' is planned.
authors.forename: Natasha
authors.initials: N
authors.lastname: Hezelgrave
authors.forename: Annemarie
authors.initials: A
authors.lastname: de Greef
authors.forename: Lucy
authors.initials: L
authors.lastname: Irvine
authors.forename: Paul
authors.initials: P
authors.lastname: Seed
authors.forename: Samara
authors.initials: S
authors.lastname: Radford
authors.forename: Andrew
authors.initials: A
authors.lastname: Shennan