title: Percutaneous CT-Guided Cryoablation as an Alternative Treatment for an Extensive Pelvic Bone Giant Cell Tumor.
abstract: A giant cell tumor (GCT) is an intermediate grade, locally aggressive neoplasia. Despite advances in surgical and clinical treatments, cases located on the spine and pelvic bones remain a significant challenge. Failure of clinical treatment with denosumab and patient refusal of surgical procedures (hemipelvectomy) led to the use of cryoablation. We report the use of percutaneous CT-guided cryoablation as an alternative treatment, shown to be a minimally invasive, safe, and effective option for a GCT with extensive involvement of the pelvic bones and allowed structural and functional preservation of the involved bones.
authors.affiliation: Radiology and Imaged Guided Intervention Service, Sírio Libânes Hospital, 91, Adma Jafet Street, São Paulo, SP, 01308-050, Brazil.
authors.forename: Pedro Sergio Brito
authors.initials: PS
authors.lastname: Panizza
authors.affiliation: Radiology and Imaged Guided Intervention Service, Sírio Libânes Hospital, 91, Adma Jafet Street, São Paulo, SP, 01308-050, Brazil.
authors.forename: Conrado Furtado
authors.initials: CF
authors.lastname: de Albuquerque Cavalcanti
authors.affiliation: Instituto Avanços em Medicina, 190, Barata Ribeiro Street, São Paulo, SP, 01308-000, Brazil.
authors.forename: Nise Hitomi
authors.initials: NH
authors.lastname: Yamaguchi
authors.affiliation: Radiology and Imaged Guided Intervention Service, Sírio Libânes Hospital, 91, Adma Jafet Street, São Paulo, SP, 01308-050, Brazil.
authors.forename: Claudia Costa
authors.initials: CC
authors.lastname: Leite
authors.affiliation: Radiology and Imaged Guided Intervention Service, Sírio Libânes Hospital, 91, Adma Jafet Street, São Paulo, SP, 01308-050, Brazil.
authors.forename: Giovanni Guido
authors.initials: GG
authors.lastname: Cerri
authors.affiliation: Radiology and Imaged Guided Intervention Service, Sírio Libânes Hospital, 91, Adma Jafet Street, São Paulo, SP, 01308-050, Brazil. marcos.menezes@hc.fm.usp.br.
authors.forename: Marcos Roberto
authors.initials: MR
authors.lastname: de Menezes
mesh_terms: D001706:Biopsy; D001859:Bone Neoplasms / Q000473:pathology* / Q000601:surgery*; D003452:Cryosurgery / Q000379:methods*; D005870:Giant Cell Tumors / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010384:Pelvic Bones / Q000473:pathology*; D015641:Radiography, Interventional; D014057:Tomography, X-Ray Computed
keywords: Bone giant cell tumor; CT guided; Cryoablation; Pelvic bone tumor