title: The End of the International Reference Pricing System?
abstract: All 28 EU member states except Sweden and the UK apply international reference pricing (IRP), international price comparison, external reference pricing or cross-reference pricing. The attractiveness of using prices of other countries as a benchmark for decisions within a national price control is obvious. Alternative models for price and reimbursement decision making such as value-based pricing (VBP), i.e. cost-effectiveness analyses, are more complicated. However, IRP provides incentives for stakeholders to take action not in line with optimal (welfare-maximizing) pricing. IRP is costly for two reasons. First, manufacturers are incentivised to limit or delay access to new innovative treatments in countries with small markets and/or a low income, which can be costly in terms of loss of health. Second, all countries also experience a loss of welfare (health) because IRP reduces the opportunities for differential pricing (Ramsey pricing), i.e. using the fact that the ability and willingness to pay differs between countries. Thus, IRP results in less sales revenue to finance research and development of new innovative drugs. We can now observe that payers and manufacturers are engaged in different types of risk-sharing schemes, price-volume negotiations, payback arrangements, confidential discounts, coverage with evidence developments, etc., all with the purpose of returning to the old model of price discrimination and Ramsey pricing. Shortly, real prices for use in IRP systems will cease to exist and, thus, we expect to soon see the end of IRP, a new system for price discrimination and an increasing demand for VBP.
authors.affiliation: The Swedish Institute for Health Economics (IHE), Box 2127, SE-22002, Lund, Sweden. ulf.persson@ihe.se.|School of Economics and Management, Lund University, Lund, Sweden. ulf.persson@ihe.se.
authors.forename: Ulf
authors.initials: U
authors.lastname: Persson
authors.affiliation: Stockholm School of Economics, Stockholm, Sweden.
authors.forename: Bengt
authors.initials: B
authors.lastname: Jönsson
mesh_terms: D003363:Cost Control / Q000379:methods*; D005062:European Union; D017048:Health Care Costs; D006801:Humans; D007391:International Cooperation; D062505:Value-Based Purchasing