title: Therapeutic management of evans syndrome in a pregnancy with maternal systemic lupus erythematosus.
abstract: A 31-year-old 2 G 1 P was referred to our unit of prenatal medicine at 35+3 weeks of gestation with a spontaneously conceived singleton pregnancy of a female fetus without detectable anomalies. Maternal hematological evaluation revealed an Evans-syndrome-related thrombocytopenia based on a lupus erythematosus. The former delivery was aggravated by a severe hemorrhage several years before. Anti-autoimmunologic therapy was started and maternal platelets count increased to physiological values. Uneventful ceasarean section was performed at 37 weeks of gestation with favourable outcome for mother and child. This case is the first report of a successful therapy in maternal Evans syndrome in pregnancy combined with a lupus erythematosus.
authors.affiliation: Department of Gynecology and Obstetrics, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: S L
authors.initials: SL
authors.lastname: Nause
authors.affiliation: Department of Pediatrics and Neonatology, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Spiegler
authors.affiliation: Department of Gynecology and Obstetrics, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Weichert
authors.affiliation: Department of Gynecology and Obstetrics, University Hospital Schleswig-Holstein, Luebeck, Germany.
authors.forename: D R
authors.initials: DR
authors.lastname: Hartge
mesh_terms: D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000628:therapy*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002585:Cesarean Section / Q000379:methods*; D005260:Female; D006801:Humans; D050498:Live Birth; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000628:therapy*; D011239:Prednisolone / Q000627:therapeutic use*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000628:therapy*; D013921:Thrombocytopenia / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone