title: [Efficacy of baclosan in combined therapy of muscular-tonic pain syndrome in the early postoperative period in patients after microdiscectomy].
abstract: OBJECTIVE
  A comparative analysis of the efficacy of baclosan in adjuvant therapy of muscular-tonic pain syndromes in the early postoperative period after microdiscectomy.
  
  
  METHODS
  One hundred and three patients (65 men and 38 women, mean age 42±5,0 years) were divided into two sex- and age-matched groups depending on the treatment. Patients of group 1 received baclosan in the combination with standard therapy, patients of group 2 received standard therapy. Patients were assessed before treatment, at 3 and 10 days of treatment.
  
  
  CONCLUSIONS
  Treatment effect (maximum relief of pain and anxiety-depressive syndromes) was achieved earlier in group 1 compared to group 2. The questions of substantiation of pathogenetic action of baclosan effect in the complex therapy of muscular-tonic pain syndromes in patients after microdiscectomy are considered.
authors.affiliation: Polyclinic #11, Irkutsk.
authors.forename: S V
authors.initials: SV
authors.lastname: Kryuchkova
mesh_terms: D000328:Adult; D001418:Baclofen / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D017586:Diskectomy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*; D059352:Musculoskeletal Pain / Q000188:drug therapy* / Q000209:etiology*; D010149:Postoperative Pain / Q000188:drug therapy* / Q000209:etiology*; D011184:Postoperative Period; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen