title: Hypertrophic olivary degeneration resulting from posterior fossa masses and their treatments.
abstract: OBJECTIVE
  Characterize hypertrophic olivary degeneration (HOD) that develops from posterior fossa masses and their treatments.
  
  
  METHODS
  Retrospectively reviewed MR images and clinical data of 10 patients with posterior fossa masses and HOD.
  
  
  RESULTS
  Eight patients had cerebellar lesions, and two patients had pontine lesions. Lesions consisted of tumors, demyelination, and nonspecific necrosis. MRI showed T2 hyperintense signal in the inferior olive a median 86 days after the diagnosis of a posterior fossa lesion. HOD presented prior to surgery (n=2), after surgery (n=3), after surgery/radiation therapy (n=4), or without treatment (n=1).
  
  
  CONCLUSIONS
  HOD may develop from posterior fossa masses and surgical and/or radiation therapy.
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: mikihirano89@gmail.com.
authors.forename: Miki
authors.initials: M
authors.lastname: Hirano
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: hatzoglv@mskcc.org.
authors.forename: Vaios
authors.initials: V
authors.lastname: Hatzoglou
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: karimis@mskcc.org.
authors.forename: Sasan
authors.initials: S
authors.lastname: Karimi
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: youngr@mskcc.org.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Young
mesh_terms: D000328:Adult; D000368:Aged; D002675:Child, Preschool; D003711:Demyelinating Diseases / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000209:etiology / Q000473:pathology; D015192:Infratentorial Neoplasms / Q000473:pathology* / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009847:Olivary Nucleus / Q000473:pathology* / Q000528:radiation effects / Q000601:surgery; D011183:Postoperative Complications / Q000473:pathology; D011881:Radiotherapy, Computer-Assisted / Q000009:adverse effects*; D012189:Retrospective Studies; D013514:Surgical Procedures, Operative / Q000009:adverse effects*
keywords: All oncology; MRI; Radiation-therapy tumor; Surgical-therapy tumor