title: N-Heterocyclic carbene-catalyzed [3+3] cyclocondensation of bromoenals with aldimines: highly enantioselective synthesis of dihydropyridinones.
abstract: The N-heterocyclic carbene-catalyzed [3+3] cyclocondensation of bromoenals and aldimines was developed to give the corresponding dihydropyridinones in good yields with excellent enantioselectivities.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. songye@iccas.ac.cn.
authors.forename: Zhong-Hua
authors.initials: ZH
authors.lastname: Gao
authors.forename: Xiang-Yu
authors.initials: XY
authors.lastname: Chen
authors.forename: Han-Ming
authors.initials: HM
authors.lastname: Zhang
authors.forename: Song
authors.initials: S
authors.lastname: Ye
mesh_terms: D001966:Bromine / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D061565:Cycloaddition Reaction; D007097:Imines / Q000138:chemical synthesis / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008958:Models, Molecular; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: C000599809:1,2-dihydropyridinone; D007097:Imines; D011728:Pyridones; C030011:carbene; D008697:Methane; D001966:Bromine