title: Diagnostic Value of Different Systematic Prostate Biopsy Methods in the Detection of Prostate Cancer with Ultrasonographic Hypoechoic Lesions--A Comparative Study.
abstract: OBJECTIVE
  To assess if a less extended biopsy in the transperineal approach is sufficient for detection of prostate cancer (PC) in patients with hypoechoic lesions.
  
  
  METHODS
  This was a prospective study of 167 consecutive patients with prostate hypoechoic lesion and who underwent transperineal ultrasound (TPUS)-guided 12-core and hypoechoic lesion core biopsy between January 2012 and February 2013.
  
  
  RESULTS
  PC was detected in 64.1% (107/167) of patients. The PC detection rate of the 12-core prostate biopsy scheme was the highest, but when including the hypoechoic lesion core, there was no difference between the 6- and 12-core schemes (all p > 0.05), irrespective of prostate volume or prostate-specific antigen levels (all p > 0.05).
  
  
  CONCLUSIONS
  A more limited biopsy scheme could be sufficient for the detection of PC if the hypoechoic lesion is sampled.
authors.affiliation: Department of Medical Ultrasound, Shanghai Tenth People's Hospital, Tenth People's Hospital of Tongji University, Shanghai, China.
authors.forename: Guang
authors.initials: G
authors.lastname: Xu
authors.forename: Minghua
authors.initials: M
authors.lastname: Yao
authors.forename: Jian
authors.initials: J
authors.lastname: Wu
authors.forename: Lehang
authors.initials: L
authors.lastname: Guo
authors.forename: Lijing
authors.initials: L
authors.lastname: Feng
authors.forename: Shuai
authors.initials: S
authors.lastname: Wang
authors.forename: Lixia
authors.initials: L
authors.lastname: Zhao
authors.forename: Huixiong
authors.initials: H
authors.lastname: Xu
authors.forename: Rong
authors.initials: R
authors.lastname: Wu
mesh_terms: D000368:Aged; D062005:Biopsy, Large-Core Needle / Q000379:methods*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D014463:Ultrasonography
chemical_list: D017430:Prostate-Specific Antigen