title: Identification of a Novel ALK G1123S Mutation in a Patient with ALK-rearranged Non-small-cell Lung Cancer Exhibiting Resistance to Ceritinib.
authors.affiliation: Department of Thoracic Oncology, National Kyushu Cancer Center, Minami-ku, Fukuoka, Japan.
authors.forename: Gouji
authors.initials: G
authors.lastname: Toyokawa
authors.forename: Eiko
authors.initials: E
authors.lastname: Inamasu
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Shimamatsu
authors.forename: Tsukihisa
authors.initials: T
authors.lastname: Yoshida
authors.forename: Kaname
authors.initials: K
authors.lastname: Nosaki
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Hirai
authors.forename: Masafumi
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: Takashi
authors.initials: T
authors.lastname: Seto
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Takenoyama
authors.forename: Yukito
authors.initials: Y
authors.lastname: Ichinose
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000201:enzymology* / Q000235:genetics; D019008:Drug Resistance, Neoplasm; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000201:enzymology* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011743:Pyrimidines / Q000627:therapeutic use*; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics*; D013450:Sulfones / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D011743:Pyrimidines; D013450:Sulfones; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases; C586847:ceritinib