title: Invasive versus non-invasive monitoring of acute severe hypertension in women with pre-eclampsia.
abstract: OBJECTIVE
  To compare the accuracy of two non-invasive methods of blood-pressure measurement with intra-arterial measurement in women with pre-eclampsia and acute severe hypertension.
  
  
  METHODS
  This descriptive, cross-sectional study prospectively enrolled 23 women with pre-eclampsia and acute severe hypertension for continuous intra-arterial blood-pressure monitoring. Simultaneous monitoring was performed with a manual and an automated, non-invasive device during episodes of severe hypertension. The paired T-test was used to compare measured values. The accuracy of a MAP⩾125mmHg in detecting a systolic blood pressure⩾160mmHg was determined.
  
  
  RESULTS
  There was a weak correlation between intra-arterial and automated as well as intra-arterial and manual systolic values (r=0.34, p<0.01; r=0.41, p<0.00, respectively). Better correlation was found amongst diastolic values. The differences between the mean intra-arterial (94±11mmHg) and automated (96±12mmHg) diastolic values as well as intra-arterial and manual diastolic measurements (94±14mmHg) were not significant (p=0.20, 0.65, respectively). A mean arterial pressure⩾125mmHg was not accurate in detecting a systolic value⩾160mmHg, with low sensitivities (17.2-35.9%) and specificities (0-50%) for all three methods.
  
  
  CONCLUSIONS
  When compared to intra-arterial monitoring, the automated and manual methods showed weak correlation with systolic but better correlation with diastolic values. A mean arterial pressure⩾125mmHg was not accurate in detecting systolic peaks. When protection against cerebral haemorrhage is paramount, intra-arterial measurement of systolic values is best.
authors.affiliation: Department of Obstetrics and Gynaecology, Stellenbosch University and Tygerberg Academic Hospital, South Africa. Electronic address: langen@sun.ac.za.
authors.forename: E
authors.initials: E
authors.lastname: Langenegger
authors.affiliation: Department of Obstetrics and Gynaecology, Stellenbosch University and Tygerberg Academic Hospital, South Africa.
authors.forename: S
authors.initials: S
authors.lastname: Dalla
authors.affiliation: Department of Obstetrics and Gynaecology, Stellenbosch University and Tygerberg Academic Hospital, South Africa.
authors.forename: G
authors.initials: G
authors.lastname: Petro
authors.affiliation: Department of Obstetrics and Gynaecology, Stellenbosch University and Tygerberg Academic Hospital, South Africa.
authors.forename: D
authors.initials: D
authors.lastname: Hall
keywords: Blood pressure; Monitoring; Pre-eclampsia; Severe hypertension