title: [Bone and Nutrition. Functional foods for bone and cartilage tissues : Evidence for the action of collagen peptides].
abstract: Collagen peptides, including glucosamine, are well-known functional food materials that act on bone and cartilage tissues. Collagen peptides are used at a volume of about 6,000 tons per year as a raw material in Japan. Evidence for the action of collagen peptides for both bone and cartilage tissues has accumulated both at basic research level (in vivo and in vitro ) and clinically. To confirm the clinical effect of these peptides and clearly identify their mechanism of action at the molecular level, further clinical studies comprising disease-free subjects, alongside basic research studies, are required.
authors.affiliation: Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Sciences, Josai University, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Kimira
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mano
mesh_terms: D000818:Animals; D015519:Bone Density / Q000187:drug effects; D001842:Bone and Bones / Q000166:cytology / Q000378:metabolism*; D002356:Cartilage / Q000166:cytology / Q000378:metabolism*; D002454:Cell Differentiation / Q000187:drug effects / Q000235:genetics; D049109:Cell Proliferation / Q000187:drug effects / Q000235:genetics; D019902:Chondrocytes / Q000166:cytology; D003094:Collagen / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D055951:Functional Food; D018507:Gene Expression Regulation, Developmental / Q000187:drug effects; D006801:Humans; D006909:Hydroxyproline; D010006:Osteoblasts / Q000166:cytology; D010024:Osteoporosis / Q000378:metabolism / Q000517:prevention & control; D010446:Peptide Fragments / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D011392:Proline; D051381:Rats
chemical_list: D010446:Peptide Fragments; D003094:Collagen; D011392:Proline; D006909:Hydroxyproline