title: Frequency analysis of a self-bending point spread function for 3D localization-based optical microscopy.
abstract: We developed several approaches to characterize the recently reported self-bending point spread function for 3D localization-based light microscopy. Experimentally, we generated Gaussian, astigmatic, and self-bending point spread functions. We compared the optical transfer functions, ambiguity functions, and Fisher information of these point spread functions. Our comprehensive frequency-domain analysis describes quantitative tools for the development of engineered point spread functions for 3D imaging systems.
authors.forename: Bryce
authors.initials: B
authors.lastname: Schroeder
authors.forename: Shu
authors.initials: S
authors.lastname: Jia
mesh_terms: D021621:Imaging, Three-Dimensional / Q000379:methods*; D008853:Microscopy / Q000379:methods*; D016011:Normal Distribution