title: A renin-ssance in primary aldosteronism testing: obstacles and opportunities for screening, diagnosis, and management.
authors.affiliation: Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada;
authors.forename: Joshua E
authors.initials: JE
authors.lastname: Raizman
authors.affiliation: Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Clinical Biochemistry, University Health Network, Toronto, Ontario, Canada; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada; ediamandis@mtsinai.on.ca.
authors.forename: Eleftherios P
authors.initials: EP
authors.lastname: Diamandis
authors.affiliation: Clinical Associate Professor, Department of Pathology and Laboratory Medicine and Head, Clinical Chemistry, St. Paul's Hospital, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Canada;
authors.forename: Daniel
authors.initials: D
authors.lastname: Holmes
authors.affiliation: Professor, Endocrine Hypertension Research Centre, University of Queensland School of Medicine, Australia;
authors.forename: Michael
authors.initials: M
authors.lastname: Stowasser
authors.affiliation: Professor of Internal Medicine and Director, Fellowship Program, Division of Metabolism, Endocrinology & Diabetes, Department of Internal Medicine University of Michigan Medical School, Ann Arbor, MI;
authors.forename: Richard
authors.initials: R
authors.lastname: Auchus
authors.affiliation: Professor and Head, Department of Clinical Chemistry, University of Liège, Liège, Belgium.
authors.forename: Etienne
authors.initials: E
authors.lastname: Cavalier
mesh_terms: D000450:Aldosterone / Q000097:blood*; D020746:Calcium Channels, L-Type / Q000235:genetics; D005438:Fludrocortisone; D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels / Q000235:genetics; D006801:Humans; D006929:Hyperaldosteronism / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D006973:Hypertension / Q000150:complications; D007118:Immunoassay / Q000379:methods / Q000592:standards; D009154:Mutation; D053499:Plasma Membrane Calcium-Transporting ATPases / Q000235:genetics; D012016:Reference Values; D012083:Renin / Q000097:blood*; D012680:Sensitivity and Specificity; D000254:Sodium-Potassium-Exchanging ATPase / Q000235:genetics
chemical_list: C472073:CACNA1D protein, human; D020746:Calcium Channels, L-Type; D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels; C484274:KCNJ5 protein, human; D000450:Aldosterone; D012083:Renin; C499076:ATP1A1 protein, human; D053499:Plasma Membrane Calcium-Transporting ATPases; C506962:ATP2B3 protein, human; D000254:Sodium-Potassium-Exchanging ATPase; D005438:Fludrocortisone