title: Rituximab-Induced Acute ST Elevation Myocardial Infarction.
abstract: BACKGROUND
  Rituximab has rarely been associated with acute coronary syndrome (ACS). We report the case of a patient in whom rituximab, a monoclonal antibody used to treat lymphomas of B-cell origin, induced ST elevation myocardial infarction.
  
  
  METHODS
  A 46-year-old male patient diagnosed with stage II non-Hodgkin lymphoma presented to the emergency department with acute crushing, substernal chest pain that radiated to his back 1 day after a chemotherapy infusion with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone. An electrocardiogram revealed normal sinus rhythm with ST elevations in the inferior leads. The patient underwent primary percutaneous coronary intervention (PCI) of his right coronary artery and first diagonal artery with placement of drug-eluting stents. He did well postprocedure and resumed therapy with rituximab under close monitoring by the cardiology and oncology departments without any further cardiac events.
  
  
  CONCLUSIONS
  In patients with ACS because of chemotherapy, complete revascularization during PCI should be considered.
authors.affiliation: The John Ochsner Heart and Vascular Institute, Ochsner Clinic Foundation, New Orleans, LA.
authors.forename: Amit N
authors.initials: AN
authors.lastname: Keswani
authors.affiliation: Department of Internal Medicine, Ochsner Clinic Foundation, New Orleans, LA.
authors.forename: Cody
authors.initials: C
authors.lastname: Williams
authors.affiliation: Department of Hematology and Oncology, Ochsner Clinic Foundation, New Orleans, LA.
authors.forename: Jyotsna
authors.initials: J
authors.lastname: Fuloria
authors.affiliation: The John Ochsner Heart and Vascular Institute, Ochsner Clinic Foundation, New Orleans, LA ; The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA.
authors.forename: Nichole M
authors.initials: NM
authors.lastname: Polin
authors.affiliation: The John Ochsner Heart and Vascular Institute, Ochsner Clinic Foundation, New Orleans, LA ; The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA.
authors.forename: Eiman
authors.initials: E
authors.lastname: Jahangir
keywords: Acute coronary syndrome; lymphoma–non-Hodgkin; myocardial infarction; percutaneous coronary intervention; rituximab