title: Plasma and salivary total antioxidant capacity in healthy controls compared with aggressive and chronic periodontitis patients.
abstract: OBJECTIVE
  To evaluate the plasma and salivary total antioxidant capacity (TAOC) in patients with generalized chronic periodontitis (CP), generalized aggressive periodontitis (AgP), and periodontally healthy controls.
  
  
  METHODS
  This cross-sectional study includes of 88 individuals seeking dental treatment at the Faculty of Dentistry, Istanbul University, Istanbul, Turkey between January 2011 and March 2012. Fifteen AgP patients were compared with 21 healthy controls (C1), while 36 CP patients were compared with 16 healthy controls (C2). Clinical periodontal measurements were recorded, and plasma and saliva samples were collected. The TAOC of the plasma and saliva samples were determined using a commercially available colorimetric kit.
  
  
  RESULTS
  The plasma TAOC of both AgP and CP patients was significantly lower for C1 and C2. The salivary TAOC of CP patients was significantly lower for C2, but there was no significant difference between AgP patients and C1.
  
  
  CONCLUSIONS
  Our results demonstrate that severe periodontitis may be associated with a lower plasma antioxidant capacity. The reduced antioxidant capacity in patients with severe periodontitis, especially with aggressive forms may be an important contributing factor to severe tissue destruction.
authors.affiliation: Department of Periodontology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey. E-mail. baserulku@hotmail.com.
authors.forename: Ulku
authors.initials: U
authors.lastname: Baser
authors.forename: Hikmet
authors.initials: H
authors.lastname: Gamsiz-Isik
authors.forename: Emine
authors.initials: E
authors.lastname: Cifcibasi
authors.forename: Evin
authors.initials: E
authors.lastname: Ademoglu
authors.forename: Funda
authors.initials: F
authors.lastname: Yalcin
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D016022:Case-Control Studies; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000097:blood / Q000378:metabolism*; D012463:Saliva / Q000378:metabolism*; D055815:Young Adult
chemical_list: D000975:Antioxidants