title: A new triterpenoid glycoside from the leaves and stems of Duranta repens.
abstract: A new triterpenoid glycoside (1) was isolated from the methanol extract of the leaves and stems of Duranta repens L. (Verbenaceae) along with 14 known compounds consisting of eight triterpenoids, four iridoids, one phenylethanoid glycoside and one flavonoid. The chemical structure of 1 was determined to be bayogenin 3-O-[β-D-glucopyranoside]-28-O-[α-L-rhamnopyranosyl-(1→5)-O-β-D-apiofuranosyl-(1→4)-O-α-L-rhamnopyranosyl-(1→2)-O-α-L-arabinopyranosyl] ester, based on spectroscopic data. In addition, the inhibitory effects of the isolates on lipoxygenase activity were examined. Among them, acteoside and apigenin resulted in 94 ± 3.6% and 82 ± 4.7% inhibition, respectively, at 0.5 mM.
authors.affiliation: a School of Agriculture, Tokai University , Minamiaso 5435, Aso, Kumamoto 869-1404 , Japan.
authors.forename: Chisato
authors.initials: C
authors.lastname: Furusawa
authors.affiliation: a School of Agriculture, Tokai University , Minamiaso 5435, Aso, Kumamoto 869-1404 , Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Yasuda
authors.affiliation: a School of Agriculture, Tokai University , Minamiaso 5435, Aso, Kumamoto 869-1404 , Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsuji
authors.affiliation: a School of Agriculture, Tokai University , Minamiaso 5435, Aso, Kumamoto 869-1404 , Japan.
authors.forename: Show
authors.initials: S
authors.lastname: Ito
authors.affiliation: b Faculty of Pharmaceutical Sciences, Sojo University , 4-22-1 Ikeda, Nishi-ku, Kumamoto 860-0082 , Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Miyashita
authors.affiliation: b Faculty of Pharmaceutical Sciences, Sojo University , 4-22-1 Ikeda, Nishi-ku, Kumamoto 860-0082 , Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Yoshimitsu
authors.affiliation: b Faculty of Pharmaceutical Sciences, Sojo University , 4-22-1 Ikeda, Nishi-ku, Kumamoto 860-0082 , Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Nohara
authors.affiliation: a School of Agriculture, Tokai University , Minamiaso 5435, Aso, Kumamoto 869-1404 , Japan.
authors.forename: Masateru
authors.initials: M
authors.lastname: Ono
mesh_terms: D002240:Carbohydrate Sequence; D005419:Flavonoids / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D029648:Verbenaceae / Q000737:chemistry*
chemical_list: D005419:Flavonoids; D006027:Glycosides; D016859:Lipoxygenase Inhibitors; D010936:Plant Extracts; D014315:Triterpenes; C000609515:bayogenin 3-O-(beta-D-glucopyranoside)-28-O-(alpha-L-rhamnopyranosyl-(1-5)-O-beta-D-apiofuranosyl-(1-4)-O-alpha-L-rhamnopyranosyl ester
keywords: Duranta repens; Vabenaceae; lipoxygenase inhibitory effect; triterpenoid glycoside