title: DNA microarray integromics analysis platform.
abstract: BACKGROUND
  The study of interactions between molecules belonging to different biochemical families (such as lipids and nucleic acids) requires specialized data analysis methods. This article describes the DNA Microarray Integromics Analysis Platform, a unique web application that focuses on computational integration and analysis of "multi-omics" data. Our tool supports a range of complex analyses, including - among others - low- and high-level analyses of DNA microarray data, integrated analysis of transcriptomics and lipidomics data and the ability to infer miRNA-mRNA interactions.
  
  
  RESULTS
  We demonstrate the characteristics and benefits of the DNA Microarray Integromics Analysis Platform using two different test cases. The first test case involves the analysis of the nutrimouse dataset, which contains measurements of the expression of genes involved in nutritional problems and the concentrations of hepatic fatty acids. The second test case involves the analysis of miRNA-mRNA interactions in polysaccharide-stimulated human dermal fibroblasts infected with porcine endogenous retroviruses.
  
  
  CONCLUSIONS
  The DNA Microarray Integromics Analysis Platform is a web-based graphical user interface for "multi-omics" data management and analysis. Its intuitive nature and wide range of available workflows make it an effective tool for molecular biology research. The platform is hosted at https://lifescience.plgrid.pl/.
authors.affiliation: Institute of Computer Science, Division of Biomedical Computer Systems, University of Silesia, Katowice, Poland ; Academic Computer Centre CYFRONET, AGH University of Science and Technology, Kraków, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Waller
authors.affiliation: Academic Computer Centre CYFRONET, AGH University of Science and Technology, Kraków, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Gubała
authors.affiliation: Molecular Biology and Clinical Genetics Laboratory, Department of Medicine, Jagiellonian University, Kraków, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Sarapata
authors.affiliation: Department of Bioinformatics and Telemedicine, Medical College, Jagiellonian University, Kraków, Poland.
authors.forename: Monika
authors.initials: M
authors.lastname: Piwowar
authors.affiliation: The Genome Analysis Centre, Norwich, UK.
authors.forename: Wiktor
authors.initials: W
authors.lastname: Jurkowski