title: Percutaneous Radiofrequency Ablation of Hepatic Metastases from Gastric Adenocarcinoma after Gastrectomy.
abstract: OBJECTIVE
  To evaluate the efficacy of percutaneous radiofrequency (RF) ablation for treatment of hepatic metastases from gastric adenocarcinoma.
  
  
  METHODS
  Of 24 patients who underwent percutaneous RF ablation after gastrectomy for a hepatic metastasis from a gastric cancer during the period 2000-2013, 19 were enrolled (median age, 63 y) with 21 metastatic tumors (mean diameter, 2.3 cm). Patient overall survival (OS) and local tumor progression-free survival (PFS) outcomes were assessed and compared according to patient and tumor characteristics, including tumor size and lobar distribution. The difference in diameter between tumor and ablation zone was compared according to lobar distribution.
  
  
  RESULTS
  The median OS after RF ablation was 20.3 months, and the median local tumor PFS was 10.4 months. The OS rate was not significantly influenced by any patient or tumor characteristics. In multivariate analysis, independent negative prognostic factors for local tumor PFS were a tumor ≥ 3 cm in diameter (hazard ratio, 10.5; 95% confidence interval, 1.8-62.5; P = .009) and a tumor located in the left lobe (hazard ratio, 9.1; 95% confidence interval, 1.3-63.5; P = .026). The difference in diameter between the tumor and ablation zone was significantly different between the right and left lobes (right 1.8 cm ± 0.6 vs left 1.1 cm ± 0.70, P = .028).
  
  
  CONCLUSIONS
  With the appropriate selection of patients with tumors ≤ 3 cm in diameter and with the possibility of sufficient safety margins, RF ablation is a safe and feasible treatment option for hepatic metastases from gastric adenocarcinoma.
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea.
authors.forename: Choong Wook
authors.initials: CW
authors.lastname: Lee
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea. Electronic address: jhkimrad@amc.seoul.kr.
authors.forename: Jin Hyoung
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea.
authors.forename: Hyung Jin
authors.initials: HJ
authors.lastname: Won
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea.
authors.forename: Yong Moon
authors.initials: YM
authors.lastname: Shin
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea.
authors.forename: Heung Kyu
authors.initials: HK
authors.lastname: Ko
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea.
authors.forename: Pyo Nyun
authors.initials: PN
authors.lastname: Kim
authors.affiliation: Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, Republic of Korea.
authors.forename: Min-Hee
authors.initials: MH
authors.lastname: Ryu
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary* / Q000628:therapy*; D000328:Adult; D000368:Aged; D017115:Catheter Ablation / Q000379:methods*; D018572:Disease-Free Survival; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome