title: Atrial fibrillation and hypertrophic cardiomyopathy: who to anticoagulate?
abstract: Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac conditions. Atrial fibrillation (AF) has been demonstrated to be the most frequent arrhythmia encountered in HCM patients. Research focusing on AF and embolic stroke in HCM patients has been sparse and the sample size of most studies is small. The prognostic significance of AF in HCM patients is still not well known. The aim of this article is to provide further understanding of the anti-coagulation requirement of HCM patients with AF.
authors.affiliation: Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Marlborough Street, Bristol, BS2 8HW, UK. a.frontera@gmail.com.
authors.forename: Antonio
authors.identifier: http://orcid.org/0000-0002-0372-4480
authors.initials: A
authors.lastname: Frontera
authors.affiliation: Department of Cardiology, University Hospitals Southampton NHS Foundation Trust, Southampton, UK.
authors.forename: D G
authors.initials: DG
authors.lastname: Wilson
authors.affiliation: Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Marlborough Street, Bristol, BS2 8HW, UK.
authors.forename: H
authors.initials: H
authors.lastname: Sekhon
authors.affiliation: Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Marlborough Street, Bristol, BS2 8HW, UK.
authors.forename: E R
authors.initials: ER
authors.lastname: Duncan
authors.affiliation: Department of Cardiology, Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Marlborough Street, Bristol, BS2 8HW, UK.
authors.forename: G
authors.initials: G
authors.lastname: Thomas
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage*; D001281:Atrial Fibrillation / Q000150:complications* / Q000188:drug therapy; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D019317:Evidence-Based Medicine; D006801:Humans; D018579:Patient Selection; D020521:Stroke / Q000209:etiology* / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants
keywords: Anticoagulation; Atrial fibrillation; Embolic stroke; Hypertrophic cardiomyopathy