title: Percutaneous Aponeurotomy and Lipofilling (PALF): A Regenerative Approach to Dupuytren Contracture.
abstract: Dupuytren disease is a progressive fibroproliferative disorder, which leads to flexion contractures of the digits. A minimally invasive technique consisting of an extensive percutaneous aponeurotomy of the cord with a needle combined with lipofilling is presented. The selective cutting of the cords under continuous tension disintegrates the cords while sparing the looser neurovascular bundles. Subsequently, lipoaspirate is injected subcutaneously. The authors' prospective results show a significantly shorter recovery time and less overall complications in this technique when compared with open surgery, while no significant difference was observed in the extent of immediate contracture correction and in the recurrence rate at 1 year follow-up.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Erasmus University Medical Center, Dr Molewaterplein 50-60, 3015 GE Rotterdam, The Netherlands. Electronic address: s.e.r.hovius@erasmusmc.nl.
authors.forename: Steven E R
authors.initials: SE
authors.lastname: Hovius
authors.affiliation: Department of Plastic and Reconstructive Surgery, Erasmus University Medical Center, Dr Molewaterplein 50-60, 3015 GE Rotterdam, The Netherlands.
authors.forename: Hester J
authors.initials: HJ
authors.lastname: Kan
authors.affiliation: Department of Plastic and Reconstructive Surgery, Erasmus University Medical Center, Dr Molewaterplein 50-60, 3015 GE Rotterdam, The Netherlands.
authors.forename: Jennifer S N
authors.initials: JS
authors.lastname: Verhoekx
authors.affiliation: Miami Hand Center, 2750 SW 37th Avenue, Miami, FL, USA.
authors.forename: Roger K
authors.initials: RK
authors.lastname: Khouri
mesh_terms: D000273:Adipose Tissue / Q000166:cytology / Q000637:transplantation*; D004387:Dupuytren Contracture / Q000503:physiopathology / Q000601:surgery*; D000071938:Fasciotomy; D006801:Humans; D009339:Needles; D012038:Regeneration; D033581:Stem Cell Transplantation; D016378:Tissue Transplantation
keywords: Dupuytren disease; Fat grafting; Lipofilling; Minimally invasive; Needle aponeurotomy; Needle fasciotomy