title: Circulating Long Noncoding RNA as a Potential Target for Prostate Cancer.
abstract: Prostate cancer is considered the second most common visceral malignancy in men in Western countries. Its emergence is largely due to the coordination of a malignant network, and long noncoding RNA has been recently demonstrated to play a critical role in prostate carcinogenesis. The aberrant expression of long noncoding RNA in prostate cancer patients is strongly associated with diagnosis, risk stratification and carcinogenesis, information that provides new insight into the complicated intracellular milieu of prostate cancer. This review focuses mainly on literature evidence for the role of long noncoding RNA in prostate cancer, which may suggest novel strategies for its prognosis, diagnosis and clinical treatment.
authors.affiliation: Trainee Brigade, the Third Military Medical University, Chongqing 400038, China. yinjiesu@tmmu.edu.cn.
authors.forename: Yin-Jie
authors.initials: YJ
authors.lastname: Su
authors.affiliation: Department of Cell Biology, the Third Military Medical University, Chongqing 400038, China. yujin100@aliyun.com.
authors.forename: Jin
authors.initials: J
authors.lastname: Yu
authors.affiliation: Department of Cell Biology, the Third Military Medical University, Chongqing 400038, China. hyq808024@163.com.
authors.forename: Ya-Qin
authors.initials: YQ
authors.lastname: Huang
authors.affiliation: Department of Cell Biology, the Third Military Medical University, Chongqing 400038, China. jinyang@tmmu.edu.cn.
authors.forename: Jin
authors.initials: J
authors.lastname: Yang
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000235:genetics*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008297:Male; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000235:genetics*; D062085:RNA, Long Noncoding / Q000037:antagonists & inhibitors* / Q000235:genetics
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D062085:RNA, Long Noncoding
keywords: biomarker; long noncoding RNA; prostate cancer; therapeutic target