title: Histiocytic Sarcoma Originating in the Lung in a 16-Year-Old Male.
abstract: We report a 16-year-old male with histiocytic sarcoma (HS) originating in the lung. Partial resection of the lung was performed for a 3-cm mass with a clear boundary detected in the right inferior pulmonary lobe on a health checkup. Histologically, the tumor infiltrated into the surrounding tissue, and was comprised of spindle cells, mainly, and foam cells accompanied by mild nuclear atypia. The tumor cells were immunohistochemically positive for CD68 and CD163, indicating histiocytic lineage and the MIB-1-positive rate was low. Spindle cell morphology of HS is quite rare and only 3 cases of pulmonary HS have previously been reported.
authors.affiliation: Department of Pathology Department of Surgery, Tokai University School of Medicine.
authors.forename: Sakura
authors.initials: S
authors.lastname: Tomita
authors.forename: Go
authors.initials: G
authors.lastname: Ogura
authors.forename: Chie
authors.initials: C
authors.lastname: Inomoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kajiwara
authors.forename: Ryota
authors.initials: R
authors.lastname: Masuda
authors.forename: Masayuki
authors.initials: M
authors.lastname: Iwazaki
authors.forename: Masaru
authors.initials: M
authors.lastname: Kojima
authors.forename: Naoya
authors.initials: N
authors.lastname: Nakamura
mesh_terms: D000293:Adolescent; D015415:Biomarkers; D054747:Histiocytic Sarcoma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D014057:Tomography, X-Ray Computed
chemical_list: D015415:Biomarkers