title: The Use of Vacuum-Assisted Closure and GranuFoam Silver® Dressing in the Management of Diabetic Foot Ulcer.
abstract: OBJECTIVE
  The aim of this retrospective study was to evaluate the efficacy of vacuum-assisted closure (VAC) and GranuFoam Silver® dressing (KCI, San Antonio, TX) compared with conventional GranuFoam® dressing in the management of diabetic foot ulcers.
  
  
  METHODS
  Twenty-one consecutive patients treated with conventional or silver-coated foam dressing were reviewed retrospectively. The wound duration was 6 mo. Group 1 (n=10) received conventional foam dressing (GranuFoam) and group 2 (n=11) received silver-coated foam dressing (GranuFoam Silver). The wound surface area, duration of treatment, bacteriology, and recurrence were compared between the groups. The mean age of the patients was 61.70±10.52 y in group 1 and 67.27±11.28 y in group 2.
  
  
  RESULTS
  In group 1, the average surface area of the wounds was 45.30±46.96 cm2 and 18.40±23.48 cm2 in the pre-treatment and post-treatment periods, respectively. There was a statistically significant difference between two measurements (p=0.005). Average duration of the treatment was 25.50±27.13 d in this group. In group 2, average surface area of the wounds in the pre-treatment and post-treatment periods were 41.55±36.03 cm2 and 7.64±3.91 cm2, respectively. There was a statistically significant difference between two measurements (p=0.003). Average duration of the treatment was 10.09±3.51 d in this group. The patients treated with silver-impregnated polyurethane foam dressing had reduced recurrence (2 vs. 7 wounds, p=0.030) and increased number of the culture-negative cases at the end of the treatment.
  
  
  CONCLUSIONS
  With the results of the study, it was concluded that VAC GranuFoam silver dressing can be superior to conventional GranuFoam dressing in reducing the recurrence rate of infected diabetic foot ulcers.
authors.affiliation: 1 Department of Infectious Diseases and Clinical Microbiolog, Gaziosmanpasa University Faculty of Medicine , Tokat, Turkey .
authors.forename: Özgür
authors.initials: Ö
authors.lastname: Günal
authors.affiliation: 2 Department of Plastic Reconstructive and Aesthetic Surgery, Gaziosmanpasa University Faculty of Medicine , Tokat, Turkey .
authors.forename: Umut
authors.initials: U
authors.lastname: Tuncel
authors.affiliation: 2 Department of Plastic Reconstructive and Aesthetic Surgery, Gaziosmanpasa University Faculty of Medicine , Tokat, Turkey .
authors.forename: Aydin
authors.initials: A
authors.lastname: Turan
authors.affiliation: 1 Department of Infectious Diseases and Clinical Microbiolog, Gaziosmanpasa University Faculty of Medicine , Tokat, Turkey .
authors.forename: Sener
authors.initials: S
authors.lastname: Barut
authors.affiliation: 2 Department of Plastic Reconstructive and Aesthetic Surgery, Gaziosmanpasa University Faculty of Medicine , Tokat, Turkey .
authors.forename: Naci
authors.initials: N
authors.lastname: Kostakoglu
mesh_terms: D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D001419:Bacteria / Q000302:isolation & purification; D001458:Bandages; D017719:Diabetic Foot / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D012008:Recurrence; D012189:Retrospective Studies; D012834:Silver / Q000008:administration & dosage*; D013995:Time; D016896:Treatment Outcome; D014456:Ulcer / Q000382:microbiology / Q000473:pathology / Q000601:surgery*
chemical_list: D000890:Anti-Infective Agents; D012834:Silver