title: Comparison of the Hemostatic Activity of Quercus persica Jaub. & Spach. (Oak) With Ferric Sulfate in Bony Crypts.
abstract: Effective tissue hemostasis in periapical surgical site is important in the procedures. Plants with large amount of tannins may act as a local hemostatic agent. We aimed to compare the hemostatic effect of the extract of Quercus persica with one of the common hemostatic material used in periapical surgery. Six standardized bone holes were prepared in the calvaria of 5 Burgundy rabbits. Two hemostatic medicaments were tested for their hemostatic effect and were compared with control defects: Group 1, cotton pellet soaked in 15.5% ferric sulfate solution; Group 2, cotton pellet soaked in pure ethanolic extract of Q. persica. Bleeding score between the groups was compared. The ferric sulfate group exhibited significantly less bleeding than the other 2 groups. Q. persica was found to cause more hemostasis than the control group at 4 and 5 minutes but there were no significant differences between normal saline and Q. persica extract in bleeding control.
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Nabavizadeh
authors.affiliation: Pharmaceutical Sciences Research Center and Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Research Office for the History of Persian Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Arman
authors.initials: A
authors.lastname: Zargaran
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Fariborz
authors.initials: F
authors.lastname: Moazami
authors.affiliation: Pharmaceutical Sciences Research Center and Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Askari
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Safoora
authors.initials: S
authors.lastname: Sahebi
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Farhadpoor
authors.affiliation: Pharmaceutical Sciences Research Center and Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Research Office for the History of Persian Medicine, Shiraz University of Medical Sciences, Shiraz, Iran faridip@sums.ac.ir.
authors.forename: Pouya
authors.initials: P
authors.lastname: Faridi
mesh_terms: D000818:Animals; D005290:Ferric Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D006470:Hemorrhage / Q000188:drug therapy* / Q000503:physiopathology; D006490:Hemostatics / Q000008:administration & dosage / Q000627:therapeutic use*; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D029963:Quercus / Q000737:chemistry*; D011817:Rabbits; D012886:Skull / Q000293:injuries*; D013634:Tannins / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D005290:Ferric Compounds; D006490:Hemostatics; D010936:Plant Extracts; D013634:Tannins; C024823:ferric sulfate
keywords: Persian medicine; Quercus persica; hemostatic activity