title: Ethylene Response Factors: A Key Regulatory Hub in Hormone and Stress Signaling.
abstract: Ethylene is essential for many developmental processes and a key mediator of biotic and abiotic stress responses in plants. The ethylene signaling and response pathway includes Ethylene Response Factors (ERFs), which belong to the transcription factor family APETALA2/ERF. It is well known that ERFs regulate molecular response to pathogen attack by binding to sequences containing AGCCGCC motifs (the GCC box), a cis-acting element. However, recent studies suggest that several ERFs also bind to dehydration-responsive elements and act as a key regulatory hub in plant responses to abiotic stresses. Here, we review some of the recent advances in our understanding of the ethylene signaling and response pathway, with emphasis on ERFs and their role in hormone cross talk and redox signaling under abiotic stresses. We conclude that ERFs act as a key regulatory hub, integrating ethylene, abscisic acid, jasmonate, and redox signaling in the plant response to a number of abiotic stresses.
authors.affiliation: Department of Plant Biology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain.
authors.forename: Maren
authors.identifier: http://orcid.org/0000-0001-7494-6841
authors.initials: M
authors.lastname: Müller
authors.affiliation: Department of Plant Biology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain smunne@ub.edu.
authors.forename: Sergi
authors.identifier: http://orcid.org/0000-0001-6523-6848
authors.initials: S
authors.lastname: Munné-Bosch
mesh_terms: D000040:Abscisic Acid / Q000378:metabolism; D003517:Cyclopentanes / Q000378:metabolism; D005030:Ethylenes / Q000378:metabolism*; D010084:Oxidation-Reduction; D054883:Oxylipins / Q000378:metabolism; D010937:Plant Growth Regulators / Q000378:metabolism*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D013312:Stress, Physiological / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D003517:Cyclopentanes; D005030:Ethylenes; D054883:Oxylipins; D010937:Plant Growth Regulators; D010940:Plant Proteins; D014157:Transcription Factors; C011006:jasmonic acid; D000040:Abscisic Acid; C036216:ethylene