title: Copycat innate lymphoid cells dampen gut inflammation.
abstract: The mechanisms whereby the gut mucosa tolerates trillions of commensal bacteria without developing inflammation remain poorly understood. A recent Science article reveals that gut innate lymphoid cells constrain inflammatory T cell responses to commensal bacteria by adopting a strategy usually deployed by thymic epithelial cells to negatively select self-reactive T cells.
authors.affiliation: Institut Hospital del Mar 'Investigacions Mèdiques, Barcelona Biomedical Research Park, Barcelona, Spain.
authors.forename: Giuliana
authors.initials: G
authors.lastname: Magri
authors.affiliation: Institut Hospital del Mar 'Investigacions Mèdiques, Barcelona Biomedical Research Park, Barcelona, Spain.|Catalan Institute for Research and Advanced Studies (ICREA), Barcelona Biomedical Research Park, Barcelona, Spain.|Immunology Institute, Department of Medicine, Division of Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
authors.forename: Andrea
authors.initials: A
authors.lastname: Cerutti
mesh_terms: D000818:Animals; D001419:Bacteria / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D003106:Colon / Q000382:microbiology*; D005260:Female; D000949:Histocompatibility Antigens Class II / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate; D015212:Inflammatory Bowel Diseases / Q000382:microbiology*; D008297:Male
chemical_list: D000949:Histocompatibility Antigens Class II