title: [Molecular signatures of breast cancer: What clinical utility?].
abstract: The role of molecular signatures in the adjuvant management of breast cancer remains a debated topic. Discussions should take into account the level of scientific validation, the impact on practice, the expected benefits and financing issues. This article presents the key points for a rational use of commercial molecular signatures.
authors.affiliation: Department of medical oncology, Institut Gustave-Roussy 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France; Inserm U981, Institut Gustave-Roussy 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France. Electronic address: suzette.delaloge@gustaveroussy.fr.
authors.forename: Suzette
authors.initials: S
authors.lastname: Delaloge
authors.affiliation: Department of medical oncology, Institut Gustave-Roussy 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: Mahasti
authors.initials: M
authors.lastname: Saghatchian
authors.affiliation: Department of medical oncology, Institut Gustave-Roussy 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: Amal
authors.initials: A
authors.lastname: Ghouadni
authors.affiliation: Department of medical oncology, Institut Gustave-Roussy 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Fekih
authors.affiliation: Department of medical oncology, Institut Gustave-Roussy 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France; Inserm U981, Institut Gustave-Roussy 114, rue Edouard-Vaillant, 94805 Villejuif cedex, France.
authors.forename: Fabrice
authors.initials: F
authors.lastname: André
mesh_terms: D001943:Breast Neoplasms / Q000188:drug therapy* / Q000235:genetics*; D003132:Commerce; D005260:Female; D020869:Gene Expression Profiling / Q000191:economics / Q000379:methods; D005820:Genetic Testing / Q000379:methods; D006801:Humans; D009362:Neoplasm Metastasis; D011379:Prognosis
keywords: Breast cancer; Cancer du sein; Molecular signatures; Prediction; Prognosis; Pronostic; Prédiction; Signature moléculaire