title: [Care-Dependency in Parkinson's Disease: More Frequent than Assumed?].
abstract: OBJECTIVE
  Parkinson's disease (PD) increases the risk of care-dependency (CDP). While motor functions worsen continuously, the assignment of patients to CDP occurs categorically. It is unknown how many patients are already sufficiently severely impaired to be categorised as CDP yet do not have an officially acknowledged level of CDP.
  
  
  METHODS
  A random sample of 1,449 PD outpatients was clinically characterised by office-based neurologists, including impairments of activities of daily living (ADL with the Unified Parkinson's Disease Rating scale (UPDRS subscale II) as well as regarding the presence of dementia according to DSM-IV criteria and the Mini-Mental State Exam (MMSE). Depression was screened for with the Montgomery-Asberg Depression Rating Scale (MADRS). For each patient the officially acknowledged level of CDP was documented; for patients without official CDP level, the clinician appraised whether the patient was care-dependent anyhow.
  
  
  RESULTS
  266 patients (18.3%) were officially acknowledged as care-dependent, while n=121 patients (8.5%) were not, yet were appraised to be care-dependent according to the clinician. Compared to non-CDP patients, they differed on every measure considered. Compared to patients with an official CDP, their PD duration was significantly shorter (6.0 vs. 8.0 years, p<0.01) and they were less severely impaired in ADL (13.3 vs. 15.5, p<0.01). They did not differ regarding the rates of dementia (52.9 vs. 44.9%, p=0.203) or depression according to the MADRS (13.1 vs. 13.1, p=0.989).
  
  
  CONCLUSIONS
  ADL impairments are the most important predictor for CDP while dementia and depression are not considered despite the impairments that are additionally caused by them.
authors.affiliation: Klinische Epidemiologie, Leibniz-Institut für Präventionsforschung und Epidemiologie (BIPS GmbH), Bremen.
authors.forename: O
authors.initials: O
authors.lastname: Riedel
mesh_terms: D000368:Aged; D017028:Caregivers / Q000523:psychology* / Q000706:statistics & numerical data*; D015897:Comorbidity; D003704:Dementia / Q000453:epidemiology* / Q000523:psychology; D003858:Dependency, Psychological; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D010300:Parkinson Disease / Q000453:epidemiology* / Q000523:psychology*; D012307:Risk Factors