title: Is there any relationship between ABO/Rh blood group and patients with pre-eclampsia?
abstract: OBJECTIVE
  The purpose of the present study was to evaluate the association between pre-eclampsia and blood groups in a group of pregnant women hospitalized in a University Hospital in Porto Alegre, Brazil - Hospital São Lucas (HSL)/PUCRS.
  
  
  METHODS
  Our sample consisted of 10,040 pregnant women admitted to the maternity department of HSL between 2005 and 2010. The patients were reviewed retrospectively for inclusion. Medical records of 414 women were diagnosed as preeclampsia/eclampsia and 9611 women were identified to the control group. The patients were divided into two groups: the group with preeclampsia/eclampsia and the control group, and their blood groups were considered. Data were analyzed using SPSS for Windows version 17.0. Categorical data were summarized by counts and percentages, with the statistical significance evaluated by the Chi-square test. The null hypothesis was rejected when p<0.05.
  
  
  METHODS
  Maternal parameters were compared between control group and pre-eclampsia, respectively, Systolic Blood Pressure (117±19.98 vs. 165±19.99); Diastolic Blood Pressure (73±14.23 vs. 106±14.24) and maternal weight at booking (73±33 vs. 83±33). For all data: mean+SD; p<0.05. In relation to blood groups, firstly they were stratified by Rh and ABO phenotypes, separately. After that the groups were put together.
  
  
  RESULTS
  No differences in blood group distribution were observed between controls and pre-eclampsia for any analysis. (p>0.05).
  
  
  CONCLUSIONS
  When we adopted stricter criteria for pre-eclampsia and a large sample from the same region we noted that the results did not show any association between blood groups and the development of pre-eclampsia.
authors.affiliation: Nephrology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas da PUCRS, 2nd Floor, Room 19, Avenida Ipiranga, 6690 - 90610-000 Jardim Botânico, Porto Alegre, Brazil. Electronic address: martarh@yahoo.com.br.
authors.forename: Marta R
authors.initials: MR
authors.lastname: Hentschke
authors.affiliation: Nephrology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas da PUCRS, 2nd Floor, Room 19, Avenida Ipiranga, 6690 - 90610-000 Jardim Botânico, Porto Alegre, Brazil. Electronic address: fezinhabc@gmail.com.
authors.forename: Fernanda B
authors.initials: FB
authors.lastname: Caruso
authors.affiliation: Nephrology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas da PUCRS, 2nd Floor, Room 19, Avenida Ipiranga, 6690 - 90610-000 Jardim Botânico, Porto Alegre, Brazil. Electronic address: leticiagpaula@terra.com.br.
authors.forename: Letícia G
authors.initials: LG
authors.lastname: Paula
authors.affiliation: Nephrology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas da PUCRS, 2nd Floor, Room 19, Avenida Ipiranga, 6690 - 90610-000 Jardim Botânico, Porto Alegre, Brazil. Electronic address: gutokmedeiros@gmail.com.
authors.forename: Augusto K
authors.initials: AK
authors.lastname: Medeiros
authors.affiliation: Nephrology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas da PUCRS, 2nd Floor, Room 19, Avenida Ipiranga, 6690 - 90610-000 Jardim Botânico, Porto Alegre, Brazil. Electronic address: ggadonski@yahoo.com.br.
authors.forename: Giovani
authors.initials: G
authors.lastname: Gadonski
authors.affiliation: Nephrology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas da PUCRS, 2nd Floor, Room 19, Avenida Ipiranga, 6690 - 90610-000 Jardim Botânico, Porto Alegre, Brazil. Electronic address: ivan.antonello@pucrs.br.
authors.forename: Ivan C
authors.initials: IC
authors.lastname: Antonello
authors.affiliation: Division of Hypertension, Department of Nephrology, Hypertension, Clinical Pharmacology and clinical Research, University of Bern, Berne, Switzerland. Electronic address: hiten.mistry@kcl.ac.uk.
authors.forename: Hiten D
authors.initials: HD
authors.lastname: Mistry
authors.affiliation: Nephrology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas da PUCRS, 2nd Floor, Room 19, Avenida Ipiranga, 6690 - 90610-000 Jardim Botânico, Porto Alegre, Brazil. Electronic address: cepolif@pucrs.br.
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Poli-de-Figueiredo
authors.affiliation: Nephrology, School of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul, Hospital São Lucas da PUCRS, 2nd Floor, Room 19, Avenida Ipiranga, 6690 - 90610-000 Jardim Botânico, Porto Alegre, Brazil. Electronic address: bart@pucrs.br.
authors.forename: Bartira E
authors.initials: BE
authors.lastname: Pinheiro da Costa
keywords: ABO blood-group system; Hypertension; Immunological; Pregnancy-induced; Prenatal care; Rh blood-group system