title: [Combination of a universal antidote and temporary skin substitute for chemical burns: Extended case report].
abstract: In this article we describe our experiences in the treatment of chemical burns with Diphoterine(®) solution and Suprathel(®) as a temporary skin substitute material, a treatment which in the past was not commonly used for this pattern of injuries. In the study period from October 2012 to December 2013 we treated five patients (four male and one female including two children and three adults) with chemical burns by decontamination with Diphoterine(®) and wound covering with Suprathel(®). The control group included five patients with similar injury patterns who were treated with Diphoterine(®) and occlusive wound dressings. No wound infections occurred in any of the five cases and no interactions were observed between Suprathel(®) and the chemical substance involved. In four cases the skin areas with IIa-IIb degree damage showed good wound healing and only slight scarring in the follow-up after 3 months and one of the five patients had to be treated surgically. Suprathel(®) can be used as a temporary skin substitute for the treatment of skin burns and is also available for the treatment of chemical burns.
authors.affiliation: Sektion für Plastische und Handchirurgie, Intensiveinheit für Schwerbrandverletzte, Universitätsklinikum Schleswig-Holstein, Campus Lübeck Ratzeburger Alle 160, 23538, Lübeck, Deutschland, liodaki.eirini@gmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Liodaki
authors.forename: B E
authors.initials: BE
authors.lastname: Schopp
authors.forename: J
authors.initials: J
authors.lastname: Lindert
authors.forename: R
authors.initials: R
authors.lastname: Krämer
authors.forename: T
authors.initials: T
authors.lastname: Kisch
authors.forename: P
authors.initials: P
authors.lastname: Mailänder
authors.forename: F
authors.initials: F
authors.lastname: Stang
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000931:Antidotes / Q000008:administration & dosage*; D001458:Bandages; D002057:Burns, Chemical / Q000175:diagnosis / Q000628:therapy*; D002614:Chelating Agents / Q000008:administration & dosage; D002648:Child; D003131:Combined Modality Therapy; D003666:Decontamination / Q000379:methods; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009930:Organic Chemicals / Q000008:administration & dosage; D011091:Polyesters / Q000627:therapeutic use*; D017768:Skin, Artificial; D016896:Treatment Outcome; D014945:Wound Healing; D055815:Young Adult
chemical_list: D000931:Antidotes; D002614:Chelating Agents; D009930:Organic Chemicals; D011091:Polyesters; C472007:diphoterine; C527789:poly(lactide-co-trimethylenecarbonate-co-epsilon-caprolactone)