title: Is Canine Eruption Velocity Affected by the Presence of Allograft Within a Repaired Alveolar Cleft?
abstract: OBJECTIVE
  To assess the rate of canine eruption in alveolar clefts repaired with cancellous autograft versus cancellous autograft mixed with allograft.
  
  
  METHODS
  This was a retrospective cohort study of patients in mixed dentition who underwent primary repair of uni- or bilateral alveolar cleft defects. Patients were divided into 2 groups based on the method of bony reconstruction (group 1, iliac crest autograft; group 2, iliac crest autograft harvested through a minimal access approach and mixed 1:2 with demineralized bone allograft). Secondary predictor variables were demographic and anatomic factors potentially related to canine eruption. The outcome variable was the velocity of canine eruption, measured as the change in vertical distance from the incisal edge to the maxillary occlusal plane (millimeters per month). Descriptive, bivariate, and linear regression statistics were computed.
  
  
  RESULTS
  The study sample included 57 alveolar cleft defects; 19 were repaired with autograft alone and 38 were repaired with autograft plus allograft. The sample's mean age was 9.9 ± 2.3 years at the time of repair. Thirty-one clefts (54.4%) were part of a bilateral deformity. Canine root formation was 50% complete at the time of surgery in most patients (59.6%). Mean duration of follow-up was 23.7 ± 13.2 months. Mean canine eruption velocity was 0.20 ± 0.18 mm per month and was not associated with the method of bony repair (P = .58).
  
  
  CONCLUSIONS
  The use of allograft bone to augment bone graft volume results in similar rates of canine eruption compared with autograft bone alone.
authors.affiliation: Resident, Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD.
authors.forename: Srinivas M
authors.initials: SM
authors.lastname: Susarla
authors.affiliation: Private Practice, Greensboro, NC; Department of Pediatric Dentistry, Children's Hospital of Pittsburgh, Pittsburgh, PA.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Andrews
authors.affiliation: Resident, Department of Pediatric Dentistry, Children's Hospital of Pittsburgh, Pittsburgh, PA.
authors.forename: Nermeen
authors.initials: N
authors.lastname: Hilal
authors.affiliation: Resident, Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD.
authors.forename: Edward W
authors.initials: EW
authors.lastname: Swanson
authors.affiliation: Resident, Department of Pediatric Dentistry, University of Maryland School of Dentistry, Baltimore, MD.
authors.forename: Harlyn K
authors.initials: HK
authors.lastname: Susarla
authors.affiliation: Assistant Professor, Department of Pediatric Dentistry, Children's Hospital of Pittsburgh, Pittsburgh, PA.
authors.forename: Brian S
authors.initials: BS
authors.lastname: Martin
authors.affiliation: Associate Professor, Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD; Department of Plastic and Reconstructive Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA. Electronic address: akumar40@jhu.edu.
authors.forename: Anand R
authors.initials: AR
authors.lastname: Kumar
mesh_terms: D064591:Allografts; D064728:Alveolar Bone Grafting; D003481:Cuspid; D006801:Humans; D012189:Retrospective Studies; D014078:Tooth Eruption