title: [Quality of life in patients with prostate cancer: validation of an instrument for clinical practice].
abstract: OBJECTIVE
  Currently there are instruments to evaluate the different features of the impact on quality of life in those patients with prostate cancer undergoing any type of treatment, but most of them have 50 or more questions and they are difficult to apply in clinical practice. An English validation of a shortened version of the EPIC (Expanded Prostate Cancer Composite), the most used instrument to measure the quality of life in patients with prostate cancer, has been published recently. This version called EPIC-CP (Expanded Prostate Cancer Composite-Clinical Practice) consists of 16 questions arranged in a page, for easy and rapid clinical application. The objective of this work is to validate a Spanish version of the EPIC-CP.
  
  
  METHODS
  An inversa-directa Spanish translation of the original version was performed. The EPIC-CP and EQ5D questionnaires were applied to 46 patients eligible to be subjected to different treatments - open prostatectomy (OP), Robotic Prostatectomy (RP), brachytherapy (Br) or conformational radiotherapy (CR) - and 82 patients already treated (9 OP, 13 RP, 7 Br, 4 CR). For reliability evaluation, the Cronbach's alpha was used to test the internal consistency for each domain of the EPIC-CP. Treated and untreated patients' scores were compared with the Wilcoxon range sum test to assess the sensitivity to change.
  
  
  RESULTS
  Cronbach's alpha was elevated in all the EPIC-CP domains (near or greater than 0.7), indicating a high internal consistency. There was no significant difference in age and educational level between treated and untreated patients. We found significant differences between treated and untreated patients in the total EPIC CP score, in the domains of urinary incontinence, bowel function, sexual function and hormonal function.
  
  
  CONCLUSIONS
  The Spanish version of the EPIC-CP is reliable and valid, so it is a useful tool to measure the quality of life in patients with prostate cancer, as well as the impact of different treatments.
authors.affiliation: Clínica Santa María. Santiago. Chile.
authors.forename: Felipe
authors.initials: F
authors.lastname: Balbontín
authors.affiliation: Clínica Santa María. Santiago. Chile.
authors.forename: Pablo
authors.initials: P
authors.lastname: Marchetti
authors.affiliation: Clínica Santa María. Santiago. Chile.
authors.forename: Sergio
authors.initials: S
authors.lastname: Moreno
authors.affiliation: Clínica Santa María. Santiago. Chile.
authors.forename: José Miguel
authors.initials: JM
authors.lastname: Cabello
authors.affiliation: Servicio de Urología Hospital del Salvador. Santiago. Chile.
authors.forename: Christian
authors.initials: C
authors.lastname: Urzúa
authors.affiliation: Servicio de Urología Hospital del Salvador. Santiago. Chile.
authors.forename: Andrés
authors.initials: A
authors.lastname: Silva
authors.affiliation: Servicio de Urología Hospital del Salvador. Santiago. Chile.
authors.forename: Javier
authors.initials: J
authors.lastname: Avilés
authors.affiliation: Servicio de Radioterapia Fundación Arturo López Pérez. Santiago. Chile.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Badínez
authors.affiliation: Servicio de Radioterapia Fundación Arturo López Pérez. Santiago. Chile.
authors.forename: Jazmín
authors.initials: J
authors.lastname: García
authors.affiliation: Servicio de Radioterapia Fundación Arturo López Pérez. Santiago. Chile.
authors.forename: Apolo
authors.initials: A
authors.lastname: Salgado
authors.affiliation: Clínica Santa María. Santiago. Chile.
authors.forename: Eugenio
authors.initials: E
authors.lastname: Vinez
authors.affiliation: Clínica Santa María. Santiago. Chile.
authors.forename: Isabel
authors.initials: I
authors.lastname: Alliende
authors.affiliation: Clínica Santa María. Santiago. Chile.
authors.forename: Andrea
authors.initials: A
authors.lastname: Canals
authors.affiliation: Clínica Santa María. Santiago. Chile.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Velasco
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000628:therapy*; D011788:Quality of Life; D011795:Surveys and Questionnaires