title: Comparison of maternal and fetal outcomes of IVF and spontaneously conceived twin pregnancies: three year experience of a tertiary hospital.
abstract: OBJECTIVE
  The aim of this study was to compare maternal and fetal outcomes of spontaneously conceived and in-vitro fertilization (IVF) twin pregnancies that were admitted to our obstetric clinic and delivered between January 1, 2011 to November 1, 2014.
  
  
  METHODS
  A total of 84 twin pregnancies were enrolled for the study and divided into two groups: group 1 as IVF (n = 19) and group 2 as spontaneously conceived (n = 65) twin pregnancies. Data of neonatal various morbidities needs neonatal intensive care unit (NICU) such as necrotizing enterocolitis (NEC), bronchopulmonary dysplasia (BPD), sepsis, retinopathy of prematurity (ROP), and intraventricular hemorrhage (IVH) and maternal morbidities such as preeclampsia, eclampsia, postpartum bleeding, gestational diabetes mellitus(GDM) were collected by hospital records.
  
  
  RESULTS
  There were no statistical difference between two groups regarding hypertension related to pregnancy, intrauterine growth retardation, Apgar scores, NICU needs, birth weight and height (P > 0.05). The rate of premature rupture of membranes, maternal age, antenatal anemia and premature birth were detected higher in IVF group when compared with the other group (P < 0.05).
  
  
  CONCLUSIONS
  Although twin pregnancies, regardless of conception method are high risk pregnancies in terms of obstetric and perinatal outcomes, premature rupture of membranes, maternal age, antenatal anemia and premature birth risks are higher in IVF twin pregnancies.
authors.affiliation: Department of Obstetrics and Gynecology, Ümraniye Medical and Research Hospital İstanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Göçmen
authors.affiliation: Department of Neonatology, Ümraniye Medical and Research Hospital İstanbul, Turkey.
authors.forename: Şirin
authors.initials: Ş
authors.lastname: Güven
authors.affiliation: Department of Obstetrics and Gynecology, Ümraniye Medical and Research Hospital İstanbul, Turkey.
authors.forename: Simge
authors.initials: S
authors.lastname: Bağci
authors.affiliation: Department of Obstetrics and Gynecology, Ümraniye Medical and Research Hospital İstanbul, Turkey.
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Çekmez
authors.affiliation: Department of Obstetrics and Gynecology, Ümraniye Medical and Research Hospital İstanbul, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Şanlıkan
keywords: IVF; NICU; fetal outcome; maternal outcome; twin