title: [First Episode Psychosis: Relationship of Symptoms, Initial Treatment and Clinical Response].
abstract: OBJECTIVE
  It was aimed to explore the relationship of clinical psychopathology and treatment response with "duration of untreated psychosis" (DUP) and "duration of untreated illness"(DUI) in 15-20 years old (mean age: 17,34 ± 1.69) inpatients in Turkey.
  
  
  METHODS
  Mood disorders with psyhotic features were grouped as affective psychoses (18 patients, mean age: 17,28 ± 1,75); schizophrenia, schiozophreniform disorder and other psychotic disorders were grouped as non-affective psychoses (25 patients, mean age: 17,38 ± 1,68). 43 patiens (11 females, 32 males) were evaluated for acute treatment response with Positive and Negative Scale-PANSS and Clinical Global Impressions Scale-CGI.
  
  
  RESULTS
  Mean DUP was determined as 6,5 ± 12,4 weeks, mean DUI was determined as 37,8 ± 49,8 weeks. For the affective psychosis (AP) group; mean DUP was 1,9 ± 1,2 weeks, mean DUI was 24,6 ± 37,1 weeks, for the non-affective psychosis (NAP) group; mean DUP was 9,8 ± 15,5 weeks, mean DUI was 47,3 ± 55,9 weeks. Treatment response was better for the non-affective psychosis group and for the patients who had earlier access to treatment. Shorter DUP and DUI was related with better PANSS negative symptom severity at the time of the discharge.
  
  
  CONCLUSIONS
  Better treatment response related with shorter DUP and DUI reveals the significance of early treatment for the disease prognosis.
authors.forename: Eren
authors.initials: E
authors.lastname: Yıldızhan
authors.forename: Ahmet
authors.initials: A
authors.lastname: Türkcan
authors.forename: Sibel
authors.initials: S
authors.lastname: İnan
authors.forename: Zehra
authors.initials: Z
authors.lastname: Erenkuş
authors.forename: Özhan
authors.initials: Ö
authors.lastname: Yalçın
authors.forename: Ayten
authors.initials: A
authors.lastname: Erdoğan
mesh_terms: D000293:Adolescent; D014150:Antipsychotic Agents / Q000008:administration & dosage; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage; D006801:Humans; D007902:Length of Stay; D008297:Male; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy; D014421:Turkey; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents; D006220:Haloperidol