title: [Sleep disturbances in Parkinson's disease: characteristics, evaluation and therapeutic approaches].
abstract: BACKGROUND
  Parkinson's disease is a well known representent of the movement disorder group of neurological disorders. The diagnosis of Parkinson's disease is based on specific symptoms and signs of movement abnormalities. In addition to classic motor symptoms, Parkinson's disease has characteristic non-motor features, and some of these emerges the classic signs.
  
  
  OBJECTIVE
  The authors discuss characteristics and therapeutic interventions in Parkinson's disease related sleep disturbances.
  
  
  METHODS
  The authors reviewed and summarised literature data on sleep disorders in Parkinson's disease published in the PubMed database up to January 2015.
  
  
  RESULTS
  Sleep problems are important non-motor complains (insomnia, hypersomnia, REM behaviour disorder, sleep apnea and restless legs syndrome). The neurodegenerative process of the brain-stem, the effect of symptoms of Parkinson's disease on sleep and concomitant sleep disorders constitute the background of the patient's complains.
  
  
  CONCLUSIONS
  Appropriate diagnosis and therapy of the consequential or concomitant sleep disorders in Parkinson's disease will help to improve the patient's quality of life.
authors.affiliation: Klinikai Központ, Neurológiai Klinika, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs, Rét u. 2., 7623.
authors.forename: Béla
authors.initials: B
authors.lastname: Faludi
authors.forename: József
authors.initials: J
authors.lastname: Janszky
authors.forename: Sámuel
authors.initials: S
authors.lastname: Komoly
authors.forename: Norbert
authors.initials: N
authors.lastname: Kovács
mesh_terms: D000978:Antiparkinson Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001933:Brain Stem / Q000503:physiopathology; D002940:Circadian Rhythm; D015259:Dopamine Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology* / Q000517:prevention & control; D011788:Quality of Life; D020187:REM Sleep Behavior Disorder / Q000209:etiology / Q000628:therapy; D012148:Restless Legs Syndrome / Q000209:etiology / Q000628:therapy; D057566:Self Report; D012890:Sleep; D020181:Sleep Apnea, Obstructive / Q000209:etiology / Q000628:therapy; D012892:Sleep Deprivation; D007319:Sleep Initiation and Maintenance Disorders / Q000209:etiology / Q000628:therapy; D012894:Sleep Stages; D012893:Sleep Wake Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control / Q000628:therapy*; D011795:Surveys and Questionnaires
chemical_list: D000978:Antiparkinson Agents; D015259:Dopamine Agents
keywords: Parkinson-kór; Parkinson’s disease; REM behaviour disorder; REM-magatartászavar; alvási apnoe; alvászavar; insomnia; nyugtalan láb szindróma; restless legs syndrome; sleep apnoe; sleep disturbances; terápia; therapy