title: Nickel-catalyzed asymmetric transfer hydrogenation of conjugated olefins.
abstract: Asymmetric transfer hydrogenation of electron-deficient olefins is realized with nickel catalysts supported by strongly σ-donating bisphosphines. Deuterium labeling experiments point to a reaction sequence of formate decarboxylation, asymmetric hydride insertion and non-stereoselective protonation of resulting nickel enolates.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371. jrzhou@ntu.edu.sg.
authors.forename: Siyu
authors.initials: S
authors.lastname: Guo
authors.forename: Peng
authors.initials: P
authors.lastname: Yang
authors.forename: Jianrong Steve
authors.initials: JS
authors.lastname: Zhou
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D005561:Formates / Q000737:chemistry; D006865:Hydrogenation; D009532:Nickel / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D011522:Protons; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D005561:Formates; D010720:Phosphines; D011522:Protons; C030544:formic acid; D009532:Nickel; C044646:phosphine