title: Melanotic neuroectodermal tumour of infancy: surgical and chemotherapeutic management.
abstract: Melanotic neuroectodermal tumour of infancy (MNTI) is a rare pigmented neoplasm of neural crest origin. It usually presents in the first year of life in the maxilla as a fast growing lesion. We describe the case of a 3-month-old boy who presented with an enlarging swelling of left maxillary alveolus. He was treated with combined surgical and chemotherapy modalities. MNTI is complicated by high recurrence rate, local invasion and malignancy has been reported. This report describes the diagnosis, treatment and follow-up of recurrent MNTI.
authors.affiliation: Department of Oral and Maxillofacial Surgery, St James's Hospital, Our Lady's Children's Hospital Crumlin, Dublin, Ireland. colmmurphy1978@gmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Murphy
authors.affiliation: Department of Paediatric Oncology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.
authors.forename: J
authors.initials: J
authors.lastname: Pears
authors.affiliation: Department of Oral and Maxillofacial Surgery, St James's Hospital, Our Lady's Children's Hospital Crumlin, Dublin, Ireland.
authors.forename: G J
authors.initials: GJ
authors.lastname: Kearns
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D006801:Humans; D007223:Infant; D008297:Male; D008441:Maxillary Neoplasms / Q000188:drug therapy / Q000601:surgery*; D017600:Neuroectodermal Tumor, Melanotic / Q000188:drug therapy / Q000601:surgery*; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014750:Vincristine
keywords: Maxillary tumour; Neuroectodermal tumour