title: A phthalazine-based two-in-one chromogenic receptor for detecting Co(2+) and Cu(2+) in an aqueous environment.
abstract: A new multifunctional and highly selective chemosensor for Co(2+) and Cu(2+) was designed and synthesized. could simultaneously detect both Co(2+) and Cu(2+) by changing its color from pale yellow to pink and to orange in a near-perfect aqueous solution. The binding modes of to Co(2+) and Cu(2+) were determined to be a 2 : 1 complexation stoichiometry through Job's plot, ESI-mass spectrometry analysis and (1)H NMR titration. The detection limits (1.5 and 2.1 μM) of for Co(2+) and Cu(2+) were lower than the DEP guidelines (1.7 μM for Co(2+)) and the WHO guidelines (31.5 μM for Cu(2+)) for drinking water. The chemosensor could be used to quantify Co(2+) and Cu(2+) in water samples. Moreover, could be used as a practical, visible colorimetric test kit for both Co(2+) and Cu(2+). The sensing mechanisms of Co(2+) and Cu(2+) by were supported by theoretical calculations.
authors.affiliation: Department of Fine Chemistry and Department of Interdisciplinary Bio IT Materials, Seoul National University of Science and Technology, Seoul 139-743, Korea. chealkim@seoultech.ac.kr.
authors.forename: Jae Jun
authors.initials: JJ
authors.lastname: Lee
authors.forename: Ye Won
authors.initials: YW
authors.lastname: Choi
authors.forename: Ga Rim
authors.initials: GR
authors.lastname: You
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Lee
authors.forename: Cheal
authors.initials: C
authors.lastname: Kim
mesh_terms: D002413:Cations, Divalent / Q000032:analysis; D002863:Chromogenic Compounds / Q000737:chemistry*; D003035:Cobalt / Q000032:analysis*; D003124:Colorimetry / Q000379:methods; D003300:Copper / Q000032:analysis*; D060766:Drinking Water / Q000032:analysis*; D057230:Limit of Detection; D008958:Models, Molecular; D010793:Phthalazines / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
chemical_list: D002413:Cations, Divalent; D002863:Chromogenic Compounds; D060766:Drinking Water; D010793:Phthalazines; D012545:Schiff Bases; D003035:Cobalt; D003300:Copper; C043388:phthalazine