title: Perfluorinated chemicals in blood serum of inhabitants in central Poland in relation to gender and age.
abstract: The goal of this paper is to determine concentrations of seven selected perfluoroalkylated substances (PFASs): perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA), perfluorohexane sulfonic acid (PFHxS), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluoroundecanoic acid (PFUnDA), perfluorododecanoic acid (PFDoDA) in the blood serum of men and women of reproductive age from the central region of Poland. The relation between sex of tested subjects and the levels of compounds in blood serum of humans will also be considered and analysed as an element of the risk assessment. The study was made on the blood serum samples collected from 253 women and 176 men of reproductive age between 20 and 44 years from Warsaw and surrounding areas. Higher concentrations of five (PFOS, PFOA, PFNA, PFDA, PFUnDA) from among seven selected PFASs were observed in men in comparison to women from the same populations. Only the concentrations of PFHxS and PFDoDA were slightly higher in women than in men. These differences were statistically significant in all cases, except for PFUnDA. The hypothesis that the concentrations of said compounds increase with age of the test subjects, regardless of gender has not been confirmed.
authors.affiliation: Department of Toxicology and Risk Assessment, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: kgoralczyk@pzh.gov.pl.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Góralczyk
authors.affiliation: Department of Radiation Hygiene and Radiobiology, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: kpachocki@pzh.gov.pl.
authors.forename: Krzysztof A
authors.initials: KA
authors.lastname: Pachocki
authors.affiliation: Department of Toxicology and Risk Assessment, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: ahernik@pzh.gov.pl.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Hernik
authors.affiliation: Department of Toxicology and Risk Assessment, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: pstrucinski@pzh.gov.pl.
authors.forename: Paweł
authors.initials: P
authors.lastname: Struciński
authors.affiliation: Department of Toxicology and Risk Assessment, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: kczaja@pzh.gov.pl.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Czaja
authors.affiliation: Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Sweden Lund University, S-221 85 Lund, Sweden. Electronic address: Christian.Lindh@med.lu.se.
authors.forename: Christian H
authors.initials: CH
authors.lastname: Lindh
authors.affiliation: Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Sweden Lund University, S-221 85 Lund, Sweden. Electronic address: bo_a.jonsson@med.lu.se.
authors.forename: Bo A G
authors.initials: BA
authors.lastname: Jönsson
authors.affiliation: Division of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 2, 3584 CM Utrecht, The Netherlands. Electronic address: V.C.Lenters@uu.nl.
authors.forename: Virissa
authors.initials: V
authors.lastname: Lenters
authors.affiliation: Department of Toxicology and Risk Assessment, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: wkorcz@pzh.gov.pl.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Korcz
authors.affiliation: Department of Toxicology and Risk Assessment, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: mminorczyk@pzh.gov.pl.
authors.forename: Maria
authors.initials: M
authors.lastname: Minorczyk
authors.affiliation: Department of Toxicology and Risk Assessment, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: mmatuszak@pzh.gov.pl.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Matuszak
authors.affiliation: Department of Toxicology and Risk Assessment, National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland. Electronic address: k.ludwicki@pzh.gov.pl.
authors.forename: Jan K
authors.initials: JK
authors.lastname: Ludwicki
mesh_terms: D000328:Adult; D017738:Alkanesulfonic Acids / Q000097:blood; D002210:Caprylates / Q000097:blood; D003652:Decanoic Acids / Q000097:blood; D004781:Environmental Exposure / Q000032:analysis* / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D005466:Fluorocarbons / Q000097:blood*; D006801:Humans; D007850:Lauric Acids / Q000097:blood; D008297:Male; D008875:Middle Aged; D011044:Poland; D044967:Serum; D055815:Young Adult
chemical_list: D017738:Alkanesulfonic Acids; D002210:Caprylates; D003652:Decanoic Acids; D004785:Environmental Pollutants; D005466:Fluorocarbons; D007850:Lauric Acids; C036567:perfluorodecanoic acid; C023036:perfluorooctanoic acid; C076994:perfluorooctane sulfonic acid; C078626:perflexane; C522391:perfluorododecanoic acid
keywords: PFASs; PFOA; PFOS; POPs; Serum levels