title: [One Case of Multiple Myeloma with Central Never System Infiltration].
abstract: OBJECTIVE
  To analyses and summarize a case of multiple myeloma with disseminated infiltration in central nervous system.
  
  
  METHODS
  The results of laboratorial examination and clinical data were analyzed and compared in the light of published literatures.
  
  
  RESULTS
  The headache and diplopia were caused by infiltration of multiple myeloma cells to the central nervous system. Unlike those reported in the literatures, this case was a rare case of disseminated infiltration inside the brain, and plasma cells were CD56+, this patient has not yet accepted any multiple myeloma-associated treatment as like that reported in the literatures. And different from cases reported, this patient showed a good response to the intrathecal chemotherapy.
  
  
  CONCLUSIONS
  Whether this good response is due to a heterogeneity of MM or effect of treatment-associated drug is still to be decided.
authors.affiliation: Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Liu
authors.affiliation: Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors.forename: Fu-Xu
authors.initials: FX
authors.lastname: Wang
authors.affiliation: Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Yang
authors.affiliation: Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors.forename: Shu-Peng
authors.initials: SP
authors.lastname: Wen
authors.affiliation: Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Luo
authors.affiliation: Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors.forename: Zi-Wei
authors.initials: ZW
authors.lastname: Zhou
authors.affiliation: Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China. E-mail: zhxjhbmu@126.com.
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: ZhANG
mesh_terms: D002490:Central Nervous System; D006801:Humans; D009101:Multiple Myeloma; D010950:Plasma Cells