title: Expression of CD105 in tumor angiogenesis a comparative study (ameloblastoma, keratocystic odontogenic tumor and dentigerous cyst).
abstract: BACKGROUND
  Demonstrate the expression of CD105 (angiogenetic marker) in ameloblastoma (AM), keratocystic odontogenic tumor (KCOT) and dentigerous cyst (DC).
  
  
  METHODS
  Assessment of microvessel density (MVD) in 70 cases, including 20 KCOT, 20 DC and 20 solid AMs. Assessment of MVD should be done as the mean number of microvessels per high-power-field.
  
  
  RESULTS
  AM and KCOT demonstrated a higher mean value of 7.98 (±2.70) and 6.25 (±2.88) respectively while DC demonstrated a lower mean of 3.75 (±1.42). There was no statistically significant difference between AM and KCOT (P > 0.05). The difference between AM and DC; and between KCOT and DC were statistically significant (P < 0.05).
  
  
  CONCLUSIONS
  The present study suggested that angiogenesis may be one of the mechanisms possibly contributing to the different biological behaviors of KCOT, DCs and solid AMs.
authors.affiliation: Assistant Professor, Department of Oral Pathology, AME'S Dental College and Hospital, Raichur, Karnataka, India.
authors.forename: Dandena Vinay
authors.initials: DV
authors.lastname: Kumar
authors.affiliation: Professor and Head, Oral Pathology, Rajiv Gandhi Institute of Dental Sciences, Bengaluru; Karnataka, India.
authors.forename: Satheavanthan
authors.initials: S
authors.lastname: Hemavathy
authors.affiliation: Assistant Professor, Oral Pathology, MA Rangoonwala Dental College, Pune, Maharashtra, India.
authors.forename: Dinraj
authors.initials: D
authors.lastname: Kulkarni
authors.affiliation: Assistant Professor, Department of Oral Pathology, AME'S Dental College and Hospital, Raichur, Karnataka, India.
authors.forename: Pradeep Mattighatta
authors.initials: PM
authors.lastname: Rudraiah
authors.affiliation: Assistant Professor, Department of Oral Surgery, AME'S Dental College and Hospital, Raichur, Karnataka, India.
authors.forename: Santosh Kumar
authors.initials: SK
authors.lastname: Sidramayya Mathpati
authors.affiliation: Assistant Professor, Department of Conservative and Endodontics, HKDET's Trust Dental College and Hospitak, Humnabad, Bidar, Karnataka, India.
authors.forename: Sharan
authors.initials: S
authors.lastname: Priya
keywords: Ameloblastoma; angiogenesis; dentigerous cyst; keratocystic odontogenic tumor