title: [Comparison of Quantification of Myocardial Infarct Size by One Breath Hold Single Shot PSIR Sequence and Segmented FLASH-PSIR Sequence at 3. 0 Tesla MR].
abstract: OBJECTIVE
  To compare the two sequences [single shot true-FISP-PSIR (single shot-PSIR) and segmented-turbo-FLASH-PSIR (segmented-PSIR)] in the value of quantification for myocardial infarct size at 3. 0 tesla MRI.
  
  
  METHODS
  38 patients with clinical confirmed myocardial infarction were served a comprehensive gadonilium cardiac MRI at 3. 0 tesla MRI system (Trio, Siemens). Myocardial delayed enhancement (MDE) were performed by single shot-PSIR and segmented-PSIR sequences separatedly in 12-20 min followed gadopentetate dimeglumine injection (0. 15 mmol/kg). The quality of MDE images were analysed by experienced physicians. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) between the two techniques were compared. Myocardial infarct size was quantified by a dedicated software automatically (Q-mass, Medis).
  
  
  RESULTS
  All objectives were scanned on the 3. 0T MR successfully. No significant difference was found in SNR and CNR of the image quality between the two sequences (P>0. 05), as well as the total myocardial volume, between two sequences (P>0. 05). Furthermore, there were still no difference in the infarct size [single shot-PSIR (30. 87 ± 15. 72) mL, segmented-PSIR (29. 26±14. 07) ml], ratio [single shot-PSIR (22. 94%±10. 94%), segmented-PSIR (20. 75% ± 8. 78%)] between the two sequences (P>0. 05). However, the average aquisition time of single shot-PSIR (21. 4 s) was less than that of the latter (380 s).
  
  
  CONCLUSIONS
  Single shot-PSIR is equal to segmented-PSIR in detecting the myocardial infarct size with less acquisition time, which is valuable in the clinic application and further research.
authors.forename: Wei
authors.initials: W
authors.lastname: Cheng
authors.forename: Shu
authors.initials: S
authors.lastname: Cai
authors.forename: Jia-yu
authors.initials: JY
authors.lastname: Sun
authors.forename: Chun-chao
authors.initials: CC
authors.lastname: Xia
authors.forename: Zhen-lin
authors.initials: ZL
authors.lastname: Li
authors.forename: Yu-cheng
authors.initials: YC
authors.lastname: Chen
authors.forename: Yao-zu
authors.initials: YZ
authors.lastname: Zhong
mesh_terms: D062485:Breath Holding; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009203:Myocardial Infarction / Q000175:diagnosis*; D009206:Myocardium / Q000473:pathology
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA