title: Plasma antithrombin levels correlate with albumin and total protein in gestational hypertension and preeclampsia.
abstract: OBJECTIVE
  To analyze the antithrombin-III (AT-III) activity in the plasma in relation to the serum albumin and total protein in preeclampsia and gestational hypertension.
  
  
  METHODS
  The medical records of 139 patients who were diagnosed with gestational hypertension (n=33) and preeclampsia (n=106) were reviewed, and the relationships between the activity of AT-III and serum albumin or total protein were evaluated.
  
  
  METHODS
  The plasma AT-III activity in gestational hypertension and preeclampsia was correlated with the serum albumin and TP levels.
  
  
  RESULTS
  There were significant correlations between AT-III activity and albumin in gestational hypertension (r=0.504, p=0.003) and preeclampsia (r=0.343, p=0.003). There were also significant correlations between AT-III activity and TP in gestational hypertension (r=0.619, p=0.001) and preeclampsia (r=0.366, p=0.001). Regression coefficients between AT-III and albumin and between AT-III and TP in gestational hypertension (23.7 and 14.0, respectively) were significantly steeper than those in preeclampsia (14.6 and 9.6, respectively).
  
  
  CONCLUSIONS
  The plasma AT-III activity in gestational hypertension and preeclampsia was correlated with the serum albumin and TP levels. This suggests that AT-III activity is more likely to decrease in gestational hypertension than in preeclampsia.
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Tokyo, Japan. Electronic address: masakiogawa3@gmail.com.
authors.forename: Masaki
authors.initials: M
authors.lastname: Ogawa
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Tokyo, Japan.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Matsuda
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Tokyo, Japan.
authors.forename: Aiko
authors.initials: A
authors.lastname: Kobayashi
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Tokyo, Japan.
authors.forename: Minoru
authors.initials: M
authors.lastname: Mitani
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Tokyo, Japan.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Makino
authors.affiliation: Department of Obstetrics and Gynecology, Tokyo Women's Medical University, Tokyo, Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Matsui
keywords: Albumin; Antithrombin; Gestational hypertension; Obstetric disseminated intravascular coagulation; Preeclampsia