title: Shape-encoded silica microparticles for multiplexed bioassays.
abstract: Shape-encoded silica microparticles for use in multiplexed bioassays were fabricated by using optofluidic maskless lithography (OFML) and tetraethylorthosilicate (TEOS) polymerization. These encoded silica microparticles exhibit excellent bioconjugation properties and negligible non-specific analyte adsorption. Encoded silica microparticles could be useful in a wide variety of applications, including DNA- and protein-based diagnostics.
authors.affiliation: School of Electrical Engineering and Computer Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-744, South Korea. skwon@snu.ac.kr.
authors.forename: Lily Nari
authors.initials: LN
authors.lastname: Kim
authors.forename: Mira
authors.initials: M
authors.lastname: Kim
authors.forename: Keumsim
authors.initials: K
authors.lastname: Jung
authors.forename: Hyung Jong
authors.initials: HJ
authors.lastname: Bae
authors.forename: Jisung
authors.initials: J
authors.lastname: Jang
authors.forename: Yushin
authors.initials: Y
authors.lastname: Jung
authors.forename: Jiyun
authors.initials: J
authors.lastname: Kim
authors.forename: Sunghoon
authors.initials: S
authors.lastname: Kwon
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D004247:DNA / Q000032:analysis; D019937:Diagnostic Techniques and Procedures; D060005:Genotyping Techniques / Q000379:methods; D006367:HeLa Cells; D052161:Human papillomavirus 18 / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D061925:Immobilized Nucleic Acids / Q000737:chemistry; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000821:virology; D058105:Polymerization; D011506:Proteins / Q000032:analysis; D012821:Silanes / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D061925:Immobilized Nucleic Acids; D011506:Proteins; D012821:Silanes; C040733:tetraethoxysilane; D012822:Silicon Dioxide; D004247:DNA