title: Depression of Late Age-Related Macular Degeneration Patients in Korea.
abstract: OBJECTIVE
  The aim of study was to investigate the relationship between depression and age-related macular degeneration (AMD) in Korea treated with intravitreal ranibizumab.
  
  
  METHODS
  This was a cross-sectional study. This study included 107 patients diagnosed with AMD treated with intravitreal ranibizumab. All patients answered the Korean version of the Geriatric Depression Scale (GDS-K), and the prevalence of depression was evaluated. The patients from 1 center were classified into groups with and without depression according to GDS-K. Visual acuity (VA), duration, bilaterality, history of previous treatment for AMD, and comorbidities were assessed and compared between groups. The correlations between GDS-K and other variables were investigated.
  
  
  RESULTS
  The prevalence of depression was 26.2% with AMD treated with intravitreal ranibizumab in this study. In subanalysis, the 23 depressed patients (33.3%) were older (P = 0.022) than the nondepressed. Positive correlations were observed between GDS-K and age, VA of injected eye, VA of better eye, duration of AMD, and the number of previous treatments for AMD.
  
  
  CONCLUSIONS
  This is the first study evaluating the relationship between depression and AMD in Koreans treated with intravitreal ranibizumab. The prevalence of depression in AMD is substantial and similar to those in previous reports. Interventions to diagnose and treat depression in AMD patients are necessary.
authors.affiliation: From the Departments of *Ophthalmology and †Neuropsychiatry, Hanyang University College of Medicine; ‡Department of Ophthalmology, Seoul National University College of Medicine; §Department of Ophthalmology, Korea University College of Medicine; ∥Department of Ophthalmology, Inje University College of Medicine; and ¶Department of Ophthalmology, Kyung Hee University School of Medicine.
authors.forename: Won June
authors.initials: WJ
authors.lastname: Lee
authors.forename: Hee Yoon
authors.initials: HY
authors.lastname: Cho
authors.forename: Dae Ho
authors.initials: DH
authors.lastname: Kim
authors.forename: Hyeong Gon
authors.initials: HG
authors.lastname: Yu
authors.forename: Jaeryung
authors.initials: J
authors.lastname: Oh
authors.forename: Jae Suk
authors.initials: JS
authors.lastname: Kim
authors.forename: Sang Woong
authors.initials: SW
authors.lastname: Moon