title: Management of Noncardiac Comorbidities in Chronic Heart Failure.
abstract: Prevalence of heart failure is increasing, especially in the elderly population. Noncardiac comorbidities complicate heart failure care and are increasingly common in elderly patients with reduced or preserved ejection fraction heart failure, owing to prolongation of patient's lives by advances in chronic heart failure (CHF) management. Common comorbidities include respiratory disease, renal dysfunction, anemia, arthritis, obesity, diabetes mellitus, cognitive dysfunction, and depression. These conditions contribute to the progression of the disease and may alter the response to treatment, partly as polypharmacy is inevitable in these patients. Cardiologists and other physicians caring for patients with CHF need to be vigilant to comorbid conditions that complicate the care of these patients. There is now more guidance on management of noncardiac comorbidities in heart failure, and this article contains a comprehensive review of the most recent updates on management of noncardiac comorbidities in CHF.
authors.affiliation: Department of Cardiology, Ninewells Hospital, Dundee, UK.
authors.forename: Vun Heng
authors.initials: VH
authors.lastname: Chong
authors.affiliation: Division of Medicine and Therapeutics, University of Dundee, Dundee, UK.
authors.forename: Jagdeep
authors.initials: J
authors.lastname: Singh
authors.affiliation: Department of Cardiology, Ninewells Hospital, Dundee, UK.
authors.forename: Helen
authors.initials: H
authors.lastname: Parry
authors.affiliation: Medical School, University of Dundee, Dundee, UK.
authors.forename: Jocelyn
authors.initials: J
authors.lastname: Saunders
authors.affiliation: Medical School, University of Dundee, Dundee, UK.
authors.forename: Farhad
authors.initials: F
authors.lastname: Chowdhury
authors.affiliation: Department of Medicine, Columbia University, New York City, NY, USA.
authors.forename: Donna M
authors.initials: DM
authors.lastname: Mancini
authors.affiliation: Department of Cardiology, Ninewells Hospital, Dundee, UK.
authors.forename: Chim C
authors.initials: CC
authors.lastname: Lang
mesh_terms: D000740:Anemia / Q000188:drug therapy / Q000453:epidemiology; D001168:Arthritis / Q000188:drug therapy / Q000453:epidemiology; D003072:Cognition Disorders / Q000188:drug therapy / Q000453:epidemiology; D003863:Depression / Q000188:drug therapy / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000453:epidemiology; D018450:Disease Progression; D006333:Heart Failure / Q000188:drug therapy* / Q000453:epidemiology*; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology / Q000628:therapy; D009765:Obesity / Q000453:epidemiology / Q000628:therapy; D019338:Polypharmacy; D012140:Respiratory Tract Diseases / Q000188:drug therapy / Q000453:epidemiology; D012307:Risk Factors
keywords: Comorbidities; Drug treatment; Heart failure; Management