title: Progress in the Diagnosis and Classification of Pituitary Adenomas.
abstract: Pituitary adenomas are common neoplasms. Their classification is based upon size, invasion of adjacent structures, sporadic or familial cases, biochemical activity, clinical manifestations, morphological characteristics, response to treatment and recurrence. Although they are considered benign tumors, some of them are difficult to treat due to their tendency to recur despite standardized treatment. Functional tumors present other challenges for normalizing their biochemical activity. Novel approaches for early diagnosis, as well as different perspectives on classification, may help to identify subgroups of patients with similar characteristics, creating opportunities to match each patient with the best personalized treatment option. In this paper, we present the progress in the diagnosis and classification of different subgroups of patients with pituitary tumors that may be managed with specific considerations according to their tumor subtype.
authors.affiliation: Department of Neurosurgery, Hospital Pablo Tobon Uribe and Clinica Medellin , Medellin , Colombia.
authors.forename: Luis V
authors.initials: LV
authors.lastname: Syro
authors.affiliation: Laboratory Medicine, Division of Pathology, St. Michael's Hospital, University of Toronto , Toronto, ON , Canada.
authors.forename: Fabio
authors.initials: F
authors.lastname: Rotondo
authors.affiliation: Department of Endocrinology, Universidad Pontificia Bolivariana , Medellin , Colombia.
authors.forename: Alex
authors.initials: A
authors.lastname: Ramirez
authors.affiliation: Department of Neurosurgery, Australian School of Advanced Medicine, Macquarie University , Sydney, NSW , Australia.
authors.forename: Antonio
authors.initials: A
authors.lastname: Di Ieva
authors.affiliation: Nisantasi Pathology Group , Istanbul , Turkey.
authors.forename: Murat Aydin
authors.initials: MA
authors.lastname: Sav
authors.affiliation: Division of Endocrinology, Clinica Medellin , Medellin , Colombia.
authors.forename: Lina M
authors.initials: LM
authors.lastname: Restrepo
authors.affiliation: Laboratorio de Patologia y Citologia Rodrigo Restrepo, Department of Pathology, Clinica Medellin , Medellin , Colombia.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Serna
authors.affiliation: Laboratory Medicine, Division of Pathology, St. Michael's Hospital, University of Toronto , Toronto, ON , Canada.
authors.forename: Kalman
authors.initials: K
authors.lastname: Kovacs
keywords: Carney complex; acromegaly; diagnosis; familial isolated; genetics; multiple endocrine neoplasia type 1; pathology; pituitary adenoma