title: Improved detectability of microcirculatory dynamics by laser speckle flowmetry.
abstract: Mechanisms of renal autoregulation generate oscillations in arterial blood flow at several characteristic frequencies. Full-field laser speckle flowmetry provides a real-time imaging of superficial blood microcirculation. The possibility to detect changes in oscillatory dynamics is an important issue in biomedical applications. In this paper we show how laser power density affects quality of the recorded signal and improves detectability of temporal changes in microvascular perfusion.
authors.affiliation: Department of Biomedical Sciences, Copenhagen University, Blegdamsvej 3, 2200, Copenhagen, Denmark. dpostnov@sund.ku.dk.
authors.forename: Dmitry D
authors.initials: DD
authors.lastname: Postnov
authors.affiliation: Department of Biomedical Sciences, Copenhagen University, Blegdamsvej 3, 2200, Copenhagen, Denmark.
authors.forename: Olga
authors.initials: O
authors.lastname: Sosnovtseva
authors.affiliation: Research-Educational Institute of Optics and Biophotonics, Saratov State University, Astrakhanskaya Str. 83, 410012, Saratov, Russia.|Institute of Precision Mechanics and Control RAS, Rabochaya str. 24, 410028, Saratov, Russia.|Interdisciplinary Laboratory of Biophotonics, National Research Tomsk State University, 634050, Tomsk, Russia.
authors.forename: Valery V
authors.initials: VV
authors.lastname: Tuchin
mesh_terms: D000818:Animals; D006801:Humans; D007668:Kidney / Q000098:blood supply; D007834:Lasers; D008833:Microcirculation / Q000528:radiation effects; D019047:Phantoms, Imaging; D051381:Rats; D017207:Rats, Sprague-Dawley; D012212:Rheology / Q000379:methods*
keywords: dynamics; kidney; laser speckle flowmetry; microcirculation