title: [Comparison of FRAX Score without bone mineral density determination and the criteria proposed by the Argentine Osteoporosis Society for the use of antiresorptive therapy in postmenopausal women].
abstract: To identify patients at high risk of fracture using clinical risk factors could reduce health costs arising from the realization of a bone densitometry. The aim of this study was to compare the FRAX score without bone mineral density (BMD) with the criteria proposed by the Argentine Society of Osteoporosis (SAO) to consider starting antiresorptive treatment. We conducted an observational, cross-sectional study where 330 postmenopausal women between 40 and 90 years of age were included. The number of treatments given if the FRAX tool without BMD had been followed was compared with the number of treatments indicated using the SAO criteria. Using the SAO criteria, 85 (25.8%) patients would initiate antiresorptive treatment compared with 15 (4.5%) using the FRAX without BMD (p = 0.0019). Among the 67 patients with a diagnosis of osteoporosis by BMD determination, all of them (100%) would have received treatment by using the SAO criteria compared with 10 (15%) using the FRAX score (p = 0.011). The use of FRAX without BMD significantly underestimates the number of patients who should receive antiresorptive treatment. In patients diagnosed with osteoporosis by BMD, the FRAX score underestimates the number of patients to be treated.
authors.affiliation: Servicio de Clínica Médica, Clínica Universitaria Reina Fabiola, Córdoba, Argentina. E-mail: fercam02@hotmail.com.
authors.forename: Fernando
authors.initials: F
authors.lastname: Camporro
authors.forename: Laura
authors.initials: L
authors.lastname: Redondo
authors.forename: Exequiel
authors.initials: E
authors.lastname: Bulacio
authors.forename: Ignacio
authors.initials: I
authors.lastname: Gutiérrez Magaldi
authors.forename: Elías
authors.initials: E
authors.lastname: Chamale
authors.forename: Fabián
authors.initials: F
authors.lastname: Sáenz
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001118:Argentina; D015519:Bone Density; D003430:Cross-Sectional Studies; D005260:Female; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000000981:diagnostic imaging / Q000209:etiology / Q000517:prevention & control*; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012955:Societies, Medical
keywords: FRAX score; antiresorptive treatment; osteoporosis; risk of fracture