title: Treatment Paradigm After Uncomplicated Cataract Surgery: A Prospective Evaluation.
abstract: OBJECTIVE
  To compare 3 clinical variables, namely, visual recovery, anterior chamber inflammation, and macular edema, between 2 different regimens after uncomplicated cataract surgery.
  
  
  METHODS
  Prospective, randomized, single-blind study at a single center, private, teaching practice in Las Vegas, NV.
  
  
  METHODS
  Patients randomized to group I (nonsteroidal anti-inflammatory drugs, n = 113) received besifloxacin ophthalmic suspension 0.6% and bromfenac 0.09%, whereas those randomized to group II (steroid, n = 109) received besifloxacin ophthalmic suspension 0.6% and prednisolone acetate 1%.Preoperative evaluation included a baseline macular optical coherence tomography. Postoperative data collected included visual acuity, direct visual anterior segment cell and flare counts, and macular optical coherence tomographies. Foveal thickness and total macular volume were used to assess the presence of cystoid macular edema.
  
  
  RESULTS
  Visual recovery was statistically insignificant with P values at 0.7, 0.10, 0.2, and 0.7 at 1 day, 1 week, 1 month, and 2 months, respectively.The degree of anterior segment inflammation was not statistically significant (P = 0.8) between the studied populations.The foveal thickness (1 week, P = 0.8; 1 month, P = 0.2; 2 months, P = 0.2) and total macular volume (1 week, P = 0.7; 1 month, P = 0.1; 2 months, P = 0.2) were not statistically significant between the groups, and the observed power were 0.902 and 0.666, respectively.
  
  
  CONCLUSIONS
  This study demonstrated that bromfenac was equally efficacious when compared with a potent topical steroid in restoring visual function, decreasing and resolving anterior chamber inflammation, and preventing the development of macular edema.
authors.affiliation: From the *Westfield Eye Center, Las Vegas; and †Nevada State College, Henderson, NV.
authors.forename: Hon-Vu Q
authors.initials: HV
authors.lastname: Duong
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Westfield
authors.forename: Isaac C
authors.initials: IC
authors.lastname: Singleton