title: BlastXtract2: Improving early exploration of (meta) genomes.
abstract: To manage and intelligently mine the avalanche of genomic sequences intuitive and user-friendly graphical interfaces are required. Here we present BlastXtract2 which exclusively facilitates early exploration of un-annotated genomic and metagenomic sequences. Various formats of translated searches, including the commonly used BlastX, of multiple sequences against multiple protein databases can be uploaded to a relational database server, which can be accessed via a locally installed web-server. There, an intuitive GUI allows straightforward data-mining and enables quick detection of potential frameshifts and poorly sequenced or assembled regions, thereby contributing in making BlastXtract2 a unique and valuable tool for early exploration of (meta)genomic sequences.
  
  
  BACKGROUND
  Source code, documentation and an online demo version are available at https://github.com/ ClaessonLab/BlastXtract2.
authors.affiliation: Microbiology and Systems Biology, TNO, Zeist, The Netherlands.
authors.forename: Heleen
authors.initials: H
authors.lastname: de Weerd
authors.affiliation: Genomics Core Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
authors.forename: Bernd E
authors.initials: BE
authors.lastname: van der Veen
authors.affiliation: School of microbiology and alimentary pharmabiotic centre, university college cork, cork, Ireland.
authors.forename: Marcus J
authors.initials: MJ
authors.lastname: Claesson