title: EFFECTS OF DEXAMETHASONE AND PHENIRAMINE MALEATE ON HEMODYNAMIC AND RESPIRATORY PARAMETERS AFTER CEMENTATION IN CEMENTED PARTIAL HIP PROSTHESIS.
abstract: OBJECTIVE
  To prevent hemodynamic and respiratory changes that are likely to occur during cementation in partial hip prosthesis by prophylactic use of pheniramine maleate and dexamethasone.
  
  
  METHODS
  The study included 40 patients aged between 60 and 85 years with an American Society ofAnesthesiologists (ASA) grade of II-III who underwent partial hip prosthesis. Just after spinal anesthesia, 4 mL normal saline was pushed in patients in Group S, whereas 45.5 mg pheniramine maleate and 8 mg dexamethasone mixture was pushed intravenously in a total volume of 4 mL in patients in Group PD.
  
  
  RESULTS
  Amounts of atropine and adrenaline administered after cementation were significantly higher in Group S than in Group PD (P < 0.05). There was a significant difference between SpO2 values before and after cementation in Group S; SpO2 value was lower after cementation (P < 0.05) except for 1. min after cementation. SpO2 value increased 1 min after cementation (P = 0.031) CONCLUSION: Prophylactic use of pheniramine maleate and dexamethasone in partial hip prosthesis led to an increase in SpO2 value and a decrease in the utilization of adrenaline and atropine after cementation.
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: Yektaş
authors.forename: Funda
authors.initials: F
authors.lastname: Gümüş
authors.forename: Tolga
authors.initials: T
authors.lastname: Totoz
authors.forename: Nurten
authors.initials: N
authors.lastname: Gül
authors.forename: Kerem
authors.initials: K
authors.lastname: Erkalp
authors.forename: Ayşin
authors.initials: A
authors.lastname: Alagöl
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D002484:Cementation; D003907:Dexamethasone / Q000494:pharmacology*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010632:Pheniramine / Q000494:pharmacology*; D012119:Respiration / Q000187:drug effects*
chemical_list: D010632:Pheniramine; D003907:Dexamethasone; D010100:Oxygen