title: Current applications of biomarkers in cardiomyopathies.
abstract: Cardiomyopathies are an important cause of sudden cardiac death in young people and are responsible for arrhythmias and premature heart failure in all age groups. Although many cardiomyopathies are inherited, biochemical markers are a fundamental part of the diagnostic work-up and are useful in the prognostic assessment of disease. In this article, the authors review the rationale and evidence for important biomarkers according to their role in patient management. Emerging biomarkers are briefly reviewed, alongside modern scientific approaches to biomarker discovery.
authors.affiliation: Institute of Cardiovascular Science, The Heart Hospital, 16-18 Westmoreland Street, London W1G 8PH, UK.
authors.forename: Caroline J
authors.initials: CJ
authors.lastname: Coats
authors.forename: Wendy E
authors.initials: WE
authors.lastname: Heywood
authors.forename: Kevin
authors.initials: K
authors.lastname: Mills
authors.forename: Perry M
authors.initials: PM
authors.lastname: Elliott
mesh_terms: D015415:Biomarkers / Q000032:analysis; D009202:Cardiomyopathies / Q000097:blood / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D012307:Risk Factors
chemical_list: D015415:Biomarkers
keywords: biomarkers; cardiomyopathy; myocardial; natriuretic peptides; troponin