title: Intestinal Pseudoobstruction Caused by Chronic Lyme Neuroborreliosis. A Case Report.
abstract: Chronic intestinal pseudoobstruction is often classified as idiopathic. The condition is associated with poor quality of life and high morbidity, and treatment options are often unsatisfactory. A case of chronic intestinal pseudoobstruction in a 66-year-old woman, presenting with back and abdominal pain, urinary retention and severe constipation is described. The patient lived in an area in which Lyme disease is endemic and had been bitten by ixodes ticks. Intrathecal synthesis of anti-borrelia IgM and IgG and lymphocytosis in the cerebrospinal fluid was found, consistent with chronic Lyme neuroborreliosis since symptoms had lasted for more than six months. The patient's gastrointestinal function recovered and the pain subsided significantly following treatment with antibiotics. Lyme neuroborreliosis (LNB) often results in palsy, but rarely affects the autonomic nervous system. Three patients have been described with intestinal pseudoobstruction due to acute LNB. However, this is the first described case of intestinal pseudoobstruction due to chronic Lyme neuroborreliosis. LNB must be suspected in patients with intestinal pseudoobstruction, in particular in patients who have been bitten by an ixodes tick and in patients living in an endemic area.
authors.affiliation: Department of Gastrointestinal Surgery, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
authors.forename: David F
authors.identifier: http://orcid.org/0000-0002-6532-9259
authors.initials: DF
authors.lastname: Schefte
authors.affiliation: Department of Gastrointestinal Surgery, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
authors.forename: Tyge
authors.initials: T
authors.lastname: Nordentoft
keywords: Constipation; Intestinal pseudoobstruction; Lyme neuroborreliosis