title: Tissue-Engineered Autologous Breast Regeneration with Brava®-Assisted Fat Grafting.
abstract: A technique of whole and partial breast reconstruction is described based on tissue-engineering principles. Brava-assisted external tissue expansion generates an in situ biological recipient scaffold that favors the survival of large volumes of autologous fat graft required for breast reconstruction. Also presented are the results of the authors' multicenter experience with this regenerative alternative in 488 patients over a 7-year period tracking surgical complications, patient satisfaction, efficacy, and costs.
authors.affiliation: Miami Breast Center, Key Biscayne, FL, USA. Electronic address: tkosowski@gmail.com.
authors.forename: Tomasz R
authors.initials: TR
authors.lastname: Kosowski
authors.affiliation: Clinica San Clemente, Mantava, Italy.
authors.forename: Gino
authors.initials: G
authors.lastname: Rigotti
authors.affiliation: Miami Breast Center, Key Biscayne, FL, USA.
authors.forename: Roger K
authors.initials: RK
authors.lastname: Khouri
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D001940:Breast / Q000502:physiology / Q000601:surgery*; D001943:Breast Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D015187:Lipectomy; D016462:Mammaplasty / Q000295:instrumentation / Q000379:methods*; D008408:Mastectomy; D012038:Regeneration; D023822:Tissue Engineering; D015626:Tissue Expansion / Q000295:instrumentation; D054457:Tissue Scaffolds; D016378:Tissue Transplantation; D020858:Tissue and Organ Harvesting; D014182:Transplantation, Autologous
keywords: Autologous fat transfer; Biological scaffold; Brava; Brava + AFT; Breast reconstruction; Fat grafting; Tissue engineering; Tissue expansion