title: Is omitting the 3rd hour measurement in the 100 g oral glucose tolerance test feasible?
abstract: BACKGROUND
  To evaluate the diagnostic value of the 3rd hour plasma glucose level in the 100 g oral glucose tolerance test (OGTT).
  
  
  METHODS
  Records of all pregnant patients with abnormal 50 g glucose challenge test (GCT) between January 2005 and December 2013 were reviewed (n=1963). The 100 g OGTT results were analyzed separately for both Carpenter & Couston (CC) and National Diabetes Data Group (NDDG) criteria.
  
  
  RESULTS
  The number of patients diagnosed with gestational diabetes mellitus (GDM) was 297 (15.1%) according to CC criteria and 166 (8.4%) according to NDDG criteria. The 1st hour plasma glucose level showed the highest correlation with GDM diagnosis (ρ=0.595 for CC and ρ=0.567 for NDDG). However, the 3rd hour plasma glucose level showed the weakest correlation with GDM diagnosis (ρ=0.216 for CC and ρ=0.213 for NDDG). The 3rd hour value of 100 g OGTT was one of the two elevated measurements in 10.8% of patients when CC criteria are used and in 13.8% of patients when NDDG criteria are used.
  
  
  CONCLUSIONS
  Omitting 3rd hour plasma glucose measurement in 100 g OGTT results in unacceptable rates of underdiagnosed patients.
authors.forename: Yavuz Emre
authors.initials: YE
authors.lastname: Şükür
authors.forename: Mehmet Murat
authors.initials: MM
authors.lastname: Seval
authors.forename: Batuhan
authors.initials: B
authors.lastname: Özmen
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Yalçin
authors.forename: Zihni
authors.initials: Z
authors.lastname: Karaeren
authors.forename: Feride
authors.initials: F
authors.lastname: Söylemez
authors.forename: Acar
authors.initials: A
authors.lastname: Koç
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D015331:Cohort Studies; D016640:Diabetes, Gestational / Q000097:blood / Q000175:diagnosis*; D003951:Diagnostic Errors; D005240:Feasibility Studies; D005260:Female; D005951:Glucose Tolerance Test / Q000379:methods*; D006801:Humans; D011247:Pregnancy; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D001786:Blood Glucose