title: [LYMPHOCYTES MEMBRANES FATTY ACID SPECTRUM IN PATIENTS WITH CORONARY HEART DISEASE].
abstract: Lymphocytes phospholipid membranes fatty acid spectrum was studied in patients with coronary heart disease. The study involved 77 patients aged 45 to 72 years. Significant decrease of the oleic fatty acid relative content was determined, which violates the lymphocytes membranes structure and possibly negatively affect their functioning. The relative content of arachidonic, palmitic and stearic saturated fatty acids composition of lymphocytes lipids increased. The result indicate that in patients with coronary heart disease increasing polyunsaturated fatty acids elongation in lymphocytes. These changes in the lipid blood, lymphocytes state can explain the observed increase in lymphocytes functional activity.
authors.forename: T V
authors.initials: TV
authors.lastname: Zaval's'ka
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D002462:Cell Membrane / Q000378:metabolism*; D005227:Fatty Acids / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000378:metabolism*; D010743:Phospholipids / Q000737:chemistry* / Q000378:metabolism
chemical_list: D005227:Fatty Acids; D010743:Phospholipids