title: Is the "I-Sign" in the 3-Vessel and Trachea View a Valid Tool for Prenatal Diagnosis of D-Transposition of the Great Arteries?
abstract: Prenatal diagnosis of D-transposition of the great arteries remains less frequent compared to other major congenital heart defects. In this study, we examined how often the 3-vessel and trachea view was abnormal in a large series of prenatally diagnosed cases of D-transposition of the great arteries. We found that an abnormal 3-vessel and trachea view in the shape of an "I" ("I-sign"), which represents an anteriorly displaced aorta, was present in all fetuses with D-transposition of the great arteries when a 3-vessel and trachea view was successfully obtained. Therefore we believe that the 3-vessel and trachea view can be used to reliably detect D-transposition of the great arteries during prenatal sonography.
authors.affiliation: Departments of Obstetrics and Gynecology (A.P., W.A.G., L.S.C.) and Pediatrics (N.L.G.), Northwestern University, Feinberg School of Medicine, Chicago, Illinois USA. anna.palatnik@northwestern.edu.
authors.forename: Anna
authors.initials: A
authors.lastname: Palatnik
authors.affiliation: Departments of Obstetrics and Gynecology (A.P., W.A.G., L.S.C.) and Pediatrics (N.L.G.), Northwestern University, Feinberg School of Medicine, Chicago, Illinois USA.
authors.forename: Nina L
authors.initials: NL
authors.lastname: Gotteiner
authors.affiliation: Departments of Obstetrics and Gynecology (A.P., W.A.G., L.S.C.) and Pediatrics (N.L.G.), Northwestern University, Feinberg School of Medicine, Chicago, Illinois USA.
authors.forename: William A
authors.initials: WA
authors.lastname: Grobman
authors.affiliation: Departments of Obstetrics and Gynecology (A.P., W.A.G., L.S.C.) and Pediatrics (N.L.G.), Northwestern University, Feinberg School of Medicine, Chicago, Illinois USA.
authors.forename: Leeber S
authors.initials: LS
authors.lastname: Cohen
mesh_terms: D005260:Female; D005318:Fetal Heart / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D011247:Pregnancy; D015203:Reproducibility of Results; D014132:Trachea / Q000000981:diagnostic imaging*; D014188:Transposition of Great Vessels / Q000000981:diagnostic imaging*; D016216:Ultrasonography, Prenatal / Q000706:statistics & numerical data*
keywords: 3-vessel and trachea view; d-transposition of the great arteries; obstetric ultrasound; prenatal diagnosis