title: Syntheses, crystallographic, mass-spectroscopic determination and antioxidant studies of Co(II), Ni(II) and Cu(II) complexes of a new imidazol based Schiff base.
abstract: A new imidazole-based Schiff base, 2-((1H-imidazol-4-yl)methyleneamino)benzylalcohol (HL) and corresponding analogous bis(2-((1H-imidazol-4-yl)methyleneimino)benzylalcohol)metal(II) perchlorates (M: Co(1), Ni(2), Cu(3)) have prepared and characterized by elemental analyses, ESI-MS, IR, UV-Vis spectroscopies and conductivity measurements. X-ray single crystal structures of 1 and 2 have been also determined. Elemental analyses, spectroscopic and conductance data of 3 demonstrated similar structural features with these of crystallographically characterized complexes and based upon this relevances, HL ligands are neutrally coordinated to metal(II) ions in tridentate mode and all complexes are isostructural, dicathionic, contain perchlorate anions as complementary ions and, are in octahedral geometry with the formulae of [M(HL)2](ClO4)2 (for 3) and [M(HL)2](ClO4)2·H2O (for 1 and 2). Radical scavenging activities of the complexes have been evaluated by using DPPH, DMPD(+), and ABTS(+) assays. SC50 values (μg/mL) of the complexes and standards on DPPH, DMPD(+), ABTS(+) follow the sequences, BHA (9.06±0.33)>CMPD3 (15.62±0.52)>CMPD2 (17.43±0.29)>Rutin (21.65±0.60)>CMPD1 (25.67±0.51)>Trolox (28.57±0.37), Rutin>BHA>CMPD3>CMPD2>Trolox>CMPD1, and Trolox>BHA>CMPD3>CMPD2>Rutin>CMPD1 respectively.
authors.affiliation: Department of Industrial Engineering, Faculty of Engineering, Giresun University, Giresun, Turkey. Electronic address: serkand@omu.edu.tr.
authors.forename: Serkan
authors.initials: S
authors.lastname: Demir
authors.affiliation: Vocational High School of Health Services, Department of Medical Services and Techniques, Giresun University, Giresun, Turkey.
authors.forename: Aytaç
authors.initials: A
authors.lastname: Güder
authors.affiliation: Department of Chemical Engineering, Faculty of Engineering, Ondokuz Mayis University, 55200 Atakum, Samsun, Turkey.
authors.forename: Turan K
authors.initials: TK
authors.lastname: Yazıcılar
authors.affiliation: Department of Chemistry, Faculty of Arts and Sciences, Erzincan University, Erzincan, Turkey.
authors.forename: Sema
authors.initials: S
authors.lastname: Çağlar
authors.affiliation: Department of Physics, Faculty of Arts and Sciences, Ondokuz Mayis University, 55200 Atakum, Samsun, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Büyükgüngör
mesh_terms: D003035:Cobalt / Q000737:chemistry / Q000494:pharmacology; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D003300:Copper / Q000737:chemistry / Q000494:pharmacology; D018360:Crystallography, X-Ray; D016166:Free Radical Scavengers / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D008958:Models, Molecular; D009532:Nickel / Q000737:chemistry / Q000494:pharmacology; D012545:Schiff Bases / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D056831:Coordination Complexes; D016166:Free Radical Scavengers; D007093:Imidazoles; D012545:Schiff Bases; D003035:Cobalt; D003300:Copper; C029899:imidazole; D009532:Nickel
keywords: Crystal structure; ESI-MS; Imidazole-based-Schiff base; Radical scavenging activity; Schiff base-metal(II) complex