title: Seizures in sleep: clinical spectrum, diagnostic features, and management.
abstract: Sleep is disrupted in most patients hospitalized in the intensive care unit and the disturbances are even more profound in patients impacted by epilepsy. Nocturnal seizures must be differentiated from other common nocturnal events, such as delirium, parasomnias, and sedation. Many antiepileptic drugs produce undesirable side effects on sleep architecture that may further predispose patients to insomnia during the night and excessive sedation and hypersomnolence during the day. Failure to recognize, correctly diagnose, and adequately manage these disturbances may lead to more prolonged hospitalization, increased risk for nosocomial infections, poorer health-related qualify of life, and greater health care financial burden.
authors.affiliation: UCLA, Department of Neurology, UCLA Seizure Disorders Center, David Geffen School of Medicine at UCLA, 710 Westwood Boulevard, Room 1-250, RNRC, Los Angeles, CA 90095-1769, USA.
authors.forename: Dawn
authors.initials: D
authors.lastname: Eliashiv
authors.affiliation: UCLA, Department of Neurology, UCLA Neurology Clinic, UCLA Sleep Disorders Center, David Geffen School of Medicine at UCLA, 710 Westwood Boulevard, Room 1-145, RNRC, Los Angeles, CA 90095-1769, USA. Electronic address: avidan@mednet.ucla.edu.
authors.forename: Alon Y
authors.initials: AY
authors.lastname: Avidan
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007362:Intensive Care Units; D020447:Parasomnias / Q000175:diagnosis; D012640:Seizures / Q000188:drug therapy*; D012890:Sleep / Q000502:physiology*; D020181:Sleep Apnea, Obstructive / Q000139:chemically induced; D012893:Sleep Wake Disorders / Q000139:chemically induced*
chemical_list: D000927:Anticonvulsants
keywords: Antiepileptic drugs; Epilepsy; Epilepsy syndrome; Seizures