title: Theranostic Imaging of Yttrium-90.
abstract: This paper overviews Yttrium-90 ((90)Y) as a theranostic and nuclear medicine imaging of (90)Y radioactivity with bremsstrahlung imaging and positron emission tomography. In addition, detection and optical imaging of (90)Y radioactivity using Cerenkov luminescence will also be reviewed. Methods and approaches for qualitative and quantitative (90)Y imaging will be briefly discussed. Although challenges remain for (90)Y imaging, continued clinical demand for predictive imaging response assessment and target/nontarget dosimetry will drive research and technical innovation to provide greater clinical utility of (90)Y as a theranostic agent.
authors.affiliation: Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors.forename: Chadwick L
authors.initials: CL
authors.lastname: Wright
authors.affiliation: Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors.forename: Michael F
authors.initials: MF
authors.lastname: Tweedle
authors.affiliation: Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
authors.forename: Michael V
authors.initials: MV
authors.lastname: Knopp
authors.affiliation: Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Nathan C
authors.initials: NC
authors.lastname: Hall
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D011874:Radiometry; D019275:Radiopharmaceuticals / Q000737:chemistry / Q000627:therapeutic use*; D000068936:Theranostic Nanomedicine; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed; D015021:Yttrium Radioisotopes / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D019275:Radiopharmaceuticals; D015021:Yttrium Radioisotopes