title: Cushing's syndrome presenting as treatment-resistant bipolar affective disorder: A step in understanding endocrine etiology of mood disorders.
abstract: Cushing's syndrome (CS) is the multisystem disorder which is due to cortisol excess. It is very difficult to diagnose in early stages, especially when psychiatric manifestations are the predominant complaints. It could result in significant morbidity and mortality. We report a case of resistant bipolar affective disorder secondary to CS. Early diagnosis and treatment will lead to better functional outcome and prevention of neurocognitive side-effects of excessive cortisol.
authors.affiliation: Department of Psychiatry, PSGIMSR, Coimbatore, Tamil Nadu, India.
authors.forename: I Syed
authors.initials: IS
authors.lastname: Ummar
authors.affiliation: Department of Psychiatry, MMCHRI, Kanchipuram, Tamil Nadu, India.
authors.forename: Venkateswaran
authors.initials: V
authors.lastname: Rajaraman
authors.affiliation: Department of Pulmonology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: N
authors.initials: N
authors.lastname: Loganathan
keywords: Bipolar disorder; Cushing's syndrome; treatment resistance