title: Rubicon swaps autophagy for LAP.
abstract: Phagocytic cells engulf their prey into vesicular structures called phagosomes, of which a certain proportion becomes demarcated for enhanced maturation by a process called LC3-associated phagocytosis (LAP). Light has now been shed on the molecular requirements of LAP, establishing a central role for the protein Rubicon in the immune response to Aspergillus fumigatus.
authors.affiliation: MRC Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
authors.forename: Keith B
authors.initials: KB
authors.lastname: Boyle
authors.affiliation: 1] MRC Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Francis Crick Avenue, Cambridge, CB2 0QH, UK [2] Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
authors.forename: Felix
authors.initials: F
authors.lastname: Randow
mesh_terms: D000818:Animals; D001343:Autophagy; D005260:Female; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D008297:Male; D008562:Membrane Glycoproteins / Q000378:metabolism*; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D019255:NADPH Oxidases / Q000378:metabolism*; D010587:Phagocytosis
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D008562:Membrane Glycoproteins; D008869:Microtubule-Associated Proteins; D019255:NADPH Oxidases