title: Volumetric relief map for intracranial cerebrospinal fluid distribution analysis.
abstract: Cerebrospinal fluid imaging plays a significant role in the clinical diagnosis of brain disorders, such as hydrocephalus and Alzheimer's disease. While three-dimensional images of cerebrospinal fluid are very detailed, the complex structures they contain can be time-consuming and laborious to interpret. This paper presents a simple technique that represents the intracranial cerebrospinal fluid distribution as a two-dimensional image in such a way that the total fluid volume is preserved. We call this a volumetric relief map, and show its effectiveness in a characterization and analysis of fluid distributions and networks in hydrocephalus patients and healthy adults.
authors.affiliation: GREYC, UMR CNRS 6072 - ENSICAEN & Université de Caen, F-14050 Caen, France. Electronic address: alain.rene.lebret@gmail.com.
authors.forename: Alain
authors.initials: A
authors.lastname: Lebret
authors.affiliation: Université Paris-Est, LIGM, UMR CNRS 8049, UPEM, F-77454 Marne-la-Vallée, France.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Kenmochi
authors.affiliation: Hôpital Saint-Joseph, F-75014 Paris, France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Hodel
authors.affiliation: AP-HP, Hôpital H. Mondor, F-94000 Créteil, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Rahmouni
authors.affiliation: AP-HP, Hôpital Beaujon, F-92110 Clichy, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Decq
authors.affiliation: Université Paris-Est, LISSI (EA 3956), UPEC, F-94010 Créteil, France.
authors.forename: Éric
authors.initials: É
authors.lastname: Petit
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001921:Brain / Q000473:pathology*; D002555:Cerebrospinal Fluid / Q000166:cytology*; D006801:Humans; D006849:Hydrocephalus / Q000134:cerebrospinal fluid* / Q000473:pathology*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D015203:Reproducibility of Results; D012212:Rheology / Q000379:methods; D012680:Sensitivity and Specificity; D055815:Young Adult
keywords: Cerebrospinal fluid; Computer-aided diagnosis; Cortical subarachnoid space; Hydrocephalus; Volume preserving; Volumetric relief map