title: Pancreatic mucinous cystic neoplasm in a transgender patient.
abstract: BACKGROUND
  Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females.
  
  
  METHODS
  Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy.
  
  
  CONCLUSIONS
  To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA.
authors.forename: Deshka
authors.initials: D
authors.lastname: Foster
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA.
authors.forename: Mohammad F
authors.initials: MF
authors.lastname: Shaikh
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Gleeson
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA.
authors.forename: Blake D
authors.initials: BD
authors.lastname: Babcock
authors.affiliation: Department of Pathology, Drexel University College of Medicine, 254 N. 15th St, MS 435, Philadelphia, PA, 19102, USA.
authors.forename: Jianping
authors.initials: J
authors.lastname: Lin
authors.affiliation: Department of Pathology, Drexel University College of Medicine, 254 N. 15th St, MS 435, Philadelphia, PA, 19102, USA.
authors.forename: Robert T
authors.initials: RT
authors.lastname: Ownbey
authors.affiliation: Department of Diagnostic Radiology, Hahnemann University Hospital, 230 N. 15th St, MS 206, Philadelphia, PA, 19102, USA.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Hysell
authors.affiliation: Department of Medicine, Drexel University College of Medicine, 254 N. 15th St, MS 427, Philadelphia, PA, 19102, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Ringold
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, 254 N. 15th St, MS 413, Philadelphia, PA, 19102, USA. wilbur.bowne@drexelmed.edu.
authors.forename: Wilbur B
authors.initials: WB
authors.lastname: Bowne
mesh_terms: D000328:Adult; D018291:Cystadenoma, Mucinous / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D063106:Transgender Persons