title: Evaluation of the 'Prostate Interdisciplinary Communication and Mapping Algorithm for Biopsy and Pathology' (PIC-MABP).
abstract: BACKGROUND
  Experience from interdisciplinary cooperation revealed the need for a prostate mapping scheme to communicate multiparametric MRI (mpMRI) findings between radiologists, urologists, and pathologists, which should be detailed, yet easy to memorize. For this purpose, the 'Prostate interdisciplinary communication and mapping algorithm for biopsy and pathology' (PIC-MABP) was developed. This study evaluated the accuracy of the PIC-MABP system.
  
  
  METHODS
  PIC-MABP was tested and validated in findings of 10 randomly selected patients from routine clinical practise with 18 histologically proven cancer lesions. Patients received an mpMRI of the prostate prior to prostatectomy. After surgery the prostates were prepared as whole-mount step sections. Cancer lesions, which were found suspicious on mpMRI, were assigned to the according PIC-MABP sectors by a radiologist. MpMRI slides were masked and sent to seven urologists from different centres, providing only the PIC-MABP location of each lesion. Urologists marked the accordant regions. Then mpMRI slides were unmasked, and the correctness of each mark was evaluated.
  
  
  RESULTS
  One hundred and seventeen of the 126 marks (93%) were correctly assigned. Detection rates differed for lesions >0.5 cc compared with lesions <0.5 cc (p < 0.005): 3/7 (43%) marks were correctly assigned in lesions <0.3 cc, 16/21 (76%) in lesions with 0.3-0.5 cc, and 98/98 (100%) in lesions >0.5 cc. Interobserver agreement was good for lesions >0.5 cc and poor for lesions <0.3 cc (Fleiss Kappa 1 vs. 0.0175).
  
  
  CONCLUSIONS
  PIC-MABP seems to be a reliable system to communicate the location of mpMRI findings >0.5 cc between different disciplines and can be a useful guidance for cognitive mpMRI/TRUS fusion biopsy.
authors.affiliation: Department of Radiology, Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria. junkerda@gmail.com.
authors.forename: Daniel
authors.initials: D
authors.lastname: Junker
authors.affiliation: Department of Urology and Urooncology, Hanover Medical School [MHH], Carl Neuberg Str. 1, 30625, Hannover, Germany. Herrmann.Thomas@mh-hannover.de.
authors.forename: Thomas R W
authors.initials: TR
authors.lastname: Herrmann
authors.affiliation: UroClinic München Giesing, Tegernseer Landstraße 44a, 81541, Munich, Germany. markus.bader@urologie-giesing.de.
authors.forename: Markus
authors.initials: M
authors.lastname: Bader
authors.affiliation: Department of Urology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. Jasmin.bektic@i-med.ac.at.
authors.forename: Jasmin
authors.initials: J
authors.lastname: Bektic
authors.affiliation: Urologic Practice Dr. Gregor Henkel, Prof. Sinwel Weg 4/2, 6330, Kufstein, Austria. gregor.henkel@kufnet.at.
authors.forename: Gregor
authors.initials: G
authors.lastname: Henkel
authors.affiliation: University Hospital for Urology Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany. stephan.kruck@gmail.com.
authors.forename: Stephan
authors.initials: S
authors.lastname: Kruck
authors.affiliation: Urologic Practice Dr. Sandbichler, Speckbacherstraße 20, 6380, St. Johann in Tirol, Austria. office@urologie-sandbichler.at.
authors.forename: Markus
authors.initials: M
authors.lastname: Sandbichler
authors.affiliation: University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt Am Main, Germany. schilling_david@hotmail.com.
authors.forename: David
authors.initials: D
authors.lastname: Schilling
authors.affiliation: Department of Pathology, Medical University Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria. Georg.schaefer@i-med.ac.at.
authors.forename: Georg
authors.initials: G
authors.lastname: Schäfer
authors.affiliation: Landeskrankenhaus Hall, Abteilung für Urologie und Andrologie, Milser Straße 10, 6060, Hall in Tirol, Austria. udo.nagele@tilak.at.
authors.forename: Udo
authors.initials: U
authors.lastname: Nagele
mesh_terms: D000368:Aged; D000465:Algorithms; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D033183:Interdisciplinary Communication; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods*; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D015203:Reproducibility of Results
keywords: Multiparametric magnetic resonance imaging; PIC-MABP; Prostate cancer; Prostate mapping algorithm; Prostate reporting scheme