title: Vulvar Intraepithelial Neoplasia (VIN) and Condylomata.
abstract: Human papillomavirus (HPV) infection of the lower genital tract is common and its effects are variable. The majority of infections are transient and the related pathology is self-resolving. Condyloma accuminatum is caused predominantly by HPV 6, 11 and can be managed with medical or surgical therapy. Vulvar intraepithelial neoplasia is a treatable precursor to vulvar cancer with 2 main forms: one related to HPV and the other to chronic vulvar inflammatory conditions. It may be treated medically, surgically, or potentially via the use of therapeutic HPV vaccines. Preventive utilization of a quadrivalent HPV vaccine has the potential to decrease HPV-related lower genital disease burden substantially.
authors.affiliation: *Colposcopy Services, Department of Obstetrics and Gynecology, University of Texas School of Medicine San Antonio, San Antonio, Texas †Department of Obstetrics and Gynecology, University of Torino, Torino, Italy ‡Department of Obstetrics and Gynecology, The University of Iowa, Iowa City, Iowa.
authors.forename: Erin L
authors.initials: EL
authors.lastname: Nelson
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Bogliatto
authors.forename: Colleen K
authors.initials: CK
authors.lastname: Stockdale
mesh_terms: D002278:Carcinoma in Situ / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D003218:Condylomata Acuminata / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D006801:Humans; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D053918:Papillomavirus Vaccines / Q000627:therapeutic use; D011230:Precancerous Conditions / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D014846:Vulvar Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy
chemical_list: D053918:Papillomavirus Vaccines