title: Strong inhibition of betanodavirus replication by ribavirin targeting RNA-dependent RNA polymerase.
authors.affiliation: Institute of Fisheries Science, College of Life Science, National Taiwan University, Taipei, Taiwan.
authors.forename: Y-C
authors.identifier: http://orcid.org/0000-0002-4076-1360
authors.initials: YC
authors.lastname: Huang
authors.affiliation: Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.|Institute of Biochemistry, College of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
authors.forename: T-S
authors.initials: TS
authors.lastname: Lin
authors.affiliation: Taiwan Leading Biotech Inc., Taipei, Taiwan.
authors.forename: C
authors.initials: C
authors.lastname: Peng
authors.affiliation: Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.|Institute of Biochemistry, College of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
authors.forename: N-L
authors.initials: NL
authors.lastname: Chan
authors.affiliation: Institute of Fisheries Science, College of Life Science, National Taiwan University, Taipei, Taiwan.|Department of Life Science, College of Life Science, National Taiwan University, Taipei, Taiwan.
authors.forename: Y-S
authors.initials: YS
authors.lastname: Han
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001492:Bass / Q000821:virology; D002460:Cell Line; D005393:Fish Diseases / Q000821:virology*; D008958:Models, Molecular; D030381:Nodaviridae / Q000187:drug effects* / Q000201:enzymology / Q000502:physiology; D017434:Protein Structure, Tertiary; D012327:RNA Virus Infections / Q000821:virology*; D012324:RNA-Dependent RNA Polymerase / Q000378:metabolism*; D012254:Ribavirin / Q000494:pharmacology*; D016415:Sequence Alignment; D014779:Virus Replication / Q000187:drug effects*
chemical_list: D012254:Ribavirin; D012324:RNA-Dependent RNA Polymerase
keywords: RNA-dependent RNA polymerase; betanodavirus; nervous necrosis virus; ribavirin