title: Ligand exchange procedure for bimetallic magnetic iron-nickel nanocrystals toward biocompatible activities.
abstract: Bimetallic magnetic iron-nickel (FeNi) nanocrystals (NCs) were synthesized through a one-pot synthetic wet chemistry method, and the morphology of the resulting NCs can be adjusted by changing the molar ratio of chemical attendees during the experimental processes. The obtained FeNi NCs can be redispersed in water medium though the phase works by using the ligand exchange procedures of cysteine (Cys), 5-aminovaleric acid (5AA), and glutathione (GSH), respectively. The synthesized NCs exhibited excellent magnetic properties with Hc (magnetic fields, ≈10(-3) T) and μa (initial permeability of up to 10(5)). Furthermore, linear sweep voltammetry (LSV) polarization curves revealed a low overpotential of -0.47, -0.44, and 0.15 V and a current of 105.7, 97.8, and 209 mA for the Cys-, 5AA-, and GSH-FeNi NCs, respectively. This indicated a relatively high catalytic activity of these NCs in the hydrogen evolution reaction (HER). The different cell lines (AGS, HepG2, MG63, NCI-H460, and SK-MEL-2) exposed to FeNi NCs for 5 days exhibited >87% viability at concentrations of up to 50 μg mL(-1), which was indicative of excellent biocompatibility. The resulting FeNi NCs offer a facile synthetic route to fabricate monodispersed NCs. The biocompatibility of these NCs should also enable their application in electrocatalysis and biological applications.
authors.affiliation: †Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-735, Republic of Korea.
authors.forename: Xiang
authors.initials: X
authors.lastname: Mao
authors.affiliation: †Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-735, Republic of Korea.
authors.forename: Junyoung
authors.initials: J
authors.lastname: Kwon
authors.affiliation: ‡Department of Biomaterials Science, College of Natural Resources and Life Science, Pusan National University, 50 Cheonghak, Miryang 627-706, Republic of Korea.
authors.forename: Eun Kyoung
authors.initials: EK
authors.lastname: Koh
authors.affiliation: ‡Department of Biomaterials Science, College of Natural Resources and Life Science, Pusan National University, 50 Cheonghak, Miryang 627-706, Republic of Korea.
authors.forename: Dae Youn
authors.initials: DY
authors.lastname: Hwang
authors.affiliation: †Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 609-735, Republic of Korea.
authors.forename: Jaebeom
authors.initials: J
authors.lastname: Lee
mesh_terms: D002384:Catalysis; D007501:Iron / Q000737:chemistry*; D008024:Ligands; D008280:Magnetics / Q000295:instrumentation*; D053758:Nanoparticles / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*
chemical_list: D008024:Ligands; D009532:Nickel; D007501:Iron
keywords: bimetallic; biocompatibility; iron−-nickel (FeNi) nanocrystals (NCs); ligand exchange; magnetic