title: Surgical treatment in spine Paget's disease: a systematic review.
abstract: Paget's disease of bone (PDB) is a disease characterized by a disorder in the bone metabolism. The spine is the second region affected after the pelvis. Surgical treatment is reserved for cases refractory to medical treatment. We performed a systematic review of patients with Paget disease of bone affecting the spine, treated surgically in the last 30 years. The main objective of the review is to find out indications for surgery, outcomes of these patients and also the standard perioperative management.
authors.affiliation: Complexo Hospitalario Universitario de Santiago, Universidad de Santiago de Compostela, Santiago de Compostela, Spain. aljmora@gmail.com.
authors.forename: Alberto
authors.identifier: http://orcid.org/0000-0003-0143-1323
authors.initials: A
authors.lastname: Jorge-Mora
authors.affiliation: Complexo Hospitalario Universitario de Santiago, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.
authors.forename: Samer
authors.initials: S
authors.lastname: Amhaz-Escanlar
authors.affiliation: Hospital Nuestra Señora de La Esperanza, Universidade da Coruña, A Coruña, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Lois-Iglesias
authors.affiliation: Complexo Hospitalario Universitario de Santiago, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.
authors.forename: Susana
authors.initials: S
authors.lastname: Leborans-Eiris
authors.affiliation: Complexo Hospitalario Universitario de Santiago, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Pino-Minguez
mesh_terms: D001843:Bone Cements / Q000627:therapeutic use; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002574:Cervical Vertebrae / Q000601:surgery; D004164:Diphosphonates / Q000627:therapeutic use; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery; D010001:Osteitis Deformans / Q000601:surgery*; D019904:Polymethyl Methacrylate / Q000627:therapeutic use; D011183:Postoperative Complications / Q000209:etiology; D011300:Preoperative Care; D013122:Spinal Diseases / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D019904:Polymethyl Methacrylate
keywords: Paget’s disease; Spine; Surgery