title: A 37-year-old woman with refractory coeliac disease type II disease treated by stem cell transplantation.
abstract: This case study describes the disease course and treatment of a rare disorder, refractory coeliac disease. This disorder is associated with a marked increase in the risk of development of enteropathy-associated T-cell lymphoma. The patient in question developed coeliac symptoms despite strict adherence to a gluten-free diet, having been symptom-free for over 7 years. She presented with marked oedema of the legs and a distended abdomen. Investigations--laboratory, radiological and enteroscopy findings--were consistent with the development of refractory coeliac disease. This case illustrates the background and course of this disease, and the treatment options.
authors.affiliation: AMAU, GUH, Galway, Ireland.
authors.forename: Pardeep Kumar
authors.initials: PK
authors.lastname: Maheshwari
authors.affiliation: LUH, Limerick, Ireland.
authors.forename: Iain
authors.initials: I
authors.lastname: Feeley
authors.affiliation: LUH, Limerick, Ireland.
authors.forename: Hilary
authors.initials: H
authors.lastname: Oleary
authors.affiliation: AMAU, GUH, Galway, Ireland.
authors.forename: Carol
authors.initials: C
authors.lastname: Goulding
mesh_terms: D000328:Adult; D002446:Celiac Disease / Q000145:classification / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D055050:Diet, Gluten-Free; D058527:Enteropathy-Associated T-Cell Lymphoma / Q000209:etiology; D005260:Female; D006801:Humans; D033581:Stem Cell Transplantation