title: Toward Clinically Compatible Phase-Contrast Mammography.
abstract: Phase-contrast mammography using laboratory X-ray sources is a promising approach to overcome the relatively low sensitivity and specificity of clinical, absorption-based screening. Current research is mostly centered on identifying potential diagnostic benefits arising from phase-contrast and dark-field mammography and benchmarking the latter with conventional state-of-the-art imaging methods. So far, little effort has been made to adjust this novel imaging technique to clinical needs. In this article, we address the key points for a successful implementation to a clinical routine in the near future and present the very first dose-compatible and rapid scan-time phase-contrast mammograms of both a freshly dissected, cancer-bearing mastectomy specimen and a mammographic accreditation phantom.
authors.affiliation: Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Munich, Germany.
authors.forename: Kai
authors.initials: K
authors.lastname: Scherer
authors.affiliation: Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Munich, Germany.
authors.forename: Konstantin
authors.initials: K
authors.lastname: Willer
authors.affiliation: Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Munich, Germany.
authors.forename: Lukas
authors.initials: L
authors.lastname: Gromann
authors.affiliation: Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Munich, Germany.
authors.forename: Lorenz
authors.initials: L
authors.lastname: Birnbacher
authors.affiliation: Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Munich, Germany.
authors.forename: Eva
authors.initials: E
authors.lastname: Braig
authors.affiliation: Institute of Clinical Radiology, Ludwig-Maximilians-Universität München, Munich, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Grandl
authors.affiliation: Institute of Clinical Radiology, Ludwig-Maximilians-Universität München, Munich, Germany.
authors.forename: Anikó
authors.initials: A
authors.lastname: Sztrókay-Gaul
authors.affiliation: Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Munich, Germany.
authors.forename: Julia
authors.initials: J
authors.lastname: Herzen
authors.affiliation: Institute of Pathology, Ludwig-Maximilians-Universität München, Munich, Germany.
authors.forename: Doris
authors.initials: D
authors.lastname: Mayr
authors.affiliation: Institute of Clinical Radiology, Ludwig-Maximilians-Universität München, Munich, Germany.
authors.forename: Karin
authors.initials: K
authors.lastname: Hellerhoff
authors.affiliation: Lehrstuhl für Biomedizinische Physik, Physik-Department & Institut für Medizintechnik, Technische Universität München, Munich, Germany.
authors.forename: Franz
authors.initials: F
authors.lastname: Pfeiffer
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008327:Mammography / Q000379:methods*; D019047:Phantoms, Imaging; D011856:Radiographic Image Enhancement / Q000379:methods*