title: New norditerpenoid alkaloids from Aconitum vilmorinianum Komarov.
abstract: Aconitum vilmorinianum Komarov is a local medicinal plant used in many well-known clinical preparations to treat rheumatism and pains in Yunnan Province, China. Phytochemical examination of the roots of A. vilmorinianum led to the isolation of three novel imine-type norditerpenoid alkaloids named vilmorrianines E-G (1-3), and a new natural alkaloid N-desethyl-N-formyl-8-O-methyltalatisamine (4), together with 14 known alkaloids. Their structures were elucidated on the basis of spectroscopic evidence. Vilmorrianine E is the first known norditerpenoid alkaloid containing both an imine group and a three-membered ring formed by C8, C9, and C10.
authors.affiliation: Yunnan University of Traditional Chinese Medicine, 1076 Yuhua Rd., Chenggong Dist., Kunming, 650-500, People's Republic of China.
authors.forename: Cui-Ling
authors.initials: CL
authors.lastname: Chen
authors.forename: Wen-Hong
authors.initials: WH
authors.lastname: Tan
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhi-Ge
authors.initials: ZG
authors.lastname: Xue
authors.forename: Chun-Ping
authors.initials: CP
authors.lastname: Wan
authors.forename: Zhu-Ya
authors.initials: ZY
authors.lastname: Yang
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Zhou
authors.forename: Xiao-Xia
authors.initials: XX
authors.lastname: Ma
mesh_terms: D031841:Aconitum / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D004224:Diterpenes