title: A sole multi-analyte receptor responds with three distinct fluorescence signals: traffic signal like sensing of Al(3+), Zn(2+) and F(-).
abstract: A dialdehyde-based multi-analyte sensor renders distinctive emission spectra for Al(3+), Zn(2+) and F(-) ions. The ligand exhibited different types of interactions with these three different ions resulting in the enhancement of fluorescence intensity at three different wavelengths. All the sensing processes were studied in detail by absorption spectroscopy, emission spectroscopy and (1)H-NMR titration experiment. The ligand has the working ability in a wide pH range including the physiological pH. The ligand is non-toxic and amicable for sensing intracellular Al(3+) and Zn(2+) in live HeLa cells.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India. gdas@iitg.ernet.in.
authors.forename: Barun Kumar
authors.initials: BK
authors.lastname: Datta
authors.forename: Durairaj
authors.initials: D
authors.lastname: Thiyagarajan
authors.forename: Aiyagari
authors.initials: A
authors.lastname: Ramesh
authors.forename: Gopal
authors.initials: G
authors.lastname: Das
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000535:Aluminum / Q000032:analysis*; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000737:chemistry*; D005459:Fluorides / Q000032:analysis*; D006367:HeLa Cells; D006801:Humans; D007477:Ions / Q000032:analysis; D008958:Models, Molecular; D061848:Optical Imaging; D013050:Spectrometry, Fluorescence; D015032:Zinc / Q000032:analysis*
chemical_list: D000447:Aldehydes; D005456:Fluorescent Dyes; D007477:Ions; D000535:Aluminum; D015032:Zinc; D005459:Fluorides