title: Room transfers and the risk of delirium incidence amongst hospitalized elderly medical patients: a case-control study.
abstract: BACKGROUND
  Room transfers are suspected to promote the development of delirium in hospitalized elderly patients, but no studies have systematically examined the relationship between room transfers and delirium incidence. We used a case-control study to determine if the number of room transfers per patient days is associated with an increased incidence of delirium amongst hospitalized elderly medical patients, controlling for baseline risk factors.
  
  
  METHODS
  We included patients 70 years of age or older who were admitted to the internal medicine or geriatric medicine services at St. Michael's Hospital between October 2009 and September 2010 for more than 24 h. The cases consisted of patients who developed delirium during the first week of hospital stay. The controls consisted of patients who did not develop delirium during the first week of hospital stay. Patients with evidence of delirium at admission were excluded from the analysis. A multivariable logistic regression model was used to determine the relationship between room transfers and delirium development within the first week of hospital stay.
  
  
  RESULTS
  994 patients were included in the study, of which 126 developed delirium during the first week of hospital stay. Using a multivariable logistic regression model which controlled for age, gender, cognitive impairment, vision impairment, dehydration, and severe illness, room transfers per patient days were associated with delirium incidence (OR: 9.69, 95 % CI (6.20 to15.16), P < 0.0001).
  
  
  CONCLUSIONS
  An increased number of room transfers per patient days is associated with an increased incidence of delirium amongst hospitalized elderly medical patients. This is an exploratory analysis and needs confirmation with larger studies.
authors.affiliation: Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, 7th Floor East Building, Toronto, ON, M5B 1T8, Canada. amanda.goldberg@mail.utoronto.ca.
authors.forename: Amanda
authors.initials: A
authors.lastname: Goldberg
authors.affiliation: Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, 7th Floor East Building, Toronto, ON, M5B 1T8, Canada. sharon.straus@utoronto.ca.|Division of Geriatric Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada. sharon.straus@utoronto.ca.
authors.forename: Sharon E
authors.initials: SE
authors.lastname: Straus
authors.affiliation: Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, 7th Floor East Building, Toronto, ON, M5B 1T8, Canada. hamidj@smh.ca.|Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada. hamidj@smh.ca.
authors.forename: Jemila S
authors.initials: JS
authors.lastname: Hamid
authors.affiliation: Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, 7th Floor East Building, Toronto, ON, M5B 1T8, Canada. camilla.wong@utoronto.ca.|Division of Geriatric Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada. camilla.wong@utoronto.ca.|St. Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada. camilla.wong@utoronto.ca.
authors.forename: Camilla L
authors.initials: CL
authors.lastname: Wong
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003693:Delirium / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D005853:Geriatrics / Q000639:trends*; D006760:Hospitalization / Q000639:trends*; D006801:Humans; D015994:Incidence; D007388:Internal Medicine / Q000639:trends*; D007902:Length of Stay / Q000639:trends; D008297:Male; D010360:Patient Transfer / Q000639:trends*; D012307:Risk Factors