title: Epidemiology, Clinical Presentation, and Outcomes of Kawasaki Disease Among Hospitalized Children in an Inner City Hospital Before and After Publication of the American Academy of Pediatrics/American Heart Association Guidelines for Treatment of Kawasaki Disease: An 11-Year Period.
abstract: The effect of 2004 Kawasaki disease (KD) guidelines on diagnosis and outcome of KD is lacking. We studied the epidemiology of KD in our region and compared the incidence, presentation, and outcome of KD before and after publication of the guidelines. A retrospective chart review was conducted for patients admitted with a diagnosis of KD. Demographics, laboratory data, and clinical data were collected. Comparison was made between 2 groups: prepublication (2000-2004) and postpublication (2005-2009) of guidelines. A total of 312 children were included; 64% were African American, 23% White, and 2% Asian; 61% were boys; 79% were complete KD, and 66% were in winter/spring. There was a significant increase in KD cases over the 11 years. There was no significant difference in clinical findings and outcome between the 2 groups. KD admissions in our region significantly increased during the postpublication period. There was no difference in clinical presentation, laboratory findings, or outcome between the 2 groups.
authors.affiliation: Children's Hospital of Michigan, Detroit, MI, USA.
authors.forename: Swati
authors.initials: S
authors.lastname: Sehgal
authors.affiliation: Wayne State University School of Medicine, Detroit, MI, USA.
authors.forename: Xinguang
authors.initials: X
authors.lastname: Chen
authors.affiliation: Children's Hospital of Michigan, Detroit, MI, USA Wayne State University School of Medicine, Detroit, MI, USA jang@med.wayne.edu.
authors.forename: Jocelyn Y
authors.initials: JY
authors.lastname: Ang
mesh_terms: D000572:American Heart Association; D002648:Child; D002673:Child, Hospitalized / Q000706:statistics & numerical data*; D002675:Child, Preschool; D005260:Female; D006786:Hospitals, Urban; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008824:Michigan / Q000453:epidemiology; D009080:Mucocutaneous Lymph Node Syndrome / Q000453:epidemiology* / Q000628:therapy*; D010372:Pediatrics; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D012955:Societies, Medical; D016896:Treatment Outcome; D014481:United States
keywords: American Heart Association algorithm; Kawasaki disease; incidence