title: [SELENIUM EFFICIENCY IN PROPHYLAXIS AND COMPLEX TREATMENT OF DIFFUSE GOITER].
abstract: Efficiency of the combined prophylaxis and treatment of a diffuse goiter by preparations of sele- nium and iodine at 54 patients--men at the age of 41-50 years with the diagnosis of a diffuse goiter of 1st and 2nd degree was investigated. The diagnosis of a diffuse goiter was based on palpatory and ultrasonic research of the thyroid gland, which volume was compared with a body surface area. All surveyed have been divided into three groups. Patients of the first group accepted preparations of selenium and the iodine throughout three months, the second group--iodine preparations, in control group only dynamic supervision was spent. Thyroid gland volume at men who constantly used iodated salt and had no palpatory signs of a goiter was also measured for control. In the group which members accepted selenium and iodine preparations, at 11,8 % of patients was noted reduction of thyroid volume to normal and was revealed more expressed reduction of thyroid volume (for 2.15 sm3/M2 ± 0.07 sm3/M2), than at monotherapy by iodine preparations (for 0.92 sm3/M2 ± 0.17 sm3/M2). The conclusion was made that it is possible to recommend selenium preparations in a dose of 100 mkg a day together with preparations of iodine for prophylaxis and treatment of a diffuse goiter in conditions of the combined insufficiency in consumption of selenium and light deficiency of iodine.
authors.forename: O I
authors.initials: OI
authors.lastname: Osadtsiv
authors.forename: V I
authors.initials: VI
authors.lastname: Kravchenko
authors.forename: I M
authors.initials: IM
authors.lastname: Andrusyshyna
mesh_terms: D000328:Adult; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006042:Goiter / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011193:Potassium Iodide / Q000008:administration & dosage / Q000627:therapeutic use*; D018038:Sodium Selenite / Q000008:administration & dosage / Q000627:therapeutic use*; D013961:Thyroid Gland / Q000000981:diagnostic imaging / Q000187:drug effects; D016896:Treatment Outcome; D014455:Ukraine; D014463:Ultrasonography
chemical_list: D011193:Potassium Iodide; D018038:Sodium Selenite