title: Role of percutaneous mitral valve repair in the contemporary management of mitral regurgitation.
abstract: Percutaneous mitral valve (MV) repair has been performed in over 20,000 patients worldwide. As clinical experience in this technique grows indications for its use are being defined. Mitral regurgitation (MR) encompasses a complex heterogeneous group and its treatment is governed by determining a clear understanding of the underlying aetiology. Surgical MV repair remains the gold standard therapy for severe MR. However in select groups of high-risk surgical patients, a percutaneous approach to MV repair is establishing its role. This review gives an overview of the published data in percutaneous MV repair and its impact on the contemporary management of MR.
authors.affiliation: Department of Cardiology, Papworth Hospital NHS Foundation Trust, Cambridgeshire, UK.
authors.forename: Bushra S
authors.initials: BS
authors.lastname: Rana
authors.affiliation: Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK University of Birmingham, Birmingham, UK.
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Calvert
authors.affiliation: Cardiothoracic Department, Hammersmith Hospital, Imperial College London, London, UK.
authors.forename: Prakash P
authors.initials: PP
authors.lastname: Punjabi
authors.affiliation: Brighton University Hospital.
authors.forename: David
authors.initials: D
authors.lastname: Hildick-Smith
mesh_terms: D006328:Cardiac Catheterization / Q000009:adverse effects; D018618:Echocardiography, Doppler, Color; D019560:Echocardiography, Three-Dimensional; D017548:Echocardiography, Transesophageal; D004867:Equipment Design; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D058386:Mitral Valve Annuloplasty / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D020127:Recovery of Function; D016896:Treatment Outcome