title: Transition-metal-free visible-light photoredox catalysis at room-temperature for decarboxylative fluorination of aliphatic carboxylic acids by organic dyes.
abstract: We report herein an efficient, general and green method for decarboxylative fluorination of aliphatic carboxylic acids. By using a transition-metal-free, organocatalytic photoredox system, the reaction of various aliphatic carboxylic acids with the Selectfluor reagent afforded the corresponding alkyl fluorides in satisfactory yields under visible light irradiation at room temperature.
authors.affiliation: Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Load, Shanghai 200237, China. yejx@ecust.edu.cn.
authors.forename: Xinxin
authors.initials: X
authors.lastname: Wu
authors.forename: Chunna
authors.initials: C
authors.lastname: Meng
authors.forename: Xiaoqian
authors.initials: X
authors.lastname: Yuan
authors.forename: Xiaotong
authors.initials: X
authors.lastname: Jia
authors.forename: Xuhong
authors.initials: X
authors.lastname: Qian
authors.forename: Jinxing
authors.initials: J
authors.lastname: Ye
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D003653:Decarboxylation; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D008027:Light; D015394:Molecular Structure; D010084:Oxidation-Reduction; D055668:Photochemical Processes; D013696:Temperature
chemical_list: D002264:Carboxylic Acids; D006845:Hydrocarbons, Fluorinated