title: Evaluation of the use of low-level laser therapy in pain control in orthodontic patients: A randomized split-mouth clinical trial.
abstract: OBJECTIVE
  To evaluate the effect of using low-level laser therapy (LLLT) to control pain and discomfort during orthodontic treatment.
  
  
  METHODS
  A randomized, split-mouth clinical trial was conducted with 30 volunteers in need of orthodontic treatment, of both genders, aged between 18 and 40 years, who were randomly divided into two groups. One hemiarch was considered the exposed group (EG) and the other, the placebo group (PG). Both groups had elastic separators placed mesially and distally to the first molars of the two hemiarches at different times. The EG received an AIGaAs diode LLLT (810 nm, 100 mW, 2J/cm(2)) application for 15 seconds per point (interdental papilla at the mesial, distal, and near the root apex) immediately after separator placement on the maxillary right side. The PG also had elastics placed around the maxillary right molars, but received only simulated LLLT application. The elastics were left in place for 5 days, and after a waiting period of 1 week, they were inserted on the left side in both groups; however, the order of laser application was changed. While the separator remained in place, the patient marked his degree of perceived discomfort on a Visual Analog Scale (VAS) at 5 minutes (T0), 24 hours (T1), and 120 hours (T2), after LLLT application.
  
  
  RESULTS
  A statistically significant difference was observed (P < .005) in reducing discomfort in the exposed group compared with the placebo group. This reduction of discomfort in the EG was observed at all time intervals.
  
  
  CONCLUSIONS
  A sincle AIGaAs diode LLLT application may be indicated for the control or reduction of pain in the early stages of orthodontic treatment.
authors.affiliation: a  Master's Student, Graduate Program in Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil.
authors.forename: Rodrigo Duarte
authors.initials: RD
authors.lastname: Farias
authors.affiliation: b  Professor, Department of Orthodontics, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil.
authors.forename: Luciane Quadrado
authors.initials: LQ
authors.lastname: Closs
authors.affiliation: c  Professor, Department of Oral Medicine, School of Dentistry, Universidade Luterana do Brasil (ULBRA), Canoas, RS, Brazil.
authors.forename: Sergio Augusto Quevedo
authors.initials: SA
authors.lastname: Miguens
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D028022:Low-Level Light Therapy; D008297:Male; D009055:Mouth; D009971:Orthodontics, Corrective; D059408:Pain Management; D010147:Pain Measurement; D014087:Tooth Movement Techniques; D055815:Young Adult
keywords: Clinical trial; Low level laser therapy; Orthodontics; Pain