title: Gradual increase of chronic lymphocytic leukemia incidence in Korea, 1999-2010: comparison to plasma cell myeloma.
abstract: Chronic lymphocytic leukemia (CLL) and plasma cell myeloma (PCM) have markedly higher incidences in Western countries compared with Asian countries. To track the change of incidence in Korea, we investigated the 12-year incidence and compared findings with national cancer databases in Taiwan and the United States (US). The age-standardized incidence rates (ASRs) of CLL and PCM in Korea during 1999-2010 were 0.13/100,000 and 1.23/100,000. The annual percentage change (APC) in the incidence rates were 4.17% for CLL and 4.68% for PCM. These increasing trends were similar findings to Taiwan. In the US, the ASRs of CLL and PCM were 3.21/100 000 and 3.97/100,000. The APC of CLL and PCM incidence rate were 0.68% and 0.50%. The incidence rates of CLL in Korea gradually increased during the study period, while those of PCM showed a steeper ascent. In contrast, the incidence rates of CLL and PCM in the US appear to be stable.
authors.affiliation: a Department of Laboratory Medicine , Seoul National University College of Medicine , Seoul , Republic of Korea.
authors.forename: Seung Jun
authors.initials: SJ
authors.lastname: Lee
authors.affiliation: b Division of Hematology, Department of Internal Medicine , National Taiwan University Hospital , Taipei , Taiwan.
authors.forename: Hwei-Fang
authors.initials: HF
authors.lastname: Tien
authors.affiliation: c Cancer for Pediatric Oncology, National Cancer Center , Goyang , Republic of Korea.
authors.forename: Hyeon Jin
authors.initials: HJ
authors.lastname: Park
authors.affiliation: a Department of Laboratory Medicine , Seoul National University College of Medicine , Seoul , Republic of Korea.
authors.forename: Jung-Ah
authors.initials: JA
authors.lastname: Kim
authors.affiliation: a Department of Laboratory Medicine , Seoul National University College of Medicine , Seoul , Republic of Korea.|d Cancer Research Institute, Seoul National University College of Medicine , Seoul , Republic of Korea.
authors.forename: Dong Soon
authors.initials: DS
authors.lastname: Lee
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000453:epidemiology*; D008297:Male; D009101:Multiple Myeloma / Q000453:epidemiology*; D011159:Population Surveillance; D056910:Republic of Korea / Q000453:epidemiology
keywords: Chronic lymphocytic leukemia; incidence; plasma cell myeloma