title: The Effect of Channa striatus (Haruan) Extract on Pain and Wound Healing of Post-Lower Segment Caesarean Section Women.
abstract: Channa striatus has been consumed for decades as a remedy to promote wound healing by women during postpartum period. The objectives of this study were to compare postoperative pain, wound healing based on wound evaluation scale (WES), wound cosmetic appearance based on visual analogue scale (VAS) scores and patient satisfaction score (PSS), and safety profiles between C. striatus group and placebo group after six weeks of lower segment caesarean section (LSCS) delivery. A randomised, double-blind, placebo-controlled study was conducted. Subjects were randomised in a ratio of 1 : 1 into either the C. striatus group (500 mg daily) or placebo group (500 mg of maltodextrin daily). 76 subjects were successfully randomised, with 38 in the C. striatus group and 35 in the placebo group. There were no significant differences in postoperative pain (p = 0.814) and WES (p = 0.160) between the C. striatus and placebo groups. However, VAS and PSS in the C. striatus group were significantly better compared with the placebo group (p = 0.014 and p < 0.001, resp.). The safety profiles showed no significant differences between the groups. In conclusion, six-week supplementation of 500 mg of C. striatus extract showed marked differences in wound cosmetic appearance and patient's satisfaction and is safe for human consumption.
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Siti Zubaidah
authors.initials: SZ
authors.lastname: Ab Wahab
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Azidah
authors.initials: A
authors.lastname: Abdul Kadir
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Nik Hazlina
authors.initials: NH
authors.lastname: Nik Hussain
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Julia
authors.identifier: 0000-0003-4165-2673
authors.initials: J
authors.lastname: Omar
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Rohaizan
authors.initials: R
authors.lastname: Yunus
authors.affiliation: School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia.
authors.forename: Saringat
authors.initials: S
authors.lastname: Baie
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Norhayati
authors.identifier: 0000-0002-6372-1476
authors.initials: N
authors.lastname: Mohd Noor
authors.affiliation: School of Health Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Intan Idiana
authors.initials: II
authors.lastname: Hassan
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Wan Haslindawani
authors.initials: WH
authors.lastname: Wan Mahmood
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Asrenee
authors.initials: A
authors.lastname: Abd Razak
authors.affiliation: Obstetrics & Gynaecology Department, Hospital Raja Perempuan Zainab II, 15586 Kota Bharu, Kelantan, Malaysia.
authors.forename: Wan Zahanim
authors.initials: WZ
authors.lastname: Wan Yusoff