title: Intravitreal Bevacizumab After Intravitreal Triamcinolone for Exudative Age-Related Macular Degeneration.
abstract: OBJECTIVE
  This study aimed to assess the effect of intravitreal bevacizumab on visual acuity after a previously unsuccessful intravitreal triamcinolone acetonide injection for the treatment of exudative age-related macular degeneration.
  
  
  METHODS
  This is a clinically interventional case series study.
  
  
  METHODS
  This study included patients with exudative age-related macular degeneration who had previously received an intravitreal injection of approximately 25 mg of triamcinolone without an increase in visual acuity. Patients received 3.5 (2.3) injections [mean (SD)] of 1.5 mg of bevacizumab.
  
  
  RESULTS
  The study consisted of 36 patients (38 eyes) with a mean (SD) age of 77.9 (7.4) years. The mean (SD) visual acuity before the injection of bevacizumab was 0.84 (0.46) logMAR. After a mean (SD) follow-up of 10.1 (5.8) months (range, 2-21.9 months), the mean visual acuity was 0.94 (0.47) logMAR, without a statistically significant difference between the baseline value and the posttreatment value (P = 0.06; 95% confidence interval for the difference, -0.22 to 0.01 logMAR).
  
  
  CONCLUSIONS
  Intravitreal bevacizumab injections may not markedly improve vision in exudative age-related macular degeneration if previous intravitreal triamcinolone failed to increase visual acuity.
authors.affiliation: From the *Department of Ophthalmology, Faculty of Clinical Medicine Mannheim of the Ruprecht-Karls-University Heidelberg, Germany; and †Department of Ophthalmology, II University of Naples, Naples, Italy.
authors.forename: Jost B
authors.initials: JB
authors.lastname: Jonas
authors.forename: Teodosio
authors.initials: T
authors.lastname: Libondi
authors.forename: Lidia
authors.initials: L
authors.lastname: Golubkina