title: Assessment of the Facial Soft Tissue Thickness of the Patients Affected by Unilateral Cleft Lip and Palate Using Cone Beam Computed Tomography.
abstract: OBJECTIVE
  The aim of the study was to evaluate the soft tissue thickness of the patients affected by unilateral cleft lip and palate (UCLP) and to compare the findings with a matched control group without cleft using cone beam computed tomography (CBCT).
  
  
  METHODS
  The study sample consisted of 66 patients (31 women and 35 men) divided into 2 groups as UCLP group (34 patients; 23 men and 11 women; 9 right sided and 25 left sided; mean age: 14.11 ± 3.48 years) and control group (32 patients; 12 men and 20 women; mean age: 15.10 ± 3.13 years) without any cleft. Angular angle between Nasion-A line and Nasion-B line (ANB), angle between Sella-Nasion line and Gonion-Menton line (SN-MP) and linear (glabella, nasion, rhinion, subnasale, labrale superius, stomion, labrale inferius, labiomentale, pogonion, and gnathion) measurements were done using CBCT. Student t test was performed to compare the variables between the groups.
  
  
  RESULTS
  Soft tissue thickness values for men were higher in both groups, except for rhinion and glabella. Subnasale for women (P = 0.000), men (P = 0.006), and total samples (P = 0.000) and the variable of the labrale superius for men (P = 0.047) and total samples (P = 0.040) were found to be statistically significantly thinner in the UCLP group. SN-MP had significant affect on subnasale thickness (R = 15.8; Beta = -0.397; P = 0.001).
  
  
  CONCLUSIONS
  Thickness of the subnasale and the labrale superius were found to be statistically significantly thinner in the UCLP group compared with the controls.
authors.affiliation: *Department of Orthodontics, Faculty of Dentistry, Akdeniz University, Antalya †Department of Orthodontics, Faculty of Dentistry, Ordu University, Ordu ‡Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.
authors.forename: Mevlüt
authors.initials: M
authors.lastname: Celikoglu
authors.forename: S Kutalmiş
authors.initials: SK
authors.lastname: Buyuk
authors.forename: A Ercan
authors.initials: AE
authors.lastname: Sekerci
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002508:Cephalometry / Q000379:methods*; D002648:Child; D002680:Chin / Q000000981:diagnostic imaging; D002971:Cleft Lip / Q000000981:diagnostic imaging*; D002972:Cleft Palate / Q000000981:diagnostic imaging*; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D005145:Face / Q000000981:diagnostic imaging*; D005260:Female; D005546:Forehead / Q000000981:diagnostic imaging; D006801:Humans; D008046:Lip / Q000000981:diagnostic imaging; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging; D008437:Maxilla / Q000000981:diagnostic imaging; D009295:Nasal Bone / Q000000981:diagnostic imaging; D009666:Nose / Q000000981:diagnostic imaging; D012658:Sella Turcica / Q000000981:diagnostic imaging; D012737:Sex Factors; D055815:Young Adult