title: [Hypotonic Versus Isotonic Electrolyte Solution for Perioperative Fluid Therapy in Infants].
abstract: BACKGROUND
  This study was designed to evaluate the effects of perioperative administration of an isotonic electrolyte solution with 1% glucose (IT) on blood sodium (Na+) and blood glucose (BG) concentrations in pediatric patients < 1-year-old undergoing plastic surgery in comparison with a conventional hypotonic electrolyte solution with 2.6% glucose (HT).
  
  
  METHODS
  Fifty Patients were randomly allocated to HT group and IT group. Na+ and BG were measured at induction of anesthesia (Tind), the end of surgery (Tend), and 4 hours after surgery (T4h).
  
  
  RESULTS
  Patient characteristics were similar for the 2 groups. In the HT group, Na+ at Tend insignificantly dropped compared with that at Tind, whereas in the IT group Na+ was significantly elevated. Na+ at T4h significantly increased compared with that at Tend in each group. No cases developed new dysnatremia or dysglycemia in IT group. The incidence of hyponatremia at Tend was significantly lower in the IT group. A positive correlation between intraoperative Na+ concentration changes and the infusion duration was observed in the IT group.
  
  
  CONCLUSIONS
  Isotonic solution with 1% glucose is suggested to be safe in infants during and after surgery.
authors.forename: Kiyoko
authors.initials: K
authors.lastname: Bito
authors.forename: Satoshi
authors.initials: S
authors.lastname: Higuchi
authors.forename: Azusa
authors.initials: A
authors.lastname: Omura
authors.forename: Yuri
authors.initials: Y
authors.lastname: Kaneda
authors.forename: Reiko
authors.initials: R
authors.lastname: Otaki
authors.forename: Satomi
authors.initials: S
authors.lastname: Azuma
authors.forename: Mikiko
authors.initials: M
authors.lastname: Kojima
authors.forename: Naoki
authors.initials: N
authors.lastname: Otsuka
authors.forename: Kenji
authors.initials: K
authors.lastname: Shida
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Yasumoto
mesh_terms: D004573:Electrolytes; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007038:Hypotonic Solutions; D007223:Infant; D007552:Isotonic Solutions; D008297:Male; D019990:Perioperative Care / Q000379:methods*; D011446:Prospective Studies
chemical_list: D004573:Electrolytes; D007038:Hypotonic Solutions; D007552:Isotonic Solutions