title: Primary localized cutaneous nodular amyloidosis of the thighs.
abstract: Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare form of cutaneous amyloidosis. We report the case of a 65-year-old woman with multiple asymptomatic discrete nodules and atrophic plaques on the thighs of 4 years' duration that had increased in number and size. Results of extensive clinical, histologic, and laboratory evaluation showed no evidence of systemic amyloidosis or myeloma. A diagnosis of PLCNA was made. The patient refused treatment due to the asymptomatic nature of the lesions, and follow-up examination 2.5 years later showed minimal progression of the disease.
authors.affiliation: Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, 400038 China. zhaizf1004@163.com.
authors.forename: Zhifang
authors.initials: Z
authors.lastname: Zhai
authors.forename: Fei
authors.initials: F
authors.lastname: Hao
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Song
authors.forename: Xichuan
authors.initials: X
authors.lastname: Yang
mesh_terms: D000368:Aged; D028226:Amyloidosis, Familial / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D012873:Skin Diseases, Genetic / Q000175:diagnosis* / Q000473:pathology; D013848:Thigh