title: Effects of fetal cardiac anomalies on ductus venosus and aortic isthmus doppler profiles.
abstract: OBJECTIVE
  To demonstrate the blood flow profiles of fetuses with cardiac anomalies at the level of Ductus venosus (DV) and Aortic isthmus (AI) to evaluate the effects of fetal cardiac anomalies on these profiles, and how these profile changes contribute to cardiac anomaly screening studies as a marker.
  
  
  METHODS
  DV and AI doppler studies were applied to 64 singleton pregnant women with fetal cardiac anomalies and 74 pregnant women with healthy fetuses. DV-PVIV (peak velocity index for veins) for DV and IFI (isthmic flow index) for AI were used.
  
  
  RESULTS
  DV doppler studies in fetuses with cardiac anomalies and healthy fetuses did not show statistically significant difference. But the results of the AI doppler studies had statistically significant difference in the fetal cardiac anomaly group with the exception of cases with dilatation and regurgitation. When right-sided heart anomaly and the remaining cases were compared with the control groups, AI doppler results also showed lower IFI values.
  
  
  CONCLUSIONS
  DV doppler studies in the second or third trimester may not be suitable as a screening test for congenital heart disease, but AI doppler studies might be considered as a supporting parameter. But further studies are needed for routine clinical use.
authors.affiliation: Suleymaniye Research and Education Hospital, Istanbul, Turkey. gulsah.keskin.84@hotmail.com.
authors.forename: Gülşah
authors.initials: G
authors.lastname: İlhan
authors.affiliation: İstanbul University İstanbul Medical Faculty, Istanbul, Turkey. Cem.iyi@yahoo.com.
authors.forename: Ahmet Cem
authors.initials: AC
authors.lastname: İyibozkurt
authors.affiliation: İstanbul University İstanbul Medical Faculty, Istanbul, Turkey. i.kalelioglu.@gmail.com.
authors.forename: Halil İbrahim
authors.initials: Hİ
authors.lastname: Kalelioğlu
authors.affiliation: İstanbul University İstanbul Medical Faculty, Istanbul, Turkey. lemi.ibrahimoglu.@gmail.com.
authors.forename: Lemi
authors.initials: L
authors.lastname: İbrahimoğlu
authors.affiliation: Suleymaniye Research and Education Hospital, Istanbul, Turkey. galenusgz@hotmail.com.
authors.forename: Ali Galip
authors.initials: AG
authors.lastname: Zebitay
authors.affiliation: Zeynep Kamil Research and Education Hospital, Istanbul, Turkey. meryemkurek@yahoo.com.
authors.forename: Meryem Kürek
authors.initials: MK
authors.lastname: Eken
authors.affiliation: Balıkesir State Hospital, Balıkesir, Turkey. afgokmen@gmail.com.
authors.forename: Ayşe Filiz Gökmen
authors.initials: AF
authors.lastname: Karasu
mesh_terms: D000328:Adult; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging*; D001783:Blood Flow Velocity / Q000502:physiology*; D015150:Echocardiography, Doppler; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging; D005318:Fetal Heart / Q000000981:diagnostic imaging* / Q000196:embryology; D005865:Gestational Age; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D018608:Ultrasonography, Doppler / Q000379:methods*; D016216:Ultrasonography, Prenatal / Q000379:methods; D014680:Veins / Q000000981:diagnostic imaging*
keywords: Aortic isthmus; Doppler; Ductus venosus; Fetal cardiac anomaly