title: [Prognostic factors related to mortality in newborns with necrotising enterocolitis].
abstract: BACKGROUND
  Necrotizing enterocolitis is the most frequent and severe acquired gastrointestinal disease in newborns and still has high mortality. There are few published papers about prognostic factors of death in our country.
  
  
  OBJECTIVE
  To know the factors associated with death in patients with necrotizing enterocolitis.
  
  
  METHODS
  Retrospective, descriptive, comparative study with a case-control design was conducted on patients with necrotizing enterocolitis during a 5-year period.
  
  
  RESULTS
  Deceased patients had significantly lower platelet counts compared to survivors (P=0.022) and the prognostic factors associated with mortality were anaemia (P=0.006, OR = 15.62), stage III of necrotizing enterocolitis (P<0.001, OR = 47.5), to require surgical treatment (P<0.001, OR = 47.5), to have intestinal necrosis (P=0.001, OR = 48.5) or perforation (P=0.016, OR =24.25), to have medical complications, specifically intravascular disseminated coagulation (P<.001, RR = 98), and multi-organ failure (P<0.001, RR = 2). It was also found that patients with gastrointestinal symptoms and diagnosis of necrotising enterocolitis when they were hospitalized were more likely to have surgical treatment.
  
  
  CONCLUSIONS
  We must be aware of the factors associated with mortality, as well as those associated with surgical treatment to reduce overall mortality for this condition.
authors.affiliation: Departamento de Cirugía General, Hospital Infantil de México Federico Gómez, Secretaría de Salud, México D.F., México. Electronic address: brachoblanchet@gmail.com.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Bracho-Blanchet
authors.affiliation: Departamento de Pediatría, Hospital Infantil de México Federico Gómez, Secretaría de Salud, México D.F., México.
authors.forename: María Esther
authors.initials: ME
authors.lastname: Torrecilla-Navarrete
authors.affiliation: Departamento de Cirugía General, Hospital Infantil de México Federico Gómez, Secretaría de Salud, México D.F., México.
authors.forename: Cristian
authors.initials: C
authors.lastname: Zalles-Vidal
authors.affiliation: Departamento de Neonatología, Hospital Infantil de México Federico Gómez, Secretaría de Salud, México D.F., México.
authors.forename: Daniel
authors.initials: D
authors.lastname: Ibarra-Ríos
authors.affiliation: Departamento de Cirugía General, Hospital Infantil de México Federico Gómez, Secretaría de Salud, México D.F., México.
authors.forename: Emilio
authors.initials: E
authors.lastname: Fernández-Portilla
authors.affiliation: Departamento de Cirugía General, Hospital Infantil de México Federico Gómez, Secretaría de Salud, México D.F., México.
authors.forename: Roberto
authors.initials: R
authors.lastname: Dávila-Pérez
mesh_terms: D016022:Case-Control Studies; D020345:Enterocolitis, Necrotizing / Q000401:mortality*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies
keywords: Enterocolitis necrosante; Mortalidad; Mortality; Necrotising enterocolitis; Newborn; Prognosis; Pronóstico; Recién nacido