title: Stability assessment in ligand-binding assays: a critical parameter for data integrity.
authors.affiliation: Department of Pharmacokinetic & Drug Metabolism, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA.
authors.forename: Theingi M
authors.initials: TM
authors.lastname: Thway
authors.affiliation: Department of Immunochemistry & Biomarker Development, Bristol-Myers Squibb, Route 206 & Province Line Road, Princeton, NJ 08543, USA.
authors.forename: Binodh
authors.initials: B
authors.lastname: DeSilva
mesh_terms: D015415:Biomarkers / Q000032:analysis / Q000378:metabolism; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D004355:Drug Stability; D006801:Humans; D018796:Immunoconjugates / Q000032:analysis / Q000378:metabolism / Q000493:pharmacokinetics; D008024:Ligands; D055550:Protein Stability; D011506:Proteins / Q000032:analysis / Q000378:metabolism / Q000493:pharmacokinetics
chemical_list: D015415:Biomarkers; D018796:Immunoconjugates; D008024:Ligands; D011506:Proteins
keywords: analyte stability; biotransformation; test article stability