title: Choroidal metastasis from primary bone leiomyosarcoma.
abstract: Choroidal metastases, the most common form of intraocular malignancies, are principally caused by primary tumors from breast, lung, and gastrointestinal tract. These lesions are mostly symptomatic and rarely detected incidentally in the extension study of a previously diagnosed tumor. Leiomyosarcoma is a neoplasm of mesenchymal cells with smooth muscle differentiation and represents the most prevalent soft-tissue sarcoma. Leiomyosarcoma is a notably rare tumor in ophthalmic region. We report a case of primary bone leiomyosarcoma metastatic to the choroid that was treated with chemotherapy and surgery. Although three cases of choroidal metastasis from leiomyosarcomas have been already reported, to our knowledge this is the first case of choroidal metastasis from primary bone leiomyosarcoma.
authors.affiliation: Department of Ophthalmology, University Hospital of Salamanca, Salamanca, Spain, cristina_nietogomez@hotmail.com.
authors.forename: Nieto Gómez
authors.initials: NG
authors.lastname: Cristina
authors.forename: Escudero Domínguez
authors.initials: ED
authors.lastname: Francisco
authors.forename: Rivero Gutiérrez
authors.initials: RG
authors.lastname: Vanesa
authors.forename: Cruz González
authors.initials: CG
authors.lastname: Fernando
authors.forename: Cacharro Moras
authors.initials: CM
authors.lastname: Luis
authors.forename: Hernández Galilea
authors.initials: HG
authors.lastname: Emiliano
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology*; D002830:Choroid Neoplasms / Q000556:secondary*; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000556:secondary*