title: Intraoperative neurophysiology in deep brain surgery for psychogenic dystonia.
abstract: Psychogenic dystonia is a challenging entity to diagnose and treat because little is known about its pathophysiology. We describe two cases of psychogenic dystonia who underwent deep brain stimulation when thought to have organic dystonia. The intraoperative microelectrode recordings in globus pallidus internus were retrospectively compared with those of five patients with known DYT1 dystonia using spontaneous discharge parameters of rate and bursting, as well as movement-related discharges. Our data suggest that simple intraoperative neurophysiology measures in single subjects do not differentiate psychogenic dystonia from DYT1 dystonia.
authors.affiliation: Human Motor Control, NIH-NINDS Bethesda, Maryland, 20814.
authors.forename: Vesper Fe Marie L
authors.initials: VF
authors.lastname: Ramos
authors.affiliation: Human Motor Control, NIH-NINDS Bethesda, Maryland, 20814.
authors.forename: Ajay S
authors.initials: AS
authors.lastname: Pillai
authors.affiliation: Parkinson Clinic, NIH-NINDS Bethesda, Maryland, 20814.
authors.forename: Codrin
authors.initials: C
authors.lastname: Lungu
authors.affiliation: Surgical Movement Disorders Center, UCSF San Francisco, California, 94115.
authors.forename: Jill
authors.initials: J
authors.lastname: Ostrem
authors.affiliation: Neurological Surgery, UCSF San Francisco, California, 94143.
authors.forename: Philip
authors.initials: P
authors.lastname: Starr
authors.affiliation: Human Motor Control, NIH-NINDS Bethesda, Maryland, 20814.
authors.forename: Mark
authors.initials: M
authors.lastname: Hallett