title: Extramedullary hematopoiesis in renal allograft.
abstract: Extramedullary hematopoiesis (EMH), defined as the presence of hematopoietic elements outside of the medullary cavity of bone, has been reported in patients with various hematopoietic neoplasms including myelofibrosis. EMH commonly occurs in the liver and spleen (resulting in hepatosplenomegaly) and uncommonly involves the kidney. EMH involving the allograft kidney has not been reported in English literature. Herein, we report the first case of EMH in allograft kidney in a patient with myelofibrosis. The clinical and pathological findings are described. Through comparison of the medullary neoplastic infiltrate with the renal allograft infiltrate, we postulate the neoplastic nature of the infiltrate in the allograft kidney.
authors.affiliation: Department of Pathology , Saint Louis University School of Medicine , St. Louis, MO , USA.
authors.forename: Guilan
authors.initials: G
authors.lastname: Chen
authors.affiliation: Department of Nephrology , Saint Louis University School of Medicine , St. Louis, MO , USA.
authors.forename: Reza
authors.initials: R
authors.lastname: Ali
authors.affiliation: Department of Pathology , Saint Louis University School of Medicine , St. Louis, MO , USA.
authors.forename: Mark M
authors.initials: MM
authors.lastname: Shuldberg
authors.affiliation: Department of Nephrology , Saint Louis University School of Medicine , St. Louis, MO , USA.
authors.forename: Bahar
authors.initials: B
authors.lastname: Bastani
authors.affiliation: Department of Pathology , Saint Louis University School of Medicine , St. Louis, MO , USA.
authors.forename: David S
authors.initials: DS
authors.lastname: Brink
keywords: allograft; biopsy; extramedullary hematopoiesis; myelofibrosis; transplant