title: Neuropsychological tests for predicting cognitive decline in older adults.
abstract: OBJECTIVE
  To determine neuropsychological tests likely to predict cognitive decline.
  
  
  METHODS
  A sample of nonconverters (n = 106) was compared with those who declined in cognitive status (n = 24). Significant univariate logistic regression prediction models were used to create multivariate logistic regression models to predict decline based on initial neuropsychological testing.
  
  
  RESULTS
  Rey-Osterrieth Complex Figure Test (RCFT) Retention predicted conversion to mild cognitive impairment (MCI) while baseline Buschke Delay predicted conversion to Alzheimer's disease (AD). Due to group sample size differences, additional analyses were conducted using a subsample of demographically matched nonconverters. Analyses indicated RCFT Retention predicted conversion to MCI and AD, and Buschke Delay predicted conversion to AD.
  
  
  CONCLUSIONS
  Results suggest RCFT Retention and Buschke Delay may be useful in predicting cognitive decline.
authors.affiliation: Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, CA 90095-6980, USA.|Veteran Affairs Long Beach Healthcare System, Long Beach, CA 90822, USA.
authors.forename: Kimberly M
authors.initials: KM
authors.lastname: Baerresen
authors.affiliation: Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, CA 90095-6980, USA.
authors.forename: Karen J
authors.initials: KJ
authors.lastname: Miller
authors.affiliation: Department of Psychology, Loma Linda University, Loma Linda, CA 92350, USA.
authors.forename: Eric R
authors.initials: ER
authors.lastname: Hanson
authors.affiliation: Fuller Theological Seminary, Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, CA 90095-6980, USA.
authors.forename: Justin S
authors.initials: JS
authors.lastname: Miller
authors.affiliation: Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, CA 90095-6980, USA.
authors.forename: Richelin V
authors.initials: RV
authors.lastname: Dye
authors.affiliation: Department of Psychology, Loma Linda University, Loma Linda, CA 92350, USA.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Hartman
authors.affiliation: Department of Psychology, Loma Linda University, Loma Linda, CA 92350, USA.
authors.forename: David
authors.initials: D
authors.lastname: Vermeersch
authors.affiliation: Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles, CA 90095-6980, USA.
authors.forename: Gary W
authors.initials: GW
authors.lastname: Small
mesh_terms: D000375:Aging / Q000523:psychology; D000544:Alzheimer Disease / Q000175:diagnosis*; D060825:Cognitive Dysfunction / Q000175:diagnosis*; D018450:Disease Progression; D006801:Humans; D016015:Logistic Models; D008137:Longitudinal Studies; D008875:Middle Aged; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011379:Prognosis
keywords: Alzheimer's disease; cognitive decline; conversion; memory disorder; mild cognitive impairment