title: A Case of Disseminated Cryptococcal Infection and Concurrent Lung Tuberculosis in a Patient under Steroid Therapy for Interstitial Pneumonia.
abstract: Both disseminated cryptococcal infection and tuberculosis occur in hosts with impaired cell-mediated immunity, but there have been few reports about the concurrent infections in patients without human immunodeficiency virus infection. A 64-year-old man, who had been taking corticosteroids for interstitial pneumonia, was diagnosed with disseminated cryptococcal infection. While the patient was receiving anticryptococcal therapy, pulmonary tuberculosis also emerged. The patient developed acute exacerbation of interstitial pneumonia and passed away. Based on the patient's clinical course, serial computed tomography images, and autopsy results, we believe that the preceding several months of corticosteroid treatment might have contributed to these coinfections in the lungs already vulnerable due to underlying fibrosis.
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Japan.
authors.forename: Aoi
authors.initials: A
authors.lastname: Kuroda
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Japan.
authors.forename: Sadatomo
authors.identifier: 0000-0003-4861-4143
authors.initials: S
authors.lastname: Tasaka
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Japan.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Yagi
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Mochimaru
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Japan.
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Tani
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Japan.
authors.forename: Ho
authors.initials: H
authors.lastname: Namkoong
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Kawasaki Municipal Hospital, Japan.
authors.forename: Kyuto
authors.initials: K
authors.lastname: Tanaka
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Suzuki
authors.affiliation: Department of Pathology, Keio University School of Medicine, Japan.
authors.forename: Mami
authors.initials: M
authors.lastname: Hatano
authors.affiliation: Center for Infectious Diseases and Infection Control, Keio University School of Medicine, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Hasegawa
authors.affiliation: Department of Pathology, Keio University School of Medicine, Japan.
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Okada
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Keio University School of Medicine, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Betsuyaku