title: Translating Membrane Tension into Cytoskeletal Action by FBP17.
abstract: A recent article by Tsujita et al. (2015) in Nature Cell Biology provides insight into how cells sense and translate plasma membrane tension toward polarized actin polymerization and migration. They identify FBP17 as a multifunctional adaptor that senses membrane curvature and delivers feedback to actin dynamics and directed cell migration.
authors.affiliation: Department of Cell Biology, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands. Electronic address: mirjam.zegers@radboudumc.nl.
authors.forename: Mirjam M
authors.initials: MM
authors.lastname: Zegers
authors.affiliation: Department of Cell Biology, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; David H. Koch Center for Applied Research of Genitourinary Cancers, Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA; Cancer Genomics Centre Netherlands (CGC.nl), 3584 CG Utrecht, the Netherlands. Electronic address: peter.friedl@radboudumc.nl.
authors.forename: Peter
authors.initials: P
authors.lastname: Friedl
mesh_terms: D000199:Actins / Q000378:metabolism*; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology*; D016764:Cell Polarity / Q000502:physiology*; D006801:Humans
chemical_list: D000199:Actins; D002352:Carrier Proteins