title: [Analysis of the Detection for the LPD Patients with EB Infection].
abstract: OBJECTIVE
  To analyze the detection results for the patients with lymphoproliferative disease(LPD) accompanied with the infection of EB.
  
  
  METHODS
  The EBV specific antibody, serum cytokine, EBV DNA copy number in peripheral blood mononuclear cells (PBMNC) of 70 LPD patients and 70 healthy volunteers were analyzed and compared.
  
  
  RESULTS
  The positive rates of VCA-IgG and VCA-IgM were not significantly different in two groups (P>0.05); The positive rate of EA-IgG in the PLD patient group was higher than that in the control group (P<0.05); the levels of IL-18 and IFN-γ were not significantly different between the 2 group (P>0.05); the EBV DNA copy number in PBMNC of the PLD patient group was higher than that in the control group (P<0.05).
  
  
  CONCLUSIONS
  The patients with LPD show the active infection of EBV, that is the main reason for the abnormal function of lymphatic system in the patients with LPD. The active infection of EBV maybe involve in PLD pathogenesis.
authors.affiliation: Department of Clinical Laboratorial Examination, The Traditional Chinese Medicine Hospital of Funing County, Funing 066300, Hebei Province, China. E-mail: wsujin@126.com.
authors.forename: Jin
authors.initials: J
authors.lastname: Su
authors.affiliation: Department of Clinical Laboratorial Examination, The First Hospital of Qinhuangdao City, Qinhuangdao 066000, Hebi Province, China.
authors.forename: Shu-Yi
authors.initials: SY
authors.lastname: Wang
authors.affiliation: Department of Clinical Laboratorial Examination, The Third Hospital of Qinhuangdao City, Qinhuangdao 066000, Hebi Province, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
mesh_terms: D016207:Cytokines; D018076:DNA, Complementary; D004279:DNA, Viral; D020031:Epstein-Barr Virus Infections; D004854:Herpesvirus 4, Human; D006801:Humans; D007963:Leukocytes, Mononuclear; D008232:Lymphoproliferative Disorders
chemical_list: D016207:Cytokines; D018076:DNA, Complementary; D004279:DNA, Viral