title: PROGRESSION OF AGE-RELATED MACULAR DEGENERATION OVERLYING A LARGE CHOROIDAL VESSEL.
abstract: OBJECTIVE
  To describe a patient who showed progression of age-related macular degeneration along the course of an underlying large choroidal vessel.
  
  
  METHODS
  Retrospective case report.
  
  
  RESULTS
  An 84-year-old woman was diagnosed with age-related macular degeneration and followed for more than 6 years. Retinal pigment epithelial changes were more advanced in her right eye which had a thinner choroid than the fellow left eye. Multimodal imaging with swept-source optical coherence tomography showed that the progression of outer retinal and retinal pigment epithelial changes appeared to follow the course of a large choroidal vessel.
  
  
  CONCLUSIONS
  The authors hypothesize that large choroidal vessels can compress the overlying choriocapillaris, possibly leading to outer retinal ischemia, which subsequently could focally accelerate the course of age-related macular degeneration.
authors.affiliation: *Vitreous Retina Macula Consultants of New York, New York, NY; †The LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Hospital, New York, NY; and ‡Department of Ophthalmology, New York University School of Medicine, New York, NY.
authors.forename: Maiko
authors.initials: M
authors.lastname: Inoue
authors.forename: Kunal K
authors.initials: KK
authors.lastname: Dansingani
authors.forename: K Bailey
authors.initials: KB
authors.lastname: Freund
mesh_terms: D000369:Aged, 80 and over; D002829:Choroid / Q000473:pathology*; D005260:Female; D006801:Humans; D055213:Retinal Pigment Epithelium / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology*; D012189:Retrospective Studies; D057135:Wet Macular Degeneration / Q000473:pathology*