title: Anomalous Vascular Patterns of the Optic Disc in Amblyopia.
abstract: OBJECTIVE
  To evaluate the presence of anomalies of the optic disc vascular patterns in subjects with amblyopia.
  
  
  METHODS
  Case controlled study. The outcome measure is temporal deviation of central retinal vessels and / or vascular pattern asymmetry.
  
  
  METHODS
  A total of 342 hyperopic amblyopic patients were evaluated. An additional 88 subjects with equal visual acuity with strabismus, and 108 subjects with equal visual acuity and anisometropia were evaluated.
  
  
  RESULTS
  In this study, more than 50% of amblyopic patients had optic disc deformities. Sixty-five percent of subjects with amblyopia, orthophoria, and anisometropia exceeding 1.5 D had these anomalies compared with less than 7% of the groups without amblyopia or strabismus.
  
  
  CONCLUSIONS
  These disc anomalies may be associated with disorganization of optic nerve axons. This finding indicates the possibility of a peripheral cause for impaired vision and could provide an explanation for the variability in visual defects associated with amblyopia. Optic nerve imaging should be incorporated into clinical protocols for amblyopia research.
authors.affiliation: From the Cayuga Medical Center, Ithaca, New York.
authors.forename: Philip
authors.initials: P
authors.lastname: Lempert