title: Increased Mitochondrial Activity in Anthrax-Induced Cell Death.
abstract: Pathogenesis of anthrax lethal toxin (LT) is attributed to its ability to cause death of infected cells. New work has demonstrated that increase of mitochondrial F1F0 ATPase activity and subsequent depletion of cellular ATP level are critical early events during LT-induced cell death.
authors.affiliation: Molecular Targets Group, James Graham Brown Cancer Center, Department of Pharmacology and Toxicology, University of Louisville, KY 40202.
authors.forename: Chi
authors.initials: C
authors.lastname: Li
keywords: F1F0 ATPase; anthrax; mitochondria; pyroptosis