title: Feeding Arteries of Primary Tongue Cancers on Intra-arterial Infusion Chemotherapy.
abstract: OBJECTIVE
  To evaluate the frequency and the predictive factor of each feeding artery on intra-arterial infusion chemotherapy (IAIC) in primary tongue cancer.
  
  
  METHODS
  We retrospectively evaluated 20 patients who received IAIC for primary tongue cancer. The main and accompanying feeding arteries were identified on super-selective angiography of the branches of the external carotid artery. Tumor diameter, and extension to the contralateral side, tongue extrinsic muscles (TEMs), and lateral mesopharyngeal wall were determined based on magnetic resonance imaging or computed tomography findings.
  
  
  RESULTS
  The main feeding artery was the ipsilateral lingual artery (LA) in 15 of the 20 examined tumors and the contralateral LA in the other 5. Ten cancers had only one feeding artery, and multiple feeding arteries were detected in the remaining 10. Tumors >4 cm (n = 9), those with extension to the contralateral side (n = 13), and those with extension to TEMs (n = 15) were supplied by significantly larger numbers of feeding arteries compared to tumors without these features (P = 0.01, 0.049, and 0.02, respectively). The frequency of feeding from the contralateral LA was 64 % (9/14) and 17 % (1/6) in tumors with and without extension to the contralateral side, respectively. Feeding from a facial artery (FA) was not detected in tumors ≤4 cm, while 5 of the 9 (56 %) tumors >4 cm were supplied by a FA (P = 0.01).
  
  
  CONCLUSIONS
  A careful search for feeding arteries is required, especially in large tumors with extension to the contralateral side or to TEMs.
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. kamitani@radiol.med.kyushu-u.ac.jp.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kamitani
authors.affiliation: Department of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. kawanami_01@mac.com.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kawanami
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. asayama@radiol.med.kyushu-u.ac.jp.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Asayama
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. yymatsuo@radiol.med.kyushu-u.ac.jp.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Matsuo
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. ymasato@radiol.med.kyushu-u.ac.jp.
authors.forename: Masato
authors.initials: M
authors.lastname: Yonezawa
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. yyama@radiol.med.kyushu-u.ac.jp.
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Yamasaki
authors.affiliation: Department of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. minagao@radiol.med.kyushu-u.ac.jp.
authors.forename: Michinobu
authors.initials: M
authors.lastname: Nagao
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. tora0228@radiol.med.kyushu-u.ac.jp.
authors.forename: Torahiko
authors.initials: T
authors.lastname: Yamanouchi
authors.affiliation: Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. h-yabu@med.kyushu-u.ac.jp.
authors.forename: Hidetake
authors.initials: H
authors.lastname: Yabuuchi
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. nakam@radiol.med.kyushu-u.ac.jp.
authors.forename: Katsumasa
authors.initials: K
authors.lastname: Nakamura
authors.affiliation: Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. nakatora@qent.med.kyushu-u.ac.jp.
authors.forename: Torahiko
authors.initials: T
authors.lastname: Nakashima
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, Japan. honda@radiol.med.kyushu-u.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Honda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D054893:Cone-Beam Computed Tomography; D003287:Contrast Media; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D007479:Iopamidol; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009389:Neovascularization, Pathologic; D012189:Retrospective Studies; D014059:Tongue / Q000098:blood supply* / Q000473:pathology*; D014062:Tongue Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D003287:Contrast Media; D007479:Iopamidol
keywords: Arterial intervention; Cancer; Clinical practice ; Interventional oncology; Intraarterial