title: Dietary supplemental vitamin B6 increases carnosine and anserine concentrations in the heart of rats.
abstract: This study was performed to examine the effect of dietary level of vitamin B6 on the concentrations of carnosine and anserine, antioxidants, in the heart of rats. Analysis using UPLC-MS/MS showed that the concentrations of these dipeptides in the 7 and 35 mg pyridoxine HCl/kg groups were significantly higher than those in the 1 mg pyridoxine HCl/kg group, implying the novel role of dietary vitamin B6 as a determinant of the dipeptides favorable for heart.
authors.affiliation: Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima, 739-8528 Japan.
authors.forename: Sofya
authors.initials: S
authors.lastname: Suidasari
authors.affiliation: Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima, 739-8528 Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Hasegawa
authors.affiliation: Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima, 739-8528 Japan.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Yanaka
authors.affiliation: Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima, 739-8528 Japan.
authors.forename: Norihisa
authors.initials: N
authors.lastname: Kato
keywords: Anserine; Carnosine; Heart; UPLC–MS/MS; Vitamin B6