title: A versatile x-ray microtomography station for biomedical imaging and materials research.
abstract: An x-ray microtomography station implemented at the X-ray Applied Crystallography Laboratory of the State University of Campinas is described. The station is based on a propagation based phase contrast imaging setup with a microfocus source and digital x-ray area detectors. Due to its simplicity, this setup is ideal for fast, high resolution imaging and microtomography of small biological specimens and materials research samples. It can also be coupled to gratings to use and develop new techniques as the harmonic spatial coherent imaging, which allow scattering contrast imaging. Details of the experimental setup, equipment, and software integration are described. Test microtomography for setup commissioning and characterization is shown. We conclude that phase contrast enhanced x-ray imaging and microtomography with resolution below 5 μm voxel size are possible and data sets as wide as 2000 × 2000 × 2000 voxels are obtained with this instrumentation.
authors.affiliation: Instituto de Física "Gleb Wataghin," Universidade Estadual de Campinas, Campinas, São Paulo 13083-859, Brazil.
authors.forename: Fernando Cesar
authors.initials: FC
authors.lastname: Lussani
authors.affiliation: Instituto de Física "Gleb Wataghin," Universidade Estadual de Campinas, Campinas, São Paulo 13083-859, Brazil.
authors.forename: Rafael Ferreira da Costa
authors.initials: RF
authors.lastname: Vescovi
authors.affiliation: Instituto de Física "Gleb Wataghin," Universidade Estadual de Campinas, Campinas, São Paulo 13083-859, Brazil.
authors.forename: Thaís Diniz
authors.initials: TD
authors.lastname: de Souza
authors.affiliation: Instituto de Física "Gleb Wataghin," Universidade Estadual de Campinas, Campinas, São Paulo 13083-859, Brazil.
authors.forename: Carlos A P
authors.initials: CA
authors.lastname: Leite
authors.affiliation: Instituto de Física "Gleb Wataghin," Universidade Estadual de Campinas, Campinas, São Paulo 13083-859, Brazil.
authors.forename: Carlos
authors.initials: C
authors.lastname: Giles
mesh_terms: D000162:Acoustics; D018647:Amber; D000818:Animals; D002516:Ceramics; D004867:Equipment Design; D005269:Femur / Q000000981:diagnostic imaging; D005580:Fossils / Q000000981:diagnostic imaging; D020062:Heteroptera / Q000033:anatomy & histology; D021621:Imaging, Three-Dimensional / Q000295:instrumentation / Q000379:methods; D008858:Microscopy, Phase-Contrast / Q000295:instrumentation / Q000379:methods; D011817:Rabbits; D014025:Titanium; D014934:Wood; D055114:X-Ray Microtomography / Q000295:instrumentation* / Q000379:methods; D014965:X-Rays
chemical_list: D018647:Amber; C009495:titanium dioxide; D014025:Titanium