title: Thyroid Storm with Heart Failure Treated with a Short-acting Beta-adrenoreceptor Blocker, Landiolol Hydrochloride.
abstract: Beta-adrenoreceptor blockers are essential in controlling the peripheral actions of thyroid hormones and a rapid heart rate in patients with thyroid storm, although they should be used with great caution when there is the potential for heart failure. A 67-year-old woman was diagnosed as having thyroid storm in addition to marked tachycardia with atrial fibrillation and heart failure associated with a reduced left ventricular function. The administration of an oral beta blocker, bisoprolol fumarate, induced hypotension and was not tolerable for the patient, whereas landiolol hydrochloride, a short-acting intravenous beta-adrenoreceptor blocker with high cardioselectivity and a short elimination half-life, was useful for controlling the patient's tachycardia and heart failure without causing hemodynamic deterioration.
authors.affiliation: Department of Cardiology, National Hospital Organization Kyoto Medical Center, Japan.
authors.forename: Yugo
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Moritake
authors.initials: M
authors.lastname: Iguchi
authors.forename: Rieko
authors.initials: R
authors.lastname: Nakatani
authors.forename: Takeshi
authors.initials: T
authors.lastname: Usui
authors.forename: Daisuke
authors.initials: D
authors.lastname: Takagi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hamatani
authors.forename: Takashi
authors.initials: T
authors.lastname: Unoki
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Ishii
authors.forename: Hisashi
authors.initials: H
authors.lastname: Ogawa
authors.forename: Nobutoyo
authors.initials: N
authors.lastname: Masunaga
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Abe
authors.forename: Masaharu
authors.initials: M
authors.lastname: Akao
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000368:Aged; D001281:Atrial Fibrillation / Q000503:physiopathology; D004554:Electric Countershock; D005260:Female; D006333:Heart Failure / Q000503:physiopathology / Q000517:prevention & control*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007262:Infusions, Intravenous; D009025:Morpholines / Q000627:therapeutic use*; D013610:Tachycardia / Q000209:etiology; D013958:Thyroid Crisis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D013965:Thyroidectomy / Q000379:methods; D016896:Treatment Outcome; D014508:Urea / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D009025:Morpholines; C077049:landiolol; D014508:Urea