title: Endovascular Repair of Descending Thoracic Aorta in Loeys-Dietz II Syndrome.
abstract: Loeys-Dietz syndrome (LDS) is an autosomal dominant disorder that is predominantly characterized by involvement of the aorta, manifesting as aneurysmal dilatation or aortic dissection. Patients with LDS manifest with spontaneous aneurysms and dissections of central and peripheral arterial beds. We present 2 cases of young male patients with Loeys-Dietz II aortopathy, who manifested with spontaneous intimal tear of descending thoracic aorta and contained aortic rupture. Both patients were managed by endovascular repair, with collaborative efforts of teams comprising interventional cardiologists and radiologists, and a vascular surgeon.
authors.affiliation: Division of Cardiovascular Medicine, Minneapolis Heart Institute - Abbott Northwestern Hospital, Minneapolis, MN.
authors.forename: Ankur
authors.initials: A
authors.lastname: Kalra
authors.affiliation: Division of Cardiovascular Medicine, Minneapolis Heart Institute - Abbott Northwestern Hospital, Minneapolis, MN. Electronic address: kharris@mplsheart.com.
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Harris
authors.affiliation: Heart Center Rostock, University Hospital Rostock, Rostock School of Medicine, Rostock, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Kische
authors.affiliation: Division of Vascular Surgery, Minneapolis Heart Institute - Abbott Northwestern Hospital, Minneapolis, MN.
authors.forename: Peter
authors.initials: P
authors.lastname: Alden
authors.affiliation: Division of Interventional Radiology, Minneapolis Heart Institute - Abbott Northwestern Hospital, Minneapolis, MN.
authors.forename: Clark
authors.initials: C
authors.lastname: Schumacher
authors.affiliation: Heart Center Rostock, University Hospital Rostock, Rostock School of Medicine, Rostock, Germany.
authors.forename: Christoph A
authors.initials: CA
authors.lastname: Nienaber
mesh_terms: D000328:Adult; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis / Q000601:surgery*; D001027:Aortography / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation; D003299:Cooperative Behavior; D057510:Endovascular Procedures; D006801:Humans; D033183:Interdisciplinary Communication; D055947:Loeys-Dietz Syndrome / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D010348:Patient Care Team; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional