title: [Modern pathogenetic aspects of development of cerebral chronic ischemia].
abstract: Key mechanisms of the development of cerebral blood circulation insufficiency are presented. The following initial patters are analyzed: primary cytokine response, endothelial dysfunction and functioning of neurovascular units. Current conceptions on the development of pathological apoptosis and neuroplasticity are considered.
authors.affiliation: Pirogov Russian National Research Medical University, Moscow.
authors.forename: E I
authors.initials: EI
authors.lastname: Gusev
authors.affiliation: Pirogov Russian National Research Medical University, Moscow.
authors.forename: A S
authors.initials: AS
authors.lastname: Chukanova
mesh_terms: D017209:Apoptosis; D002545:Brain Ischemia / Q000473:pathology* / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D006801:Humans; D008297:Male; D009473:Neuronal Plasticity