title: [Detection and grading of endolymphatic hydrops in Ménière's disease using 3D FLAIR MRI].
abstract: OBJECTIVE
  To evaluate the extent of endolymphatic hydrops as shown by three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D FLAIR MRI) performed 24 hours after bilateral intratympanic gadolinium administration and discuss the positive rate of endolymphatic hydrops in vestibule and cochlea.
  
  
  METHODS
  Twenty-four hours after bilateral intra-tympanic 8 times diluted gadolinium administration, three-dimensional fluid-attenuated inversion recovery MRI, using a three-Tesla unit, was performed in 48 patients, and then assessed the extent of endolymphatic hydrops in the MRI images.
  
  
  RESULTS
  Forty-eight patients showed different levels of enhancement of perilymth in the inner ear. In these patients, obvious signs of endolymphatic hydrops were visualized in vestibule,including 8 slight hydrops, 17 mild hydrops and 23 severe hydrops with a diagnostic rate of 83.3%. There were almost no complications in all 48 patients after bilateral intra-tympanic injection except short vertigo in some of them.
  
  
  CONCLUSIONS
  3D FLAIR MRI resonance imaging has a high positive diagnostic rate in assessing endolymphatic hydrops of Ménière's disease and provides direct imaging evidence for diagnosing Ménière's disease.
authors.forename: Jin
authors.initials: J
authors.lastname: Yan
authors.forename: Liyan
authors.initials: L
authors.lastname: Peng
authors.forename: Hongzheng
authors.initials: H
authors.lastname: Cheng
authors.forename: Yonghua
authors.initials: Y
authors.lastname: Cui
authors.forename: Aiguo
authors.initials: A
authors.lastname: Liu
mesh_terms: D003051:Cochlea; D003287:Contrast Media; D007758:Ear, Inner; D004432:Ear, Middle; D019786:Gadolinium DTPA; D006801:Humans; D021621:Imaging, Three-Dimensional; D007267:Injections; D008279:Magnetic Resonance Imaging; D008575:Meniere Disease / Q000175:diagnosis*; D014722:Vestibule, Labyrinth
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA