title: Adenocarcinoma arising at ileostomy sites: Two cases and a review of the literature.
abstract: Total colectomy with ileostomy placement is a treatment for patients with inflammatory bowel disease or familial adenomatous polyposis (FAP). A rare and late complication of this treatment is carcinoma arising at the ileostomy site. We describe two such cases: a 78-year-old male 30 years after subtotal colectomy and ileostomy for FAP, and an 85-year-old male 50 years after colectomy and ileostomy for ulcerative colitis. The long latency period between creation of the ileostomies and development of carcinoma suggests a chronic metaplasia due to an irritating/inflammatory causative factor. Surgical excision of the mass and relocation of the stoma is the mainstay of therapy, with possible benefits from adjuvant chemotherapy. Newly developed lesions at stoma sites should be biopsied to rule out the possibility of this rare ileostomy complication.
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Lauren
authors.initials: L
authors.lastname: Procaccino
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Sameer
authors.initials: S
authors.lastname: Rehman
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Alexander
authors.initials: A
authors.lastname: Abdurakhmanov
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Peter
authors.initials: P
authors.lastname: McWhorter
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Nicholas
authors.initials: N
authors.lastname: La Gamma
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Madhu C
authors.initials: MC
authors.lastname: Bhaskaran
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: James
authors.initials: J
authors.lastname: Maurer
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Grimaldi
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Horacio
authors.initials: H
authors.lastname: Rilo
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Nicastro
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Gene
authors.initials: G
authors.lastname: Coppa
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: Ernesto P
authors.initials: EP
authors.lastname: Molmenti
authors.affiliation: Lauren Procaccino, Sameer Rehman, Alexander Abdurakhmanov, Peter McWhorter, Nicholas La Gamma, Madhu C Bhaskaran, James Maurer, Gregory M Grimaldi, Horacio Rilo, Jeffrey Nicastro, Gene Coppa, Ernesto P Molmenti, John Procaccino, Department of Surgery, North Shore University Hospital, Manhasset, NY 11030, United States.
authors.forename: John
authors.initials: J
authors.lastname: Procaccino
keywords: Adenocarcinoma; Carcinoma; Complication of ileostomy; Familial adenomatous polyposis; Ileostomy; Inflammatory bowel disease