title: Level of perioperative B-type natriuretic peptide associates with heart function after on-pump coronary artery bypass graft surgery on a beating heart.
abstract: OBJECTIVE
  To explore the relationship of the perioperative B-type natriuretic peptide (BNP) level with heart function among patients undergoing on-pump coronary artery bypass graft surgery on a beating heart.
  
  
  METHODS
  Total 90 patients expected to undergo coronary artery bypass graft surgery were selected and their left ventricular ejection fraction (LVEF) were examined before operation. Patients with LVEF greater than or equal to 50% were selected as the A group (n=46), and those less than 50% formed the B group (n=44). BNP levels of the patients were examined and its relationship with cardiac function was analyzed.
  
  
  RESULTS
  BNP levels of group A was lower than that in group B pre-and post-operatively (until 7 days after the surgery), the difference is statistically significant (p<0.05). Pearson analysis showed that the BNP level was negatively correlated with the LVEF (r = 0.767, p< 0.05). The area under the Roc curve is 0.865.
  
  
  CONCLUSIONS
  BNP level was negatively correlated with the LVEF. Perioperative BNP level can be used as the prediction for heart function of patients with on-pump coronary artery bypass graft surgery on a beating heart.
authors.affiliation: Baocai Wang, Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Henan Cardiovascular Disease Institute, Zhengzhou 450003, P.R. China.
authors.forename: Baocai
authors.initials: B
authors.lastname: Wang
authors.affiliation: Zhaoyun Cheng, Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Henan Cardiovascular Disease Institute, Zhengzhou 450003, P.R. China.
authors.forename: Zhaoyun
authors.initials: Z
authors.lastname: Cheng
authors.affiliation: Zhenwei Ge, Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Henan Cardiovascular Disease Institute, Zhengzhou 450003, P.R. China.
authors.forename: Zhenwei
authors.initials: Z
authors.lastname: Ge
authors.affiliation: Bangtian Peng, Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Henan Cardiovascular Disease Institute, Zhengzhou 450003, P.R. China.
authors.forename: Bangtian
authors.initials: B
authors.lastname: Peng
authors.affiliation: Ziniu Zhao, Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Henan Cardiovascular Disease Institute, Zhengzhou 450003, P.R. China.
authors.forename: Ziniu
authors.initials: Z
authors.lastname: Zhao
authors.affiliation: Xiaoqiang Quan, Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Henan Cardiovascular Disease Institute, Zhengzhou 450003, P.R. China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Quan
keywords: B-type natriuretic peptide; Cardiac function; On-pump coronary artery bypass surgery; Perioperative