title: [Infantile myofibroma: a neonate with a swelling on the arm].
abstract: BACKGROUND
  An infantile myofibroma (IM) is a benign congenital soft-tissue tumour. IM is found in 1 per 150,000 live births, making it the most common fibrous tumour of infancy and early childhood.
  
  
  METHODS
  We report on a full-term neonate presenting with an irregular tumour mass on the right lower-arm. The mass measured 5 cm in diameter, with surface ulceration. Magnetic resonance imaging (MRI) revealed characteristics that could be consistent with malignancy. On the basis of a biopsy and subsequent polymerase chain reaction we were able to make a diagnosis of 'benign infantile myofibroma'. We chose for conservative treatment in the expectation that the tumour would regress spontaneously.
  
  
  CONCLUSIONS
  Infantile myofibroma should be considered when a newborn presents with an atypical mass. It is difficult to make a diagnosis on the basis of the clinical characteristics alone due to the heterogeneous presentation. A definitive diagnosis can only be made following histological investigation.
authors.affiliation: Radboudumc, Nijmegen.
authors.forename: Lindy N M
authors.initials: LN
authors.lastname: Gommans
authors.forename: Laura G
authors.initials: LG
authors.lastname: Spring in 't Veld
authors.forename: Mayke E
authors.initials: ME
authors.lastname: van der Putten
authors.forename: Marc H W A
authors.initials: MH
authors.lastname: Wijnen
mesh_terms: D001132:Arm / Q000473:pathology*; D001706:Biopsy; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D047708:Myofibroma / Q000175:diagnosis*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis*