title: Emerging Trends in Abdominal Wall Reinforcement: Bringing Bio-Functionality to Meshes.
abstract: Abdominal wall hernia is a recurrent issue world-wide and requires the implantation of over 1 million meshes per year. Because permanent meshes such as polypropylene and polyester are not free of complications after implantation, many mesh modifications and new functionalities have been investigated over the last decade. Indeed, mesh optimization is the focus of intense development and the biomaterials utilized are now envisioned as being bioactive substrates that trigger various physiological processes in order to prevent complications and to promote tissue integration. In this context, it is of paramount interest to review the most relevant bio-functionalities being brought to new meshes and to open new avenues for the innovative development of the next generation of meshes with enhanced properties for functional abdominal wall hernia repair.
authors.affiliation: Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstraße 13, A-1200, Vienna, Austria.|Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, A-1200, Vienna, Austria.
authors.forename: Olivier
authors.initials: O
authors.lastname: Guillaume
authors.affiliation: Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, A-1200, Vienna, Austria.|University of Applied Sciences Technikum Wien, Department of Biochemical Engineering, Höchstädtplatz 5, 1200, Vienna, Austria.
authors.forename: Andreas Herbert
authors.initials: AH
authors.lastname: Teuschl
authors.affiliation: Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstraße 13, A-1200, Vienna, Austria.|Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, A-1200, Vienna, Austria.|Department of General Visceral and Oncological Surgery, Wilhelminenspital der Stadt Wien, Montleartstraße 37, A-1171, Vienna, Austria.
authors.forename: Simone
authors.initials: S
authors.lastname: Gruber-Blum
authors.affiliation: Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, A-1200, Vienna, Austria.|Department of General Visceral and Oncological Surgery, Wilhelminenspital der Stadt Wien, Montleartstraße 37, A-1171, Vienna, Austria.
authors.forename: René Hartmann
authors.initials: RH
authors.lastname: Fortelny
authors.affiliation: Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstraße 13, A-1200, Vienna, Austria.|Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, A-1200, Vienna, Austria.
authors.forename: Heinz
authors.initials: H
authors.lastname: Redl
authors.affiliation: Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstraße 13, A-1200, Vienna, Austria.|Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, A-1200, Vienna, Austria.
authors.forename: Alexander
authors.initials: A
authors.lastname: Petter-Puchner
mesh_terms: D034861:Abdominal Wall / Q000601:surgery*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000494:pharmacology; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D004195:Disease Models, Animal; D006555:Hernia, Ventral / Q000601:surgery*; D006801:Humans; D011091:Polyesters / Q000737:chemistry; D011126:Polypropylenes / Q000737:chemistry; D019736:Prostheses and Implants; D013526:Surgical Mesh
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D020099:Coated Materials, Biocompatible; D011091:Polyesters; D011126:Polypropylenes
keywords: cells; coating; drug delivery systems; hernias; meshes