title: Clinical significance of joint detection of mALB and NAG for early kidney damage in burn patients.
abstract: BACKGROUND
  The aim of this study was to study the clinical significance of joint detection of mALB and NAG in early kidney damage in burn patients.
  
  
  METHODS
  Forty-five burn patients of different degrees were selected and divided into mild, moderate, severe, and heavy burns, and normal healthy controls according to their severity. Their b2- macroglobulin (b2-MG), a1-macroglobulin (a1-MG), mALB and N-acetyl-b-D-NAG were tested for 3 days, 1 week, 2 weeks, 4 weeks after the burn, respectively.
  
  
  RESULTS
  The urine concentration change b2-MG, a1-MG, MALB, and NAG are related to the area, depth and degree of the burn. The more serious the burn is, the higher the levels of mALB and NAG (P<0.001 or P<0.01) is.
  
  
  CONCLUSIONS
  Early detection of mALB and NAG is helpful for early kidney damage diagnosis in burn patients to prevent further complications.
authors.affiliation: Department of Plastic Surgery at the Xuzhou Central Hospital, Xuzhou, China - djicun@126.com.
authors.forename: Ji C
authors.initials: JC
authors.lastname: Ding
authors.forename: Zhong L
authors.initials: ZL
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000652:urine; D002056:Burns / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism / Q000652:urine*; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000652:urine*; D011237:Predictive Value of Tests; D011379:Prognosis; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D048809:alpha-N-Acetylgalactosaminidase / Q000652:urine*
chemical_list: D015415:Biomarkers; C117339:NBAS protein, human; D009363:Neoplasm Proteins; D048809:alpha-N-Acetylgalactosaminidase