title: Pelvic Ependymoma With Clinical Response to GnRH Analog Therapy: A Case Report With an Overview of Primary Extraneural Ependymomas.
abstract: Extraneural ependymomas are rare tumors that occur in sacrococcygeal, pelvic and extra pelvic regions. While sacrococcygeal extraneural ependymomas are equally distributed among males and females, pelvic and extra pelvic ependymomas have been exclusively reported in women, mainly of child bearing age. We present a case of extraneural, pelvic ependymoma that showed clinical response to GnRH therapy with its immunohistochemical and electron microscopic analysis, and an overview of primary extraneural ependymomas based on a review of all such cases published in English literature.
authors.affiliation: Departments of Pathology (F.Z.) Obstretrics and Gynecology (J.S.) Neuropathology (I.M.) Gynecologic Pathology (P.S.), New York University School of Medicine Department of Pathology (M.R.), Memorial Sloan Kettering Cancer Center, New York, New York.
authors.forename: Fang
authors.initials: F
authors.lastname: Zhou
authors.forename: Joon
authors.initials: J
authors.lastname: Song
authors.forename: Irina
authors.initials: I
authors.lastname: Mikolaenko
authors.forename: Marc
authors.initials: M
authors.lastname: Rosenblum
authors.forename: Pratibha S
authors.initials: PS
authors.lastname: Shukla
mesh_terms: D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D015820:Cadherins / Q000032:analysis; D004806:Ependymoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D016729:Leuprolide / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008854:Microscopy, Electron; D010388:Pelvis; D011944:Receptors, Androgen / Q000032:analysis; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D018931:Antineoplastic Agents, Hormonal; D015820:Cadherins; D005904:Glial Fibrillary Acidic Protein; D011944:Receptors, Androgen; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D007633:Keratins; D016729:Leuprolide