title: Pertussis Prevalence in Korean Adolescents and Adults with Persistent Cough.
abstract: We investigated the prevalence of pertussis in Korean adolescents and adults with persistent cough. Study population was adolescents (aged 11-20 yr) and adults (≥ 21 yr old) who showed persistent cough of 1-8 weeks' duration. Pertussis was diagnosed by culture, polymerase chain reaction (PCR), and serology. A total of 310 subjects participated in this study, and 76 cases (24.5%) met the criteria for laboratory-confirmed pertussis. The majority of the pertussis cases (66/76) were confirmed by serology, while 3 cases (1.0%) were diagnosed with culture, and 10 cases (3.2%) were detected with PCR. Of the 76 subjects diagnosed with pertussis, 20/86 cases were adolescents and 56/224 cases were adults. Neither adolescents nor adults received adolescent-adult booster against pertussis within the previous 5 yr. Pertussis can be a primary cause of persistent cough in Korean adolescents and adults.
authors.affiliation: Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. ; Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Soo Young
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. ; Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Seung Beom
authors.initials: SB
authors.lastname: Han
authors.affiliation: Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea. ; Vaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Jin Han
authors.initials: JH
authors.lastname: Kang
authors.affiliation: Department of Pulmonology, The Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Korea.
authors.forename: Ju Sang
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D001886:Bordetella pertussis / Q000276:immunology; D002648:Child; D003371:Cough / Q000453:epidemiology*; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000276:immunology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007117:Immunization, Secondary / Q000706:statistics & numerical data*; D008297:Male; D056910:Republic of Korea / Q000453:epidemiology; D014917:Whooping Cough / Q000453:epidemiology* / Q000276:immunology; D055815:Young Adult
chemical_list: D015721:Diphtheria-Tetanus-Pertussis Vaccine
keywords: Adolescent; Adult; Cough; Korea; Pertussis