title: From Grey Scale B-Mode to Elastosonography: Multimodal Ultrasound Imaging in Meningioma Surgery-Pictorial Essay and Literature Review.
abstract: The main goal in meningioma surgery is to achieve complete tumor removal, when possible, while improving or preserving patient neurological functions. Intraoperative imaging guidance is one fundamental tool for such achievement. In this regard, intra-operative ultrasound (ioUS) is a reliable solution to obtain real-time information during surgery and it has been applied in many different aspect of neurosurgery. In the last years, different ioUS modalities have been described: B-mode, Fusion Imaging with pre-operative acquired MRI, Doppler, contrast enhanced ultrasound (CEUS), and elastosonography. In this paper, we present our US based multimodal approach in meningioma surgery. We describe all the most relevant ioUS modalities and their intraoperative application to obtain precise and specific information regarding the lesion for a tailored approach in meningioma surgery. For each modality, we perform a review of the literature accompanied by a pictorial essay based on our routinely use of ioUS for meningioma resection.
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy.
authors.forename: Francesco
authors.identifier: 0000-0003-0653-9317
authors.initials: F
authors.lastname: Prada
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy.
authors.forename: Massimiliano
authors.identifier: 0000-0002-6672-9721
authors.initials: M
authors.lastname: Del Bene
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy ; University of Milan, 20122 Milan, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Moiraghi
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Casali
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy.
authors.forename: Federico Giuseppe
authors.initials: FG
authors.lastname: Legnani
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy.
authors.forename: Andrea
authors.identifier: 0000-0002-6439-6556
authors.initials: A
authors.lastname: Saladino
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Perin
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy ; University of Milan, 20122 Milan, Italy.
authors.forename: Ignazio Gaspare
authors.identifier: 0000-0003-0664-9700
authors.initials: IG
authors.lastname: Vetrano
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy ; University of Milan, 20122 Milan, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Mattei
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy ; University of Milan, 20122 Milan, Italy.
authors.forename: Carla
authors.initials: C
authors.lastname: Richetta
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Saini
authors.affiliation: Department of Neurosurgery, IRCCS Foundation Neurological Institute "C. Besta", 20133 Milan, Italy ; Department of Neurosurgery, Johns Hopkins University, Baltimore, MD 21218, USA.
authors.forename: Francesco
authors.identifier: 0000-0001-6213-5793
authors.initials: F
authors.lastname: DiMeco
mesh_terms: D003287:Contrast Media; D054459:Elasticity Imaging Techniques; D019220:High-Energy Shock Waves; D006801:Humans; D007432:Intraoperative Period; D008279:Magnetic Resonance Imaging; D008579:Meningioma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D019635:Neurosurgical Procedures; D018084:Ultrasonography, Interventional / Q000379:methods*
chemical_list: D003287:Contrast Media