title: Thermal necrosis induced by electrocauterization as a local adjuvant therapy in local aggressive bone tumors, what is the safe limit for surgical margins? An experimental study.
abstract: OBJECTIVE
  In the current study, it was aimed to investigate the temperature change in the cavity wall and pathologic necrosis occurred during cauterization, which was applied at different voltages and time intervals.
  
  
  METHODS
  The right tibias of 32 male rabbits were used. Three 2-mm-diameter holes were created on the cortical surface of the tibia using a hand-held drill. Using an electrocautery device, 55 mV was applied for 3 and 5 s and 65 mV was applied for 3 and 5 s. Maximum temperatures at 3 and 6 mm distance from the application site were measured. Biopsy specimens obtained at 3 and 6 mm distance from the application site were evaluated microscopically for bone cell viability and periosteal necrosis.
  
  
  RESULTS
  Thirty-two rabbits were divided into four groups. In all groups, periosteal bone cells located at the region, extending from the application site to 3 mm distance, died. In this region, application of 55 mV for 3 s caused peripheral necrosis. There were significant differences between the four groups in terms of maximum temperatures measured at 3 mm distance from the application site (p = 0.027). On the other hand, no significant differences were noted between the four groups in terms of maximum temperatures measured at 6 mm distance from the application site (p > 0.05).
  
  
  CONCLUSIONS
  Cauterization of the cavity wall in the spray mode at 55 mV for 3 s after tumor resection caused necrosis in the cavity wall, extending from the application site to 3 mm distance.
  
  
  METHODS
  Experimental animal study, Level II.
authors.affiliation: Department of Orthopedics and Traumatology, Afyonkarahisar Suhut Public Hospital Medicine, Afyonkarahisar, Turkey, opr.murataydin@gmail.com.
authors.forename: Murat
authors.initials: M
authors.lastname: Aydin
authors.forename: Kerem
authors.initials: K
authors.lastname: Basarir
authors.forename: Mehmet
authors.initials: M
authors.lastname: Armangil
authors.forename: Huseyin Yusuf
authors.initials: HY
authors.lastname: Yildiz
authors.forename: Yener
authors.initials: Y
authors.lastname: Saglik
authors.forename: Hasan
authors.initials: H
authors.lastname: Bilgili
authors.forename: Nihat
authors.initials: N
authors.lastname: Yumusak
mesh_terms: D000818:Animals; D001859:Bone Neoplasms / Q000473:pathology*; D004564:Electrocoagulation / Q000379:methods*; D008297:Male; D023421:Models, Animal; D009336:Necrosis; D010521:Periosteum / Q000473:pathology; D011817:Rabbits; D013977:Tibia / Q000473:pathology* / Q000601:surgery*