title: Conformational and Chiral Properties of Cyclic-tri(N-methyl-meta-benzamide) Bearing Amidino Groups.
abstract: Cyclic triamides bearing amidino groups at the meta position of the phenyl rings were synthesized, and their conformational properties in the crystal and in solution were examined. Compound exists as a capsule-type dimer of the enantiomers with a bowl-shaped syn conformation in the crystal state. Compound exists mainly in the syn form in solution, and chiral induction was observed upon addition of a chiral acid to a solution of.
authors.affiliation: Department of Chemistry, Faculty of Science, Ochanomizu University, Tokyo, Japan.
authors.forename: Shizuka
authors.initials: S
authors.lastname: Nishiyama
authors.affiliation: Department of Chemistry, Faculty of Science, Ochanomizu University, Tokyo, Japan.
authors.forename: Ko
authors.initials: K
authors.lastname: Urushibara
authors.affiliation: Center for Analytical Instrumentation, Chiba University, Chiba, Japan.
authors.forename: Hyuma
authors.initials: H
authors.lastname: Masu
authors.affiliation: Faculty of Pharmaceutical Sciences, Toho University, Chiba, Japan.
authors.forename: Isao
authors.initials: I
authors.lastname: Azumaya
authors.affiliation: Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kagechika
authors.affiliation: Department of Chemistry, Faculty of Science, Ochanomizu University, Tokyo, Japan.
authors.forename: Aya
authors.initials: A
authors.lastname: Tanatani
mesh_terms: D000578:Amidines / Q000737:chemistry; D001549:Benzamides / Q000737:chemistry*; D008968:Molecular Conformation; D013237:Stereoisomerism
chemical_list: D000578:Amidines; D001549:Benzamides
keywords: chiral induction; crystal structure; cyclic amide; dimer, capsule