title: Radiation-induced meningiomas after BNCT in patients with malignant glioma.
abstract: Of the 180 patients with malignant brain tumors whom we treated with boron neutron capture therapy (BNCT) since 1968, only one (0.56%) developed multiple radiation-induced meningiomas. The parasagittal meningioma that had received 42 Gy (w) for BNCT showed more rapid growth on Gd-enhanced MRI scans and more atypical features on histopathologic studies than the temporal convexity tumor that had received 20 Gy (w). Long-term follow up MRI studies are necessary in long-survivors of malignant brain tumors treated by BNCT.
authors.affiliation: Department of Neurosurgery, The University of Tokushima, Tokushima, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kageji
authors.affiliation: Department of Neurosurgery, The University of Tokushima, Tokushima, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Sogabe
authors.affiliation: Department of Neurosurgery, The University of Tokushima, Tokushima, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Mizobichi
authors.affiliation: Department of Neurosurgery, The University of Tokushima, Tokushima, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.affiliation: Department of Neurosurgery, The University of Tokushima, Tokushima, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Shinji
authors.affiliation: Department of Neurosurgery, Shikoku Medical Center for Children and Adults, Kagawa, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Nakagawa
mesh_terms: D016754:Boron Neutron Capture Therapy / Q000009:adverse effects*; D001932:Brain Neoplasms / Q000532:radiotherapy*; D005909:Glioblastoma / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008579:Meningioma / Q000209:etiology*; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*
keywords: BNCT; Meningioma; Radiation-induced tumor