title: [Cerebrospinal fluid in clinical aspects of tuberculosis of the central nervous system].
abstract: OBJECTIVE
  To identify clinical features of tuberculosis of the meninges and central nervous system (TM) with detailed characterization of changes in the composition of cerebrospinal fluid (CSF) in the initial period of the disease.
  
  
  METHODS
  We analyzed the results of the examination of 42 patients, aged from 17 to 49 years, who were hospitalized in 2005-2014.
  
  
  CONCLUSIONS
  Most of the patients were admitted in the hospital in early acute disease onset. Along with the description of inflectional and cerebral symptoms, meningeal signs, disorders of consciousness and focal symptoms, we presented cell count values, protein and glucose concentrations at initial examination of CSF as well as the results of additional examination and specific therapy issues. The importance of combining treatment standards and individualization of therapy of TM patients is emphasized.
authors.affiliation: Chumakov Institute of Poliomielitis and Viral Encephalitic, Russian Academy of Sciences, Moscow.
authors.forename: A S
authors.initials: AS
authors.lastname: Shyshov
authors.affiliation: Infectious clinical hospital #1, Moscow.
authors.forename: I S
authors.initials: IS
authors.lastname: Petrova
authors.affiliation: Moscow Scientific and Practical Center of Tuberculosis Control, Moscow.
authors.forename: T P
authors.initials: TP
authors.lastname: Grishina
authors.affiliation: Moscow Scientific and Practical Center of Tuberculosis Control, Moscow.
authors.forename: K S
authors.initials: KS
authors.lastname: Frolova
authors.affiliation: Infectious clinical hospital #1, Moscow.
authors.forename: I A
authors.initials: IA
authors.lastname: Blank
authors.affiliation: Tuberculosis Dispensary #13, Moscow.
authors.forename: A B
authors.initials: AB
authors.lastname: Inozemtseva
authors.affiliation: Infectious clinical hospital #1, Moscow.
authors.forename: S A
authors.initials: SA
authors.lastname: Rusanova
authors.affiliation: Infectious clinical hospital #1, Moscow.
authors.forename: O E
authors.initials: OE
authors.lastname: Ambrosy
mesh_terms: D000293:Adolescent; D000328:Adult; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000166:cytology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020306:Tuberculosis, Central Nervous System / Q000134:cerebrospinal fluid*; D014390:Tuberculosis, Meningeal / Q000134:cerebrospinal fluid; D055815:Young Adult