title: Nodular trachea: tracheobronchopathia osteochondroplastica.
abstract: Tracheobronchopathia osteochondroplastica (TPO) is a rare disorder characterised by development of cartilaginous and bony nodules in the trachea. It usually affects elderly males with total prevalence of disease reported to be around 0.1%. Even though multiple theories and associations have been described, the exact cause of the disease remains unknown. Its presentation is non-specific with many cases being diagnosed incidentally. Chronic cough and dyspnoea are the most common presenting symptoms, but some cases may present with severe airway compromise. We present a case of a 70-year-old man with IgA λ multiple myeloma, who was diagnosed with TPO by flexible bronchoscopy.
authors.affiliation: Cooper University Hospital, Camden, New Jersey, USA.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Jagpal
authors.initials: J
authors.lastname: Klair
authors.affiliation: Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Joiner
authors.affiliation: Department of Pulmonary and Critical Care Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Nikhil K
authors.initials: NK
authors.lastname: Meena
mesh_terms: D000368:Aged; D001999:Bronchoscopy; D003371:Cough / Q000175:diagnosis* / Q000209:etiology; D004417:Dyspnea / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000150:complications; D010009:Osteochondrodysplasias / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D035583:Rare Diseases; D012131:Respiratory Insufficiency / Q000175:diagnosis* / Q000209:etiology; D014132:Trachea / Q000473:pathology*; D014133:Tracheal Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology