title: Longitudinal evaluation of 100% fruit juice consumption on BMI status in 2-5-year-old children.
abstract: Obesity in childhood is related to multiple lifestyle factors. Our objective was to evaluate the relationship between consumption of 100% fruit juice and weight status over time among pre-school children.
  
  
  
  We used linear and logistic multivariable regression to evaluate body mass index (BMI) z-score and overweight/obese status as a function of 100% fruit juice intake for 8950 children examined at ages 2, 4 and 5 years as part of the Early Childhood Longitudinal Study-Birth Cohort, a representative sample of the United States.
  
  
  
  Cross-sectional analysis at ages 4 and 5 years showed no difference in the prevalence of overweight and obesity between consistent juice drinkers and inconsistent/non-drinkers. Longitudinal analysis found that children who drank 100% juice consistently at age 2 years had greater increases in BMI z-score by age 4 years than infrequent/non-drinkers (P < 0.0001), a difference driven by lesser increases in height z-score (P = 0.0003) and slightly greater increases in weight z-score (P = 0.0550) among consistent juice drinkers over the 2 to 4 year time period. Additionally, consistent juice drinkers at age 2 had higher odds of becoming overweight by age 4 (adjusted odds ratio 1.30; CI 1.06-1.60). These differences in growth parameters were not noted between ages 4 and 5 years.
  
  
  
  Drinking 100% fruit juice regularly at age 2 is associated with higher odds of becoming overweight between 2 and 4 years. Paediatricians and parents can discourage excessive fruit juice consumption as part of a larger effort to avoid unhealthy gain in BMI in young children.
authors.affiliation: Department of Pediatrics, University of Virginia, Charlottesville, VA, USA.
authors.forename: A
authors.initials: A
authors.lastname: Shefferly
authors.affiliation: Department of Pediatrics, University of Virginia, Charlottesville, VA, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Scharf
authors.affiliation: Department of Pediatrics, University of Virginia, Charlottesville, VA, USA.|Division of Pediatric Endocrinology, University of Virginia School of Medicine, Charlottesville, VA, USA.
authors.forename: M D
authors.initials: MD
authors.lastname: DeBoer
mesh_terms: D000367:Age Factors; D015992:Body Mass Index; D001835:Body Weight; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005638:Fruit; D000067030:Fruit and Vegetable Juices / Q000009:adverse effects*; D006801:Humans; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D009765:Obesity / Q000453:epidemiology; D016017:Odds Ratio; D050177:Overweight / Q000453:epidemiology; D014481:United States
keywords: fruit juice; obesity; sugar; weight gain