title: High-Flow Nasal Cannula and Aerosolized β Agonists for Rescue Therapy in Children With Bronchiolitis: A Case Series.
abstract: Asthma and bronchiolitis are episodic obstructive pulmonary diseases characterized by bronchoconstriction, airway wall inflammation, increased mucus production, and air-flow obstruction. We present the cases of 5 infants treated for acute bronchiolitis with respiratory distress using a combination of high-flow nasal cannula oxygen (HFNC) and an Aerogen nebulizer to deliver aerosolized β-agonist therapy. In all infants, we found that HFNC resulted in a greater heart rate increase than delivery via a facemask. We also found that patients tolerated inhaled therapy better with HFNC than a facemask.
authors.affiliation: Department of Respiratory Care sherwin.morgan@uchospitals.edu.
authors.forename: Sherwin E
authors.initials: SE
authors.lastname: Morgan
authors.affiliation: Department of Respiratory Care.
authors.forename: Steve
authors.initials: S
authors.lastname: Mosakowski
authors.affiliation: Department of Respiratory Care.
authors.forename: Patti
authors.initials: P
authors.lastname: Solano
authors.affiliation: Section of Pulmonary and Critical Care Medicine, Department of Medicine.
authors.forename: Jesse B
authors.initials: JB
authors.lastname: Hall
authors.affiliation: Department of Anesthesia and Critical Care, The University of Chicago, Chicago, Illinois.
authors.forename: Avery
authors.initials: A
authors.lastname: Tung
mesh_terms: D058666:Adrenergic beta-2 Receptor Agonists / Q000008:administration & dosage*; D001988:Bronchiolitis / Q000628:therapy*; D057785:Catheters; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D059085:Nasal Sprays; D009330:Nebulizers and Vaporizers; D010102:Oxygen Inhalation Therapy / Q000295:instrumentation*; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D016879:Salvage Therapy / Q000379:methods*
chemical_list: D058666:Adrenergic beta-2 Receptor Agonists; D059085:Nasal Sprays
keywords: HFNC; asthma; bronchiolitis; high-flow nasal cannula; β agonists