title: Triterpenoids from the barks of Terminalia chebula.
abstract: Two new triterpenoids, termichebuloside A (1), an unusual dimeric triterpenoid saponin, and termichebulolide (2), an oleanolic acid-type lactone, along with 11 known triterpenoids, were isolated from MeOH extract of the barks of Terminalia chebula. The structures of 1 and 2 were elucidated to be arjunglucoside I-(3-O-19',23-O-19')-18,19-seco-19-hydroxyarjunglucoside I (1) and 2α,3β,23-trihydroxyolean-11,13(18)-dien-28,19β-olide (2), respectively, on the basis of spectroscopic evidences and biogenetic consideration.
authors.affiliation: a Department of Natural Medicinal Chemistry , Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.
authors.forename: Chao
authors.initials: C
authors.lastname: Zhang
authors.affiliation: a Department of Natural Medicinal Chemistry , Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.
authors.forename: Kun
authors.initials: K
authors.lastname: Jiang
authors.affiliation: a Department of Natural Medicinal Chemistry , Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.
authors.forename: Shi-Jin
authors.initials: SJ
authors.lastname: Qu
authors.affiliation: a Department of Natural Medicinal Chemistry , Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Zhai
authors.affiliation: a Department of Natural Medicinal Chemistry , Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Tan
authors.affiliation: a Department of Natural Medicinal Chemistry , Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.
authors.forename: Chang-Heng
authors.initials: CH
authors.lastname: Tan
mesh_terms: D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism; D029766:Terminalia / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D012503:Saponins; D014315:Triterpenes; C000604769:termichebulolide; C000604768:termichebuloside A
keywords: Terminalia chebula; dimeric triterpenoid saponin; termichebulolide; termichebuloside A; triterpenoid lactone