title: Correlation analysis between single nucleotide polymorphism of DRD1 gene and stereotyped behavior of blue fox.
abstract: This study was performed to investigate the correlation between stereotyped behavior of the blue fox and single nucleotide polymorphisms (SNPs) of the DRD1 gene. We choose the DRD1 gene as a major gene for investigating the correlation of gene polymorphism and self-biting disease by means of direct sequencing. Part of the DRD1 gene exon of the blue fox was cloned; the length of the whole sequence was 864 bp. Four SNPs were detected and analyzed by the chi-square analysis; the results showed that the gene polymorphism of T206C in the DRD1 gene had a significant correlation with self-biting (P < 0.01). Therefore, marker-assistant selection on self-biting of blue foxes using these SNPs can be applied to select healthy individuals.
authors.affiliation: Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, State Key Laboratory for Molecular Biology of Special Economical Animals, Changchun, China.
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Liu
authors.affiliation: Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, State Key Laboratory for Molecular Biology of Special Economical Animals, Changchun, China.
authors.forename: E J
authors.initials: EJ
authors.lastname: Ren
authors.affiliation: Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, State Key Laboratory for Molecular Biology of Special Economical Animals, Changchun, China.
authors.forename: H X
authors.initials: HX
authors.lastname: Ba
authors.affiliation: Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, State Key Laboratory for Molecular Biology of Special Economical Animals, Changchun, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, State Key Laboratory for Molecular Biology of Special Economical Animals, Changchun, China.
authors.forename: H W
authors.initials: HW
authors.lastname: Zhu
authors.affiliation: Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, State Key Laboratory for Molecular Biology of Special Economical Animals, Changchun, China.
authors.forename: X M
authors.initials: XM
authors.lastname: Xing
authors.affiliation: Institute of Special Economic Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Jilin Provincial Key Laboratory for Molecular Biology of Special Economic Animals, State Key Laboratory for Molecular Biology of Special Economical Animals, Changchun, China yangfh@126.com.
authors.forename: F H
authors.initials: FH
authors.lastname: Yang
mesh_terms: D000818:Animals; D003001:Cloning, Molecular; D005589:Foxes / Q000235:genetics / Q000502:physiology*; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D020641:Polymorphism, Single Nucleotide; D017447:Receptors, Dopamine D1 / Q000235:genetics*; D017422:Sequence Analysis, DNA; D013239:Stereotyped Behavior
chemical_list: D017447:Receptors, Dopamine D1