title: Electrical nerve stimulation method for intraoperative localization of the inferior alveolar nerve within the mandible: a pilot study in rabbits.
abstract: The efficacy of the electrical nerve stimulation method for localizing the inferior alveolar nerve (IAN) within the mandibular bone was evaluated. Six New Zealand rabbits were used (both sides of the mandible). The IAN was stimulated through the mandibular bone and compound action potentials (CAPs) were recorded proximally from the main trunk of the nerve. Stimulation current pulse widths were set at 0.05, 0.1, 0.3, 0.5, and 1ms. The minimum current magnitude that generated a CAP with a criterion level (300mV peak-to-peak amplitude) was measured in the range of 0.05-5mA. Correlations between the distance of the IAN from the active electrode site and the minimum current magnitudes were studied for each pulse width. The correlation coefficients were 0.678, 0.807, 0.893, 0.851, and 0.890 for the pulse widths of 0.05, 0.1, 0.3, 0.5, and 1ms, respectively. The minimum current producing the criterion CAP response in the IAN was significantly (P<0.0001 for all pulse widths) and highly correlated with the distance between the stimulation site and the nerve. The results suggest that electrical nerve stimulation is a promising method that can be used for the localization of the IAN, especially during mandibular implant surgery.
authors.affiliation: Okmeydani Agiz ve Dis Sagligi Merkezi, Istanbul, Turkey; Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cukurova University, Adana, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Kuyumcu
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cukurova University, Adana, Turkey. Electronic address: ozgerdogan@yahoo.com.
authors.forename: Ö
authors.initials: Ö
authors.lastname: Erdogan
authors.affiliation: Institute of Biomedical Engineering, Boğaziçi University, Istanbul, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Güçlü
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D007432:Intraoperative Period; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000294:innervation* / Q000601:surgery*; D008340:Mandibular Nerve / Q000033:anatomy & histology*; D010027:Osteotomy; D010865:Pilot Projects; D011817:Rabbits; D011859:Radiography
keywords: bone; in vivo study; intraoperative neurophysiological monitoring; nerve location; trigeminal nerve