title: Does vaginal douching affect the type of candidal vulvovaginal infection?
abstract: The normal vaginal microbiota is a dynamic system that continually fluctuates under the environmental changes and different physiological conditions. Yeast infections of the vagina are caused by one of the species of fungus called Candida (C.). The study aimed to evaluate the types of mycobiota in women with vulvovaginal candidiasis (VVC) who were performing vaginal douching (VD) or not. Furthermore, it studied the antifungal sensitivity toward different fungi isolated from the vagina. In a cross-sectional study conducted in Assiut University Hospital, Egypt, women with VVC were interviewed regarding relevant history including the habit of VD. Vaginal swabs were obtained and processed by direct microscope and by culture on CHROMagar Candida and other differential media. The types of Candida in women with the habit of VD were compared with those not having this habit. We found that VD habit was practiced by 67.4% of women with VVC, and Candida albicans was the commonest (78.3%) type observed. There was no significant difference in the percentage of non-albicans types between women performing VD (23.6%) and those not reporting this habit (18.9%). Harboring non-albicans types were significantly increased in regular performers of VD compared with those who had this procedure only after sexual intercourse or after the end of menstruation (36.8%,12.5%, and 16.7%, respectively) (P = .048). Thus, vaginal douching does not influence the type of Candida infection involved in VVC. Frequent performance of VD increases the likelihood of having non-albicans types and the resistance to the common antifungal agents.
authors.affiliation: Assiut University, Obstetrics and gynecology, Assiut, Egypt.
authors.forename: Omar M
authors.initials: OM
authors.lastname: Shaaban
authors.affiliation: Assiut University, Obstetrics and gynecology, Assiut, Egypt bmr90@hotmail.com.
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Abbas
authors.affiliation: Assiut University, Botany Department, Assiut, Egypt.
authors.forename: Ahmad M
authors.initials: AM
authors.lastname: Moharram
authors.affiliation: Ibb University, Medical Microbiology, Ibb, Yemen.
authors.forename: Mohammed M
authors.initials: MM
authors.lastname: Farhan
authors.affiliation: Sohag University, Obstetrics and gynecology, Sohag, Egypt.
authors.forename: Ibrahim H
authors.initials: IH
authors.lastname: Hassanen
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology; D002175:Candida / Q000145:classification* / Q000187:drug effects / Q000302:isolation & purification*; D002181:Candidiasis, Vulvovaginal / Q000382:microbiology*; D003430:Cross-Sectional Studies; D004534:Egypt; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D014621:Vagina / Q000382:microbiology; D044364:Vaginal Douching / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D000935:Antifungal Agents
keywords: CHROMagar Candida; antifungal agents; vaginal douching; vulvovaginal candidiasis