title: Surgical Management of Giant Scalp Neurofibroma After Ultra-Selective Embolization of Nutrient Artery.
abstract: OBJECTIVE
  Neurofibroma, a common benign tumor in soft tissue, continues to grow, so it often appears to be giant. Surgical management of giant neurofibroma is a challenge due to the risk of excessive bleeding. Embolization of tumor's nutrient artery may reduce the blood loss in operation. This study introduces the surgical management of giant scalp neurofibroma with preoperative ultra-selective embolization of nutrient artery.
  
  
  METHODS
  From January 2006 to December 2013, 9 patients with giant scalp neurofibroma were enrolled into the study. Digital subtraction angiography (DSA) showed tumor's nutrient artery. Ultra-catheter was inserted into the nutrient artery and its branches as close as possible to the tumor. Then ultra-selective embolization was performed with gelatin sponge particles. Surgical removal of tumor was performed in 3 days after embolization. The wound was repaired by skin graft.
  
  
  RESULTS
  All of the 9 patients underwent successful DSA and ultra-selective embolization. Among them, occipital artery was embolized in 3 patients (left side in 1 patient and right side in 2 patients). Both occipital artery and superficial temporal artery were embolized in 6 patients (left side in 2 patients, right side in 3 patients, and both side in 1 patient). No complications, such as ectopic embolism, occurred in the patients. All of the tumors were resected completely without blood transfusion. The skin graft survived very well on the wounds.
  
  
  CONCLUSIONS
  Preoperative ultra-selective embolization of nutrient artery is a feasible, safe, and effective method to reduce the blood loss in operation and facilitate the surgical management of giant scalp neurofibroma.
authors.affiliation: Department of Plastic Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, China.
authors.forename: Si-Ming
authors.initials: SM
authors.lastname: Yuan
authors.forename: Yao
authors.initials: Y
authors.lastname: Guo
authors.forename: Lei
authors.initials: L
authors.lastname: Cui
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Xin-Bao
authors.initials: XB
authors.lastname: Hu
authors.forename: Ji-Hong
authors.initials: JH
authors.lastname: Zhou
authors.forename: Hui-Qing
authors.initials: HQ
authors.lastname: Jiang
authors.forename: Zhi-Jian
authors.initials: ZJ
authors.lastname: Hong
mesh_terms: D000293:Adolescent; D000328:Adult; D015901:Angiography, Digital Subtraction / Q000379:methods; D016063:Blood Loss, Surgical / Q000517:prevention & control; D002648:Child; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006258:Head and Neck Neoplasms / Q000098:blood supply / Q000601:surgery* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009455:Neurofibroma / Q000098:blood supply / Q000601:surgery* / Q000628:therapy; D009777:Occipital Bone / Q000098:blood supply; D012535:Scalp / Q000473:pathology / Q000601:surgery*; D012878:Skin Neoplasms / Q000098:blood supply / Q000601:surgery* / Q000628:therapy; D016038:Skin Transplantation / Q000379:methods; D013699:Temporal Arteries / Q000473:pathology; D055815:Young Adult