title: Canine olfaction and electronic nose detection of volatile organic compounds in the detection of cancer: a review.
abstract: Olfactory cancer detection shows promise as an affordable, precise, and noninvasive way to screen for cancer. This review focuses on two methods of olfactory cancer detection: first, the ability of canines to differentiate between cancerous and healthy individuals through the use of biological samples and second, electronic nose technology that uses chemical sensors to detect known biomarkers in exhaled breath. This review summarizes and critiques past research and outlines future directions to improve understanding of both canine olfaction and electronic nose technology.
authors.affiliation: a Department of Neuroscience , Skidmore College , Saratoga Springs , New York , USA.
authors.forename: Spencer W
authors.initials: SW
authors.lastname: Brooks
authors.affiliation: a Department of Neuroscience , Skidmore College , Saratoga Springs , New York , USA.
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Moore
authors.affiliation: a Department of Neuroscience , Skidmore College , Saratoga Springs , New York , USA.
authors.forename: Evan B
authors.initials: EB
authors.lastname: Marzouk
authors.affiliation: a Department of Neuroscience , Skidmore College , Saratoga Springs , New York , USA.
authors.forename: Frasier R
authors.initials: FR
authors.lastname: Glenn
authors.affiliation: a Department of Neuroscience , Skidmore College , Saratoga Springs , New York , USA.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Hallock
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D004285:Dogs; D062609:Electronic Nose; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D055549:Volatile Organic Compounds / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D055549:Volatile Organic Compounds
keywords: Biochemical markers; Cancer biomarkers; Detection/diagnosis