title: Mineralocorticoid receptor blockade-a novel approach to fight hyperkalaemia in chronic kidney disease.
abstract: Hyperkalaemia continues to be a major hazard of mineralocorticoid receptor blockade in an effort to retard the progression of chronic kidney disease (CKD). In cardiac patients on mineralocorticoid receptor blockade, RLY-5016 which captures K(+) in the colon has been effective in reducing the risk of hyperkalaemia. This compound might be useful in CKD as well.
authors.affiliation: Nierenzentrum , University of Heidelberg , Heidelberg , Germany.
authors.forename: E
authors.initials: E
authors.lastname: Ritz
authors.affiliation: Internal Medicine and Cardiovascular Disease , University of Michigan Medical School , Ann Arbor, MI , USA.
authors.forename: B
authors.initials: B
authors.lastname: Pitt
keywords: aldosterone blockade; chronic kidney disease; hyperkalaemia; potassium binder