title: Vitamin D Supplementation Does Not Improve the Severity or the Resolution of Ultraviolet B-Induced Acute Erythema.
abstract: BACKGROUND
  Whether vitamin D supplementation alleviates the severity of ultraviolet B (UVB)-induced erythema and/or facilitates its resolution remains undetermined.
  
  
  OBJECTIVE
  To study the effect of oral vitamin D on UVB-induced erythema and its resolution in fair-skinned subjects.
  
  
  METHODS
  UVB-induced erythema was quantified using a Chroma Meter® in 50 volunteers 48 h before and 10 days after the random administration of 200,000 IU vitamin D (n = 40) or placebo (n = 10). Resolution of erythema in both groups was assessed by chromametry 24, 48, and 72 h after vitamin D administration.
  
  
  RESULTS
  No statistical difference between erythema values before and after administration in the vitamin D-supplemented group (p = 0.44) or the placebo group (p = 0.34) was noted. No statistical difference was evident between both groups with respect to resolution of erythema (p = 0.30).
  
  
  CONCLUSIONS
  Oral vitamin D supplementation neither improves protection against UVB-induced erythema nor facilitates its resolution.
authors.affiliation: Department of Dermatology, CHU of Sart Tilman, University of Lix00E8;ge, Lix00E8;ge, Belgium.
authors.forename: Florence
authors.initials: F
authors.lastname: Libon
authors.forename: Laurence
authors.initials: L
authors.lastname: Seidel
authors.forename: Etienne
authors.initials: E
authors.lastname: Cavalier
authors.forename: Arjen F
authors.initials: AF
authors.lastname: Nikkels
mesh_terms: D000284:Administration, Oral; D019587:Dietary Supplements; D004890:Erythema / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D010865:Pilot Projects; D012621:Seasons; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014807:Vitamin D / Q000008:administration & dosage*; D014815:Vitamins / Q000008:administration & dosage; D055815:Young Adult
chemical_list: D014815:Vitamins; D014807:Vitamin D