title: Unstable spiral waves and local Euclidean symmetry in a model of cardiac tissue.
abstract: This paper investigates the properties of unstable single-spiral wave solutions arising in the Karma model of two-dimensional cardiac tissue. In particular, we discuss how such solutions can be computed numerically on domains of arbitrary shape and study how their stability, rotational frequency, and spatial drift depend on the size of the domain as well as the position of the spiral core with respect to the boundaries. We also discuss how the breaking of local Euclidean symmetry due to finite size effects as well as the spatial discretization of the model is reflected in the structure and dynamics of spiral waves. This analysis allows identification of a self-sustaining process responsible for maintaining the state of spiral chaos featuring multiple interacting spirals.
authors.affiliation: School of Physics, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Marcotte
authors.affiliation: School of Physics, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.
authors.forename: Roman O
authors.initials: RO
authors.lastname: Grigoriev
mesh_terms: D000818:Animals; D006801:Humans; D008955:Models, Cardiovascular; D009206:Myocardium; D017711:Nonlinear Dynamics