title: Pulmonary Tuberculosis in a Patient with Cystic Fibrosis.
abstract: BACKGROUND
  Mycobacterium tuberculosis (MTB) infection is rarely seen in cystic fibrosis (CF) patients.
  
  
  METHODS
  We report a 24-year-old CF patient with fever, cough, hemoptysis, and weight loss of 1week duration prior to admission. Past sputum cultures grew methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. The patient was treated with broad spectrum antibiotics based on previous culture data, but failed to improve. Chest radiograph and computed tomography (CT) chest revealed chronic collapse of the anterior subsegment of right upper lobe and multiple bilateral cavitary lesions which were worse compared to prior films. MTB was suspected and was confirmed by positive acid-fast bacilli (AFB) smears and cultures. After receiving first-line antituberculous drugs, the patient's condition markedly improved.
  
  
  CONCLUSIONS
  MTB is an infrequent finding, but considered a potential pathogen in CF patients, and may lead to serious pulmonary complications if there is a delay in diagnosis and treatment.
authors.affiliation: Department of Health, Arkansas, United States ; University of Arkansas for Medical Sciences, Arkansas, United States.
authors.forename: Naveen
authors.initials: N
authors.lastname: Patil
authors.affiliation: Department of Health, Arkansas, United States.
authors.forename: Asween
authors.initials: A
authors.lastname: Marco
authors.affiliation: University of Arkansas for Medical Sciences, Arkansas, United States.
authors.forename: Maria Theresa
authors.initials: MT
authors.lastname: Montales
authors.affiliation: University of Arkansas for Medical Sciences, Arkansas, United States.
authors.forename: Nutan
authors.initials: N
authors.lastname: Bhaskar
authors.affiliation: University of Arkansas for Medical Sciences, Arkansas, United States.
authors.forename: Penchala
authors.initials: P
authors.lastname: Mittadodla
authors.affiliation: Department of Health, Arkansas, United States ; University of Arkansas for Medical Sciences, Arkansas, United States.
authors.forename: Leonard N
authors.initials: LN
authors.lastname: Mukasa
keywords: AFB; Cystic fibrosis; GeneXpert MTB/RIF assay; Genotyping; MTB