title: Mimicking the niche: cytokines expand muscle stem cells.
abstract: Muscle stem cells (MuSCs) have long been considered to be potential therapeutic vehicles for diseases of muscle such as muscular dystrophies. A recent study published in Cell Research by Fu et al. reveals that recapitulating in vitro the in vivo microenvironment of MuSCs that occurs during muscle regeneration might be a major step towards translation.
authors.affiliation: 1] Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA [2] Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305, USA [3] Center for Tissue Regeneration, Repair, and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.
authors.forename: Marco
authors.initials: M
authors.lastname: Quarta
authors.affiliation: 1] Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA [2] Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305, USA [3] Center for Tissue Regeneration, Repair, and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA.
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Rando
mesh_terms: D000818:Animals; D006801:Humans; D007249:Inflammation / Q000378:metabolism*; D007371:Interferon-gamma / Q000378:metabolism*; D018793:Interleukin-13 / Q000378:metabolism*; D053582:Interleukin-1alpha / Q000378:metabolism*; D032496:Satellite Cells, Skeletal Muscle / Q000166:cytology* / Q000378:metabolism*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D018793:Interleukin-13; D053582:Interleukin-1alpha; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma