title: Mandibular lingual release versus mandibular lip-split approach for expanded resection of middle-late tongue cancer: A case-control study.
abstract: OBJECTIVE
  The mandibular lingual release (MLR) and mandibular lip-split (MS) approaches are the two common access approaches for resection of malignant tongue tumors. This case-control study aimed to evaluate the effectiveness and safety of these two approaches for the expanded resection of middle-late tongue cancer.
  
  
  METHODS
  A total of 56 matched patients with resectable middle-late squamous cell carcinoma of the tongue body were consecutively hospitalized for expanded resection using the MLR (n = 26) or MS approach (n = 30) between March 2004 and November 2012. Main outcome measures consisted of tumor exposure, surgical morbidity, maxillofacial motor-sensory return, and head/neck-specific quality of life.
  
  
  RESULTS
  The two approaches achieved similar en bloc R0 resection with similar tumor exposure. The MLR approach was associated with a significantly lower frequency of maxillofacial pain (P < 0.05) and no incidence of mandible nonunion. The MLR approach was also associated with a significantly better quality of life with respect to local pain, facial appearance, and mood.
  
  
  CONCLUSIONS
  Compared to the MS approach, the MLR approach was associated with significantly less surgical morbidity and a significantly better quality of life for middle-late tongue cancer patients undergoing expanded resection.
authors.affiliation: Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Jinzhong
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Yang
authors.affiliation: Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Su
authors.affiliation: Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Rudong
authors.initials: R
authors.lastname: Xing
authors.affiliation: Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China. Electronic address: hanf1989@hotmail.com.
authors.forename: Zhengxue
authors.initials: Z
authors.lastname: Han
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D016022:Case-Control Studies; D003679:Deglutition / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008046:Lip / Q000601:surgery*; D008297:Male; D008334:Mandible / Q000601:surgery*; D008409:Mastication / Q000502:physiology; D008875:Middle Aged; D009333:Neck / Q000601:surgery; D037981:Neck Dissection / Q000379:methods; D009334:Neck Muscles / Q000502:physiology / Q000601:surgery; D011183:Postoperative Complications; D011788:Quality of Life; D019651:Plastic Surgery Procedures / Q000379:methods; D012449:Safety; D012677:Sensation / Q000502:physiology; D013060:Speech / Q000502:physiology; D014062:Tongue Neoplasms / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Esthetic outcome; Mandible lip-split approach; Mandibular lingual release approach; Quality of life; Tongue cancer