title: Pirfenidone-induced photoleukomelanoderma in a patient with idiopathic pulmonary fibrosis.
abstract: This is believed to be the first report of pirfenidone-induced photoleukomelanoderma. We discuss the male predominance of photosensitivity induced by pirfenidone. Both ultraviolet (UV)-A and UV-B seemed to be included within the action spectrum of this disorder. Although pirfenidone is a key drug for the treatment of idiopathic pulmonary fibrosis, clinicians should be aware of the high prevalence of photosensitivity and perform sufficient patient education for comprehensive photoprotection before prescription.
authors.affiliation: Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Aoi
authors.initials: A
authors.lastname: Tsuruta
authors.affiliation: Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Washio
authors.affiliation: Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Fukunaga
authors.affiliation: Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Chikako
authors.initials: C
authors.lastname: Nishigori
mesh_terms: D000368:Aged; D017484:Dermatitis, Phototoxic / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced* / Q000473:pathology / Q000517:prevention & control; D054990:Idiopathic Pulmonary Fibrosis / Q000188:drug therapy*; D008297:Male; D011728:Pyridones / Q000009:adverse effects*
chemical_list: D011728:Pyridones; C093844:pirfenidone
keywords: drug eruption; idiopathic pulmonary fibrosis; photoleukomelanoderma; photosensitivity; pirfenidone