title: A Simple Numerical Body Surface Mapping Parameter Signifies Successful Percutaneous Coronary Artery Intervention.
abstract: BACKGROUND
  In coronary artery disease (CAD), body surface potential mapping (BSPM) may reveal minor electrical potential changes appearing in the depolarization phase even if pathological changes are absent on the conventional 12-lead ECG. We hypothesized that a simple BSPM parameter, Max/Min signifies successful percutaneous coronary intervention (PCI).
  
  
  METHODS
  Ninety-two adult Caucasian patients with stable CAD and positive exercise test underwent coronary angiography. Seventy patients (age, 59 ± 8; 46 males) were revascularized by PCI (left anterior descending [LAD] in 38, right [RCA] in 17 and left circumflex [LCX] coronary artery in 15). Control groups contained 22 patients (age, 60 ± 8; 14 males) without intervention and 35 healthy subjects (age, 58 ± 2; 15 males). Left ventricular ejection fraction (LVEF, transthoracic echocardiography) and Max/Min BSPM parameter (63-lead Montreal system) were evaluated before and 4-40 days following coronary angiography. Max/Min was defined by the ratio of the highest maximum to the deepest minimum potential of all leads recorded by BSPM.
  
  
  RESULTS
  Before PCI, Max/Min value of patients with LAD lesion (0.83 [0.74; 0.93]) was significantly lower while that with RCA lesion (1.63 [1.35; 1.99]) was significantly higher than that of healthy group (1.01 [0.970; 1.13]) (P < 0.05) and LVEF was significantly lower in LAD lesion (46.50% [43.00; 51.00]) than in the healthy group (55.00% [50.00; 58.75]) (P < 0.01). Max/Min value significantly increased from 0.83 [0.74; 0.93] to 0.92 [0.82; 0.99] (P < 0.01) following LAD PCI while significantly decreased from 1.63 [1.35; 1.98] to 1.35 [1.21; 1.43] (P < 0.01) post-RCA PCI. It did not vary significantly, however, either following LCX PCI or without intervention. LVEF significantly increased (from 46.50% [43.00; 51.00] to 49.00% [46.00; 51.00]) only after LAD PCI.
  
  
  CONCLUSIONS
  Max/Min parameter is suitable to follow patients after LAD and RCA PCI.
authors.affiliation: Metabolic Center, Szent Imre University Teaching Hospital, Budapest, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Simonyi
authors.affiliation: Flor Ferenc Hospital of Pest County, Kistarcsa, Hungary.
authors.forename: Róbert
authors.initials: R
authors.lastname: Kirschner
authors.affiliation: Spital Waldshut, Waldshut-Tiengen, Germany.
authors.forename: Endre
authors.initials: E
authors.lastname: Szűcs
authors.affiliation: Department of Cardiology, Medical Center, Hungarian Defence Forces, Budapest, Hungary.
authors.forename: István
authors.initials: I
authors.lastname: Préda
authors.affiliation: Department of Cardiology, Medical Center, Hungarian Defence Forces, Budapest, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Duray
authors.affiliation: KRKA Hungary Ltd, Budapest, Hungary.
authors.forename: Nóra
authors.initials: N
authors.lastname: Medvegy
authors.affiliation: Peterfy Street Municipal Hospital and Trauma Centre, Budapest, Hungary.
authors.forename: Bálint
authors.initials: B
authors.lastname: Horvath
authors.affiliation: Flor Ferenc Hospital of Pest County, Kistarcsa, Hungary.
authors.forename: Mihály
authors.initials: M
authors.lastname: Medvegy
mesh_terms: D018780:Body Surface Potential Mapping / Q000379:methods* / Q000706:statistics & numerical data*; D003324:Coronary Artery Disease / Q000601:surgery*; D004562:Electrocardiography / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000379:methods* / Q000706:statistics & numerical data*
keywords: catheterization; electrophysiology; hibernating myocardium; ischemic heart disease; mapping