title: Eosinophilia in patients infected with human immunodeficiency virus.
abstract: Eosinophilia is not uncommonly encountered in patients infected with human immunodeficiency virus (HIV), particularly at initiation of care or among those with advanced disease. The clinical manifestation most commonly associated with eosinophilia in this patient population is skin rash. Management of these patients is challenging due to a paucity of data evaluating diagnostic testing and therapeutic strategies. Patients born in or with significant travel to parasite-endemic countries are more likely to have tissue-invasive helminthes, such as Strongyloides or Schistosoma. Patients without such risk factors are unlikely to have parasitic infections and frequently will have self-resolution of eosinophilia. When a detailed history, physical exam, and diagnostic work-up are unrevealing, we sometimes consider empirical therapy with ivermectin. Praziquantel may also be considered for those at risk for schistosomiasis.
authors.affiliation: Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, BCM 286, Houston, TX, 77030, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Chou
authors.forename: Jose A
authors.initials: JA
authors.lastname: Serpa
mesh_terms: D000977:Antiparasitic Agents / Q000627:therapeutic use; D004802:Eosinophilia / Q000209:etiology / Q000503:physiopathology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D009181:Mycoses / Q000150:complications*; D010272:Parasitic Diseases / Q000150:complications*; D011379:Prognosis
chemical_list: D000977:Antiparasitic Agents