title: Screening of a Marine Algal Extract for Antifungal Activities.
abstract: Over the past few years algal extracts have become increasingly interesting to the scientific community due to their promising biological properties. Phlorotannin extracts are particularly attractive partly due to their reported antifungal activity against several yeast and dermatophyte strains.The micromethod used for the evaluation of the minimum inhibitory concentration (MIC) and the minimum lethal concentration (MLC) represents an effective and solvent-saving procedure to evaluate the antifungal activity of algae extracts. Here we describe the micromethod for determining the MIC and the MLC of algal extracts by using the example of a purified phlorotannin extract of brown algae.
authors.affiliation: REQUIMTE/Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge de Viterbo Ferreira 228, 4050-313, Porto, Portugal.
authors.forename: Graciliana
authors.initials: G
authors.lastname: Lopes
authors.forename: Paula B
authors.initials: PB
authors.lastname: Andrade
authors.forename: Patrícia
authors.initials: P
authors.lastname: Valentão
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D004867:Equipment Design; D005658:Fungi / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000295:instrumentation / Q000379:methods*; D009181:Mycoses / Q000188:drug therapy; D000459:Phaeophyceae / Q000737:chemistry*; D013634:Tannins / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D013634:Tannins