title: Calcium-to-creatinine ratio in pregnancy-induced hypertension.
abstract: OBJECTIVE
  Hypocalciuria has been correlated with preeclampsia. This study compared the calcium-to-creatinine ratio among the groups, and the correlation with the 24-h measurement of this ratio and a diagnosis of preeclampsia.
  
  
  METHODS
  Case-control study including mild and severe preeclampsia, chronic hypertension and normal pregnancy.
  
  
  METHODS
  The calcium-to-creatinine ratio differentiates severe preeclampsia from mild preeclampsia, chronic hypertension and normal pregnancy.
  
  
  RESULTS
  There were statistically significant differences between the groups when comparing severe preeclampsia and chronic hypertension, severe preeclampsia and normal pregnancy, and mild and severe preeclampsia (p<0.0001). The Spearman index between the calcium-to-creatinine ratio and 24-h calciuria was 0.65 (high correlation).
  
  
  CONCLUSIONS
  The calcium-to-creatinine ratio can reliably estimate 24-h calciuria, differentiating severe preeclampsia from mild preeclampsia, chronic hypertension and normal pregnancy.
authors.affiliation: Post-Graduate Program in Medicine: Medical Sciences, Brazil. Electronic address: gasnier.rose@gmail.com.
authors.forename: Rose
authors.initials: R
authors.lastname: Gasnier
authors.affiliation: Service of Obstetrics and Gynecology, Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: Edimárlei Gonsales
authors.initials: EG
authors.lastname: Valério
authors.affiliation: Service of Obstetrics and Gynecology, Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: Janete
authors.initials: J
authors.lastname: Vettorazzi
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Federal University of Rio Grande do Sul, Brazil; Service of Obstetrics and Gynecology, Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: Sérgio Hofmeister
authors.initials: SH
authors.lastname: Martins-Costa
authors.affiliation: Post-Graduate Program in Medicine: Medical Sciences, Brazil; Service of Nephrology, Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: Elvino Guardão
authors.initials: EG
authors.lastname: Barros
authors.affiliation: Post-Graduate Program in Medicine: Medical Sciences, Brazil; Department of Obstetrics and Gynecology, School of Medicine, Federal University of Rio Grande do Sul, Brazil; Service of Obstetrics and Gynecology, Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: José Geraldo Lopes
authors.initials: JG
authors.lastname: Ramos
keywords: Calcium-to-creatinine ratio; High-risk pregnancy; Hypocalciuria; Preeclampsia; Pregnancy hypertension