title: Medication adherence in type 2 diabetes patients: study of patients in Alimosho General Hospital, Igando, Lagos, Nigeria.
abstract: BACKGROUND
  Poor adherence is an obstacle in therapeutic control of diabetes. Despite the advances in the treatment of diabetes mellitus over the years, diabetes places an immense burden on the individuals living with the condition, their families and the overall health care system.
  
  
  OBJECTIVE
  Evaluation of the impact of medication adherence on the clinical outcomes of type 2 diabetes patients at Alimosho general hospital, Igando Lagos state.
  
  
  METHODS
  The medication adherence study was both descriptive (retrospective) and prospective. The retrospective study assessed the prevalence of medication non-adherence leading to poor glycemic control. This involved the review of case notes of one-hundred and fifty two randomly selected patients. Prospective study was done by counselling and educating the patients on medication adherence and assessing their medication adherence and the impact of medication adherence on glycemic control.
  
  
  RESULTS
  The proportions of females/males with type 2 DM was found to be 69% and 31% respectively. 51.32% of these patients viewed their medications to be unaffordable. 56.6% of the patient population were 61 years and above in age. There was a significant relationship between patient age, gender and adherence to medication. There was however no significant P ≥ 0.05 association between educational level and adherence. Health education and counselling resulted in adherence rate and clinical parameters improvements.
  
  
  CONCLUSIONS
  Non-adherence is a major factor that could lead to morbidity and mortality in diabetic patients. The overall improvement in adherence rate of 86.8% was observed with a decline in non- adherence rate after interventions.
authors.affiliation: Department of Pharmacology, Therapeutics & Toxicology, College of Medicine, PMB 12003, Idi Araba, University of Lagos, Lagos-Nigeria.
authors.forename: Olufunsho
authors.initials: O
authors.lastname: Awodele
authors.affiliation: Department of Pharmacy, Alimosho General Hospital, Igando, Lagos-Nigeria.
authors.forename: Jemeela A
authors.initials: JA
authors.lastname: Osuolale
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000187:drug effects*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D019538:Health Care Surveys; D007722:Health Knowledge, Attitudes, Practice; D006769:Hospitals, General; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D055118:Medication Adherence / Q000523:psychology; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D011446:Prospective Studies; D012189:Retrospective Studies; D016903:Drug Monitoring
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: Diabetes type 2; adherence; glycemic level; health education and counselling