title: Bioactive Functions of Milk Proteins: a Comparative Genomics Approach.
abstract: The composition of milk includes factors required to provide appropriate nutrition for the growth of the neonate. However, it is now clear that milk has many functions and comprises bioactive molecules that play a central role in regulating developmental processes in the young while providing a protective function for both the suckled young and the mammary gland during the lactation cycle. Identifying these bioactives and their physiological function in eutherians can be difficult and requires extensive screening of milk components that may function to improve well-being and options for prevention and treatment of disease. New animal models with unique reproductive strategies are now becoming increasingly relevant to search for these factors.
authors.affiliation: Institute for Frontier Materials, Deakin University, Geelong, 3216, Australia, Julie.Sharp@deakin.edu.au.
authors.forename: Julie A
authors.initials: JA
authors.lastname: Sharp
authors.forename: Vengama
authors.initials: V
authors.lastname: Modepalli
authors.forename: Ashwanth Kumar
authors.initials: AK
authors.lastname: Enjapoori
authors.forename: Swathi
authors.initials: S
authors.lastname: Bisana
authors.forename: Helen E
authors.initials: HE
authors.lastname: Abud
authors.forename: Christophe
authors.initials: C
authors.lastname: Lefevre
authors.forename: Kevin R
authors.initials: KR
authors.lastname: Nicholas
mesh_terms: D000818:Animals; D005075:Biological Evolution; D004064:Digestive System / Q000254:growth & development; D005260:Female; D023281:Genomics; D006801:Humans; D007774:Lactation / Q000502:physiology*; D008168:Lung / Q000254:growth & development; D008322:Mammals / Q000502:physiology*; D008394:Marsupialia / Q000502:physiology; D035683:MicroRNAs / Q000378:metabolism*; D008892:Milk / Q000737:chemistry / Q000276:immunology / Q000378:metabolism*; D008894:Milk Proteins; D008895:Milk, Human / Q000737:chemistry / Q000276:immunology / Q000378:metabolism*; D023421:Models, Animal; D009007:Monotremata / Q000502:physiology; D010455:Peptides / Q000378:metabolism
chemical_list: D035683:MicroRNAs; D008894:Milk Proteins; D010455:Peptides