title: Ultrasound findings of mild neonatal periventricular-intraventricular hemorrhage after different treatments.
abstract: OBJECTIVE
  To investigate the ultrasound findings of mild neonatal periventricular-intraventricular hemorrhage (PIVH) after different treatments, and to evaluate the neurological outcomes of mild PIVH with Gesell Development Diagnosis Scale (GDDS).
  
  
  METHODS
  A total of 194 newborns with grade I-II PIVH were recruited, and findings of cranial ultrasound examination before and 1 month after birth were included for analysis. The echo intensity and size of the lesions were recorded.
  
  
  RESULTS
  There was no significant difference in the echo intensity among three groups of grade I PIVH patients (P>0.05). There was significant difference in the echo intensity among three groups of grade II PIVH patients, and the ganglioside had the best therapeutic efficacy (P<0.05). No significant difference was observed in the area change among three groups of grade I PIVH patients (P>0.05). However, significant difference was observed in the area change among three groups of grade II PIVH patients, and ganglioside had a better efficacy than cerebrolysin and control agent (P<0.05), but there was no significant difference between cerebrolysin and control groups (P>0.05). GDDS evaluation showed no significant difference among three groups (P>0.05), and all the patients recovered completely.
  
  
  CONCLUSIONS
  The efficacy of different treatments for mild PIVH can be reflected in the ultrasound findings. Mild PIVH children generally have a good neurological prognosis.
authors.affiliation: Department of Diagnostic Ultrasound, First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.
authors.forename: Sida
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Diagnostic Ultrasound, First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.
authors.forename: Chunyan
authors.initials: C
authors.lastname: Liao
authors.affiliation: Department of Diagnostic Ultrasound, First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.
authors.forename: Shuyuan
authors.initials: S
authors.lastname: Liang
authors.affiliation: Department of Neonatology, First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.
authors.forename: Danni
authors.initials: D
authors.lastname: Zhong
authors.affiliation: Department of Diagnostic Ultrasound, First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Diagnostic Ultrasound, First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China.
authors.forename: Zhixian
authors.initials: Z
authors.lastname: Li
keywords: Gesell Development Diagnosis Scale; Periventricular-intraventricular hemorrhage; neonatal; ultrasound