title: Organocatalytic asymmetric reaction of indol-2-yl carbinols with enamides: synthesis of chiral 2-indole-substituted 1,1-diarylalkanes.
abstract: The chiral phosphoramide-catalyzed asymmetric reaction of indol-2-yl carbinols with enamides is presented. The method provided an efficient and novel way for the synthesis of chiral 2-indole-substituted 1,1-diarylalkane derivatives.
authors.affiliation: Key Lab of Synthetic Rubber, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, China. fshan@ciac.ac.cn.
authors.forename: Chao-You
authors.initials: CY
authors.lastname: Liu
authors.forename: Fu-She
authors.initials: FS
authors.lastname: Han
mesh_terms: D000473:Alkanes / Q000138:chemical synthesis* / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D063088:Phosphoramides / Q000737:chemistry*
chemical_list: D000473:Alkanes; D000577:Amides; D007211:Indoles; D063088:Phosphoramides; C005438:phosphoramide