title: Intrapleural cisplatin for management of malignant pleural effusion in a patient with plasma cell leucaemia.
abstract: Plasma cell leucaemia (PCL) is a rare aggressive form of multiple myeloma. It occasionally involves the pleura, causing malignant pleural effusion (MPE). MPE presents a management dilemma for physicians, given the different treatment options available with varying efficacy and side effects. We report a case of a 64-year-old man with MPE due to PCL, successfully managed with intrapleural cisplatin and a tunnelled pleural catheter. We believe this to be the first report of management of PCL-associated MPE with intrapleural cisplatin.
authors.affiliation: Cooper University Hospital, Camden, New Jersey, USA.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Jagpal
authors.initials: J
authors.lastname: Klair
authors.affiliation: University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Setu
authors.initials: S
authors.lastname: Patolia
authors.affiliation: Department of Pulmonary and Critical Care Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: Nikhil K
authors.initials: NK
authors.lastname: Meena
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D057785:Catheters; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology*; D010994:Pleura / Q000473:pathology*; D016066:Pleural Effusion, Malignant / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin