title: Sleep neurobiology and critical care illness.
abstract: The intensive care unit (ICU) environment is not propitious for restoring sleep and many studies have reported that critically ill patients have severe sleep disruptions. However, sleep alterations in critically ill patients are specific and differ significantly from those in ambulatory patients. Polysomnographic patterns of normal sleep are frequently lacking in critically ill patients and the neurobiology of sleep is important to consider regarding alternative methods to quantify sleep in the ICU. This article discusses elements of sleep neurobiology affecting the specificity of sleep patterns and sleep alterations in patients admitted to the ICU.
authors.affiliation: CHU de Poitiers, Department of Clinical Neurophysiology, Hôpital Jean Bernard, 2 rue de la Milétrie, Poitiers 86000, France; Univ Poitiers, University of Medicine and Pharmacy, 6 rue de la Milétrie, Poitiers 86000, France; INSERM, CIC 1402, Equipe Alive, CHU de Poitiers, Cours Est J. Bernard, Poitiers 86000, France. Electronic address: xavier.drouot@chu-poitiers.fr.
authors.forename: Xavier
authors.initials: X
authors.lastname: Drouot
authors.affiliation: CHU de Poitiers, Department of Clinical Neurophysiology, Hôpital Jean Bernard, 2 rue de la Milétrie, Poitiers 86000, France; Univ Poitiers, University of Medicine and Pharmacy, 6 rue de la Milétrie, Poitiers 86000, France; INSERM, CIC 1402, Equipe Alive, CHU de Poitiers, Cours Est J. Bernard, Poitiers 86000, France.
authors.forename: Solene
authors.initials: S
authors.lastname: Quentin
mesh_terms: D002940:Circadian Rhythm / Q000502:physiology; D016638:Critical Illness; D006801:Humans; D007362:Intensive Care Units; D012890:Sleep / Q000502:physiology*; D012892:Sleep Deprivation / Q000209:etiology; D012894:Sleep Stages / Q000502:physiology; D012893:Sleep Wake Disorders / Q000209:etiology* / Q000503:physiopathology
keywords: Circadian rhythms; Neurobiology; Sleep EEG pattern; Sleep alterations; Sleep organization