title: Optical imaging probes for biomolecules: an introductory perspective.
abstract: An overview of optical biomolecular imaging is provided. Following a brief history of the development of probes and technologies in this area, general approaches which use biomolecular imaging in current commercial systems are discussed. A brief summary of research challenges in this area - in terms of both the chemistry and technique development - is introduced. Finally, areas rich for possible future development are suggested.
authors.affiliation: Department of Chemistry, University of Sheffield, Sheffield, UK. james.thomas@sheffield.ac.uk.
authors.forename: Jim A
authors.initials: JA
authors.lastname: Thomas
mesh_terms: D001706:Biopsy; D005456:Fluorescent Dyes; D006367:HeLa Cells; D006801:Humans; D008168:Lung / Q000473:pathology; D036641:Microscopy, Fluorescence, Multiphoton; D061848:Optical Imaging
chemical_list: D005456:Fluorescent Dyes