title: Adolescent impatience decreases with increased frontostriatal connectivity.
abstract: Adolescence is a developmental period associated with an increase in impulsivity. Impulsivity is a multidimensional construct, and in this study we focus on one of the underlying components: impatience. Impatience can result from (i) disregard of future outcomes and/or (ii) oversensitivity to immediate rewards, but it is not known which of these evaluative processes underlie developmental changes. To distinguish between these two causes, we investigated developmental changes in the structural and functional connectivity of different frontostriatal tracts. We report that adolescents were more impatient on an intertemporal choice task and reported less future orientation, but not more present hedonism, than young adults. Developmental increases in structural connectivity strength in the right dorsolateral prefrontal tract were related to increased negative functional coupling with the striatum and an age-related decrease in discount rates. Our results suggest that mainly increased control, and the integration of future-oriented thought, drives the reduction in impatience across adolescence.
authors.affiliation: Center for Adaptive Rationality, Max Planck Institute for Human Development, 14197 Berlin, Germany; Department of Psychology, Stanford University, Stanford, CA 94305; vandenbos@mpib-berlin.mpg.de.
authors.forename: Wouter
authors.initials: W
authors.lastname: van den Bos
authors.affiliation: Department of Psychology, Stanford University, Stanford, CA 94305;
authors.forename: Christian A
authors.initials: CA
authors.lastname: Rodriguez
authors.affiliation: MIND Institute, University of California, Davis, School of Medicine, Sacramento, CA 95817; Department of Psychiatry and Behavioral Sciences, University of California, Davis, School of Medicine, Sacramento, CA 95817.
authors.forename: Julie B
authors.initials: JB
authors.lastname: Schweitzer
authors.affiliation: Department of Psychology, Stanford University, Stanford, CA 94305;
authors.forename: Samuel M
authors.initials: SM
authors.lastname: McClure
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002755:Choice Behavior; D056324:Diffusion Tensor Imaging; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000502:physiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D017072:Neostriatum / Q000033:anatomy & histology / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology*; D012201:Reward; D013647:Task Performance and Analysis; D055815:Young Adult
keywords: DTI; adolescence; connectivity; delay discounting; impatience