title: Endovascular Repair of a False Aneurysm Developing from IgG4-Related Periaortitis during Corticosteroid Therapy.
abstract: Immunoglobulin G4 (IgG4)-related disease is a systemic autoimmune disease that can affect various organs. Corticosteroid therapy is generally an effective treatment; however, IgG4-related aortic lesions pose a risk of aortic rupture related to corticosteroid use. Here, we report a case of IgG4-related periaortitis complicated with a false aneurysm during corticosteroid therapy. Although endovascular repair was successfully performed, autoimmune pancreatitis and sclerosing cholangitis emerged after surgery. The multiple lesions associated with IgG4-related disease were resolved through continuous corticosteroid therapy. Our case suggests that both appropriate surgical intervention and continuous corticosteroid therapy are essential for the treatment of IgG4-related periaortitis.
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Medical Center Hospital, Tsukuba, Japan. Electronic address: ai-cvs@sd6.so-net.ne.jp.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Ikeda
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Medical Center Hospital, Tsukuba, Japan.
authors.forename: Kisato
authors.initials: K
authors.lastname: Mitomi
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Medical Center Hospital, Tsukuba, Japan.
authors.forename: Taisuke
authors.initials: T
authors.lastname: Konishi
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Medical Center Hospital, Tsukuba, Japan.
authors.forename: Kanji
authors.initials: K
authors.lastname: Matsuzaki
authors.affiliation: Department of Cardiovascular Surgery, Tsukuba Medical Center Hospital, Tsukuba, Japan.
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Jikuya
authors.affiliation: Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Hiramatsu
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D017541:Aneurysm, False / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D001014:Aortic Aneurysm / Q000175:diagnosis / Q000276:immunology / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001327:Autoimmune Diseases / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D019917:Blood Vessel Prosthesis Implantation; D015209:Cholangitis, Sclerosing / Q000276:immunology; D057510:Endovascular Procedures; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D010195:Pancreatitis / Q000276:immunology; D012185:Retroperitoneal Fibrosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007074:Immunoglobulin G