title: Antibodies: At The Nexus of Antigens and Cancer Vaccines.
abstract: This review describes the development of monoclonal antibodies and the inception of their use in cancer therapy, their impact on defining cancer biomarkers, and their structural utility in new cancer vaccine development.
authors.affiliation: Malvern, Pennsylvania.
authors.forename: Zenon
authors.initials: Z
authors.lastname: Steplewski
authors.affiliation: Cancer Diagnosis Program, National Cancer Institute, National Institutes of Health, Rockville, Maryland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Thurin
authors.affiliation: Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock.
authors.forename: Thomas
authors.initials: T
authors.lastname: Kieber-Emmons
mesh_terms: D000818:Animals; D000906:Antibodies / Q000276:immunology / Q000627:therapeutic use; D000911:Antibodies, Monoclonal; D015295:Antigens, Tumor-Associated, Carbohydrate; D001709:Biotechnology; D019496:Cancer Vaccines; D006801:Humans; D051379:Mice; D009369:Neoplasms / Q000188:drug therapy / Q000276:immunology; D015398:Signal Transduction
chemical_list: D000906:Antibodies; D000911:Antibodies, Monoclonal; D015295:Antigens, Tumor-Associated, Carbohydrate; D019496:Cancer Vaccines
keywords: Monoclonal antibodies; anti-idiotypes; biotechnology; cancer therapeutics; cancer vaccines; carbohydrate mimetic peptides; mimicry; team science