title: Ag nanocluster-based label-free catalytic and molecular beacons for amplified biosensing.
abstract: By employing DNAzyme as a recognition group and amplifier, and DNA-stabilized silver nanoclusters (DNA/AgNCs) as signal reporters, we reported for the first time a label-free catalytic and molecular beacon as an amplified biosensing platform for highly selective detection of cofactors such as Pb(2+) and L-histidine.
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn.
authors.forename: Liang
authors.initials: L
authors.lastname: Gong
authors.forename: Hailan
authors.initials: H
authors.lastname: Kuai
authors.forename: Songlei
authors.initials: S
authors.lastname: Ren
authors.forename: Xu-Hua
authors.initials: XH
authors.lastname: Zhao
authors.forename: Shuang-Yan
authors.initials: SY
authors.lastname: Huan
authors.forename: Xiao-Bing
authors.initials: XB
authors.lastname: Zhang
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D002413:Cations, Divalent / Q000032:analysis / Q000378:metabolism; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D021881:DNA, Catalytic / Q000378:metabolism*; D006639:Histidine / Q000032:analysis* / Q000378:metabolism; D007854:Lead / Q000032:analysis* / Q000378:metabolism; D057230:Limit of Detection; D049329:Nanostructures / Q000737:chemistry*; D045483:Rivers / Q000737:chemistry; D012834:Silver / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods
chemical_list: D002413:Cations, Divalent; D021881:DNA, Catalytic; D007854:Lead; D012834:Silver; D006639:Histidine; D004247:DNA