title: Accelerating the Translation of Nanomaterials in Biomedicine.
abstract: Due to their size and tailorable physicochemical properties, nanomaterials are an emerging class of structures utilized in biomedical applications. There are now many prominent examples of nanomaterials being used to improve human health, in areas ranging from imaging and diagnostics to therapeutics and regenerative medicine. An overview of these examples reveals several common areas of synergy and future challenges. This Nano Focus discusses the current status and future potential of promising nanomaterials and their translation from the laboratory to the clinic, by highlighting a handful of successful examples.
authors.affiliation: †Center for Bioengineering, Department of Chemical Engineering, University of California, Santa Barbara, California 93106, United States.
authors.forename: Samir
authors.initials: S
authors.lastname: Mitragotri
authors.affiliation: ‡Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Anderson
authors.affiliation: §National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland 20892, United States.
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Chen
authors.affiliation: ∥Cancer Science Institute of Singapore, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077.
authors.forename: Edward K
authors.initials: EK
authors.lastname: Chow
authors.affiliation: ⊥Division of Oral Biology and Medicine, UCLA School of Dentistry, Los Angeles, California 90095, United States.
authors.forename: Dean
authors.initials: D
authors.lastname: Ho
authors.affiliation: #Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Kabanov
authors.affiliation: ¶Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States.
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Karp
authors.affiliation: □Departments of Materials Engineering and Bioengineering, University of Tokyo, Tokyo 113-8654, Japan.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Kataoka
authors.affiliation: ■Department of Chemistry and International Institute for Nanotechnology, Northwestern University, Evanston, Illinois 60208, United States.
authors.forename: Chad A
authors.initials: CA
authors.lastname: Mirkin
authors.affiliation: ■Department of Chemistry and International Institute for Nanotechnology, Northwestern University, Evanston, Illinois 60208, United States.
authors.forename: Sarah Hurst
authors.initials: SH
authors.lastname: Petrosko
authors.forename: Jinjun
authors.initials: J
authors.lastname: Shi
authors.affiliation: ●Department of Materials, Department of Bioengineering, Institute for Biomedical Engineering, Imperial College London, London SW7 2AZ, U.K.
authors.forename: Molly M
authors.initials: MM
authors.lastname: Stevens
authors.affiliation: △Department of Chemistry, Brown University, Providence, Rhode Island 02912, United States.
authors.forename: Shouheng
authors.initials: S
authors.lastname: Sun
authors.forename: Sweehin
authors.initials: S
authors.lastname: Teoh
authors.forename: Subbu S
authors.initials: SS
authors.lastname: Venkatraman
authors.affiliation: ▼The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30322, United States.
authors.forename: Younan
authors.initials: Y
authors.lastname: Xia
authors.affiliation: ⬡Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Shutao
authors.initials: S
authors.lastname: Wang
authors.affiliation: ⬢Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695, United States.|††Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.|‡‡Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27695, United States.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Gu
authors.forename: Chenjie
authors.initials: C
authors.lastname: Xu
mesh_terms: D050997:Nanomedicine / Q000379:methods* / Q000639:trends; D057170:Translational Research, Biomedical