title: The Study of Effect for General Movements Assessment in the Diagnosis of Neurological Development Disorders: A Meta-Analysis.
abstract: OBJECTIVE
  To discuss the value of general movements assessment in predicting the neurological disorders.
  
  
  METHODS
  Using PubMed as the search engine, we searched to identify relevant studies in English and Chinese language published up to November 2014 and 19 studies were selected. Standard methods in meta-analyses were used to provide diagnostic accuracy by Meta-DiSc 1.4.
  
  
  RESULTS
  For non-cerebral palsy (non-CP) as outcome for writhing period, the results suggested a good sensitivity and a specificity of 0.74, the Q-value was 0.80. The area under the curve (AUC) was 0.87. For non-CP as outcome for fidgety period, the results suggested both high level for sensitivity and specificity. And the Q-value was 0.914, the AUC was 0.9664. For CP as outcome for writhing and fidgety periods, good sensitivity and specificity were found in the analysis, and the Q-value was 0.9034 while the AUC was 0.9592.
  
  
  CONCLUSIONS
  General movements assessment is a good predictor for diagnosing neurological disorders.
authors.affiliation: The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, China.
authors.forename: Kegong
authors.initials: K
authors.lastname: Xie
authors.affiliation: The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zheng
authors.affiliation: The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, China.
authors.forename: Huawei
authors.initials: H
authors.lastname: Li
authors.affiliation: The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, China.
authors.forename: Chi
authors.initials: C
authors.lastname: Zhang
authors.affiliation: The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Li
authors.affiliation: The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Jin
authors.affiliation: The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan Province, China xiekegong@126.com.
authors.forename: Bingxiang
authors.initials: B
authors.lastname: Ma
mesh_terms: D002648:Child; D002657:Child Development / Q000502:physiology*; D003937:Diagnosis, Differential; D006801:Humans; D009068:Movement / Q000502:physiology*; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000503:physiopathology*
keywords: cerebral palsy; general movements; meta-analysis; neurodevelopment