title: Feasibility and Acceptability of an Alcohol Addiction Therapy Integrated in a Transplant Center for Patients Awaiting Liver Transplantation.
abstract: OBJECTIVE
  To evaluate the feasibility and acceptability of an addiction program within the setting of liver transplantation, with classification of behavior change techniques used to reduce excessive drinking.
  
  
  METHODS
  Patients with alcohol-related liver disease (N = 100) participated in a manualized addiction group therapy over 12 sessions, pre-transplantation. Relapses were identified by measurement of urinary ethyl glucuronide (EtG).
  
  
  RESULTS
  Two groups were identified according to the frequency of participation: completers (n = 42) vs. drop-outs (n = 58). A total of 16.5% of the samples of completers in comparison to 30.5% of the samples of drop-outs tested positive for EtG (P < 0.001).
  
  
  CONCLUSIONS
  The results suggest that implementation of an addiction therapy program during the waiting time might help to limit the frequency of drinking. These patients appeared often to under-report their alcohol consumption; including a biomarker such as urinary EtG in such settings is recommended.
authors.affiliation: Department of Psychosomatic and Psychotherapeutic Medicine, University Hospital of Erlangen, Erlangen, Germany yesim.erim@uk-erlangen.de.
authors.forename: Yesim
authors.initials: Y
authors.lastname: Erim
authors.affiliation: MVZ Labor Dessau GmbH, Dessau-Roßlau, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Böttcher
authors.affiliation: Department of Psychosomatic and Psychotherapeutic Medicine, University Hospital of Erlangen, Erlangen, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Schieber
authors.affiliation: Department of Psychosomatic and Psychotherapeutic Medicine, University Hospital of Essen, Essen, Germany.
authors.forename: Marion
authors.initials: M
authors.lastname: Lindner
authors.affiliation: Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Klein
authors.affiliation: Department of General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Paul
authors.affiliation: Department of Transplant Medicine, University Hospital Münster, Münster, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Beckebaum
authors.affiliation: Department of Medical Informatics, Biometry and Epidemiology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Mayr
authors.affiliation: Department of Laboratory Medicine, Karolinska Institutet and Karolinska University Laboratory, Stockholm, Sweden.
authors.forename: Anders
authors.initials: A
authors.lastname: Helander
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000534:rehabilitation* / Q000652:urine; D001326:Autogenic Training; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D015331:Cohort Studies; D005240:Feasibility Studies; D005260:Female; D005965:Glucuronates / Q000652:urine; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D010352:Patient Dropouts; D011340:Problem Solving; D011446:Prospective Studies; D011615:Psychotherapy, Group / Q000379:methods*; D012008:Recurrence; D014850:Waiting Lists
chemical_list: D005965:Glucuronates; C093924:ethyl glucuronide