title: A Case of Mesenchymal Chondrosarcoma Arising from the Femoral Vein with 8 Years of Follow-up.
abstract: Mesenchymal chondrosarcoma (MCS) is an infrequent malignancy of bone and soft tissue that is characterized by a peculiar bimorphic histologic pattern with areas of undifferentiated malignant small cells surrounding well-differentiated cartilaginous islands. Involvement of the large vessels is a rare occurrence. Here, we report a case of MCS arising from the femoral vein that was treated by wide-margin resection combined with autogenous vein revascularization and then followed up for 8 years. The long-term postoperative results showed distant metastasis to the pancreas and both lobes of the lung, without recurrence at the primary site. This case indicates that for MCS arising from the femoral vein, although wide-margin resection combined with autogenous vein revascularization may avoid recurrence at the primary site, this treatment strategy has no obvious benefit for controlling long-term distant metastases.
authors.affiliation: Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Institute of Vascular Surgery, Capital Medical University, Beijing, China.
authors.forename: Jianming
authors.initials: J
authors.lastname: Guo
authors.affiliation: Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Institute of Vascular Surgery, Capital Medical University, Beijing, China. Electronic address: 15901598209@163.com.
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Gu
authors.affiliation: Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Institute of Vascular Surgery, Capital Medical University, Beijing, China.
authors.forename: Lianrui
authors.initials: L
authors.lastname: Guo
authors.affiliation: Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Institute of Vascular Surgery, Capital Medical University, Beijing, China.
authors.forename: Zhu
authors.initials: Z
authors.lastname: Tong
authors.affiliation: Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Institute of Vascular Surgery, Capital Medical University, Beijing, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wu
authors.affiliation: Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Institute of Vascular Surgery, Capital Medical University, Beijing, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China; Institute of Vascular Surgery, Capital Medical University, Beijing, China.
authors.forename: Zhonggao
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D018211:Chondrosarcoma, Mesenchymal / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D005268:Femoral Vein / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000737:chemistry / Q000556:secondary*; D008297:Male; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D012501:Saphenous Vein / Q000637:transplantation; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D019043:Vascular Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor