title: Progress in Self-assembling Peptide-based Nanomaterials for Biomedical Applications.
abstract: Self-assembled peptide nanomaterials display the advantageous properties of injectability, biodegradability and biocompatibility. These peptide nanomaterials, by self-assembling, can be widely applied in such fields as drug delivery (small molecules and large molecules), regenerative medicine and nanobiotechnology. In this review, we mainly discuss the properties of these peptide nanomaterials in their physical, chemical and biological aspects. Also discussed are recent advances in their potential applications as drug delivery systems and for uses in regenerative medicine. These current advances show a bright future for the development and clinical applications of self-assembled peptide-based nanotechnology and nanomedicine. However, there are still some big challenges for us to face before these peptide nanomaterials eventually can be used for the treatment of human diseases.
authors.affiliation: Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study , Institute of Pharmacy &Pharmacology,University of South China, Hengyang, 421001,China. yucuiyunusc@hotmail.com.
authors.forename: Cui-Yun
authors.initials: CY
authors.lastname: Yu
authors.forename: Wen
authors.initials: W
authors.lastname: Huang
authors.forename: Zhi-Ping
authors.initials: ZP
authors.lastname: Li
authors.forename: Xiao-Yong
authors.initials: XY
authors.lastname: Lei
authors.forename: Dong-Xiu
authors.initials: DX
authors.lastname: He
authors.forename: Lichun
authors.initials: L
authors.lastname: Sun
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems; D006801:Humans; D050997:Nanomedicine; D049329:Nanostructures / Q000737:chemistry*; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D044968:Regenerative Medicine
chemical_list: D010455:Peptides