title: Palliative parenteral nutrition use in patients with intestinal failure as a consequence of advanced pseudomyxoma peritonei: a case series.
abstract: Pseudomyxoma peritonei (PMP) is a rare condition complicated by intra-abdominal spread that can cause multilevel gastrointestinal (GI) obstruction. Parenteral nutrition (PN) use in the context of palliative care and malignancy remains controversial. We describe the use of palliative PN in three patients with progressive PMP causing multilevel GI obstruction and intestinal failure. All patients received > 90 days of PN. PN was safe in this cohort of patients. However, patient selection and the timing of intervention are important factors when considering the initiation of PN.
authors.affiliation: Department of Gastroenterology, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
authors.forename: B R
authors.initials: BR
authors.lastname: Disney
authors.affiliation: Department of Gastroenterology, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
authors.forename: A
authors.initials: A
authors.lastname: Karthikeyakurup
authors.affiliation: Department of Gastroenterology, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
authors.forename: J
authors.initials: J
authors.lastname: Ratcliffe
authors.affiliation: Department of Gastroenterology, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
authors.forename: J
authors.initials: J
authors.lastname: Jones
authors.affiliation: Department of Gastroenterology, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
authors.forename: P
authors.initials: P
authors.lastname: Deel-Smith
authors.affiliation: Department of Dietetics, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
authors.forename: A
authors.initials: A
authors.lastname: Fairhurst
authors.affiliation: Department of Radiology, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
authors.forename: K
authors.initials: K
authors.lastname: Maleki
authors.affiliation: 1] Department of Gastroenterology, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK [2] Department of Gastroenterology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
authors.forename: S C
authors.initials: SC
authors.lastname: Cooper
mesh_terms: D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D007422:Intestines / Q000503:physiopathology; D008875:Middle Aged; D010166:Palliative Care / Q000379:methods*; D010288:Parenteral Nutrition / Q000379:methods*; D018579:Patient Selection; D010534:Peritoneal Neoplasms / Q000150:complications*; D011553:Pseudomyxoma Peritonei / Q000150:complications*