title: Comparative analysis of cadmium-zincum-telluride cameras dedicated to myocardial perfusion SPECT: A phantom study.
abstract: This investigation used image data generated by an anthropomorphic phantom with a cardiac insert for a comparison between two solid state cameras: D-SPECT and D530c.
  
  
  
  For each camera, two sets (with and without a simulated transmural defect (TD)) of scans were acquired starting from the in vivo standard count statistics in the left ventricle (LV). Other two acquisitions corresponding to 150% and 50% of the reference count statistics were acquired. Five performance indices related to spatial resolution, contrast, and contrast-to-noise ratio (CNR) were analyzed.
  
  
  
  D-SPECT showed a lower LV wall thickness and an inferior sharpness than D530c. No significant differences were found in terms of contrast between LV wall and the inner cavity, TD contrast or CNR. No significant differences were observed in CNR when moving from the reference level of count statistics down to 50% or up to 150% of the counts acquired on the LV.
  
  
  
  Our results show that D-SPECT and D530c have different performances. The lack of differences in the image performance indices along the range of count statistics explored, indicates that there is the possibility for a further reduction in the injected activity and/or the acquisition time, for both systems.
authors.affiliation: Unit of Nuclear Medicine and Department of Cardiology, S. Maugeri Foundation, IRCCS, Scientific Institute of Veruno, Veruno, NO, Italy.
authors.forename: Orazio
authors.initials: O
authors.lastname: Zoccarato
authors.affiliation: Departments of Medical Physics and Nuclear Medicine, University Hospital 'Maggiore della Carità', Novara, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Lizio
authors.affiliation: Department of Nuclear Medicine, Hospital San Raffaele, Milan, Italy.
authors.forename: Annarita
authors.initials: A
authors.lastname: Savi
authors.affiliation: Department of Medical Physics, Polyclinic Agostino Gemelli, Rome, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Indovina
authors.affiliation: Department of Health Sciences, University of Milan and Nuclear Medicine Unit, San Paolo Hospital, Milan, Italy.
authors.forename: Camilla
authors.initials: C
authors.lastname: Scabbio
authors.affiliation: Departments of Medical Physics and Nuclear Medicine, University Hospital 'Maggiore della Carità', Novara, Italy.
authors.forename: Lucia
authors.initials: L
authors.lastname: Leva
authors.affiliation: Department of Health Sciences, University of Milan and Nuclear Medicine Unit, San Paolo Hospital, Milan, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Del Sole
authors.affiliation: Unit of Nuclear Medicine and Department of Cardiology, S. Maugeri Foundation, IRCCS, Scientific Institute of Veruno, Veruno, NO, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Marcassa
authors.affiliation: Departments of Medical Physics and Nuclear Medicine, University Hospital 'Maggiore della Carità', Novara, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Matheoud
authors.affiliation: Department of Health Sciences, University of Milan and Nuclear Medicine Unit, San Paolo Hospital, Milan, Italy.
authors.forename: Michela
authors.initials: M
authors.lastname: Lecchi
authors.affiliation: Departments of Medical Physics and Nuclear Medicine, University Hospital 'Maggiore della Carità', Novara, Italy. marco.brambilla@maggioreosp.novara.it.|Medical Physics Department, University Hospital of Novara, Novara, Italy. marco.brambilla@maggioreosp.novara.it.
authors.forename: Marco
authors.initials: M
authors.lastname: Brambilla
mesh_terms: D002104:Cadmium; D004867:Equipment Design; D019544:Equipment Failure Analysis; D015902:Gamma Cameras; D006801:Humans; D055414:Myocardial Perfusion Imaging / Q000295:instrumentation*; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013691:Tellurium; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation*; D015032:Zinc
chemical_list: C474490:CdZnTe; D002104:Cadmium; D015032:Zinc; D013691:Tellurium
keywords: Cadmium-zincum-telluride; Cardiac; SPECT