title: Intra-operative digital specimen radiology reduces re-operation rates in therapeutic mammaplasty for breast cancer.
abstract: BACKGROUND
  The aim of this study was to evaluate our experience with intra-operative imaging of therapeutic mammaplasty specimens at Edinburgh Breast Unit.
  
  
  METHODS
  A retrospective review was performed of patients who underwent therapeutic mammaplasty in Edinburgh Breast Unit between 2007 and 2013 who had intraoperative specimen radiography.
  
  
  RESULTS
  98 (100%) patients who underwent therapeutic mammaplasty for breast cancer had intra-operative imaging using the faxitron(®) system. 3 out of those 97 (3%) patients had a re-operation because of positive margins confirmed pathologically on cavity excision specimens, but only 1 out of 3 (1%) patients had residual breast cancer present within the re-excision specimen. None required mastectomy. Median age was 58 (range 34-81). Median follow up was 3.1 years (range 6 months - 5.5 years). There was no local recurrence or conversion to mastectomy in this group.
  
  
  CONCLUSIONS
  Complete excision rate in patients who had intra-operative imaging during therapeutic mammaplsty procedure was 97% in our group. Faxitron(®) system is a useful adjunct in helping to achieve low incomplete excision rates.
authors.affiliation: Edinburgh Breast Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK. Electronic address: emajdak@doctors.net.uk.
authors.forename: E J
authors.initials: EJ
authors.lastname: Majdak-Paredes
authors.affiliation: Edinburgh Breast Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.
authors.forename: M V
authors.initials: MV
authors.lastname: Schaverien
authors.affiliation: Edinburgh Breast Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK; Department of Surgical Oncology & Breast Diseases, Polish Mother's Memorial Hospital & Research Institute, Lodz, Poland.
authors.forename: P
authors.initials: P
authors.lastname: Szychta
authors.affiliation: Edinburgh Breast Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.
authors.forename: C
authors.initials: C
authors.lastname: Raine
authors.affiliation: Edinburgh Breast Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK.
authors.forename: J M
authors.initials: JM
authors.lastname: Dixon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007430:Intraoperative Care; D016462:Mammaplasty; D008327:Mammography; D015412:Mastectomy, Segmental / Q000379:methods*; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D018365:Neoplasm, Residual; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies
chemical_list: D018931:Antineoplastic Agents, Hormonal
keywords: Breast cancer; Breast conserving surgery; Breast reconstruction; Therapeutic mammaplasty