title: Chronic kidney disease and heart disease: after 179 years, do we yet understand the link?
abstract: A definitive understanding of the link between heart and kidney disease remains elusive. Bittencourt et al. explore the association between chronic kidney disease (CKD) status, severity of coronary lesions, and clinical outcome in more than 1500 consecutive adult subjects who underwent a clinically indicated coronary computed tomography angiography for the evaluation of the coronary disease. We discuss the implications of their findings in the context of our current understanding of the development of heart disease in CKD.
authors.affiliation: University of Manitoba and Seven Oaks Hospital Research Centre, Winnipeg, Manitoba, Canada.
authors.forename: Navdeep
authors.initials: N
authors.lastname: Tangri
authors.affiliation: University of Manitoba and Seven Oaks Hospital Research Centre, Winnipeg, Manitoba, Canada.
authors.forename: Paul V J
authors.initials: PV
authors.lastname: Komenda
authors.affiliation: University of Manitoba and Seven Oaks Hospital Research Centre, Winnipeg, Manitoba, Canada.
authors.forename: Claudio
authors.initials: C
authors.lastname: Rigatto
mesh_terms: D003327:Coronary Disease / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000453:epidemiology*; D011859:Radiography; D051436:Renal Insufficiency, Chronic / Q000503:physiopathology*