title: Marine-Lenhart syndrome with papillary thyroid carcinoma.
abstract: Graves' disease with accompanying functioning nodules is known as Marine-Lenhart syndrome. Autonomously functioning thyroid nodules (AFTNs) also within Graves' thyroid tissue are almost always bening in nature. A 45-year-old man developed hyperthyroidism due to the coexistence of Graves' disease and AFTN. Total thyroidectomy was performed. The hyperfunctioning nodule with centrally hypoactive foci detected by technetium-99m thyroid scanning was histologically diagnosed as papillary thyroid carcinoma that was 2.5 cm in diameter. We report the presence of papillary thyroid carcinoma within AFTN in patients with Marine-Lenhart syndrome, which has not been reported so far.
authors.affiliation: Department of Endocrinology and Metabolism, Ondokuz Mayis University Medical School, Samsun, Turkey.
authors.forename: Hulusi
authors.initials: H
authors.lastname: Atmaca
authors.affiliation: Department of Endocrinology and Metabolism, Ondokuz Mayis University Medical School, Samsun, Turkey.
authors.forename: Ramis
authors.initials: R
authors.lastname: Çolak
authors.affiliation: Department of Microbiology, Recep Tayyip Erdogan University Medical School, Rize, Turkey.
authors.forename: Zihni Acar
authors.initials: ZA
authors.lastname: Yazici
authors.affiliation: Department of Pathology, Ondokuz Mayis University Medical School, Samsun, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kefeli
authors.affiliation: Department of Nuclear Medicine, Ondokuz Mayis University Medical School, Samsun, Turkey.
authors.forename: Fevziye Canbaz
authors.initials: FC
authors.lastname: Tosun
keywords: Autonomously functioning thyroid nodule; Graves’ disease; Marine-Lenhart syndrome; hyperthyroidism; papillary microcarcinoma; papillary thyroid carcinoma; thyroid scintigraphy; toxic nodular goitre