title: Unimolecular micelles of amphiphilic cyclodextrin-core star-like block copolymers for anticancer drug delivery.
abstract: Well-defined star-like amphiphilic polymers composed of a β-cyclodextrin core, from which 21 hydrophobic poly(lactic acid) arms and hydrophilic poly(ethylene glycol) arms are grafted sequentially, form robust and uniform unimolecular micelles that are biocompatible and efficient in the delivery of anticancer drugs.
authors.affiliation: School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore. mfwang@ntu.edu.sg.
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Xu
authors.affiliation: School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore. mfwang@ntu.edu.sg.
authors.forename: Shiying
authors.initials: S
authors.lastname: Liu
authors.affiliation: School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore. mfwang@ntu.edu.sg.
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.affiliation: School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore. mfwang@ntu.edu.sg.
authors.forename: Cangjie
authors.initials: C
authors.lastname: Yang
authors.affiliation: School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore. mfwang@ntu.edu.sg.
authors.forename: Yuejun
authors.initials: Y
authors.lastname: Kang
authors.affiliation: School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459, Singapore. mfwang@ntu.edu.sg.
authors.forename: Mingfeng
authors.initials: M
authors.lastname: Wang
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology; D004317:Doxorubicin / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology; D016503:Drug Delivery Systems; D006367:HeLa Cells; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D019344:Lactic Acid / Q000138:chemical synthesis / Q000737:chemistry*; D008823:Micelles; D011091:Polyesters; D011092:Polyethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D008823:Micelles; D011091:Polyesters; D011108:Polymers; D047392:beta-Cyclodextrins; D019344:Lactic Acid; D011092:Polyethylene Glycols; C033616:poly(lactide); D004317:Doxorubicin