title: Sedation in critically ill patients.
abstract: Sedation in the intensive care unit (ICU) is a topic that has been frequently researched, and debate still exists as to what are the best sedative agents for critically ill patients. There is increasing interest in sleep and circadian rhythm disturbances in the ICU and how they may impact on outcomes. In addition to patient-related and ICU environmental factors that likely impact sleep and circadian rhythm in the ICU, sedative and analgesic medications may also play a role.
authors.affiliation: Department of Psychiatry, Yale-New Haven Hospital, 15 York Street, New Haven, CT 06510, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Oldham
authors.affiliation: Section of Pulmonary, Critical Care & Sleep Medicine, Yale University School of Medicine, PO Box 208057, TAC S425C, New Haven, CT 06520-8057, USA. Electronic address: margaret.pisani@yale.edu.
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Pisani
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D000758:Anesthesia; D021081:Chronobiology Disorders / Q000628:therapy; D016638:Critical Illness; D003693:Delirium / Q000628:therapy; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D007362:Intensive Care Units; D012121:Respiration, Artificial; D012890:Sleep / Q000502:physiology
chemical_list: D000700:Analgesics; D006993:Hypnotics and Sedatives
keywords: Circadian rhythm; Critically ill patients; Delirium; Intensive care unit; Pain; Sedation