title: RNA based viral silencing suppression in plant pararetroviruses.
abstract: The 35S promoter of cauliflower mosaic virus and that of other plant pararetroviruses gives rise to an RNA, which is both a pre-genome and a polycistronic mRNA. The 600 nucleotide long very structured leader of this RNA is also transcribed separately. The resulting 8S RNA is then converted to a double strand giving rise to a huge set of siRNAs, which suppress silencing. In this Mini-Review I discuss how this versatile stretch of 600 nts constitutes a masterpiece of evolution.
authors.affiliation: Botanical Institute, University of Basel Basel, Switzerland ; Friedrich Miescher Institute Basel, Switzerland.
authors.forename: Thomas
authors.initials: T
authors.lastname: Hohn
keywords: POL II; caulimovirus; shunting; siRNA; silencing; silencing suppression; translation; viroid