title: In situ hydroxyapatite nanofiber growth on calcium borate silicate ceramics in SBF and its structural characteristics.
abstract: A novel calcium silicate borate Ca11Si4B2O22 ceramic was firstly prepared by the conventional solid-state reaction. In vitro hydroxyapatite mineralization was investigated by soaking the ceramics in simulated body fluid (SBF) solutions at body temperature (37 °C) for various time periods. Scanning electron microscopy (SEM) and X-ray diffraction analysis (XRD) measurements were applied to investigate the samples before and after the immersion of ceramics in SBF solution. The elemental compositions of a hydroxyapatite layer on the ceramics during the mineralization were confirmed by X-ray energy-dispersive spectra (EDS). Meanwhile, the bending strength and elastic modulus of Ca11Si4B2O22 ceramics were also measured, which indicate that the biomaterials based on Ca11Si4B2O22 ceramics possess bioactivity and might be a potential candidate as biomaterials for hard tissue repair. The bioactive mineralization ability was evaluated on the base of its crystal structural characteristics, i.e., silanol (Si-OH) and B-OH groups can be easily induced on the surface of Ca11Si4B2O22 ceramics soaked in SBF solutions.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.
authors.forename: Yinfu
authors.initials: Y
authors.lastname: Pu
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.
authors.forename: Yanlin
authors.initials: Y
authors.lastname: Huang
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.
authors.forename: Shuyun
authors.initials: S
authors.lastname: Qi
authors.affiliation: Department of Physics and Interdisciplinary Program of Biomedical, Mechanical & Electrical Engineering, Pukyong National University, Busan 608-737, Republic of Korea.
authors.forename: Cuili
authors.initials: C
authors.lastname: Chen
authors.affiliation: Department of Physics and Interdisciplinary Program of Biomedical, Mechanical & Electrical Engineering, Pukyong National University, Busan 608-737, Republic of Korea. Electronic address: hjseo@pknu.ac.kr.
authors.forename: Hyo Jin
authors.initials: HJ
authors.lastname: Seo
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D001826:Body Fluids / Q000187:drug effects; D001881:Borates / Q000737:chemistry*; D017610:Calcium Compounds / Q000737:chemistry*; D002516:Ceramics / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry* / Q000494:pharmacology; D055119:Elastic Modulus; D006244:Hardness; D008422:Materials Testing / Q000379:methods; D057139:Nanofibers / Q000737:chemistry*; D017640:Silicates / Q000737:chemistry*; D014961:X-Ray Diffraction / Q000379:methods
chemical_list: D001672:Biocompatible Materials; D001881:Borates; D017610:Calcium Compounds; D017640:Silicates; C031316:calcium borate; D017886:Durapatite
keywords: Bioactivity; Biomaterials; Calcium silicate borate; Hydroxyapatite; Mineralization