title: Electrochemotherapy as a new approach on pancreatic cancer and on liver metastases.
abstract: Electrochemotherapy is a local non-thermal treatment for cancer ablation. Currently, many studies and case report have investigated the differences in effectiveness of electrochemotherapy with respect to tumor type, chemotherapeutic drug, and route of drug administration. ESOPE trial validated standard operating procedures [SOP] for ECT using the Cliniporator device and demonstrated that ECT is a simple, highly efficacious, and cost-effective treatment of cutaneous and subcutaneous nodules from different primary tumors for cutaneous or superficial lesions. This review has the purpose to summarize current knowledge about clinical effectiveness of electrochemotherapy and future prospects regarding its use on pancreatic cancer and liver metastasis not only.
authors.affiliation: Department of Abdominal Oncology, Division of Medical Oncology, NCI "Fondazione G. Pascale", Naples, Italy. Electronic address: s.tafuto@istitutotumori.na.it.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Tafuto
authors.affiliation: Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, Italy. Electronic address: claudia.vonarx@gmail.com.
authors.forename: Claudia
authors.initials: C
authors.lastname: von Arx
authors.affiliation: Department of Abdominal Oncology, Division of Medical Oncology, NCI "Fondazione G. Pascale", Naples, Italy. Electronic address: chiaradedivitiis@yahoo.com.
authors.forename: Chiara
authors.initials: C
authors.lastname: De Divitiis
authors.affiliation: Department of Abdominal Oncology, Division of Medical Oncology, NCI "Fondazione G. Pascale", Naples, Italy. Electronic address: mauratraceydebellis@alice.it.
authors.forename: Claire Tracey
authors.initials: CT
authors.lastname: Maura
authors.affiliation: Department of Abdominal Oncology, Division of Surgical Oncology, NCI "Fondazione G. Pascale", Naples, Italy. Electronic address: r.palaia@istitutotumori.na.it.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Palaia
authors.affiliation: Department of Abdominal Oncology, Division of Surgical Oncology, NCI "Fondazione G. Pascale", Naples, Italy. Electronic address: v.albino@istitutotumori.na.it.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Albino
authors.affiliation: Department of Diagnostic Imaging, NCI of Naples, "Fondazione G. Pascale", Naples, Italy. Electronic address: r.fusco@istitutotumori.na.it.
authors.forename: Roberta
authors.initials: R
authors.lastname: Fusco
authors.affiliation: Department of Abdominal Oncology, Division of Medical Oncology, NCI "Fondazione G. Pascale", Naples, Italy. Electronic address: massimo.membrini@gmail.com.
authors.forename: Massimo
authors.initials: M
authors.lastname: Membrini
authors.affiliation: Department of Diagnostic Imaging, NCI of Naples, "Fondazione G. Pascale", Naples, Italy. Electronic address: a.petrillo@istitutotumori.na.it.
authors.forename: Antonella
authors.initials: A
authors.lastname: Petrillo
authors.affiliation: Department of Diagnostic Imaging, NCI of Naples, "Fondazione G. Pascale", Naples, Italy. Electronic address: cinzia.granata80@libero.it.
authors.forename: Vincenza
authors.initials: V
authors.lastname: Granata
authors.affiliation: Department of Abdominal Oncology, Division of Surgical Oncology, NCI "Fondazione G. Pascale", Naples, Italy. Electronic address: f.izzo@istitutotumori.na.it.
authors.forename: Francesco
authors.initials: F
authors.lastname: Izzo
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D053672:Electrochemotherapy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D010190:Pancreatic Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents
keywords: Electrochemotherapy; Electroporation; Liver metastasis; Neuroendocrine tumor; Pancreatic cancer