title: Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer.
abstract: BACKGROUND
  The Cancer Genome Atlas (TCGA) offers a multilayered view of genomics and epigenomics data of many human cancer types. However, the retrieval of expression and methylation data from TCGA is a cumbersome and time-consuming task.
  
  
  RESULTS
  Wanderer is an intuitive Web tool allowing real time access and visualization of gene expression and DNA methylation profiles from TCGA. Given a gene query and selection of a TCGA dataset (e.g., colon adenocarcinomas), the Web resource provides the expression profile, at the single exon level, and the DNA methylation levels of HumanMethylation450 BeadChip loci inside or in the vicinity of the queried gene. Graphic and table outputs include individual and summary data as well as statistical tests, allowing the comparison of tumor and normal profiles and the exploration along the genomic locus and across tumor collections.
  
  
  CONCLUSIONS
  Wanderer offers a simple interface to straightforward access to TCGA data, amenable to experimentalists and clinicians without bioinformatics expertise. Wanderer may be accessed at http://maplab.cat/wanderer.
authors.affiliation: Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Ctra. de Can Ruti, camí de les Escoles, s/n, 08916 Badalona, Spain.|Health Research Institute Germans Trias i Pujol (IGTP), Can Ruti Campus, Ctra. de Can Ruti, camí de les Escoles, s/n, 08916 Badalona, Spain.
authors.forename: Anna
authors.initials: A
authors.lastname: Díez-Villanueva
authors.affiliation: Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Ctra. de Can Ruti, camí de les Escoles, s/n, 08916 Badalona, Spain.|Health Research Institute Germans Trias i Pujol (IGTP), Can Ruti Campus, Ctra. de Can Ruti, camí de les Escoles, s/n, 08916 Badalona, Spain.
authors.forename: Izaskun
authors.initials: I
authors.lastname: Mallona
authors.affiliation: Institute of Predictive and Personalized Medicine of Cancer (IMPPC), Ctra. de Can Ruti, camí de les Escoles, s/n, 08916 Badalona, Spain.|Health Research Institute Germans Trias i Pujol (IGTP), Can Ruti Campus, Ctra. de Can Ruti, camí de les Escoles, s/n, 08916 Badalona, Spain.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Peinado