title: [Quinze questions importantes à se poser en oncologie en 2015].
abstract: Cancers can now be classified by multidimensional criteria including tumour site, histology, primary - "driver" - molecular alterations, secondary molecular alterations, characteristics of the immune stroma, and genetic profile of the patient. The development of tools for the characterisation of the cancers, as well as novel molecular and immune therapeutics are evolving at an unprecedented pace. In 2012, a list of future challenges was identified at the occasion of the European Organisation for Research and Treatment of Cancer (EORTC) 50(th) anniversary. Three years after, it is interesting to look back at the questions addressed then and to assess the progress of these questions. We propose here a novel set questions which have emerged from the recent publications in this area.
authors.affiliation: Centre Léon-Berard, & Cancer Research Center of Lyon 28, rue Laennec, 69008 Lyon, France. Electronic address: jean-yves.blay@lyon.unicancer.fr.
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Blay
authors.affiliation: Centre Léon-Berard, & Cancer Research Center of Lyon 28, rue Laennec, 69008 Lyon, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Tredan
authors.affiliation: Centre Léon-Berard, & Cancer Research Center of Lyon 28, rue Laennec, 69008 Lyon, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Ray-Coquard
authors.affiliation: Centre Léon-Berard, & Cancer Research Center of Lyon 28, rue Laennec, 69008 Lyon, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Rivoire
authors.affiliation: Centre Léon-Berard, & Cancer Research Center of Lyon 28, rue Laennec, 69008 Lyon, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Mehlen
authors.affiliation: Centre Léon-Berard, & Cancer Research Center of Lyon 28, rue Laennec, 69008 Lyon, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Puisieux
authors.affiliation: Centre Léon-Berard, & Cancer Research Center of Lyon 28, rue Laennec, 69008 Lyon, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Bachelot
mesh_terms: D005544:Forecasting; D006297:Health Services Accessibility; D006801:Humans; D008495:Medical Oncology / Q000639:trends*; D058990:Molecular Targeted Therapy / Q000639:trends; D009369:Neoplasms / Q000145:classification / Q000235:genetics / Q000628:therapy*; D057285:Precision Medicine / Q000639:trends; D057170:Translational Research, Biomedical / Q000639:trends
keywords: Caractérisation; Challenges for oncology; Défis pour l'oncologie; Molecular; Médecine personnalisée; Personalized medicine; characterisation of tumors; moléculaire des tumeurs