title: Development and implementation of a cleaning standard algorithm to monitor the efficiency of terminal cleaning in removing adenovirus within a pediatric hematopoietic stem cell transplantation unit.
abstract: Adenovirus infections within the hematopoietic stem cell transplantation setting can lead to high rates of mortality and hospital-acquired cases have been associated with environmental reservoirs. To establish both location and levels of environmental adenovirus contamination, 48 cubicles containing 794 surfaces were screened postterminal clean over a 4-year period. After initial cleaning 23% of these sites had detectable adenovirus. These data were then used to develop and implement a cleaning standard algorithm for terminal cleaning that was implemented to ensure cubicles were adenovirus-free before the next patient admission.
authors.affiliation: Department of Microbiology, Camelia Botnar Laboratories, Great Ormond Street Hospital for Children NHS Trust, London, UK. Electronic address: elaine.cloutman-green@gosh.nhs.uk.
authors.forename: Elaine
authors.initials: E
authors.lastname: Cloutman-Green
authors.affiliation: Healthy Infrastructure Research Group, Department of Civil, Environmental, and Geomatic Engineering, University College London, London, UK.
authors.forename: Melisa
authors.initials: M
authors.lastname: Canales
authors.affiliation: Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford, UK.
authors.forename: Louise
authors.initials: L
authors.lastname: Pankhurst
authors.affiliation: Department of Microbiology, Camelia Botnar Laboratories, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Tessia
authors.initials: T
authors.lastname: Evenor
authors.affiliation: Waltham Forest Clinical Commissioning Group, London, UK.
authors.forename: Deirdre
authors.initials: D
authors.lastname: Malone
authors.affiliation: Infectious Diseases and Microbiology Unit, Institute of Child Health, University College London, London, UK.
authors.forename: Nigel
authors.initials: N
authors.lastname: Klein
authors.affiliation: Healthy Infrastructure Research Group, Department of Civil, Environmental, and Geomatic Engineering, University College London, London, UK.
authors.forename: Lena
authors.initials: L
authors.lastname: Ciric
authors.affiliation: Department of Microbiology, Camelia Botnar Laboratories, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: John C
authors.initials: JC
authors.lastname: Hartley
mesh_terms: D000258:Adenovirus Infections, Human / Q000517:prevention & control* / Q000821:virology; D000260:Adenoviruses, Human / Q000235:genetics / Q000302:isolation & purification*; D000465:Algorithms; D003428:Cross Infection / Q000517:prevention & control* / Q000821:virology; D004783:Environmental Microbiology; D004784:Environmental Monitoring; D006268:Health Facilities; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006757:Hospital Units; D006797:Housekeeping, Hospital; D006801:Humans; D015278:Intensive Care Units, Pediatric; D015233:Models, Statistical
keywords: Health care environment; Healthcare associated infection; Hematology/oncology