title: Safety of Polyacrylamide 1.5% Left in Anterior Chamber in Combined Phacoemulsification and Pars Plana Vitrectomy Surgery.
abstract: To evaluate safety, efficacy and postoperative characteristics of polyacrylamide 1.5% ophthalmic viscosurgical device (OVD) left in anterior chamber during and at the end of combined phacoemulsification and pars plana vitrectomy surgery.
  
  
  
  This prospective study comprised 20 eyes that received combined phacoemulsification and pars plana vitrectomy performed by the same surgeon. Polyacrylamide 1.5% was left in anterior chamber at the end of the surgery. Preoperative and postoperative examinations (4, 12 and 24 hours; 14 days; 1 and 3 months) included measurement of intraocular pressure (IOP), central corneal thickness (CCT), endothelial cell density and assessment of any ocular adverse reactions.
  
  
  
  Four of the 20 patients (20%) showed increased IOP at hours postoperatively and needed medical treatment for IOP control. There was no significant difference in IOP between the preoperative visit and postoperative 3 months (p > 0.05). CCT measurements were similar between preoperative and postoperative visits (p > 0.05). A mean endothelial cell density loss of 6.7% was observed at postoperative day 14, however there was no change after this visit.
  
  
  
  Polyacrylamide 1.5% is safe, well-tolerated and protective in eyes undergoing combined phacoemulsification and pars plana vitrectomy.
authors.affiliation: a Department of Ophthalmology , Gazi University Medical Faculty , Ankara , Turkey .|b Department of Ophthalmology , Sorgun State Hospital , Yozgat , Turkey and.
authors.forename: Emine Esra
authors.initials: EE
authors.lastname: Karaca
authors.affiliation: a Department of Ophthalmology , Gazi University Medical Faculty , Ankara , Turkey .
authors.forename: Şengül
authors.initials: Ş
authors.lastname: Özdek
authors.affiliation: a Department of Ophthalmology , Gazi University Medical Faculty , Ankara , Turkey .
authors.forename: Mehmet Cüneyt
authors.initials: MC
authors.lastname: Özmen
authors.affiliation: c Department of Ophthalmology , Cumhuriyet University Medical Faculty , Sivas , Turkey.
authors.forename: Ayhan
authors.initials: A
authors.lastname: Dursun
authors.affiliation: a Department of Ophthalmology , Gazi University Medical Faculty , Ankara , Turkey .
authors.forename: Nuriye Gökçen
authors.initials: NG
authors.lastname: Yalçın
mesh_terms: D000180:Acrylic Resins / Q000008:administration & dosage*; D000328:Adult; D000368:Aged; D000867:Anterior Chamber / Q000000981:diagnostic imaging / Q000187:drug effects*; D002386:Cataract / Q000150:complications*; D003316:Corneal Diseases / Q000517:prevention & control*; D005260:Female; D005427:Flocculation; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control*; D011184:Postoperative Period; D011446:Prospective Studies; D012164:Retinal Diseases / Q000150:complications / Q000601:surgery; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*; D055815:Young Adult; D000099166:Polyacrylamides
chemical_list: D000180:Acrylic Resins; D000099166:Polyacrylamides
keywords: Combined cataract and pars plana vitrectomy; intraocular pressure; ophthalmic viscosurgical device; polyacrylamide; viscoelastic