title: From Here to Eternity--The Theory and Practice of a Really Long Experiment.
abstract: In February 1988, Richard Lenski set up 12 replicate populations of a single genotype of Escherichia coli in a simple nutrient medium. He has been following their evolution ever since. Here, Lenski answers provocative questions from Jeremy Fox about his iconic "Long-Term Evolution Experiment" (LTEE). The LTEE is a remarkable case study of the interplay of determinism and chance in evolution-and in the conduct of science.
authors.affiliation: Department of Biological Sciences, University of Calgary, Calgary, Canada.
authors.forename: Jeremy W
authors.initials: JW
authors.lastname: Fox
authors.affiliation: Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Lenski
mesh_terms: D005075:Biological Evolution; D004926:Escherichia coli; D012107:Research Design