title: Fecal microbiota transplantation restores dysbiosis in patients with methicillin resistant Staphylococcus aureus enterocolitis.
abstract: BACKGROUND
  Nosocomial Methicillin-resistant Staphylococcus aureus (MRSA) enteritis is rare but can be fatal unless it is detected at an early stage and treated effectively. Dysbiosis of the gut is one of the leading reasons of MRSA enteritis. Fecal microbiota transplantation (FMT) is a burgeoning treatment to rectify this imbalance. But the impact of FMT on MRSA enterocoitis is still unknown yet.
  
  
  METHODS
  A total of 5 patients diagnosed as MRSA enteritis during the early postoperative period were given vancomycin 2 g/day for 3 days and FMT for three continuous days as a standard treatment.
  
  
  RESULTS
  There was a 100% clinical response rate that all the symptoms resulting from MRSA enterocolitis disappeared and MRSA in the feces eliminated clearly. The microbiota profile in feces of the patients also regained balance.
  
  
  CONCLUSIONS
  FMT can be a preferential measure to restore the dysbiosis caused by MSRA enterocolitis.
authors.affiliation: Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, #305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China. dr_betty@126.com.
authors.forename: Yao
authors.initials: Y
authors.lastname: Wei
authors.affiliation: Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, #305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China. yuhang100@163.com.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Gong
authors.affiliation: Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, #305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China. yuwenchen613@163.com.
authors.forename: Weiming
authors.initials: W
authors.lastname: Zhu
authors.affiliation: Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, #305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China. dongguo@nju.edu.cn.
authors.forename: Dong
authors.initials: D
authors.lastname: Guo
authors.affiliation: Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, #305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China. dr_gulili@163.com.
authors.forename: Lili
authors.initials: L
authors.lastname: Gu
authors.affiliation: Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, #305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China. liningrigs@vip.sina.com.
authors.forename: Ning
authors.initials: N
authors.lastname: Li
authors.affiliation: Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, #305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China. weiyao131415@163.com.
authors.forename: Jieshou
authors.initials: J
authors.lastname: Li
mesh_terms: D000328:Adult; D002648:Child; D003131:Combined Modality Therapy; D003428:Cross Infection / Q000188:drug therapy; D064806:Dysbiosis / Q000382:microbiology / Q000628:therapy*; D004760:Enterocolitis / Q000382:microbiology / Q000628:therapy*; D000069467:Fecal Microbiota Transplantation; D005243:Feces / Q000382:microbiology; D005260:Female; D000069196:Gastrointestinal Microbiome / Q000502:physiology*; D006801:Humans; D008297:Male; D016106:Methicillin Resistance / Q000187:drug effects; D055624:Methicillin-Resistant Staphylococcus aureus / Q000254:growth & development; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000382:microbiology / Q000628:therapy*; D014640:Vancomycin / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D014640:Vancomycin