title: Validation of the rapid eye movement sleep behavior disorder screening questionnaire in China.
abstract: We validated the Chinese version of the rapid eye movement sleep behavior disorder (RBD) screening questionnaire (RBDSQ) and calculated its cut-off value for idiopathic or symptomatic sleep behavior disorders (iRBD or sRBD) in Chinese people. Patients with RBD (n=63) and controls (n=165) were enrolled. After all subjects had completed a structured interview, the Chinese version of the RBDSQ and the video polysomnography test, we evaluated the reliability, areas under the curves and the best cut-off values of the RBDSQ and investigated the utility of RBDSQ for iRBD and sRBD in China. We found that Cronbach's alpha was 0.769 and the test-retest reliability was 0.916. RBDSQ scores in iRBD and sRBD patients were similar and higher than those in controls. A total of five points represented the best cut-off value for detecting all RBD patients. In Parkinson's disease, a total score of six points represented the best cut-off value for detecting sRBD. There was no statistically significant difference in total RBDSQ score between iRBD and sRBD, or male and female patients. There was no significant correlation between the RBDSQ score and duration or severity of RBD symptoms. The Chinese version of the RBDSQ had high sensitivity, specificity and reliability and could be used as a tool for screening RBD patients in China.
authors.affiliation: Department of Neurology, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Sleep Center, Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Zong-Wen
authors.initials: ZW
authors.lastname: Wang
authors.affiliation: Department of Neurology, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, China.
authors.forename: Yue-Chang
authors.initials: YC
authors.lastname: Yang
authors.affiliation: Sleep Center, Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors.forename: Hui-Juan
authors.initials: HJ
authors.lastname: Wu
authors.affiliation: Department of Neurology, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, China.
authors.forename: Hong-Yi
authors.initials: HY
authors.lastname: Zhao
authors.affiliation: Department of Neurology, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, China. Electronic address: zhaozx@medmail.com.cn.
authors.forename: Zhong-Xin
authors.initials: ZX
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000368:Aged; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications*; D017286:Polysomnography; D020187:REM Sleep Behavior Disorder / Q000175:diagnosis* / Q000209:etiology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires / Q000592:standards*
keywords: Parkinson’s disease; RBDSQ; REM sleep behavior disorder; Validation study