title: Top 100 bestselling drugs represent an arena struggling for new FDA approvals: drug age as an efficiency indicator.
abstract: We analyzed a list of the top 100 bestselling drugs as a struggling market for new FDA approvals. Using the time from drug approval by the FDA as a measure of drug age, our analysis showed that the top 100 bestselling drugs are getting older. This reflects the stalled launch of new drugs into the market during recent years.
authors.affiliation: Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland. Electronic address: jaroslaw.polanski@us.edu.pl.
authors.forename: Jaroslaw
authors.initials: J
authors.lastname: Polanski
authors.affiliation: Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Bogocz
authors.affiliation: Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Tkocz
mesh_terms: D003132:Commerce / Q000706:statistics & numerical data*; D017277:Drug Approval / Q000191:economics*; D015195:Drug Design; D004345:Drug Industry / Q000191:economics; D006801:Humans; D004364:Pharmaceutical Preparations / Q000191:economics*; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D004364:Pharmaceutical Preparations