title: Back to 2D Culture for Ground State of Intestinal Stem Cells.
abstract: Generating highly uniform clonogenic stem cell populations has been remarkably difficult with stem cells from human small and large intestine. A recent report by Wang et al. (2015) demonstrated homogeneous expansion of human fetal intestinal stem cells, providing a new culture system to understand self-renewing mechanisms of intestinal stem cells.
authors.affiliation: Department of Gastroenterology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
authors.forename: Mariko
authors.initials: M
authors.lastname: Shimokawa
authors.affiliation: Department of Gastroenterology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address: t.sato@a7.keio.jp.
authors.forename: Toshiro
authors.initials: T
authors.lastname: Sato
mesh_terms: D006801:Humans; D007422:Intestines / Q000166:cytology*; D013234:Stem Cells / Q000166:cytology* / Q000378:metabolism*