title: Fluorophore ATCUN complexes: combining agent and probe for oxidative DNA cleavage.
abstract: DNA can be oxidatively cleaved by copper complexes of the ATCUN peptide (amino terminal Cu(II)- and Ni(II)-binding motif). In order to investigate the fate of the metal ion throughout this process, we have exploited quenching/dequenching effects of conjugated fluorophores.
authors.affiliation: Institut für Chemie und Biochemie, Freie Universität Berlin, Fabeckstr. 34/36, 14195 Berlin, Germany. nora.kulak@fu-berlin.de.
authors.forename: C
authors.initials: C
authors.lastname: Wende
authors.forename: N
authors.initials: N
authors.lastname: Kulak
mesh_terms: D020816:Amino Acid Motifs; D003300:Copper / Q000737:chemistry*; D053837:DNA Cleavage; D005456:Fluorescent Dyes / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D010084:Oxidation-Reduction; D010455:Peptides / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D010455:Peptides; D003300:Copper; D009532:Nickel