title: Hydroxyurea treatment does not increase blood viscosity and improves red blood cell rheology in sickle cell anemia.
authors.affiliation: Unité Transversale de la Drépanocytose, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Lemonne
authors.affiliation: Inserm UMR 1134, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe Laboratoire d'Excellence GR-Ex « The red cell: from genesis to death », PRES Sorbonne Paris Cité, 75015, Paris, France.
authors.forename: Keyne
authors.initials: K
authors.lastname: Charlot
authors.affiliation: Inserm UMR 1134, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe Laboratoire d'Excellence GR-Ex « The red cell: from genesis to death », PRES Sorbonne Paris Cité, 75015, Paris, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Waltz
authors.affiliation: Department of Medicine, Cardeza Foundation for Hematologic Research, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
authors.forename: Samir K
authors.initials: SK
authors.lastname: Ballas
authors.affiliation: Inserm UMR 1134, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe Laboratoire d'Excellence GR-Ex « The red cell: from genesis to death », PRES Sorbonne Paris Cité, 75015, Paris, France.
authors.forename: Yann
authors.initials: Y
authors.lastname: Lamarre
authors.affiliation: Laboratoire de génétique moléculaire, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe.
authors.forename: Ketty
authors.initials: K
authors.lastname: Lee
authors.affiliation: Inserm UMR 1134, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe Laboratoire d'Excellence GR-Ex « The red cell: from genesis to death », PRES Sorbonne Paris Cité, 75015, Paris, France.
authors.forename: Régine
authors.initials: R
authors.lastname: Hierso
authors.affiliation: Inserm UMR 1134, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe Laboratoire d'Excellence GR-Ex « The red cell: from genesis to death », PRES Sorbonne Paris Cité, 75015, Paris, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Connes
authors.affiliation: Unité Transversale de la Drépanocytose, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe.
authors.forename: Maryse
authors.initials: M
authors.lastname: Etienne-Julan
authors.affiliation: Inserm UMR 1134, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe Laboratoire d'Excellence GR-Ex « The red cell: from genesis to death », PRES Sorbonne Paris Cité, 75015, Paris, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Romana
authors.affiliation: Inserm UMR 1134, Hôpital Ricou, CHU de Pointe-à-Pitre, Guadeloupe Laboratoire d'Excellence GR-Ex « The red cell: from genesis to death », PRES Sorbonne Paris Cité, 75015, Paris, France Institut Universitaire de France, Paris, France Laboratoire CRIS EA647, Section "Vascular Biology and Red Blood Cell", Université Claude Bernard Lyon 1, France pconnes@yahoo.fr.
authors.forename: Philippe
authors.initials: P
authors.lastname: Connes
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000097:blood* / Q000188:drug therapy*; D000986:Antisickling Agents / Q000494:pharmacology / Q000627:therapeutic use; D001809:Blood Viscosity / Q000187:drug effects*; D004907:Erythrocyte Deformability / Q000187:drug effects*; D005260:Female; D006400:Hematocrit; D006801:Humans; D006918:Hydroxyurea / Q000494:pharmacology* / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D000986:Antisickling Agents; D006918:Hydroxyurea
keywords: haemorheology; hydroxyurea; sickle cell disease