title: Clinical aspects of influenza A(H1N1)pdm09 cases reported during the pandemic in Brazil, 2009-2010.
abstract: OBJECTIVE
  To describe the clinical aspects of cases of influenza A(H1N1)pdm09 in Brazil.
  
  
  METHODS
  A descriptive study of cases reported in Sistema de Informação de Agravos de Notificação (SINAN), 2009-2010.
  
  
  RESULTS
  As the final classification, we obtained 53,797 (56.79%) reported cases confirmed as a new influenza virus subtype, and 40,926 (43.21%) cases discarded. Fever was the most common sign, recorded in 99.74% of the confirmed and 98.92% of the discarded cases. Among the confirmed cases, the presence of comorbidities was reported in 32.53%, and in 38.29% of the discarded cases. The case fatality rate was 4.04%; 3,267 pregnant women were confirmed positive for influenza A new viral subtype and 2,730 of them were cured. The case fatality rate of pregnant women was 6.88%.
  
  
  CONCLUSIONS
  The findings suggested concern of the health system with pregnant women, and patients with comorbidities and quality of care may have favored a lower mortality. We recommend that, when caring for patients with severe respiratory symptoms, with comorbidities, or pregnant women, health professionals should consider the need for hospital care, as these factors make up a worse prognosis of infection by the pandemic influenza virus.
authors.affiliation: Instituto de Medicina Tropical de São Paulo, São Paulo, SP, Brazil.
authors.forename: Érika Valeska
authors.initials: ÉV
authors.lastname: Rossetto
authors.affiliation: Instituto de Medicina Tropical de São Paulo, São Paulo, SP, Brazil.
authors.forename: Expedito José de Albuquerque
authors.initials: EJ
authors.lastname: Luna
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D003371:Cough / Q000150:complications; D018563:Disease Notification / Q000706:statistics & numerical data; D005260:Female; D005334:Fever / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications / Q000453:epidemiology*; D055370:Lung Injury / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D058873:Pandemics / Q000706:statistics & numerical data*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D062486:Public Health Surveillance; D012907:Smoking / Q000453:epidemiology*; D055815:Young Adult