title: Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China.
abstract: BACKGROUND
  Chrysotile had been used in asbestos textile workshops in Southeast China but a clear relation to mesothelioma is lacking.
  
  
  METHODS
  All patients diagnosed with mesothelioma from 2003 to 2010 at Yuyao People's Hospital were re-evaluated by multiple expert pathologists with immunohistochemistry and asbestos exposure data were collected.
  
  
  RESULTS
  Of 43 patients with a mesothelioma diagnosis, 19 peritoneal and nine pleural cases were finally diagnosed as mesothelioma. All were females, and the mean age of the patients with peritoneal or pleural mesothelioma was 52.4 and 58.2 years, respectively. All these cases had a history of domestic or occupational exposure to chrysotile. Two-thirds of the patients were from two adjoining towns with multiple small asbestos textile workshops. Contamination of tremolite was estimated to be less than 0.3%.
  
  
  CONCLUSIONS
  This is a report of mesothelioma in women exposed to chrysotile asbestos at home and at work, with an over-representation of peritoneal mesothelioma.
authors.affiliation: Department of Pathology, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province, 315400, China.
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Gao
authors.affiliation: Department of Pathology, Tokyo Women's Medical University, Yachiyo Medical Center, Owada-Shinden 477-96, Yachiyo, Chiba, 276-8524, Japan.
authors.forename: Kenzo
authors.initials: K
authors.lastname: Hiroshima
authors.affiliation: Department of Respiratory Medicine, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province, 315400, China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Wu
authors.affiliation: Department of Respiratory Medicine, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province, 315400, China.
authors.forename: Jixian
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Yuyao Center for Disease Control and Prevention, Yangmingdong Road 129, Yuyao, Ningbo, Zhejiang Province, 315400, China.
authors.forename: Dichu
authors.initials: D
authors.lastname: Shao
authors.affiliation: Department of Gynecology, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province 315400, China.
authors.forename: Huajiang
authors.initials: H
authors.lastname: Shao
authors.affiliation: Department of Radiology, Yuyao People's Hospital, Chendong Road 800, Yuyao, Ningbo, Zhejiang Province, 315400, China.
authors.forename: Hanqing
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of General Thoracic Surgery and Asbestos Disease Center, Chiba Rosai Hospital, Tatsumidaihigashi 2-16, Ichihara, Chiba, 290-0003, Japan.
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Yusa
authors.affiliation: Department of Pathology, Jikei University School of Medicine, Nishi-sinbashi 3-25-8, Minato-ku, Tokyo, Japan.
authors.forename: Takako
authors.initials: T
authors.lastname: Kiyokawa
authors.affiliation: Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan, Kawada-cho 8-1, Shinjuku-ku, Tokyo, 162-8666, Japan.
authors.forename: Makio
authors.initials: M
authors.lastname: Kobayashi
authors.affiliation: Work Environment Research Group, National Institute of Occupational Safety and Health, Nagao 6-21-1, Tama-ku, Kawasaki-shi, Kanagawa, 214-8585, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Shinohara
authors.affiliation: Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology (NTNU), Erling Skjalgssons gt. 1, Trondheim, 7491, Norway.|CancerClinic, Levanger Hospital, Nord-Trøndelag Hospital Trust, Kirkegata 2, 7600, Levanger, Norway.|Department of Oncology, Clinical Cancer Research Center, Aalborg University Hospital, Hobrovej 18-22, 9000 Aalborg, Denmark.
authors.forename: Oluf D
authors.initials: OD
authors.lastname: Røe
authors.affiliation: Zhejiang Academy of Medical Sciences, Tianmushan Road 182, Hangzhou, Zhejiang Province, 310013, China.
authors.forename: Xing
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Asbestos-related Health Damage Relief, Environmental Restoration and Conservation Agency of Japan, Muza Kawasaki Central Tower, Omiya-cho 1310, Saiwai-Ku, Kawasaki-Shi, Kanagawa, 212-8554, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Morinaga
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D001194:Asbestos / Q000009:adverse effects*; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D000086002:Mesothelioma, Malignant; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis / Q000706:statistics & numerical data; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D013783:Textile Industry
chemical_list: D000395:Air Pollutants, Occupational; D001194:Asbestos
keywords: China; asbestos; chrysotile; immunohistochemistry; mesothelioma; woman