title: Immediately loaded dental implants bioactivated with platelet-rich plasma (PRP) placed in maxillary and mandibular region.
abstract: Dental implants have today deeply changed the dental field. In fact, after almost 50 years, the permanent placement of a titanium screw with an attached tooth have, step by step, changed the society's standard toward a permanently replacement of missed or severely damaged teeth. In fact, the host of benefits born from dental implants have affected both patients and dental professionals. The aim of the present study is to report the outcomes of an implant therapy protocol supporting fixed prostheses implanted soon after extractions and loaded with flapless guided surgery by a 3D software planning.
  
  
  
  37 patients, requiring rehabilitation of booth dental arches with a one-to-one technique, were enrolled in a follow-up study plan which established clinical and radiological examinations on the day after surgery, seven months and one year later. Platelet Rich Plasma (PRP), in combination with autogenous bone, organic bone material and organic bone substitutes, was used before implant-prosthetic rehabilitation with an its prompt loading just before the implant insertion phase.
  
  
  
  Definitive restorations were delivered at 6-12 months after surgical procedure. One year after loading there were no dropouts and no failure of the definitive prosthesis. Furthermore, the feedback from patients resulted positive.
  
  
  
  Patients resulted satisfied both aesthetically and functionally regarding these types of prosthetic reconstructions made at the time.
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Inchingolo
authors.affiliation: Departments of Basic Medical Sciences, Neurosciences and Sense organs, University "Aldo Moro", Bari, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Ballini
authors.affiliation: Departments of Biomedical Sciences and Human Oncology, University "Aldo Moro", Bari, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Cagiano
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: A D
authors.initials: AD
authors.lastname: Inchingolo
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Serafini
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: De Benedittis
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Cortelazzi
authors.affiliation: Calabrodental Clinic, Regenerative Medicine Section, Tecnologica Research Institute, Crotone, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Tatullo
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Marrelli
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: A M
authors.initials: AM
authors.lastname: Inchingolo
authors.affiliation: University of Medicine and Pharmacy "Victor Babes" Timisoara, Romania.
authors.forename: D
authors.initials: D
authors.lastname: Vermesan
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Del Corso
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Malcangi
authors.affiliation: Calabrodental Clinic, Regenerative Medicine Section, Tecnologica Research Institute, Crotone, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Diteodoro
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: S A
authors.initials: SA
authors.lastname: Mura
authors.affiliation: Departments of Basic Medical Sciences, Neurosciences and Sense organs, University "Aldo Moro", Bari, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Cantore
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cortelazzi
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Paduanelli
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Resta
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Muollo
authors.affiliation: Departments of Basic Medical Sciences, Neurosciences and Sense organs, University "Aldo Moro", Bari, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Cirulli
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Pettini
authors.affiliation: Department of Morphologic and Surgical Sciences, Insubria University, Varese, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Farronato
authors.affiliation: Departments of Basic Medical Sciences, Neurosciences and Sense organs, University "Aldo Moro", Bari, Italy.
authors.forename: D
authors.initials: D
authors.lastname: De Vito
authors.affiliation: Departments of Biomedical Sciences and Human Oncology, University "Aldo Moro", Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Caprio
authors.affiliation: University of Medicine and Pharmacy "Victor Babes" Timisoara, Romania.
authors.forename: H
authors.initials: H
authors.lastname: Haragus
authors.affiliation: Departments of Interdisciplinary Medicine, University "Aldo Moro", Bari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Dipalma
mesh_terms: D018786:Bone Substitutes; D015921:Dental Implants; D017267:Dental Prosthesis Design / Q000295:instrumentation*; D005500:Follow-Up Studies; D006801:Humans; D017060:Patient Satisfaction; D053657:Platelet-Rich Plasma
chemical_list: D018786:Bone Substitutes; D015921:Dental Implants
keywords: Computerized implant software; Dental implants; Immediate loading; Oral rehabilitation; Platelet-rich plasma