title: Outbreak of colonization by carbapenemase-producing Klebsiella pneumoniae in a neonatal intensive care unit: Investigation, control measures and assessment.
abstract: We describe an outbreak of carbapenemase-producing Klebsiella pneumoniae in a neonatal intensive care unit and assess the effect of infection control measures. Our assessment indicates that active surveillance culture is very useful in identifying multidrug-resistant organisms and its prevention from transmission. Besides contact precaution, environment disinfection, good compliance of hand hygiene, and single-room isolation is very important for preventing transmission of carbapenemase-producing K pneumoniae isolates.
authors.affiliation: Nosocomial Infection Control Department, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Jiong
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Nosocomial Infection Control Department, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Guiping
authors.initials: G
authors.lastname: Li
authors.affiliation: Department of Infectious Diseases, Peking Union Medical College Hospital, Beijing, China. Electronic address: drmaxiaojun@sina.com.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Ma
authors.affiliation: Department of Clinical Laboratory, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Qiwen
authors.initials: Q
authors.lastname: Yang
authors.affiliation: Department of Clinical Laboratory, Peking Union Medical College Hospital, Beijing, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Yi
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D004196:Disease Outbreaks; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017053:Infection Control / Q000379:methods*; D007363:Intensive Care Units, Neonatal; D007710:Klebsiella Infections / Q000453:epidemiology* / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000201:enzymology* / Q000302:isolation & purification; D008297:Male; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase
keywords: Carbapenemase-producing Klebsiella pneumoniae; Infection control; Neonatal intensive care unit; Outbreak