title: [Radionuclide therapy and diagnostics in urology].
abstract: In recent years there has been methodological improvement in established nuclear medicine procedures, such as renal and skeletal scintigraphy and new very specific probes for treatment and diagnosis of urological diseases have been introduced into the clinical routine. New diagnostic methods, such as positron emission tomography (PET) using prostate-specific membrane antigen (PSMA) ligands for highly accurate tumor localization in recurrent prostate cancer have become available in many centers. The very high and selective accumulation of these PSMA ligands in tumor tissue has shown promising therapeutic results. Moreover, since 2013 a new radiopharmaceutical agent, radium-223 dichloride, has been approved for treatment of symptomatic bone metastases of prostate cancer. Better knowledge of indications, benefits and limitations of these procedures will help clinicians to adequately introduce them into patient management. This article summarizes the state of the art in established nuclear medicine procedures for urological disorders and also reports on new diagnostic and therapeutic possibilities.
authors.affiliation: Klinik und Poliklinik für Nuklearmedizin, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Deutschland, wolfgang.fendler@med.uni-muenchen.de.
authors.forename: W P
authors.initials: WP
authors.lastname: Fendler
authors.forename: V
authors.initials: V
authors.lastname: Wenter
authors.forename: C G
authors.initials: CG
authors.lastname: Stief
authors.forename: C
authors.initials: C
authors.lastname: Gratzke
authors.forename: P
authors.initials: P
authors.lastname: Bartenstein
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D009683:Nuclear Medicine / Q000639:trends*; D011868:Radioisotopes / Q000627:therapeutic use*; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D014055:Tomography, Emission-Computed / Q000639:trends*; D014570:Urologic Diseases / Q000000981:diagnostic imaging* / Q000532:radiotherapy*
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals