title: Sleep Patterns During Hospitalization Following Hematopoietic Stem Cell Transplantation.
abstract: OBJECTIVE
  To characterize patient-reported and objective sleep assessments and provide a preliminary examination of the relationships among sleep, quality of life, and demographic or treatment factors.
  
  
  METHODS
  A secondary data analysis using a descriptive-correlational design.
  
  
  METHODS
  University of Illinois Hospital and Health Sciences System.
  
  
  METHODS
  40 patients undergoing a hematopoietic stem cell transplantation (HCT) hospitalized for the conditioning regimen, stem cell infusion, and immediate recovery period.
  
  
  METHODS
  Each patient wore a wrist actigraph continuously from the fourth day following HCT to the eighth day to objectively assess sleep patterns (total sleep time, sleep onset latency, sleep efficiency, wake after sleep onset, and number of awakenings). At the end of the five-day period, patients completed measures of sleep disturbance and quality of life.
  
  
  METHODS
  Objective sleep (total sleep time, sleep onset latency, sleep efficiency, wake after sleep onset, and number of awakenings), subjective sleep (sleep disturbance), and quality of life.
  
  
  RESULTS
  The mean total nighttime sleep (objectively obtained) was 232 minutes (SD = 71 minutes), with 14 patients (35%) sleeping less than three consecutive hours during one or more study days. Age was negatively correlated with patient-reported sleep disturbance. Patient-reported sleep disturbance was significantly associated with length of hospital stay. No correlations were found between patient-reported and objective sleep assessments.
  
  
  CONCLUSIONS
  This study objectively documents inadequate and irregular sleep in hospitalized patients undergoing HCT. Sole reliance on patient-reported sleep assessments may not represent the full extent of the problem.
  
  
  CONCLUSIONS
  Attempts to streamline care during the night by not waking patients for routine care unless indicated by the patient's condition (as advocated by the American Academy of Nursing) and providing supportive care for symptoms (such as diarrhea) during the night may reduce the number of awakenings and possibly improve overall sleep quality.
authors.forename: Eileen Danaher
authors.initials: ED
authors.lastname: Hacker
authors.affiliation: University of Illinois at Chicago.
authors.forename: Mary Catherine
authors.initials: MC
authors.lastname: Kapella
authors.affiliation: University of Illinois at Chicago.
authors.forename: Chang
authors.initials: C
authors.lastname: Park
authors.affiliation: University of Illinois at Chicago.
authors.forename: Carol E
authors.initials: CE
authors.lastname: Ferrans
authors.affiliation: Division of Acute, Critical, and Long-Term Care, School of Nursing, University of Michigan in Ann Arbor.
authors.forename: Janet L
authors.initials: JL
authors.lastname: Larson
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007087:Illinois; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D011788:Quality of Life; D012893:Sleep Wake Disorders / Q000209:etiology*; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
keywords: hematopoietic stem cell transplantation; hospitalization; sleep; sleep disturbances