title: Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis.
abstract: Granulomatous cutaneous T-cell lymphomas (CTCL) and lymphomatoid granulomatosis are considered granulomatous lymphoproliferative disorders. The most common types of granulomatous CTCL are granulomatous mycosis fungoides and granulomatous slack skin. Lymphomatoid granulomatosis is a rare Epstein-Barr virus driven lymphoproliferative disorder. This article reviews the etiopathogenesis, clinical presentation, systemic associations, and management of both granulomatous slack skin syndrome and lymphomatoid granulomatosis.
authors.affiliation: MD Anderson Cancer Center, Department of Dermatology, 1400 Pressler Street FCT11.6074, Houston, TX 77030, USA.
authors.forename: Pamela
authors.initials: P
authors.lastname: Gangar
authors.affiliation: MD Anderson Cancer Center, Department of Dermatology, 1400 Pressler Street FCT11.6074, Houston, TX 77030, USA. Electronic address: Sangeetha.venkatarajan@gmail.com.
authors.forename: Sangeetha
authors.initials: S
authors.lastname: Venkatarajan
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D062109:Dermatologic Surgical Procedures; D004854:Herpesvirus 4, Human; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D016898:Interferon-alpha / Q000627:therapeutic use; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis / Q000628:therapy*; D008230:Lymphomatoid Granulomatosis / Q000175:diagnosis / Q000628:therapy* / Q000821:virology; D000069283:Rituximab / Q000627:therapeutic use; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000628:therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D000970:Antineoplastic Agents; D007155:Immunologic Factors; D016898:Interferon-alpha; D000069283:Rituximab
keywords: EBV-positive lymphoproliferative disorder; Granulomatous cutaneous T-cell lymphoma; Granulomatous mycosis fungoides; Granulomatous slack skin; Lymphomatoid granulomatosis