title: [Statins for children with hypercholesterolemia].
abstract: In the different types of children's hypercholesterolemia, some severe inherited monogenic forms, transmitted as a dominant trait, carry a high risk of early cardiovascular events in young adults and a decrease in life expectancy, warranting the initiation of a preventive cholesterol-lowering treatment early in childhood. As in adult patients, statins are the first-line drugs. The purpose of this article is to review the existing recommendations for their indications in children, their benefits, their tolerance, as well as their prescription and monitoring modalities.
authors.affiliation: Nutrition et gastro-entérologie pédiatriques, hôpital Armand-Trousseau, AP-HP, UPMC, 26, avenue Arnold-Netter, 75012 Paris 06, France. Electronic address: jean-philippe.girardet@trs.aphp.fr.
authors.forename: J-P
authors.initials: JP
authors.lastname: Girardet
mesh_terms: D002648:Child; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D006937:Hypercholesterolemia / Q000188:drug therapy*; D017410:Practice Guidelines as Topic
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors