title: Synthesis and unique reversible splitting of 14-membered cyclic aminomethylphosphines on to 7-membered heterocycles.
abstract: A novel type of 14-membered cyclic polyphosphine, namely 1,8-diaza-3,6,10,13-tetraphosphacyclotetradecanes 2a–4ahas been synthesized by the condensation of 1,2-bis(phenylphosphino)ethane, formaldehyde and alkylamines (isopropylamine, ethylamine and cyclohexylamine) as a RRRR/SSSS-stereoisomer. The structure of macrocycle 2a was investigated by NMR-spectroscopy and X-ray crystal structure analysis. The unique reversible processes of macrocycles 2a–4a splitting onto the corresponding rac- (2b–4b) and meso- (2c–4c) stereoisomers of 1-aza-3,6-diphosphacycloheptanes were discovered.
authors.affiliation: A.E. Arbuzov Institute of Organic and Physical Chemistry of KSC RAS, Arbuzov str. 8, Kazan, 420088, Russian Federation. elli@iopc.ru.
authors.forename: Elvira I
authors.initials: EI
authors.lastname: Musina
authors.forename: Tatiana I
authors.initials: TI
authors.lastname: Fesenko
authors.forename: Igor D
authors.initials: ID
authors.lastname: Strelnik
authors.forename: Fedor M
authors.initials: FM
authors.lastname: Polyancev
authors.forename: Shamil K
authors.initials: SK
authors.lastname: Latypov
authors.forename: Peter
authors.initials: P
authors.lastname: Lönnecke
authors.forename: Evamarie
authors.initials: E
authors.lastname: Hey-Hawkins
authors.forename: Andrey A
authors.initials: AA
authors.lastname: Karasik
authors.forename: Oleg G
authors.initials: OG
authors.lastname: Sinyashin
mesh_terms: D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D003508:Cycloheptanes / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D008745:Methylation; D008958:Models, Molecular; D010720:Phosphines / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000588:Amines; D003508:Cycloheptanes; D047028:Macrocyclic Compounds; D010720:Phosphines