title: The confounding effect of the development of idiopathic orthostatic edema and thyrotoxcosis on weight fluctuation related to effects on free water clearance in a woman with long-standing surgically induced panhypopituitarism and diabetes insipidus.
abstract: OBJECTIVE
  To evaluate the effect of idiopathic orthostatic edema and the effect of thyrotoxicosis on weight fluctuation and fluid retention in the presence of surgically induced panhypopituitarism and diabetes insipidus controlled with hormone replacement.
  
  
  METHODS
  Dextroamphetamine sulfate was used for weight gain when no other etiologic factor was found. Methimazole was used when weight loss occurred when serum T4 and free T4 indicated thyrotoxicosis.
  
  
  RESULTS
  Sympathomimetic amine therapy very effectively controlled the weight gain and methimazole controlled the weight loss.
  
  
  CONCLUSIONS
  Hypopituitarism and diabetes insipidus controlled with hormone replacement do not protect against fluid retention from idiopathic edema.
authors.forename: J H
authors.initials: JH
authors.lastname: Check
authors.forename: J
authors.initials: J
authors.lastname: Weidner
mesh_terms: D050034:Antidiuretic Agents / Q000627:therapeutic use*; D013956:Antithyroid Agents / Q000627:therapeutic use*; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D003913:Dextroamphetamine / Q000627:therapeutic use*; D003919:Diabetes Insipidus / Q000150:complications / Q000188:drug therapy*; D004487:Edema / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000150:complications / Q000188:drug therapy*; D008713:Methimazole / Q000627:therapeutic use*; D008875:Middle Aged; D011187:Posture; D013566:Sympathomimetics / Q000627:therapeutic use*; D013971:Thyrotoxicosis / Q000150:complications / Q000188:drug therapy*; D015430:Weight Gain; D015431:Weight Loss
chemical_list: D050034:Antidiuretic Agents; D013956:Antithyroid Agents; D013566:Sympathomimetics; D008713:Methimazole; D003894:Deamino Arginine Vasopressin; D003913:Dextroamphetamine