title: An Organic Field-effect Transistor with an Extended-gate Electrode Capable of Detecting Human Immunoglobulin A.
abstract: We herein report on the development of an extended-gate type organic field-effect transistor (OFET)-based immunosensor for the detection of human immunoglobulin A (IgA). The titration results of IgA exhibited shifts in the transfer characteristics of the OFET sensor device with increasing IgA concentration. A linear detection range from 0 to 10 μg/mL was realized with a detection limit of 2.1 μg/mL, indicating that the OFET-based immunosensor can be potentially applied to the monitoring of infectious diseases and psychological stress in daily life.
authors.affiliation: Research Center for Organic Electronics (ROEL), Graduate School of Science and Engineering, Yamagata University.
authors.forename: Tsukuru
authors.initials: T
authors.lastname: Minamiki
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Minami
authors.forename: Yui
authors.initials: Y
authors.lastname: Sasaki
authors.forename: Ryoji
authors.initials: R
authors.lastname: Kurita
authors.forename: Osamu
authors.initials: O
authors.lastname: Niwa
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Wakida
authors.forename: Shizuo
authors.initials: S
authors.lastname: Tokito
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D004563:Electrochemistry; D004566:Electrodes; D006801:Humans; D007118:Immunoassay; D007070:Immunoglobulin A / Q000032:analysis* / Q000737:chemistry; D057230:Limit of Detection; D009930:Organic Chemicals / Q000737:chemistry*; D014173:Transistors, Electronic; D014867:Water / Q000737:chemistry
chemical_list: D007070:Immunoglobulin A; D009930:Organic Chemicals; D014867:Water