title: Deficient regulatory B cells in human chronic graft-versus-host disease.
abstract: Human chronic graft-versus-host disease (cGVHD) is a frequent and disabling complication of allogeneic hematopoietic stem cell transplantation. Regulatory B cells (Bregs) are IL-10-producing B cells that are able to inhibit the innate and adaptive immune responses. We have recently demonstrated a defect in regulatory B cells in human cGVHD.
authors.affiliation: Service de Dermatologie; Hôpital Saint-Louis ; Paris, France ; INSERM UMRS 976; Laboratoire "Oncodermatology; Immunology and Cutaneous Stem Cells"; Université Paris VII Sorbonne Paris Cité; Hôpital Saint-Louis ; Paris, France.
authors.forename: Adèle
authors.initials: A
authors.lastname: de Masson
authors.affiliation: Service d'Hématologie Greffes; INSERM UMRS 1160; Université Paris VII Sorbonne Paris Cité; Hôpital Saint-Louis ; Paris, France.
authors.forename: Gérard
authors.initials: G
authors.lastname: Socié
authors.affiliation: Service de Dermatologie; Hôpital Saint-Louis ; Paris, France ; INSERM UMRS 976; Laboratoire "Oncodermatology; Immunology and Cutaneous Stem Cells"; Université Paris VII Sorbonne Paris Cité; Hôpital Saint-Louis ; Paris, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Bagot
authors.affiliation: INSERM UMRS 976; Laboratoire "Oncodermatology; Immunology and Cutaneous Stem Cells"; Université Paris VII Sorbonne Paris Cité; Hôpital Saint-Louis ; Paris, France.
authors.forename: Armand
authors.initials: A
authors.lastname: Bensussan
authors.affiliation: Service de Dermatologie; Hôpital Saint-Louis ; Paris, France ; INSERM UMRS 976; Laboratoire "Oncodermatology; Immunology and Cutaneous Stem Cells"; Université Paris VII Sorbonne Paris Cité; Hôpital Saint-Louis ; Paris, France.
authors.forename: Jean-David
authors.initials: JD
authors.lastname: Bouaziz
keywords: allogeneic stem cell transplantation; chronic graft-versus-host disease; interleukin-10; regulatory B cells