title: Fine-needle-aspiration cytology of a proximal type epithelioid sarcoma: A case report.
abstract: Epithelioid sarcoma is a rare mesenchymal neoplasm, with an as yet unidentified cell of origin. Two subtypes of epithelioid sarcoma, distal/classic and proximal/large cell type, are recognized in the literature; with the proximal-type having a lower incidence amongst the two. Here, we present a case of proximal-type epithelioid sarcoma in a previously healthy young man. Fine-needle-aspiration of a large axillary mass was performed for diagnosis. The cytologic findings included a dispersed population of large epithelioid to polyhedral cells with abundant cytoplasm. Immunohistochemical staining showed coexpression of keratin and vimentin, as well as loss of INI1 staining, consistent with an epithelioid sarcoma, proximal subtype.
authors.affiliation: Resident in Anatomic and Clinical Pathology, Department of Pathology, University of North Carolina, Chapel Hill, North Carolina.
authors.forename: Avani A
authors.initials: AA
authors.lastname: Pendse
authors.affiliation: Resident in Anatomic and Clinical Pathology, Department of Pathology, University of North Carolina, Chapel Hill, North Carolina.
authors.forename: Leslie G
authors.initials: LG
authors.lastname: Dodd
mesh_terms: D000328:Adult; D001365:Axilla / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000378:metabolism; D044963:Biopsy, Fine-Needle; D003581:Cytodiagnosis; D006801:Humans; D007633:Keratins / Q000378:metabolism; D008198:Lymph Nodes / Q000166:cytology / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D012509:Sarcoma / Q000175:diagnosis* / Q000473:pathology; D014746:Vimentin / Q000378:metabolism; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor; D014746:Vimentin; D007633:Keratins
keywords: INI1; epithelioid sarcoma; fine-needle aspiration; proximal epithelioid sarcoma