title: Hepatitis C: Prevalence of serologic markers and risk factors in blood donors at a large blood centre in South-eastern Brazil (2007-2010).
abstract: This study aimed to evaluate the trends of HCV seropositivity rates in first time blood donors from a reference blood centre in Southeast Brazil. Data from the period of 2007-2010 were analysed according to anti-HCV antibodies, donor demographic characteristics and type of donation. There was a marked and continuous decline in prevalence in the analysed period, and in 93,534 first time donors, the prevalence of anti-HCV was 0.09%. Anti-HCV were associated with less education and older age (≥ 35 years). The rates of anti-HCV observed in the present study were lower than in Brazil, but considerably higher than developed countries.
authors.affiliation: Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Franciane
authors.initials: F
authors.lastname: Mendes-Oliveira
authors.affiliation: Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Eduarda
authors.initials: E
authors.lastname: Bolina-Santos
authors.affiliation: Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Tassila
authors.initials: T
authors.lastname: Salomon
authors.affiliation: Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Carolina
authors.initials: C
authors.lastname: Miranda
authors.affiliation: Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Júnia
authors.initials: J
authors.lastname: Cioffi
authors.affiliation: Universidade de São Paulo, São Paulo, Minas Gerais, Brazil.
authors.forename: Ester
authors.initials: E
authors.lastname: Sabino
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Edel
authors.initials: E
authors.lastname: Barbosa-Stancioli
authors.affiliation: Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Moreno
authors.affiliation: Fundação Hemominas, Belo Horizonte, Minas Gerais, Brazil. Electronic address: annaproietti@gmail.com.
authors.forename: Anna Bárbara
authors.initials: AB
authors.lastname: Carneiro-Proietti
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001782:Blood Donors; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006526:Hepatitis C / Q000097:blood* / Q000453:epidemiology*; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D018937:Hepatitis C Antibodies
keywords: Blood donor; HCV antibodies; Hepatitis C virus; Prevalence