title: Eltrombopag Use in Thrombocytopenia for Endoscopic Submucosal Dissection of a Gastric Carcinoid.
abstract: Severe thrombocytopenia is a contraindication for therapeutic endoscopy due to the risk of bleeding. Platelet transfusions can temporarily increase platelet count, but are difficult to administer in the 2 weeks following endoscopic resection, during which the patient is at high risk for delayed bleeding. We present the use of a novel thrombopoietin receptor agonist, eltrombopag, to sustain platelet levels for the safe and complete endoscopic submucosal dissection of a gastric carcinoid in a patient with severe thrombocytopenia due to cirrhosis and idiopathic thrombocytopenic purpura. We performed complete and safe endoscopic removal of a gastric carcinoid after correcting the thrombocytopenia.
authors.affiliation: Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Kolb
authors.affiliation: Department of Medicine, Division of Gastroenterology, VA Palo Alto Health Care System, Palo Alto, CA.
authors.forename: Tonya
authors.initials: T
authors.lastname: Kaltenbach
authors.affiliation: Department of Medicine, Division of Hematology Oncology, VA Palo Alto Health Care System, Palo Alto, CA.
authors.forename: Beth
authors.initials: B
authors.lastname: Martin
authors.affiliation: Department of Pathology, VA Palo Alto Health Care System, Palo Alto, CA.
authors.forename: Robert V
authors.initials: RV
authors.lastname: Rouse
authors.affiliation: Department of Medicine, Division of Gastroenterology, VA Palo Alto Health Care System, Palo Alto, CA.
authors.forename: Roy
authors.initials: R
authors.lastname: Soetikno