title: [Trace Analysis of Lead in Copper Gluconate by Atomic Absorption Spectrometry after Separation by Co-Precipitation with Bismuth].
abstract: In order to determine trace amounts of lead in copper gluconate by atomic absorption spectrometry (AAS), the authors investigated a separation and pre-concentration procedure using a co-precipitation technique with bismuth. After ashing 2.0 g of the sample by means of a dry process, the ash was dissolved in (1→100) nitric acid and 75 μg of bismuth was added. Lead was co-precipitated by using an ammonium solution controlled to pH 9.5-10.5. The precipitate was left at room temperature for over 15 minutes to age, and then washed with a (3→100) ammonium solution three times. The precipitate was dissolved in (1→100) nitric acid and then analyzed by AAS. The quantification limit of this method was 0.5 mg/kg, and the trueness, repeatability and intermediate precision were 99.6%, 4.2% and 4.2% at the spiked concentration of 0.5 mg/kg, and 94.4%, 2.8% and 4.0% at the spiked concentration of 5.0 mg/kg, respectively. Thus, the present method for trace analysis of lead in copper gluconate was validated.
authors.affiliation: Japan Food Research Laboratories.
authors.forename: Michio
authors.initials: M
authors.lastname: Ito
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ishiguro
authors.forename: Fumihito
authors.initials: F
authors.lastname: Takahashi
authors.forename: Takakazu
authors.initials: T
authors.lastname: Nomura
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Sugimoto
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nishimura
mesh_terms: D064751:Ammonium Compounds; D001729:Bismuth; D002119:Calcium Carbonate; D011232:Chemical Precipitation; D002951:Citrates; D004338:Drug Combinations; D005503:Food Additives / Q000737:chemistry*; D005506:Food Contamination / Q000032:analysis*; D005942:Gluconates / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007854:Lead / Q000032:analysis*; D008277:Magnesium Oxide; D013054:Spectrophotometry, Atomic / Q000379:methods*; D013696:Temperature
chemical_list: D064751:Ammonium Compounds; D002951:Citrates; D004338:Drug Combinations; D005503:Food Additives; D005942:Gluconates; C050615:Suby's G solution; D007854:Lead; D008277:Magnesium Oxide; D002119:Calcium Carbonate; D001729:Bismuth