title: An Economic Evaluation of a Weight Loss Intervention Program for People with Serious Mental Illnesses Taking Antipsychotic Medications.
abstract: Individuals with serious mental illnesses suffer from obesity and cardiometabolic diseases at high rates, and antipsychotic medications exacerbate these conditions. While studies have shown weight loss and lifestyle interventions can be effective in this population, few have assessed intervention cost-effectiveness. We present results from a 12-month randomized controlled trial that reduced weight, fasting glucose, and medical hospitalizations in intervention participants. Costs per participant ranged from $4365 to $5687. Costs to reduce weight by one kilogram ranged from $1623 to $2114; costs to reduce fasting glucose by 1 mg/dL ranged from $467 to $608. Medical hospitalization costs were reduced by $137,500.
authors.affiliation: Kaiser Permanente Northwest, Center for Health Research, 3800 N. Interstate Avenue, Portland, OR, 97227, USA. Richard.Meenan@kpchr.org.
authors.forename: Richard T
authors.initials: RT
authors.lastname: Meenan
authors.affiliation: Kaiser Permanente Northwest, Center for Health Research, 3800 N. Interstate Avenue, Portland, OR, 97227, USA.
authors.forename: Scott P
authors.initials: SP
authors.lastname: Stumbo
authors.affiliation: Kaiser Permanente Northwest, Center for Health Research, 3800 N. Interstate Avenue, Portland, OR, 97227, USA.
authors.forename: Micah T
authors.initials: MT
authors.lastname: Yarborough
authors.affiliation: Kaiser Permanente Northwest, Center for Health Research, 3800 N. Interstate Avenue, Portland, OR, 97227, USA.
authors.forename: Michael C
authors.initials: MC
authors.lastname: Leo
authors.affiliation: Kaiser Permanente Northwest, Center for Health Research, 3800 N. Interstate Avenue, Portland, OR, 97227, USA.
authors.forename: Bobbi Jo H
authors.initials: BJ
authors.lastname: Yarborough
authors.affiliation: Kaiser Permanente Northwest, Center for Health Research, 3800 N. Interstate Avenue, Portland, OR, 97227, USA.
authors.forename: Carla A
authors.initials: CA
authors.lastname: Green
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects*; D001786:Blood Glucose / Q000378:metabolism; D031204:Caloric Restriction; D002318:Cardiovascular Diseases; D003362:Cost-Benefit Analysis; D004035:Diet Therapy; D015444:Exercise; D006760:Hospitalization / Q000191:economics; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D009765:Obesity / Q000139:chemically induced / Q000191:economics / Q000628:therapy*; D050177:Overweight / Q000139:chemically induced / Q000191:economics / Q000628:therapy; D040242:Risk Reduction Behavior; D014481:United States; D061217:Weight Reduction Programs / Q000191:economics / Q000379:methods*
chemical_list: D014150:Antipsychotic Agents; D001786:Blood Glucose
keywords: Behavioral intervention; Economic evaluation; Glucose control; Randomized controlled trial; Serious mental illness; Weight loss