title: The role of viral co-infection in HIV-associated non-AIDS-related cancers.
abstract: HIV-infected individuals are at increased risk for most types of cancer, including those typically classified as non-AIDS-defining cancers (NADCs). This increased risk is likely multifactorial, but a prominent risk factor for the increased rate of some cancers is co-infection with oncogenic viruses. Anal cancer, hepatocellular carcinoma, and Hodgkin lymphoma are three of the most common NADCs, and they are associated with co-infection with human papillomavirus, hepatitis B and C, and Epstein Barr virus, respectively. This review will examine the epidemiology, pathogenesis, and future trends around these virally associated NADCs frequently found in HIV-infected individuals.
authors.affiliation: Institute of Human Virology and Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, MD, USA, driedel@ihv.umaryland.edu.
authors.forename: David J
authors.initials: DJ
authors.lastname: Riedel
authors.forename: Lydia S
authors.initials: LS
authors.lastname: Tang
authors.forename: Anne F
authors.initials: AF
authors.lastname: Rositch
mesh_terms: D001005:Anus Neoplasms / Q000150:complications*; D006528:Carcinoma, Hepatocellular / Q000150:complications*; D060085:Coinfection; D015658:HIV Infections / Q000150:complications*; D019694:Hepatitis B, Chronic / Q000150:complications; D019698:Hepatitis C, Chronic / Q000150:complications; D006689:Hodgkin Disease / Q000150:complications*; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications*; D012307:Risk Factors