title: [Gastric ulcer, duodenal ulcer].
abstract: Recently, the acid secretion amount is increased by westernization of foods and Helicobacter pylori (H. pylori) infected patient's decrease in Japanese. Therefore, the recent tendencies are decrease of peptic ulcer diseases by H. pylori infection and increase of non-steroidal anti-inflammatory drugs(NSAIDs) ulcers. The endoscopic hemostasis should be performed for upper gastrointestinal bleeding from peptic ulcers in the first choice. A surgery or interventional radiology (IVR) should be performed in the unsuccessfulness of endoscopic hemostasis. H. pylori eradication therapy is effective for healing and prevention of recurrence from peptic ulcers. For prevention of recurrence of NSAIDs ulcers, therapy with proton pump inhibitor is effective.
authors.forename: Shigenaga
authors.initials: S
authors.lastname: Matsui
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kashida
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Asakuma
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Sakurai
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kudo
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D004381:Duodenal Ulcer / Q000209:etiology / Q000628:therapy*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D016481:Helicobacter Infections; D006801:Humans; D011379:Prognosis; D013276:Stomach Ulcer / Q000209:etiology / Q000628:therapy*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal