title: Association of Serum Fetuin-A Levels with Allograft Outcome in Renal Transplant Recipients.
abstract: OBJECTIVE
  To determine serum fetuin-A pattern after renal transplantation and its association with graft outcome.
  
  
  METHODS
  In 41 renal transplant recipients, serum pretransplant fetuin-A levels and serum fetuin-A concentrations on days 7 and 30 after transplantation were measured using the enzyme-linked immunosorbent as­say (ELISA) method. Also, the association between serum fetuin-A levels with clinical and laboratory parameters was evaluated.
  
  
  RESULTS
  A significant decrease in serum fetuin-A levels was noted in the first week after transplantation (P < .001). Subsequently, it started to increase and surpass pretransplant values during the first month (P < .001). Pretransplant fetuin-A levels did not differ among patients with different diethylenetriamine pentaacetic acid (DTPA) results. In addition, serum fetuin-A levels did not significantly correlate with metabolic parameters.
  
  
  CONCLUSIONS
  In this prospective study there was no increase in serum fetuin-A levels during the first month and pretransplant fetuin-A levels are not predictive for allograft outcome in renal transplant recipients.
authors.affiliation: Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Abdolrasoul
authors.initials: A
authors.lastname: Mehrsai
authors.affiliation: Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Pourmand
authors.affiliation: Department of Urology, Bouali Hospital, Islamic Azad University, Tehran Medical Branch, Tehran, Iran.
authors.forename: Hamed
authors.initials: H
authors.lastname: Azhdari Tehrani
authors.affiliation: Department of Urology, Bouali Hospital, Islamic Azad University, Tehran Medical Branch, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Keyhan
authors.affiliation: Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohamad Reza
authors.initials: MR
authors.lastname: Rahmati
authors.affiliation: Research Development Center, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Ayat
authors.initials: A
authors.lastname: Ahmadi
authors.affiliation: Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran. sanaz_dehghani2002@yahoo.com.
authors.forename: Sanaz
authors.initials: S
authors.lastname: Dehghani
authors.affiliation: Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Rahil
authors.initials: R
authors.lastname: Mashhadi
mesh_terms: D000328:Adult; D064591:Allografts; D015415:Biomarkers / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000097:blood*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D066027:Transplant Recipients; D060749:alpha-2-HS-Glycoprotein / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D060749:alpha-2-HS-Glycoprotein