title: Caustic Injury and Stricture of the Esophagus After Long-Term Phenytoin Use.
abstract: A 50-year-old man with a history of epilepsy controlled with phenytoin presented for evaluation of dysphagia. History revealed the patient was taking his phenytoin daily without water. Barium esophagram showed severe stricturing of the mid-esophagus. Upper endoscopy revealed diffuse gross mucosal abnormality with a thick stricture and occasional exudate. Biopsies were consistent with a drug-induced injury with lymphocytic infiltration and epithelial cell necrosis.
authors.affiliation: Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, FL.
authors.forename: Kirbylee K
authors.initials: KK
authors.lastname: Nelson
authors.affiliation: Department of Internal Medicine, Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL.
authors.forename: Steven B
authors.initials: SB
authors.lastname: Clayton
authors.affiliation: Department of Pathology and Cell Biology, University of South Florida Morsani College of Medicine, Tampa, FL.
authors.forename: Anne L
authors.initials: AL
authors.lastname: Champeaux
authors.affiliation: Department of Radiology, University of South Florida Morsani College of Medicine, Tampa, FL.
authors.forename: John C
authors.initials: JC
authors.lastname: Feldman
authors.affiliation: Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Joy McCann Culverhouse Center for Swallowing Disorders, University of South Florida Morsani College of Medicine, Tampa, FL.
authors.forename: Joel E
authors.initials: JE
authors.lastname: Richter