title: [Cases of Fournier's Gangrene in Kinki University].
abstract: The aim of our study was to identify risk factors that may influence outcomes for patients presenting with Fournier gangrene. Twelve patients hospitalized and treated between August 2007 and August 2013 were included in this study. Distinct features were noted after one or two weeks of hospitalization. We did not observe a significant correlation between death risk and the extent of necrosis in this patient set. However, the extent of necrosis tended to correlate with the duration of hospitalization in the survivors. We also compared the results of blood biochemical analyses between the surviving and non-surviving groups. A significant difference was noted in the levels of glucose (Glu) after two weeks. In the non-surviving group, Glu levels were increased. These findings suggest a relationship between glycemic control after the initiation of therapy and death. We also examined the results of blood biochemical analyses according to the duration of hospitalization. The lactate dehydrogenase (LDH) levels at admission and LDH levels after two weeks were significantly higher in the patients with a duration of hospitalization longer than the median duration of 61.5 days. These findings suggest a relationship between the duration of hospitalization and the extent of necrosis at diagnosis.
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Shingo
authors.initials: S
authors.lastname: Toyoda
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Minami
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Mamoru
authors.initials: M
authors.lastname: Hashimoto
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Saito
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Shimizu
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yamamoto
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Taiji
authors.initials: T
authors.lastname: Hayashi
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Tsuji
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nozawa
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yoshimura
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Tokumi
authors.initials: T
authors.lastname: Ishii
authors.affiliation: The Department of Urology, Kinki University Faculty of Medicine.
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Uemura
mesh_terms: D000328:Adult; D000368:Aged; D018934:Fournier Gangrene / Q000097:blood / Q000401:mortality; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012720:Severity of Illness Index
chemical_list: D007770:L-Lactate Dehydrogenase