title: Nanometer-thick hyaluronic acid self-assemblies with strong adhesive properties.
abstract: The adhesive characteristics of poly(allylamine hydrochloride) (PAH)/hyaluronic acid (HA) self-assemblies were investigated using contact adhesion testing. Poly(dimethylsiloxane) spheres and silicon wafers were coated with layer-by-layer (LbL) assemblies of PAH/HA. No increase in adhesion was observed when surfaces covered with dried LbL films were placed in contact. However, bringing the coated surfaces in contact while wet and separating them after drying resulted in an increase by a factor of 100 in the work of adhesion (from one to three bilayers). Herein we discuss the adhesion in PAH/HA and PAH/poly(acrylic acid) assemblies. PAH/HA assemblies have potential application as strong biomedical adhesives.
authors.affiliation: †Division of Fibre Technology, School of Chemical Science and Engineering, and §The Wallenberg Wood Science Centre, School of Chemical Science and Engineering, KTH Royal Institute of Technology, Stockholm, SE-100 44 Stockholm, Sweden.
authors.forename: Andrew
authors.initials: A
authors.lastname: Marais
authors.affiliation: †Division of Fibre Technology, School of Chemical Science and Engineering, and §The Wallenberg Wood Science Centre, School of Chemical Science and Engineering, KTH Royal Institute of Technology, Stockholm, SE-100 44 Stockholm, Sweden.
authors.forename: Samuel
authors.initials: S
authors.lastname: Pendergraph
authors.affiliation: †Division of Fibre Technology, School of Chemical Science and Engineering, and §The Wallenberg Wood Science Centre, School of Chemical Science and Engineering, KTH Royal Institute of Technology, Stockholm, SE-100 44 Stockholm, Sweden.
authors.forename: Lars
authors.initials: L
authors.lastname: Wågberg
mesh_terms: D000269:Adhesives / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D006820:Hyaluronic Acid / Q000737:chemistry*; D008422:Materials Testing; D049329:Nanostructures / Q000737:chemistry*; D011073:Polyamines / Q000737:chemistry; D013499:Surface Properties
chemical_list: D000269:Adhesives; D020099:Coated Materials, Biocompatible; D011073:Polyamines; D006820:Hyaluronic Acid
keywords: adhesion; hyaluronic acid; layer-by-layer; poly(dimethylsiloxane); self-assembly