title: Antiphospholipid syndrome, antiphospholipid antibodies and solid organ transplantation.
abstract: Antiphospholipid syndrome is considered a high risk factor for any kind of surgery. Considering that all solid organ transplants are critically dependent on the patency of vascular anastomosis, there is much concern about the consequences this pro-thrombotic condition may have on transplantation. Relatively little information is available in the literature assessing the real risk that antiphospholipid syndrome or the presence of antiphospholipid antibodies represent in solid organ transplantation. The aim of this article is to review the literature related to transplantation of solid organs in patients diagnosed with antiphospholipid syndrome or patients with positive antiphospholipid antibodies.
authors.affiliation: Internal Medicine Department, Hospital Son Llàtzer, Palma de Mallorca, Illes Balears, Spain juan.glzmr@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: González-Moreno
authors.affiliation: Autoimmune Diseases Unit, Internal Medicine Department, Hospital Clínico San Cecilio, Granada, Spain.
authors.forename: J L
authors.initials: JL
authors.lastname: Callejas-Rubio
authors.affiliation: Autoimmune Diseases Unit, Internal Medicine Department, Hospital Clínico San Cecilio, Granada, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Ríos-Fernández
authors.affiliation: Autoimmune Diseases Unit, Internal Medicine Department, Hospital Clínico San Cecilio, Granada, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Ortego-Centeno
mesh_terms: D017153:Antibodies, Anticardiolipin / Q000276:immunology; D017152:Antibodies, Antiphospholipid / Q000276:immunology*; D016736:Antiphospholipid Syndrome / Q000175:diagnosis* / Q000276:immunology / Q000601:surgery; D005260:Female; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000276:immunology; D008875:Middle Aged; D016377:Organ Transplantation; D012307:Risk Factors; D019851:Thrombophilia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D013927:Thrombosis / Q000276:immunology / Q000503:physiopathology; D014181:Transplantation Immunology; D016896:Treatment Outcome
chemical_list: D017153:Antibodies, Anticardiolipin; D017152:Antibodies, Antiphospholipid; D016682:Lupus Coagulation Inhibitor
keywords: Antiphospholipid syndrome; anticardiolipin antibodies; lupus anticoagulant; solid organ transplantation; thrombophilia