title: [Association between polymorphisms in the human dopamine D3 receptor gene and genetic susceptibility of essential tremor].
abstract: OBJECTIVE
  To study the association between polymorphisms in the human dopamine D3 receptor ( DRD3 ) gene and genetic susceptibility of essential tremor in different groups.
  
  
  METHODS
  The DRD3 gene polymorphism in ET and health control groups were analyzed with MscI restricted fragment length polymorphism ( RFLP). The results of PCR-RFLP were analyzed by using the statistical software.
  
  
  RESULTS
  No significant differences in alleles and allele frequency of MscI site at the DRD3 gene locus were observed between healthy control and different ET groups.
  
  
  CONCLUSIONS
  There is no association between polymorphisms MscI site at DRD3 and genetic susceptibility of ET.
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.forename: Zhong
authors.initials: Z
authors.lastname: Zhao
mesh_terms: D000483:Alleles; D016022:Case-Control Studies; D020329:Essential Tremor / Q000235:genetics*; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D017448:Receptors, Dopamine D2; D050637:Receptors, Dopamine D3 / Q000235:genetics*
chemical_list: D017448:Receptors, Dopamine D2; D050637:Receptors, Dopamine D3