title: [Ligneous conjunctivitis].
abstract: METHODS
  We report the case of a 3-year-old female patient with therapy refractive recurrent conjunctivitis and membrane formation of the upper eyelid. After surgical removal the histological examination showed an image compatible with ligneous conjunctivitis. A manifest serum plasminogen deficiency (22 %) supported the diagnosis.
  
  
  METHODS
  The treatment with corticosteroids, heparin-containing and fresh frozen plasma (FFP) eye drops, renewed surgical ablation with perioperative intravenous FFP administration and local cyclosporine A eye drops achieved a stable condition with low disease activity.
  
  
  CONCLUSIONS
  The combination of these therapy approaches has been performed here for the first time and has not been described in the literature so far.
authors.affiliation: Klinik für Ophthalmologie, UKSH, Campus Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland. maya.bauer@uksh.de.
authors.forename: M
authors.initials: M
authors.lastname: Bauer
authors.affiliation: Klinik für Ophthalmologie, UKSH, Campus Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Koinzer
authors.affiliation: Institut für Pathologie, UKSH, Campus Kiel, Kiel, Deutschland.
authors.forename: I
authors.initials: I
authors.lastname: Oschlies
authors.affiliation: Klinik für Allgemeine Pädiatrie, UKSH Campus Kiel, Kiel, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Claviez
authors.affiliation: UKSH, Campus Kiel, Apotheke des Universitätsklinikums Schleswig-Holstein, Kiel, Deutschland.
authors.forename: K
authors.initials: K
authors.lastname: Tiede
authors.affiliation: Klinik für Ophthalmologie, UKSH, Campus Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Roider
authors.affiliation: Klinik für Ophthalmologie, UKSH, Campus Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Nölle
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000379:methods; D003231:Conjunctivitis; D016572:Cyclosporine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D010949:Plasma; D010951:Plasma Exchange / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D009883:Ophthalmic Solutions; D016572:Cyclosporine
keywords: Cyclosporine A; Fibrin; Fresh frozen plasma; Granulation tissue; Plasminogen