title: The outcome of pregnancy with new onset proteinuria without hypertension: retrospective observational study.
abstract: OBJECTIVE
  The aim of this study was to evaluate preeclampsia progression of isolated proteinuria and associations with pregnancy outcome.
  
  
  METHODS
  We performed a retrospective analysis in patients who were hospitalized for evaluation of new onset proteinuria without hypertension after 20 weeks of gestation between January 2012 and January 2014. One hundred fifty-seven patients who met the inclusion criteria were enrolled the study.
  
  
  RESULTS
  After detection of new onset proteinuria, 53 of 157 (33.7%) patients developed preeclampsia and the incidence of gestational proteinuria was found to be 0.33%. Twenty-four hours urine proteinuria testing results were significantly higher in preeclampsia (PE) group compared with the gestational proteinuria (GP) group (p < 0.01). Patients who developed preeclampsia delivered significantly earlier than the GP group (p < 0.01). The weights of the infants born to mothers in the PE group were significantly lower than the other group (p < 0.01).
  
  
  CONCLUSIONS
  The incidence of gestational proteinuria was lower than the previous studies. Preeclampsia developed in 33% of patients with new onset proteinuria in pregnancy. In patients who developed PE had significantly higher proteinuria, lower delivery time and birth weight in their infants. Therefore, patients with new onset proteinuria should be followed-up for preeclampsia development and associated morbidities.
authors.affiliation: a Department of Obstetrics and Gynaecology, Maternal-Fetal Medicine Unit , Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey and.
authors.forename: Ali
authors.initials: A
authors.lastname: Ekiz
authors.affiliation: a Department of Obstetrics and Gynaecology, Maternal-Fetal Medicine Unit , Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey and.
authors.forename: Basak
authors.initials: B
authors.lastname: Kaya
authors.affiliation: a Department of Obstetrics and Gynaecology, Maternal-Fetal Medicine Unit , Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey and.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Polat
authors.affiliation: a Department of Obstetrics and Gynaecology, Maternal-Fetal Medicine Unit , Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey and.
authors.forename: Muhittin Eftal
authors.initials: ME
authors.lastname: Avci
authors.affiliation: b Department of Obstetrics and Gynaecology , Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Ozkose
authors.affiliation: b Department of Obstetrics and Gynaecology , Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey.
authors.forename: Raziye
authors.initials: R
authors.lastname: Kicik Caliskan
authors.affiliation: a Department of Obstetrics and Gynaecology, Maternal-Fetal Medicine Unit , Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey and.
authors.forename: Gokhan
authors.initials: G
authors.lastname: Yildirim
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000209:etiology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011507:Proteinuria / Q000150:complications*; D012189:Retrospective Studies; D055815:Young Adult
keywords: Gestational proteinuria; perinatal outcome; preeclampsia