title: Hepatosplenic Cat-Scratch Disease in Children and the Positive Contribution of 18F-FDG Imaging.
abstract: Two patients were referred to our hospital because of suspected malignancy. In patient 1, a 4-year-old boy, a F-FDG PET scan showed an enlarged liver with multiple FDG-positive nodular lesions. In patient 2, a 16-year-old boy, a FDG PET-(low-dose) CT showed an enlarged liver and spleen with multiple nodular lesions and a solitary hypodense nodule adjacent to the pancreatic head. The lesions were thought to originate from infectious disease or lymphoma. Polymeric chain reaction (PCR) on a liver biopsy was positive for Bartonella henselae. Both patients were treated with antibiotics and recovered completely.
authors.affiliation: From the *Beatrix Children's Hospital, University Medical Centre Groningen; †Martini Hospital Groningen; and ‡Department of Nuclear Medicine and Molecular Imaging, University Medical Centre Groningen, Groningen, The Netherlands.
authors.forename: Karianne E
authors.initials: KE
authors.lastname: Kraft
authors.forename: Rienus A
authors.initials: RA
authors.lastname: Doedens
authors.forename: Riemer H J A
authors.initials: RH
authors.lastname: Slart
mesh_terms: D000293:Adolescent; D002372:Cat-Scratch Disease / Q000000981:diagnostic imaging*; D002675:Child, Preschool; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008107:Liver Diseases / Q000000981:diagnostic imaging*; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013158:Splenic Diseases / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18