title: Detection methods for centrifugal microfluidic platforms.
abstract: Centrifugal microfluidics has attracted much interest from academia as well as industry, since it potentially offers solutions for affordable, user-friendly and portable biosensing. A wide range of so-called fluidic unit operations, e.g. mixing, metering, liquid routing, and particle separation, have been developed and allow automation and integration of complex assay protocols in lab-on-a-disc systems. Besides liquid handling, the detection strategy for reading out the assay is crucial for developing a fully integrated system. In this review, we focus on biosensors and readout methods for the centrifugal microfluidics platform and cover optical as well as mechanical and electrical detection principles.
authors.affiliation: Department of Micro- and Nanotechnology, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.
authors.forename: Robert
authors.initials: R
authors.lastname: Burger
authors.affiliation: Department of Micro- and Nanotechnology, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.
authors.forename: Letizia
authors.initials: L
authors.lastname: Amato
authors.affiliation: Department of Micro- and Nanotechnology, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.
authors.forename: Anja
authors.initials: A
authors.lastname: Boisen
mesh_terms: D001331:Automation; D015374:Biosensing Techniques / Q000379:methods*; D002498:Centrifugation / Q000379:methods; D004867:Equipment Design; D046210:Microfluidic Analytical Techniques / Q000379:methods*; D055096:Optical Devices