title: Recurrent nonconvulsive status epilepticus in a patient with progressive left hemispheric leukoencephalopathy after a remote viral meningoencephalitis.
abstract: Nonconvulsive status epilepticus (NCSE), defined as changes in behavior and/or mental processes from baseline with continuous epileptiform discharges, remains a diagnostic and treatment challenge. Here, we present a 68-year-old female who developed 3 episodes of NCSE 10 years after a viral meningoencephalitis which gradually progressed to left hemispheric leukoencephalopathy. In this case, we hypothesize that immune-mediated mechanisms and perhaps genetic predisposition played a role in epileptogenesis, and these will be discussed. This article is part of a Special Issue entitled "Status Epilepticus".
authors.affiliation: Department of Neurology, MacKay Memorial Hospital, No. 92, Sec 2, Zhong-shan North Road, Taipei 104, Taiwan. Electronic address: yjl5824@gmail.com.
authors.forename: Ya-Ju
authors.initials: YJ
authors.lastname: Lin
authors.affiliation: Department of Neurology, National Cheng Kung University Hospital Dou-Liou Branch, No. 345, Jhuangjing Road, Dou-Liou City, Yun-Lin County 640, Taiwan. Electronic address: chieningster@googlemail.com.
authors.forename: Chiening
authors.initials: C
authors.lastname: Lo
authors.affiliation: Department of Radiology, MacKay Memorial Hospital, No. 92, Sec 2, Zhong-shan North Road, Taipei 104, Taiwan. Electronic address: shojencheng@gmail.com.
authors.forename: Sho-Jen
authors.initials: SJ
authors.lastname: Cheng
authors.affiliation: Department of Neurology, MacKay Memorial Hospital, No. 92, Sec 2, Zhong-shan North Road, Taipei 104, Taiwan. Electronic address: cougarccl@hotmail.com.
authors.forename: Chao-Liang
authors.initials: CL
authors.lastname: Chou
authors.affiliation: Department of Neurology, MacKay Memorial Hospital, No. 92, Sec 2, Zhong-shan North Road, Taipei 104, Taiwan. Electronic address: ivy@mmh.org.tw.
authors.forename: I-Hung
authors.initials: IH
authors.lastname: Hseuh
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D056784:Leukoencephalopathies / Q000150:complications* / Q000209:etiology; D008590:Meningoencephalitis / Q000150:complications*; D012008:Recurrence; D013226:Status Epilepticus / Q000209:etiology*; D013997:Time Factors
keywords: EEG; Epileptiform discharge; Leukoencephalopathy; MRI; Nonconvulsive status epilepticus (NCSE); Postencephalitic epilepsy