title: Psychopharmacological options for adult patients with anorexia nervosa.
abstract: The aim of this review was to summarize evidence from research on psychopharmacological options for adult patients with anorexia nervosa (AN). Database searches of MEDLINE and PsycINFO (from January 1966 to January 2014) were performed, and original articles published as full papers, brief reports, case reports, or case series were included. Forty-one papers were screened in detail, and salient characteristics of pharmacological options for AN were summarized for drug classes. The body of evidence for the efficacy of pharmacotherapy in AN was unsatisfactory, the quality of observations was questionable (eg, the majority were not blinded), and sample size was often small. More trials are needed, while considering that nonresponse and nonremission are typical of patients with AN.
authors.affiliation: Dipartimento di Medicina Clinica e Sperimentale,Section of Psychiatry,University of Pisa,Pisa,Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Miniati
authors.affiliation: Dipartimento di Medicina Clinica e Sperimentale,Section of Psychiatry,University of Pisa,Pisa,Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Mauri
authors.affiliation: Dipartimento di Medicina Clinica e Sperimentale,Section of Psychiatry,University of Pisa,Pisa,Italy.
authors.forename: Agnese
authors.initials: A
authors.lastname: Ciberti
authors.affiliation: Dipartimento di Medicina Clinica e Sperimentale,Section of Psychiatry,University of Pisa,Pisa,Italy.
authors.forename: Michela Giorgi
authors.initials: MG
authors.lastname: Mariani
authors.affiliation: Dipartimento di Medicina Clinica e Sperimentale,Section of Psychiatry,University of Pisa,Pisa,Italy.
authors.forename: Donatella
authors.initials: D
authors.lastname: Marazziti
authors.affiliation: Dipartimento di Medicina Clinica e Sperimentale,Section of Psychiatry,University of Pisa,Pisa,Italy.
authors.forename: Liliana
authors.initials: L
authors.lastname: Dell'Osso
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000188:drug therapy*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D006801:Humans
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents
keywords: Anorexia nervosa; antidepressants; antipsychotics; eating disorders; pharmacological treatment