title: Palladium/Copper-Cocatalyzed Oxidative Amidobrominations of Alkenes.
abstract: In the presence of LiBr, a palladium/copper combination catalyzes dehydrogenative amidobrominations of acrylates with NH-sulfoximines, leading to N-vinylated products by dual NH/CH coupling, followed by oxidative enamide bromination. Mechanistically, the domino process is proposed to involve palladium(II) species as key intermediates. First synthetic applications of the products have been demonstrated.
authors.affiliation: Institut für Organische Chemie, RWTH Aachen University, Landoltweg 1, 52074 Aachen (Germany).
authors.forename: Xiao Yun
authors.initials: XY
authors.lastname: Chen
authors.affiliation: Institut für Organische Chemie, RWTH Aachen University, Landoltweg 1, 52074 Aachen (Germany).
authors.forename: Rebekka Anna
authors.initials: RA
authors.lastname: Bohmann
authors.affiliation: Institut für Organische Chemie, RWTH Aachen University, Landoltweg 1, 52074 Aachen (Germany).
authors.forename: Long
authors.initials: L
authors.lastname: Wang
authors.affiliation: Institut für Organische Chemie, RWTH Aachen University, Landoltweg 1, 52074 Aachen (Germany).
authors.forename: Shunxi
authors.initials: S
authors.lastname: Dong
authors.affiliation: Institut für Organische Chemie, RWTH Aachen University, Landoltweg 1, 52074 Aachen (Germany).
authors.forename: Christoph
authors.initials: C
authors.lastname: Räuber
authors.affiliation: Institut für Organische Chemie, RWTH Aachen University, Landoltweg 1, 52074 Aachen (Germany). Carsten.Bolm@oc.RWTH-Aachen.de.
authors.forename: Carsten
authors.initials: C
authors.lastname: Bolm
keywords: C–C bond formation; C–N bond formation; copper cocatalysis; dehydrogenative amidobromination; palladium catalysis