title: Endoscopic Endonasal Extended Approaches for the Management of Large Pituitary Adenomas.
abstract: The management of giant and large pituitary adenomas with wide intracranial extension or infrasellar involvement of nasal and paranasal cavities is a big challenge for neurosurgeons and the best surgical approach indications are still controversial. Endoscopic extended endonasal approaches have been proposed as a new surgical technique for the treatment of such selected pituitary adenomas. Surgical series coming from many centers all around the world are flourishing and results in terms of outcomes and complications seem encouraging. This technique could be considered a valid alternative to the transcranial route for the management of giant and large pituitary adenomas.
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Cappabianca
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy.
authors.forename: Luigi Maria
authors.initials: LM
authors.lastname: Cavallo
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy.
authors.forename: Oreste
authors.initials: O
authors.lastname: de Divitiis
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy.
authors.forename: Michelangelo
authors.initials: M
authors.lastname: de Angelis
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy.
authors.forename: Carmela
authors.initials: C
authors.lastname: Chiaramonte
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy. Electronic address: domenico.solari@unina.it.
authors.forename: Domenico
authors.initials: D
authors.lastname: Solari
mesh_terms: D000236:Adenoma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D009297:Nasal Mucosa / Q000601:surgery; D009300:Nasal Septum / Q000601:surgery; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods; D044583:Neuroendoscopy / Q000379:methods*; D009666:Nose; D010911:Pituitary Neoplasms / Q000473:pathology / Q000601:surgery*; D013524:Surgical Flaps; D047368:Tumor Burden
keywords: Endoscopic endonasal surgery; Extended approach; Giant adenoma; Pituitary adenoma; Transsphenoidal surgery