title: Trends in the incidence of pre-eclampsia and eclampsia in Taiwan between 1998 and 2010.
abstract: OBJECTIVE
  The aim of our study was to determine the relationship between age and the incidence of pre-eclampsia and eclampsia.
  
  
  METHODS
  We analyzed data collected by the National Health Insurance Bureau between 1998 and 2010. Data were obtained from the Taiwanese Department of Health website and the Department of Internal Affairs.
  
  
  RESULTS
  The incidence of pre-eclampsia increased significantly (from 0.87% to 1.21%), but the incidence of eclampsia did not change significantly (from 0.04% to 0.05%) between 1998 and 2010. The incidence of pre-eclampsia in the 20-24-year age group was 0.60 ± 0.09%. The relative risk of pre-eclampsia in the different age groups was as follows: aged <20 years, 1.02-fold (p = 1.0); 25-29 years, 1.35-fold (p = 0.041); 30-34 years, 1.79-fold (p < 0.001); 35-39 years, 2.99-fold (p < 0.001); and ≥40 years, 5.13-fold (p < 0.001). The incidence of eclampsia in the 20-24-year age group was 0.04 ± 0.01%. The incidence of eclampsia in only the ≥40-years age group significantly increased by 2.49-fold (p = 0.001).
  
  
  CONCLUSIONS
  The incidence of pre-eclampsia was correlated with maternal age. The incidence of pre-eclampsia was the lowest in the 20-24-year age group and soared in the >35-year age groups.
authors.affiliation: Department of Obstetrics and Gynecology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Te-Fu
authors.initials: TF
authors.lastname: Chan
authors.affiliation: Department of Public Health, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Yi-Ching
authors.initials: YC
authors.lastname: Tung
authors.affiliation: Department of Obstetrics and Gynecology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Shih-Han
authors.initials: SH
authors.lastname: Wang
authors.affiliation: Graduate Institute of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Chien-Hung
authors.initials: CH
authors.lastname: Lee
authors.affiliation: Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: chihlung1@yahoo.com.
authors.forename: Chih-Lung
authors.initials: CL
authors.lastname: Lin
authors.affiliation: Department of Medical Humanities and Education, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: peyilu@kmu.edu.tw.
authors.forename: Peih-Ying
authors.initials: PY
authors.lastname: Lu
mesh_terms: D000328:Adult; D004461:Eclampsia / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008423:Maternal Age; D011225:Pre-Eclampsia / Q000453:epidemiology*; D011247:Pregnancy; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult
keywords: Taiwan; age; eclampsia; pre-eclampsia