title: Memory-Associated Dynamic Regulation of the "Stable" Core of the Chromatin Particle.
abstract: Chromatin is a critical regulator of neural plasticity, but basic principles of chromatin function in neurons are unclear. In this issue of Neuron, Maze et al. (2015) establish histone H3.3 turnover as a novel mechanism contributing to CNS gene regulation, synaptic plasticity, and cognition.
authors.affiliation: Department of Psychology, University of Toronto Mississauga, Mississauga, ON L5L 1C6, Canada. Electronic address: iva.zovkic@utoronto.ca.
authors.forename: Iva B
authors.initials: IB
authors.lastname: Zovkic
authors.affiliation: Department of Neurobiology and Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL 35294-2182, USA. Electronic address: dsweatt@uab.edu.
authors.forename: J David
authors.initials: JD
authors.lastname: Sweatt
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D002843:Chromatin / Q000378:metabolism*; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006657:Histones / Q000378:metabolism*; D006801:Humans; D008297:Male; D009473:Neuronal Plasticity / Q000235:genetics*; D009474:Neurons / Q000378:metabolism*; D009707:Nucleosomes / Q000378:metabolism*
chemical_list: D002843:Chromatin; D006657:Histones; D009707:Nucleosomes