title: Intestinal Pseudo-Obstruction and Total Villous Atrophy of the Terminal Ileum: An Unusual Presentation of Untreated Celiac Disease.
abstract: Intestinal pseudo-obstruction (IPO) is a rare complication of celiac disease (CD) and has often resulted in laparotomy for diagnosis. We report an adult case of CD presenting as IPO with severe protein calorie malnutrition (PCM) and negative endomysial as well as tissue transglutaminase antibodies. This is the first case report of CD presenting with combined IPO, severe PCM, negative first-line celiac serologies, and terminal ileal atrophy that was diagnosed without laparotomy. A non-surgical diagnosis was achieved by expanded laboratory and endoscopic methods, including video capsule endoscopy. Extent of pathologic gut involvement and response to treatment with budesonide and gluten-free diet is described.
authors.affiliation: University of Illinois College of Medicine, Rockford, IL.
authors.forename: Eran C
authors.initials: EC
authors.lastname: Gwillim
authors.affiliation: University of Illinois College of Medicine, Rockford, IL ; Rockford Gastroenterology Associates, Rockford, IL.
authors.forename: Brad A
authors.initials: BA
authors.lastname: Bowyer