title: Synthesis of 2-Acylphenol and Flavene Derivatives from the Ruthenium-Catalyzed Oxidative C-H Acylation of Phenols with Aldehydes.
abstract: The cationic ruthenium hydride complex [(C6H6)(PCy3)(CO)RuH]+BF4-has been found to be an effective catalyst for the oxidative C-H coupling reaction of phenols with aldehydes to give 2-acylphenol compounds. The coupling of phenols with α,β-unsaturated aldehydes selectively gives the flavene derivatives. The catalytic method mediates direct oxidative C-H coupling of phenol and aldehyde substrates without using any metal oxidants or forming wasteful byproducts.
authors.affiliation: Department of Chemistry, Marquette University, Milwaukee, Wisconsin 53201-1881 USA, www.marquette.edu/chem/Yi.shtml.
authors.forename: Hanbin
authors.initials: H
authors.lastname: Lee
authors.affiliation: Department of Chemistry, Marquette University, Milwaukee, Wisconsin 53201-1881 USA, www.marquette.edu/chem/Yi.shtml.
authors.forename: Chae S
authors.initials: CS
authors.lastname: Yi
keywords: acylation; aldehyde; flavene; phenol; ruthenium