title: The Frequency of Enterobius Vermicularis Infections in Patients Diagnosed With Acute Appendicitis in Pakistan.
abstract: BACKGROUND
  The main aim of this study was to determine the frequency of Enterobius vermicularis infections and other unique histopathological findings in patients diagnosed with acute appendicitis.
  
  
  METHODS
  This retrospective study was conducted in a tertiary care hospital of Karachi, Pakistan over a time period of 9 years from 2005 to 2013. The recorded demographic and histopathological data for the 2956 appendectomies performed during this time frame were extracted using a structured template form. Negative and incidental appendectomies were excluded from the study.
  
  
  RESULTS
  Out of the 2956 patients diagnosed with acute appendicitis, 84 (2.8%) patients had Enterobius vermicularis infections. Malignancy (n=2, 0.1%) and infection with Ascaris (n=1, 0.1%) was found very rarely among the patients.Eggs in lumen (n=22, 0.7%), mucinous cystadenoma (n=28, 1.0%), mucocele (n=11, 0.4%), lymphoma (n=9, 0.3%), obstruction in lumen (n=17, 0.6%) and purulent exudate (n=37, 1.3%) were also seldom seen in the histopathological reports.
  
  
  CONCLUSIONS
  Enterobius vermicularis manifestation is a rare overall but a leading parasitic cause of appendicitis. Steps such as early diagnosis and regular de worming may help eradicate the need for surgeries.
authors.affiliation: Ziauddin University , Ziauddin Medical College, Karachi ,Pakistan. umer_ahmed_1@hotmail.com.
authors.forename: Muhammad Umer
authors.initials: MU
authors.lastname: Ahmed
authors.forename: Muhammad
authors.initials: M
authors.lastname: Bilal
authors.forename: Khurram
authors.initials: K
authors.lastname: Anis
authors.forename: Ali Mahmood
authors.initials: AM
authors.lastname: Khan
authors.forename: Kaneez
authors.initials: K
authors.lastname: Fatima
authors.forename: Iqbal
authors.initials: I
authors.lastname: Ahmed
authors.forename: Ali Mohammad
authors.initials: AM
authors.lastname: Khatri
authors.lastname: Shafiq-ur-Rehman
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000818:Animals; D001064:Appendicitis / Q000469:parasitology*; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D017229:Enterobiasis / Q000150:complications* / Q000453:epidemiology; D004757:Enterobius / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D055815:Young Adult