title: [Course and risk factors of maternal pregnancy-related anxiety across pregnancy in Ma' anshan city].
abstract: OBJECTIVE
  To explore the prevalence, trends and related influencing factors of pregnancy-related anxiety throughout pregnancy.
  
  
  METHODS
  A total of 990 pregnant women at the maternal and child health centers of Ma' anshan participated in all three surveys. Data on demographic characteristic and exposure factors during pregnancy were collected. The Pregnancy-related Anxiety Questionnaire was used to assess the anxiety symptoms. Generalized estimating equations (GEE) was used to evaluate the related influencing factors of pregnancy-related anxiety.
  
  
  RESULTS
  The mean score of the pregnancy-related anxiety were 20.3 ± 4.9, 19.6 ± 4.6, 18.9 ± 4.4 for the first, second and third trimester, respectively. Pregnancy-related anxiety showed a significant difference among the three trimesters ( F = 63.10, P < 0.001). Prevalence of pregnancy-related anxiety were 21.0%, 17.7% and 13.6%, respectively, at the first, second and third trimester. Results from GEE analysis indicated that maternal education of senior high school( OR = 1.36, 95% CI 1.05 - 1.75), lower family monthly income (OR =1.33, 95%, CI 1.01 - 1.75), unplanned pregnancy (OR = 2.60, 95% CI 2.05 - 3.29), history of miscarriage (OR = 1.30, 95% CI 1.06 - 1.60), vaginal bleeding (OR = 1.61, 95% CI 1.22 - 2.12), fever ( OR = 1.69, 95% CI 1.17 - 2.46) and use of nutritional supplementation during pregnancy ( OR = 1.43, 95% CI 1.08 - 1. 88 ) significantly increased the risk of pregnancy-related anxiety.
  
  
  CONCLUSIONS
  Pregnancy-related anxiety appeared a decrease from the first to third trimester. Maternal education, economic situation, unplanned pregnancy, history of miscarriage, and adverse physiological symptoms such as vaginal bleeding and fever were associated with the risk of pregnancy-related anxiety.
authors.forename: Xiuxiu
authors.initials: X
authors.lastname: Ding
authors.forename: Leijing
authors.initials: L
authors.lastname: Mao
authors.forename: Xing
authors.initials: X
authors.lastname: Ge
authors.forename: Shaojun
authors.initials: S
authors.lastname: Xu
authors.forename: Weijun
authors.initials: W
authors.lastname: Pan
authors.forename: Shuangqin
authors.initials: S
authors.lastname: Yan
authors.forename: Kun
authors.initials: K
authors.lastname: Huang
authors.forename: Fangbiao
authors.initials: F
authors.lastname: Tao
mesh_terms: D001007:Anxiety / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology / Q000523:psychology*; D011263:Pregnancy Trimester, Third; D015995:Prevalence; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires