title: Issues of sample size in sensitivity and specificity analysis with special reference to oncology.
abstract: Sample size is one of the basics issues, which medical researcher including oncologist faces with any research program. The current communication attempts to discuss the computation of sample size when sensitivity and specificity are being evaluated. The article intends to present the situation that the researcher could easily visualize for appropriate use of sample size techniques for sensitivity and specificity when any screening method for early detection of cancer is in question. Moreover, the researcher would be in a position to efficiently communicate with a statistician for sample size computation and most importantly applicability of the results under the conditions of the negotiated precision.
authors.affiliation: National Institute of Medical Statistics, ICMR, New Delhi, India.
authors.forename: Atul
authors.initials: A
authors.lastname: Juneja
authors.forename: Shashi
authors.initials: S
authors.lastname: Sharma
mesh_terms: D035843:Biomedical Research / Q000379:methods*; D006801:Humans; D008495:Medical Oncology / Q000379:methods*; D012107:Research Design; D018401:Sample Size; D012680:Sensitivity and Specificity