title: Monte Carlo-based dose calculation for (32)P patch source for superficial brachytherapy applications.
abstract: Skin cancer treatment involving (32)P source is an easy, less expensive method of treatment limited to small and superficial lesions of approximately 1 mm deep. Bhabha Atomic Research Centre (BARC) has indigenously developed (32)P nafion-based patch source (1 cm × 1 cm) for treating skin cancer. For this source, the values of dose per unit activity at different depths including dose profiles in water are calculated using the EGSnrc-based Monte Carlo code system. For an initial activity of 1 Bq distributed in 1 cm(2) surface area of the source, the calculated central axis depth dose values are 3.62 × 10(-10) GyBq(-1) and 8.41 × 10(-11) GyBq(-1)at 0.0125 and 1 mm depths in water, respectively. Hence, the treatment time calculated for delivering therapeutic dose of 30 Gy at 1 mm depth along the central axis of the source involving 37 MBq activity is about 2.7 hrs.
authors.affiliation: Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
authors.forename: Sridhar
authors.initials: S
authors.lastname: Sahoo
authors.affiliation: Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
authors.forename: Selvam T
authors.initials: ST
authors.lastname: Palani
authors.affiliation: Isotope Production and Applications Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Saxena
authors.affiliation: Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
authors.forename: D A R
authors.initials: DA
authors.lastname: Babu
authors.affiliation: Isotope Production and Applications Division, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India.
authors.forename: A
authors.initials: A
authors.lastname: Dash
keywords: 32P patch; brachytherapy; dosimetry; nafion; skin cancer