title: Palladium-catalyzed asymmetric intermolecular Mizoroki-Heck reaction for construction of a chiral quaternary carbon center.
abstract: Palladium-catalyzed asymmetric intermolecular Mizoroki-Heck reaction for the construction of a chiral quaternary carbon center is developed, affording 2,2-disubstituted 2,5-dihydrofurans in high yield with excellent enantioselectivity. The products are easily converted into the corresponding butenolides with retention of enantioselectivity.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China. dingch@sioc.ac.cn xlhou@sioc.ac.cn.
authors.forename: Qing-Song
authors.initials: QS
authors.lastname: Zhang
authors.forename: Shi-Li
authors.initials: SL
authors.lastname: Wan
authors.forename: Di
authors.initials: D
authors.lastname: Chen
authors.forename: Chang-Hua
authors.initials: CH
authors.lastname: Ding
authors.forename: Xue-Long
authors.initials: XL
authors.lastname: Hou
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D005663:Furans; D009942:Organometallic Compounds; D010165:Palladium; D002244:Carbon