title: Hydrogen Peroxide Scavenging Activity of Novel Coumarins Synthesized Using Different Approaches.
abstract: New derivatives of 7-hydroxy-4-methylcoumarin were synthesized using a chemical method and a microwave-assisted method to compare the feasibility, reaction times, and yields of the product. The newly synthesized coumarins were characterized by different spectroscopic techniques (FT-IR and NMR) and micro-elemental analysis (CHNS). In vitro antioxidant activities of these compounds were evaluated against hydrogen peroxide and were compared with standard natural antioxidant, vitamin C. Our results reveal that these compounds exhibit excellent radical scavenging activities.
authors.affiliation: Department of Chemical and Process Engineering, University Kebangsaan Malaysia (UKM), Bangi, Selangor, 43000, Malaysia; Environmental Research Center, University of Technology (UOT), Baghdad, 10001, Iraq.
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Al-Amiery
authors.affiliation: Environmental Research Center, University of Technology (UOT), Baghdad, 10001, Iraq.
authors.forename: Yasameen K
authors.initials: YK
authors.lastname: Al-Majedy
authors.affiliation: Environmental Research Center, University of Technology (UOT), Baghdad, 10001, Iraq.
authors.forename: Abdul Amir H
authors.initials: AA
authors.lastname: Kadhum
authors.affiliation: Environmental Research Center, University of Technology (UOT), Baghdad, 10001, Iraq; Fuel Cell Institute, University Kebangsaan Malaysia (UKM), Bangi, Selangor, 43000, Malaysia.
authors.forename: Abu Bakar
authors.initials: AB
authors.lastname: Mohamad
mesh_terms: D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000138:chemical synthesis* / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*
chemical_list: D003374:Coumarins; D016166:Free Radical Scavengers; D006861:Hydrogen Peroxide