title: Comparing social reciprocity in preserved speech variant and typical Rett syndrome during the early years of life.
abstract: This study compared early markers of social reciprocity in children with typical Rett syndrome (RTT) and in those with the preserved speech variant (PSV) of RTT. Retrospective video analysis of 10 toddlers with typical RTT and five with PSV investigated participants' orientation to their name being called between the ages of 5 and 24 months, prior to their diagnosis. From analysis of the recordings two distinct profiles were apparent. Although response rate was higher in girls with typical RTT than PSV at 5 to 8 months this noticeably reversed from 9 to 12 months onwards. By two years of age there was a markedly higher rate and range of responses from girls with PSV. This study contributes to the delineation of different profiles for the variants of RTT.
authors.affiliation: Rett Expertise Centre-GKC, Maastricht University Medical Centre, Maastricht, The Netherlands.
authors.forename: Gillian S
authors.initials: GS
authors.lastname: Townend
authors.affiliation: Institute of Physiology, Research Unit iDN - interdisciplinary Developmental Neuroscience, Center for Physiological Medicine, Medical University of Graz, Graz, Austria.
authors.forename: Katrin D
authors.initials: KD
authors.lastname: Bartl-Pokorny
authors.affiliation: School of Education, Victoria University of Wellington, Wellington, New Zealand.
authors.forename: Jeff
authors.initials: J
authors.lastname: Sigafoos
authors.affiliation: Rett Expertise Centre-GKC, Maastricht University Medical Centre, Maastricht, The Netherlands.
authors.forename: Leopold M G
authors.initials: LM
authors.lastname: Curfs
authors.affiliation: Center of Neurodevelopmental Disorders (KIND), Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Sven
authors.initials: S
authors.lastname: Bölte
authors.affiliation: Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany; Department of Child and Adolescent Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.
authors.forename: Luise
authors.initials: L
authors.lastname: Poustka
authors.affiliation: Institute of Physiology, Research Unit iDN - interdisciplinary Developmental Neuroscience, Center for Physiological Medicine, Medical University of Graz, Graz, Austria.
authors.forename: Christa
authors.initials: C
authors.lastname: Einspieler
authors.affiliation: Institute of Physiology, Research Unit iDN - interdisciplinary Developmental Neuroscience, Center for Physiological Medicine, Medical University of Graz, Graz, Austria; Center of Neurodevelopmental Disorders (KIND), Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden; BEE-PRI: Brain, Ears & Eyes-Pattern Recognition Initiative, BioTechMed-Graz, Graz, Austria. Electronic address: peter.marschik@medunigraz.at.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Marschik
mesh_terms: D002657:Child Development; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007398:Interpersonal Relations; D012189:Retrospective Studies; D015518:Rett Syndrome; D012919:Social Behavior; D014741:Video Recording
keywords: Family videos; Home videos; Preserved speech variant; Response to name; Retrospective video analysis; Rett syndrome; Social awareness