title: A Copper-Catalyzed Formal [3 + 2]-Cycloaddition for the Synthesis of All Different Aryl-Substituted Furans and Thiophenes.
abstract: A highly efficient formal [3 + 2]-cycloaddition was established using a copper catalyst. The resulting dihydrofurans were subjected to oxidation followed by arylations to produce tetraarylfurans. In addition, the dihydrofuran can be converted to diaryldihydrothiophene by using Lawesson's reagent. This protocol will facilitate the synthesis of all different aryl-substituted furans and thiophenes.
authors.affiliation: Graduate School of Science and Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube, Yamaguchi, 755-8611, Japan.
authors.forename: Shingo
authors.initials: S
authors.lastname: Ishikawa
authors.affiliation: Graduate School of Science and Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube, Yamaguchi, 755-8611, Japan.
authors.forename: Yushi
authors.initials: Y
authors.lastname: Noda
authors.affiliation: Graduate School of Science and Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube, Yamaguchi, 755-8611, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Wada
authors.affiliation: Graduate School of Science and Engineering, Yamaguchi University, 2-16-1 Tokiwadai, Ube, Yamaguchi, 755-8611, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishikata
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry; D061565:Cycloaddition Reaction; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D005663:Furans; D013876:Thiophenes; D003300:Copper