title: A case of Graham-Little-Piccardi-Lasseur syndrome.
abstract: Graham-Little-Piccardi-Lasseur Syndrome (GLPLS) is a variant of lichen planopilaris, which is characterized by progressive cicatricial alopecia of scalp, non-cicatricial alopecia of axillae and pubic regions, and keratosis pilaris-like follicular papules over trunk and extremities. GLPLS is a disease of unknown etiology. However, recent reports support a central role for a T-cell-mediated immune response in the pathogenesis of GLPLS. Besides, although GLPLS is believed to occur sporadically, a genetic predisposition also has been implicated in the pathogenesis. On the other hand, GLPLS typically affects middle-aged women, particularly of the postmenopausal age group. A diagnosis of GLPLS is generally apparent with the presence of characteristic findings in a postmenopausal woman. Herein, we report a case of GLPLS in a 75-year-old woman with the typical triad of alopecia of the scalp, non-cicatricial alopecia of axillae and pubis, and a follicular keratotic eruption on the trunk.
authors.affiliation: Ankara Numune Research and Training Hospital.
authors.forename: Ahu
authors.initials: A
authors.lastname: Yorulmaz
authors.forename: Ferda
authors.initials: F
authors.lastname: Artuz
authors.forename: Olcay
authors.initials: O
authors.lastname: Er
authors.forename: Servet
authors.initials: S
authors.lastname: Guresci
mesh_terms: D000368:Aged; D000505:Alopecia / Q000188:drug therapy / Q000473:pathology*; D001365:Axilla; D005260:Female; D006119:Groin; D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy / Q000473:pathology*; D012535:Scalp; D013577:Syndrome