title: Direct differentiation of herbal medicine for volatile components by a multicapillary column with ion mobility spectrometry method.
abstract: In this work, a headspace system coupled to a gas chromatographic column and ion mobility spectrometry was applied as a screening system to differentiate the crude and processed "atractylodis macrocephalae rhizoma" samples. The obtained ion mobility data were consecutively processed by principal component analysis and Radar fingerprint chart methods. From the principal component analysis for the initial solution to original variables, the two principal components accounted for 68 and 13% of the total variance, respectively. The established method was proven to be valuable for classification, discrimination between herbal medicines from different processing procedures.
authors.affiliation: Zhejiang Cancer hospital, Hangzhou, P.R. China.
authors.forename: Qinglin
authors.initials: Q
authors.lastname: Li
authors.affiliation: College of Basic Medical Science, Zhejiang Chinese Medical University, Hangzhou, P.R. China.
authors.forename: Rongqun
authors.initials: R
authors.lastname: Li
authors.affiliation: Research Center of TCM Processing Technology, Zhejiang Chinese Medical University, Hangzhou, P.R. China.
authors.forename: Gang
authors.initials: G
authors.lastname: Cao
authors.affiliation: Research Center of TCM Processing Technology, Zhejiang Chinese Medical University, Hangzhou, P.R. China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wu
authors.affiliation: School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P.R. China.
authors.forename: Guangming
authors.initials: G
authors.lastname: Yang
authors.affiliation: School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P.R. China.
authors.forename: Baochang
authors.initials: B
authors.lastname: Cai
authors.affiliation: Zhejiang Cancer hospital, Hangzhou, P.R. China.
authors.forename: Bin
authors.initials: B
authors.lastname: Cheng
authors.affiliation: Zhejiang Cancer hospital, Hangzhou, P.R. China.
authors.forename: Weimin
authors.initials: W
authors.lastname: Mao
keywords: Atractylodis macrocephalae rhizoma; Ion mobility spectrometry; Multicapillary column; Quality control