title: [News and perspectives in the treatment of advanced gastric and colorectal cancers].
abstract: Colorectal and gastric cancers are the fourth and third leading causes of cancer death world-wide. Unfortunately, gastric cancer is usually diagnosed at an advanced stage after becoming metastatic in distant sites, so that palliative therapy is the mainstay of treatment. Major progress in the understanding of the biology, the development of valid biomarkers and molecular targeted drugs have improved the treatment options and prognosis of both cancers significantly in the last years. Here, we review the current standards of care for patients with advanced and metastatic colorectal and gastric cancer and outline the perspectives for the future.
authors.forename: A
authors.initials: A
authors.lastname: Diciolla
authors.forename: V
authors.initials: V
authors.lastname: Cristina
authors.forename: R
authors.initials: R
authors.lastname: De Micheli
authors.forename: A
authors.initials: A
authors.lastname: Digklia
authors.forename: A D
authors.initials: AD
authors.lastname: Wagner
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000628:therapy*; D015179:Colorectal Neoplasms / Q000473:pathology / Q000628:therapy*; D018450:Disease Progression; D006801:Humans; D033183:Interdisciplinary Communication; D009362:Neoplasm Metastasis; D018579:Patient Selection; D013274:Stomach Neoplasms / Q000473:pathology / Q000628:therapy*; D035703:Therapies, Investigational / Q000639:trends*