title: [Effects of dietary wheat gluten level on decreasing plasma homocysteine concentration in rats].
abstract: OBJECTIVE
  To investigate the effects of different level of casein and wheat gluten on decreasing plasma homocysteine concentration in rats.
  
  
  METHODS
  48 rats of the Wistar were fed with different level of casein (12.5%, 25% and 50%) and wheat gluten (14.5%, 29% and 58%) diets for 14 days, and they were killed by decapitation to obtain blood and livers was subject to analysis the concentration of homocysteine, cysteine and other amino acids, as well as BHMT and CBS activities.
  
  
  RESULTS
  Body weight gain in rats fed wheat gluten dietary was significantly less than casein dietary, but food intake was significantly decreased in wheat gluten group with increasing of the protein content. The plasma homocysteine concentration in rats fed wheat gluten was marketly less than casein, however plasma cysteine concentration in wheat gluten was higher than casein group.
  
  
  CONCLUSIONS
  The effects of wheat gluten on plasma homocysteine concentration are mainly depends on the low contents of methionine and high cysteine content, but the low contents of lyscine and threonine are not ignored. The mainly mechanism is that the increased cysteine concentration promot enzyme activities of homocystein metabolism, and increase the consumption of homocysteine.
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Liu
authors.forename: Feng
authors.initials: F
authors.lastname: Han
authors.forename: Licui
authors.initials: L
authors.lastname: Sun
authors.forename: Jiaxi
authors.initials: J
authors.lastname: Lu
authors.forename: Kimio
authors.initials: K
authors.lastname: Sugiyama
authors.forename: Zhenwu
authors.initials: Z
authors.lastname: Huang
mesh_terms: D000596:Amino Acids; D000818:Animals; D002364:Caseins; D003545:Cysteine; D004032:Diet; D004044:Dietary Proteins; D005983:Glutens / Q000378:metabolism*; D006710:Homocysteine / Q000097:blood*; D008099:Liver; D008715:Methionine; D011506:Proteins; D051381:Rats; D017208:Rats, Wistar; D013912:Threonine; D014908:Triticum
chemical_list: D000596:Amino Acids; D002364:Caseins; D004044:Dietary Proteins; D011506:Proteins; D006710:Homocysteine; D013912:Threonine; D005983:Glutens; D008715:Methionine; D003545:Cysteine