title: Prosthetic valve thrombosis in a patient with mitral valve replacement.
abstract: Prosthetic valve thrombosis within one year after mitral valve replacement is rarely seen in patients on warfarin therapy and without any risk factor. Here, we describe a case of a 39-year- old female, who presented with dyspnoea and shortness of breath 11 months after mitral valve replacement. The echocardiogram revealed severe valvular stenosis due to presence of clots on the mitral valve and restricted motion of the mitral leaflets. As a result of deterioration of general condition and haemodynamic un-stability, plan was made to re-operate for her valve replacement surgery. This case report highlights the diagnosis, prevention and management of patients with prosthetic valve thrombosis following mitral valve replacement.
authors.affiliation: Medical Student, Dow University of Health Sciences, Karachi.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Bilal
authors.affiliation: Medical Student, Dow University of Health Sciences, Karachi.
authors.forename: Muhammad Shahzeb
authors.initials: MS
authors.lastname: Khan
authors.affiliation: House Officer, Civil Hospital, Karachi.
authors.forename: Abdul
authors.initials: A
authors.lastname: Haseeb
authors.affiliation: Cardiac Surgery, Civil Hospital, Karachi.
authors.forename: Abdul Bari
authors.initials: AB
authors.lastname: Khan
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D001705:Bioprosthesis; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000601:surgery; D012086:Reoperation; D012214:Rheumatic Heart Disease / Q000601:surgery; D013927:Thrombosis / Q000175:diagnosis / Q000517:prevention & control / Q000601:surgery*; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin
keywords: Prosthetic valve thrombosis; Mitral valve replacement.