title: Nontuberculous Mycobacterial Osteomyelitis in Human Immunodeficiency Virus-Negative Patients: A Case Series.
abstract: Nontuberculous mycobacterial bone infections among human immunodeficiency virus (HIV)-negative patients are rare, although a few studies have described such infections. We retrospectively reviewed the medical and microbiological data of HIV-negative osteomyelitis cases caused by nontuberculous mycobacteria treated in our tertiary-care hospital over 14 years from January 1, 2000, to December 31, 2013. Three HIV-negative patients had contracted bone infections due to nontuberculous mycobacteria. All of the patients had at least 1 predisposing condition that led to the infections: idiopathic CD4-positive lymphocytopenia and/or anti-interferon-γ autoantibody syndrome.
authors.affiliation: AIDS Clinical Center, National Center for Global Health and Medicine.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Eriko
authors.initials: E
authors.lastname: Morino
authors.forename: Jin
authors.initials: J
authors.lastname: Takasaki
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Nagahara
authors.forename: Haruhito
authors.initials: H
authors.lastname: Sugiyama
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D009164:Mycobacterium Infections / Q000453:epidemiology / Q000382:microbiology*; D009170:Nontuberculous Mycobacteria / Q000145:classification / Q000302:isolation & purification*; D010019:Osteomyelitis / Q000453:epidemiology / Q000382:microbiology*; D012189:Retrospective Studies; D012307:Risk Factors; D062606:Tertiary Care Centers