title: Prostatic adenocarcinoma presenting as isolated inguinal lymphadenopathy.
abstract: Prostatic adenocarcinoma (CaP) is the most common cancer in males and approximately 50% of patients have metastases at presentation, most commonly spreading to the bones and regional lymph nodes. CaP metastasising to inguinal lymph nodes in the absence of pelvic lymphadenopathy or other metastases is very uncommon. A 66-year-old man presented with isolated left inguinal lymphadenopathy of 3 months duration and a history of lower urinary tract symptoms for 1 year. He had prostatic cancer extending into the bladder base and seminal vesicles on contrast-enhanced CT of the pelvis, and asymptomatic vertebral secondaries on skeletal scintigraphy. Transrectal ultrasound biopsy revealed adenocarcinoma (Gleason score 3+4=7), and inguinal lymph node biopsy showed metastatic adenocarcinoma positive for prostate-specific antigen (PSA). As inguinal lymphadenopathy may also be due to other causes, biopsy is useful and meticulous clinical examination is a must in these patients.
authors.affiliation: Department of Urology, Institute of Nephro Urology, Bangalore, Karnataka, India.
authors.forename: Kanakaiah
authors.initials: K
authors.lastname: Doreswamy
authors.affiliation: Department of Urology, Institute of Nephro Urology, Pondicherry, India.
authors.forename: Vilvapathy Senguttuvan
authors.initials: VS
authors.lastname: Karthikeyan
authors.affiliation: Department of Urology, Institute of Nephro Urology, Bangalore, Karnataka, India.
authors.forename: Mahadevappa
authors.initials: M
authors.lastname: Nagabhushana
authors.affiliation: Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, India.
authors.forename: Bharatnur
authors.initials: B
authors.lastname: Shankaranand
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D000368:Aged; D000813:Anilides / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006801:Humans; D008206:Lymphatic Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D009570:Nitriles / Q000008:administration & dosage*; D009919:Orchiectomy; D017430:Prostate-Specific Antigen; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014105:Tosyl Compounds / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000813:Anilides; D000970:Antineoplastic Agents; D009570:Nitriles; D014105:Tosyl Compounds; C053541:bicalutamide; D017430:Prostate-Specific Antigen