title: Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis.
abstract: Psoriasis is a chronic inflammatory skin disease where the altered regulation in angiogenesis, inflammation, and proliferation of keratinocytes are the possible causes of the disease, and the transcription factor "hypoxia-inducible factor 1-alpha" (HIF-1α) is involved in the homeostasis of these three biological phenomena. In this review, the role of HIF-1α in the cross talk between the cytokines and cells of the immunological system involved in the pathogenesis of psoriasis is discussed.
authors.affiliation: Immunology Department, National School of Biological Sciences, National Polytechnic Institute, Plan de Ayala y Prolongación de Carpio S/N, Colonia Santo Tomás, Miguel Hidalgo, 11340 Mexico City, DF, Mexico.
authors.forename: Azael
authors.initials: A
authors.lastname: Torales-Cardeña
authors.affiliation: Immunology Department, National School of Biological Sciences, National Polytechnic Institute, Plan de Ayala y Prolongación de Carpio S/N, Colonia Santo Tomás, Miguel Hidalgo, 11340 Mexico City, DF, Mexico.
authors.forename: Isaí
authors.initials: I
authors.lastname: Martínez-Torres
authors.affiliation: Immunology Department, National School of Biological Sciences, National Polytechnic Institute, Plan de Ayala y Prolongación de Carpio S/N, Colonia Santo Tomás, Miguel Hidalgo, 11340 Mexico City, DF, Mexico.
authors.forename: Sandra
authors.initials: S
authors.lastname: Rodríguez-Martínez
authors.affiliation: Immunology Department, National School of Biological Sciences, National Polytechnic Institute, Plan de Ayala y Prolongación de Carpio S/N, Colonia Santo Tomás, Miguel Hidalgo, 11340 Mexico City, DF, Mexico.
authors.forename: Fernando
authors.initials: F
authors.lastname: Gómez-Chávez
authors.affiliation: Microbiology Department, National School of Biological Sciences, National Polytechnic Institute, Plan de Ayala y Prolongación de Carpio S/N, Colonia Santo Tomás, Miguel Hidalgo, 11340 Mexico City, DF, Mexico.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Cancino-Díaz
authors.affiliation: Immunology Department, National School of Biological Sciences, National Polytechnic Institute, Plan de Ayala y Prolongación de Carpio S/N, Colonia Santo Tomás, Miguel Hidalgo, 11340 Mexico City, DF, Mexico.
authors.forename: Ernesto A
authors.initials: EA
authors.lastname: Vázquez-Sánchez
authors.affiliation: Immunology Department, National School of Biological Sciences, National Polytechnic Institute, Plan de Ayala y Prolongación de Carpio S/N, Colonia Santo Tomás, Miguel Hidalgo, 11340 Mexico City, DF, Mexico.
authors.forename: Mario E
authors.initials: ME
authors.lastname: Cancino-Díaz
mesh_terms: D000818:Animals; D016764:Cell Polarity; D049109:Cell Proliferation; D016207:Cytokines / Q000502:physiology; D004195:Disease Models, Animal; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000502:physiology*; D007375:Interleukin-1 / Q000502:physiology; D051379:Mice; D018919:Neovascularization, Physiologic; D011565:Psoriasis / Q000209:etiology* / Q000276:immunology; D058504:Th17 Cells / Q000502:physiology; D042461:Vascular Endothelial Growth Factor A / Q000502:physiology
chemical_list: D016207:Cytokines; C497442:HIF1A protein, human; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D007375:Interleukin-1; D042461:Vascular Endothelial Growth Factor A; C572887:interleukin 36, human