title: Gold(I)-catalysed cascade reactions in the synthesis of 2,3-fused indole derivatives.
abstract: A gold(I)-catalysed hydroaminative/arylative cascade for the efficient synthesis of a variety of indole-fused skeletons has been developed. Factors controlling the catalyst loading required in these transformations involving 1,3-unsubstituted indole intermediates have been revealed, allowing isolation of an unprecedented 1,3-dimetallated 3H-indole gold complex characterized by X-ray diffraction.
authors.affiliation: Departamento de Química Orgánica, Universidad de Valencia, Avda. Vicent Andrés Estellés s/n 46100-Burjassot, Valencia, Spain. gregorio.asensio@uv.es.
authors.forename: Ana
authors.initials: A
authors.lastname: Gimeno
authors.forename: Alejandra
authors.initials: A
authors.lastname: Rodríguez-Gimeno
authors.forename: Ana B
authors.initials: AB
authors.lastname: Cuenca
authors.forename: Carmen
authors.initials: C
authors.lastname: Ramírez de Arellano
authors.forename: Mercedes
authors.initials: M
authors.lastname: Medio-Simón
authors.forename: Gregorio
authors.initials: G
authors.lastname: Asensio
mesh_terms: D002384:Catalysis; D006046:Gold / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D007211:Indoles; D006046:Gold