title: Clinical correlates of obsessive-compulsive symptom dimensions in at-risk mental states and psychotic disorders at early stages.
abstract: We studied the clinical correlates of obsessive-compulsive symptom dimensions in 109 individuals with early psychosis (31 At-Risk Mental States [ARMS], 78 psychotic disorders with <3 years of illness) and 59 healthy subjects. Obsessive-compulsive symptoms were assessed by the Obsessive-Compulsive Inventory - Revised. We also assessed the severity of psychotic symptoms, depressive symptoms and functioning. ARMS and psychotic disorder patients reported more obsessive-compulsive symptoms than did healthy subjects. The ARMS individuals also reported more overall and checking obsessive-compulsive symptoms compared with the PD patients. Different types of obsessive-compulsive symptoms were related with depressive symptoms in both diagnostic groups. However, a different pattern was observed in the relationship between obsessive-compulsive dimensions and functioning by diagnosis (better functioning in ARMS; poorer functioning in psychotic disorders). Our study suggests that obsessive-compulsive symptoms are present in the early stages of psychotic illness, as well as in individuals at risk for psychosis. Future prospective studies are needed to elucidate how obsessive-compulsive symptoms in ARMS may influence the prognosis in terms of global functioning and the risk of psychosis transition.
authors.affiliation: Early Intervention Service, Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: Mariné
authors.affiliation: Early Intervention Service, Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Creus
authors.affiliation: Early Intervention Service, Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
authors.forename: Montse
authors.initials: M
authors.lastname: Solé
authors.affiliation: Early Intervention Service, Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
authors.forename: Ángel
authors.initials: Á
authors.lastname: Cabezas
authors.affiliation: Early Intervention Service, Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Algora
authors.affiliation: Early Intervention Service, Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
authors.forename: Irene
authors.initials: I
authors.lastname: Moreno
authors.affiliation: Early Intervention Service, Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
authors.forename: Eduard
authors.initials: E
authors.lastname: Izquierdo
authors.affiliation: Early Intervention Service, Hospital Universitari Institut Pere Mata, IISPV, Universitat Rovira i Virgili, CIBERSAM, Reus, Spain.
authors.forename: Alexander
authors.initials: A
authors.lastname: Stojanovic-Pérez
authors.affiliation: Department of Psychiatry, Corporació Sanitària i Universitària Parc Taulí, C/Parc Taulí, 1, 08208 Sabadell, Barcelona, Spain. Electronic address: jlabad@tauli.cat.
authors.forename: Javier
authors.initials: J
authors.lastname: Labad
mesh_terms: D000293:Adolescent; D000328:Adult; D003192:Compulsive Behavior / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D011446:Prospective Studies; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D012307:Risk Factors; D055815:Young Adult
keywords: At-Risk Mental States; Depression; Functioning; Obsessive-compulsive disorder; Psychotic disorder