title: Neural Response Telemetry Thresholds in Patients with Cochlear Nerve Canal Stenosis.
abstract: OBJECTIVE
  To explore neural response telemetry (NRT) thresholds in patients with stenotic versus normal cochlear nerve canals.
  
  
  METHODS
  Case series with chart review.
  
  
  METHODS
  Tertiary referral center.
  
  
  METHODS
  Thirty pediatric patients with profound sensorineural hearing loss in at least 1 ear and no benefit from amplification underwent computed tomography imaging of the temporal bones. They were divided into 3 groups according to the diameter of the cochlear nerve canal: group A, <1.5 mm; group B, 1.5 to 1.7 mm; group C, 1.8 to 2.1 mm. All patients underwent cochlear implantation with full insertion of all electrodes. NRT was performed both intraoperatively and 6 months postoperatively in all patients; thresholds of electrodes 1, 11, and 22 were compared.
  
  
  RESULTS
  Per analysis of variance, intraoperative and 6-month postoperative NRT thresholds were both significantly different among groups A, B, and C at electrodes 1 and 22 but not at electrode 11. On intergroup analysis, group A showed statistically higher thresholds than those of groups B and C; however, no difference was found between groups B and C.
  
  
  CONCLUSIONS
  Cochlear nerve canal stenosis, defined as a canal diameter <1.5 mm, is associated with significantly increased NRT thresholds, which may play a role in postimplant performance.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Shuguang
authors.initials: S
authors.lastname: Han
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China wlebjyy@126.com.
authors.forename: Line
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Daoxing
authors.initials: D
authors.lastname: Zhang
authors.affiliation: Department of Head and Neck Surgery, David Geffen School of Medicine at the University of California, Los Angeles, California, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Peng
mesh_terms: D001309:Auditory Threshold / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation; D003056:Cochlear Nerve / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003251:Constriction, Pathologic; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery*; D006320:Hearing Tests; D006801:Humans; D007223:Infant; D008297:Male; D013686:Telemetry; D013701:Temporal Bone / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: cochlear implantation; cochlear nerve canal stenosis; cochlear nerve deficiency; neural response telemetry