title: A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria.
abstract: We report the design and synthesis of a red fluorescent AIE light-up probe for selective recognition, naked-eye detection, and image-guided photodynamic killing of Gram-positive bacteria, including vancomycin-resistant Enterococcus strains.
authors.affiliation: Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore 117576, Singapore. cheliub@nus.edu.sg.
authors.forename: Guangxue
authors.initials: G
authors.lastname: Feng
authors.forename: Youyong
authors.initials: Y
authors.lastname: Yuan
authors.forename: Hu
authors.initials: H
authors.lastname: Fang
authors.forename: Ruoyu
authors.initials: R
authors.lastname: Zhang
authors.forename: Bengang
authors.initials: B
authors.lastname: Xing
authors.forename: Guanxin
authors.initials: G
authors.lastname: Zhang
authors.forename: Deqing
authors.initials: D
authors.lastname: Zhang
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D005456:Fluorescent Dyes / Q000737:chemistry / Q000494:pharmacology / Q000528:radiation effects; D006094:Gram-Positive Bacteria / Q000187:drug effects* / Q000528:radiation effects* / Q000648:ultrastructure; D008027:Light; D018613:Microscopy, Confocal; D008855:Microscopy, Electron, Scanning; D055668:Photochemical Processes; D014640:Vancomycin / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D005456:Fluorescent Dyes; D014640:Vancomycin