title: Two new isoflavone 7-O-α-4″-anhydro-4″,5″-didehydroglucuronides from Streptomyces sp. LZ35ΔgdmAI.
abstract: Two isoflavone 7-O-α-4″-anhydro-4″,5″-didehydroglucuronides, namely daidzein 7-O-α-4″-anhydro-4″,5″-didehydroglucuronide (1) and genistein 7-O-α-4″-anhydro-4″,5″-didehydroglucuronide (2), were isolated and identified from the mutant strain of Streptomyces sp. LZ35ΔgdmAI. Their structures were elucidated by the analysis of their high resolution mass spectrometry (HR-MS) and 1D, 2D Nuclear magnetic Resonance (NMR) spectroscopic data. They are new natural products and maybe the transformed products of the soybean meal by Streptomyces sp. LZ35ΔgdmAI.
authors.affiliation: a Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University , No. 44 West Wenhua Road, Jinan , Shandong 250012 , P.R. China.
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Deng
authors.affiliation: a Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University , No. 44 West Wenhua Road, Jinan , Shandong 250012 , P.R. China.
authors.forename: Chun-Hua
authors.initials: CH
authors.lastname: Lu
mesh_terms: D002851:Chromatography, High Pressure Liquid; D019833:Genistein / Q000737:chemistry; D007529:Isoflavones / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D013025:Glycine max / Q000382:microbiology; D013302:Streptomyces / Q000737:chemistry* / Q000378:metabolism
chemical_list: D007529:Isoflavones; C000609509:daidzein 7-O-alpha-4''-anhydro-4'',5''-didehydroglucuronide; C000609510:genistein 7-O-alpha-4''-anhydro-4'',5''-didehydroglucuronide; C004742:daidzein; D019833:Genistein
keywords: Streptomyces sp. LZ35ΔgdmAI; biotransformation; isoflavone 7-O-α-4″-anhydro-4″,5″-didehydroglucuronide