title: A universal approach to ultrasmall magneto-fluorescent nanohybrids.
abstract: Seeded emulsion polymerization is a powerful universal method to produce ultrasmall multifunctional magnetic nanohybrids. In a two-step procedure, iron oxide nanocrystals were initially encapsulated in a polystyrene (PS) shell and subsequently used as beads for a controlled assembly of elongated quantum dots/quantum rods (QDQRs). The synthesis of a continuous PS shell allows the whole construct to be fixed and the composition of the nanohybrid to be tuned. The fluorescence of the QDQRs and magnetism of iron oxide were perfectly preserved, as confirmed by single-particle investigation, fluorescence decay measurements, and relaxometry. Bio-functionalization of the hybrids was straightforward, involving copolymerization of appropriate affinity ligands as shown by immunoblot analysis. Additionally, the universality of this method was shown by the embedment of a broad scale of NPs.
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Artur
authors.initials: A
authors.lastname: Feld
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Jan-Philip
authors.initials: JP
authors.lastname: Merkl
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Hauke
authors.initials: H
authors.lastname: Kloust
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Sandra
authors.initials: S
authors.lastname: Flessau
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Christian
authors.initials: C
authors.lastname: Schmidtke
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Christopher
authors.initials: C
authors.lastname: Wolter
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).|Center for Applied Nanotechnology, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Johannes
authors.initials: J
authors.lastname: Ostermann
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Michael
authors.initials: M
authors.lastname: Kampferbeck
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Robin
authors.initials: R
authors.lastname: Eggers
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany).|Center for Applied Nanotechnology, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Alf
authors.initials: A
authors.lastname: Mews
authors.affiliation: Center for Applied Nanotechnology, Grindelallee 117, 20146 Hamburg (Germany).
authors.forename: Theo
authors.initials: T
authors.lastname: Schotten
authors.affiliation: Institute of Physical Chemistry, University of Hamburg, Grindelallee 117, 20146 Hamburg (Germany). weller@chemie.uni-hamburg.de.|Center for Applied Nanotechnology, Grindelallee 117, 20146 Hamburg (Germany). weller@chemie.uni-hamburg.de.|The Hamburg Center for Ultrafast Imaging, University of Hamburg, Luruper Chaussee 149, 22761 Hamburg (Germany). weller@chemie.uni-hamburg.de.
authors.forename: Horst
authors.initials: H
authors.lastname: Weller
keywords: emulsion polymerization; magnetofluorescence; nanocomposites; nanohybrids; single-particle spectroscopy