title: Bilateral Lung Transplantation From a Donor With Heparin-Induced Thrombocytopenia.
abstract: We report the case of a 46-year-old male patient with a history of cystic fibrosis who received bilateral lung transplantation from a donor who died secondary to complications of heparin-induced thrombocytopenia. Postoperatively, he exhibited transient focal neurologic deficits and radiographic evidence of multiple cortical and subcortical infarctions. He was treated with a combination of fondaparinux and standard immunosuppressive therapy, made a full recovery, and experienced significantly improved lung function compared to pretransplantation capacity.
authors.affiliation: University of Virginia School of Medicine, Charlottesville, Virginia.
authors.forename: Joshua S
authors.initials: JS
authors.lastname: Jolissaint
authors.affiliation: Department of Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Mulloy
authors.affiliation: Department of Surgery, University of Virginia School of Medicine, Charlottesville, Virginia.
authors.forename: Julia C
authors.initials: JC
authors.lastname: Swanson
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
authors.forename: Dana P
authors.initials: DP
authors.lastname: Albon
authors.affiliation: Department of Surgery, University of Virginia School of Medicine, Charlottesville, Virginia. Electronic address: cll2y@virginia.edu.
authors.forename: Christine L
authors.initials: CL
authors.lastname: Lau
mesh_terms: D003550:Cystic Fibrosis / Q000601:surgery*; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D016040:Lung Transplantation / Q000379:methods; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000150:complications*; D014019:Tissue Donors
chemical_list: D006493:Heparin