title: Unilateral compressive optic neuropathy due to skull hyperostosis secondary to nutritional vitamin A deficiency.
abstract: We report a 17-year-old boy who presented with a chronic left unilateral optic neuropathy. Computerized tomography and magnetic resonance imaging demonstrated compression of the left optic nerve due to skull hyperostosis. He was found to be profoundly vitamin A deficient secondary to an unusual diet consisting predominantly of potato chips and crisps. Skull hyperostosis with cranial neuropathies and other neurological abnormalities has been described in growing animals fed vitamin A deficient diets but has not been previously reported in humans.
authors.affiliation: Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: Mohammed G
authors.initials: MG
authors.lastname: Zayed
authors.affiliation: Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Hickman
authors.affiliation: Department of Radiology, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: Ruth
authors.initials: R
authors.lastname: Batty
authors.affiliation: Metabolic Bone Centre, Sorby Wing, Northern General Hospital, Sheffield, UK.
authors.forename: Eugene V
authors.initials: EV
authors.lastname: McCloskey
authors.affiliation: Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: Irene M
authors.initials: IM
authors.lastname: Pepper
keywords: optic neuropathy; skull hyperostosis; vitamin A deficiency