title: Comparison of cord blood vitamin D levels in newborns of vitamin D supplemented and unsupplemented pregnant women: a prospective, comparative study.
abstract: OBJECTIVE
  To screen pregnant women for deficiency of 25-hydroxyvitamin D (25(OH)D) and supplement selected vitamin D deficient pregnant women with vitamin D and to compare 25(OH)D levels in cord blood between them.
  
  
  METHODS
  Sixty pregnant women were selected as cases (vitamin D levels <30 ng/ml) and 60 unscreened pregnant women were taken as controls. Cases were supplemented with available 60,000 IU vitamin D every two weeks for eight doses or till delivery, whichever was earlier. In both the cases and controls, cord blood was collected at the time of delivery and tested for 25(OH)D levels using Biomerieux miniVIDAS.
  
  
  RESULTS
  Maximum (66.7%) pregnant women who received vitamin D supplementation had cord blood vitamin D level >30 ng/ml, while only 3.3% unsupplemented pregnant women had cord blood vitamin D level >30 ng/ml. The median cord blood vitamin D level was 36.5 ng/ml in vitamin D supplemented and 11.35 ng/ml in unsupplemented women. The mean birth weight and mean crown heel length were 3.1 ± 0.485 kg versus 2.8 ± 0.705 kg and 49.35 ± 1.36 cm versus 48.67 ± 2.12 cm, respectively.
  
  
  CONCLUSIONS
  Vitamin D supplemented women had sufficient levels of 25(OH)D in cord blood at birth in maximum cases and neonates had higher birth weights and increased crown heel length.
authors.affiliation: a Department of Pediatrics , Artemis Health Institute , Gurgaon , Haryana , India .
authors.forename: Rajesh
authors.initials: R
authors.lastname: Nandal
authors.affiliation: a Department of Pediatrics , Artemis Health Institute , Gurgaon , Haryana , India .
authors.forename: Rajiv
authors.initials: R
authors.lastname: Chhabra
authors.affiliation: b Department of Neonatology , Fernandez Hospital , Hyderguda , Hyderabad , Andhra Pradesh , India .
authors.forename: Deepak
authors.initials: D
authors.lastname: Sharma
authors.affiliation: c Department of Obstetrics and Gynecology , SHKM Medical College Mewat , Haryana , India , and.
authors.forename: Meenakshi
authors.initials: M
authors.lastname: Lallar
authors.affiliation: d Department of Obstetrics and Gynecology , Artemis Health Institute , Gurgaon , Haryana , India.
authors.forename: Urvashi
authors.initials: U
authors.lastname: Rathee
authors.affiliation: a Department of Pediatrics , Artemis Health Institute , Gurgaon , Haryana , India .
authors.forename: Prabhat
authors.initials: P
authors.lastname: Maheshwari
mesh_terms: D000328:Adult; D019587:Dietary Supplements; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007231:Infant, Newborn; D008403:Mass Screening; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D039401:Prenatal Nutritional Physiological Phenomena; D011446:Prospective Studies; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood / Q000627:therapeutic use; D014808:Vitamin D Deficiency / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: 25(OD)D; Birth weight; cord blood; crown heel length; pregnancy; supplementation; vitamin D