title: Primary pericardial extragastrointestinal stromal tumor: A case report and literature review.
abstract: Gastrointestinal stromal tumors (GISTs) are the most prevalent mesenchymal tumors of the gastrointestinal tract. GISTs are considered to originate from the interstitial cells of Cajal, the pacemakers of the peristaltic activity of the gastrointestinal tract. More than 95% of GISTs express KIT protein and discovered on GIST-1. GISTs may also be encountered in locations outside the gastrointestinal tract, in which case they are referred to as extra-GISTs (EGISTs) and often behave more aggressively. This is the case report of a primary pericardial EGIST in a 53-year-old male patient, confirmed by immunohistochemistry. To the best of our knowledge, this is the third case of EGIST diagnosed above the diaphragm, without being associated with the esophageal wall. Two cases of primary EGIST arising from the pleura were reported previously. In addition, this is the first reported case of an EGIST originating from the pericardium.
authors.affiliation: Department of Radiology, Acibadem University, Acibadem Adana Hospital, Adana 01130, Turkey.
authors.forename: Taner
authors.initials: T
authors.lastname: Arpaci
authors.affiliation: Department of Pathology, Acibadem Maslak Hospital, Istanbul 34398, Turkey.
authors.forename: Fatma
authors.initials: F
authors.lastname: Tokat
authors.affiliation: Department of Pathology, Mersin University, Mersin 33000, Turkey.
authors.forename: Rabia Bozdogan
authors.initials: RB
authors.lastname: Arpaci
authors.affiliation: Department of Radiology, Acibadem University, Acibadem Adana Hospital, Adana 01130, Turkey.
authors.forename: Tugana
authors.initials: T
authors.lastname: Akbas
authors.affiliation: Department of Radiation Oncology, Acibadem University, Acibadem Adana Hospital, Adana 01130, Turkey.
authors.forename: Gamze
authors.initials: G
authors.lastname: Ugurluer
authors.affiliation: Department of Oncology, Acibadem University, Acibadem Adana Hospital, Adana 01130, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Yavuz
keywords: computed tomography; gastrointestinal stromal tumor; immunohistochemistry; pericardium