title: [Baseline characteristics and changes in treatment after a period of optimization of the patients included in the study EFICAR].
abstract: OBJECTIVE
  To describe the baseline date and drugs therapy changes during treatment optimization in patients with heart failure with depressed systolic function included in the EFICAR study.
  
  
  METHODS
  Multicenter randomized clinical trial.
  
  
  METHODS
  Seven Health Centers.
  
  
  METHODS
  150 patients (ICFSD) age 68±10 years, 77% male.
  
  
  METHODS
  Sociodemographic variables, comorbidities (Charlson index), functional capacity and quality of life. Drug therapy optimization was performed.
  
  
  RESULTS
  The main etiology was ischemic heart disease (45%), with 89% in functional class II. The Charlson index was 2.03±1.05. The ejection fraction mean was 37%±8, 19% with ejection fraction <30%. With the stress test 6.3±1.6 mean was reached, with the 6 minutes test 446±78 meters and the chair test 13.7±4.4 seconds. The overall quality of life with ejection fraction was 22.8±18.7 and with the Short Form-36 Health Survey, physical health 43.3±8.4 and mental health 50.1±10.6. After optimizing the treatment, the percentage of patients on drugs therapy and the dose of angiotensin converting enzyme inhibitors, angiotensin II receptor antagonists and beta-blockers were not changed.
  
  
  CONCLUSIONS
  The majority of the subjects are in functional class II, with functional capacity and quality of life decreased and comorbidity index high. A protocolized drug therapy adjustment did not increase the dose or number of patients with effective drugs for heart failure with depressed systolic function.
authors.affiliation: Instituto Investigación Biomédica Salamanca (IBSAL), Unidad Investigación de Atención Primaria, Centro de Salud Alamedilla, Servicio de Salud Castilla-León (SACYL), Salamanca, España; Departamento de Medicina, Universidad de Salamanca, Salamanca, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España. Electronic address: magomez@usal.es.
authors.forename: Manuel A
authors.initials: MA
authors.lastname: Gómez-Marcos
authors.affiliation: Instituto Investigación Biomédica Salamanca (IBSAL), Unidad Investigación de Atención Primaria, Centro de Salud Alamedilla, Servicio de Salud Castilla-León (SACYL), Salamanca, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
authors.forename: Cristina
authors.initials: C
authors.lastname: Agudo-Conde
authors.affiliation: Unidad Investigación, Atención Primaria Bizkaia, Servicio Vasco de Salud-Osakidetza (SVSO), Bizkaia, España; Centro Salud Basauri-Ariz, SVSO, Bizkaia, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
authors.forename: Jesús
authors.initials: J
authors.lastname: Torcal
authors.affiliation: Centro Salud de Galdakao, SVSO, Bizkaia, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
authors.forename: Pilar
authors.initials: P
authors.lastname: Echevarria
authors.affiliation: Centro Salud de Sant Roc, Servicio Catalán de Salud, Badalona, Barcelona, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
authors.forename: Mar
authors.initials: M
authors.lastname: Domingo
authors.affiliation: Centro Salud de Lutxana, SVSO, Bizkaia, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
authors.forename: María
authors.initials: M
authors.lastname: Arietaleanizbeascoa
authors.affiliation: Unidad Investigación, Atención Primaria Bizkaia, Servicio Vasco de Salud-Osakidetza (SVSO), Bizkaia, España.
authors.forename: Aitor
authors.initials: A
authors.lastname: Sanz-Guinea
authors.affiliation: Centro Salud Casa de Barco, SACYL, Valladolid, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
authors.forename: Maria M
authors.initials: MM
authors.lastname: de la Torre
authors.affiliation: Centro Salud Calviá, Servicio de Salud Balear, Mallorca, España; Centro Salud Casa de Barco, SACYL, Valladolid, España.
authors.forename: Jose I
authors.initials: JI
authors.lastname: Ramírez
authors.affiliation: Instituto Investigación Biomédica Salamanca (IBSAL), Unidad Investigación de Atención Primaria, Centro de Salud Alamedilla, Servicio de Salud Castilla-León (SACYL), Salamanca, España; Departamento de Medicina, Universidad de Salamanca, Salamanca, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
authors.forename: Luis
authors.initials: L
authors.lastname: García-Ortiz
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D015897:Comorbidity; D004359:Drug Therapy, Combination; D005260:Female; D006304:Health Status; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors
keywords: Atención primaria; Calidad de vida; Capacidad funcional; Functional capacity; Heart failure; Insuficiencia cardiaca; Primary care; Quality of life; Tratamiento; Treatment