title: Dielectric and FT-Raman spectroscopic approach to molecular identification of breast tumor tissues.
abstract: FT-Raman spectra and dielectric properties of benign and malignant women breast tissues in vitro were investigated. FT-Raman spectra for the malignant tissues showed a remarkably decrease in the lipid/protein ratio. Dielectric properties of women breast tissues measured in the low frequency range (42-10(6)Hz) were interpreted in spite of electrode polarization effect. Experimental results showed a contrast between the dielectric properties of malignant (Grade II) and benign tissues within the frequency range studied. The permittivity of malignant to normal breast tissue was found to be 160:1 while it could be 1.3:1 for fibrocystic breast tissues. These findings could contribute to distinguish between two breast tissues. The differences in spectral features between benign and malignant tissues may lead to breast cancer detection.
authors.affiliation: Spectroscopy Dep., National Research Centre, 33 EL Bohouth st. (former EL Tahrir st.), Dokki, P.O. 12622, Giza, Egypt.
authors.forename: Rasha
authors.initials: R
authors.lastname: Abd El-Hakam
authors.affiliation: Spectroscopy Dep., National Research Centre, 33 EL Bohouth st. (former EL Tahrir st.), Dokki, P.O. 12622, Giza, Egypt.
authors.forename: Safaa
authors.initials: S
authors.lastname: Khalil
authors.affiliation: Microwave Physics and Dielectrics Dep., National Research Centre, 33 EL Bohouth st. (former EL Tahrir st.), Dokki, P.O. 12622, Giza, Egypt. Electronic address: rmsoliman66@yahoo.com.
authors.forename: Ragab
authors.initials: R
authors.lastname: Mahani
mesh_terms: D000328:Adult; D000368:Aged; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis*; D017097:Electric Impedance; D005260:Female; D006801:Humans; D008875:Middle Aged; D013059:Spectrum Analysis, Raman / Q000379:methods*; D055815:Young Adult
keywords: Breast cancer; Dielectric spectroscopy; FT-Raman; Permittivity