title: Radiographic outcomes following treatment of intrabony defects by freeze-dried bone allograft combined with enamel matrix derivative: A retrospective study.
abstract: OBJECTIVE
  The aim of this study was to evaluate the radiographic outcomes following regenerative surgery using enamel matrix derivative (EMD) + freeze-dried bone allograft (FDBA).
  
  
  METHODS
  In total, 74 two- or three-wall intrabony defects were treated by a combination of EMD+FDBA followed by supportive periodontal therapy (SPT) for a minimum of 2 years. Radiographs were taken at baseline and after the follow-up period. The measurements taken were: baseline defect angle, CEJ to the coronal part of the alveolar bone crest (CEJ-BC), CEJ to the apical part of the intrabony defect (CEJ- BD), the intrabony component of the defect (DL), and the defect angle between the lines CEJ-BC and CEJ-BD.
  
  
  RESULTS
  Baseline defect angles were divided into three groups: first group defect angle ≤ 22 degrees; second group 22 degrees to 36 degrees; and third group ≥ 36 degrees. A significant difference in DL following treatment was found in all groups (6.930 mm, 4.202 mm, and 2.073 mm respectively; P < .01). The largest difference in DL was measured for the first group. A positive linear correlation was found between baseline values of the defect angle, CEJ-BD, CEJ-BC, and the later change in DL (P < .01).
  
  
  CONCLUSIONS
  The use of EMD+FDBA results in radiographic bone gain. Narrow defect angle and the depth of the intrabony component have significant positive correlation to radiographic bone gain.
authors.forename: Yelena
authors.initials: Y
authors.lastname: Tartakovsky
authors.forename: Ayana
authors.initials: A
authors.lastname: Goldstein
authors.forename: Moshe
authors.initials: M
authors.lastname: Goldstein
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D064591:Allografts; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging* / Q000601:surgery*; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D016025:Bone Transplantation / Q000379:methods*; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D005260:Female; D005612:Freeze Drying; D006801:Humans; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000628:therapy*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D003746:Dental Enamel Proteins