title: A 70-Year-Old Man With Large Cervical and Mediastinal Lymphadenopathies.
abstract: We present a case of a 70-year-old man with enlarged mediastinal and cervical lymph nodes that provided interesting radiologic and pathologic observations. The 70-year-old black man was found to have enlarged mediastinal lymph nodes. He had symptoms of atypical chest pain and generalized weakness for 2 weeks prior to the diagnosis. He denied shortness of breath, fever, chills, or night sweats. He was treated for hypertension and onychomycosis. Basic laboratory findings were within normal limits. Pulmonary function tests at the time of presentation showed FEV1, FVC, and FEV1/FVC ratio of 123% predicted, 133% predicted, and 0.7, respectively. Meanwhile, total lung capacity and carbon monoxide diffusing capacity were 103% and 107% predicted, respectively. Two weeks before he presented to our institution, the patient underwent bronchoscopy with transbronchial biopsies of the right lower lobe and endobronchial ultrasound-guided transbronchial needle aspiration of the right hilar lymph nodes.
authors.affiliation: Internal Medicine, Fairview Hospital, Cleveland Clinic, Cleveland, OH.
authors.forename: Shraddha
authors.initials: S
authors.lastname: Narechania
authors.affiliation: Department of Hematology and Oncology, Cleveland Clinic, Cleveland, OH.
authors.forename: Jason
authors.initials: J
authors.lastname: Valent
authors.affiliation: Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH.
authors.forename: Carol
authors.initials: C
authors.lastname: Farver
authors.affiliation: Department of Pulmonary, Allergy and Critical Care Medicine, Cleveland Clinic, Cleveland, OH; Respiratory Institute, Cleveland Clinic, Cleveland, OH. Electronic address: tonella@ccf.org.
authors.forename: Adriano R
authors.initials: AR
authors.lastname: Tonelli
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008477:Mediastinal Diseases / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*