title: Adult Xanthogranuloma, Reticulohistiocytosis, and Rosai-Dorfman Disease.
abstract: Adult xanthogranuloma presents most commonly as an orange-tan firm solitary nodule with no systemic manifestations. Recently, some cases have been reported in conjunction with lymphoproliferative disorders. Adult reticulohistiocytosis classically presents as red to yellow-red dermal nodules. In the multicentric form, lesions have a predilection for hands and elbows, with a classic coral bead periungual presentation, and are often associated with symmetric erosive arthritis, particularly of the hands and wrists. The presentation and course of Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy, can vary. The classic presentation is extensive, painless bilateral cervical lymphadenopathy, but some cases have been entirely extranodal.
authors.affiliation: Department of Dermatology, UCSF, 1701 Divisadero Street, San Francisco, CA 94115, USA.
authors.forename: Sarah S
authors.initials: SS
authors.lastname: Chisolm
authors.affiliation: Department of Dermatology, UCSF, 1701 Divisadero Street, San Francisco, CA 94115, USA; Department of Pathology, UCSF, 1701 Divisadero Street, San Francisco, CA 94115, USA.
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Schulman
authors.affiliation: Department of Dermatology, UCSF, 1701 Divisadero Street, San Francisco, CA 94115, USA. Electronic address: FoxLi@derm.ucsf.edu.
authors.forename: Lindy P
authors.initials: LP
authors.lastname: Fox
mesh_terms: D001327:Autoimmune Diseases / Q000453:epidemiology; D006099:Granuloma / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D015616:Histiocytosis, Non-Langerhans-Cell / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D015618:Histiocytosis, Sinus / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000453:epidemiology; D009369:Neoplasms / Q000453:epidemiology; D014973:Xanthomatosis / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy
keywords: Histiocytosis; Multicentric reticulohistiocytosis; Reticulohistiocytosis; Rosai-Dorfman disease; Self-healing reticulohistiocytosis; Xanthogranuloma