title: Does Postoperative Leukocyturia Influence Treatment Outcomes After Photoselective Vaporization of the Prostate (PVP)? A Prospective Short-Term Serial Follow-Up Study.
abstract: OBJECTIVE
  To identify serial changes in the incidence of leukocyturia after photoselective laser-vaporization of the prostate (PVP), to determine whether postoperative leukocyturia could be associated with surgical outcomes, and to identify predictors of persistent leukocyturia after PVP.
  
  
  METHODS
  A total of 102 men without leukocyturia on baseline urinalysis but underwent PVP were included in this prospective study. Treatment outcomes were assessed at 1 week, and 1, 3, 6, and 12 months postoperatively using International Prostate Symptom Score, Overactive Bladder Symptom Score (OABSS), uroflowmetry, postvoid residual, urinalysis, urine culture, and serum prostate-specific antigen (PSA).
  
  
  RESULTS
  The incidences of leukocyturia and dysuria at 1 week, and 1, 3, and 6 months postoperatively were 100.0%, 51.0%, 19.6%, and 0.0% and 30.3%, 25.4%, 5.9%, and 0.0%, respectively. Only one case of bacteriuria occurred throughout the entire follow-up period. At 1 month postoperatively, decrease in subtotal storage symptoms score, quality-of-life index, and total OABSS in patients without leukocyturia were significantly greater than in those with leukocyturia. At 3 months postoperatively, patients without leukocyturia showed greater improvement in subtotal storage symptoms score, total OABSS, quality-of-life index, bladder voiding efficiency, and postvoid residual compared with those with leukocyturia. On logistic regression analysis, age, PSA, prostate size, and amount of energy utilized were independent predictors of persistent leukocyturia 3 months after surgery.
  
  
  CONCLUSIONS
  Leukocyturia is observed in all patients immediately after PVP, but its incidence decreases with time. It may have adverse effects on treatment outcomes. Also, older age, higher serum PSA, larger prostate size, and greater amount of energy utilized may be risk factors of persistent leukocyturia.
authors.affiliation: Department of Urology, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Jung Kwon
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Department of Urology, Dongguk University College of Medicine, Goyang, Korea.
authors.forename: Jungbum
authors.initials: J
authors.lastname: Bae
authors.affiliation: Department of Urology, Dongguk University College of Medicine, Goyang, Korea.
authors.forename: Hae Won
authors.initials: HW
authors.lastname: Lee
authors.affiliation: Department of Urology, Dongguk University College of Medicine, Goyang, Korea.
authors.forename: Kwang Soo
authors.initials: KS
authors.lastname: Lee
authors.affiliation: Department of Urology, Dongguk University College of Medicine, Goyang, Korea. Electronic address: cmc1206@empal.com.
authors.forename: Min Chul
authors.initials: MC
authors.lastname: Cho
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*; D053844:Lasers, Solid-State / Q000009:adverse effects / Q000627:therapeutic use*; D007962:Leukocytes / Q000473:pathology*; D008297:Male; D011183:Postoperative Complications / Q000652:urine*; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D016482:Urinalysis; D014835:Volatilization