title: Tityus bahiensis scorpion venom injected to dams during pregnancy affects some cytokines of fetuses.
abstract: Due to the high incidence of scorpion stings in Brazil, pregnant women are among the possible victims. Cytokines are important during the pregnancy, and scorpion venoms can change their release. We evaluated the levels of some cytokines in the fetuses after the treatment of pregnant rats with the Tityus bahiensis scorpion venom. The concentration of some of them is altered and can be responsible for the effects previously observed on innate reflexes, and the physical and behavioral development of the offspring.
authors.affiliation: Laboratory of Pharmacology, Butantan Institute, São Paulo, Brazil; Post-Graduation Program of Disease Control Coordination of the Secretary of Public Health of the State of São Paulo, São Paulo, Brazil.
authors.forename: Ana L C
authors.initials: AL
authors.lastname: Dorce
authors.affiliation: Laboratory of Pharmacology, Butantan Institute, São Paulo, Brazil.
authors.forename: Eduardo O
authors.initials: EO
authors.lastname: Frare
authors.affiliation: Laboratory of Pharmacology, Butantan Institute, São Paulo, Brazil.
authors.forename: Maria E F V
authors.initials: ME
authors.lastname: Paulo
authors.affiliation: Laboratory of Pharmacology, Butantan Institute, São Paulo, Brazil.
authors.forename: Valquiria A C
authors.initials: VA
authors.lastname: Dorce
authors.affiliation: Laboratory of Pharmacology, Butantan Institute, São Paulo, Brazil. Electronic address: analeonor@butantan.gov.br.
authors.forename: Ana L A
authors.initials: AL
authors.lastname: Nencioni
mesh_terms: D000818:Animals; D001938:Brazil / Q000453:epidemiology; D016207:Cytokines / Q000097:blood*; D005260:Female; D005333:Fetus / Q000187:drug effects* / Q000378:metabolism; D015994:Incidence; D008297:Male; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D065008:Scorpion Stings / Q000453:epidemiology; D012604:Scorpion Venoms / Q000633:toxicity*; D012605:Scorpions / Q000378:metabolism*
chemical_list: D016207:Cytokines; D012604:Scorpion Venoms
keywords: Cytokines; Fetuses; Pregnancy; Scorpion venom; Tityus bahiensis