title: Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease.
abstract: BACKGROUND
  Despite growing literature on posterior vascular disease, specific information about the cognitive and functional profiles of patients with basilar artery occlusion disease (BAOD) is scarce. The aims of this study were (1) to compare the cognitive statuses of BAOD survivors versus healthy controls and (2) to correlate the functional capacity outcomes with the cognitive profiles of BAOD patients.
  
  
  METHODS
  Comprehensive cognitive and functional assessments were carried out in 28 patients with BAOD and 27 age- and education level-matched healthy controls.
  
  
  RESULTS
  Compared to matched controls, patients presented impairments in selective, sustained, and set-shifting attention, processing speed, visuospatial skills, mental flexibility, and monitoring rules. There were significant deficits in verbal episodic memory (immediate and delayed recall) and visuospatial episodic memory (immediate and delayed recall and recognition). Functional capacity outcomes were significantly related to the cognitive test results. Seventy-five percent of patients had a Modified Rankin Scale score of 0 or 1.
  
  
  CONCLUSIONS
  Our results indicate good functional outcomes in a selected group of BAOD survivors, despite the presence of subnormal performance on some cognitive tests, including tests of attention, executive function, and long-term memory.
authors.affiliation: Department of Neurology, University of São Paulo, 05403-000 São Paulo, SP, Brazil ; Stroke Clinic, Department of Neurology, University of São Paulo, 05403-000 São Paulo, SP, Brazil.
authors.forename: Kenia Repiso
authors.initials: KR
authors.lastname: Campanholo
authors.affiliation: Department of Neurology, University of São Paulo, 05403-000 São Paulo, SP, Brazil ; Stroke Clinic, Department of Neurology, University of São Paulo, 05403-000 São Paulo, SP, Brazil.
authors.forename: Adriana Bastos
authors.initials: AB
authors.lastname: Conforto
authors.affiliation: Department of Radiology, University of São Paulo, 05403-000 São Paulo, SP, Brazil.
authors.forename: Carolina Medeiros
authors.initials: CM
authors.lastname: Rimkus
authors.affiliation: Department of Neurology, University of São Paulo, 05403-000 São Paulo, SP, Brazil ; Stroke Clinic, Department of Neurology, University of São Paulo, 05403-000 São Paulo, SP, Brazil.
authors.forename: Eliane Correa
authors.initials: EC
authors.lastname: Miotto
mesh_terms: D000328:Adult; D000368:Aged; D001288:Attention / Q000502:physiology; D003072:Cognition Disorders / Q000209:etiology / Q000503:physiopathology*; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D012565:Schizophrenic Psychology; D020521:Stroke / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D014715:Vertebrobasilar Insufficiency / Q000150:complications* / Q000503:physiopathology / Q000523:psychology