title: Evaluation of the Effects of Dental Implants on Oral Lesions.
abstract: To determine whether dental implants impress oral lesions, and to evaluate the nature of their effect on the lesions.
  
  
  
  A comprehensive search was done via Google and PubMed for articles (including case reports and literature reviews) containing the keywords 'oral squamous cell carcinoma' (OSCC), 'oral lichen planus' (OLP), 'lichenoid contact reaction' (LCR), 'osseointegrated implants', and 'dental implants' , in the last 10 years (2002-2012).
  
  
  
  The study included 24 articles involving patients with dental implants, and some oral lesions (e.g. oral lichen planus and oral squamous cell carcinoma) or with a history of lesions. In these publications, there is evidence suggesting the possibility of emergence, exacerbation, recurrence, or even malignant transformation of the oral lesions after implant placement in some cases.
  
  
  
  Based on our review of the literature, implant treatment does not seem to be completely safe under any circumstances, but may have some complications in subjects with certain diseases (e.g. oral lesions, autoimmune diseases, malignancies, allergic reactions, etc.). Therefore prior to treatment, patients should be fully informed of the risks.
  
  
  
  Implant treatment is best done with caution in patients with cancer or mucocutaneous disorders.
authors.affiliation: Department of Oral and Maxillofacial Diseases, Faculty of Dentistry, Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Agha-Hosseini
authors.affiliation: Assistant Professor Department of Oral Medicine, AJA University of Medical Sciences, Tehran, Iran, Phone: 09127201069; Fax: +9821-88410770, e-mail: rohani_bita@ajaums.ac.ir.
authors.forename: Bita
authors.initials: B
authors.lastname: Rohani
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000503:physiopathology; D015921:Dental Implants / Q000009:adverse effects; D005882:Gingival Diseases / Q000503:physiopathology; D006801:Humans; D017676:Lichen Planus, Oral / Q000503:physiopathology; D017512:Lichenoid Eruptions / Q000503:physiopathology; D009059:Mouth Diseases / Q000503:physiopathology*; D009062:Mouth Neoplasms / Q000503:physiopathology
chemical_list: D015921:Dental Implants
keywords: Dental implant; Oral lichen planus; Oral squamous cell carcinoma.