title: [Prediction of spontaneous preterm birth in symptomatic patients: A review].
abstract: OBJECTIVE
  To identify predictors of preterm delivery in the context of threatened preterm labour.
  
  
  RESULTS
  Tobacco use and previous history of preterm delivery are the main anamnestic elements to predict preterm birth. High positive predictive value of vaginal examination is restricted to cases with strong cervical alterations like dilatation over 4 cm. In case of discrete cervical alterations, literature confirms the great interest for cervical length ultrasonographic measurement as it reduces false positive cases. Absence of fetal respiratory movements appears to be as sensitive as cervical length and could be more specific but its clinical use remains rare. Vaginal detection of fetal fibronectin is the most useful biomarker with high negative predictive value (>90%). Fibronectin quantitative test seems to enhance the positive predictive value. No other biomarker is currently used in clinical practice. Electromyography and elastography of the cervix appear to be promising approaches.
authors.affiliation: Pôle gynéco-obstétrique-reproduction humaine, CHU Estaing-Clermont-Ferrand, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France.
authors.forename: C
authors.initials: C
authors.lastname: Compan
authors.affiliation: Pôle gynéco-obstétrique-reproduction humaine, CHU Estaing-Clermont-Ferrand, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France.
authors.forename: A
authors.initials: A
authors.lastname: Rossi
authors.affiliation: Pôle gynéco-obstétrique-reproduction humaine, CHU Estaing-Clermont-Ferrand, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France.
authors.forename: G
authors.initials: G
authors.lastname: Piquier-Perret
authors.affiliation: Pôle gynéco-obstétrique-reproduction humaine, CHU Estaing-Clermont-Ferrand, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France; R2D2-EA7281, faculté de médecine, université d'Auvergne, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: A
authors.initials: A
authors.lastname: Delabaere
authors.affiliation: Pôle gynéco-obstétrique-reproduction humaine, CHU Estaing-Clermont-Ferrand, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France; EA4681, PEPRADE, faculté de médecine, université d'Auvergne, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: F
authors.initials: F
authors.lastname: Vendittelli
authors.affiliation: Pôle gynéco-obstétrique-reproduction humaine, CHU Estaing-Clermont-Ferrand, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France; EA4681, PEPRADE, faculté de médecine, université d'Auvergne, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: D
authors.initials: D
authors.lastname: Lemery
authors.affiliation: Pôle gynéco-obstétrique-reproduction humaine, CHU Estaing-Clermont-Ferrand, 1, place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand cedex 1, France; R2D2-EA7281, faculté de médecine, université d'Auvergne, place Henri-Dunant, 63000 Clermont-Ferrand, France. Electronic address: dgallot@chu-clermontferrand.fr.
authors.forename: D
authors.initials: D
authors.lastname: Gallot
mesh_terms: D002584:Cervix Uteri / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D005353:Fibronectins / Q000032:analysis*; D006801:Humans; D011247:Pregnancy; D047928:Premature Birth / Q000175:diagnosis*; D011296:Prenatal Diagnosis / Q000379:methods*; D014463:Ultrasonography
chemical_list: D005353:Fibronectins
keywords: Cervical length; Fetal fibronectin; Fibronectine fœtale; Longueur cervicale échographique; Menace d’accouchement prématuré; Prediction of preterm birth; Preterm birth; Prédiction de l’accouchement prématuré; Prématurité; Threatened preterm labour