title: Sleep-disordered breathing and future cardiovascular disease risk.
abstract: Sleep-disordered breathing occurs in 0.6-15% of reproductive age women. This condition is associated with an increased lifetime risk of cardiovascular disease, cardiovascular mortality, and all-cause mortality. A substantial body of evidence demonstrated increased perinatal morbidity among pregnancies affected by SDB including gestational diabetes, gestational hypertension, and preeclampsia. These same conditions are predictive of later cardiovascular disease. Treatment of SDB has been demonstrated to decrease future cardiovascular events and mortality. Screening at-risk individuals in the perinatal period can identify women with SDB, who can benefit from treatment. Continuous positive airway pressure and lifestyle interventions can decrease subsequent adverse cardiovascular health outcomes.
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, 2 Tampa General Circle, Suite 6055, Tampa, FL 33609.
authors.forename: Mary Ashley
authors.initials: MA
authors.lastname: Cain
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Women's Hospital/University of Pittsburgh Medical Center, Pittsburgh, PA.
authors.forename: Jason
authors.initials: J
authors.lastname: Ricciuti
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, 2 Tampa General Circle, Suite 6055, Tampa, FL 33609. Electronic address: jlouis1@health.usf.edu.
authors.forename: Judette M
authors.initials: JM
authors.lastname: Louis
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality / Q000517:prevention & control*; D015897:Comorbidity; D045422:Continuous Positive Airway Pressure; D037001:Directive Counseling / Q000379:methods*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D017286:Polysomnography; D012307:Risk Factors; D040242:Risk Reduction Behavior; D012891:Sleep Apnea Syndromes / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality; D014481:United States / Q000453:epidemiology
keywords: obesity; preeclampsia; sleep apnea; sleep disorderd breathing