title: Multi-walled Carbon Nanotubes/Graphite Nanosheets Modified Glassy Carbon Electrode for the Simultaneous Determination of Acetaminophen and Dopamine.
abstract: Graphite nanosheets prepared by thermal expansion and successive sonication were utilized for the construction of a multi-walled carbon nanotubes/graphite nanosheets based amperometric sensing platform to simultaneously determine acetaminophen and dopamine in the presence of ascorbic acid in physiological conditions. The synergistic effect of multi-walled carbon nanotubes and graphite nanosheets catalyzed the electrooxidation of acetaminophen and dopamine, leading to a remarkable potential difference up to 200 mV. The as-prepared modified electrode exhibited linear responses to acetaminophen and dopamine in the concentration ranges of 2.0 × 10(-6) - 2.4 × 10(-4) M (R = 0.999) and 2.0 × 10(-6) - 2.0 × 10(-4) M (R = 0.998), respectively. The detection limits were down to 2.3 × 10(-7) M for acetaminophen and 3.5 × 10(-7) M for dopamine (S/N = 3). Based on the simple preparation and prominent electrochemical properties, the obtained multi-walled carbon nanotubes/graphite nanosheets modified electrode would be a good candidate for the determination of acetaminophen and dopamine without the interference of ascorbic acid.
authors.affiliation: School of Materials Science and Engineering, Southwest University of Science and Technology, State Key Laboratory Cultivation Base for Nonmetal Composites and Functional Materials.
authors.forename: Susu
authors.initials: S
authors.lastname: Zhang
authors.forename: Ping
authors.initials: P
authors.lastname: He
authors.forename: Guangli
authors.initials: G
authors.lastname: Zhang
authors.forename: Wen
authors.initials: W
authors.lastname: Lei
authors.forename: Huichao
authors.initials: H
authors.lastname: He
mesh_terms: D000082:Acetaminophen / Q000032:analysis* / Q000737:chemistry*; D001205:Ascorbic Acid / Q000737:chemistry; D002384:Catalysis; D004298:Dopamine / Q000032:analysis* / Q000737:chemistry*; D004563:Electrochemistry / Q000295:instrumentation*; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D057230:Limit of Detection; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010084:Oxidation-Reduction; D015203:Reproducibility of Results; D013997:Time Factors
chemical_list: D037742:Nanotubes, Carbon; D000082:Acetaminophen; D006108:Graphite; D001205:Ascorbic Acid; D004298:Dopamine