title: [Update on therapy of chronic heart failure. Innovations and studies from last year].
abstract: Chronic heart failure is one of the most common chronic diseases worldwide with increasing prevalence and incidence. Due to the high morbidity and mortality a standardized and evidence-based therapy is crucial. The present review article gives an overview about the innovations in 2014 based on the current guidelines of the European Society of Cardiology. First, improvements in established medication regimens regarding beta blockers and mineralocorticoid receptor antagonists as well as treatment options for heart rate reduction will be explained. Second, new pharmacological developments, such as angiotensin receptor neprilysin inhibition will be discussed. Finally, new insights into common comorbidities of patients with chronic heart failure, such as atrial fibrillation and hyperkalemia will be presented.
authors.affiliation: Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Str., Geb. 40, 66421, Homburg/Saar, Deutschland. Sebastian.Ewen@uks.eu.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Ewen
authors.affiliation: Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Str., Geb. 40, 66421, Homburg/Saar, Deutschland.
authors.forename: Y
authors.initials: Y
authors.lastname: Linicus
authors.affiliation: Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Str., Geb. 40, 66421, Homburg/Saar, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Böhm
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage* / Q000592:standards; D002309:Cardiology / Q000592:standards*; D005060:Europe; D019317:Evidence-Based Medicine / Q000592:standards; D006333:Heart Failure / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans; D000451:Mineralocorticoid Receptor Antagonists / Q000008:administration & dosage*; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D000451:Mineralocorticoid Receptor Antagonists
keywords: Acute and chronic heart failure; Bendopnea; Comorbidity; European Society of Cardiology guidelines; Pharmacological therapy