title: Morphological study of Pipelle biopsy specimens in cases of abnormal uterine bleeding.
abstract: OBJECTIVE
  To determine the frequencies of common morphological patterns of abnormal uterine bleeding on Pipelle biopsy specimen.
  
  
  METHODS
  The cross-sectional study was conducted at PNS Shifa Hospital, Karachi, and comprised endometrial Pipelle biopsies of patients with abnormal uterine bleeding received between January 2013 and January 2014. Patient's age, marital status, parity and histopatholgical spectrum were recorded. SPSS 17 was used for data analysis.
  
  
  RESULTS
  Of the 101 patients, 53(52.50%) presented with proliferative endometrium, 22(21.80%) had secretory endometrium, 13(12.9%) presented with chronic non-specific endometritis, 8(7.9%) had endometrial hyperplasia without atypia, and 5(5%) had endometrial hyperplasia with atypia. Besides, 86(85.1 %) were nulliparous; 15(14.9%) were parous; 92(91.1%) were married and 9(8.9%) were unmarried.
  
  
  CONCLUSIONS
  The most common morphological pattern was proliferative endometrium. Though Pipelle has its own limitations, it performed better when endometrial pathology was global rather than focal.
authors.affiliation: Department of Histopathology, PNS-Shifa, DHA Phase II, Karachi.
authors.forename: Muhammad Tahir
authors.initials: MT
authors.lastname: Khadim
authors.affiliation: Department of Histopathology, PNS-Shifa, DHA Phase II, Karachi.
authors.forename: Talat
authors.initials: T
authors.lastname: Zehra
authors.affiliation: Department of Histopathology, PNS-Shifa, DHA Phase II, Karachi.
authors.forename: Hafiz Murtuza
authors.initials: HM
authors.lastname: Ashraf
mesh_terms: D000328:Adult; D001706:Biopsy / Q000295:instrumentation / Q000379:methods; D003430:Cross-Sectional Studies; D004714:Endometrial Hyperplasia / Q000150:complications / Q000473:pathology*; D004716:Endometritis / Q000150:complications / Q000473:pathology*; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D008796:Metrorrhagia / Q000209:etiology / Q000473:pathology*; D008875:Middle Aged; D010154:Pakistan; D010298:Parity; D055815:Young Adult
keywords: Endometrial pathology, Abnormal uterine bleeding, Pipelle endometrial biopsy.