title: Normothermic perfusion machine in liver transplant with cardiac death donor grafts.
abstract: The increasing difference between the number of patients in waiting lists for liver transplantation and the number of available donors has generated a great interest in the use of non-ideal organs, like grafts obtained from cardiac death donors (DCD). However, the extreme sensibility to ischemia of these livers results in a low utilization rate and a high percentage of post-transplant complications and re-transplantation. Normothermic perfusion machines (NMP) emerged as an alternative that tries to maintain the viability of the organ and even to improve its function. This review focuses on current results of DCD liver transplantation and on the role that NMP may have in this field.
authors.affiliation: Servicio de Cirugía Hepática y Trasplante Hepático, Hospital Clinic de Barcelona, España. Electronic address: mikepav2003@yahoo.com.
authors.forename: Mihai-Calin
authors.initials: MC
authors.lastname: Pavel
authors.affiliation: Servicio de Cirugía Hepática y Trasplante Hepático, Hospital Clinic de Barcelona, España.
authors.forename: Constantino
authors.initials: C
authors.lastname: Fondevila Campo
authors.affiliation: Servicio de Cirugía Hepática y Trasplante Hepático, Hospital Clinic de Barcelona, España.
authors.forename: David
authors.initials: D
authors.lastname: Calatayud Mizrahi
authors.affiliation: Servicio de Cirugía Hepática y Trasplante Hepático, Hospital Clinic de Barcelona, España.
authors.forename: Joana
authors.initials: J
authors.lastname: Ferrer Fabrega
authors.affiliation: Servicio de Cirugía Hepática y Trasplante Hepático, Hospital Clinic de Barcelona, España.
authors.forename: Santiago
authors.initials: S
authors.lastname: Sanchez Cabus
authors.affiliation: Servicio de Cirugía Hepática y Trasplante Hepático, Hospital Clinic de Barcelona, España.
authors.forename: Víctor
authors.initials: V
authors.lastname: Molina Santos
authors.affiliation: Servicio de Cirugía Hepática y Trasplante Hepático, Hospital Clinic de Barcelona, España.
authors.forename: Josep
authors.initials: J
authors.lastname: Fuster Obregon
authors.affiliation: Servicio de Cirugía Hepática y Trasplante Hepático, Hospital Clinic de Barcelona, España.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Garcia-Valdecasas Salgado
mesh_terms: D006323:Heart Arrest; D006801:Humans; D016031:Liver Transplantation; D010477:Perfusion / Q000295:instrumentation*; D013696:Temperature; D009927:Tissue and Organ Procurement / Q000379:methods*
keywords: Donación en asistolia; Donation after cardiac death; Isquemia caliente; Liver transplantation; Normothermic perfusion; Perfusión normotérmica; Trasplante hepático; Warm ischemia