title: The role of interleukin-32 against tuberculosis.
abstract: IL-32 is increasingly recognized to be an important host-protective molecule against tuberculosis. In this commentary, we highlight some of the potential mechanisms by which the immunomodulatory effect of IL-32 occurs against mycobacterial infections but also areas where mechanistic clarifications are needed.
authors.affiliation: Denver Veterans Affairs Medical Center, 1055 Clermont St, Denver, CO 80206, United States; Departments of Medicine and Academic Affairs, D509, Neustadt Building, National Jewish Health, 1400 Jackson St, Denver, CO 80206, United States; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver Anschutz Medical Campus, 12700 East 19th Avenue, Aurora, CO 80045-2539, United States.
authors.forename: Xiyuan
authors.initials: X
authors.lastname: Bai
authors.affiliation: Division of Infectious Diseases, University of Colorado Denver Anschutz Medical Campus, 12700 East 19th Avenue, Aurora, CO 80045-2539, United States.
authors.forename: Charles A
authors.initials: CA
authors.lastname: Dinarello
authors.affiliation: Denver Veterans Affairs Medical Center, 1055 Clermont St, Denver, CO 80206, United States; Departments of Medicine and Academic Affairs, D509, Neustadt Building, National Jewish Health, 1400 Jackson St, Denver, CO 80206, United States; Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver Anschutz Medical Campus, 12700 East 19th Avenue, Aurora, CO 80045-2539, United States. Electronic address: chane@njhealth.org.
authors.forename: Edward D
authors.initials: ED
authors.lastname: Chan
mesh_terms: D006801:Humans; D007378:Interleukins / Q000502:physiology*; D014376:Tuberculosis / Q000276:immunology / Q000503:physiopathology*
chemical_list: C496971:IL32 protein, human; D007378:Interleukins
keywords: Cytokine; Interleukin-32; Tuberculosis