title: Wear assessments of a new cervical spinal disk prosthesis: Influence of loading and kinematic patterns during in vitro wear simulation.
abstract: Surgical treatment is one of the effective methods of treatment in cervical spondylosis. The traditional method of operation is decompression fusion; however, this surgery results in restricted movement of cervical vertebra and adjacent segment degeneration. Due to the deficiency of traditional surgery, scholars have widely carried out artificial cervical disk replacement surgery and have achieved good clinical effects. Comparing to the characteristics of the common artificial cervical disk which is used frequently, we developed a new artificial cervical intervertebral disk prosthesis. The purpose of this study was to determine the wear behavior in a cervical total disk replacement system. The total disk replacement system tested consists of a ultra-high-molecular-weight polyethylene inlay articulating between a Ti6Al4V alloy superior plate and an inferior plate, using a spine wear simulator, per the ISO 18192-1:2011 standard test methods. Three rotations and axial force were applied on each station. The specimens were removed at 5 × 10(5) and 10(6) cycles and at intervals of 10(6) cycles thereafter to determine the actual mass loss. The serum was replaced every 5 × 10(5) cycles. The specimens were changed periodically among the different stations. A mean ultrahigh molecular weight polyethylene inlay wear rate of 0.53 mg per million cycles (standard = 0.13 mg per 10(6) cycles) was found after 10(7) cycles. All inferior plates showed slight scratching after 10(7) cycles. The impingement wear simulation introduced here proved to be suitable to predict in vivo impingement behavior in regard to the contact pattern seen on retrieved devices of the Pretic-I disk arthroplasty design in a preclinical test.
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China.
authors.forename: Wenjie
authors.initials: W
authors.lastname: Wu
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China.
authors.forename: Jingtong
authors.initials: J
authors.lastname: Lyu
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China liuhao6304@163.com.
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Rong
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China.
authors.forename: Beiyu
authors.initials: B
authors.lastname: Wang
authors.affiliation: Operating Room Chengdu, West China Hospital, Chengdu, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Hong
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Gong
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China.
authors.forename: Limin
authors.initials: L
authors.lastname: Liu
authors.affiliation: Spine Center of Orthopaedic Department, West Hospital, Chengdu, China.
authors.forename: Yueming
authors.initials: Y
authors.lastname: Song
authors.affiliation: The Chuang Sheng Medical (China) of Yangtze River Test Center, Changzhou, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Cai
authors.affiliation: The Chuang Sheng Medical (China) of Yangtze River Test Center, Changzhou, China.
authors.forename: Wenli
authors.initials: W
authors.lastname: Xu
mesh_terms: D000328:Adult; D000497:Alloys; D001696:Biomechanical Phenomena / Q000502:physiology; D002574:Cervical Vertebrae / Q000502:physiology*; D019544:Equipment Failure Analysis; D006801:Humans; D007595:Joint Prosthesis; D008962:Models, Theoretical; D011095:Polyethylenes; D011474:Prosthesis Design; D014025:Titanium; D059145:Total Disc Replacement
chemical_list: D000497:Alloys; D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; C031462:titanium alloy (TiAl6V4); D014025:Titanium
keywords: Ti6Al4V; Wear simulation; cervical total disk replacement; pattern of movement; ultra-high-molecular-weight polyethylene