title: Palladium-Catalyzed Triple Successive C-H Functionalization: Direct Synthesis of Functionalized Carbazoles from Indoles.
abstract: A novel Pd(II)-catalyzed approach for the direct synthesis of differentially substituted carbazoles from free (NH) indoles via regioselective triple successive oxidative Heck (Fujiwara-Moritani reaction) has been achieved. It is demonstrated that both electron-deficient and electron-rich alkenes could be used successively for the incorporation of two different functional groups into the product. The proposed mechanistic pathway was well supported by isolating the first and second successive oxidative Heck intermediates as well as by trapping with styrene-d3.
authors.affiliation: †Department of Chemistry, University of Delhi, Delhi 110007, India.|‡School of Physical Sciences (SPS), Jawaharlal Nehru University, Delhi 110067, India.
authors.forename: Akhilesh K
authors.initials: AK
authors.lastname: Verma
authors.affiliation: †Department of Chemistry, University of Delhi, Delhi 110007, India.
authors.forename: Abhinandan K
authors.initials: AK
authors.lastname: Danodia
authors.affiliation: †Department of Chemistry, University of Delhi, Delhi 110007, India.
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Saunthwal
authors.affiliation: †Department of Chemistry, University of Delhi, Delhi 110007, India.
authors.forename: Monika
authors.initials: M
authors.lastname: Patel
authors.affiliation: †Department of Chemistry, University of Delhi, Delhi 110007, India.
authors.forename: Deepak
authors.initials: D
authors.lastname: Choudhary