title: Optimum sevoflurane concentration for I-gel insertion in unpremedicated children.
abstract: OBJECTIVE
  End-tidal concentration of sevoflurane for I-gel insertion in children has not been studied. This study was designed to determine the sevoflurane EC50 and EC95 for I-gel placement in children as compared with classic laryngeal mask airway (CLMA) placement.
  
  
  METHODS
  The design was a prospective, randomized controlled study.
  
  
  METHODS
  The setting was single tertiary care center.
  
  
  METHODS
  Pediatric subjects of either sex aged 1.5-8 years, weighing 10-20 kg having American Society of Anesthesiologists physical status I/II of undergoing elective cataract surgery were included in the study.
  
  
  METHODS
  Induction and maintenance of anesthesia were achieved with sevoflurane and oxygen with preservation of spontaneous breathing. Children were randomly subjected to either I-gel size 2 (group I) or CLMA size 2 (group II) insertion. The target end-tidal sevoflurane concentration (ET SEVO) was maintained for 8-10 minutes before supraglottic airway device was inserted in both the groups. In the first child, the ET SEVO was kept at 2% and was increased or decreased by 0.2% in the next child depending on the previous child's response according to Dixon method. After each supraglottic airway device insertion, child was observed for 1 minute for any "movement" or "no movement."
  
  
  METHODS
  The measurements were EC50 and EC95 for I-gel and CLMA placement in children.
  
  
  RESULTS
  EC50 and EC95 for group I were 0.94% (0.83%-1.06%) and 1.26% (1.12%-1.66%) and for group II were 1.9% (1.70%-2.1%) and 2.54% (2.24%-3.41%), respectively.
  
  
  CONCLUSIONS
  I-gel insertion in children can be accomplished at nearly half ET SEVO (0.94%) of that required for CLMA insertion (1.9%).
authors.affiliation: Anesthesia Department, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Babita
authors.initials: B
authors.lastname: Ghai
authors.affiliation: Anesthesia Department, Post Graduate Institute of Medical Education and Research, Chandigarh, India. Electronic address: sameersethi29@gmail.com.
authors.forename: Sameer
authors.initials: S
authors.lastname: Sethi
authors.affiliation: Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Mohali, Punjab, India.
authors.forename: Deepika
authors.initials: D
authors.lastname: Bansal
authors.affiliation: Ophthalmology Department, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Jagat
authors.initials: J
authors.lastname: Ram
mesh_terms: D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D002387:Cataract Extraction / Q000379:methods; D002648:Child; D002675:Child, Preschool; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal / Q000295:instrumentation / Q000379:methods*; D017214:Laryngeal Masks; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D010100:Oxygen / Q000008:administration & dosage; D011446:Prospective Studies; D000077149:Sevoflurane; D062606:Tertiary Care Centers
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane; D010100:Oxygen
keywords: CLMA; Cataract surgery; I-gel; Sevoflurane; end tidal