title: Phytochemical Investigation of the Constituents Derived from the Australian Plant Macropidia fuliginosa.
abstract: A phytochemical study of the flowers and bulbs derived from the Australian plant Macropidia fuliginosa, involving hyphenated spectroscopic methodologies (HPLC-NMR and HPLC-MS), together with conventional isolation strategies, resulted in the identification of 16 constituents (1, 2, 4-17) representative of six different structural classes. Six new compounds (12-17) were identified from the bulbs of the plant. The isolated compounds were assessed for antimicrobial activity, and compound 8 was found to be more potent against P. aeruginosa than ampicillin.
authors.affiliation: †School of Applied Sciences (Discipline of Chemistry), Health Innovations Research Institute (HIRi), RMIT University, GPO Box 2476 V, Melbourne, Victoria 3001, Australia.
authors.forename: Robert
authors.initials: R
authors.lastname: Brkljača
authors.affiliation: ‡School of Chemistry and Bio21 Institute, The University of Melbourne Melbourne, Victoria 3010, Australia.
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: White
authors.affiliation: †School of Applied Sciences (Discipline of Chemistry), Health Innovations Research Institute (HIRi), RMIT University, GPO Box 2476 V, Melbourne, Victoria 3001, Australia.
authors.forename: Sylvia
authors.initials: S
authors.lastname: Urban
mesh_terms: D001315:Australia; D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry
chemical_list: C000602210:2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-((6-O-(3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl)-beta-D-glucopyranosyl)oxy)-4H-1-benzopyran-4-one; D005419:Flavonoids; D010936:Plant Extracts