title: Malassezia Pneumonia: A Rare Complication of Parenteral Nutrition Therapy.
abstract: Malassezia species (formerly known as Pityrosporum) are part of normal human skin flora and have been associated with benign dermatologic conditions, such as seborrheic dermatitis and tinea versicolor. In rare cases, however, Malassezia has been associated with systemic disease in immunocompromised patients and infants in the neonatal intensive care unit. Malassezia species require long-chain fatty acids for growth and therefore have a known predilection for individuals receiving lipid containing intravenous parenteral nutrition (PN). Systemic infections are characterized by prolonged fevers and illness but can include nonspecific signs and symptoms. We present the diagnosis and management of a rare case of an immunocompetent, nonneonatal, PN-dependent child with Malassezia furfur pneumonia.
authors.affiliation: Indiana University School of Medicine, Indianapolis, Indiana rimbaker@iupui.edu.|Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: Richelle M
authors.initials: RM
authors.lastname: Baker
authors.affiliation: Indiana University School of Medicine, Indianapolis, Indiana.|Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: Ryan J
authors.initials: RJ
authors.lastname: Stegink
authors.affiliation: Indiana University School of Medicine, Indianapolis, Indiana.|Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.|Ryan White Center for Pediatric Infectious Disease, Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: John J
authors.initials: JJ
authors.lastname: Manaloor
authors.affiliation: Indiana University School of Medicine, Indianapolis, Indiana.|Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: Bryan H
authors.initials: BH
authors.lastname: Schmitt
authors.affiliation: Indiana University School of Medicine, Indianapolis, Indiana.|Section of Pulmonary Medicine, Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: John C
authors.initials: JC
authors.lastname: Stevens
authors.affiliation: Indiana University School of Medicine, Indianapolis, Indiana.|Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.|Ryan White Center for Pediatric Infectious Disease, Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: John C
authors.initials: JC
authors.lastname: Christenson
mesh_terms: D002648:Child; D005217:Fat Emulsions, Intravenous / Q000009:adverse effects / Q000737:chemistry; D005260:Female; D054884:Host-Pathogen Interactions; D006801:Humans; D016867:Immunocompromised Host; D007363:Intensive Care Units, Neonatal; D008290:Malassezia / Q000302:isolation & purification*; D010288:Parenteral Nutrition / Q000009:adverse effects*; D011014:Pneumonia / Q000175:diagnosis* / Q000382:microbiology*; D012867:Skin / Q000382:microbiology; D018980:Williams Syndrome / Q000382:microbiology / Q000628:therapy
chemical_list: D005217:Fat Emulsions, Intravenous
keywords: Malassezia; central venous catheter; parenteral nutrition; pneumonia