title: The AKT1 isoform plays a dominant role in the survival and chemoresistance of chronic lymphocytic leukaemia cells.
authors.affiliation: Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.|Salzburg Cancer Research Institute, Salzburg, Austria.
authors.forename: Sebastian W
authors.initials: SW
authors.lastname: Hofbauer
authors.affiliation: Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.|Salzburg Cancer Research Institute, Salzburg, Austria.
authors.forename: Peter W
authors.initials: PW
authors.lastname: Krenn
authors.affiliation: Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.|Salzburg Cancer Research Institute, Salzburg, Austria.
authors.forename: Josefina
authors.initials: J
authors.lastname: Piñόn Hofbauer
authors.affiliation: Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.|Salzburg Cancer Research Institute, Salzburg, Austria.
authors.forename: Susanne
authors.initials: S
authors.lastname: Pucher
authors.affiliation: Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.|Salzburg Cancer Research Institute, Salzburg, Austria.
authors.forename: Daniela
authors.initials: D
authors.lastname: Asslaber
authors.affiliation: Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.|Salzburg Cancer Research Institute, Salzburg, Austria.
authors.forename: Alexander
authors.initials: A
authors.lastname: Egle
authors.affiliation: Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria. t.hartmann@salk.at.|Salzburg Cancer Research Institute, Salzburg, Austria. t.hartmann@salk.at.
authors.forename: Tanja N
authors.initials: TN
authors.lastname: Hartmann
authors.affiliation: Laboratory for Immunological and Molecular Cancer Research, 3rd Medical Department with Haematology, Medical Oncology, Haemostaseology, Infectiology and Rheumatology, Oncological Centre, Paracelsus Medical University, Salzburg, Austria.|Salzburg Cancer Research Institute, Salzburg, Austria.
authors.forename: Richard
authors.initials: R
authors.lastname: Greil
mesh_terms: D002470:Cell Survival / Q000502:physiology; D019008:Drug Resistance, Neoplasm / Q000502:physiology; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000378:metabolism*; D020033:Protein Isoforms / Q000502:physiology; D051057:Proto-Oncogene Proteins c-akt / Q000502:physiology*; D014407:Tumor Cells, Cultured
chemical_list: D020033:Protein Isoforms; C494918:AKT1 protein, human; D051057:Proto-Oncogene Proteins c-akt
keywords: AKT; chemoresistance; chronic lymphocytic leukaemia; microenvironment; survival