title: Indian Council of Medical Research consensus document for the management of gall bladder cancer.
abstract: The document is based on consensus among the experts and best available evidence pertaining to Indian population and is meant for practice in India.All postcholecystectomy gallbladder specimens should be opened and examined carefully by the operating surgeon and be sent for histopathological examination.All "incidental" gall bladder cancers (GBCs) picked up on histopathological examination should have an expert opinion.Evaluation of a patient with early GBC should include essential tests: A computed tomography (CT) scan (multi-detector or helical) of the abdomen and pelvis for staging with a CT chest or chest X-ray, and complete blood counts, renal and liver function tests. magnetic resonance imaging/positron emission tomography (PET)-CT are not recommended for all patients.For early stage disease (up to Stage IVA), surgery is recommended. The need for adjuvant treatment would be guided by the histopathological analysis of the resected specimen.Patients with Stage IVB/metastatic disease must be assessed for palliative e.g. endoscopic or radiological intervention, chemotherapy versus best supportive care on an individual basis. These patients do not require extensive workup outside of a clinical trial setting.There is an urgent need for multicenter trials from India covering various aspects of epidemiology (viz., identification of population at high-risk, organized follow-up), clinical management (viz., bile spill during surgery, excision of all port sites, adjuvant/neoadjuvant therapy) and basic research (viz., what causes GBC).
authors.affiliation: Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Hari Shankar
authors.initials: HS
authors.lastname: Shukla
authors.affiliation: Mazumdar Shaw Cancer Centre, Narayana Health, Bengaluru, Karnataka, India.
authors.forename: Bhawna
authors.initials: B
authors.lastname: Sirohi
authors.affiliation: Department of GI Surgery, SGPGI, Lucknow, Uttar Pradesh, India.
authors.forename: Anu
authors.initials: A
authors.lastname: Behari
authors.affiliation: Department of Medical Oncology, IRCH, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Atul
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India.
authors.forename: Jahar
authors.initials: J
authors.lastname: Majumdar
authors.affiliation: Department of Surgery, Army Hospital, Rohtak, Haryana, India.
authors.forename: Manomoy
authors.initials: M
authors.lastname: Ganguly
authors.affiliation: Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Mallika
authors.initials: M
authors.lastname: Tewari
authors.affiliation: All India Institute of Medical Sciences, Saket Nagar, Bhopal, Madhya Pradesh, India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Kumar
authors.affiliation: HIMS, Jolly Grant, Dehradun, Uttarakhand, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Saini
authors.affiliation: Department of GI Surgery, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Peush
authors.initials: P
authors.lastname: Sahni
authors.affiliation: Department of Radiotherapy, RIMS, Imphal, Manipur, India.
authors.forename: Tomcha
authors.initials: T
authors.lastname: Singh
authors.affiliation: Department of GI Surgery, SGPGI, Lucknow, Uttar Pradesh, India.
authors.forename: Vinay Kumar
authors.initials: VK
authors.lastname: Kapoor
authors.affiliation: Indian Council of Medical Research, New Delhi, India.
authors.forename: V
authors.initials: V
authors.lastname: Sucharita
authors.affiliation: Indian Council of Medical Research, New Delhi, India.
authors.forename: Tanvir
authors.initials: T
authors.lastname: Kaur
authors.affiliation: Indian Council of Medical Research, New Delhi, India.
authors.forename: Deepak Kumar
authors.initials: DK
authors.lastname: Shukla
authors.affiliation: Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Goura Kishor
authors.initials: GK
authors.lastname: Rath
keywords: Gall bladder cancer; ICMR; guidelines; treatmemt