title: Whole-Genome Sequencing Analysis of Sapovirus Detected in South Korea.
abstract: Sapovirus (SaV), a virus residing in the intestines, is one of the important causes of gastroenteritis in human beings. Human SaV genomes are classified into various genogroups and genotypes. Whole-genome analysis and phylogenetic analysis of ROK62, the SaV isolated in South Korea, were carried out. The ROK62 genome of 7429 nucleotides contains 3 open-reading frames (ORF). The genotype of ROK62 is SaV GI-1, and 94% of its nucleotide sequence is identical with other SaVs, namely Manchester and Mc114. Recently, SaV infection has been on the rise throughout the world, particularly in countries neighboring South Korea; however, very few academic studies have been done nationally. As the first whole-genome sequence analysis of SaV in South Korea, this research will help provide reference for the detection of recombination, tracking of epidemic spread, and development of diagnosis methods for SaV.
authors.affiliation: Department of Microbiology, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, Republic of Korea.
authors.forename: Hye Lim
authors.initials: HL
authors.lastname: Choi
authors.affiliation: Department of Medical Consilience, 152, Dankook University, Jukjeon-ro, Suji-gu, Yongin-si, Gyeonggi-do, 448-701, Republic of Korea.
authors.forename: Chang-Il
authors.initials: CI
authors.lastname: Suh
authors.affiliation: Division of Biotechnology, Catholic University of Daegu, Daegu, 712-702, Republic of Korea.
authors.forename: Seung-Won
authors.initials: SW
authors.lastname: Park
authors.affiliation: Department of Microbiology, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, Republic of Korea.
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: Jin
authors.affiliation: Division of Public Health Research, Gyeonggi Province Institute of Health and Environment, Suwon, Republic of Korea.
authors.forename: Han-Gil
authors.initials: HG
authors.lastname: Cho
authors.affiliation: Department of Microbiology, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 137-701, Republic of Korea.
authors.forename: Soon-Young
authors.initials: SY
authors.lastname: Paik
mesh_terms: D001483:Base Sequence; D005260:Female; D016679:Genome, Viral; D006801:Humans; D007223:Infant; D016366:Open Reading Frames / Q000235:genetics; D010802:Phylogeny; D056910:Republic of Korea; D029341:Sapovirus / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*