title: DNA modulates solvent isotope effects in a nanopore.
abstract: Here we investigate the modulation of solvent isotope effects by the entry of DNA molecules into individual α-haemolysin nanopores. Solvent isotope effects in D2O versus H2O were enhanced (kH/kD ≈ 1.6) compared to the bulk (kH/kD ≈ 1.2), except when the pore was most blocked (kH/kD ≤ 1.1).
authors.affiliation: EaStCHEM School of Chemistry, University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh, EH9 3FJ, UK. scott.cockroft@ed.ac.uk.
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Watson
authors.forename: Scott L
authors.initials: SL
authors.lastname: Cockroft
mesh_terms: D004277:DNA, Single-Stranded / Q000737:chemistry*; D017666:Deuterium Oxide / Q000737:chemistry*; D006460:Hemolysin Proteins / Q000737:chemistry*; D058608:Nanopores; D012997:Solvents / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D004277:DNA, Single-Stranded; D006460:Hemolysin Proteins; D012997:Solvents; D014867:Water; D017666:Deuterium Oxide