title: Transcatheter Therapies for the Treatment of Valvular and Paravalvular Regurgitation in Acquired and Congenital Valvular Heart Disease.
abstract: Transcatheter therapies in structural heart disease have evolved tremendously over the past 15 years. Since the introduction of the first balloon-expandable valves for stenotic lesions with implantation in the pulmonic position in 2000, treatment for valvular heart disease in the outflow position has become more refined, with newer-generation devices, alternative techniques, and novel access approaches. Recent efforts into the inflow position and regurgitant lesions, with transcatheter repair and replacement technologies, have expanded our potential to treat a broader, more heterogeneous patient population. The evolution of multimodality imaging has paralleled these developments. Three- and 4-dimensional visualization and concomitant use of novel technologies, such as fusion imaging, have supported technical growth, from pre-procedural planning and intraprocedural guidance, to assessment of acute results and follow-up. A multimodality approach has allowed operators to overcome many limitations of each modality and facilitated integration of a multidisciplinary team for treatment of this complex patient population.
authors.affiliation: Lenox Hill Heart and Vascular Institute of New York-Hofstra School of Medicine, New York, New York. Electronic address: cruizmd@gmail.com.
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Ruiz
authors.affiliation: Lenox Hill Heart and Vascular Institute of New York-Hofstra School of Medicine, New York, New York.
authors.forename: Chad
authors.initials: C
authors.lastname: Kliger
authors.affiliation: Lenox Hill Heart and Vascular Institute of New York-Hofstra School of Medicine, New York, New York.
authors.forename: Gila
authors.initials: G
authors.lastname: Perk
authors.affiliation: Department of Cardiothoracic Surgery, University Hospital of Zurich, Zurich, Switzerland.
authors.forename: Francesco
authors.initials: F
authors.lastname: Maisano
authors.affiliation: Department of Cardiology, Mayo Clinic, Rochester, Minnesota.
authors.forename: Allison K
authors.initials: AK
authors.lastname: Cabalka
authors.affiliation: Boston Children's Hospital, Adult Congenital Heart Disease, Harvard University, Boston, Massachusetts.
authors.forename: Michael
authors.initials: M
authors.lastname: Landzberg
authors.affiliation: Department of Cardiology, Mayo Clinic, Rochester, Minnesota.
authors.forename: Chet
authors.initials: C
authors.lastname: Rihal
authors.affiliation: Lenox Hill Heart and Vascular Institute of New York-Hofstra School of Medicine, New York, New York.
authors.forename: Itzhak
authors.initials: I
authors.lastname: Kronzon
mesh_terms: D001022:Aortic Valve Insufficiency / Q000628:therapy; D006328:Cardiac Catheterization; D003952:Diagnostic Imaging; D006349:Heart Valve Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006350:Heart Valve Prosthesis; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000628:therapy; D011665:Pulmonary Valve Insufficiency / Q000628:therapy; D014262:Tricuspid Valve Insufficiency / Q000628:therapy
keywords: aortic regurgitation; mitral regurgitation; pulmonic regurgitation; transcatheter valve technology; tricuspid regurgitation