title: EXTENT AND LOCATION OF INTRARETINAL AND SUBRETINAL FLUID AS PROGNOSTIC FACTORS FOR THE OUTCOME OF PATIENTS WITH OPTIC DISK PIT MACULOPATHY.
abstract: OBJECTIVE
  To determine if baseline fundoscopic and optical coherence tomography (OCT) features influence the clinical course of optic disk pit maculopathy.
  
  
  METHODS
  A multicenter retrospective case note review was undertaken, using standardized OCT and clinical data collection. Visual success was defined as at least a two-line visual acuity improvement, anatomical success as full resolution of OCT foveal fluid with restoration of the normal foveal contour, and partial anatomical success as incomplete resolution of the OCT foveal fluid. Outcomes were compared with a synthesis of the literature, using similar eligibility criteria.
  
  
  RESULTS
  Of 36 patients (36 eyes), 2 spontaneously improved and 34 underwent surgery. Visual success was achieved in 64% of surgical cases, anatomical success in 36%, and partial anatomical success in 47%. Cases with multilayer intraretinal and subretinal fluid were less likely to have visual success (P = 0.003). Cases where the fluid did not extend to the macular arcade vessels also had better visual and anatomical outcomes (P = 0.004 and 0.005, respectively).
  
  
  CONCLUSIONS
  Fundoscopic and OCT features can help predict surgical outcome in optic disk pit maculopathy.
authors.affiliation: *Sunderland Eye Infirmary, Sunderland, United Kingdom; †Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom; ‡Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom; §Faculty of Applied Sciences, University of Sunderland, Sunderland, United Kingdom; ¶Moorfields Eye Hospital, London, United Kingdom; **Manchester Royal Eye Hospital, Manchester, United Kingdom; ††Oxford Eye Hospital, Oxford Radcliffe Hospitals NHS Trust, Oxford, United Kingdom; ‡‡Department of Ophthalmology, Radboud University Medical Center, Nijmegen, the Netherlands; §§Department of Ophthalmology, Musgrove Park Hospital, Taunton, United Kingdom; and ¶¶Department of Ophthalmology, School of Medicine, King's College London, London, United Kingdom.
authors.forename: David H W
authors.initials: DH
authors.lastname: Steel
authors.forename: Tom H
authors.initials: TH
authors.lastname: Williamson
authors.forename: D Alistair H
authors.initials: DA
authors.lastname: Laidlaw
authors.forename: Priyanka
authors.initials: P
authors.lastname: Sharma
authors.forename: Christopher
authors.initials: C
authors.lastname: Matthews
authors.forename: Jon
authors.initials: J
authors.lastname: Rees
authors.forename: Petros
authors.initials: P
authors.lastname: Petrou
authors.forename: David G
authors.initials: DG
authors.lastname: Charteris
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Charles
authors.forename: C K
authors.initials: CK
authors.lastname: Patel
authors.forename: Niels
authors.initials: N
authors.lastname: Crama
authors.forename: Ed
authors.initials: E
authors.lastname: Herbert
authors.forename: Timothy L
authors.initials: TL
authors.lastname: Jackson
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005124:Eye Abnormalities / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019721:Ophthalmoscopes; D009898:Optic Disk / Q000002:abnormalities*; D011379:Prognosis; D012164:Retinal Diseases / Q000175:diagnosis* / Q000601:surgery; D012189:Retrospective Studies; D058471:Subretinal Fluid; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy