title: [Syncope: physiopathology, diagnosis and therapy].
abstract: Nowadays, syncope still generates complicated challenges for clinicians for the alarm it arises in patients and, at the same time, for the multiple causes it has determined by. In almost one third of cases, syncope is neuromediated, in young subjects in vasovagal, whereas in elderly is often determinated by carotid sinus hypersensitivity. These two kinds of syncope have two completely different diagnostic approach. In some cases pace-maker implantation will be suggested to avoid new syncope episodes. In a 20% of cases, the underlying cause is arrhythmic, most of all bradiarrhythmia which is treated with pace-maker implantation. In a little number of cases, syncope is caused by ventricular arrhythmias, that require the implantation of a defibrillator device. In this review, we analyze in detail every cause of syncope with its diagnostic and therapeutic approach.
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Policlinico Umberto I, "Sapienza" University of Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Piccirillo
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Policlinico Umberto I, "Sapienza" University of Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Moscucci
authors.affiliation: Dipartimento di Medicina Clinica e Molecolare - Azienda Ospedaliera Sant' Andrea, University of Rome, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Magrì
mesh_terms: D000367:Age Factors; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology; D005260:Female; D006801:Humans; D013575:Syncope / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*
keywords: QT; QTVI; Repolarization; Sudden cardiac death