title: Hemodynamic Changes in Patients Undergoing Pericardiectomy.
abstract: To observe the hemodynamic changes in patients undergoing pericardiectomy at different operational stages.
  
  
  
  Totally 16 consecutive patients receiving radical pericardiectomy were enrolled in this observational study. Hemodynamic variables were monitored continuously by pulse-indicated continuous cardiac output(PiCCO)system. Totally,three sets of intraoperative hemodynamic parameters were obtained at three different stages of pericardiectomy.
  
  
  
  During the pericardiectomy,the cardiac index[CI,(1.9±0.6),(2.7±0.6),(3.0±0.5)L·min(-1)·m(-2);P<0.05]and stroke volume index[SI,(22.5±8.7),(29.9±8.5),(30.1±8.5)dyn·s·cm(-5)·m(2);P<0.05]showed significant improvement,whereas central venous pressure[CVP,(17.1±5.0),(13.3±3.9),(12.3±3.0)mmHg;P<0.05]decreased significantly. Global end-diastolic volume index[GEDVi,(533±156),(580±153),(559±144)ml·m(-2);P<0.05]increased and stroke volume variation[SVV,(15.6±6.1)%,(10.8±4.2)%,(9.4±5.4)%;P<0.05]decreased intra-operatively. The majority of the above-mentioned hemodynamic improvements occurred after the resection of pericardium over the left ventricular outflow tract(LVOT).
  
  
  
  PiCCO system can serve as a reliable,less invasive hemodynamic monitoring method during pericardiectomy. Resection of the pericardium over the LVOT is the most important step of the pericardiectomy.
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Xia
authors.initials: X
authors.lastname: Ruan
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Li-Jian
authors.initials: LJ
authors.lastname: Pei
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Guang-Jun
authors.initials: GJ
authors.lastname: Chen
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Jing-Jie
authors.initials: JJ
authors.lastname: Wang
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Yu-Guang
authors.initials: YG
authors.lastname: Huang
mesh_terms: D002302:Cardiac Output; D006321:Heart; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D010492:Pericardiectomy; D013318:Stroke Volume