title: Brain Wiring in the Fourth Dimension.
abstract: In this issue of Cell, Langen et al. use time-lapse multiphoton microscopy to show how Drosophila photoreceptor growth cones find their targets. Based on the observed dynamics, they develop a simple developmental algorithm recapitulating the highly complex connectivity pattern of these neurons, suggesting a basic framework for establishing wiring specificity.
authors.affiliation: Center for Genomics and Systems Biology, New York University Abu Dhabi (NYUAD), 129188 Saadiyat Island, Abu Dhabi, UAE.
authors.forename: Mathias F
authors.initials: MF
authors.lastname: Wernet
authors.affiliation: Center for Genomics and Systems Biology, New York University Abu Dhabi (NYUAD), 129188 Saadiyat Island, Abu Dhabi, UAE; Department of Biology, New York University, 100 Washington Square East, New York, NY 10003, USA. Electronic address: cd38@nyu.edu.
authors.forename: Claude
authors.initials: C
authors.lastname: Desplan
mesh_terms: D000818:Animals; D001369:Axons; D054910:Compound Eye, Arthropod / Q000294:innervation*; D003198:Computer Simulation; D004330:Drosophila / Q000254:growth & development*; D017956:Photoreceptor Cells, Invertebrate / Q000502:physiology*