title: The influence of sex on outcomes in trauma patients: a meta-analysis.
abstract: BACKGROUND
  This study aims to assess the influence of sex on outcomes among trauma patients, including injury severity, medical resource utility, complications, and mortality.
  
  
  METHODS
  A systematic review of the literature was conducted by internet search. Data were extracted from selected studies and analyzed using Stata to compare outcomes between male and female injured patients.
  
  
  RESULTS
  Eventually, 19 studies met our inclusion criteria with 100,566 men and 39,762 women. Pooled data revealed that male sex was associated with increased risk of mortality, hospital length of stay, and higher incidence of complications. No difference was detected in injury severity between male and female patients.
  
  
  CONCLUSIONS
  Evidence of this meta-analysis strongly supports the sex dimorphism in the prognosis of trauma patients and further work should be done to decipher potential mechanism.
authors.affiliation: Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Liu
authors.affiliation: Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Xie
authors.affiliation: Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China.
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.affiliation: Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China.
authors.forename: Jia-jun
authors.initials: JJ
authors.lastname: Chen
authors.affiliation: Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China.
authors.forename: Zhan-fei
authors.initials: ZF
authors.lastname: Li
authors.affiliation: Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China.
authors.forename: Cheng-la
authors.initials: CL
authors.lastname: Yi
authors.affiliation: Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Gao
authors.affiliation: Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430034, China. Electronic address: baixiangjun@hotmail.com.
authors.forename: Xiang-jun
authors.initials: XJ
authors.lastname: Bai
mesh_terms: D005260:Female; D006801:Humans; D015601:Injury Severity Score; D007902:Length of Stay; D008297:Male; D009102:Multiple Organ Failure / Q000453:epidemiology*; D011379:Prognosis; D018805:Sepsis / Q000453:epidemiology*; D012737:Sex Factors; D014947:Wounds and Injuries / Q000150:complications / Q000401:mortality*
keywords: Prognosis; Sex; Sex hormone; Trauma