title: Recent advances in Brucella abortus vaccines.
abstract: Brucella abortus vaccines play a central role in bovine brucellosis control/eradication programs and have been successfully used worldwide for decades. Strain 19 and RB51 are the approved B. abortus vaccines strains most commonly used to protect cattle against infection and abortion. However, due to some drawbacks shown by these vaccines much effort has been undertaken for the development of new vaccines, safer and more effective, that could also be used in other susceptible species of animals. In this paper, we present a review of the main aspects of the vaccines that have been used in the brucellosis control over the years and the current research advances in the development of new B. abortus vaccines.
authors.affiliation: Departamento de Medicina Veterinária Preventiva, Escola de Veterinária, Laboratório de Bacteriologia Aplicada, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. selesdorneles@yahoo.com.br.
authors.forename: Elaine M S
authors.initials: EM
authors.lastname: Dorneles
authors.affiliation: Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA. nathans@vt.edu.
authors.forename: Nammalwar
authors.initials: N
authors.lastname: Sriranganathan
authors.affiliation: Departamento de Medicina Veterinária Preventiva, Escola de Veterinária, Laboratório de Bacteriologia Aplicada, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. alage@vet.ufmg.br.
authors.forename: Andrey P
authors.initials: AP
authors.lastname: Lage
mesh_terms: D000034:Abortion, Veterinary / Q000517:prevention & control*; D000818:Animals; D002004:Brucella Vaccine / Q000276:immunology*; D002003:Brucella abortus / Q000276:immunology*; D002007:Brucellosis, Bovine / Q000517:prevention & control*; D002417:Cattle; D005260:Female; D011247:Pregnancy
chemical_list: D002004:Brucella Vaccine