title: Synthesis, structure, and tuberculostatic activity of dimethyl benzoylcarbonohydrazonodithioates.
abstract: New dimethyl benzoylcarbonohydrazonodithioates were obtained by CS2addition to arylcarboxylic acid hydrazides and methylation of the formed adduct. The new derivatives were tested for their activity againstMycobacterium tuberculosis. Some compounds exhibited high activity toward sensitive and resistant strains.
authors.affiliation: Department of Organic Chemistry, Medical University of Gdansk, Gdansk, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Gobis
authors.affiliation: Department of Organic Chemistry, Medical University of Gdansk, Gdansk, Poland.
authors.forename: Henryk
authors.initials: H
authors.lastname: Foks
authors.affiliation: Department of Microbiology, Institute of Tuberculosis and Pulmonary Diseases, Warsaw, Poland.
authors.forename: Zofia
authors.initials: Z
authors.lastname: Zwolska
authors.affiliation: Department of Microbiology, Institute of Tuberculosis and Pulmonary Diseases, Warsaw, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Augustynowicz-Kopeć
authors.affiliation: Institute of General and Ecological Chemistry, Technical University of Łódź, Łódź, Poland.
authors.forename: Marek L
authors.initials: ML
authors.lastname: Główka
authors.affiliation: Institute of General and Ecological Chemistry, Technical University of Łódź, Łódź, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Olczak
authors.affiliation: Department of Pharmaceutical Technology and Biochemistry, Gdansk University of Technology, Gdansk, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Sabisz
keywords: Benzohydrazides; Crystal structure; Hydrogen bonds; Structure–activity relationship; Tuberculostatic activity