title: Shape-based Automatic Detection of Pectoral Muscle Boundary in Mammograms.
abstract: The detection of the pectoral muscle boundary in the medio-lateral oblique view of mammograms is essential to improving the computer-aided diagnosis of breast cancer. In this study, a shape-based detection method is proposed for accurately extracting the boundary of the pectoral muscle in mammograms. A shape-based enhancement mask is applied to the mammogram and the initial boundary is then defined using morphological operators. The seed point is then detected on the initial boundary and the pectoral boundary is evolved from candidate points produced using a shape-based growth strategy. A cubic polynomial fitting function is implemented to obtain the final pectoral muscle boundary. The proposed method was applied to 322 mammograms from the mini Mammographic Image Analysis Society database. A 97.2 % acceptable rate from expert radiologists and assessment results based on the false positive rate, false negative rate, and Hausdorff distance demonstrate the robustness and effectiveness of the proposed shape-based detection method.
authors.affiliation: Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016 China.
authors.forename: Chunxiao
authors.initials: C
authors.lastname: Chen
authors.affiliation: Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016 China.
authors.forename: Gao
authors.initials: G
authors.lastname: Liu
authors.affiliation: Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016 China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110 USA.
authors.forename: Gail
authors.initials: G
authors.lastname: Sudlow
keywords: Boundary detection; Mammogram; Pectoral muscle; Shape-based mask