title: Spectrum of Imaging Findings in Paget's Disease of the Breast-A Pictorial Review.
abstract: OBJECTIVE
  We aimed to demonstrate imaging features of Paget's disease of breast, which is an extremely uncommon malignancy that presents with changes in the nipple-areolar region that may or may not be associated with an underlying in situ component or invasive cancer.
  
  
  RESULTS
  Mammography is the initial investigation of choice, having a high sensitivity especially in cases where a palpable mass is present. The addition of ultrasound improves the accuracy of mammography. When both mammography and ultrasound are negative, MRI may detect an underlying mass or ductal carcinoma in situ (DCIS).
  
  
  CONCLUSIONS
  The surgical management of Paget's disease includes mastectomy with or without axillary dissection, though breast conservation surgery in the form of wide local excision can also be done in a selected group of patients. Management should be based on both clinical and imaging findings, including mammography and ultrasound, with MRI playing a crucial role in defining the extent of involvement. Teaching Points • To differentiate Paget's disease from other chronic skin conditions. • Mammographic and ultrasound findings of histopathologically established Paget's disease. • When ultrasound and mammogram are negative, MRI may detect underlying malignancy.
authors.affiliation: Department of Radiodiagnosis and Imaging, Kasturba Medical College, Manipal, Karnataka, India, smitis11@hotmail.com.
authors.forename: Smiti
authors.initials: S
authors.lastname: Sripathi
authors.forename: Anurag
authors.initials: A
authors.lastname: Ayachit
authors.forename: Rajagopal
authors.initials: R
authors.lastname: Kadavigere
authors.forename: Sandeep
authors.initials: S
authors.lastname: Kumar
authors.forename: Asha
authors.initials: A
authors.lastname: Eleti
authors.forename: Aron
authors.initials: A
authors.lastname: Sraj