title: Cu²⁺ functionalized N-acetyl-L-cysteine capped CdTe quantum dots as a novel resonance Rayleigh scattering probe for the recognition of phenylalanine enantiomers.
abstract: A simple protocol that can be used to simultaneously determinate enantiomers is extremely intriguing and useful. In this study, we proposed a low-cost, facile, sensitive method for simultaneous determination. The molecular recognition of Cu(2+) functionalized N-acetyl-l-cysteine capped CdTe quantum dots (Cu(2+)-NALC/CdTe QDs) with phenylalanine (PA) enantiomers was investigated based on the resonance Rayleigh scattering (RRS) spectral technique. The RRS intensity of NALC/CdTe QDs is very weak, but Cu(2+) functionalized NALC/CdTe QDs have extremely high RRS intensity, the most important observations are that PA could quench the RRS intensity of Cu(2+)-NALC/CdTe QDs, and that l-PA and d-PA have different degree of influence. In addition, those experimental factors such as acidity, concentration of Cu(2+) and reaction time were investigated in regards to their effects on enantioselective interaction. Finally, the applicability of the chiral recognized sensor for the analysis of chiral mixtures on enantiomers has been demonstrated, and the results that were obtained high precision (<4.63%) and low error (<3.06%).
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China; School of Chemistry and Environmental Engineering, Chongqing Three Gorges University, Wanzhou, Chongqing 404000, China. Electronic address: flyjd6400@163.com.
authors.forename: Jidong
authors.initials: J
authors.lastname: Yang
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Xuanping
authors.initials: X
authors.lastname: Tan
authors.affiliation: Department of Mathematics, Sciences & Technology, Paine College, 1235 Fifteenth Street, Augusta, GA 30901, United Sates.
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing, Fuling 408100, China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Yang
authors.affiliation: School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Yizhong
authors.initials: Y
authors.lastname: Shen
mesh_terms: D000111:Acetylcysteine / Q000737:chemistry*; D019187:Cadmium Compounds / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D010649:Phenylalanine / Q000032:analysis* / Q000737:chemistry*; D045663:Quantum Dots; D012542:Scattering, Radiation; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism; D013691:Tellurium / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D010649:Phenylalanine; D003300:Copper; D013691:Tellurium; C028337:cadmium telluride; D000111:Acetylcysteine
keywords: Cu(2+); Functionalized; N-acetyl-l-cysteine capped CdTe quantum dots; Resonance Rayleigh scattering; d-phenylalanine; l-phenylalanine