title: Amoebic liver abscess: a report from central India.
abstract: Amoebic liver abscess is a serious but curable hepatic illness predominantly seen in tropical countries. We describe our experience of clinical presentation, laboratory parameters, radiological findings and treatment strategies. This is a retrospective analysis of 114 patients who were admitted from January 2012 to September 2014 at our centre. The mean age of presentation was 41.7 ± 13.9 years, the majority of patients were male (86.8%) with chronic alcoholism (63.2%). Most of the patients had a solitary right lobe liver abscess. Abdominal pain, fever, tachycardia and hepatomegaly were the most common clinical findings while hypoalbuminaemia, anaemia, leucocytosis and electrolyte imbalance were the most common laboratory abnormalities. A significant number of patients could be managed with antibiotics only (45.6%), percutaneous radiological drainage techniques being an important adjunct in selected cases (percutaneous needle aspiration, 20.2%; percutaneous pigtail catheter drainage, 30.7%). Surgical intervention was required in only a few cases (3.5%). Mortality was 3.5%.
authors.affiliation: Department of Gastroenterology, Sri Aurobindo Medical College and P.G. Institute, Indore, Madhya Pradesh, India.
authors.forename: Satyarth
authors.initials: S
authors.lastname: Chaudhary
authors.affiliation: Department of Gastroenterology, Sri Aurobindo Medical College and P.G. Institute, Indore, Madhya Pradesh, India noorpgi@gmail.com.
authors.forename: Mohd Talha
authors.initials: MT
authors.lastname: Noor
authors.affiliation: Department of Gastroenterology, Sri Aurobindo Medical College and P.G. Institute, Indore, Madhya Pradesh, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Jain
authors.affiliation: Central Research Laboratory, Sri Aurobindo Medical College and P.G. Institute, Indore, Madhya Pradesh, India.
authors.forename: Ravindra
authors.initials: R
authors.lastname: Kumar
authors.affiliation: Department of Gastroenterology, Sri Aurobindo Medical College and P.G. Institute, Indore, Madhya Pradesh, India.
authors.forename: Bhagwan Singh
authors.initials: BS
authors.lastname: Thakur
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004322:Drainage; D004748:Entamoeba histolytica / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008101:Liver Abscess, Amebic / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents
keywords: Liver abscess; amoebiasis; clinical profile