title: Visual acuity at presentation in the second eye versus first eye in patients with exudative age-related macular degeneration.
abstract: OBJECTIVE
  To assess the difference in best-corrected visual acuity (BCVA) at presentation between the first and second eye in patients with bilateral neovascular age-related macular degeneration (AMD).
  
  
  METHODS
  We reviewed the charts of all patients who had a clinical examination for neovascular AMD at the University Eye Clinic of Creteil in January 2013. We retrospectively analyzed demographic and clinical data for 264 patients.
  
  
  RESULTS
  In the fellow eye, choroidal neovascularization (CNV) developed in 75/264 patients (28.4%) with a time interval between the 2 events of 30.3 months (range 6-145). Data were available on 65 patients: 14/65 (21.5%) were asymptomatic, 24/65 (36.9%) had BCVA >20/40, whereas at the time of CNV diagnosis in the first eye, no patient was asymptomatic (p<0.0001), and 11/65 (16.9%) eyes had BCVA >20/40 (p<0.0001). The mean BCVA of the first affected eye was 0.68 (± 0.41) logarithm of minimum angle of resolution (logMAR) and the mean BCVA for the second eye was 0.36 (± 0.29) logMAR (p<0.0001).
  
  
  CONCLUSIONS
  The BCVA at the time of diagnosis of CNV was higher in the second eye than in the first affected eye. This was possibly due to several factors including systematic bilateral examination in follow-up of unilateral exudative AMD that allowed detection of 20% of cases.
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, Creteil - France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Chevreaud
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, Creteil - France.
authors.forename: Oudy
authors.initials: O
authors.lastname: Semoun
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, Creteil - France.|Centre de Recherche Clinique, Centre Hospitalier Intercommunal de Creteil, Creteil - France.
authors.forename: Rocio
authors.initials: R
authors.lastname: Blanco-Garavito
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, Creteil - France.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Kamami-Levy
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, Creteil - France.|Centre de Recherche Clinique, Centre Hospitalier Intercommunal de Creteil, Creteil - France.
authors.forename: Benedicte
authors.initials: B
authors.lastname: Merle
authors.affiliation: Centre de Recherche Clinique, Centre Hospitalier Intercommunal de Creteil, Creteil - France.
authors.forename: Camille
authors.initials: C
authors.lastname: Jung
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, Creteil - France.|Centre de Recherche Clinique, Centre Hospitalier Intercommunal de Creteil, Creteil - France.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Querques
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, Creteil - France.|Centre de Recherche Clinique, Centre Hospitalier Intercommunal de Creteil, Creteil - France.
authors.forename: Eric H
authors.initials: EH
authors.lastname: Souied
mesh_terms: D000368:Aged; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005584:Fovea Centralis; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology*; D057135:Wet Macular Degeneration / Q000175:diagnosis* / Q000503:physiopathology*