title: Skeletal complications of eating disorders.
abstract: Anorexia nervosa (AN) is a psychiatric illness with profound medical consequences. Among the many adverse physical sequelae of AN, bone health is impacted by starvation and can be permanently impaired over the course of the illness. In this review of skeletal complications associated with eating disorders, we discuss the epidemiology, neuroendocrine changes, adolescent vs. adult skeletal considerations, orthopedic concerns, assessment of bone health, and treatment options for individuals with AN. The focus of the review is the skeletal sequelae associated with anorexia nervosa, but we also briefly consider other eating disorders that may afflict adolescents and young adults. The review presents updates to the field of bone health in AN, and also suggests knowledge gaps and areas for future investigation.
authors.affiliation: Hasbro Children's Hospital and Alpert Medical School of Brown University, Providence, RI. Electronic address: adonaldson@lifespan.org.
authors.forename: Abigail A
authors.initials: AA
authors.lastname: Donaldson
authors.affiliation: Hasbro Children's Hospital and Alpert Medical School of Brown University, Providence, RI. Electronic address: cgordon1@lifespan.org.
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Gordon
mesh_terms: D000293:Adolescent; D000856:Anorexia Nervosa / Q000150:complications* / Q000453:epidemiology; D001847:Bone Diseases / Q000175:diagnosis / Q000209:etiology*; D001068:Feeding and Eating Disorders / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000209:etiology; D055815:Young Adult
keywords: Anorexia nervosa; Bone health; Bone mineral density; Eating disorder