title: Gold-catalyzed intramolecular diazo coupling: an efficient macrocyclization towards cyclic olefins.
abstract: A gold-catalyzed intramolecular coupling of diazo compounds to produce cyclic olefins has been well established. The medium and large sized membered olefins were obtained in moderate to good yields. Notably, the Z/E selectivity of the olefins highly depended on the ring size. Furthermore, this investigation indicated that the structure of the phosphorous ligand binding to the gold centre played a vital role in the reaction efficiency. Also, high dilution of the reaction mixture is not needed.
authors.affiliation: School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou 213164, P. R. China. jtsun08@gmail.com.
authors.forename: Chenghao
authors.initials: C
authors.lastname: Zhu
authors.forename: Guangyang
authors.initials: G
authors.lastname: Xu
authors.forename: Kai
authors.initials: K
authors.lastname: Liu
authors.forename: Lin
authors.initials: L
authors.lastname: Qiu
authors.forename: Shiyong
authors.initials: S
authors.lastname: Peng
authors.forename: Jiangtao
authors.initials: J
authors.lastname: Sun
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003516:Cycloparaffins / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001391:Azo Compounds; D003516:Cycloparaffins; D006046:Gold