title: Capturing the signal.
abstract: High-resolution structures provide new insights into how an RNA-protein complex recognizes the signal that targets membrane proteins to the endoplasmic reticulum before they aggregate.
authors.affiliation: Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, United States.
authors.forename: Jee-Young
authors.identifier: http://orcid.org/0000-0002-4656-3357
authors.initials: JY
authors.lastname: Mock
authors.affiliation: Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, United States.
authors.forename: William M
authors.identifier: http://orcid.org/0000-0002-0021-889X
authors.initials: WM
authors.lastname: Clemons
mesh_terms: D000818:Animals; D014176:Protein Biosynthesis; D012270:Ribosomes / Q000378:metabolism* / Q000648:ultrastructure*; D018271:Signal Recognition Particle / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D018271:Signal Recognition Particle
keywords: biochemistry; biophysics; cryo-EM; membrane protein biogenesis; protein targeting; rabbit; signal recognition particle; structural biology