title: Treatment resistant somatic delusions in bipolar disorder.
abstract: Two patients each developed a single, fixed somatic delusion complicating their existing bipolar disorder. Both failed to respond to a range of antidepressant and antipsychotic medications. They each showed a partial response to clozapine and to electroconvulsive therapy, with resolution of mood symptoms and diminution of their ongoing somatic preoccupation. A review of case reports suggests a possible relationship between somatic delusions and affective disorders.
authors.affiliation: Flinders Medical Centre, Bedford Park, South Australia, Australia.
authors.forename: Hannah
authors.initials: H
authors.lastname: Slattery
authors.affiliation: Flinders Medical Centre, Bedford Park, South Australia, Australia Department of Psychiatry, Flinders University, Bedford Park, South Australia, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Nance
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000150:complications*; D003024:Clozapine / Q000627:therapeutic use; D003702:Delusions / Q000523:psychology* / Q000628:therapy; D003937:Diagnosis, Differential; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000150:complications / Q000628:therapy; D009059:Mouth Diseases / Q000523:psychology; D012893:Sleep Wake Disorders / Q000523:psychology; D013001:Somatoform Disorders / Q000523:psychology*
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine