title: [Advanced and Metastatic Lung Cancer – What is new in the Diagnosis and Therapy?].
abstract: Lung cancer is one of the most common types of malignancies worldwide. The majority of patients are diagnosed with an incurable advanced/metastatic stage disease. Palliative treatment approaches improve the survival and the quality of life of these patients. Lung cancer is subdivided according to histology and molecular biology. The most important classification separates small cell from non-small cell lung cancer. In the subgroup of non-small cell lung cancer novel treatment approaches coming along with an improved prognosis have been established during the last decade. The current manuscript provides an overview on current treatment options for metastatic lung cancer. Furthermore, an outlook on promising future treatment options is provided.
authors.affiliation: 1 Departement Innere Medizin, Medizinische Onkologie, Universitätsspital Basel.
authors.forename: Sacha I
authors.initials: SI
authors.lastname: Rothschild
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis* / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000175:diagnosis* / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D018450:Disease Progression; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D058990:Molecular Targeted Therapy; D009367:Neoplasm Staging; D010166:Palliative Care; D011379:Prognosis; D016019:Survival Analysis
keywords: Bronchialkarzinom; Chemotherapie; cancer du poumon; cancer du poumon non à petites cellules; cancer du poumon à petites cellules; chemotherapy; chimiothérapie; kleinzelliges Bronchialkarzinom; lung cancer; nicht-kleinzelliges Bronchialkarzinom; non-small cell lung cancer; small cell lung cancer; targeted therapy; traitement personnalisé; zielgerichtete Therapie