title: Relationship between hyperuricemia and dietary risk factors in Chinese adults: a cross-sectional study.
abstract: Previous studies focusing on identification of dietary risk factors for hyperuricemia reported controversial findings. Moreover, evidence for relationship between hyperuricemia and eating and cooking habits remained scanty. The purpose of this study was to evaluate the associations between hyperuricemia and dietary risk factors. A cross-sectional study was conducted among 1583 participants in a Beijing community. Face-to-face interviews were conducted using questionnaires. Anthropometric measurements and biochemical tests were also performed. The prevalence of hyperuricemia was 14.1 % (20.2 % for males and 7.4 % for females). Among the 1372 subjects included for analysis, 720 (52.5 %) were males and the mean age was 37.7 years. For males, statistically significant associations between hyperuricemia and tea intake, breakfast and midnight snack consumption were found, with an odds ratio of 0.56 (high vs. low), 2.14 (often vs. always) and 0.52 (rarely vs. always), respectively. Smoking, fatty liver disease, triglyceride, low-density lipoprotein cholesterol and fasting blood glucose were significantly related to increased serum uric acid (SUA), with a coefficient of 20.06, 11.52, 7.29, 18.97 and 13.37 on SUA, respectively. For females, no statistically significant associations between hyperuricemia and dietary risk factors were observed. In summary, hyperuricemia is highly prevalent among the adult participants in this Chinese community, especially for men. High tea intake and consuming midnight snack rarely are significantly related to decreased risk of hyperuricemia, while often-eating breakfast is associated with increased risk of hyperuricemia compared with always-eating breakfast in males. Further prospective studies are needed to confirm the findings and to establish dietary recommendations for the prevention and treatment of hyperuricemia.
authors.affiliation: Center for Population Health Science, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK.
authors.forename: Xue
authors.initials: X
authors.lastname: Li
authors.affiliation: School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China.
authors.forename: Peige
authors.initials: P
authors.lastname: Song
authors.affiliation: Department of Clinical Medicine, Xingtai Medical College, 618 Gangtie Road, Xingtai, 054000, Hebei, China.
authors.forename: Junping
authors.initials: J
authors.lastname: Li
authors.affiliation: School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China.
authors.forename: Peiyu
authors.initials: P
authors.lastname: Wang
authors.affiliation: Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada. lig28@mcmaster.ca.
authors.forename: Guowei
authors.initials: G
authors.lastname: Li
mesh_terms: D000328:Adult; D000068476:Beijing; D001786:Blood Glucose; D003430:Cross-Sectional Studies; D004032:Diet; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D033461:Hyperuricemia / Q000097:blood / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood*
chemical_list: D001786:Blood Glucose; D014280:Triglycerides; D014527:Uric Acid
keywords: Cooking styles; Eating habits; Food frequency questionnaire; Hyperuricemia; Risk factor