title: Audio-visual integration through the parallel visual pathways.
abstract: Audio-visual integration has been shown to be present in a wide range of different conditions, some of which are processed through the dorsal, and others through the ventral visual pathway. Whereas neuroimaging studies have revealed integration-related activity in the brain, there has been no imaging study of the possible role of segregated visual streams in audio-visual integration. We set out to determine how the different visual pathways participate in this communication. We investigated how audio-visual integration can be supported through the dorsal and ventral visual pathways during the double flash illusion. Low-contrast and chromatic isoluminant stimuli were used to drive preferably the dorsal and ventral pathways, respectively. In order to identify the anatomical substrates of the audio-visual interaction in the two conditions, the psychophysical results were correlated with the white matter integrity as measured by diffusion tensor imaging.The psychophysiological data revealed a robust double flash illusion in both conditions. A correlation between the psychophysical results and local fractional anisotropy was found in the occipito-parietal white matter in the low-contrast condition, while a similar correlation was found in the infero-temporal white matter in the chromatic isoluminant condition. Our results indicate that both of the parallel visual pathways may play a role in the audio-visual interaction.
authors.affiliation: Department of Physiology, University of Szeged, Szeged, Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Kaposvári
authors.affiliation: Department of Physiology, University of Szeged, Szeged, Hungary; Department of Neurology, Albert Szent-Györgyi Clinical Centre, University of Szeged, Szeged, Hungary.
authors.forename: Gergő
authors.initials: G
authors.lastname: Csete
authors.affiliation: Department of Physiology, University of Szeged, Szeged, Hungary.
authors.forename: Anna
authors.initials: A
authors.lastname: Bognár
authors.affiliation: Department of Physiology, University of Szeged, Szeged, Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Csibri
authors.affiliation: Department of Neurology, Albert Szent-Györgyi Clinical Centre, University of Szeged, Szeged, Hungary.
authors.forename: Eszter
authors.initials: E
authors.lastname: Tóth
authors.affiliation: Department of Neurology, Albert Szent-Györgyi Clinical Centre, University of Szeged, Szeged, Hungary; International Clinical Research Centre, St. Anne׳s University Hospital Brno, Brno, Czech Republic.
authors.forename: Nikoletta
authors.initials: N
authors.lastname: Szabó
authors.affiliation: Department of Neurology, Albert Szent-Györgyi Clinical Centre, University of Szeged, Szeged, Hungary; MTA-SZTE Neuroscience Research Group, University of Szeged, Hungary.
authors.forename: László
authors.initials: L
authors.lastname: Vécsei
authors.affiliation: Department of Physiology, University of Szeged, Szeged, Hungary. Electronic address: sary.gyula@med.u-szeged.hu.
authors.forename: Gyula
authors.initials: G
authors.lastname: Sáry
authors.affiliation: Department of Neurology, Albert Szent-Györgyi Clinical Centre, University of Szeged, Szeged, Hungary; International Clinical Research Centre, St. Anne׳s University Hospital Brno, Brno, Czech Republic.
authors.forename: Zsigmond
authors.initials: Z
authors.lastname: Tamás Kincses
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D016880:Anisotropy; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D056324:Diffusion Tensor Imaging; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D010775:Photic Stimulation; D017603:Signal Detection, Psychological / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*; D066127:White Matter / Q000502:physiology*
keywords: DTI; Doubleflash; MRI; Multisensory; TBSS