title: Managing premature menopause and sexual dysfunction.
abstract: OBJECTIVE
  Young women (<45 years of age) diagnosed with breast cancer face increased risk of sexual dysfunction as a result of their cancer-directed treatment. We will review the recent literature examining this critical challenge and discuss current efforts to address sexual dysfunction.
  
  
  RESULTS
  In the period since 2013, the literature has focused on sexual issues that result from the premature onset of menopausal symptoms and changes in sexual health following breast surgery. The impact of premature menopause in young women with breast cancer is profound and can affect all aspects of the sexual experience, from desire to function, and quality of life. Furthermore, the surgical treatment of breast cancer also has significant implications with respect to sexual desire and body image. There is a paucity of sexual health intervention for this population, though recent efforts suggest that sexual health outcomes may be improved if women are offered the appropriate intervention opportunities. However, the sexual function of young breast cancer patients is an under-discussed and under-treated health issue that warrants greater research and clinical focus.
  
  
  CONCLUSIONS
  Further intervention trials must be completed in this population of young women for whom sexual function plays such a critical role in their personal and relationship well being.
authors.affiliation: aDana-Farber Cancer Institute bHarvard Medical School, Boston, MA, USA.
authors.forename: Eric S
authors.initials: ES
authors.lastname: Zhou
authors.forename: Sandy J
authors.initials: SJ
authors.lastname: Falk
authors.forename: Sharon L
authors.initials: SL
authors.lastname: Bober
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001828:Body Image; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000523:psychology / Q000601:surgery; D003142:Communication; D004965:Estrogen Antagonists / Q000009:adverse effects; D005260:Female; D006801:Humans; D007989:Libido / Q000187:drug effects*; D008408:Mastectomy / Q000523:psychology; D008594:Menopause, Premature / Q000187:drug effects*; D010353:Patient Education as Topic; D011788:Quality of Life
chemical_list: D000970:Antineoplastic Agents; D004965:Estrogen Antagonists