title: Nanofibrillated Cellulose and Copper Nanoparticles Embedded in Polyvinyl Alcohol Films for Antimicrobial Applications.
abstract: Our long-term goal is to develop a hybrid cellulose-copper nanoparticle material as a functional nanofiller to be incorporated in thermoplastic resins for efficiently improving their antimicrobial properties. In this study, copper nanoparticles were first synthesized through chemical reduction of cupric ions on TEMPO nanofibrillated cellulose (TNFC) template using borohydride as a copper reducing agent. The resulting hybrid material was embedded into a polyvinyl alcohol (PVA) matrix using a solvent casting method. The morphology of TNFC-copper nanoparticles was analyzed by transmission electron microscopy (TEM); spherical copper nanoparticles with average size of 9.2 ± 2.0 nm were determined. Thermogravimetric analysis and antimicrobial performance of the films were evaluated. Slight variations in thermal properties between the nanocomposite films and PVA resin were observed. Antimicrobial analysis demonstrated that one-week exposure of nonpathogenic Escherichia coli DH5α to the nanocomposite films results in up to 5-log microbial reduction.
authors.affiliation: Division of Forestry and Natural Resources, West Virginia University, Morgantown, WV 26506, USA.
authors.forename: Tuhua
authors.initials: T
authors.lastname: Zhong
authors.affiliation: Division of Forestry and Natural Resources, West Virginia University, Morgantown, WV 26506, USA.
authors.forename: Gloria S
authors.initials: GS
authors.lastname: Oporto
authors.affiliation: Division of Animal and Nutritional Sciences, West Virginia University, Morgantown, WV 26506, USA.
authors.forename: Jacek
authors.initials: J
authors.lastname: Jaczynski
authors.affiliation: Division of Forestry and Natural Resources, West Virginia University, Morgantown, WV 26506, USA.
authors.forename: Changle
authors.initials: C
authors.lastname: Jiang
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000737:chemistry; D002482:Cellulose / Q000008:administration & dosage* / Q000737:chemistry; D003300:Copper / Q000008:administration & dosage / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D011142:Polyvinyl Alcohol / Q000737:chemistry; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D003300:Copper; D011142:Polyvinyl Alcohol; D002482:Cellulose