title: [Study on chemical constituents of Inula cappa].
abstract: Column chromatographies over silica gel, Sephadex LH-20, reverse phase C18, and MCI, and semi-preparative HPLC were used for separation and purification of constituents from Inula cappa. The 22 compounds were obtained and their strutures were determined by NMR and MS spectra data as nine flavonoids: luteolin (1), apigenin (2), chrysoeriol (3), artemetin (4), 2', 5-di- hydroxy-3, 6, 7, 4', 5'-pentamethoxyflavone (5), chrysosplenol C (6), apigenin-5-0-β-D-glucopyranoside (7), luteolin-3-methyl, luteolin-3-methylether-4'-0-β-D-glucopyranoside (8), luteolin-4'-0-β-D-glucopyranoside (9); four triterpenes: darma-20, 24-dien- 3β-0-acetate (10), darma-20, 24-dien-3β-ol (11), epirfiedelanol (12), friedelin (13); three coumarins: scopoletin (14) , isosco- poletin (15) , scopolin(16) , and other types of compounds stigmasta-5, 22-dien-3β-0-7-one (17), stigmasterol (18), palmitic acid (19), linoleic acid (20), linoleic acid methyl ester (21), (E) -9, 12, 13-trihydroxyoetadee-10-enoie acid (22). Compound 5 is a new natural product. Compounds 3-9, 15, 17, 21, and 22 were isolated from this genus for the first time.
authors.forename: Li-hua
authors.initials: LH
authors.lastname: Zheng
authors.forename: Xiao-jiang
authors.initials: XJ
authors.lastname: Hao
authors.forename: Chun-mao
authors.initials: CM
authors.lastname: Yuan
authors.forename: Lie-jun
authors.initials: LJ
authors.lastname: Huang
authors.forename: Jian-xin
authors.initials: JX
authors.lastname: Zhang
authors.forename: Fen
authors.initials: F
authors.lastname: Dong
authors.forename: Tian-yun
authors.initials: TY
authors.lastname: Fan
authors.forename: Gui-hui
authors.initials: GH
authors.lastname: Wu
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.forename: Yuan
authors.initials: Y
authors.lastname: Ma
authors.forename: Yi-min
authors.initials: YM
authors.lastname: Fan
authors.forename: Wei
authors.initials: W
authors.lastname: Gu
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D038143:Inula / Q000737:chemistry*; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D004365:Drugs, Chinese Herbal