title: Burden of Breast Cancer in Iranian Women is Increasing.
abstract: BACKGROUND
  Breast cancer (BC) is the leading cause of oncological death for women, in both developed and developing countries. In Iran, breast cancer ranks first among cancers diagnosed in women. The aim of this study was to present the burden of this cancer including incidence, mortality and years life lost (YLL) due to breast cancer in Iranian women.
  
  
  METHODS
  National incidence data from the Iranian annual National Cancer Registration reports from 2003 to 2009 and national death statistics reported by the Ministry of Health and Medical Education from 1995 to 2010, stratified by age group, were included in this analysis. Also calculated YLLs provided by the Institute for Health Metrics and Evaluation (IHME) for the years 1990, 1995, 2000, 2005 and 2010 were employed to express the years lost due to BC for Iranian women.
  
  
  RESULTS
  The general mortality rate of breast cancer increased during these years from 0.96 to 4.33 per 100,000 and incidence increased from 16.0 to 28.3 per 100,000 for the years under study. YLLs calculated by IHME showed both increasing and decreasing patterns, with a tendency for stabilization.
  
  
  CONCLUSIONS
  The burden of breast cancer for Iranian women is still increasing. Thus, health education programs to inform women regarding the signs and risk factors, and national screening to facilitate early diagnosis are needed for the female community in Iran.
authors.affiliation: Gandy General Hospital, Tehran, Iran E-mail : Aminphg@gmail.com.
authors.forename: Abdolhamid
authors.initials: A
authors.lastname: Sharifian
authors.forename: Mohamad Amin
authors.initials: MA
authors.lastname: Pourhoseingholi
authors.forename: Majid
authors.initials: M
authors.lastname: Emadedin
authors.forename: Mohammad
authors.initials: M
authors.lastname: Rostami Nejad
authors.forename: Sara
authors.initials: S
authors.lastname: Ashtari
authors.forename: Nastaran
authors.initials: N
authors.lastname: Hajizadeh
authors.forename: Seyed Alireza
authors.initials: SA
authors.lastname: Firouzei
authors.forename: Seyed Jalil
authors.initials: SJ
authors.lastname: Hosseini
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008875:Middle Aged; D009026:Mortality / Q000639:trends*; D011379:Prognosis; D012042:Registries; D012307:Risk Factors; D015996:Survival Rate; D013997:Time Factors; D055815:Young Adult