title: Differences in the Pattern of Hemodynamic Response to Self-Face and Stranger-Face Images in Adolescents with Anorexia Nervosa: A Near-Infrared Spectroscopic Study.
abstract: There have been no reports concerning the self-face perception in patients with anorexia nervosa (AN). The purpose of this study was to compare the neuronal correlates of viewing self-face images (i.e. images of familiar face) and stranger-face images (i.e. images of an unfamiliar face) in female adolescents with and without AN. We used near-infrared spectroscopy (NIRS) to measure hemodynamic responses while the participants viewed full-color photographs of self-face and stranger-face. Fifteen females with AN (mean age, 13.8 years) and 15 age- and intelligence quotient (IQ)-matched female controls without AN (mean age, 13.1 years) participated in the study. The responses to photographs were compared with the baseline activation (response to white uniform blank). In the AN group, the concentration of oxygenated hemoglobin (oxy-Hb) significantly increased in the right temporal area during the presentation of both the self-face and stranger-face images compared with the baseline level. In contrast, in the control group, the concentration of oxy-Hb significantly increased in the right temporal area only during the presentation of the self-face image. To our knowledge the present study is the first report to assess brain activities during self-face and stranger-face perception among female adolescents with AN. There were different patterns of brain activation in response to the sight of the self-face and stranger-face images in female adolescents with AN and controls.
authors.affiliation: Department of pediatrics, center for child development and psychosomatic, Dokkyo medical university Koshigaya hospital, Koshigaya, Saitama, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Inoue
authors.affiliation: Faculty of Human Life Sciences, Jissen Women's University, Hino, Tokyo, Japan.
authors.forename: Yuiko
authors.initials: Y
authors.lastname: Sakuta
authors.affiliation: Department of pediatrics, center for child development and psychosomatic, Dokkyo medical university Koshigaya hospital, Koshigaya, Saitama, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Shimamura
authors.affiliation: Faculty of Science and Technology, Tokyo University of Science, Noda, Chiba, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Ichikawa
authors.affiliation: Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Aichi, Japan.
authors.forename: Megumi
authors.initials: M
authors.lastname: Kobayashi
authors.affiliation: Department of pediatrics, center for child development and psychosomatic, Dokkyo medical university Koshigaya hospital, Koshigaya, Saitama, Japan.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Otani
authors.affiliation: Department of Psychology, Chuo University, Hachioji, Tokyo, Japan.
authors.forename: Masami K
authors.initials: MK
authors.lastname: Yamaguchi
authors.affiliation: Department of Psychology, Japan Women's University, Kawasaki, Kanagawa, Japan.
authors.forename: So
authors.initials: S
authors.lastname: Kanazawa
authors.affiliation: Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Aichi, Japan.
authors.forename: Ryusuke
authors.initials: R
authors.lastname: Kakigi
authors.affiliation: Department of pediatrics, center for child development and psychosomatic, Dokkyo medical university Koshigaya hospital, Koshigaya, Saitama, Japan.
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Sakuta
mesh_terms: D000293:Adolescent; D000856:Anorexia Nervosa / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging; D005145:Face / Q000502:physiology*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D010108:Oxyhemoglobins / Q000378:metabolism; D010364:Pattern Recognition, Visual; D011859:Radiography; D019265:Spectroscopy, Near-Infrared
chemical_list: D010108:Oxyhemoglobins