title: Change in Pain and Quality of Life Among Women Enrolled in a Trial Examining the Use of Narrow Band Imaging During Laparoscopic Surgery for Suspected Endometriosis.
abstract: OBJECTIVE
  To examine whether the addition of narrow band imaging (NBI) to traditional white light imaging during laparoscopic surgery impacts pain and quality of life (QOL) at 3 and 6 months after surgery among women with suspected endometriosis and/or infertility.
  
  
  METHODS
  A randomized controlled trial (Canadian Task Force classification level I).
  
  
  METHODS
  The trial was conducted in 2 medical centers.
  
  
  METHODS
  From October 2011 to November 2013, 167 patients undergoing laparoscopic examination for suspected endometriosis and/or infertility were recruited. The analytic study sample includes 148 patients with pain and QOL outcome data.
  
  
  METHODS
  Patients were randomized in a 3:1 ratio to receive white light imaging followed by NBI (WL/NBI) or white light imaging only (WL/WL).
  
  
  RESULTS
  Questionnaires were administered at baseline and at 3- and 6-month follow-up time points. Average and most severe pain at each time point were assessed using a 10-cm visual analog scale. QOL was measured using the Endometriosis Health Profile-30. Baseline characteristics were similar for the study groups. The WL/NBI and WL/WL groups had similar reductions in pain at 3 and 6 months. In addition, QOL improved similarly for both the WL/NBI and WL/WL groups at 3 and 6 months.
  
  
  CONCLUSIONS
  Laparoscopic surgery for suspected endometriosis is associated with a reduction in pain and an improvement in QOL. The differences in pain reduction and QOL improvement, which are noted at 3 months and remain stable at 6 months after surgery, are similar for those undergoing surgery with WL/NBI compared with those undergoing surgery under traditional white light conditions.
authors.affiliation: Mercy Medical Center, Baltimore, Maryland; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland. Electronic address: lisagallicchio@gmail.com.
authors.forename: Lisa
authors.initials: L
authors.lastname: Gallicchio
authors.affiliation: Mercy Medical Center, Baltimore, Maryland; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland.
authors.forename: Kathy J
authors.initials: KJ
authors.lastname: Helzlsouer
authors.affiliation: Mercy Medical Center, Baltimore, Maryland.
authors.forename: Kevin M
authors.initials: KM
authors.lastname: Audlin
authors.affiliation: Advocate Lutheran General Hospital, Park Ridge, Illinois; Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois.
authors.forename: Charles
authors.initials: C
authors.lastname: Miller
authors.affiliation: Mercy Medical Center, Baltimore, Maryland.
authors.forename: Ryan
authors.initials: R
authors.lastname: MacDonald
authors.affiliation: Advocate Lutheran General Hospital, Park Ridge, Illinois.
authors.forename: Mary
authors.initials: M
authors.lastname: Johnston
authors.affiliation: Mercy Medical Center, Baltimore, Maryland.
authors.forename: Fermin F
authors.initials: FF
authors.lastname: Barrueto
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000150:complications* / Q000523:psychology / Q000601:surgery; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology* / Q000523:psychology / Q000601:surgery; D010535:Laparoscopy; D008875:Middle Aged; D062048:Narrow Band Imaging; D010146:Pain / Q000209:etiology* / Q000523:psychology / Q000601:surgery; D010147:Pain Measurement; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
keywords: Endometriosis; Laparoscopy; Narrow band imaging; Pain; Quality of life