title: Chronic Cough.
abstract: Chronic cough (CC), or cough lasting more than 8 weeks, has attracted increased attention in recent years following advances that have changed opinions on the prevailing diagnostic and therapeutic triad in place since the 1970s. Suboptimal treatment results in two thirds of all cases, together with a new notion of CC as a peripheral and central hypersensitivity syndrome similar to chronic pain, have changed the approach to this common complaint in routine clinical practice. The peripheral receptors involved in CC are still a part of the diagnostic triad. However, both convergence of stimuli and central nervous system hypersensitivity are key factors in treatment success.
authors.affiliation: Servicio de Neumología, Hospital Ramón y Cajal, Madrid, España. Electronic address: apacheco.hrc@salud.madrid.org.
authors.forename: Adalberto
authors.initials: A
authors.lastname: Pacheco
authors.affiliation: Servicio de Neumología, Hospital La Fe, Valencia, España.
authors.forename: Alfredo
authors.initials: A
authors.lastname: de Diego
authors.affiliation: Servicio de Neumología, Hospital Parc Taulí, Sabadell, Barcelona, España.
authors.forename: Christian
authors.initials: C
authors.lastname: Domingo
authors.affiliation: Servicio de Pediatría, Hospital Ramón y Cajal, Madrid, España.
authors.forename: Adelaida
authors.initials: A
authors.lastname: Lamas
authors.affiliation: Servicio de Otorrinolaringología, Hospital Rey Juan Carlos, Móstoles, Madrid, España.
authors.forename: Raimundo
authors.initials: R
authors.lastname: Gutierrez
authors.affiliation: Centro de Salud Belchite, Zaragoza, España.
authors.forename: Karlos
authors.initials: K
authors.lastname: Naberan
authors.affiliation: Servicio de Gastroenterología, Hospital La Fe, Valencia, España.
authors.forename: Vicente
authors.initials: V
authors.lastname: Garrigues
authors.affiliation: Servicio de Neumología, Hospital Severo Ochoa, Madrid, España.
authors.forename: Raquel
authors.initials: R
authors.lastname: López Vime
mesh_terms: D018926:Anti-Allergic Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000996:Antitussive Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003371:Cough / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D003948:Diagnostic Techniques, Respiratory System; D019468:Disease Management; D005764:Gastroesophageal Reflux / Q000150:complications / Q000188:drug therapy; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D006801:Humans; D009434:Neural Pathways / Q000503:physiopathology; D011602:Psychophysiologic Disorders / Q000150:complications / Q000188:drug therapy; D011619:Psychotropic Drugs / Q000627:therapeutic use; D012130:Respiratory Hypersensitivity / Q000150:complications / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000150:complications / Q000188:drug therapy; D012891:Sleep Apnea Syndromes / Q000150:complications; D035703:Therapies, Investigational
chemical_list: D018926:Anti-Allergic Agents; D000890:Anti-Infective Agents; D000996:Antitussive Agents; D005765:Gastrointestinal Agents; D011619:Psychotropic Drugs
keywords: Agentes antitusivos; Antittusive agents; Aspiración respiratoria; Cough; Disfunción de cuerdas vocales; Gastroesophageal reflux; Reflujo gastroesofágico; Respiratory aspiration; Tos; Vocal cord dysfunction