title: Development of a Persian Version of the Adult Strabismus Questionnaire and Evaluating the Effect of Strabismus Surgery on Health-Related Quality of Life.
abstract: OBJECTIVE
  To develop a Persian version of the Adult Strabismus Questionnaire (AS-20) and use the new questionnaire to evaluate the effect of strabismus surgery on health-related quality of life (HRQOL).
  
  
  METHODS
  The Persian version of the AS-20 was developed with the help of Beaton and colleagues' guidelines. The reliability of the final version was tested with the test-retest and internal consistency methods. The construct and criterion (concurrent) validity were also tested for the questionnaire. Then, 112 patients with strabismus completed the questionnaire 1 week before and 3 months after strabismus surgery.
  
  
  RESULTS
  The Persian version showed high reliability and validity. The patients with preoperative diplopia had significantly poorer median preoperative total and functional scores than the patients without preoperative diplopia (p=0.04 and 0.009, respectively). In the cases with and without diplopia, the median total, psychosocial, and functional postoperative scores were significantly better than preoperative scores (p=0.01, 0.01, and 0.028, respectively, in diplopic cases, and p<0.0001 for all scores in non-diplopic cases). The females had significantly poorer median preoperative total, psychosocial, and functional scores (p=0.001, 0.02, and 0.0001, respectively) and more postoperative total, psychosocial, and functional score improvement than males (p=0.004, 0.003, and 0.03, respectively).
  
  
  CONCLUSIONS
  Our version might be appropriate for evaluating HRQOL of the patients with strabismus. The significant increase in the total and subscale scores after strabismus surgery showed the importance of strabismus surgery in improving HRQOL of the patients, especially in psychosocial aspects. The strabismus surgery might have a greater benefit in improving HRQOL of the female patients.
authors.affiliation: Farabi Eye Research Center, Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Akbari
authors.forename: Babak
authors.initials: B
authors.lastname: Masoomian
authors.forename: Ahmad
authors.initials: A
authors.lastname: Ameri
authors.forename: Alireza
authors.initials: A
authors.lastname: Keshtkar Jaafari
authors.forename: Arash
authors.initials: A
authors.lastname: Mirmohammadsadeghi
mesh_terms: D000293:Adolescent; D000328:Adult; D004172:Diplopia / Q000523:psychology; D005260:Female; D006304:Health Status; D006801:Humans; D007492:Iran; D008297:Male; D009801:Oculomotor Muscles / Q000601:surgery; D013508:Ophthalmologic Surgical Procedures; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D018434:Sickness Impact Profile; D013285:Strabismus / Q000523:psychology* / Q000601:surgery*; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: AS-20; Adult Strabismus Questionnaire; health-related quality of life; strabismus surgery