title: Role of Esmolol in Perioperative Analgesia and Anesthesia: A Literature Review.
abstract: Use of opioids to provide adequate perioperative analgesia often leads to respiratory depression, nausea, vomiting, urinary retention, pruritus, and opioid-induced hyperalgesia, with the potential to increase length of stay in the hospital. In an effort to reduce perioperative opioid administration yet provide appropriate pain relief, researchers began to study the use of esmolol beyond its well-known cardiovascular effects. Perioperative esmolol has been shown to reduce anesthetic requirements, decrease perioperative opioid use, decrease the incidence of postoperative nausea and vomiting, lead to an earlier discharge, and increase patient satisfaction. This article provides a review of the literature on the use of esmolol as an adjunct for perioperative analgesia and anesthesia.
authors.forename: Megan
authors.initials: M
authors.lastname: Harless
authors.forename: Caleb
authors.initials: C
authors.lastname: Depp
authors.forename: Shawn
authors.initials: S
authors.lastname: Collins
authors.forename: Ian
authors.initials: I
authors.lastname: Hewer
mesh_terms: D058671:Adrenergic beta-1 Receptor Antagonists / Q000008:administration & dosage*; D000698:Analgesia / Q000379:methods; D000700:Analgesics / Q000008:administration & dosage* / Q000009:adverse effects; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000009:adverse effects; D000758:Anesthesia / Q000379:methods*; D000776:Anesthesiology; D005260:Female; D006801:Humans; D008297:Male; D010146:Pain / Q000188:drug therapy*; D059408:Pain Management / Q000379:methods; D010149:Postoperative Pain / Q000517:prevention & control; D059035:Perioperative Period / Q000379:methods*; D020250:Postoperative Nausea and Vomiting / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology; D011412:Propanolamines / Q000008:administration & dosage*
chemical_list: D058671:Adrenergic beta-1 Receptor Antagonists; D000700:Analgesics; D000701:Analgesics, Opioid; D011412:Propanolamines; C036604:esmolol