title: Diagnosis and Management of Twin-Twin Transfusion Syndrome.
abstract: Twin-twin transfusion syndrome (TTTS) affects 10% to 15% of monochorionic pregnancies. In the absences of timely diagnosis and intervention perinatal loss or long term developmental delay can be expected in over 90% of cases. Establishing chorionicity in the first trimester followed by serial ultrasounds beginning at 16 weeks of gestation and intervention with placental laser ablation before the development of advance disease overall survival rates can be expected in 70% to 80% of cases.
authors.affiliation: *Departments of Obstetrics, Gynecology and Reproductive Sciences, and Pediatric Surgery, University of Texas Health Science Center †The Fetal Center at Children's Memorial Hermann Hospital, Houston, Texas.
authors.forename: Anthony
authors.initials: A
authors.lastname: Johnson
mesh_terms: D000740:Anemia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D001163:Arteriovenous Anastomosis; D005260:Female; D046128:Fetal Therapies; D005330:Fetofetal Transfusion / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D053685:Laser Therapy; D010920:Placenta / Q000601:surgery*; D011086:Polycythemia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011247:Pregnancy; D059285:Pregnancy, Twin; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D014471:Umbilical Veins / Q000000981:diagnostic imaging