title: Hemostatic Powders in Gastrointestinal Bleeding: A Systematic Review.
abstract: Topical hemostatic agents and powders are an emerging modality in the endoscopic management of upper and lower gastrointestinal bleeding. This systematic review demonstrates the effectiveness and safety of these agents with special emphasis on TC-325 and Ankaferd Blood Stopper. The unique noncontact/nontraumatic application, ability to cover large areas of bleed, and ease of use make these hemostatic agents an attractive option in certain clinical situations, such as massive bleeding with poor visualization, salvage therapy, and diffuse bleeding from luminal malignancies.
authors.affiliation: Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada.
authors.forename: Yen-I
authors.initials: YI
authors.lastname: Chen
authors.affiliation: Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada; Epidemiology and Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada. Electronic address: alan.barkun@muhc.mcgill.ca.
authors.forename: Alan N
authors.initials: AN
authors.lastname: Barkun
mesh_terms: D000287:Administration, Topical; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy*; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D011208:Powders
chemical_list: D006490:Hemostatics; D011208:Powders
keywords: Ankaferd Blood Stopper; Gastrointestinal bleeding; Hemostatic powders