title: Prediction of motor outcomes and activities of daily living function using diffusion tensor tractography in acute hemiparetic stroke patients.
abstract: [Purpose] The efficacy of diffusion tensor imaging in the prediction of motor outcomes and activities of daily living function remains unclear. We evaluated the most appropriate diffusion tensor parameters and methodology to determine whether the region of interest- or tractography-based method was more useful for predicting motor outcomes and activities of daily living function in stroke patients. [Subjects and Methods] Diffusion tensor imaging data within 10 days after stroke onset were collected and analyzed for 25 patients. The corticospinal tract was analyzed. Fractional anisotropy, number of fibers, and apparent diffusion coefficient were used as diffusion tensor parameters. Motor outcomes and activities of daily living function were evaluated on the same day as diffusion tensor imaging and at 1 month post-onset. [Results] The fractional anisotropy value of the affected corticospinal tract significantly correlated with the motor outcome and activities of daily living function within 10 days post-onset and at 1 month post-onset. Tthere were no significant correlations between other diffusion tensor parameters and motor outcomes or activities of daily living function. [Conclusion] The fractional anisotropy value of the affected corticospinal tract obtained using the tractography-based method was useful for predicting motor outcomes and activities of daily living function in stroke patients.
authors.affiliation: Department of Rehabilitation, Araki Neurosurgical Hospital: 2-8-7 Kogokita, Hiroshima, Hiroshima, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Imura
authors.affiliation: Department of Rehabilitation, Araki Neurosurgical Hospital: 2-8-7 Kogokita, Hiroshima, Hiroshima, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Nagasawa
authors.affiliation: Department of Neurosurgery, Araki Neurosurgical Hospital, Japan.
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Inagawa
authors.affiliation: Department of Rehabilitation, Araki Neurosurgical Hospital: 2-8-7 Kogokita, Hiroshima, Hiroshima, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Imada
authors.affiliation: Department of Radiology, Araki Neurosurgical Hospital, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Izumi
authors.affiliation: Department of Neurosurgery, Araki Neurosurgical Hospital, Japan.
authors.forename: Katsuya
authors.initials: K
authors.lastname: Emoto
authors.affiliation: Department of Neurosurgery, Araki Neurosurgical Hospital, Japan.
authors.forename: Itaru
authors.initials: I
authors.lastname: Tani
authors.affiliation: Department of Neurosurgery, Araki Neurosurgical Hospital, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamasaki
authors.affiliation: Department of Neurosurgery, Araki Neurosurgical Hospital, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Ota
authors.affiliation: Department of Neurosurgery, Araki Neurosurgical Hospital, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Oki
authors.affiliation: Department of Radiology, Araki Neurosurgical Hospital, Japan.
authors.forename: Tadanori
authors.initials: T
authors.lastname: Maeda
authors.affiliation: Department of Neurosurgery, Araki Neurosurgical Hospital, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Araki
keywords: Activities of daily living function; Diffusion tensor tractography; Stroke