title: Risk factors for metastatic osteoarticular infections after a long follow-up of patients with Staphylococcus aureus bacteraemia.
abstract: We aimed to identify risk factors associated with the development of haematogenous metastatic osteoarticular infection (MOI) after an episode of Staphylococcus aureus bacteraemia (SAB). We followed 198 patients with SAB during a median of 68.9 months. Nine (4.54%) developed an MOI (median: 6.77 months) after SAB. Factors associated with MOI were the presence of joint prosthesis (hazard ratio 17.56; 95% CI 4.48-68.85) and osteoporosis (hazard ratio 8.46; 95% CI 1.9-37.57). MOI is a common complication after SAB and is related to high morbidity and mortality. Patients with previous osteoarticular disease are at the greatest risk of developing this complication.
authors.affiliation: Infectious Diseases Unit, Madrid, Spain; Department of Medicine, Faculty of Medicine, Universidad Complutense, Madrid, Spain. Electronic address: lalueza@hotmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Lalueza
authors.affiliation: Infectious Diseases Unit, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Morales-Cartagena
authors.affiliation: Department of Microbiology, Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Chaves
authors.affiliation: Infectious Diseases Unit, Madrid, Spain; Department of Medicine, Faculty of Medicine, Universidad Complutense, Madrid, Spain.
authors.forename: R
authors.initials: R
authors.lastname: San Juan
authors.affiliation: Department of Internal Medicine, University Hospital 12 de Octubre, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Laureiro
authors.affiliation: Infectious Diseases Unit, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Lora-Tamayo
authors.affiliation: Infectious Diseases Unit, Madrid, Spain; Department of Medicine, Faculty of Medicine, Universidad Complutense, Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: López-Medrano
authors.affiliation: Department of Microbiology, Madrid, Spain.
authors.forename: M Á
authors.initials: MÁ
authors.lastname: Orellana
authors.affiliation: Infectious Diseases Unit, Madrid, Spain; Department of Medicine, Faculty of Medicine, Universidad Complutense, Madrid, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Aguado
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000453:epidemiology* / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D013211:Staphylococcus aureus / Q000302:isolation & purification*
keywords: Bacteraemia; Staphylococcus aureus; long-term; metastatic; osteoarticular