title: Blood-brain barrier-associated efflux transporters: a significant but underappreciated obstacle to drug development in glioblastoma.
authors.affiliation: Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario, Canada (W.P.M.).
authors.forename: Warren P
authors.initials: WP
authors.lastname: Mason
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000037:antagonists & inhibitors*; D000818:Animals; D000970:Antineoplastic Agents / Q000493:pharmacokinetics*; D001932:Brain Neoplasms / Q000378:metabolism*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000493:pharmacokinetics*; D005909:Glioblastoma / Q000378:metabolism*; D000081082:Phosphoinositide-3 Kinase Inhibitors; D011743:Pyrimidines / Q000493:pharmacokinetics*; D058570:TOR Serine-Threonine Kinases / Q000037:antagonists & inhibitors*; D013876:Thiophenes / Q000493:pharmacokinetics*
chemical_list: D018528:ATP-Binding Cassette Transporters; D000970:Antineoplastic Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D000081082:Phosphoinositide-3 Kinase Inhibitors; D011743:Pyrimidines; D013876:Thiophenes; D058570:TOR Serine-Threonine Kinases