title: Fucophlorethol C, a phlorotannin as a lipoxygenase inhibitor.
abstract: Fucophlorethol C, a phlorotannin, was isolated from the brown alga Colpomenia bullosa (Scyto-siphonaceae) as a novel lipoxygenase (LOX) inhibitor. It was obtained as a free form from natural origin for the first time. The compound inhibited a soybean LOX to the same extent as the known inhibitor nordihydroguaiaretic acid.
authors.affiliation: a Faculty and Graduate School of Fisheries Sciences , Hokkaido University , Hakodate , Hokkaido 041-8611 , Japan.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kurihara
authors.affiliation: a Faculty and Graduate School of Fisheries Sciences , Hokkaido University , Hakodate , Hokkaido 041-8611 , Japan.
authors.forename: Remi
authors.initials: R
authors.lastname: Konno
authors.affiliation: a Faculty and Graduate School of Fisheries Sciences , Hokkaido University , Hakodate , Hokkaido 041-8611 , Japan.
authors.forename: Koretaro
authors.initials: K
authors.lastname: Takahashi
mesh_terms: D016859:Lipoxygenase Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000459:Phaeophyceae / Q000737:chemistry; D013025:Glycine max / Q000201:enzymology; D013634:Tannins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D016859:Lipoxygenase Inhibitors; D013634:Tannins; C000609951:fucophlorethol C
keywords: Colpomenia bullosa; Fucophlorethol C; Inhibitor; Lipoxygenase; Phlorotannin