title: Arteriovenous malformation within an isocitrate dehydrogenase 1 mutated anaplastic oligodendroglioma.
abstract: BACKGROUND
  The co-occurrence of intracranial arteriovenous malformations (AVMs) and cerebral neoplasms is exceedingly rare but may harbor implications pertaining to the molecular medicine of brain cancer pathogenesis.
  
  
  METHODS
  Here, we present a case of de novo AVM within an isocitrate dehydrogenase 1 mutated anaplastic oligodendroglioma (WHO Grade III) and review the potential contribution of this mutation to aberrant angiogenesis as an interesting case study in molecular medicine.
  
  
  CONCLUSIONS
  The co-occurrence of an IDH1 mutated neoplasm and AVM supports the hypothesis that IDH1 mutations may contribute to aberrant angiogenesis and vascular malformation.
authors.affiliation: School of Medicine, University of California, San Diego, CA, USA.
authors.forename: Grace
authors.initials: G
authors.lastname: Lai
authors.affiliation: Department of Pathology, University of California, San Diego, CA, USA.
authors.forename: Karra A
authors.initials: KA
authors.lastname: Muller
authors.affiliation: Department of Neurosurgery, University of California, San Diego, CA, USA.
authors.forename: Bob S
authors.initials: BS
authors.lastname: Carter
authors.affiliation: Department of Neurosurgery, University of California, San Diego, CA, USA.
authors.forename: Clark C
authors.initials: CC
authors.lastname: Chen
keywords: Arteriovenous malformation; isocitrate dehydrogenase 1; oligodendroglioma