title: Prior cholecystectomy predisposes to acute pancreatitis in codeine-prescribed patients.
abstract: In this paper, we report a case of drug-induced pancreatitis just after taking a pain pill including a low-dose combination of acetaminophen and codeine. Codeine-induced pancreatitis has been rarely reported, however, well-established. The proposed mechanism for codeine-induced pancreatitis is by increasing Oddi sphincter pressure. However, the clinically important point is that the codeine-induced pancreatitis is seen almost only in the cholecystectomized patients due to lacking of its reservoir capacity. Codeine is commonly used alone or in combination in pain medicine. Therefore, it is fairly important to question whether a patient underwent cholecystectomy when a physician decides to prescribe codeine-included preparations.
authors.affiliation: Department of Cardiology, Sanko University School of Medicine, Gaziantep, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Turkmen
authors.affiliation: Department of Internal Medicine, Gaziantep University School of Medicine, Gaziantep, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Buyukhatipoglu
authors.affiliation: Department of Internal Medicine, Gaziantep University School of Medicine, Gaziantep, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Suner
authors.affiliation: Department of Internal Medicine, Necip Fazil Metropolitan Hospital, Kahramanmaras, Turkey.
authors.forename: Haci Gokhan
authors.initials: HG
authors.lastname: Apucu
authors.affiliation: Department of Internal Medicine, Harran University School of Medicine, Sanliurfa, Turkey.
authors.forename: Turgay
authors.initials: T
authors.lastname: Ulas
keywords: Cholecystectomy; codeine; pancreatitis