title: Scaffolds and tissue regeneration: An overview of the functional properties of selected organic tissues.
abstract: Tissue engineering plays a significant role both in the re-establishment of functions and regeneration of organic tissues. Success in manufacturing projects for biological scaffolds, for the purpose of tissue regeneration, is conditioned by the selection of parameters such as the biomaterial, the device architecture, and the specificities of the cells making up the organic tissue to create, in vivo, a microenvironment that preserves and further enhances the proliferation of a specific cell phenotype. To support this approach, we have screened scientific publications that show biomedical applications of scaffolds, biomechanical, morphological, biochemical, and hemodynamic characteristics of the target organic tissues, and the possible interactions between different cell matrices and biological scaffolds. This review article provides an overview on the biomedical application of scaffolds and on the characteristics of the (bio)materials commonly used for manufacturing these biological devices used in tissue engineering, taking into consideration the cellular specificity of the target tissue. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 1483-1494, 2016.
authors.affiliation: LaBNUS-Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba, SP, Brazil.
authors.forename: Márcia A
authors.initials: MA
authors.lastname: Rebelo
authors.affiliation: LaBNUS-Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba, SP, Brazil.
authors.forename: Thais F R
authors.initials: TF
authors.lastname: Alves
authors.affiliation: LaBNUS-Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba, SP, Brazil.
authors.forename: Renata
authors.initials: R
authors.lastname: de Lima
authors.affiliation: LaBNUS-Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba, SP, Brazil.
authors.forename: José M
authors.initials: JM
authors.lastname: Oliveira
authors.affiliation: LaBNUS-Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba, SP, Brazil.
authors.forename: Marta M D C
authors.initials: MM
authors.lastname: Vila
authors.affiliation: LaBNUS-Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba, SP, Brazil.|i(bs)2-Intelligent Biosensing and Biomolecule Stabilization Research Group, University of Sorocaba, Sorocaba, SP, Brazil.|CEB-Centre of Biological Engineering, University of Minho, Braga, Portugal.
authors.forename: Victor M
authors.initials: VM
authors.lastname: Balcão
authors.affiliation: Institute of Technology and Research, University of Tiradentes, Aracaju, SE, Brazil.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Severino
authors.affiliation: LaBNUS-Biomaterials and Nanotechnology Laboratory, University of Sorocaba, Sorocaba, SP, Brazil. marco.chaud@prof.uniso.br.
authors.forename: Marco V
authors.initials: MV
authors.lastname: Chaud
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D005109:Extracellular Matrix / Q000737:chemistry*; D006801:Humans; D012038:Regeneration; D054457:Tissue Scaffolds
keywords: biomaterial; biomimetic platform; quorum sensing; scaffold; tissue regeneration