title: [H. pylori-negative gastric cancer].
abstract: Broad category of H. pylori-negative gastric cancer includes true gastric cancer without history of H. pylori infection, gastric cancer after successful eradication of H. pylori, and H. pylori-negative gastric cancer with history of H. pylori infection. The frequency of gastric cancer without history of H. pylori infection was less than 1% in Japan. Although preventive effect for gastric cancer of H. pylori eradication can be expected, risk of gastric cancer incidence continues after eradication of H. pylori. The frequency of gastric cancer after successful eradication has been increasing, since eradication treatment was widely spread in Japan. The features of H. pylori-negative gastric cancer were reported to be different from conventional H. pylori-positive gastric cancer. Endoscopic screening of gastric cancer requires to understand the characteristics of gastric cancer based on status of H. pylori infection.
authors.forename: Mototsugu
authors.initials: M
authors.lastname: Kato
authors.forename: Shouko
authors.initials: S
authors.lastname: Ono
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Naoya
authors.initials: N
authors.lastname: Sakamoto
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Mabe
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D060740:Disease Eradication; D005260:Female; D016481:Helicobacter Infections; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000453:epidemiology*