title: [COMPARATIVE ASSESSMENT OF THE MULTIMEDIA CANCER HEALTH RISKS CAUSED BY CONTAMINATION OF THE KRASNOIARSK KRAĬ REGIONS' ENVIRONMENT].
abstract: Krasnoyarsk Krai is a region with developed mining and processing industries, notoriously known industries, as sources of carcinogenic emission. For 55 administrative units of the Krai 303 large enterprises' industrial emissions were preliminary prioritized and their location was designated. Only 52% out of the carcinogens emitted into the ambient air by industries were controlled, in other environments the figures ranged from 20% (soil, food) to 48% (drinking water), 10 carcinogens were not controlled in the environment at all. Based on the results of ranking carcinogenic emission and analysis of the carcinogens monitoring in the environment in 2007-2011 31 substances were selected. A comparative analysis of multiple environmental carcinogenic risks showed that 78% of the areas, based on the receipt ofcarcinogensfrom two media, and 80% ofthe areas taking into account the receipt ofcarcinogens from three media attributed to the alarming level of risk for population, that requires continuous monitoring and routine health interventions for its mitigation. The maximal multiple environmental risk values that took into account inputs from all sources were close to the upper boundary alarming level of risk, in Divnogorsk (7,80E-04), Norilsk (7,97 E-04), Krasnoyarsk (8,84E-04) and Achinsk (9,4 E-04). The greatest inputs to total individual cancer risk from polluted ambient air were made by benzene, chromium VI, formaldehyde and nickel, from drinking water--by arsenic, aldrin and heptachlor from soil--by arsenic and lead. The ambient air input into total multiple environmental carcinogenic risk ranged from 31.5 to 99.5%, drinking water input--from 0.5 to 68.5%, soil--up to 0.1%. Areas with maximum levels of total carcinogenic risk are characterized by the highest levels of average long-term indices of cancer development. The study discussed in this article has screening nature. Further in-depth researches for carcinogenic and toxic multimedia risks are required.
authors.forename: S M
authors.initials: SM
authors.lastname: Novikov
authors.forename: T A
authors.initials: TA
authors.lastname: Shashina
authors.forename: N S
authors.initials: NS
authors.lastname: Dodina
authors.forename: V A
authors.initials: VA
authors.lastname: Kislitsin
authors.forename: L M
authors.initials: LM
authors.lastname: Vorobieva
authors.forename: D V
authors.initials: DV
authors.lastname: Goriaev
authors.forename: I V
authors.initials: IV
authors.lastname: Tikhonova
authors.forename: S V
authors.initials: SV
authors.lastname: Kurkatov
mesh_terms: D000397:Air Pollution / Q000032:analysis*; D002274:Carcinogens, Environmental / Q000032:analysis*; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D004784:Environmental Monitoring / Q000379:methods*; D006801:Humans; D015994:Incidence; D009369:Neoplasms / Q000139:chemically induced / Q000453:epidemiology*; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012800:Siberia / Q000453:epidemiology
chemical_list: D002274:Carcinogens, Environmental