title: Non-Hodgkin Lymphoma of the Stomach in a Patient Treated with Natalizumab.
abstract: A 61-year-old man with relapsing-remitting multiple sclerosis developed extranodal large B-cell lymphoma of the stomach following monthly natalizumab infusions for 6 years. Development of lymphoproliferative disorders increases with chronic use of immunosuppression. Cases of primary central nervous system lymphoma as well as one case of peripheral T-cell lymphoma have previously been reported with natalizumab use. Given the absence of a known association between multiple sclerosis and extranodal presentations of diffuse large B-cell lymphoma, a causal association with natalizumab administration cannot be excluded.
authors.affiliation: Division of Hematology-Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ; Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Jennie Y
authors.initials: JY
authors.lastname: Law
authors.affiliation: Division of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ; Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Dong W
authors.initials: DW
authors.lastname: Kim
authors.affiliation: Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Ariel
authors.initials: A
authors.lastname: Sturgis
authors.affiliation: Division of Hematology-Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA. ; Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Harris V
authors.initials: HV
authors.lastname: Naina
keywords: Non-Hodgkin lymphoma of the stomach; multiple sclerosis; natalizumab