title: Squamous cell lung cancer in a male with pulmonary tuberculosis.
abstract: Lung cancer and pulmonary tuberculosis (TB) are highly prevalent and representing major public health issues. They share common risk factors and clinical manifestations. It is also suggested that TB predicts raised lung cancer risk likely related to chronic inflammation in the lungs. However, it does not seem to influence the clinical course of lung cancer provided that it is properly treated. We present a case report of a 57-year old male with concurrent TB and lung cancer. He was diagnosed with positive sputum smear for acid fast bacilli (AFB) and subsequent culture of Mycobacterium tuberculosis. Besides, his comorbid conditions were chronic hepatitis C virus (HCV) infection and peripheral artery disease (PAD). Later while on anti-tuberculous treatment (ATT) squamous cell lung cancer (SCC) was confirmed with computed tomography (CT) guided biopsy. Due to poor general condition the patient was not fit for either surgery or radical chemo- and radiotherapy. He was transferred to hospice for palliative therapy. We want to emphasize that both TB and lung cancer should be actively sought for in patients with either disorder. In addition, there is no doubt that these patients with lung cancer and with good response to TB treatment should be promptly considered for appropriate anticancer therapy.
authors.affiliation: Tuberculosis Ward, Wielkopolska Centre of Pulmonology and Thoracic Surgery, Poznań, Poland. marcinas@gazeta.pl.
authors.forename: Marcin
authors.initials: M
authors.lastname: Skowroński
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Iwanik
authors.forename: Anna
authors.initials: A
authors.lastname: Halicka
authors.forename: Aleksander
authors.initials: A
authors.lastname: Barinow-Wojewódzki
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications* / Q000175:diagnosis; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000382:microbiology; D003937:Diagnosis, Differential; D019698:Hepatitis C, Chronic / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D058729:Peripheral Arterial Disease / Q000150:complications / Q000175:diagnosis; D012307:Risk Factors; D013183:Sputum / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology