title: Catalytic Asymmetric Bromination of Unfunctionalized Olefins with H2O as a Nucleophile.
abstract: The dimeric cinchona alkaloid (DHQD)2 PHAL is used to catalyze an effective asymmetric bromohydroxylation of unfunctionalized olefins with H2 O as nucleophile an N-bromobenzamide as a bromine source. A variety of optically active bromohydrins are formed with up to 88 % ee.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 10090 (P. R. China).
authors.forename: Xun
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 10090 (P. R. China).
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 10090 (P. R. China).
authors.forename: Hua
authors.initials: H
authors.lastname: Tian
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 10090 (P. R. China). Yian.Shi@colostate.edu.|State Key Laboratory of Coordination Chemistry, Center for Multimolecular Organic Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093 (P. R. China). Yian.Shi@colostate.edu.|Department of Chemistry, Colorado State University, Fort Collins, Colorado, 80523 (USA). Yian.Shi@colostate.edu.
authors.forename: Yian
authors.initials: Y
authors.lastname: Shi
keywords: bromination; cinchona alkaloids; enantioselectivity; olefins; water