title: [Curare-Like Camphor Derivatives and Their Biological Activity].
abstract: The synthesis and evaluation of muscle relaxant activity of series of dimeric camphor derivatives are described. Compounds in which the quaternary nitrogen atoms are separated by aromatic chain exhibited the highest efficiency as muscle relaxant. It was shown the screening of a charged atom and counter-ion does not have a significant role on the activity of the studied agents.
authors.forename: A S
authors.initials: AS
authors.lastname: Sokolova
authors.forename: E A
authors.initials: EA
authors.lastname: Morozova
authors.forename: V G
authors.initials: VG
authors.lastname: Vasilev
authors.forename: O I
authors.initials: OI
authors.lastname: Yarovaya
authors.forename: T G
authors.initials: TG
authors.lastname: Tolstikova
authors.forename: N F
authors.initials: NF
authors.lastname: Salakhutdinov
mesh_terms: D000818:Animals; D002164:Camphor / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008297:Male; D051379:Mice; D003473:Neuromuscular Nondepolarizing Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: D003473:Neuromuscular Nondepolarizing Agents; D002164:Camphor