title: Synthesis of intensity gradient and texture information for efficient three-dimensional segmentation of medical volumes.
abstract: We propose a framework that efficiently employs intensity, gradient, and textural features for three-dimensional (3-D) segmentation of medical (MRI/CT) volumes. Our methodology commences by determining the magnitude of intensity variations across the input volume using a 3-D gradient detection scheme. The resultant gradient volume is utilized in a dynamic volume growing/formation process that is initiated in voxel locations with small gradient magnitudes and is concluded at sites with large gradient magnitudes, yielding a map comprising an initial set of partitions (or subvolumes). This partition map is combined with an entropy-based texture descriptor along with intensity and gradient attributes in a multivariate analysis-based volume merging procedure that fuses subvolumes with similar characteristics to yield a final/refined segmentation output. Additionally, a semiautomated version of the aforestated algorithm that allows a user to interactively segment a desired subvolume of interest as opposed to the entire volume is also discussed. Our approach was tested on several MRI and CT datasets and the results show favorable performance in comparison to the state-of-the-art ITK-SNAP technique.
authors.affiliation: Rochester Institute of Technology , Chester F. Carlson Center for Imaging Science, 1 Lomb Memorial Drive, Rochester, New York 14623, United States.
authors.forename: Sreenath Rao
authors.initials: SR
authors.lastname: Vantaram
authors.affiliation: Rochester Institute of Technology , Chester F. Carlson Center for Imaging Science, 1 Lomb Memorial Drive, Rochester, New York 14623, United States ; Rochester Institute of Technology , Department of Electrical and Microelectronic Engineering, 1 Lomb Memorial Drive, Rochester, New York 14623, United States.
authors.forename: Eli
authors.initials: E
authors.lastname: Saber
authors.affiliation: Rochester Institute of Technology , Chester F. Carlson Center for Imaging Science, 1 Lomb Memorial Drive, Rochester, New York 14623, United States ; Rochester Institute of Technology , Department of Electrical and Microelectronic Engineering, 1 Lomb Memorial Drive, Rochester, New York 14623, United States.
authors.forename: Sohail A
authors.initials: SA
authors.lastname: Dianat
authors.affiliation: Rochester Institute of Technology , Chester F. Carlson Center for Imaging Science, 1 Lomb Memorial Drive, Rochester, New York 14623, United States.
authors.forename: Yang
authors.initials: Y
authors.lastname: Hu
keywords: 3-D gradient detection; medical image segmentation; multivariate analysis; volume growing; volumetric segmentation