title: Buchwald-Hartwig Amination of (Hetero)Aryl Tosylates Using a Well-Defined N-Heterocyclic Carbene/Palladium(II) Precatalyst.
abstract: The cross-coupling of aryl tosylates with amines and anilines was achieved by using for the first time a Pd-NHC system based on the popular Pd-PEPPSI precatalyst platform in which the anchoring imidazol-2-ylidene ligand IPr((NMe2)2) incorporates two dimethylamino groups as backbone substituents enhancing both the electronic and steric properties of the carbene. The system optimization and its application scope are disclosed.
authors.affiliation: †CNRS, LCC (laboratoire de Chimie de Coordination), 205 route de Narbonne, F-31077 Toulouse Cedex 4, France.|‡Université de Toulouse, UPS, INPT, 31077 Toulouse, France.
authors.forename: Yin
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: †CNRS, LCC (laboratoire de Chimie de Coordination), 205 route de Narbonne, F-31077 Toulouse Cedex 4, France.|‡Université de Toulouse, UPS, INPT, 31077 Toulouse, France.
authors.forename: Guy
authors.initials: G
authors.lastname: Lavigne
authors.affiliation: †CNRS, LCC (laboratoire de Chimie de Coordination), 205 route de Narbonne, F-31077 Toulouse Cedex 4, France.|‡Université de Toulouse, UPS, INPT, 31077 Toulouse, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: César