title: Choroidal Thickness in Patients with Systemic Lupus Erythematosus Analyzed by Spectral-domain Optical Coherence Tomography.
abstract: OBJECTIVE
  The aim of this study is to investigate the effect of systemic lupus erythematosus (SLE) on choroidal thickness (CT) in the subfoveal and perifoveal area as measured by enhanced depth imaging optical coherence tomography (EDI-OCT) in patients with SLE.
  
  
  METHODS
  Fifty-eight patients with SLE (study group) and 58 healthy individuals (control group) were enrolled in the study. The subfoveal and perifoveal CT were measured by EDI-OCT.
  
  
  RESULTS
  The mean CT (μm) subfoveal, nasal, and temporal was 231.2 ± 57.6, 190.56 ± 30.64, and 222.65 ± 37.45 in the study group and 297.5 ± 45.1, 248.34 ± 39.67, and 286.54 ± 49.65 in the control group, respectively (p < 0.001, for all).
  
  
  CONCLUSIONS
  The mean subfoveal, nasal, and temporal CT values were statistically significantly lower in patients with SLE when compared with healthy controls.
authors.affiliation: a Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Department of Ophthalmology , Ankara , Turkey .
authors.forename: Hasan
authors.initials: H
authors.lastname: Altinkaynak
authors.affiliation: a Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Department of Ophthalmology , Ankara , Turkey .
authors.forename: Necati
authors.initials: N
authors.lastname: Duru
authors.affiliation: a Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Department of Ophthalmology , Ankara , Turkey .
authors.forename: Betül Seher
authors.initials: BS
authors.lastname: Uysal
authors.affiliation: b Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Department of Rheumatology , Ankara , Turkey .
authors.forename: Şükran
authors.initials: Ş
authors.lastname: Erten
authors.affiliation: c Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Department of Ophthalmology , Ankara , Turkey , and.
authors.forename: Piraye Zeynep
authors.initials: PZ
authors.lastname: Kürkcüoğlu
authors.affiliation: c Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Department of Ophthalmology , Ankara , Turkey , and.
authors.forename: Nilay
authors.initials: N
authors.lastname: Yüksel
authors.affiliation: d Ankara Numune Education and Research Hospital, Department of Ophthalmology , Ankara , Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Duru
authors.affiliation: a Yıldırım Beyazıt University, Ankara Atatürk Education and Research Hospital, Department of Ophthalmology , Ankara , Turkey .
authors.forename: Nurullah
authors.initials: N
authors.lastname: Çağıl
mesh_terms: D000328:Adult; D001794:Blood Pressure; D002829:Choroid / Q000000981:diagnostic imaging / Q000473:pathology*; D015862:Choroid Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D041623:Tomography, Optical Coherence; D055815:Young Adult
keywords: Choroidal thickness; choroidopathy; enhanced depth imaging optical coherence tomography; optical coherence tomography; systemic lupus erythematosus