title: Near infrared-caged d-amino acids multifunctional assembly for simultaneously eradicating biofilms and bacteria.
abstract: A nanodevice composed of an upconverting nanoparticle (UCNP) core and a thin TiO2 shell surface modified with d-amino acids was designed. Due to the UCNP core, NIR light can be converted to high-energy UV photons. As a consequence, UV light can stimulate the TiO2 shell to produce antibacterial reactive oxygen species (ROS) and trigger the release of free d-amino acids (antibiofilm agents).
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. xqu@ciac.ac.cn.
authors.forename: Weili
authors.initials: W
authors.lastname: Wei
authors.forename: Wei
authors.initials: W
authors.lastname: Bing
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D001412:Bacillus subtilis / Q000502:physiology; D018441:Biofilms / Q000187:drug effects*; D007259:Infrared Rays; D053768:Metal Nanoparticles / Q000737:chemistry / Q000633:toxicity* / Q000648:ultrastructure; D017382:Reactive Oxygen Species / Q000737:chemistry; D014025:Titanium / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D017382:Reactive Oxygen Species; C009495:titanium dioxide; D014025:Titanium