title: Pregnancy in a woman with pulmonary hypertension: favorable outcome with intravenous treprostinil.
abstract: Pulmonary hypertension (PH) presents a high risk for maternal mortality. The intravenous administration of treprostinil has demonstrated effectiveness for the treatment of PH, though documentations of its use during pregnancy are few. The authors present a 30-year-old gravid women with symptoms of PH at 23 weeks gestation. Treatment comprised of oxygen therapy, enoxaparin, and intravenous treprostinil from gestational week 25, following a successful elective cesarean section at 33 weeks gestation with favorable outcome. This report demonstrates the effectiveness of an intensive therapeutic protocol, including intravenous treprostinil, for the treatment of PH in pregnancy.
authors.forename: D
authors.initials: D
authors.lastname: Rosengarten
authors.forename: R
authors.initials: R
authors.lastname: Kramer
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002585:Cesarean Section; D017984:Enoxaparin / Q000627:therapeutic use*; D011464:Epoprostenol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000628:therapy*; D007262:Infusions, Intravenous; D010102:Oxygen Inhalation Therapy; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000628:therapy*; D011262:Pregnancy Trimester, Second
chemical_list: D000925:Anticoagulants; D000959:Antihypertensive Agents; D017984:Enoxaparin; D011464:Epoprostenol; C427248:treprostinil