title: [Non-Pharmacological Interventions for the Prevention of Weight Gain in Schizophrenic Patients Treated with Antipsychotic Medication].
abstract: OBJECTIVE
  To evaluate the effect of non-pharmacological interventions to prevent anti-psychotic medication induced weight gain in patients with a first episode of schizophrenia.
  
  
  METHODS
  We searched electronic databases Medline, Embase and PsychINFO and reference lists of articles. Controlled trials evaluating the beneficial effects of non-pharmacological interventions to prevent weight gain were eligible for inclusion. Two authors independently assessed the risk of bias of the studies and extracted data.
  
  
  RESULTS
  9 studies met the inclusion criteria. Evaluation of studies was carried out separately according to the different interventions. Six studies examined the effect of behavioral interventions. Two meta-analysis were conducted and found small effects on weight management in favor of the behavioral intervention. Three studies reported the effect of nutritional counselling yielding contradictory results .
  
  
  CONCLUSIONS
  There is currently no clear evidence which intervention is the best to prevent antipsychotic-induced weight gain in patients with first episode of schizophrenia. Further trials of high methodological quality are necessary.
authors.affiliation: Institut für Medizinische Soziologie, Medizinische Fakultät der Martin-Luther-Universität Halle-Wittenberg.
authors.forename: Astrid
authors.initials: A
authors.lastname: Fink
authors.affiliation: Institut für Medizinische Soziologie, Medizinische Fakultät der Martin-Luther-Universität Halle-Wittenberg.
authors.forename: Sandra
authors.initials: S
authors.lastname: Cieslak
authors.affiliation: Institut für Medizinische Soziologie, Medizinische Fakultät der Martin-Luther-Universität Halle-Wittenberg.
authors.forename: Frank
authors.initials: F
authors.lastname: Rosenbach
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001521:Behavior Therapy; D001714:Bipolar Disorder / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D004038:Diet, Reducing; D002149:Energy Intake; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D050177:Overweight / Q000139:chemically induced* / Q000517:prevention & control* / Q000523:psychology; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D012559:Schizophrenia / Q000175:diagnosis / Q000628:therapy*; D012565:Schizophrenic Psychology; D013177:Sports / Q000523:psychology; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D014150:Antipsychotic Agents