title: An Update on the Inflammatory Response after Endovascular Repair for Abdominal Aortic Aneurysm.
abstract: Postimplantation syndrome (PIS) is the clinical and biochemical expression of an inflammatory response following endovascular repair of an aortic aneurysm (EVAR). The goal of this review is to provide an update on the inflammatory response after endovascular repair of abdominal aortic aneurysm, discussing its causes and effects on the clinical outcome of the patient. PIS concerns nearly one-third of patients after EVAR. It is generally a benign condition, although in some patients it may negatively affect outcome. The different definitions and conclusions drawn from several studies reveal that PIS needs to be redefined with standardized diagnostic criteria. The type of the endograft's material seems to play a role in the inflammatory response. Future studies should focus on a better understanding of the underlying pathophysiology, predictors, and risk factors as well as determining whether effective preventive strategies are necessary.
authors.affiliation: Department of Anesthesiology, School of Medicine, University of Ioannina, 45110 Ioannina, Greece.
authors.forename: Eleni
authors.initials: E
authors.lastname: Arnaoutoglou
authors.affiliation: Department of Surgery, Vascular Surgery Unit, School of Medicine, University of Ioannina, 45110 Ioannina, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Kouvelos
authors.affiliation: First Department of Surgery, Vascular Surgery Division, School of Medicine, University of Athens, 11527 Athens, Greece.
authors.forename: Andreas
authors.initials: A
authors.lastname: Koutsoumpelis
authors.affiliation: First Department of Surgery, Vascular Surgery Division, School of Medicine, University of Athens, 11527 Athens, Greece.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Patelis
authors.affiliation: 3rd Department of Surgery, Vascular Surgery Unit, Medical School, University of Athens, 11527 Athens, Greece.
authors.forename: Andreas
authors.initials: A
authors.lastname: Lazaris
authors.affiliation: Department of Surgery, Vascular Surgery Unit, School of Medicine, University of Ioannina, 45110 Ioannina, Greece.
authors.forename: Miltiadis
authors.initials: M
authors.lastname: Matsagkas
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D002097:C-Reactive Protein / Q000502:physiology; D016207:Cytokines / Q000502:physiology; D057510:Endovascular Procedures / Q000009:adverse effects*; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D011183:Postoperative Complications / Q000209:etiology; D013927:Thrombosis / Q000209:etiology
chemical_list: D016207:Cytokines; D002097:C-Reactive Protein