title: Real-time in vivo micromorphology and histopathology of choroidal osteoma using enhanced depth imaging.
abstract: Choroidal osteoma is a usually unilateral benign tumor of the choroid composed of mature bone. Optical coherence tomography (OCT) has been used to image osteoma for several years. With the advent of enhanced depth imaging (EDI) feature of spectral-domain OCT (SD-OCT), better visualization of the morphology of choroidal lesions has been possible. Herein we present a case of choroidal osteoma in a 45-year-old woman, wherein in vivo morphology of the choroidal osteoma had been visualized using EDI technique of SD-OCT before and after performing photodynamic therapy. EDI OCT has proven to be a valuable noninvasive imaging modality, almost comparable to histopathological examination, for diagnosing choroidal osteomas and for providing an insight into the in vivo micromorphological changes occurring during the course of the disease.
authors.forename: Rameez
authors.initials: R
authors.lastname: Hussain
authors.forename: Giridhar
authors.initials: G
authors.lastname: Anantharaman
authors.affiliation: Department of Vitreoretina, Giridhar Eye Institute, Ponneth Temple Road, Kadavanthara, Kochi, Kerala, India.
authors.forename: Bindu
authors.initials: B
authors.lastname: Rajesh
authors.forename: Mahesh
authors.initials: M
authors.lastname: Gopalakrishnan
mesh_terms: D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary*; D002829:Choroid / Q000473:pathology*; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000556:secondary*; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007089:Image Enhancement; D008875:Middle Aged; D010016:Osteoma / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity