title: Synthesis of new colori/fluorimetric chemosensor for selective sensing of biologically important Fe³⁺, Cu²⁺ and Zn²⁺ metal ions.
abstract: New Schiff base chemosensors (1 and 2) based on aryl ether amine were synthesized and demonstrated positional isomer and functional group dependent colori/fluorimetric sensing of Fe(3+), Cu(2+) and Zn(2+) at ppm level. Methoxy salicylaldehyde based chemosensor 1 exhibited selective colorimetric sensing of Fe(3+) whereas 2-hydroxy naphthaldehyde based chemosensor 2 showed selective disappearance of yellow color for Cu(2+) ions. Interestingly, both 1 and 2 exhibited a highly selective strong turn-on fluorescence for Zn(2+). The significance of COOH group in 1 and 2 for Zn(2+) turn-on fluorescence sensing has been confirmed by structure-property studies. Concentration dependent studies of 1 and 2 indicate that Fe(3+), Cu(2+) and Zn(2+) can be detected up to 10 μM. The formation of 1:1 Zn(2+) and chemosensor (1 and 2) confirmed by NMR studies. High selectivity of 1 and 2 was demonstrated by interference studies in presence of different metal ions.
authors.affiliation: School of Chemical & Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India.
authors.forename: Anu
authors.initials: A
authors.lastname: Kundu
authors.affiliation: School of Chemical & Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India.
authors.forename: P S
authors.initials: PS
authors.lastname: Hariharan
authors.affiliation: School of Chemical & Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India.
authors.forename: K
authors.initials: K
authors.lastname: Prabakaran
authors.affiliation: School of Chemical & Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India. Electronic address: philip@biotech.sastra.edu.
authors.forename: Savarimuthu Philip
authors.initials: SP
authors.lastname: Anthony
mesh_terms: D003124:Colorimetry; D003300:Copper / Q000032:analysis*; D005470:Fluorometry; D007501:Iron / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D012545:Schiff Bases / Q000138:chemical synthesis*; D013050:Spectrometry, Fluorescence; D015032:Zinc / Q000032:analysis*
chemical_list: D012545:Schiff Bases; D003300:Copper; D007501:Iron; D015032:Zinc
keywords: Colorimetric sensor; Cu(2+) sensor; Fe(3+) sensor; Fluorescence sensor; Zn(2+) sensor