title: Medical and oncological management of malignant mesothelioma.
abstract: Mesothelioma is an aggressive cancer, for which no curative oncological treatment currently exists. This article outlines the options for managing malignant pleural effusions, describes the developments in chemotherapy over the past 10 years and summarizes the evidence for prophylactic and palliative radiotherapy.
authors.affiliation: Specialist Registrar in the Department of Respiratory Medicine, Bristol Royal Infirmary, Bristol BS2 8HW.
authors.forename: Anna C
authors.initials: AC
authors.lastname: Bibby
authors.affiliation: Specialist Registrar.
authors.forename: Lara
authors.initials: L
authors.lastname: Gibbs
authors.affiliation: Consultant Medical Oncologist, Bristol Haematology & Oncology Centre, Bristol.
authors.forename: Jeremy P
authors.initials: JP
authors.lastname: Braybrooke
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002408:Catheters, Indwelling; D015505:Chest Tubes; D005493:Folic Acid Antagonists / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D008654:Mesothelioma / Q000188:drug therapy* / Q000532:radiotherapy*; D000086002:Mesothelioma, Malignant; D016066:Pleural Effusion, Malignant / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents; D005493:Folic Acid Antagonists