title: [Invasive Streptococcus pneumoniae infection (Austrian syndrome): a case report].
abstract: Austrian syndrome is defined as the triad consisting of pneumonia, endocarditis and meningitis due to invasive Streptococcus pneumoniae infection. Few case reports have been reported since its first description in 1975 by Robert Austrian, mainly because it is rarely observed. Below we report the case of a 61 year-old male patient who presented with bacterial meningitis due S. pneumoniae followed by bacterial pneumonia and severe mitral regurgitation, associated with four vegetations on the atrial surface of the posterior mitral leaflet; in addition, there was rupture and prolapse of its middle scallop. The S. pneumoniae bacterium was isolated from cerebrospinal fluid and blood cultures. In consequence, the patient was given broad-spectrum antibiotic therapy and had an early valve replacement performed, obtaining a good clinical outcome. The key prognostic factor of the Austrian syndrome is determined by the damage of cardiac valves, particularly in patients with a compromised aortic valve; hence, it is necessary to identify the degree of valve injury and define surgical and antibiotic treatment on a timely fashion. However, in subacute, less frequent clinical cases where the mitral valve is the main valve compromised, usually a directed antibiotic therapy associated with advanced support measures are sufficient to control this infection.
authors.affiliation: Oficina de Epidemiologia Hospitalaria, Corporación Comfenalco Valle-Universidad Libre, Cali, Colombia.
authors.forename: Daniel
authors.initials: D
authors.lastname: Echeverri
authors.affiliation: Departamento de Medicina Interna, Universidad CES, Medellín, Colombia.
authors.forename: María de los Ángeles
authors.initials: Mde L
authors.lastname: Vargas
authors.affiliation: Oficina de Epidemiologia Hospitalaria, Corporación Comfenalco Valle-Universidad Libre, Cali, Colombia.
authors.forename: Lorena
authors.initials: L
authors.lastname: Matta
authors.affiliation: Departamento de Infectología Clínica, Fundación Valle del Lili, Cali, Colombia.
authors.forename: Fernando
authors.initials: F
authors.lastname: Rosso
authors.affiliation: Oficina de Epidemiologia Hospitalaria, Corporación Comfenalco Valle-Universidad Libre, Cali, Colombia.
authors.forename: Janier Daniel
authors.initials: JD
authors.lastname: Segura
mesh_terms: D004697:Endocarditis, Bacterial / Q000382:microbiology*; D006801:Humans; D008297:Male; D008586:Meningitis, Pneumococcal / Q000382:microbiology*; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000382:microbiology*; D011018:Pneumonia, Pneumococcal / Q000382:microbiology*; D013577:Syndrome