title: Current Developments and Future Prospects for Plant-Made Biopharmaceuticals Against Rabies.
abstract: Rabies is a prevalent health problem in developing countries. Although vaccines and immunoglobulin treatments are available, their cost and multiple-dose treatments restrict availability. During the last two decades, plants have served as a low-cost platform for biopharmaceuticals production and have been applied to fight against rabies during the last two decades. Herein, I provide a description of the state of the art in the development of plant-made pharmaceuticals against rabies and identify key prospects for the field in terms of novel strategies, immunogen design, and therapeutic antibodies production.
authors.affiliation: Laboratorio de Biofarmacéuticos Recombinantes, Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Av. Dr. Manuel Nava 6, 78210, San Luis Potosí, SLP, México, rosales.s@fcq.uaslp.mx.
authors.forename: Sergio
authors.initials: S
authors.lastname: Rosales-Mendoza
mesh_terms: D000998:Antiviral Agents / Q000191:economics* / Q000627:therapeutic use; D006801:Humans; D030821:Plants, Genetically Modified / Q000378:metabolism; D011818:Rabies / Q000188:drug therapy* / Q000276:immunology / Q000517:prevention & control*; D011819:Rabies Vaccines / Q000191:economics; D011994:Recombinant Proteins / Q000235:genetics / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D011819:Rabies Vaccines; D011994:Recombinant Proteins