title: Targeting female hormone receptors as cervical cancer therapy.
abstract: While preventive methods for cervical cancer are effective, available therapies for advanced cervical cancers are ineffective. New experimental evidence points to weaknesses of prior studies and provides fresh molecular insights on the opposing roles of estrogen receptor alpha (ERα) and the progesterone receptor (PR) that may be translated into valuable treatments for a subset of cervical cancers.
authors.affiliation: Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA. Electronic address: schung@uh.edu.
authors.forename: Sang-Hyuk
authors.initials: SH
authors.lastname: Chung
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D047628:Estrogen Receptor alpha / Q000502:physiology*; D005260:Female; D006801:Humans; D051379:Mice; D011980:Receptors, Progesterone / Q000502:physiology*; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy*
chemical_list: D047628:Estrogen Receptor alpha; D011980:Receptors, Progesterone
keywords: cervical cancer; estrogen receptor α; hormonal therapy; human papillomavirus; progesterone receptor