title: [Renal transplantation without maintenance immunosuppression. Identical twins and kidney transplantation following a successful bone marrow graft].
abstract: Renal transplantation without maintenance immunosuppression has been sporadically reported in the literature. The cases include non-adherent patients who discontinued their immunosuppressive medications, transplantation between identical twins, kidney transplantation after a successful bone marrow graft from the same donor and simultaneous bone marrow and kidney transplantation for the treatment of multiple myeloma with associated renal failure. There are also ongoing clinical trials designed to induce donor specific transplant tolerance with infusion of hematopoietic cells from the same kidney donor. Here we describe two cases of renal transplantation without immunosuppression as examples of situations described above.
authors.affiliation: Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: Riad Abdel
authors.initials: RA
authors.lastname: Hadi
authors.affiliation: Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: Gustavo Gomes
authors.initials: GG
authors.lastname: Thomé
authors.affiliation: Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: Adriana Reginato
authors.initials: AR
authors.lastname: Ribeiro
authors.affiliation: Hospital de Clínicas de Porto Alegre, Brazil.
authors.forename: Roberto Ceratti
authors.initials: RC
authors.lastname: Manfro
mesh_terms: D000328:Adult; D016026:Bone Marrow Transplantation; D004200:Diseases in Twins / Q000601:surgery*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D051437:Renal Insufficiency / Q000601:surgery*; D016896:Treatment Outcome; D014430:Twins, Monozygotic