title: Twenty-Year History of the Evolution of Stroke Thrombolysis With Intravenous Alteplase to Reduce Long-Term Disability.
authors.affiliation: From the Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria (B.C.V.C., A.M., S.M.D.); Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia (B.C.V.C., A.M., G.A.D.); and Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (A.M.). bruce.campbell@mh.org.au.
authors.forename: Bruce C V
authors.initials: BC
authors.lastname: Campbell
authors.affiliation: From the Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria (B.C.V.C., A.M., S.M.D.); Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia (B.C.V.C., A.M., G.A.D.); and Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (A.M.).
authors.forename: Atte
authors.initials: A
authors.lastname: Meretoja
authors.affiliation: From the Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria (B.C.V.C., A.M., S.M.D.); Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia (B.C.V.C., A.M., G.A.D.); and Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (A.M.).
authors.forename: Geoffrey A
authors.initials: GA
authors.lastname: Donnan
authors.affiliation: From the Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria (B.C.V.C., A.M., S.M.D.); Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia (B.C.V.C., A.M., G.A.D.); and Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland (A.M.).
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Davis
mesh_terms: D061605:Administration, Intravenous; D002543:Cerebral Hemorrhage / Q000139:chemically induced / Q000453:epidemiology; D006233:Persons with Disabilities; D006801:Humans; D016032:Randomized Controlled Trials as Topic / Q000639:trends*; D012307:Risk Factors; D020521:Stroke / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D015912:Thrombolytic Therapy / Q000639:trends*; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D010959:Tissue Plasminogen Activator
keywords: Institute of Neurological Disorders and Stroke; National; cerebral infarction; computerized tomography; numbers need to treat; stroke; tissue-type plasminogen activator