title: Image-Based Assessment of Allergic Inflammation under Conjunctival Provocation.
abstract: Conjunctival redness is an objective allergy symptom which can be analyzed using objective computer imaging methods. To evaluate allergic inflammation of the eyes, a robust and precise image-based method was developed and applied to analyze allergic hyperemia under the conjunctival provocation test (CPT). High-resolution digital photos were taken and analyzed via digital analysis software to obtain and document conjunctival redness. The evaluations made using this newly developed image-based method concurred with the study investigators' assessments: the therapeutic effects of the highest doses were superior to the lowest dose.
authors.affiliation: Institute of Medical Statistics, Informatics and Epidemiology, University Hospital of Cologne, Cologne, Germany.
authors.forename: Anatoli
authors.initials: A
authors.lastname: Astvatsatourov
authors.affiliation: Institute of Medical Statistics, Informatics and Epidemiology, University Hospital of Cologne, Cologne, Germany.
authors.forename: Ralph
authors.initials: R
authors.lastname: Mösges
mesh_terms: D000485:Allergens / Q000009:adverse effects*; D003228:Conjunctiva / Q000000981:diagnostic imaging*; D019937:Diagnostic Techniques and Procedures; D006801:Humans; D006967:Hypersensitivity / Q000503:physiopathology*; D007090:Image Interpretation, Computer-Assisted; D010781:Photography; D012720:Severity of Illness Index
chemical_list: D000485:Allergens