title: Multifocal sclerosing angiomatoid nodular transformation of the spleen: a case report and review of literature.
abstract: Sclerosing angiomatoid nodular transformation (SANT) is a relatively new entity in the spleen, which usually presents in the form of single nodule. Only 5 multifocal SANT cases have been reported in English literature. The present case is the first report of a 38-years-old male patient with SANT in the form of multiple nodules, who has been cured via laparoscope. In comparison to solitary SANT, multifocal SANT occurs more likely in males than females and association with malignant neoplasm has not been described yet. Multifocal SANT as well as solitary SANT show some relationships with IgG4-related sclerosing disease.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, P.R. China; Shandong Provincial Key Laboratory of Otology, NO 4, Duanxing Road (West), HuaiYin District, Jinan, P.R. China.|Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, Shandong Prov, China.
authors.forename: Zhixin
authors.initials: Z
authors.lastname: Cao
authors.affiliation: Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, Shandong Prov, China.
authors.forename: Qiangxiu
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, Shandong Prov, China.
authors.forename: Jiamei
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, Shandong Prov, China.
authors.forename: Jiawen
authors.initials: J
authors.lastname: Xu
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, P.R. China; Shandong Provincial Key Laboratory of Otology, NO 4, Duanxing Road (West), HuaiYin District, Jinan, P.R. China. lijianfeng@hotmail.com.|Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan City, Shandong Prov, China. lijianfeng@hotmail.com.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Li
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D018219:Histiocytoma, Benign Fibrous / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D010535:Laparoscopy; D008297:Male; D013156:Splenectomy / Q000379:methods; D013158:Splenic Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers