title: Hepatitis viruses exploitation of host DNA methyltransferases functions.
abstract: Hepatitis B virus (HBV), hepatitis C virus (HCV) and Delta (HDV) infections are a global health burden. With different routes of infection and biology, HBV, HCV and HDV are capable to induce liver cirrhosis and cancer by impinging on epigenetic mechanisms altering host cell's pathways. In the present manuscript, we reviewed the published studies taking into account the relationship between the hepatitis viruses and the DNA methyltransferases proteins.
authors.affiliation: Gastroenterology Unit, Fondazione "Casa Sollievo della Sofferenza" IRCCS Hospital, San Giovanni Rotondo, FG, Italy. pazienza_valerio@yahoo.it.
authors.forename: Valerio
authors.initials: V
authors.lastname: Pazienza
authors.affiliation: Gastroenterology Unit, Fondazione "Casa Sollievo della Sofferenza" IRCCS Hospital, San Giovanni Rotondo, FG, Italy.
authors.forename: Concetta
authors.initials: C
authors.lastname: Panebianco
authors.affiliation: Gastroenterology Unit, Fondazione "Casa Sollievo della Sofferenza" IRCCS Hospital, San Giovanni Rotondo, FG, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Andriulli
mesh_terms: D019175:DNA Methylation; D044127:Epigenesis, Genetic; D016174:Hepacivirus / Q000472:pathogenicity*; D006515:Hepatitis B virus / Q000472:pathogenicity*; D003698:Hepatitis Delta Virus / Q000472:pathogenicity*; D054884:Host-Pathogen Interactions; D006801:Humans; D008780:Methyltransferases / Q000378:metabolism*
chemical_list: D008780:Methyltransferases
keywords: DNMTs; Epigenetics; Hepatitis viruses; Interferon