title: Combination of retrograde superselective intra-arterial chemotherapy and Seldinger method in locally advanced oral cancer.
abstract: The nonsurgical strategies for locally advanced oral cancer are desirable. Superselective intra-arterial infusion with radiotherapy was utilized for this purpose, and there are two types of superselective intra-arterial infusion methods: The Seldinger method and the retrograde superselective intra-arterial chemotherapy (HFT method). In one case, the HFT method was applied to locally advanced tongue cancer, and the Seldinger method was used for additional administration of cisplatin (CDDP) to compensate for a lack of drug flow in the HFT method. In another case, the HFT method was applied to locally advanced lower gingival cancer. The Seldinger method was applied to metastatic lymph nodes. In both cases, additional administration of CDDP using the Seldinger method resulted in a complete response. The combination of the HFT and Seldinger methods was useful to eradicate locally advanced oral cancer because each method compensated for the defects of the other.
authors.affiliation: Department of Science of Physical Functions, Division of Maxillofacial Surgery, Kyushu Dental University, Kitakyushu, Fukuoka, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Uehara
authors.forename: Ryouichi
authors.initials: R
authors.lastname: Ohya
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kodama
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shiraishi
authors.forename: Izumi
authors.initials: I
authors.lastname: Asahina
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tominaga
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy; D017024:Chemotherapy, Adjuvant / Q000379:methods; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods; D008198:Lymph Nodes / Q000187:drug effects / Q000528:radiation effects; D008207:Lymphatic Metastasis / Q000532:radiotherapy; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin