title: [INDUCTION OF ANESTHESIA ON THE BASIS OF DESFLURANE AND FENTANYL--DANGER IN THE AMBULATORY SURGERY].
abstract: OBJECTIVE
  To study the possibility of desflurane use for induction of anesthesia.
  
  
  METHODS
  We analysed the intra- and immediate postoperative periods in 125 patients. Depending on the intended anesthesia method patients were randomised (the method of the envelopes) and included in one of two study groups: 1--volatile desflurane-based anesthesia (n = 62); 2--volatile sevoflurane-based anesthesia (n = 63).
  
  
  RESULTS
  Desflurane based anesthesia led to apnea until the installation of laryngeal mask in 94.5% of patients (of 54), for whom a completion of inhalation induction was possible, whereas sevoflurane based anesthesia.led to apnea occurred only in one patient (1.6%).
  
  
  CONCLUSIONS
  "Step up" desflurane-based inhalational induction and sevoflurane-based maximum concentration inhalational induction "without primaryfilling of the circuit" showed no significant in time necessary for achieving an anesthetic concentration essential for LMA installation. In both groups it was 3-5 min. desflurane-based volatile induction with addition of fentanyl led to apnea in 97% of patients and associates with a higher risk of bronchospasm.
authors.forename: M R
authors.initials: MR
authors.lastname: Khalimov
authors.forename: A M
authors.initials: AM
authors.lastname: Ovezov
authors.forename: O A
authors.initials: OA
authors.lastname: Grebenchikov
authors.forename: M A
authors.initials: MA
authors.lastname: Shapkin
authors.forename: V V
authors.initials: VV
authors.lastname: Likhvantsev
mesh_terms: D000328:Adult; D000556:Ambulatory Surgical Procedures / Q000379:methods*; D000768:Anesthesia, General / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000009:adverse effects*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000009:adverse effects*; D000077335:Desflurane; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000009:adverse effects*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D007826:Laryngismus / Q000139:chemically induced / Q000453:epidemiology; D008297:Male; D011446:Prospective Studies; D012119:Respiration / Q000187:drug effects; D012121:Respiration, Artificial
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D000077335:Desflurane; D007530:Isoflurane; D005283:Fentanyl