title: Iron(II)-Catalyzed Asymmetric Epoxidation of Trisubstituted α,β-Unsaturated Esters.
abstract: An asymmetric epoxidation of trisubstituted α,β-unsaturated esters is described. The oxidation utilizes a pseudo-C2-symmetric iron(II) catalyst [Fe(L*)2(CH3CN)(OTf)](OTf) and peracetic acid as oxidant, yielding the α,β-epoxyesters in high enantiomeric purity (up to 99% ee).
authors.affiliation: Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637 (United States).
authors.forename: Lan
authors.initials: L
authors.lastname: Luo
authors.affiliation: Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637 (United States), Molecular Catalyst Research Center, Chubu University, 1200 Matsumoto, Kasugai, Aichi 487-8501 (Japan).
authors.forename: Hisashi
authors.initials: H
authors.lastname: Yamamoto
keywords: asymmetric epoxidation; iron; α, β-unsaturated ester