title: [Analysis of antimicrobial resistance results of Vibrio parahaemolyticus isolated from shellfish and its habitat in 2013].
abstract: OBJECTIVE
  To evaluate the antimicrobial resistance of Vibrio parahaemolyticus isolated from shellfish and its habitat in Sichuan, Fujian and Guangxi.
  
  
  METHODS
  The susceptibility of 186 isolates of Vibrio parahaemolyticus to 8 antibiotics were determined by broth microdilution susceptibility test. The antibiotics of ampicillin, cefotaxime, ceftazidime, gentamicin, tetracycline, chloramphenicol, ciprofloxacin and trimethoprim/sulfamethoxazole were used.
  
  
  RESULTS
  The antibiotic resistance rate were 69.35% in which ampicillin resistance was the most prevalent. The geometric mean of ampicillin MIC value of all isolates was greater than the interpretation value of resistance. Among the 186 tested isolates, the multiple antibiotic resistance and/or intermediate resistance was 4. All strains were 100% sensitive to cefotaxime, ceftazidime, chloramphenicol and ciprofloxacin. The ampicillin susceptibility spectrum of aquaculture farm was the highest among the three sectors as 73.68% and Sichuan was the highest among the three provinces as 70.94% although there were no significant differences. There were 44 samples out of which 2 and above strains were isolated, and the susceptibility spectrum polymorphism rate of strains isolated from the same sample was 77.27% (34/44).
  
  
  CONCLUSIONS
  The ampicillin resistance rate is relatively high, and shellfish habitat may be the main source of antimicrobial resistance of Vibrio parahaemolyticus. There is an urgent need to strengthen the surveillance and management of Vibrio parahaemolyticus in the shellfish breeding process.
authors.forename: Haihong
authors.initials: H
authors.lastname: Han
authors.forename: Fengqin
authors.initials: F
authors.lastname: Li
authors.forename: Jin
authors.initials: J
authors.lastname: Xu
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.forename: Dongmin
authors.initials: D
authors.lastname: Yu
authors.forename: Shaofei
authors.initials: S
authors.lastname: Yan
authors.forename: Qing
authors.initials: Q
authors.lastname: Wu
authors.forename: Weiwei
authors.initials: W
authors.lastname: Li
authors.forename: Yunchang
authors.initials: Y
authors.lastname: Guo
authors.forename: Ning
authors.initials: N
authors.lastname: Li
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents; D002681:China; D002701:Chloramphenicol / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D017753:Ecosystem; D005839:Gentamicins; D008826:Microbial Sensitivity Tests; D008974:Mollusca; D012758:Shellfish; D014735:Vibrio Infections / Q000188:drug therapy / Q000382:microbiology; D014736:Vibrio parahaemolyticus / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D005839:Gentamicins; D002939:Ciprofloxacin; D002701:Chloramphenicol