title: Reliability testing of oxaliplatin-associated neurotoxicity questionnaire (OANQ), a pilot study.
abstract: OBJECTIVE
  The purpose of this study was to test the reliability of the Swedish version of the Oxaliplatin-Associated Neurotoxicity Questionnaire (OANQ) administrated throughout a self-reported mobile phone-based system, a pilot study.
  
  
  METHODS
  Twenty-three patients from two university hospitals and two regional hospitals who had been treated with oxaliplatin were included through purposive sampling between autumn 2013 to autumn 2014. A test-retest was performed through a mobile phone-based system, with a recall period of 1 h to determine the reliability of the questionnaire.
  
  
  RESULTS
  Internal consistency was strong for the three domains of the scale (α > 0.840). The statistical analyses for the test-retest indicated that the OANQ was stable. Intraclass correlation (ICC) for symptom items and effect on daily activities items showed an overall excellent reproducibility at 69 and 83 %, respectively. The weighted kappa for symptom items and daily activities items showed an overall almost perfect agreement at 59 and 52 %, respectively. A paired samples t test did not reveal any significant differences between the two measures.
  
  
  CONCLUSIONS
  The OANQ was tested and considered a reliable assessment for capturing the oxaliplatin-induced peripheral neurotoxicity (OIPN) in patients receiving oxaliplatin. However, further reliability testing of the OANQ is needed.
authors.affiliation: Department of Surgery and Department of Medical and Health Sciences, Linköping University, 581 85, Linköping, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Gustafsson
authors.affiliation: Department of Surgery and Department of Medical and Health Sciences, Linköping University, 581 85, Linköping, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Litström
authors.affiliation: Division of Nursing Science, Department of Medical and Health Sciences, Linköping University, 581 85, Linköping, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Berterö
authors.affiliation: Department of Surgery and Department of Medical and Health Sciences, Linköping University, 581 85, Linköping, Sweden. Jenny.Drott@liu.se.|Division of Nursing Science, Department of Medical and Health Sciences, Linköping University, 581 85, Linköping, Sweden. Jenny.Drott@liu.se.
authors.forename: J
authors.initials: J
authors.lastname: Drott
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020258:Neurotoxicity Syndromes / Q000209:etiology*; D009944:Organoplatinum Compounds / Q000008:administration & dosage / Q000009:adverse effects*; D000077150:Oxaliplatin; D010865:Pilot Projects; D015203:Reproducibility of Results; D057566:Self Report; D011795:Surveys and Questionnaires
chemical_list: D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin
keywords: Oxaliplatin; Oxaliplatin-induced peripheral neurotoxicity; Symptom