title: The Prognostic Scale CRASH in the Treatment of Children with Severe Traumatic Brain Injury.
abstract: The aim of the present study was to assess the effectiveness and validity of prognostic scale CRASH which is calculated using on-line resources and which may serve as a decision support for physicians in treating severe traumatic brain injury (TBI) in children. This retrospective study was conducted using clinical and physiological data of 168 hospitalized pediatric patients with severe traumatic brain injury (GCS score less than or equal to 8). CRASH scale was used for calculating the severity of patients' state and for prognosing death outcomes at 14 days and at 6 months using the on-line resource. Our research has shown that the prognostic scale CRASH has an excellent discrimination ability (AUROC=0.816) in each version. The study has also shown that the scale has a satisfactory calibration ability in the option of 14 days with CT (χ2 equal 8.7 and p-value equal to 0.368). Calibration ability for other options was unsatisfactory. Thus, CRASH scale with CT scan has turned to be useful for assessing death outcomes at 14 days in children with severe TBI.
authors.affiliation: Clinical and Research Institute of Urgent Pediatric Surgery and Trauma, Moscow, Russia.
authors.forename: Irina Vitalevna
authors.initials: IV
authors.lastname: Vasilyeva
authors.affiliation: Clinical and Research Institute of Urgent Pediatric Surgery and Trauma, Moscow, Russia.
authors.forename: Semen Vladimirivich
authors.initials: SV
authors.lastname: Mesherakov
authors.affiliation: Clinical and Research Institute of Urgent Pediatric Surgery and Trauma, Moscow, Russia.
authors.forename: Sergey Borosovich
authors.initials: SB
authors.lastname: Arseniev
authors.affiliation: Clinical and Research Institute of Urgent Pediatric Surgery and Trauma, Moscow, Russia.
authors.forename: Zanna Borisovna
authors.initials: ZB
authors.lastname: Semenova
mesh_terms: D000367:Age Factors; D000070642:Brain Injuries, Traumatic / Q000401:mortality*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D015599:Trauma Severity Indices