title: Pd/C-catalyzed, copper-free Sonogashira coupling: one-pot synthesis of 1-aryl-4-(2-phenylethynyl)[1,2,4]triazolo[4,3-a]quinoxalines in water.
abstract: Copper-free, Pd/C-catalyzed, one-pot reaction of 2,3-dichloroquinoxaline with hydrazine hydrate, bromine, phenylacetylene, and a variety of aldehydes provides an efficient and direct method for the preparation of 1-aryl-4-(2-phenylethynyl)[1,2,4]triazolo[4,3-a]quinoxalines in water at 70 °C. This methodology involves the use of inexpensive reagents or catalysts, and thus permits a new and practical access to triazolo[4,3-a]quinoxalines.
authors.affiliation: School of Chemistry, Shahrood University of Technology, Shahrood, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Bakherad
authors.affiliation: School of Chemistry, Shahrood University of Technology, Shahrood, Iran.
authors.forename: Saeideh
authors.initials: S
authors.lastname: Jajarmi
keywords: Palladium catalyst; Phenylacetylene; Sonogashira reaction; Triazoloquinoxaline