title: Relationship between optimism and quality of life in patients with two chronic rheumatic diseases: axial spondyloarthritis and chronic low back pain: a cross sectional study of 288 patients.
abstract: BACKGROUND
  Axial Spondyloarthritis (AxSpA) and chronic low back pain are rheumatic diseases that impact patients' health-related quality of life (HRQoL). In other chronic conditions, HRQoL was positively associated with dispositional optimism, a personality trait. The objective was to explore the relationship between optimism and HRQoL in these two diseases.
  
  
  METHODS
  A cross-sectional study was performed in 2 tertiary care hospitals and 2 private practices in France. Patients had definite AxSpA or chronic low back pain according to the rheumatologist. A generic HRQoL questionnaire (Short Form, SF-12) with physical and mental composite scores (PCS and MCS respectively) and an optimism questionnaire (the Life Orientation Test-revised, LOT-R) were collected. Analyses included non-parametric correlations and multiple regression analyses to study the effect of optimism on PCS and MCS.
  
  
  RESULTS
  In all, 288 (199 AxSpA and 89 low back pain) patients were included: mean age, 47.3 ± 11.9 years, 48.6 % were males. Pain levels (0-10) were 4.5 ± 2.4 and 4.3 ± 2.4 in AxSpA and LOW BACK PAIN patients, respectively. HRQoL was similarly altered in both diseases, for both physical and mental composite scores (mean PCS: 43.7 ± 8.2 vs. 41.9 ± 7.1; mean
  45.9 ± 7.8 vs. 46.7 ± 8.1 for AxSpA and low back pain respectively). Optimism was moderate and similar in both populations. Optimism was positively correlated to MCS in both diseases (rho = 0.54 and 0.58, respectively, both p <0.01) and these relations persisted in multivariate analyses (beta = 1.03 and 1.40, both p <0.0001).
  
  
  CONCLUSIONS
  Optimism was similar in these 2 chronic diseases and was an explanatory factor of the mental component of HRQoL, but not physical HRQoL. Physical HRQoL may reflect more the disease process than character traits.
authors.affiliation: Institute of Psychology, Laboratoire Adaptations Travail - Individu, University Paris Descartes, Sorbonne-Paris cité, Paris, France. kreis.sarah@gmail.com.|Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. kreis.sarah@gmail.com.|Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. kreis.sarah@gmail.com.
authors.forename: Sarah
authors.initials: S
authors.lastname: Kreis
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. anna.molto@cch.aphp.fr.|Rheumatology Department, Cochin Hospital, AP-HP. INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris Descartes University, Paris, France. anna.molto@cch.aphp.fr.
authors.forename: Anna
authors.initials: A
authors.lastname: Molto
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. baillyflorian@yahoo.fr.|Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. baillyflorian@yahoo.fr.
authors.forename: Florian
authors.initials: F
authors.lastname: Bailly
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. sabrinadadoun@gmail.com.|Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. sabrinadadoun@gmail.com.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Dadoun
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. stephaniefabre.p@gmail.com.
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Fabre
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. rein.christo@gmail.com.|Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. rein.christo@gmail.com.
authors.forename: Christopher
authors.initials: C
authors.lastname: Rein
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. dr.hudry@orange.fr.
authors.forename: Christophe
authors.initials: C
authors.lastname: Hudry
authors.affiliation: Institute of Psychology, Laboratoire Adaptations Travail - Individu, University Paris Descartes, Sorbonne-Paris cité, Paris, France. franck.zenasni@gmail.com.
authors.forename: Franck
authors.initials: F
authors.lastname: Zenasni
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. sylvie.rozenberg@psl.aphp.fr.|Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. sylvie.rozenberg@psl.aphp.fr.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Rozenberg
authors.affiliation: Pontoise University Hospital, Pontoise, France. edouard.pertuiset@ch-pontoise.fr.
authors.forename: Edouard
authors.initials: E
authors.lastname: Pertuiset
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. bruno.fautrel@psl.aphp.fr.|Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. bruno.fautrel@psl.aphp.fr.
authors.forename: Bruno
authors.initials: B
authors.lastname: Fautrel
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France. laure.gossec@psl.aphp.fr.|Rheumatology Department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France. laure.gossec@psl.aphp.fr.|CHU Pitié Salpêtrière, Service de Rhumatologie, Pavillon Delessert, 47-83 bd de l'hôpital, 75013, Paris, France. laure.gossec@psl.aphp.fr.
authors.forename: Laure
authors.initials: L
authors.lastname: Gossec
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D002908:Chronic Disease / Q000523:psychology; D003430:Cross-Sectional Studies; D005260:Female; D005602:France; D006305:Health Status Indicators; D006801:Humans; D017116:Low Back Pain / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D000067656:Optimism; D010551:Personality; D011788:Quality of Life / Q000523:psychology*; D012044:Regression Analysis; D025241:Spondylarthritis / Q000523:psychology*