title: [Studies on chemical constituents of Zhuang medicine Excoecaria venenata and their cytotoxic activity].
abstract: Fourteen compounds were isolated from 95% ethanol extract by silica gel, MCI, and ODS column chromatography. These compounds were respectively identified as quercetin (1), kaempferol (2), (+)-catechin (3), fraxin (4), protocatechuic acid (5), gallic acid (6), methyl gallate (7), ethyl gallate (8), apocynol A (9), baccatin (10), cerevisterol (11), ellagic acid (12), 3, 3',4'-tri-0-methylellagic acid(13) and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate(14) by analyzing their spectral data and comparing with the previously reported literatures. Except for gallic acid (6), all other compounds were isolated from this plant for the first time. Compounds 1, 2 and 6 showed moderate anti-proliferation activities on tumor cells.
authors.forename: De-sheng
authors.initials: DS
authors.lastname: Ning
authors.forename: Xiao-xu
authors.initials: XX
authors.lastname: Yan
authors.forename: Si-si
authors.initials: SS
authors.lastname: Huang
authors.forename: Ling
authors.initials: L
authors.lastname: Cheng
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Zheng-hong
authors.initials: ZH
authors.lastname: Pan
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000633:toxicity*; D019665:Euphorbiaceae / Q000737:chemistry*; D006801:Humans; D010946:Plants, Medicinal / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D004365:Drugs, Chinese Herbal