title: Safety and Efficacy of One-stage Spinal Osteotomy for Severe and Rigid Congenital Scoliosis Associated with Split Spinal Cord Malformation.
abstract: METHODS
  Retrospective clinical study.
  
  
  OBJECTIVE
  To retrospectively evaluate the safety and efficacy of one-stage spinal osteotomy in the treatment of severe and progressive congenital scoliosis (CS) associated with split spinal cord malformation (SSCM).
  
  
  BACKGROUND
  For severe and rigid spinal deformity, spinal osteotomies are often advocated for correcting the deformity. However, the safety and efficacy of one-stage spinal osteotomy in the treatment of severe and rigid CS with SSCM have been unclear thus far.
  
  
  METHODS
  Patients were treated by one-stage spinal osteotomy between September 2007 and June 2011 in our hospital. The clinical records were reviewed for demographic and radiographical data, operative time, intraoperative blood loss, blood transfusion, perioperative complications, and functional outcomes.
  
  
  RESULTS
  There were 18 females and 11 males with an average age of 15.5 ± 3.6 years (range, 12-28 yr). Spinal cord was longitudinally split by a bony spur in 11 patients (type I SSCM) and by a fibrous band in 18 patients (type II SSCM). Patients were observed for a minimum of 24 months after initial surgical treatment with an average follow-up of 43.0 ± 17.1 months (range 24-68 mo) from September 2007 to June 2013. The mean operative time and average blood loss of type ISSCM was significantly greater than those of type II SSCM (P < 0.05). The major curve was corrected from an average of 97.2°± 17.8° to 35.7°± 15.9°, a mean correction rate of 64.3% ± 11.0%. The average loss of correction at final follow-up was 2.9% for major curves. The overall complication rate was 24.1%, including transient neurological deterioration in 3 patients, cerebrospinal fluid leakage in 2 patients, urinary tract infection in 1 patient and pleural rupture in 1 patient.
  
  
  CONCLUSIONS
  Relative to multistage corrective surgery, one-stage spinal osteotomy is effective for the correction of severe CS and SSCM without increasing the rate of surgical complications. However, surgical treatment of type I SSCM does require more operating time and blood loss.
  
  
  METHODS
  4.
authors.affiliation: *Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, China †Sonoran Spine Center, Mesa, AZ; and ‡Department of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.forename: Zhi
authors.initials: Z
authors.lastname: Yuan
authors.forename: Michael S
authors.initials: MS
authors.lastname: Chang
authors.forename: Jing-Hui
authors.initials: JH
authors.lastname: Huang
authors.forename: Huan
authors.initials: H
authors.lastname: Li
authors.forename: Wei-Zhou
authors.initials: WZ
authors.lastname: Yang
authors.forename: Zhuo-Jing
authors.initials: ZJ
authors.lastname: Luo
authors.forename: Hui-Ren
authors.initials: HR
authors.lastname: Tao
mesh_terms: D000015:Abnormalities, Multiple; D000293:Adolescent; D000328:Adult; D016063:Blood Loss, Surgical; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009436:Neural Tube Defects / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D061646:Operative Time; D010027:Osteotomy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D011183:Postoperative Complications / Q000209:etiology; D011859:Radiography; D020127:Recovery of Function; D012189:Retrospective Studies; D012307:Risk Factors; D012600:Scoliosis / Q000151:congenital / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D012720:Severity of Illness Index; D013116:Spinal Cord / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D013131:Spine / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult