title: Synthesis of unsymmetrical alkyl acetals via addition of primary alcohols to allyl ethers mediated by ruthenium complexes.
abstract: Ru-catalyzed synthesis of mixed alkyl-alkyl acetals via addition of primary alcohols to allyl ethers has been extended to include long-chain and/or functionalized substrates. The catalytic systems for these reactions were generated from RuCl2(PPh3)3and [RuCl2(1,5-COD)]xand phosphines [PPh3or P(p-chlorophenyl)3] or SbPh3. Of particular importance is the almost quantitative elimination of transacetalization. The addition proceeds through allyl complexes, not via isomerization of allyl ethers--subsequent addition of ROH to vinyl ethers.
authors.affiliation: Institute of Chemistry, University of Silesia, Katowice, Poland.
authors.forename: Stanisław
authors.initials: S
authors.lastname: Krompiec
authors.affiliation: Institute of Chemistry, University of Silesia, Katowice, Poland.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Penkala
authors.affiliation: Institute of Chemistry, University of Silesia, Katowice, Poland.
authors.forename: Ewelina
authors.initials: E
authors.lastname: Kowalska
authors.affiliation: Institute of Chemistry, University of Silesia, Katowice, Poland.
authors.forename: Robert
authors.initials: R
authors.lastname: Penczek
authors.affiliation: Institute of Chemistry, University of Silesia, Katowice, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Bujak
authors.affiliation: Institute of Organic Chemistry, Polish Academy of Science, Warsaw, Poland.
authors.forename: Witold
authors.initials: W
authors.lastname: Danikiewicz
authors.affiliation: Institute of Organic Chemistry, Polish Academy of Science, Warsaw, Poland.
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Spólnik
authors.affiliation: Institute of Chemistry, University of Silesia, Katowice, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Kita
authors.affiliation: Institute of Chemistry, University of Silesia, Katowice, Poland.
authors.forename: Iwona
authors.initials: I
authors.lastname: Grudzka
keywords: Chemoselectivity; Homogeneus catalysis; Metal complexes; Mixed acetals