title: Metabolic Syndrome in Polish Ischemic Stroke Patients.
abstract: BACKGROUND
  Metabolic syndrome (MetS) predisposes individuals to cardiovascular disease or stroke development. We aimed at evaluating the prevalence of MetS in a population of acute ischemic stroke (IS) patients from central Poland and at estimating the relationship between MetS and stroke risk.
  
  
  METHODS
  We analyzed 672 IS patients who were consecutively admitted to stroke units. The control group was composed of 612 patients with other neurologic disorders. MetS was diagnosed if 3 of 5 factors were present (obesity, increased blood pressure, increased triglycerides, low high-density lipoprotein [HDL] cholesterol, and fasting hyperglycemia) according to the Unified Criteria for Clinical Diagnosis of the Metabolic Syndrome (2009).
  
  
  RESULTS
  MetS was diagnosed in 61.2% of stroke patients versus 18.1% of the control group (P < .001). Multiple logistic regression showed that MetS was 1.8 times more common in women than in men (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.4-2.5). The adjusted OR (95% CI) associated with MetS was 2.44 (1.48-3.64; P < .001) for IS. Hypertension and hypertriglyceridemia were the most frequent disturbances of IS patients (87.2% and 68.2%, respectively). The analysis of the interaction between MetS and its components showed significant associations with hypertension (OR, 2.15; 95% CI, .98-4.24; P < .01), high triglyceride levels (OR, 4.35; 95% CI, 2.87-9.43; P < .0001), and low HDL cholesterol levels (OR, 5.12; 95% CI, 3.15-8.20; P < .001).
  
  
  CONCLUSIONS
  Over 60% of Polish IS patients have MetS. The prevalence of MetS was significantly higher in women than in men. Thus, MetS may be a risk factor for IS.
authors.affiliation: Department of Neurology and Stroke Unit, Specialist Hospital in Końskie, Końskie, Poland. Electronic address: wbrola@wp.pl.
authors.forename: Waldemar
authors.initials: W
authors.lastname: Brola
authors.affiliation: Department of Neurology and Stroke Unit, Holy Spirit Specialist Hospital in Sandomierz, Sandomierz, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Sobolewski
authors.affiliation: Department of Neurology and Stroke Unit, Specialist Hospital in Końskie, Końskie, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Fudala
authors.affiliation: Department of Neurology and Stroke Unit, Specialist Hospital in Końskie, Końskie, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Goral
authors.affiliation: Department of Neurology and Stroke Unit, Specialist Hospital in Końskie, Końskie, Poland.
authors.forename: Marta
authors.initials: M
authors.lastname: Kasprzyk
authors.affiliation: Department of Neurology and Stroke Unit, Holy Spirit Specialist Hospital in Sandomierz, Sandomierz, Poland.
authors.forename: Wiktor
authors.initials: W
authors.lastname: Szczuchniak
authors.affiliation: Department of Internal Disease, Specialist Hospital in Końskie, Końskie, Poland.
authors.forename: Renata
authors.initials: R
authors.lastname: Pejas-Dulewicz
authors.affiliation: Paediatric Department, Specialist Hospital in Końskie, Końskie, Poland; The Faculty of Health Science, Institute of Nursing and Obstetrics, Jan Kochanowski University, Kielce, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Przybylski
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D015992:Body Mass Index; D002545:Brain Ischemia / Q000150:complications*; D008076:Cholesterol, HDL; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008659:Metabolic Diseases / Q000453:epidemiology* / Q000209:etiology*; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D020521:Stroke / Q000150:complications / Q000453:epidemiology / Q000209:etiology; D014280:Triglycerides
chemical_list: D008076:Cholesterol, HDL; D014280:Triglycerides
keywords: Metabolic syndrome; Poland; ischemic stroke; prevalence