title: [Development of a questionnaire to identify patients' preference for a conventional or a direct oral anticoagulant].
abstract: BACKGROUND
  Oral anticoagulant therapy is currently performed using vitamin K-dependent (VKA) or novel, non-vitamin-K-dependent (NOAC) anticoagulants. Patients can thus be involved into the decision process which type of anticoagulants to use. Preference of patients for a specific type of anticoagulants is included in several international guidelines for prophylaxis of embolic events in patients with atrial fibrillation.
  
  
  METHODS
  Description of the development of a short questionnaire to identify this preference in patients treated with VKA.
  
  
  RESULTS
  Using the questionnaires Freiburger personality inventory (FPI-R), health survey SF-12, State-Trait Anxiety Inventory (STAI) and a self-developed questionnaire on anticoagulant therapy, multiple regression analysis identified 7 items for the willingness of patients to change anticoagulation from VKA to NOAC with a probability of about 90%.
  
  
  CONCLUSIONS
  Further investigations have to be performed to identify the preference of patients for anticoagulation with VKA using this short questionnaire.
authors.forename: Shabnam
authors.initials: S
authors.lastname: Zolfaghari
authors.forename: Job
authors.initials: J
authors.lastname: Harenberg
authors.forename: Martin
authors.initials: M
authors.lastname: Wehling
authors.forename: Lutz
authors.initials: L
authors.lastname: Frölich
authors.forename: Christel
authors.initials: C
authors.lastname: Weiss
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage*; D002605:Character; D057915:Drug Substitution / Q000523:psychology; D015507:Drugs, Investigational / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous / Q000523:psychology; D008297:Male; D057240:Patient Preference / Q000523:psychology*; D010555:Personality Inventory / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000188:drug therapy / Q000209:etiology / Q000523:psychology; D011594:Psychometrics / Q000706:statistics & numerical data; D015203:Reproducibility of Results; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013923:Thromboembolism / Q000188:drug therapy* / Q000209:etiology / Q000523:psychology; D014812:Vitamin K / Q000037:antagonists & inhibitors*
chemical_list: D000925:Anticoagulants; D015507:Drugs, Investigational; D014812:Vitamin K