title: Use of dexmedetomidine as an adjunct in the treatment of paradoxical hypertension after surgical repair of coarctation of the aorta in infants.
abstract: Severe persistent hypertension is seen infrequently in newborns and infants, but we came across two infants who developed severe paradoxical hypertension after successful coarctation repair. Treatment of systemic hypertension following repair of coarctation of the aorta is always challenging particularly in infants. Dexmedetomidine was used successfully as an adjunct to the established anti-hypertensive drugs in the immediate postoperative period in our cases to treat postoperative paradoxical hypertension.
authors.affiliation: Department of Intensive Care for CTVS, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Manoj K
authors.initials: MK
authors.lastname: Sahu
authors.forename: Vinod Kumar
authors.initials: VK
authors.lastname: Manikala
authors.forename: Sarvesh Pal
authors.initials: SP
authors.lastname: Singh
authors.forename: A K
authors.initials: AK
authors.lastname: Bisoi
authors.forename: Ujjwal Kumar
authors.initials: UK
authors.lastname: Chowdhury
mesh_terms: D058647:Adrenergic alpha-2 Receptor Agonists / Q000627:therapeutic use; D001017:Aortic Coarctation / Q000150:complications / Q000601:surgery*; D020927:Dexmedetomidine / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D007223:Infant; D008297:Male; D011183:Postoperative Complications / Q000188:drug therapy*
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D020927:Dexmedetomidine