title: Complete Recovery With the Chain of Survival After a Prolonged (120 Minutes) Out-of-Hospital Cardiac Arrest Due to Brugada Syndrome: A Case Report.
abstract: Out-of-hospital cardiac arrest (OHCA) is a crucial public health problem. To improve outcomes of patients after cardiac arrest, the American Heart Association promotes the concept of the chain of survival.We report a case of a 19-year-old man with no markedly past medical history who suffered from OHCA, and he was resuscitated with cardiopulmonary resuscitation, without interruption, during the rescue process for 120 minutes until return of spontaneous circulation (ROSC). Electrocardiogram on admission showed right bundle branch block and ST segment elevation in leads V1-V2, and the patient's uncle had experienced the same event and had received implantable cardioverter defibrillator (ICD) treatment. Therefore, the patient was diagnosed with Brugada syndrome. Postcardiac arrest care was performed after ROSC, including mild therapeutic hypothermia, hemodynamic monitoring and management, and ICD implantation, and then the patient completely recovered without any noticeable neurological or intellectual deficits in the follow-up examinations.Our case demonstrates that even after an OHCA with prolonged time (120 minutes) until ROSC, survival with a favorable neurological outcome is possible, provided implementation of an extremely effective rescue chain.
authors.affiliation: From the Department of Emergency Medicine (FH, PX, JZ, JW); Department of Cardiology (Z-HW), Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
authors.forename: Fei
authors.initials: F
authors.lastname: He
authors.forename: Peng
authors.initials: P
authors.lastname: Xu
authors.forename: Zhong-Hai
authors.initials: ZH
authors.lastname: Wei
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
mesh_terms: D053840:Brugada Syndrome / Q000150:complications* / Q000628:therapy*; D016887:Cardiopulmonary Resuscitation / Q000379:methods; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D006439:Hemodynamics; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods; D008297:Male; D058687:Out-of-Hospital Cardiac Arrest / Q000209:etiology* / Q000628:therapy; D055815:Young Adult