title: Hydration Status Is Associated with Aortic Stiffness, but Not with Peripheral Arterial Stiffness, in Chronically Hemodialysed Patients.
abstract: Background. Adequate fluid management could be essential to minimize high arterial stiffness observed in chronically hemodialyzed patients (CHP). Aim. To determine the association between body fluid status and central and peripheral arterial stiffness levels. Methods. Arterial stiffness was assessed in 65 CHP by measuring the pulse wave velocity (PWV) in a central arterial pathway (carotid-femoral) and in a peripheral pathway (carotid-brachial). A blood pressure-independent regional arterial stiffness index was calculated using PWV. Volume status was assessed by whole-body multiple-frequency bioimpedance. Patients were first observed as an entire group and then divided into three different fluid status-related groups: normal, overhydration, and dehydration groups. Results. Only carotid-femoral stiffness was positively associated (P < 0.05) with the hydration status evaluated through extracellular/intracellular fluid, extracellular/Total Body Fluid, and absolute and relative overhydration. Conclusion. Volume status and overload are associated with central, but not peripheral, arterial stiffness levels with independence of the blood pressure level, in CHP.
authors.affiliation: Physiology Department, School of Medicine, CUiiDARTE, Republic University, 11800 Montevideo, Uruguay.
authors.forename: Daniel
authors.initials: D
authors.lastname: Bia
authors.affiliation: National Council of Technical and Scientific Research (CONICET), C1033AAJ Buenos Aires, Argentina ; Technological National University, C1179AAQ Buenos Aires, Argentina.
authors.forename: Cintia
authors.initials: C
authors.lastname: Galli
authors.affiliation: Fresenius FME Burzaco, B1852FZD Buenos Aires, Argentina.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Valtuille
authors.affiliation: Physiology Department, School of Medicine, CUiiDARTE, Republic University, 11800 Montevideo, Uruguay.
authors.forename: Yanina
authors.initials: Y
authors.lastname: Zócalo
authors.affiliation: Favaloro University, Solis, C1093AAS Buenos Aires, Argentina.
authors.forename: Sandra A
authors.initials: SA
authors.lastname: Wray
authors.affiliation: Technological National University, C1179AAQ Buenos Aires, Argentina ; Favaloro University, Solis, C1093AAS Buenos Aires, Argentina.
authors.forename: Ricardo L
authors.initials: RL
authors.lastname: Armentano
authors.affiliation: National Council of Technical and Scientific Research (CONICET), C1033AAJ Buenos Aires, Argentina ; Technological National University, C1179AAQ Buenos Aires, Argentina ; Favaloro University, Solis, C1093AAS Buenos Aires, Argentina.
authors.forename: Edmundo I
authors.initials: EI
authors.lastname: Cabrera Fischer