title: CGMD: An integrated database of cancer genes and markers.
abstract: Integrating cancer genes and markers with experimental evidence might provide valuable information for the further investigation of crosstalk between tumor genes and markers in cancer biology. To achieve this objective, we developed a database known as the Cancer Gene Marker Database (CGMD), which integrates data on tumor genes and markers based on experimental evidence. The major goal of CGMD is to provide the following: 1) current systematic treatment approaches and recent advances in different cancer treatments; 2) the aggregation of different genes and markers by their molecular characteristics and pathway associations; and 3) free access to the data compiled by CGMD at http://cgmd.in/. The database consists of 309 genes and 206 markers, as well as a list of 40 different human cancers, with detailed descriptions of all characterized markers. CGMD provides complete cancer annotations and molecular descriptions of cancer genes and markers such as CpG islands, promoters, exons, PDB structures, active sites and domains.
authors.affiliation: Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati-517502, Andhra Pradesh, India.
authors.forename: Jangampalli Adi
authors.initials: JA
authors.lastname: Pradeepkiran
authors.affiliation: 1] Department of Biotechnology, Vikrama Simhapuri University, Nellore-524 003, Andhra Pradesh, India [2] CIMAR/CIIMAR, Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Rua dos Bragas, 177, 4050-123 Porto, Portugal.
authors.forename: Sri Bhashyam
authors.initials: SB
authors.lastname: Sainath
authors.affiliation: Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati-517502, Andhra Pradesh, India.
authors.forename: Konidala Kramthi
authors.initials: KK
authors.lastname: Kumar
authors.affiliation: Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati-517502, Andhra Pradesh, India.
authors.forename: Lokanada
authors.initials: L
authors.lastname: Balasubramanyam
authors.affiliation: Department of Biotechnology, Vikrama Simhapuri University, Nellore-524 003, Andhra Pradesh, India.
authors.forename: Kodali Vidya
authors.initials: KV
authors.lastname: Prabhakar
authors.affiliation: Division of Animal Biotechnology, Department of Zoology, Sri Venkateswara University, Tirupati-517502, Andhra Pradesh, India.
authors.forename: Matcha
authors.initials: M
authors.lastname: Bhaskar
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D018899:CpG Islands; D030541:Databases, Genetic; D005091:Exons; D052138:Genes, Neoplasm; D006801:Humans; D020407:Internet; D009369:Neoplasms / Q000235:genetics* / Q000473:pathology; D011401:Promoter Regions, Genetic; D014584:User-Computer Interface
chemical_list: D014408:Biomarkers, Tumor