title: Primary Therapy of Patients with Early Breast Cancer: Evidence, Controversies, Consensus: Opinions of German Specialists to the 14th St. Gallen International Breast Cancer Conference 2015 (Vienna 2015).
abstract: For the first time, this year's St. Gallen International Consensus Conference on the treatment of patients with primary breast cancer, which takes place every two years, was held not in St. Gallen (Switzerland) but - for logistical reasons - in Vienna (Austria) under its usual name. The 2015 St. Gallen International Consensus Conference was the 14th of its kind. As the international panel of the St. Gallen conference consists of experts from different countries, the consensus mirrors an international cross-section of opinions. From a German perspective, it was considered useful to translate the results of the votes of the St. Gallen conference into practical suggestions, particularly in light of the recently updated treatment guideline of the Gynecologic Oncology Group (AGO-Mamma 2015) in Germany. A German group consisting of 14 breast cancer experts, three of whom are members of the international St. Gallen panel, has therefore provided comments on the results of this year's votes at the 2015 St. Gallen Consensus Conference and their impact on clinical care in Germany. The 14th St. Gallen conference once again focused on surgery of the breast and the axilla, radio-oncologic and systemic treatment options for primary breast cancer depending on tumor biology, and the clinical use of multigene assays. The conference also considered targeted therapies for older and for younger patients, including the diagnosis/treatment of breast cancer during and after pregnancy and the preservation of fertility.
authors.affiliation: Klinik für Gynäkologie und Geburtshilfe, interdisziplinäres Brustzentrum, HELIOS Klinikum Berlin Buch, Berlin.
authors.forename: M
authors.initials: M
authors.lastname: Untch
authors.affiliation: Brustzentrum, Frauenklinik der Universität München (LMU), Munich.
authors.forename: N
authors.initials: N
authors.lastname: Harbeck
authors.affiliation: Universitätsfrauenklinik Ulm, Brustzentrum, Ulm.
authors.forename: J
authors.initials: J
authors.lastname: Huober
authors.affiliation: German Breast Group, Neu-Isenburg; Universitäts-Klinikum Frankfurt; Senologische Onkologie, Düsseldorf.
authors.forename: G
authors.initials: G
authors.lastname: von Minckwitz
authors.affiliation: Universitätsfrauenklinik Rostock, Rostock.
authors.forename: B
authors.initials: B
authors.lastname: Gerber
authors.affiliation: Institut für Pathologie, Medizinische Hochschule Hannover, Hanover.
authors.forename: H-H
authors.initials: HH
authors.lastname: Kreipe
authors.affiliation: Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Schleswig-Holstein, Campus Lübeck.
authors.forename: C
authors.initials: C
authors.lastname: Liedtke
authors.affiliation: Gemeinschaftspraxis für interdisziplinäre Onkologie und Hämatologie, Freiburg.
authors.forename: N
authors.initials: N
authors.lastname: Marschner
authors.affiliation: Klinik für Gynäkologie und Geburtshilfe, Klinikum Frankfurt-Höchst, Frankfurt/Main.
authors.forename: V
authors.initials: V
authors.lastname: Möbus
authors.affiliation: Klinik und Poliklinik für Strahlentherapie und Radioonkologie, LMU München, Munich.
authors.forename: H
authors.initials: H
authors.lastname: Scheithauer
authors.affiliation: Nationales Centrum für Tumorerkrankungen (NCT) und Universitätsfrauenklinik Heidelberg, Heidelberg.
authors.forename: A
authors.initials: A
authors.lastname: Schneeweiss
authors.affiliation: Universitätsklinik und Poliklinik für Gynäkologie, Halle (Saale).
authors.forename: C
authors.initials: C
authors.lastname: Thomssen
authors.affiliation: Klinik für Gynäkologie und Geburtshilfe, Sana-Klinikum Offenbach, Offenbach.
authors.forename: C
authors.initials: C
authors.lastname: Jackisch
authors.affiliation: Frauenklinik des Universitätsklinikums Erlangen (Direktor), Comprehensive Cancer Center Erlangen, Erlangen.
authors.forename: M W
authors.initials: MW
authors.lastname: Beckmann
authors.affiliation: Klinik für Gynäkologie und Brustzentrum, Charité Berlin.
authors.forename: J-U
authors.initials: JU
authors.lastname: Blohmer
authors.affiliation: Universitätsfrauenklinik Magdeburg, Magdeburg.
authors.forename: S-D
authors.initials: SD
authors.lastname: Costa
authors.affiliation: Gemeinschaftspraxis Onkologie, Ravensburg, Ravensburg.
authors.forename: T
authors.initials: T
authors.lastname: Decker
authors.affiliation: Gemeinschaftspraxis Gynäkologie und Geburtshilfe, Mannheim.
authors.forename: I
authors.initials: I
authors.lastname: Diel
authors.affiliation: Frauenklinik des Universitätsklinikums Erlangen, Comprehensive Cancer Center Erlangen-Nürnberg, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen.
authors.forename: P A
authors.initials: PA
authors.lastname: Fasching
authors.affiliation: Universitätsfrauenklinik Düsseldorf, Düsseldorf.
authors.forename: T
authors.initials: T
authors.lastname: Fehm
authors.affiliation: Universitätsfrauenklinik Ulm, Ulm.
authors.forename: W
authors.initials: W
authors.lastname: Janni
authors.affiliation: Gynäkologisch-onkologische Praxis, Hannover, Hanover.
authors.forename: H-J
authors.initials: HJ
authors.lastname: Lück
authors.affiliation: Klinik für Gynäkologie und Geburtshilfe, Universitätsklinikum Schleswig-Holstein, Campus Kiel.
authors.forename: N
authors.initials: N
authors.lastname: Maass
authors.affiliation: Frauenklinik, Klinikum St. Marien, Amberg.
authors.forename: A
authors.initials: A
authors.lastname: Scharl
authors.affiliation: German Breast Group, Neu-Isenburg; Klinik für Gynäkologie und Geburtshilfe, Sana-Klinikum Offenbach, Offenbach.
authors.forename: S
authors.initials: S
authors.lastname: Loibl
keywords: St. Gallen consensus; adjuvant therapy; breast cancer; multigene signatures; neoadjuvant therapy