title: Impact of vessel diameter and bandwidth of illumination in sidestream dark-field oximetry.
abstract: We investigate the possibility of oxygen saturation estimation from images obtained by the sidestream dark-field (SDF) technique. The SDF technique is a method for microvascular imaging. In SDF imaging, light enters a tissue directly from illumination sources configured around a camera and then the camera captures the light scattered by the tissue. To advance the capability of the SDF imaging system, we develop a SDF oximetry method with LED illumination sources. In this paper, we evaluate some SDF oximetry methods from virtual SDF images obtained by the Monte Carlo photon propagation simulation. As a result, we verify that SDF imaging allows the estimation of oxygen saturation of the individual vessels from virtual images using the average extinction coefficients considering the bandwidth of the illumination and the effect of the integration of the camera.
authors.affiliation: Takano Co., Ltd, Nagano, 3994301, Japan ; Graduate School of Engineering, Chiba University, Chiba, 2638522, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kurata
authors.affiliation: Graduate School of Engineering, Chiba University, Chiba, 2638522, Japan.
authors.forename: Zhenguang
authors.initials: Z
authors.lastname: Li
authors.affiliation: Graduate School of Medicine, Chiba University, Chiba, 2608670, Japan.
authors.forename: Shigeto
authors.initials: S
authors.lastname: Oda
authors.affiliation: Center for Frontier Medical Engineering, Chiba University, Chiba, 2638522, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kawahira
authors.affiliation: Center for Frontier Medical Engineering, Chiba University, Chiba, 2638522, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Haneishi
keywords: (170.0170) Medical optics and biotechnology; (170.1470) Blood or tissue constituent monitoring; (170.3660) Light propagation in tissues