title: Incidence, Progression, and Associated Risk Factors of Posterior Vitreous Detachment in Type 2 Diabetes Mellitus: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study (SN-DREAMS II, Report No. 7).
abstract: OBJECTIVE
  To report the incidence and progression of posterior vitreous detachment (PVD) and factors influencing the same in a cohort of patients with type 2 diabetes in a South Indian population.
  
  
  METHODS
  A subset of 615 subjects from Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study II were included in this study. All of the subjects underwent detailed ophthalmic evaluation including stereo fundus photography. The status of PVD was assessed using B-scan ultrasonography. A p value of <0.05 was considered statistically significant.
  
  
  RESULTS
  The incidence of either incomplete PVD (IPVD) or complete PVD (CPVD) from no PVD at baseline visit was 80.8%. Of them, 32.63% converted to CPVD from IPVD at baseline. High prevalence of emmetropia was observed in subjects with stable No PVD. Risk factors associated with the conversion of CPVD from no PVD and IPVD at baseline were age (OR: 1.04, p = 0.002), myopia (OR: 2.14, p = 0.009), and increase in axial length (OR: 1.35, p = 0.004). Subjects undergoing cataract surgery were at 2.32 times higher risk of converting to CPVD (p = 0.038).
  
  
  CONCLUSIONS
  Independent risk factors for the progression of PVD were increase in age, myopia, increased axial length, and cataract surgery.
authors.affiliation: a Elite School of Optometry , Chennai , Tamil Nadu , India.|b Birla Institute of Technology and Science , Pilani , India , and.
authors.forename: Laxmi
authors.initials: L
authors.lastname: Gella
authors.affiliation: c Shri Bhagwan Mahavir Vitreoretinal Services , Chennai , Tamil Nadu , India.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Raman
authors.affiliation: c Shri Bhagwan Mahavir Vitreoretinal Services , Chennai , Tamil Nadu , India.
authors.forename: Swakshyar Saumya
authors.initials: SS
authors.lastname: Pal
authors.affiliation: c Shri Bhagwan Mahavir Vitreoretinal Services , Chennai , Tamil Nadu , India.
authors.forename: Suganeswari
authors.initials: S
authors.lastname: Ganesan
authors.affiliation: c Shri Bhagwan Mahavir Vitreoretinal Services , Chennai , Tamil Nadu , India.
authors.forename: Tarun
authors.initials: T
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058452:Axial Length, Eye / Q000000981:diagnostic imaging*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D003930:Diabetic Retinopathy / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D013997:Time Factors; D020255:Vitreous Detachment / Q000175:diagnosis / Q000453:epidemiology*
keywords: Axial length; cataract surgery; refractive error; sight-threatening diabetic retinopathy; ultrasonography