title: Synthesis and biology of 1,4-benzodioxane lignan natural products.
abstract: Lignan-derived 1,4-benzodioxane natural products have been shown to exhibit a diverse array of biological activities, which has lent them to be the focus of a wealth of synthetic attention. Herein we review the background, bioactivities, biosynthesis and synthetic approaches to the 1,4-benzodioxane lignan scaffold, with an emphasis on 1,4-benzodioxane oxyneolignans.
authors.affiliation: School of Chemical Sciences, University of Auckland, New Zealand. d.barker@auckland.ac.nz.
authors.forename: Lisa I
authors.initials: LI
authors.lastname: Pilkington
authors.forename: David
authors.initials: D
authors.lastname: Barker
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D004146:Dioxanes / Q000138:chemical synthesis* / Q000737:chemistry; D017705:Lignans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D001688:Biological Products; D004146:Dioxanes; D017705:Lignans