title: Physical activity, sedentary behavior and all-cause mortality among blacks and whites with diabetes.
abstract: OBJECTIVE
  The study objective was to examine the role of physical activity (PA) and sedentary time (ST) on mortality risk among a population of low-income adults with diabetes.
  
  
  METHODS
  Black (n = 11,137) and white (n = 4508) men and women with diabetes from the Southern Community Cohort Study self-reported total PA levels and total ST. Participants were categorized into quartiles of total PA and total ST. Hazard ratios (HRs) and 95% confidence intervals (CIs) for subsequent mortality risk were estimated from Cox proportional hazards analysis with adjustment for potential confounders.
  
  
  RESULTS
  During follow-up, 2370 participants died. The multivariable risk of mortality was lower among participants in the highest quartile of PA compared with those in the lowest quartile (HR, 0.64; 95% CI: 0.57-0.73). Mortality risk was significantly increased among participants in the highest compared with the lowest quartile of ST after adjusting for PA (HR, 1.21; 95% CI: 1.08-1.37). Across sex and race groups, similar trends of decreasing mortality with rising PA and increasing mortality with rising ST were observed.
  
  
  CONCLUSIONS
  Although causality cannot be established from these observational data, the current findings suggest that increasing PA and decreasing ST may help extend survival among individuals with diabetes irrespective of race and sex.
authors.affiliation: Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN. Electronic address: kimberly.glenn@tn.gov.
authors.forename: Kimberly R
authors.initials: KR
authors.lastname: Glenn
authors.affiliation: Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN.
authors.forename: James C
authors.initials: JC
authors.lastname: Slaughter
authors.affiliation: Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN.
authors.forename: Jay H
authors.initials: JH
authors.lastname: Fowke
authors.affiliation: Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.
authors.forename: Maciej S
authors.initials: MS
authors.lastname: Buchowski
authors.affiliation: Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
authors.forename: Charles E
authors.initials: CE
authors.lastname: Matthews
authors.affiliation: Department of Epidemiology, Harvard School of Public Health, Boston, MA; Channing Division of Network Medicine, Harvard Medical School, Boston, MA; Dana-Farber/Harvard Cancer Center, Boston, MA.
authors.forename: Lisa B
authors.initials: LB
authors.lastname: Signorello
authors.affiliation: Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN; International Epidemiology Institute, Rockville, MD.
authors.forename: William J
authors.initials: WJ
authors.lastname: Blot
authors.affiliation: Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN.
authors.forename: Loren
authors.initials: L
authors.lastname: Lipworth
mesh_terms: D000328:Adult; D000368:Aged; D044383:Black People / Q000706:statistics & numerical data*; D002318:Cardiovascular Diseases / Q000401:mortality; D003920:Diabetes Mellitus / Q000208:ethnology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009026:Mortality; D009043:Motor Activity; D011203:Poverty; D016016:Proportional Hazards Models; D011446:Prospective Studies; D057185:Sedentary Behavior; D012959:Socioeconomic Factors; D015144:Southeastern United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data*; D001741:Black or African American
keywords: Cardiovascular disease; Diabetes; Low income; Mortality; Physical activity; Sedentary behaviors