title: Two new dammarane-type triterpene sapogenins from Chinese red ginseng.
abstract: Two new dammarane-type triterpene sapogenins were isolated from the Chinese red ginseng. The new sapogenins were named as 24,26-dihydroxy-panaxdiol (1) and 24-hydroxy-panaxdiol (2). Their structures were elucidated by the combined analysis of NMR and mass spectrometry as 20(S),25(R)-epoxydammarane-3β,12β,24β,26-tetraol (1) and 20(S),25-epoxydammarane-3β,12β,24α-triol (2). The complete signal assignments of the two compounds were carried out by 2D NMR spectral and NOE differential spectroscopy analysis.
authors.affiliation: a College of Pharmacy , Jilin University , 126 Xinmin Street, Chaoyang District, Changchun , Jilin CN 130021 , P.R. China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Zheng
authors.affiliation: a College of Pharmacy , Jilin University , 126 Xinmin Street, Chaoyang District, Changchun , Jilin CN 130021 , P.R. China.
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Li
authors.affiliation: a College of Pharmacy , Jilin University , 126 Xinmin Street, Chaoyang District, Changchun , Jilin CN 130021 , P.R. China.
authors.forename: Jinping
authors.initials: J
authors.lastname: Liu
authors.affiliation: a College of Pharmacy , Jilin University , 126 Xinmin Street, Chaoyang District, Changchun , Jilin CN 130021 , P.R. China.
authors.forename: Liu
authors.initials: L
authors.lastname: Han
authors.affiliation: a College of Pharmacy , Jilin University , 126 Xinmin Street, Chaoyang District, Changchun , Jilin CN 130021 , P.R. China.
authors.forename: Nanqi
authors.initials: N
authors.lastname: Zhang
authors.affiliation: a College of Pharmacy , Jilin University , 126 Xinmin Street, Chaoyang District, Changchun , Jilin CN 130021 , P.R. China.
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.affiliation: a College of Pharmacy , Jilin University , 126 Xinmin Street, Chaoyang District, Changchun , Jilin CN 130021 , P.R. China.
authors.forename: Jinluan
authors.initials: J
authors.lastname: Chen
authors.affiliation: a College of Pharmacy , Jilin University , 126 Xinmin Street, Chaoyang District, Changchun , Jilin CN 130021 , P.R. China.
authors.forename: Pingya
authors.initials: P
authors.lastname: Li
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D005894:Panax / Q000737:chemistry*; D012502:Sapogenins / Q000032:analysis* / Q000737:chemistry; D014315:Triterpenes / Q000032:analysis*; D000097669:Dammaranes
chemical_list: D012502:Sapogenins; D014315:Triterpenes; D000097669:Dammaranes
keywords: 20(S),25(R)-epoxydammarane-3β,12β,24β,26-tetraol; 20(S),25-epoxydammarane-3β,12β,24α-triol; Chinese red ginseng; dammarane-type triterpene sapogenin