title: Mast cell/MDSC a liaison immunosuppressive for tumor microenvironment.
abstract: The instauration of an immunosuppressive microenvironment is a key event in cancer development and progression. Here, we discuss increasing evidences of the crosstalk between myeloid-derived suppressor cells (MDSCs) and mast cells (MCs) as a new fuel for the cancer immunosuppressive machinery.
authors.affiliation: Department of Medical and Biological Science; University of Udine ; Udine, Italy ; Inserm UMRS-1149; CNRS ERL 8252; Laboratoire d'excellence INFLAMEX; Université Paris Diderot; Sorbonne Paris Cite ; Paris, France.
authors.forename: Luca
authors.initials: L
authors.lastname: Danelli
authors.affiliation: Department of Medical and Biological Science; University of Udine ; Udine, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Frossi
authors.affiliation: Department of Medical and Biological Science; University of Udine ; Udine, Italy.
authors.forename: Carlo E
authors.initials: CE
authors.lastname: Pucillo
keywords: CD40:CD40L; colon carcinoma; immunosuppression; mast cells; myeloid derived suppressor cells