title: Photo, pH, and thermo triple-responsive spiropyran-based copolymer nanoparticles for controlled release.
abstract: A spiropyran-based amphiphilic random copolymer was synthesized and self-assembled into photo-, pH-, and thermo-responsive micellar nanoparticles. The triple-stimuli triggered morphological changes of the nanoparticles were revealed by TEM and DLS. Highly efficient controlled release of encapsulated molecules, coumarin 102, from the nanoparticles under stimulation of UV light, acid and the combined stimuli could be realized.
authors.affiliation: School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China. guojie.wang@mater.ustb.edu.cn.
authors.forename: Shuo
authors.initials: S
authors.lastname: Chen
authors.forename: Fengjuan
authors.initials: F
authors.lastname: Jiang
authors.forename: Ziquan
authors.initials: Z
authors.lastname: Cao
authors.forename: Guojie
authors.initials: G
authors.lastname: Wang
authors.forename: Zhi-Min
authors.initials: ZM
authors.lastname: Dang
mesh_terms: D000178:Acrylamides / Q000737:chemistry; D001578:Benzopyrans / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry; D000067493:Dynamic Light Scattering; D006863:Hydrogen-Ion Concentration; D007211:Indoles / Q000737:chemistry*; D008823:Micelles; D053758:Nanoparticles / Q000737:chemistry* / Q000378:metabolism / Q000648:ultrastructure; D009574:Nitro Compounds / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013696:Temperature; D014466:Ultraviolet Rays
chemical_list: D000178:Acrylamides; D001578:Benzopyrans; D004337:Drug Carriers; D007211:Indoles; D008823:Micelles; D009574:Nitro Compounds; D011108:Polymers; C088184:spiropyran; C067295:N-isopropylacrylamide