title: Relationship between deficiency of vitamin D and exponents of metabolic syndrome.
abstract: OBJECTIVE
  Widespread hypovitaminosis D and an increased incidence of metabolic syndrome (MetS) represent significant problems of contemporary medicine but link between them remain unresolved. We aimed to define relationship between vitamin D serum concentration and exponents of MetS.
  
  
  METHODS
  The studies were conducted on 70 individuals (51 with and 19 without MetS). Concentrations of 25(OH)D (25-hydroxyergocalciferol and 25-hydroxycholecalciferol), calcium, cholesterol, HDL, cholesterol LDL, triglycerides, fasting glucose, blood pressure and anthropometric parameters were measured.
  
  
  RESULTS
  Median concentration of vitamin D in the research population amounted to 41.46 nmol/L. Concentration of 25(OH)D in MetS group was lower than in remainder participants (38.45 nmol/L vs. 58.50 nmol/L, p = 0.0104). An inverse correlation was demonstrated between 25(OH)D level on one hand and body weight, waist and hips circumference, adipose body weight, Body Mass Index, Waist to Height Ratio (WHtR), glycaemia and number of MetS components on the other in persons free of MetS. No such relationships could be documented in MetS group. In the entire population values of Waist to Hip Ratio (WHpR) and WHtR indices manifested correlation with hyperglycaemia, hypertriglyceridaemia, low HDL concentrations.
  
  
  CONCLUSIONS
  In persons without MetS a relationship was detected between vitamin D concentration and exponents of metabolic syndrome, although further studies on this problem are required.
authors.affiliation: Division of Biology of Civilization-Linked Diseases, Department of Chemistry and Clinical Biochemistry, Poznan University of Medical Sciences, Poznan, Poland. mkramkowska@ump.edu.pl.
authors.forename: M
authors.initials: M
authors.lastname: Kramkowska
authors.forename: T
authors.initials: T
authors.lastname: Grzelak
authors.forename: M
authors.initials: M
authors.lastname: Walczak
authors.forename: P
authors.initials: P
authors.lastname: Bogdanski
authors.forename: D
authors.initials: D
authors.lastname: Pupek-Musialik
authors.forename: K
authors.initials: K
authors.lastname: Czyzewska
mesh_terms: D050154:Adiposity / Q000502:physiology; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight / Q000502:physiology; D008078:Cholesterol, LDL / Q000097:blood; D003430:Cross-Sectional Studies; D005215:Fasting / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000175:diagnosis* / Q000453:epidemiology; D008875:Middle Aged; D012307:Risk Factors; D014807:Vitamin D / Q000097:blood*; D014808:Vitamin D Deficiency / Q000097:blood* / Q000175:diagnosis* / Q000453:epidemiology
chemical_list: D001786:Blood Glucose; D008078:Cholesterol, LDL; D014807:Vitamin D