title: Microscope-integrated optical coherence tomography for image-aided positioning of glaucoma surgery.
abstract: Most glaucoma surgeries involve creating new aqueous outflow pathways with the use of a small surgical instrument. This article reported a microscope-integrated, real-time, high-speed, swept-source optical coherence tomography system (SS-OCT) with a 1310-nm light source for glaucoma surgery. A special mechanism was designed to produce an adjustable system suitable for use in surgery. A two-graphic processing unit architecture was used to speed up the data processing and real-time volumetric rendering. The position of the surgical instrument can be monitored and measured using the microscope and a grid-inserted image of the SS-OCT. Finally, experiments were simulated to assess the effectiveness of this integrated system. Experimental results show that this system is a suitable positioning tool for glaucoma surgery.
authors.affiliation: Chinese Academy of Sciences, Key Laboratory on Adaptive Optics, Chengdu 610209, ChinabChinese Academy of Sciences, Institute of Optics and Electronics, P.O. Box 350, Shuangliu, Sichuan, Chengdu 610209, China.
authors.forename: Xiqi
authors.initials: X
authors.lastname: Li
authors.affiliation: Chinese Academy of Sciences, Key Laboratory on Adaptive Optics, Chengdu 610209, ChinabChinese Academy of Sciences, Institute of Optics and Electronics, P.O. Box 350, Shuangliu, Sichuan, Chengdu 610209, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Wei
authors.affiliation: Peking University Third Hospital, Department of Ophthalmology, Beijing 100191, China.
authors.forename: Xuechuan
authors.initials: X
authors.lastname: Dong
authors.affiliation: Peking University Third Hospital, Department of Ophthalmology, Beijing 100191, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Huang
authors.affiliation: Peking University Third Hospital, Department of Ophthalmology, Beijing 100191, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Chinese Academy of Sciences, Key Laboratory on Adaptive Optics, Chengdu 610209, ChinabChinese Academy of Sciences, Institute of Optics and Electronics, P.O. Box 350, Shuangliu, Sichuan, Chengdu 610209, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: He
authors.affiliation: Chinese Academy of Sciences, Key Laboratory on Adaptive Optics, Chengdu 610209, ChinabChinese Academy of Sciences, Institute of Optics and Electronics, P.O. Box 350, Shuangliu, Sichuan, Chengdu 610209, China.
authors.forename: Guohua
authors.initials: G
authors.lastname: Shi
authors.affiliation: Chinese Academy of Sciences, Key Laboratory on Adaptive Optics, Chengdu 610209, ChinabChinese Academy of Sciences, Institute of Optics and Electronics, P.O. Box 350, Shuangliu, Sichuan, Chengdu 610209, China.
authors.forename: Yudong
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D004867:Equipment Design; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D008853:Microscopy / Q000379:methods*; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D025321:Surgery, Computer-Assisted / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*