title: Rapidly enlarging low-grade fibromyxoid sarcoma with intracranial extension in a 5-year-old girl: case report.
abstract: Low-grade fibromyxoid sarcoma (LGFMS) is a rare mesenchymal tumor that is characterized by a benign histology but potentially aggressive clinical behavior, with a high rate of recurrence and metastasis. It primarily occurs in young adults in the extremities, inguinal area, neck, or chest wall. There are rare reports of intracranial LGFMS in adults. In this report, the authors present the case of a 5-year-old girl who presented with a rapidly enlarging frontal scalp mass. Pathological examination of the resected mass demonstrated LGFMS. To the authors' knowledge, this is the only reported case of intracranial LGFMS in a child.
authors.affiliation: Departments of 1 Neurological Surgery and.
authors.forename: Ian K
authors.initials: IK
authors.lastname: White
authors.affiliation: Departments of 1 Neurological Surgery and.
authors.forename: Andrea G
authors.initials: AG
authors.lastname: Scherer
authors.affiliation: Departments of 1 Neurological Surgery and.
authors.forename: Maraya M
authors.initials: MM
authors.lastname: Baumanis
authors.affiliation: Pathology and Laboratory Medicine, Indiana University School of Medicine; and.
authors.forename: Marwah
authors.initials: M
authors.lastname: Abdulkader
authors.affiliation: Department of Neurological Surgery, Division of Pediatric Neurosurgery, Goodman Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Fulkerson
mesh_terms: D002675:Child, Preschool; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D005354:Fibrosarcoma / Q000473:pathology*; D005625:Frontal Lobe / Q000473:pathology*; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D009361:Neoplasm Invasiveness / Q000473:pathology; D012074:Remission Induction; D012535:Scalp / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D047368:Tumor Burden
keywords: LGFMS = low-grade fibromyxoid sarcoma; PDGF = platelet-derived growth factor; brain tumor; fibromyxoid sarcoma; mesenchymal; oncology; pediatric