title: Calcium Sensing in the Renal Tubule.
abstract: In addition to its prominent role in the parathyroid gland, the calcium-sensing receptor (CaSR) is expressed in various tissues, including the kidney. This article reviews current data on the calcium-sensing properties of the kidney, the localization of the CaSR protein along the nephron, and its function in calcium homeostasis and in hypercalciuria.
authors.affiliation: Division of Nephrology and Hypertension, Eastern Virginia Medical School, Norfolk, Virginia; Division of Nephrology, Beth Israel Deaconess Medical Center, Boston, Massachussetts; and.
authors.forename: Hakan R
authors.initials: HR
authors.lastname: Toka
authors.affiliation: Division of Nephrology, Beth Israel Deaconess Medical Center, Boston, Massachussetts; and.
authors.forename: Martin R
authors.initials: MR
authors.lastname: Pollak
authors.affiliation: Université Paris-Descartes, Sorbonne Paris-Cité, Centre de Recherche des Cordeliers, INSERM UMRS 1138, Service de Physiologie, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France pascal.houillier@inserm.fr.
authors.forename: Pascal
authors.initials: P
authors.lastname: Houillier
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D006706:Homeostasis; D006801:Humans; D053565:Hypercalciuria / Q000378:metabolism / Q000503:physiopathology; D007684:Kidney Tubules / Q000378:metabolism* / Q000503:physiopathology; D044169:Receptors, Calcium-Sensing / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D044169:Receptors, Calcium-Sensing; D002118:Calcium