title: Negative epistasis: a route to intraspecific reproductive isolation in yeast?
abstract: Exploring the molecular bases of intraspecific reproductive isolation captures the ongoing phenotypic consequences of genetic divergence and provides insights into the early onset of speciation. Recent species-wide surveys using natural populations of yeasts demonstrated that intrinsic post-zygotic reproductive isolation segregates readily within the same species, and revealed the multiplicity of the genetic mechanisms underlying such processes. These advances deepened our current understandings and opened further perspectives regarding the complete picture of molecular and evolutionary origins driving the onset of intraspecific reproductive isolation in yeasts.
authors.affiliation: Department of Genetics, Genomics and Microbiology, University of Strasbourg / CNRS, UMR7156, Strasbourg, France.
authors.forename: Jing
authors.initials: J
authors.lastname: Hou
authors.affiliation: Department of Genetics, Genomics and Microbiology, University of Strasbourg / CNRS, UMR7156, Strasbourg, France. schacherer@unistra.fr.
authors.forename: Joseph
authors.initials: J
authors.lastname: Schacherer
mesh_terms: D004777:Environment; D004843:Epistasis, Genetic; D060047:Reproductive Isolation; D012441:Saccharomyces cerevisiae / Q000502:physiology; D015003:Yeasts / Q000502:physiology*
keywords: Epistatic interaction; Genetic incompatibility; Intraspecific diversity; Reproductive isolation; Saccharomyces cerevisiae; Yeast