title: Influence of polyethylene microplastic beads on the uptake and localization of silver in zebrafish (Danio rerio).
abstract: This study aimed to determine whether the uptake and localization of Ag in zebrafish was affected by the presence of polyethylene microplastic beads (PE MPBs). Zebrafish were exposed to 1 μg Ag L(-1) (radiolabelled with (110m)Ag) for 4 and 24 h in the presence or absence of PE MPBs (10, 100 or 1000 MPBs mL(-1)), and one treatment in which MPBs (1000 MPBs mL(-1)) were incubated with Ag to promote adsorption. The presence of MPBs, at any of the tested doses, had no effect on the uptake or localization of Ag. However, exposure to the Ag-incubated MPBs (∽75% of the Ag bound to MPBs) significantly reduced Ag uptake at both time points and also significantly increased the proportion of intestinal Ag. This study demonstrates that microplastics can alter the bioavailability and uptake route of a metal contaminant in a model fish species.
authors.affiliation: Department of Environmental, Social and Spatial Change (ENSPAC), Roskilde University, Universitetsvej 1, PO Box 260, DK-4000, Roskilde, Denmark. Electronic address: frkhan@ruc.dk.
authors.forename: Farhan R
authors.initials: FR
authors.lastname: Khan
authors.affiliation: Department of Environmental, Social and Spatial Change (ENSPAC), Roskilde University, Universitetsvej 1, PO Box 260, DK-4000, Roskilde, Denmark.
authors.forename: Kristian
authors.initials: K
authors.lastname: Syberg
authors.affiliation: Department of Conservation, National Museum of Denmark, Brede, 2800, Kongens Lyngby, Denmark.
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Shashoua
authors.affiliation: Nutritional Sciences Division, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, United Kingdom.
authors.forename: Nicolas R
authors.initials: NR
authors.lastname: Bury
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D020959:Polyethylene / Q000494:pharmacology*; D012834:Silver / Q000378:metabolism*; D015027:Zebrafish / Q000378:metabolism*
chemical_list: D012834:Silver; D020959:Polyethylene
keywords: Adsorbed pollutants; Dietary metal; Microplastics; Scrubbers; Vector-effect