title: Chronic inflammation in endometriosis and endometriosis-associated ovarian cancer: New roles for the "old" complement pathway.
abstract: Immune escape is consequential for cancer development. Identifying abnormalities of the immune microenvironment during early carcinogenesis can provide insight into disease pathogenesis and unravel new preventive or therapeutic targets. We recently conducted a comprehensive immune gene expression analysis in endometriosis and endometriosis-associated ovarian cancer and explored new mechanistic roles for the complement pathway.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences; University of Pittsburgh School of Medicine and Magee Women's Research Institute (MWRI) ; Pittsburgh, PA USA ; Magee-Womens Hospital of University of Pittsburgh Medical Center ; Pittsburgh, PA USA.
authors.forename: Robert P
authors.initials: RP
authors.lastname: Edwards
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences; University of Pittsburgh School of Medicine and Magee Women's Research Institute (MWRI) ; Pittsburgh, PA USA.
authors.forename: Xin
authors.initials: X
authors.lastname: Huang
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences; University of Pittsburgh School of Medicine and Magee Women's Research Institute (MWRI) ; Pittsburgh, PA USA.
authors.forename: Anda M
authors.initials: AM
authors.lastname: Vlad
keywords: atypical endometriosis; complement; endometriosis; endometriosis-associated ovarian cancer