title: Lip Repair Surgery for Bilateral Cleft Lip and Palate in a Patient Diagnosed with Trisomy 13 and Holoprosencephaly.
abstract: We report a case of lip repair surgery performed for bilateral cleft lip and palate in a patient diagnosed with trisomy 13 and holoprosencephaly. At the age of 2 years and 7 months, the surgery was performed using a modified De Hann design under general anesthesia. The operation was completed in 1 h and 21 min without large fluctuations in the child's general condition. The precise measurement of the intraoperative design was omitted, and the operation was completed using minimal skin sutures. It is possible to perform less-invasive and short surgical procedures after careful consideration during the preoperative planning. Considering the recent improvements in the life expectancy of patients with trisomy 13, we conclude that surgical treatments for non-life threatening malformations such as cleft lip and palate should be performed for such patients.
authors.affiliation: Department of Plastic Surgery, Tokai University, School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. akamatu@is.icc.u-tokai.ac.jp.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Akamatsu
authors.forename: Ushio
authors.initials: U
authors.lastname: Hanai
authors.forename: Serina
authors.initials: S
authors.lastname: Nakajima
authors.forename: Megumi
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Muneo
authors.initials: M
authors.lastname: Miyasaka
authors.forename: Shinichi
authors.initials: S
authors.lastname: Matsuda
authors.forename: Mariko
authors.initials: M
authors.lastname: Ikegami
mesh_terms: D000015:Abnormalities, Multiple / Q000601:surgery*; D000768:Anesthesia, General; D002675:Child, Preschool; D025063:Chromosome Disorders / Q000150:complications*; D002882:Chromosomes, Human, Pair 13; D002971:Cleft Lip / Q000150:complications* / Q000601:surgery; D002972:Cleft Palate / Q000150:complications* / Q000601:surgery; D062109:Dermatologic Surgical Procedures / Q000379:methods*; D005260:Female; D016142:Holoprosencephaly / Q000150:complications*; D006801:Humans; D008046:Lip / Q000601:surgery; D061646:Operative Time; D010347:Patient Care Planning; D011300:Preoperative Care; D019651:Plastic Surgery Procedures / Q000379:methods*; D013518:Surgery, Plastic / Q000379:methods*; D013536:Suture Techniques; D016896:Treatment Outcome; D014314:Trisomy; D000073839:Trisomy 13 Syndrome