title: Fluorescent Probes for H2S Detection and Quantification.
abstract: Many diverse, sensitive and structurally novel fluorescent probes have recently been reported for H2S detection. Quantification of H2S requires a selective chemosensor which will react only with H2S against a background of high concentrations of other thiols or reducing agents. Most published probes are able to quantify H2S selectively in a simple in vitro system with the most sensitive probes able to detect H2S at below 100 nM concentrations. A subset of probes also have utility in sensing H2S in living cells, and there are now several with specific sub-cellular localization and a few cases of in vivo applications. Biologists studying H2S now have a wide range of tools to assist them to aid further understanding of the role of H2S in biology.
authors.affiliation: Department of Pharmacy, National University of Singapore, Block S4A #03, 18 Science Drive 4, Singapore, 117543, Singapore.
authors.forename: Wei
authors.initials: W
authors.lastname: Feng
authors.forename: Brian W
authors.initials: BW
authors.lastname: Dymock
mesh_terms: D005456:Fluorescent Dyes; D006801:Humans; D006862:Hydrogen Sulfide / Q000032:analysis*
chemical_list: D005456:Fluorescent Dyes; D006862:Hydrogen Sulfide