title: [Management of bleeding and coagulopathy following major trauma].
abstract: Bleeding is the most common preventable cause of death in trauma patients. Acute traumatic coagulopathy is a specific condition with a different pathophysiology from other causes of the massive bleeding. An early identification of the coagulopathy is fundamental to implementing rapid treatment. There have been many changes in the management of massive hemorrhage, for example, the administration of the tranexamic acid and the use of balanced transfusion ratio. This review presents these practical points, some of them with scientific evidence, in order to achieve a beneficial effect for patient outcomes.
authors.affiliation: Servicio de Anestesiología y Reanimación, Complexo Hospitalario Universitario de A Coruña, La Coruña, España. Electronic address: etxanizalvarez@hotmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Etxaniz
authors.affiliation: Servicio de Anestesiología y Reanimación, Complexo Hospitalario Universitario de A Coruña, La Coruña, España.
authors.forename: E
authors.initials: E
authors.lastname: Pita
mesh_terms: D001778:Blood Coagulation Disorders / Q000188:drug therapy; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D009104:Multiple Trauma; D014148:Tranexamic Acid / Q000627:therapeutic use; D065227:Transfusion Reaction
chemical_list: D014148:Tranexamic Acid
keywords: Fibrinogen; Fibrinógeno; Haemorrhage; Hemorragia; Medicina transfusional; Tranexamic acid; Transfusion medicine; Ácido tranexámico