title: Granulomatous Vasculitis.
abstract: Vasculitides are uncommon disorders, characterized by inflammation of the blood vessels resulting either in ischemia or hemorrhage. They are commonly classified as small-, medium-, or large-vessel vasculitides. Antineutrophil cytoplasmic antibody-associated vasculitis is an important group of small-vessel vasculitis. This group includes granulomatous vasculitides, namely, granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and nongranulomatous vasculitis, namely, microscopic polyangiitis (MPA). Classic polyarteritis nodosa (PAN) is a granulomatous medium-vessel vasculitis. This review discusses the classification, etiopathogenesis, clinical features, and management of GPA, MPA, EGPA and PAN.
authors.affiliation: Rheumatology Division, Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address: amansharma74@yahoo.com.
authors.forename: Aman
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Department of Dermatology, Venereology and Leperology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Dogra
authors.affiliation: Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Kusum
authors.initials: K
authors.lastname: Sharma
mesh_terms: D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000175:diagnosis / Q000188:drug therapy; D015267:Churg-Strauss Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D055953:Microscopic Polyangiitis / Q000175:diagnosis* / Q000188:drug therapy; D010488:Polyarteritis Nodosa / Q000175:diagnosis* / Q000188:drug therapy; D012867:Skin / Q000473:pathology*
chemical_list: D007166:Immunosuppressive Agents
keywords: Cutaneous polyarteritis nodosa; Eosinophilic granulomatosis with polyangiitis; Granulomatosis with polyangiitis; Microscopic polyangiitis; Polyarteritis nodosa