title: Chyluria: a scourge of our region.
abstract: Chyluria is endemic in the Gangetic belt of India with an average of 90 cases treated annually at our institute. It is almost exclusively caused by Wuchereria bancrofti in tropical areas. Chylomicrons and triglycerides are lost in the urine from an abnormal lymphourinary fistula due to obstructive lymphatic stasis, most commonly at the renal pelvis. It is a distressingly recurrent condition with multiple exacerbations and remissions over years. Severe weakness, weight loss and haematuria occur in some patients. Diagnosis can be made by visual examination of milky urine along with the ether test of urine for chylomicrons. Intravenous urography is used to locate the site of the fistula, although the detection rate is poor. Treatment starts with conservative measures such as a high-protein low-fat diet and diethylcarbamazine therapy. In cases where conservative measures fail, endoscopic sclerotherapy (renal pelvic instillation of silver nitrate, povidone iodine or others) and surgical therapy are used.
authors.affiliation: Department of Urology, CNMCH, Kolkata, West Bengal, India.
authors.forename: Rajan Kumar
authors.initials: RK
authors.lastname: Sinha
authors.affiliation: Department of Urology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
authors.forename: Nikhil
authors.initials: N
authors.lastname: Ranjan
authors.affiliation: Department of Pathology, NSCB Medical College, Jabalpur, Madhya Pradesh, India.
authors.forename: Neha
authors.initials: N
authors.lastname: Singh
authors.affiliation: Department of Surgery, SRMS-IMS, Bareilly, Uttar Pradesh, India.
authors.forename: Keshri
authors.initials: K
authors.lastname: Amit
mesh_terms: D000328:Adult; D000818:Animals; D002913:Chyle / Q000469:parasitology*; D018752:Diet, Fat-Restricted; D005260:Female; D006417:Hematuria / Q000209:etiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D007682:Kidney Pelvis / Q000469:parasitology / Q000473:pathology*; D008206:Lymphatic Diseases / Q000175:diagnosis* / Q000628:therapy / Q000652:urine; D057147:Mosquito Nets / Q000706:statistics & numerical data; D010353:Patient Education as Topic; D015911:Sclerotherapy / Q000379:methods*; D016896:Treatment Outcome; D014567:Urography; D014958:Wuchereria bancrofti / Q000302:isolation & purification*