title: Highly-efficient T4 DNA ligase-based SNP analysis using a ligation fragment containing a modified nucleobase at the end.
abstract: A highly accurate ligase-based SNP analysis was developed by using modified base-end downstream ligation fragments as detection probes, which can clearly distinguish C/T SNP types without any "false-positive" results.
authors.affiliation: Department of Biotechnology and Bioinformatics, Korea University, Jochiwon, Sejong 339-700, Korea. spack@korea.ac.kr.
authors.forename: Eui Kyoung
authors.initials: EK
authors.lastname: Jang
authors.forename: Munhee
authors.initials: M
authors.lastname: Yang
authors.forename: Seung Pil
authors.initials: SP
authors.lastname: Pack
mesh_terms: D017122:Bacteriophage T4 / Q000201:enzymology*; D001483:Base Sequence; D004247:DNA / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D011088:DNA Ligases / Q000378:metabolism*; D020641:Polymorphism, Single Nucleotide
chemical_list: D004247:DNA; D011088:DNA Ligases