title: Idiopathic Ophthalmodynia and Idiopathic Rhinalgia: A Prospective Series of 16 New Cases.
abstract: BACKGROUND
  Idiopathic ophthalmodynia and idiopathic rhinalgia were described a few years ago. These conditions seem specific pain syndromes with a distinctive location in the eye or in the nose. We aimed to present a new prospective series in order to verify the consistency of these syndromes.
  
  
  METHODS
  We performed a descriptive study of all patients referred to our regional neurologic clinics from 2010 to 2014 because of facial pain exclusively felt in the eye or in the nose fulfilling the proposed diagnostic criteria for idiopathic ophthalmodynia and idiopathic rhinalgia.
  
  
  RESULTS
  There were 9 patients with idiopathic ophthalmodynia and 7 patients with idiopathic rhinalgia, with a clear female preponderance, and a mean age at onset in the fifth decade. The pain was usually moderate and the temporal pattern was generally chronic. Only one patient reported accompaniments (hypersensitivity to the light and to the flow of air in the symptomatic eye). Preventive treatment with amitriptyline, pregabalin, or gabapentin was partially or totally effective.
  
  
  CONCLUSIONS
  The clinical features of this new series parallels those of the original description, thus indicating that both idiopathic ophthalmodynia and idiopathic rhinalgia have clear-cut clinical pictures with excellent consistency both inter- and intra-individually.
authors.affiliation: Neurology Department of University Hospital Fundación Alcorcón, Madrid, Spain.
authors.forename: Juan A
authors.initials: JA
authors.lastname: Pareja
authors.affiliation: Neurology Department of University Hospital Fundación Alcorcón, Madrid, Spain.
authors.forename: Teresa
authors.initials: T
authors.lastname: Montojo
authors.affiliation: Neurology Department of Hospital Clínico Universitario, Valladolid, Spain.
authors.forename: Ángel L
authors.initials: ÁL
authors.lastname: Guerrero
authors.affiliation: Neurology Department of University Hospital Fundación Alcorcón, Madrid, Spain.
authors.forename: Mónica
authors.initials: M
authors.lastname: Álvarez
authors.affiliation: Neurology Department of Hospital Clínico San Carlos, Medicine Department of Universidad Complutense, Madrid, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Porta-Etessam
authors.affiliation: Neurology Department of Hospital Clínico San Carlos, Medicine Department of Universidad Complutense, Madrid, Spain.
authors.forename: María L
authors.initials: ML
authors.lastname: Cuadrado
mesh_terms: D000328:Adult; D000368:Aged; D000588:Amines / Q000008:administration & dosage; D003509:Cyclohexanecarboxylic Acids / Q000008:administration & dosage; D058447:Eye Pain / Q000175:diagnosis* / Q000517:prevention & control*; D005157:Facial Pain / Q000175:diagnosis* / Q000517:prevention & control*; D005260:Female; D000077206:Gabapentin; D006801:Humans; D008297:Male; D008875:Middle Aged; D009666:Nose / Q000473:pathology*; D065129:Pre-Exposure Prophylaxis / Q000379:methods*; D011446:Prospective Studies; D055815:Young Adult; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage
chemical_list: D000588:Amines; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin
keywords: burning mouth syndrome; idiopathic ophthalmodynia; idiopathic rhinalgia; persistent idiopathic facial pain