title: Pulmonar recruitment in acute respiratory distress syndrome. What is the best strategy?
abstract: Supporting patients with acute respiratory distress syndrome (ARDS), using a protective mechanical ventilation strategy characterized by low tidal volume and limitation of positive end-expiratory pressure (PEEP) is a standard practice in the intensive care unit. However, these strategies can promote lung de-recruitment, leading to the cyclic closing and reopening of collapsed alveoli and small airways. Recruitment maneuvers (RM) can be used to augment other methods, like positive end-expiratory pressure and positioning, to improve aerated lung volume. Clinical practice varies widely, and the optimal method and patient selection for recruitment maneuvers have not been determined, considerable uncertainty remaining regarding the appropriateness of RM. This review aims to discuss recent findings about the available types of RM, and compare the effectiveness, indications and adverse effects among them, as well as their impact on morbidity and mortality in ARDS patients. Recent developments include experimental and clinical evidence that a stepwise extended recruitment maneuver may cause an improvement in aerated lung volume and decrease the biological impact seen with the traditionally used sustained inflation, with less adverse effects. Prone positioning can reduce mortality in severe ARDS patients and may be an useful adjunct to recruitment maneuvers and advanced ventilatory strategies, such noisy ventilation and BIVENT, which have been useful in providing lung recruitment.
authors.affiliation: Faculty of Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Cíntia Lourenço
authors.initials: CL
authors.lastname: Santos
authors.affiliation: Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Brasil.
authors.forename: Cynthia dos Santos
authors.initials: Cdos S
authors.lastname: Samary
authors.affiliation: Universidade Federal de Lavras, Lavras, Minas Gerais, Brazil.
authors.forename: Pedro Laurindo
authors.initials: PL
authors.lastname: Fiorio Júnior
authors.affiliation: Universidade Estacio de Sá, Rio de Janeiro, Brasil.
authors.forename: Bruna Lourenço
authors.initials: BL
authors.lastname: Santos
authors.affiliation: Department of Surgery, Faculty of Medicine, Universidade Federal do Rio de Janeiro, Brasil.
authors.forename: Alberto
authors.initials: A
authors.lastname: Schanaider
mesh_terms: D006801:Humans; D012121:Respiration, Artificial / Q000379:methods; D012128:Respiratory Distress Syndrome / Q000628:therapy*