title: The Predictor of Mortality within Six-Months in Patients with Spontaneous Cerebellar Hemorrhage: A Retrospective Study.
abstract: OBJECTIVE
  The mortality rate of cerebellar hemorrhage (CH) is generally higher than other types of intracranial hemorrhage. Recently, the increased survey rate of CH has come from improved clinical imaging and earlier surgical intervention. Hence, the predictors of intermittent- (1 to 6 months) and long-term (> 6 months) mortality are clinically practical use for educational and therapeutic decisions. Unfortunately, the factors predictive mortality within six-month had not yet been systematically investigated.
  
  
  METHODS
  Seventy-two patients with acute spontaneous CH were retrospectively analyzed. The patients were divided into the six-month mortality group (n = 21, died within 6 months after CH onset) and survival group (n = 51, survived beyond 6 months). The independent predictors of six-month mortality were investigated by multivariate Cox proportional hazards regression.
  
  
  RESULTS
  The radiological brainstem compression (hazard ratios = 23.5; p < 0.001) was independent predictor of mortality within six-month after CH onset. The median onset time of six-month mortality was 5 days in patients with brainstem compression (p < 0.001) and the hazard ratios for the onset time was 13.1 compared with those without brainstem compression (95% CI, 4.7 to 36.3, p < 0.001).
  
  
  CONCLUSIONS
  We report the first study that radiological brainstem compression predicted the mortality within six-month after onset of CH. Patients with radiological brainstem compression were about 23 times more likely to die within 6 months after CH than those without radiological brainstem compression.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, No. 325, Sec. 2, Neihu District, Taipei, Taiwan; Department of Physical Medicine and Rehabilitation, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Chih-Ya
authors.initials: CY
authors.lastname: Chang
authors.affiliation: Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, No. 325, Sec. 2, Neihu District, Taipei, Taiwan; Department of Physical Medicine and Rehabilitation, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Ching-Yueh
authors.initials: CY
authors.lastname: Lin
authors.affiliation: Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, No. 325, Sec. 2, Neihu District, Taipei, Taiwan; Department of Physical Medicine and Rehabilitation, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Liang-Cheng
authors.initials: LC
authors.lastname: Chen
authors.affiliation: Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, No. 325, Sec. 2, Neihu District, Taipei, Taiwan; Department of Physical Medicine and Rehabilitation, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Chia-Hung
authors.initials: CH
authors.lastname: Sun
authors.affiliation: Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, No. 325, Sec. 2, Neihu District, Taipei, Taiwan; Department of Physical Medicine and Rehabilitation, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Tsung-Ying
authors.initials: TY
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Tung-Han
authors.initials: TH
authors.lastname: Tsai
authors.affiliation: Department of Physical Medicine and Rehabilitation, School of Medicine, National Defense Medical Center, Taipei, Taiwan; Department of Rehabilitation, Taichung Veterans General Hospital, Taichung, Taiwan.
authors.forename: Shin-Tsu
authors.initials: ST
authors.lastname: Chang
authors.affiliation: Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, No. 325, Sec. 2, Neihu District, Taipei, Taiwan; Department of Physical Medicine and Rehabilitation, School of Medicine, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Yung-Tsan
authors.initials: YT
authors.lastname: Wu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000209:etiology / Q000401:mortality*; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000175:diagnosis / Q000209:etiology / Q000401:mortality*; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors