title: Therapeutic Targets for Cerebral Ischemia Based on the Signaling Pathways of the GluN2B C Terminus.
authors.affiliation: From the Department of Pharmacy (Y.S., Y.C., L. Zhan, Z.G.), Hebei Research Center of Pharmaceutical and Chemical Engineering (Y.S., Z.G.), and State Key Laboratory Breeding Base-Hebei Province Key Laboratory of Molecular Chemistry for Drug (Z.G.), Hebei University of Science and Technology, Shijiazhuang, China; and Department of Pathophysiology, Hebei Medical University, Shijiazhuang, China (L. Zhang).
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Sun
authors.affiliation: From the Department of Pharmacy (Y.S., Y.C., L. Zhan, Z.G.), Hebei Research Center of Pharmaceutical and Chemical Engineering (Y.S., Z.G.), and State Key Laboratory Breeding Base-Hebei Province Key Laboratory of Molecular Chemistry for Drug (Z.G.), Hebei University of Science and Technology, Shijiazhuang, China; and Department of Pathophysiology, Hebei Medical University, Shijiazhuang, China (L. Zhang).
authors.forename: Linan
authors.initials: L
authors.lastname: Zhang
authors.affiliation: From the Department of Pharmacy (Y.S., Y.C., L. Zhan, Z.G.), Hebei Research Center of Pharmaceutical and Chemical Engineering (Y.S., Z.G.), and State Key Laboratory Breeding Base-Hebei Province Key Laboratory of Molecular Chemistry for Drug (Z.G.), Hebei University of Science and Technology, Shijiazhuang, China; and Department of Pathophysiology, Hebei Medical University, Shijiazhuang, China (L. Zhang).
authors.forename: You
authors.initials: Y
authors.lastname: Chen
authors.affiliation: From the Department of Pharmacy (Y.S., Y.C., L. Zhan, Z.G.), Hebei Research Center of Pharmaceutical and Chemical Engineering (Y.S., Z.G.), and State Key Laboratory Breeding Base-Hebei Province Key Laboratory of Molecular Chemistry for Drug (Z.G.), Hebei University of Science and Technology, Shijiazhuang, China; and Department of Pathophysiology, Hebei Medical University, Shijiazhuang, China (L. Zhang).
authors.forename: Liying
authors.initials: L
authors.lastname: Zhan
authors.affiliation: From the Department of Pharmacy (Y.S., Y.C., L. Zhan, Z.G.), Hebei Research Center of Pharmaceutical and Chemical Engineering (Y.S., Z.G.), and State Key Laboratory Breeding Base-Hebei Province Key Laboratory of Molecular Chemistry for Drug (Z.G.), Hebei University of Science and Technology, Shijiazhuang, China; and Department of Pathophysiology, Hebei Medical University, Shijiazhuang, China (L. Zhang). sunyongjun@hebust.edu.cn.
authors.forename: Zibin
authors.initials: Z
authors.lastname: Gao
mesh_terms: D002545:Brain Ischemia / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism*; D016503:Drug Delivery Systems / Q000379:methods*; D018683:Excitatory Amino Acid Agents / Q000008:administration & dosage / Q000378:metabolism; D006801:Humans; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects* / Q000502:physiology
chemical_list: D018683:Excitatory Amino Acid Agents; C121001:NR2B NMDA receptor; D016194:Receptors, N-Methyl-D-Aspartate
keywords: GluN2B-containing NMDA receptor; PTEN protein; brain ischemia; calcium-calmodulin-dependent protein kinase type 2; death-associated protein kinases; nitric oxide synthase type I