title: Epidemiology of Moyamoya Disease in Korea: Based on National Health Insurance Service Data.
abstract: There have been a few studies reporting the epidemiology of moyamoya disease in Korea. Previous studies revealed relatively high prevalence and incidence of moyamoya disease in Korea and Japan. This study was designed to provide the latest epidemiologic information of moyamoya disease in Korea. We analyzed a database comprising of 50 million people covered in Korea by the National Health Insurance Service to calculate the prevalence. The incidence was estimated by eliminating the duplicated records of previous 3 years. We summarized the prevalence and incidence according to age, sex, and local distribution. In addition, the chronological changes were demonstrated with direct standardization using the 2010 population structure information. The standardized prevalence was 6.5 per 100000 persons in 2005, which was increased to 18.1 in 2013. In the same period, standardized incidence was increased from 2.7 to 4.3 per 100000 persons. The prevalence for men was 4.9 and 8.3 for women in 2005. In 2013, the prevalence had increased for men and women to 13.8 and 25.3, respectively. The incidence for men and women was 2.2 and 3.2, respectively, in 2005. It had increased to 3.5 and 5.7, respectively. The mean age of patients was 33.5 in 2005 and increased to 42.5 in 2013. The peak prevalent age group had shifted slightly to the older age groups, with chronologically consistent female predominance. The prevalence was highest in Jeollabuk province and lowest in Ulsan city.
authors.affiliation: Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Tackeun
authors.initials: T
authors.lastname: Kim
authors.affiliation: Center for Preventive Medicine and Public Health, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Heeyoung
authors.initials: H
authors.lastname: Lee
authors.affiliation: Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Jae Seung
authors.initials: JS
authors.lastname: Bang
authors.affiliation: Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: O-Ki
authors.initials: OK
authors.lastname: Kwon
authors.affiliation: Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Gyojun
authors.initials: G
authors.lastname: Hwang
authors.affiliation: Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Chang Wan
authors.initials: CW
authors.lastname: Oh
keywords: Epidemiology; Korea; Moyamoya disease