title: The Impact of Clinical Pharmacist Support on Patients Receiving Multi-drug Therapy for Coronary Heart Disease in China.
abstract: The study determined pharmacist support on patients receiving multi-drug therapy for coronary heart disease by evaluating patient self-care ability, quality of life, and drug therapy compliance. In this study, ninety patients were randomly assigned to an experimental group (n=45) and a control group (n=45). The control group received conventional clinical care. The experimental group received clinical care plus pharmacist support that included medication review, patient education, lifestyle management, discharge guidance, and telephone follow-up. Eighty-five patients completed the study. Self-care ability and quality of life were evaluated before hospital discharge. The experimental group understood their condition better than the control group (P<0.05), the differences between the groups in understanding treatment goals, drug regimens, lifestyle modifications, psychogenic disorders, and satisfaction evaluations were more pronounced (P<0.01). At six-month follow-up, the difference between the groups in drug therapy compliance was P<0.01, as was success rate by intention-to-treat (77.8% vs. 48.9%) and per-protocol (81.4% vs. 52.4%). Two adverse drug reactions occurred in the experimental group and three in the control group. Pharmacist support improved self-care ability, quality of life, drug therapy compliance, and treatment success rate in coronary heart disease patients.
authors.affiliation: Department of Pharmacy, People's Hospital of Henan Province, Zhengzhou-450 003, China.
authors.forename: S J
authors.initials: SJ
authors.lastname: Zhao
authors.affiliation: Department of Pharmacy, People's Hospital of Henan Province, Zhengzhou-450 003, China.
authors.forename: H W
authors.initials: HW
authors.lastname: Zhao
authors.affiliation: Department of Cardiovascular Medicine, People's Hospital of Henan Province, Zhengzhou-450 003, China.
authors.forename: S
authors.initials: S
authors.lastname: Du
authors.affiliation: Department of Pharmacy, People's Hospital of Henan Province, Zhengzhou-450 003, China.
authors.forename: Y H
authors.initials: YH
authors.lastname: Qin
keywords: Coronary heart disease; clinical pharmacy service; pharmacist; quality of life