title: Biotechnological Aspects and Perspective of Microbial Keratinase Production.
abstract: Keratinases are proteolytic enzymes predominantly active when keratin substrates are available that attack disulfide bridges in the keratin to convert them from complex to simplified forms. Keratinases are essential in preparation of animal nutrients, protein supplements, leather manufacture, textile processing, detergent formulation, feather meal processing for feed and fertilizer, the pharmaceutical and biomedical industries, and waste management. Accordingly, it is necessary to develop a method for continuous production of keratinase from reliable sources that can be easily managed. Microbial keratinase is less expensive than conventionally produced keratinase and can be obtained from fungi, bacteria, and actinomycetes. In this overview, the expansion of information about microbial keratinases and important considerations in keratinase production are discussed.
authors.affiliation: Institute of Nano Electronic Engineering (INEE), Universiti Malaysia Perlis, 01000 Kangar, Perlis, Malaysia ; Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, 13200 Kepala Batas, Penang, Malaysia ; Department of Oral Biology & Biomedical Sciences and OCRCC, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
authors.forename: Subash C B
authors.initials: SC
authors.lastname: Gopinath
authors.affiliation: Department of Biological Engineering, College of Engineering, Inha University, Incheon 402-751, Republic of Korea.
authors.forename: Periasamy
authors.initials: P
authors.lastname: Anbu
authors.affiliation: Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, 13200 Kepala Batas, Penang, Malaysia.
authors.forename: Thangavel
authors.initials: T
authors.lastname: Lakshmipriya
authors.affiliation: Advanced Medical & Dental Institute (AMDI), Universiti Sains Malaysia, 13200 Kepala Batas, Penang, Malaysia.
authors.forename: Thean-Hock
authors.initials: TH
authors.lastname: Tang
authors.affiliation: Department of Oral Biology & Biomedical Sciences and OCRCC, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia.
authors.forename: Yeng
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Institute of Nano Electronic Engineering (INEE), Universiti Malaysia Perlis, 01000 Kangar, Perlis, Malaysia.
authors.forename: Uda
authors.initials: U
authors.lastname: Hashim
authors.affiliation: Institute of Nano Electronic Engineering (INEE), Universiti Malaysia Perlis, 01000 Kangar, Perlis, Malaysia.
authors.forename: A Rahim
authors.initials: AR
authors.lastname: Ruslinda
authors.affiliation: Institute of Nano Electronic Engineering (INEE), Universiti Malaysia Perlis, 01000 Kangar, Perlis, Malaysia.
authors.forename: M K Md
authors.initials: MK
authors.lastname: Arshad
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry*; D001709:Biotechnology / Q000379:methods*; D006801:Humans; D010447:Peptide Hydrolases / Q000737:chemistry*
chemical_list: D001426:Bacterial Proteins; D010447:Peptide Hydrolases; C035855:keratinase