title: Paraneoplastic diarrhea in a patient with lung adenocarcinoma.
abstract: We present a case of newly diagnosed lung adenocarcinoma and a five-month history of diarrhea. The patient was found to have elevated chromogranin A serum levels and the tumor displayed histologic and immunohistochemical features of neuroendocrine differentiation. Upon lobectomy and tumor resection, the chromogranin A levels normalized and the diarrhea resolved completely. This is the first reported case of paraneoplastic diarrhea associated with lung adenocarcinoma.
authors.affiliation: Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9151, USA.
authors.forename: Anh D
authors.initials: AD
authors.lastname: Nguyen
authors.affiliation: Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Valasek
authors.affiliation: Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9151, USA. ezra.burstein@utsouthwestern.edu.
authors.forename: Ezra
authors.initials: E
authors.lastname: Burstein
keywords: Lung cancer; Paraneoplastic; Secretory diarrhea