title: Effect of intraocular lens glistening size on visual quality.
abstract: OBJECTIVE
  To determine whether intraocular glistenings have an impact on light scatter and visual function.
  
  
  METHODS
  John A. Moran Eye Center Laboratories, University of Utah, Salt Lake City, Utah, USA.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Pseudophakic patients with visual acuity no worse than 0.02 logMAR and no ocular pathology were enrolled. All had received a single-piece high-refractive-index acrylic intraocular lens (IOL). All IOLs were photographed, and glistenings were analyzed for size and density. Outcome measures included logMAR corrected distance visual acuity (CDVA), mesopic 10% contrast logMAR CDVA with and without glare, and straylight determination with a straylight meter (C Quant log).
  
  
  RESULTS
  All 79 patients had glistenings within 2 diameter groups: 6 to 25 μm and over 25 μm. Linear regression for the nonstratified group was significant for IOL glistening size versus contrast visual acuity with glare. Linear regression for the 6 to 25 μm group was significant for a measure of severity index (%area) versus the straylight meter measurements, %area/size versus straylight meter measurements, IOL age versus CDVA, IOL age versus contrast visual acuity, and IOL age versus contrast visual acuity with glare. Linear regression for the over 25 μm group was significant for IOL age versus glistening size and %area/size versus contrast visual acuity, and density versus CDVA and contrast visual acuity with glare.
  
  
  CONCLUSIONS
  Glistening %area, at a key size, correlated with random light scatter. The age of the IOL likely affects glistening size and visual parameters.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah, USA.
authors.forename: Bradley S
authors.initials: BS
authors.lastname: Henriksen
authors.affiliation: From the Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah, USA.
authors.forename: Krista
authors.initials: K
authors.lastname: Kinard
authors.affiliation: From the Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah, USA. Electronic address: randallj.olson@hsc.utah.edu.
authors.forename: Randall J
authors.initials: RJ
authors.lastname: Olson
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008027:Light; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D010865:Pilot Projects; D019591:Pseudophakia / Q000503:physiopathology*; D012189:Retrospective Studies; D012542:Scattering, Radiation; D014617:Vacuoles; D014792:Visual Acuity / Q000502:physiology*
chemical_list: D000180:Acrylic Resins