title: Bioinduced Room-Temperature Methanol Reforming.
abstract: Imitating nature's approach in nucleophile-activated formaldehyde dehydrogenation, air-stable ruthenium complexes proved to be exquisite catalysts for the dehydrogenation of formaldehyde hydrate as well as for the transfer hydrogenation to unsaturated organic substrates at loadings as low as 0.5 mol %. Concatenation of the chemical hydrogen-fixation route with an oxidase-mediated activation of methanol gives an artificial methylotrophic in vitro metabolism providing methanol-derived reduction equivalents for synthetic hydrogenation purposes. Moreover, for the first time methanol reforming at room temperature was achieved on the basis of this bioinduced dehydrogenation path delivering hydrogen gas from aqueous methanol.
authors.affiliation: Department Chemie, Universität zu Köln, Greinstrasse 4-6, 50939 Cologne (Germany) http://www.catalysislab.de.
authors.forename: Leo E
authors.initials: LE
authors.lastname: Heim
authors.affiliation: Department Chemie, Universität zu Köln, Greinstrasse 4-6, 50939 Cologne (Germany) http://www.catalysislab.de.
authors.forename: Daniel
authors.initials: D
authors.lastname: Thiel
authors.affiliation: Department Chemie, Universität zu Köln, Greinstrasse 4-6, 50939 Cologne (Germany) http://www.catalysislab.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Gedig
authors.affiliation: Department Chemie, Universität zu Köln, Greinstrasse 4-6, 50939 Cologne (Germany) http://www.catalysislab.de. jan.deska@aalto.fi.|Current address: Department of Chemistry, Aalto University, Kemistintie 1, 00076 Espoo (Finland). jan.deska@aalto.fi.
authors.forename: Jan
authors.initials: J
authors.lastname: Deska
authors.affiliation: Department Chemie, Universität zu Köln, Greinstrasse 4-6, 50939 Cologne (Germany) http://www.catalysislab.de. martin.prechtl@uni-koeln.de.
authors.forename: Martin H G
authors.initials: MH
authors.lastname: Prechtl
mesh_terms: D005557:Formaldehyde / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D006865:Hydrogenation; D000432:Methanol / Q000737:chemistry*; D010088:Oxidoreductases / Q000378:metabolism; D012428:Ruthenium / Q000737:chemistry*; D013696:Temperature
chemical_list: D005557:Formaldehyde; D012428:Ruthenium; D006859:Hydrogen; D010088:Oxidoreductases; D000432:Methanol
keywords: biocatalysis; bioinspired reactions; chemoenzymatic reactions; hydrogen; ruthenium