title: Magnetic field activated drug delivery using thermodegradable azo-functionalised PEG-coated core-shell mesoporous silica nanoparticles.
abstract: Core-shell Fe3O4@SiO2 mesoporous silica nanoparticles coated with a new thermodegradable polymer allowed the release of a model drug through heating caused by a high frequency oscillating magnetic field. The thermodegradable polymer was made of poly(ethylene glycol) (PEG) functionalised with azo bonds that break with an elevation of temperature.
authors.affiliation: Department of Chemistry and Biochemistry, and California NanoSystems Institute, University of California Los Angeles, 607 Charles E. Young Drive East, Los Angeles, California 90095, United States.
authors.forename: P
authors.initials: P
authors.lastname: Saint-Cricq
authors.affiliation: Bioengineering Department, and California NanoSystems Institute University of California Los Angeles, 410 Westwood Plaza, Los Angeles, California 90095-1600, United States.
authors.forename: S
authors.initials: S
authors.lastname: Deshayes
authors.affiliation: Department of Chemistry and Biochemistry, and California NanoSystems Institute, University of California Los Angeles, 607 Charles E. Young Drive East, Los Angeles, California 90095, United States.
authors.forename: J I
authors.initials: JI
authors.lastname: Zink
authors.affiliation: Bioengineering Department, and California NanoSystems Institute University of California Los Angeles, 410 Westwood Plaza, Los Angeles, California 90095-1600, United States.
authors.forename: A M
authors.initials: AM
authors.lastname: Kasko
mesh_terms: D016503:Drug Delivery Systems / Q000379:methods*; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D053758:Nanoparticles; D011092:Polyethylene Glycols / Q000737:chemistry*; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D011092:Polyethylene Glycols; D012822:Silicon Dioxide; C000595209:polyethylene glycol 1000; D052203:Ferrosoferric Oxide