title: Measurements of 2D distributions of absorbed dose in protontherapy with Gafchromic EBT3 films.
abstract: A study of the response of EBT3 films to protons has been carried out with the aim of finding a simple modality to achieve dose images in which the effect of the film sensitivity dependence on radiation LET is amended. Light transmittance images (around 630 nm) were acquired by means of a CCD camera and the difference of optical density was assumed as dosimeter response. The calibration of EBT3 film was performed by means of protons of 173.61 MeV. Some EBT3 films were exposed, in a solid-water phantom, to proton beams of three different energies (89.17 MeV, 110.96 MeV and 130.57 MeV) and the obtained depth-dose profiles were compared with the calculated profiles. From the ratios of calculated and measured Bragg peaks, a trend of the decrease in EBT3 sensitivity with increasing peak depth has been deduced. A method for correcting the data measured with EBT3 films, utilizing the file of irradiation planning data, has been proposed and tested. The results confirm that the method can be advantageously applied for obtaining spatial distribution of the absorbed dose in proton therapy.
authors.affiliation: Department of Physics, Università degli Studi di Milano and INFN, Milano, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Gambarini
authors.affiliation: Department of Physics, Università degli Studi di Milano and INFN, Milano, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Regazzoni
authors.affiliation: Department of Physics, Università degli Studi di Milano and INFN, Milano, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Artuso
authors.affiliation: Department of Physics, Università degli Studi di Milano and INFN, Milano, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Giove
authors.affiliation: Medical Physics Unit, Centro Nazionale di Adroterapia Oncologica (CNAO), Pavia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Mirandola
authors.affiliation: Medical Physics Unit, Centro Nazionale di Adroterapia Oncologica (CNAO), Pavia, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Ciocca
mesh_terms: D065638:Absorption, Radiation; D004307:Dose-Response Relationship, Radiation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005373:Film Dosimetry / Q000295:instrumentation* / Q000379:methods; D061766:Proton Therapy / Q000295:instrumentation*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity
keywords: Dose imaging; Gafchromic EBT3 film; Proton therapy; SOBP