title: A Convenient Synthetic Protocol to 1,2-Bis(dialkylphosphino)ethanes.
abstract: 1,2-Bis(dialkylphosphino)ethanes are readily prepared from the parent phosphine oxides,viaa novel sodium aluminium hydride/sodium hydride reduction protocol of intermediate chlorophosphonium chlorides. This approach is amenable to multi-gram syntheses, utilises readily available and inexpensive reagents, and benefits from a facile non-aqueous work-up in the final reductive step.
authors.affiliation: Department of Chemistry, Imperial College London London SW7 2AZ, U.K. E-mail: a.ashley@imperial.ac.uk.
authors.forename: Laurence R
authors.initials: LR
authors.lastname: Doyle
authors.affiliation: Department of Chemistry, Imperial College London London SW7 2AZ, U.K. E-mail: a.ashley@imperial.ac.uk.
authors.forename: Alex
authors.initials: A
authors.lastname: Heath
authors.affiliation: Department of Chemistry, Imperial College London London SW7 2AZ, U.K. E-mail: a.ashley@imperial.ac.uk.
authors.forename: Choon Heng
authors.initials: CH
authors.lastname: Low
authors.affiliation: Department of Chemistry, Imperial College London London SW7 2AZ, U.K. E-mail: a.ashley@imperial.ac.uk.
authors.forename: Andrew E
authors.initials: AE
authors.lastname: Ashley
keywords: aluminium; hydrides; phosphane ligands; reduction; synthetic methods