title: Renal function overestimation in underweight and/or non-ambulatory patients.
abstract: Creatinine clearance estimation is widely used to evaluate the renal function of the patients in order to initiate or adjust the drugs dosage. However serum creatinine, as a muscle metabolism by-product, may not be a reliable parameter in underweight and/or non-ambulatory patients, such as geriatric, acquired immunodeficiency syndrome patients and bed-confined and cachexic cases. To avoid overestimation of the renal function in those patients, serum cystatin C can be considered as a sensitive and accurate alternative for serum creatinine.
authors.affiliation: UCSI University, Kuala Lumpur, Malaysia. fazlollahk@yahoo.com.
authors.forename: Fazlollah
authors.initials: F
authors.lastname: Keshavarzi
mesh_terms: D016477:Artifacts; D003404:Creatinine / Q000097:blood*; D055316:Cystatin C / Q000097:blood*; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods*; D051346:Mobility Limitation; D015203:Reproducibility of Results; D013851:Thinness / Q000097:blood*
chemical_list: D055316:Cystatin C; D003404:Creatinine
keywords: Bed-confined; Creatinine clearance; Cystatin C; Renal function overestimation; Underweight patients