title: Quality of life after surgery for rectal cancer: a systematic review of comparisons with the general population.
abstract: Rectal cancer treatments may impact negatively on patients' bowel and sexual functions and, in turn, on health-related quality of life. Information on the likely effects of treatment is essential in order to facilitate the care process and the adaptation of patients to their condition. Studies that report on the comparison between rectal cancer patients and the general population are a useful source of this evidence, providing elements to aid in answering questions such as 'is my life going to be the same as before?' In this article, the authors have systematically reviewed articles published in the last 6 years that report on the comparison between rectal patients' and the general population's health-related quality of life. Sixteen out of 645 articles were included. The results are summarized and critically discussed.
authors.affiliation: a 1 Department of Surgical, Oncological and Gastroenterological Sciences, Clinica Chirurgica 1st, University of Padova, c/o Salvatore Pucciarelli, Clinica Chirurgica I, Policlinico Universitario, via Giustiniani, 2, 35128 Padova, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Giandomenico
authors.forename: Teresa
authors.initials: T
authors.lastname: Gavaruzzi
authors.forename: Lorella
authors.initials: L
authors.lastname: Lotto
authors.forename: Paola
authors.initials: P
authors.lastname: Del Bianco
authors.forename: Andrea
authors.initials: A
authors.lastname: Barina
authors.forename: Alessandro
authors.initials: A
authors.lastname: Perin
authors.forename: Salvatore
authors.initials: S
authors.lastname: Pucciarelli
mesh_terms: D006305:Health Status Indicators; D006801:Humans; D020360:Neoadjuvant Therapy; D009364:Neoplasm Recurrence, Local / Q000523:psychology / Q000601:surgery; D011183:Postoperative Complications / Q000523:psychology; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000523:psychology / Q000601:surgery* / Q000628:therapy
keywords: general population; health-related quality of life; rectal cancer; surgery; systematic review