title: The importance of plasma D-2HG measurement in screening for IDH mutations in acute myeloid leukaemia.
authors.affiliation: UT Southwestern Medical School, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: McGehee
authors.affiliation: Department of Pathology and Laboratory Medicine, Children's Medical Center, Dallas, TX, USA.|Departments of Pathology and Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Dinesh
authors.initials: D
authors.lastname: Rakheja
authors.affiliation: Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Dwight
authors.initials: D
authors.lastname: Oliver
authors.affiliation: Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Weina
authors.initials: W
authors.lastname: Chen
authors.affiliation: Department of Pathology and Laboratory Medicine, Children's Medical Center, Dallas, TX, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Boriack
authors.affiliation: Hematology/Oncology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. robert.collins@utsouthwestern.edu.
authors.forename: Robert H
authors.initials: RH
authors.lastname: Collins
mesh_terms: D000368:Aged; D000429:Alcohol Oxidoreductases / Q000378:metabolism*; D004252:DNA Mutational Analysis; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000097:blood / Q000235:genetics*; D015479:Leukemia, Myelomonocytic, Acute / Q000097:blood / Q000235:genetics*; D008297:Male; D009154:Mutation / Q000235:genetics*
chemical_list: D000429:Alcohol Oxidoreductases; D007521:Isocitrate Dehydrogenase; C023858:2-hydroxyglutarate dehydrogenase
keywords: acute myeloid leukaemia; genetic analysis; leukaemia oncogenes; mutation detection; new drugs for leukaemia