title: The effect of selected environmental Fusarium mycotoxins on the ovaries in the female wild boar (Sus scrofa).
abstract: The contamination of agricultural crops with Fusarium mycotoxins poses one of the greatest problems in food production. Wild boars live in specific habitats and are physiologically sensitive to Fusarium mycotoxins, therefore, they are an interesting model for studies investigating the effects of the discussed toxin, in particular under low-dose exposure. The objective of this study was to determine potential effects of Fusarium mycotoxins ingested with naturally contaminated food on reproductive function based on the proliferation and apoptotic indices of ovarian follicles in female wild boars. The experiment was conducted on 40 wild boars inhabiting north-eastern Poland. The effect of seasonal variations in the quantity and quality of ingested food on the concentrations of Fusarium mycotoxins and their metabolites in the blood of wild boars was analyzed. The observed differences in toxin levels were accompanied by changes in proliferation and apoptotic indices. Proliferation processes were most intense in autumn-winter and were least advanced in winter-spring. The intensity of apoptotic processes was inversely correlated with proliferation.
authors.forename: Ł
authors.initials: Ł
authors.lastname: Zielonka
authors.forename: M
authors.initials: M
authors.lastname: Gajęcka
authors.forename: J
authors.initials: J
authors.lastname: Żmudzki
authors.forename: M
authors.initials: M
authors.lastname: Gajęcki
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D005260:Female; D005670:Fusarium / Q000737:chemistry*; D007150:Immunohistochemistry; D009183:Mycotoxins / Q000737:chemistry* / Q000378:metabolism; D010053:Ovary / Q000737:chemistry* / Q000187:drug effects / Q000378:metabolism; D018809:Proliferating Cell Nuclear Antigen / Q000378:metabolism; D012621:Seasons; D034421:Sus scrofa / Q000378:metabolism*
chemical_list: D009183:Mycotoxins; D018809:Proliferating Cell Nuclear Antigen