title: Regioselective synthesis of nitrosoimidazoheterocycles using tert-butyl nitrite.
abstract: A simple and practical method has been developed for the regioselective nitrosylation of imidazopyridines via C(sp(2))-H bond functionalization using tert-butyl nitrite under mild reaction conditions in a short time. A library of 3-nitrosoimidazopyridines with broad functionalities was synthesized in near quantitative yields. The present protocol is also applicable to imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole.
authors.affiliation: Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India. alakananda.hajra@visva-bharati.ac.in.
authors.forename: Kamarul
authors.initials: K
authors.lastname: Monir
authors.forename: Monoranjan
authors.initials: M
authors.lastname: Ghosh
authors.forename: Sourav
authors.initials: S
authors.lastname: Jana
authors.forename: Pallab
authors.initials: P
authors.lastname: Mondal
authors.forename: Adinath
authors.initials: A
authors.lastname: Majee
authors.forename: Alakananda
authors.initials: A
authors.lastname: Hajra
mesh_terms: D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009573:Nitrites / Q000737:chemistry*; D009603:Nitroso Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D007093:Imidazoles; D009573:Nitrites; D009603:Nitroso Compounds; D011725:Pyridines; D013844:Thiazoles; C024225:n-butyl nitrite