title: [Safety of plasma exchange therapy in patients with anti-NMDA receptor encephalitis].
abstract: OBJECTIVE
  To explore the safety of plasma exchange (PE) therapy in patients with anti-NMDA receptor encephalitis.
  
  
  METHODS
  Prospective reviews were conducted for the adverse events and therapeutic efficacies of PE therapy in 9 patients with anti-NMDA receptor encephalitis admitted into neuro-intensive care unit from January 2012 to January 2015.
  
  
  RESULTS
  A total of 54 PE procedures were performed. The NMDA receptor antibody titer of cerebrospinal fluid (CSF) and/or sera in 9 patients (100%) decreased or turned negative. Five patients (55.5%) demonstrated clinical improvement after PE therapy. And clinical complications included frequent involuntary movements, hypotension, coagulation of PE channel, febricity, allergic response and errhysis around peripheral venous access.
  
  
  CONCLUSIONS
  PE is effective, safe and well-tolerated in patients with anti-NMDA receptor encephalitis.
authors.affiliation: Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China; Email: zhangylq@sina.com.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
authors.forename: Daiquan
authors.initials: D
authors.lastname: Gao
authors.affiliation: Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Ye
authors.affiliation: Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
authors.forename: Yingying
authors.initials: Y
authors.lastname: Su
mesh_terms: D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis; D006801:Humans; D010951:Plasma Exchange; D010956:Plasmapheresis; D011446:Prospective Studies; D016194:Receptors, N-Methyl-D-Aspartate
chemical_list: D016194:Receptors, N-Methyl-D-Aspartate