title: Rigiscan Evaluation of Men with Diabetes Mellitus and Erectile Dysfunction and Correlation with Diabetes Duration, Age, BMI, Lipids and HbA1c.
abstract: OBJECTIVE
  This study aimed to investigate differences between patients with type 1 and type 2 diabetes mellitus with erectile dysfunction (ED) evaluated with Rigiscan and if there were a correlation to age, duration of diabetes, BMI, sex hormones, lipids and HbA1c.
  
  
  METHODS
  A retrospective study on patients with type 1 diabetes (n=15), type 2 diabetes (n=17) and a control group (n=31) that underwent Rigiscan examination for ED. Age, BMI, blood pressure, sex hormones, lipids and HbA1c were recorded and analyzed between groups.
  
  
  RESULTS
  Diabetes duration and HbA1C did not correlate with Rigiscan outcome. Rigiscan measures did not differ between patients with type 1 diabetes and control subjects besides from fewer erectile episodes (p<0.01) and lower tumescence activity units in base (p<0.05). By contrast, patients with type 2 diabetes differed significantly with respect to RigiScan parameters both in comparison with the type 1 diabetic patients and the control group. BMI had a strong correlation to number of erectile episodes, duration of erection, duration of erection > 60 % and rigidity activated unit (RAU) in tip and base. Age and HDL-cholesterol had a significant correlation with number of erectile episodes during night (p <0.05).
  
  
  CONCLUSIONS
  Our results indicate that erectile dysfunction in men with diabetes differ between type 1 and type 2 diabetes patients. Neither diabetes duration nor HbA1C correlated to grade of erectile dysfunction among patients with diabetes. Increased BMI might be an explanation to the increased rate of erectile dysfunction seen in patients with type 2 diabetes.
authors.affiliation: Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Huddinge, Sweden.
authors.forename: Daniel Peter
authors.initials: DP
authors.lastname: Andersson
authors.affiliation: Department of Medicine and Centre for Andrology and Sexual Medicine, Karolinska University Hospital and Karolinska Institutet, Huddinge, Sweden.
authors.forename: Urban
authors.initials: U
authors.lastname: Ekström
authors.affiliation: Department of Medicine, Karolinska University Hospital and Karolinska Institutet, Huddinge, Sweden; Department of Medicine and Centre for Andrology and Sexual Medicine, Karolinska University Hospital and Karolinska Institutet, Huddinge, Sweden.
authors.forename: Mikael
authors.initials: M
authors.lastname: Lehtihet
mesh_terms: D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D007172:Erectile Dysfunction / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D002784:Cholesterol; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human