title: Antioxidant and Hypoglycemic Activities of Exopolysaccharide by Submerged Culture of Inocutus Hispidus.
abstract: This work was to investigate the hypoglycemic and antioxidant activities of the exopolysaccharides produced in a stirred-tank bioreactor by Inocutus hispidus. The exopolysaccharides showed significant antioxidant activities, up to 70.7±2.5% inhibition of hydroxyl radicals, 50% inhibition of 2,2-diphenyl-1-picrylhydrazyl radicals, and a Trolox equivalent antioxidant capacity of 3.3 mM. The exopolysaccharide also showed notable hypoglycemic effects in streptozotocin-induced diabetic mice, reducing the plasma glucose, total cholesterol and triacylglycerol concentrations by 18.2±1.5, 20.9±0.8 and 14.4±0.4, respectively. The results demonstrated the potential of this EPS for human health protection against oxidative damage and hyperglycemia.
authors.affiliation: Technical center of China Tobacco Guangxi Industrial Co. Ltd., Nanning-530 001, China.
authors.forename: S H
authors.initials: SH
authors.lastname: Liu
authors.affiliation: College of Food and Biological Engineering, Zhengzhou University of Light Industry, Henan-450 002, China.
authors.forename: S W
authors.initials: SW
authors.lastname: Sun
authors.affiliation: Technical center of China Tobacco Guangxi Industrial Co. Ltd., Nanning-530 001, China.
authors.forename: Z F
authors.initials: ZF
authors.lastname: Tian
authors.affiliation: Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
authors.forename: J Y
authors.initials: JY
authors.lastname: Wu
authors.affiliation: Technical center of China Tobacco Guangxi Industrial Co. Ltd., Nanning-530 001, China.
authors.forename: X L
authors.initials: XL
authors.lastname: Li
authors.affiliation: College of Food and Biological Engineering, Zhengzhou University of Light Industry, Henan-450 002, China.
authors.forename: C P
authors.initials: CP
authors.lastname: Xu
keywords: Exopolysaccharides; Inocutus hispidus; antioxidant; fermentation; hypoglycemic effect