title: Ceftaroline fosamil: A super-cephalosporin?
abstract: Ceftaroline is a broad-spectrum cephalosporin used to treat infections caused by a variety of microorganisms, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae. However, it is not active against Pseudomonas aeruginosa, Bacteroides fragilis, and carbapenem-resistant Enterobacteriaceae. Its approved indications include community-acquired bacterial pneumonia and bacterial infections of skin and skin structures. It has also been used off-label to treat osteomyelitis, endocarditis, and meningitis caused by ceftaroline-susceptible organisms.
authors.affiliation: Clinical Pharmacist Specialist, Adult Antimicrobial Stewardship Department of Pharmacy, University Hospitals Case Medical Center, Cleveland, OH, USA.
authors.forename: Riane J
authors.initials: RJ
authors.lastname: Ghamrawi
authors.affiliation: Infectious Diseases Clinical Specialist, Department of Pharmacy, Cleveland Clinic, Cleveland, OH, USA. E-mail: neunere@ccf.org.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Neuner
authors.affiliation: Department of Infectious Disease, Cleveland Clinic, Cleveland, OH, USA.|Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Rehm
mesh_terms: D000328:Adult; D002511:Cephalosporins / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D000097583:Ceftaroline
chemical_list: D002511:Cephalosporins; D000097583:Ceftaroline