title: A contamination-insensitive probe for imaging specific biomolecules by secondary ion mass spectrometry.
abstract: Imaging techniques should differentiate between specific signals, from the biomolecules of interest, and non-specific signals, from the background. We present a probe containing (15)N and (14)N isotopes in approximately equal proportion, for secondary ion mass spectrometry imaging. This probe designed for a precise biomolecule analysis is insensitive to background signals.
authors.affiliation: Institute of Organic and Biomolecular Chemistry, University of Göttingen, Tammannstr. 2, D-37077 Göttingen, Germany. udieder@gwdg.de.
authors.forename: Selda
authors.initials: S
authors.lastname: Kabatas
authors.forename: Ingrid C
authors.initials: IC
authors.lastname: Vreja
authors.forename: Sinem K
authors.initials: SK
authors.lastname: Saka
authors.forename: Carmen
authors.initials: C
authors.lastname: Höschen
authors.forename: Katharina
authors.initials: K
authors.lastname: Kröhnert
authors.forename: Felipe
authors.initials: F
authors.lastname: Opazo
authors.forename: Silvio O
authors.initials: SO
authors.lastname: Rizzoli
authors.forename: Ulf
authors.initials: U
authors.lastname: Diederichsen
mesh_terms: D003952:Diagnostic Imaging / Q000295:instrumentation*; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D059629:Signal-To-Noise Ratio; D018629:Spectrometry, Mass, Secondary Ion
chemical_list: D005456:Fluorescent Dyes