title: Gastric Emptying in the Elderly.
abstract: Aging is characterized by a diminished homeostatic regulation of physiologic functions, including slowing of gastric emptying. Gastric and small intestinal motor and humoral mechanisms in humans are complex and highly variable: ingested food is stored, mixed with digestive enzymes, ground into small particles, and delivered as a liquefied form into the duodenum at a rate allowing efficient digestion and absorption. In healthy aging, motor function is well preserved whereas deficits in sensory function are more apparent. The effects of aging on gastric emptying are relevant to the absorption of oral medications and the regulation of appetite, postprandial glycemia, and blood pressure.
authors.affiliation: Discipline of Medicine, National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence in Translating Nutritional Science to Good Health, Royal Adelaide Hospital, The University of Adelaide, Frome Road, Adelaide, South Australia 5000, Australia. Electronic address: stijn.soenen@adelaide.edu.au.
authors.forename: Stijn
authors.initials: S
authors.lastname: Soenen
authors.affiliation: Discipline of Medicine, National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence in Translating Nutritional Science to Good Health, Royal Adelaide Hospital, The University of Adelaide, Frome Road, Adelaide, South Australia 5000, Australia.
authors.forename: Chris K
authors.initials: CK
authors.lastname: Rayner
authors.affiliation: Discipline of Medicine, National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence in Translating Nutritional Science to Good Health, Royal Adelaide Hospital, The University of Adelaide, Frome Road, Adelaide, South Australia 5000, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Horowitz
authors.affiliation: Discipline of Medicine, National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence in Translating Nutritional Science to Good Health, Royal Adelaide Hospital, The University of Adelaide, Frome Road, Adelaide, South Australia 5000, Australia.
authors.forename: Karen L
authors.initials: KL
authors.lastname: Jones
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D065570:Gastric Absorption / Q000502:physiology; D005746:Gastric Emptying / Q000502:physiology*; D005768:Gastrointestinal Hormones / Q000378:metabolism; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D016065:Myoelectric Complex, Migrating / Q000502:physiology*
chemical_list: D005768:Gastrointestinal Hormones
keywords: Blood pressure; Breath tests; Gastric emptying; Glycemia; Migrating motor complex; Neural and humoral feedback; Scintigraphy; Ultrasonography