title: First confirmed case of spondylodiscitis with epidural abscess caused by Parvimonas micra.
abstract: Parvimonas micra was renamed species as within Gram-positive anaerobic cocci and rarely causes severe infections in healthy people. We report the first confirmed case of spondylodiscitis with epidural abscess caused by P. micra in a healthy women. The patient has a pain in low back and anterior left thigh. Magnetic resonance imaging and computed tomography detected the affected lesion at the L2 and L3 vertebral bodies. All isolates from the surgical and needle biopsy specimens were identified as P. micra by 16S rRNA and MALDI-TOF. In this case, P. micra showed high sensitivity to antimicrobial therapy. She was successfully treated with debridement and sulbactam/ampicillin, followed by oral metronidazole for a total of 10 weeks. The causative microorganisms of spondylodiscitis are not often identified, especially anaerobic bacteria tend to be underestimated. On the other hand, antimicrobial therapy for spondylodiscitis is usually prolonged. Accordingly, we emphasize the importance of performing accurate identification including anaerobic bacteria.
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan. Electronic address: ain@med.tohoku.ac.jp.
authors.forename: Shiro
authors.initials: S
authors.lastname: Endo
authors.affiliation: Izumi Orthopaedic Hospital, 6-1, Maruyama, Kamiyagari, Izumi-ku, Sendai, Miyagi 981-3121, Japan.
authors.forename: Tadanobu
authors.initials: T
authors.lastname: Nemoto
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Hisakazu
authors.initials: H
authors.lastname: Yano
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Risako
authors.initials: R
authors.lastname: Kakuta
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Kanamori
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Inomata
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Noriomi
authors.initials: N
authors.lastname: Ishibashi
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Aoyagi
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Masumitsu
authors.initials: M
authors.lastname: Hatta
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Gu
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Miho
authors.initials: M
authors.lastname: Kitagawa
authors.affiliation: Department of Infection Control and Laboratory Diagnostics, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Kaku
mesh_terms: D015299:Discitis / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology; D020802:Epidural Abscess / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology; D005260:Female; D000068536:Bacillota; D006801:Humans; D008875:Middle Aged
keywords: 16S ribosomal RNA; Gram-positive anaerobic cocci; Parvimonas micra; Spondylodiscitis with epidural abscess