title: The Role of Nutrition and Physical Activity in Cholesterol and Aging.
abstract: Cholesterol is a precursor of several substances with important biologic activities; however, it is common to associate this molecule only with bad outcomes. This article reviews the cholesterol metabolism, its functions in the human body, its pathogenicity, and its elimination. The modifications in biochemical paths of cholesterol in aging are highlighted. Finally, the role of diet, physical activity, and exercise in cholesterol management is discussed.
authors.affiliation: Research Group of Nutrition, Physical Activity and Aging Processes, Department of Gerontology, University of São Paulo, Avenue Arlindo Bettio 1000, Ermelino Matarazzo, São Paulo, CEP 03828-000, Brazil. Electronic address: smlribeiro@usp.br.
authors.forename: Sandra Maria Lima
authors.initials: SM
authors.lastname: Ribeiro
authors.affiliation: Research Group of Nutrition, Physical Activity and Aging Processes, University of São Paulo, Avenue Arlindo Bettio 1000, Ermelino Matarazzo, São Paulo, CEP 03828-000, Brazil.
authors.forename: Silmara Dos Santos
authors.initials: Sdos S
authors.lastname: Luz
authors.affiliation: Nutrition Department, São Judas Tadeu University, Rua Taquari, 546-Mooca, São Paulo, CEP 03166-000, Brazil.
authors.forename: Rita de Cássia
authors.initials: Rde C
authors.lastname: Aquino
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology / Q000523:psychology; D000544:Alzheimer Disease / Q000097:blood / Q000209:etiology / Q000517:prevention & control; D050197:Atherosclerosis / Q000097:blood / Q000209:etiology / Q000517:prevention & control; D002784:Cholesterol / Q000378:metabolism*; D005247:Feeding Behavior / Q000502:physiology / Q000523:psychology; D015438:Health Behavior; D006801:Humans; D008074:Lipoproteins / Q000378:metabolism*; D009043:Motor Activity / Q000502:physiology*
chemical_list: D008074:Lipoproteins; D002784:Cholesterol
keywords: Aging; Alzheimer disease; Atherogenesis; Cholesterol; Diet; Lipoproteins; Physical activity; Physical exercise