title: Stabilization in early adult-onset myopia with corneal refractive therapy.
abstract: OBJECTIVE
  To describe the stabilization of early adult-onset myopia in three university students after initiating orthokeratology treatment with corneal refractive therapy contact lenses.
  
  
  METHODS
  Three Caucasian early adult-onset progressing myopic subjects (1 male, 2 females) were fitted with corneal refractive therapy lenses to correct myopia between -1.50 and -2.50 D of sphere using Paragon CRT (Paragon Vision Sciences, Mesa, AZ) lenses for overnight orthokeratology. The pre-treatment refractive history from 2005 as well as refraction and axial length after treatment onset are reported over a period of 3 years between December 2009 and January 2013 with an additional year of follow-up after treatment discontinuation (January-December 2013). The peripheral refractive patterns and topographic changes are also reported individually.
  
  
  RESULTS
  Treatment was successful in all three subjects achieving uncorrected visual acuity of 20/20 or better monocularly. During a period of 3 years of follow-up the subjects did not experience progression in their refractive error, nor in their axial length (measured during the last 2 years of treatment and 1 year after discontinuation). Furthermore, the subjects recovered to their baseline refraction and did not progressed further over the following year after lens wear discontinuation.
  
  
  CONCLUSIONS
  We cannot attribute a causative effect to the orthokeratology treatment alone as underlying mechanism for myopia stabilization in this 3 patients. However, the present report points to the possibility of stabilization of early adult-onset myopia progression in young adults using corneal refractive therapy treatment.
authors.affiliation: Clinical and Experimental Optometry Research Lab. Center of Physics, University of Minho, Braga, Portugal. Electronic address: jgmeijome@fisica.uminho.pt.
authors.forename: José M
authors.initials: JM
authors.lastname: González-Méijome
authors.affiliation: Clinical and Experimental Optometry Research Lab. Center of Physics, University of Minho, Braga, Portugal.
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Carracedo
authors.affiliation: Clinical and Experimental Optometry Research Lab. Center of Physics, University of Minho, Braga, Portugal.
authors.forename: Daniela
authors.initials: D
authors.lastname: Lopes-Ferreira
authors.affiliation: Clinical and Experimental Optometry Research Lab. Center of Physics, University of Minho, Braga, Portugal.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Faria-Ribeiro
authors.affiliation: Clinical and Experimental Optometry Research Lab. Center of Physics, University of Minho, Braga, Portugal.
authors.forename: Sofia C
authors.initials: SC
authors.lastname: Peixoto-de-Matos
authors.affiliation: Clinical and Experimental Optometry Research Lab. Center of Physics, University of Minho, Braga, Portugal.
authors.forename: António
authors.initials: A
authors.lastname: Queirós
mesh_terms: D000293:Adolescent; D000328:Adult; D003261:Contact Lenses; D003315:Cornea / Q000473:pathology*; D019781:Corneal Topography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009216:Myopia / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D054158:Orthokeratologic Procedures / Q000379:methods*; D012029:Refraction, Ocular / Q000502:physiology*; D012189:Retrospective Studies; D055815:Young Adult
keywords: Corneal refractive therapy; Early adult-onset myopia; Myopia control; Orthokeratology