title: The role of vitamin D in atopic dermatitis.
abstract: Vitamin D has been suggested to have an important impact on a much wider aspects on human health than calcium homeostasis and mineral metabolism, specifically in the field of human immunology. It has been reported that vitamin D influences the regulation of both innate and adaptive immune systems, which makes the association between vitamin D and allergic diseases a field of interest. Although many studies have sought to determine whether vitamin D has an influence on progression of allergic disease, the impact of vitamin D on atopic dermatitis development and severity remains unclear. In this review, we summarize recent studies relating vitamin D to atopic dermatitis and discuss its possible role in the pathogenesis of allergic skin diseases, emphasizing the need for well-designed, prospective trials on vitamin D supplementation in the context of prevention and treatment for allergic conditions.
authors.affiliation: From the 1st Department and Clinic of Paediatrics, Allergology and Cardiology, Wroclaw Medical University, Wrocław, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Dębińska
authors.forename: Hanna
authors.initials: H
authors.lastname: Sikorska-Szaflik
authors.forename: Magdalena
authors.initials: M
authors.lastname: Urbanik
authors.forename: Andrzej
authors.initials: A
authors.lastname: Boznański
mesh_terms: D003876:Dermatitis, Atopic / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology*; D019587:Dietary Supplements; D006801:Humans; D012720:Severity of Illness Index; D012867:Skin / Q000276:immunology*; D014807:Vitamin D / Q000276:immunology* / Q000627:therapeutic use; D014808:Vitamin D Deficiency / Q000453:epidemiology; D014815:Vitamins / Q000627:therapeutic use
chemical_list: D014815:Vitamins; D014807:Vitamin D