title: Consensus statement for brachytherapy for the treatment of medically inoperable endometrial cancer.
abstract: OBJECTIVE
  The purpose of this consensus statement from the American Brachytherapy Society (ABS) is to summarize recent advances and to generate general guidelines for the management of medically inoperable endometrial cancer patients with radiation therapy.
  
  
  METHODS
  Recent advances in the literature were summarized and reviewed by a panel of experts. Panel members participated in a series of conference calls and were surveyed to determine their current practices and patterns. This document was reviewed and approved by the full panel, the ABS Board of Directors and the ACR Commission on Radiation Oncology.
  
  
  RESULTS
  A transition from two-dimensional (2D) to three-dimensional (3D) treatment planning for the definitive treatment of medically inoperable endometrial cancer is described. Magnetic resonance (MR) imaging can be used to define the gross tumor volume (GTV), clinical target volume (CTV), and the organs at risk (OARs). Brachytherapy alone can be used for medically inoperable endometrial cancer patients with clinical Stage I cancer with no lymph node involvement and no evidence of deep invasion of the myometrium on MR imaging. In the absence of MR imaging, a combined approach using external beam and brachytherapy may be considered.
  
  
  CONCLUSIONS
  Recent advances support the use of MR imaging and 3D planning for brachytherapy treatment for medically inoperable endometrial cancer.
authors.affiliation: Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO. Electronic address: jschwarz@radonc.wustl.edu.
authors.forename: Julie K
authors.initials: JK
authors.lastname: Schwarz
authors.affiliation: Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
authors.forename: Sushil
authors.initials: S
authors.lastname: Beriwal
authors.affiliation: Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Esthappan
authors.affiliation: Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI.
authors.forename: Beth
authors.initials: B
authors.lastname: Erickson
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Boston, MA.
authors.forename: Colleen
authors.initials: C
authors.lastname: Feltmate
authors.affiliation: Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
authors.forename: Anthony
authors.initials: A
authors.lastname: Fyles
authors.affiliation: Department of Radiation Oncology, University of Utah School of Medicine, Salt Lake City, UT.
authors.forename: David
authors.initials: D
authors.lastname: Gaffney
authors.affiliation: Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC.
authors.forename: Ellen
authors.initials: E
authors.lastname: Jones
authors.affiliation: Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.
authors.forename: Ann
authors.initials: A
authors.lastname: Klopp
authors.affiliation: Department of Radiation Oncology, Loyola University, Chicago, IL.
authors.forename: William
authors.initials: W
authors.lastname: Small
authors.affiliation: Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI.
authors.forename: Bruce
authors.initials: B
authors.lastname: Thomadsen
authors.affiliation: Department of Radiation Medicine and Applied Sciences, University of California San Diego Moores Cancer Center, San Diego, CA.
authors.forename: Catheryn
authors.initials: C
authors.lastname: Yashar
authors.affiliation: Department of Radiation Oncology, Harvard Medical School, Boston, MA.
authors.forename: Akila
authors.initials: A
authors.lastname: Viswanathan
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects / Q000379:methods*; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009367:Neoplasm Staging; D058958:Organs at Risk; D011859:Radiography; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted
keywords: Brachytherapy; Endometrial carcinoma; Magnetic resonance imaging