title: Direct Interconversion of BINOL and H8-BINOL-Based Chiral Brønsted Acids Using Single-Step Red/Ox Manipulations.
abstract: A direct single-step hydrogenation of BINOL-based chiral phosphoric acids, N-triflyl phosphoramides, and disulfonimides to the corresponding H8-BINOL Brønsted acids in excellent yields and chemoselectivities is described. In addition, the conditions for the single-step oxidation of H8-BINOL-based Brønsted acids into the corresponding BINOL-based acids have been identified and employed to accomplish these interconversions in 41-81% yield.
authors.affiliation: Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.
authors.forename: Jia-Hui
authors.initials: JH
authors.lastname: Tay
authors.affiliation: Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.
authors.forename: Alonso J
authors.initials: AJ
authors.lastname: Arguelles
authors.affiliation: Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.
authors.forename: Pavel
authors.initials: P
authors.lastname: Nagorny