title: [Anophthalmia and microphthalmia requires multidisciplinary care. Many of the children also have other medical problems].
abstract: Anophthalmia/microphthalmia (A/M) are rare congenital eye malformations. Early intervention with ocular prosthesis can stimulate orbital growth and prevent facial asymmetry. We reviewed medical records from 18 individuals with A/M (0.8-31 years) treated with ocular prosthesis at Sahlgrenska University Hospital between 2000 and 2012. A majority had other ocular findings. Seven had subnormal visual acuity in the fellow eye, one third were in contact with vision support services and half of the group wore glasses. Eleven individuals had extra-ocular findings such as cardiac defect, hearing impairment and neuropsychiatric disorders, possibly indicating syndromic conditions. We suggest that investigation of A/M children should include ultrasound of the eye, optionally visual evoked potential and magnetic resonance imaging of the CNS. The ophthalmologist should initiate treatment with prosthesis, pediatric assessment, hearing tests and genetic counseling, but should also monitor visual development of the fellow eye.
authors.affiliation: Ögonkliniken, Södra Älvsborgs Sjukhus - Borås, Sweden - Borås, Sweden.
authors.forename: Ylva
authors.initials: Y
authors.lastname: Jugård
authors.affiliation: Titanenheten, Öron- näs- och halskliniken, Sahlgrenska Universitetssjukhuset - Göteborg, Sweden Titanenheten, Öron- näs- och halskliniken, Sahlgrenska Universitetssjukhuset - Göteborg, Sweden.
authors.forename: Marie
authors.initials: M
authors.lastname: Odersjö
authors.affiliation: Klinisk Genetik, Sahlgrenska Universitetssjukhuset - Göteborg, Sweden Klinisk Genetik, Sahlgrenska Universitetssjukhuset - Göteborg, Sweden.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Topa
authors.affiliation: Ögonverksamheten, Sahlgrenska Universitetssjukhuset - Mölndal, Sweden Ögonverksamheten, Sahlgrenska Universitetssjukhuset - Mölndal, Sweden.
authors.forename: Gun
authors.initials: G
authors.lastname: Lindgren
authors.affiliation: Ögonmottagningen för barn, Drottning Silvias barn- och ungdomssjukhus Sahlgrenska Universitetssjukhuset - Göteborg, Sweden Ögonmottagningen för barn, Drottning Silvias barn- och ungdomssjukhus, Sahlgrenska universitetssjukhuse - Göteborg, Sweden.
authors.forename: Marita
authors.initials: M
authors.lastname: Andersson Grönlund
mesh_terms: D000293:Adolescent; D000328:Adult; D000853:Anophthalmos / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005137:Eye, Artificial; D005260:Female; D006311:Hearing Disorders / Q000150:complications; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007223:Infant; D008297:Male; D008850:Microphthalmos / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D020273:Orbital Implants; D010348:Patient Care Team; D011596:Psychomotor Disorders / Q000150:complications; D014786:Vision Disorders / Q000150:complications