title: Change in Tear Film Lipid Layer Thickness, Corneal Thickness, Volume and Topography after Superficial Cauterization for Conjunctivochalasis.
abstract: We evaluated the change in tear film lipid layer thickness, corneal thickness, volume and topography after superficial cauterization of symptomatic conjunctivochalasis. Bilateral superficial conjunctival cauterization was performed in 36 eyes of 18 patients with symptomatic conjunctivochalasis. The mean age of patients (12 males, 6 females) was 68.6 ± 10.9 years (range: 44-83 years). Preoperatively, 28 eyes (77.8%) had grade 1 conjunctivochalasis, and 8 eyes (22.2%) had grade 2 conjunctivochalasis. At 1 month postoperatively, the severity of conjunctivochalasis decreased significantly (p < 0.001) and 29 eyes (80.6%) had grade 0 conjunctivochalasis whereas 7 eyes (19.4%) had grade 1 conjunctivochalasis. The mean Ocular Surface Disease Index score decreased from 31.5 ± 15.2 preoperatively to 21.5 ± 14.2 at the end of 1 month postoperatively (p = 0.001). There was a statistically significant increase in mean tear film lipid layer thickness 1 month after the surgery (49.6 ± 16.1 nm vs 62.6 ± 21.6 nm; p < 0.001). The central corneal thickness, thinnest corneal thickness and corneal volume decreased significantly postoperatively (p < 0.001). Our study showed that superficial conjunctival cauterization is an effective technique for management of conjunctivochalasis in the short term. An increase in tear film lipid layer thickness along with a decrease in corneal thickness and volume were observed after surgical correction of conjunctivochalasis.
authors.affiliation: 1] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong [2] Hong Kong Eye Hospital, Mongkok, Kowloon, Hong Kong.
authors.forename: Tommy C Y
authors.initials: TC
authors.lastname: Chan
authors.affiliation: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong.
authors.forename: Cong
authors.initials: C
authors.lastname: Ye
authors.affiliation: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong.
authors.forename: Paul K F
authors.initials: PK
authors.lastname: Ng
authors.affiliation: 1] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong [2] Hong Kong Eye Hospital, Mongkok, Kowloon, Hong Kong.
authors.forename: Emmy Y M
authors.initials: EY
authors.lastname: Li
authors.affiliation: 1] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong [2] Hong Kong Eye Hospital, Mongkok, Kowloon, Hong Kong.
authors.forename: Hunter K L
authors.initials: HK
authors.lastname: Yuen
authors.affiliation: 1] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong [2] Hong Kong Eye Hospital, Mongkok, Kowloon, Hong Kong [3] Centre for Eye Research Australia, University of Melbourne, Victoria, Australia.
authors.forename: Vishal
authors.initials: V
authors.lastname: Jhanji
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003229:Conjunctival Diseases / Q000175:diagnosis* / Q000473:pathology; D003315:Cornea / Q000473:pathology*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D007368:Interferometry; D008297:Male; D008875:Middle Aged; D013666:Tears