title: Non-invasive, investigative methods in skin aging.
abstract: A precise and noninvasive quantification of aging is of outmost importance for in vivo assessment of the skin aging "stage", and thus acts to minimize it. Several bioengineering methods have been proposed to objectively, precisely, and non-invasively measure skin aging, and to detect early skin damage, that is sub-clinically observable. In this review we have described the most relevant methods that have emerged from recently introduced technologies, aiming at quantitatively assessing the effects of aging on the skin.
authors.affiliation: Skin Cancer Unit, Arcispedale Santa Maria Nuova‑IRCCS, Reggio Emilia, Italy - longo.caterina@gmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Longo
authors.forename: S
authors.initials: S
authors.lastname: Ciardo
authors.forename: G
authors.initials: G
authors.lastname: Pellacani
mesh_terms: D000886:Anthropometry / Q000379:methods; D003124:Colorimetry / Q000295:instrumentation / Q000379:methods; D003880:Dermatology / Q000379:methods*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D017078:Laser-Doppler Flowmetry; D018613:Microscopy, Confocal / Q000379:methods; D012629:Sebum / Q000737:chemistry; D012867:Skin / Q000098:blood supply / Q000737:chemistry / Q000000981:diagnostic imaging / Q000648:ultrastructure; D015595:Skin Aging; D012880:Skin Pigmentation; D013499:Surface Properties; D041623:Tomography, Optical Coherence; D014463:Ultrasonography