title: Pericarditis as the Presenting Feature of Graves Disease in a Pediatric Patient.
abstract: Pericarditis is a rare presentation of thyrotoxicosis associated with Graves disease. This association has not been previously described in the pediatric literature. We report a 17-year-old male patient who presented with chest pain, dyspnea, and tachycardia. He was found to have diffuse ST-segment elevation consistent with pericarditis. At presentation, he was noted to have bilateral proptosis. Abnormal thyroid function studies and an elevated thyroid-stimulating hormone receptor antibody level confirmed the diagnosis of Graves thyrotoxicosis. The patient was treated with anti-inflammatory and antithyroid agents and improved in time. We discuss previously reported cases of Graves disease-associated pericarditis in adults, potential etiologies, and management strategies.
authors.affiliation: From the *Department of Pediatrics and †Division of Pediatric Endocrinology, Department of Pediatrics, The Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA.
authors.forename: Danielle
authors.initials: D
authors.lastname: Cullen
authors.forename: Neil
authors.initials: N
authors.lastname: Munjal
authors.forename: Hannah
authors.initials: H
authors.lastname: Chalal
authors.forename: Sriram
authors.initials: S
authors.lastname: Ramgopal
authors.forename: Emir
authors.initials: E
authors.lastname: Tas
authors.forename: Selma
authors.initials: S
authors.lastname: Witchel
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D013956:Antithyroid Agents / Q000627:therapeutic use*; D005094:Exophthalmos / Q000188:drug therapy / Q000209:etiology; D006111:Graves Disease / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D010493:Pericarditis / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D013956:Antithyroid Agents