title: Single-port versus conventional multiport access prophylactic laparoscopic bilateral salpingo-oophorectomy in high-risk patients for ovarian cancer: a comparison of surgical outcomes.
abstract: Bilateral salpingo-oophorectomy (BSO) in carriers of BRCA1 and BRCA2 mutations is widely recommended as part of a risk-reduction strategy for ovarian or breast cancer due to an underlying genetic predisposition. BSO is also performed as a therapeutic intervention for patients with hormone-positive premenopausal breast cancer. BSO may be performed via a minimally invasive approach with the use of three to four 5 mm and/or 12 mm ports inserted through a skin incision. To further reduce the morbidity associated with the placement of multiple port sites and to improve cosmetic outcomes, single-port laparoscopy has been developed with a single access point from the umbilicus. The purpose of this study was to evaluate the surgical outcomes associated with reducing the risks of salpingo-oophorectomy performed in a single port, while comparing multiport laparoscopy in women with a high risk for ovarian cancer. Single-port laparoscopy-BSO is feasible and safe, with favorable surgical and cosmetic outcomes when compared to conventional laparoscopy.
authors.affiliation: Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Angioni
authors.affiliation: Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Pontis
authors.affiliation: Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Sedda
authors.affiliation: Obstetrics and Gynecology, Iaso Thessalia Hospital, Larissa, Greece.
authors.forename: Theodoros
authors.initials: T
authors.lastname: Zampetoglou
authors.affiliation: Department of Obstetrics and Gynecology, University of Pisa, Pisa, Italy.
authors.forename: Vito
authors.initials: V
authors.lastname: Cela
authors.affiliation: Ospedale S Chiara, Trento, Italy.
authors.forename: Liliana
authors.initials: L
authors.lastname: Mereu
authors.affiliation: Department of Obstetrics and Gynecology, University of Padua, Padua, Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Litta
keywords: BRCA carriers; prophylactic salpingectomy; single-port access laparoscopy