title: Reconstruction With Pedicled Anterolateral Thigh Flap After Wide Local Excision of Penoscrotal Extramammary Paget's Disease: A Case Report and Comprehensive Literature Review.
abstract: OBJECTIVE
  The clinical characteristics, management, and prognostic indicators of penoscrotal extramammary Paget's disease are not clearly defined. Surgical excision is often an effective treatment modality but results in a large wound after resection of all involved tissues.
  
  
  METHODS
  Reconstruction of large penoscrotal soft-tissue defects after wide local excision remains a challenge to the reconstructive surgeon. The use of the anterolateral thigh flap for penoscrotal reconstruction after resection of extramammary Paget's disease is infrequent as a reconstruction tool throughout the literature.
  
  
  RESULTS
  We discuss a case where the anterolateral thigh flap was effectively used for reconstruction of a large penoscrotal defect after wide local excision of penoscrotal extramammary Paget's disease and present a comprehensive literature review of extramammary Paget's disease key features, diagnosis, prognosis, and treatment.
  
  
  CONCLUSIONS
  The anterolateral thigh flap is a useful tool for penoscrotal defect reconstruction.
authors.affiliation: Division of Plastic Surgery, Stanford University Medical Center, Palo Alto, Calif.
authors.forename: Cedric L
authors.initials: CL
authors.lastname: Hunter
authors.affiliation: Department of Urology, Stanford University Medical Center, Palo Alto, Calif.
authors.forename: Eila C
authors.initials: EC
authors.lastname: Skinner
authors.affiliation: Division of Plastic Surgery, Stanford University Medical Center, Palo Alto, Calif.
authors.forename: Gordon K
authors.initials: GK
authors.lastname: Lee
keywords: anterolateral thigh flap; extramammary Paget’s disease; penoscrotal reconstruction; wide local excision