title: Telomeres and essential hypertension.
abstract: OBJECTIVE
  This review aims to clarify the relationship between telomeres and essential hypertension.
  
  
  METHODS
  A PubMed search and a critical review were performed relating to studies about the clinical and biological relevance of telomeres in essential hypertension.
  
  
  RESULTS
  Telomeres and telomerase activity play an important role in the occurrence and development of hypertension in both animal and human studies.
  
  
  CONCLUSIONS
  A more complete understanding of the molecular mechanisms underlying the development of hypertension could reduce the incidence of hypertension-related diseases.
authors.affiliation: Department of Geriatrics, Xuan Wu Hospital, Capital Medical University, Beijing 100053, China. Electronic address: marina0583@163.com.
authors.forename: Lina
authors.initials: L
authors.lastname: Ma
authors.affiliation: Department of Geriatrics, Xuan Wu Hospital, Capital Medical University, Beijing 100053, China. Electronic address: liyunxw@163.com.
authors.forename: Yun
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Geriatrics, Xuan Wu Hospital, Capital Medical University, Beijing 100053, China. Electronic address: wang_jie_yu@sina.com.
authors.forename: Jieyu
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D000075222:Essential Hypertension; D006801:Humans; D006973:Hypertension / Q000378:metabolism*; D019098:Telomerase / Q000378:metabolism; D016615:Telomere / Q000378:metabolism*
chemical_list: D019098:Telomerase
keywords: Hypertension; Telomerase; Telomere length