title: Ecological and Lineage-Specific Factors Drive the Molecular Evolution of Rhodopsin in Cichlid Fishes.
abstract: The visual system in the colorful cichlid fishes from the African great lakes is believed to be important for their adaptive radiations. However, few studies have attempted to compare the visual system of radiating cichlid lineages with that of cichlids that have not undergone recent radiations. One such study published in this journal (Schott RK, Refvik SP, Hauser FE, López-Fernández H, Chang BSW. 2014. Divergent positive selection in rhodopsin from lake and riverine cichlid fishes. Mol Biol Evol. 31:1149-1165) found divergent selection on rhodopsin between African lacustrine and riverine cichlid species and riverine Neotropical cichlids, concluding that ecology drives the molecular evolution of this opsin. Here, we expand this analysis by incorporating rhodopsin sequences from Neotropical lacustrine cichlids and show that both ecology and phylogeny are important drivers of the molecular evolution of rhodopsin in cichlids. We found little overlap of sites under selection between African and Neotropical lineages and a faster rate of molecular evolution in African compared with Neotropical cichlids. These results support the notion that genetic or population genetic features particular to African cichlids contributed to their radiations.
authors.affiliation: Zoology and Evolutionary Biology, Department of Biology, University of Konstanz, Konstanz, Germany Zukunftskolleg, University of Konstanz, Konstanz, Germany.
authors.forename: Julián
authors.initials: J
authors.lastname: Torres-Dowdall
authors.affiliation: Zoology and Evolutionary Biology, Department of Biology, University of Konstanz, Konstanz, Germany.
authors.forename: Frederico
authors.initials: F
authors.lastname: Henning
authors.affiliation: Zoology and Evolutionary Biology, Department of Biology, University of Konstanz, Konstanz, Germany Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.
authors.forename: Kathryn R
authors.initials: KR
authors.lastname: Elmer
authors.affiliation: Zoology and Evolutionary Biology, Department of Biology, University of Konstanz, Konstanz, Germany axel.meyer@uni-konstanz.de.
authors.forename: Axel
authors.initials: A
authors.lastname: Meyer
mesh_terms: D000818:Animals; D023681:Cichlids / Q000235:genetics* / Q000378:metabolism; D004463:Ecology; D019143:Evolution, Molecular; D014644:Genetic Variation; D005828:Genetics, Population; D060106:Lakes; D010802:Phylogeny; D012243:Rhodopsin / Q000235:genetics* / Q000378:metabolism
chemical_list: D012243:Rhodopsin
keywords: Neotropical cichlids; codon substitution models; dim-light vision; vision; visual pigments