title: Successful treatment with topical imiquimod of anal Buschke-Löwenstein tumor in a child.
abstract: Buschke-Lowenstein tumor (BLT) is a large exophytic lesion of the anogenital region with a clinically malignant aspect but a benign histology. Because of its low incidence, this pathology is exceptional in childhood. Surgical excision is the main therapeutic approach. Herein, we report a case of BLT successfully treated with imiquimod in a 2-year old boy. Young children with BLT should be offered a chance of medical treatment before extensive surgical destruction is used.
authors.affiliation: Dermatology Department, Habib Thameur Hospital, LR12SP03, Tunis, Tunisia.
authors.forename: Zaouak
authors.initials: Z
authors.lastname: Anissa
authors.affiliation: Dermatology Department, Habib Thameur Hospital, LR12SP03, Tunis, Tunisia.
authors.forename: Hammami-Ghorbel
authors.initials: HG
authors.lastname: Houda
authors.affiliation: Anatomopathology Department, Habib Thameur Hospital, LR12SP03, Tunis, Tunisia.
authors.forename: Koubaa
authors.initials: K
authors.lastname: Wafa
authors.affiliation: Dermatology Department, Habib Thameur Hospital, LR12SP03, Tunis, Tunisia.
authors.forename: Midassi
authors.initials: M
authors.lastname: Olfa
authors.affiliation: Dermatology Department, Habib Thameur Hospital, LR12SP03, Tunis, Tunisia.
authors.forename: Benmously-Mlika
authors.initials: BM
authors.lastname: Rym
authors.affiliation: Anatomopathology Department, Habib Thameur Hospital, LR12SP03, Tunis, Tunisia.
authors.forename: Debbiche
authors.initials: D
authors.lastname: Achraf
authors.affiliation: Dermatology Department, Habib Thameur Hospital, LR12SP03, Tunis, Tunisia.
authors.forename: Fenniche
authors.initials: F
authors.lastname: Samy
mesh_terms: D000287:Administration, Topical; D000634:Aminoquinolines / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001005:Anus Neoplasms / Q000188:drug therapy* / Q000473:pathology; D001706:Biopsy; D062688:Buschke-Lowenstein Tumor / Q000188:drug therapy* / Q000473:pathology; D002675:Child, Preschool; D006801:Humans; D000077271:Imiquimod; D008297:Male; D012074:Remission Induction; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod
keywords: Buschke-Löwenstein tumor; anal; child; imiquimod; safety; treatment