title: Noninvasive vascular imaging of ruptured retinal arterial macroaneurysms by Doppler optical coherence tomography.
abstract: BACKGROUND
  To describe Doppler optical coherence tomography (OCT) imaging of ruptured retinal arterial macroaneurysms (RAMs).
  
  
  METHODS
  Four eyes of four patients with ruptured RAMs were prospectively studied. Vascular imaging was obtained using swept-source Doppler OCT, and compared with indocyanine green angiography images.
  
  
  RESULTS
  En face projection of Doppler OCT images clearly showed RAMs at the corresponding locations of lesions in the indocyanine green angiography images. In Doppler OCT images, RAMs were located in the inner retina in three eyes and in the medium layer of the retina in one eye. In one eye, detection of RAMs by standard OCT was difficult because of the presence of inner retinal hemorrhage. In one eye, disappearance of blood flow after direct laser photocoagulation could be confirmed by Doppler OCT images.
  
  
  CONCLUSIONS
  Doppler OCT imaging may potentially function as a noninvasive complementary procedure with indocyanine green angiography.
authors.affiliation: Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, 3-20-1 Chuo, Ami, Inashiki, Ibaraki, 3000395, Japan. m-miura@tokyo-med.ac.jp.|Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku, Tokyo, 1600023, Japan. m-miura@tokyo-med.ac.jp.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miura
authors.affiliation: Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, 3-20-1 Chuo, Ami, Inashiki, Ibaraki, 3000395, Japan. gmura0815@yahoo.co.jp.|Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku, Tokyo, 1600023, Japan. gmura0815@yahoo.co.jp.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Muramatsu
authors.affiliation: Computational Optics Group, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 3058571, Japan. youngjoo.hong@optlab2.bk.tsukuba.ac.jp.
authors.forename: Young-Joo
authors.initials: YJ
authors.lastname: Hong
authors.affiliation: Computational Optics Group, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 3058571, Japan. yasuno@optlab2.bk.tsukuba.ac.jp.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Yasuno
authors.affiliation: Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, 3-20-1 Chuo, Ami, Inashiki, Ibaraki, 3000395, Japan. mmiuratokyo@gmail.com.|Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku, Tokyo, 1600023, Japan. mmiuratokyo@gmail.com.
authors.forename: Ayako
authors.initials: A
authors.lastname: Itami
authors.affiliation: Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, 3-20-1 Chuo, Ami, Inashiki, Ibaraki, 3000395, Japan. iwaponex@tokyo-med.ac.jp.|Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku, Tokyo, 1600023, Japan. iwaponex@tokyo-med.ac.jp.
authors.forename: Takuya
authors.initials: T
authors.lastname: Iwasaki
authors.affiliation: Department of Ophthalmology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku, Tokyo, 1600023, Japan. goto1115@tokyo-med.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Goto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000175:diagnosis* / Q000601:surgery; D004396:Coloring Agents; D004301:Doppler Effect; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D021621:Imaging, Three-Dimensional; D007208:Indocyanine Green; D017075:Laser Coagulation; D008297:Male; D011446:Prospective Studies; D012161:Retinal Artery / Q000473:pathology*; D012166:Retinal Hemorrhage / Q000175:diagnosis* / Q000601:surgery; D041623:Tomography, Optical Coherence
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green