title: Comorbidities in patients with psoriatic arthritis: a comparison with rheumatoid arthritis and psoriasis.
abstract: OBJECTIVE
  Psoriatic arthritis (PsA) is a chronic, inflammatory disease. The purpose of this study was to examine the association between PsA and comorbid conditions. This is the first study to investigate comorbid diseases in PsA in Turkey.
  
  
  METHODS
  This study was performed under the auspices of the Anatolian Group for the Assessment in Rheumatic Diseases (ANGARD) and involved participation by six university research hospitals. Patients diagnosed with and treated for PsA on the basis of clinical, radiological and laboratory findings and expert opinion were monitored using standardized examination methods and jointly prepared forms. Clinical status, accompanying systemic diseases and surgical history were recorded.
  
  
  RESULTS
  One hundred and seventy-three patients with PsA (75 male, 98 female, mean age 41.8) and 138 patients with rheumatoid arthritis (RA) (17 male, 121 female, mean age 48.6) and 67 with psoriasis (PsO) (43 male, 24 female, mean age 36.1) were included in the study. No accompanying disease was determined in 72.8% of PsA, 50.0% of RA and 80.6% of PsO groups. In regression analysis, patients with PsA had higher risk for cataract/glaucoma surgery (odds ratio [OR] = 11.99; 95% CI 1.36-105.4, P = 0.025) compared to patients with RA, and higher risk for hypertension (HT) (OR = 4.26; 95% CI 1.27-14.23, P = 0.018) compared to the patients with PsO.
  
  
  CONCLUSIONS
  Patients with PsA have relatively lower frequency of comorbidities like diabetes mellitus, HT and cataract/glaucoma surgery compared to the patients with RA. The increased risk for having cataract/glaucoma surgery in RA compared to PsA may be particularly attributed to the more prevalent glucocorticoid use in RA.
authors.affiliation: Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Nas
authors.affiliation: Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Karkucak
authors.affiliation: Erenkoy Physical Medicine and Rehabilitation Hospital, Faculty of Health Sciences, Association of Public Hospitals Northern Anatolian Region of Istanbul, Istanbul, Turkey.
authors.forename: Bekir
authors.initials: B
authors.lastname: Durmus
authors.affiliation: Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Turkey.
authors.forename: Saliha
authors.initials: S
authors.lastname: Karatay
authors.affiliation: Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
authors.forename: Erhan
authors.initials: E
authors.lastname: Capkın
authors.affiliation: Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Firat University, Elazig, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Kaya
authors.affiliation: Department of Dermatology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
authors.forename: Derya
authors.initials: D
authors.lastname: Ucmak
authors.affiliation: Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
authors.forename: Zeynel Abidin
authors.initials: ZA
authors.lastname: Akar
authors.affiliation: Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
authors.forename: Remzi
authors.initials: R
authors.lastname: Cevik
authors.affiliation: Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
authors.forename: Erkan
authors.initials: E
authors.lastname: Kilic
authors.affiliation: Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
authors.forename: Gamze
authors.initials: G
authors.lastname: Kilic
authors.affiliation: Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
authors.forename: Salih
authors.initials: S
authors.lastname: Ozgocmen
mesh_terms: D000328:Adult; D015535:Arthritis, Psoriatic / Q000175:diagnosis / Q000453:epidemiology*; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000453:epidemiology*; D016009:Chi-Square Distribution; D015897:Comorbidity; D016208:Databases, Factual; D005260:Female; D006785:Hospitals, University; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011565:Psoriasis / Q000175:diagnosis / Q000453:epidemiology*; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology
keywords: comorbid diseases; psoriasis; psoriatic arthritis; rheumatoid arthritis