title: Osteomesopyknosis--a benign axial hyperostosis that can mimic metastatic disease.
abstract: We report two cases of an axial osteosclerosis with histopathologic findings of osteomesopyknosis in siblings. Osteomesopyknosis is a benign hereditary osteosclerosis that can show a radiologic pattern similar to blastic metastatic disease. The aim of this article is to inform radiologists about the existence of this benign condition and its various radiologic manifestations. Therefore, we discuss the principal differential diagnosis and point out the key imaging findings of osteomesopyknosis in order to avoid overdiagnosis in future cases.
authors.affiliation: Radiology Department of the University Hospital, Hospital Universitario Puerta del Mar, Cádiz, Spain. evamarie.heursen@gmail.com.
authors.forename: Eva-Marie
authors.identifier: http://orcid.org/0000-0003-4492-4697
authors.initials: EM
authors.lastname: Heursen
authors.affiliation: Radiology Department of the University Hospital, Hospital Universitario Puerta del Mar, Cádiz, Spain.
authors.forename: María del Carmen
authors.initials: Mdel C
authors.lastname: González Partida
authors.affiliation: Radiology Department of the University Hospital, Hospital Universitario Puerta del Mar, Cádiz, Spain.
authors.forename: José
authors.initials: J
authors.lastname: Paz Expósito
authors.affiliation: Radiology Department of the University Hospital, Hospital Universitario Puerta del Mar, Cádiz, Spain.
authors.forename: Federico
authors.initials: F
authors.lastname: Navarro Díaz
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015576:Hyperostosis / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010026:Osteosclerosis / Q000175:diagnosis*; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: Axial osteosclerosis; Osteomesopyknosis; Spine