title: New fluorescence probe for Fe³⁺ with bis-rhodamine and its application as a molecular logic gate.
abstract: A bis-rhodamine based fluorescent probe R1 for naked-eye detection of Fe(3+) with enhanced sensitivity compared to a mono-rhodamine derivative that shows selectivity for Hg(2+), has been synthesized. The 1:1 stoichiometric structure of R1 and Fe(3+) is confirmed using a Job's plot estimation and density functional theory calculations. The reversibility of R1 is verified through its spectral response toward Fe(3+) and S(2-) titration experiments. Using Fe(3+) and S(2-) as chemical inputs and the fluorescence intensity signal as outputs, R1 can be utilized as an INHIBIT logic gate at molecular level. Fluorescent imaging for Fe(3+) in living HL-7702 cells have also been successfully performed.
authors.affiliation: State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Key Lab of Fiber Modification & Functional Fiber of Tianjin, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, Tianjin Polytechnic University, Tianjin 300387, China. Electronic address: yanfanyong@tjpu.edu.cn.
authors.forename: Fanyong
authors.initials: F
authors.lastname: Yan
authors.affiliation: State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Key Lab of Fiber Modification & Functional Fiber of Tianjin, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, Tianjin Polytechnic University, Tianjin 300387, China.
authors.forename: Tancheng
authors.initials: T
authors.lastname: Zheng
authors.affiliation: State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Key Lab of Fiber Modification & Functional Fiber of Tianjin, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, Tianjin Polytechnic University, Tianjin 300387, China.
authors.forename: Shanshan
authors.initials: S
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Key Lab of Fiber Modification & Functional Fiber of Tianjin, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, Tianjin Polytechnic University, Tianjin 300387, China.
authors.forename: Dechao
authors.initials: D
authors.lastname: Shi
authors.affiliation: State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Key Lab of Fiber Modification & Functional Fiber of Tianjin, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, Tianjin Polytechnic University, Tianjin 300387, China.
authors.forename: Ziyi
authors.initials: Z
authors.lastname: Han
authors.affiliation: State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Key Lab of Fiber Modification & Functional Fiber of Tianjin, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, Tianjin Polytechnic University, Tianjin 300387, China.
authors.forename: Siyushan
authors.initials: S
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Hollow Fiber Membrane Materials and Processes, Key Lab of Fiber Modification & Functional Fiber of Tianjin, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, Tianjin Polytechnic University, Tianjin 300387, China.
authors.forename: Li
authors.initials: L
authors.lastname: Chen
mesh_terms: D002460:Cell Line; D005290:Ferric Compounds / Q000737:chemistry; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D007501:Iron / Q000032:analysis* / Q000737:chemistry; D057054:Molecular Imaging / Q000379:methods; D015336:Molecular Probe Techniques; D015335:Molecular Probes / Q000737:chemistry*; D015394:Molecular Structure; D012235:Rhodamines / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013455:Sulfur / Q000737:chemistry
chemical_list: D005290:Ferric Compounds; D005456:Fluorescent Dyes; D015335:Molecular Probes; D012235:Rhodamines; D013455:Sulfur; D007501:Iron
keywords: Fe(3+); Fluorescent probe; Logic gate; Rhodamine