title: Foveal Serous Retinal Detachment in Juvenile Idiopathic Arthritis-associated Uveitis.
abstract: OBJECTIVE
  In juvenile idiopathic arthritis (JIA)-associated uveitis complicated by foveal serous retinal detachment (FSRD), we documented the relationship between best corrected visual acuity (BCVA), level of anterior chamber flare and OCT features.
  
  
  METHODS
  Nine children (15 eyes) with FSRD were identified among 38 children with JIA-associated maculopathy. Outcome measures included BCVA, ocular inflammatory activity quantified by laser flare photometry and the macular profile analyzed by OCT.
  
  
  RESULTS
  The diagnosis of FSRD led to intensification of the treatment using subtenon's injection of triamcinolone or systemic immunomodulatory therapy. The improvement of BCVA at presentation (0.46 logMAR) was significant at 36 months follow-up (0.15 logMAR). The resolution of FSRD along with visual improvement (p = 0.0032) correlated with improvement in anterior chamber flare (p = 0.01).
  
  
  CONCLUSIONS
  FSRD is a complication of chronic JIA-associated uveitis that responds well to intensification of immunomodulation. Visual improvement is correlated with FSRD resolution and with flare photometry values.
authors.affiliation: a Department of Ophthalmology , University of Paris VI, Pitié-Salpêtrière Hospital , Paris , France .
authors.forename: Feng
authors.initials: F
authors.lastname: Liang
authors.affiliation: a Department of Ophthalmology , University of Paris VI, Pitié-Salpêtrière Hospital , Paris , France .
authors.forename: Celine
authors.initials: C
authors.lastname: Terrada
authors.affiliation: a Department of Ophthalmology , University of Paris VI, Pitié-Salpêtrière Hospital , Paris , France .
authors.forename: Ghislaine
authors.initials: G
authors.lastname: Ducos de Lahitte
authors.affiliation: b Unit of Immuno-Hematology and Pediatric Rheumatology , Necker-Enfants Malades Hospital , Paris , France .
authors.forename: Pierre
authors.initials: P
authors.lastname: Quartier
authors.affiliation: a Department of Ophthalmology , University of Paris VI, Pitié-Salpêtrière Hospital , Paris , France .
authors.forename: Phuc
authors.initials: P
authors.lastname: Lehoang
authors.affiliation: c Department of Ophthalmology , Wilmer Eye Institute, Johns Hopkins University School of Medicine , and.|d Department of Epidemiology , Johns Hopkins University Bloomberg School of Public Health , Baltimore , Maryland , USA.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Thorne
authors.affiliation: a Department of Ophthalmology , University of Paris VI, Pitié-Salpêtrière Hospital , Paris , France .
authors.forename: Bahram
authors.initials: B
authors.lastname: Bodaghi
mesh_terms: D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000473:pathology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D005584:Fovea Centralis; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D010783:Photometry; D012163:Retinal Detachment / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D058471:Subretinal Fluid; D041623:Tomography, Optical Coherence; D014606:Uveitis, Anterior / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D007166:Immunosuppressive Agents
keywords: Flare; OCT; foveal serous retinal detachment; juvenile idiopathic arthritis; uveitis