title: Persistent Infection Because of Pandoraea sputorum in a Young Cystic Fibrosis Patient Resistant to Antimicrobial Treatment.
abstract: We report the case of a 13-year-old boy with cystic fibrosis with a pulmonary exacerbation concomitant to the first isolation of Pandoraea sputorum. The imipenem and trimethoprim-sulfamethoxazole treatments failed, with persistence of the bacteria, bronchial congestion and a decline in lung function. Pandoraea sp. is rarely isolated, with only 10 cases reported in France in 2011.
authors.affiliation: From the *CHU de Bordeaux, Service des Maladies Infectieuses et Tropicales, Bordeaux, France; †CHU de Bordeaux, Service de pneumologie pédiatrique, CRCM Pédiatrique, Bordeaux, France; ‡CIC 0005, Inserm, Centre d'investigation clinique pédiatrique, Hôpital Pellegrin-enfants, Bordeaux, France; and §CHU de Bordeaux, Laboratoire de Bactériologie, Bordeaux, France.
authors.forename: Mathilde
authors.initials: M
authors.lastname: Pugès
authors.forename: Stéphane
authors.initials: S
authors.lastname: Debelleix
authors.forename: Michael
authors.initials: M
authors.lastname: Fayon
authors.forename: Francis
authors.initials: F
authors.lastname: Mégraud
authors.forename: Philippe
authors.initials: P
authors.lastname: Lehours
mesh_terms: D000293:Adolescent; D000890:Anti-Infective Agents / Q000494:pharmacology / Q000627:therapeutic use; D042521:Burkholderiaceae / Q000187:drug effects / Q000302:isolation & purification; D003550:Cystic Fibrosis / Q000150:complications*; D024881:Drug Resistance, Bacterial; D016905:Gram-Negative Bacterial Infections; D006801:Humans; D008297:Male
chemical_list: D000890:Anti-Infective Agents