title: Three-Component Cascade Reactions with 2,3-Diketoesters: A Novel Metal-Free Synthesis of 5-Vinyl-pyrrole and 4-Hydroxy-indole Derivatives.
abstract: 5-Vinyl-pyrrole and 4-hydroxy-indole derivatives are synthesized by metal-free aldol/cyclization/aromatization cascade reactions of in situ generated enamines with 2,3-diketoesters. This convenient atom-economical process produces multifunctional pyrrole and indole products in moderate to good yields.
authors.affiliation: †School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, P. R. of China.|‡Department of Chemistry, The University of Texas at San Antonio, San Antonio, Texas 78249, United States.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Sha
authors.affiliation: ‡Department of Chemistry, The University of Texas at San Antonio, San Antonio, Texas 78249, United States.
authors.forename: Hadi
authors.initials: H
authors.lastname: Arman
authors.affiliation: ‡Department of Chemistry, The University of Texas at San Antonio, San Antonio, Texas 78249, United States.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Doyle