title: [TESTICULAR DEFICIT SYNDROME IN MEN WITH TYPE 2 DIABETES AND OBESITY].
abstract: The aim of the study was to examine the level of sex and pituitary hormones in men of older age groups suffering from type 2 diabetes with visceral-abdominal obesity and without it. The study involved 89 men aged 46-76 years with type-2 diabetes. We analyzed the levels of sex hormones (total and free testosterone, estradiol) and lutenizing hormone levels in the blood of men in the survey, depending on the presence/absence of obesity and androgen deficiency. Average levels total and free testosterone were significantly reduced in patients of all groups surveyed. The lowest level of androgens observed in patients with type 2 diabetes, obesity and androgen. Mid E2 levels only in patients with type 2 diabetes and obesity showed a tendency to increase. Coefficient of T/E2 was significantly reduced in patients with type 2 diabetes and obesity (63,00±8,20) and to a lesser extent in patients with type 2 diabetes without obesity (112,40±8,16) compared the control group (136,40±11,30). The results indicate the presence of not only absolute, but relative androgendeficiency in men with type 2 diabetes.
authors.affiliation: SI "V.P. Komissarenko Institute of Endocrinology and Metabolism NAMS of Ukraine", Kyiv, Ukraine.
authors.forename: V
authors.initials: V
authors.lastname: Luchytskyy
mesh_terms: D000368:Aged; D000728:Androgens / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000473:pathology; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000473:pathology; D013733:Testicular Diseases / Q000097:blood* / Q000473:pathology; D013739:Testosterone / Q000097:blood*
chemical_list: D000728:Androgens; D012739:Gonadal Steroid Hormones; D013739:Testosterone