title: Independent Determinants of Maternal and Fetal Outcomes in a Sample of Pregnant Outpatients With Normal Blood Pressure, Chronic Hypertension, Gestational Hypertension, and Preeclampsia.
abstract: The aim of this retrospective study was to evaluate the main independent prognostic factors of negative maternal and fetal outcomes in a relatively large sample of pregnant outpatients (N=906) who were normotensive or affected by chronic hypertension, gestational hypertension, or preeclampsia. Among the studied parameters, the ones significantly associated with negative maternal outcomes were a diagnosis of preeclampsia (vs other forms of hypertension or normotension) and higher serum uric acid level, while antihypertensive treatment, number of previous deliveries, and blood pressure (BP) control at deliveries seemed to be protective. Regarding negative fetal outcomes, the parameters significantly associated with a negative maternal outcome were a diagnosis of preeclampsia (vs other forms of hypertension or normotension) and mother pre-pregnancy body mass index, while antihypertensive treatment and BP control at delivery seemed to be protective. Specific patient characteristics should help to predict the risk of negative maternal and fetal outcomes.
authors.affiliation: Medical and Surgery Sciences Department, University of Bologna, Bologna, Italy.
authors.forename: Arrigo F G
authors.initials: AF
authors.lastname: Cicero
authors.affiliation: Medical and Surgery Sciences Department, University of Bologna, Bologna, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Degli Esposti
authors.affiliation: Medical and Surgery Sciences Department, University of Bologna, Bologna, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Immordino
authors.affiliation: Medical and Surgery Sciences Department, University of Bologna, Bologna, Italy.
authors.forename: Martino
authors.initials: M
authors.lastname: Morbini
authors.affiliation: Medical and Surgery Sciences Department, University of Bologna, Bologna, Italy.
authors.forename: Cristina
authors.initials: C
authors.lastname: Baronio
authors.affiliation: Medical and Surgery Sciences Department, University of Bologna, Bologna, Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Rosticci
authors.affiliation: Medical and Surgery Sciences Department, University of Bologna, Bologna, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Borghi
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D007558:Italy / Q000453:epidemiology; D010045:Outpatients; D011225:Pre-Eclampsia / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D014527:Uric Acid / Q000097:blood
chemical_list: D000959:Antihypertensive Agents; D014527:Uric Acid