title: Advances in the management of gastrointestinal cancers--an upcoming role of immune checkpoint blockade.
abstract: Gastrointestinal cancers are a group of highly aggressive malignancies, and novel therapeutic strategies with higher clinical efficacy are being actively sought. 'Immunotherapy' is now emerging as one such promising strategy for the treatment of these tumors. This article briefly reviews the recent advances that utilize targeting of immune checkpoint pathways, in the management of gastrointestinal malignancies.
authors.affiliation: Division of Medical Oncology, Department of Medicine, University of Kentucky Markey Cancer Center, Lexington, KY, 40536, USA. ggoel.uky@gmail.com.
authors.forename: Gaurav
authors.initials: G
authors.lastname: Goel
authors.affiliation: Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, 5150 Centre Avenue, Pittsburgh, PA, 15232, USA. sunw@upmc.edu.
authors.forename: Weijing
authors.initials: W
authors.lastname: Sun
mesh_terms: D005770:Gastrointestinal Neoplasms / Q000276:immunology*; D006801:Humans; D007167:Immunotherapy / Q000379:methods*