title: Effects of Dabigatran on the Resolution of Left Ventricular Thrombus after Acute Myocardial Infarction.
abstract: Left ventricular thrombus (LVT) after acute myocardial infarction (AMI) is a risk factor for embolic complications. Although warfarin has traditionally been used to treat LVT, it has relevant disadvantages that limit its use. We herein describe the case of a 78-year-old man with AMI who had a history of paroxysmal atrial fibrillation. Following 10 days of urgent coronary reperfusion therapy, transthoracic echocardiography revealed a moderately sized LVT in the apex, which subsequently disappeared after 18 days of treatment with dabigatran. This case demonstrates that dabigatran may represent an alternative to warfarin as a therapeutic option in patients with LVT after AMI.
authors.affiliation: Department of Cardiology, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Japan.
authors.forename: Norihiko
authors.initials: N
authors.lastname: Ohashi
authors.forename: Takenori
authors.initials: T
authors.lastname: Okada
authors.forename: Mio
authors.initials: M
authors.lastname: Uchida
authors.forename: Michitaka
authors.initials: M
authors.lastname: Amioka
authors.forename: Mai
authors.initials: M
authors.lastname: Fujiwara
authors.forename: Shunichi
authors.initials: S
authors.lastname: Kaseda
mesh_terms: D000368:Aged; D000991:Antithrombins / Q000627:therapeutic use*; D002637:Chest Pain / Q000188:drug therapy / Q000209:etiology*; D000069604:Dabigatran / Q000627:therapeutic use*; D004452:Echocardiography; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000188:drug therapy; D015425:Myocardial Reperfusion / Q000379:methods; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000209:etiology*
chemical_list: D000991:Antithrombins; D000069604:Dabigatran