title: A rare case of esophageal cancer (T2N0) with a solitary cerebellar metastasis.
abstract: A 72-year-old man with a history of distal gastrectomy was diagnosed with esophageal cancer (EC). A subtotal esophagectomy and the residual total gastrectomy were performed via a right-sided thoracotomy and laparotomy with D2 lymph node dissection followed by reconstruction with a retrosternal right colonic interposition. The pathological diagnosis was Mt, 65 mm, moderately differentiated squamous cell carcinoma, pT2, ly0, v2, pN0, sM0, pStage II. The patient suddenly developed neurological symptoms 10 days after the operation, and brain magnetic resonance imaging detected a single solid left cerebellar tumor. This tumor was completely excised, and pathological diagnosis confirmed the tumor as an EC metastasis. He received adjuvant chemotherapy with cisplatin + 5-fluorouracil. Seven months later, he developed multiple brain metastases; however, no evidence of local recurrence or other metastatic sites was found. He died 8 months after the surgery. Solitary cerebellar metastasis from EC in which the primary tumor is T2N0 is rare, and the mechanism of this metastatic pattern is of particular interest. Our case study suggests that even if the primary tumor is in the limited stage and other metastatic sites are not identified at presentation, it seems reasonable to perform preoperative imaging of the brain for all patients with EC.
authors.affiliation: Department of Surgery, Funabashi Central Hospital of Social Insurance, 6-13-10 Kaijin, Funabashi, Chiba, 273-8556, Japan. deigo_77@yahoo.co.jp.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ohtsuka
authors.affiliation: Department of Neurosurgery, Funabashi Municipal Medical Center, Funabashi, Chiba, Japan.
authors.forename: Kazumi
authors.initials: K
authors.lastname: Hatayama
authors.affiliation: Department of Pathology, Funabashi Central Hospital of Social Insurance, Funabashi, Chiba, Japan.
authors.forename: Teisuke
authors.initials: T
authors.lastname: Komatsu
authors.affiliation: Department of Surgery, Funabashi Central Hospital of Social Insurance, 6-13-10 Kaijin, Funabashi, Chiba, 273-8556, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ogasawara
authors.affiliation: Department of Surgery, Funabashi Central Hospital of Social Insurance, 6-13-10 Kaijin, Funabashi, Chiba, 273-8556, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Shida
authors.affiliation: Department of Surgery, Funabashi Central Hospital of Social Insurance, 6-13-10 Kaijin, Funabashi, Chiba, 273-8556, Japan.
authors.forename: Shigeharu
authors.initials: S
authors.lastname: Nakano
authors.affiliation: Department of Surgery, Funabashi Central Hospital of Social Insurance, 6-13-10 Kaijin, Funabashi, Chiba, 273-8556, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Nomura
authors.affiliation: Department of Surgery, Funabashi Central Hospital of Social Insurance, 6-13-10 Kaijin, Funabashi, Chiba, 273-8556, Japan.
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Sato
authors.affiliation: Department of Surgery, Funabashi Central Hospital of Social Insurance, 6-13-10 Kaijin, Funabashi, Chiba, 273-8556, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Takahashi
authors.affiliation: Department of Pathology, Teikyo University School of Medicine, Itabashi, Tokyo, Japan.
authors.forename: Fukuo
authors.initials: F
authors.lastname: Kondo
keywords: Brain metastasis; Cerebellar metastasis; Esophageal cancer; Solitary metastasis