title: Formation of multiple pulmonary nodules during treatment with leflunomide.
abstract: Pulmonary involvement is one of the extra-articular manifestations of rheumatoid arthritis and can be due to the disease itself or secondary to the medications used in order to treat it. We report the case of a 60-year-old woman who had been diagnosed with rheumatoid arthritis and developed multiple pulmonary nodules during treatment with leflunomide.
authors.affiliation: Federal University of Pará, Belém, Brazil.
authors.forename: Gilberto Toshikawa
authors.initials: GT
authors.lastname: Yoshikawa
authors.affiliation: Federal University of Pará, Belém, Brazil.
authors.forename: George Alberto da Silva
authors.initials: GA
authors.lastname: Dias
authors.affiliation: Federal University of Pará, Belém, Brazil.
authors.forename: Satomi
authors.initials: S
authors.lastname: Fujihara
authors.affiliation: Federal University of Pará, Belém, Brazil.
authors.forename: Luigi Ferreira e
authors.initials: LF
authors.lastname: Silva
authors.affiliation: Federal University of Pará, Belém, Brazil.
authors.forename: Lorena de Britto Pereira
authors.initials: Lde B
authors.lastname: Cruz
authors.affiliation: Federal University of Pará, Belém, Brazil.
authors.forename: Hellen Thais
authors.initials: HT
authors.lastname: Fuzii
authors.affiliation: Federal University of Pará, Belém, Brazil.
authors.forename: Roberta Vilela Lopes
authors.initials: RV
authors.lastname: Koyama
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000009:adverse effects*; D000077339:Leflunomide; D008875:Middle Aged; D055613:Multiple Pulmonary Nodules / Q000139:chemically induced* / Q000473:pathology; D012218:Rheumatoid Nodule / Q000139:chemically induced* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D018501:Antirheumatic Agents; D007555:Isoxazoles; D000077339:Leflunomide