title: Oleaginous yeast: a value-added platform for renewable oils.
abstract: Yeast single cell oil (SCO) is a non-crop-based, renewable oil source that can be used for the production of bio-based oleochemicals. Stand-alone production of SCO for oleochemicals is currently not cost-competitive because lower-cost alternatives from petroleum and crop-based resources are available. Utilizing low-valued nutrient sources, implementing cost-efficient downstream processes and adopting biotechnological advancements such as systems biology and metabolic engineering could prove valuable in making an SCO platform a reality in the emerging bio-based economy. This review aims to consider key biochemical pathways for storage lipid synthesis, possible pathways for SCO yield improvement, previously used bioprocessing techniques for SCO production, challenges in SCO commercialization and advantages of adopting a renewable SCO platform.
authors.affiliation: a IGERT in Biorefining .|b Bioprocessing and Renewable Energy Laboratory, Department of Grain Science and Industry .
authors.forename: Kyle V
authors.initials: KV
authors.lastname: Probst
authors.affiliation: a IGERT in Biorefining .|c Department of Chemical Engineering , and.
authors.forename: Leslie R
authors.initials: LR
authors.lastname: Schulte
authors.affiliation: d Department of Biochemistry and Molecular Biophysics , Kansas State University , Manhattan , KS , USA.
authors.forename: Timothy P
authors.initials: TP
authors.lastname: Durrett
authors.affiliation: c Department of Chemical Engineering , and.
authors.forename: Mary E
authors.initials: ME
authors.lastname: Rezac
authors.affiliation: a IGERT in Biorefining .|c Department of Chemical Engineering , and.
authors.forename: Praveen V
authors.initials: PV
authors.lastname: Vadlani
mesh_terms: D005285:Fermentation; D060847:Metabolic Engineering; D009821:Oils / Q000378:metabolism*; D014280:Triglycerides / Q000378:metabolism; D015003:Yeasts / Q000378:metabolism*
chemical_list: D009821:Oils; D014280:Triglycerides
keywords: Biofuel; fatty acid; fermentation; integrated biorefinery; lignocellulosic biomass; lipid; oleochemical; single cell oil; triacylglyceride