title: Identification and antifeedant activities of limonoids from Azadirachta indica.
abstract: Four new limonoids, azadiraindins A-D (1-4, resp.), together with seven known analogs, were isolated from the MeOH extract of Azadirachta indica. The structures of 1-4 were elucidated by NMR and MS spectroscopic analyses, and the relative configuration of 1 was determined by single-crystal X-ray crystallography. The compounds isolated in comparatively large amount were evaluated for their antifeedant activities against Plutella xylostella; the antifeedant rate of 10 was 90.6% and the corrected mortality of 8 was 79.2%.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China, (phone: +86-871-65223327; fax: +86-871-65223255).
authors.forename: Yu-Xin
authors.initials: YX
authors.lastname: Yan
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China, (phone: +86-871-65223327; fax: +86-871-65223255).
authors.forename: Jie-Qing
authors.initials: JQ
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China, (phone: +86-871-65223327; fax: +86-871-65223255).
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China, (phone: +86-871-65223327; fax: +86-871-65223255).
authors.forename: Jin-Xiong
authors.initials: JX
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China, (phone: +86-871-65223327; fax: +86-871-65223255).
authors.forename: Jian-Chao
authors.initials: JC
authors.lastname: Chen
authors.affiliation: Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, P. R. China.
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China, (phone: +86-871-65223327; fax: +86-871-65223255).
authors.forename: Lin
authors.initials: L
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, P. R. China, (phone: +86-871-65223327; fax: +86-871-65223255). mhchiu@mail.kib.ac.cn.
authors.forename: Ming-Hua
authors.initials: MH
authors.lastname: Qiu
mesh_terms: D000818:Animals; D031601:Azadirachta / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005247:Feeding Behavior / Q000187:drug effects*; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D007915:Lepidoptera / Q000187:drug effects*; D036701:Limonins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008958:Models, Molecular; D008968:Molecular Conformation
chemical_list: D007306:Insecticides; D036701:Limonins
keywords: Antifeedants; Azadirachta indica; Azadiraindins A - D; Limonoids