title: Livedo Reticularis: A Presenting Sign of Escherichia Coli Sepsis in a Newborn.
abstract: Livedo reticularis is a red cutaneous netlike pattern that is caused by abnormalities of the microvascularization and can be associated with many other potential systemic etiologies. We describe a case of a newborn that presented with livedo reticularis on his first day of life without any obvious systemic signs. The livedo reticularis was associated with Escherichia Coli K1 meningitis as revealed by laboratory tests. Clinical infectious signs developed a few hours later. Despite appropriate antibiotics therapy, he died on his second day because of sepsis and disseminated intravascular coagulation. Cerebrospinal fluid culture, blood culture, and culture of samples from trachea showed the presence of Escherichia Coli serotype K1 with many virulence determinants.
  
  
  CONCLUSIONS
  In newborn, livedo reticularis must not be considered as physiological, but as a potential sign of unknown severe bacterial infection. Thus, the presence of livedo reticularis must require urgent laboratory tests.
authors.affiliation: a Faculté de Médecine Pierre et Marie Curie , Paris , France.
authors.forename: Anne-Aurélie
authors.initials: AA
authors.lastname: Lopes
authors.affiliation: b Service de Néonatologie, Assistance Publique-Hôpitaux de Paris, Hôpital Armand Trousseau , Paris , France.
authors.forename: Valérie
authors.initials: V
authors.lastname: Champion
authors.affiliation: c Service de Microbiologie, Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré , Paris , France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Bonacorsi
authors.affiliation: b Service de Néonatologie, Assistance Publique-Hôpitaux de Paris, Hôpital Armand Trousseau , Paris , France.
authors.forename: Delphine
authors.initials: D
authors.lastname: Mitanchez
mesh_terms: D004211:Disseminated Intravascular Coagulation / Q000382:microbiology; D004927:Escherichia coli Infections / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D007231:Infant, Newborn; D054068:Livedo Reticularis / Q000209:etiology*; D008297:Male; D008581:Meningitis / Q000382:microbiology; D018805:Sepsis / Q000382:microbiology*
keywords: Escherichia Coli K1; Livedo reticularis; meningitis; newborn; sepsis