title: Early gastric cancer with spreading to heterotopic gastric glands in the submucosa: a case report and review of the literature.
abstract: We report two cases of early gastric cancer (EGC) with spreading to heterotopic gastric glands (HGG). The first case was a submucosal-tumor-like EGC and proximal gastrectomy was performed. The second case was a slightly elevated EGC and endoscopic submucosal dissection was performed. In both cases, pathological results showed adenocarcinoma spreading to the HGG in the submucosa. The depth of cancer was diagnosed as intramucosal carcinoma because cancer was limited to the epithelium of HGG without invasion to the submucosal stroma. There is no clear guideline concerning the management of early gastric cancers with spreading to heterotopic gastric glands.
authors.affiliation: Division of Endoscopy, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi, Suntogun, Shizuoka, 411-8777, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Hagiwara
authors.forename: Naomi
authors.initials: N
authors.lastname: Kakushima
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Imai
authors.forename: Masaki
authors.initials: M
authors.lastname: Tanaka
authors.forename: Toshitatsu
authors.initials: T
authors.lastname: Takao
authors.forename: Kinichi
authors.initials: K
authors.lastname: Hotta
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Yamaguchi
authors.forename: Kohei
authors.initials: K
authors.lastname: Takizawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Matsubayashi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ono
authors.forename: Takuma
authors.initials: T
authors.lastname: Oishi
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakajima
mesh_terms: D002828:Choristoma / Q000150:complications / Q000473:pathology*; D005753:Gastric Mucosa / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D013272:Stomach Diseases / Q000150:complications / Q000473:pathology*; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology*