title: EARLY EXPERIENCE OF ENDOVASCULAR TREATMENT OF PERIPHERAL VASCULAR DISEASE.
abstract: BACKGROUND
  Atherosclerotic peripheral arterial disease (PAD) is prevalent affecting up to 16% of the population aged 55 years or older. Endovascular intervention for the treatment of limb ischemia has become the first line therapy but in Pakistan it is in embryonic stage due to dearth of trained persons and dedicated centres. This study was conducted to evaluate procedural success and early outcome of endovascular treatment of peripheral vascular disease.
  
  
  METHODS
  A prospective single arm multicentre study was conducted at the National Institute of Cardiovascular Disease and National Medical Centre, Karachi, Pakistan from January 2013 to June 2014. A total of 25 patients were enrolled in the study that underwent endovascular treatment. Out of 25 patients 23 (92%) had critical limb ischemia (CLI) as per TASC II classification (A to D) and 2 (8%) had carotid lesion with history of TIA. Patients of acute limb ischemia and stroke were excluded. Ankle brachial index (ABI) was classified as normal (0.9-1.3), mild (0.7-0.9), moderate (0.4-0.69), severe. (<0.4). Outcome was taken as immediate success and symptoms, amputation of limb among CLI patients and incidence of stroke in patients with carotid artery lesion at end of six months.
  
  
  RESULTS
  Among aortoiliac, femoropopliteal and tibioperoneal lesions, tibioperoneal lesions at six months were found to be more symptomatic 6 (86%) and amputation 4 (57%). Two carotid lesions at follow up were asymptomatic without stroke.
  
  
  CONCLUSIONS
  Endovascular treatment of peripheral vascular lesions, i.e., aortoiliac, femoropopliteal tibioperoneal and carotid lesions were satisfactory in immediate outcome. Tibioperoneal lesions were more symptomatic and limb amputation at six months.
authors.forename: Taria
authors.initials: T
authors.lastname: Ashraf
authors.forename: Kamal
authors.initials: K
authors.lastname: Yousuf
authors.forename: Muhammad Tariq
authors.initials: MT
authors.lastname: Karim
mesh_terms: D000792:Angiography; D055109:Ankle Brachial Index; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D005263:Femoral Artery; D006801:Humans; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000175:diagnosis / Q000601:surgery*; D011150:Popliteal Artery; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome