title: The copper-catalyzed synthesis of β-trifluoromethylated acrylonitriles and trifluoromethyl-substituted 2H-azirines.
abstract: The direct assembly of acrylonitriles and valuable 2H-azirines from readily available starting materials is described. This novel alkyne difunctionalization reaction proceeded under mild reaction conditions. Considering the versatile roles of 2H-azirines, this work paves the way for further modification into various heterocycles.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, China. liangym@lzu.edu.cn.
authors.forename: Yu-Tao
authors.initials: YT
authors.lastname: He
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.forename: Jiahui
authors.initials: J
authors.lastname: Zhao
authors.forename: Xue-Yuan
authors.initials: XY
authors.lastname: Liu
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Xu
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
mesh_terms: D000181:Acrylonitrile / Q000138:chemical synthesis* / Q000737:chemistry; D001389:Azirines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D001389:Azirines; D006571:Heterocyclic Compounds; D005461:Fluorine; D003300:Copper; D000181:Acrylonitrile