title: Dietary Intake and Serum Level of Carotenoids in Lung Cancer Patients: A Case-Control Study.
abstract: The aim of this study was to compare the dietary intake and serum levels of some selected carotenoids of lung cancer patients with healthy subjects. Thirty-five lung cancer patients and 33 healthy people were enrolled into this case-control study. Daily intake of nutrients was estimated using a semiquantitative food frequency questionnaire and a 3-day 24-h food recall questionnaire. The concentration of serum beta-carotene and lycopene were analyzed using a high performance liquid chromatography method. Case and control groups did not differ by the means of age, gender, smoking habits, weight, body mass index, mean daily energy intake, mean daily fat intake, and the percentage of daily energy provided by fat to total daily energy intake. The beta-carotene and lycopene intake of the case subjects was 96% and 195% greater than that of the control subjects. Daily intake of fruits and vegetables in the cancer group was higher than the control group. However, the serum concentration of 118% beta-carotene and 60% lycopene were higher in the control group. Despite a higher daily dietary intake of beta-carotene and lycopene by lung cancer patients, serum beta-carotene and lycopene concentrations were significantly lower than the group without cancer.
authors.affiliation: a Department of Cellular and Molecular Nutrition , School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Somayeh
authors.initials: S
authors.lastname: Asbaghi
authors.forename: Ahmad
authors.initials: A
authors.lastname: Saedisomeolia
authors.forename: Mostafa
authors.initials: M
authors.lastname: Hosseini
authors.forename: Niyaz Mohammadzadeh
authors.initials: NM
authors.lastname: Honarvar
authors.forename: Adnan
authors.initials: A
authors.lastname: Khosravi
authors.forename: Eznollah
authors.initials: E
authors.lastname: Azargashb
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002338:Carotenoids / Q000008:administration & dosage / Q000097:blood*; D016022:Case-Control Studies; D002149:Energy Intake; D005260:Female; D005638:Fruit; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood*; D000077276:Lycopene; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D011795:Surveys and Questionnaires; D014675:Vegetables; D019207:beta Carotene / Q000008:administration & dosage / Q000097:blood*
chemical_list: D019207:beta Carotene; D002338:Carotenoids; D000077276:Lycopene