title: Syndromes that Link the Endocrine System and Genitourinary Tract.
abstract: The endocrine system and genitourinary tract unite in various syndromes. Genitourinary malignancies may cause paraneoplastic endocrine syndromes by secreting hormonal substances. These entities include Cushing`s syndrome, hypercalcemia, hyperglycemia, polycythemia, hypertension, and inappropriate ADH or HCG production. The most important syndromic scenarios that links these two systems are hereditary renal cancer syndromes with specific genotype/phenotype correlation. There are also some very rare entities in which endocrine and genitourinary systems are involved such as Carney complex, congenital adrenal hyperplasia and Beckwith-Wiedemann syndrome. We will review all the syndromes regarding manifestations present in endocrine and genitourinary organs.
authors.affiliation: Department of Pathology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey.
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Özlük
authors.forename: Işın
authors.initials: I
authors.lastname: Kılıçaslan
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics; D001706:Biopsy; D004701:Endocrine Gland Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D020022:Genetic Predisposition to Disease; D006801:Humans; D025202:Molecular Diagnostic Techniques; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D010641:Phenotype; D011237:Predictive Value of Tests; D011379:Prognosis; D014565:Urogenital Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor