title: Anti-N-methyl-d-aspartate receptor encephalitis: review of clinical presentation, diagnosis and treatment.
abstract: Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a form of encephalitis occurring primarily in women and associated with antibodies against NR1 or NR2 subunits of the NMDA receptor. As a potentially treatable differential for symptoms and signs seen in neurology and psychiatric clinics, clinicians practising across the lifespan should be aware of this form of encephalitis. Common clinical features include auditory and visual hallucinations, delusions, behavioural change (frequently with agitation), impaired consciousness, motor disturbance (ranging from dyskinesia to catatonia), seizures, and autonomic dysfunction. We present a review of the literature on the disorder, including its clinical presentation, differential diagnosis, epidemiology, treatment and prognosis.
authors.affiliation: Royal College of Surgeons in Ireland, Dublin, Ireland.
authors.forename: Helen
authors.initials: H
authors.lastname: Barry
authors.affiliation: Trinity College, Dublin.
authors.forename: Susan
authors.initials: S
authors.lastname: Byrne
authors.affiliation: Temple Street Children's University Hospital, Dublin.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Barrett
authors.affiliation: Royal College of Surgeons in Ireland, Dublin, Ireland.
authors.forename: Kieran C
authors.initials: KC
authors.lastname: Murphy
authors.affiliation: Royal College of Surgeons in Ireland, Dublin, Ireland.
authors.forename: David R
authors.initials: DR
authors.lastname: Cotter