title: Safety and esthetic outcomes of therapeutic mammoplasty using medial pedicle for early breast cancer.
abstract: BACKGROUND
  Although therapeutic mammoplasty (TM) was introduced for treatment of localized ductal carcinoma in situ and invasive breast carcinoma (stages I and II) in females with large breast size, the suitability of medial pedicle TM for treatment of breast tumors at different locations has not been established. The objective of this study was to assess the safety and esthetic outcome of medial pedicle TM for breast tumors at different locations.
  
  
  METHODS
  The study was conducted from February 2012 to July 2014. Consecutive patients with early breast carcinoma with medium- and large-sized breasts, with or without ptosis, who were offered medial pedicle TM were included in the study. Patients who were not candidates for breast-conserving surgery or those with tumors located along the medial pedicle were excluded. All patients received immediate postoperative adjuvant chemoradiotherapy.
  
  
  RESULTS
  Thirty patients with a mean age of 48.5 years received medial pedicle TM in the breast harboring the tumor or, additionally, the other breast (N=14). The tumors were in the upper (60.0%), lower (26.7%), and lateral (13.3%) quadrants. Minor complications occurred in five cases (5/30, 16.7%) in the ipsilateral and in two (2/14, 14.3%) contralateral breasts. No wound dehiscence or areolar necrosis was recorded. A total of 22 (73.3%) patients were scored as excellent cosmesis. After a median follow-up of 20 months, no locoregional recurrence or distant metastases were observed.
  
  
  CONCLUSIONS
  TM using a medial pedicle is a safe and appealing technique among women with tumors at different locations.
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Sameh
authors.initials: S
authors.lastname: Roshdy
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Osama
authors.initials: O
authors.lastname: Hussein
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Ashraf
authors.initials: A
authors.lastname: Khater
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zuhdy
authors.affiliation: Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
authors.forename: Hend A
authors.initials: HA
authors.lastname: El-Hadaad
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Omar
authors.initials: O
authors.lastname: Farouk
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Senbel
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Adel
authors.initials: A
authors.lastname: Fathi
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Emadeldeen
authors.initials: E
authors.lastname: Hamed
authors.affiliation: Department of Surgical Oncology, Mansoura Oncology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Adel
authors.initials: A
authors.lastname: Denewer
keywords: breast cancer; mastectomy; medial pedicle; therapeutic mammoplasty