title: Novel coumarin-based fluorescent probe for selective detection of Cu(II).
abstract: We report an efficient and convenient method for preparing nitro-3-carboxamide coumarin derivatives, proposed as novel fluorescent chemosensor, through microwave irradiation. This compound can be used as fluorescent probe for Cu(2+) with selectivity over other metal ions in aqueous solution. The fluorescence of 6-nitro-N-[2-(dimethylamino)ethyl]-2-oxo-2H-chromene-3-carboxamide(3) is the highest in the presence of Cu(2+), with stronger excitation at λ=320nm than for the other cations tested.
authors.affiliation: Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address: abekhradnia@gmail.com.
authors.forename: Ahmadreza
authors.initials: A
authors.lastname: Bekhradnia
authors.affiliation: Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Elham
authors.initials: E
authors.lastname: Domehri
authors.affiliation: Pharmaceutical Sciences Research Center, Department of Medicinal Chemistry, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Masome
authors.initials: M
authors.lastname: Khosravi
mesh_terms: D002413:Cations, Divalent / Q000032:analysis; D003300:Copper / Q000032:analysis*; D003374:Coumarins / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D008958:Models, Molecular; D013050:Spectrometry, Fluorescence
chemical_list: D002413:Cations, Divalent; D003374:Coumarins; D005456:Fluorescent Dyes; D003300:Copper; C030123:coumarin
keywords: Cation recognition; Coumarin derivatives; Fluorescent chemosensor