title: Muscle stem cells on the edge.
abstract: Release of muscle stem cells from quiescence involves the coordinated effort of transcription, mRNA stability, and translation. We focus this review on post-transcriptional regulation of muscle stem cells and highlight the impact of deregulated mRNA homeostasis on muscle aging and muscle disease pathogenesis.
authors.affiliation: Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, United States.
authors.forename: Jason D
authors.initials: JD
authors.lastname: Doles
authors.affiliation: Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309, United States. Electronic address: olwin@colorado.edu.
authors.forename: Bradley B
authors.initials: BB
authors.lastname: Olwin
mesh_terms: D002454:Cell Differentiation / Q000235:genetics; D049109:Cell Proliferation / Q000235:genetics; D016922:Cellular Senescence / Q000235:genetics; D006706:Homeostasis; D006801:Humans; D018482:Muscle, Skeletal / Q000166:cytology* / Q000254:growth & development; D020871:RNA Stability / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics; D013234:Stem Cells / Q000166:cytology* / Q000378:metabolism
chemical_list: D012333:RNA, Messenger