title: Diagnostic and treatment challenges in traumatic brain injury patients with severe neuropsychiatric symptoms: insights into psychiatric practice.
abstract: Traumatic brain injury (TBI) causes a variety of neuropsychiatric problems that pose diagnostic and treatment challenges for providers. In this report, we share our experience as a referral neuropsychiatry program to assist the general psychiatrist when adult TBI patients with psychiatric symptoms present for evaluation and treatment. We completed a retrospective study of patients with moderate-to-severe TBI and severe neuropsychiatric impairments. We collected information on demographics, nature of injury, symptomatology, diagnoses, and treatments. Data analysis indicates that mood stabilization was a key concern, often requiring aggressive pharmacological management. Cognitive dysfunction was a problem for the majority of patients, but was only medicated in a third, due to poor efficacy or behavioral side effects. The co-occurrence of multiple TBI-related symptoms and diagnoses in this patient cohort emphasizes the need for individualized psychopharmacological approaches and interventions.
authors.affiliation: The Neuropsychiatry Program at Sheppard Pratt, Sheppard Pratt Health System, Baltimore, MD, USA.
authors.forename: Margo D
authors.initials: MD
authors.lastname: Lauterbach
authors.affiliation: The Neuropsychiatry Program at Sheppard Pratt, Sheppard Pratt Health System, Baltimore, MD, USA.
authors.forename: Paula L
authors.initials: PL
authors.lastname: Notarangelo
authors.affiliation: Department of Emergency Medicine, The University of Tennessee College of Medicine Chattanooga, Chattanooga, TN, USA.
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Nichols
authors.affiliation: The Neuropsychiatry Program at Sheppard Pratt, Sheppard Pratt Health System, Baltimore, MD, USA.
authors.forename: Kristy S
authors.initials: KS
authors.lastname: Lane
authors.affiliation: The Neuropsychiatry Program at Sheppard Pratt, Sheppard Pratt Health System, Baltimore, MD, USA.
authors.forename: Vassilis E
authors.initials: VE
authors.lastname: Koliatsos
keywords: neurobehavioral; traumatic brain injury; treatment