title: A case of collagenous gastritis resembling nodular gastritis in endoscopic appearance.
abstract: A 25-year-old Japanese female was referred to our clinic for the investigation of moderate iron-deficiency anemia and epigastralgia. Endoscopic examination showed diffuse mucosal nodules in the gastric body resembling nodular gastritis, but this pattern was not observed in the antrum. Histology of the gastric biopsies taken from the gastric body showed mild atrophic mucosa with chronic active inflammation. Some of the biopsy specimens showed deposition of patchy, band-like subepithelial collagen. Four years later, the patient showed no clinical symptoms and signs. A follow-up endoscopic examination showed similar findings, which mimicked pseudopolyposis or a cobblestone-like appearance. The biopsy specimens from the depressed mucosa between the nodules revealed a thickened subepithelial collagen band with no improvement, which led to a diagnosis of collagenous gastritis. Treatment with oral administration of proton-pump inhibitors and histamine-2-receptor antagonists had proved ineffective. To make a correct diagnosis of collagenous gastritis, we should determine the characteristic endoscopic findings and take biopsies from the depressed mucosa between the nodules.
authors.affiliation: Teramoto Memorial Nishitenma Clinic, AS Building 3F, 3-13-20 Nishitenma, Kita-ku, Osaka, 530-0043, Japan. jun_vader_tanabe@ybb.ne.jp.
authors.forename: Jun
authors.initials: J
authors.lastname: Tanabe
authors.affiliation: Sankei Health Insurance Society Clinic, Osaka, Japan.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Yasumaru
authors.affiliation: Department of Pathology, Osaka Police Hospital, Osaka, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Tsujimoto
authors.affiliation: Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Iijima
authors.affiliation: Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hiyama
authors.affiliation: Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Nishio
authors.affiliation: Department of Gastroenterology, Teramoto Memorial Hospital, Kawachinagano, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Sasayama
authors.affiliation: Endoscopy Center, Osaka Police Hospital, Osaka, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Kawai
authors.affiliation: Department of Internal Medicine, Osaka Police Hospital, Osaka, Japan.
authors.forename: Masahide
authors.initials: M
authors.lastname: Oshita
authors.affiliation: Department of Gastroenterology, Takarazuka Municipal Hospital, Takarazuka, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Abe
authors.affiliation: Hankyu Corp. Clinic, Nishinomiya, Japan.
authors.forename: Sunao
authors.initials: S
authors.lastname: Kawano
keywords: Collagen band; Collagenous gastritis; Nodular gastritis; Pseudopolyposis