title: New Laurene-type Sesquiterpene from Bornean Laurencia nangii.
abstract: We report the chemical composition of a population of Bornean Laurencia nangii Masuda. A new compound, neolaurene (1), along with five known metabolites, neolaurallene (2), 2,10-dibromo-3-chloro-α-chamigrene (3), deoxyprepacifenol (4), cycloelatanene B (5) and intricatetraol (6), were isolated and their chemical structures elucidated based on spectroscopic data. In addition, their cytotoxicity and antibacterial activity were evaluated.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kamada
authors.forename: Charles Santhanaraju
authors.initials: CS
authors.lastname: Vairappan
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D044722:Laurencia / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000461:Rhodophyta / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D012717:Sesquiterpenes