title: Acute rhabdomiolisys in healthy woman.
abstract: Our patient is a 42-year-old woman with muscle paralysis, muscle weakness, and fever. On admission, a neurologic examination showed proximal and distal weakness in the leg. Serum creatine phosphokinase and serum myoglobin level were markedly increased (5600 UI/L and 5197 UI/L, respectively). There was no sign of renal failure. Nerve conduction study was negative. Serologic studies for virus titers showed the antibody immunoglobulin M cytomegalovirus. Muscle weakness and its paralysis, fever, and serum creatine kinase level gradually improved after the administration of methylprednisolone intravenous. Cytomegalovirus infection was thought to have played a central role in this case, leading to an acute but reversible peripheral muscle paralysis.
authors.affiliation: Second University of Naples, Naples, Italy; Hospital F. Veneziale, Isernia, Italy.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Ciarambino
authors.affiliation: Second University of Naples, Naples, Italy; Hospital F. Veneziale, Isernia, Italy.
authors.forename: Luigi Elio
authors.initials: LE
authors.lastname: Adinolfi
authors.affiliation: Second University of Naples, Naples, Italy; Hospital F. Veneziale, Isernia, Italy. Electronic address: Mauro.giordano@unina2.it.
authors.forename: Mauro
authors.initials: M
authors.lastname: Giordano
mesh_terms: D000208:Acute Disease; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D012206:Rhabdomyolysis / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone