title: Tube Polypropylene: A Neglected Critical Parameter for Protein Adsorption During Biospecimen Storage.
abstract: This biospecimen research case study illustrates the importance of a neglected pre-analytical factor, the polypropylene type of storage tubes. We measured amyloid β1-42 peptide and showed that a non-irradiated, homopolymer type of polypropylene has the lowest adsorption properties.
authors.affiliation: Integrated Biobank of Luxembourg (IBBL) , Luxembourg, Luxembourg .
authors.forename: Olga A
authors.initials: OA
authors.lastname: Kofanova
authors.affiliation: Integrated Biobank of Luxembourg (IBBL) , Luxembourg, Luxembourg .
authors.forename: Kathleen
authors.initials: K
authors.lastname: Mommaerts
authors.affiliation: Integrated Biobank of Luxembourg (IBBL) , Luxembourg, Luxembourg .
authors.forename: Fay
authors.initials: F
authors.lastname: Betsou
mesh_terms: D000327:Adsorption; D000544:Alzheimer Disease / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D016229:Amyloid beta-Peptides / Q000134:cerebrospinal fluid* / Q000737:chemistry; D018070:Biological Specimen Banks; D015415:Biomarkers / Q000737:chemistry; D003951:Diagnostic Errors; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D011108:Polymers / Q000737:chemistry; D011126:Polypropylenes / Q000737:chemistry*; D013048:Specimen Handling / Q000379:methods*; D013696:Temperature
chemical_list: D016229:Amyloid beta-Peptides; D015415:Biomarkers; D011108:Polymers; D011126:Polypropylenes