title: Effects of High Hydrostatic Pressure on Microbial Cell Membranes: Structural and Functional Perspectives.
abstract: Biological processes associated with dynamic structural features of membranes are highly sensitive to changes in hydrostatic pressure and temperature. Marine organisms potentially experience a broad range of pressure and temperature fluctuations. Hence, they have specialized cell membranes to perform membrane protein functions under various environmental conditions. Although the effects of high pressure on artificial lipid bilayers have been investigated in detail, little is known about how high pressure affects the structure of natural cell membranes and how organisms cope with pressure alterations. This review focused on the recent advances in research on the effects of high pressure on microbial membranes, particularly on the use of time-resolved fluorescence anisotropy measurement to determine membrane dynamics in deep-sea piezophiles.
authors.affiliation: Department of Chemistry and Biological Science, College of Science and Engineering, Aoyama Gakuin University, 5-10-1 Fuchinobe, Chuo-ku, Sagamihara, 252-5258, Japan, abef@chem.aoyama.ac.jp.
authors.forename: Fumiyoshi
authors.initials: F
authors.lastname: Abe
mesh_terms: D001419:Bacteria / Q000737:chemistry*; D002462:Cell Membrane / Q000737:chemistry; D005231:Fatty Acids, Unsaturated / Q000737:chemistry; D006874:Hydrostatic Pressure; D012441:Saccharomyces cerevisiae / Q000737:chemistry*
chemical_list: D005231:Fatty Acids, Unsaturated