title: [The clinical use of cryopreserved human skin allografts for transplantation].
abstract: BACKGROUND
  The biological recovery of human skin allografts is the gold standard for preservation in Skin Banks. However, there is no worldwide consensus about specific allocation criteria for preserved human skin allografts with living cells. A report is presented on the results of 5 years of experience of using human skin allografts in burned patient in the Skin and Tissue Bank at the "Instituto Nacional de Rehabilitacion"
  
  
  METHODS
  The human skin allografts were obtained from multi-organ donors. processed and preserved at -80 °C for 12 months. Allocation criteria were performed according to blood type match, clinical history, and burned body surface.
  
  
  RESULTS
  Up to now, the Skin and Tissue Bank at 'Instituto Nacional de Rehabilitacion" has processed and recovered 125,000 cm(2) of human skin allografts. It has performed 34 surgical implants on 21 burned patients. The average of burn body surface was 59.2%. More than two-thirds (67.7%) of recipients of skin allografts were matched of the same to type blood of the donor, and 66.6% survived after 126 days hospital stay.
  
  
  CONCLUSIONS
  It is proposed to consider recipient's blood group as allocation criteria to assign tissue; and use human skin allografts on patiens affected with burns over 30% of body surface (according the "rule of the 9").
authors.affiliation: Banco de Piel y Tejidos, Instituto Nacional de Rehabilitación, Secretaría de Salud, México, D.F., México. Electronic address: fcomartinez@inr.gob.mx.
authors.forename: Francisco
authors.initials: F
authors.lastname: Martínez-Flores
authors.affiliation: Banco de Piel y Tejidos, Instituto Nacional de Rehabilitación, Secretaría de Salud, México, D.F., México.
authors.forename: María
authors.initials: M
authors.lastname: Chacón-Gómez
authors.affiliation: Banco de Piel y Tejidos, Instituto Nacional de Rehabilitación, Secretaría de Salud, México, D.F., México.
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Madinaveitia-Villanueva
authors.affiliation: Banco de Piel y Tejidos, Instituto Nacional de Rehabilitación, Secretaría de Salud, México, D.F., México.
authors.forename: Araceli
authors.initials: A
authors.lastname: Barrera-Lopez
authors.affiliation: Laboratorio de Neuroinmunoendocrinología, Instituto Nacional de Neurología y Neurocirugía «Manuel Velasco Suarez», Secretaría de Salud, México, D.F., México.
authors.forename: Lucinda
authors.initials: L
authors.lastname: Aguirre-Cruz
authors.affiliation: Coordinación de Donación de Órganos y Tejidos, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D.F., México.
authors.forename: Walter
authors.initials: W
authors.lastname: Querevalu-Murillo
mesh_terms: D000293:Adolescent; D000328:Adult; D064591:Allografts; D002056:Burns / Q000382:microbiology / Q000401:mortality / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D015925:Cryopreservation; D005260:Female; D006085:Graft Survival; D006648:Histocompatibility; D006801:Humans; D007223:Infant; D007902:Length of Stay; D008297:Male; D008800:Mexico; D008875:Middle Aged; D009926:Organ Preservation; D012867:Skin; D012874:Skin Diseases, Infectious / Q000453:epidemiology / Q000382:microbiology; D016038:Skin Transplantation / Q000379:methods* / Q000706:statistics & numerical data; D014015:Tissue Banks; D014019:Tissue Donors; D020858:Tissue and Organ Harvesting; D016896:Treatment Outcome; D014946:Wound Infection / Q000453:epidemiology / Q000382:microbiology; D055815:Young Adult
keywords: Aloinjertos de piel; Banco de tejidos; Quemaduras; Recuperación biológica; Tissue bank; biological recovery; burns; skin allografts