title: Lymphatic filariasis baseline survey in two sentinel sites of Ogun state, Nigeria.
abstract: BACKGROUND
  In preparation for Mass Drug Administration by National Lymphatic Filariasis Elimination Programme, a baseline epidemiological investigation on lymphatic filariasis (LF) was conducted in two sentinel sites of Ogun State, Nigeria. The study was carried out in Ado-Odo Ota and Abeokuta South Local Government Areas (LGAs) to determine LF prevalence, microfilarial density and the abundance of Wucheraria bancrofti in the mosquito vectors.
  
  
  METHODS
  Microscopic examination of thick blood smears of 299 and 288 participants from Ado-Odo Ota and Abeokuta South LGAs was conducted. Visual observations of clinical manifestations of chronic infection and questionnaire administration were also conducted. Indoor resting mosquitoes were collected using the pyrethrum spray technique and CDC light traps and mosquitoes were dissected for filarial larvae.
  
  
  RESULTS
  Microfilaria prevalences were 4.0% and 2.4% in Ado-odo Ota and Abeokuta South LGAs. The microflarial density (mfd) was 30.6mf/ml and 23.9 mf/ml in the same areas. No clinical manifestations of the infection were found at both sites. Knowledge of LF by inhabitants was very low in the two areas. Anopheles gambiae s.l and Culex species mosquitoes were collected but none was found positive for stage L3 infective larvae.
  
  
  CONCLUSIONS
  Mass awareness campaigns on the goal of mass drug administration, cause of LF, mode of transmission, the relationship between infection and clinical signs/symptoms is advocated so as to increase acceptance and support of the control programme by the community.
authors.affiliation: Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
authors.forename: Patricia Nkem
authors.initials: PN
authors.lastname: Okorie
authors.affiliation: Ministry of Health, Nigeria.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Davies
authors.affiliation: Ministry of Health, Nigeria.
authors.forename: Olushola Omoniyi
authors.initials: OO
authors.lastname: Ogunmola
authors.affiliation: Department of Medical Microbiology and Parasitology, Ladoke Akintola University of Technology, Osogbo, Osun State, Nigeria.
authors.forename: Olusola
authors.initials: O
authors.lastname: Ojurongbe
authors.affiliation: Ministry of Health, Nigeria.
authors.forename: Yisa
authors.initials: Y
authors.lastname: Saka
authors.affiliation: Ministry of Health, Nigeria.
authors.forename: Bridget
authors.initials: B
authors.lastname: Okoeguale
authors.affiliation: Department of Zoology, Federal University Lafia, Nasarawa State, Nigeria.
authors.forename: Ekanem Ikpi
authors.initials: EI
authors.lastname: Braide
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002648:Child; D002675:Child, Preschool; D009033:Culicidae / Q000469:parasitology*; D004605:Elephantiasis, Filarial / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology*; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D011795:Surveys and Questionnaires; D014958:Wuchereria bancrofti / Q000302:isolation & purification*; D055815:Young Adult
keywords: Anopheles gambiae s.l; Culex species; Lymphatic filariasis; Mosquitoes; Nigeria; Wucheraria bancrofti