title: The Biology of Vibrio vulnificus.
abstract: Vibrio vulnificus, carrying a 50% fatality rate, is the most deadly of the foodborne pathogens. It occurs in estuarine and coastal waters and it is found in especially high numbers in oysters and other molluscan shellfish. The biology of V. vulnificus, including its ecology, pathogenesis, and molecular genetics, has been described in numerous reviews. This article provides a brief summary of some of the key aspects of this important human pathogen, including information on biotypes and genotypes, virulence factors, risk factor requirements and the role of iron in disease, association with oysters, geographic distribution, importance of salinity and water temperature, increasing incidence associated with global warming. This article includes some of our findings as presented at the "Vibrios in the Environment 2010" conference held in Biloxi, MS.
authors.affiliation: Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC 28223.
authors.forename: James D
authors.initials: JD
authors.lastname: Oliver
mesh_terms: D000818:Animals; D016667:Bacterial Capsules / Q000276:immunology / Q000473:pathology; D005517:Foodborne Diseases / Q000382:microbiology*; D057232:Global Warming; D006801:Humans; D007501:Iron / Q000378:metabolism; D010125:Ostreidae / Q000382:microbiology*; D012307:Risk Factors; D054712:Salinity; D012623:Seawater / Q000382:microbiology; D018805:Sepsis / Q000382:microbiology / Q000473:pathology; D012758:Shellfish / Q000382:microbiology*; D013696:Temperature; D014735:Vibrio Infections / Q000382:microbiology* / Q000473:pathology; D041261:Vibrio vulnificus / Q000145:classification / Q000472:pathogenicity*; D037521:Virulence Factors / Q000378:metabolism; D014871:Water Microbiology
chemical_list: D037521:Virulence Factors; D007501:Iron