title: Four-year survival of a patient with malignant fibrous histiocytoma of the liver treated with surgery and chemotherapy.
abstract: Malignant fibrous histiocytoma of the liver is an extremely rare tumor. A 43-year-old woman was admitted with an enlargement of the abdomen and a feeling of general fatigue. A clinical examination revealed a right liver giant cystic tumor (18.5 × 22 cm). The cystic tumor, which contained a solid component, occupied almost the entire right lobe of the liver, and a solid S4 tumor was also observed. A blood examination revealed severe anemia and mild liver dysfunction. During hospitalization intratumor bleeding occurred. A right lobectomy of the liver and lymph node dissection was performed after transcatheter arterial embolization. Histopathologically, the tumor was diagnosed as a primary storiform-pleomorphic-type malignant fibrous histiocytoma of the liver. One year after the radical operation, the patient developed recurrences in other organs. She received 17 cycles of chemotherapy with etoposide, ifosfamide, and cisplatin. The recurrent tumors decreased in size, but new recurrences in other organs occurred. The patient died of respiratory failure 4 years and 2 months after the initial operation.
authors.affiliation: Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan. shioya@nms.ac.jp.|Department of Surgery, Omiya Medical Association Hospital, 2-125-16 Miyahara-cho, Kita-ku, Saitama, Saitama, 331-8689, Japan. shioya@nms.ac.jp.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shioya
authors.affiliation: Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Yuzuriha
authors.affiliation: Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Maejima
authors.affiliation: Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Mizutani
authors.affiliation: Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.|Department of Surgery, Omiya Medical Association Hospital, 2-125-16 Miyahara-cho, Kita-ku, Saitama, Saitama, 331-8689, Japan.
authors.forename: Kotaro
authors.initials: K
authors.lastname: Nambu
authors.affiliation: Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.
authors.forename: Arichika
authors.initials: A
authors.lastname: Hoshino
authors.affiliation: Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.|Department of Surgery, Omiya Medical Association Hospital, 2-125-16 Miyahara-cho, Kita-ku, Saitama, Saitama, 331-8689, Japan.
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Shibuya
authors.affiliation: Institute of Gastroenterology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Tokunaga
authors.affiliation: Department of Pathology, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.
authors.forename: Koshi
authors.initials: K
authors.lastname: Matsumoto
authors.affiliation: Surgery for Organ Function and Biological Regulation, Nippon Medical School Graduate School of Medicine, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tajiri
keywords: Chemotherapy; Liver; Malignant fibrous histiocytoma; Sarcoma; Surgery