title: Drug-induced myopathy in a patient with pulmonary tuberculosis.
abstract: A 26-year-old man, who had started treatment for pulmonary tuberculosis, developed polyarthralgia, generalised myalgia, weakness, and elevated uric acid and creatine kinase levels. His polyarthralgia improved on cessation of pyrazinamide, but the improvement in his myalgia and creatine kinase was delayed. Drug-induced myopathy was considered as there were no clear alternative explanations.
authors.affiliation: Department of Infectious Diseases, Nottingham University Hospitals City Campus, Nottingham, UK.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Shah
authors.affiliation: Department of Infectious Diseases, Nottingham University Hospitals City Campus, Nottingham, UK.
authors.forename: Pradhib
authors.initials: P
authors.lastname: Venkatesan
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D018771:Arthralgia / Q000139:chemically induced / Q000188:drug therapy; D003402:Creatine Kinase / Q000378:metabolism; D006801:Humans; D008297:Male; D018908:Muscle Weakness / Q000139:chemically induced / Q000188:drug therapy; D009135:Muscular Diseases / Q000139:chemically induced* / Q000378:metabolism; D063806:Myalgia / Q000139:chemically induced / Q000188:drug therapy; D011718:Pyrazinamide / Q000009:adverse effects* / Q000627:therapeutic use; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*; D014527:Uric Acid / Q000378:metabolism
chemical_list: D000995:Antitubercular Agents; D014527:Uric Acid; D011718:Pyrazinamide; D003402:Creatine Kinase