title: [Management of overactive bladder in women].
abstract: Overactive bladder (OAB) is defined as urgency, with or without urge incontinence, usually with frequency and nocturia. OAB has been reported in 9 to 43% of female patients. It is usually idiopathic. The diagnosis is clinical but an initial work-up may be needed to exclude an underlying cause (bladder tumor, stone, cystitis, neurological disorder…) using urinary tract ultrasound, urine culture or cystoscopy. The initial assessment may also include a frequency-volume chart and urodynamics. Behavioral therapy is the first line treatment. In case of failure, antimuscarinics are recommended. Nowadays, three treatment options are available for OAB refractory to antimuscarinics: sacral neuromodulation, peripheral tibial nerve stimulation and intra-detrusor injections of botulinum toxin. Surgical procedures such as augmentation cystoplasty are very rarely required.
authors.affiliation: Service d'urologie, hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35000 Rennes, France. Electronic address: peyronnetbenoit@hotmail.fr.
authors.forename: B
authors.initials: B
authors.lastname: Peyronnet
authors.affiliation: Service de médecine physique et rééducation, CHU de Rennes, 35000 Rennes, France.
authors.forename: H
authors.initials: H
authors.lastname: Rigole
authors.affiliation: Service de médecine physique et rééducation, CHU de Rennes, 35000 Rennes, France.
authors.forename: M
authors.initials: M
authors.lastname: Damphousse
authors.affiliation: Service d'urologie, hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35000 Rennes, France.
authors.forename: A
authors.initials: A
authors.lastname: Manunta
mesh_terms: D000283:Administration, Intravesical; D001905:Botulinum Toxins / Q000627:therapeutic use; D018680:Cholinergic Antagonists; D003558:Cystoscopy; D003937:Diagnosis, Differential; D004599:Electric Stimulation Therapy; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D009498:Neurotoxins / Q000627:therapeutic use; D014463:Ultrasonography; D053201:Urinary Bladder, Overactive / Q000175:diagnosis / Q000628:therapy*; D014551:Urinary Tract / Q000000981:diagnostic imaging; D014552:Urinary Tract Infections / Q000175:diagnosis; D014563:Urodynamics
chemical_list: D018680:Cholinergic Antagonists; D009498:Neurotoxins; D001905:Botulinum Toxins