title: Surgical experience of primary salivary gland tumors of lung: A case series.
abstract: BACKGROUND
  Primary salivary gland type tumors of lung (PSGTTL) are rare intra-thoracic malignant neoplasm. Their description in literature is largely limited to a few case series/case reports. We herewith present our surgical experience of and review its clinical presentation, management options and survival outcomes.
  
  
  METHODS
  This retrospective analysis of prospectively maintained computerized data-base of patients was conducted in a tertiary teaching oncology centre in North India. The case records of all the patients who underwent surgery for PSGTTL were reviewed. Details concerning the clinical presentation, preoperative therapy, operative procedure, histopathological examination, postoperative complications and outcome were retrieved from the case records.
  
  
  RESULTS
  There were seven patients who underwent surgery for PSGTTL during the period from January 2012 to December 2014. Hemoptysis (n = 6, 85.7%) and dyspnoea (n = 6, 85.7%) were common presenting clinical features. Fiber-optic bronchoscopy revealed endobronchial growth in all patients - five patients had growth in left main bronchus while one each had growth in right main bronchus and right intermediate bronchus. Biopsy confirmed adenoid cystic carcinoma in 4 (57.1%) and muco-epidermoid carcinoma in 3 (42.9%) patients. All but one had R'0' resection - pneumonectomy in five and bilobectomy in one patient; one patient was found to be unresectable in view of dense adhesions between lung and heart. Median pathological tumor size was 3.5 cm; none of the patient was found to have metastatic spread to lymph nodes. Overall, six patients are alive after a median follow up of 5 months (range 1-30).
  
  
  CONCLUSIONS
  Radical surgery to achieve R'0' resection is the main stay of treatment of PSGTTL to achieve prolonged survival.
authors.affiliation: Department of Surgical Oncology, Dr BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Durgatosh
authors.initials: D
authors.lastname: Pandey
authors.affiliation: Department of Surgical Oncology, Dr BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India; Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, New Delhi, India. Electronic address: dr.pankajgarg@gmail.com.
authors.forename: Pankaj Kumar
authors.initials: PK
authors.lastname: Garg
authors.affiliation: Department of Surgical Oncology, Dr BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Jakhetiya
authors.affiliation: Department of Radiation Oncology, Dr BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Rambha
authors.initials: R
authors.lastname: Pandey
authors.affiliation: Department of Surgical Oncology, Dr BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Bhoriwal
authors.affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Devajit
authors.initials: D
authors.lastname: Nath
authors.affiliation: Department of Surgical Oncology, Dr BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Kumar
mesh_terms: D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology* / Q000601:surgery; D018277:Carcinoma, Mucoepidermoid / Q000473:pathology* / Q000601:surgery; D004417:Dyspnea / Q000209:etiology; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D035583:Rare Diseases; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000601:surgery
keywords: Adenoid cystic carcinoma; Bronchoscopy; Lung neoplasms; Lung surgery; Mucoepidermoid carcinoma; Pneumonectomy; Salivary gland neoplasms