title: Early severe preeclampsia with marked platelet dysfunction in association with essential thrombocytemia: case report and discussion.
abstract: Essential thrombocytemia--a classic myeloproliferative neoplasm characterized by persistent thrombocytosis--may associate both thrombotic and hemorrhagic events, as well as platelet dysfunction. Of all myeloproliferative neoplasms, essential thrombocytemia is more likely to be associated with pregnancy, because of a higher comparative incidence in younger patients. This association significantly increases the risk of pregnancy loss and of various pregnancy complications. We present a case of early severe preeclampsia with a critical and unusual evolution and life-threatening complications.
authors.affiliation: aHematology Department, University Emergency Hospital Bucharest bObstetrics-Gynecology Department, Elias University Emergency Hospital cHematology Department, Colentina Hospital, Bucharest, Romania.
authors.forename: Minodora
authors.initials: M
authors.lastname: Onisai
authors.forename: Irina
authors.initials: I
authors.lastname: Voican
authors.forename: Mihai
authors.initials: M
authors.lastname: Ciorascu
authors.forename: Viola
authors.initials: V
authors.lastname: Popov
authors.forename: Horia
authors.initials: H
authors.lastname: Bumbea
authors.forename: Mihaela
authors.initials: M
authors.lastname: Gaman
authors.forename: Alexandru
authors.initials: A
authors.lastname: Filipescu
authors.forename: Radu
authors.initials: R
authors.lastname: Vladareanu
authors.forename: Ana-Maria
authors.initials: AM
authors.lastname: Vladareanu
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000166:cytology / Q000378:metabolism*; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000209:etiology* / Q000503:physiopathology; D011247:Pregnancy; D013920:Thrombocythemia, Essential / Q000150:complications*