title: Meta-analysis for dorsally displaced distal radius fracture fixation: volar locking plate versus percutaneous Kirschner wires.
abstract: BACKGROUND
  Dorsally displaced distal radius fractures (DDDRF) are frequent injuries in clinical practice. Traditional percutaneous Kirschner wires (K-wire) and open reduction with volar locking plate (VLP) are the two most common surgical fixation techniques used to manage DDDRF. However, there is no current consensual evidence to guide the selection of one technique over the other. Therefore, we undertook a systematic search and meta-analysis to compare clinical outcomes and complications of these two treatment approaches for DDDRF.
  
  
  METHODS
  The following electronic databases were searched by two independent reviewers, up to April 2015: PubMed, ScienceDirect and Wiley Online Library. High-quality randomized controlled trials (RCTs) comparing VLP and percutaneous K-wire fixation for DDDRF were identified. Pooled mean differences were calculated for the following continuous outcome variables: disabilities of the arm, shoulder and hand (DASH) score, grip strength and wrist range of motion. Pooled odds ratios were calculated for rates of total postoperative complications, including superficial infection, deep infection, complex regional pain syndrome (CRPS), carpal tunnel syndrome (CTS), neurological injury, tendon rupture, tenosynovitis, loss of reduction and additional surgery to remove hardware. The meta-analysis was completed using RevMan 5.3 software.
  
  
  RESULTS
  Seven RCTs, with a total of 875 patients, were included in our meta-analysis. Open reduction internal fixation (ORIF) with VLP fixation provided statistically lower DASH scores, reduced the incidence of total postoperative complications and specifically lowered the rate of superficial infection, when compared, over a 1-year follow-up, to percutaneous K-wire fixation. VLP fixation also provided significantly better grip strength and range of wrist flexion and supination in the early 6-month postoperative period, compared with percutaneous K-wire fixation.
  
  
  CONCLUSIONS
  ORIF with VLP fixation provided lower DASH scores and reduced total postoperative complications, most specifically lowering the risk for postoperative superficial infection compared to K-wire fixation over a 1-year follow-up period. However, superficial pin track infections do not cause clinical debility in the vast majority of cases. Thus, the claim of reduced superficial infection rate may not be clinically important. The only reasonable conclusion that can be drawn is that at present, there is insufficient data even on our meta-analysis to help the clinician make an informed choice.
authors.affiliation: Department of Orthopedics Institute, Tianjin Medical University, Tianjin, 300070, People's Republic of China. zongshuangle@163.com.|Department of Orthopedics Institute, The Second Hospital of Tangshan, Tangshan, 063000, Hebei Province, People's Republic of China. zongshuangle@163.com.
authors.forename: Shuang-Le
authors.initials: SL
authors.lastname: Zong
authors.affiliation: Department of Orthopedics Institute, Tianjin Medical University, Tianjin, 300070, People's Republic of China. kanshilian@aliyun.com.
authors.forename: Shi-Lian
authors.initials: SL
authors.lastname: Kan
authors.affiliation: Department of Orthopedics Institute, The Second Hospital of Tangshan, Tangshan, 063000, Hebei Province, People's Republic of China. 798777276@qq.com.
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Su
authors.affiliation: Department of Orthopedics Institute, The Second Hospital of Tangshan, Tangshan, 063000, Hebei Province, People's Republic of China. 275449940@qq.com.
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
mesh_terms: D001860:Bone Plates / Q000639:trends; D001864:Bone Wires / Q000639:trends; D005593:Fracture Fixation, Internal / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D006801:Humans; D011885:Radius Fractures / Q000175:diagnosis / Q000601:surgery*; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D016059:Range of Motion, Articular / Q000502:physiology; D016896:Treatment Outcome