title: Clinical and Neurologic Manifestation of Minimal Hepatic Encephalopathy and Overt Hepatic Encephalopathy.
abstract: Hepatic encephalopathy (HE) shows a wide spectrum of neuropsychiatric manifestations. A combined effort with neuropsychological and psychometric evaluation has to be performed to recognize the syndrome, whereas minimal HE (MHE) is largely under-recognized. Subtle symptoms of MHE can only be diagnosed through specialized neuropsychiatric testing. Early diagnosis and treatment may drastically improve the quality of life for many cirrhotic patients. Further research to gain better insight into the pathophysiology and diagnostic accuracy of HE will help determine future management strategies.
authors.affiliation: Department of Medicine, Columbia University College of Physicians and Surgeons, 622 West 168 Street, New York, NY 10032, USA; Department of Medicine, King's County Hospital Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
authors.forename: P Patrick
authors.initials: PP
authors.lastname: Basu
authors.affiliation: Department of Medicine, James J. Peters VA Medical Center, Icahn School of Medicine at Mount Sinai, 130 West Kingsbridge Road, New York, NY 10468, USA. Electronic address: nirajjames@gmail.com.
authors.forename: Niraj James
authors.initials: NJ
authors.lastname: Shah
mesh_terms: D000818:Animals; D001334:Automobile Driving / Q000523:psychology*; D003072:Cognition Disorders / Q000209:etiology; D006501:Hepatic Encephalopathy / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D009483:Neuropsychological Tests; D012720:Severity of Illness Index; D020919:Sleep Disorders, Intrinsic / Q000209:etiology
keywords: MHE; Minimal hepatic encephalopathy; Neurologic manifestation; OHE; Overt hepatic encephalopathy