title: [A Meta analysis of family risk factors for attention deficit hyperactivity disorder].
abstract: OBJECTIVE
  To investigate the risk factors for attention deficit hyperactivity disorder (ADHD) and to provide a basis for future prevention and treatment of this disease.
  
  
  METHODS
  Following a systematic search for case-control studies on the risk factors for ADHD in China between 2000 and 2014, relevant family risk factors were extracted accordingly. The quality of selected studies was evaluated according to the NOS scale. A Meta analysis on the selected studies was conducted using Stata 12.0 software.
  
  
  RESULTS
  A total of 16 studies were selected, involving 2 167 children with ADHD and 2 148 normal controls. Results of Meta analysis showed that good parenting (OR=0.32, 95% CI: 0.26-0.40), nuclear family (OR=0.56, 95% CI: 0.41-0.76), high education level of father (OR=0.56, 95% CI: 0.41-0.76), high education level of mother (OR=0.65, 95% CI: 0.47-0.89), and extroversion of mother (OR=0.33, 95% CI: 0.18-0.61) are favorable factors for ADHD. Poor parental relationship (OR=1.90, 95% CI: 1.17-3.06) and family history of ADHD (OR=5.86, 95% CI: 3.67-9.35) are risk factors for ADHD.
  
  
  CONCLUSIONS
  Good parenting, nuclear family, high education level of parents, and mother with extroversion are protective factors for ADHD, whereas poor parental relationship and family history of ADHD are associated with an increased risk for ADHD.
authors.affiliation: Graduate School of Xuzhou Medical College, Xuzhou, Jiangsu 221000, China. gxsunny@hotmail.com.
authors.forename: Ya-Feng
authors.initials: YF
authors.lastname: Zhang
authors.forename: Gui-Xiang
authors.initials: GX
authors.lastname: Sun
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000209:etiology* / Q000235:genetics; D005190:Family; D006801:Humans; D012307:Risk Factors