title: Acaricidal activity of extracts fromLigularia virgaureaagainst theSarcoptes scabieimitein vitro.
abstract: The aim of the present study was to investigate the acaricidal activity ofLigularia virgaurea. An extract was prepared by refluxing with ethanol and steam distillation, and its toxic effect was testedin vitroagainstSarcoptes scabiei. The data from the toxicity tests were analyzed using a complementary log-log (CLL) model. The ethanol extract exhibited strong acaricidal activity against these mites; at a concentration of 2 g/ml it killed allS. scabieiwithin 2 h and at 1 g/ml it killed allS. scabieiwithin 6 h. Similarly, 2, 1, 0.5 and 0.25 g/ml concentrations of the extract had strong toxicity againstS. scabiei, with median lethal time (LT50) values of 0.716, 1.741, 2.968 and 4.838 h, respectively. The median lethal concentration (LC50) values were 1.388, 0.624, 0.310 and 0.213 g/ml forScabiesmite in 1, 2, 4 and 6 h, respectively. The results indicate that theL. virgaureaextract has strong acaricidal activity and may be exploited as a novel treatment for the effective control of acariasis in animals.
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Biao
authors.initials: B
authors.lastname: Luo
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China ; Qiandongnan Prefectural Center for Animal Disease Control and Prevention, Kaili, Guizhou 556000, P.R. China.
authors.forename: Fei
authors.initials: F
authors.lastname: Liao
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Yanchun
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Ganzi Institute of Animal Husbandary, Kangding, Sichuan 626000, P.R. China.
authors.forename: X I
authors.initials: XI
authors.lastname: Liu
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Yajun
authors.initials: Y
authors.lastname: He
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Wu
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Hui
authors.initials: H
authors.lastname: Tan
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Lijuan
authors.initials: L
authors.lastname: Luo
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Yancheng
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Mo
authors.affiliation: Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, P.R. China.
authors.forename: Junliang
authors.initials: J
authors.lastname: Deng
authors.affiliation: Key Laboratory of Resource Biology and Biotechnology in Western China, School of Life Science, Northwest University, Xi'an, Shaanxi 710069, P.R. China.
authors.forename: Yahui
authors.initials: Y
authors.lastname: Wei
keywords: Ligularia virgaurea; Sarcoptes scabiei; acaricidal activity; toxic effect