title: Comparison of a New High-Frequency Electric Welding System for Intestinal Closure with Hand-Sewn In Vivo Pig Model.
abstract: BACKGROUND
  Various surgical small intestinal anastomosis methods are in current use, but improvements are always desired. Thus, we compared the feasibility, effectiveness, and safety of a new high-frequency electric welding (HFEW) system for sealing the small bowel versus a hand-sewn in vivo pig model.
  
  
  METHODS
  The 96 bowel segments of three pigs were randomized to be sutured either by the HFEW-300 PATONMED device (E.O. Paton Electric Welding Institute of the National Academy of Sciences of Ukraine, Kiev, Ukraine) or hand-sewn, and mucosa-to-mucosa fusions were subjected in vivo testing in the pigs. Bursting pressures, suture time, thermal damage, and the temperature of sealed ends were measured.
  
  
  RESULTS
  Segments that had been treated with a hand-sutured ligature or double-sealed with HFEW were compared. Burst pressure was significantly higher in the hand-sutured group than in the HFEW group (136.2 mm Hg versus 75.8 mm Hg, P<.01). All 48 pig small bowels closed by the HFEW-300 generator showed a success rate of 100.0%. The closing time in the HFEW group was significantly shorter (P<.01). The pathological changes of the closed ends were mainly presented as acute thermal- and pressure-induced injuries.
  
  
  CONCLUSIONS
  Outcomes of the current in vivo study suggest that HFEW is an effective and safe method for ligation of the small bowel in pigs.
authors.affiliation: 1 Department of General Surgery, Zhujiang Hospital, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Shuai
authors.initials: S
authors.lastname: Han
authors.affiliation: 1 Department of General Surgery, Zhujiang Hospital, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Zhai
authors.initials: Z
authors.lastname: Cai
authors.affiliation: 1 Department of General Surgery, Zhujiang Hospital, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Xuanjing
authors.initials: X
authors.lastname: Ning
authors.affiliation: 1 Department of General Surgery, Zhujiang Hospital, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Linyun
authors.initials: L
authors.lastname: He
authors.affiliation: 2 Guangdong Institute of Medical Instruments & National Engineering Research Center for Healthcare Devices , Guangzhou, Guangdong, China .
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.affiliation: 1 Department of General Surgery, Zhujiang Hospital, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Zonghai
authors.initials: Z
authors.lastname: Huang
authors.affiliation: 1 Department of General Surgery, Zhujiang Hospital, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Huabin
authors.initials: H
authors.lastname: Zhou
authors.affiliation: 2 Guangdong Institute of Medical Instruments & National Engineering Research Center for Healthcare Devices , Guangzhou, Guangdong, China .
authors.forename: Dequn
authors.initials: D
authors.lastname: Huang
authors.affiliation: 1 Department of General Surgery, Zhujiang Hospital, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Pusheng
authors.initials: P
authors.lastname: Zhang
authors.affiliation: 1 Department of General Surgery, Zhujiang Hospital, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Zhou
authors.initials: Z
authors.lastname: Li
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000295:instrumentation; D000818:Animals; D004598:Electrosurgery / Q000295:instrumentation* / Q000379:methods; D005260:Female; D007422:Intestines / Q000601:surgery*; D061646:Operative Time; D011312:Pressure / Q000009:adverse effects; D011897:Random Allocation; D012421:Rupture / Q000209:etiology; D013536:Suture Techniques / Q000295:instrumentation*; D013552:Swine