title: Oxygen saturation, periodic breathing and apnea during sleep in infants 1 to 4 month old living at 2,560 meters above sea level.
abstract: There are few data in the literature related to polysomnography in infants in altitudes from 2,200 m to 2,800 m. The main objective of this investigation was to describe oxygen saturation (SpO2) levels during sleep in infants aged between 1 and 4 months living at an altitude of 2,560 m. The secondary objectives were the description of periodic breathing (PB) and apnea indexes. Polysomnography was performed in 35 healthy infants 1-4 months in Cuenca (Ecuador) at 2,560 m. The median for SpO2 was 92% and 4.9% for PB. The median for the central apnea index was 23.7/hour and 15.4/hour when related to PB. No correlation was found between PB and SpO2.
  
  
  
  SpO2 was lower than the values at sea level and PB and central apnea index were higher. When apneas associated with PB were not considered, the central apnea index was similar to that found at sea level.
authors.affiliation: Departamento de Pediatría, Fundación Santa Fe de Bogotá, Bogotá
authors.forename: Santiago
authors.initials: S
authors.lastname: Ucrós
authors.affiliation: Departamentos de Pediatría y Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana.
authors.forename: Claudia
authors.initials: C
authors.lastname: Granados
authors.affiliation: Departamento de Neurología y Laboratorio de Sueño, Fundación Clínica Shaio, Bogotá, Colombia.
authors.forename: Karem
authors.initials: K
authors.lastname: Parejo
authors.affiliation: Departamento de Pediatría, Hospital del Río, Universidad del Azuay, Cuenca, Ecuador.
authors.forename: Fernando
authors.initials: F
authors.lastname: Guillén
authors.affiliation: Departamento de Pediatría, Hospital Luis Fernando Martínez, Cañar, Ecuador.
authors.forename: Fausto
authors.initials: F
authors.lastname: Ortega
authors.affiliation: Departamento de Pediatría, Hospital de La Misericordia y Fundación Santa Fe de Bogotá, Universidad de los Andes, Bogotá
authors.forename: Sonia
authors.initials: S
authors.lastname: Restrepo
authors.affiliation: Departamento de Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors.forename: Fabián
authors.initials: F
authors.lastname: Gil
authors.forename: Miriam
authors.initials: M
authors.lastname: Guillén
mesh_terms: D000531:Altitude; D003430:Cross-Sectional Studies; D004484:Ecuador; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010100:Oxygen / Q000378:metabolism*; D012119:Respiration; D012891:Sleep Apnea Syndromes / Q000378:metabolism* / Q000503:physiopathology*
chemical_list: D010100:Oxygen