title: Rational design of a novel azoimine appended maleonitrile-based Salen chemosensor for rapid naked-eye detection of copper(II) ion in aqueous media.
abstract: Achieving specific selectivity and high sensitivity for the colorimetric recognition of copper(II) ions in aqueous media over a complex background of potentially competing metal ions is inherently challenging in sensor development. Thus, a novel azo-azomethine receptor (L) based on the combination of 2-amino-3-(5-bromo-2-hydroxybenzylamino)maleonitrile and azo-coupled salicylaldehyde scaffold has been designed and synthesized for the naked-eye and rapid detection of Cu(2+) ion at trace level in a wide pH range. Accordingly, the devised chemosensor distinguished Cu(2+) from other metal ions by distinct color change from light yellow to light brown without any expensive equipment. The binding stoichiometry between Cu(2+) and L has been investigated using Job's plot and MALDI-TOF mass analysis. Remarkably, the current sensor can detect Cu(2+) ions even at 1.07 μM level, which is lower than the World Health Organization (WHO) permissible level (30 μM) in drinking water. Furthermore, sensor L was successfully utilized in the preparation of test strips for the detection of copper(II) ions from aqueous environment.
authors.affiliation: Department of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, Iran.
authors.forename: Khatereh
authors.initials: K
authors.lastname: Rezaeian
authors.affiliation: Department of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, Iran. Electronic address: h-khanmohammadi@araku.ac.ir.
authors.forename: Hamid
authors.initials: H
authors.lastname: Khanmohammadi
authors.affiliation: Department of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, Iran.
authors.forename: Vajihe
authors.initials: V
authors.lastname: Arab
mesh_terms: D060326:Chemistry Techniques, Synthetic; D003124:Colorimetry / Q000379:methods*; D003300:Copper / Q000032:analysis* / Q000378:metabolism; D005029:Ethylenediamines / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D015335:Molecular Probes / Q000138:chemical synthesis / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013055:Spectrophotometry, Infrared; D014867:Water / Q000737:chemistry
chemical_list: D005029:Ethylenediamines; D015335:Molecular Probes; D014867:Water; D003300:Copper; C011452:disalicylaldehyde ethylenediamine
keywords: Aqueous media; Azo–azomethine; Chemosensor; Colorimetric; Copper