title: Effect of Mobile Phone Radiation on Cardiovascular Development of Chick Embryo.
abstract: The biological effects on cardiovascular development of chicken embryos were examined after radiation exposure using mobile phone (900 MHz; specific absorption rate˜1.07 W/kg) intermittently 3 h per day during incubation. Samples were selected by morphological and histological methods. The results showed the rate of embryonic mortality and cardiac deformity increased significantly in exposed group (P < 0.05). No any histological pathological changes were observed on Day 5-7 (D5-D7) of incubation. A higher distribution of lipid droplets was unexpectedly present in myocardial tissue from the exposure groups on D10-D13. Soon afterwards, myofilament disruption, atrioventricular valve focal necrosis, mitochondria vacuolization and atrial natriuretic peptide (ANP) decrease appeared on D15-D21 of incubation. Comet assay data showed the haemocyte mean tail in the exposed group was significantly larger than that of the control (P < 0.01). The arterial vascular wall of exposed group was thicker (P < 0.05) than that of the control on D13, which was reversed to normal in later stages. Our findings suggest that long-term exposure of MPR may induce myocardium pathological changes, DNA damage and increased mortality; however, there was little effect on vascular development.
authors.affiliation: Medical College of Henan University, Kaifeng, 475000, China.|Institute of Zoology, School of Life Science, Lanzhou University, Lanzhou, 730000, China.
authors.forename: W
authors.initials: W
authors.lastname: Ye
authors.affiliation: Medical College of Henan University, Kaifeng, 475000, China.
authors.forename: F
authors.initials: F
authors.lastname: Wang
authors.affiliation: Medical College of Henan University, Kaifeng, 475000, China.
authors.forename: W
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Medical College of Henan University, Kaifeng, 475000, China.
authors.forename: N
authors.initials: N
authors.lastname: Fang
authors.affiliation: Medical College of Henan University, Kaifeng, 475000, China.
authors.forename: W
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Institute of Zoology, School of Life Science, Lanzhou University, Lanzhou, 730000, China.
authors.forename: J
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D009320:Atrial Natriuretic Factor / Q000378:metabolism; D040421:Cell Phone; D002478:Cells, Cultured; D002642:Chick Embryo; D004249:DNA Damage / Q000528:radiation effects*; D004574:Electromagnetic Fields / Q000009:adverse effects*; D060733:Electromagnetic Radiation; D047108:Embryonic Development / Q000528:radiation effects*; D005260:Female; D005347:Fibroblasts / Q000528:radiation effects*; D006107:Granulosa Cells / Q000528:radiation effects*; D006321:Heart / Q000196:embryology* / Q000528:radiation effects; D006351:Heart Valves / Q000473:pathology; D006801:Humans; D066292:Lipid Droplets / Q000378:metabolism / Q000528:radiation effects; D008928:Mitochondria / Q000473:pathology; D009206:Myocardium / Q000166:cytology; D051381:Rats
chemical_list: D009320:Atrial Natriuretic Factor