title: Necrotizing Fasciitis in Hematological Patients: Enterobacteriaceae Predominance and Limited Utility of Laboratory Risk Indicator for Necrotizing Fasciitis Score.
abstract: Immune suppression is a recognized risk factor for necrotizing fasciitis. In patients with hematological malignancies, a profoundly immunocompromised group, the predominant causative organisms are Gram negative. Clinical presentation and outcomes in these patients are similar to the immunocompetent. The Laboratory Risk Indicator for Necrotizing Fasciitis score is not reliable for risk stratification of the disease.
authors.affiliation: Division of Infectious Diseases , University Medicine Cluster, National University Health System , Singapore.
authors.forename: Rui Min
authors.initials: RM
authors.lastname: Foo
authors.affiliation: Department of Haematology-Oncology , National University Cancer Institute of Singapore, National University Health System.
authors.forename: Moon Ley
authors.initials: ML
authors.lastname: Tung
authors.affiliation: Department of Haematology-Oncology , National University Cancer Institute of Singapore, National University Health System.
authors.forename: Li Mei
authors.initials: LM
authors.lastname: Poon
authors.affiliation: Department of Laboratory Medicine , National University Hospital , Singapore.
authors.forename: Douglas
authors.initials: D
authors.lastname: Chan
authors.affiliation: Division of Infectious Diseases , University Medicine Cluster, National University Health System , Singapore.
authors.forename: Nares
authors.initials: N
authors.lastname: Smitasin
authors.affiliation: Department of Haematology-Oncology , National University Cancer Institute of Singapore, National University Health System.
authors.forename: Liang Piu
authors.initials: LP
authors.lastname: Koh
authors.affiliation: Department of Haematology-Oncology , National University Cancer Institute of Singapore, National University Health System ; Faculty of Medicine , Yong Loo Lin School of Medicine, National University of Singapore ; Cancer Science Institute of Singapore , National University of Singapore.
authors.forename: Wee Joo
authors.initials: WJ
authors.lastname: Chng
authors.affiliation: Division of Infectious Diseases , University Medicine Cluster, National University Health System , Singapore.
authors.forename: Louis Yi Ann
authors.initials: LY
authors.lastname: Chai
keywords: Gram negative; hematological malignancy; immunocompromised host; necrotizing fasciitis