title: Sex differences in drug addiction and response to exercise intervention: From human to animal studies.
abstract: Accumulated research supports the idea that exercise could be an option of potential prevention and treatment for drug addiction. During the past few years, there has been increased interest in investigating of sex differences in exercise and drug addiction. This demonstrates that sex-specific exercise intervention strategies may be important for preventing and treating drug addiction in men and women. However, little is known about how and why sex differences are found when doing exercise-induced interventions for drug addiction. In this review, we included both animal and human that pulled subjects from a varied age demographic, as well as neurobiological mechanisms that may highlight the sex-related differences in these potential to assess the impact of sex-specific roles in drug addiction and exercise therapies.
authors.affiliation: Department of Sport Psychology, School of Sport Science, Shanghai University of Sport, Shanghai 200438, China.
authors.forename: Yuehui
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Shanghai Mental Health Center, Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhao
authors.affiliation: Department of Sport Psychology, School of Sport Science, Shanghai University of Sport, Shanghai 200438, China. Electronic address: Chenglin_600@126.com.
authors.forename: Chenglin
authors.initials: C
authors.lastname: Zhou
authors.affiliation: Department of Sport Psychology, School of Sport Science, Shanghai University of Sport, Shanghai 200438, China; Center for Hormone Advanced Science and Education, Roskamp Institute, Sarasota, FL 34243, USA. Electronic address: rli@rfdn.org.
authors.forename: Rena
authors.initials: R
authors.lastname: Li
mesh_terms: D000818:Animals; D001519:Behavior / Q000187:drug effects* / Q000502:physiology; D015444:Exercise / Q000502:physiology / Q000523:psychology*; D005081:Exercise Therapy; D006801:Humans; D012727:Sex Characteristics; D012737:Sex Factors; D019966:Substance-Related Disorders / Q000517:prevention & control* / Q000523:psychology*
keywords: Animal and human studies; Drug addiction; Exercise; Neurobiological mechanisms; Sex differences