title: [Characteristics of pulmonary function in children with atypical asthma with chest tightness as chief complaint before and after bronchial provocation test].
abstract: OBJECTIVE
  To investigate the characteristics of pulmonary function in children with atypical asthma with chest tightness as the chief complaint before and after a bronchial provocation test.
  
  
  METHODS
  This study included 34 children with atypical asthmas who underwent bronchial provocation test between January 2010 and December 2013. Thirty-four children with typical asthmas were selected as the control group. The pulmonary function of the atypical asthma group was examined before and after the bronchial provocation test and compared with that of the control group in the acute episode and remission stages.
  
  
  RESULTS
  The forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC, peak expiratory flow, forced expiratory flow 25%, 50%, 75% (FEF25, FEF50, FEF75), and maximum mid-expiratory flow (MMEF75/25) in the atypical asthma group before the bronchial provocation test were (105±12)%, (104±12)%, (100±7)%, (88±13)%, (90±14)%, (81±17)%, (73±25)%, and (80±17)%, respectively; these functional indices were significantly higher than in the control group in the acute episode stage (P<0.05), but were similar to those of the control group in the remission stage (P>0.05). In addition, no significant difference in pulmonary indices was observed between the atypical asthma group after the bronchial provocation test and the control group in the acute episode stage (P>0.05), but functional indices above were significantly lower in the atypical asthma group after the bronchial provocation test than in the control group in the remission stage and the atypical asthma group before the bronchial provocation test (P<0.05).
  
  
  CONCLUSIONS
  Bronchial provocation test is useful in the diagnosis of atypical asthma in children.
authors.affiliation: Department of Respiratory Medicine, Anhui Provincial Children's Hospital, Hefei 230051, China. 2967847765@qq.com.
authors.forename: Wen
authors.initials: W
authors.lastname: Wei
authors.forename: Min
authors.initials: M
authors.lastname: Lv
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Shan
authors.initials: S
authors.lastname: Hua
authors.forename: Qi-Yun
authors.initials: QY
authors.lastname: Shang
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000503:physiopathology*; D001985:Bronchial Provocation Tests; D002648:Child; D005260:Female; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male