title: Mass spectrometry-based analysis of whole-grain phytochemicals.
abstract: Whole grains are a rich source of several classes of phytochemicals, such as alkylresorcinols, benzoxazinoids, flavonoids, lignans, and phytosterols. A high intake of whole grains has been linked to a reduced risk of some major noncommunicable diseases, and it has been postulated that a complex mixture of phytochemicals works in synergy to generate beneficial health effects. Mass spectrometry, especially when coupled with liquid chromatography, is a widely used method for the analysis of phytochemicals owing to its high sensitivity and dynamic range. In this review, the current knowledge of the mass spectral properties of the most important classes of phytochemicals found in cereals of common wheat, barley, oats, and rye is discussed.
authors.affiliation: a Institute of Public Health and Clinical Nutrition, University of Eastern Finland , Kuopio , Finland.
authors.forename: Ville Mikael
authors.initials: VM
authors.lastname: Koistinen
authors.affiliation: a Institute of Public Health and Clinical Nutrition, University of Eastern Finland , Kuopio , Finland.
authors.forename: Kati
authors.initials: K
authors.lastname: Hanhineva
mesh_terms: D018554:Avena / Q000737:chemistry; D048588:Benzoxazines / Q000032:analysis; D001622:Betaine / Q000032:analysis; D002338:Carotenoids / Q000032:analysis; D005419:Flavonoids / Q000032:analysis; D005504:Food Analysis / Q000379:methods*; D005511:Food Handling; D001467:Hordeum / Q000737:chemistry; D062385:Hydroxybenzoates / Q000032:analysis; D017705:Lignans / Q000032:analysis; D013058:Mass Spectrometry; D009753:Nutritive Value; D064209:Phytochemicals / Q000032:analysis*; D010840:Phytosterols / Q000032:analysis; D013107:Sphingolipids / Q000032:analysis; D024505:Tocopherols / Q000032:analysis; D014908:Triticum / Q000737:chemistry; D000067348:Whole Grains / Q000737:chemistry*; D062367:ortho-Aminobenzoates / Q000032:analysis
chemical_list: D048588:Benzoxazines; D005419:Flavonoids; D062385:Hydroxybenzoates; D017705:Lignans; D064209:Phytochemicals; D010840:Phytosterols; D013107:Sphingolipids; D062367:ortho-Aminobenzoates; D002338:Carotenoids; D001622:Betaine; C514463:avenanthramide-2C; C017616:phenolic acid; D024505:Tocopherols
keywords: Barley; fragmentation; mass spectra; oats; rye; wheat