title: [A Case of Pneumocystis Pneumonia during Chemotherapy for Recurrent Ovarian Cancer].
abstract: A 53-year-old patient with recurrent ovarian clear cell adenocarcinoma developed fever (39°C) and cough on day 28 of liposomal doxorubicin chemotherapy, the 4th cycle of the 4th regimen since initial treatment. Drug-induced interstitial pneumonia was suspected from a chest CT image showing diffuse ground-glass opacities; however, we deduced pneumocystis pneumonia from the elevated serum beta-D-glucan levels. After effective treatment with sulfamethoxazole and amphotericin B, the patient's symptoms and radiological findings improved. Pneumocystis pneumonia is an opportunistic infection that poses a risk not only for patients undergoing aggressive immunosuppressive therapy, those infected with HIV, and those with transplants, but also for patients undergoing chemotherapy. When pneumonia is diagnosed during chemotherapy, it is essential to consider the possibility of pneumocystis pneumonia.
authors.affiliation: Dept. of Obstetrics and Gynecology, Kansai Rosai Hospital.
authors.forename: Mayu
authors.initials: M
authors.lastname: Shiomi
authors.forename: Rieko
authors.initials: R
authors.lastname: Okubo
authors.forename: Kanoko
authors.initials: K
authors.lastname: Miyagi
authors.forename: Junko
authors.initials: J
authors.lastname: Murakami
authors.forename: Tomoichiro
authors.initials: T
authors.lastname: Kuwaduru
authors.forename: Kiri
authors.initials: K
authors.lastname: Uragami
authors.forename: Mio
authors.initials: M
authors.lastname: Nakagawa
authors.forename: Emi
authors.initials: E
authors.lastname: Yoshioka
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Tsuruta
authors.forename: Rina
authors.initials: R
authors.lastname: Tashima
authors.forename: Kensuke
authors.initials: K
authors.lastname: Hori
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Ito
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000188:drug therapy*; D000666:Amphotericin B / Q000627:therapeutic use; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects* / Q000627:therapeutic use; D004317:Doxorubicin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000556:secondary; D011020:Pneumonia, Pneumocystis / Q000139:chemically induced* / Q000188:drug therapy; D012008:Recurrence; D013256:Steroids / Q000627:therapeutic use
chemical_list: D000903:Antibiotics, Antineoplastic; D013256:Steroids; D000666:Amphotericin B; D004317:Doxorubicin