title: Diethylene Glycol Serving as Ethyne Equivalent: A Sustainable Approach toward 2,3-Disubstituted Furan.
abstract: In the presence of tert-butyl peroxide (TBHP), the copper-catalyzed annulation of 1,3-dicarbonyl compound with diethylene glycol was developed leading to 2,3-disubstituted furan. Diethylene glycol serves as a cheap and environmentally friendly equivalent of ethyne, with the release of H2O and alcohol as clean wastes. The procedure involves a sequential O- and C- functionalization of β-ketoester by diethylene glycol.
authors.forename: Jin-Tao
authors.initials: JT
authors.lastname: Yu
authors.affiliation: ‡Jiangsu Key Laboratory of Technologies for Polyamine, Polyol and Derived Polymers, Jiangsu Feixiang Group of Companies, Suzhou 215026, P. R. China.
authors.forename: Bo
authors.initials: B
authors.lastname: Shi
authors.forename: Haibo
authors.initials: H
authors.lastname: Peng
authors.forename: Song
authors.initials: S
authors.lastname: Sun
authors.forename: Haoke
authors.initials: H
authors.lastname: Chu
authors.forename: Yan
authors.initials: Y
authors.lastname: Jiang
authors.forename: Jiang
authors.initials: J
authors.lastname: Cheng
mesh_terms: D000114:Acetylene / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry; D005026:Ethylene Glycols / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010545:Peroxides / Q000737:chemistry*
chemical_list: D005026:Ethylene Glycols; D005663:Furans; D010545:Peroxides; C013484:diethylene glycol; D003300:Copper; C000602361:tert-butyl peroxide; D000114:Acetylene