title: Brief Report: Best Discriminators for Identifying Children with Autism Spectrum Disorder at an 18-Month Health Check-Up in Japan.
abstract: To determine the best discriminative items for identifying young children with autism spectrum disorders (ASD), we conducted a secondary analysis using longitudinal cohort data that included the Japanese version of the 23-item modified checklist for autism in toddlers (M-CHAT-JV). M-CHAT-JV data at 18 months of age and diagnostic information evaluated at age 3 or later from 1851 Japanese children was used to isolate six highly discriminative items. Using data from two different community samples (n = 1851, n = 665) these items were shown to have comparable psychometric values with those of the full version. Our results suggest that these items might work as a short form screener for early identification of ASD in primary care settings where there are time constraints on screening.
authors.affiliation: Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira-shi, Tokyo, 187-8553, Japan. ykamio@ka2.so-net.ne.jp.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Kamio
authors.affiliation: Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira-shi, Tokyo, 187-8553, Japan.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Haraguchi
authors.affiliation: Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira-shi, Tokyo, 187-8553, Japan.|Department of Human Ecology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.|Stockholm Centre for Health and Social Change (SCOHOST), Södertörn University, Huddinge, Sweden.
authors.forename: Andrew
authors.initials: A
authors.lastname: Stickley
authors.affiliation: Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira-shi, Tokyo, 187-8553, Japan.|Department of Child and Adolescent Psychiatry, Tokyo Metropolitan Children's Medical Center, Fuchu-shi, Tokyo, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Ogino
authors.affiliation: Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira-shi, Tokyo, 187-8553, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Ishitobi
authors.affiliation: Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi-cho, Kodaira-shi, Tokyo, 187-8553, Japan.
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Takahashi
mesh_terms: D000067877:Autism Spectrum Disorder / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology; D057189:Checklist / Q000379:methods / Q000592:standards; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D008403:Mass Screening / Q000379:methods / Q000592:standards*; D009819:Office Visits; D011446:Prospective Studies; D011594:Psychometrics / Q000379:methods / Q000592:standards; D012111:Residence Characteristics
keywords: Autism spectrum disorder; Modified checklist for autism in toddlers (M-CHAT); Primary care settings; Screening; Short form