title: Lemierre's Syndrome Associated with Periodontal Injury-derived Odontogenic Infection that Did Not Respond to Meropenem.
abstract: A 33-year-old previously healthy man injured his gums and subsequently developed dyspnea and fever. A chest X-ray showed nodules and infiltrates in both lungs, and the patient was initially diagnosed with pneumonia and administered meropenem hydrate, although his symptoms did not improve. A blood culture identified Fusobacterium necrophorum, and thrombophlebitis in the internal jugular vein of the neck was observed on computed tomography and ultrasound scans. We replaced the meropenem with clindamycin, sulbactam/ampicillin and metronidazole, and the patient's symptoms improved.
authors.affiliation: Department of Internal Medicine, JSDF Central Hospital, Japan.
authors.forename: Morihiko
authors.initials: M
authors.lastname: Oya
authors.forename: Takao
authors.initials: T
authors.lastname: Tanimoto
authors.forename: Takayuki
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Yukiya
authors.initials: Y
authors.lastname: Hakozaki
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002981:Clindamycin / Q000008:administration & dosage; D004417:Dyspnea / Q000209:etiology; D005334:Fever / Q000209:etiology; D005674:Fusobacterium Infections / Q000150:complications / Q000188:drug therapy*; D005675:Fusobacterium necrophorum / Q000302:isolation & purification*; D006801:Humans; D007601:Jugular Veins / Q000473:pathology*; D057831:Lemierre Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000382:microbiology; D008297:Male; D000077731:Meropenem; D008795:Metronidazole / Q000008:administration & dosage; D010518:Periodontitis / Q000150:complications* / Q000382:microbiology; D013902:Radiography, Thoracic; D013845:Thienamycins / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014946:Wound Infection / Q000150:complications / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; D008795:Metronidazole; D002981:Clindamycin; D000077731:Meropenem