title: Pre-transplant arm muscle area: a simple measure to identify patients at risk.
abstract: OBJECTIVE
  This study aims to explore parameters of nutritional assessment and food intake as predictors of clinical outcomes after hematopoietic stem cell transplant (HSCT).
  
  
  METHODS
  The study was conducted retrospectively with 56 adult patients undergoing allogeneic HSCT. Energy and protein daily intake were used to calculate the energy and protein cumulative deficit. The nutritional assessment tools were weight, body mass index (BMI), triceps skinfold (TSF), and arm muscle area (AMA) before HSCT and after HSCT.
  
  
  RESULTS
  Food intake decreased immediately after the transplant and the energy and protein cumulative deficit increased during hospitalization (p < 0.01). Almost 70 % of patients had severe weight loss (greater than 5 %), and the average percentage of weight loss was 8.5 ± 3.9 %. BMI and weight loss percentage were not correlated with the presence of acute graft versus host disease (GVHD) and mortality within 180 days in this population. On the other hand, correlation was found between the initial (pre-HSCT) AMA equal to or below the 15th percentile, with the presence of acute GVHD (p = 0.024), and mortality within 180 days after HSCT (p = 0.010).
  
  
  CONCLUSIONS
  The AMA measured pre-HSCT showed to be a potential predictor of acute GVHD and mortality up to 180 days after transplant in adult patients.
authors.affiliation: Bone Marrow Transplantation Unit, Hospital de Clínicas, Universidade Federal do Paraná, Rua General Carneiro 18, Alto da Glória, Curitiba, Paraná, 80060-900, Brazil.
authors.forename: Ana Cláudia
authors.initials: AC
authors.lastname: Thomaz
authors.affiliation: Bone Marrow Transplantation Unit, Hospital de Clínicas, Universidade Federal do Paraná, Rua General Carneiro 18, Alto da Glória, Curitiba, Paraná, 80060-900, Brazil.
authors.forename: Carolline Ilha
authors.initials: CI
authors.lastname: Silvério
authors.affiliation: Bone Marrow Transplantation Unit, Hospital de Clínicas, Universidade Federal do Paraná, Rua General Carneiro 18, Alto da Glória, Curitiba, Paraná, 80060-900, Brazil.
authors.forename: Denise Johnsson
authors.initials: DJ
authors.lastname: Campos
authors.affiliation: Bone Marrow Transplantation Unit, Hospital de Clínicas, Universidade Federal do Paraná, Rua General Carneiro 18, Alto da Glória, Curitiba, Paraná, 80060-900, Brazil.
authors.forename: Elena Emilia Moreira
authors.initials: EE
authors.lastname: Kieuteka
authors.affiliation: Department of Nutrition, Universidade Federal do Paraná, Av. Lothário Meissner 3400, Jardim Botânico, Curitiba, Paraná, 80210-170, Brazil.
authors.forename: Estela Iraci
authors.initials: EI
authors.lastname: Rabito
authors.affiliation: Bone Marrow Transplantation Unit, Hospital de Clínicas, Universidade Federal do Paraná, Rua General Carneiro 18, Alto da Glória, Curitiba, Paraná, 80060-900, Brazil.
authors.forename: Vaneuza Araújo Moreira
authors.initials: VA
authors.lastname: Funke
authors.affiliation: Department of Nutrition, Universidade Federal do Paraná, Av. Lothário Meissner 3400, Jardim Botânico, Curitiba, Paraná, 80210-170, Brazil. regina.vilela@mail.mcgill.ca.
authors.forename: Regina Maria
authors.initials: RM
authors.lastname: Vilela
mesh_terms: D000293:Adolescent; D000328:Adult; D001132:Arm / Q000502:physiology; D015992:Body Mass Index; D001835:Body Weight; D004435:Eating; D005260:Female; D006086:Graft vs Host Disease / Q000453:epidemiology* / Q000401:mortality; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000502:physiology*; D015596:Nutrition Assessment; D012189:Retrospective Studies; D016896:Treatment Outcome; D034941:Upper Extremity / Q000502:physiology; D055815:Young Adult
keywords: Body composition; Food intake; Hematopoietic stem cell transplantation; Nutritional assessment