title: Metastatic superscan on (99m)Tc-methylene diphosphonate bone scintigraphy in pediatric neuroblastoma.
abstract: Excessive skeletal radioisotope uptake in relation to soft tissues along with absent or faint activity in the genitourinary tract on bone scintigraphy (BS) is known as a "superscan." However the association of pediatric solid tumor malignancy with metastatic superscan has not been reported previously. We here describe two such cases of neuroblastoma who presented with metastatic superscan on (99m)Tc-methylene diphosphonate BS. Presence of a superscan usually indicates an advanced stage of the disease. The patient prognosis is usually poor. Though extremely rare superscan can be associated with pediatric solid tumor malignancies and should be kept in mind while reporting such cases.
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Arora
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Varun Singh
authors.initials: VS
authors.lastname: Dhull
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Anirban
authors.initials: A
authors.lastname: Mukherjee
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Shruti
authors.initials: S
authors.lastname: Tulsyan
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Behera
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Madhavi
authors.initials: M
authors.lastname: Tripathi
keywords: 99mTc-methylene diphosphonate; bone scintigraphy; metastatic; neuroblastoma; pediatric; superscan