title: Polygonifoliol, a new tirucallane triterpene from the latex of the seaside sandmat Euphorbia polygonifolia.
abstract: The genus Euphorbia contains over 2000 species which exhibit a considerable diversity of di- and triterpenes in their latex. The North American species Euphorbia polygonifolia is a low growing plant of Atlantic and Great Lake beaches. The composition of its free and esterified triterpene alcohols was determined by HPLC and (1) H-NMR analyses. An unreported triterpene alcohol was found as 2.6% and 10.3% of the free and esterified fractions, respectively. The structure of the new triterpene alcohol was determined using HMBC, and its configurational assignment was secured by acid-catalyzed isomerization to isotirucallol. The new compound, polygonifoliol, was shown to be Δ(12) -isotirucallol.
authors.affiliation: Department of Chemistry, State University of New York - ESF, Syracuse NY 13210, USA, (phone: +1-315-470-6895; fax: +1-315-470-6856). jlginer@syr.edu.
authors.forename: José-Luis
authors.initials: JL
authors.lastname: Giner
authors.affiliation: Department of Chemistry, State University of New York - ESF, Syracuse NY 13210, USA, (phone: +1-315-470-6895; fax: +1-315-470-6856).
authors.forename: Timothy N
authors.initials: TN
authors.lastname: Schroeder
mesh_terms: D002851:Chromatography, High Pressure Liquid; D028481:Euphorbia / Q000737:chemistry*; D007840:Latex / Q000737:chemistry*; D008968:Molecular Conformation; D066244:Proton Magnetic Resonance Spectroscopy; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D007840:Latex; D014315:Triterpenes; C000606359:polygonifoliol
keywords: Chemotaxonomy; Steroids; Triterpenoids