title: Putting Non-coding RNA on Display with CRISPR.
abstract: In a recent issue of Nature Methods, Shechner et al. (2015) reported the development of CRISPR Display (CRISP-Disp), which is a sophisticated, flexible, modular, and multiplexable platform for targeting different types of non-coding RNAs (ncRNAs) to genomic loci. CRISP-Disp will facilitate synthetic-biology applications and enable the elucidation of ncRNA functions.
authors.affiliation: Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
authors.forename: Pablo
authors.initials: P
authors.lastname: Perez-Pinera
authors.affiliation: Regulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Matthew F
authors.initials: MF
authors.lastname: Jones
authors.affiliation: Regulatory RNAs and Cancer Section, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Ashish
authors.initials: A
authors.lastname: Lal
authors.affiliation: Department of Electrical Engineering and Computer Science, Department of Biological Engineering, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: timlu@mit.edu.
authors.forename: Timothy K
authors.initials: TK
authors.lastname: Lu
mesh_terms: D064112:Clustered Regularly Interspaced Short Palindromic Repeats; D006801:Humans; D062085:RNA, Long Noncoding / Q000502:physiology*
chemical_list: D062085:RNA, Long Noncoding