title: Cardioprotective Properties of the Platelet P2Y12 Receptor Inhibitor, Cangrelor: Protective in Diabetics and Reliant Upon the Presence of Blood.
authors.affiliation: Hatter Cardiovascular Institute, Institute for Cardiovascular Science, University College London, 67 Chenies Mews, London, WC1E 6HX, United Kingdom.
authors.forename: R M
authors.initials: RM
authors.lastname: Bell
authors.affiliation: Hatter Cardiovascular Institute, Institute for Cardiovascular Science, University College London, 67 Chenies Mews, London, WC1E 6HX, United Kingdom.
authors.forename: V
authors.initials: V
authors.lastname: Sivaraman
authors.affiliation: Hatter Cardiovascular Institute, Institute for Cardiovascular Science, University College London, 67 Chenies Mews, London, WC1E 6HX, United Kingdom.
authors.forename: S P
authors.initials: SP
authors.lastname: Kunuthur
authors.affiliation: Department of Physiology and Cell Biology and Medicine, University of South Alabama College of Medicine, Mobile, AL, USA.
authors.forename: M V
authors.initials: MV
authors.lastname: Cohen
authors.affiliation: Department of Physiology and Cell Biology and Medicine, University of South Alabama College of Medicine, Mobile, AL, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Downey
authors.affiliation: Hatter Cardiovascular Institute, Institute for Cardiovascular Science, University College London, 67 Chenies Mews, London, WC1E 6HX, United Kingdom. d.yellon@ucl.ac.uk.
authors.forename: D M
authors.initials: DM
authors.lastname: Yellon
mesh_terms: D000249:Adenosine Monophosphate / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000818:Animals; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D048909:Diabetes Complications / Q000097:blood* / Q000517:prevention & control*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D051379:Mice; D017202:Myocardial Ischemia / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000517:prevention & control; D015428:Myocardial Reperfusion Injury / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000517:prevention & control; D058921:Purinergic P2Y Receptor Antagonists / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains; D058925:Receptors, Purinergic P2Y12 / Q000378:metabolism*
chemical_list: D002316:Cardiotonic Agents; D058921:Purinergic P2Y Receptor Antagonists; D058925:Receptors, Purinergic P2Y12; D000249:Adenosine Monophosphate; C117446:cangrelor
keywords: Anti-platelet; Cangrelor; Cardioprotection; Ischaemia; P2Y12 inhibitor; Reperfusion injury