title: Predictors of Relapse in Patients with Organizing Pneumonia.
abstract: BACKGROUND
  Although organizing pneumonia (OP) responds well to corticosteroid therapy, relapse is common during dose reduction or follow-up. Predictors of relapse in OP patients remain to be established. The aim of the present study was to identify factors related to relapse in OP patients.
  
  
  METHODS
  This study was retrospectively performed in a tertiary referral center. Of 66 OP patients who were improved with or without treatment, 20 (30%) experienced relapse. The clinical and radiologic parameters in the relapse patient group (n=20) were compared to that in the non-relapse group (n=46).
  
  
  RESULTS
  Multivariate analysis demonstrated that percent predicted forced vital capacity (FVC), PaO2/FiO2, and serum protein level were significant predictors of relapse in OP patients (odds ratio [OR], 0.82; 95% confidence interval [CI], 0.70-0.97; p=0.018; OR, 1.02; 95% CI, 1.00-1.04; p=0.042; and OR, 0.06; 95% CI, 0.01-0.87; p=0.039, respectively).
  
  
  CONCLUSIONS
  This study shows that FVC, PaO2/FiO2 and serum protein level at presentation can significantly predict relapse in OP patients.
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Minjung
authors.initials: M
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Seung-Ick
authors.initials: SI
authors.lastname: Cha
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Hyewon
authors.initials: H
authors.lastname: Seo
authors.affiliation: Department of Radiology, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Kyung-Min
authors.initials: KM
authors.lastname: Shin
authors.affiliation: Department of Radiology, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Jae-Kwang
authors.initials: JK
authors.lastname: Lim
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Hyera
authors.initials: H
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Seung-Soo
authors.initials: SS
authors.lastname: Yoo
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Jaehee
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Shin-Yup
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Chang-Ho
authors.initials: CH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Jae-Yong
authors.initials: JY
authors.lastname: Park
keywords: Cryptogenic Organizing Pneumonia; Recurrence; Vital Capacity