title: Pathological and radiological correlation in an autopsy case of combined pulmonary fibrosis and emphysema.
abstract: We report an educational autopsy case of combined pulmonary fibrosis and emphysema. Radiological patterns of the upper lung were considered as mostly emphysema, but pathological observation revealed significant interstitial fibrosis of usual interstitial pneumonia as a major pathology. The patient eventually developed acute exacerbation of background interstitial pneumonia. Careful radiological and pathological correlation of the current case indicates that regions with distal acinar emphysema on computed tomography image may possess histologically marked dense fibrosis of lethal interstitial pneumonia.
authors.affiliation: Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Karata
authors.affiliation: Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Tomonori
authors.initials: T
authors.lastname: Tanaka
authors.affiliation: Department of Radiology, Faculty of Medicine, Saga University, Saga, Japan.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Egashira
authors.affiliation: Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tabata
authors.affiliation: Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Otani
authors.affiliation: Department of Internal Medicine, University of Toyama, Faculty of Medicine, Toyama, Japan.
authors.forename: Ryuji
authors.initials: R
authors.lastname: Hayashi
authors.affiliation: Laboratory of Pathology, Toyama University Hospital, Toyama, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Hori
authors.affiliation: Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors.forename: Junya
authors.initials: J
authors.lastname: Fukuoka
mesh_terms: D000369:Aged, 80 and over; D001344:Autopsy; D001706:Biopsy; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D011656:Pulmonary Emphysema / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed
keywords: AEF; CPFE; CT; interstitial pneumonia; smoking