title: Hospital Resource Utilization and Patient Outcomes Associated with Respiratory Viral Testing in Hospitalized Patients.
abstract: Testing patients for respiratory viruses should guide isolation precautions and provide a rationale for antimicrobial drug therapies, but few studies have evaluated these assumptions. To determine the association between viral testing, patient outcomes, and care processes, we identified adults hospitalized with respiratory symptoms from 2004 through 2012 at a large, academic, tertiary hospital in Canada. Viral testing was performed in 11% (2,722/24,567) of hospital admissions and was not associated with reduced odds for death (odds ratio 0.90, 95% CI 0.76-1.10) or longer length of stay (+1 day for those tested). Viral testing resulted in more resource utilization, including intensive care unit admission, but positive test results were not associated with less antibiotic use or shorter duration of isolation. Results suggest that health care providers do not use viral test results in making management decisions at this hospital. Further research is needed to evaluate the effectiveness of respiratory infection control policies.
authors.forename: Sunita
authors.initials: S
authors.lastname: Mulpuru
authors.forename: Shawn D
authors.initials: SD
authors.lastname: Aaron
authors.forename: Paul E
authors.initials: PE
authors.lastname: Ronksley
authors.forename: Nadine
authors.initials: N
authors.lastname: Lawrence
authors.forename: Alan J
authors.initials: AJ
authors.lastname: Forster
mesh_terms: D002170:Canada / Q000453:epidemiology; D003955:Diagnostic Tests, Routine / Q000379:methods / Q000706:statistics & numerical data*; D006760:Hospitalization / Q000706:statistics & numerical data*; D006761:Hospitals / Q000592:standards / Q000706:statistics & numerical data*; D006801:Humans; D063868:Patient Outcome Assessment; D012141:Respiratory Tract Infections / Q000150:complications / Q000401:mortality* / Q000628:therapy; D014777:Virus Diseases / Q000150:complications / Q000401:mortality* / Q000628:therapy; D014780:Viruses / Q000302:isolation & purification
keywords: administrative data; infection control; isolation precautions; nasopharyngeal swabs; respiratory viruses; viruses