title: Contrast Medium-Induced Acute Kidney Injury.
abstract: Contrast medium-induced acute kidney injury (CI-AKI) is a predominant cause of hospital-acquired renal insufficiency. With an increasing number of contrast medium-enhanced radiological procedures being performed in a rapidly increasing ageing population in the Western world, it is imperative that more attention is given to understand the aetiology of CI-AKI to devise novel diagnostic methods and to formulate effective prophylactic and therapeutic regimens to reduce its incidence and its associated morbidity and mortality. This article presents high-yield information on the above-mentioned aspects of CI-AKI, primarily based on results of randomised controlled trials, meta-analyses, systematic reviews and international consensus guidelines.
authors.affiliation: Cambridge Vascular Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
authors.forename: Umar
authors.initials: U
authors.lastname: Sadat
authors.affiliation: University Department of Radiology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
authors.forename: Ammara
authors.initials: A
authors.lastname: Usman
authors.affiliation: Cambridge Vascular Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Boyle
authors.affiliation: Cambridge Vascular Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Hayes
authors.affiliation: University of Vermont College of Medicine, Division of Nephrology, Fletcher Allen Health Care, Burlington, Vt., USA.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Solomon
keywords: Acute kidney injury; Ascorbic acid; Contrast medium; N-acetylcysteine; Neutrophil gelatinase-associated lipocalcin; RenalGuard™ system; Risk prediction; Serum creatinine; Statins