title: The Korean guideline for cervical cancer screening.
abstract: The incidence rate of cervical cancer in Korea is still higher than in other developed countries, notwithstanding the national mass-screening program. Furthermore, a new method has been introduced in cervical cancer screening. Therefore, the committee for cervical cancer screening in Korea updated the recommendation statement established in 2002. The new version of the guideline was developed by the committee using evidence-based methods. The committee reviewed the evidence for the benefits and harms of the Papanicolaou test, liquid-based cytology, and human papillomavirus (HPV) testing, and reached conclusions after deliberation. The committee recommends screening for cervical cancer with cytology (Papanicolaou test or liquid-based cytology) every three years in women older than 20 years of age (recommendation A). The cervical cytology combined with HPV test is optionally recommended after taking into consideration individual risk or preference (recommendation C). The current evidence for primary HPV screening is insufficient to assess the benefits and harms of cervical cancer screening (recommendation I). Cervical cancer screening can be terminated at the age of 74 years if more than three consecutive negative cytology reports have been confirmed within 10 years (recommendation D).
authors.affiliation: Department of Obstetrics and Gynecology, Korea University Medical Center, Seoul, Korea.
authors.forename: Kyung Jin
authors.identifier: http://orcid.org/0000-0002-5783-4968
authors.initials: KJ
authors.lastname: Min
authors.affiliation: Department of Korean Gynecology, Jaseng Hospital of Korean Medicine, Seoul, Korea.
authors.forename: Yoon Jae
authors.identifier: http://orcid.org/0000-0002-1532-0942
authors.initials: YJ
authors.lastname: Lee
authors.affiliation: National Cancer Control Institute, National Cancer Center, Goyang, Korea.
authors.forename: Mina
authors.identifier: http://orcid.org/0000-0001-8101-7493
authors.initials: M
authors.lastname: Suh
authors.affiliation: Center for Uterine Cancer and Department of Pathology, National Cancer Center, Goyang, Korea.
authors.forename: Chong Woo
authors.identifier: http://orcid.org/0000-0002-5221-4516
authors.initials: CW
authors.lastname: Yoo
authors.affiliation: Center for Uterine Cancer, Hospital, Gynecologic Cancer Branch, Research Institute, Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea.
authors.forename: Myong Cheol
authors.identifier: http://orcid.org/0000-0001-8964-7158
authors.initials: MC
authors.lastname: Lim
authors.affiliation: Department of Family Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Jaekyung
authors.identifier: http://orcid.org/0000-0002-0875-7505
authors.initials: J
authors.lastname: Choi
authors.affiliation: Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea.
authors.forename: Moran
authors.identifier: http://orcid.org/0000-0002-8892-7104
authors.initials: M
authors.lastname: Ki
authors.affiliation: Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Yong Man
authors.identifier: http://orcid.org/0000-0003-3391-4426
authors.initials: YM
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Jae Weon
authors.identifier: http://orcid.org/0000-0003-1835-9436
authors.initials: JW
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jea Hoon
authors.identifier: http://orcid.org/0000-0001-6599-7065
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Family Medicine, Dankook University College of Medicine, Cheonan, Korea.
authors.forename: Eal Whan
authors.identifier: http://orcid.org/0000-0003-4421-5655
authors.initials: EW
authors.lastname: Park
authors.affiliation: Department of Social Medicine, Dankook University College of Medicine, Cheonan, Korea.
authors.forename: Hoo Yeon
authors.identifier: http://orcid.org/0000-0002-8426-2045
authors.initials: HY
authors.lastname: Lee
authors.affiliation: Department of Pathology, Chosun University School of Medicine, Gwangju, Korea.
authors.forename: Sung Chul
authors.identifier: http://orcid.org/0000-0003-3912-2809
authors.initials: SC
authors.lastname: Lim
authors.affiliation: Department of Obstetrics and Gynecology, Keimyung University School of Medicine, Daegu, Korea.
authors.forename: Chi Heum
authors.identifier: http://orcid.org/0000-0002-0437-4099
authors.initials: CH
authors.lastname: Cho
authors.affiliation: Department of Pathology, Cheil General Hospital & Women's Healthcare Center, Dankook University College of Medicine, Seoul, Korea.
authors.forename: Sung Ran
authors.identifier: http://orcid.org/0000-0002-6828-2345
authors.initials: SR
authors.lastname: Hong
authors.affiliation: National Cancer Control Institute, National Cancer Center, Goyang, Korea.
authors.forename: Ji Yeon
authors.identifier: http://orcid.org/0000-0002-8151-2520
authors.initials: JY
authors.lastname: Dang
authors.affiliation: Department of Family Medicine, Hallym University Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Soo Young
authors.identifier: http://orcid.org/0000-0002-3205-9408
authors.initials: SY
authors.lastname: Kim
authors.affiliation: National Cancer Control Institute, National Cancer Center, Goyang, Korea.
authors.forename: Yeol
authors.identifier: http://orcid.org/0000-0003-1142-1559
authors.initials: Y
authors.lastname: Kim
authors.affiliation: Department of Preventive Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Won Chul
authors.identifier: http://orcid.org/0000-0002-5483-1614
authors.initials: WC
authors.lastname: Lee
authors.affiliation: Department of Obstetrics and Gynecology, Korea University Medical Center, Seoul, Korea. jklee38@gmail.com.
authors.forename: Jae Kwan
authors.identifier: http://orcid.org/0000-0003-3101-6403
authors.initials: JK
authors.lastname: Lee
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D055088:Early Detection of Cancer / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D019317:Evidence-Based Medicine; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000175:diagnosis; D053918:Papillomavirus Vaccines; D018579:Patient Selection; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis; D056910:Republic of Korea; D012196:Review Literature as Topic; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*; D014626:Vaginal Smears / Q000009:adverse effects / Q000379:methods / Q000592:standards; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines
keywords: Mass Screening; Papanicolaou Test; Uterine Cervical Neoplasms