title: Intrahepatic bile duct adenoma (peribiliary gland hamartoma): a case report and review of literature.
abstract: Bile duct adenoma (BDA) is a comparatively rare disease and there are relatively few reported cases in the English-language literature. Herein, we present a 63-year-old woman, who was incidentally found to have a liver-occupying lesion during a routine medical examination. Ultrasonography suggested "quick wash-in and wash-out" sign with an obvious nodular enhancement in the peripheral of the right intrahepatic nodular. Computed tomography revealed a 33 mm×25 mm×28 mm mass in the right hepatic segment. The patient underwent a liver tumor resection. Histological examination showed that the tumor was consisted of small heterogeneous tubular ducts with fibrous tissues and several inflammatory cells, without cell atypia and mitotic activity. Immunohistochemically, the tumor cells were positive for CK19, CK7, CD56 and CD10. The final histopathological diagnosis was intrahepatic BDA.
authors.affiliation: Department of Pathology, Shaoxing People's Hospital Shaoxing, Zhejiang Province, P. R China.
authors.forename: Jianguo
authors.initials: J
authors.lastname: Wei
authors.affiliation: Department of Pathology, Beijing Xuanwu TCM Hospital Beijing, P. R China.
authors.forename: Dongmei
authors.initials: D
authors.lastname: Zhang
authors.affiliation: Department of Radiology, Shaoxing People's Hospital Shaoxing, Zhejiang Province, P. R China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Pathology, The General Military Hospital of Beijing PLA Beijing, P. R China.
authors.forename: Chunwei
authors.initials: C
authors.lastname: Xu
mesh_terms: D000236:Adenoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D001650:Bile Duct Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D001653:Bile Ducts, Intrahepatic / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D005260:Female; D006222:Hamartoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006498:Hepatectomy; D006801:Humans; D007150:Immunohistochemistry; D033162:Incidental Findings; D008279:Magnetic Resonance Imaging; D008875:Middle Aged
chemical_list: D014408:Biomarkers, Tumor
keywords: Liver; bile duct adenoma; peribiliary gland hamartoma