title: PTHrP-Induced Refractory Malignant Hypercalcemia in a Patient With Chronic Lymphocytic Leukemia Responding to Denosumab.
authors.affiliation: Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: Ameen A
authors.initials: AA
authors.lastname: Salahudeen
authors.affiliation: Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: Arjun
authors.initials: A
authors.lastname: Gupta
authors.affiliation: Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: Jeremy C
authors.initials: JC
authors.lastname: Jones
authors.affiliation: Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Cowan
authors.affiliation: Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX; Simmons Cancer Center, Division of Medical Oncology, University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: Madhuri
authors.initials: M
authors.lastname: Vusirikala
authors.affiliation: Simmons Cancer Center, Division of Medical Oncology, University of Texas Southwestern Medical Center, Dallas, TX.
authors.forename: Chi
authors.initials: C
authors.lastname: Kwong
authors.affiliation: Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX; Simmons Cancer Center, Division of Medical Oncology, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address: harris.naina@utsouthwestern.edu.
authors.forename: Harris V K
authors.initials: HV
authors.lastname: Naina
mesh_terms: D000328:Adult; D000069448:Denosumab / Q000627:therapeutic use*; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000378:metabolism* / Q000473:pathology; D008297:Male; D010257:Paraneoplastic Syndromes / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D044162:Parathyroid Hormone-Related Protein / Q000378:metabolism*
chemical_list: D044162:Parathyroid Hormone-Related Protein; D000069448:Denosumab
keywords: CLL; Denosumab; Humoral hypercalcemia; Hypercalcemia of malignancy; PTHrP; Parathyroid hormone–related protein