title: Clearance Rate of Carbapenemase-Producing Enterobacteriaceae Carriage Among Hospitalized Patients.
abstract: During the past decade, carbapenemase-producing Enterobacteriaceae (CPE) has emerged and spread across the world. 1 The major carbapenemase enzymes currently being reported are KPC, NDM-1, VIM, IMP, and OXA. 2 Because carbapenemase can be effectively transmitted via mobile genetic elements, and current therapeutic options for CPE infections are extremely limited, CPE may be one of the most serious contemporary threats to public health. However, very little is known about the characteristics of CPE carriage during hospitalization. The aims of this study were to investigate the clearance rate of CPE carriage and determine the number of consecutive negative cultures required to confirm CPE clearance. We also examined CPE transmission among hospitalized patients.
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Kyu-Ri
authors.initials: KR
authors.lastname: Kim
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Jeong-Young
authors.initials: JY
authors.lastname: Lee
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Hee-Youn
authors.initials: HY
authors.lastname: Park
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Sun-Hee
authors.initials: SH
authors.lastname: Kwak
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Young-Ju
authors.initials: YJ
authors.lastname: Lim
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Min-Jee
authors.initials: MJ
authors.lastname: Hong
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Sun-Kyung
authors.initials: SK
authors.lastname: Kim
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: So-Yeon
authors.initials: SY
authors.lastname: Park
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Hyeon-Jeong
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Hye-Suk
authors.initials: HS
authors.lastname: Choi
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Mi-Na
authors.initials: MN
authors.lastname: Kim
authors.affiliation: 3Department of Clinical Nursing,University of Ulsan College of Medicine,Seoul,Republic of Korea.
authors.forename: Hye-Ran
authors.initials: HR
authors.lastname: Choi
authors.affiliation: 4Department of Nursing,University of Ulsan,Seoul,Republic of Korea.
authors.forename: Jae-Sim
authors.initials: JS
authors.lastname: Jeong
authors.affiliation: 1Office for Infection Control,Asan Medical Center,Seoul,Republic of Korea.
authors.forename: Sang-Ho
authors.initials: SH
authors.lastname: Choi
mesh_terms: D000368:Aged; D001426:Bacterial Proteins; D001431:Bacteriological Techniques; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D004755:Enterobacteriaceae / Q000201:enzymology / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D001618:beta-Lactamases
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase