title: Atypical diagnosis diagnosis by endoscopic capsule: Whipple's disease.
abstract: Whipple's disease is a chronic systemic infection produced by the actinomycete Tropheryma whipplei. Endoscopic tests are key in the diagnosis as they allow biopsy and histopathological examination for definitive diagnosis of this entity. We present a case of Whipple's disease where capsule endoscopy, uncommon for the diagnosis of this condition, was essential for it and its performance before and after antibiotic treatment allows to describe the macroscopic evolution of the findings in the small bowel. This case illustrates the utility of capsule endoscopy to allow complete examination of the small bowel disease in which up to 30% of patients may present with normal endoscopy.
authors.affiliation: Aparato Digestivo, Hospital Clínico San Carlos. Madrid, ESPAÑA.
authors.forename: Alba
authors.initials: A
authors.lastname: Martínez-Sánchez
authors.affiliation: Digestivo, Hospital Clínico San Carlos, España.
authors.forename: Francisco L
authors.initials: FL
authors.lastname: Sánche- Ceballos
authors.affiliation: Aparato Digestivo, Hospital Clínico San Carlos. Madrid, España.
authors.forename: Servando
authors.initials: S
authors.lastname: Fernández-Díez
authors.affiliation: Servicio de Anatomía Patológica, Hospital Clínico San Carlos. Madrid, ESPAÑA.
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Suárez-Solís
authors.affiliation: Aparato Digestivo, Hospital Clínico San Carlos. Madrid, ESPAÑA.
authors.forename: Matilde
authors.initials: M
authors.lastname: Asteinza-Daganzo
authors.affiliation: Aparato Digestivo, Hospital Clínico San Carlos. Madrid, ESPAÑA.
authors.forename: Walid
authors.initials: W
authors.lastname: Baki
authors.affiliation: Endoscopia, Hospital Clinico San Carlos, SPAIN.
authors.forename: José Miguel
authors.initials: JM
authors.lastname: Esteban
authors.affiliation: Aparato Digestivo, Hospital Clínico San Carlos, España.
authors.forename: Enrique
authors.initials: E
authors.lastname: Rey-Díaz-Rubio
mesh_terms: D053705:Capsule Endoscopes; D053704:Capsule Endoscopy / Q000379:methods*; D006801:Humans; D007421:Intestine, Small / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D008061:Whipple Disease / Q000000981:diagnostic imaging* / Q000188:drug therapy