title: Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant.
abstract: We report the use of fecal microbiota transplantation in a single heart-kidney transplant recipient with recurrent Clostridium difficile, vancomycin-resistant Enterococcus (VRE) fecal dominance, and recurrent VRE infections. Fecal microbiota transplantation resulted in the reconstruction of a diverse microbiota with (1) reduced relative abundance of C difficile and VRE and (2) positive clinical outcome.
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: Joshua
authors.initials: J
authors.lastname: Stripling
authors.affiliation: Center for Clinical and Translational Sciences.
authors.forename: Ranjit
authors.initials: R
authors.lastname: Kumar
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: John W
authors.initials: JW
authors.lastname: Baddley
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: Anoma
authors.initials: A
authors.lastname: Nellore
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: Paula
authors.initials: P
authors.lastname: Dixon
authors.affiliation: Departments of Pathology.
authors.forename: Donna
authors.initials: D
authors.lastname: Howard
authors.affiliation: Microbiology.
authors.forename: Travis
authors.initials: T
authors.lastname: Ptacek
authors.affiliation: Center for Clinical and Translational Sciences ; Microbiology.
authors.forename: Elliot J
authors.initials: EJ
authors.lastname: Lefkowitz
authors.affiliation: Division of Cardiology, Department of Medicine.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Tallaj
authors.affiliation: Departments of Pathology.
authors.forename: William H
authors.initials: WH
authors.lastname: Benjamin
authors.affiliation: Department of Cell, Developmental and Integrative Biology , University of Alabama at Birmingham.
authors.forename: Casey D
authors.initials: CD
authors.lastname: Morrow
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: J Martin
authors.initials: JM
authors.lastname: Rodriguez
keywords: C difficile; VRE; fecal microbiota transplant; gut microbiome; vancomycin-resistant Enterococcus