title: The association between ischemia modified albumin and placental histopathology in uncomplicated term deliveries.
abstract: Ischemia modified albumin (IMA) is a marker of ischemia elevated in different clinical conditions and its use for hypoxia in perinatology is of current interest. We aimed to investigate the association between maternal and cord blood IMA levels and placental histopathological findings in uncomplicated term deliveries. In this study, placental histopathological evaluation in uncomplicated deliveries that ended with healthy newborns revealed 80.6% vasculopathy. The results support the hypothesis that hypoxia exceeding the placental reserve ends with fetal compromise. Moreover, the presence of maternal vasculopathy in placenta is not correlated with maternal and fetal IMA levels.
authors.affiliation: Ufuk University Faculty of Medicine, Department of Obstetrics and Gynecology, Mevlana Bulvari, No:86 Balgat, Ankara, Turkey. Electronic address: minekiseli@gmail.com.
authors.forename: Mine
authors.initials: M
authors.lastname: Kiseli
authors.affiliation: Ufuk University Faculty of Medicine, Department of Obstetrics and Gynecology, Mevlana Bulvari, No:86 Balgat, Ankara, Turkey.
authors.forename: Aslı Yarci
authors.initials: AY
authors.lastname: Gürsoy
authors.affiliation: Ufuk University Faculty of Medicine, Department of Pathology, Mevlana Bulvari, No:86 Balgat, Ankara, Turkey.
authors.forename: Egemen
authors.initials: E
authors.lastname: Akincioglu
authors.affiliation: Ufuk University Faculty of Medicine, Department of Obstetrics and Gynecology, Mevlana Bulvari, No:86 Balgat, Ankara, Turkey.
authors.forename: Gamze Sinem
authors.initials: GS
authors.lastname: Çağlar
authors.affiliation: Ufuk University Faculty of Medicine, Department of Biochemistry, Mevlana Bulvari, No:86 Balgat, Ankara, Turkey.
authors.forename: Tuba
authors.initials: T
authors.lastname: Çandar
authors.affiliation: Ufuk University Faculty of Medicine, Department of Biochemistry, Mevlana Bulvari, No:86 Balgat, Ankara, Turkey.
authors.forename: Selda
authors.initials: S
authors.lastname: Demirtaş
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D006801:Humans; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy / Q000097:blood*; D011446:Prospective Studies; D012709:Serum Albumin; D000075462:Serum Albumin, Human; D055815:Young Adult
chemical_list: D015415:Biomarkers; D012709:Serum Albumin; C561522:ischemia-modified albumin; D000075462:Serum Albumin, Human
keywords: Cord blood; Delivery; Fetal hypoxia; Ischemia modified albumin; Placenta