title: Impact of hand hygiene on the infectious risk in nursing home residents: A systematic review.
abstract: In nursing homes, the infectious risk is high, making infection control using approaches such as hand hygiene (HH) a major issue. However, the effectiveness of HH in these settings is not well documented, and HH compliance is low.
  
  
  
  We systematically searched PubMed, Scopus, Web of Science, and Cochrane Clinical Trials for studies in nursing homes that either described a HH-related intervention or assessed HH compliance and included a measured infectious outcome. Two reviewers independently performed the study selection.
  
  
  
  Fifty-six studies met the inclusion criteria and were reviewed. Most were outbreak reports (39%), followed by observational studies (23%), controlled trials (23%), and before-after intervention studies (14%). Thirty-five studies (63%) reported results in favor of HH on at least one of their outcome measures; in addition, the infection control success rate was higher when at least one HH-related intervention (eg, staff education on HH, increased availability of handrub solution) was included (70% vs 30% for no intervention). However, only 25% of randomized trials concluded that HH-related interventions led to a reduction in the infectious risk.
  
  
  
  The results of this systematic review suggest that more evidence on HH effectiveness in nursing homes is needed. Future interventional studies should enhance methodologic rigor using clearly defined outcome measures, standardized reporting of findings, and a relevant HH observation tool.
authors.affiliation: Laboratoire Modélisation, Epidémiologie et Surveillance des Risques Sanitaires, Conservatoire national des arts et métiers, Paris, France.
authors.forename: Mounia N
authors.initials: MN
authors.lastname: Hocine
authors.affiliation: Laboratoire Modélisation, Epidémiologie et Surveillance des Risques Sanitaires, Conservatoire national des arts et métiers, Paris, France. Electronic address: laura.temime@cnam.fr.
authors.forename: Laura
authors.initials: L
authors.lastname: Temime
mesh_terms: D019983:Guideline Adherence; D063373:Hand Hygiene / Q000592:standards*; D006801:Humans; D017053:Infection Control / Q000379:methods*; D009735:Nursing Homes / Q000592:standards*; D012189:Retrospective Studies; D012306:Risk
keywords: Hand hygiene; Infectious risk; Long-term care facilities; Nursing homes