title: Central Macular Thickness in Children with Myopia, Emmetropia, and Hyperopia: An Optical Coherence Tomography Study.
abstract: OBJECTIVE
  To investigate the central macular thickness (CMT) in myopic, emmetropic, and hyperopic Chinese children using Optical Coherence Tomography.
  
  
  METHODS
  168 right eyes of Chinese subjects aged 4-18 were divided into 3 groups based on their postcycloplegic spherical equivalent: myopes (<-1.0 D); emmetropes (≥-1.0 to ≤+1.0 D); and hyperopes (>+1.0 D) and the CMT was compared before/after age adjustment. The CMT was correlated with age, axial length, and peripapillary retinal nerve fibre layer (RNFL).
  
  
  RESULTS
  The mean CMT was 274.9 ± 50.3 μm and the mean population age was 7.6 ± 3.3 years. The CMT was thickest in the myopes (283.3 ± 57.3 μm, n = 56), followed by the hyperopes (266.2 ± 55.31 μm, n = 60) and then emmetropes (259.8 ± 28.7 μm, n = 52) (all P < 0.0001). When adjusted for age, myopes had a thicker CMT than the other 2 groups (all P < 0.0001) but there was no CMT difference between the emmetropes and hyperopes (P > 0.05). There was no significant correlation between CMT with age, axial length, or peripapillary RNFL (all P ≥ 0.2).
  
  
  CONCLUSIONS
  Chinese children with myopia had a thicker CMT than those with emmetropia or hyperopia. There was no correlation of the CMT with age, axial length, or peripapillary RNFL thickness.
authors.affiliation: Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong.
authors.forename: Gordon S K
authors.initials: GS
authors.lastname: Yau
authors.affiliation: Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong ; Department of Ophthalmology, University of Hong Kong, Room 301, Level 3 Block B, Cyberport 4, 100 Cyberport Road, Hong Kong.
authors.forename: Jacky W Y
authors.initials: JW
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong.
authors.forename: Tiffany T Y
authors.initials: TT
authors.lastname: Woo
authors.affiliation: Department of Ophthalmology and Visual Sciences, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong.
authors.forename: Raymond L M
authors.initials: RL
authors.lastname: Wong
authors.affiliation: Department of Ophthalmology, University of Hong Kong, Room 301, Level 3 Block B, Cyberport 4, 100 Cyberport Road, Hong Kong.
authors.forename: Ian Y H
authors.initials: IY
authors.lastname: Wong
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D058453:Emmetropia; D005260:Female; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D006956:Hyperopia / Q000453:epidemiology / Q000473:pathology*; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D009216:Myopia / Q000453:epidemiology / Q000473:pathology*; D041623:Tomography, Optical Coherence