title: Cardiac Amyloidosis Presenting With Cardiogenic Shock.
abstract: Cardiac amyloidosis is an infiltrative disorder of the myocardium. It is the result of one of 4 types of amyloidosis: primary systemic (immunoglobulin light chain), secondary, familial (hereditary), or senile. Cardiac amyloidosis ultimately causes congestive heart failure due to irreversible restrictive cardiomyopathy. Because of the rapid progression of the disease, early recognition and determination of underlying etiology are important for tailored therapy. Current interventions range from conservative heart failure management to autologous stem cell and heart transplantation. We present a case of cardiac amyloidosis accompanying undiagnosed multiple myeloma to illustrate the rapid progression of the disease and the complexities of diagnosing and treating this disorder.
authors.affiliation: 1Department of Medicine, New York Methodist Hospital, Brooklyn, NY; 2Department of Pathology, Weill Cornell Medical Center, New York, NY; and 3Department of Cardiothoracic Surgery, New York Methodist Hospital, Brooklyn, NY.
authors.forename: Ashwad
authors.initials: A
authors.lastname: Afzal
authors.forename: Sorin J
authors.initials: SJ
authors.lastname: Brener
authors.forename: Navneet
authors.initials: N
authors.lastname: Narula
authors.forename: Berhane
authors.initials: B
authors.lastname: Worku
authors.forename: Iosif
authors.initials: I
authors.lastname: Gulkarov
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004562:Electrocardiography; D006333:Heart Failure / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000139:chemically induced*; D012770:Shock, Cardiogenic / Q000150:complications*