title: Genetic Classification of Gliomas: Refining Histopathology.
abstract: Newly published studies validate prior reports that specific combinations of genetic alternations in IDH1/2, ATRX, TERT, TP53, and co-deletion of 1p/19q have the ability to reclassify gliomas into rational subsets, defining a glioma's biological and clinical behavior more accurately than stratifications based solely on histopathology.
authors.affiliation: The Swim Across America Laboratory at Johns Hopkins, Baltimore, MD 21287, USA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA; The Ludwig Center for Cancer Genetics and Therapeutic at Johns Hopkins, Baltimore, MD 21287, USA.
authors.forename: Michael B
authors.initials: MB
authors.lastname: Foote
authors.affiliation: The Swim Across America Laboratory at Johns Hopkins, Baltimore, MD 21287, USA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA; The Ludwig Center for Cancer Genetics and Therapeutic at Johns Hopkins, Baltimore, MD 21287, USA.
authors.forename: Nickolas
authors.initials: N
authors.lastname: Papadopoulos
authors.affiliation: The Swim Across America Laboratory at Johns Hopkins, Baltimore, MD 21287, USA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA; The Ludwig Center for Cancer Genetics and Therapeutic at Johns Hopkins, Baltimore, MD 21287, USA. Electronic address: ldiaz1@jhmi.edu.
authors.forename: Luis A
authors.initials: LA
authors.lastname: Diaz
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D001932:Brain Neoplasms / Q000235:genetics / Q000473:pathology*; D042822:Genomic Instability; D005910:Glioma / Q000235:genetics / Q000473:pathology*; D006801:Humans; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor