title: Relapse with Dysphagia in a Case of Chronic Inflammatory Demyelinating Polyradiculoneuropathy.
abstract: Glossopharyngeal and/or vagus nerve involvement is infrequent in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). We herein report the case of a 69-year-old Japanese woman who presented with muscle weakness and numbness of the extremities with dysphagia. The serum anti-ganglioside GM1 immunoglobulin IgM antibody levels were elevated, and treatment with intravenous immunoglobulin (IVIg) resulted in a dramatic improvement; the weakness, numbness and dysphagia all resolved. However, relapse comprising dysphagia alone occurred on hospital day 26, and treatment with IVIg again proved extremely effective. IVIg therapy can be effective against cranial nerve involvement in cases of CIDP.
authors.affiliation: Division of Neurology, Department of Medicine, Nihon University School of Medicine, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Teramoto
authors.forename: Akihiko
authors.initials: A
authors.lastname: Morita
authors.forename: Makoto
authors.initials: M
authors.lastname: Hara
authors.forename: Satoko
authors.initials: S
authors.lastname: Ninomiya
authors.forename: Shuntaro
authors.initials: S
authors.lastname: Shigihara
authors.forename: Susumu
authors.initials: S
authors.lastname: Kusunoki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kamei
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003680:Deglutition Disorders / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005930:Glossopharyngeal Nerve / Q000473:pathology*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007155:Immunologic Factors / Q000627:therapeutic use*; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence; D014630:Vagus Nerve / Q000473:pathology*
chemical_list: D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D011239:Prednisolone