title: [Current state and potential of pharmacogenetic studies in the treatment of depression].
abstract: In this literature review, we consider pharmacological studies in the aspect of functioning of cerebral neurochemical systems and their role in the development of depression and mechanisms of antidepressant action. The following sections of the review are devoted to the above issues: adrenoreceptors, serotonin transporter protein, dopamine transporter protein, monoamine oxidase A, catechol-O-methyltransferase, brain-derived neurotrophic factor, the hypothalamic-pituitary-adrenal system, G-proteins, the glutamatergic system.
authors.affiliation: Sechenov First Moscow State Medical University, Moscow.
authors.forename: N N
authors.initials: NN
authors.lastname: Ivanets
authors.affiliation: Sechenov First Moscow State Medical University, Moscow.
authors.forename: Yu G
authors.initials: YG
authors.lastname: Tikhonova
authors.affiliation: Sechenov First Moscow State Medical University, Moscow.
authors.forename: M A
authors.initials: MA
authors.lastname: Kinkulkina
authors.affiliation: Sechenov First Moscow State Medical University, Moscow.
authors.forename: T I
authors.initials: TI
authors.lastname: Avdeeva
mesh_terms: D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001921:Brain / Q000378:metabolism*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000235:genetics*; D006801:Humans; D010597:Pharmacogenetics; D011110:Polymorphism, Genetic
chemical_list: D000928:Antidepressive Agents