title: Bicuspid Pulmonic Valve and Pulmonary Artery Aneurysm.
abstract: Bicuspid pulmonary valves and pulmonary artery aneurysms are two rare entities, reported in association, and usually attributed to hemodynamic alterations caused by the bicuspid pulmonary valve. We present magnetic resonance images of a patient with a bicuspid pulmonary valve and pulmonary artery aneurysm, and propose an alternative mechanism for this association, based on recent embryologic studies that link anomalies of the semilunar valves and great vessels with derangement of the cardiac neural crest cell development.
authors.affiliation: Department of Radiology, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Jamis-Dow
authors.affiliation: Cardiology Section, Bay Pines VA Healthcare System, Bay Pines, Florida, USA.
authors.forename: George H
authors.initials: GH
authors.lastname: Barbier
authors.affiliation: Consortium for Translational Research in Advanced Imaging and Nanomedicine (C-TRAIN), Washington University of Saint Louis, St Louis, Missouri, USA.
authors.forename: Mary P
authors.initials: MP
authors.lastname: Watkins
authors.affiliation: Consortium for Translational Research in Advanced Imaging and Nanomedicine (C-TRAIN), Washington University of Saint Louis, St Louis, Missouri, USA.
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Lanza
authors.affiliation: Consortium for Translational Research in Advanced Imaging and Nanomedicine (C-TRAIN), Washington University of Saint Louis, St Louis, Missouri, USA.
authors.forename: Shelton D
authors.initials: SD
authors.lastname: Caruthers
authors.affiliation: Consortium for Translational Research in Advanced Imaging and Nanomedicine (C-TRAIN), Washington University of Saint Louis, St Louis, Missouri, USA.
authors.forename: Samuel A
authors.initials: SA
authors.lastname: Wickline
keywords: Bicuspid pulmonic valve; Neural crest cells; Pulmonary artery aneurysm