title: Establishing the UK DNA Bank for motor neuron disease (MND).
abstract: In 2003 the Motor Neurone Disease (MND) Association, together with The Wellcome Trust, funded the creation of a national DNA Bank specific for MND. It was anticipated that the DNA Bank would constitute an important resource to researchers worldwide and significantly increase activity in MND genetic research. The DNA Bank houses over 3000 high quality DNA samples, all of which were donated by people living with MND, family members and non-related controls, accompanied by clinical phenotype data about the patients. Today the primary focus of the UK MND DNA Bank still remains to identify causative and disease modifying factors for this devastating disease.
authors.affiliation: Motor Neurone Disease Association, PO Box 246, Northampton, NN1 2PR, UK. lucy.smith@mndassociation.org.
authors.forename: Lucy
authors.initials: L
authors.lastname: Smith
authors.affiliation: Motor Neurone Disease Association, PO Box 246, Northampton, NN1 2PR, UK. belinda.cupid@mndassociation.org.
authors.forename: B C
authors.initials: BC
authors.lastname: Cupid
authors.affiliation: Motor Neurone Disease Association, PO Box 246, Northampton, NN1 2PR, UK. brian.dickie@mndassociation.org.
authors.forename: B G M
authors.initials: BG
authors.lastname: Dickie
authors.affiliation: NIHR Biomedical Research Unit in Dementia, Department of Clinical Neuroscience, King's College London, London, SE5 8AF, UK. ammar.al-chalabi@kcl.ac.uk.
authors.forename: A
authors.initials: A
authors.lastname: Al-Chalabi
authors.affiliation: Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. k.morrison@bham.ac.uk.
authors.forename: K E
authors.initials: KE
authors.lastname: Morrison
authors.affiliation: NIHR Biomedical Research Unit in Dementia, Department of Clinical Neuroscience, King's College London, London, SE5 8AF, UK. chris.shaw@kcl.ac.uk.
authors.forename: C E
authors.initials: CE
authors.lastname: Shaw
authors.affiliation: Sheffield Institute for Translational Neuroscience, University of Sheffield, 385A Glossop Road, Sheffield, S10 2HQ, UK. pamela.shaw@sheffield.ac.uk.
authors.forename: P J
authors.initials: PJ
authors.lastname: Shaw
mesh_terms: D018070:Biological Specimen Banks / Q000592:standards; D004247:DNA; D006801:Humans; D016472:Motor Neuron Disease / Q000235:genetics*; D011786:Quality Control; D013048:Specimen Handling; D006113:United Kingdom
chemical_list: D004247:DNA