title: [The current concept of augmentation of treatment efficiency with antidepressant medication].
abstract: The introduction into clinical practice of new and highly effective antidepressants has certainly helped to resolve the problem of depression therapy. However, achieving a complete remission, which is a key point for therapy in depressed patients, remains a difficult task. It is known that a significant number of patients do not respond to antidepressants. So, special attention has been paid in recent years towards investigation of methods that could improve the treatment effectiveness in depressive. In this review presents the results of clinical trials of buspirone as an adjunctive therapy in cases with previous ineffective use of antidepressants in patients with major depressive disorder.
authors.affiliation: Sechenov First Moscow State Medical University, Moscow.
authors.forename: I V
authors.initials: IV
authors.lastname: Damulin
authors.affiliation: Sechenov First Moscow State Medical University, Moscow.
authors.forename: I A
authors.initials: IA
authors.lastname: Suvorova
mesh_terms: D014151:Anti-Anxiety Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D002065:Buspirone / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003865:Major Depressive Disorder / Q000188:drug therapy*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006801:Humans; D012074:Remission Induction
chemical_list: D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents; D002065:Buspirone