title: Infectious Mononucleosis Complicated with Acute Cerebral Infarction: A Case Report.
abstract: OBJECTIVE
  Infectious mononucleosis (IM) complicated with a neurological manifestation, including acute cerebellar ataxia, Guillain-Barre syndrome, meningitis, encephalitis, cranial nerve palsies, optic neuritis or transverse myelitis, has been rarely reported; however, IM complicated with acute cerebral infarction has never been reported in the literature.
  
  
  METHODS
  A 49-year-old man with diabetic mellitus suffered from IM with fever, pharyngitis, parotiditis with lymphadenopathies, thrombocytopenia and splenomegaly. After two weeks of conservative treatment, left upper limb paresis and left hemihypesthesia occurred. Neuroimaging demonstrated acute ischemic stroke involving the right frontal lobe. In view of the underlying infection, immediate intravenous rt-PA was not recommended; hence, oral aspirin 100 mg daily was prescribed and he received regular rehabilitation in the subsequent follow up.
  
  
  CONCLUSIONS
  Although IM is known to be self-limited, it could contribute to acute cerebral infarction, which is a rare IM neurological complication.
authors.affiliation: Department of Neuro-Medical Scientific Center, Buddhist Tzu Chi General Hospital, Taichung Branch, Taichung.
authors.forename: Jiann-Jy
authors.initials: JJ
authors.lastname: Chen
authors.affiliation: Faculty of Chinese Medicine, Chinese Medical College, China Medical University, Taichung.
authors.forename: Hsin-Feng
authors.initials: HF
authors.lastname: Chang
authors.affiliation: Department of Neurology, Buddhist Tzu Chi General Hospital, Taipei Branch, New Taipei, Taiwan.
authors.forename: Chih-Yang
authors.initials: CY
authors.lastname: Liu
authors.affiliation: G-Home Clinic for Otorhinolaryngology and Neurology, Kaohsiung, Taiwan.
authors.forename: Dem-Lion
authors.initials: DL
authors.lastname: Chen
mesh_terms: D000208:Acute Disease; D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology; D002544:Cerebral Infarction / Q000188:drug therapy / Q000209:etiology*; D005334:Fever / Q000209:etiology; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010309:Parotitis / Q000209:etiology
chemical_list: D005343:Fibrinolytic Agents; D001241:Aspirin