title: Alkali metal salts of rutin - Synthesis, spectroscopic (FT-IR, FT-Raman, UV-VIS), antioxidant and antimicrobial studies.
abstract: In this work several metal salts of rutin with lithium, sodium, potassium, rubidium and cesium were synthesized. Their molecular structures were discussed on the basis of spectroscopic (FT-IR, FT-Raman, UV-VIS) studies. Optimized geometrical structure of rutin was calculated by B3LYP/6-311++G(∗∗) method and sodium salt of rutin were calculated by B3LYP/LanL2DZ method. Metal chelation change the biological properties of ligand therefore the antioxidant (FRAP and DPPH) and antimicrobial activities (toward Escherichia coli, Staphylococcus aureus, Enterococcus faecium, Proteus vulgaris, Pseudomonas aeruginosa, Klebsiella pneumonia, Candida albicans and Saccharomyces cerevisiae) of alkali metal salts were evaluated and compared with the biological properties of rutin.
authors.affiliation: Division of Chemistry, Bialystok University of Technology, 29 Zamenhofa Str., 15-435 Bialystok, Poland. Electronic address: m.samsonowicz@pb.edu.pl.
authors.forename: M
authors.initials: M
authors.lastname: Samsonowicz
authors.affiliation: Division of Chemistry, Bialystok University of Technology, 29 Zamenhofa Str., 15-435 Bialystok, Poland.
authors.forename: I
authors.initials: I
authors.lastname: Kamińska
authors.affiliation: Division of Chemistry, Bialystok University of Technology, 29 Zamenhofa Str., 15-435 Bialystok, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Kalinowska
authors.affiliation: Division of Chemistry, Bialystok University of Technology, 29 Zamenhofa Str., 15-435 Bialystok, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Lewandowski
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008672:Metals, Alkali / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D012431:Rutin / Q000737:chemistry / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D008672:Metals, Alkali; D012431:Rutin
keywords: Alkali metal salts; DFT; IR; NMR; Raman; Rutin