title: Two Case Reports and an Updated Review of Spinal Intraosseous Schwannoma.
abstract: We report two rare cases of spinal intraosseous schwannoma (SIS) with sustained myelopathy symptoms and provide an updated review regarding SIS in the literature. A 71-year-old man experienced right lumbocrural pain and gait disturbance accompanied with paresthesia and right leg weakness. Imaging examinations revealed a mass with lesions in L4 vertebral body causing bone destruction and spinal cord compression. Complete resection of the well-demarcated tumor and posterior fusion were performed. A 54-year-old female reported bilateral gait disturbance, paresthesia, and numbness without weakness, and imaging revealed a posterior mass from T9 causing spinal cord compression and bone erosion. The tumor was completely separated from the spinal nerve root. The tumors from both patients were confirmed as schwannomas. Tumor recurrence was not observed at the 2-4 year follow-up. Although rare, SIS should be considered during differential diagnosis and can affect treatment planning. SIS symptoms vary depending on tumor location, and fusion is frequently necessary for spinal reconstruction after complete tumor resection.
authors.affiliation: Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Fan
authors.initials: F
authors.lastname: Zhang
authors.affiliation: Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Feizhou
authors.initials: F
authors.lastname: Lu
authors.affiliation: Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Jianyuan
authors.initials: J
authors.lastname: Jiang
authors.affiliation: Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Hongli
authors.initials: H
authors.lastname: Wang
keywords: Differential diagnosis; Myelopathy; Spinal intraosseous schwannoma