title: Novel RHAG allele encoding the Rh(null) phenotype in Brazil.
abstract: Rhnull is a rare phenotype characterized by the loss of Rh antigen expression. This phenotype can be related to several molecular backgrounds. In this study, we show a novel allele in a Brazilian pregnant woman encoding the Rhnull phenotype due to a change in RHAG exon2 c.310C>T, which leads to a premature stop codon (Gln104Stop).
authors.affiliation: Colsan-Associação Beneficente de Coleta de Sangue, São Paulo, SP, Brazil.
authors.forename: Carine Prisco
authors.initials: CP
authors.lastname: Arnoni
authors.affiliation: Colsan-Associação Beneficente de Coleta de Sangue, São Paulo, SP, Brazil.
authors.forename: Janaína Guilhem
authors.initials: JG
authors.lastname: Muniz
authors.affiliation: Colsan-Associação Beneficente de Coleta de Sangue, São Paulo, SP, Brazil.
authors.forename: Diana
authors.initials: D
authors.lastname: Gazito
authors.affiliation: Colsan-Associação Beneficente de Coleta de Sangue, São Paulo, SP, Brazil.
authors.forename: Rosangela de Medeiros
authors.initials: Rde M
authors.lastname: Person
authors.affiliation: Colsan-Associação Beneficente de Coleta de Sangue, São Paulo, SP, Brazil.
authors.forename: Tatiane Aparecida de Paula
authors.initials: TA
authors.lastname: Vendrame
authors.affiliation: Hemocentro-Unicamp, Campinas, SP, Brazil.
authors.forename: Lilian
authors.initials: L
authors.lastname: Castilho
authors.affiliation: Colsan-Associação Beneficente de Coleta de Sangue, São Paulo, SP, Brazil.
authors.forename: Flavia Roche Moreira
authors.initials: FR
authors.lastname: Latini
mesh_terms: D000483:Alleles; D001798:Blood Proteins / Q000235:genetics*; D001938:Brazil; D018388:Codon, Terminator; D005091:Exons; D005260:Female; D006801:Humans; D008562:Membrane Glycoproteins / Q000235:genetics*; D011247:Pregnancy
chemical_list: D001798:Blood Proteins; D018388:Codon, Terminator; D008562:Membrane Glycoproteins; C498523:RHAG protein, human