title: [Disproportion between placenta weight and birth weight: Physiologic or pathologic].
abstract: OBJECTIVE
  To study risk factors, maternal and neonatal outcome with a high placental weight to birth weight ratio (PW/BW).
  
  
  METHODS
  Two groups of full term singleton pregnancies were created in this single centre retrospective population-based study (a high PW/BW above 0.25 and group control with normal PW/BW between 0.15 and 0.25). Maternal and neonatal outcomes were compared.
  
  
  RESULTS
  Compared with the group with normal PW/BW ratios, the high PW/BW ratio group was associated with increased rates of pre-eclampsia (15.5% versus 1.7%, P<0.05) and small for gestational age (8% versus 0%, P<0.05). Neither maternal risk factors nor neonatal outcome difference were shown after adjusting confounding factors.
  
  
  CONCLUSIONS
  High PW/BW with placentomegaly is associated with increased risk of pre-eclampsia at term underlying a mixture of condition in its pathogenesis.
authors.affiliation: Service de gynécologie-obstétrique, CHU Jean-Verdier, université Paris XIII - Bobigny, avenue du 14-Juillet, 93143 Bondy cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Lorain
authors.affiliation: Service de gynécologie-obstétrique, CHU Jean-Verdier, université Paris XIII - Bobigny, avenue du 14-Juillet, 93143 Bondy cedex, France. Electronic address: jeremy.boujenah@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Boujenah
authors.affiliation: Service de gynécologie-obstétrique, CHU Jean-Verdier, université Paris XIII - Bobigny, avenue du 14-Juillet, 93143 Bondy cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Bricou
authors.affiliation: Service de gynécologie-obstétrique, CHU Jean-Verdier, université Paris XIII - Bobigny, avenue du 14-Juillet, 93143 Bondy cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Benbara
authors.affiliation: Service de gynécologie-obstétrique, CHU Jean-Verdier, université Paris XIII - Bobigny, avenue du 14-Juillet, 93143 Bondy cedex, France.
authors.forename: L
authors.initials: L
authors.lastname: Carbillon
mesh_terms: D000328:Adult; D001724:Birth Weight; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D009929:Organ Size; D010920:Placenta / Q000473:pathology*; D011225:Pre-Eclampsia / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Birth weight; Perinatal; Placenta weight; Placentomegaly; Placentomégalie; Poids de naissance; Poids placentaire; Pre-eclampsia; Pré-éclampsie; Périnatal