title: Erythema multiforme associated with zonisamide in a dog.
abstract: This report describes a dog that developed erythema multiforme in temporal association with administration of the sulphonamide-based anticonvulsant drug zonisamide. Similar adverse drug reactions have been associated with sulphonamide antimicrobial drugs. Caution should be exercised when prescribing this medication for dogs with known hypersensitivity to sulphonamides.
authors.affiliation: Department of Small Animal Clinical Sciences, University of Tennessee, 2407 River Drive, Knoxville, TN, 37996, USA.
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Ackermann
authors.affiliation: Department of Small Animal Clinical Sciences, University of Tennessee, 2407 River Drive, Knoxville, TN, 37996, USA.
authors.forename: Linda A
authors.initials: LA
authors.lastname: Frank
authors.affiliation: Department of Biomedical and Diagnostic Sciences, University of Tennessee, 2407 River Drive, Knoxville, TN, 37996, USA.
authors.forename: Michael F
authors.initials: MF
authors.lastname: McEntee
authors.affiliation: Department of Small Animal Clinical Sciences, University of Tennessee, 2407 River Drive, Knoxville, TN, 37996, USA.
authors.forename: Elizabeth R
authors.initials: ER
authors.lastname: May
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000009:adverse effects*; D004283:Dog Diseases / Q000139:chemically induced* / Q000473:pathology; D004285:Dogs; D004827:Epilepsy / Q000188:drug therapy / Q000662:veterinary; D004892:Erythema Multiforme / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D007555:Isoxazoles / Q000009:adverse effects*; D008297:Male; D012867:Skin / Q000473:pathology; D000078305:Zonisamide
chemical_list: D000927:Anticonvulsants; D007555:Isoxazoles; D000078305:Zonisamide