title: Prospective repair of Ventral Hernia Working Group type 3 and 4 abdominal wall defects with condensed polytetrafluoroethylene (MotifMESH) mesh.
abstract: BACKGROUND
  Treatment of clean-contaminated and contaminated ventral hernia defects remains controversial. Newer prosthetic materials may play an important role in these patients.
  
  
  METHODS
  Ten patients with Ventral Hernia Working Group types 3 and 4 were prospectively enrolled and subsequently treated with direct supported repairs with condensed fenestrated polytetrafluoroethylene mesh. The primary outcome was hernia occurrence at 1 year after surgery. Secondary outcomes included surgical site infection, surgical site occurrence, medical complications, pain, and other patient-reported outcomes.
  
  
  RESULTS
  There were no immediate postoperative infections and one minor postoperative hematoma treated in the office. One patient required delayed mesh removal 9 months after placement. Importantly, the mesh removal procedure was straightforward because of the material properties of the mesh. Of the 9 patients still with mesh, there were no hernia recurrences at the repair site with one full year of follow-up.
  
  
  CONCLUSIONS
  Contaminated and clean-contaminated abdominal wall defects can be effectively and durably treated with condensed polytetrafluoroethylene mesh.
authors.affiliation: Division of Plastic Surgery, Department of Surgery, Northwestern Feinberg School of Medicine, Chicago, IL, USA.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Cheesborough
authors.affiliation: Division of Plastic Surgery, Department of Surgery, Northwestern Feinberg School of Medicine, Chicago, IL, USA.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.affiliation: Division of Plastic Surgery, Department of Surgery, Northwestern Feinberg School of Medicine, Chicago, IL, USA.
authors.forename: Derek
authors.initials: D
authors.lastname: Hsu
authors.affiliation: Division of Plastic Surgery, Department of Surgery, Northwestern Feinberg School of Medicine, Chicago, IL, USA. Electronic address: gdumania@nmh.org.
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Dumanian
mesh_terms: D034861:Abdominal Wall / Q000601:surgery; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006555:Hernia, Ventral / Q000601:surgery*; D059685:Herniorrhaphy / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011446:Prospective Studies; D012008:Recurrence; D013526:Surgical Mesh; D013530:Surgical Wound Infection; D016896:Treatment Outcome
chemical_list: D011138:Polytetrafluoroethylene
keywords: Mesh; Surgical site infection; Surgical site occurrence; Ventral hernia