title: A Facile FeCl3/I2-Catalyzed Aerobic Oxidative Coupling Reaction: Synthesis of Tetrasubstituted Imidazoles from Amidines and Chalcones.
abstract: A facile and efficient route for the synthesis of tetrasubstituted imidazoles from amidines and chalcones via FeCl3/I2-catalyzed aerobic oxidative coupling has been developed. This new strategy is featured by high regioselectivity and yields, good functional group tolerance, and mild reaction conditions.
authors.forename: Yuelu
authors.initials: Y
authors.lastname: Zhu
authors.forename: Cheng
authors.initials: C
authors.lastname: Li
authors.forename: Jidong
authors.initials: J
authors.lastname: Zhang
authors.forename: Mengyao
authors.initials: M
authors.lastname: She
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.affiliation: ‡Xi'an Catalyst Chemical Co., Ltd., Xi'an Shaanxi 710016, P. R. China.
authors.forename: Kerou
authors.initials: K
authors.lastname: Wan
authors.forename: Yaqi
authors.initials: Y
authors.lastname: Wang
authors.forename: Bin
authors.initials: B
authors.lastname: Yin
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.forename: Jianli
authors.initials: J
authors.lastname: Li
mesh_terms: D000578:Amidines / Q000737:chemistry*; D002384:Catalysis; D047188:Chalcones / Q000737:chemistry*; D002712:Chlorides / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D058451:Oxidative Coupling
chemical_list: D000578:Amidines; D047188:Chalcones; D002712:Chlorides; D005290:Ferric Compounds; D007093:Imidazoles; D007455:Iodine; C024555:ferric chloride