title: A case of acute psychosis in a patient following exposure to a single high dose of styrene.
abstract: We report a case of acute psychotic symptoms following exposure to a single high dose of styrene monomer. The 24-year-old male patient showed psychotic and cognitive symptoms immediately after exposure. His psychotic symptoms included auditory hallucinations and delusions of reference. Brain magnetic resonance imaging, electroencephalography, and laboratory examinations were performed to evaluate any other causes. The clinical, neuroimaging, and laboratory review in this case suggested that the suddenly developed psychotic symptoms that led to chronic deterioration were caused by the single exposure to styrene monomer. This is the first recent report in which acute psychotic symptoms developed from a single high dose of styrene suffocation compared with previous findings showing symptoms because of long-term low-dose exposure.
authors.affiliation: Department of Psychiatry, Pusan National University Hospital, Busan, Republic of Korea.|Department of Psychiatry, Pusan National University College of Medicine, Kyungnam, Republic of Korea.|Medical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
authors.forename: Eunsoo
authors.initials: E
authors.lastname: Moon
authors.affiliation: Department of Psychiatry, Pusan National University Hospital, Busan, Republic of Korea.|Department of Psychiatry, Pusan National University College of Medicine, Kyungnam, Republic of Korea.|Medical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
authors.forename: Hwagyu
authors.initials: H
authors.lastname: Suh
authors.affiliation: Department of Psychiatry, Pusan National University Hospital, Busan, Republic of Korea.|Department of Psychiatry, Pusan National University College of Medicine, Kyungnam, Republic of Korea.|Medical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
authors.forename: Byung Dae
authors.initials: BD
authors.lastname: Lee
authors.affiliation: Department of Psychiatry, Pusan National University Hospital, Busan, Republic of Korea.|Department of Psychiatry, Pusan National University College of Medicine, Kyungnam, Republic of Korea.|Medical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
authors.forename: Je Min
authors.initials: JM
authors.lastname: Park
authors.affiliation: Department of Psychiatry, Pusan National University Hospital, Busan, Republic of Korea.|Department of Psychiatry, Pusan National University College of Medicine, Kyungnam, Republic of Korea.|Medical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
authors.forename: Young Min
authors.initials: YM
authors.lastname: Lee
authors.affiliation: Department of Psychiatry, Pusan National University Hospital, Busan, Republic of Korea.|Department of Psychiatry, Pusan National University College of Medicine, Kyungnam, Republic of Korea.|Medical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
authors.forename: Hee Jeong
authors.initials: HJ
authors.lastname: Jeong
mesh_terms: D000208:Acute Disease; D014150:Antipsychotic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects*; D011605:Psychoses, Substance-Induced / Q000188:drug therapy / Q000209:etiology*; D000069348:Quetiapine Fumarate / Q000627:therapeutic use; D020058:Styrene / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents; D000069348:Quetiapine Fumarate; D020058:Styrene
keywords: delusion; exposure; hallucination; psychosis; styrene