title: A clinical study on the Naimittika Rasayana effect of Silajatu and Mamajjaka in type-2 Diabetes Mellitus.
abstract: BACKGROUND
  Recent years have shown an alarming rise in the incidence of diabetes mellitus (DM) all over the world. The present management of DM it not satisfactory. Hence, alternative systems of medicine are also being explored. Prameha as described in Ayurveda is a disease synonymous with today's DM. The patients of Prameha inherently carry the risk of impaired Agni and depleted Ojas status, that is, hypometabolic and immuno-compromised state. Now the primary goal is not merely to achieve normoglycemia, but also to minimize its complications. In this context, many Ayurvedic drugs are undergoing extensive research.
  
  
  OBJECTIVE
  To evaluate the anti-diabetic, immune-enhancer and biofire balancing effects of Naimittika Rasayana drugs viz. Silajatu and Mamajjaka in type-2 DM.
  
  
  METHODS
  A total of 95 patients of type-2 DM were registered; in which 84 patients turned up for full follow-up. Patients were randomly allocated into three groups; Group-A was treated with Mamajjaka (500mg twice a day) and Group-B with Silajatu (500mg twice a day) and Group-C was treated with modern drug and assessment was done at monthly intervals for three months.
  
  
  RESULTS
  The selected Rasayana drugs have shown good response on subjective and objective parameters. The Mamajjaka treated patients responded better. However, as regards the reduction of post prandial blood sugar, Silajatu was superior.
  
  
  CONCLUSIONS
  The Ayurveda-inspired holistic approach seems to have a unique response promoting Agni (biofire) and Ojas (immune strength) status leading to good health and wellness.
authors.affiliation: Department of Kayachikitsa, Faculty of Ayurveda, Banaras Hindu University, Varanasi, India.
authors.forename: Sanjai
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Division of Biostatistics, Department of Community Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
authors.forename: Girish
authors.initials: G
authors.lastname: Singh
authors.affiliation: Department of Kayachikitsa, Faculty of Ayurveda, Banaras Hindu University, Varanasi, India.
authors.forename: Ajai Kumar
authors.initials: AK
authors.lastname: Pandey
authors.affiliation: Department of Kayachikitsa, Faculty of Ayurveda, Banaras Hindu University, Varanasi, India.
authors.forename: Ram Harsh
authors.initials: RH
authors.lastname: Singh
keywords: Agni; Madhumeha; Mamajjaka; Ojas; Rasayana; Silajatu; diabetes mellitus