title: A case of gastric adenocarcinoma arising from a fundic gland polyp.
abstract: A rare case of gastric adenocarcinoma arising on the surface of a fundic gland polyp is reported. A 36-year-old Japanese woman was referred to our hospital for examination and treatment of a polyp that had been detected in another hospital. She did not have a history of familial adenomatous polyposis (FAP). Endoscopic examination revealed a 10-mm-diameter fundic gland polyp in the body of the stomach. The polyp had an irregular depression on its top, suggesting the presence of malignancy. Endoscopic mucosal resection was done to make a histological diagnosis. This revealed a fundic gland polyp with a tiny superficial adenocarcinoma. Atrophic changes of the gastric mucosa were mild, although Helicobacter pylori infection was positive. It is suggested that fundic gland polyps have the potential for malignant transformation.
authors.affiliation: Department of Internal Medicine, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Rie
authors.initials: R
authors.lastname: Kawase
authors.affiliation: Department of Endoscopy, Asa-City Hospital, 2-1-1, Kabeminami, Asakita-ku, Hiroshima, Japan. s-nagata@asa-hosp.city.hiroshima.jp.
authors.forename: Shinji
authors.initials: S
authors.lastname: Nagata
authors.affiliation: Department of Internal Medicine, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Mieko
authors.initials: M
authors.lastname: Onoyama
authors.affiliation: Department of Internal Medicine, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Nana
authors.initials: N
authors.lastname: Nakayama
authors.affiliation: Department of Internal Medicine, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Yohji
authors.initials: Y
authors.lastname: Honda
authors.affiliation: Department of Internal Medicine, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kuwahara
authors.affiliation: Department of Internal Medicine, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kimura
authors.affiliation: Department of Internal Medicine, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Tsuji
authors.affiliation: Department of Endoscopy, Asa-City Hospital, 2-1-1, Kabeminami, Asakita-ku, Hiroshima, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ohgoshi
authors.affiliation: Department of Pathology, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Sakatani
authors.affiliation: Department of Pathology, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Mayumi
authors.initials: M
authors.lastname: Kaneko
authors.affiliation: Department of Molecular Medicine and Science, Hiroshima University, Hiroshima, Japan.
authors.forename: Masanori
authors.initials: M
authors.lastname: Ito
authors.affiliation: Faculty of Human Culture and Science, Prefectural University, Hiroshima, Japan.
authors.forename: Fumio
authors.initials: F
authors.lastname: Shimamoto
authors.affiliation: Department of Internal Medicine, Asa-City Hospital, Hiroshima, Japan.
authors.forename: Tohru
authors.initials: T
authors.lastname: Hidaka
keywords: Adenocarcinoma; Fundic gland polyp; Helicobacter pylori