title: Antifouling Compounds from the Marine-Derived Fungus Aspergillus terreus SCSGAF0162.
abstract: A new cyclic tetrapeptide, asperterrestide B (1), and 11 known compounds (2-12) were isolated from a marine-derived fungus Aspergillus terreus SCSGAF0162. The structure of 1 was elucidated by spectroscopic analysis, and the absolute configuration of 1 was determined by Mosher ester and Marfey's methods. Compounds 4, 6, and 8 had potent antifouling activity against larvae of the barnacle Balanus amphitrite, with EC50 values of 17.1 ± 1.2, 11.6 ± 0.6, and 17.1 ± 0.8 μg x mL(-1), respectively.
authors.forename: Xu-Hua
authors.initials: XH
authors.lastname: Nong
authors.forename: Xiao-Yong
authors.initials: XY
authors.lastname: Zhang
authors.forename: Xin-Ya
authors.initials: XY
authors.lastname: Xu
authors.forename: Shu-Hua
authors.initials: SH
authors.lastname: Qi
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000382:microbiology*; D001230:Aspergillus / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism; D057219:Biofouling / Q000517:prevention & control*; D001685:Biological Factors / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*; D002681:China; D007814:Larva / Q000187:drug effects / Q000502:physiology; D015394:Molecular Structure; D012623:Seawater / Q000382:microbiology*; D001468:Thoracica / Q000187:drug effects / Q000502:physiology*
chemical_list: D001685:Biological Factors