title: Rhabdomyolysis and acute kidney injury in dengue fever.
abstract: Rhabdomyolysis is a rare but potentially lethal complication of severe dengue fever. We present a case of 21-year-old man with fever, bodyache and black coloured and decreasing amount of urine. He was positive for NS1 (non-structural protein-1) antigen and IgM antibody for dengue. Platelet count was below 20 × 10(9)/L and kidney function test was deranged. Urine was positive for myoglobin. The patient was managed emergently on conservative lines and improved in 10 days. Rhabdomyolysis should always be kept in mind in a patient with severe dengue, as its early detection and prompt management can prevent further progression to acute renal failure.
authors.affiliation: Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Arvind
authors.initials: A
authors.lastname: Mishra
authors.affiliation: Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Varun Kumar
authors.initials: VK
authors.lastname: Singh
authors.affiliation: Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Satyan
authors.initials: S
authors.lastname: Nanda
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000914:Antibodies, Viral / Q000097:blood; D006801:Humans; D008297:Male; D009212:Myoglobinuria; D010976:Platelet Count; D012206:Rhabdomyolysis / Q000209:etiology*; D019595:Severe Dengue / Q000150:complications*; D017361:Viral Nonstructural Proteins / Q000097:blood; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; C082515:NS1 protein, dengue-1 virus; D017361:Viral Nonstructural Proteins