title: Arboridinine, a Pentacyclic Indole Alkaloid with a New Cage Carbon-Nitrogen Skeleton Derived from a Pericine Precursor.
abstract: A new monoterpene indole alkaloid characterized by an unprecedented pentacyclic cage skeleton, arboridinine (1), was isolated from a Malaysian Kopsia species. The structure and absolute configuration of the alkaloid were determined based on NMR, MS, and X-ray diffraction analysis. A possible biogenetic pathway from a pericine precursor is presented.
authors.affiliation: †Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
authors.forename: Suet-Pick
authors.initials: SP
authors.lastname: Wong
authors.affiliation: ‡University Malaysia of Computer Science and Engineering, Jalan Alamanda 2, Precint 1, 62000 Putrajaya, Malaysia.
authors.forename: Chew-Yan
authors.initials: CY
authors.lastname: Gan
authors.forename: Kuan-Hon
authors.initials: KH
authors.lastname: Lim
authors.forename: Kang-Nee
authors.initials: KN
authors.lastname: Ting
authors.affiliation: †Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
authors.forename: Yun-Yee
authors.initials: YY
authors.lastname: Low
authors.affiliation: †Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.
authors.forename: Toh-Seok
authors.initials: TS
authors.lastname: Kam
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D008296:Malaysia; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D000470:Alkaloids; D026121:Indole Alkaloids; D011083:Polycyclic Compounds; C000602347:arboridinine; C037128:pericine