title: Perspective: The Alzheimer's Disease Neuroimaging Initiative and the role and contributions of the Private Partner Scientific Board (PPSB).
abstract: The Alzheimer's Disease Neuroimaging Initiative (ADNI) Private Partner Scientific Board (PPSB) is comprised of representatives of private, for-profit entities (including pharmaceutical, biotechnology, diagnostics, imaging companies, and imaging contract research organizations), and nonprofit organizations that provide financial and scientific support to ADNI through the Foundation for the National Institutes of Health. The PPSB serves as an independent, open, and precompetitive forum in which all private sector and not-for-profit partners in ADNI can collaborate, share information, and offer scientific and private-sector perspectives and expertise on issues relating to the ADNI project. In this article, we review and highlight the role, activities, and contributions of the PPSB within the ADNI project, and provide a perspective on remaining unmet needs and future directions.
authors.affiliation: Neuroscience Biomarkers, Discovery, Janssen Research and Development, San Diego, CA, USA. Electronic address: eliu12@its.jnj.com.
authors.forename: Enchi
authors.initials: E
authors.lastname: Liu
authors.affiliation: Neuroscience Clinical Development, Clinical Neuroscience Eisai, Woodcliff Lake, NJ, USA.
authors.forename: Johan
authors.initials: J
authors.lastname: Luthman
authors.affiliation: Clinical Development, Biogen, Cambridge, MA, USA.
authors.forename: Jesse M
authors.initials: JM
authors.lastname: Cedarbaum
authors.affiliation: Experimental Medicine, Janssen Pharmaceutica NV, Beerse, Belgium.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Schmidt
authors.affiliation: Clinical and Translational Science, Imaging, Takeda Pharmaceuticals, Inc, Deerfield, IL, USA.
authors.forename: Patricia E
authors.initials: PE
authors.lastname: Cole
authors.affiliation: Medical and Scientific Relations, Alzheimer's Association, Chicago, IL, USA.
authors.forename: James
authors.initials: J
authors.lastname: Hendrix
authors.affiliation: Medical and Scientific Relations, Alzheimer's Association, Chicago, IL, USA.
authors.forename: Maria C
authors.initials: MC
authors.lastname: Carrillo
authors.affiliation: Foundation for the NIH, Bethesda, MD, USA.
authors.forename: Dorothy
authors.initials: D
authors.lastname: Jones-Davis
authors.affiliation: Foundation for the NIH, Bethesda, MD, USA.
authors.forename: Erika
authors.initials: E
authors.lastname: Tarver
authors.affiliation: Neuroscience Clinical Development, Janssen Research and Development, Titusville, NJ, USA.
authors.forename: Gerald
authors.initials: G
authors.lastname: Novak
authors.affiliation: Medical Affairs, Piramal Pharma Inc, Boston, MA, USA.
authors.forename: Susan
authors.initials: S
authors.lastname: De Santi
authors.affiliation: Clinical Biomarkers, Bristol-Meyer Squibb, Hopewell, NJ, USA.
authors.forename: Holly D
authors.initials: HD
authors.lastname: Soares
authors.affiliation: Office of the Director, National Institute of Mental Health, Rockville, MD, USA.
authors.forename: William Z
authors.initials: WZ
authors.lastname: Potter
authors.affiliation: Biomedicines Business Unit, Alzheimer's Disease Platform Team, Eli Lilly and Company, Indianapolis, IN, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Siemers
authors.affiliation: Tailored Therapeutics, Eli Lilly and company, Indianapolis, IN, USA.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Schwarz
mesh_terms: D000544:Alzheimer Disease / Q000150:complications / Q000175:diagnosis*; D001709:Biotechnology; D003072:Cognition Disorders / Q000209:etiology; D003253:Consultants; D004345:Drug Industry; D006801:Humans; D059906:Neuroimaging / Q000379:methods*; D055818:Public-Private Sector Partnerships; D014481:United States
keywords: ADNI; Alzheimer's Disease Neuroimaging Initiative; FNIH; Foundation for the National Institutes of Health; PPSB; Pharmaceutical industry; Private Partner Scientific Board