title: Design and optimization of the fixing plate for customized mandible implants.
abstract: Customized mandible implants are used as the most effective surgical option for the reconstruction of the mandible after resection, and have become more prevalent, especially with the development of reverse engineering and rapid prototyping (RP). The fixing plate is the most important and complicated part; however, improper structures of the fixing plate often cost unnecessary workloads during surgery and might lead to fracture failure eventually. The fillet radius, cross-section, and countersinks distribution of the fixing plate are the three most significant factors to affect the strength of the implant. The fillet radius on the plate-body transition determines the amount of grinding bone and can also affect the strength of the fixing plate. In addition, both the different cross-sections of the fixing plate and the different distributions of the countersinks can influence the strength and anti-bending capacity of the fixing plate. Various structures of the fixing plate have been designed, and theoretical calculations and finite element analysis on its strength have been conducted in this study, and results presented an optimized design of the structure of the fixing plate. Moreover, for validation purposes, several clinical applications were successfully implemented with the optimized structure.
authors.affiliation: State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an 710054, PR China.
authors.forename: Mian
authors.initials: M
authors.lastname: Qin
authors.affiliation: State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an 710054, PR China. Electronic address: yaxiongliu@mail.xjtu.edu.cn.
authors.forename: Yaxiong
authors.initials: Y
authors.lastname: Liu
authors.affiliation: State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an 710054, PR China. Electronic address: menlwang@mail.xjtu.edu.cn.
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.affiliation: State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an 710054, PR China.
authors.forename: Jiankang
authors.initials: J
authors.lastname: He
authors.affiliation: State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China.
authors.forename: Ming
authors.initials: M
authors.lastname: Xuan
authors.affiliation: State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China.
authors.forename: Chengge
authors.initials: C
authors.lastname: Hua
authors.affiliation: State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an 710054, PR China.
authors.forename: Dichen
authors.initials: D
authors.lastname: Li
authors.affiliation: State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an 710054, PR China; Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, LS29JT, UK.
authors.forename: Zhongmin
authors.initials: Z
authors.lastname: Jin
authors.affiliation: State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, PR China.
authors.forename: Xiaoyi
authors.initials: X
authors.lastname: Wang
mesh_terms: D001860:Bone Plates; D020342:Finite Element Analysis; D006801:Humans; D008334:Mandible / Q000601:surgery*; D011474:Prosthesis Design / Q000379:methods*
keywords: Customized mandible implant; Finite element analysis; Fixing plate