title: Regiospecific Intermolecular Aminohydroxylation of Olefins by Photoredox Catalysis.
abstract: A simple and regiospecific aminohydroxylation of olefins by photoredox catalysis has been developed. N-protected 1-aminopyridinium salts are the key compounds and serve as amidyl radical precursors by the action of Ir photocatalysts, fac-[Ir(ppy)3] and [Ir(ppy)2 (dtbbpy)](PF6) (ppy=2-pyridylphenyl, dtbbpy=4,4'-di-tert-butyl-2,2'-bipyridine). The present photocatalytic system allows for synthesis of vicinal aminoalcohol derivatives from olefins with various functional groups under mild reaction conditions with easy handling.
authors.affiliation: Chemical Resources Laboratory, Tokyo Institute of Technology, R1-27, 4259 Nagatsuta, Midori-ku, Yokohama 226-8503 (Japan).
authors.forename: Kazuki
authors.initials: K
authors.lastname: Miyazawa
authors.affiliation: Chemical Resources Laboratory, Tokyo Institute of Technology, R1-27, 4259 Nagatsuta, Midori-ku, Yokohama 226-8503 (Japan). koike.t.ad@m.titech.ac.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Koike
authors.affiliation: Chemical Resources Laboratory, Tokyo Institute of Technology, R1-27, 4259 Nagatsuta, Midori-ku, Yokohama 226-8503 (Japan). makita@res.titech.ac.jp.
authors.forename: Munetaka
authors.initials: M
authors.lastname: Akita
keywords: amination; carbocations; electron transfer; homogeneous catalysis; photochemistry