title: Increased pressure alters plasma membrane dynamics and renders acute myeloid leukemia cells resistant to daunorubicin.
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, Toronto, ON.
authors.forename: Victor Sanjit
authors.initials: VS
authors.lastname: Nirmalanandhan
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, Toronto, ON.
authors.forename: Rose
authors.initials: R
authors.lastname: Hurren
authors.affiliation: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
authors.forename: William D
authors.initials: WD
authors.lastname: Cameron
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, Toronto, ON.
authors.forename: Marcela
authors.initials: M
authors.lastname: Gronda
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, Toronto, ON.
authors.forename: Aisha
authors.initials: A
authors.lastname: Shamas-Din
authors.affiliation: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
authors.forename: Lidan
authors.initials: L
authors.lastname: You
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, Toronto, ON.
authors.forename: Mark D
authors.initials: MD
authors.lastname: Minden
authors.affiliation: Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada Toronto General Research Institute, University Health Network, Toronto, ON, Canada.
authors.forename: Jonathan V
authors.initials: JV
authors.lastname: Rocheleau
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, Toronto, ON aaron.schimmer@utoronto.ca.
authors.forename: Aaron D
authors.initials: AD
authors.lastname: Schimmer
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000378:metabolism*; D002470:Cell Survival / Q000187:drug effects; D003630:Daunorubicin / Q000494:pharmacology*; D019008:Drug Resistance, Neoplasm; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000378:metabolism; D055548:Vapor Pressure
chemical_list: D000903:Antibiotics, Antineoplastic; D003630:Daunorubicin
keywords: chemosensitivity; leukemia; membrane dynamics; pressure