title: The Importance of the 5-Alkyl Substituent for the Violet Smell of Ionones: Synthesis of Racemic 5-Demethyl-α-ionone.
abstract: The synthesis and the odor tonalities of racemic 5-demethyl-α-ionone are described. This synthetic ionone derivative did not show the typical floral-woody violet smell of α-ionone, definitely proving the importance of a suitably sized and spatially oriented alkyl substituent at C(5) for stimulating olfactory receptors of ionones.
authors.forename: Serena
authors.initials: S
authors.lastname: Chierici
authors.forename: Serena
authors.initials: S
authors.lastname: Bugoni
authors.forename: Alessio
authors.initials: A
authors.lastname: Porta
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Zanoni
authors.forename: Giovanni
authors.initials: G
authors.lastname: Vidari
mesh_terms: D015394:Molecular Structure; D045792:Norisoprenoids / Q000138:chemical synthesis* / Q000737:chemistry; D009812:Odorants / Q000032:analysis; D012903:Smell; D013237:Stereoisomerism; D032413:Viola / Q000737:chemistry*
chemical_list: D045792:Norisoprenoids; C011879:alpha-ionone