title: Recent advances in electrochemical biosensors based on graphene two-dimensional nanomaterials.
abstract: Graphene as a star among two-dimensional nanomaterials has attracted tremendous research interest in the field of electrochemistry due to their intrinsic properties, including the electronic, optical, and mechanical properties associated with their planar structure. The marriage of graphene and electrochemical biosensors has created many ingenious biosensing strategies for applications in the areas of clinical diagnosis and food safety. This review provides a comprehensive overview of the recent advances in the development of graphene based electrochemical biosensors. Special attention is paid to graphene-based enzyme biosensors, immunosensors, and DNA biosensors. Future perspectives on high-performance graphene-based electrochemical biosensors are also discussed.
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, PR China; Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States.
authors.forename: Yang
authors.initials: Y
authors.lastname: Song
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, PR China; Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States.
authors.forename: Yanan
authors.initials: Y
authors.lastname: Luo
authors.affiliation: Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States.
authors.forename: Chengzhou
authors.initials: C
authors.lastname: Zhu
authors.affiliation: Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States.
authors.forename: He
authors.initials: H
authors.lastname: Li
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, PR China; Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States; Paul G. Allen School for Global Animal Health, Washington State University, Pullman, WA 99164, United States. Electronic address: dan.du@mail.ccnu.edu.cn.
authors.forename: Dan
authors.initials: D
authors.lastname: Du
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, PR China; Department of Mechanical and Material Engineering, Washington State University, Pullman, WA 99164, United States; Paul G. Allen School for Global Animal Health, Washington State University, Pullman, WA 99164, United States. Electronic address: yuehe.lin@wsu.edu.
authors.forename: Yuehe
authors.initials: Y
authors.lastname: Lin
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry; D004563:Electrochemistry / Q000379:methods*; D004798:Enzymes / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D004798:Enzymes; D006108:Graphite; D004247:DNA
keywords: DNA sensors; Electrochemical biosensor; Enzyme-based biosensors; Graphene; Immunosensors; Two-dimensional nanomaterials