title: Angiosarcoma involving colon and bone successfully responded to paclitaxel and zoledronate: case report.
abstract: Angiosarcoma involving the gastrointestinal tract is extremely rare. We present a case of multifocal angiosarcoma involving the colon and bone. A 73-year-old male presented with anemia and pain in the left supra-iliac lesion. Colonoscopy revealed multiple hemorrhagic-appearance tumors. Computed tomography scan showed masses in the sigmoid colon and bone. A left-sided colectomy was performed to prevent bleeding from the tumor. The histopathological diagnosis was angiosarcoma of multiple sites of the colon. We chose a combination of paclitaxel and zoledronate as the chemotherapy regimen. After surgery, bone lesions were diminished by chemotherapy and showed no uptake on (18)F-fluorodeoxyglucose-positron emission tomography. The patient survived for 38 months after surgery.
authors.affiliation: Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Matsuda
authors.affiliation: Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
authors.forename: Katsunari
authors.initials: K
authors.lastname: Takifuji
authors.affiliation: Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Hotta
authors.affiliation: Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
authors.forename: Shozo
authors.initials: S
authors.lastname: Yokoyama
authors.affiliation: Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan.
authors.forename: Junji
authors.initials: J
authors.lastname: Ieda
authors.affiliation: Second Department of Internal Medicine, School of Medicine, Wakayama Medical University, Wakayama, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Arii
authors.affiliation: Second Department of Internal Medicine, School of Medicine, Wakayama Medical University, Wakayama, Japan.
authors.forename: Masao
authors.initials: M
authors.lastname: Ichinose
authors.affiliation: Department of Clinical Laboratory Medicine, School of Medicine, Wakayama Medical University, Wakayama, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Nakamura
authors.affiliation: Department of Clinical Laboratory Medicine, School of Medicine, Wakayama Medical University, Wakayama, Japan.
authors.forename: Hironao
authors.initials: H
authors.lastname: Yasuoka
authors.affiliation: Second Department of Surgery, School of Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8510, Japan. yamaue-h@wakayama-med.ac.jp.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Yamaue
keywords: Angiosarcoma; Colonic involvement; FDG-PET; Paclitaxel; Zoledronate