title: Delineating cancer evolution with single-cell sequencing.
abstract: Single-cell sequencing methods are revolutionizing cancer research and medicine by providing powerful tools to investigate intratumor heterogeneity and rare subpopulations.
authors.affiliation: Department of Genetics, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA. Department of Bioinformatics and Computational Biology, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA. Graduate Program in Genes and Development, Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA. nnavin@mdanderson.org.
authors.forename: Nicholas E
authors.initials: NE
authors.lastname: Navin
mesh_terms: D001943:Breast Neoplasms / Q000235:genetics* / Q000473:pathology*; D056915:DNA Copy Number Variations; D018450:Disease Progression; D005260:Female; D018628:Gene Dosage; D018740:Genetic Heterogeneity; D023281:Genomics; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D006801:Humans; D009154:Mutation; D010641:Phenotype; D017422:Sequence Analysis, DNA; D059010:Single-Cell Analysis; D057170:Translational Research, Biomedical