title: PREDICTION OF PESTICIDE RISKS TO HUMAN HEALTH BY DRINKING WATER EXTRACTED FROM UNDERGROUND SOURCES.
abstract: The aim of our work was to develop the method of prediction of the risk of contamination of groundwater with different classes' fungicides in soil and climatic conditions of Ukraine and other European countries, as well as hygienic assessment of their impact on public health. The calculation and comparative evaluation of various indices of pesticides migration into groundwater were conducted. It was established that the most optimal and complete is an LEACN index according to which in soil and climatic conditions of Ukraine the risk of contamination of ground and surface water by all studied fungicides is low, except penconazole and tebuconazole for which there is medium contamination risk. We have developed a method of integrated assessment of the potential hazard of pesticide exposure on the human organism when it enters ground and surface waters, which are intensive used for drinking water supplying. Integral index of this method - IGCHI - is obtained by adding of scores assigned to main indicators characterizing the danger to humans in pesticides gets into the water: index of leaching (LEACН), half life period in water (DT50) and the allowable daily intake (ADI). According developed method all studied fungicides are low hazard for human, except benalaxy-M and tebuconazole which are hazard and highly hazard, respectively. It was established that, benalaxy-M is hazard when it leached into groundwater and surface water, tebuconazole is highly hazard, which is primarily due to their high stability in water (in both cases) and significant potential for leaching (in the latter case).
authors.affiliation: O.O. Bogomolets National Medical University, Hygiene and Ecology Institute, Kyiv, Ukraine.
authors.forename: A
authors.initials: A
authors.lastname: Antonenko
authors.affiliation: O.O. Bogomolets National Medical University, Hygiene and Ecology Institute, Kyiv, Ukraine.
authors.forename: O
authors.initials: O
authors.lastname: Vavrinevych
authors.affiliation: O.O. Bogomolets National Medical University, Hygiene and Ecology Institute, Kyiv, Ukraine.
authors.forename: S
authors.initials: S
authors.lastname: Omelchuk
authors.affiliation: O.O. Bogomolets National Medical University, Hygiene and Ecology Institute, Kyiv, Ukraine.
authors.forename: M
authors.initials: M
authors.lastname: Korshun
mesh_terms: D060766:Drinking Water / Q000009:adverse effects* / Q000737:chemistry; D004784:Environmental Monitoring; D005060:Europe; D060587:Groundwater / Q000737:chemistry; D006801:Humans; D010575:Pesticides / Q000737:chemistry / Q000633:toxicity*; D014455:Ukraine; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D060766:Drinking Water; D010575:Pesticides; D014874:Water Pollutants, Chemical