title: A Rare Human Case of Dirofilaria repens Infection in the Subcutaneous Posterior Thorax with Molecular Identification.
abstract: The emergence of Dirofilarial infections in Asia including Vietnam is a clinically significant threat to the community. We here report a rare case of subcutaneous Dirofilaria repens infection on the posterior thoracic wall in a young woman presenting a painful, itchy, and palpable nodule. The adult worm was identified by mitochondrial cox1 and nuclear ITS-2 sequence determination. The diagnosis was additionally confirmed by 16S rRNA sequencing of the endosymbiont Wolbachia pipientis commonly co-existing with D. repens. This is a rare case of subcutaneous human infection on the posterior thoracic region caused by D. repens.
authors.affiliation: Department of Parasitology, Vietnam Military Medical University, Hanoi, Vietnam.
authors.forename: Tran Anh
authors.initials: TA
authors.lastname: Le
authors.affiliation: Department of Pathology, Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.
authors.forename: Thuat Thang
authors.initials: TT
authors.lastname: Vi
authors.affiliation: Department of Parasitology, Vietnam Military Medical University, Hanoi, Vietnam.
authors.forename: Khac Luc
authors.initials: KL
authors.lastname: Nguyen
authors.affiliation: Immunology Department, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
authors.forename: Thanh Hoa
authors.initials: TH
authors.lastname: Le
mesh_terms: D000328:Adult; D000818:Animals; D060348:Dirofilaria repens / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D004184:Dirofilariasis / Q000175:diagnosis / Q000469:parasitology*; D005260:Female; D006801:Humans; D010802:Phylogeny; D013909:Thorax / Q000469:parasitology*
keywords: Dirofilaria repens; molecular identification; subcutaneous Dirofilariasis