title: [Glomus tumour of the lung: a case report and literature review].
abstract: BACKGROUND
  Glomus tumours are neoplasms arising from cells of the neuromyoarterial glomus bodies, which almost always occur in a subungual location. A lung location is extremely rare, with few cases reported in the literature.
  
  
  METHODS
  The case is presented of a 33 year-old male, with non-productive cough, dyspnoea at rest, intermittent fever, and mild pain in rib cage. A chest radiograph showed a consolidation in the left lung, and computed tomography revealed a lesion in the hilum that extended to the bronchus of the lingula obstructing, and causing post-obstructive pneumonia. A biopsy was obtained by rigid bronchoscopy biopsy, which showed a well circumscribed tumour constituted by intermediate-sized cells, and abundant cytoplasm that are arranged in a pattern surrounding numerous thin-walled blood vessels, with no pleomorphism, significant mitotic activity or necrosis. Immunohistochemistry revealed diffuse positivity with smooth muscle actin, vimentin, caldesmon; focal reactivity with desmin and CD117, CD34 highlights the vascular pattern. Ki67 proliferation rate was 1%. Synaptophysin, EMA and cytokeratin cocktail were negative, making the diagnosis of glomus tumour.
  
  
  CONCLUSIONS
  Glomus tumours are rare neoplasms that usually appear in the dermis and subcutaneous tissue, where it is common to find glomus bodies. Occasionally glomus tumours can occur in extra-cutaneous sites such as the gastrointestinal tract, bone and respiratory system, with this case being a new case of rare lung location.
authors.affiliation: Sección de Patología, Departamento de Diagnóstico, Facultad de Medicina, Universidad de Cartagena, Cartagena D.T. y C, Colombia.
authors.forename: Javier Alonso
authors.initials: JA
authors.lastname: Baena-Del Valle
authors.affiliation: Laboratorio de Patología, Hospital Pablo Tobón Uribe, Medellín, Colombia.
authors.forename: Victoria Eugenia
authors.initials: VE
authors.lastname: Murillo-Echeverri
authors.affiliation: Cirugía de Tórax, Hospital Pablo Tobón Uribe, Medellín, Colombia.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Gaviria-Velásquez
authors.affiliation: Servicio de Neumología, Hospital Pablo Tobón Uribe, Medellín, Colombia.
authors.forename: Diego Miguel
authors.initials: DM
authors.lastname: Celis-Mejía
authors.affiliation: Servicio de Patología, Clínica el Rosario, Universidad Pontificia Bolivariana, Medellín, Colombia. Electronic address: gumatu@gmail.com.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Matute-Turizo
mesh_terms: D000328:Adult; D005918:Glomus Tumor / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000601:surgery; D008297:Male
keywords: Computed tomography, X-Ray; Glomus tumour; Lung neoplasms; Neoplasias pulmonares; Tomografía computada por rayos X; Tumor glómico