title: A Rare Case of Optic Nerve Schwannoma: Case Report and Review of the Literature.
abstract: BACKGROUND
  Schwannomas are typically benign tumors of the peripheral nervous system that originate from Schwann cells. It is well known that the optic nerves are myelinated by oligodendrocytes since their cell bodies arise centrally within the lateral geniculate nuclei. Because of this basic cellular anatomy, optic schwannomas should theoretically not exist. It is possible, however, these rare lesions stem from small sympathetic fibers that innervate the vasculature surrounding the optic nerve and its sheath.
  
  
  METHODS
  The patient is a 46-year-old male with a one-year history of progressive right eye blurry vision. To our knowledge, there are only five known reported case of an optic nerve schwannoma. Additionally, because of its medial position relative to the optic nerve and within the orbital apex, it is the first such case to be resected via an endoscopic endonasal approach. The lesion was subtotally resected because of its adherence and continuity with the optic nerve and the patient's wish to preserve his vision. He was subsequently referred to radiation oncology for external beam radiation therapy.
  
  
  CONCLUSIONS
  Herein, we discuss the pertinent clinical findings of this rare lesion and review the literature relative to optic nerve and solitary orbital schwannomas.
authors.affiliation: Neurosurgery, University of Arizona.
authors.forename: Wyatt L
authors.initials: WL
authors.lastname: Ramey
authors.affiliation: Pathology, University of Arizona.
authors.forename: Stacy J
authors.initials: SJ
authors.lastname: Arnold
authors.affiliation: Otolaryngology, University of Arizona.
authors.forename: Alexander
authors.initials: A
authors.lastname: Chiu
authors.affiliation: University of Arizona.
authors.forename: Michael
authors.initials: M
authors.lastname: Lemole
keywords: endoscopic endonasal; myelination; optic nerve; schwannoma