title: Nutrition and Cognition in Aging Adults.
abstract: Numerous longitudinal observational studies have suggested that nutrients, such as antioxidants, B vitamins, and ω-3 fatty acids, may prevent cognitive decline or dementia. There is very little evidence from well-sized randomized controlled trials that nutritional interventions can benefit cognition in later life. Nutritional interventions may be more effective in individuals with poorer nutritional status or as part of multidomain interventions simultaneously targeting multiple lifestyle factors. Further evidence, notably from randomized controlled trials, is required to prove or refute these hypotheses.
authors.affiliation: INSERM UMR 1027, 37 allées Jules Guesde, Toulouse F-31073, France; University of Toulouse III, 37 allées Jules Guesde, Toulouse F-31073, France; Department of Epidemiology and Public Health, CHU Toulouse, 37 allées Jules Guesde, Toulouse F-31073, France. Electronic address: coley.n@chu-toulouse.fr.
authors.forename: Nicola
authors.initials: N
authors.lastname: Coley
authors.affiliation: INSERM UMR 1027, 37 allées Jules Guesde, Toulouse F-31073, France; University of Toulouse III, 37 allées Jules Guesde, Toulouse F-31073, France; Nutrition Unit, Department of Endocrinology, CHU Toulouse, 24 chemin de Pouvourville, Toulouse F-31059, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Vaurs
authors.affiliation: INSERM UMR 1027, 37 allées Jules Guesde, Toulouse F-31073, France; University of Toulouse III, 37 allées Jules Guesde, Toulouse F-31073, France; Department of Epidemiology and Public Health, CHU Toulouse, 37 allées Jules Guesde, Toulouse F-31073, France.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Andrieu
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology / Q000523:psychology; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control; D005247:Feeding Behavior / Q000502:physiology / Q000523:psychology; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D009752:Nutritional Status; D015995:Prevalence
keywords: Antioxidants; Cognitive decline; Dementia; Nutrients; Polyunsaturated fatty acids; Vitamins