title: [Dermatological manifestations of monoclonal gammopathies: contribution of cutaneous histopathology].
abstract: Skin manifestations associated with monoclonal gammapathy are common and can present with various clinical and pathological aspects. They can be the first events leading to the diagnosis of monoclonal gammapathy. They may be present either as specific lesions, including lymphoplasmacytic or pure plasma cell neoplastic infiltrates and monoclonal immunoglobulin deposits, or as non-specific dermatitis, such as leukocytoclastic vasculitis, neutrophilic dermatoses, mucinoses or xanthomatosis, giving little clues for the diagnosis of the underlying disease.
authors.affiliation: Département de pathologie, hôpital Henri-Mondor, Assistance publique-Hôpitaux de Paris (AP-HP), faculté de médecine, université Paris-Est-Créteil, 94010 Créteil cedex, France. Electronic address: drc.lacoste@gmail.com.
authors.forename: Caroline
authors.initials: C
authors.lastname: Lacoste
authors.affiliation: Service de dermatologie, hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP), 94010 Créteil cedex, France.
authors.forename: Saskia
authors.initials: S
authors.lastname: Ingen-Housz-Oro
authors.affiliation: Département de pathologie, hôpital Henri-Mondor, Assistance publique-Hôpitaux de Paris (AP-HP), faculté de médecine, université Paris-Est-Créteil, 94010 Créteil cedex, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Ortonne
mesh_terms: D000682:Amyloid / Q000032:analysis; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D017520:Mucinoses / Q000209:etiology / Q000473:pathology; D010265:Paraproteinemias / Q000150:complications / Q000473:pathology*; D010266:Paraproteins / Q000032:analysis; D010950:Plasma Cells / Q000473:pathology; D012867:Skin / Q000737:chemistry / Q000473:pathology*; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology*; D012872:Skin Diseases, Vesiculobullous; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000209:etiology / Q000473:pathology; D014973:Xanthomatosis / Q000209:etiology / Q000473:pathology
chemical_list: D000682:Amyloid; D007075:Immunoglobulin M; D010266:Paraproteins
keywords: Gammapathie monoclonale; Histopathologie cutanée; Hémopathie lymphoplasmocytaire et plasmocytaire; Monoclonal gammapathy; Plasmocytic and lymphoplasmocytic hemopathy; Skin histopathology