title: Results of second-stage screening for skin cancers in Oita Prefecture, Japan.
abstract: We performed skin cancer screenings for 2 or 3 days annually from 2006 through 2013 in Oita Prefecture, Japan. Screening of approximately 3000 people in total allowed us to identify and treat several skin cancers, including five cases of malignant melanoma, four of squamous cell carcinoma, 16 of basal cell carcinoma, 11 of Bowen's disease, 17 of actinic keratosis, one of extramammary Paget's disease and one of metastatic breast carcinoma. The sensitivity and specificity for the category defined by an identified lesion associated with risk of cancer and requiring further examination (category C) were 92.7% and 95%, respectively. We cannot estimate the outcome of our skin cancer screenings in terms of cancer mortality because of the small number of subjects examined and the brief follow-up period. However, we did estimate the effectiveness of these screenings in terms of stages or sizes of cancerous lesions. The relative numbers of subjects with malignant melanoma at various clinical stages, identified during skin cancer screenings and during a routine visit to our hospital, were significantly different. We also compared, statistically, the sizes of lesions in Bowen's disease that were found during cancer screenings and during a direct visit to our hospital. The former lesions were smaller than the latter. Our data suggest the benefits of our skin cancer screenings and the importance of campaigns and education to encourage people to visit dermatologists for the detection of skin cancers at an early stage.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Kai
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Kazushi
authors.initials: K
authors.lastname: Ishikawa
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Mayuko
authors.initials: M
authors.lastname: Goto
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Sakai
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Ito
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Shono
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Shimada
authors.affiliation: Department of Plastic Surgery, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Shimizu
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Mizuki
authors.initials: M
authors.lastname: Goto
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Hatano
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Okamoto
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Kazumoto
authors.initials: K
authors.lastname: Katagiri
authors.affiliation: Department of Public Health and Epidemiology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Aono
authors.affiliation: Department of Biostatistics, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Nobuoki
authors.initials: N
authors.lastname: Eshima
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Sakuhei
authors.initials: S
authors.lastname: Fujiwara
mesh_terms: D001913:Bowen's Disease / Q000453:epidemiology; D001943:Breast Neoplasms; D002280:Basal Cell Carcinoma / Q000453:epidemiology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D055623:Keratosis, Actinic / Q000453:epidemiology; D008297:Male; D008403:Mass Screening; D008545:Melanoma / Q000453:epidemiology; D010145:Paget Disease, Extramammary / Q000453:epidemiology; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000556:secondary
keywords: Bowen's disease; discovery rate; malignant melanoma; positive predictive value; skin cancer screening; squamous cell carcinoma