title: Iridium/copper-cocatalyzed asymmetric ring opening reaction of azabenzonorbornadienes with amines.
abstract: A combination of iridium/copper associated with (R)-Difluorphos catalyst for the asymmetric ring opening reaction of azabenzonorbornadienes with amines was developed, which afforded chiral trans-vicinal diamines in 80-97% yields with 93-95% enantioselectivities.
authors.affiliation: YMU-HKBU Joint Laboratory of Traditional Natural Medicine, Yunnan Minzu University, Kunming 650500, China. adams.bmf@hotmail.com.
authors.forename: Chaoyuan
authors.initials: C
authors.lastname: Zeng
authors.forename: Fan
authors.initials: F
authors.lastname: Yang
authors.forename: Jingchao
authors.initials: J
authors.lastname: Chen
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Baomin
authors.initials: B
authors.lastname: Fan
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry*; D009636:Norbornanes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000588:Amines; D009636:Norbornanes; D007495:Iridium; D003300:Copper