title: Synchronous breast carcinoma and chronic lymphocytic leukemia in a Chinese young female: a rare combination.
abstract: Chronic lymphocytic leukemia (CLL) is one of the most common lymphoid malignancies in western countries, however, infrequent in Eastern countries. We report on a rare case of synchronous breast carcinoma and chronic lymphocytic leukemia in a Chinese female patient. A 47-year-old female patient who presented with right breast lump for three month was admitted to our hospital. An ultrasound scan showed two mass in right breast and axillary swollen lymph node. Then, this patient was given right mastectomy and axillary lymph node dissection. Histology report showed invasive ductal carcinoma of the breast (grade I) and small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL). Bone marrow was infiltrated by CLL cell. To the best of our knowledge, this is the first report of a Chinese patient suffering from breast carcinoma and chronic lymphocytic leukemia.
authors.affiliation: Department of Oncology, The Third Affiliated Hospital of Soochow University Changzhou 213003, China.
authors.forename: Danxia
authors.initials: D
authors.lastname: Zhu
authors.affiliation: Department of Oncology, The Third Affiliated Hospital of Soochow University Changzhou 213003, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Fang
authors.affiliation: Department of Ultrasound, The Third Affiliated Hospital of Soochow University 185 Juqian Street, Changzhou 213003, Jiangsu Province, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Oncology, The Third Affiliated Hospital of Soochow University Changzhou 213003, China ; Department of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University Changzhou 213003, China.
authors.forename: Changping
authors.initials: C
authors.lastname: Wu
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001856:Bone Marrow Examination; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D002681:China; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008197:Lymph Node Excision; D008408:Mastectomy; D008875:Middle Aged; D060787:Neoplasm Grading; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016217:Ultrasonography, Mammary
chemical_list: D014408:Biomarkers, Tumor
keywords: Chronic lymphocytic leukemia; breast carcinoma; synchronous tumor