title: Advanced diffuse malignant peritoneal mesothelioma responding to palliative chemotherapy.
abstract: A 64-year-old man diagnosed with advanced malignant peritoneal mesothelioma by laparoscopic biopsy was treated with systemic chemotherapy. The patient underwent first-line chemotherapy with pemetrexed plus cisplatin for 11 months, then second-line chemotherapy with gemcitabine plus vinorelbine for 6 months, and third-line chemotherapy with CPT-11 for 4 months. After third-line chemotherapy failed, he received palliative treatment. Although the tumor continued to grow, and he died 24 months after initiation of treatment, chemotherapy prolonged the survival time and improved his quality of life.
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, University of Miyazaki Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan. kojinaka@fc.miyazaki-u.ac.jp.
authors.forename: Koji
authors.initials: K
authors.lastname: Nakashima
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, University of Miyazaki Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Inatsu
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, University of Miyazaki Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kitamura
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, University of Miyazaki Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Hikosaka
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, University of Miyazaki Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
authors.forename: Shinri
authors.initials: S
authors.lastname: Hoshiko
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, University of Miyazaki Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Ashiduka
keywords: Chemotherapy; Cisplatin; Diffuse type; Malignant peritoneal mesothelioma; Pemetrexed