title: Comparison of CT and MR angiography in evaluation of peripheral arterial disease before endovascular intervention.
abstract: BACKGROUND
  Multidetector computed tomography angiography (MDCTA) and magnetic resonance angiography (MRA) are accurate techniques for selecting patients with peripheral arterial disease for surgical and endovascular treatment. No studies in the literature have directly compared MDCTA and MRA to establish which one should be employed, in patients suitable for both techniques, before endovascular treatment.
  
  
  OBJECTIVE
  To compare diagnostic performance of MDCTA vs MRA before endovascular intervention.
  
  
  METHODS
  We prospectively compared MDCTA (64 slices scanner) and MRA (1.5 T scanner; 3D gadolinium-enhanced bolus-chase acquisition plus time resolved acquisition on calves) to stratify 35 patients according to the TASC II score and a runoff severity score. We also evaluated the accuracy of both techniques in each arterial segment. Selective angiography performed during the treatment was the standard of reference.
  
  
  RESULTS
  MDCTA and MRA accurately classify disease in the aorto-iliac (accuracy 0.92 for MDCTA and MRA) and femoro-popliteal (MDCTA 0.94, MRA 0.90) segments. MDCTA was more accurate in stratifying disease in the infrapopliteal segments (0.96 vs. 0.9) and in assessing the impairment of runoff arteries (0.92 vs. 0.85) at per-segment analysis. MDCTA showed a higher confidence and a shorter examination time.
  
  
  CONCLUSIONS
  Our results suggest that MDCTA can be considered as a first-line investigation in patients being candidates for endovascular procedures when clinical history or duplex sonographic evaluation are indicative of severe impairment of the infrapopliteal segment.
authors.affiliation: Department of Radiological Sciences, "Agostino Gemelli" Hospital, Catholic University, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Cina
authors.affiliation: Department of Radiological Sciences, "Agostino Gemelli" Hospital, Catholic University, Rome, Italy.
authors.forename: Carmine
authors.initials: C
authors.lastname: Di Stasi
authors.affiliation: Department of Radiological Sciences, "Agostino Gemelli" Hospital, Catholic University, Rome, Italy vittoriosemeraro@hotmail.it.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Semeraro
authors.affiliation: Department of Radiological Sciences, "Agostino Gemelli" Hospital, Catholic University, Rome, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Marano
authors.affiliation: Department of Radiological Sciences, "Agostino Gemelli" Hospital, Catholic University, Rome, Italy.
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Savino
authors.affiliation: Department of Radiological Sciences, "Agostino Gemelli" Hospital, Catholic University, Rome, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Iezzi
authors.affiliation: Department of Radiological Sciences, "Agostino Gemelli" Hospital, Catholic University, Rome, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Bonomo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D057510:Endovascular Procedures; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods*; D058729:Peripheral Arterial Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D011446:Prospective Studies; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media
keywords: Peripheral arterial disease; endovascular procedures; magnetic resonance angiography (MRA); multidetector computed tomography (MDCT); tibial arteries