title: Diverse display of non-covalent interacting elements using pyrimidine-embedded polyheterocycles.
abstract: A series of pyrimidine-embedded polyheterocycles was synthesized using a pDOS strategy in a facile manner. The resulting poly-heterocyclic core skeletons containing a unique aza-tricyclic framework allowed for diverse display of non-covalent interacting elements, which probably serve as essentials for perturbing specific non-covalent interactions between various biopolymers.
authors.affiliation: Department of Chemistry, Seoul National University, Seoul 151-747, Korea. sbpark@snu.ac.kr.
authors.forename: Yoona
authors.initials: Y
authors.lastname: Choi
authors.forename: Heejun
authors.initials: H
authors.lastname: Kim
authors.forename: Young-Hee
authors.initials: YH
authors.lastname: Shin
authors.forename: Seung Bum
authors.initials: SB
authors.lastname: Park
mesh_terms: D000470:Alkaloids / Q000737:chemistry; D001372:Aza Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006367:HeLa Cells; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D008958:Models, Molecular; D011743:Pyrimidines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D001372:Aza Compounds; D006575:Heterocyclic Compounds, 3-Ring; D011743:Pyrimidines; C030986:pyrimidine