title: Comparison of IgE test results with intradermal skin tests for dust mites and storage mites in atopic dogs.
abstract: Atopic dermatitis is one of the most frequent allergic diseases in dogs. There are many methods of treating its symptoms but specific immunotherapy has recently gained high popularity. Before the application of specific immunotherapy, it is necessary to identify the allergens provoking the reaction of hypersensitivity in the selected animal. This raises a question about the method of allergen identification the medical practitioner decides to use in order to obtain the most credible result. The authors of the present study decided to compare the results of intradermal allergic tests and the results of an IgE screening test carried out using the FcɛRIα receptor method. The aim of the study was to compare the results of both tests directed to dust and storage mites. The study proves that in case of the IgE screening tests (for a group of allergens), the sensitivity is quite high (85 to 90.69%) but the specificity of these tests is insufficient (25 to 50%). In case of antibodies for the selected mites the sensitivity and specificity was too low (65.1 to 89.4% for the sensitivity, with only 14.2 to 33.3% for the specificity). Only in case of D. petronyssinus the results were higher with the sensitivity calculated at 65.1% and the specificity at 80%. The IgE screening test carried out using the FcɛRIα receptor method is reliable only in case of screening test for mites and the intradermal allergic test remains the gold standard for allergy testing.
authors.forename: J
authors.initials: J
authors.lastname: Popiel
authors.forename: A
authors.initials: A
authors.lastname: Cekiera
mesh_terms: D040041:Acaridae / Q000276:immunology*; D000818:Animals; D003876:Dermatitis, Atopic / Q000276:immunology / Q000662:veterinary*; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs; D005260:Female; D007073:Immunoglobulin E / Q000276:immunology*; D007428:Intradermal Tests / Q000662:veterinary*; D008297:Male; D039981:Pyroglyphidae / Q000276:immunology*; D012680:Sensitivity and Specificity
chemical_list: D007073:Immunoglobulin E