title: Cognitive and psychological profiles in treatment compliance: a study in an elderly population with hemophilia.
abstract: Elderly patients with hemophilia have to face new challenges linked to concomitant pathologies and concurrent use of different treatments. In order to promote optimal care in the elderly hemophilia population, this study is aimed to analyze treatment compliance in relation to the presence of comorbidities and the role of potential determinants that can affect compliance (positively or negatively), including health-related quality of life, cognitive decline, and sociodemographic parameters (eg, living situation, partnership, presence of caregivers). This will be an observational study of elderly patients with hemophilia (aged >60 years). Patients will be interviewed during their routine medical visits. The data interview will pertaining to several dimension of treatment management. This study will detect more vulnerable patients with special care needs and will highlight psychological factors that should be considered for future psychosocial interventions.
authors.affiliation: Department of Health Sciences, Università degli Studi di Milano, Milan, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Riva
authors.affiliation: Department of Neuroscience, IRCCS, Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Nobili
authors.affiliation: Department of Neuroscience, IRCCS, Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
authors.forename: Codjo D
authors.initials: CD
authors.lastname: Djade
authors.affiliation: Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, IRCCS Ca' Granda, Policlinic Hospital, Milan, Italy.
authors.forename: Maria Elisa
authors.initials: ME
authors.lastname: Mancuso
authors.affiliation: Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, IRCCS Ca' Granda, Policlinic Hospital, Milan, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Santagostino
authors.affiliation: Department of Health Sciences, Università degli Studi di Milano, Milan, Italy ; Department of Neuroscience, IRCCS, Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy ; Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, IRCCS Ca' Granda, Policlinic Hospital, Milan, Italy ; European Institute of Oncology, Milan, Italy.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Pravettoni
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition; D015897:Comorbidity; D006467:Hemophilia A / Q000188:drug therapy / Q000523:psychology*; D002836:Hemophilia B / Q000188:drug therapy / Q000523:psychology*; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D012107:Research Design; D020377:Self Efficacy; D012959:Socioeconomic Factors
keywords: aging; cognitive assessment; cognitive decline; compliance; hemophilia; treatment