title: X-linked protoporphyria: Iron supplementation improves protoporphyrin overload, liver damage and anaemia.
authors.affiliation: Department of Paediatrics, University of Jena Medical School, Jena, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Landefeld
authors.affiliation: Department of Paediatrics, University of Jena Medical School, Jena, Germany.
authors.forename: Karim
authors.initials: K
authors.lastname: Kentouche
authors.affiliation: Department of Paediatrics, University of Jena Medical School, Jena, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Gruhn
authors.affiliation: MVZ Labor PD Dr. Volkmann und Kollegen, Karlsruhe, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Stauch
authors.affiliation: Department of Internal Medicine II, Klinikum Chemnitz, Chemnitz, Germany.
authors.forename: Steve
authors.initials: S
authors.lastname: Rößler
authors.affiliation: Department of Medicine I, University of Mainz Medical School, Mainz, Germany.
authors.forename: Detlef
authors.initials: D
authors.lastname: Schuppan
authors.affiliation: Department of Medical Biochemistry and Immunology, University Hospital of Wales, Cardiff, UK.
authors.forename: Sharon D
authors.initials: SD
authors.lastname: Whatley
authors.affiliation: Department of Paediatrics, University of Jena Medical School, Jena, Germany.
authors.forename: James F
authors.initials: JF
authors.lastname: Beck
authors.affiliation: Department of Internal Medicine II, Klinikum Chemnitz, Chemnitz, Germany. u.stoelzel@skc.de.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Stölzel
mesh_terms: D000624:5-Aminolevulinate Synthetase / Q000235:genetics*; D000740:Anemia / Q000188:drug therapy / Q000517:prevention & control; D002648:Child; D006801:Humans; D007501:Iron / Q000008:administration & dosage* / Q000627:therapeutic use; D008099:Liver / Q000293:injuries; D008107:Liver Diseases / Q000188:drug therapy / Q000517:prevention & control; D008297:Male; D046351:Protoporphyria, Erythropoietic / Q000145:classification / Q000175:diagnosis* / Q000628:therapy; D011524:Protoporphyrins / Q000097:blood
chemical_list: D011524:Protoporphyrins; C028025:protoporphyrin IX; D007501:Iron; D000624:5-Aminolevulinate Synthetase; C480079:ALAS2 protein, human
keywords: erythropoiesis; haem biosynthesis; iron; liver disease; porphyria