title: Near East University Genetic Mutation Database (NEU-GD): The first mutation database of Northern Cyprus.
abstract: The health care system is negatively affected by the genetic disorders that lead to an increasing rate of morbidity and neonatal deaths and affect adults as well. These create a substantial government's psychosocial and economic burden on clinicians, patients and their families with the advancement in the field of genetics. There has been a tremendous increase in the rate in which diseases associated with variant DNA sequences are being sought and identified. The goal behind the creation of Near East University Genetic Mutation Database (NEU-GD) is to map and apprehend the patterns of common genetic diversity in the human genetic makeup in order to accelerate the search for the genetic causes of human disease. NEU-GD will allow scientists to generate extraordinarily useful information such as allelic variations among population, and description of the genetic blueprint of mutations occurring in human beings. In this communication we report the construction of the first genetic mutation database for the people belonging to different ethnic groups living in North Cyprus (http://genetics-db.neu.edu.tr/). Therefore NEU-GD can serve as an important tool available online for molecular genetic testing of inherited disorder and persuade for further investigation of novel genetic disorders in North Cyprus population.
authors.affiliation: Department of Medical Genetics, Faculty of Medicine, Near East University, Near East Avenue, 99138, Nicosia, Mersin 10, Turkey. Electronic address: mahmutcerkez@gmail.com.
authors.forename: Mahmut Cerkez
authors.initials: MC
authors.lastname: Ergoren
authors.affiliation: Department of Medical Genetics, Faculty of Medicine, Near East University, Near East Avenue, 99138, Nicosia, Mersin 10, Turkey. Electronic address: rameez_hassan99@yahoo.com.
authors.forename: Rameez Hassan
authors.initials: RH
authors.lastname: Pirzada
authors.affiliation: EU-IBM Advanced Research Centre, Near East University, Near East Avenue, 99138, Nicosia, Mersin 10, Turkey. Electronic address: Mustafa.arici@neu.edu.tr.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Arici
authors.affiliation: Department of Medical Genetics, Faculty of Medicine, Near East University, Near East Avenue, 99138, Nicosia, Mersin 10, Turkey. Electronic address: nedimeserakinci@gmail.com.
authors.forename: Nedime
authors.initials: N
authors.lastname: Serakinci
mesh_terms: D003535:Cyprus / Q000453:epidemiology; D030541:Databases, Genetic; D005006:Ethnicity / Q000235:genetics; D005787:Gene Frequency; D030342:Genetic Diseases, Inborn / Q000453:epidemiology / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005828:Genetics, Population / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D020407:Internet; D009154:Mutation; D020641:Polymorphism, Single Nucleotide; D015995:Prevalence; D014495:Universities
keywords: Cyprus; Database; Genetic mutation; North Cyprus; Polymorphism