title: The role of nanotechnology in control of human diseases: perspectives in ocular surface diseases.
abstract: Nanotechnology is the creation and use of materials and devices on the same scale as molecules and intracellular structures, typically less than 100 nm in size. It is an emerging science and has made its way into pharmaceuticals to significantly improve the delivery and efficacy of drugs in a number of therapeutic areas, due to development of various nanoparticle-based products. In recent years, there has been increasing evidence that nanotechnology can help to overcome many of the ocular diseases and hence researchers are keenly interested in this science. Nanomedicines offer promise as viable alternatives to conventional drops, gels or ointments to improve drug delivery to the eye. Because of their small size, they are well tolerated, thus preventing washout, increase bioavailability and also help in specific drug delivery. This review describes the application of nanotechnology in the control of human diseases with special emphasis on various eye and ocular surfaces diseases.
authors.affiliation: a Nanobiotechnology Laboratory, Department of Biotechnology , Sant Gadge Baba Amravati University , Amravati , Maharashtra , India .
authors.forename: Mahendra
authors.initials: M
authors.lastname: Rai
authors.affiliation: a Nanobiotechnology Laboratory, Department of Biotechnology , Sant Gadge Baba Amravati University , Amravati , Maharashtra , India .
authors.forename: Avinash P
authors.initials: AP
authors.lastname: Ingle
authors.affiliation: a Nanobiotechnology Laboratory, Department of Biotechnology , Sant Gadge Baba Amravati University , Amravati , Maharashtra , India .
authors.forename: Swapnil
authors.initials: S
authors.lastname: Gaikwad
authors.affiliation: b Institute of Medicine, Pontific Catholic University of Campinas (PUCC) , Campinas , Brazil , and.
authors.forename: Felipe Hering
authors.initials: FH
authors.lastname: Padovani
authors.affiliation: c Department of Ophthalmology , State University of Campinas (UNICAMP) , Campinas , Brazil.
authors.forename: Monica
authors.initials: M
authors.lastname: Alves
mesh_terms: D000818:Animals; D005128:Eye Diseases / Q000188:drug therapy*; D006801:Humans; D053758:Nanoparticles / Q000627:therapeutic use*; D036103:Nanotechnology
keywords: Conjunctiva; drug delivery; nanomedicine; ocular diseases; ophthalmology; pterygium