title: Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease.
abstract: BACKGROUND
  Although coronary heart disease (CHD) is one of the major cardiovascular diseases, risk factors associated with the health-related quality of life (HRQoL) of CHD patients remain unclear. The present study was designed to determine the profile and significant factors of the HRQoL in CHD patients.
  
  
  METHODS
  A cross-sectional study was conducted in rural communities of Fangshan District, Beijing, China. Socio-demographic, lifestyle, and comorbidity information of CHD patients were collected by a structured questionnaire and medical records. HRQoL was measured using European Quality of Life 5-dimensions (EQ-5D) scale and EQ Visual Analog Scale (EQ-VAS). Multiple linear and logistic regressions were performed to explore the association of potential risk factors with HRQoL scores and each EQ-5D, respectively.
  
  
  RESULTS
  Totally, 1928 CHD patients (mean age 61.64 ± 9.24 years; female:male = 2.4:1) were enrolled in the study. The mean score of EQ-5D index and EQ-VAS were 0.889 ± 0.172 and 71.56 ± 17.65, respectively. Multiple linear regression revealed that marital status, physical activity, moderate alcohol drinking, and family's population were positive independent correlates of EQ-VAS, whereas diabetes mellitus and stroke were negative independent correlates (all P < 0.05). Age and stroke were negatively while physical activity, moderate alcohol drinking, family's population and household income were positively correlated with EQ-5D index (all P < 0.05) independently. In addition, each of the five HRQoL dimensions had various specific determinants, including obesity, underweight, smoking or education.
  
  
  CONCLUSIONS
  Findings of the study highlight certain socio-demographic, lifestyle factors, and comorbid stroke or diabetes mellitus as correlates of HRQoL in Chinese CHD patients. Large-scale cohort studies should be carried out to confirm our results in the future.
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.forename: Yi-Qun
authors.initials: YQ
authors.lastname: Wu
authors.forename: Xun
authors.initials: X
authors.lastname: Tang
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Liu
authors.initials: L
authors.lastname: He
authors.forename: Yang
authors.initials: Y
authors.lastname: Cao
authors.forename: Da-Fang
authors.initials: DF
authors.lastname: Chen
authors.affiliation: Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100191, China.
authors.forename: Yong-Hua
authors.initials: YH
authors.lastname: Hu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D003327:Coronary Disease / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012307:Risk Factors; D012959:Socioeconomic Factors