title: Neuropsychological and Behavioural Short-Term Effects of Cognitive Remediation Therapy in Adolescent Anorexia Nervosa: A Pilot Study.
abstract: OBJECTIVE
  Cognitive remediation therapy (CRT) aims to strengthen weak cognitive flexibility and central coherence in adult and adolescent anorexia nervosa (AN). Currently, there are no studies in adolescents with AN that control for learning effects because of re-testing while evaluating CRT.
  
  
  METHODS
  Twenty in- and outpatients with AN aged 12 to 18 years received CRT. Assessment took place directly before and after the intervention. Performance was compared to 20 age-, gender-, IQ-, and test-retest interval matched healthy controls, which did not receive CRT.
  
  
  RESULTS
  AN patients showed an improvement in flexibility on neuropsychological assessment directly after CRT, whereas HC did not improve over time. Self-report assessment of flexibility, as well as central coherence, did not show significant improvement after CRT.
  
  
  CONCLUSIONS
  Results suggest that CRT may be beneficial for enhancing flexibility in adolescents with AN. However, randomized controlled studies are essential to determine the actual efficacy of this intervention.
authors.affiliation: Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Betteke Maria
authors.initials: BM
authors.lastname: van Noort
authors.affiliation: Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Manuela Klara Aurelia
authors.initials: MK
authors.lastname: Kraus
authors.affiliation: Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Ernst
authors.initials: E
authors.lastname: Pfeiffer
authors.affiliation: Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Ulrike
authors.initials: U
authors.lastname: Lehmkuhl
authors.affiliation: Department of Child and Adolescent Psychiatry, Psychosomatic Medicine and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Viola
authors.initials: V
authors.lastname: Kappel
mesh_terms: D000293:Adolescent; D000856:Anorexia Nervosa / Q000523:psychology* / Q000628:therapy*; D002648:Child; D003071:Cognition / Q000502:physiology; D015928:Cognitive Behavioral Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010865:Pilot Projects; D057566:Self Report; D016896:Treatment Outcome
keywords: adolescents; anorexia nervosa; central coherence; cognitive flexibility; cognitive remediation therapy