title: Lung abscess caused by Mycoplasma pneumoniae.
abstract: A 10-year-old boy with West syndrome was referred to hospital because of high fever and cough. Chest X-ray and computed tomography showed consolidation with an abscess in the right upper lobe. Laboratory data indicated cytokine storm. Various antibacterial agents and additional corticosteroid were unable to control the hypercytokinemia, which was suppressed after cyclosporine A was started. The lung abscess remained, however, and right upper lobectomy was performed. Culture from the abscess showed no growth, while polymerase chain reaction assay indicated Mycoplasma pneumoniae DNA. Serum passive agglutinin titer for M. pneumoniae was significantly elevated in the convalescent phase. These findings are strong evidence that the lung abscess was caused by M. pneumoniae infection.
authors.affiliation: Department of Pediatrics, Seirei Hamamatsu General Hospital, Shizuoka, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Omae
authors.affiliation: Department of Pediatrics, Seirei Hamamatsu General Hospital, Shizuoka, Japan.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Matsubayashi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D016572:Cyclosporine / Q000627:therapeutic use; D016207:Cytokines / Q000097:blood; D006801:Humans; D008168:Lung / Q000473:pathology*; D008169:Lung Abscess / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D008297:Male; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D011013:Pneumonectomy; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D016207:Cytokines; D016572:Cyclosporine
keywords: Mycoplasma pneumoniae; child; hypercytokinemia; lung abscess