title: MR Imaging Findings of a Leiomyosarcoma of the Thoracic Spine: A Case Report.
abstract: We report a case of leiomyosarcoma of the thoracic spine. Primary leiomyosarcoma is a malignant connective tissue tumor originating from smooth muscle cells. Leiomyosarcoma frequently occurs in the uterus, retroperitoneal space, gastrointestinal tract, and deep soft tissues; primary leiomyosarcoma of the bone is rare. The MR imaging including intravoxel incoherent motion (IVIM) imaging findings of the current case indicated a low diffusion coefficient and high blood flow, which were in concurrence with high cell density on histology and increased vascularity by angiography. Although some benign tumors such as osteoblastoma and giant cell tumor would show similar findings on IVIM imaging, these additional imaging features may narrow the differential diagnosis of spinal tumors.
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tahara
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan. yamakou@radiol.med.kyushu-u.ac.jp.
authors.forename: K
authors.initials: K
authors.lastname: Yamashita
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Hiwatashi
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan.
authors.forename: O
authors.initials: O
authors.lastname: Togao
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kikuchi
authors.affiliation: Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Endo
authors.affiliation: Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Otsuka
authors.affiliation: Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Oda
authors.affiliation: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, 3-1-1, Maidashi, Higashi-ku, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Honda
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging* / Q000473:pathology
keywords: IVIM; Leiomyosarcoma; MR; Spine