title: Digynic triploidy: utility and challenges of noninvasive prenatal testing.
abstract: Low fraction fetal DNA in noninvasive prenatal testing in the context of fetal growth restriction and multiple congenital anomalies should alert medical professionals to the possibility of digynic triploidy. Single-nucleotide polymorphism microarray can detect the parental origin of triploidy and explain its mechanism.
authors.affiliation: Department of Pediatrics, Division of Genetics and Genomic Medicine, Washington University School of Medicine St. Louis, Missouri.
authors.forename: Julie
authors.initials: J
authors.lastname: Fleischer
authors.affiliation: Department of Pathology and Immunology, Washington University School of Medicine St. Louis, Missouri.
authors.forename: Archana
authors.initials: A
authors.lastname: Shenoy
authors.affiliation: Department of Obstetrics and Gynecology, Washington University School of Medicine St. Louis, Missouri.
authors.forename: Katherine
authors.initials: K
authors.lastname: Goetzinger
authors.affiliation: Department of Pathology and Immunology, Washington University School of Medicine St. Louis, Missouri.
authors.forename: Catherine E
authors.initials: CE
authors.lastname: Cottrell
authors.affiliation: Department of Pediatrics, Division of Genetics and Genomic Medicine, Washington University School of Medicine St. Louis, Missouri.
authors.forename: Dustin
authors.initials: D
authors.lastname: Baldridge
authors.affiliation: Department of Pathology and Immunology, Washington University School of Medicine St. Louis, Missouri.
authors.forename: Frances V
authors.initials: FV
authors.lastname: White
authors.affiliation: Department of Pediatrics, Division of Genetics and Genomic Medicine, Washington University School of Medicine St. Louis, Missouri.
authors.forename: Marwan
authors.initials: M
authors.lastname: Shinawi
keywords: NIPT; SNP array; cffDNA; digyny; triploidy