title: Pleomorphic Adenoma with Sarcomatous Change in a Lacrimal Gland.
abstract: A 69-year-old man was referred with left exophthalmos. Computed tomographic (CT) findings detected a well-circumscribed mass in the left side of the intraorbital cavity. At that time, he refused the further evaluation and treatment. About three years later, the size of the mass had enlarged, and the patient's symptoms were getting worse. The mass was completely removed with frontotemporal craniotomy and superolateral orbitotomy. In operative findings, the mass had originated in the lacrimal gland and was well-encapsulated without invasion to the surrounding tissue. In the pathologic findings, the tumor consisted of pleomorphic adenoma with osteosarcomatous change of stromal components. Postoperatively, the adjuvant radiotherapy was done four weeks later. The patient's symptoms were improved. The pleomorphic adenoma with osteosarcomatous change is extremely rare and appropriate treatment is not clearly established. We would like to report this rare case with a review of the literature.
authors.affiliation: Department of Neurosurgery, College of Medicine, Dong-A University, Busan, Korea.
authors.forename: Kyoung-Su
authors.initials: KS
authors.lastname: Sung
authors.affiliation: Department of Pathology, College of Medicine, Dong-A University, Busan, Korea.
authors.forename: Dae-Cheol
authors.initials: DC
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, College of Medicine, Dong-A University, Busan, Korea.
authors.forename: Hee-Bae
authors.initials: HB
authors.lastname: Ahn
authors.affiliation: Department of Neurosurgery, College of Medicine, Dong-A University, Busan, Korea.
authors.forename: Young-Jin
authors.initials: YJ
authors.lastname: Song
keywords: Lacrimal gland; Malignant mixed tumor; Pleomorphic adenoma; Sarcoma