title: Nutritional supplements in support of resistance exercise to counter age-related sarcopenia.
abstract: Age-related sarcopenia, composed of myopenia (a decline in muscle mass) and dynapenia (a decline in muscle strength), can compromise physical function, increase risk of disability, and lower quality of life in older adults. There are no available pharmaceutical treatments for this condition, but evidence shows resistance training (RT) is a viable and relatively low-cost treatment with an exceptionally positive side effect profile. Further evidence suggests that RT-induced increases in muscle mass, strength, and function can be enhanced by certain foods, nutrients, or nutritional supplements. This brief review focuses on adjunctive nutritional strategies, which have a reasonable evidence base, to enhance RT-induced gains in outcomes relevant to sarcopenia and to reducing risk of functional declines.
authors.affiliation: Department of Kinesiology, McMaster University, Hamilton, Canada phillis@mcmaster.ca.
authors.forename: Stuart M
authors.initials: SM
authors.lastname: Phillips
mesh_terms: D000368:Aged; D000375:Aging; D003401:Creatine / Q000008:administration & dosage; D004032:Diet; D004044:Dietary Proteins / Q000008:administration & dosage; D019587:Dietary Supplements; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007930:Leucine / Q000008:administration & dosage; D008297:Male; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000473:pathology / Q000503:physiopathology; D011788:Quality of Life; D055070:Resistance Training; D055948:Sarcopenia / Q000628:therapy*; D014631:Valerates / Q000008:administration & dosage
chemical_list: D004044:Dietary Proteins; D015525:Fatty Acids, Omega-3; D014631:Valerates; C004961:beta-hydroxyisovaleric acid; D007930:Leucine; D003401:Creatine
keywords: Leu; aging; creatine; dynapenia; function; protein; vitamin D; β-HMB