title: Diagnosis of Dissection of the Coronary Artery Dissection by Multidetector Computed Tomography: A Comparative Study With Coronary Angiology.
abstract: OBJECTIVE
  This study was to assess the diagnostic performance of multidetector computed tomography (MDCT) angiographic protocol for dissection of the coronary artery (DCA) detection compared with coronary angiology (CAG).
  
  
  METHODS
  Intravascular ultrasound was used as the gold standard for DCA diagnosis. Thirty-six DCA patients and 34 non-DCA (control) participants were retrospectively reviewed. The CAG and MDCT angiography images were separately reviewed by 4 independent observers, and a 5-point grading scale was used for DCA diagnosis. Diagnostic performance was compared using receiver operating characteristic analysis. Sensitivity, specificity, and negative predictive values were calculated.
  
  
  RESULTS
  The MDCT performed significantly better than that of CAG (AZ = 0.9943 ± 0.0034 vs AZ = 0.8411 ± 0.0274, respectively) for DCA detection. The sensitivity (98.6%), specificity (89.7%), and negative predictive value (98.4%) of MDCT for DCA were higher than those of CAG (77.8%, 79.4%, and 77.1%, respectively).
  
  
  CONCLUSIONS
  Multidetector computed tomography angiography was a more sensitive and specific technique for the diagnosis of DCA compared with CAG.
authors.affiliation: From the Departments of *Radiology and †Cardiology, Huadong Hospital, Fudan University, Shanghai, China.
authors.forename: Yibo
authors.initials: Y
authors.lastname: Sun
authors.forename: Dingbiao
authors.initials: D
authors.lastname: Mao
authors.forename: Fang
authors.initials: F
authors.lastname: Lu
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.forename: Kailei
authors.initials: K
authors.lastname: Shi
authors.forename: Lin
authors.initials: L
authors.lastname: Qi
authors.forename: Xingui
authors.initials: X
authors.lastname: Guo
authors.forename: Yanqing
authors.initials: Y
authors.lastname: Hua
mesh_terms: D000328:Adult; D003287:Contrast Media; D017023:Coronary Angiography / Q000379:methods*; D003330:Coronary Vessel Anomalies / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007479:Iopamidol; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods*; D015588:Observer Variation; D011237:Predictive Value of Tests; D011856:Radiographic Image Enhancement; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014652:Vascular Diseases / Q000151:congenital* / Q000000981:diagnostic imaging
chemical_list: D003287:Contrast Media; D007479:Iopamidol