title: Bismuth coordination networks containing deferiprone: synthesis, characterisation, stability and antibacterial activity.
abstract: A series of bismuth-dicarboxylate-deferiprone coordination networks have been prepared and structurally characterised. The new compounds have been demonstrated to release the iron overload drug deferiprone on treatment with PBS and have also been shown to have antibacterial activity against H. pylori.
authors.affiliation: Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK. a.d.burrows@bath.ac.uk.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Burrows
authors.forename: Monika
authors.initials: M
authors.lastname: Jurcic
authors.forename: Mary F
authors.initials: MF
authors.lastname: Mahon
authors.forename: Sandrine
authors.initials: S
authors.lastname: Pierrat
authors.forename: Gavin W
authors.initials: GW
authors.lastname: Roffe
authors.forename: Henry J
authors.initials: HJ
authors.lastname: Windle
authors.forename: John
authors.initials: J
authors.lastname: Spencer
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001729:Bismuth / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D056831:Coordination Complexes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D000077543:Deferiprone; D004355:Drug Stability; D016480:Helicobacter pylori / Q000187:drug effects; D008958:Models, Molecular; D008968:Molecular Conformation; D011728:Pyridones / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D056831:Coordination Complexes; D011728:Pyridones; D000077543:Deferiprone; D001729:Bismuth