title: Optic Disc Melanocytoma Report of 5 Patients From Singapore With a Review of the Literature.
abstract: OBJECTIVE
  The aim of this study was to report the clinical features of optic disc melanocytoma (ODMC).
  
  
  METHODS
  This study was a retrospective case series.
  
  
  METHODS
  Five patients (6 eyes) with ODMC followed up over a mean duration of 3 years (range, 4-61 months) were included in this series.
  
  
  RESULTS
  The mean age of diagnosis was 55.2 years with Chinese female predominance. Four of 6 ODMCs were unilateral with predominance to the left side. Four patients had visual acuity of 6/9 or better at presentation, and all ODMCs were discovered incidentally. All ODMCs were black, with an average size of 0.8 disc diameter and partially covering the optic disc. Five of 6 ODMCs were inferiorly located and involved adjacent choroid and retina. Three of 6 ODMCs had ill-defined borders. Fundus fluorescein angiogram findings in 1 patient showed blocked fluorescence due to pigments. No loss of visual acuity of 2 or more Snellen lines, ODMC enlargement, or malignant transformation were noted in any patients during follow-up. There were no local complications. Ocular and systemic associations were not seen.
  
  
  CONCLUSIONS
  Our case series did not show any features of progression during our follow-up. Annual fundoscopic examinations are still important to detect enlargement and malignant transformation.
authors.affiliation: From the *Department of Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital; †Ministry of Health Holdings; and ‡Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Elin
authors.initials: E
authors.lastname: Lee
authors.forename: Srinivasan
authors.initials: S
authors.lastname: Sanjay
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009508:Nevus, Pigmented / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D019574:Optic Nerve Neoplasms / Q000473:pathology*; D012189:Retrospective Studies; D012846:Singapore; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology