title: Late postoperative choroidal detachment following an uneventful cataract surgery in a patient on topical latanoprost.
abstract: Topical latanoprost is a most effective and commonly used antiglaucoma medication. Use of prostaglandin analogues (PGA) in the early postoperative period is controversial due to its proinflammatory properties. We report a case of a 64-year-old man with primary open angle glaucoma, post-trabeculectomy 17 years prior, with good intraocular pressure (IOP) control on topical levobunolol 0.5% and latanoprost 0.005%. He underwent a clear corneal phacoemulsification surgery in his left eye and the PGA was stopped. He had an uneventful postoperative course and was prescribed eyeglasses at 4-week follow-up. Two weeks later, he presented to the emergency department with decreased vision in the left eye, flat anterior chamber, IOP of 00 mm Hg and 360° choroidal detachment. The continued use of topical latanoprost in the operated eye was implicated as the cause. This case illustrates the serious vision-threatening side effect of PGA when used in the early postoperative period.
authors.affiliation: Department of Glaucoma, L V Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Krishnamurthy
authors.affiliation: Department of Glaucoma, L V Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Sirisha
authors.initials: S
authors.lastname: Senthil
authors.affiliation: Department of Glaucoma, L V Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Chandrasekhar S
authors.initials: CS
authors.lastname: Garudadri
mesh_terms: D000287:Administration, Topical; D000867:Anterior Chamber / Q000473:pathology; D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use; D002386:Cataract / Q000150:complications; D002387:Cataract Extraction / Q000379:methods*; D002829:Choroid / Q000473:pathology*; D015862:Choroid Diseases / Q000209:etiology*; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000517:prevention & control / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D000077338:Latanoprost; D019654:Lens Implantation, Intraocular; D008297:Male; D008508:Medication Errors; D008875:Middle Aged; D015814:Ocular Hypotension / Q000209:etiology; D018918:Phacoemulsification; D011182:Postoperative Care; D011183:Postoperative Complications; D011461:Prostaglandins F, Synthetic / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D014065:Tonometry, Ocular; D014130:Trabeculectomy; D014792:Visual Acuity
chemical_list: D000959:Antihypertensive Agents; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost