title: Chromosome Segregation: A Spatial Code to Correct Kinetochore-Microtubule Attachments.
abstract: Erroneous kinetochore-microtubule interactions must be detected and corrected before a cell enters anaphase to prevent chromosome mis-segregation. Two new studies describe an Aurora A-mediated error correction mechanism based on the spatial position of a chromosome within the mitotic spindle.
authors.affiliation: Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Department of Biology, MIT, Nine Cambridge Center, Cambridge, MA 02142, USA.
authors.forename: Julie K
authors.initials: JK
authors.lastname: Monda
authors.affiliation: Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Department of Biology, MIT, Nine Cambridge Center, Cambridge, MA 02142, USA. Electronic address: icheese@wi.mit.edu.
authors.forename: Iain M
authors.initials: IM
authors.lastname: Cheeseman
mesh_terms: D000818:Animals; D064096:Aurora Kinase A / Q000235:genetics*; D016764:Cell Polarity; D045584:Chromosome Positioning; D020090:Chromosome Segregation; D059006:Chromosomes, Insect / Q000378:metabolism*; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D018386:Kinetochores / Q000378:metabolism*; D008540:Meiosis; D008870:Microtubules / Q000378:metabolism*; D064047:Spindle Poles / Q000378:metabolism*
chemical_list: D029721:Drosophila Proteins; D064096:Aurora Kinase A