title: Persistent Pulmonary Hypertension in a Neonate With Transposition of Great Arteries and Intact Ventricular Septum: A Case Report and Review of the Literature.
abstract: Transposition of the great arteries (TGA) with intact ventricular septum (IVS) has very favorable short- and long-term surgical outcome. Although rare, when associated with persistent pulmonary hypertension (PPH), it exhibits significant mortality risk and management challenges. We report the case of a neonate with TGA with IVS and PPH who underwent successful early surgical repair with emphasis on clinical management and review of the literature.
authors.affiliation: Department of Surgery, Section of Cardiac Surgery, Pediatric Cardiothoracic Surgery, Northeast Pediatric Specialties (NEPS), Yale University School of Medicine, New Haven, CT, USA Connecticut Children's Medical Center, Hartford, CT, USA mohsen.karimi@yale.edu.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Karimi
authors.affiliation: Department of Surgery, Section of Cardiac Surgery, Pediatric Cardiothoracic Surgery, Northeast Pediatric Specialties (NEPS), Yale University School of Medicine, New Haven, CT, USA Connecticut Children's Medical Center, Hartford, CT, USA.
authors.forename: Paul M
authors.initials: PM
authors.lastname: Kirshbom
authors.affiliation: Department of Surgery, Section of Cardiac Surgery, Pediatric Cardiothoracic Surgery, Northeast Pediatric Specialties (NEPS), Yale University School of Medicine, New Haven, CT, USA Connecticut Children's Medical Center, Hartford, CT, USA.
authors.forename: Gary S
authors.initials: GS
authors.lastname: Kopf
authors.affiliation: Department of Surgery, Section of Cardiac Surgery, Pediatric Cardiothoracic Surgery, Northeast Pediatric Specialties (NEPS), Yale University School of Medicine, New Haven, CT, USA Connecticut Children's Medical Center, Hartford, CT, USA.
authors.forename: Margaret M
authors.initials: MM
authors.lastname: Steele
authors.affiliation: Department of Surgery, Section of Cardiac Surgery, Pediatric Cardiothoracic Surgery, Northeast Pediatric Specialties (NEPS), Yale University School of Medicine, New Haven, CT, USA Connecticut Children's Medical Center, Hartford, CT, USA.
authors.forename: Jill M
authors.initials: JM
authors.lastname: Sullivan
mesh_terms: D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000151:congenital; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology*; D007231:Infant, Newborn; D014188:Transposition of Great Vessels / Q000150:complications*; D054088:Ventricular Septum
keywords: congenital heart disease; neonate; persistent pulmonary hypertension; transposition of the great arteries with intact ventricular septum