title: Long-Lasting Permethrin-Impregnated Clothing Protects Against Mosquito Bites in Outdoor Workers.
abstract: Outdoor exposure to mosquitoes is a risk factor for many diseases, including malaria and dengue. We have previously shown that long-lasting permethrin-impregnated clothing protects against tick and chigger bites in a double-blind randomized controlled trial in North Carolina outdoor workers. Here, we evaluated whether this clothing is protective against mosquito bites by measuring changes in antibody titers to mosquito salivary gland extracts. On average, there was a 10-fold increase in titer during the spring and summer when mosquito exposure was likely to be the highest. During the first year of the study, the increase in titer in subjects wearing treated uniforms was 2- to 2.5-fold lower than that of control subjects. This finding suggests that long-lasting permethrin-impregnated clothing provided protection against mosquito bites.
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana berlinlondo@yahoo.com.
authors.forename: Berlin
authors.initials: B
authors.lastname: Londono-Renteria
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Jaymin C
authors.initials: JC
authors.lastname: Patel
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Meagan
authors.initials: M
authors.lastname: Vaughn
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Sheana
authors.initials: S
authors.lastname: Funkhauser
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Loganathan
authors.initials: L
authors.lastname: Ponnusamy
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Crystal
authors.initials: C
authors.lastname: Grippin
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Sam B
authors.initials: SB
authors.lastname: Jameson
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Charles
authors.initials: C
authors.lastname: Apperson
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Christopher N
authors.initials: CN
authors.lastname: Mores
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Dawn M
authors.initials: DM
authors.lastname: Wesson
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Tonya M
authors.initials: TM
authors.lastname: Colpitts
authors.affiliation: Department of Pathology, Immunology and Microbiology, University of South Carolina, Columbia, South Carolina; Department of Tropical Medicine, Tulane University, New Orleans, Louisiana; Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill, North Carolina; Department of Entomology, North Carolina State University, Raleigh, North Carolina; Department of Pathobiological Sciences, Louisiana State University, Baton Rouge, Louisiana.
authors.forename: Steven R
authors.initials: SR
authors.lastname: Meshnick
mesh_terms: D000330:Aedes / Q000276:immunology*; D000818:Animals; D000906:Antibodies / Q000276:immunology; D015153:Blotting, Western; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007299:Insect Bites and Stings / Q000517:prevention & control*; D007306:Insecticides; D026023:Permethrin; D011481:Protective Clothing; D012463:Saliva / Q000276:immunology
chemical_list: D000906:Antibodies; D007306:Insecticides; D026023:Permethrin