title: [Clinical characteristics among CABG or PCI which to treat chronic kidney disease with unprotected left main coronary artery disease].
abstract: OBJECTIVE
  To explore the clinical characteristics and prognosis of patients with chronic kidney disease with unprotected left main (ULM) coronary artery disease undergoing coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI).
  
  
  METHODS
  A total of 601 unprotected left main coronary artery disease patients were recruited. According to the values of endogenous creatinine clearance rate (Ccr), they were divided into three groups of <45 ml/min (n=40), 45-59 ml/min (n=96) and ≥60 ml/min (n=465). Retrospective comparisons were made for the clinical parameters and prognosis of ULM patients in different Ccr groups with different therapies.
  
  
  RESULTS
  In Ccr≥60 ml/min group, the valves of left ventricular ejection fraction (LVEF) were lower in patients undergoing CABG. Patients with complete total occlusion (CTO) and complete revascularizations were much more than those undergoing PCI. In Ccr≥60 ml/min and Ccr 45-59 ml/min groups, multivessel disease was frequent in CABG-treated patients. No significant difference existed among three groups in major adverse cardiac and cerebrovascular event (MACCE), overall mortality or cardiac mortality.
  
  
  CONCLUSIONS
  PCI is both safe and efficacious for chronic renal insufficiency patients with ULM.
authors.affiliation: Department of Cardiology, Affiliated Anzhen Hospital, Beijing 100029, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Pan
authors.affiliation: Institute of Clinical Pharmacology, Affiliated Anzhen Hospital, Beijing 100029, China; Email: qiuqi@anzhengcp.com.
authors.forename: Qi
authors.initials: Q
authors.lastname: Qiu
authors.forename: Yunting
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yawei
authors.initials: Y
authors.lastname: Luo
authors.forename: Xianpeng
authors.initials: X
authors.lastname: Yu
authors.forename: Jiqiang
authors.initials: J
authors.lastname: He
authors.forename: Quan
authors.initials: Q
authors.lastname: Li
mesh_terms: D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease; D006801:Humans; D062645:Percutaneous Coronary Intervention; D051436:Renal Insufficiency, Chronic; D012189:Retrospective Studies; D016896:Treatment Outcome