title: Cross-cultural adaptation and validation of the osteoporosis assessment questionnaire short version (OPAQ-SV) for Chinese osteoporotic fracture females.
abstract: The Osteoporosis Assessment Questionnaire Short Version (OPAQ-SV) was cross-culturally adapted to measure health-related quality of life in Chinese osteoporotic fracture females and then validated in China for its psychometric properties. Cross-cultural adaptation, including translation of the original OPAQ-SV into Mandarin Chinese language, was performed according to published guidelines. Validation of the newly cross-culturally adapted OPAQ-SV was conducted by sampling 234 Chinese osteoporotic fracture females and also a control group of 235 Chinese osteoporotic females without fractures, producing robust content, construct, and discriminant validation results. Major categories of reliability were also met: the Cronbach alpha coefficient was 0.975, indicating good internal consistency; the test-retest reliability was 0.80; and principal component analysis resulted in a 6-factor structure explaining 75.847 % of the total variance. Further, the Comparative Fit Index result was 0.922 following the modified model confirmatory factor analysis, and the chi-squared test was 1.98. The root mean squared error of approximation was 0.078. Moreover, significant differences were revealed between females with fractures and those without fractures across all domains (p < 0.001). Overall, the newly cross-culturally adapted OPAQ-SV appears to possess adequate validity and reliability and may be utilized in clinical trials to assess the health-related quality of life in Chinese osteoporotic fracture females.
authors.affiliation: Health Science Center, Xi'an Jiaotong University, No.76, West Yanta Road, Xi'an, Shaanxi, 710061, People's Republic of China. cathyzh@mail.xjtu.edu.cn.
authors.forename: Yin-Ping
authors.initials: YP
authors.lastname: Zhang
authors.affiliation: Health Science Center, Xi'an Jiaotong University, No.76, West Yanta Road, Xi'an, Shaanxi, 710061, People's Republic of China.
authors.forename: Huan-Huan
authors.initials: HH
authors.lastname: Wei
authors.affiliation: Health Science Center, Xi'an Jiaotong University, No.76, West Yanta Road, Xi'an, Shaanxi, 710061, People's Republic of China.
authors.forename: Wen
authors.initials: W
authors.lastname: Wang
authors.affiliation: Health Science Center, Xi'an Jiaotong University, No.76, West Yanta Road, Xi'an, Shaanxi, 710061, People's Republic of China.
authors.forename: Ru-Yi
authors.initials: RY
authors.lastname: Xia
authors.affiliation: Department of Orthopaedics, the 1st Attached Hospital, Xi'an Jiaotong University, Xi'an, 710061, People's Republic of China.
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Zhou
authors.affiliation: School of Nursing, Memorial University, St. John's, NL, A1B 3V6, Canada.
authors.forename: Caroline
authors.initials: C
authors.lastname: Porr
authors.affiliation: Department of Integrative Medical Biology, University of Umea, 90187, Umea, Sweden.
authors.forename: Mikko
authors.initials: M
authors.lastname: Lammi
mesh_terms: D000368:Aged; D000465:Algorithms; D044466:Asian People; D002681:China; D003431:Cross-Cultural Comparison; D003466:Cultural Characteristics; D005260:Female; D006620:Hip Fractures; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D015233:Models, Statistical; D058866:Osteoporotic Fractures / Q000175:diagnosis* / Q000503:physiopathology* / Q000523:psychology; D010865:Pilot Projects; D011594:Psychometrics / Q000379:methods*; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires
keywords: Fracture; Osteoporosis; Quality of life; Questionnaire; Validation