title: Evaluation and Management of Febrile, Well-appearing Young Infants.
abstract: The evaluation and management of well-appearing febrile infants less than 3 months of age has presented a decades-long clinical conundrum for providers. This article reviews the epidemiology of bacterial and viral infections in these infants. It discusses evidence-based diagnostic and treatment strategies, including appropriate use of testing, admission to the hospital, use of antibiotics, and hospital discharge. It also highlights the substantial variation in care for febrile infants and provides strategies to standardize practice.
authors.affiliation: Department of Pediatrics, University of Rochester Medical Center, 601 Elmwood Avenue, Box #667, Rochester, NY 14642, USA. Electronic address: eric_biondi@urmc.rochester.edu.
authors.forename: Eric A
authors.initials: EA
authors.lastname: Biondi
authors.affiliation: Department of Pediatrics, University of Utah, HSEB Suite 5515, 26 South 2000 East, Salt Lake City, UT 84112, USA.
authors.forename: Carrie L
authors.initials: CL
authors.lastname: Byington
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy; D001424:Bacterial Infections / Q000175:diagnosis* / Q000503:physiopathology; D019468:Disease Management; D005334:Fever / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D006760:Hospitalization / Q000191:economics / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D014777:Virus Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D000900:Anti-Bacterial Agents
keywords: Fever; Infant; Management; Serious bacterial infection; Viral illness