title: [Therapeutic evaluation of He-wei Jie-gu (Chinese characters)Decoction on femoral intertrochanteric fracture after internal fixation in elderly: a randomized controlled trial].
abstract: OBJECTIVE
  To observe the efficacy of He-wei Jie-gu (Chinese characters) decoction on femoral intertrochanteric fractures after internal fixation in elderly.
  
  
  METHODS
  From January 2010 to January 2012, 90 elderly patients with osteoporotic intertrochanteric fracture were randomly divided into two groups. The patients in experimental group were treated with open reduction and internal fixation, He-wei Jie-gu decoction and Caltrate D in oral, including 18 males and 27 females with an average age of (77.8±11.3) years old ranging from 65 to 89 years old;the time from injured to operation was 2 to 9 days with an average of (6.6±2.1) days; according to Evans-Jensen classification, 17 cases were in type I, 8 in type II, 15 in type III, 3 in type IV, 2 in type V. Meanwhile, the patients in control group were treated with open reduction and internal fixation, Caltrate D in oral, including 16 males and 29 females with an average age of (81.2±9.6) years old ranging from 67 to 91 years old; the time from injury to operation was 2 to 10 days with an average of (6.8±2.6) days; according to Evans-Jensen classification, 15 cases were in type I, 10 in type II, 14 in type III, 4 in type W, 2 in type V. The VAS score, hip BMD value before and after treatment, fracture healing and the Harris function score after operation were recorded and compared.
  
  
  RESULTS
  All patients were followed up from 3 to 9 months with an average of (5.6±2.8) months. Compared with the control group, the VAS score of the experimental group had an obviously reduction (F=98.138, P<0.01) after treatment; the hip BMD value at 3 months after treatment in the experimental group was higher than that of the control group (P<0.05); the fracture healing rate of the experimental group was higher than that of the control group (P<0.05); Harris score in 3 months of follow-up in the experimental group was higher than that of the control group (t=2.542, P<0.05); all the differences between two groups were statistically significant (P<0.05).
  
  
  CONCLUSIONS
  He-wei Jie-gu decoction can reduce postoperative pain and increase bone mineral density after internal fixation of femoral intertrochanteric fracture in elderly, promote the fracture healing and functional recovery in the hip joint.
authors.forename: Lu-wen
authors.initials: LW
authors.lastname: Shen
authors.forename: Hui
authors.initials: H
authors.lastname: Zhou
authors.forename: Zhi-ming
authors.initials: ZM
authors.lastname: Xia
authors.forename: Yi-you
authors.initials: YY
authors.lastname: Fang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D005269:Femur / Q000293:injuries / Q000601:surgery*; D005593:Fracture Fixation, Internal; D006620:Hip Fractures / Q000601:surgery; D006801:Humans; D008297:Male; D058866:Osteoporotic Fractures / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D010149:Postoperative Pain / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D004365:Drugs, Chinese Herbal