title: Spontaneous rupture of a hepatic angiomyolipoma: Report of a case.
abstract: A 70-year-old female experienced sudden onset of back pain on the right side and was admitted to our hospital in December 2010. Abdominal computed tomography revealed an S7 hepatic mass measuring 7 cm in diameter accompanied by a subcapsular hematoma. Emergency angiography confirmed the diagnosis of a ruptured hepatic mass, and hemostasis was carried out by embolization of A8 and A7 of the liver. A right hepatic lobectomy was carried out 39 days following transarterial embolization. Although almost all aspects of the tumor were necrotic, residual tumor cells stained positive for HMB-45, and negative for α-SMA, S-100, CD 34, c-kit, CAM 5.2, and hepatocytes. The MIB-1 index was 2 %. Pathological diagnosis was hepatic angiomyolipoma (HAML). The patient has shown no signs of recurrence at 42 months following surgery. Here, we report on this case of spontaneous HAML rupture and discuss therapeutic strategies for HAML and ruptured hepatic tumors.
authors.affiliation: Department of Surgery, National Hospital Iwakuni Clinical Center, 1-1-1 Atago-cho, Iwakuni, Yamaguchi, 740-8510, Japan, aoki@iwakuni-nh.go.jp.
authors.forename: Hideki
authors.initials: H
authors.lastname: Aoki
authors.forename: Takashi
authors.initials: T
authors.lastname: Arata
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Morihiro
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Kanaya
authors.forename: Sho
authors.initials: S
authors.lastname: Takeda
authors.forename: Kenta
authors.initials: K
authors.lastname: Sui
authors.forename: Kunitoshi
authors.initials: K
authors.lastname: Shigeyasu
authors.forename: Koh
authors.initials: K
authors.lastname: Katsuda
authors.forename: Kohji
authors.initials: K
authors.lastname: Tanakaya
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Takeuchi
mesh_terms: D000368:Aged; D018207:Angiomyolipoma / Q000150:complications*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications*; D012422:Rupture, Spontaneous