title: Synthesis, characterization and study of antioxidant activity of quercetin-magnesium complex.
abstract: Quercetin (3,3',4',5,7-pentahydroxyflavone) one of the most abundant dietary flavonoids, has been investigated in the presence of magnesium (II) in methanol. The complex formation between quercetin and magnesium (II) was examined under UV-visible, Infra-red and (1)H NMR spectroscopic techniques. The spectroscopic data denoted that quercetin can reacts with magnesium cation (Mg(+2)) through the chelation site in the quercetin molecule. The free radical antioxidant activity of the complex with respect to the parent molecule was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. It was observed that the free radical scavenging activity of quercetin was increased after complexation of magnesium (Mg(+2)) cation.
authors.affiliation: NSHM Knowledge Campus Kolkata, Group of Institutions, 124-BL Saha Road, Kolkata, West Bengal 700053, India.
authors.forename: Nilanjan
authors.initials: N
authors.lastname: Ghosh
authors.affiliation: NSHM Knowledge Campus Kolkata, Group of Institutions, 124-BL Saha Road, Kolkata, West Bengal 700053, India.
authors.forename: Tania
authors.initials: T
authors.lastname: Chakraborty
authors.affiliation: NSHM Knowledge Campus Kolkata, Group of Institutions, 124-BL Saha Road, Kolkata, West Bengal 700053, India.
authors.forename: Sougata
authors.initials: S
authors.lastname: Mallick
authors.affiliation: NSHM Knowledge Campus Kolkata, Group of Institutions, 124-BL Saha Road, Kolkata, West Bengal 700053, India.
authors.forename: Supriya
authors.initials: S
authors.lastname: Mana
authors.affiliation: Nightingale Diagnostic & Medicare Centre Pvt Ltd., 11, Shakespeare Sarani, Kolkata, West Bengal 700071, India.
authors.forename: Deepanwita
authors.initials: D
authors.lastname: Singha
authors.affiliation: Midnapore Medical College and Hospital, Vidyasagar Road, Medinipur, West Bengal 721101, India.
authors.forename: Balaram
authors.initials: B
authors.lastname: Ghosh
authors.affiliation: NSHM Knowledge Campus Kolkata, Group of Institutions, 124-BL Saha Road, Kolkata, West Bengal 700053, India. Electronic address: souvikroy35@gmail.com.
authors.forename: Souvik
authors.initials: S
authors.lastname: Roy
mesh_terms: D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry; D002614:Chelating Agents / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic; D016166:Free Radical Scavengers / Q000737:chemistry; D008274:Magnesium / Q000737:chemistry* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008855:Microscopy, Electron, Scanning; D010851:Picrates / Q000737:chemistry; D011794:Quercetin / Q000737:chemistry* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D002614:Chelating Agents; D016166:Free Radical Scavengers; D010851:Picrates; D011794:Quercetin; C004931:1,1-diphenyl-2-picrylhydrazyl; D008274:Magnesium
keywords: Antioxidant activity; Flavonoids; Quercetin; Quercetin–magnesium complex; Radical scavenging activity; Spectral characterisation