title: Sterile Corneal Infiltrates Secondary to Psoriasis Exacerbations: Topical Tacrolimus as an Alternative Treatment Option.
abstract: BACKGROUND
  Psoriasis is a common chronic inflammatory skin disease. Ocular manifestations, which occur in 10% to 20% of cases of psoriasis, are usually bilateral and often present during an exacerbation of the psoriasis. Serious corneal involvement is rare but can be devastating.
  
  
  METHODS
  Two cases of sterile corneal infiltrates secondary to an exacerbation of psoriasis are presented. Treatment involved the use of 0.02% topical tacrolimus ointment, which resulted in resolution of the symptoms and infiltrates.
  
  
  CONCLUSIONS
  Topical tacrolimus may be considered as an alternative treatment option to corticosteroids in sterile corneal infiltrates.
authors.affiliation: Ophthalmology Service (M.G.-A., J.L.G.-S., M.d.C.G.G.), San Cecilio University Hospital, Granada, Spain; Dermatology Service (S.A.-S.), San Cecilio University Hospital, Granada, Spain; Flinders University (C.M.), Adelaide, Australia; and Wenzhou Medical College (C.M.), Wenzhou, China.
authors.forename: Miguel
authors.initials: M
authors.lastname: Gonzalez-Andrades
authors.forename: Salvador
authors.initials: S
authors.lastname: Arias-Santiago
authors.forename: José Luis
authors.initials: JL
authors.lastname: García-Serrano
authors.forename: María Del Carmen
authors.initials: MD
authors.lastname: González Gallardo
authors.forename: Colm
authors.initials: C
authors.lastname: McAlinden
mesh_terms: D000287:Administration, Topical; D000328:Adult; D003316:Corneal Diseases / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D009824:Ointments; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy*; D016559:Tacrolimus / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus