title: Safety of warfarin therapy during cataract surgery under topical anesthesia.
abstract: OBJECTIVE
  To analyze the safety of warfarin therapy during cataract surgery under topical anesthesia.
  
  
  METHODS
  This was a prospective nonrandomized comparative study of 60 eyes of 60 patients treated with or without concurrent oral warfarin anticoagulant therapy, referred for cataract surgery under topical anesthesia. The sample included a treatment (n=30) and a control (n=30) group.
  
  
  RESULTS
  There were no records of intraoperative or postoperative intracameral bleeding complications in both the groups. At 1-month postoperative follow-up, 90.0% of patients presented spectacle-corrected visual acuity of at least 20/40.
  
  
  CONCLUSIONS
  Cataract surgery by phacoemulsification with topical anesthesia can be successfully conducted without discontinuing warfarin.
authors.affiliation: Department of Ophthalmology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Newton
authors.initials: N
authors.lastname: Kara-Junior
authors.affiliation: Department of Ophthalmology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Marcony R
authors.initials: MR
authors.lastname: Santhiago
authors.affiliation: Department of Ophthalmology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Hirlana Gomes
authors.initials: HG
authors.lastname: Almeida
authors.affiliation: Department of Ophthalmology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Ana Carolina
authors.initials: AC
authors.lastname: Raiza
mesh_terms: D000284:Administration, Oral; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000008:administration & dosage; D000925:Anticoagulants / Q000008:administration & dosage*; D002387:Cataract Extraction / Q000009:adverse effects / Q000379:methods*; D005130:Eye Hemorrhage / Q000139:chemically induced; D005500:Follow-Up Studies; D006801:Humans; D019934:International Normalized Ratio / Q000379:methods; D007432:Intraoperative Period; D019654:Lens Implantation, Intraocular; D019106:Postoperative Hemorrhage / Q000139:chemically induced; D011446:Prospective Studies; D014792:Visual Acuity; D014859:Warfarin / Q000008:administration & dosage*
chemical_list: D000779:Anesthetics, Local; D000925:Anticoagulants; D014859:Warfarin