title: Dysplastic Cerebellar Epilepsy: Complete Seizure Control Following Resection of a Ganglioglioma.
abstract: Subcortical epilepsy has been a controversial issue, partially settled by evidence showing seizure generation in hypothalamic hamartomas and also by reports of seizures caused by cerebellar lesions. We report 4-year-old girl with right hemifacial seizures and autonomic phenomena, in whom MRI showed an irregular mass in the right cerebellar peduncle. Despite several unremarkable video-EEG recordings, seizure origin in the lesion was hypothesized. Complete resection was feasible, histopathology showed a ganglioglioma, and she has been seizure free for 3 years. A fine line separates these developmental tumors from focal cortical dysplasia, and the homogeneous presentation of this entity led us to propose the terminology dysplastic cerebellar epilepsy.
authors.affiliation: Severe Epilepsies Outpatient Clinic, Neurology Service, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Avenida Ipiranga 6690, 90610-000, Porto Alegre, RS, Brazil. walvesm.br@gmail.com.|Porto Alegre Epilepsy Surgery Program, Neurology and Neurosurgery Services, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil. walvesm.br@gmail.com.
authors.forename: William Alves
authors.initials: WA
authors.lastname: Martins
authors.affiliation: Porto Alegre Epilepsy Surgery Program, Neurology and Neurosurgery Services, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.|Department of Surgery, Faculty of Medicine, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
authors.forename: Eliseu
authors.initials: E
authors.lastname: Paglioli
authors.affiliation: Severe Epilepsies Outpatient Clinic, Neurology Service, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Avenida Ipiranga 6690, 90610-000, Porto Alegre, RS, Brazil.|Porto Alegre Epilepsy Surgery Program, Neurology and Neurosurgery Services, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
authors.forename: Marta
authors.initials: M
authors.lastname: Hemb
authors.affiliation: Severe Epilepsies Outpatient Clinic, Neurology Service, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Avenida Ipiranga 6690, 90610-000, Porto Alegre, RS, Brazil.|Porto Alegre Epilepsy Surgery Program, Neurology and Neurosurgery Services, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.|Department of Internal Medicine/Neurology, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
authors.forename: Andre
authors.initials: A
authors.lastname: Palmini
mesh_terms: D002528:Cerebellar Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D002531:Cerebellum / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D002675:Child, Preschool; D004827:Epilepsy / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D018303:Ganglioglioma / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D012640:Seizures / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome
keywords: Cerebellar epilepsy; Epilepsy surgery; Ganglioglioma; Hemifacial spasms; Posterior fossa tumor