title: The use of colonic and anorectal high-resolution manometry and its place in clinical work and in research.
abstract: BACKGROUND
  In the esophagus, high-resolution manometry (HRM) has become a standard diagnostic tool in the investigation of suspected motility disorders. However, at the opposite end of the digestive tract (i.e., the colon and anorectum), the use of HRM still remains in its infancy, with relatively few published studies in the scientific literature. Further, the clinical utility of those studies that have been performed is largely undetermined.
  
  
  OBJECTIVE
  This review assesses all of the HRM studies published to date from both the colon and anorectum, explores the catheter types used, and attempts to determine the worth of HRM over traditional 'low-resolution' recordings from the same regions. Ultimately, this review addresses whether HRM currently provides information that will benefit patient diagnosis and treatment.
authors.affiliation: Department of Surgery and Gastroenterology, Flinders Medical Centre, Flinders University, Adelaide, SA, Australia.
authors.forename: P G
authors.initials: PG
authors.lastname: Dinning
authors.affiliation: National Centre for Bowel Research and Surgical Innovation and the GI Physiology Unit, Queen Mary University of London, London, UK.
authors.forename: E V
authors.initials: EV
authors.lastname: Carrington
authors.affiliation: National Centre for Bowel Research and Surgical Innovation and the GI Physiology Unit, Queen Mary University of London, London, UK.
authors.forename: S M
authors.initials: SM
authors.lastname: Scott
mesh_terms: D005762:Gastroenterology / Q000379:methods; D005767:Gastrointestinal Diseases / Q000175:diagnosis*; D006801:Humans; D008365:Manometry / Q000379:methods*
keywords: anorectum; colon; diagnostic; high-resolution manometry