title: Oral Everolimus for Treatment of a Giant Left Ventricular Rhabdomyoma in a Neonate-Rapid Tumor Regression Documented by Real Time 3D Echocardiography.
abstract: The presented case reports on successful treatment with everolimus in a neonate with left ventricular giant rhabdomyoma. The authors used a different dosage regime compared to literature and documented rapid tumor regression by 3D echocardiography.
authors.affiliation: Department of Pediatric Cardiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Robert
authors.initials: R
authors.lastname: Wagner
authors.affiliation: Department of Pediatric Cardiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Frank Thomas
authors.initials: FT
authors.lastname: Riede
authors.affiliation: Department of Cardiac Surgery, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Seki
authors.affiliation: Department of Pediatric Neurology, University of Leipzig, Leipzig, Germany.
authors.forename: Frauke
authors.initials: F
authors.lastname: Hornemann
authors.affiliation: Department of Pediatric Neurology, University of Leipzig, Leipzig, Germany.
authors.forename: Steffen
authors.initials: S
authors.lastname: Syrbe
authors.affiliation: Department of Pediatric Cardiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Ingo
authors.initials: I
authors.lastname: Daehnert
authors.affiliation: Department of Pediatric Cardiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Weidenbach
mesh_terms: D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000008:administration & dosage; D003199:Computer Systems; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D000068338:Everolimus / Q000008:administration & dosage*; D006338:Heart Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy; D012074:Remission Induction / Q000379:methods; D012207:Rhabdomyoma / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D000068338:Everolimus
keywords: cardiac tumor; congenital heart diseases; left ventricular outflow obstruction; real time imaging techniques; three-dimensional transthoracic echocardiography