title: Anti-Bioadhesive Coating Based on Easy to Make Pseudozwitterionic RAFT Block Copolymers for Blood-Contacting Applications.
abstract: Amphiphilic diblock copolymer containing randomly distributed positive and negative charged monomers are synthesized using RAFT polymerization technique to be used as anti-bioadhesion coatings for hydrophobic surfaces. Quaternized 2-(dimethylamino) ethyl methacrylate and potassium 3-sulfopropyl methacrylate (P[qDMAEMA-co-KSPMA]) are randomly polymerized to yield an anti-bioadhesion block which is, in one pot, copolymerized with styrene as an anchoring block. This copolymer has demonstrated high anti-bioadhesion properties to avoid the blood clotting in medical devices through a simple and facile approach to preparation of pseudozwitterionic copolymers.
authors.affiliation: IEM (Institut Europeen des Membranes), UMR 5635 (CNRS-ENSCM-UM2), Universite Montpellier, CC047, Place E. Bataillon, 34095 Montpellier, France.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Nehache
authors.affiliation: R&D Center for Membrane Technology and Department of Chemical Engineering, Chung Yuan Christian University, Jhong-Li, Taoyuan 320, Taiwan.
authors.forename: Chin-Cheng
authors.initials: CC
authors.lastname: Yeh
authors.affiliation: IEM (Institut Europeen des Membranes), UMR 5635 (CNRS-ENSCM-UM2), Universite Montpellier, CC047, Place E. Bataillon, 34095 Montpellier, France.
authors.forename: Mona
authors.initials: M
authors.lastname: Semsarilar
authors.affiliation: IEM (Institut Europeen des Membranes), UMR 5635 (CNRS-ENSCM-UM2), Universite Montpellier, CC047, Place E. Bataillon, 34095 Montpellier, France.
authors.forename: André
authors.initials: A
authors.lastname: Deratani
authors.affiliation: R&D Center for Membrane Technology and Department of Chemical Engineering, Chung Yuan Christian University, Jhong-Li, Taoyuan 320, Taiwan. ychang@cycu.edu.tw.
authors.forename: Yung
authors.initials: Y
authors.lastname: Chang
authors.affiliation: IEM (Institut Europeen des Membranes), UMR 5635 (CNRS-ENSCM-UM2), Universite Montpellier, CC047, Place E. Bataillon, 34095 Montpellier, France. damien.quemener@umontpellier.fr.
authors.forename: Damien
authors.initials: D
authors.lastname: Quemener
mesh_terms: D000327:Adsorption; D001769:Blood; D020099:Coated Materials, Biocompatible; D006801:Humans; D008689:Methacrylates / Q000737:chemistry; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D020058:Styrene / Q000737:chemistry
chemical_list: C529206:3-sulfopropyl methacrylate; D020099:Coated Materials, Biocompatible; D008689:Methacrylates; D011108:Polymers; D020058:Styrene; C049840:2-(dimethylamino)ethyl methacrylate
keywords: RAFT; anti-bioadhesion; blood protein; copolymer; pseudozwitterionic