title: 24-hour human urine and serum profiles of bisphenol A following ingestion in soup: Individual pharmacokinetic data and emographics.
abstract: Here we present data to evaluate potential absorption of Bisphenol A through non-metabolizing tissues of the upper digestive tract. Concurrent serum and urine concentrations of d6-BPA, and its glucuronide and sulfate conjugates, were measured over a 24 h period in 10 adult male volunteers following ingestion of 30 μg d6-BPA/kg body weight in soup. The pharmacokinetic behavior of BPA and its metabolites in this cohort (rapid absorption, complete elimination, evidence against sublingual absorption) was reported. This Data in Brief article contains the corresponding individual pharmacokinetic data, reports the demographics of the cohort and provides additional details related to the analytical methods employed and is related to [4].
authors.affiliation: Health Effects and Exposure Science, Pacific Northwest National Laboratory, Richland, WA 99352, USA ; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 93771, USA.
authors.forename: Justin G
authors.initials: JG
authors.lastname: Teeguarden
authors.affiliation: Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
authors.forename: Nathan C
authors.initials: NC
authors.lastname: Twaddle
authors.affiliation: Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
authors.forename: Mona I
authors.initials: MI
authors.lastname: Churchwell
authors.affiliation: Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
authors.forename: Xiaoxia
authors.initials: X
authors.lastname: Yang
authors.affiliation: Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Fisher
authors.affiliation: Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH 43210, USA.
authors.forename: Liesel M
authors.initials: LM
authors.lastname: Seryak
authors.affiliation: Division of Biochemical Toxicology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Doerge