title: Primary intestinal lymphangiectasia with generalized warts.
abstract: Primary intestinal lymphangiectasia (PIL) is a rare protein-losing enteropathy with lymphatic leakage into the small intestine. Dilated lymphatics in the small intestinal wall and mesentery are observed in this disease. Laboratory tests of PIL patients revealed hypoalbuminemia, lymphocytopenia, hypogammaglobulinemia and increased stool α-1 antitrypsin clearance. Cell-mediated immunodeficiency is also present in PIL patients because of loss of lymphocytes. As a result, the patients are vulnerable to chronic viral infection and lymphoma. However, cases of PIL with chronic viral infection, such as human papilloma virus-induced warts, are rarely reported. We report a rare case of PIL with generalized warts in a 36-year-old male patient. PIL was diagnosed by capsule endoscopy and colonoscopic biopsy with histological tissue confirmation. Generalized warts were observed on the head, chest, abdomen, back, anus, and upper and lower extremities, including the hands and feet of the patient.
authors.affiliation: Soon Jae Lee, Hyun Joo Song, Sun-Jin Boo, Soo-Young Na, Heung Up Kim, Department of Internal Medicine, Jeju National University School of Medicine, Jeju 690-767, South Korea.
authors.forename: Soon Jae
authors.initials: SJ
authors.lastname: Lee
authors.affiliation: Soon Jae Lee, Hyun Joo Song, Sun-Jin Boo, Soo-Young Na, Heung Up Kim, Department of Internal Medicine, Jeju National University School of Medicine, Jeju 690-767, South Korea.
authors.forename: Hyun Joo
authors.initials: HJ
authors.lastname: Song
authors.affiliation: Soon Jae Lee, Hyun Joo Song, Sun-Jin Boo, Soo-Young Na, Heung Up Kim, Department of Internal Medicine, Jeju National University School of Medicine, Jeju 690-767, South Korea.
authors.forename: Sun-Jin
authors.initials: SJ
authors.lastname: Boo
authors.affiliation: Soon Jae Lee, Hyun Joo Song, Sun-Jin Boo, Soo-Young Na, Heung Up Kim, Department of Internal Medicine, Jeju National University School of Medicine, Jeju 690-767, South Korea.
authors.forename: Soo-Young
authors.initials: SY
authors.lastname: Na
authors.affiliation: Soon Jae Lee, Hyun Joo Song, Sun-Jin Boo, Soo-Young Na, Heung Up Kim, Department of Internal Medicine, Jeju National University School of Medicine, Jeju 690-767, South Korea.
authors.forename: Heung Up
authors.initials: HU
authors.lastname: Kim
authors.affiliation: Soon Jae Lee, Hyun Joo Song, Sun-Jin Boo, Soo-Young Na, Heung Up Kim, Department of Internal Medicine, Jeju National University School of Medicine, Jeju 690-767, South Korea.
authors.forename: Chang Lim
authors.initials: CL
authors.lastname: Hyun
mesh_terms: D000328:Adult; D001706:Biopsy; D053704:Capsule Endoscopy; D002908:Chronic Disease; D003113:Colonoscopy; D018752:Diet, Fat-Restricted; D004044:Dietary Proteins / Q000008:administration & dosage; D006801:Humans; D016867:Immunocompromised Host; D007150:Immunohistochemistry; D008201:Lymphangiectasis, Intestinal / Q000150:complications* / Q000175:diagnosis / Q000178:diet therapy / Q000276:immunology; D008209:Lymphedema / Q000150:complications* / Q000175:diagnosis / Q000178:diet therapy / Q000276:immunology; D008297:Male; D009894:Opportunistic Infections / Q000175:diagnosis / Q000276:immunology / Q000821:virology*; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000276:immunology / Q000821:virology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014280:Triglycerides / Q000008:administration & dosage; D014860:Warts / Q000175:diagnosis / Q000276:immunology / Q000821:virology*
chemical_list: D004044:Dietary Proteins; D014280:Triglycerides
keywords: Cell-mediated immunodeficiency; Lymphocytopenia; Primary intestinal lymphangiectasia; Protein-losing enteropathy; Warts