title: Changes in Oxygen Partial Pressure in the Vitreous Body and Arterial Blood of Rabbits Depending on Oxygen Concentration in Inspired Mixture.
abstract: We demonstrated that the vitreous body of one-month-old rabbits becomes a "reservoir" for storage and accumulation of oxygen after exposure to additional oxygenation of the organism (O2 concentrations in inspired gas mixture were 40, 60, 85, and 99%). The higher was O2 concentration in inspired mixture, the higher was oxygen saturation of the blood and vitreous body. O2 concentration of 40% was relatively safe for eye tissues. O2 concentration >60% induced oxygen accumulation in the vitreous body, which can be a provoking factor for the development of oxygen-induced pathologies.
authors.affiliation: Department of Ophthalmology, Faculty of Pediatrics, N. I. Pirogov Russian National Research Medical University, Moscow, Russia, eidos_eidosovich@mail.ru.
authors.forename: L I
authors.initials: LI
authors.lastname: Amkhanitskaya
authors.forename: G V
authors.initials: GV
authors.lastname: Nikolaeva
authors.forename: N A
authors.initials: NA
authors.lastname: Sokolova
mesh_terms: D000818:Animals; D008297:Male; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology; D010313:Partial Pressure; D011817:Rabbits; D014822:Vitreous Body / Q000378:metabolism*
chemical_list: D010100:Oxygen