title: Safety Assessment of Galactomannans as Used in Cosmetics.
abstract: The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of 16 galactomannans as used in cosmetics. These ingredients are legume polysaccharides that function mostly as hair/skin-conditioning agents and viscosity-increasing agents in cosmetic products. Their substantial molecular sizes suggest that skin penetration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment.
authors.affiliation: Cosmetic Ingredient Review Senior Scientific Analyst/Writer, Washington DC, WA, USA.
authors.forename: Wilbur
authors.initials: W
authors.lastname: Johnson
authors.affiliation: Cosmetic Ingredient Review, Chemist, Washington DC, WA, USA.
authors.forename: Bart
authors.initials: B
authors.lastname: Heldreth
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: Wilma F
authors.initials: WF
authors.lastname: Bergfeld
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: Donald V
authors.initials: DV
authors.lastname: Belsito
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: Ronald A
authors.initials: RA
authors.lastname: Hill
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: Curtis D
authors.initials: CD
authors.lastname: Klaassen
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Liebler
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: James G
authors.initials: JG
authors.lastname: Marks
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: Ronald C
authors.initials: RC
authors.lastname: Shank
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Slaga
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, WA, USA.
authors.forename: Paul W
authors.initials: PW
authors.lastname: Snyder
authors.affiliation: Former Director, Cosmetic Ingredient Review, Washington, DC, WA, USA.
authors.forename: F Alan
authors.initials: FA
authors.lastname: Andersen
mesh_terms: D000485:Allergens / Q000633:toxicity; D000818:Animals; D029911:Caesalpinia / Q000633:toxicity*; D015197:Carcinogenicity Tests; D002366:Cassia / Q000633:toxicity*; D003257:Consumer Product Safety; D003358:Cosmetics / Q000633:toxicity*; D005685:Galactans / Q000633:toxicity*; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D007509:Irritants / Q000633:toxicity; D008351:Mannans / Q000737:chemistry / Q000633:toxicity*; D053149:Plant Gums / Q000633:toxicity*
chemical_list: D000485:Allergens; D003358:Cosmetics; D005685:Galactans; D007509:Irritants; D008351:Mannans; D053149:Plant Gums; C012990:galactomannan; C007894:guar gum; D005690:Galactose
keywords: cosmetics; galactomannans; safety