title: Changes in negative implicit evaluations in patients of hypochondriasis after treatment with cognitive therapy or exposure therapy.
abstract: OBJECTIVE
  Previous studies using modified versions of the Affect Misattribution Procedure (AMP; Payne, Cheng, Govorun, & Stewart, 2005) have revealed that there is an implicit negative evaluation bias of illness-related information in patients with hypochondriasis (HYP), which might be a maintaining feature of HYP. However, there is no evidence on whether this bias might be targeted successfully by effective treatments, such as exposure therapy (ET) or cognitive therapy (CT). This is the first study to examine the change in negative implicit evaluations in a randomized controlled trial, including individual CT and ET, compared to a wait-list control group for HYP.
  
  
  METHODS
  An AMP with illness, symptom and neutral primes was used in 70 patients with HYP before and after treatment (wait-list respectively).
  
  
  RESULTS
  There was no significant change in negative implicit affective evaluations in both CT and ET, compared to wait-list. However, comparisons between the two active treatments revealed an interaction effect, that only for CT were the affective reactions on illness-as well as symptom-related prime trials (but not neutral primes) significantly more positive at post-compared to pre-treatment. In CT but not in ET, the reduction of implicit negative evaluation bias regarding symptom-related primes was significantly related to the reduction of self-reported health anxiety.
  
  
  CONCLUSIONS
  The small subsample sizes for CT and ET, in comparison to wait-list, prohibit the detection of smaller effects.
  
  
  CONCLUSIONS
  Formal cognitive restructuring is necessary for reducing implicit negative evaluation bias in HYP, but the latter is not a prerequisite for reducing health anxiety. Thus, the importance of the negative implicit evaluation bias for the maintenance of HYP remains questionable.
authors.affiliation: Department of Clinical Psychology and Psychotherapy, Goethe-University, Frankfurt am Main, Germany. Electronic address: schreiber@psych.uni-frankfurt.de.
authors.forename: Franziska
authors.initials: F
authors.lastname: Schreiber
authors.affiliation: Clinical Psychology, Psychotherapy and Experimental Psychopathology, Johannes Gutenberg University, Mainz, Germany. Electronic address: witthoef@uni-mainz.de.
authors.forename: Michael
authors.initials: M
authors.lastname: Witthöft
authors.affiliation: Department of Clinical Psychology and Psychotherapy, Goethe-University, Frankfurt am Main, Germany. Electronic address: neng@psych.uni-frankfurt.de.
authors.forename: Julia M B
authors.initials: JM
authors.lastname: Neng
authors.affiliation: Clinical Psychology, Psychotherapy and Experimental Psychopathology, Johannes Gutenberg University, Mainz, Germany. Electronic address: flweck@uni-mainz.de.
authors.forename: Florian
authors.initials: F
authors.lastname: Weck
mesh_terms: D000328:Adult; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D006998:Hypochondriasis / Q000628:therapy*; D007171:Implosive Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
keywords: Affect misattribution procedure; Cognitive therapy; Exposure therapy; Health anxiety; Hypochondriasis