title: The virologist and the flu.
abstract: We report a case of a virologist - who is in age-appropriate medical condition with no relevant chronic diseases - who shed influenza A H3N2 virus RNA for 70 days while infectious virus could be detected by cell culture only up to 5 days after onset of symptoms despite a 5-day course of oseltamivir. The case might have implications for infection control in hospital settings and the weighting of the predictive value of PCR results.
authors.affiliation: Occupational Health Service, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Electronic address: Sabine.Wicker@kgu.de.
authors.forename: Sabine
authors.initials: S
authors.lastname: Wicker
authors.affiliation: Institute of Medical Virology, University Hospital Frankfurt, Goethe University, Paul-Ehrlich-Str. 40, 60596 Frankfurt am Main, Germany. Electronic address: Rabenau@em.uni-frankfurt.de.
authors.forename: Holger F
authors.initials: HF
authors.lastname: Rabenau
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D006801:Humans; D053122:Influenza A Virus, H3N2 Subtype / Q000187:drug effects / Q000235:genetics*; D007251:Influenza, Human / Q000188:drug therapy* / Q000821:virology; D008297:Male; D008875:Middle Aged; D053139:Oseltamivir / Q000627:therapeutic use; D012367:RNA, Viral / Q000032:analysis* / Q000187:drug effects; D019562:Viral Load / Q000187:drug effects; D017201:Virus Shedding / Q000187:drug effects*
chemical_list: D000998:Antiviral Agents; D012367:RNA, Viral; D053139:Oseltamivir
keywords: Influenza; Influenza vaccination; Viral shedding