title: The reliability and minimal detectable change of Timed Up and Go test in individuals with grade 1-3 knee osteoarthritis.
abstract: BACKGROUND
  The Timed Up and Go (TUG) test is quick and easy tests to assess patients' functional mobility. However, its reliability in individuals with knee osteoarthritis (OA) has not been well established. The aims of this study were to determine the reliability and minimal detectable change of the TUG test in individuals with doubtful to moderate (Grade 1-3) knee OA.
  
  
  METHODS
  Sixty-five subjects (25 male, 40 female), aged 45-70 years, with knee OA participated. Inter-rater reliability was assessed using two observers at different times of the same day in an alternating order. Intra-rater reliability was assessed on two consecutive visits with a 2-day interval. The standard error of measurement (SEM) and the minimum detectable change (MDC) were calculated to determine statistically meaningful changes.
  
  
  RESULTS
  Intra-rater and inter-rater reliability were 0.97 (95% confidence interval [CI], 0.95 - 0.98) and 0.96 (95% confidence interval [CI], 0.94 - 0.97), respectively. The MDC, based on measurements by a single rater and between raters, was 1.10 and 1.14 seconds, respectively.
  
  
  CONCLUSIONS
  The TUG is a reliable test with adequate MDC for clinical use in individuals with doubtful to moderate knee OA.
authors.affiliation: Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia. aalghadir@hotmail.com.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Alghadir
authors.affiliation: Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia. anwer_shahnawazphysio@rediffmail.com.|Dr. D. Y. Patil College of Physiotherapy, Dr. D. Y. Patil Vidyapeeth, Pune, India. anwer_shahnawazphysio@rediffmail.com.
authors.forename: Shahnawaz
authors.initials: S
authors.lastname: Anwer
authors.affiliation: Center for Rehabilitation Research, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. jm.brismee@ttuhsc.edu.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Brismée
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D051346:Mobility Limitation; D020370:Osteoarthritis, Knee / Q000175:diagnosis* / Q000453:epidemiology; D010147:Pain Measurement / Q000592:standards*; D015203:Reproducibility of Results