title: En face mode of swept-source optical coherence tomography in circumscribed choroidal haemangioma.
abstract: OBJECTIVE
  To describe the findings in circumscribed choroidal haemangioma (CCH) using en face swept-source optical coherence tomography (SS-OCT).
  
  
  METHODS
  En face images were obtained employing DRI-1 Atlantis OCT (Topcon, Tokyo, Japan), using a three-dimensional volumetric scan of 12×9 mm. Images were obtained from the retinal pigment epithelium to 1000 μm in depth of the tumour.
  
  
  RESULTS
  Twenty-two eyes from 22 patients with the clinical diagnosis of CCH were included. In 20 eyes (90.9%), a characteristic pattern was visualised in the en face image across the vascular tumour. A multilobular pattern, similar to a honeycomb, with hyporeflective, confluent, oval or round areas corresponding with the lumen of the tumour vascular spaces, and hyper-reflective zones, which may represent the vessels walls and connective tissue of the tumour. Ten eyes (45.4%) showed a hyper-reflective halo surrounding the tumour. Seventeen tumours (77.2%) showed small diameter vessels at the inner zone and larger vessels in the outer area. Twelve patients (54.5%) had previously received treatment (photodynamic therapy, transpupillary thermotherapy, dexamethasone intravitreal implant or brachytherapy with ruthenium-106). No differences were found between treated and untreated patients in any of the measured parameters.
  
  
  CONCLUSIONS
  En face SS-OCT is a rapid, non-invasive, high-resolution, technology, which allows a complementary study to cross-sectional scans in CCH. A characteristic multilobular pattern, with a hyper-reflective halo surrounding the tumour, was found in en face SS-OCT images. No morphological differences were found between naïve patients and patients who received previous treatment.
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Flores-Moreno
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: Josep M
authors.initials: JM
authors.lastname: Caminal
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Arias-Barquet
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: Marcos J
authors.initials: MJ
authors.lastname: Rubio-Caso
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: Jaume
authors.initials: J
authors.lastname: Catala-Mora
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: María
authors.initials: M
authors.lastname: Vidal-Martí
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: Alex
authors.initials: A
authors.lastname: Muñoz-Blanco
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Filloy
authors.affiliation: Department of Ophthalmology, Castilla La Mancha University, Albacete, Spain.
authors.forename: José M
authors.initials: JM
authors.lastname: Ruiz-Moreno
authors.affiliation: New England Eye Center, Tufts Medical Center, Boston, Massachusetts, USA.
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
authors.affiliation: Department of Ophthalmology, Bellvitge University Hospital, Barcelona, Spain.
authors.forename: Jorge
authors.initials: J
authors.lastname: Arruga
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D002830:Choroid Neoplasms / Q000175:diagnosis* / Q000628:therapy; D003430:Cross-Sectional Studies; D005260:Female; D005451:Fluorescein Angiography; D018324:Hemangioma, Capillary / Q000175:diagnosis* / Q000628:therapy; D006392:Hemangioma, Cavernous / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D010778:Photochemotherapy; D041623:Tomography, Optical Coherence / Q000379:methods*
keywords: Choroid; Imaging; Neoplasia