title: "CRISPR" validation of recessive brain cancer genes in vivo.
authors.affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
authors.forename: Marc
authors.initials: M
authors.lastname: Zuckermann
authors.affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kawauchi
authors.affiliation: Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Gronych
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000235:genetics*; D001932:Brain Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D064130:CRISPR-Associated Proteins / Q000235:genetics / Q000378:metabolism; D064113:CRISPR-Cas Systems; D064112:Clustered Regularly Interspaced Short Palindromic Repeats; D015972:Gene Expression Regulation, Neoplastic; D015723:Gene Library; D005808:Genes, Recessive; D020022:Genetic Predisposition to Disease; D005821:Genetic Techniques; D006801:Humans; D010641:Phenotype
chemical_list: D014408:Biomarkers, Tumor; D064130:CRISPR-Associated Proteins
keywords: CRISPR/Cas9; Chromosome Section; brain tumors; mouse models; somatic gene transfer