title: Effect of pre-treatment with chlorhexidine on the retention of restorations: a randomized controlled trial.
abstract: This study aimed to evaluate the effect of chlorhexidine (CHX) application on etched dentin on the 6-month retention of restorations placed on non-carious cervical lesions (NCCLs). A randomized controlled split-mouth and triple blind trial was carried out. Patients (n=42) with at least two non-carious cervical lesions were included. NCCLs were randomly assigned to two groups: control (placebo solution) or test group (2% CHX solution for 60 s after acid etching and before the adhesive application). Class V restorations (n=169) were performed with an etch-and-rinse adhesive system and composite resin by 10 trained operators. A calibrated examiner evaluated the restorations at 1 week (baseline) and at 6 months using the FDI criteria. The primary outcome was retention of the restorations. The analysis of factors associated to failure of restorations was carried out by Fisher's exact test (α=0.05). After 6 months of follow-up, 3.4% (CI 95% 1.3-7.3) of the restorations failed. There was no statistically significant difference between control and CHX (p=0.920). Regarding the cavity variables, deeper (p=0.04), wider (p=0.004) and wedge-shaped (p=0.033) cavities failed more. Both treatments provided acceptable clinical performance of the restorations. The use of CHX as a adjuvant in dentin adhesion did not influence the retention of Class V restorations after 6 months of follow-up.
authors.affiliation: Department of Restorative Dentistry, Graduate Program in Dentistry, Universidade Federal de Pelotas, Pelotas, RS, Brasil.
authors.forename: Anelise Fernandes
authors.initials: AF
authors.lastname: Montagner
authors.affiliation: Department of Restorative Dentistry, Graduate Program in Dentistry, Universidade Federal de Pelotas, Pelotas, RS, Brasil.
authors.forename: Ana Paula
authors.initials: AP
authors.lastname: Perroni
authors.affiliation: Department of Restorative Dentistry, Graduate Program in Dentistry, Universidade Federal de Pelotas, Pelotas, RS, Brasil.
authors.forename: Marcos Britto
authors.initials: MB
authors.lastname: Corrêa
authors.affiliation: Department of Restorative Dentistry, Graduate Program in Dentistry, Universidade Federal de Pelotas, Pelotas, RS, Brasil.
authors.forename: Alexandre Severo
authors.initials: AS
authors.lastname: Masotti
authors.affiliation: Department of Restorative Dentistry, Graduate Program in Dentistry, Universidade Federal de Pelotas, Pelotas, RS, Brasil.
authors.forename: Tatiana
authors.initials: T
authors.lastname: Pereira-Cenci
authors.affiliation: Department of Restorative Dentistry, Graduate Program in Dentistry, Universidade Federal de Pelotas, Pelotas, RS, Brasil.
authors.forename: Maximiliano Sérgio
authors.initials: MS
authors.lastname: Cenci
mesh_terms: D000134:Acid Etching, Dental; D002710:Chlorhexidine / Q000008:administration & dosage*; D003738:Dental Cements; D003793:Dental Restoration, Permanent; D006801:Humans; D010919:Placebos
chemical_list: D003738:Dental Cements; D010919:Placebos; D002710:Chlorhexidine