title: Data from a proteomic analysis of colonic fibroblasts secretomes.
abstract: The tumor cell proliferation, migration and invasion were influenced by the interaction between the cancer cells and their microenvironment. In current study, we established two pairs of the primary fibroblast cultures from colorectal adenocarcinoma tissues and the normal counterparts and identified 227 proteins in the colonic fibroblast secretomes; half of these proteins were novel. The mass spectrometry data and analyzed results presented here provide novel insights into the molecular characteristics and modulatory role of colon cancer associated fibroblasts. The data is related to "Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation" by Chen et al. [1].
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Sun-Xia
authors.initials: SX
authors.lastname: Chen
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Xiao-En
authors.initials: XE
authors.lastname: Xu
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Wang
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Shu-Jian
authors.initials: SJ
authors.lastname: Cui
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Lei-Lei
authors.initials: LL
authors.lastname: Xu
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Ying-Hua
authors.initials: YH
authors.lastname: Jiang
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Hai-Bo
authors.initials: HB
authors.lastname: Yan
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Qiao
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Peng-Yuan
authors.initials: PY
authors.lastname: Yang
authors.affiliation: Department of Medical Systems Biology of School of Basic Medical Sciences and Institutes of Biomedical Sciences, Fudan University, 131 Dongan Road, Shanghai 200032, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Liu
keywords: Cancer-associated fibroblast; Colorectal cancer; Follistatin-related protein 1; Proteomics; Secretome; Tumor microenvironment