title: Individualized Surgical Templates and Titanium Microplates for Le Fort I Osteotomy by Computer-Aided Design and Computer-Aided Manufacturing.
abstract: The authors report the use of novel individualized surgical templates and titanium miniplates for Le Fort I osteotomy and evaluate the accuracy of this technique in vitro. Nine three-dimensional stereolithographic skull models were used to design the templates and titanium microplates and to simulate the operation. Cone beam computed tomography (CBCT) scans of the skulls were acquired preoperatively and were used to generate virtual models. The surgical plans were made based on three-dimensional cephalometric analyses, and osteotomies were then performed virtually. Cylinder-shaped markers were placed to permit the correct location of titanium screws, and individualized surgical templates were designed. The bony segments were then repositioned virtually according to the surgical plans to correct the skeletal deformities. Resin surgical templates were produced by stereolithography rapid prototyping and the titanium miniplates by three-dimensional cutting. Le Fort I osteotomy was performed under the guide of the surgical templates and fixed with the titanium miniplates. Postoperatively, CBCT scans of each skull model were taken, and the differences between the actual and planned surgical outcomes were measured by superimposing the planned and postoperative virtual models generated from CBCT images. The authors demonstrated that the average linear difference between the planned and actual outcomes was <1 mm and the average orientation difference was <1°. The individualized surgical templates and titanium microplates designed in this experimental study permitted the repositioning of the maxillary segment to the correct planned positions during Le Fort I osteotomy, making this technique a promising alternative to the conventional split method.
authors.affiliation: *Department of Oral and Maxillofacial Surgery †Department of Oral and Maxillofacial Radiology, Peking University School and Hospital of Stomatology, Beijing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: He
authors.forename: Kaiyue
authors.initials: K
authors.lastname: Tian
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Xie
authors.forename: Xiaoxia
authors.initials: X
authors.lastname: Wang
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.forename: Xing
authors.initials: X
authors.lastname: Wang
authors.forename: Zili
authors.initials: Z
authors.lastname: Li
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D001860:Bone Plates; D002508:Cephalometry / Q000379:methods; D017076:Computer-Aided Design; D054893:Cone-Beam Computed Tomography / Q000379:methods; D005240:Feasibility Studies; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008437:Maxilla / Q000033:anatomy & histology / Q000601:surgery*; D008904:Miniaturization; D008953:Models, Anatomic; D019340:Osteotomy, Le Fort / Q000295:instrumentation* / Q000379:methods; D010347:Patient Care Planning; D012117:Resins, Synthetic / Q000737:chemistry; D012886:Skull / Q000033:anatomy & histology; D025321:Surgery, Computer-Assisted / Q000379:methods; D014025:Titanium / Q000737:chemistry*; D016896:Treatment Outcome; D014584:User-Computer Interface
chemical_list: D001672:Biocompatible Materials; D012117:Resins, Synthetic; D014025:Titanium