title: ARE THERE ANY PARTICULARITIES IN CROHN'S DISEASE IN NORTH-EASTERN ROMANIA?
abstract: Crohn's disease is an inflammatory disease of the gastro-intestinal tract with an evolution marked by activity and remission periods. Lately, the incidence and evolution models of Crohn's disease significantly changed, an increasing number of patients presenting more severe forms. The aim of the study is to analyze Crohn's disease in its phenotypic classification and to establish correlation between the localization, the behavior and the activity of Crohn's disease.
  
  
  METHODS
  A transversal study on 53 patients with Crohn's disease was conducted.
  
  
  RESULTS
  from the 53 patients, 56.6% were males, 85% from the urban areas. Under the phenotype aspect, the colonic localization (49.1%) and the inflammatory behavior (52.8%) were predominant. More severe forms of activity were discovered to patients with ileal localization (57.1%) or with penetrant phenotype (33.3%).
  
  
  CONCLUSIONS
  Male patients from urban areas were predominant. The most frequent forms are the colonic and ileocolonic forms. From a behavioral point of view, we observed an obvious predominance of the inflammatory phenotype. The moderate--severe activity was predominant for the ileal localization and the mild-- moderate activity for the colonic and ileocolonic localization. A mild--moderate activity is present for the stenosing forms and a moderate--severe one for the penetrant forms.
authors.forename: Mihaela
authors.initials: M
authors.lastname: Dranga
authors.forename: Cătălina
authors.initials: C
authors.lastname: Mihai
authors.forename: Otilia
authors.initials: O
authors.lastname: Gavrilescu
authors.forename: Cristina Cijevschi
authors.initials: CC
authors.lastname: Prelipcean
mesh_terms: D000328:Adult; D000368:Aged; D003106:Colon / Q000473:pathology*; D003424:Crohn Disease / Q000175:diagnosis* / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D006801:Humans; D007082:Ileum / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D012424:Rural Population / Q000706:statistics & numerical data*; D012720:Severity of Illness Index; D017678:Sex Distribution; D014505:Urban Population / Q000706:statistics & numerical data*