title: Creating value with financially adaptive clinical trials.
authors.affiliation: Pharmagellan, 499 Adams Street, Box 94, Milton, Massachusetts 02186, USA.
authors.forename: Frank S
authors.initials: FS
authors.lastname: David
authors.affiliation: Ernst &Young LLP, 1 Battery Place, New York, New York 10004, USA.
authors.forename: Sarah
authors.initials: S
authors.lastname: Bobulsky
authors.affiliation: Autonomous Tractor Corporation, 4302 13th Avenue South, Fargo, North Dakota 58103, USA.
authors.forename: Kraig
authors.initials: K
authors.lastname: Schulz
authors.affiliation: Cytel Inc., 675 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.
authors.forename: Nitin
authors.initials: N
authors.lastname: Patel
mesh_terms: D002986:Clinical Trials as Topic / Q000191:economics* / Q000379:methods; D004345:Drug Industry / Q000191:economics*; D006801:Humans; D012106:Research / Q000191:economics* / Q000458:organization & administration; D012107:Research Design; D012306:Risk