title: Identifying Obstructive Sleep Apnea in Administrative Data: A Study of Diagnostic Accuracy.
abstract: BACKGROUND
  Health administrative (HA) databases are increasingly used to identify surgical patients with obstructive sleep apnea (OSA) for research purposes, primarily using diagnostic codes. Such means to identify patients with OSA are not validated. The authors determined the accuracy of case-ascertainment algorithms for identifying patients with OSA with the use of HA data.
  
  
  METHODS
  Clinical data derived from an academic health sciences network within a universal health insurance plan were used as the reference standard. The authors linked patients to HA data and retrieved all claims in the 2 yr before surgery to determine the presence of any diagnostic codes, diagnostic procedures, or therapeutic interventions consistent with OSA.
  
  
  RESULTS
  The authors identified 4,965 patients (2003 to 2012) who underwent preoperative polysomnogram. Of these, 4,353 patients were linked to HA data; 2,427 of these (56%) had OSA based on diagnosis by a sleep physician or the apnea hypopnea index. A claim for a polysomnogram and receipt of a positive airway pressure device had a sensitivity, specificity, and positive likelihood ratio (+LR) for OSA of 19, 98, and 10.9%, respectively. An International Classification of Diseases, Tenth Revision, code for sleep apnea in hospitalization abstracts was 9% sensitive and 98% specific (+LR, 4.5). A physician billing claim for OSA (International Classification of Diseases, Ninth Revision, 780.5) was 58% sensitive and 38% specific (+LR, 0.9). A polysomnogram and a positive airway pressure device or any code for OSA was 70% sensitive and 36% specific (+LR, 1.1).
  
  
  CONCLUSIONS
  No code or combination of codes provided a +LR high enough to adequately identify patients with OSA. Existing studies using administrative codes to identify OSA should be interpreted with caution.
authors.affiliation: From the Department of Anesthesiology, University of Ottawa, Department of Anesthesiology, The Ottawa Hospital, and Institute for Clinical Evaluative Sciences at uOttawa, Ottawa, Ontario, Canada (D.I.M.); Sunnybrook Health Sciences Centre, Institute for Clinical Evaluative Sciences, and University of Toronto, Toronto, Ontario, Canada (A.G.); Li Ka Shing Knowledge Institute of St. Michael's Hospital, Department of Anesthesia and Pain Management, Toronto General Hospital, Department of Anesthesia and Institute of Health Policy Management and Evaluation, University of Toronto, and Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada (D.W.); Department of Anesthesiology, University of Ottawa, and Department of Anesthesiology, The Ottawa Hospital, Ottawa, Ontario, Canada (G.L.B.); Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, and Kelowna General Hospital, Kelowna, British Columbia, Canada (N.B.); and Department of Medicine, University of Ottawa, and Institute for Clinical Evaluative Sciences at uOttawa, Ottawa, Ontario, Canada (C.v.W.).
authors.forename: Daniel I
authors.initials: DI
authors.lastname: McIsaac
authors.forename: Andrea
authors.initials: A
authors.lastname: Gershon
authors.forename: Duminda
authors.initials: D
authors.lastname: Wijeysundera
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Bryson
authors.forename: Neal
authors.initials: N
authors.lastname: Badner
authors.forename: Carl
authors.initials: C
authors.lastname: van Walraven
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D016208:Databases, Factual / Q000592:standards* / Q000706:statistics & numerical data; D005260:Female; D006739:Hospital Administration / Q000592:standards* / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D009864:Ontario / Q000453:epidemiology; D017286:Polysomnography / Q000592:standards; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000453:epidemiology*