title: Nano-copper catalysed highly regioselective synthesis of 2,4-disubstituted pyrroles from terminal alkynes and isocyanides.
abstract: Nano-copper(0) stabilized on alumina prepared from Cu-Al hydrotalcite has been reported for completely regioselective synthesis of 2,4-disubstituted pyrroles from unactivated terminal aromatic/aliphatic alkynes and isocyanides. The reaction is operationally simple, involves ligand-free inexpensive nano-copper, and affords products in high yields.
authors.affiliation: Inorganic and Physical Division CSIR-Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad 500607, India. dktiwari@iict.res.in plikhar@iict.res.in.
authors.forename: Dipak Kumar
authors.initials: DK
authors.lastname: Tiwari
authors.forename: Jaya
authors.initials: J
authors.lastname: Pogula
authors.forename: B
authors.initials: B
authors.lastname: Sridhar
authors.forename: Dharmendra Kumar
authors.initials: DK
authors.lastname: Tiwari
authors.forename: Pravin R
authors.initials: PR
authors.lastname: Likhar
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000536:Aluminum Hydroxide / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003486:Cyanides / Q000737:chemistry*; D008276:Magnesium Hydroxide / Q000737:chemistry*; D015394:Molecular Structure; D036103:Nanotechnology; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D003486:Cyanides; D011758:Pyrroles; C010467:hydrotalcite; D000536:Aluminum Hydroxide; D003300:Copper; D008276:Magnesium Hydroxide