title: Green tea extract decreases starch digestion and absorption from a test meal in humans: a randomized, placebo-controlled crossover study.
abstract: Green tea is known worldwide for its beneficial effects on human health. However, objective data evaluating this influence in humans is scarce. The aim of the study was to assess the impact of green tea extract (GTE) on starch digestion and absorption. The study comprised of 28 healthy volunteers, aged 19 to 28 years. In all subjects, a starch (13)C breath test was performed twice. Subjects randomly ingested naturally (13)C-abundant cornflakes during the GTE test (GTE 4 g) or placebo test. The cumulative percentage dose recovery (CPDR) was significantly lower for the GTE test than for the placebo test (median [interquartile range]: 11.4% [5.5-15.5] vs. 16.1% [12.7-19.5]; p = 0.003). Likewise, CPDR expressed per hour was considerably lower in each point of the measurement. In conclusion, a single dose of green tea extract taken with a test meal decreases starch digestion and absorption.
authors.affiliation: Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Klaudia
authors.initials: K
authors.lastname: Lochocka
authors.affiliation: Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Poznan, Poland.
authors.forename: Joanna
authors.initials: J
authors.lastname: Bajerska
authors.affiliation: Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Glapa
authors.affiliation: Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Fidler-Witon
authors.affiliation: Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Jan K
authors.initials: JK
authors.lastname: Nowak
authors.affiliation: Department of Neonatology, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Szczapa
authors.affiliation: Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Philip
authors.initials: P
authors.lastname: Grebowiec
authors.affiliation: Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Lisowska
authors.affiliation: Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Jaroslaw
authors.initials: J
authors.lastname: Walkowiak
mesh_terms: D000328:Adult; D015992:Body Mass Index; D001944:Breath Tests; D002247:Carbon Isotopes / Q000737:chemistry / Q000378:metabolism; D018592:Cross-Over Studies; D004063:Digestion / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D015990:Placebo Effect; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D013213:Starch / Q000378:metabolism*; D013662:Tea / Q000737:chemistry* / Q000378:metabolism; D055815:Young Adult
chemical_list: D002247:Carbon Isotopes; D010936:Plant Extracts; D013662:Tea; D013213:Starch