title: The Japanese version of the Rapid Dementia Screening Test is effective compared to the clock-drawing test for detecting patients with mild Alzheimer's disease.
abstract: BACKGROUND
  The Japanese version of the Rapid Dementia Screening Test (RDST-J) and the clock-drawing test (CDT) are both brief psychometric screening tools used to detect the severity of Alzheimer's disease. It remains unclear, however, which is more effective when screening for mild Alzheimer's disease.
  
  
  METHODS
  We administered the RDST-J and CDT to 250 patients with very mild to severe Alzheimer's disease and to 49 healthy volunteers. Patients with a Mini-Mental State Examination score of 12-26 had Clinical Dementia Rating (CDR) scores from 0.5 to 3. Patients were divided into four groups according to CDR score. We performed one-way factorial anova between the four groups and control subjects based on the CDT and RDST-J scores.
  
  
  RESULTS
  Data analysis revealed that RDST-J could distinguish patients with CDR 0.5 from the controls, but CDT could not. Furthermore, the sensitivity of a RDST-J score ≥8 was 57.1%, with a specificity of 81.0%, and the sensitivity of a RDST-J score ≥9 was 79.6%, with a specificity of 55.1% for discriminating CDR 0.5 from controls.
  
  
  CONCLUSIONS
  RDST-J is a more effective tool than CDT for distinguishing CDR 0.5 from controls.
authors.affiliation: Psychiatry, Komagino Hospital, Tokyo, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Moriyama
authors.affiliation: Psychiatry, National Defense Medical College, Saitama, Japan.
authors.forename: Aihide
authors.initials: A
authors.lastname: Yoshino
authors.affiliation: Psychiatry, Komagino Hospital, Tokyo, Japan.
authors.forename: Kaori
authors.initials: K
authors.lastname: Yamanaka
authors.affiliation: Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Motoichiro
authors.initials: M
authors.lastname: Kato
authors.affiliation: Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Taro
authors.initials: T
authors.lastname: Muramatsu
authors.affiliation: Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Mimura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000208:ethnology / Q000523:psychology; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000175:diagnosis* / Q000208:ethnology / Q000523:psychology; D003704:Dementia / Q000175:diagnosis* / Q000208:ethnology / Q000523:psychology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D015577:Geriatric Assessment / Q000379:methods; D006801:Humans; D007564:Japan; D008297:Male; D009483:Neuropsychological Tests / Q000592:standards*; D011594:Psychometrics; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
keywords: Alzheimer's disease; Japanese version of the Rapid Dementia Screening Test; category fluency task; clock-drawing test; number-transcoding task