title: Clinical perspectives on mesenchymal stem cells promoting wound healing in diabetes mellitus patients by inducing autophagy.
abstract: The pathogenesis of wound healing in diabetes mellitus is complicated, and results in less effective healing. Mesenchymal stem cells (MSCs) have been thought to promote wound healing in diabetes. However, the underlying mechanisms are not well understood. Autophagy plays an important role in wound healing. It has been speculated that the mesenchymal stem cells derived from the umbilical cord can improve wound healing in diabetes mellitus by inducing autophagy. Hence, we reviewed the research progress in this field to identify new strategies of clinical treatment for wound healing in diabetes mellitus.
authors.affiliation: Department of Plastic Surgery, Affiliated Beijing Shijitan Hospital, Capital Medical University, Beijing, People's Republic of China. lauruatr@163.com.
authors.forename: Y-F
authors.initials: YF
authors.lastname: Han
authors.forename: T-J
authors.initials: TJ
authors.lastname: Sun
authors.forename: Y-Q
authors.initials: YQ
authors.lastname: Han
authors.forename: G
authors.initials: G
authors.lastname: Xu
authors.forename: J
authors.initials: J
authors.lastname: Liu
authors.forename: R
authors.initials: R
authors.lastname: Tao
mesh_terms: D000818:Animals; D001343:Autophagy / Q000502:physiology*; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy*; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods*; D059630:Mesenchymal Stem Cells / Q000378:metabolism; D014470:Umbilical Cord / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D014945:Wound Healing / Q000502:physiology*