title: Potential extra-ribosomal functions of ribosomal proteins in Saccharomyces cerevisiae.
abstract: Ribosomal proteins (RPs), are essential components of the ribosomes, the molecular machines that turn mRNA blueprints into proteins, as they serve to stabilize the structure of the rRNA, thus improving protein biosynthesis. In addition, growing evidence suggests that RPs can function in other cellular roles. In the present review, we summarize several potential extra-ribosomal functions of RPs in ribosomal biogenesis, transcription activity, translation process, DNA repair, replicative life span, adhesive growth, and morphological transformation in Saccharomyces cerevisiae. However, the future in-depth studies are needed to identify these novel secondary functions of RPs in S. cerevisiae.
authors.affiliation: Key Laboratory of the Plateau of the Environmental Damage Control, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Lu
authors.affiliation: Key Laboratory of the Plateau of the Environmental Damage Control, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, China.
authors.forename: Yi-Fei
authors.initials: YF
authors.lastname: Zhu
authors.affiliation: Key Laboratory of the Plateau of the Environmental Damage Control, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Xiong
authors.affiliation: Key Laboratory of the Plateau of the Environmental Damage Control, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, China. Electronic address: wangrong-69@163.com.
authors.forename: Rong
authors.initials: R
authors.lastname: Wang
authors.affiliation: Key Laboratory of the Plateau of the Environmental Damage Control, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, China. Electronic address: jiazhengpinglzzyy@163.com.
authors.forename: Zhengping
authors.initials: Z
authors.lastname: Jia
mesh_terms: D002448:Cell Adhesion; D004260:DNA Repair; D053858:Metabolic Networks and Pathways; D014176:Protein Biosynthesis; D012269:Ribosomal Proteins / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000254:growth & development / Q000378:metabolism* / Q000502:physiology; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D012269:Ribosomal Proteins; D029701:Saccharomyces cerevisiae Proteins
keywords: Extra-ribosomal function; Ribosomal protein; Saccharomyces cerevisiae