title: Antibiotic Dosing in Critically Ill Patients Undergoing Renal Replacement Therapy.
abstract: Continuous renal replacement therapy is frequently used to manage acute renal failure in critically ill patients. Antibiotic drugs used to treat infections in critically ill patients need to be dosed on the basis of the method of renal replacement therapy to be used, degree of residual renal function, and the sensitivity of the organism to be treated. Antibiotic dosing regimens must then be continuously monitored and adjusted according to modifications made to the renal replacement circuit and the patient's underlying condition.
authors.affiliation: Gregory M. Susla is President, Washington DC Area Critical Care Society, 5301 Hines Rd, Frederick, MD 21704 (gsusla@att.net).
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Susla
mesh_terms: D058186:Acute Kidney Injury / Q000628:therapy*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D016638:Critical Illness / Q000534:rehabilitation*; D005260:Female; D006801:Humans; D017053:Infection Control / Q000379:methods*; D007239:Infections / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D017582:Renal Replacement Therapy / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents