title: Trapping of carbolithiation-derived tertiary benzylic α-lithio piperidines with carbon electrophiles: Controlling the formation of α-amino quaternary and vicinal stereocenters.
abstract: The interception of carbolithiation-derived tertiary benzylic α-lithio piperidines with carbon electrophiles, under HMPA-mediated conditions, has led to the diastereoselective synthesis of vicinally functionalized piperidines bearing α-amino quaternary stereocenters.
authors.affiliation: Department of Chemistry, Susquehanna University, 514 University Avenue, Selinsgrove, PA 17870, USA. beng@susqu.edu.
authors.forename: Timothy K
authors.initials: TK
authors.lastname: Beng
authors.forename: Nathan
authors.initials: N
authors.lastname: Fox
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Bassler
authors.forename: Amir
authors.initials: A
authors.lastname: Alwali
authors.forename: Kayla
authors.initials: K
authors.lastname: Sincavage
authors.forename: Ann Wens V
authors.initials: AW
authors.lastname: Silaire