title: Preparation of yolk-shell structured copper oxide@silica oxide spheres and their application in high performance electrochemical sensing of Formoterol fumarate residues in swine feed and tissues.
abstract: In this paper, we report a facile route to synthesize yolk-shell structured copper oxide@silica oxide (CuO@SiO2) spheres and their application to construct an electrochemical Formoterol fumarate (FF) sensor. The CuO@SiO2 was characterized by means of Fourier transform infrared spectroscopy, X-ray powder diffraction, Raman spectroscopy, scanning electron microscopy, and transmission electron microscopy. Further, FF was electrocatalytically oxidized at the CuO@SiO2 film modified glassy carbon electrode (GCE), which led to a sensitive determination of FF. The oxidation current of FF was linear with concentration in the range of 0.030-10 μM and the detection limit was found to be 5.0 nM (S/N = 3). The observed analytical parameters such as wide linear range, low detection limit and short response time were superior to previously reported FF sensors. Finally, it was demonstrated that the proposed sensor could be used for the selective determination of FF present in swine feed and tissues.
authors.affiliation: College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China. Electronic address: gantianxynu@163.com.
authors.forename: Tian
authors.initials: T
authors.lastname: Gan
authors.affiliation: College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China.
authors.forename: Zhaoxia
authors.initials: Z
authors.lastname: Shi
authors.affiliation: College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China.
authors.forename: Danyang
authors.initials: D
authors.lastname: Hu
authors.affiliation: College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Lv
authors.affiliation: College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China.
authors.forename: Junyong
authors.initials: J
authors.lastname: Sun
authors.affiliation: College of Chemistry and Chemical Engineering, Xinyang Normal University, Xinyang 464000, China.
authors.forename: Yanming
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000818:Animals; D003300:Copper / Q000737:chemistry*; D000068759:Formoterol Fumarate / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission / Q000379:methods*; D012822:Silicon Dioxide / Q000737:chemistry*; D013552:Swine
chemical_list: D012822:Silicon Dioxide; D003300:Copper; C000520:cuprous oxide; D000068759:Formoterol Fumarate
keywords: Cimaterol (PubChem CID: 2755); Clorprenaline (PubChem CID: 2810); CuO; Cupric oxide (PubChem CID: 14829); Electrochemical sensor; Formoterol fumarate; Formoterol fumarate (PubChem CID: 45358055); Potassium ferricyanide (PubChem CID: 26250); Salbutamol (PubChem CID: 2083); SiO(2); Silicon dioxide (PubChem CID: 24261); Terbutaline (PubChem CID: 5403); β-Adrenergic agonists