title: Oxidation of N,N-Disubstituted Hydroxylamines to Nitrones with Hypervalent Iodine Reagents.
abstract: Hypervalent iodine compounds are viable reagents for the oxidation of N,N-disubstituted hydroxylamines to the corresponding nitrones, with IBX performing best. The procedure is very simple and user-friendly and affords the target compounds with high efficiency and regioselectivity, highlighting IBX as the reagent of choice for preparation of aldonitrones from nonsymmetric hydroxylamines. Evidence for a mechanism involving nitrogen to iodine coordination has been collected.
authors.affiliation: †Dipartimento di Chimica "Ugo Schiff", Polo Scientifico e Tecnologico, Università di Firenze, Via della Lastruccia 13, 50019 Sesto Fiorentino (FI), Italy.
authors.forename: Camilla
authors.initials: C
authors.lastname: Matassini
authors.affiliation: †Dipartimento di Chimica "Ugo Schiff", Polo Scientifico e Tecnologico, Università di Firenze, Via della Lastruccia 13, 50019 Sesto Fiorentino (FI), Italy.|‡CNR-INO and LENS, via N. Carrara 1, 50019 Sesto Fiorentino (FI), Italy.
authors.forename: Camilla
authors.initials: C
authors.lastname: Parmeggiani
authors.affiliation: †Dipartimento di Chimica "Ugo Schiff", Polo Scientifico e Tecnologico, Università di Firenze, Via della Lastruccia 13, 50019 Sesto Fiorentino (FI), Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Cardona
authors.affiliation: †Dipartimento di Chimica "Ugo Schiff", Polo Scientifico e Tecnologico, Università di Firenze, Via della Lastruccia 13, 50019 Sesto Fiorentino (FI), Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Goti