title: Engineering polypeptide folding through trans double bonds: transformation of miniature β-meanders to hybrid helices.
abstract: Utilization of conjugated double bonds to engineer the novel folded miniature β-meander type structures, single step transformation of miniature β-meanders into ααγ(4)-hybrid peptide 10/12-helices using catalytic hydrogenation, their solution and single crystal conformations are reported.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pune-411 008, India. hn.gopi@iiserpune.ac.in.
authors.forename: Mothukuri
authors.initials: M
authors.lastname: Ganesh Kumar
authors.forename: Sushil N
authors.initials: SN
authors.lastname: Benke
authors.forename: K Muruga
authors.initials: KM
authors.lastname: Poopathi Raja
authors.forename: Hosahudya N
authors.initials: HN
authors.lastname: Gopi
mesh_terms: D000595:Amino Acid Sequence; D002384:Catalysis; D018360:Crystallography, X-Ray; D006865:Hydrogenation; D007536:Isomerism; D010455:Peptides / Q000737:chemistry*; D017510:Protein Folding; D017433:Protein Structure, Secondary
chemical_list: D010455:Peptides