title: Volumetric analysis of central body fat accurately predicts incidence of diabetes and hypertension in adults.
abstract: BACKGROUND
  Central adipose tissue is appreciated as a risk factor for cardiometabolic disorders. The purpose of this study was to determine the efficacy of a volumetric 3D analysis of central adipose tissue in predicting disease. Full body computerized tomography (CT) scans were obtained from 1225 female (518) and male (707) subjects, aged 18-88. Percent central body fat (%cBF) was determined by quantifying the adipose tissue volume from the dome of the liver to the pubic symphysis. Calcium score was determined from the calcium content of coronary arteries. Relationships between %cBF, BMI, and several cardiometabolic disorders were assessed controlling for age, sex, and race.
  
  
  RESULTS
  Higher %cBF was significantly greater for those with type 2 diabetes and hypertension, but not stroke or hypercholesterolemia. Simple anthropometric determination of BMI equally correlated with diabetes and hypertension as central body fat. Calcium scoring significantly correlated with all measurements of cardiovascular health, including hypertension, hypercholesterolemia, and heart disease.
  
  
  CONCLUSIONS
  Central body fat and BMI equally and highly predict incidence of hypertension and type 2 diabetes.
authors.affiliation: Departments of Physiology and Developmental Biology, Provo, UT USA.
authors.forename: Jacob T
authors.initials: JT
authors.lastname: Gibby
authors.affiliation: Novarad, American Fork, UT 84003 USA.
authors.forename: Dennis K
authors.initials: DK
authors.lastname: Njeru
authors.affiliation: Novarad, American Fork, UT 84003 USA.
authors.forename: Steven T
authors.initials: ST
authors.lastname: Cvetko
authors.affiliation: Health Science, Brigham Young University, Provo, UT USA.
authors.forename: Ray M
authors.initials: RM
authors.lastname: Merrill
authors.affiliation: Departments of Physiology and Developmental Biology, Provo, UT USA.
authors.forename: Benjamin T
authors.initials: BT
authors.lastname: Bikman
authors.affiliation: Accuscan Health Imaging Center, Salt Lake City, UT 84101 USA ; Novarad, American Fork, UT 84003 USA.
authors.forename: Wendell A
authors.initials: WA
authors.lastname: Gibby
keywords: CT Scan; Diabetes; Hypertension; Obesity; Volumetric Analysis