title: Effect of cleft lip palate repair on craniofacial growth.
abstract: OBJECTIVE
  The aim of this cross-sectional study was to compare craniofacial growth among operated and unoperated unilateral cleft lip and palate non-syndromic subjects.
  
  
  METHODS
  A sample of 180 subjects of Indian origin was selected. Of them, 90 were operated, and 90 were unoperated complete unilateral cleft lip and palate individuals. The subjects were divided into three age groups of 3-5, 8-10, and 20-25 years comprised of 30 patients in each group. The following measurements were evaluated: Angle and length of the cranial base; maxillary spatial positioning and length; mandibular spatial positioning; morphology and length; maxillomandibular relationship. Comparative analysis of the means between the groups was performed with Student's t-test at the significance levels of 5%. The ANOVA test has been performed to test the effect of time.
  
  
  RESULTS
  No significant differences were observed between the measurements that represented the angle and length of the cranial base of unoperated and the operated patients (P>0.05). There was statistically significant decrease (P˂0.05) in the maxillary length (Co-A; 69.00 mm in 3-5 years, 68.33 mm in 8-10 years, and 67.17 mm in 20-25 years age group), and SNA angle (74.83° in 3-5 years, 74.17 ° in 8-10 years and 73.17 ° in 20-25 years age group) in operated group. No significant difference noticed on cephalometric values of the mandible, except Ar-Go-Me angle (P˂0.05), which showed vertical growth pattern in unoperated patients (132.50 ° in 3-5 years, 132.00 ° I 8-10 years and 138.33 ° in 20-25 years age group).
  
  
  CONCLUSIONS
  Lip and palate repair has a significant influence on the maxilla and resulting in retarded growth of maxilla, which causes midface deficiency beyond acceptable sagittal limits. The Gonial angle showed vertical growth pattern in unoperated patients, but the cranial base angle and length of unoperated and the operated patients were similar.
authors.affiliation: Department of Preventive Dental Sciences-Orthodontics, College of Dentistry, Majmaah University, Zulfi, Kingdom of Saudi Arabia.
authors.forename: Zuber Ahamed
authors.initials: ZA
authors.lastname: Naqvi
authors.affiliation: Department of Orthodontics and Dentofacial Orthopaedics, JSS Dental College and Hospital, Mysore, Karnataka, India.
authors.forename: B M
authors.initials: BM
authors.lastname: Shivalinga
authors.affiliation: Department of Orthodontics and Dentofacial Orthopaedics, JSS Dental College and Hospital, Mysore, Karnataka, India.
authors.forename: S
authors.initials: S
authors.lastname: Ravi
authors.affiliation: Private Practice of General Dentistry, Jaipur, Rajasthan, India.
authors.forename: Syeda Sarah
authors.initials: SS
authors.lastname: Munawwar
keywords: Cephalometry; craniofacial growth; maxillomandibular; unilateral cleft lip and palate