title: Adolescent Scalp Psoriasis: Update on Topical Combination Therapy.
abstract: Plaque psoriasis can begin early in life and negatively affect quality of life. Topical agents are generally recommended as first-line therapy for plaque psoriasis. The synergy of a vitamin D analog and a steroid in a topical fixed-combination formulation provides more favorable effectiveness and tolerability as compared with either agent alone. The safety and effectiveness of a once-daily calcipotriene/betamethasone dipropionate topical suspension have been established in children 12 to 17 years of age with scalp plaque psoriasis. Combination topical formulations and once-daily dosing decrease regimen complexity and may increase adherence. Accommodation of vehicle preference may also improve adherence and real-life effectiveness.
authors.affiliation: Division of Pediatric and Adolescent Dermatology, University of California, San Diego, California; Rady Children's Hospital, San Diego, California;
authors.forename: Emily
authors.initials: E
authors.lastname: Osier
authors.affiliation: p -value communications, Cedar Knolls, New Jersey.
authors.forename: Barbara
authors.initials: B
authors.lastname: Gomez
authors.affiliation: Division of Pediatric and Adolescent Dermatology, University of California, San Diego, California; Rady Children's Hospital, San Diego, California;
authors.forename: Lawrence F
authors.initials: LF
authors.lastname: Eichenfield