title: Imaging Tumor Acidity: pH-Low Insertion Peptide Probe for Optoacoustic Tomography.
abstract: Optoacoustic tomography has been used for the detection of pancreatic ductal adenocarcinoma targeted by pH-low insertion peptide (pHLIP) conjugated to near-infrared fluorescent dye. It was proved that tumor targeting is pH dependent. The approach could have major implication for detection and monitoring of pancreatic and other cancers.
authors.affiliation: Division Biological and Medical Physics, Physics Department, University of Rhode Island, Kingston, Rhode Island. reshetnyak@uri.edu.
authors.forename: Yana K
authors.initials: YK
authors.lastname: Reshetnyak
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000378:metabolism*; D000818:Animals; D005260:Female; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000378:metabolism*
chemical_list: D008565:Membrane Proteins