title: [A Patient Who Underwent Surgery after CR to Chemotherapy for Scirrhous Gastric Cancer Suspected because of Lymphangitis Carcinomatosa].
abstract: A 58-year-old woman was diagnosed with scirrhous gastric cancer suspected because of lymphangitis carcinomatosa. She was treated with 10 courses of S-1+CDDP chemotherapy. After 3 years and 6 months, CR was obtained and she underwent curative total gastrectomy with D2 lymph node dissection plus resection of the spleen and transverse colon. The pathological results of the resected specimen were tub2>por, pT1a, N1 (No.7), M0, CY0, P0, and HER2 (3+). After surgical treatment, supraclavicular lymph node metastasis occurred, and the patient underwent trastuzumab+capecitabine therapy, which resulted in CR for 1 year and 6 months. Thus, for unresectable scirrhous gastric cancer, multidisciplinary therapy such as longterm chemotherapy including trastuzumab and surgery is useful.
authors.affiliation: Dept. of Surgery, Kinki University Faculty of Medicine.
authors.forename: Kohei
authors.initials: K
authors.lastname: Nishiki
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Sogabe
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Iwama
authors.forename: Tomoki
authors.initials: T
authors.lastname: Makino
authors.forename: Osamu
authors.initials: O
authors.lastname: Shiraishi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Yasuda
authors.forename: Masayuki
authors.initials: M
authors.lastname: Shinkai
authors.forename: Motohiro
authors.initials: M
authors.lastname: Imano
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Imamoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furukawa
authors.forename: Takushi
authors.initials: T
authors.lastname: Yasuda
mesh_terms: D002293:Adenocarcinoma, Scirrhous / Q000188:drug therapy* / Q000601:surgery; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008205:Lymphangitis / Q000209:etiology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D012008:Recurrence; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents