title: Epidemiological characteristics of a new focus of cutaneous leishmaniasis caused by Leishmania tropica in Settat, Morocco.
abstract: A new emerging focus of human cutaneous leishmaniasis (HCL) caused by Leishmania tropica was identified within the province of Settat. This study was performed in order to analyze the reasons of the extension of CL in this area, and to describe the clinico-epidemiological characteristic of this emerging focus during 2007-2012. A total of 553 suspected cases of CL were diagnosed in laboratory of Settat, controlled and confirmed in reference national laboratory of leishmaniasis in Rabat. Leishmania parasite is found in 356 cases. Most of them (33.89%) were recorded in localities of Ouled Ghalem (110 cases) and Laamarcha (102 cases) of El Borouj sector. The lesions were typically small, dry and mostly located on the face and extremities. Majority of infection (25%) was recorded among children under 11 years old, and female (72%). Strains of L. tropica were identified by PCR ITS1 from positive slides and zymodeme MON-102 was typed using isoenzyme technique on starch gel electrophoresis.
authors.affiliation: National Reference Laboratory of Leishmaniasis, National Institute of Hygiene, Rabat, Morocco. Electronic address: Fatima.inhr@gmail.com.
authors.forename: Amarir
authors.initials: A
authors.lastname: Fatima
authors.affiliation: National Reference Laboratory of Leishmaniasis, National Institute of Hygiene, Rabat, Morocco.
authors.forename: Sebti
authors.initials: S
authors.lastname: Faiza
authors.affiliation: National Reference Laboratory of Leishmaniasis, National Institute of Hygiene, Rabat, Morocco.
authors.forename: Fellah
authors.initials: F
authors.lastname: Hajiba
authors.affiliation: Université Montpellier 1 (UFR Médecine), Centre National de référence des leishmanioses, UMR "MIVEGEC" (CNRS 5290, IRD 224, UM1, UM2), Département de Parasitologie-Mycologie (Professeur Patrick Bastien), CHRU de Montpellier, 39, Avenue Charles Flahault, 34295 Montpellier Cedex 5, France.
authors.forename: Pratlong
authors.initials: P
authors.lastname: Francine
authors.affiliation: Université Montpellier 1 (UFR Médecine), Centre National de référence des leishmanioses, UMR "MIVEGEC" (CNRS 5290, IRD 224, UM1, UM2), Département de Parasitologie-Mycologie (Professeur Patrick Bastien), CHRU de Montpellier, 39, Avenue Charles Flahault, 34295 Montpellier Cedex 5, France.
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Dedet
authors.affiliation: National Reference Laboratory of Leishmaniasis, National Institute of Hygiene, Rabat, Morocco.
authors.forename: El Mansouri
authors.initials: el M
authors.lastname: Bouchra
authors.affiliation: FST, University of Sidi Med Ben Abdellah, Fés, Morocco.
authors.forename: Hmamouch
authors.initials: H
authors.lastname: Asmae
authors.affiliation: National Reference Laboratory of Leishmaniasis, National Institute of Hygiene, Rabat, Morocco.
authors.forename: Delouane
authors.initials: D
authors.lastname: Bouchra
authors.affiliation: FST, University of sultan Moulay Slimane, Beni Mellal, Morocco.
authors.forename: Habbari
authors.initials: H
authors.lastname: Khalid
authors.affiliation: Faculty of Science, Rabat Agdal, Morocco.
authors.forename: Sadak
authors.initials: S
authors.lastname: Abderrahim
authors.affiliation: Department of Parasitology, University El Quds, Palestine.
authors.forename: Abassi
authors.initials: A
authors.lastname: Ibrahim
authors.affiliation: National Reference Laboratory of Leishmaniasis, National Institute of Hygiene, Rabat, Morocco.
authors.forename: Rhajaoui
authors.initials: R
authors.lastname: Mohamed
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005843:Geography; D006801:Humans; D007223:Infant; D007895:Leishmania tropica / Q000235:genetics / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000453:epidemiology* / Q000469:parasitology; D008297:Male; D008875:Middle Aged; D009018:Morocco / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D055815:Young Adult
keywords: Cutaneous leishmaniasis; Leishmania tropica MON 102; Morocco; Settat