title: Necrotizing pulmonary aspergillosis and ventricular assist device infection: case report and review of literature.
abstract: Necrotizing pulmonary aspergillosis and Aspergillus device infection are rare and have potentially fatal complications after left ventricular assist device (LVAD) implantation. To date, few cases of patients surviving Aspergillus device infection have been published, with survival reported only after device removal. We present a patient implanted with an LVAD in whom necrotizing pulmonary aspergillosis with device involvement was successfully treated by segmentectomy and prolonged antifungal treatment without device exchange or removal. Similar cases in the literature were searched for and are discussed in view of the severity of this complication.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
authors.forename: A
authors.identifier: http://orcid.org/0000-0002-8420-171X
authors.initials: A
authors.lastname: Kornberger
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Walter
authors.affiliation: Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Jaeger
authors.affiliation: Department of Radiology, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Lehnert
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Soriano
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Moritz
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
authors.forename: U A
authors.initials: UA
authors.lastname: Stock
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Beiras-Fernandez
mesh_terms: D000328:Adult; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008297:Male; D016459:Prosthesis-Related Infections / Q000175:diagnosis*; D055732:Pulmonary Aspergillosis / Q000175:diagnosis*
keywords: Aspergillus; VAD; fungal infection; heart failure