title: Feeding Solanum glaucophyllum to preparturient multiparous cows prevents postparturient hypocalcemia.
abstract: Solanum glaucophyllum (SG) contains 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) glycosides. We investigated the effect of SG on hypocalcemia in cows. Serum levels of 1,25-(OH)2D3, total calcium and phosphorus dose-relatedly increased after feeding with SG, while serum magnesium and chloride levels fell (P < 0.05). We also performed an ethylenediaminetetraacetic acid (EDTA) infusion to induce artificial hypocalcemia. Cows that had been fed 4.0 mg/kg body weight of SG daily for 2 weeks had a higher serum concentration of total calcium at the end of EDTA infusion than those not fed SG (P < 0.05). In a field trial, multiparous cows were assigned to one of four groups: (1) no SG, (2) 1.3 g or (3) 2.6 g of SG daily from 14 days before the estimated calving day until 3 days after calving, or (4) a single feed of 35.75 g SG at 3 days before the estimated calving day. The concentrations of serum total calcium after the calving in each treatment group were (1) 7.4, (2) 7.9, (3) 8.0 and (4) 8.9 mg/dL and higher for (4) than for (1) (P < 0.05). The data suggests that feeding a high dose of SG before the calving may maintain higher concentrations of serum calcium after the calving.
authors.affiliation: Reseach and Development Center of Feed & Livestock Development Division, Nippon Formula Feed Manufacturing Company Limited, Tochigi, Japan.|Department of Animal Production Science United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.|University Farm, Department of Agriculture, Utsunomiya University, Tochigi, Japan.
authors.forename: Junichiro
authors.initials: J
authors.lastname: Ishii
authors.affiliation: Reseach and Development Center of Feed & Livestock Development Division, Nippon Formula Feed Manufacturing Company Limited, Tochigi, Japan.
authors.forename: Akifumi
authors.initials: A
authors.lastname: Uramoto
authors.affiliation: Department of Animal Production Science United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.|University Farm, Department of Agriculture, Utsunomiya University, Tochigi, Japan.
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Nagao
authors.affiliation: Reseach and Development Center of Feed & Livestock Development Division, Nippon Formula Feed Manufacturing Company Limited, Tochigi, Japan.
authors.forename: Hisaya
authors.initials: H
authors.lastname: Goto
mesh_terms: D000821:Animal Feed; D000818:Animals; D002117:Calcitriol / Q000032:analysis / Q000097:blood; D002118:Calcium / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000517:prevention & control*; D005260:Female; D006027:Glycosides / Q000032:analysis; D006996:Hypocalcemia / Q000097:blood / Q000517:prevention & control* / Q000662:veterinary*; D010298:Parity; D010758:Phosphorus / Q000097:blood; D049590:Postpartum Period; D011247:Pregnancy; D036061:Solanum glaucophyllum / Q000737:chemistry
chemical_list: D006027:Glycosides; D010758:Phosphorus; D002117:Calcitriol; D002118:Calcium
keywords: 1; 25dihydroxyvitaminD3; Holstein cows; Solanum glaucophyllum; calcium; milk fever