title: Diastereoselective synthesis of substituted diaziridines from simple ketones and aldehydes.
abstract: Diastereopure substituted diaziridines from simple ketones, aldehydes and amines are here reported. These important chemical scaffolds are obtained in the presence of a weak inorganic base and hydroxylamine O-sulfonic acid (HOSA). This method introduces three stereocenters in one step to provide a wide variety of substituted diaziridines with high yields and diastereoselectivities.
authors.affiliation: Department of Chemistry and Biochemistry, Rowan University, 201 Mullica Hill Rd, Glassboro, New Jersey, USA. moura-letts@rowan.edu.
authors.forename: Alexander W
authors.initials: AW
authors.lastname: Beebe
authors.forename: Emma F
authors.initials: EF
authors.lastname: Dohmeier
authors.forename: Gustavo
authors.initials: G
authors.lastname: Moura-Letts