title: Platelet-rich fibrin application in dentistry: a literature review.
abstract: The development of bioactive surgical additives to regulate the inflammation and increase the speed of healing process is one of the great challenges in clinical research. In this sense, platelet rich fibrin (PRF) appears as a natural and satisfactory alternative with favorable results and low risks. The following review attempts to summarize the relevant literature regarding the technique of using PRF, focusing on its preparation, advantages, and disadvantages of using it in clinical applications. PRF alone or in combination with other biomaterials seems to have several advantages and indications both for medicine and dentistry, due it is a minimally invasive technique with low risks and satisfactory clinical results.
authors.affiliation: Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera Temuco, Chile ; Dental Materials and Prosthodontics Department, Ribeirão Preto Dental School, University of São Paulo Ribeirão Preto, SP, Brazil.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Borie
authors.affiliation: Private practice Temuco, Chile.
authors.forename: Daniel García
authors.initials: DG
authors.lastname: Oliví
authors.affiliation: Dental Materials and Prosthodontics Department, Ribeirão Preto Dental School, University of São Paulo Ribeirão Preto, SP, Brazil.
authors.forename: Iara Augusta
authors.initials: IA
authors.lastname: Orsi
authors.affiliation: Private practice Pinhal Grande, RS, Brazil.
authors.forename: Katia
authors.initials: K
authors.lastname: Garlet
authors.affiliation: Dental School, Universidad de La Frontera Temuco, Chile.
authors.forename: Benjamín
authors.initials: B
authors.lastname: Weber
authors.affiliation: Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera Temuco, Chile.
authors.forename: Víctor
authors.initials: V
authors.lastname: Beltrán
authors.affiliation: Research Centre in Dental Sciences (CICO), Dental School, Universidad de La Frontera Temuco, Chile.
authors.forename: Ramón
authors.initials: R
authors.lastname: Fuentes
keywords: Blood platelet; bone regeneration; fibrin; oral surgery; platelet-rich fibrin