title: Perspectives and Pitfalls in Nucleic Acids Crystallography.
abstract: X-ray crystallography offers precious and striking knowledge on biomolecular architectures. Although safeguards do exist to guarantee the accuracy of the structures deposited in databases, they are not always applied, leading to the spread of inaccurate data. The importance of validation reports in the publication process is emphasized.
authors.affiliation: Architecture et Réactivité de l'ARN, Institut de Biologie Moléculaire et Cellulaire, UPR 9002 CNRS/Université de Strasbourg, 15 Rue René Descartes, Strasbourg, 67084, France, e.westhof@unistra.fr.
authors.forename: Eric
authors.initials: E
authors.lastname: Westhof
mesh_terms: D018360:Crystallography, X-Ray / Q000379:methods*; D004247:DNA / Q000737:chemistry; D008967:Molecular Biology / Q000379:methods; D009696:Nucleic Acids / Q000737:chemistry*; D011487:Protein Conformation; D012313:RNA / Q000737:chemistry
chemical_list: D009696:Nucleic Acids; D012313:RNA; D004247:DNA