title: MB4-2 breakpoint in MMSET combined with del(17p) defines a subset of t(4;14) multiple myeloma with very poor prognosis.
authors.affiliation: Immuno-Hematology, Saint-Louis Hospital, Paris, France Université Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM UMR 1126 Institut Universitaire d'Hématologie, Paris, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Lazareth
authors.affiliation: Université Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM UMR 1126 Institut Universitaire d'Hématologie, Paris, France.
authors.forename: Xiu-Yi
authors.initials: XY
authors.lastname: Song
authors.affiliation: Biological Hematology, Saint-Louis Hospital, Paris, France.
authors.forename: Aurelie
authors.initials: A
authors.lastname: Coquin
authors.affiliation: Hematology, Avicenne Hospital, Bobigny, France.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Harel
authors.affiliation: Hematology, Avicenne Hospital, Bobigny, France.
authors.forename: Lionel
authors.initials: L
authors.lastname: Karlin
authors.affiliation: Hematology, Henri Mondor Hospital, Creteil, France.
authors.forename: Karim
authors.initials: K
authors.lastname: Belhadj
authors.affiliation: Hematology, Pitie Salpetriere Hospital, Paris, France.
authors.forename: Damien
authors.initials: D
authors.lastname: Roos-Weil
authors.affiliation: Hematology, Necker Hospital, Paris, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Frenzel
authors.affiliation: Hematology, Cochin Hospital, Paris, France.
authors.forename: Jerôme
authors.initials: J
authors.lastname: Tamburini
authors.affiliation: Hematology, Caen Hospital, Paris, France.
authors.forename: Margaret
authors.initials: M
authors.lastname: Macro
authors.affiliation: Biostatistics, Saint-Louis Hospital, Paris, France.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Chevret
authors.affiliation: Biological Hematology, Purpan Hospital, Toulouse, France.
authors.forename: Hervé Avet
authors.initials: HA
authors.lastname: Loiseau
authors.affiliation: University Hospital, Nantes, France.
authors.forename: Stephane
authors.initials: S
authors.lastname: Minvielle
authors.affiliation: Immuno-Hematology, Saint-Louis Hospital, Paris, France Université Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM UMR 1126 Institut Universitaire d'Hématologie, Paris, France.
authors.forename: Jean Paul
authors.initials: JP
authors.lastname: Fermand
authors.affiliation: Biological Hematology, Saint-Louis Hospital, Paris, France.
authors.forename: Jean
authors.initials: J
authors.lastname: Soulier
authors.affiliation: Université Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM UMR 1126 Institut Universitaire d'Hématologie, Paris, France.
authors.forename: Jean Christophe
authors.initials: JC
authors.lastname: Bories
authors.affiliation: Immuno-Hematology, Saint-Louis Hospital, Paris, France Université Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM UMR 1126 Institut Universitaire d'Hématologie, Paris, France bertrand.arnulf@sls.aphp.fr.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Arnulf
mesh_terms: D000328:Adult; D000368:Aged; D002883:Chromosomes, Human, Pair 14 / Q000235:genetics*; D002894:Chromosomes, Human, Pair 4 / Q000235:genetics*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000235:genetics* / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D015996:Survival Rate; D014178:Translocation, Genetic
keywords: MB4 breakpoint; MMSET; heterogeneity; prognostic factor; t(4/14) translocation