title: Simultaneous Electro-Optical Tracking for Nanoparticle Recognition and Counting.
abstract: We present the first detailed experimental observation and analysis of nanoparticle electrophoresis through a nanochannel obtained with synchronous high-bandwidth electrical and camera recordings. Optically determined particle diffusion coefficients agree with values extracted from fitting electrical transport measurements to distributions from 1D Fokker-Planck diffusion-drift theory. This combined tracking strategy enables optical recognition and electrical characterization of nanoparticles in solution, which can have a broad range of applications in biology and materials science.
authors.affiliation: Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Angeli
authors.affiliation: Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Volpe
authors.affiliation: Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Fanzio
authors.affiliation: Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Repetto
authors.affiliation: Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Firpo
authors.affiliation: Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Guida
authors.affiliation: Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Lo Savio
authors.affiliation: Department of Physics and Chemistry/Chemical Biology, Northeastern University , Boston 02115, Massachusetts, United States.
authors.forename: Meni
authors.initials: M
authors.lastname: Wanunu
authors.affiliation: Nanomed Laboratories, Dipartimento di Fisica, Università di Genova , 16146 Genova, Italy.
authors.forename: Ugo
authors.initials: U
authors.lastname: Valbusa
mesh_terms: D004058:Diffusion; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D004586:Electrophoresis / Q000295:instrumentation*; D004867:Equipment Design; D005456:Fluorescent Dyes / Q000032:analysis; D056656:Lab-On-A-Chip Devices; D053758:Nanoparticles / Q000032:analysis*; D036103:Nanotechnology / Q000295:instrumentation; D055095:Optics and Photonics / Q000295:instrumentation; D010316:Particle Size; D014741:Video Recording
chemical_list: D004129:Dimethylpolysiloxanes; D005456:Fluorescent Dyes; C013830:baysilon
keywords: Single particle tracking; nanoparticle diffusion; polymeric nanochannels; resistive pulse sensing; translocation dynamics