title: WEB-DL Endovascular Treatment of Wide-Neck Bifurcation Aneurysms: Long-Term Results in a European Series.
abstract: OBJECTIVE
  Flow disruption with the WEB-DL device has been used safely for the treatment of wide-neck bifurcation aneurysms. The stability of aneurysm occlusion after this treatment was evaluated in the short and midterm, but not in the long term. This retrospective multicenter European study is the continuation of an already published series dealing with short- and midterm anatomic results and analyzes long-term data in patients treated with the WEB-DL.
  
  
  METHODS
  Twelve European neurointerventional centers initially participated in the study. In addition to data collected for the initial publication, images obtained at long-term follow-up were collected and independently analyzed by the same experienced interventional neuroradiologist.
  
  
  RESULTS
  Of the initial 45 patients, 26 (20 women and 6 men; 35-73 years of age; mean, 55.2 ± 10.6 years; median, 55.5 years) with 26 aneurysms treated with the WEB-DL device had long-term follow-up (median, 27.4 months). Three of 26 patients (11.5%) were retreated between short- and midterm follow-up, and none, between mid- and long-term follow-up. Long-term aneurysm occlusion in the 19 patients treated with the WEB only and not retreated during follow-up was complete occlusion in 13/19 patients (68.4%), including aneurysms with opacification of the proximal recess in 9/19 patients (47.4%), neck remnant in 3/19 patients (15.8%), and aneurysm remnant in 3/19 patients (15.8%). In all patients (100.0%), aneurysm occlusion was stable between midterm and long-term follow-up.
  
  
  CONCLUSIONS
  The results suggest that WEB treatment of wide-neck bifurcation aneurysms offers long-term stable occlusion.
authors.affiliation: From the Department of Neuroradiology (L.P.), Hôpital Maison-Blanche, Université Reims-Champagne-Ardenne, Reims, France lpierot@gmail.com.
authors.forename: L
authors.initials: L
authors.lastname: Pierot
authors.affiliation: Department of Diagnostic and Interventional Radiology and Neuroradiology (J.K., V.S.), Helios General Hospital, Erfurt, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Klisch
authors.affiliation: Department of Neuroradiology (T.L.), Universitätsklinikum Köln, Cologne, Germany.
authors.forename: T
authors.identifier: http://orcid.org/0000-0001-5640-7780
authors.initials: T
authors.lastname: Liebig
authors.affiliation: Department of Neuroradiology (J.-Y.G.), CHU Rennes, Rennes, France.
authors.forename: J-Y
authors.initials: JY
authors.lastname: Gauvrit
authors.affiliation: Department of Neuroradiology (M.L.), Ospedale Bellaria, Bologna University, Bologna, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Leonardi
authors.affiliation: Department of Neuroradiology (N.P.N.), Ospedale Galliera, Genova, Italy.
authors.forename: N P
authors.initials: NP
authors.lastname: Nuzzi
authors.affiliation: Department of Neuroradiology (F.D.P.), Ospedale Santa Maria, Treviso, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Di Paola
authors.affiliation: Department of Diagnostic and Interventional Radiology and Neuroradiology (J.K., V.S.), Helios General Hospital, Erfurt, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Sychra
authors.affiliation: Department of Neuroradiology (B.M., B.L.), Erasme University Hospital, Brussels, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Mine
authors.affiliation: Department of Neuroradiology (B.M., B.L.), Erasme University Hospital, Brussels, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Lubicz
mesh_terms: D000328:Adult; D000368:Aged; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D005060:Europe; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome