title: [Treatment of a severe Clostridium difficile infection with colonic lavages. Report of one case].
abstract: A loop ileostomy with intraoperative anterograde colonic lavage has been described as an alternative to colectomy in the management of cases of Clostridium difficile infection refractory to medical treatment. We report a 69 years old diabetic women admitted with a septic shock. An abdominal CAT scan showed a pan-colitis that seemed to be infectious. A polymerase chain reaction was positive for Clostridium Difficile. Due to the failure to improve after full medical treatment, a derivative loop ileostomy and intra-operatory colonic lavage were performed, leaving a Foley catheter in the proximal colon. In the postoperative period, anterograde colonic instillations of Vancomycin flushes through the catheter were performed every 6 hours. Forty eight hours after surgery, the patient improved. A colonoscopy prior to discharge showed resolution of the pseudomembranous colitis.
authors.forename: Felipe
authors.initials: F
authors.lastname: Quezada
authors.forename: Richard
authors.initials: R
authors.lastname: Castillo
authors.forename: Constanza
authors.initials: C
authors.lastname: Villalón
authors.forename: José Miguel
authors.initials: JM
authors.lastname: Zúñiga
authors.forename: Carla
authors.initials: C
authors.lastname: Manterola
authors.forename: María Elena
authors.initials: ME
authors.lastname: Molina
authors.forename: Felipe
authors.initials: F
authors.lastname: Bellolio
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Urrejola
mesh_terms: D000368:Aged; D000818:Animals; D016360:Clostridioides difficile; D003131:Combined Modality Therapy / Q000379:methods; D004761:Enterocolitis, Pseudomembranous / Q000628:therapy*; D005260:Female; D006801:Humans; D007081:Ileostomy / Q000379:methods*; D007507:Therapeutic Irrigation / Q000379:methods*; D014640:Vancomycin / Q000008:administration & dosage
chemical_list: D014640:Vancomycin