title: Retinal Imaging of Infants on Spectral Domain Optical Coherence Tomography.
abstract: Spectral domain coherence tomography (SD OCT) has become an important tool in the management of pediatric retinal diseases. It is a noncontact imaging device that provides detailed assessment of the microanatomy and pathology of the infant retina with a short acquisition time allowing office examination without the requirement of anesthesia. Our understanding of the development and maturation of the infant fovea has been enhanced by SD OCT allowing an in vivo assessment that correlates with histopathology. This has helped us understand the critical correlation of foveal development with visual potential in the first year of life and beyond. In this review, we summarize the recent literature on the clinical applications of SD OCT in studying the pathoanatomy of the infant macula, its ability to detect subclinical features, and its correlation with disease and vision. Retinopathy of prematurity and macular edema have been discussed in detail. The review also summarizes the current status of SD OCT in other infant retinal conditions, imaging the optic nerve, the choroid, and the retinal nerve fibre in infants and children, and suggests future areas of research.
authors.affiliation: Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore, India.
authors.forename: Anand
authors.initials: A
authors.lastname: Vinekar
authors.affiliation: Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore, India ; Department of Ophthalmology, Duke University, Durham, NC, USA.
authors.forename: Shwetha
authors.initials: S
authors.lastname: Mangalesh
authors.affiliation: Narayana Nethralaya Postgraduate Institute of Ophthalmology, Bangalore, India.
authors.forename: Chaitra
authors.initials: C
authors.lastname: Jayadev
authors.affiliation: Department of Ophthalmology, Duke University, Durham, NC, USA.
authors.forename: Ramiro S
authors.initials: RS
authors.lastname: Maldonado
authors.affiliation: Department of Ophthalmology, Maastricht University, Netherlands.
authors.forename: Noel
authors.initials: N
authors.lastname: Bauer
authors.affiliation: Department of Ophthalmology, Duke University, Durham, NC, USA.
authors.forename: Cynthia A
authors.initials: CA
authors.lastname: Toth
mesh_terms: D002829:Choroid / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008269:Macular Edema / Q000175:diagnosis / Q000473:pathology*; D009900:Optic Nerve / Q000473:pathology; D012160:Retina / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*