title: Synthesis of deuterium-labeled hydroxybupropion.
abstract: This paper describes the synthesis of deuterium-labeled hydroxybupropion. Mass spectrometry analysis of the compound revealed over 98% deuterium enrichment.
authors.affiliation: School of Environmental Science, Nanjing Xiaozhuang University, 3601 Hongjing Road, Nanjing, Jiangsu, 211171, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.affiliation: College of Petroleum Engineering, Yangtze University, 1 Daxue Road, Caidian Zone, Wuhan, Hubei, 434023, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Tian
authors.affiliation: Hi-Tech Research Institute and State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, 5 Xinmofan Road, Nanjing, Jiangsu, 210009, China.
authors.forename: Chi
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Hi-Tech Research Institute and State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing University of Technology, 5 Xinmofan Road, Nanjing, Jiangsu, 210009, China.
authors.forename: Liqin
authors.initials: L
authors.lastname: Chen
mesh_terms: D018687:Antidepressive Agents, Second-Generation / Q000138:chemical synthesis*; D016642:Bupropion / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D003903:Deuterium / Q000737:chemistry*
chemical_list: D018687:Antidepressive Agents, Second-Generation; C580748:hydroxybupropion; D016642:Bupropion; D003903:Deuterium
keywords: bupropion; deuterium-labeled; hydroxybupropion; metabolite; synthesis