title: Oropharyngeal Carriage of Meningococcus in Portugal by Group and Clonal Complex 6 Years After Adolescent Vaccine Campaign.
abstract: Portugal introduced (2+1) conjugate Meningococcal group C vaccine in 2006 with high coverage catch up to 18 years and has given only 1 dose at 1 year since 2012. Among 601 student oropharyngeal swabs, meningococcal carriage rate was 13.3% (A-0%, B-5.3%, C-0.3%, W-0.2%, X-0.2% and Y-1.7%). C and W strains were of potentially disease-causing clonal complexes (cc) but not the hyperinvasive cc11.
authors.affiliation: From the *Infectious Diseases Unit and Emergency Service, Hospital Pediátrico de Coimbra, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; †Faculty of Medicine, Universidade de Coimbra, Coimbra, Portugal; ‡Schools of Clinical Sciences and Cellular and Molecular Medicine and §School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; and ¶Vaccine Evaluation Unit, Public Health England, North West, Manchester, United Kingdom.
authors.forename: Fernanda
authors.initials: F
authors.lastname: Rodrigues
authors.forename: Begonia
authors.initials: B
authors.lastname: Morales-Aza
authors.forename: Hannah
authors.initials: H
authors.lastname: Christensen
authors.forename: Jessica
authors.initials: J
authors.lastname: Giles
authors.forename: Muriel
authors.initials: M
authors.lastname: Ferreira
authors.forename: Paulina
authors.initials: P
authors.lastname: Sikora
authors.forename: Ines
authors.initials: I
authors.lastname: Madanelo
authors.forename: Jay
authors.initials: J
authors.lastname: Lucidarme
authors.forename: Luis
authors.initials: L
authors.lastname: Januário
authors.forename: Adam
authors.initials: A
authors.lastname: Finn
mesh_terms: D000293:Adolescent; D000328:Adult; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D032541:Mass Vaccination; D008589:Meningococcal Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000517:prevention & control; D022401:Meningococcal Vaccines / Q000276:immunology*; D009345:Neisseria meningitidis / Q000235:genetics; D009960:Oropharynx / Q000382:microbiology*; D011174:Portugal / Q000453:epidemiology; D055815:Young Adult
chemical_list: D022401:Meningococcal Vaccines