title: Complete genome sequence of Rhodococcus erythropolis BG43 (DSM 46869), a degrader of Pseudomonas aeruginosa quorum sensing signal molecules.
abstract: Rhodococcus erythropolis BG43 was isolated from soil and characterized as a degrader of the quorum sensing signal molecules 2-heptyl-3-hydroxy-4(1H)-quinolone (the Pseudomonas quinolone signal, PQS) and 2-heptyl-4(1H)-quinolone, produced by Pseudomonas aeruginosa. The complete genome of R. erythropolis BG43 consists of a circular chromosome and three plasmids, one of them circular and two linear ones. In total, 6158 protein-coding regions were identified. With this genome sequence, the genetic basis of its quorum-quenching ability and possible biotechnological applications can be explored further.
authors.affiliation: Technology Platform Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Sequenz 1, 33615 Bielefeld, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Rückert
authors.affiliation: Institute of Molecular Microbiology and Biotechnology, University of Münster, Corrensstraße 3, 48149 Münster, Germany.
authors.forename: Franziska S
authors.initials: FS
authors.lastname: Birmes
authors.affiliation: Institute of Molecular Microbiology and Biotechnology, University of Münster, Corrensstraße 3, 48149 Münster, Germany.
authors.forename: Christine
authors.initials: C
authors.lastname: Müller
authors.affiliation: Institute of Molecular Microbiology and Biotechnology, University of Münster, Corrensstraße 3, 48149 Münster, Germany.
authors.forename: Heiko
authors.initials: H
authors.lastname: Niewerth
authors.affiliation: Technology Platform Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Sequenz 1, 33615 Bielefeld, Germany.
authors.forename: Anika
authors.initials: A
authors.lastname: Winkler
authors.affiliation: Institute of Molecular Microbiology and Biotechnology, University of Münster, Corrensstraße 3, 48149 Münster, Germany. Electronic address: fetzner@uni-muenster.de.
authors.forename: Susanne
authors.initials: S
authors.lastname: Fetzner
authors.affiliation: Technology Platform Genomics, Center for Biotechnology (CeBiTec), Bielefeld University, Sequenz 1, 33615 Bielefeld, Germany. Electronic address: joern.kalinowski@cebitec.uni-bielefeld.de.
authors.forename: Jörn
authors.initials: J
authors.lastname: Kalinowski
mesh_terms: D001483:Base Sequence; D016680:Genome, Bacterial; D059014:High-Throughput Nucleotide Sequencing; D011550:Pseudomonas aeruginosa / Q000378:metabolism*; D053038:Quorum Sensing; D012240:Rhodococcus / Q000235:genetics*; D015398:Signal Transduction
keywords: Pseudomonas aeruginosa; quorum quenching