title: Predictive modeling and threshold scores for care seeking among women with urinary incontinence: The short forms of the Pelvic Floor Distress Inventory and Urogenital Distress Inventory.
abstract: To further the interpretability of the Pelvic Floor Distress Inventory (PFDI-20) and Urogenital Distress Inventory (UDI-6) by (i) evaluating the ability of these measures to distinguish between women with urinary incontinence who do and do not seek care, (ii) defining PFDI-20 and UDI-6 threshold scores above which women with urinary incontinence seek care, and (iii) developing a predictive model for incontinence care seeking.
  
  
  
  An observational study was conducted with two groups of women with urinary incontinence: 256 who had not sought care and 90 seeking initial care at a tertiary center. Sample sizes were based upon the prevalence of care seeking for urinary incontinence and the number of potential predictors for care seeking. Wilcoxon rank-sum tests, receiver operating characteristics, and multivariable logistic regression were use to achieve the study aims.
  
  
  
  Women with urinary incontinence who sought care had higher median PFDI-20 and UDI-6 scores compared to non-care seekers (73.96 vs. 16.67, P < 0.0001, and 41.67 vs. 8.33, P < 0.0001). A PFDI-20 score of 33.33 (83.33% sensitivity and 79.30% specificity) had very good discriminatory accuracy in distinguishing care and non-care seekers (AUC 0.886 ± 0.019 [95%CI 0.8518, 0.9254] P < 0.0001). A UDI-6 score of 25.00 (83.33% sensitivity and 83.59% specificity) had excellent discriminatory accuracy in distinguishing care and non-care seekers (AUC 0.9025 ± 0.0190 [95%CI 0.8653, 0.9398] P < 0.0001). A multivariable predictive model accurately identified 82.4% of care and non-care seekers.
  
  
  
  A PFDI-20 score of 33.33 and UDI-6 score of 25.00 provide meaningful benchmarks for care seeking among women with urinary incontinence. Neurourol. Urodynam. 35:949-954, 2016. © 2015 Wiley Periodicals, Inc.
authors.affiliation: Female Pelvic Medicine and Reconstructive Surgery, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, Chicago, Illinois. agafni-kane@northshore.org.
authors.forename: Adam
authors.initials: A
authors.lastname: Gafni-Kane
authors.affiliation: Center for Biomedical Research Informatics, NorthShore University HealthSystem, Chicago, Illinois.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Female Pelvic Medicine and Reconstructive Surgery, NorthShore University HealthSystem, University of Chicago Pritzker School of Medicine, Chicago, Illinois.
authors.forename: Sylvia M
authors.initials: SM
authors.lastname: Botros
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D052776:Female Urogenital Diseases / Q000523:psychology* / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D008962:Models, Theoretical; D010342:Patient Acceptance of Health Care / Q000523:psychology*; D059952:Pelvic Floor Disorders / Q000523:psychology* / Q000628:therapy*; D011237:Predictive Value of Tests; D011788:Quality of Life; D057566:Self Report; D011795:Surveys and Questionnaires; D014549:Urinary Incontinence / Q000523:psychology* / Q000628:therapy*
keywords: health care seeking behavior; lower urinary tract symptoms; quality of life; questionnaires; urinary incontinence