title: "Vanishing Bone Disease" in Maxillofacial Region: A Review and Our Experience.
abstract: Vanishing bone disease (VBD) is a rare disease of unknown etiology which is characterised by progressive replacement of bony framework by proliferation of endothelial lined lymphatic vessels. It has been given numerous names like massive osteolysis, Gorham's disease, phantom bone disease, and progressive osteolysis. It has no age, sex or race predilection. It may involve single or multiple bones and spread of the disease does not respect the relevant joint as boundary. The first report of the disease was published around two decades back but the mysterious nature of its etiology and ideal management strategy has still not been completely unfolded. The disease may functionally or aesthetically effect the patient and also has the potential to be life threatening. The first case of VBD in maxillofacial region was reported by Romer in 1924, Handbuch der speziellen pathologischen Anatomie and histology, Springer, Berlin. Since then, there have been few case reports of the same in maxillofacial region. We present a review of cases of VBD in maxillofacial region reported in literature along with our experience of a case.
authors.affiliation: Flt. Lt. Rajan Dhall Fortis Hospital, Vasant Kunj, New Delhi, India.
authors.forename: Ujjwal
authors.initials: U
authors.lastname: Gulati
authors.affiliation: Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences, New Delhi, India.
authors.forename: Sujata
authors.initials: S
authors.lastname: Mohanty
authors.affiliation: Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences, New Delhi, India.
authors.forename: Jitender
authors.initials: J
authors.lastname: Dabas
authors.affiliation: Pathology Consultancy Services, B-6, Sector 27, Noida, 201301 Uttar Pradesh India.
authors.forename: Nidhee
authors.initials: N
authors.lastname: Chandra
keywords: Bone resorption; Gorham’s disease; Haemangiomatosis; Lymphatic proliferation; Massive osteolysis