title: [Influence of non-diabetic hyperglycemia on postoperative complications following laparoscopic colorectal cancer resection].
abstract: OBJECTIVE
  To investigate the influence of non-diabetic hyperglycemia on postoperative complications following laparoscopic colorectal cancer resection.
  
  
  METHODS
  Clinical data of 636 patients undergoing laparoscopic colorectal cancer resection in The Affiliated Nanhai Hospital of Southern Medical University between 2009 and 2013 were analyzed retrospectively. After excluding cases with diabetes mellitus, the patients were divided into the hyperglycemia group (blood glucose level>7.8 mmol/L at any time during hospitalization period, n=161) and the non-hyperglycemia group (n=309).
  
  
  RESULTS
  Compared to non-hyperglycemia group, hyperglycemia group had more intraoperative blood loss [(186±80) ml vs. (158±74) ml, P=0.007] and longer postoperative hospital stay [(14.0±6.8) d vs. (11.2±5.5) d, P=0.013]. The overall rate of postoperative complication was 24.8% and 16.5% respectively (P=0.030), in the hyperglycemia and the non-hyperglycemia groups, and the mortality was 1.2% and 0.6% respectively (P=0.541). Multivariable analysis showed hyperglycemia was an independent risk factor of postoperative complication (RR=2.425, 95% CI:1.210-4.226, P=0.006).
  
  
  CONCLUSIONS
  Non-diabetic hyperglycemia may increase the risk of postoperative complications following laparoscopic colorectal cancer resection. Perioperative blood glucose monitoring should be performed, regardless of patients with or without diabetes.
authors.affiliation: Department of Endocriology, The Affiliated Nanhai Hospital of Southern Medical University, Guangdong Foshan 528200, China. zcpl93@163.corn.
authors.forename: Chunping
authors.initials: C
authors.lastname: Zeng
authors.forename: Youping
authors.initials: Y
authors.lastname: Chen
authors.forename: Qingshui
authors.initials: Q
authors.lastname: Yang
authors.forename: Xinfang
authors.initials: X
authors.lastname: Liao
mesh_terms: D015179:Colorectal Neoplasms; D003920:Diabetes Mellitus; D013505:Digestive System Surgical Procedures; D006801:Humans; D006943:Hyperglycemia; D010535:Laparoscopy; D011183:Postoperative Complications; D011184:Postoperative Period; D012189:Retrospective Studies; D012307:Risk Factors