title: Tea consumption and mortality of all cancers, CVD and all causes: a meta-analysis of eighteen prospective cohort studies.
abstract: Epidemiological studies have demonstrated inconsistent associations between tea consumption and mortality of all cancers, CVD and all causes. To obtain quantitative overall estimates, we conducted a dose-response meta-analysis of prospective cohort studies. A literature search in PubMed and Embase up to April 2015 was conducted for all relevant papers published. Random-effects models were used to calculate pooled relative risks (RR) with 95 % CI. In eighteen prospective studies, there were 12 221, 11 306 and 55 528 deaths from all cancers, CVD and all causes, respectively. For all cancer mortality, the summary RR for the highest v. lowest category of green tea and black tea consumption were 1·06 (95 % CI 0·98, 1·15) and 0·79 (95 % CI 0·65, 0·97), respectively. For CVD mortality, the summary RR for the highest v. lowest category of green tea and black tea consumption were 0·67 (95 % CI 0·46, 0·96) and 0·88 (95 % CI 0·77, 1·01), respectively. For all-cause mortality, the summary RR for the highest v. lowest category of green tea and black tea consumption were 0·80 (95 % CI 0·68, 0·93) and 0·90 (95 % CI 0·83, 0·98), respectively. The dose-response analysis indicated that one cup per d increment of green tea consumption was associated with 5 % lower risk of CVD mortality and with 4 % lower risk of all-cause mortality. Green tea consumption was significantly inversely associated with CVD and all-cause mortality, whereas black tea consumption was significantly inversely associated with all cancer and all-cause mortality.
authors.affiliation: 1Department of Food Science and Nutrition,Zhejiang University,Hangzhou 310058,People's Republic of China.
authors.forename: Jun
authors.initials: J
authors.lastname: Tang
authors.affiliation: 1Department of Food Science and Nutrition,Zhejiang University,Hangzhou 310058,People's Republic of China.
authors.forename: Ju-Sheng
authors.initials: JS
authors.lastname: Zheng
authors.affiliation: 2Second Provincial People's Hospital of Gansu,Lanzhou 730000,People's Republic of China.
authors.forename: Ling
authors.initials: L
authors.lastname: Fang
authors.affiliation: 2Second Provincial People's Hospital of Gansu,Lanzhou 730000,People's Republic of China.
authors.forename: Yongxin
authors.initials: Y
authors.lastname: Jin
authors.affiliation: 1Department of Food Science and Nutrition,Zhejiang University,Hangzhou 310058,People's Republic of China.
authors.forename: Wenwen
authors.initials: W
authors.lastname: Cai
authors.affiliation: 1Department of Food Science and Nutrition,Zhejiang University,Hangzhou 310058,People's Republic of China.
authors.forename: Duo
authors.initials: D
authors.lastname: Li
mesh_terms: D028241:Camellia sinensis; D002318:Cardiovascular Diseases / Q000401:mortality*; D002423:Cause of Death; D006801:Humans; D009369:Neoplasms / Q000401:mortality*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D013662:Tea
chemical_list: D010936:Plant Extracts; D013662:Tea
keywords: All-cause mortality; CVD; Cancers; Meta-analyses; Mortality; Tea