title: Structural basis of the Norrin-Frizzled 4 interaction.
authors.affiliation: Department of Biological Structure, University of Washington, Seattle, WA 98195, USA.|State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
authors.forename: Guobo
authors.initials: G
authors.lastname: Shen
authors.affiliation: Van Andel Research Institute, Grand Rapids, MI 49503, USA.
authors.forename: Jiyuan
authors.initials: J
authors.lastname: Ke
authors.affiliation: Department of Biological Structure, University of Washington, Seattle, WA 98195, USA.
authors.forename: Zhizhi
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Biological Structure, University of Washington, Seattle, WA 98195, USA.
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Cheng
authors.affiliation: Van Andel Research Institute, Grand Rapids, MI 49503, USA.
authors.forename: Xin
authors.initials: X
authors.lastname: Gu
authors.affiliation: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
authors.forename: Yuquan
authors.initials: Y
authors.lastname: Wei
authors.affiliation: Van Andel Research Institute, Grand Rapids, MI 49503, USA.
authors.forename: Karsten
authors.initials: K
authors.lastname: Melcher
authors.affiliation: Van Andel Research Institute, Grand Rapids, MI 49503, USA.|VARI-SIMM Center, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
authors.forename: H Eric
authors.initials: HE
authors.lastname: Xu
authors.affiliation: Department of Biological Structure, University of Washington, Seattle, WA 98195, USA.
authors.forename: Wenqing
authors.initials: W
authors.lastname: Xu
mesh_terms: D018360:Crystallography, X-Ray; D005136:Eye Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D051157:Frizzled Receptors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D016296:Mutagenesis; D009419:Nerve Tissue Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D054730:Protein Interaction Domains and Motifs; D017434:Protein Structure, Tertiary
chemical_list: D005136:Eye Proteins; C402930:FZD4 protein, human; D051157:Frizzled Receptors; C081848:NDP protein, human; D009419:Nerve Tissue Proteins