title: Results from the Registry of Atrial Fibrillation (AFABE): Gap between Undiagnosed and Registered Atrial Fibrillation in Adults--Ineffectiveness of Oral Anticoagulation Treatment with VKA.
abstract: OBJECTIVE
  This study aimed to examine the effectiveness of the use of oral anticoagulation (OAC) medication, recommended by national guidelines for stroke prevention but reportedly underused in AF patients with moderate to high stroke risk.
  
  
  METHODS
  A multicentre and cross-sectional study of undiagnosed AF among out-of-hospital patients over 60 years old was carried out, visiting 3,638 patients at primary health centres or at home for AF diagnosis using the IDC-10 classification. The main outcome measures were CHA₂DS₂VASC, HAS-BLED scores, cardiovascular comorbidity, pharmacological information, TTR, and SAMe-TT2R2 scores.
  
  
  RESULTS
  The main findings were undiagnosed AF in 26.44% of cases; 31.04% registered with AF but not using OAC despite 95.6% having a CHA₂DS₂VASC ≥ 2 score; a risk of bleeding in important subgroups using OAC without indication (37.50% CHA₂DS₂VASC < 2 score); the use of OAC with TTR < 60% (33.1%), of whom 47.6% had a HAS-BLED score ≥3. Thus, 35.4% of the expected AF prevalence achieved an optimal time in the therapeutic range.
  
  
  CONCLUSIONS
  The expected AF prevalence was 10.9% (n 5267), but the registered prevalence was 7.5% (n 3638). Only 35.04% (CI = 95%, 33.7-36.3) of AF patients treated with vitamin K antagonists (VKAs) achieve the goal of TTR > 60%.
authors.affiliation: EAP Tortosa 1-Oest, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Roquetes, 43520 Tortosa, Spain.
authors.forename: Anna
authors.initials: A
authors.lastname: Panisello-Tafalla
authors.affiliation: EAP Tortosa 1-Est, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Temple, 43500 Tortosa, Spain ; Miguel Hernández University, 03202 Elche, Spain.
authors.forename: Josep Lluís
authors.initials: JL
authors.lastname: Clua-Espuny
authors.affiliation: Miguel Hernández University, 03202 Elche, Spain.
authors.forename: Vicente F
authors.initials: VF
authors.lastname: Gil-Guillen
authors.affiliation: EAP-Camarles-Aldea-Ampolla, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Ampolla, 43895 Tortosa, Spain.
authors.forename: Antonia
authors.initials: A
authors.lastname: González-Henares
authors.affiliation: EAP Tortosa-2-Oest, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Xerta, 43592 Tortosa, Spain.
authors.forename: María Lluisa
authors.initials: ML
authors.lastname: Queralt-Tomas
authors.affiliation: Molecular Biology and Research Section, Hospital de Tortosa Verge de la Cinta, IISPV, IDIAP, 43500 Tortosa, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: López-Pablo
authors.affiliation: EAP Deltebre, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Deltebre, 43580 Tortosa, Spain.
authors.forename: Jorgina
authors.initials: J
authors.lastname: Lucas-Noll
authors.affiliation: Department of Cardiology, Hospital de Tortosa Verge de la Cinta, IISPV, 43500 Tortosa, Spain.
authors.forename: Iñigo
authors.initials: I
authors.lastname: Lechuga-Duran
authors.affiliation: EAP Tortosa 1-Est, Institut Català Salut, SAP Terres de l'Ebre, Health Department, Generalitat de Catalunya, CAP Temple, 43500 Tortosa, Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: Ripolles-Vicente
authors.affiliation: Department of Systems Management, Hospital de Tortosa Verge de la Cinta, Institut Català de la Salut, 43500 Tortosa, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Carot-Domenech
authors.affiliation: Pla Director de la Malaltia Vascular Cerebral de Catalunya, Department Salut de la Generalitat de Catalunya, 08005 Barcelona, Spain.
authors.forename: Miquel Gallofré
authors.initials: MG
authors.lastname: López
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D012042:Registries; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D016019:Survival Analysis; D014812:Vitamin K / Q000037:antagonists & inhibitors*
chemical_list: D000925:Anticoagulants; D014812:Vitamin K