title: The value of the Duke treadmill score in predicting the presence and severity of coronary artery disease.
abstract: OBJECTIVE
  We aimed to investigate the role of the Duke treadmill score (DTS) in predicting the presence and severity of coronary artery disease (CAD) by using the SYNTAX score (SS), and also to determine the cut-off value of DTS for both the presence and severity of CAD.
  
  
  METHODS
  The study population consisted of 267 patients admitted to the outpatient clinic with chest pain, who under-went coronary angiography after a positive treadmill stress test. First the patients were divided into two groups: SS = 0 and SS > 0. Then the SS > 0 patients were classified into two subgroups with low (1-22) and high (> 22) SS.
  
  
  RESULTS
  There was a strong negative correlation between DTS and SS (r = -072, p < 0.001). The area under the receiver-operating curve of DTS was 0.83 (0.77-0.88, p < 0.001) for predicting a significant presence of CAD. The optimal cut-off value of DTS to predict the significant presence of CAD was -3.7 (sensitivity of 74% and specificity of 73%). The area under the receiver-operating curve of DTS was 0.84 (0.78-0.90, p < 0.001) for predicting high SS. The optimal cut-off value of DTS to predict high SS was -11.2 (sensitivity of 81% and specificity of 80%). DTS was found to be an independent predictor of high SS in multivariate analysis.
  
  
  CONCLUSIONS
  DTS can predict the presence and severity of stable CAD before coronary angiography and may enable the estimation of the revascularisation method that will be required after the procedure.
authors.affiliation: Department of Cardiology, Ordu University, Ordu, Turkey. doktorzeki28@gmail.com.
authors.forename: Zeki Yüksel
authors.initials: ZY
authors.lastname: Günaydın
authors.forename: Osman
authors.initials: O
authors.lastname: Bektaş
authors.forename: Yusuf Emre
authors.initials: YE
authors.lastname: Gürel
authors.forename: Ahmet
authors.initials: A
authors.lastname: Karagöz
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kaya
authors.forename: Tuncay
authors.initials: T
authors.lastname: Kırış
authors.forename: Gönül
authors.initials: G
authors.lastname: Zeren
authors.forename: Selçuk
authors.initials: S
authors.lastname: Yazıcı
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000175:diagnosis*; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012720:Severity of Illness Index
keywords: Duke treadmill score; SYNTAX score; coronary angiography; coronary artery disease; exercise treadmill testing