title: Black Beans, Fiber, and Antioxidant Capacity Pilot Study: Examination of Whole Foods vs. Functional Components on Postprandial Metabolic, Oxidative Stress, and Inflammation in Adults with Metabolic Syndrome.
abstract: Beans (Phaseolus vulgaris) contain bioactive components with functional properties that may modify cardiovascular risk. The aims of this pilot study were to evaluate the ability of black beans to attenuate postprandial metabolic, oxidative stress, and inflammatory responses and determine relative contribution of dietary fiber and antioxidant capacity of beans to the overall effect. In this randomized, controlled, crossover trial, 12 adults with metabolic syndrome (MetS) consumed one of three meals (black bean (BB), fiber matched (FM), and antioxidant capacity matched (AM)) on three occasions that included blood collection before (fasting) and five hours postprandially. Insulin was lower after the BB meal, compared to the FM or AM meals (p < 0.0001). A significant meal × time interaction was observed for plasma antioxidant capacity (p = 0.002) revealing differences over time: AM > BB > FM. Oxidized LDL (oxLDL) was not different by meal, although a trend for declining oxLDL was observed after the BB and AM meals at five hours compared to the FM meal. Triglycerides and interleukin-6 (IL-6) increased in response to meals (p < 0.0001). Inclusion of black beans with a typical Western-style meal attenuates postprandial insulin and moderately enhances postprandial antioxidant endpoints in adults with MetS, which could only be partly explained by fiber content and properties of antioxidant capacity.
authors.affiliation: Department of Nutrition, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. ebjordan@ucdavis.edu.
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Reverri
authors.affiliation: Department of Nutrition, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. jmrandolph@ucdavis.edu.
authors.forename: Jody M
authors.initials: JM
authors.lastname: Randolph
authors.affiliation: Department of Nutrition, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. fmsteinberg@ucdavis.edu.
authors.forename: Francene M
authors.initials: FM
authors.lastname: Steinberg
authors.affiliation: Departments of Cardiovascular Medicine, Cardiology, and Internal Medicine, Lawrence J. Ellis Ambulatory Care Center, University of California, Davis Health System, 4680 Y Street, Suite 0200, Sacramento, CA 95817, USA.
authors.forename: C Tissa
authors.initials: CT
authors.lastname: Kappagoda
authors.affiliation: Center for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, 6502 South Archer Road, Bedford Park, IL 60501, USA. iedirisi@iit.edu.
authors.forename: Indika
authors.initials: I
authors.lastname: Edirisinghe
authors.affiliation: Department of Nutrition, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. bburton@iit.edu.|Center for Nutrition Research, Institute for Food Safety and Health, Illinois Institute of Technology, 6502 South Archer Road, Bedford Park, IL 60501, USA. bburton@iit.edu.
authors.forename: Britt M
authors.initials: BM
authors.lastname: Burton-Freeman
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000494:pharmacology* / Q000627:therapeutic use; D001786:Blood Glucose / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000517:prevention & control; D066273:Diet, Western; D004043:Dietary Fiber / Q000494:pharmacology* / Q000627:therapeutic use; D007887:Fabaceae / Q000737:chemistry*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood; D007328:Insulin / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D062407:Meals; D024821:Metabolic Syndrome / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D008875:Middle Aged; D018384:Oxidative Stress / Q000187:drug effects*; D010865:Pilot Projects; D019518:Postprandial Period / Q000187:drug effects; D012307:Risk Factors; D012639:Seeds; D014280:Triglycerides / Q000097:blood
chemical_list: D000975:Antioxidants; D001786:Blood Glucose; D004043:Dietary Fiber; C508600:IL6 protein, human; D007328:Insulin; D015850:Interleukin-6; D008077:Lipoproteins, LDL; D014280:Triglycerides; C099252:oxidized low density lipoprotein
keywords: antioxidant capacity; bean; fiber; metabolic syndrome; postprandial