title: The outcome of acute respiratory distress syndrome in relation to body mass index and diabetes mellitus.
abstract: OBJECTIVE
  To determine the 28 day mortality of patients with ARDS in relation to body mass index (BMI) and presence diabetes mellitus (DM).
  
  
  METHODS
  Retrospective cohort study of patients enrolled in the ARDS Network randomized controlled trials.
  
  
  RESULTS
  2914 patients were enrolled in these trials. 112 patients were underweight (BMI < 18.5), 948 patients were normal range (18.5 ≤ BMI < 25.0), 801 patients were overweight (25.0 ≤ BMI < 30.0), 687 patients were obese (30.0 ≤ BMI < 40.0), and 175 patients were severely obese (BMI ≥ 40.0). 469 patients had DM. There was no significant difference in the 28 day mortality in relation to BMI or presence of DM (underweight adjusted OR, 1.217; 95% CI, 0.749-1.979; overweight adjusted OR, 0.887; 95% CI, 0.696-1.131; obese adjusted OR, 0.812; 95% CI, 0.624-1.056; severely obese adjusted OR, 1.102; 95% CI, 0.716-1.695; and DM adjusted OR, 0.938; 95% CI, 0.728-1.208).
  
  
  CONCLUSIONS
  The short term mortality in patients with ARDS is not affected by BMI or the presence of DM.
authors.affiliation: Section of Pulmonary and Critical Care Medicine, Wayne State University School of Medicine, Detroit, MI, USA. Electronic address: asoubani@med.wayne.edu.
authors.forename: Ayman O
authors.initials: AO
authors.lastname: Soubani
authors.affiliation: Department of Oncology, Karmanos Cancer Center, Wayne State University School of Medicine, Detroit, MI, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
authors.affiliation: Department of Oncology, Karmanos Cancer Center, Wayne State University School of Medicine, Detroit, MI, USA.
authors.forename: Hyejeong
authors.initials: H
authors.lastname: Jang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D009767:Obesity, Morbid / Q000150:complications; D050177:Overweight / Q000150:complications; D011379:Prognosis; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000401:mortality*; D012189:Retrospective Studies; D055815:Young Adult
keywords: ARDS; BMI; Diabetes mellitus; Obesity; Outcome