title: Preliminary analysis of Plasmodium vivax genotypes isolated in southeastern Turkey.
abstract: Plasmodium vivax is the most common cause of malaria worldwide as well as southeastern Turkey. After the implementation of a successful national elimination program that the local malaria cases were not reported in 2011, malaria returned to county of Savur located in southeastern Turkey in summer of 2012. The present study aimed to determine the prevalent P. vivax genotypes isolated from southeastern Turkey. Genetic polymorphism in P. vivax CSP gene was analyzed by PCR-RFLP to assess the ratio of VK210 and VK247 types. Blood samples were obtained from 15 patients who lived in southeastern between 2005-2006. According to the results, VK210 type was detected in 10 samples (66.6%), VK247 type was observed in three samples (20%). Remaining two samples showed mixed infection (13.3%). The results of the present study first time showed the ratio of P. vivax genotypes in southeastern Turkey before the elimination in 2011. The results of the present study will be enable researchers to compare the new isolates with the previously detected ones and design new treatment and/elimination strategies.
authors.forename: Aysu Değirmenci
authors.initials: AD
authors.lastname: Döşkaya
authors.forename: Mert
authors.initials: M
authors.lastname: Döşkaya
authors.forename: Ayşe
authors.initials: A
authors.lastname: Caner
authors.forename: Kadri
authors.initials: K
authors.lastname: Gül
authors.forename: Şebnem
authors.initials: Ş
authors.lastname: Nergiz
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Can
authors.forename: Yüksel
authors.initials: Y
authors.lastname: Gürüz
mesh_terms: D016172:DNA Fingerprinting; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D016780:Malaria, Vivax / Q000453:epidemiology* / Q000469:parasitology*; D017720:Molecular Epidemiology; D010966:Plasmodium vivax / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D014421:Turkey / Q000453:epidemiology