title: Mesenchymal Hamartoma of the Liver in an Infant With Beckwith-Wiedemann Syndrome: A Rare Condition Mimicking Hepatoblastoma.
abstract: Patients with Beckwith-Wiedemann syndrome (BWS) are known to be at an increased risk for childhood malignancies, particularly Wilms tumor and hepatoblastoma. We report a case of genetically confirmed BWS in a 5-month-old girl who presented with a 9.5-cm abdominal mass associated with elevated α-fetoprotein levels. The clinical impression was strongly suggestive of hepatoblastoma. Histologic examination of the surgically excised mass revealed mesenchymal hamartoma of the liver (MHL), a benign hepatic neoplasm.
authors.affiliation: Department of Pathology, Barretos Cancer Hospital, Barretos, São Paulo, Brazil ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
authors.forename: Lucas F
authors.initials: LF
authors.lastname: Abrahao-Machado
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN ; Department of Pathology, Hospital Federal de Ipanema, Rio de Janeiro, Brazil.
authors.forename: Fabiane C
authors.initials: FC
authors.lastname: de Macedo
authors.affiliation: Department of Pathology, St. Joseph's Hospital, Tampa, FL.
authors.forename: Carlos
authors.initials: C
authors.lastname: Dalence
authors.affiliation: Department of Radiology, St. Joseph's Hospital, Tampa, FL.
authors.forename: Glenn
authors.initials: G
authors.lastname: Stambo
authors.affiliation: Jundiai Medical College, Jundiai, São Paulo, Brazil.
authors.forename: Eduarda F
authors.initials: EF
authors.lastname: Abrahao-Machado
authors.affiliation: Catholic University of Campinas, Campinas, São Paulo, Brazil.
authors.forename: Elaine C F
authors.initials: EC
authors.lastname: Abrahao-Machado
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
authors.forename: Armita
authors.initials: A
authors.lastname: Bahrami
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
authors.forename: Antonio G
authors.initials: AG
authors.lastname: Nascimento