title: Trichoscopic changes in hair during treatment of hirsutism with 1064-nm neodymium:yttrium-aluminum-garnet laser.
abstract: BACKGROUND
  Laser hair removal has become an accepted form of long-term hair reduction and is now one of the most common dermatologic procedures. Trichoscan is a validated method of assessing hair length, thickness, and density and growth rate using dermoscopy.
  
  
  OBJECTIVE
  The study aimed to evaluate the trichoscopic changes during treatment of hirsutism with 1064-nm neodymium:yttrium-aluminum-garnet laser.
  
  
  METHODS
  Seventy patients with idiopathic facial hirsutism referring to the laser centers of Al-Azhar University hospital (Asyut and Cairo) between December 2012 and October 2014 were enrolled in this open-label, multicentric study. All participants received six sessions of 1064-nm Nd:YAG laser at 4-week intervals. Mean hair density/cm(2) , percentage of terminal/vellus hair ratio, and hair thickness (mm) were assessed at baseline and 1 month after each session for six sessions using trichoscan.
  
  
  RESULTS
  Seventy female patients completed the study protocol. At the final visit, mean hair density, terminal/vellus hair ratio, and hair thickness were significantly decreased from baseline (73.7 + 20.6, 72.5 + 14.7, 0.095 + 0.02, respectively) to (19.4 + 5.6, 21.3 + 5.2, 0.02 ± 0.007, respectively) (P < 0.05 for each).
  
  
  CONCLUSIONS
  One thousand and sixty-four-nm Nd:YAG laser is an effective and safe method in the reduction of unwanted facial hair. Trichoscan is an easy and more accurate method in monitoring the treatment of hair disorders.
authors.affiliation: Dermatology and Andrology Department, Al-Azhar University Hospital, Asyut, Egypt.
authors.forename: Essam-Elden Mohamed
authors.initials: EE
authors.lastname: Mohamed
authors.affiliation: Dermatology and Andrology Department, Al-Azhar University Hospital, Asyut, Egypt.
authors.forename: Amer Mohamed
authors.initials: AM
authors.lastname: Ahmed
authors.affiliation: Dermatology and Andrology Department, Al-Azhar University Hospital, Asyut, Egypt.
authors.forename: Khaled Mohamed
authors.initials: KM
authors.lastname: Tawfik
authors.affiliation: Dermatology and Venereology Department, Al-Azhar University Hospital, Cairo, Egypt.
authors.forename: Shady Mahmoud
authors.initials: SM
authors.lastname: Ibrahim
mesh_terms: D000328:Adult; D046169:Dermoscopy; D005145:Face; D005260:Female; D006197:Hair / Q000000981:diagnostic imaging* / Q000528:radiation effects*; D006204:Hair Removal; D006628:Hirsutism / Q000532:radiotherapy*; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D055815:Young Adult
keywords: Nd:YAG laser; dermoscopy; hirsutism; trichoscopy