title: Bilateral microphthalmos with cyst in a neonatal foal.
abstract: A 1-day-old miniature horse filly was presented to the University of Florida Veterinary Ophthalmology service for evaluation of multiple ocular anomalies which were present from birth. Protruding from the right orbit was a large, fluctuant, red, dry and variably ulcerated mass. A globe could not be appreciated clinically in the left orbit. Ocular ultrasound of both orbits was performed. This revealed a lobular, hypo-echoic structure filling the right orbit, with multiple hyperechoic septations; normal ocular structures were not identified. Ultrasound of the left orbit revealed a microphthalmic eye, with a well-defined, hyperechoic structure in the vitreous that was thought to be the lens. Due to irreversible blindness, the foal was humanely euthanized. Histopathology and immunohistochemistry of the orbital contents revealed bilateral microphthalmos with cyst, a congenital defect rarely reported in the veterinary literature.
authors.affiliation: Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610-0126, USA.
authors.forename: Shari M
authors.initials: SM
authors.lastname: Greenberg
authors.affiliation: Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610-0126, USA.
authors.forename: Caryn E
authors.initials: CE
authors.lastname: Plummer
authors.affiliation: Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610-0126, USA.
authors.forename: Dodd
authors.initials: D
authors.lastname: Sledge
authors.affiliation: Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610-0126, USA.
authors.forename: Misa
authors.initials: M
authors.lastname: Komine
authors.affiliation: Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610-0126, USA.
authors.forename: Serena L
authors.initials: SL
authors.lastname: Craft
authors.affiliation: Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610-0126, USA.
authors.forename: Julia A
authors.initials: JA
authors.lastname: Conway
keywords: cataract; coloboma; cystic globe; eye; microphthalmos with cyst; miniature foal