title: [From FRANCE 2 to FRANCE TAVI: are indications, technique and results of transcatheter aortic valve replacement the same?].
abstract: Transcatheter aortic valve implantation (TAVI) is indicated in patients with severe symptomatic aortic stenosis who are not suitable for surgery or should be considered when there is a high surgical risk as assessed by a heart team. There is a decrease in mean logistic EuroSCORE since January 2010, which translates a gradual evolution in patients' selection. Expertise of geriatricians to further assess frailty is a key step in the risk stratification process of this elderly population (mean age: 83.4±7.3 years). Femoral access is used in 80% of cases with a procedural success rate higher than 95%. In-hospital mortality rate is 5.9%. The main complications of the procedure are aortic annulus rupture (0.9% in FRANCE TAVI), tamponade (2.3%), stroke (2.2%), severe paravalvular leak (1.3%) and permanent pacemaker implantation (15%). The awaited results of PARTNER II and SURTAVI may lead to expand the indications to lower-risk patients if it is shown that TAVI is non-inferior to surgery in this population which has been suggested by the recent randomized NOTION Trial while the CoreValve Pivotal Trial even points in the direction of a possible superiority of the percutaneous technique over surgery.
authors.affiliation: CHU de Rennes, service de cardiologie et des maladies vasculaires, 35000 Rennes, France; Université Rennes 1, LTSI, 35000 Rennes, France; Inserm U1099, 35000 Rennes, France. Electronic address: vincent.auffret@chu-rennes.fr.
authors.forename: Vincent
authors.initials: V
authors.lastname: Auffret
authors.affiliation: CHU de Rennes, service de cardiologie et des maladies vasculaires, 35000 Rennes, France; Université Rennes 1, LTSI, 35000 Rennes, France; Inserm U1099, 35000 Rennes, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Bedossa
authors.affiliation: CHU de Rennes, service de cardiologie et des maladies vasculaires, 35000 Rennes, France; Université Rennes 1, LTSI, 35000 Rennes, France; Inserm U1099, 35000 Rennes, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Boulmier
authors.affiliation: Université Rennes 1, LTSI, 35000 Rennes, France; Inserm U1099, 35000 Rennes, France; CHU de Rennes, service de chirurgie thoracique et cardiovasculaire, 35000 Rennes, France.
authors.forename: Jean Philippe
authors.initials: JP
authors.lastname: Verhoye
authors.affiliation: Université Rennes 1, LTSI, 35000 Rennes, France; Inserm U1099, 35000 Rennes, France; CHU de Rennes, service de chirurgie thoracique et cardiovasculaire, 35000 Rennes, France.
authors.forename: Vito Giovanni
authors.initials: VG
authors.lastname: Ruggieri
authors.affiliation: Clinique Saint-Hilaire, service de cardiologie, 76000 Rouen, France.
authors.forename: René
authors.initials: R
authors.lastname: Koning
authors.affiliation: CHU de Limoges, département de chirurgie cardiovasculaire, 87000 Limoges, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Laskar
authors.affiliation: Université Lille 2, CHRU de Lille, département de cardiologie, Inserm U1011, FHU Integra, 59000 Lille, France.
authors.forename: Éric
authors.initials: É
authors.lastname: Van Belle
authors.affiliation: Université Sorbonne - Pierre-et-Marie-Curie, AP-HP, GHPS, chirurgie cardiaque, 75005 Paris, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Leprince
authors.affiliation: AP-HP, CHU La Pitié-Salpêtrière, service de cardiologie, 75013 Paris, France.
authors.forename: Jean Philippe
authors.initials: JP
authors.lastname: Collet
authors.affiliation: DHU Fire et université Paris-Diderot, AP-HP, hôpital Bichat, département de cardiologie, 75018 Paris, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Iung
authors.affiliation: Institut cardiovasculaire Paris-Sud, hôpital privé Jacques-Cartier, 91300 Massy, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Lefèvre
authors.affiliation: CHU Rouen - Charles-Nicolle, Inserm U644, 76031 Rouen, France.
authors.forename: Helene
authors.initials: H
authors.lastname: Eltchaninoff
authors.affiliation: CHU de Brest, La Cavale-Blanche, 29200 Brest France.
authors.forename: Martine
authors.initials: M
authors.lastname: Gilard
authors.affiliation: CHU de Rennes, service de cardiologie et des maladies vasculaires, 35000 Rennes, France; Université Rennes 1, LTSI, 35000 Rennes, France; Inserm U1099, 35000 Rennes, France.
authors.forename: Hervé
authors.initials: H
authors.lastname: Le Breton
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000453:epidemiology / Q000601:surgery*; D005260:Female; D016330:Frail Elderly / Q000706:statistics & numerical data; D005602:France / Q000453:epidemiology; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D018579:Patient Selection; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D016032:Randomized Controlled Trials as Topic; D065467:Transcatheter Aortic Valve Replacement / Q000379:methods* / Q000706:statistics & numerical data*