title: Multivariate Analysis of Relationship between Childhood Trauma and Psychotic Symptoms in Patients with Schizophrenia.
abstract: The aim of this study was to examine the relationship between childhood trauma and psychotic symptoms in schizophrenic patients after controlling for the possible confounding factors, such as depression and dissociative symptoms. Ninety-eight schizophrenic inpatients participated. Childhood trauma was examined using the Childhood Trauma Questionnaires (CTQ), which consists of physical abuse (PA), sexual abuse (SA), emotional abuse (EA), physical neglect (PN), and emotional neglect (EN). Positive and Negative Syndrome Scale (PANSS), Dissociative Experience Scale (DES), and Beck's Depression Inventory (BDI) were also administered. Data were analyzed by partial correlation and general linear model. The total score of CTQ was positively correlated with positive, general, and total scores of PANSS. All five types of childhood trauma were associated with dissociative symptoms. EA and EN were positively correlated with depressive symptoms. Only SA significantly predicted positive symptoms of schizophrenia after controlling for age, sex, BDI, and DES scores, with a dose-response relationship between SA and positive symptoms.
authors.affiliation: Department of Psychiatry, Seoul National Hospital, Seoul, Republic of Korea.
authors.forename: Sungun
authors.initials: S
authors.lastname: Chae
authors.affiliation: Department of Psychiatric Rehabilitation, Seoul National Hospital, Seoul, Republic of Korea. ; Psychological Trauma Center, Seoul National Hospital, Seoul, Republic of Korea.
authors.forename: Minyoung
authors.initials: M
authors.lastname: Sim
authors.affiliation: Department of Psychiatry, Seoul National Hospital, Seoul, Republic of Korea.
authors.forename: Mijeong
authors.initials: M
authors.lastname: Lim
authors.affiliation: Department of Emergency Medicine, Asan Chungmu Hospital, Asan, Republic of Korea.
authors.forename: Joonho
authors.initials: J
authors.lastname: Na
authors.affiliation: Department of Psychiatry, Hanyang University Medical School, Seoul, Republic of Korea.
authors.forename: Daeho
authors.initials: D
authors.lastname: Kim
keywords: Childhood trauma; Positive symptom; Schizophrenia; Sexual abuse