title: Dual band dual focus optical coherence tomography for imaging the whole eye segment.
abstract: We developed an improved dual band dual focus spectral domain optical coherence tomography (SD-OCT) for in vivo 2D/3D imaging of the whole eye segment, including the whole anterior segment and retina. The system featured two OCT channels with two different bands centered at 840 nm and 1050 nm, which were designed to image the retina and the anterior segments of the eye, respectively. By combing the two probe light beams for co-axial scanning and separating them for focusing at different segments of the eye with a combination of three dichroic mirrors, we not only minimized the loss of the backscattered light from the sample but also improved the imaging depth, scan range and resolution. The full resolved complex (FRC) method was applied to double the imaging depth for the whole anterior segment imaging, with which an imaging depth of 36.71 mm in air was achieved. We demonstrated that this system was capable of measuring the dynamic changes of ocular dimensions, including the asphericity of the cornea and lens, during accommodation.
authors.affiliation: School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
authors.forename: Shanhui
authors.initials: S
authors.lastname: Fan
authors.affiliation: School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Li
authors.affiliation: School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.affiliation: School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
authors.forename: Cuixia
authors.initials: C
authors.lastname: Dai
authors.affiliation: Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, 100871, China.
authors.forename: Qiushi
authors.initials: Q
authors.lastname: Ren
authors.affiliation: Department of Biomedical Engineering, Florida International University, Miami, FL, 33174, USA ; shjiao@fiu.edu.
authors.forename: Shuliang
authors.initials: S
authors.lastname: Jiao
authors.affiliation: School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
authors.forename: Chuanqing
authors.initials: C
authors.lastname: Zhou
keywords: (110.4500) Optical coherence tomography; (170.3880) Medical and biological imaging; (170.4460) Ophthalmic optics and devices; (170.4470) Ophthalmology; (170.4500) Optical coherence tomography; (330.7322) Visual optics, accommodation