title: [Serum Levels of Regulatory T Cell in the Yusho Patients].
abstract: Dioxin and dioxin-like compounds receptor (Ahr) mainly expressed on the surface of regulatory T (Treg) cell and Th17 cell could regulate immunological functions in the Yusho patients. We prospectively analyzed data obtained in a total of 56 cases of Yusho, which include patients identified ('Nintei' ) or non-identified ( 'Minintei') or identified as a family member, at the annual health check in 2014. The number of Treg cell showed lower among identified patients compared with non-identified group or family identified group (p = 0.4184 and p = 0.291, respectively). There was also a strong correlation between serum levels of neutral fat and the number of Treg cells (p = 0.0313). These results suggest that Treg cell plays a principal role in the immune response among Yusho patients.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Mine
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kuwatsuka
authors.forename: Atsushi
authors.initials: A
authors.lastname: Utani
mesh_terms: D000368:Aged; D006801:Humans; D011164:Porphyrias / Q000097:blood / Q000276:immunology*; D011446:Prospective Studies; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*