title: Expression of ARs in triple negative breast cancer tumors: a potential prognostic factor?
abstract: OBJECTIVE
  In light of the controversial published literature, this study aims to examine the potential prognostic role of AR immunohistochemical expression in triple negative breast cancer (TNBC).
  
  
  METHODS
  Ninety patients with TNBC were included in this study; the associations between AR expression (Allred score), clinicopathological variables (stage, grade, histological subtype, tumor size, nodal status, age at diagnosis, Ki67 expression, and p53 expression), and overall survival were evaluated.
  
  
  RESULTS
  AR expression was not associated with stage, grade, histological subtype, tumor size, nodal status, age at diagnosis, Ki67 expression, and p53 expression. AR immunopositivity was not associated with overall survival either at the univariate or at the multivariate Cox regression analysis (multivariate hazard ratio =0.66, 95% confidence interval: 0.26-1.70, P=0.393).
  
  
  CONCLUSIONS
  AR expression does not seem to play a prognostic role in TNBC.
authors.affiliation: Department of Obstetrics and Gynaecology, Alexandra General Hospital, Medical School, University of Athens, Athens, Greece.
authors.forename: Aris
authors.initials: A
authors.lastname: Giannos
authors.affiliation: Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
authors.forename: Martin
authors.initials: M
authors.lastname: Filipits
authors.affiliation: Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria ; Department of Clinical Therapeutics, Alexandra General Hospital, Medical School, University of Athens, Athens, Greece.
authors.forename: Flora
authors.initials: F
authors.lastname: Zagouri
authors.affiliation: Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
authors.forename: Anita
authors.initials: A
authors.lastname: Brandstetter
authors.affiliation: Department of Obstetrics and Gynaecology, Alexandra General Hospital, Medical School, University of Athens, Athens, Greece.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Tsigginou
authors.affiliation: Department of Pathology, Alexandra General Hospital, Athens, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Sotiropoulou
authors.affiliation: Department of Pathology, Alexandra General Hospital, Athens, Greece.
authors.forename: Irene
authors.initials: I
authors.lastname: Papaspyrou
authors.affiliation: Department of Hygiene, Epidemiology and Medical Statistics, Medical School, University of Athens, Athens, Greece.
authors.forename: Theodoros N
authors.initials: TN
authors.lastname: Sergentanis
authors.affiliation: Department of Hygiene, Epidemiology and Medical Statistics, Medical School, University of Athens, Athens, Greece.
authors.forename: Theodora
authors.initials: T
authors.lastname: Psaltopoulou
authors.affiliation: Department of Obstetrics and Gynaecology, Alexandra General Hospital, Medical School, University of Athens, Athens, Greece.
authors.forename: Alexandros
authors.initials: A
authors.lastname: Rodolakis
authors.affiliation: Department of Obstetrics and Gynaecology, Alexandra General Hospital, Medical School, University of Athens, Athens, Greece.
authors.forename: Aris
authors.initials: A
authors.lastname: Antsaklis
authors.affiliation: Institute of Cancer Research, Department of Medicine I, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
authors.forename: Meletios-Athanasios
authors.initials: MA
authors.lastname: Dimopoulos
authors.affiliation: Department of Obstetrics and Gynaecology, Alexandra General Hospital, Medical School, University of Athens, Athens, Greece.
authors.forename: Constantine
authors.initials: C
authors.lastname: Dimitrakakis
keywords: AR; biomarkers; prognosis; triple negative breast cancer