title: Leydig cell hyperplasia in the setting of Klinefelter syndrome.
abstract: A man in his 20's with Klinefelter syndrome presented to the urology clinic with a recent history of left-sided orchalgia. Ultrasound evaluation demonstrated multiple small hypoechoic lesions bilaterally, with the largest lesion measured at 5 mm × 6 mm × 8 mm. Testis cancer tumour markers, chest radiographs and abdominal CT imaging were negative. A partial orchiectomy was performed on the largest lesion, demonstrating the presence of Leydig cell hyperplasia.
authors.affiliation: Department of Urology, Tripler Army Medical Center, Honolulu, Hawaii, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Sterbis
authors.affiliation: Tripler Army Medical Center, Tripler, Hawaii, USA.
authors.forename: Toritsetimiyin
authors.initials: T
authors.lastname: E-Nunu
mesh_terms: D000328:Adult; D006801:Humans; D006965:Hyperplasia / Q000150:complications / Q000175:diagnosis; D007713:Klinefelter Syndrome / Q000150:complications*; D007985:Leydig Cells / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D013733:Testicular Diseases / Q000150:complications / Q000000981:diagnostic imaging*; D014463:Ultrasonography