title: Brainstem auditory evoked potential in clinical hypothyroidism.
abstract: OBJECTIVE
  The association of hypothyroidism with impairment of hearing is known to occur. It may be of any kind i. e., conductive, sensorineural or mixed. The aim of this study is to assess auditory pathway by brainstem auditory evoked potential (BAEP) in newly diagnosed patients of clinical hypothyroidism and healthy sex- and age-matched controls.
  
  
  METHODS
  The study included 25 healthy age- and sex-matched controls (Group I) and 25 patients of newly diagnosed clinical hypothyroidism (Group II). The recording was taken by using RMS EMG EP MK2 equipment.
  
  
  METHODS
  Unpaired Student's t test.
  
  
  RESULTS
  There was a significant increase in wave IV (5.16 ± 0.85 ms) and wave V (6.17 ± 0.89 ms) latencies of right ear BAEP of Group II in comparison to wave IV (4.66 ± 0.39 ms) and wave V (5.49 ± 0.26 ms) of Group I. Wave V of left ear BAEP of Group II was also prolonged (6 ± 0.61 ms) in comparison to Group I (5.47 ± 0.35 ms). There was a significant difference in inter-peak latencies IPL I -V (4.44 ± 0.66 ms) and IPL III -V (2.2 ± 0.5 ms) of right ear BAEP of Group II in comparison to IPL I -V (3.94 ± 0.31 ms) and IPL III -V (1.84 ± 0.34 ms) of Group I. A significant prolongation was also found of IPL I -V (4.36 ± 0.59 ms) and IPL III -V (2.2 ± 0.42 ms) of left ear BAEP of Group II in comparison to IPL I -V (3.89 ± 0.3 ms) and IPL III -V (1.85 ± 0.3 ms) of Group I.
  
  
  CONCLUSIONS
  Prolongation of wave IV and V along with inter-peak latencies in BAEP of both ears suggests that central auditory pathway is affected significantly in clinical hypothyroid patients.
authors.affiliation: Department of Physiology, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Mewat, India.
authors.forename: Kirti
authors.initials: K
authors.lastname: Sharma
authors.affiliation: Department of Physiology, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Mewat, India.
authors.forename: Naresh
authors.initials: N
authors.lastname: Kumar
authors.affiliation: Department of Physiology, Government Medical College, Srinagar, Pauri Garhwal, Uttarakhand, India.
authors.forename: Joshil Kumar
authors.initials: JK
authors.lastname: Behera
authors.affiliation: Department of Physiology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.
authors.forename: Sushma
authors.initials: S
authors.lastname: Sood
authors.affiliation: Department of Physiology, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Mewat, India.
authors.forename: Sibadatta
authors.initials: S
authors.lastname: Das
authors.affiliation: Department of Orthopedics, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Mewat, India.
authors.forename: Harnam Singh
authors.initials: HS
authors.lastname: Madan
keywords: BAEP; clinical hypothyroidism; hearing impairment