title: Uncovering a Role for SK2 in Angelman Syndrome.
abstract: Angelman syndrome is a severe neurodevelopmental disorder caused by mutations in UBE3A. Sun et al. (2015) report SK2 as a UBE3A substrate and provide insight into the molecular mechanisms that might underlie impaired neuronal function in individuals affected by Angelman syndrome.
authors.affiliation: Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA; Center for Childhood Neurotherapeutics, University of South Carolina, Columbia SC 29208, USA. Electronic address: lizarras@mailbox.sc.edu.
authors.forename: Sofia B
authors.initials: SB
authors.lastname: Lizarraga
authors.affiliation: Department of Molecular Biology, Cell Biology and Biochemistry, Brown Institute for Brain Science and Laboratories for Molecular Medicine, Brown University, 70 Ship Street, Providence, RI 02912, USA; Developmental Disorders Genetics Research Program, Emma Pendleton Bradley Hospital, 1011 Veterans Memorial Parkway, East Providence, RI 02912, USA; Department of Psychiatry and Human Behavior, Alpert Medical School, Brown University, Providence, RI 02912, USA. Electronic address: eric_morrow@brown.edu.
authors.forename: Eric M
authors.initials: EM
authors.lastname: Morrow
mesh_terms: D000818:Animals; D007858:Learning / Q000502:physiology*; D008297:Male; D008568:Memory / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*; D051640:Small-Conductance Calcium-Activated Potassium Channels / Q000378:metabolism*; D044767:Ubiquitin-Protein Ligases / Q000502:physiology*
chemical_list: D051640:Small-Conductance Calcium-Activated Potassium Channels; D044767:Ubiquitin-Protein Ligases