title: Comparative Analysis of the Anesthetic Efficacy of 0.5 and 0.75 % Ropivacaine for Inferior Alveolar Nerve Block in Surgical Removal of Impacted Mandibular Third Molars.
abstract: BACKGROUND
  Ropivacaine belongs to pipecoloxylidide group of local anesthetics. There are reports supporting the use of ropivacaine as a long acting local anesthetic in oral and maxillofacial surgical procedures, with variable data on the concentration that is clinically suitable.
  
  
  METHODS
  A prospective randomized double-blind study protocol was undertaken to assess the efficacy of 0.5 and 0.75 % ropivacaine for inferior alveolar nerve block in surgical extraction of impacted mandibular third molars. A total of 60 procedures were performed, of which thirty patients received 0.5 % and thirty received 0.75 % concentration of the study drug.
  
  
  RESULTS
  All the patients in both the study groups reported subjective numbness of lip and tongue. The time of onset was longer for 0.5 % ropivacaine when compared to 0.75 % solution. 90 % of the study patients in 0.5 % ropivacaine group reported pain corresponding to VAS ≥3 during bone guttering and 93.3 % patients reported pain corresponding to VAS >4 during tooth elevation. None of the patients in 0.75 % ropivacaine group reported VAS >3 at any stage of the surgical procedure. The duration of soft tissue anesthesia recorded with 0.75 % ropivacaine was average 287.57 ± 42.0 min.
  
  
  CONCLUSIONS
  0.75 % ropivacaine was found suitable for inferior alveolar nerve blocks in surgical extraction of impacted mandibular third molars.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Peoples College of Dental Sciences and Research Center, Peoples University, Bhanpur, Bhopal, MP India ; H-3/2, B.D.A Colony, Nayapura, Lal Ghati, Airport Road, Bhopal, 462031 MP India.
authors.forename: Darpan
authors.initials: D
authors.lastname: Bhargava
authors.affiliation: Department of Anesthesiology, L.N Medical College and Research Center and J.K Hospital, J.K Town, Sarvdharm C-Sector, Kolar Road, Bhopal, MP India.
authors.forename: Nupur
authors.initials: N
authors.lastname: Chakravorty
authors.affiliation: Department of Oral and Maxillofacial Surgery, Vinayaka Mission's Sankarachariyar Dental College and Hospital, Ariyanoor, Salem, TN India.
authors.forename: Elangovan
authors.initials: E
authors.lastname: Rethish
authors.affiliation: Department of Oral Medicine and Radiology, People's Dental Academy, People's Campus, Bhanpur, Bhopal, 462037 MP India.
authors.forename: Ashwini
authors.initials: A
authors.lastname: Deshpande
keywords: Dental; Inferior alveolar nerve block; Local anesthesia; Oral surgery; Ropivacaine