title: Spectrum of Eosinophilic End-Organ Manifestations.
abstract: Eosinophil-associated disorders can affect practically all tissues and organs in the body, either individually or in combination. This article provides an overview of end-organ manifestations of eosinophilia and discusses selected organ systems, including the upper and lower respiratory, cardiovascular, gastrointestinal, nervous, dermatologic, and renal systems. Mechanisms by which eosinophilia leads to end-organ damage are also considered.
authors.affiliation: Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA; Division of Allergy and Inflammation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA. Electronic address: pakuthot@bidmc.harvard.edu.
authors.forename: Praveen
authors.initials: P
authors.lastname: Akuthota
authors.affiliation: Division of Allergy and Inflammation, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA; Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
authors.forename: Peter F
authors.initials: PF
authors.lastname: Weller
mesh_terms: D004802:Eosinophilia / Q000473:pathology*; D004804:Eosinophils / Q000473:pathology; D005355:Fibrosis / Q000473:pathology*; D041981:Gastrointestinal Tract / Q000276:immunology / Q000473:pathology; D006801:Humans; D008168:Lung / Q000276:immunology / Q000473:pathology; D009206:Myocardium / Q000276:immunology / Q000473:pathology; D013927:Thrombosis / Q000473:pathology*
keywords: Churg-Strauss syndrome; Eosinophilic esophagitis; Eosinophilic granulomatous vasculitis; Eosinophils immunology; Eosinophils pathology; Humans; Hypereosinophilic syndrome; Pulmonary eosinophilia