title: Effectiveness of Hexetidine 0.1% in Eliminating Candida albicans Colonizing Dentures: A Randomized Clinical In Vivo Study.
abstract: BACKGROUND
  Effective cleaning of dentures is important to maintain a good oral hygiene for patients suffering from denture stomatitis (DS). This study aimed to evaluate the efficacy of hexetidine 0.1% in eliminating C. albicans colonizing dentures.
  
  
  METHODS
  A total of 40 denture wearers (18 men, 22 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 groups, 1 test, and 1 control. The dentures of the test group were treated by immersion in hexetidine 0.1% while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.
  
  
  RESULTS
  Reduction in the number of colony-forming units (CFU) of C. albicans after immersion of the dentures with hexetidine 0.1% was evaluated compared to those of the control group.
  
  
  CONCLUSIONS
  Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days.
authors.affiliation: Assistant Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon.
authors.forename: Georges
authors.initials: G
authors.lastname: Aoun
authors.affiliation: Professor, Department of Oral and Maxillofacial Imaging, School of Dentistry, Lebanese University, Beirut, Lebanon.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Nasseh
authors.affiliation: Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut, Lebanon ; Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut, Lebanon.
authors.forename: Maria
authors.initials: M
authors.lastname: Saadeh
authors.affiliation: Associate Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon.
authors.forename: Antoine
authors.initials: A
authors.lastname: Cassia
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut, Lebanon.
authors.forename: Antoine
authors.initials: A
authors.lastname: Berberi
keywords: Candida albicans; denture stomatitis; hexetidine