title: Electrochemical detection of single E. coli bacteria labeled with silver nanoparticles.
abstract: A proof-of-concept for the electrochemical detection of single Escherichia coli bacteria decorated with silver nanoparticles is reported. Impacts of bacteria with an electrode - held at a suitably oxidizing potential - lead to an accompanying burst of current with each collision event. The frequency of impacts scales with the concentration of bacteria and the charge indicates the extent of decoration.
authors.affiliation: Department of Chemistry, Physical & Theoretical Chemistry Laboratory, Oxford University, South Parks Road, Oxford OX1 3QZ, UK. richard.compton@chem.ox.ac.uk.
authors.forename: Lior
authors.initials: L
authors.lastname: Sepunaru
authors.forename: Kristina
authors.initials: K
authors.lastname: Tschulik
authors.forename: Christopher
authors.initials: C
authors.lastname: Batchelor-McAuley
authors.forename: Rachel
authors.initials: R
authors.lastname: Gavish
authors.forename: Richard G
authors.initials: RG
authors.lastname: Compton
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D004566:Electrodes; D004926:Escherichia coli / Q000737:chemistry* / Q000378:metabolism; D053768:Metal Nanoparticles / Q000737:chemistry*; D010084:Oxidation-Reduction; D012834:Silver / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver