title: Prevalence of post-operative morbidity risk factors following cardiac surgery in patients with chronic viral hepatitis: a retrospective study.
abstract: OBJECTIVE
  Current cardiac risk assessments such as EuroSCORE II and the STS-Score do not take liver dysfunction into account. The purpose of this study was to evaluate the prevalence and post-operative morbidity risk factors following cardiac surgery of patients with chronic viral hepatitis.
  
  
  METHODS
  The study group consisted of 105 patients with documented chronic viral hepatitis who were subject to elective cardiac surgery from 2001 to 2012. Subjects were evaluated for pre-operative liver dysfunction according to the MELD score.
  
  
  RESULTS
  The average MELD score of the study group was 10.00 ± 6.00. The average EuroSCORE ii of the study group was 2.07% ± 1.62%. The primary post-operative complication was cardiac complications (n=57, 54.3%). Analysis showed significant differences in meld score, bilirubin and smoking. Multivariate logistic regression analysis showed that the variables entering into the model included such risk factors with a significant or near significant (p < 0.2) influence on hospital morbidity and consisted in valve vs. coronary artery disease, valve/cad, aortic valve replacement vs. Coronary artery bypass graft, and bilirubin (mg/dl).
  
  
  CONCLUSIONS
  it is vital that liver dysfunction is added to the risk models which are currently utilized to predict the post-operative morbidity of cardiac surgery patients.
authors.affiliation: Department of Cardiovascular Surgery, Institute of Cardiovascular Diseases "Prof Dr. George IM Georgescu", Iasi, Romania; "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania. dr.hsieh520@gmail.com.
authors.forename: W C
authors.initials: WC
authors.lastname: Hsieh
authors.forename: P C
authors.initials: PC
authors.lastname: Chen
authors.forename: G
authors.initials: G
authors.lastname: George
authors.forename: G
authors.initials: G
authors.lastname: Tinica
authors.forename: F-C
authors.initials: FC
authors.lastname: Corciova
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D002908:Chronic Disease; D001026:Coronary Artery Bypass / Q000009:adverse effects; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects; D006525:Hepatitis, Viral, Human / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors