title: Quantiferon-Gold Tuberculosis Test Cannot Detect Latent Tuberculosis in Patients With Leprosy.
abstract: Five of 10 paucibacillary leprosy patients were Quantiferon Gold (Q-G) positive with negative chest X-rays. Forty multibacillary leprosy patients were negative. Reports have shown 100% cross-reactivity of ESAT6 and CFP10 between Mycobacterium leprae and Mycobacterium tuberculosis. The Q-G test cannot detect latent tuberculosis in patients with leprosy.
authors.affiliation: Bellevue Hospital Center, New York Hansen's Disease Program, New York.
authors.forename: Tina
authors.initials: T
authors.lastname: Rendini
authors.affiliation: Bellevue Hospital Center, New York Hansen's Disease Program, New York.
authors.forename: William
authors.initials: W
authors.lastname: Levis
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology; D003429:Cross Reactions; D003951:Diagnostic Errors; D006801:Humans; D059425:Interferon-gamma Release Tests / Q000379:methods*; D055985:Latent Tuberculosis / Q000175:diagnosis*; D007918:Leprosy / Q000150:complications*; D009166:Mycobacterium leprae / Q000276:immunology; D009169:Mycobacterium tuberculosis / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial
keywords: Quantiferon gold; leprosy; tuberculosis