title: PERIPHERAL RETINAL DEGENERATIONS AND RHEGMATOGENOUS DETACHMENT IN PRIMARY CONGENITAL GLAUCOMA.
abstract: BACKGROUND
  To determine the prevalence of peripheral retinal degenerations (PRD) and rhegmatogenous retinal detachment in patients with primary congenital glaucoma (PCG).
  
  
  METHODS
  Records of all patients with PCG operated from year 2000 onwards were evaluated to look for the prevalence of rhegmatogenous retinal detachment. Of these, those children who were old enough to cooperate and had sufficient medial clarity were screened with an indirect ophthalmoscopy in a cross-sectional evaluation from 2010 to 2014. Peripheral retina was examined, and prevalence of PRD was estimated in this subset. For statistical purposes, only one eye of each patient was considered in this cross-sectional analysis.
  
  
  RESULTS
  Of the 310 eyes (180 patients with PCG) operated from the year 2000 onwards, a rhegmatogenous retinal detachment was noted in 13 eyes (4%). Mean axial length of these eyes was 26.3 ± 3.2 mm (range, 19.8-34.7 mm). Among the eyes screened for PRD (n = 60), prevalence of pathologic PRD (lattices with/without atrophic holes and isolated holes/tears) was 15%. The average follow-up between glaucoma filtering surgery and the date of last examination was 8.55 ± 3.98 years (range, 5-20 years) in this subset. Mean axial length was significantly greater in eyes with pathologic PRD than in those without (28.1 ± 3.3 mm vs. 25.8 ± 2.6 mm; P = 0.01). For axial length ≥ 26 mm, the odds of having a pathologic PRD were 14.4 times more than those with axial length < 26 mm (P < 0.001; 95% confidence interval, 1.7-120.5).
  
  
  CONCLUSIONS
  Prevalence of PRD among eyes with PCG is high. Peripheral retinal screening should be performed in eyes with PCG, especially those with axial lengths ≥ 26 mm.
authors.affiliation: *Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India; and †Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Shikha
authors.initials: S
authors.lastname: Gupta
authors.forename: Varun
authors.initials: V
authors.lastname: Gogia
authors.forename: Cijin
authors.initials: C
authors.lastname: Jose
authors.forename: Bhuvan
authors.initials: B
authors.lastname: Chanana
authors.forename: Ravi
authors.initials: R
authors.lastname: Bypareddy
authors.forename: Kulwant Singh
authors.initials: KS
authors.lastname: Kapoor
authors.forename: Viney
authors.initials: V
authors.lastname: Gupta
mesh_terms: D058452:Axial Length, Eye / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D058450:Endotamponade; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006871:Hydrophthalmos / Q000150:complications* / Q000453:epidemiology; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009887:Ophthalmoscopy; D015995:Prevalence; D012162:Retinal Degeneration / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D012163:Retinal Detachment / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D012189:Retrospective Studies; D014821:Vitrectomy