title: Laparoscopic pancreatic resection.
abstract: Though initially slow to gain acceptance, the minimally invasive approach to pancreatic resection grew during the last decade and pancreatic operations such as the distal pancreatectomy and pancreatic enucleation are frequently performed laparoscopically. More complex operations such as the pancreaticoduodenectomy may also confer benefits with a minimally invasive approach but are less widely utilized. Though most research to date comparing open and laparoscopic pancreatectomy is retrospective, the current data suggest that compared with open, a laparoscopic procedure may afford postoperative benefits such as less blood loss, shorter hospital stay, and fewer wound complications. Regarding oncologic considerations, despite initial concerns, laparoscopic resection appears to be non-inferior to an open procedure in terms of lymph node retrieval, negative margin rates, and long-term survival. New technologies, such as robotics, are also gaining acceptance. Data show that while the laparoscopic approach incurs higher cost in the operating room, the resulting shorter hospital stay appears to be associated with an equivalent or lower overall cost. The minimally invasive approach to pancreatic resection can be safe and appropriate with significant patient benefits and oncologic non-inferiority based on existing data.
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, GA - dkooby@emory.edu.
authors.forename: K N
authors.initials: KN
authors.lastname: Harrell
authors.forename: D A
authors.initials: DA
authors.lastname: Kooby
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery*; D019317:Evidence-Based Medicine; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D015201:Meta-Analysis as Topic; D010180:Pancreatectomy / Q000379:methods; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000379:methods; D012307:Risk Factors; D065287:Robotic Surgical Procedures / Q000379:methods; D016896:Treatment Outcome