title: Quantitative MR Imaging of Brain Tissue and Brain Pathologies.
abstract: Measurement of basic quantitative magnetic resonance (MR) parameters (e.g., relaxation times T1, T2*, T2 or respective rates R (1/T)) corrected for radiofrequency (RF) coil bias yields different conventional and new tissue contrasts as well as volumes for tissue segmentation. This approach also provides quantitative measures of microstructural and functional tissue changes. We herein demonstrate some prospects of quantitative MR imaging in neurological diagnostics and science.
authors.affiliation: Neuroradiologie, Radiologische Klinik des Universitätsklinikums Bonn, Sigmund Freud Strasse 25, 53127, Bonn, Germany. elke.hattingen@ukb.uni-bonn.de.
authors.forename: E
authors.initials: E
authors.lastname: Hattingen
authors.affiliation: Neuroradiologie, Radiologische Klinik des Universitätsklinikums Bonn, Sigmund Freud Strasse 25, 53127, Bonn, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Jurcoane
authors.affiliation: Neuroradiologie, Radiologische Klinik des Universitätsklinikums Bonn, Sigmund Freud Strasse 25, 53127, Bonn, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Nelles
authors.affiliation: Neuroradiologie, Radiologische Klinik des Universitätsklinikums Bonn, Sigmund Freud Strasse 25, 53127, Bonn, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Müller
authors.affiliation: Brain Imaging Center, Universitätsklinikum Frankfurt, Frankfurt/Main, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Nöth
authors.affiliation: Philips Medical Systems, Philips GmbH, Hamburg, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Mädler
authors.affiliation: Neuroradiologie, Radiologische Klinik des Universitätsklinikums Bonn, Sigmund Freud Strasse 25, 53127, Bonn, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Mürtz
authors.affiliation: Brain Imaging Center, Universitätsklinikum Frankfurt, Frankfurt/Main, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Deichmann
authors.affiliation: Radiologische Klinik des Universitätsklinikums Bonn, Sigmund Freud Strasse 25, 53127, Bonn, Germany.
authors.forename: H H
authors.initials: HH
authors.lastname: Schild
mesh_terms: D001921:Brain / Q000473:pathology* / Q000503:physiopathology*; D001927:Brain Diseases / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*
keywords: BOLD; T1-relaxation time; T2-relaxation time; TOLD; qMRI