title: Patients' subjective rating of mental health improvement in a randomised controlled trial.
abstract: We used UK CUtLASS RCT data to establish that patients' rating of mental health improvement (baseline to week 12) correlated significantly with percentage symptom improvement (PANSS). In a regression analysis predictors of the patient's week 12 mental health rating were percentage change in positive symptoms (PANSS), DAI score and the patient's rating of side effects. Patients in an RCT were able to subjectively rate their mental health status, validated by objective improvement on the PANSS.
authors.affiliation: Institute of Brain, Behaviour and Mental Health, The University of Manchester, Manchester, UK. Electronic address: karen.hayhurst@manchester.ac.uk.
authors.forename: Karen P
authors.initials: KP
authors.lastname: Hayhurst
authors.affiliation: Institute of Brain, Behaviour and Mental Health, The University of Manchester, Manchester, UK.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Drake
authors.affiliation: Laureate House Mental Health Unit, Manchester Mental Health & Social Care Trust, Wythenshawe Hospital, Southmoor Road, Manchester, UK.
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Massie
authors.affiliation: Centre for Biostatistics, Institute of Population Health, The University of Manchester, Manchester, UK.
authors.forename: Graham
authors.initials: G
authors.lastname: Dunn
authors.affiliation: Institute of Brain, Behaviour and Mental Health, The University of Manchester, Manchester, UK.
authors.forename: Shôn W
authors.initials: SW
authors.lastname: Lewis
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use*; D059026:Diagnostic Self Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008603:Mental Health / Q000639:trends*; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy*; D016037:Single-Blind Method
chemical_list: D014150:Antipsychotic Agents
keywords: Antipsychotic; Assessment; Schizophrenia