title: Lymphocyte Subpopulations and Cytokine Levels in Experimental Hyperhomocysteinemia.
abstract: Moderate exogenous hyperhomocysteinemia is associated with an increase in lymphocyte count (mainly at the expense of cytotoxic T cells), a 2-fold drop of the immunoregulatory index, and increase in TNF-α, IFN-γ, and IL-17α concentrations in the serum and in mononuclear cells. Homocysteine concentration in the mononuclears remains unchanged.
authors.affiliation: Chita State Medical Academy, Chita, Russia, fefelova.elena@mail.ru.
authors.forename: E V
authors.initials: EV
authors.lastname: Fefelova
authors.forename: P P
authors.initials: PP
authors.lastname: Tereshkov
authors.forename: A A
authors.initials: AA
authors.lastname: Dutov
authors.forename: N N
authors.initials: NN
authors.lastname: Tsybikov
mesh_terms: D000818:Animals; D016207:Cytokines / Q000378:metabolism*; D020138:Hyperhomocysteinemia / Q000276:immunology* / Q000378:metabolism*; D007371:Interferon-gamma / Q000378:metabolism; D020381:Interleukin-17 / Q000378:metabolism; D016131:Lymphocyte Subsets / Q000378:metabolism*; D008297:Male; D051381:Rats; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
chemical_list: D016207:Cytokines; D020381:Interleukin-17; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma