title: Prevalence and factors associated with metabolic syndrome among Tamils aged over 18 years in Jaffna district, Sri Lanka.
abstract: BACKGROUND
  The aim was to determine the prevalence and factors associated with Metabolic Syndrome (MS) among adults aged over 18 years in Jaffna district, Sri Lanka.
  
  
  METHODS
  This study was carried out as a community based cross sectional descriptive study in Jaffna district, Sri Lanka. Multistage stratified cluster sampling technique was employed. Total sample size was 544. An interviewer administrated questionnaire was used to gather data. Waist circumference (WC) and blood pressure (BP) measurements were recorded in standard method. Overnight fasting blood samples were obtained from all subjects. Fasting plasma glucose (FPG), high density lipoprotein (HDL), and triacylglycerols were analyzed by the enzymatic colorimetric assay (Semi Automated analyser Teco Diagnostics TC 3300). Modified National Cholesterol Education Program's Adult Treatment Panel III (NCEP ATP III) criterion was used to define the MS.
  
  
  RESULTS
  Sample response rate was 95.3 %. Of them, 43.8 % (n = 224) was male. Prevalence of central obesity (WC for male ≥102 cm, female ≥88 cm) was 16.2 %. Prevalence of raised FPG (≥100 mg/dL), hypertriacylglycerolaemia (≥150 mg/dl), low level of HDL cholesterol (<40 mg/dL in males, <50 mg/dL in females) and raised BP (systolic BP ≥130 or diastolic BP ≥85 mmHg) were 23.9, 25, 79.3 and 36.6 % respectively. Prevalence of MS was 24.1 % (n = 123, 95 % CI: 20.4-28) and it was 26.8 and 21.9 % among males and females respectively. Participants living in urban area had higher prevalence of MS when compared with participants living in rural area (P = 0.015). Older age (P < 0.001) and smoking (P = 0.005) were risk factor for development of MS. Prevalence of MS among the participants with sedentary and active lifestyle was 29.9 and 23.7 % respectively.
  
  
  CONCLUSIONS
  One out of four had MS. Old age, urban living and smoking carried higher risk for developing MS in Jaffna community.
authors.affiliation: Department of Biochemistry, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.
authors.forename: Sivarathy
authors.identifier: 0000-0003-4227-8863
authors.initials: S
authors.lastname: Amarasinghe
authors.affiliation: Department of Biochemistry, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.
authors.forename: Sandrasegarampillai
authors.initials: S
authors.lastname: Balakumar
authors.affiliation: Department of Biochemistry, Faculty of Medicine, University of Jaffna, Jaffna, Sri Lanka.
authors.forename: Vasanthy
authors.initials: V
authors.lastname: Arasaratnam
keywords: Central obesity; Fasting plasma glucose; High density lipoprotein; Hypertriacylglycerolaemia; Metabolic syndrome