title: In the land of giants: the legacy of José Dantas de Souza Leite.
abstract: The authors describe the extraordinary contribution to science made by José Dantas de Souza Leite, who graduated from the Bahia School of Medicine and trained in Prof. Charcot's Neurology Service under the supervision of Charcot's most able pupil, Dr. Pierre Marie. Souza Leite presented his doctoral thesis on acromegaly, in Paris in 1890, and in the following year both him and Pierre Marie published a book on the subject, "Essays on Acromegaly". This exceptional work established Souza Leite internationally as an important researcher, and the first Brazilian physician to contribute to the development of neuroendocrinology in an innovative way.
authors.affiliation: Departamento de Clínica Médica, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Hélio A G
authors.initials: HA
authors.lastname: Teive
authors.affiliation: Departamento de Clínica Médica, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Plínio M
authors.initials: PM
authors.lastname: Lima
authors.affiliation: Departamento de Clínica Médica, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Francisco M B
authors.initials: FM
authors.lastname: Germiniani
authors.affiliation: Departamento de Clínica Médica, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: César L
authors.initials: CL
authors.lastname: Boguszewski
mesh_terms: D000172:Acromegaly / Q000266:history*; D001938:Brazil; D049672:History, 19th Century; D049673:History, 20th Century; D008488:Medical Illustration; D009452:Neuroendocrinology / Q000266:history; D009462:Neurology / Q000266:history*; D010297:Paris