title: Obesity-related differences in neuromuscular fatigue in adolescent girls.
abstract: OBJECTIVE
  The aim of this study was to investigate the effect of obesity on neuromuscular fatigue in adolescent girls.
  
  
  METHODS
  Twelve lean (13.6 ± 0.8 years) and 12 obese (13.9 ± 0.9 years) girls repeated 5-s maximal voluntary contractions (MVC) of the knee extensors until the generated torque reached 55 % of its initial value. Magnetic stimulations were delivered to the femoral nerve every five MVCs to follow the course of voluntary activation (VA) and potentiated twitch torque (Qtwpot).
  
  
  RESULTS
  Torque reached 55 % of its initial value after 52.6 ± 20.4 and 74.9 ± 22.8 repetitions in obese and lean girls, respectively (p < 0.01). Furthermore, the decline of VA was smaller in obese girls (p < 0.001). In contrast, Qtwpot decreased to a greater extent in obese girls (p < 0.05).
  
  
  CONCLUSIONS
  Obese girls fatigue faster than their lean counterparts. The peripheral factors mainly account for fatigue in obese girls, whereas central factors are mainly involved in lean girls.
authors.affiliation: EA 3533, Laboratory of Metabolic Adaptations During Exercise in Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, Blaise Pascal University, BP 10448, 63000, Clermont-Ferrand, France.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Garcia-Vicencio
authors.affiliation: EA 3533, Laboratory of Metabolic Adaptations During Exercise in Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, Blaise Pascal University, BP 10448, 63000, Clermont-Ferrand, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Martin
authors.affiliation: EA 3533, Laboratory of Metabolic Adaptations During Exercise in Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, Blaise Pascal University, BP 10448, 63000, Clermont-Ferrand, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Kluka
authors.affiliation: Clermont University Hospital, Clermont-Ferrand, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Cardenoux
authors.affiliation: Clermont University Hospital, Clermont-Ferrand, France.
authors.forename: Anne-Gaëlle
authors.initials: AG
authors.lastname: Jegu
authors.affiliation: MECSS Tza Nou, La Bourboule, France.
authors.forename: Anne-Véronique
authors.initials: AV
authors.lastname: Fourot
authors.affiliation: Clermont University Hospital, Clermont-Ferrand, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Coudeyre
authors.affiliation: EA 3533, Laboratory of Metabolic Adaptations During Exercise in Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, Blaise Pascal University, BP 10448, 63000, Clermont-Ferrand, France. sebastien.ratel@univ-bpclermont.fr.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Ratel
mesh_terms: D000293:Adolescent; D002648:Child; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D005267:Femoral Nerve / Q000503:physiopathology; D006801:Humans; D007537:Isometric Contraction / Q000502:physiology*; D018763:Muscle Fatigue / Q000502:physiology*; D053580:Muscle Strength / Q000502:physiology*; D009765:Obesity / Q000503:physiopathology*; D019415:Torque
keywords: Adolescence; Central fatigue; Electromyography; Peripheral fatigue; Peripheral magnetic stimulation