title: Atropo- and Diastereoselective Construction of Tetracyclic Biphenylazepinium Salts Derived from Aminoalcohols: Use as Catalysts in Enantioselective Asymmetric Epoxidation.
abstract: A range of new biphenylazepinium salt organocatalysts effective for asymmetric epoxidation has been developed incorporating an additional substituted oxazolidine ring, and providing improved enantiocontrol in alkene epoxidation over the parent structure. Starting from enantiomerically pure aminoalcohols, tetracyclic iminium salts were obtained as single diastereoisomers through an atroposelective oxazolidine formation.
authors.affiliation: †School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, U.K.
authors.forename: Philip C
authors.initials: PC
authors.lastname: Bulman Page
authors.affiliation: †School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, U.K.
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Pearce
authors.affiliation: †School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, U.K.
authors.forename: Yohan
authors.initials: Y
authors.lastname: Chan
authors.affiliation: ‡Chemistry Department, Loughborough University, Loughborough, Leicestershire LE11 3TU, U.K.
authors.forename: Phillip
authors.initials: P
authors.lastname: Parker
authors.affiliation: ‡Chemistry Department, Loughborough University, Loughborough, Leicestershire LE11 3TU, U.K.
authors.forename: Benjamin R
authors.initials: BR
authors.lastname: Buckley
authors.affiliation: §Department of Chemistry, University of Patras, 26504 Patras, Greece.
authors.forename: Gerasimos A
authors.initials: GA
authors.lastname: Rassias
authors.affiliation: ‡Chemistry Department, Loughborough University, Loughborough, Leicestershire LE11 3TU, U.K.
authors.forename: Mark R J
authors.initials: MR
authors.lastname: Elsegood