title: [Effects of continuous blood purification on extravascular lung water and respiratory function in patients with extrapulmonary acute respiratory distress syndrome].
abstract: OBJECTIVE
  To assess the effects of continuous blood purification (CBP) on extravascular lung water and respiratory function in patients with extrapulmonary acute respiratory distress syndrome (ARDSexp).
  
  
  METHODS
  The data of 31 patients with ARDSexp admitted in our department were retrospectively analyzed.Sixteen of the patients received CBP, and the other 15 patients did not (control group). The level of extravascular lung water index (EVLWI), pulmonary vascular permeability index (PVPI), and respiratory function were measured before and after CPB.
  
  
  RESULTS
  The mortality rate was significantly lower in CBP group than in the control group (12.5% vs 33.3%, P<0.05). The patients in CPB group showed markedly earlier and significantly greater improvements in EVLWI, PVPI, PaO2/FiO, and respiratory function than the control patients (P<0.05).
  
  
  CONCLUSIONS
  CBP can reduce EVLWI and PVPI, improve pulmonary compliance and oxygenation, and reduce mortality rate in patients with ARDSexp.
authors.affiliation: Department of Critical Care Medicine, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China.E-mail: ninglzb@163.com.
authors.forename: Zhibo
authors.initials: Z
authors.lastname: Li
authors.forename: Deliang
authors.initials: D
authors.lastname: Wen
authors.forename: Weijiang
authors.initials: W
authors.lastname: Liu
authors.forename: Xuming
authors.initials: X
authors.lastname: Xiong
mesh_terms: D002199:Capillary Permeability; D015633:Extravascular Lung Water; D006440:Hemofiltration; D006801:Humans; D008168:Lung; D008991:Monitoring, Physiologic; D012119:Respiration; D012128:Respiratory Distress Syndrome; D012189:Retrospective Studies