title: Pseudoepitheliomatous Hyperplasia: Relevance in Oral Pathology.
abstract: Pseudoepitheliomatous hyperplasia (PEH), a neglected entity by oral pathologist possesses utmost importance in the field of research. Of all the investigative challenges, PEH, a reactive epithelial proliferation is seen secondary to lesions with infectious, inflammatory, reactive, and degenerative origin. Small sized samples, incomplete excision, improper orientation, and dense inflammatory changes render diagnostic confront to the oral pathologist in exclusion of frankly invasive malignant lesions like squamous cell carcinoma from lesions exhibiting PEH. The diagnosis can occasionally be difficult as they mimic other lesions also, on clinic-pathological assessment. Thus, this article gives an insight regarding the various concepts of etiopathogenesis, histopathology, differential diagnosis, and malignant potential of PEH. A combined effort of a clinician and pathologist benefits every patient to rule out malignancy and render appropriate treatment as the only local conservative approach is essential to remove PEH associated lesions.
authors.affiliation: Professor, Department of Oral Pathology, Madha Dental College and Hospital, Kundrathur, Chennai, Tamil Nadu, India.
authors.forename: R
authors.initials: R
authors.lastname: Sarangarajan
authors.affiliation: Lecturer, Department of Oral Pathology and Microbiology, Faculty of Dentistry, Asian Institute of Medicine Science and Technology University, Malaysia.
authors.forename: V K Vaishnavi
authors.initials: VK
authors.lastname: Vedam
authors.affiliation: Lecturer, Department of Pedodontics, Faculty of Dentistry, Asian Institute of Medicine Science and Technology, University, Malaysia.
authors.forename: G
authors.initials: G
authors.lastname: Sivadas
authors.affiliation: Senior Lecturer, Department of Prosthodontics, Rajah Muthiah Dental College and Hospital, Chidambaram, Tamil Nadu, India.
authors.forename: R
authors.initials: R
authors.lastname: Krishnaraj
authors.affiliation: General Dental Practitioner, Sai Raghav Dental Clinic, Chennai, Tamil Nadu, India.
authors.forename: Anuradha
authors.initials: A
authors.lastname: Sarangarajan
authors.affiliation: Reader, Department of Oral Pathology, Madha Dental College & Hospital, Kundrathur, Chennai, Tamil Nadu, India.
authors.forename: K T
authors.initials: KT
authors.lastname: Shanmugam
keywords: Keratoacanthoma; malignant melanoma; pseudoepithe liomatous hyperplasia; squamous cell carcinoma; verrucous carcinoma