title: Transcatheter aortic valve-in-valve implantation for severe bioprosthetic stenosis after Bentall operation using a homograft in a patient with Behçet's disease.
abstract: A 43-year-old man presented with severe aortic stenosis. Eight years previously, he had undergone primary surgical aortic valve replacement (AVR) for severe aortic regurgitation, but one year later developed cardiac arrest and complete atrioventricular block as a result of non-bacterial thrombotic endocarditis with severe valvular dehiscence. Following the diagnosis of prosthetic valve failure caused by Behçet's disease, the patient underwent a Bentall operation using 23 mm aortic homograft with permanent pacemaker implantation and coronary artery bypass grafting. Subsequently, he was stable with steroid administration and azathioprine for seven years after the second operation, but recently suffered from severe dyspnea and chest pain. Echocardiography revealed the development of severe aortic stenosis. A preprocedural evaluation demonstrated a porcelain aorta with severe calcification in the previous homograft valve on computed tomography, and critical stenosis at the ostium of the left circumflex artery on coronary angiography. After percutaneous coronary intervention for the ostium of the left circumflex artery, a transcatheter AVR was successfully performed using a 26 mm Edwards SAPIEN XT valve. The patient recovered without any complications after the procedure. This is the first report of a successful transcatheter aortic valve-in valve implantation for severe homograft aortic stenosis after a Bentall operation, using a homograft, in a patient with Behçet's disease.
authors.forename: Hyung Joon
authors.initials: HJ
authors.lastname: Joo
authors.forename: Soon Jun
authors.initials: SJ
authors.lastname: Hong
authors.forename: Cheol Woong
authors.initials: CW
authors.lastname: Yu
mesh_terms: D000328:Adult; D064591:Allografts; D001024:Aortic Valve Stenosis / Q000601:surgery*; D001528:Behcet Syndrome / Q000601:surgery*; D001705:Bioprosthesis; D003251:Constriction, Pathologic; D017548:Echocardiography, Transesophageal; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male