title: A high-performance imaging probe with NIR luminescence and synergistically enhanced T1-T2 relaxivity for in vivo hepatic tumor targeting and multimodal imaging.
abstract: A high-performance imaging probe with NIR luminescence and synergistically enhanced T1-T2 relaxivity was synthesized. This nanoprobe exhibits a relatively high tumor-targeting efficacy and enables NIR optical and T1-/T2-weighted MR imaging of hepatic tumor cells in vivo.
authors.affiliation: Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry Lanzhou University Gansu, Lanzhou University, Lanzhou, 730000, P. R. China. wangbd@lzu.edu.cn.
authors.forename: Jian
authors.initials: J
authors.lastname: Liu
authors.forename: Zhengzheng
authors.initials: Z
authors.lastname: Li
authors.forename: Xiangliang
authors.initials: X
authors.lastname: Yang
authors.forename: Weisheng
authors.initials: W
authors.lastname: Liu
authors.forename: Baodui
authors.initials: B
authors.lastname: Wang
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Zhu
authors.forename: Ketao
authors.initials: K
authors.lastname: Mu
authors.forename: Wenzhen
authors.initials: W
authors.lastname: Zhu
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D003287:Contrast Media / Q000737:chemistry*; D056831:Coordination Complexes / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D005682:Gadolinium / Q000737:chemistry; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D051379:Mice; D008819:Mice, Nude; D064847:Multimodal Imaging; D049329:Nanostructures / Q000737:chemistry; D011859:Radiography; D019265:Spectroscopy, Near-Infrared; D014183:Transplantation, Heterologous
chemical_list: D003287:Contrast Media; D056831:Coordination Complexes; D005456:Fluorescent Dyes; D005682:Gadolinium