title: Use of Neonatal Fostering To Remove Helicobacter spp. from Deer Mice (Peromyscus maniculatus).
abstract: Helicobacter species can be found in a wide variety of animals and remain common contaminants of laboratory rodents. Fostering of neonatal pups has been used to eliminate Helicobacter spp. from various laboratory rodents, including laboratory mice and gerbils. Deer mice (Peromyscus maniculatus) from a captive colony enzootic for at least one Helicobacter species were mated, and the pups produced were fostered on laboratory mice 24 h after birth. After 2 rounds of fostering, both foster dams and pups were free of Helicobacter spp. as determined by fecal PCR analysis. Removal of Helicobacter infection through neonatal fostering has not been described previously for Peromyscus maniculatus.
authors.affiliation: Office of Animal Resources, Harvard University Faculty of Arts and Sciences, Cambridge, Massachusetts, USA; Charles River Laboratories, Wilmington, Massachusetts, USA. pritchettcorning@fas.harvard.edu.
authors.forename: Kathleen R
authors.initials: KR
authors.lastname: Pritchett-Corning
authors.affiliation: Division of Reproductive Biology, Department of Obstetrics and Gynecology, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Harry E
authors.initials: HE
authors.lastname: Peery
authors.affiliation: Peromyscus Genetic Stock Center, Office of Research, University of South Carolina, Columbia, South Carolina, USA.
authors.forename: Janet P
authors.initials: JP
authors.lastname: Crossland
authors.affiliation: Biological Research Facility, Chalk River Laboratories, Canadian Nuclear Laboratories, Chalk River, Ontario, Canada.
authors.forename: Heather M
authors.initials: HM
authors.lastname: Wyatt
authors.affiliation: Environmental Technologies Branch, Chalk River Laboratories, Canadian Nuclear Laboratories, Chalk River, Ontario, Canada.
authors.forename: Marilyne
authors.initials: M
authors.lastname: Stuart
authors.affiliation: Department of Medical Physics and Applied Radiation Sciences, Faculty of Science, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Carmel E
authors.initials: CE
authors.lastname: Mothersill
mesh_terms: D000827:Animal Welfare; D000818:Animals; D000830:Animals, Laboratory; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D005243:Feces / Q000382:microbiology; D005260:Female; D016998:Helicobacter / Q000145:classification / Q000502:physiology*; D016481:Helicobacter Infections / Q000517:prevention & control / Q000662:veterinary*; D008297:Male; D010542:Peromyscus; D016133:Polymerase Chain Reaction; D012376:Rodent Diseases / Q000517:prevention & control*
chemical_list: D004269:DNA, Bacterial