title: Malignant salivary gland tumours of the head and neck region: a single institutions review.
abstract: BACKGROUND
  Malignant salivary gland tumours (MSGTs) comprise about 3% of all head and neck cancers; they demonstrate an unpredictable clinical course. The purpose of this study is to review MSGTs seen at a tertiary Health centre, and compare findings with those of previous studies.
  
  
  METHODS
  The records of the Department of Oral Pathology and the Department of Pathology, University College Hospital Ibadan were reviewed over a 19 year period and lesions diagnosed as MSGTs according to 2005 WHO histological classification were analysed for age, gender and site using SPSS for Windows (version 20.0; SPSS Inc. Chicago, IL).
  
  
  RESULTS
  MSGTs were more common in males (55.2%) than females (44.8%). The mean age of was 47.9 (±17.0) years and peak age was the fifth decade. The parotid gland was the commonest site with 62 (28.1%) cases. The palate was the commonest intraoral site with 61(27.6%). The nose with 19 (8.6%) was the commonest minor extra-oral site.
  
  
  CONCLUSIONS
  The findings were essentially similar to reports from Europe and America. Adenoid Cystic Carcinoma was the most common MSGT in this series. A high proportion of salivary gland tumours in sublingual gland were malignant. The reason(s) for high proportion of MSGTs in sublingual glands requires further investigation.
authors.affiliation: Department of Oral Pathology, College of Medicine, University of Ibadan, Nigeria.
authors.forename: Ahmed Oluwatoyin
authors.initials: AO
authors.lastname: Lawal
authors.affiliation: Department of Oral Pathology, College of Medicine, University of Ibadan, Nigeria.
authors.forename: Akinyele Olumuyiwa
authors.initials: AO
authors.lastname: Adisa
authors.affiliation: Department of Oral Pathology, College of Medicine, University of Ibadan, Nigeria.
authors.forename: Bamidele
authors.initials: B
authors.lastname: Kolude
authors.affiliation: Department of Oral Pathology, College of Medicine, University of Ibadan, Nigeria.
authors.forename: Bukola Folasade
authors.initials: BF
authors.lastname: Adeyemi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003528:Carcinoma, Adenoid Cystic / Q000453:epidemiology* / Q000401:mortality; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D012468:Salivary Gland Neoplasms / Q000453:epidemiology* / Q000401:mortality; D012470:Salivary Glands, Minor / Q000473:pathology; D016019:Survival Analysis; D055815:Young Adult
keywords: Malignant salivary gland tumour; adenoid cystic carcinoma; mucoepidermoid carcinoma; polymorphous low-grade adenocarcinoma