title: Spectral Imaging Technology-Based Evaluation of Radiation Treatment Planning to Remove Contrast Agent Artifacts.
abstract: This study employs dual-source computed tomography single-spectrum imaging to evaluate the effects of contrast agent artifact removal and the computational accuracy of radiotherapy treatment planning improvement.
  
  
  
  The phantom, including the contrast agent, was used in all experiments. The amounts of iodine in the contrast agent were 30, 15, 7.5, and 0.75 g/100 mL. Two images with different energy values were scanned and captured using dual-source computed tomography (80 and 140 kV). To obtain a fused image, 2 groups of images were processed using single-energy spectrum imaging technology. The Pinnacle planning system was used to measure the computed tomography values of the contrast agent and the surrounding phantom tissue. The difference between radiotherapy treatment planning based on 80 kV, 140 kV, and energy spectrum image was analyzed.
  
  
  
  For the image with high iodine concentration, the quality of the energy spectrum-fused image was the highest, followed by that of the 140-kV image. That of the 80-kV image was the worst. The difference in the radiotherapy treatment results among the 3 models was significant. When the concentration of iodine was 30 g/100 mL and the distance from the contrast agent at the dose measurement point was 1 cm, the deviation values (P) were 5.95% and 2.20% when image treatment planning was based on 80 and 140 kV, respectively. When the concentration of iodine was 15 g/100 mL, deviation values (P) were -2.64% and -1.69%.
  
  
  
  Dual-source computed tomography single-energy spectral imaging technology can remove contrast agent artifacts to improve the calculated dose accuracy in radiotherapy treatment planning.
authors.affiliation: Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Yi-Qun
authors.affiliation: Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, China.
authors.forename: Liu
authors.initials: L
authors.lastname: Wei
authors.affiliation: Second People's Hospital of Changzhou, Nanjing Medical University, Changzhou, China nxy2000@aliyun.com.
authors.forename: Ni
authors.initials: N
authors.lastname: Xin-Ye
mesh_terms: D016477:Artifacts; D003287:Contrast Media; D006801:Humans; D007455:Iodine; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy; D019047:Phantoms, Imaging; D011880:Radiotherapy Planning, Computer-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media; D007455:Iodine
keywords: CT value; computed tomography; contrast agent; dose; energy spectral imaging technology; radiotherapy