title: [DRESS syndrome: Report of nine cases].
abstract: BACKGROUND
  DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs. It is characterized by a polymorphic disseminated eruption with fever and multiple organ dysfunction.
  
  
  OBJECTIVE
  To report the etiology, characteristics, treatment, prognosis, and follow up of patients with DRESS Syndrome admitted to a clinical hospital.
  
  
  METHODS
  Review of medical records of patients admitted for drug reactions, selecting those patients complying with clinical criteria for DRESS Syndrome. Drugs used during three months prior to the onset of symptoms were evaluated as possible causes of the disease.
  
  
  RESULTS
  Nine patients aged 16 to 68 years (six males) complied with the clinical criteria for the disease. The causative medications were carbamazepine in three patients, phenytoin in three, antituberculous drugs in two and amoxicillin in one. All were treated with systemic steroids with a complete clinical resolution.
  
  
  CONCLUSIONS
  DRESS syndrome is usually underdiagnosed and has a good response to systemic steroids.
authors.forename: Jorge
authors.initials: J
authors.lastname: Ocampo-Garza
authors.forename: Sonia Sofía
authors.initials: SS
authors.lastname: Ocampo-Garza
authors.forename: José Darío
authors.initials: JD
authors.lastname: Martínez-Villarreal
authors.forename: Laura Elena
authors.initials: LE
authors.lastname: Barbosa-Moreno
authors.forename: Guillermo Antonio
authors.initials: GA
authors.lastname: Guerrero-González
authors.forename: Jorge
authors.initials: J
authors.lastname: Ocampo-Candiani
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002220:Carbamazepine / Q000009:adverse effects; D003907:Dexamethasone / Q000627:therapeutic use*; D063926:Drug Hypersensitivity Syndrome / Q000188:drug therapy* / Q000209:etiology; D004802:Eosinophilia / Q000150:complications; D005076:Exanthema / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000009:adverse effects; D011241:Prednisone / Q000627:therapeutic use*; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D002220:Carbamazepine; D010672:Phenytoin; D003907:Dexamethasone; D011241:Prednisone