title: Atmospheric Dispersal of Bioactive Streptomyces albidoflavus Strains Among Terrestrial and Marine Environments.
abstract: Members of the Streptomyces albidoflavus clade, identified by 16S rRNA sequencing and phylogenetic analyses, are widespread among predominant terrestrial lichens (Flavoparmelia caperata and Xanthoria parietina) and diverse intertidal and subtidal marine macroalgae, brown red and green (Phylum Heterokontophyta, Rhodophyta, and Chlorophyta) from the Cantabrian Cornice. In addition to these terrestrial and coastal temperate habitats, similar strains were also found to colonize deep-sea ecosystems and were isolated mainly from gorgonian and solitary corals and other invertebrates (Phylum Cnidaria, Annelida, Echinodermata, Arthropoda, and Porifera) living up to 4700-m depth and at a temperature of 2-4 °C in the submarine Avilés Canyon. Similar strains have been also repeatedly isolated from atmospheric precipitations (rain drops, snow, and hailstone) collected in the same area throughout a year observation time. These ubiquitous strains were found to be halotolerant, psychrotolerant, and barotolerant. Bioactive compounds with diverse antibiotic and cytotoxic activities produced by these strains were identified by high-performance liquid chromatography (HPLC) and database comparison. These include antibacterials (paulomycins A and B), antifungals (maltophilins), antifungals displaying also cytotoxic activities (antimycins and 6-epialteramides), and the antitumor compound fredericamycin. A hypothetical dispersion model is here proposed to explain the biogeographical distribution of S. albidoflavus strains in terrestrial, marine, and atmospheric environments.
authors.affiliation: Departamento de Biología Funcional, Área de Microbiología, e Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, 33006, Oviedo, Spain.
authors.forename: Aida
authors.initials: A
authors.lastname: Sarmiento-Vizcaíno
authors.affiliation: Departamento de Biología Funcional, Área de Microbiología, e Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, 33006, Oviedo, Spain.
authors.forename: Alfredo F
authors.initials: AF
authors.lastname: Braña
authors.affiliation: Departamento de Biología Funcional, Área de Microbiología, e Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, 33006, Oviedo, Spain.
authors.forename: Verónica
authors.initials: V
authors.lastname: González
authors.affiliation: Departamento de Biología de Organismos y Sistemas, Área de Botánica, Universidad de Oviedo, Oviedo, Spain.
authors.forename: Herminio
authors.initials: H
authors.lastname: Nava
authors.affiliation: Departamento de Biología de Organismos y Sistemas, Área de Ecología, Universidad de Oviedo, Oviedo, Spain.
authors.forename: Axayacatl
authors.initials: A
authors.lastname: Molina
authors.affiliation: Centro de Experimentación Pesquera del Principado de Asturias, Gijón, Spain.
authors.forename: Eva
authors.initials: E
authors.lastname: Llera
authors.affiliation: Mikrobiologisches Institut, Universität Tübingen, D-72076, Tübingen, Germany.
authors.forename: Hans-Peter
authors.initials: HP
authors.lastname: Fiedler
authors.affiliation: Departamento de Biología de Organismos y Sistemas, Área de Ecología, Universidad de Oviedo, Oviedo, Spain.
authors.forename: José M
authors.initials: JM
authors.lastname: Rico
authors.affiliation: Centro de Experimentación Pesquera del Principado de Asturias, Gijón, Spain.
authors.forename: Lucía
authors.initials: L
authors.lastname: García-Flórez
authors.affiliation: Departamento de Biología de Organismos y Sistemas, Área de Ecología, Universidad de Oviedo, Oviedo, Spain.
authors.forename: José L
authors.initials: JL
authors.lastname: Acuña
authors.affiliation: Departamento de Ingeniería Química y Tecnología del Medio Ambiente, Área de Ingeniería Química, Universidad de Oviedo, Oviedo, Spain.
authors.forename: Luis A
authors.initials: LA
authors.lastname: García
authors.affiliation: Departamento de Biología Funcional, Área de Microbiología, e Instituto Universitario de Oncología del Principado de Asturias, Universidad de Oviedo, 33006, Oviedo, Spain. gbb@uniovi.es.
authors.forename: Gloria
authors.initials: G
authors.lastname: Blanco
mesh_terms: D000818:Animals; D001685:Biological Factors / Q000737:chemistry / Q000378:metabolism; D007448:Invertebrates / Q000145:classification / Q000382:microbiology*; D008011:Lichens / Q000382:microbiology; D012623:Seawater / Q000382:microbiology*; D013302:Streptomyces / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism
chemical_list: D001685:Biological Factors
keywords: Actinobacteria; Antibiotic; Antitumor; Avilés Canyon; Clouds; Corals; Lichens; Seaweeds