title: C-F bond substitution via aziridinium ion intermediates.
abstract: Aliphatic 1,2-aminofluorides undergo extremely fast substitution reactions under the influence of lanthanum tris(hexamethyldisilazide). The substitution proceeds via an in situ generated aziridinium ion intermediate, which subsequently undergoes ring opening by addition of a nucleophile, yielding various β-substituted amines.
authors.affiliation: Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, SE-412 96, Gothenburg, Sweden. hilmer@chem.gu.se.
authors.forename: A M
authors.initials: AM
authors.lastname: Träff
authors.forename: M
authors.initials: M
authors.lastname: Janjetovic
authors.forename: G
authors.initials: G
authors.lastname: Hilmersson