title: Safety Assessment of Ethanolamides as Used in Cosmetics.
abstract: The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) rereviewed the safety of 28 ethanolamides and found them safe in the present practices of use and concentration when they are formulated to be nonirritating, and that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed. Most of the ethanolamides are reported to function in cosmetics as hair-conditioning agents, skin-conditioning agents, and surfactant-foam boosters. The Panel reviewed available animal and clinical data, as well as information from previous CIR reports.
authors.affiliation: Cosmetic Ingredient Review Senior Scientific Analyst/Writer, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Monice M
authors.initials: MM
authors.lastname: Fiume
authors.affiliation: Cosmetic Ingredient Review Chemist, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Bart A
authors.initials: BA
authors.lastname: Heldreth
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Wilma F
authors.initials: WF
authors.lastname: Bergfeld
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Donald V
authors.initials: DV
authors.lastname: Belsito
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Ronald A
authors.initials: RA
authors.lastname: Hill
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Curtis D
authors.initials: CD
authors.lastname: Klaassen
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Liebler
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: James G
authors.initials: JG
authors.lastname: Marks
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Ronald C
authors.initials: RC
authors.lastname: Shank
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Slaga
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: Paul W
authors.initials: PW
authors.lastname: Snyder
authors.affiliation: Former Director, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: F Alan
authors.initials: FA
authors.lastname: Andersen
mesh_terms: D000577:Amides / Q000737:chemistry / Q000633:toxicity*; D000818:Animals; D015197:Carcinogenicity Tests; D003257:Consumer Product Safety; D003358:Cosmetics / Q000633:toxicity*; D004983:Ethanolamines / Q000633:toxicity; D007509:Irritants / Q000633:toxicity; D012098:Reproduction / Q000187:drug effects
chemical_list: D000577:Amides; D003358:Cosmetics; D004983:Ethanolamines; D007509:Irritants
keywords: cosmetics; ethanolamides; safety