title: Inhibition of hardy kiwifruit (Actinidia aruguta) ripening by 1-methylcyclopropene during cold storage and anticancer properties of the fruit extract.
abstract: Hardy kiwifruits (Actinidia arguta) were treated with 20 μl/l 1-methylcyclopropene (1-MCP) for 16 h at 10 °C and subsequently stored at 1 ± 0.5 °C. Anticancer properties of the fruit extracts were tested against five different human cancer cells. The hardy kiwifruits, without 1-MCP treatment, showed increases in both respiration and ethylene production rates during fruit storage. The 1-MCP treatment remarkably inhibited fruit ripening by reducing respiration and ethylene production. Fruits with the 1-MCP treatment could be stored for up to 5 weeks by maintaining higher fruit firmness, ascorbic acid and total phenolic contents compared to the control. The hardy kiwifruit extracts showed anti-proliferative effects to Hep3B and HeLa cells but not to HT29, HepG2 and LoVo cells. These results suggest that the application of 1-MCP at harvest effectively delayed the ripening process of the fruits, and the fruit extract had beneficial effects for the prevention of human cancer growth.
authors.affiliation: Department of Plant Science, Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
authors.forename: Sooyeon
authors.initials: S
authors.lastname: Lim
authors.affiliation: Department of Plant Science, Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
authors.forename: Seung Hyun
authors.initials: SH
authors.lastname: Han
authors.affiliation: Department of NanoBiomedical Science, DanKook University Graduate School, Cheonan 330-714, Republic of Korea.
authors.forename: Jeongyun
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Plant Science, Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
authors.forename: Han Jun
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of Plant Science, Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea.
authors.forename: Jeong Gu
authors.initials: JG
authors.lastname: Lee
authors.affiliation: Department of Plant Science, Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea. Electronic address: ejinlee3@snu.ac.kr.
authors.forename: Eun Jin
authors.initials: EJ
authors.lastname: Lee
mesh_terms: D029042:Actinidia / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry*; D003080:Cold Temperature; D003521:Cyclopropanes / Q000737:chemistry*; D061353:Food Storage / Q000379:methods*; D005638:Fruit / Q000737:chemistry*; D010636:Phenols / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D003521:Cyclopropanes; D010636:Phenols; C412563:1-methylcyclopropene
keywords: Anticancer effect; Baby kiwi; Ethylene action inhibitor; Fruit quality; Postharvest