title: A single fluorophore to address multiple logic gates.
abstract: Logic gates with different radixes have been constructed using a biologically active molecule, 2-(4'-N,N-dimethylaminophenyl)imidazo[4,5-b]pyridine (DMAPIP-b). Taking advantage of the multiple binding sites of the fluorophore, a series of different molecular logic gates are developed using fluorescence intensities at different wavelengths. The high emission of the molecule is drastically quenched in the presence of Fe(3+). It is regained by the addition of an equivalent amount of F(-). The fluorescence On-Off nature has been used to construct molecular full subtractor and molecular keypad lock system with Boolean logic. A ternary system is generated by considering three defined fluorescence intensities at particular wavelengths. The smooth dependency of emission intensities with analyte concentration is utilized to construct an infinite-valued fuzzy logic system. The fuzzy logic system is further coupled with a neuro-adaptation method to predict more accurately the dependency of molecular intensity on external inputs.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India. gkrishna@iitg.ernet.in.
authors.forename: Saugata
authors.initials: S
authors.lastname: Sahu
authors.forename: Timir Baran
authors.initials: TB
authors.lastname: Sil
authors.forename: Minati
authors.initials: M
authors.lastname: Das
authors.forename: G
authors.initials: G
authors.lastname: Krishnamoorthy
mesh_terms: D005290:Ferric Compounds / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D005459:Fluorides / Q000737:chemistry; D011725:Pyridines / Q000737:chemistry
chemical_list: D005290:Ferric Compounds; D005456:Fluorescent Dyes; D011725:Pyridines; C023666:pyridine; D005459:Fluorides