title: Preventing Diabetic Ketoacidosis.
abstract: Diabetic ketoacidosis (DKA) is a major cause of morbidity and mortality in children with type 1 diabetes mellitus (T1DM). This article examines the factors associated with DKA in children with T1DM, both at first presentation and in recurrent cases. The challenge for future research is to find effective ways to improve primary care physician and general community awareness of T1DM to reduce DKA at presentation and develop practical, cost-effective programs to reduce recurrent DKA.
authors.affiliation: Paediatric Endocrinology Service, Starship Children's Hospital, Auckland District Health Board, 2 Park Road, Auckland, 1023, New Zealand; Liggins Institute, University of Auckland, 85 Park Road, Auckland, 1023, New Zealand. Electronic address: CraigJ@adhb.govt.nz.
authors.forename: Craig A
authors.initials: CA
authors.lastname: Jefferies
authors.affiliation: Department of Paediatrics, Montreal Children's Hospital, McGill University, 2300 Tupper Street, H3H 1P3, Montreal, Canada.
authors.forename: Meranda
authors.initials: M
authors.lastname: Nakhla
authors.affiliation: Liggins Institute, University of Auckland, 85 Park Road, Auckland, 1023, New Zealand.
authors.forename: José G B
authors.initials: JG
authors.lastname: Derraik
authors.affiliation: Paediatric Endocrinology Service, Starship Children's Hospital, Auckland District Health Board, 2 Park Road, Auckland, 1023, New Zealand; Department of Physiology, University of Auckland, 85 Park Road, Auckland, 1023, New Zealand.
authors.forename: Alistair J
authors.initials: AJ
authors.lastname: Gunn
authors.affiliation: Department of Pediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, M5G 1X8, Toronto, Canada.
authors.forename: Denis
authors.initials: D
authors.lastname: Daneman
authors.affiliation: Paediatric Endocrinology Service, Starship Children's Hospital, Auckland District Health Board, 2 Park Road, Auckland, 1023, New Zealand; Liggins Institute, University of Auckland, 85 Park Road, Auckland, 1023, New Zealand.
authors.forename: Wayne S
authors.initials: WS
authors.lastname: Cutfield
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D016883:Diabetic Ketoacidosis / Q000150:complications / Q000209:etiology* / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012307:Risk Factors; D012737:Sex Factors
keywords: Diabetic ketoacidosis; Education; Girls; Noncompliance; Prevention; Recurrent; Type 1 diabetes mellitus