title: Curcumin Resource Database.
abstract: Curcumin is one of the most intensively studied diarylheptanoid, Curcuma longa being its principal producer. This apart, a class of promising curcumin analogs has been generated in laboratories, aptly named as Curcuminoids which are showing huge potential in the fields of medicine, food technology, etc. The lack of a universal source of data on curcumin as well as curcuminoids has been felt by the curcumin research community for long. Hence, in an attempt to address this stumbling block, we have developed Curcumin Resource Database (CRDB) that aims to perform as a gateway-cum-repository to access all relevant data and related information on curcumin and its analogs. Currently, this database encompasses 1186 curcumin analogs, 195 molecular targets, 9075 peer reviewed publications, 489 patents and 176 varieties of C. longa obtained by extensive data mining and careful curation from numerous sources. Each data entry is identified by a unique CRDB ID (identifier). Furnished with a user-friendly web interface and in-built search engine, CRDB provides well-curated and cross-referenced information that are hyperlinked with external sources. CRDB is expected to be highly useful to the researchers working on structure as well as ligand-based molecular design of curcumin analogs.
authors.affiliation: Bioengineering Research Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Assam 781039, India, Centre for Biological Sciences (Bioinformatics), Central University of South Bihar (CUSB), Patna 800014, India.
authors.forename: Anil
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Bioengineering Research Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Assam 781039, India.
authors.forename: Hasnahana
authors.initials: H
authors.lastname: Chetia
authors.affiliation: Bioengineering Research Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Assam 781039, India.
authors.forename: Swagata
authors.initials: S
authors.lastname: Sharma
authors.affiliation: Bioengineering Research Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Assam 781039, India.
authors.forename: Debajyoti
authors.initials: D
authors.lastname: Kabiraj
authors.affiliation: Institute of Advanced Studies on Science and Technology (IASST) Boragaon, Guwahati, Assam 781035, India and ubora@iitg.ernet.in ubora@rediffmail.com.
authors.forename: Narayan Chandra
authors.initials: NC
authors.lastname: Talukdar
authors.affiliation: Bioengineering Research Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati (IITG), Assam 781039, India, Institutional Biotech Hub, Centre for the Environment, Indian Institute of Technology Guwahati (IITG), Assam 781039, India nctalukdar@yahoo.com.
authors.forename: Utpal
authors.initials: U
authors.lastname: Bora
mesh_terms: D000818:Animals; D030024:Curcuma; D003474:Curcumin / Q000031:analogs & derivatives / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans
chemical_list: D003474:Curcumin