title: Allele frequencies of combined DNA index system (CODIS) and non-CODIS short tandem repeat loci in Goiás, Central Brazil.
abstract: In studies of human identification, obtaining a high standard of outcomes and satisfactory conclusions are directly related to the use of highly polymorphic molecular markers. In addition to the combined DNA index system (CODIS) group, it is also important to implement non-CODIS markers into the analysis, as they increase the power of discrimination. During the identification process, it is essential to consider the genetic variation among distinct groups of populations, as the allele frequencies are directly associated with the power of discrimination. However, the population of Goiás, a State located in Central Brazil, is characterized by a highly mixed population due to its diverse ethnic origins. In this study, a survey of the allelic frequencies in the Goiás population was carried out using a molecular assembly composed of 21 autosomal loci both from and external to the CODIS group. The new data, for some of the markers used, were statistically similar to those from previous studies. This consistency means that the use of these markers might serve as a parameter for future population comparisons. The results from these analyses further our knowledge of the study of human identification.
authors.affiliation: Instituto Nacional de Cursos,Pós-Graduação em Genética e Biologia Molecular, Goiânia, GO, Brasil.
authors.forename: R G
authors.initials: RG
authors.lastname: Rodovalho
authors.affiliation: Instituto Nacional de Cursos,Pós-Graduação em Genética e Biologia Molecular, Goiânia, GO, Brasil.
authors.forename: G S
authors.initials: GS
authors.lastname: Santos
authors.affiliation: Instituto Nacional de Cursos,Pós-Graduação em Genética e Biologia Molecular, Goiânia, GO, Brasil.
authors.forename: L M
authors.initials: LM
authors.lastname: Cavalcanti
authors.affiliation: Instituto Nacional de Cursos,Pós-Graduação em Genética e Biologia Molecular, Goiânia, GO, Brasil.
authors.forename: B F S M
authors.initials: BF
authors.lastname: Moura
authors.affiliation: Promega Corporation, Departamento de Identificação Humana, São Paulo, SP, Brasil.
authors.forename: E L
authors.initials: EL
authors.lastname: Rodrigues
authors.affiliation: BIOCROMA - Clínica de Exames de DNA, Goiânia, GO, Brasil.
authors.forename: P R
authors.initials: PR
authors.lastname: Lima
authors.affiliation: Programa de Pós-Graduação em Biotecnologia e Biodiversidade,Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, GO, Brasil.
authors.forename: M A D
authors.initials: MA
authors.lastname: Gigonzac
authors.affiliation: Laboratório de Citogenética Humana e Genética Molecular (LaGene/Lacen), Secretaria do Estado de Saúde de Goiás, Goiânia, GO, Brasil thaiscidalia@gmail.com.
authors.forename: T C
authors.initials: TC
authors.lastname: Vieira
mesh_terms: D015415:Biomarkers / Q000097:blood; D001938:Brazil; D016172:DNA Fingerprinting / Q000379:methods*; D030541:Databases, Genetic; D005006:Ethnicity / Q000235:genetics; D005787:Gene Frequency; D008040:Genetic Linkage; D005828:Genetics, Population / Q000379:methods; D006801:Humans; D018895:Microsatellite Repeats; D011110:Polymorphism, Genetic
chemical_list: D015415:Biomarkers