title: Benefits of less frequent injections in advanced prostate cancer.
abstract: Leuprorelin is indicated for the palliative treatment of advanced prostate cancer (APC) and is available as 1, 3, 4 and 6-monthly injections. There are advantages of longer leuprorelin injection intervals in the treatment of APC. Across all injection intervals, efficacy is similar and the majority of patients achieve testosterone suppression and normalisation of prostate-specific antigent. Treatment is well tolerated. Six-monthly leuprorelin injections are less costly to the healthcare system than the shorter interval injections.
authors.affiliation: BPharm PhD, Zitro Consulting Services, Artarmon, NSW; and Conjoint Associate Professor, St Vincent's Clinical School, University of New South Wales, Darlinghurst, NSW.
authors.forename: Michael
authors.initials: M
authors.lastname: Ortiz
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D006801:Humans; D007267:Injections; D016729:Leuprolide / Q000008:administration & dosage*; D008297:Male; D010166:Palliative Care / Q000379:methods*; D011471:Prostatic Neoplasms / Q000188:drug therapy*; D018570:Risk Assessment
chemical_list: D018931:Antineoplastic Agents, Hormonal; D016729:Leuprolide