title: Serosurvey of Entamoeba Histolytica Exposure among Tepehuanos Population in Durango, Mexico.
abstract: The seroepidemiology of Entamoeba histolytica infection in Tepehuanos population in Mexico is largely unknown. This study aimed to study the seroprevalence and correlates of E. histolytica antibodies in Tepehuanos in Durango, Mexico. Through a cross-sectional study, we determined the frequency of E. histolytica IgG antibodies in 156 Tepehuanos people in Durango, Mexico using an enzyme-linked immunoassay. Furthermore, we studied the association of E. histolytica seroprevalence with the socio-demographic, clinical, and behavioral characteristics of the Tepehuanos studied. Forty-four (28.2%) Tepehuanos with mean age of 31.03 ± 16.71 years old had anti- E. histolytica IgG antibodies. Multivariate analysis showed that E. histolytica exposure was positively associated with laborer occupation (Odds ratio=2.77; 95% CI: 1.15, 6.66; p=0.02), and history of lymphadenopathy (Odds ratio=4.97; 95% CI: 1.74, 14.13; p=0.002), and negatively associated with soil contact (Odds ratio=0.13; 95% CI: 0.03, 0.53; p=0.004). Other behavioral characteristics including drinking untreated water or unpasteurized milk, and consumption of unwashed raw vegetables or fruits were not associated with E. histolytica exposure. The seroprevalence of E. histolytica infection in Tepehuanos in Durango is higher thanseroprevalences reported in national surveys. The factors associated with E. histolytica seropositivity reported in the present study might aid for the planning and implementation of effective measures against E. histolytica infection.
authors.affiliation: Biomedical Research Laboratory. Faculty of Medicine and Nutrition, Juárez University of Durango State, Durango, Mexico;
authors.forename: Cosme
authors.initials: C
authors.lastname: Alvarado-Esquivel
authors.affiliation: Institute for Scientific Research "Dr. Roberto Rivera Damm", Juárez University of Durango State, Durango, Mexico;
authors.forename: Jesús
authors.initials: J
authors.lastname: Hernández-Tinoco
authors.affiliation: Institute for Scientific Research "Dr. Roberto Rivera Damm", Juárez University of Durango State, Durango, Mexico;
authors.forename: Luis
authors.initials: L
authors.lastname: Francisco Sánchez-Anguiano
authors.affiliation: Clínica de Medicina Familiar. Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. Predio Canoas S/N. 34079 Durango, Mexico.
authors.forename: Agar
authors.initials: A
authors.lastname: Ramos-Nevárez
authors.affiliation: Clínica de Medicina Familiar. Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. Predio Canoas S/N. 34079 Durango, Mexico.
authors.forename: Sandra
authors.initials: S
authors.lastname: Margarita Cerrillo-Soto
authors.affiliation: Clínica de Medicina Familiar. Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. Predio Canoas S/N. 34079 Durango, Mexico.
authors.forename: Carlos
authors.initials: C
authors.lastname: Alberto Guido-Arreola
keywords: Entamoeba histolytica; Mexico; Tepehuanos; risk factors; seroepidemiologic studies