title: Tissue oxygen tension monitoring of organ perfusion: rationale, methodologies, and literature review.
abstract: Tissue oxygen tension is the partial pressure of oxygen within the interstitial space of an organ bed. As it represents the balance between local oxygen delivery and consumption at any given time, it offers a ready monitoring capability to assess the adequacy of tissue perfusion relative to local demands. This review covers the various methodologies used to measure tissue oxygen tension, describes the underlying physiological and pathophysiological principles, and summarizes human and laboratory data published to date.
authors.affiliation: Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower Street, London WC1E 6BT, UK.
authors.forename: V
authors.initials: V
authors.lastname: De Santis
authors.affiliation: Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower Street, London WC1E 6BT, UK m.singer@ucl.ac.uk.
authors.forename: M
authors.initials: M
authors.lastname: Singer
mesh_terms: D001784:Blood Gas Analysis; D006801:Humans; D016343:Monitoring, Intraoperative / Q000295:instrumentation* / Q000379:methods*; D010092:Oximetry / Q000295:instrumentation* / Q000379:methods*; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology*; D010313:Partial Pressure; D012039:Regional Blood Flow
chemical_list: D010100:Oxygen
keywords: monitoring, intensive care; monitoring, intraoperative; monitoring, oxygen; oxygen, tissue