title: Efficiency of Very Low Doses of Antibodies to S100 Protein in the Complex Therapy of Functional Dyspepsia in Children.
abstract: We showed the data on clinical efficiency of low doses of antibodies to brain-specific protein S100 in the complex therapy of schoolchildren with painful variant of functional dyspepsia syndrome. Significant positive effects of the substance on the dynamics of epigastric pain, in particular, its duration, were found. The maximum clinical effect was observed in children with emotional disorders (~1/3 of all examined children). Along with significant decrease in frequency appearance and duration of pain syndrome, the substance also normalized emotional state and improved attention concentration in children.
authors.affiliation: Research Institute of Medical Problems of the North, Siberian Division of Russian Academy of Medical Sciences, Krasnoyarsk, Russia, tamara-polivanova@yandex.ru.
authors.forename: T V
authors.initials: TV
authors.lastname: Polivanova
authors.forename: O V
authors.initials: OV
authors.lastname: Smirnova
authors.forename: N N
authors.initials: NN
authors.lastname: Gorbacheva
authors.forename: V A
authors.initials: VA
authors.lastname: Vshivkov
mesh_terms: D015746:Abdominal Pain / Q000188:drug therapy / Q000276:immunology; D000293:Adolescent; D000906:Antibodies / Q000276:immunology / Q000627:therapeutic use*; D002648:Child; D004415:Dyspepsia / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D011446:Prospective Studies; D009418:S100 Proteins / Q000276:immunology*
chemical_list: D000906:Antibodies; D009418:S100 Proteins