title: Pancreatic exocrine insufficiency in pancreatic cancer: A review of the literature.
abstract: Pancreatic exocrine insufficiency is a well-documented complication of chronic pancreatitis; however, study results of pancreatic exocrine insufficiency in pancreatic cancer are less consistent. This applies for patients who are treated non-surgically and those who undergo curative pancreatic cancer resection. This review article summarizes relevant studies addressing pancreatic exocrine insufficiency in pancreatic cancer, with particular differentiation between non-surgically and surgically treated patients, as well as between the different surgeries. We also summarize studies addressing pancreatic enzyme replacement therapy in pancreatic cancer.
authors.affiliation: Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, United States.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Bartel
authors.affiliation: General Surgery, Mayo Clinic, Jacksonville, FL, United States.
authors.forename: Horatio
authors.initials: H
authors.lastname: Asbun
authors.affiliation: General Surgery, Mayo Clinic, Jacksonville, FL, United States.
authors.forename: John
authors.initials: J
authors.lastname: Stauffer
authors.affiliation: Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, United States. Electronic address: Raimondo.Massimo@mayo.edu.
authors.forename: Massimo
authors.initials: M
authors.lastname: Raimondo
mesh_terms: D013505:Digestive System Surgical Procedures / Q000379:methods; D056947:Enzyme Replacement Therapy; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D010179:Pancreas / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000628:therapy*; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic
keywords: Pancreatic cancer; Pancreatic exocrine insufficiency