title: Genome sequences of copper resistant and sensitive Enterococcus faecalis strains isolated from copper-fed pigs in Denmark.
abstract: Six strains of Enterococcus faecalis (S1, S12, S17, S18, S19 and S32) were isolated from copper fed pigs in Denmark. These Gram-positive bacteria within the genus Enterococcus are able to survive a variety of physical and chemical challenges by the acquisition of diverse genetic elements. The genome of strains S1, S12, S17, S18, S19 and S32 contained 2,615, 2,769, 2,625, 2,804, 2,853 and 2,935 protein-coding genes, with 41, 42, 27, 42, 32 and 44 genes encoding antibiotic and metal resistance, respectively. Differences between Cu resistant and sensitive E. faecalis strains, and possible co-transfer of Cu and antibiotic resistance determinants were detected through comparative genome analysis.
authors.affiliation: Department of Plant and Environmental Science, University of Copenhagen, Frederiksberg, Denmark ; State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.
authors.forename: Siyu
authors.initials: S
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Agricultural Microbiology, College of Life Sciences and Technology, HuaZhong Agricultural University, Wuhan, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Wang
authors.affiliation: Department of Plant and Environmental Science, University of Copenhagen, Frederiksberg, Denmark.
authors.forename: Yihua
authors.initials: Y
authors.lastname: Wang
authors.affiliation: National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.
authors.forename: Henrik
authors.initials: H
authors.lastname: Hasman
authors.affiliation: National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.
authors.forename: Frank M
authors.initials: FM
authors.lastname: Aarestrup
authors.affiliation: Department of Botany and Microbiology, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Hend A
authors.initials: HA
authors.lastname: Alwathnani
authors.affiliation: State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China ; Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, China.
authors.forename: Yong-Guan
authors.initials: YG
authors.lastname: Zhu
authors.affiliation: Department of Plant and Environmental Science, University of Copenhagen, Frederiksberg, Denmark ; Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, China.
authors.forename: Christopher
authors.initials: C
authors.lastname: Rensing
keywords: Antibiotic resistance; Comparative genomics; Copper resistance; Enterococcus faecalis; Genome sequence