title: Independent risk factors for hypoxemia after surgery for acute aortic dissection.
abstract: OBJECTIVE
  To determine risk factors associated with postoperative hypoxemia after surgery for acute type A aortic dissection.
  
  
  METHODS
  We retrospectively analyzed the clinical data of 192 patients with acute type A aortic dissection who underwent surgery in Qingdao Municipal Hospital, Medical College of Qingdao University, Qingdao, China between January 2007 and December 2013. Patients were divided into hypoxemia group (n=55) [arterial partial pressure of oxygen (PaO2)/fraction of inspired oxygen (FiO2) ≤ 200 mm Hg] and non-hypoxemia group (n=137) [PaO2/FiO2 > 200 mm Hg]. Perioperative clinical data were analyzed and compared between the 2 groups.
  
  
  RESULTS
  The incidence of postoperative hypoxemia after surgery for acute aortic dissection was 28.6% (55/192). Perioperative death occurred in 13 patients (6.8%). Multivariate regression identified body mass index (BMI) > 25 kg/m2 (OR=21.929, p=0.000), deep hypothermic circulatory arrest (DHCA) (OR=11.551, p=0.000), preoperative PaO2/FiO2 ≤ 300 mm Hg (OR=7.830, p=0.000) and blood transfusion > 6U in 24 hours postoperatively (OR=12.037, p=0.000) as independent predictors of postoperative hypoxemia for patients undergoing Stanford A aortic dissection surgery.
  
  
  CONCLUSIONS
  Our study demonstrated that BMI > 25 kg/m2, DHCA, preoperative PaO2/FiO2 ≤ 300 mm Hg, and blood transfusion in 24 hours postoperatively > 6U were independent risk factors of the hypoxemia after acute type A aortic dissection aneurysm surgery.
authors.affiliation: Department of Cardiovascular Surgery, Qingdao Municipal Hospital, Medical College of Qingdao University, Qingdao, China. E-mail. sw8011@163.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Sheng
authors.forename: Hai-Qin
authors.initials: HQ
authors.lastname: Yang
authors.forename: Yi-Fan
authors.initials: YF
authors.lastname: Chi
authors.forename: Zhao-Zhuo
authors.initials: ZZ
authors.lastname: Niu
authors.forename: Ming-Shan
authors.initials: MS
authors.lastname: Lin
authors.forename: Sun
authors.initials: S
authors.lastname: Long
mesh_terms: D000784:Aortic Dissection / Q000097:blood / Q000601:surgery*; D001014:Aortic Aneurysm / Q000097:blood / Q000601:surgery*; D001803:Blood Transfusion; D015992:Body Mass Index; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects; D000860:Hypoxia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D011183:Postoperative Complications / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D010100:Oxygen