title: Effect of very early mobilisation on functional status in patients with acute stroke: a single-blind, randomized controlled trail.
abstract: OBJECTIVE
  To evaluate the effect of very early mobilisation on functional status following acute stroke.
  
  
  METHODS
  Single blind, randomized controlled trial.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Eighty-six patients with acute stroke (42 men and 38 women) aged 30-80 years were randomized to an Intervention group and a Standard care group.
  
  
  METHODS
  All participants received 45 minutes standard care once a day for seven days. In addition, the intervention group (n=43) performed very early mobilisation consisting of early and frequent out of bed activities which started within 24 hours of stroke onset for 5 to 30 minutes at least twice a day, for seven days.
  
  
  METHODS
  Functional status was measured with Barthel ADL Index on admission, discharge and three months follow up.
  
  
  RESULTS
  Intervention group showed a significant improvement in Barthel Index change scores (discharge - admission) (median=35, IQR=30-38.75 versus median=17.50, IQR=10-30) than the standard care group. Intervention group showed a significant improvement in Barthel Index change scores (three month follow up - admission) (median=42.50, IQR=35-55) versus (median=30, IQR=20-35) than the standard care group. The Intervention group reported statistically significant improvement in functional status at discharge (P<0.001) and at three months follow up (P<0.001) compared with the Standard care group.
  
  
  CONCLUSIONS
  The results indicate that very early mobilisation in addition to the standard care may be effective in improving the functional status following acute stroke.
authors.affiliation: Nitte Institute of Physiotherapy, Nitte University, Mangalore, India chippala_puru@yahoo.co.in.
authors.forename: Purusotham
authors.initials: P
authors.lastname: Chippala
authors.affiliation: Department of Medicine, K S Hegde Medical Academy, Nitte University, Deralakatte, Mangalore, India.
authors.forename: Raghava
authors.initials: R
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004434:Early Ambulation; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D020127:Recovery of Function / Q000502:physiology*; D016037:Single-Blind Method; D020521:Stroke / Q000150:complications / Q000503:physiopathology*; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome
keywords: Acute stroke; Barthel ADL Index; functional status; standard care (SC); very early mobilisation (VEM)