title: Reducing the price of treatment for multidrug-resistant tuberculosis through the Global Drug Facility.
abstract: OBJECTIVE
  Many countries have limited experience of securing the best prices for drugs and have little negotiating power. This is particularly true for the complex, lengthy and expensive regimens used to treat multidrug-resistant tuberculosis.
  
  
  METHODS
  The Stop TB Partnership's Global Drug Facility is dedicated to improving worldwide access to antituberculosis medicines and diagnostic techniques that meet international quality standards.
  
  
  METHODS
  The Global Drug Facility is able to secure price reductions through competitive tendering among prequalified drug manufacturers and by consolidating orders to achieve large purchase volumes. Consolidating the market in this way increases the incentives for suppliers of quality-assured medicines.
  
  
  RESULTS
  In 2013 the Global Drug Facility reduced the price of the second-line drugs it supplies for multidrug-resistant tuberculosis: the overall cost of the longest and most expensive treatment regimen for a patient decreased by 26% - from 7890 United States dollars (US$) in 2011 to US$ 5822 in 2013.
  
  
  CONCLUSIONS
  The price of treatment for multidrug-resistant tuberculosis supplied by the Global Drug Facility was reduced by consolidating orders to achieve large purchase volumes, by international, competitive bidding and by the existence of donor-funded medicine stockpiles. The rise in the number of suppliers of internationally quality-assured drugs was also important. The savings achieved from lower drug costs could be used to increase the number of patients on high-quality treatment.
authors.affiliation: Stop TB Partnership, Chemin de Blandonnet 2, 1214 Geneva, Switzerland .
authors.forename: Kaspars
authors.initials: K
authors.lastname: Lunte
authors.affiliation: World Health Organization, Geneva, Switzerland .
authors.forename: Thierry
authors.initials: T
authors.lastname: Cordier-Lassalle
authors.affiliation: Stop TB Partnership, Chemin de Blandonnet 2, 1214 Geneva, Switzerland .
authors.forename: Joel
authors.initials: J
authors.lastname: Keravec
mesh_terms: D000995:Antitubercular Agents / Q000191:economics / Q000600:supply & distribution / Q000627:therapeutic use; D003132:Commerce; D016527:Drug Costs; D004345:Drug Industry / Q000191:economics / Q000379:methods; D006293:Health Promotion / Q000379:methods; D006297:Health Services Accessibility; D006801:Humans; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy*; D014481:United States
chemical_list: D000995:Antitubercular Agents