title: Optimal Antibiotic Dosage for Chronic Kidney Disease Patient: A Pharmacological Manual for Oral Clinicians.
abstract: Chronic kidney disease, (CKD) a gradual and inevitable deterioration in renal function, is the disease with the most associations in dentistry. Dosage adjustment is one amongst the vital elements to be familiar with during their oral care. CKD patients take extended duration to filter out medications, therefore dosage must always be tailored under the supervision of nephrologist. The relished benefits from antibiotic could transform as anti-microbial resistance on their abuse and nephrotoxic when contraindicated drugs are encouraged. New patented drug belonging to oxazoliodine group has driven the researchers to handle the emerging AMR. The present communication discusses the pharmacological factors influencing in prescribing the antibiotics for CKD patient from the dentist's point of view. The formulas destined for calculating the optimal dosage of antibiotics have been documented to aid oral physicians.
authors.affiliation: Department of Prosthodontics, Faculty of Dentistry, AIMST University, Jalan Bedong, Semeling 08100, Kedah Darul Aman, Malaysia. dr.ramasamyc@gmail.com.
authors.forename: Ramasamy
authors.initials: R
authors.lastname: Chidambaram
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D000075202:Contraindications; D003813:Dentistry / Q000379:methods*; D054796:Drug Dosage Calculations; D015507:Drugs, Investigational / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D051436:Renal Insufficiency, Chronic / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D015507:Drugs, Investigational