title: The challenge of detecting herds sub-clinically infected with Actinobacillus pleuropneumoniae.
abstract: The introduction into a naïve herd of animals sub-clinically infected with Actinobacillus pleuropneumoniae (App) is frequently the cause of clinical pleuropneumonia and the identification of such infected herds is a priority in the control of disease. Different serological tests for App have been developed and a number of these are routinely used. Some are species-specific whereas others identify more specifically the serotype/serogroup involved which requires updated information about important serotypes recovered from diseased pigs in a given area/country. Serotyping methods based on molecular techniques have been developed lately and are ready to be used by most diagnostic laboratories. When non-conclusive serological results are obtained, direct detection of App from tonsils is sometimes attempted. This review addresses different techniques and approaches used to monitor herds sub-clinically infected by this important pathogen.
authors.affiliation: Department of Pathology and Microbiology, Swine and Poultry Infectious Disease Center (CRIPA), Groupe de Recherche sur les Maladies Infectieuses du Porc (GREMIP), Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, Québec, Canada J2S 2M2. Electronic address: marcelo.gottschalk@umontreal.ca.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Gottschalk
mesh_terms: D000189:Actinobacillus Infections / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D016977:Actinobacillus pleuropneumoniae / Q000145:classification; D000818:Animals; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis / Q000382:microbiology*
keywords: Actinobacillus pleuropneumoniae; Carrier animals; Direct detection; ELISA; PCR; Serology; Serotyping