title: Effects of Glaucoma Tube Surgery on Corneal Endothelial Cells: A Review.
abstract: The etiology of corneal decompensation after aqueous shunt implantation remains poorly understood. With the use of anterior segment optical coherence tomography and specular microscopy, the relationship of these implants to the surrounding tissues can be investigated over time. This article will review the current knowledge pertaining to endothelial cell loss related to glaucoma and surgery and highlight possible causes that have been proposed for endothelial cell loss after aqueous shunt implantation.
authors.affiliation: Department of Ophthalmology (E.B.K., J.D.K., R.L.S., Y.H.), UC San Francisco, San Francisco, CA; Department of Ophthalmology (J.H.), People's Hospital, Peking University, Beijing, China; Francis I. Proctor Foundation (J.D.K.), UC San Francisco, San Francisco, CA; and Department of Ophthalmology and Visual Sciences (B.H.J.), University of Maryland School of Medicine, Baltimore, MD.
authors.forename: Euna B
authors.initials: EB
authors.lastname: Koo
authors.forename: Jing
authors.initials: J
authors.lastname: Hou
authors.forename: Jeremy D
authors.initials: JD
authors.lastname: Keenan
authors.forename: Robert L
authors.initials: RL
authors.lastname: Stamper
authors.forename: Bennie H
authors.initials: BH
authors.lastname: Jeng
authors.forename: Ying
authors.initials: Y
authors.lastname: Han
mesh_terms: D001082:Aqueous Humor / Q000502:physiology; D003316:Corneal Diseases / Q000209:etiology / Q000473:pathology; D042783:Endothelial Cells / Q000473:pathology / Q000502:physiology; D004728:Endothelium, Corneal / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D005355:Fibrosis / Q000517:prevention & control / Q000628:therapy; D005901:Glaucoma / Q000601:surgery*; D020327:Glaucoma Drainage Implants / Q000009:adverse effects*; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D041623:Tomography, Optical Coherence; D014130:Trabeculectomy / Q000009:adverse effects