title: Regulated degradation: controlling the stability of autophagy gene transcripts.
abstract: Autophagy is involved in diverse cellular functions through degradation of various intracellular constituents, and hence must be tightly controlled. A recent study by Hu et al. (2015) in Nature Cell Biology adds a new layer of autophagy regulation, involving Tor kinase-driven degradation of mRNAs encoding autophagy-related proteins.
authors.affiliation: Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama 226-8503, Japan; CREST, Japan Science and Technology Agency, Saitama 332-0012, Japan. Electronic address: hnakatogawa@bio.titech.ac.jp.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Nakatogawa
mesh_terms: D000818:Animals; D001343:Autophagy / Q000235:genetics*; D053487:DEAD-box RNA Helicases / Q000235:genetics*; D005260:Female; D006801:Humans; D020871:RNA Stability / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics*
chemical_list: D029701:Saccharomyces cerevisiae Proteins; D053487:DEAD-box RNA Helicases