title: One shot of carbon-ion radiotherapy cured a 6-cm chemo-resistant metastatic liver tumor: a case of breast cancer.
abstract: The standard treatment for metastatic liver tumor from breast cancer is systemic medical treatment, and there is controversy regarding the value of local treatment. However, there are some exceptional cases that do benefit from local therapy. We describe the case of a 54-year-old woman with systemic therapy-resistant liver metastasis from breast cancer successfully treated with a single shot of 36-GyE carbon-ion radiotherapy and surviving more than 8 years without local recurrence. This case represents a good example of the usefulness and safety of carbon-ion radiotherapy, and who might benefit from local therapy.
authors.affiliation: Department of Radiation Oncology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata, Yamagata, 990-9585, Japan. ideal.fullmoon@gmail.com.|Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan. ideal.fullmoon@gmail.com.
authors.forename: Mayumi
authors.identifier: http://orcid.org/0000-0001-8869-6548
authors.initials: M
authors.lastname: Harada
authors.affiliation: Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
authors.forename: Kumiko
authors.initials: K
authors.lastname: Karasawa
authors.affiliation: Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
authors.forename: Shigeo
authors.initials: S
authors.lastname: Yasuda
authors.affiliation: Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kamada
authors.affiliation: Department of Radiation Oncology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata, Yamagata, 990-9585, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Nemoto
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D063193:Heavy Ion Radiotherapy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000556:secondary*; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000188:drug therapy / Q000532:radiotherapy* / Q000556:secondary; D016896:Treatment Outcome
keywords: Breast cancer; Carbon-ion radiotherapy; Metastatic liver tumor