title: Community Trial of a Faith-Based Lifestyle Intervention to Prevent Diabetes Among African-Americans.
abstract: About 75% of African-Americans (AAs) ages 20 or older are overweight and nearly 50% are obese, but community-based programs to reduce diabetes risk in AAs are rare. Our objective was to reduce weight and fasting plasma glucose (FPG) and increase physical activity (PA) from baseline to week-12 and to month-12 among overweight AA parishioners through a faith-based adaptation of the Diabetes Prevention Program called Fit Body and Soul (FBAS). We conducted a single-blinded, cluster randomized, community trial in 20 AA churches enrolling 604 AAs, aged 20-64 years with BMI ≥ 25 kg/m(2) and without diabetes. The church (and their parishioners) was randomized to FBAS or health education (HE). FBAS participants had a significant difference in adjusted weight loss compared with those in HE (2.62 vs. 0.50 kg, p = 0.001) at 12-weeks and (2.39 vs. -0.465 kg, p = 0.005) at 12-months and were more likely (13%) than HE participants (3%) to achieve a 7% weight loss (p < 0.001) at 12-weeks and a 7% weight loss (19 vs. 8%, p < 0.001) at 12-months. There were no significant differences in FPG and PA between arms. Of the 15.2% of participants with baseline pre-diabetes, those in FBAS had, however, a significant decline in FPG (10.93 mg/dl) at 12-weeks compared with the 4.22 mg/dl increase in HE (p = 0.017), and these differences became larger at 12-months (FBAS, 12.38 mg/dl decrease; HE, 4.44 mg/dl increase) (p = 0.021). Our faith-based adaptation of the DPP led to a significant reduction in weight overall and in FPG among pre-diabetes participants. CLINICALTRIALS.
  NCT01730196.
authors.affiliation: Department of Emergency Medicine, Medical College of Georgia, Georgia Regents University, 1120 15th Street, AF-1001, Augusta, GA, 30912, USA. rsattin@gru.edu.|College of Nursing, Georgia Regents University, 987 St. Sebastian Way, Augusta, GA, 30912, USA. rsattin@gru.edu.
authors.forename: Richard W
authors.initials: RW
authors.lastname: Sattin
authors.affiliation: College of Nursing, Georgia Regents University, 987 St. Sebastian Way, Augusta, GA, 30912, USA.
authors.forename: Lovoria B
authors.initials: LB
authors.lastname: Williams
authors.affiliation: Department of Biostatistics and Epidemiology, Medical College of Georgia, Georgia Regents University, 1120 15th Street, AE-1036, Augusta, GA, 30912, USA.
authors.forename: James
authors.initials: J
authors.lastname: Dias
authors.affiliation: College of Nursing, Georgia Regents University, 987 St. Sebastian Way, Augusta, GA, 30912, USA.
authors.forename: Jane T
authors.initials: JT
authors.lastname: Garvin
authors.affiliation: College of Nursing, Georgia Regents University, 987 St. Sebastian Way, Augusta, GA, 30912, USA.
authors.forename: Lucy
authors.initials: L
authors.lastname: Marion
authors.affiliation: College of Nursing, Georgia Regents University, 987 St. Sebastian Way, Augusta, GA, 30912, USA.
authors.forename: Thomas V
authors.initials: TV
authors.lastname: Joshua
authors.affiliation: Department of Epidemiology, University of Pittsburgh, 505B Parran Hall, Pittsburgh, PA, 15261, USA.
authors.forename: Andrea
authors.initials: A
authors.lastname: Kriska
authors.affiliation: Department of Epidemiology, University of Pittsburgh, 505B Parran Hall, Pittsburgh, PA, 15261, USA.
authors.forename: M Kaye
authors.initials: MK
authors.lastname: Kramer
authors.affiliation: Hubert Department of Global Health, Emory University, 1518 Clifton Road NE, Room 7040 N., Atlanta, GA, 30322, USA.
authors.forename: K M Venkat
authors.initials: KM
authors.lastname: Narayan
mesh_terms: D000328:Adult; D001741:Black or African American; D001786:Blood Glucose; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000208:ethnology / Q000517:prevention & control*; D015444:Exercise; D005260:Female; D006266:Health Education / Q000458:organization & administration*; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000208:ethnology / Q000628:therapy; D050177:Overweight / Q000208:ethnology / Q000628:therapy*; D012067:Religion; D012307:Risk Factors; D016037:Single-Blind Method; D012959:Socioeconomic Factors; D014481:United States / Q000453:epidemiology; D015431:Weight Loss; D061217:Weight Reduction Programs / Q000458:organization & administration*
chemical_list: D001786:Blood Glucose
keywords: African-American; Diabetes prevention; Obesity; Translation research