title: Controversies in the Management of Vesicoureteral Reflux.
abstract: Vesicoureteral reflux (VUR) is the abnormal retrograde flow of urine from the bladder into the upper urinary tract. Diagnosis and subsequent management of VUR have become increasingly controversial, with differing opinions over which children should be evaluated for reflux, and when detected, who should undergo treatment. Management goals include prevention of recurrent febrile urinary tract infection (fUTI) and renal injury while minimizing the morbidity of treatment and follow-up. Management options include observation with or without continuous antibiotic prophylaxis and surgical correction via endoscopic, open or laparoscopic/robotic approaches. Management should be individualized and based on patient age, health, risk of subsequent renal injury, clinical course, renal function, and parental preference.
authors.affiliation: Departments of Urology and Pediatrics, The University of Iowa, 200 Hawkins Drive, 3RCP, Iowa City, IA, 52242-1089, USA, angela-arlen@uiowa.edu.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Arlen
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Cooper
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006801:Humans; D010535:Laparoscopy; D012008:Recurrence; D012307:Risk Factors; D065287:Robotic Surgical Procedures; D014718:Vesico-Ureteral Reflux / Q000517:prevention & control / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents