title: Using proteomic and genomic methods to understand JDM.
abstract: Juvenile dermatomyositis is a complex illness characterized by vascular/perivascular inflammation, primarily in the skin and muscles. In this review, we discuss how proteomic and genomic technologies have expanded our understanding of the immune pathogenesis of this disease. We will also discuss further directions that the field may take to use existing and developing technologies to further our understanding of this often-perplexing disease.
authors.affiliation: Department of Pediatrics and Genetics, Genomics & Bioinformatics Program, University at Buffalo.
authors.forename: Rie
authors.initials: R
authors.lastname: Karasawa
authors.forename: James N
authors.initials: JN
authors.lastname: Jarvis
mesh_terms: D001323:Autoantibodies / Q000276:immunology; D015415:Biomarkers / Q000032:analysis; D003882:Dermatomyositis / Q000235:genetics / Q000276:immunology*; D042783:Endothelial Cells / Q000276:immunology; D020869:Gene Expression Profiling; D023281:Genomics; D006801:Humans; D040901:Proteomics; D014158:Transcription, Genetic
chemical_list: D001323:Autoantibodies; D015415:Biomarkers