title: [Unclear retinopathy after intravitreal injection of ocriplasmin].
abstract: METHODS
  This article reports the case of a 50-year-old female patient who presented with reduced visual acuity of 0.8 p and metamorphopsia of the left eye caused by focal vitreomacular traction and who was treated with intravitreal Jetrea® (ocriplasmin). After injection the patient suffered from progressive nyctalopia and visual field defects. Electroretinography (ERG) showed decreased amplitudes and optical coherence tomography (OCT) showed decreased reflectivity in the ellipsoid layer that persisted for 2 months after treatment.
  
  
  CONCLUSIONS
  Before injection of Jetrea® a detailed clarification of such potential side effects is necessary to increase patient compliance in the follow-up.
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Augenklinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstraße 22, 81675, München, Deutschland. Sophia.Abraham@mri.tum.de.
authors.forename: S
authors.initials: S
authors.lastname: Abraham
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Augenklinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstraße 22, 81675, München, Deutschland.
authors.forename: K
authors.initials: K
authors.lastname: Wand
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Augenklinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstraße 22, 81675, München, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Stumpfe
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Augenklinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstraße 22, 81675, München, Deutschland.
authors.forename: N
authors.initials: N
authors.lastname: Feucht
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Augenklinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstraße 22, 81675, München, Deutschland.
authors.forename: C P
authors.initials: CP
authors.lastname: Lohmann
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Augenklinik, Klinikum rechts der Isar, Technische Universität München, Ismaningerstraße 22, 81675, München, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Maier
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005341:Fibrinolysin / Q000008:administration & dosage* / Q000009:adverse effects*; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D058449:Intravitreal Injections / Q000009:adverse effects*; D008875:Middle Aged; D009755:Night Blindness / Q000139:chemically induced* / Q000175:diagnosis* / Q000517:prevention & control; D010446:Peptide Fragments / Q000008:administration & dosage* / Q000009:adverse effects*; D012164:Retinal Diseases; D020255:Vitreous Detachment / Q000150:complications / Q000188:drug therapy*
chemical_list: D005343:Fibrinolytic Agents; D010446:Peptide Fragments; C054561:microplasmin; D005341:Fibrinolysin
keywords: Optical coherence tomography; Retina; Visual field; Visual loss; Vitreomacular traction