title: Genomic medicine in gastroenterology: A new approach or a new specialty?
abstract: Throughout history, many medical milestones have been achieved to prevent and treat human diseases. Man's early conception of illness was naturally holistic or integrative. However, scientific knowledge was atomized into quantitative and qualitative research. In the field of medicine, the main trade-off was the creation of many medical specialties that commonly treat patients in advanced stages of disease. However, now that we are immersed in the post-genomic era, how should we reevaluate medicine? Genomic medicine has evoked a medical paradigm shift based on the plausibility to predict the genetic susceptibility to disease. Additionally, the development of chronic diseases should be viewed as a continuum of interactions between the individual's genetic make-up and environmental factors such as diet, physical activity, and emotions. Thus, personalized medicine is aimed at preventing or reversing clinical symptoms, and providing a better quality of life by integrating the genetic, environmental and cultural factors of diseases. Whether using genomic medicine in the field of gastroenterology is a new approach or a new medical specialty remains an open question. To address this issue, it will require the mutual work of educational and governmental authorities with public health professionals, with the goal of translating genomic medicine into better health policies.
authors.affiliation: Sonia Roman, Arturo Panduro, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco 44280, Mexico.
authors.forename: Sonia
authors.initials: S
authors.lastname: Roman
authors.affiliation: Sonia Roman, Arturo Panduro, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara, "Fray Antonio Alcalde", Mexico and Health Sciences Center, University of Guadalajara, Guadalajara, Jalisco 44280, Mexico.
authors.forename: Arturo
authors.initials: A
authors.lastname: Panduro
mesh_terms: D004066:Digestive System Diseases / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D005762:Gastroenterology / Q000379:methods*; D059647:Gene-Environment Interaction; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D023281:Genomics; D006801:Humans; D010641:Phenotype; D057285:Precision Medicine; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors; D013038:Specialization
chemical_list: D005819:Genetic Markers
keywords: Chronic diseases; Gastrointestinal diseases; Liver disease; Nutritional genomics; Obesity