title: Passenger Mutations Identified in the Blink of an Eye.
abstract: Passenger mutations specific to particular mouse strains can distort experimental outcomes. In this issue of Immunity, Vanden Berghe et al. (2015) demonstrate that passenger mutations are frequent in most genetically engineered congenic mice and persist even after extensive backcrossing.
authors.affiliation: The Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2M9, Canada.
authors.forename: Robert
authors.initials: R
authors.lastname: Nechanitzky
authors.affiliation: The Campbell Family Institute for Breast Cancer Research, Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2M9, Canada. Electronic address: tmak@uhnresearch.ca.
authors.forename: Tak Wah
authors.initials: TW
authors.lastname: Mak
mesh_terms: D000818:Animals; D014644:Genetic Variation / Q000235:genetics*; D016678:Genome / Q000235:genetics*; D008810:Mice, Inbred C57BL / Q000235:genetics*