title: Clinical relevance of quality of life in laryngomalacia.
abstract: To examine aspects of laryngomalacia and correlate findings with quality of life (QOL).
  
  
  
  Prospective cross-sectional study.
  
  
  
  Seventy-two patients with laryngomalacia were examined; the mean age was 8.8 weeks. Parents answered questions from the Infant and Toddler Quality of Life Questionnaire-47 (ITQOL-SF47). Fiberoptic laryngoscopy and endoscopic examination of swallowing (FEES) were performed. The presence of laryngomalacia-associated characteristics and swallowing status were recorded. Patient age, sex, presence of reflux, clinical severity, anatomical findings, and swallowing results were evaluated through logistic regression. Independent sample t tests were used to compare responses on the ITQOL-SF47. Overall laryngomalacia ITQOL-SF47 scores were compared to the scores of a large healthy sample population.
  
  
  
  Forty-three (60%) patients had mild laryngomalacia, and 61 (85%) patients had findings suggesting gastroesophageal reflux disease. The most common abnormality was shortened aryepiglottic folds. Ten patients failed FEES. Patients with moderate laryngomalacia (χ = 7.62; P = .006) or prolapsing cuneiforms (χ = 4.79; P = .029) were more likely to fail FEES. Laryngomalacia severity impacted parental perception of their child's health (P < .05). Parents of children who demonstrated aspiration or penetration reported significant emotional impact (mean = 56.9; t = 2.74; P = .008). The mean ITQOL-SF47 scores of patients were significantly lower in certain sections than the reported general sample population.
  
  
  
  Epiglottal prolapse correlated with severity of laryngomalacia and cuneiform prolapse with swallowing dysfunction. Perceptions of worsening health and physical ability were related to severity of disease. Swallowing dysfunction had a significant emotional impact on parental daily life. Infants with laryngomalacia have a lower QOL LEVEL OF EVIDENCE: 3 Laryngoscope, 126:1232-1235, 2016.
authors.affiliation: Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
authors.forename: Prasad John
authors.initials: PJ
authors.lastname: Thottam
authors.affiliation: Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
authors.forename: Jeffrey P
authors.initials: JP
authors.lastname: Simons
authors.affiliation: Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
authors.forename: Sukgi
authors.initials: S
authors.lastname: Choi
authors.affiliation: Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
authors.forename: Raymond
authors.initials: R
authors.lastname: Maguire
authors.affiliation: Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
authors.forename: Deepak K
authors.initials: DK
authors.lastname: Mehta
mesh_terms: D003679:Deglutition; D003680:Deglutition Disorders / Q000209:etiology; D004825:Epiglottis; D005260:Female; D005764:Gastroesophageal Reflux / Q000209:etiology; D006801:Humans; D007223:Infant; D007818:Laryngeal Diseases; D055092:Laryngomalacia / Q000145:classification / Q000150:complications / Q000503:physiopathology; D007828:Laryngoscopy; D016015:Logistic Models; D008297:Male; D010290:Parents; D011391:Prolapse; D011788:Quality of Life; D012135:Respiratory Sounds / Q000209:etiology; D012720:Severity of Illness Index
keywords: Airway; aspiration; flexible endoscopic evaluation of swallowing; laryngomalacia; pediatrics; quality of life; swallowing