title: Thyroidectomy: Natural drainage or negative drainage? Experience with randomized single-center study.
abstract: OBJECTIVE
  The aim is to investigate, in relation to the volume of blood drained, which type drainage to use after thyroidectomy natural drainage or negative drainage.
  
  
  METHODS
  141 patients who underwent total thyroidectomy for multinodular thyroid disease between 22 November 2012 and 7 November 2013 were included in the present study. For the 141 patients a randomized method was used with closed circuit natural drainage (59 cases) or negative drainage (82 cases). The evaluation of the drained volume was performed 24, 48 and 72 hours following surgery.
  
  
  RESULTS
  The amount of blood drained during the first 24 hours of the postoperative period averaged 78.59 ml in patients with a negative drain and 54.24 ml in those under natural drainage. After 48 hours, the total volume in the first group was 117.98 ml, while in the second group it was 85.18 ml. In cases where the observation was prolonged up to 72 hours, the average volume was 217 ml in the 10 cases of negative drainage and 117.5 ml in the 4 cases of natural drainage.
  
  
  CONCLUSIONS
  The difference in blood volume observed between the two groups of patients with natural drainage and negative drainage, leads us to conclude that the best drainage in thyroidectomy is the natural one, diverging from the older concept of the use of negative drainage in superficial cavities.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Lo Bianco
authors.forename: Dario
authors.initials: D
authors.lastname: Cavallaro
authors.forename: Valeriya
authors.initials: V
authors.lastname: Okatyeva
authors.forename: Antonino
authors.initials: A
authors.lastname: Buffone
authors.forename: Matteo Angelo
authors.initials: MA
authors.lastname: Cannizzaro
mesh_terms: D004322:Drainage / Q000379:methods*; D006801:Humans; D013959:Thyroid Diseases / Q000601:surgery*; D013965:Thyroidectomy