title: Extracorporeal shock wave lithotripsy versus retrograde intrarenal surgery for treatment for renal stones 1-2 cm: a meta-analysis.
abstract: This study is to evaluate the efficacy and safety of extracorporeal shock wave lithotripsy (ESWL) versus retrograde intrarenal surgery (RIRS) for the treatment for renal calculi 1-2 cm. PubMed, Embase, the Cochrane Central Register of Controlled Trials, and the Chinese Biomedical Literature Database were researched and hand-searched for relevant congress abstracts and journals about RIRS and ESWL for the treatment for 1- to 2-cm renal stones. The retrieval time ended in September 2014. The related trials met the inclusion criteria were included in the meta-analysis. Two reviewers independently assessed the quality of all included studies, and meta-analysis was performed with RevMan 5.2. Seven literatures were retrieved, including 983 patients. The meta-analysis results showed that, compared to RIRS group, the patients in ESWL group had the following features:(1) the stone-free rate [relative risk (RR) 0.86; 95% confidence interval (CI) 0.77-0.95, P = 0.005] was significantly different between two groups; (2) The retreatment rate of RIRS group was lower (RR 8.12; 95% CI 4.77-13.83, P < 0.00); (3) The complications were not significantly different between two groups (Grade I RR 1.06; 95% CI 0.67-1.69, P = 0.80; Grade II RR 0.75; 95% CI 0.29-1.91, P = 0.54; Grade III RR 0.86; 95% CI 0.26-2.86, P = 0.80). Compared to ESWL, our results showed that RIRS provided significantly higher stone-free rate and lower retreatment rate and without increase in the incidence of complications. However, further randomized trials are needed to confirm these findings.
authors.affiliation: Department of Urology, The People's Hospital of Bishan District, Bishan, Chongqing, 402760, China. zcj2010110649@sina.cn.
authors.forename: Changjian
authors.initials: C
authors.lastname: Zheng
authors.affiliation: Department of Urology, The People's Hospital of Bishan District, Bishan, Chongqing, 402760, China. 617253434@qq.com.
authors.forename: Hongmei
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of Urology, The People's Hospital of Bishan District, Bishan, Chongqing, 402760, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Luo
authors.affiliation: Department of Urology, The People's Hospital of Bishan District, Bishan, Chongqing, 402760, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Xiong
authors.affiliation: Department of Urology, The People's Hospital of Bishan District, Bishan, Chongqing, 402760, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Urology, Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400016, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Jiang
mesh_terms: D006801:Humans; D007669:Kidney Calculi / Q000601:surgery*; D008096:Lithotripsy / Q000009:adverse effects / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D013520:Urologic Surgical Procedures / Q000009:adverse effects / Q000706:statistics & numerical data*
keywords: Extracorporeal shock wave lithotripsy; Renal stones; Retrograde intrarenal surgery