title: Exploring bubble oscillation and mass transfer enhancement in acoustic-assisted liquid-liquid extraction with a microfluidic device.
abstract: We investigated bubble oscillation and its induced enhancement of mass transfer in a liquid-liquid extraction process with an acoustically-driven, bubble-based microfluidic device. The oscillation of individually trapped bubbles, of known sizes, in microchannels was studied at both a fixed frequency, and over a range of frequencies. Resonant frequencies were analytically identified and were found to be in agreement with the experimental observations. The acoustic streaming induced by the bubble oscillation was identified as the cause of this enhanced extraction. Experiments extracting Rhodanmine B from an aqueous phase (DI water) to an organic phase (1-octanol) were performed to determine the relationship between extraction efficiency and applied acoustic power. The enhanced efficiency in mass transport via these acoustic-energy-assisted processes was confirmed by comparisons against a pure diffusion-based process.
authors.affiliation: 1] Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, USA [2] Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Xie
authors.affiliation: Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Chandraprakash
authors.initials: C
authors.lastname: Chindam
authors.affiliation: Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Nitesh
authors.initials: N
authors.lastname: Nama
authors.affiliation: Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Shikuan
authors.initials: S
authors.lastname: Yang
authors.affiliation: Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Mengqian
authors.initials: M
authors.lastname: Lu
authors.affiliation: Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Yanhui
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Mechanical and Biomedical Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR.
authors.forename: John D
authors.initials: JD
authors.lastname: Mai
authors.affiliation: 1] Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA [2] Center for Neural Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Francesco
authors.initials: F
authors.lastname: Costanzo
authors.affiliation: 1] Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, USA [2] Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA [3] Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.
authors.forename: Tony Jun
authors.initials: TJ
authors.lastname: Huang
mesh_terms: D020003:1-Octanol / Q000737:chemistry; D000162:Acoustics; D000465:Algorithms; D004058:Diffusion; D059625:Liquid-Liquid Extraction; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D012235:Rhodamines / Q000737:chemistry / Q000302:isolation & purification; D014867:Water / Q000737:chemistry
chemical_list: D012235:Rhodamines; D014867:Water; C029773:rhodamine B; D020003:1-Octanol