title: Palladium-Catalyzed Hydroamidocarbonylation of Olefins to Imides.
abstract: Carbonylation reactions allow the efficient synthesis of all kinds of carbonyl-containing compounds. Here, we report a straightforward synthesis of various imides from olefins and CO for the first time. The established hydroamidocarbonylation reaction affords imides in good yields (up to 90 %) and with good regioselectivity (up to 99:1) when applying different alkenes and amides. The synthetic potential of the method is highlighted by the synthesis of Aniracetam by intramolecular hydroamidocarbonylation.
authors.affiliation: Leibniz-Institut für Katalyse e. V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock (Germany).
authors.forename: Haoquan
authors.initials: H
authors.lastname: Li
authors.affiliation: Leibniz-Institut für Katalyse e. V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock (Germany).
authors.forename: Kaiwu
authors.initials: K
authors.lastname: Dong
authors.affiliation: Leibniz-Institut für Katalyse e. V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock (Germany).
authors.forename: Helfried
authors.initials: H
authors.lastname: Neumann
authors.affiliation: Leibniz-Institut für Katalyse e. V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock (Germany). matthias.beller@catalysis.de.
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
keywords: alkenes; amides; carbonylation; homogeneous catalysis; imides