title: Endometrial adenocarcinoma in spontaneous abortion: two cases and review of the literature.
abstract: OBJECTIVE
  To report two extremely rare cases of endometrial adenocarcinoma established during the first trimester.
  
  
  METHODS
  A 40-year-old (gravida 0, para 0) and 33-year-old (gravida 4, para 0) woman, were diagnosed with a well-differentiated adenocarcinoma after a dilatation and curettage (D&C) for spontaneous abortions at 8 and 9 gestational weeks, respectively.
  
  
  CONCLUSIONS
  Thirty-six cases of pregnancy-associated endometrial cancer and 20 cases of first trimester pregnancy concurrent with endometrial carcinoma have been reported as present cases in the literature. Interestingly, 15 including our two cases were detected for spontaneous abortions in first-trimester suggesting a causal correlation between endometrial adenocarcinoma and spontaneous abortions. Repeated D&C and progesterone administration may be appropriate for patients who wish to preserve fertility.
authors.affiliation: Department of Pathology, Women's Hospital, School of Medicine, Zhejiang University Hangzhou, Zhejiang Province, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhou
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University Hangzhou, Zhejiang Province, China.
authors.forename: Zhida
authors.initials: Z
authors.lastname: Qian
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University Hangzhou, Zhejiang Province, China.
authors.forename: Yinghua
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Ultrasound, Women's Hospital, School of Medicine, Zhejiang University Hangzhou, Zhejiang Province, China.
authors.forename: Jiale
authors.initials: J
authors.lastname: Qin
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University Hangzhou, Zhejiang Province, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Huang
keywords: Endometrial adenocarcinoma; early pregnancy; spontaneous abortions