title: Validation of the French translation-adaptation of the impact of cancer questionnaire version 2 (IOCv2) in a breast cancer survivor population.
abstract: BACKGROUND
  The Impact of Cancer version 2 (IOCv2) was designed to assess the physical and psychosocial health experience of cancer survivors through its positive and negative impacts. Although the IOCv2 is available in English and Dutch, it has not yet been validated for use in French-speaking populations. The current study was undertaken to provide a comprehensive assessment of the reliability and validity of the French language version of the IOCv2 in a sample of breast cancer survivors.
  
  
  METHODS
  An adapted French version of the IOCv2 as well as demographic and medical information were completed by 243 women to validate the factor structure divergent/divergent validities and reliability. Concurrent validity was assessed by correlating the IOCv2 scales with measures from the SF-12, PostTraumatic Growth Inventory and Fear of Cancer Recurrence Inventory.
  
  
  RESULTS
  The French version of the IOCv2 supports the structure of the original version, with four positive impact dimensions and four negative impact dimensions. This result was suggested by the good fit of the confirmatory factor analysis and the adequate reliability revealed by Cronbach's alpha coefficients and other psychometric indices. The concurrent validity analysis revealed patterns of association between IOCv2 scale scores and other measures. Unlike the original version, a structure with a Positive Impact domain consisting in the IOCv2 positive dimensions and a Negative Impact domain consisting in the negative ones has not been clearly evidenced in this study. The limited practical use of the conditional dimensions Employment Concerns and Relationship Concerns, whether the patient is partnered or not, did not make possible to provide evidence of validity and reliability of these dimensions as the subsets of sample to work with were not large enough. The scores of these conditional dimensions have to be used with full knowledge of the facts of this limitation of the study.
  
  
  CONCLUSIONS
  Integrating IOCv2 into studies will contribute to evaluate the psychosocial health experience of the growing population of cancer survivors, enabling better understanding of the multi-dimensional impact of cancer.
authors.affiliation: EA4275, Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences, University of Nantes, Nantes, France. myriam.blanchin@univ-nantes.fr.
authors.forename: Myriam
authors.initials: M
authors.lastname: Blanchin
authors.affiliation: Psycho-oncology Unit, Department of Supportive Care, Gustave Roussy, Villejuif, France. sarah.dauchy@gustaveroussy.fr.
authors.forename: Sarah
authors.initials: S
authors.lastname: Dauchy
authors.affiliation: Psycho-oncology Unit, Department of Supportive Care, Gustave Roussy, Villejuif, France. alejandra.cano@gustaveroussy.fr.
authors.forename: Alejandra
authors.initials: A
authors.lastname: Cano
authors.affiliation: Psycho-oncology Unit, Department of Supportive Care - DISSPO, Institut Curie and University Paris Descartes, Psychopathology and Health Process Laboratory LPPS EA 4057, Paris, France. anne.bredart@curie.fr.
authors.forename: Anne
authors.initials: A
authors.lastname: Brédart
authors.affiliation: Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. n.aaronson@nki.nl.
authors.forename: Neil K
authors.initials: NK
authors.lastname: Aaronson
authors.affiliation: EA4275, Biostatistics, Pharmacoepidemiology and Subjective Measures in Health Sciences, University of Nantes, Nantes, France. jean-benoit.hardouin@univ-nantes.fr.|Unit of Methodology and Biostatistics - University Hospital of Nantes, Nantes, France. jean-benoit.hardouin@univ-nantes.fr.
authors.forename: Jean-Benoit
authors.initials: JB
authors.lastname: Hardouin
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000523:psychology* / Q000628:therapy; D005163:Factor Analysis, Statistical; D005239:Fear; D005260:Female; D005602:France; D006801:Humans; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010555:Personality Inventory; D011594:Psychometrics / Q000706:statistics & numerical data; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards*; D017741:Survivors / Q000523:psychology*; D014177:Translations; D016387:Women's Health