title: cfxA expression in oral clinical Capnocytophaga isolates.
abstract: Capnocytophaga spp. are commensal bacteria involved in oral and systemic diseases, with a variable susceptibility to beta-lactams. The cfxA gene expression level was assessed using quantitative RT-PCR, and reasons of the observed misexpression were discussed, as insertion of foreign genetic material, contributing to dissemination and evolution of antibiotic resistance genes.
authors.affiliation: Equipe de Microbiologie, EA 1254, Université de Rennes 1, Université Européenne de Bretagne, 2, avenue du Professeur Léon Bernard, 35043 Rennes, France.
authors.forename: Zohreh
authors.initials: Z
authors.lastname: Tamanai-Shacoori
authors.affiliation: Equipe de Microbiologie, EA 1254, Université de Rennes 1, Université Européenne de Bretagne, 2, avenue du Professeur Léon Bernard, 35043 Rennes, France.
authors.forename: Clarisse
authors.initials: C
authors.lastname: Monfort
authors.affiliation: Equipe de Microbiologie, EA 1254, Université de Rennes 1, Université Européenne de Bretagne, 2, avenue du Professeur Léon Bernard, 35043 Rennes, France.
authors.forename: Nolwenn
authors.initials: N
authors.lastname: Oliviero
authors.affiliation: Pole Biologie, Rennes Teaching Hospital, 2 rue Henri Le Guilloux, 35033 Rennes, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Gautier
authors.affiliation: Equipe de Microbiologie, EA 1254, Université de Rennes 1, Université Européenne de Bretagne, 2, avenue du Professeur Léon Bernard, 35043 Rennes, France; Pole Odontologie, Rennes Teaching Hospital, 2 rue Henri Le Guilloux, 35033 Rennes, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Bonnaure-Mallet
authors.affiliation: Equipe de Microbiologie, EA 1254, Université de Rennes 1, Université Européenne de Bretagne, 2, avenue du Professeur Léon Bernard, 35043 Rennes, France; Pole Biologie, Rennes Teaching Hospital, 2 rue Henri Le Guilloux, 35033 Rennes, France. Electronic address: anne.gougeon@univ-rennes1.fr.
authors.forename: Anne
authors.initials: A
authors.lastname: Jolivet-Gougeon
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002206:Capnocytophaga / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D020869:Gene Expression Profiling; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009061:Mouth Mucosa / Q000382:microbiology*; D016254:Mutagenesis, Insertional; D060888:Real-Time Polymerase Chain Reaction; D011995:Recombination, Genetic; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000235:genetics; D047090:beta-Lactams / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D001618:beta-Lactamases
keywords: Beta-lactamase; Capnocytophaga; Genetic environment; Mob; bla(CSP-1); cfxA