title: Quantitative Comparison of 2 Dual-Energy X-ray Absorptiometry Systems in Assessing Body Composition and Bone Mineral Measurements.
abstract: Dual-energy X-ray absorptiometry (DXA) is widely used in body composition measurement and evaluation. Because of its numerous applications, the probability of instrument discrepancies has increased dramatically. This study quantitatively compares 2 different DXA systems. In this study, 96 subjects (60 female and 36 male, aged 19-82 years) were recruited and scanned using a General Electric Lunar iDXA and a Hologic Discovery scanner. Four measurements (percent fat, total mass, bone mineral density [BMD], and bone mineral content [BMC]) were quantitatively compared in the whole body and in specific anatomic regions (arms, legs, trunk, android, gynoid, head, ribs, and pelvis). A simple linear regression of each measurement was performed to examine the correlation between the 2 systems. Percent fat, total mass, BMC, and BMD were highly correlated between the 2 DXA systems, with correlation r values greater than 0.854 for both the whole body and the individual anatomic regions except for BMC and BMD in ribs. The high correlation between the 2 DXA systems with systematic differences enabled development of calibration equations for extending the multisystem measurements to advanced quantitative analyses.
authors.affiliation: Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA, USA.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Xu
authors.affiliation: Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA, USA.
authors.forename: Hatim
authors.initials: H
authors.lastname: Chafi
authors.affiliation: Department of Experimental Statistics, Louisiana State University, Baton Rouge, LA, USA.
authors.forename: Beibei
authors.initials: B
authors.lastname: Guo
authors.affiliation: Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA.
authors.forename: Steven B
authors.initials: SB
authors.lastname: Heymsfield
authors.affiliation: Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA.
authors.forename: Kori B
authors.initials: KB
authors.lastname: Murray
authors.affiliation: Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA.
authors.forename: Jolene
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA, USA; Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA. Electronic address: gjia@lsu.edu.
authors.forename: Guang
authors.initials: G
authors.lastname: Jia
mesh_terms: D015502:Absorptiometry, Photon / Q000295:instrumentation*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition; D015519:Bone Density; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult
keywords: Dual-energy X-ray absorptiometry; bone mineral content; bone mineral density; percent fat; quantitative comparison; total mass