title: FEEDER VESSEL LASER PHOTOCOAGULATION FOR IDIOPATHIC, SUBFOVEAL POLYPOIDAL CHOROIDAL VASCULOPATHY NOT RESPONDING TO EITHER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY OR PHOTODYNAMIC THERAPY.
abstract: OBJECTIVE
  To describe the management of a subfoveal polypoidal choroidal vasculopathy case refractory to antiangiogenic treatment and to photodynamic therapy.
  
  
  METHODS
  Case report. A 65-year-old male patient presented with a diagnosis of exudative age-related macular degeneration of his left eye and unsuccessful response to eight antiangiogenic injections. Visual acuity was 20/33. Fluorescein angiography, spectral domain optical coherence tomography, and indocyanine green angiography confirmed the diagnosis of polypoidal choroidal vasculopathy. Two photodynamic therapy sessions along with two ranibizumab injections were performed, but no response was obtained. Identification and photocoagulation of the polyp feeder vessels was performed.
  
  
  RESULTS
  Polypoidal structures regressed, intraretinal and subretinal exudation resolved, and visual acuity was preserved with no adverse events.
  
  
  CONCLUSIONS
  Indocyanine green angiography-guided feeder vessel diode laser photocoagulation in selected cases of polypoidal choroidal vasculopathy may be considered an effective alternative therapy, especially in those refractory to both photodynamic therapy and antiangiogenic therapy.
authors.affiliation: *Institut de la Màcula i de la Retina, Barcelona, Spain; †Barcelona Macula Foundation: Research for Vision, Barcelona, Spain; and ‡Hospital Moisés Broggi, Barcelona, Spain.
authors.forename: Jordi
authors.initials: J
authors.lastname: Monés
authors.forename: Josep
authors.initials: J
authors.lastname: Badal
authors.forename: Marc
authors.initials: M
authors.lastname: Biarnés
mesh_terms: D000368:Aged; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D015862:Choroid Diseases / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D008297:Male; D000069579:Ranibizumab / Q000627:therapeutic use*; D012171:Retinal Vessels / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D020533:Angiogenesis Inhibitors; D000069579:Ranibizumab