title: A Systematic Review of Bovine Respiratory Disease Diagnosis Focused on Diagnostic Confirmation, Early Detection, and Prediction of Unfavorable Outcomes in Feedlot Cattle.
abstract: A large proportion of newly arrived feedlot cattle are affected with bovine respiratory disease (BRD). Economic losses could be reduced by accurate, early detection. This review evaluates the available literature regarding BRD confirmatory diagnostic tests, early detection methods, and modalities to estimate post-therapeutic prognosis or predict unfavorable or fatal outcomes. Scientific evidence promotes the use of haptoglobin to confirm BRD status. Feeding behavior, infrared thermography, and reticulorumen boluses are promising methods. Retrospective analyses of routinely collected treatment and cohort data can be used to identify cattle at risk of unfavorable outcome. Other methods have been reviewed but require further study.
authors.affiliation: Department of Production Animal Health, Faculty of Veterinary Medicine, University of Calgary, 3330 Hospital Drive Northwest, Calgary, Alberta T2N-4N1, Canada. Electronic address: bwolfger@ucalgary.ca.
authors.forename: Barbara
authors.initials: B
authors.lastname: Wolfger
authors.affiliation: Department of Production Animal Health, Faculty of Veterinary Medicine, University of Calgary, 3330 Hospital Drive Northwest, Calgary, Alberta T2N-4N1, Canada.
authors.forename: Edouard
authors.initials: E
authors.lastname: Timsit
authors.affiliation: Department of Clinical Sciences, Kansas State University, Mosier Hall Q 211, 1800 Denison Avenue, Manhattan, KS 66506, USA.
authors.forename: Brad J
authors.initials: BJ
authors.lastname: White
authors.affiliation: Department of Production Animal Health, Faculty of Veterinary Medicine, University of Calgary, 3330 Hospital Drive Northwest, Calgary, Alberta T2N-4N1, Canada.
authors.forename: Karin
authors.initials: K
authors.lastname: Orsel
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D015415:Biomarkers / Q000097:blood; D048090:Bovine Respiratory Disease Complex / Q000097:blood / Q000175:diagnosis* / Q000401:mortality / Q000517:prevention & control; D002417:Cattle; D042241:Early Diagnosis; D005247:Feeding Behavior; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D015415:Biomarkers
keywords: Bovine respiratory disease; Detection; Diagnostic test; Feedlot; Health monitoring system