title: Confocal foveated endomicroscope for the detection of esophageal carcinoma.
abstract: By mimicking the variable resolution of the human eye, a newly designed foveated endomicroscopic objective shows the potential to improve current endoscopic based techniques of identifying abnormal tissue in the esophagus and colon. The prototype miniature foveated objective is imaged with a confocal microscope to provide large field of view images combined with a high resolution central region to rapidly observe morphological structures associated with cancer development in a mouse model.
authors.affiliation: Rice University, Bioengineering Department, 6100 Main Street, Houston, TX 77005-1892, USA.
authors.forename: Adam
authors.initials: A
authors.lastname: Shadfan
authors.affiliation: Rice University, Bioengineering Department, 6100 Main Street, Houston, TX 77005-1892, USA.
authors.forename: Anne
authors.initials: A
authors.lastname: Hellebust
authors.affiliation: Rice University, Bioengineering Department, 6100 Main Street, Houston, TX 77005-1892, USA.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Richards-Kortum
authors.affiliation: Rice University, Bioengineering Department, 6100 Main Street, Houston, TX 77005-1892, USA.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Tkaczyk
keywords: (170.1790) Confocal microscopy; (170.2150) Endoscopic imaging; (170.3880) Medical and biological imaging; (170.3890) Medical optics instrumentation; (350.3950) Micro-optics