title: Melatonin: a potential intervention for hepatic steatosis.
abstract: Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a neuroendocrine hormone, which is primarily synthesized by the pineal gland in vertebrates. Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as circadian rhythm, energy metabolism, the reproductive system, the cardiovascular system, and the neuropsychiatric system. It also plays a role in disease by having anti-neoplastic and anti-osteoarthritic effects among others. Recently, research has focused on the roles of melatonin in oxidative stress, lipid metabolism, and hepatic steatosis and its potential therapeutic roles.
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
authors.forename: Hang
authors.initials: H
authors.lastname: Sun
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China.
authors.forename: Fang-fang
authors.initials: FF
authors.lastname: Huang
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, 200072, China. qushencn@hotmail.com.
authors.forename: Shen
authors.initials: S
authors.lastname: Qu
mesh_terms: D050154:Adiposity / Q000187:drug effects; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use; D005234:Fatty Liver / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007333:Insulin Resistance; D050356:Lipid Metabolism / Q000187:drug effects; D008550:Melatonin / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D008550:Melatonin