title: Persistent viral DNA detection in blood after primary herpes simplex 1 infection revealed by hepatitis with hemophagocytic syndrome.
abstract: We here report the case of a 52-year old man who presented hepatitis with hemophagocytic syndrome triggered by herpes simplex 1 (HSV-1) primary infection. A high-level viremia was observed, and HSV-1 DNA remained detectable in blood for a long time after patient's recovery.
authors.affiliation: Laboratoire de Virologie EA3610, Université Lille 2, Faculté de médecine, CHRU de, Lille, France.
authors.forename: E K
authors.initials: EK
authors.lastname: Alidjinou
authors.affiliation: Laboratoire de Virologie EA3610, Université Lille 2, Faculté de médecine, CHRU de, Lille, France.
authors.forename: A
authors.initials: A
authors.lastname: Dewilde
authors.affiliation: Service de Médecine Interne, Pôle de Médecine et Spécialités Médicales, CHRU de, Lille, France.
authors.forename: L
authors.initials: L
authors.lastname: Terriou
authors.affiliation: Laboratoire de Virologie EA3610, Université Lille 2, Faculté de médecine, CHRU de, Lille, France.
authors.forename: M
authors.initials: M
authors.lastname: Lazrek
authors.affiliation: Laboratoire de Virologie EA3610, Université Lille 2, Faculté de médecine, CHRU de, Lille, France.
authors.forename: I
authors.initials: I
authors.lastname: Engelmann
authors.affiliation: Laboratoire de Virologie EA3610, Université Lille 2, Faculté de médecine, CHRU de, Lille, France. Electronic address: didier.hober@chru-lille.fr.
authors.forename: D
authors.initials: D
authors.lastname: Hober
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D004279:DNA, Viral / Q000097:blood*; D005047:Etoposide / Q000627:therapeutic use; D006525:Hepatitis, Viral, Human / Q000097:blood / Q000188:drug therapy / Q000821:virology*; D006561:Herpes Simplex / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000821:virology*; D018259:Herpesvirus 1, Human / Q000187:drug effects / Q000235:genetics*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D051359:Lymphohistiocytosis, Hemophagocytic / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D019562:Viral Load / Q000187:drug effects
chemical_list: D004279:DNA, Viral; D016756:Immunoglobulins, Intravenous; D005047:Etoposide; D000212:Acyclovir