title: Optical Coherence Tomography for the Radiologist.
abstract: Optical coherence tomography is an imaging technique using low coherence light sources to produce high-resolution cross-sectional images. This article reviews pertinent anatomy and various pathologies causing optic atrophy (eg, compressive, infiltrating, demyelinating) versus optic nerve swelling (from increased intracranial pressure known as papilledema or other optic nerve intrinsic pathologies). On optical coherence tomography, optic atrophy is often associated with reduced average retinal nerve fiber layer thickness, whereas optic nerve swelling is usually associated with increased average retinal nerve fiber layer thickness.
authors.affiliation: MS Eye CARE, University Eye Institute, UHCO, University of Houston, 4901 Calhoun Street, Houston, TX 77204, USA; The Optic Nerve Center, Neuro-ophthalmology of Texas at the Medical Clinic of Houston, 1701 Sunset Blvd, Houston, TX 77005, USA.
authors.forename: Jade S
authors.initials: JS
authors.lastname: Schiffman
authors.affiliation: UHCO, University of Houston, 4901 Calhoun Street, Houston, TX 77204, USA.
authors.forename: Nimesh B
authors.initials: NB
authors.lastname: Patel
authors.affiliation: MS Eye CARE, University Eye Institute, UHCO, University of Houston, 4901 Calhoun Street, Houston, TX 77204, USA.
authors.forename: Roberto Alejandro
authors.initials: RA
authors.lastname: Cruz
authors.affiliation: MS Eye CARE, University Eye Institute, UHCO, University of Houston, 4901 Calhoun Street, Houston, TX 77204, USA; The Optic Nerve Center, Neuro-ophthalmology of Texas at the Medical Clinic of Houston, 1701 Sunset Blvd, Houston, TX 77005, USA. Electronic address: rtang@neuroeye.com.
authors.forename: Rosa A
authors.initials: RA
authors.lastname: Tang
mesh_terms: D005901:Glaucoma / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D059906:Neuroimaging / Q000379:methods*; D009900:Optic Nerve / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000473:pathology*; D012164:Retinal Diseases / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*
keywords: Circumpapillary retinal nerve fiber analysis; Ganglion cell layer; Macular imaging; Macular volume; Optic atrophy; Optic nerve imaging; Optic nerve swelling; Optical coherence tomography; Retinal nerve fiber bundle defect