title: The antioxidant activity and their major antioxidant compounds from Acanthopanax senticosus and A. koreanum.
abstract: The antioxidant activity and chlorogenic acid and caffeic acid contents were investigated from different parts of Acanthopanax senticosus and A. koreanum. Antioxidant activity was assessed by various in vitro assays such as DPPH, ABTS, FRAP, reducing power assays and ORAC, and the chlorogenic acid and caffeic acid were validated by HPLC chromatography. Among the various extracts, the fruit extracts of A. senticosus and A. koreanum exhibited strongest antioxidant activities including ABTS, FRAP, reducing power and ORAC, however, strongest DPPH radical scavenging activity was observed from the leaf extract of A. senticosus. In addition, the antioxidant activities of various extracts were correlated with total phenolic and proanthocyanidin contents. The major phenolic contents from various parts of these plants observed that leaf extract of A. senticosus expressed higher levels of chlorogenic acid (14.86 mg/dry weigh g) and caffeic acid (3.09 mg/dry weigh g) than other parts. Therefore, these results suggest that the leaf of A. senticosus may be an excellent natural source for functional foods and pharmaceutical agents, and the validated method was useful for the quality control of A. senticosus.
authors.affiliation: Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea. vvkyh@naver.com.
authors.forename: Young-Hyun
authors.initials: YH
authors.lastname: Kim
authors.affiliation: Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea. meanglae@naver.com.
authors.forename: Myoung Lae
authors.initials: ML
authors.lastname: Cho
authors.affiliation: Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea. danbekim22@nate.com.
authors.forename: Dan-Bi
authors.initials: DB
authors.lastname: Kim
authors.affiliation: Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea. cordelia162@hanmail.net.
authors.forename: Gi-Hae
authors.initials: GH
authors.lastname: Shin
authors.affiliation: Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea. tre98@hanmail.net.
authors.forename: Jin-Ha
authors.initials: JH
authors.lastname: Lee
authors.affiliation: National Institute of Biological Resources, Incheon 404-708, Korea. jongseoklee78@gmail.com.
authors.forename: Jong Seok
authors.initials: JS
authors.lastname: Lee
authors.affiliation: STR Biotech Co., LTD, Gangwon 200-160, Korea. lovastar@strbiotech.co.kr.
authors.forename: Sun-Ok
authors.initials: SO
authors.lastname: Park
authors.affiliation: STR Biotech Co., LTD, Gangwon 200-160, Korea. lsj@strbiotech.co.kr.
authors.forename: Sang-Jong
authors.initials: SJ
authors.lastname: Lee
authors.affiliation: Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01605, USA. hyunmu.shin@umassmed.edu.
authors.forename: Hyun Mu
authors.initials: HM
authors.lastname: Shin
authors.affiliation: Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea. loh99@kangwon.ac.kr.
authors.forename: Ok-Hwan
authors.initials: OH
authors.lastname: Lee
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification*; D028001:Eleutherococcus / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D010936:Plant Extracts
keywords: Acanthopanax senticosus; antioxidant activity; caffeic acid; chlorogenic acid; method validation