title: [Sub-threshold prostate-specific antigen levels after resection of metachronous pulmonary metastases].
abstract: Radical prostatectomy is a curative therapy for prostate cancer with a lifetime follow-up because there is a high risk of recurrence, especially in the first years of follow-up. In our case disseminated metachronous pulmonary metastases were detected by imaging 4 years after prostatectomy because of elevated levels of serum prostate-specific antigen (PSA). After complete resection of the thoracic metastases the PSA levels have remained below the detection threshold with a recurrence-free survival of 24 months. This case demonstrates that the resection of pulmonary metastases may also be useful for specific individual patients with prostate cancer.
authors.affiliation: Urologische Klinik, Klinikum der Universität München, Großhadern, Marchioninistraße 15, 81377, München, Deutschland. Annabel.spek@med.uni-muenchen.de.
authors.forename: A
authors.initials: A
authors.lastname: Spek
authors.affiliation: Institut für Pathologie, Klinikum der Universität München, München, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Faber
authors.affiliation: Urologische Klinik, Klinikum der Universität München, Großhadern, Marchioninistraße 15, 81377, München, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Stief
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D006801:Humans; D007610:Kallikreins / Q000097:blood*; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000601:surgery*; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology / Q000601:surgery*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; C549870:KLK3 protein, human; D007610:Kallikreins; D017430:Prostate-Specific Antigen
keywords: Prostatectomy; Pulmonary metastases; Relapse; Resection, metastases; Survival, progression-free