title: [Analysis of Electroencephalogram Sample Entropy Measurement in Frontal Association Cortex Based on Heroin-induced Conditioned Place Preference in Rats].
abstract: To explore the relationship between the drug-seeking behavior, motivation of conditioned place preference (CPP) rats and the frontal association cortex (FrA) electroencephalogram (EEG) sample entropy, we in this paper present our studies on the FrA EEG sample entropy of control group rats and CPP group rats, respectively. We invested different behavior in four situations of the rat activities, i. e. rats were staying in black chamber of videoed boxes, those staying in white chamber of videoed boxes, those shuttling between black-white chambers and those shuttling between white-black chambers. The experimental results showed that, compared with the control group rats, the FrA EEG sample entropy of CPP rats staying in black chamber of video box and shuttling between white-black chambers had no significant difference. However, sample entropy is significantly smaller (P < 0.01) when heroin-induced group rats stayed in white chamber of video box and shuttled between black-white chambers. Consequently, the drug-seeking behavior and motivation of CPP rats correlated closely with the EEG sample entropy changes.
authors.forename: Lei
authors.initials: L
authors.lastname: Huang
authors.forename: Qunwan
authors.initials: Q
authors.lastname: Pan
authors.forename: Zaiman
authors.initials: Z
authors.lastname: Zhu
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Chunfang
authors.initials: C
authors.lastname: Gao
authors.forename: Tian
authors.initials: T
authors.lastname: Li
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Xu
mesh_terms: D000818:Animals; D003213:Conditioning, Psychological / Q000187:drug effects*; D058999:Drug-Seeking Behavior; D004569:Electroencephalography; D019277:Entropy; D005625:Frontal Lobe / Q000187:drug effects / Q000502:physiology; D003932:Heroin / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D003932:Heroin