title: Frailty scoring in transcatheter aortic valve replacement patients.
abstract: Transcatheter aortic valve replacement (TAVR) is a less invasive treatment option for patients that are deemed too high a risk for surgical aortic valve replacement (SAVR). The aim of this review is to evaluate the frailty tools currently being used in patients referred for TAVR.
  
  
  
  Using a literature search involving database search engines from CINAHL, PubMed, SAGE publications and European Society of Cardiology conducted from 2010 to the present, a critical evaluation of studies dealing with frailty assessment in patients referred for TAVR/SAVR is discussed.
  
  
  
  Eight studies met the criteria using frailty assessment in TAVR/SAVR patients. In all reviewed studies the impact of frailty on clinical outcome has been proved. Different instruments for measurements of frailty were used that have not been robustly evaluated. Frailty was defined differently and results may not be comparable. All reviewed studies used different cutoffs and scales and some a composite scoring system, although validity was limited.
  
  
  
  For frailty assessment implementation of validated standardized test protocols based on well-established assessment tools, covering all domains of frailty among TAVR centers is crucial for patient selection. Secondly, validated cutoffs and scoring systems are essential.
authors.affiliation: Department of Cardiology, Paracelsus Medical University, Salzburger Landeskliniken, Salzburg, Austria.
authors.forename: Lynne
authors.initials: L
authors.lastname: Hinterbuchner
authors.affiliation: Department of Cardiology, Paracelsus Medical University, Salzburger Landeskliniken, Salzburg, Austria.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Strohmer
authors.affiliation: Department of Cardiology, Paracelsus Medical University, Salzburger Landeskliniken, Salzburg, Austria.
authors.forename: Matthias
authors.initials: M
authors.lastname: Hammerer
authors.affiliation: Department of Cardiology, Paracelsus Medical University, Salzburger Landeskliniken, Salzburg, Austria.
authors.forename: Erika
authors.initials: E
authors.lastname: Prinz
authors.affiliation: Department of Cardiology, Paracelsus Medical University, Salzburger Landeskliniken, Salzburg, Austria.
authors.forename: Uta C
authors.initials: UC
authors.lastname: Hoppe
authors.affiliation: Department of Cardiology, Paracelsus Medical University, Salzburger Landeskliniken, Salzburg, Austria c.schernthaner@salk.at.
authors.forename: Christiana
authors.initials: C
authors.lastname: Schernthaner
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D016330:Frail Elderly / Q000706:statistics & numerical data*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D012307:Risk Factors; D012720:Severity of Illness Index; D015996:Survival Rate; D065467:Transcatheter Aortic Valve Replacement / Q000379:methods*; D016896:Treatment Outcome
keywords: Frailty; aortic stenosis; transcatheter aortic valve replacement