title: Congenital Chikungunya--A Cause of Neonatal Hyperpigmentation.
abstract: A 12-day-old neonate presented with ill-defined dark pigmentation over the centrofacial area with flagellate pigmentation on the trunk and patchy pigmentation on the extremities. The mother had a history of fever starting a week before delivery and continuing for 3 days in the postpartum period. Together these led to consideration of a possible diagnosis of congenital chikungunya, which was confirmed according to the immunoglobulin M antibodies to chikungunya in the mother and child. The rare occurrence of cutaneous pigmentation was the only clue to the retrospective diagnosis of neonatal chikungunya. Chikungunya is an emerging viral disease that can be transmitted maternally during pregnancy and in the peripartum period. It can be added to the list of viral infections that can lead to fetal demise or, when present during labor and delivery, can cause neonatal disease with cutaneous signs.
authors.affiliation: Department of Dermatology, K J Somaiya Medical College and Research Centre, Sion, Mumbai, Maharashtra, India.
authors.forename: Resham
authors.initials: R
authors.lastname: Vasani
authors.affiliation: Department of Pediatrics, K J Somaiya Medical College, Sion, Mumbai, Maharashtra, India.
authors.forename: Sujata
authors.initials: S
authors.lastname: Kanhere
authors.affiliation: Department of Pediatrics, K J Somaiya Medical College, Sion, Mumbai, Maharashtra, India.
authors.forename: Kushagra
authors.initials: K
authors.lastname: Chaudhari
authors.affiliation: Department of Pediatrics, K J Somaiya Medical College, Sion, Mumbai, Maharashtra, India.
authors.forename: Varsha
authors.initials: V
authors.lastname: Phadke
authors.affiliation: Department of Pediatrics, K J Somaiya Medical College, Sion, Mumbai, Maharashtra, India.
authors.forename: Priyashree
authors.initials: P
authors.lastname: Mukherjee
authors.affiliation: Department of Pediatrics, K J Somaiya Medical College, Sion, Mumbai, Maharashtra, India.
authors.forename: Swati
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Department of Pediatrics, K J Somaiya Medical College, Sion, Mumbai, Maharashtra, India.
authors.forename: Chetan
authors.initials: C
authors.lastname: Kasliwal
authors.affiliation: Department of Dermatology, K J Somaiya Medical College and Research Centre, Sion, Mumbai, Maharashtra, India.
authors.forename: Shital
authors.initials: S
authors.lastname: Poojary
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D065632:Chikungunya Fever / Q000150:complications / Q000151:congenital*; D002646:Chikungunya virus / Q000276:immunology; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology*; D007075:Immunoglobulin M / Q000032:analysis; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis*; D018445:Infectious Disease Transmission, Vertical; D008297:Male
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M