title: Thrombus aspiration during primary percutaneous coronary intervention associated with reduced platelet activation.
abstract: OBJECTIVE
  To determine the effect of thrombectomy on platelet function in patients undergoing primary percutaneous coronary intervention (PPCI) for ST segment elevation myocardial infarction (STEMI).
  
  
  METHODS
  This retrospective study included 413 consecutive STEMI patients who underwent PPCI between March 2012 and September 2013 at Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey that were assigned to the thrombus aspiration (TA) group or the non-TA group. Platelet count and mean platelet volume (MPV) were obtained at baseline and 24 hours (h), 48 h, and 72 h post PPCI.
  
  
  RESULTS
  Baseline MPV was similar in both groups, whereas the baseline platelet count was higher in the TA group (p=0.42 and p=0.002). The platelet count was higher in the TA group 24 h post PPCI (p=0.02), but was similar in both groups 48 h and 72 h post PPCI (p=0.18 and p=0.07). The MPV 48 h and 72 h post PPCI was higher in the non-TA group than in the TA group (8.4 ± 1.3 fL versus 8.7 ± 1.6 fL [p=0.04] and 8.5 ± 1.1 fL versus 8.9 ± 1.5 fL [p=0.04]).
  
  
  CONCLUSIONS
  Thrombectomy reduced platelet activity via removal of thrombi from the coronary arteries in patients undergoing PPCI for STEMI.
authors.affiliation: Department of Cardiology, Kartal Kosuyolu High Specialty Education and Research Hospital, Istanbul, Turkey. E-mail. sahinm78@yahoo.com.
authors.forename: Muslum
authors.initials: M
authors.lastname: Sahin
authors.forename: Goksel
authors.initials: G
authors.lastname: Acar
authors.forename: Mehmet E
authors.initials: ME
authors.lastname: Kalkan
authors.forename: Rezzan D
authors.initials: RD
authors.lastname: Acar
authors.forename: Alev
authors.initials: A
authors.lastname: Kilicgedik
authors.forename: Burak
authors.initials: B
authors.lastname: Teymen
authors.forename: Ugur
authors.initials: U
authors.lastname: Arslantas
authors.forename: Cevat
authors.initials: C
authors.lastname: Kirma
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000601:surgery*; D062645:Percutaneous Coronary Intervention; D015539:Platelet Activation; D012189:Retrospective Studies; D017131:Thrombectomy