title: Skull base metastasis from papillary thyroid carcinoma: a report of three cases.
abstract: Skull base metastasis from differentiated thyroid carcinoma, including papillary and follicular thyroid carcinoma, is a rare manifestation. Herein, we present three cases of skull base metastasis of papillary thyroid carcinoma. The mean age of the patients was 68.6 (65-74) years, and the mean interval between initial diagnosis and skull base metastasis was 56.3 (28-89) months. Cranial nerve palsies were seen in all patients. Intensity modulated radiation therapy to deliver 6,000-6,600 cGy to the skull base metastasis was given to all patients, in addition to partial resection in one patient. At the time of last follow-up, all skull base metastases were well controlled.
authors.affiliation: Radiation Oncology, King Fahad Medical City, Riyadh, Saudi Arabia.
authors.forename: Mutahir A
authors.initials: MA
authors.lastname: Tunio
authors.affiliation: Radiation Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh, Saudi Arabia.
authors.forename: Mushabbab
authors.initials: M
authors.lastname: Al Asiri
authors.affiliation: Department of Otolaryngology -Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Khalid Hussain
authors.initials: KH
authors.lastname: Al-Qahtani
authors.affiliation: Department of Histopathology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh, Saudi Arabia.
authors.forename: Sadiq
authors.initials: S
authors.lastname: Aldandan
authors.affiliation: Radiation Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh, Saudi Arabia.
authors.forename: Khalid
authors.initials: K
authors.lastname: Riaz
authors.affiliation: Radiation Oncology, National Cancer Institute, Cairo University, Cairo, Egypt.
authors.forename: Yasser
authors.initials: Y
authors.lastname: Bayoumi
keywords: papillary thyroid carcinoma; skull base metastasis; treatment