title: Association of CYP2J2 gene polymorphisms with ischemic stroke.
abstract: OBJECTIVE
  The present study aims to investigate the relationship between CYP2J2 gene polymorphisms and ischemic stroke (IS) in a Chinese Han population.
  
  
  METHODS
  We performed a case-control study including 300 stroke patients and 300 healthy control subjects to compare the distribution of genetic polymorphism G-50T in CYP2J2 gene.
  
  
  RESULTS
  We found GT genotype of G-50T in CYP2J2 gene was associated with the risk for IS (13.7% vs. 7.7%, P = 0.037). After adjustment of confounders, the difference remains significant (OR = 1.890, 95% CI: 1.042-3.011).
  
  
  CONCLUSIONS
  CYP2J2 gene polymorphism might increase the risk of stroke in Chinese population.
authors.affiliation: Department of Neurology, First Affiliated Hospital of Xinxiang Medical University Weihui 453100, Henan, P. R. China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
authors.affiliation: Department of Neurology, First Affiliated Hospital of Xinxiang Medical University Weihui 453100, Henan, P. R. China.
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Zhao
authors.affiliation: Department of Neurosurgery, First Affiliated Hospital of Xinxiang Medical University Weihui 453100, Henan, P. R. China.
authors.forename: Peng-Ju
authors.initials: PJ
authors.lastname: Ma
authors.affiliation: Department of Neurology, First Affiliated Hospital of Xinxiang Medical University Weihui 453100, Henan, P. R. China.
authors.forename: Lin-Lin
authors.initials: LL
authors.lastname: Su
authors.affiliation: Department of Neurology, First Affiliated Hospital of Xinxiang Medical University Weihui 453100, Henan, P. R. China.
authors.forename: Sheng-Bo
authors.initials: SB
authors.lastname: Tao
authors.affiliation: Department of Neurology, First Affiliated Hospital of Xinxiang Medical University Weihui 453100, Henan, P. R. China.
authors.forename: Si-Bei
authors.initials: SB
authors.lastname: Ji
keywords: CYP2J2 gene; Ischemic stroke; single nucleotide polymorphism