title: Influence of Dietary Ascorbic Acid on the Immune Responses of Juvenile Korean Rockfish Sebastes schlegelii.
abstract: Juvenile Korean Rockfish Sebastes schlegelii (length, 13.6 ± 1.4 cm [mean ± SD]; weight, 53.6 ± 4.2 g) were fed twice daily with diets containing varying levels of ascorbic acid (0, 50, 100, 200, and 400 mg/kg) for 4 weeks. Significant increases in daily weight and length occurred in fish fed more than 50 mg/kg ascorbic acid. The lysozyme activity of fish fed diets containing ascorbic acid was considerably increased in rockfish plasma at 400 mg/kg ascorbic acid and in kidney at over 50 mg/kg ascorbic acid. Total plasma immunoglobulin M (IgM) levels were markedly elevated in fish fed 400 mg/kg ascorbic acid. The results suggest that dietary ascorbic acid supplementation in juvenile rockfish can induce a significant increase in growth and in immunological features such as lysozyme activity and plasma IgM levels.
authors.affiliation: a Department of Aquatic Life Medicine , Pukyong National University , Busan , 608-737 , South Korea.
authors.forename: Jun-Hwan
authors.initials: JH
authors.lastname: Kim
authors.forename: Ju-Chan
authors.initials: JC
authors.lastname: Kang
mesh_terms: D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology*; D004032:Diet / Q000662:veterinary; D019587:Dietary Supplements; D007075:Immunoglobulin M / Q000097:blood / Q000378:metabolism*; D009113:Muramidase / Q000097:blood / Q000378:metabolism; D010473:Perciformes / Q000276:immunology*
chemical_list: D007075:Immunoglobulin M; D009113:Muramidase; D001205:Ascorbic Acid