title: Highly efficient and compatible shampoo for use after hair transplant.
abstract: BACKGROUND
  Sensitive or hyperreactive skin is a common condition defined by prickling, burning, pain, and pruritus. Although this skin problem was initially described on the face, the scalp is often affected. A sensitive scalp can react with irritation to harsh surfactants or other additives which are often present in shampoos. For this reason, we developed a new rinse-off hypertolerant shampoo specifically designed for the hypersensitive and problematic scalp.
  
  
  METHODS
  The shampoo formulation is based on an extremely mild surfactant system and contains bisabolol, an anti-irritant and anti-inflammatory ingredient of chamomile. The shampoo is free of additives such as perfumes, silicones, colorants, parabens, paraffins, and betaine. Since skin can remain in a hyperreactive state after wounding, the status after hair transplantation was chosen as a model system to test the shampoo. Scalp condition and compatibility of each volunteer were analyzed by a plastic surgeon directly after hair transplant and after stitch removal. The plastic surgeons also rated whether they would recommend the further use of the test shampoo. Additionally, volunteers completed a self-assessment questionnaire.
  
  
  RESULTS
  Following hair transplantation, regular use of the shampoo resulted in a significant reduction in the extent of scabbing and erythema. This was confirmed by dermatological scalp examinations performed by the plastic surgeon as well as in volunteers' self-assessments. The plastic surgeon highly recommended the further use of the test shampoo after hair transplant to all study participants.
  
  
  CONCLUSIONS
  Application of the test shampoo demonstrated excellent skin compatibility and product efficacy after hair transplant. The test shampoo significantly reduced the extent of scabs and erythema. Therefore, the shampoo is ideally suited for use after hair transplantation and for the treatment of sensitive scalp. The excellent skin compatibility is because of the mild surfactant system, the calming ingredient bisabolol, and the absence of potentially irritating ingredients.
authors.affiliation: Research and Development, Beiersdorf AG, Hamburg, Germany.
authors.forename: Dorothea
authors.initials: D
authors.lastname: Schweiger
authors.affiliation: Research and Development, Beiersdorf AG, Hamburg, Germany.
authors.forename: Andrea M
authors.initials: AM
authors.lastname: Schoelermann
authors.affiliation: Research and Development, Beiersdorf AG, Hamburg, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Filbry
authors.affiliation: Research and Development, Beiersdorf AG, Hamburg, Germany.
authors.forename: Tina
authors.initials: T
authors.lastname: Hamann
authors.affiliation: Moser Medical, Clinics for Aesthetic Plastic Surgery, Vienna, Austria.
authors.forename: Claudia
authors.initials: C
authors.lastname: Moser
authors.affiliation: Research and Development, Beiersdorf AG, Hamburg, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Rippke
keywords: bisabolol; hair transplant; scalp; sensitive; shampoo