title: Exploration of Dimethylzinc-Mediated Radical Reactions.
abstract: In this account, our studies on radical reactions that are promoted by dimethylzinc and air are described. Advantages of this reagent and differences from conventional radical initiators, such as triethylborane, are discussed.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan. yamak@pharm.kyoto-u.ac.jp.
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Yamada
authors.affiliation: Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyoto, Japan. ktomioka@dwc.doshisha.ac.jp.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tomioka
mesh_terms: D001880:Boranes / Q000138:chemical synthesis* / Q000737:chemistry; D005609:Free Radicals / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D001880:Boranes; D005609:Free Radicals; D009942:Organometallic Compounds; D015032:Zinc; C079756:triethylborane
keywords: C(sp3)-H bond functionalization; carbon-carbon bond formation; dimethylzinc; radical reactions; umpolung