title: Zinc and copper levels are not correlated with angiographically-defined coronary artery disease in sudanese patients.
abstract: We investigated zinc and copper levels in angiographically defined obstructive coronary artery disease (CAD) in patients undergoing elective coronary angiography in El-Shaab Hospital, Sudan. We performed a cross-sectional study. One hundred forty-two patients were enrolled. Sociodemographic and medical characteristics were collected using a questionnaire. Glucose, lipid, zinc, and copper levels were measured. Out of 142 patients, 102 (71.8%) had CAD and 40 (28.2%) had patent coronary arteries. There were no significant differences in median (interquartile range) zinc [118.5 (97.2-151.0) vs. 130.0 (106.0-174.0) μg/ml, P = 0.120] and copper [150.6 (125.0-183.0) vs. 158 (132.0-180.0) μg/mL, P = 0.478] levels between patients with CAD and those with patent coronary arteries. In linear regression analysis, there were no associations between CAD and zinc and copper levels. The current study failed to show any significant association between CAD and zinc and copper levels.
authors.affiliation: Faculty of Medicine, Alneelain University Khartoum, Sudan.
authors.forename: Mohamed F
authors.initials: MF
authors.lastname: Lutfi
authors.affiliation: Faculty of Medicine, Alneelain University Khartoum, Sudan.
authors.forename: Ramaze F
authors.initials: RF
authors.lastname: Elhakeem
authors.affiliation: Faculty of Laboratory Science, Sudan International University Khartoum, Sudan.
authors.forename: Raga S
authors.initials: RS
authors.lastname: Khogaly
authors.affiliation: Faculty of Laboratory Science, Alneelain University Khartoum, Sudan.
authors.forename: Abdelkarim A
authors.initials: AA
authors.lastname: Abdrabo
authors.affiliation: Faculty of Laboratory Science, Alneelain University Khartoum, Sudan.
authors.forename: Ahmed B
authors.initials: AB
authors.lastname: Ali
authors.affiliation: Faculty of Medicine, Alneelain University Khartoum, Sudan.
authors.forename: Gasim I
authors.initials: GI
authors.lastname: Gasim
authors.affiliation: Faculty of Medicine, University of Khartoum Khartoum, Sudan.
authors.forename: Ishag
authors.initials: I
authors.lastname: Adam
keywords: angina; angiography; copper; coronary artery; zinc