title: [Effect of hepatitis on surgical treatment and prognosis of colorectal liver metastasis].
abstract: OBJECTIVE
  To evaluate the effect of hepatitis on surgical treatment and prognosis of colorectal liver metastasis(CRLM).
  
  
  METHODS
  A retrospective study of medical records of all the patients undergoing operation with colorectal liver metastasis in Peking University Hepatobiliary pancreatic Surgery Ward I from November 2007 to January 2013 was conducted. A total of 175 patients were eligible and divided into two groups: with hepatitis (n=16) or without hepatitis (n=159).
  
  
  RESULTS
  Preoperative liver function was similar in these two groups. There were no significant differences in preoperative serum albumin, total bilirubin and prothrombin time between two groups (all P>0.05), except for lower blood platelet in hepatitis group after operation. Major hepatectomy was performed in 37.5% (6/16) and 22.0% (15/159) of two groups respectively (P>0.05). There were also no significant differences in operation time, blood loss, surgical complications and drainage volume (all P>0.05). The median overall survival time was 46 months in hepatitis group and 33 months in non-hepatitis group, and the median disease free time was 8 months in hepatitis group and 10 months in non-hepatitis group (all P>0.05).
  
  
  CONCLUSIONS
  CRLM patients concomitant with hepatitis have adequate liver reserve function for major hepatic resection and have similar prognosis of patients without hepatitis.
authors.affiliation: Key laboratory of Carcinogenesis and Translational Research(Ministry of Education), Hepatobiliary pancreatic Surgery Ward I, Peking University Cancer Hospital and Institute, Beijing 100142, China. xingbaocai88@sina.com.
authors.forename: Ming
authors.initials: M
authors.lastname: Liu
authors.forename: Kun
authors.initials: K
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Sun
authors.forename: Quan
authors.initials: Q
authors.lastname: Bao
authors.forename: Hongwei
authors.initials: H
authors.lastname: Wang
authors.forename: Kemin
authors.initials: K
authors.lastname: Jin
authors.forename: Baocai
authors.initials: B
authors.lastname: Xing
mesh_terms: D015179:Colorectal Neoplasms; D004322:Drainage; D006498:Hepatectomy; D006505:Hepatitis; D006801:Humans; D008113:Liver Neoplasms; D061646:Operative Time; D011379:Prognosis; D012189:Retrospective Studies