title: Experimental Study of the Pathogenicity of Pasteurella multocida Capsular Type B in Rabbits.
abstract: The increased frequency of isolation of Pasteurella multocida capsular type B from rabbitries in north-western India prompted this investigation into the role of this organism in inducing disease in rabbits. Ten rabbits were divided into two groups of five animals. Group I rabbits were infected intranasally (IN) with 1 ml of inoculum containing 2 × 10(5) colony forming units/ml, while rabbits in group II were given 1 ml phosphate buffered saline IN. The rabbits in group I developed respiratory distress, increased rectal temperature and severe dyspnoea, with death occurring 24-48 h post infection. The main pathological findings were severe congestion and haemorrhage in the trachea, fibrinopurulent pneumonia, bacteraemia and septicaemia. The nasal secretions of all group I animals contained P. multocida. These observations indicate that in addition to P. multocida capsular types A and D, P. multocida capsular type B can also be highly pathogenic for rabbits.
authors.affiliation: Department of Veterinary Microbiology, Dr. G. C. Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.
authors.forename: S
authors.initials: S
authors.lastname: Katoch
authors.affiliation: Department of Veterinary Microbiology, Dr. G. C. Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.
authors.forename: L
authors.initials: L
authors.lastname: Verma
authors.affiliation: Department of Veterinary Microbiology, Dr. G. C. Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.
authors.forename: M
authors.initials: M
authors.lastname: Sharma
authors.affiliation: Department of Veterinary Pathology, Dr. G. C. Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.
authors.forename: R K
authors.initials: RK
authors.lastname: Asrani
authors.affiliation: Department of Veterinary Microbiology, Dr. G. C. Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.
authors.forename: S
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Department of Veterinary Microbiology, Dr. G. C. Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India.
authors.forename: R
authors.initials: R
authors.lastname: Chahota
authors.affiliation: Department of Veterinary Microbiology, Dr. G. C. Negi College of Veterinary and Animal Sciences, Palampur, Himachal Pradesh, India. Electronic address: sverma8@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Verma
mesh_terms: D000818:Animals; D010326:Pasteurella Infections / Q000235:genetics / Q000382:microbiology* / Q000473:pathology*; D016979:Pasteurella multocida / Q000235:genetics / Q000472:pathogenicity*; D011817:Rabbits; D014774:Virulence
keywords: Pasteurella multocida capsular type B; pathogenicity; rabbit