title: Click modification of diazido acridine intercalators: a versatile route towards decorated DNA nanostructures.
abstract: Diazido derivatives of 3,6-diamino acridine (proflavine) intercalate into DNA and undergo functionalization through click chemistry to form 1D nanostructures with redox active, conductive nanowire, and fluorescent properties. This two-step approach, intercalation followed by click modification allows for the controlled decoration of DNA nanostructures.
authors.affiliation: School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK).
authors.forename: Shahrbanou
authors.initials: S
authors.lastname: Moradpour Hafshejani
authors.affiliation: School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK).
authors.forename: Scott M D
authors.initials: SM
authors.lastname: Watson
authors.affiliation: School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK). eimer.tuite@ncl.ac.uk.
authors.forename: Eimer M
authors.initials: EM
authors.lastname: Tuite
authors.affiliation: School of Chemistry, Bedson Building, Newcastle University, Newcastle upon Tyne, NE1 7RU (UK). andrew.pike@ncl.ac.uk.
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Pike
mesh_terms: D000166:Acridines / Q000737:chemistry*; D057930:Click Chemistry; D004247:DNA / Q000737:chemistry*; D007364:Intercalating Agents / Q000737:chemistry*; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D000166:Acridines; D007364:Intercalating Agents; D004247:DNA
keywords: DNA; click chemistry; nanomaterials; scanning probe microscopy