title: Posterior reversible leukoencephalopathy syndrome with spinal cord involvement in a 9-year-old girl.
abstract: We report the youngest pediatric case of posterior reversible leukoencephalopathy syndrome confined to brainstem and spinal cord. At presentation bicytopenia, renal derangement, visual disturbances, magnetic resonance imaging findings, increased protein content, IgG index and cell count in the cerebrospinal fluid led us to extensive search for myelitis. She received a short course of steroid treatment. The final diagnosis was hypertension due to reflux nephropathy. Severe hypertension that exceeds the range of autoregulation in anterior spinal territory may result in spinal posterior reversible leukoencephalopathy syndrome. Clinicians should be aware of spinal posterior reversible leukoencephalopathy syndrome when cases have extensive lesions in the brainstem and spinal cord with none or minimal clinical findings, so called "clinical radiologic dissociation".
authors.affiliation: Dokuz Eylül University, School of Medicine, Department of Pediatrics, Division of Pediatric Neurology, İzmir, Turkey. Electronic address: ulyis@yahoo.com.
authors.forename: Uluç
authors.initials: U
authors.lastname: Yiş
authors.affiliation: Dokuz Eylül University, School of Medicine, Department of Pediatrics, Division of Pediatric Neurology, İzmir, Turkey.
authors.forename: Pakize
authors.initials: P
authors.lastname: Karaoğlu
authors.affiliation: Dokuz Eylül University, School of Medicine, Department of Pediatrics, Division of Pediatric Neurology, İzmir, Turkey.
authors.forename: Semra Hız
authors.initials: SH
authors.lastname: Kurul
authors.affiliation: Dokuz Eylül University, School of Medicine, Department of Pediatrics, Division of Pediatric Nephrology, İzmir, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Soylu
authors.affiliation: Dokuz Eylül University, School of Medicine, Department of Radiology, Division of Pediatric Radiology, İzmir, Turkey.
authors.forename: Handan
authors.initials: H
authors.lastname: Çakmakçi
authors.affiliation: Dokuz Eylül University, School of Medicine, Department of Pediatrics, Division of Pediatric Nephrology, İzmir, Turkey.
authors.forename: Salih
authors.initials: S
authors.lastname: Kavukçu
mesh_terms: D001933:Brain Stem / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D054038:Posterior Leukoencephalopathy Syndrome / Q000188:drug therapy / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology*; D016896:Treatment Outcome
keywords: Child; Myelitis; Posterior reversible leukoencephalopathy syndrome; Spinal cord