title: Angiokeratomas Scroti Associated with Angiokeratomas of the Eyelids: Coincidence or One Entity? A Case Report and Review of the Literature.
abstract: We describe a unique patient with multiple angiokeratomas on both upper eyelids and on the scrotum. We review the literature and discuss the pathogenetic relationship. Angiokeratomas are described as vascular lesions, which are defined histologically as one or several dilated blood vessel(s) covered by a keratotic layer. They are usually divided into 5 groups: angiokeratoma of Mibelli, Fordyce's angiokeratoma, angiokeratoma corporis diffusum, angiokeratoma circumscriptum naeviforme and solitary angiokeratoma. Angiokeratomas of the eyelid are a very rare finding in the literature, whereas they appear more frequently on the scrotum. The aim of this report is to present a new case of angiokeratomas on the eyelids combined with angiokeratomas of the scrotum. The clinical manifestation and the aetiology of angiokeratomas vary among the subtypes. While the pathogenesis in Fordyce's angiokeratoma seems to be based on increased venous pressure, the cause of angiokeratomas of the eyelids remains to be discussed.
authors.affiliation: Department of Dermatology, University Hospital of Basel, Basel, Switzerland.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Buehler
authors.forename: Peter
authors.initials: P
authors.lastname: Itin
mesh_terms: D000328:Adult; D000794:Angiokeratoma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005142:Eyelid Neoplasms; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary; D012611:Scrotum; D012878:Skin Neoplasms / Q000175:diagnosis*