title: [Necrotizing tracheobronchial aspergillosis in an immunosuppressed patient. Report of one case].
abstract: Necrotizing tracheobronchitis due to Aspergillus spp is a rare form of invasive aspergillosis. This infection is limited to or predominant in the bronchial tree. The clinical evolution is gradual: from mild non-specific manifestations of acute tracheobronchitis to severe acute respiratory insufficiency determined by a bronchial obstruction syndrome. We report a 38 years old female with systemic lupus erythematosus treated with methylprednisolone and cyclophosphamide. She developed an invasive aspergillosis, severe respiratory failure with predominant tracheobronchial damage and upper respiratory complications.
authors.forename: Max H
authors.initials: MH
authors.lastname: Andresen
authors.forename: Carmen Paz
authors.initials: CP
authors.lastname: Venegas
authors.forename: Claudia
authors.initials: C
authors.lastname: Vega
authors.forename: Carlos
authors.initials: C
authors.lastname: Aravena
authors.forename: Max V
authors.initials: MV
authors.lastname: Andresen
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications*; D001991:Bronchitis / Q000382:microbiology*; D001999:Bronchoscopy; D017809:Fatal Outcome; D005260:Female; D005385:Fingers / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D009336:Necrosis; D012772:Shock, Septic / Q000150:complications; D014034:Toes / Q000473:pathology; D014136:Tracheitis / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents