title: Interpersonal Problems, Mindfulness, and Therapy Outcome in an Acceptance-Based Behavior Therapy for Generalized Anxiety Disorder.
abstract: OBJECTIVE
  To better understand the role interpersonal problems play in response to two treatments for generalized anxiety disorder (GAD); an acceptance-based behavior therapy (ABBT) and applied relaxation (AR), and to examine how the development of mindfulness may be related to change in interpersonal problems over treatment and at follow-up.
  
  
  METHODS
  Eighty-one individuals diagnosed with GAD (65.4% female, 80.2% identified as white, average age 32.92) were randomized to receive 16 sessions of either ABBT or AR. GAD severity, interpersonal problems, and mindfulness were measured at pre-treatment, post-treatment, 6-month follow-up, and 12-month follow-up.
  
  
  RESULTS
  Mixed effect regression models did not reveal any significant effects of pre-treatment interpersonal problems on GAD severity over treatment. After controlling for post-treatment GAD severity, remaining post-treatment interpersonal problems predicted 6- but not 12-month GAD severity. Participants in both conditions experienced a large decrease in interpersonal problems over treatment. Increases in mindfulness over treatment and through follow-up were associated with decreases in interpersonal problems, even when accounting for reductions in overall GAD severity.
  
  
  CONCLUSIONS
  Interpersonal problems may be an important target of treatment in GAD, even if pre-treatment interpersonal problems are not predictive of outcome. Developing mindfulness in individuals with GAD may help ameliorate interpersonal difficulties among this population.
authors.affiliation: a Department of Psychology , Suffolk University , 41 Temple Street, Boston , MA 02114 , USA.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Millstein
authors.affiliation: a Department of Psychology , Suffolk University , 41 Temple Street, Boston , MA 02114 , USA.
authors.forename: Susan M
authors.initials: SM
authors.lastname: Orsillo
authors.affiliation: b Department of Psychology , University of Massachusetts Boston , 100 Morrissey Blvd, Boston , MA 02125 , USA.
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Hayes-Skelton
authors.affiliation: b Department of Psychology , University of Massachusetts Boston , 100 Morrissey Blvd, Boston , MA 02125 , USA.
authors.forename: Lizabeth
authors.initials: L
authors.lastname: Roemer
mesh_terms: D064869:Acceptance and Commitment Therapy; D000328:Adult; D001008:Anxiety Disorders / Q000628:therapy*; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D064866:Mindfulness; D012064:Relaxation Therapy; D016896:Treatment Outcome; D055815:Young Adult
keywords: acceptance-based treatment; applied relaxation; generalized anxiety disorder; interpersonal problems; mindfulness