title: Cushing's syndrome in pregnancy. Laparoscopic adrenalectomy during pregnancy: the mainstay treatment.
abstract: BACKGROUND
  Cushing's syndrome (CS) is a rare disease in pregnancy and its differential diagnosis is complicated. It is usually confused with complicated pregnancy cases, such us preeclampsia and gestational diabetes. This usually leads to a delayed diagnosis and is also associated with severe materno-foetal complications.
  
  
  OBJECTIVE
  We present a case of a pregnant woman in her third trimester of pregnancy with CS secondary to an adrenal adenoma without response to medical treatment who underwent laparoscopic adrenalectomy without complications.
  
  
  CONCLUSIONS
  Most authors consider adrenalectomy as the first-choice treatment, since it presents higher rate of successful pregnancies. However, previously published cases did not reflect this stance. These publications prefer to maintain medical treatment, allowing pregnancy to go to term and delaying adrenalectomy after childbirth. We consider that experience in laparoscopic surgery, obstetric knowledge and resources now available, all offer sufficient guarantees to carry out the laparoscopic procedure to treat CS in pregnancy even in the third trimester. Laparoscopic adrenalectomy for CS in pregnancy is a safe and efficacious procedure allowing stopping the disease and curbing the dreadful consequences it may have for both mother and foetus.
authors.affiliation: General and Digestive Surgery Department, Universitary Hospital Doctor Peset, Avda. Gaspar Aguilar 90, 46017, Valencia, Spain. charobenlloch@hotmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Martínez García
authors.affiliation: General and Digestive Surgery Department, Universitary Hospital Doctor Peset, Avda. Gaspar Aguilar 90, 46017, Valencia, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Martínez Pérez
authors.affiliation: General and Digestive Surgery Department, Universitary Hospital Doctor Peset, Avda. Gaspar Aguilar 90, 46017, Valencia, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Domingo del Pozo
authors.affiliation: General and Digestive Surgery Department, Universitary Hospital Doctor Peset, Avda. Gaspar Aguilar 90, 46017, Valencia, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Sospedra Ferrer
mesh_terms: D000315:Adrenalectomy; D000328:Adult; D003480:Cushing Syndrome / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology / Q000601:surgery*; D011263:Pregnancy Trimester, Third; D011379:Prognosis; D055815:Young Adult
keywords: Cushing’s syndrome; Laparoscopic adrenalectomy; Pregnancy