title: Paediatric obesity: can medications help.
abstract: OBJECTIVE
  The purpose of this study is to review current and emergent antiobesity drugs in paediatrics.
  
  
  RESULTS
  Understanding of the pathophysiology of obesity is improving, but access to antiobesity drugs continues to be challenging, especially in paediatrics. Few antiobesity drug trials have been conducted in paediatrics and postmarketing findings remain a source of concern. New approaches by the European Medicines Agency and the US Food and Drug Administration have provided guidance for the development of antiobesity drugs. However, few are in the pipeline and high-quality trials in paediatrics are lacking.
  
  
  CONCLUSIONS
  We are providing a summary of available antiobesity drug therapies, barriers to treatment and emerging pharmacotherapies.
authors.affiliation: Nutrition and Fitness for Life program, Boston Medical Center, Boston, Massachusetts, USA.
authors.forename: Carine M
authors.initials: CM
authors.lastname: Lenders
mesh_terms: D019440:Anti-Obesity Agents / Q000627:therapeutic use*; D002648:Child; D002986:Clinical Trials as Topic; D017277:Drug Approval; D006801:Humans; D063766:Pediatric Obesity / Q000188:drug therapy*
chemical_list: D019440:Anti-Obesity Agents