title: One-pot synthesis of 1,3-enynes with a CF3 group on the terminal sp(2) carbon by an oxidative Sonogashira cross-coupling reaction.
abstract: Oxidative Sonogashira cross-coupling reactions of (E)-trimethyl(3,3,3-trifluoroprop-1-enyl)silane with arylacetylene were achieved using silver fluoride and a palladium catalyst, to afford high yields of various 1,3-enynes with a CF3 group on the terminal sp(2) carbon. Silver fluoride promoted C-Si bond dissociation and oxidation of palladium, enabling catalytic use of palladium.
authors.affiliation: Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan. aando@pharm.setsunan.ac.jp.
authors.forename: Akari
authors.initials: A
authors.lastname: Ikeda
authors.forename: Masaaki
authors.initials: M
authors.lastname: Omote
authors.forename: Kana
authors.initials: K
authors.lastname: Kusumoto
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tarui
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Sato
authors.forename: Akira
authors.initials: A
authors.lastname: Ando
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002625:Chemistry, Organic / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D058451:Oxidative Coupling
chemical_list: D000480:Alkynes; D002244:Carbon