title: Increasing the Diversity of Known Pictet-Spenglerases.
abstract: Pictet-Spenglerases catalyze key condensation/cyclization reactions between aromatic ethylamines and aldehydes in the biosynthesis of alkaloids. In this issue of Chemistry & Biology, Mori et al. (2015) report the structural elucidation of a novel type of Pictet-Spenglerase involved in the biosynthesis of the β-carboline alkaloids.
authors.affiliation: Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada. Electronic address: mtanner@chem.ubc.ca.
authors.forename: Martin E
authors.initials: ME
authors.lastname: Tanner
mesh_terms: D000470:Alkaloids / Q000096:biosynthesis* / Q000737:chemistry*; D002243:Carbolines / Q000737:chemistry* / Q000378:metabolism*; D019759:Carbon-Nitrogen Lyases / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D000470:Alkaloids; D002243:Carbolines; D019759:Carbon-Nitrogen Lyases