title: Development of Port-Site Metastases Following Thoracoscopic Resection of a Neuroblastoma.
abstract: We report a 26-month-old female who developed port-site metastases of a neuroblastoma following minimally invasive thoracoscopic interventions. After diagnosis of an intrathoracic low-risk neuroblastoma and 6 months of observation, she developed respiratory problems. She subsequently underwent total resection of a locally progressive tumor via thoracoscopy. Six months later, she developed local relapse and subcutaneous metastases within the thoracic wall. These port-site metastases were most likely iatrogenic. After excision of metastases, the residual tumor responded well to salvage chemotherapy. The patient has remained in remission for over 4 years.
authors.affiliation: Department of Pediatric Hematology and Oncology, Kinderklinik III, Universitätsklinikum-Essen and the University of Duisburg-Essen, Essen, Germany.
authors.forename: Falk
authors.initials: F
authors.lastname: Pentek
authors.affiliation: Department of Pediatric Hematology and Oncology, Kinderklinik III, Universitätsklinikum-Essen and the University of Duisburg-Essen, Essen, Germany.|Charité Universitätsmedizin, Department of Pediatrics, Division of Oncology and Hematology, Berlin, Germany.|German Consortium for Translational Cancer Research (DKTK), Heidelberg, Germany.|Translational Neuro-Oncology, West German Cancer Center (WTZ), University Hospital Essen, Essen, Germany.
authors.forename: Johannes H
authors.initials: JH
authors.lastname: Schulte
authors.affiliation: Institute of Diagnostic and Interventional Radiology and Neuroradiology, Universitätsklinikum-Essen and the University of Duisburg-Essen, Essen, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Schweiger
authors.affiliation: Division of Pediatric Surgery, Universitätsklinikum-Essen and the University of Duisburg-Essen, Essen, Germany.|Department of Pediatric Surgery, Medical University Vienna, Vienna, Austria.
authors.forename: Martin
authors.initials: M
authors.lastname: Metzelder
authors.affiliation: Department of Pediatric Hematology and Oncology, Kinderklinik III, Universitätsklinikum-Essen and the University of Duisburg-Essen, Essen, Germany.
authors.forename: Michael M
authors.initials: MM
authors.lastname: Schündeln
mesh_terms: D002675:Child, Preschool; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D009366:Neoplasm Seeding; D009447:Neuroblastoma / Q000473:pathology* / Q000601:surgery*; D013899:Thoracic Neoplasms / Q000473:pathology* / Q000601:surgery*; D013906:Thoracoscopy
keywords: minimally invasive surgery; neuroblastoma metastases; port-site metastases; thoracoscopy