title: Symbiotic maple saps minimize disruption of the mice intestinal microbiota after oral antibiotic administration.
abstract: This study was undertaken to evaluate the in vivo impact of new symbiotic products based on liquid maple sap or its concentrate. Sap and concentrate, with or without inulin (2%), were inoculated with Bifidobacterium lactis Bb12 and Lactobacillus rhamnosus GG valio at initial counts of 2-4 × 10(8) cfu mL(-1). The experiments started with intra-gastric administration of antibiotic (kanamycin 40 mg in 0.1 cc) (to induce microbiota disturbance and/or diarrhea) to 3-to-5-week-old C57BL/6 female mice followed by a combination of prebiotic and probiotics included in the maple sap or its concentrate for a week. The combination inulin and probiotics in maple sap and concentrate appeared to minimize the antibiotic-induced breakdown of mice microbiota with a marked effect on bifidobacterium and bacteroides levels, thus permitting a more rapid re-establishment of the baseline microbiota levels. Results suggest that maple sap and its concentrate represent good candidates for the production of non-dairy functional foods.
authors.affiliation: a STELA Dairy Research Centre, Institute of Nutrition and Functional Foods, Université Laval , Québec , Canada and.
authors.forename: Riadh
authors.initials: R
authors.lastname: Hammami
authors.affiliation: a STELA Dairy Research Centre, Institute of Nutrition and Functional Foods, Université Laval , Québec , Canada and.
authors.forename: Nour
authors.initials: N
authors.lastname: Ben Abdallah
authors.affiliation: b Fédération des Producteurs Acéricoles du Québec , Longueuil, Québec , Canada.
authors.forename: Julie
authors.initials: J
authors.lastname: Barbeau
authors.affiliation: a STELA Dairy Research Centre, Institute of Nutrition and Functional Foods, Université Laval , Québec , Canada and.
authors.forename: Ismail
authors.initials: I
authors.lastname: Fliss
mesh_terms: D031002:Acer / Q000737:chemistry*; D000284:Administration, Oral; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001439:Bacteroides / Q000187:drug effects / Q000254:growth & development; D001644:Bifidobacterium / Q000187:drug effects / Q000502:physiology; D003013:Clostridium / Q000187:drug effects / Q000254:growth & development; D005260:Female; D007422:Intestines / Q000382:microbiology*; D007444:Inulin / Q000378:metabolism; D007612:Kanamycin / Q000008:administration & dosage / Q000494:pharmacology*; D052201:Lacticaseibacillus rhamnosus / Q000502:physiology; D051379:Mice; D008810:Mice, Inbred C57BL; D064307:Microbiota / Q000187:drug effects*; D056692:Prebiotics; D019936:Probiotics; D011897:Random Allocation; D013047:Specific Pathogen-Free Organisms; D013559:Symbiosis
chemical_list: D000900:Anti-Bacterial Agents; D056692:Prebiotics; D007612:Kanamycin; D007444:Inulin
keywords: Diarrhea; maple saps; mice microbiota; prebiotic; probiotics; symbiotic drink