title: How Bioethics is Complementing Human Rights in Realizing Health Access for Clinical Trial Participants: The Case of Formative PrEP Access in South Africa.
abstract: Following the demise of apartheid, human rights in South Africa are now constitutionally enshrined.The right to health in South Africa's Constitution has been credited with transforming the lives of millions of people by triggering programmatic reforms in HIV treatment and the prevention of mother to child transmission (MTCT) of HIV.However, a constitutionally enshrined right to health offers no guarantee that clinical trial participants will enjoy post-trial access to beneficial interventions. Using access to HIV pre-exposure prophylaxis (PrEP) in South Africa as an example, this paper argues that adherence to bioethics norms could realize the right to health for trial participants following the end of a clinical trial.
authors.affiliation: Head of Ethics and Law, Center for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa, and Adjunct Professor at the Dalla Lana School of Public Health and Joint Centre for Bioethics, University of Toronto, Canada.
authors.forename: Jerome
authors.initials: J
authors.lastname: Singh
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use; D002986:Clinical Trials as Topic / Q000941:ethics*; D015658:HIV Infections / Q000517:prevention & control; D006291:Health Policy; D006297:Health Services Accessibility; D006806:Human Rights; D006801:Humans; D035842:Research Subjects; D013019:South Africa
chemical_list: D019380:Anti-HIV Agents