title: Targeted vaccination of teenagers following continued rapid endemic expansion of a single meningococcal group W clone (sequence type 11 clonal complex), United Kingdom 2015.
abstract: Since the epidemiological year 2009/10, the United Kingdom has experienced a year-on-year increase in meningococcal group W (MenW) disease due to rapid expansion of a single endemic hyper-virulent strain belonging to sequence type 11 clonal complex (cc). This strain was identified among cases diagnosed across all regions and was not linked to travel abroad. Consequently, an adolescent MenACWY conjugate vaccination programme for 13-18 year-olds will be introduced in August 2015, with priority given to 17-18 year-olds (school leavers).
authors.affiliation: Public Health England, Immunisation Department, London, United Kingdom.
authors.forename: H
authors.initials: H
authors.lastname: Campbell
authors.forename: V
authors.initials: V
authors.lastname: Saliba
authors.forename: R
authors.initials: R
authors.lastname: Borrow
authors.forename: M
authors.initials: M
authors.lastname: Ramsay
authors.forename: S N
authors.initials: SN
authors.lastname: Ladhani
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D000942:Antigens, Bacterial / Q000276:immunology; D004196:Disease Outbreaks; D019353:Endemic Diseases; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D017589:Immunization Programs; D008297:Male; D008585:Meningitis, Meningococcal / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D008589:Meningococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D022401:Meningococcal Vaccines / Q000008:administration & dosage*; D009345:Neisseria meningitidis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D010641:Phenotype; D016133:Polymerase Chain Reaction; D006113:United Kingdom / Q000453:epidemiology; D014611:Vaccination / Q000379:methods*; D018074:Vaccines, Conjugate / Q000008:administration & dosage
chemical_list: D000942:Antigens, Bacterial; C525703:MenACWY; D022401:Meningococcal Vaccines; D018074:Vaccines, Conjugate