title: Responsive hairpin DNA aptamer switch to program the strand displacement reaction for the enhanced electrochemical assay of ATP.
abstract: A responsive hairpin DNA aptamer switch was ingeniously designed for enzyme-free, sensitive and selective electrochemical detection of ATP. It takes full advantage of the target-triggered liberation effect of the toehold region and the concomitant proximity effect with the branch-migration region to execute the toehold-mediated strand displacement reaction on the electrode surface.
authors.affiliation: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, No. 53, Zhengzhou Rd., Qingdao, Shandong 266042, China. sliu@qust.edu.cn.
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Li
authors.initials: L
authors.lastname: Fang
authors.forename: Shufeng
authors.initials: S
authors.lastname: Liu
mesh_terms: D000255:Adenosine Triphosphate / Q000032:analysis*; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015342:DNA Probes / Q000737:chemistry; D055664:Electrochemical Techniques; D004566:Electrodes; D061925:Immobilized Nucleic Acids / Q000737:chemistry
chemical_list: D052157:Aptamers, Nucleotide; D015342:DNA Probes; D061925:Immobilized Nucleic Acids; D000255:Adenosine Triphosphate