title: Antioxidant and antiproliferative activities in different maturation stages of broccoli (Brassica oleracea Italica) biofortified with selenium.
abstract: In this work, three different broccoli maturity stages subjected to biofortification with selenium were evaluated for antioxidant and antiproliferative activities. Antioxidant trials have shown that the maturation stages biofortified with selenium had significantly higher amounts of phenolic compounds and antioxidant activity, especially seedlings. Although non-polar extracts of all samples show antiproliferative activity, the extract of broccoli seedlings biofortified with selenium stood out, presenting cytocidal activity for a glioma line (U251, GI50 28.5 mg L(-1)).
authors.affiliation: Departamento de Agroindústria, Alimentos e Nutrição, Laboratório de Bromatologia, Escola Superior de Agricultura "Luiz de Queiroz"/Universidade de São Paulo (Esalq/USP), Avenida Pádua Dias, 111, 13418-900 Piracicaba, SP, Brazil. Electronic address: patriciabachiega@hotmail.com.
authors.forename: Patricia
authors.initials: P
authors.lastname: Bachiega
authors.affiliation: Departamento de Agroindústria, Alimentos e Nutrição, Laboratório de Bromatologia, Escola Superior de Agricultura "Luiz de Queiroz"/Universidade de São Paulo (Esalq/USP), Avenida Pádua Dias, 111, 13418-900 Piracicaba, SP, Brazil.
authors.forename: Jocelem Mastrodi
authors.initials: JM
authors.lastname: Salgado
authors.affiliation: Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas, UNICAMP, CP 6171, 13083-970 Paulínia, SP, Brazil.
authors.forename: João Ernesto
authors.initials: JE
authors.lastname: de Carvalho
authors.affiliation: Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas, UNICAMP, CP 6171, 13083-970 Paulínia, SP, Brazil.
authors.forename: Ana Lúcia T G
authors.initials: ALTG
authors.lastname: Ruiz
authors.affiliation: Centro de Energia Nuclear na Agricultura (CENA)/Universidade de São Paulo (USP), Avenida Centenário, 303, 13418900 Piracicaba, SP, Brazil.
authors.forename: Kélin
authors.initials: K
authors.lastname: Schwarz
authors.affiliation: Departamento de Produção Vegetal, Laboratório Multiusuário em Produção Vegetal, Escola Superior de Agricultura "Luiz de Queiroz"/Universidade de São Paulo (Esalq/USP), Avenida Pádua Dias, 111, 13418-900 Piracicaba, SP, Brazil.
authors.forename: Tiago
authors.initials: T
authors.lastname: Tezotto
authors.affiliation: Departamento de Agroindústria, Alimentos e Nutrição, Laboratório de Bromatologia, Escola Superior de Agricultura "Luiz de Queiroz"/Universidade de São Paulo (Esalq/USP), Avenida Pádua Dias, 111, 13418-900 Piracicaba, SP, Brazil.
authors.forename: Maressa Caldeira
authors.initials: MC
authors.lastname: Morzelle
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D001937:Brassica / Q000737:chemistry*; D010636:Phenols; D012643:Selenium / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D010636:Phenols; D012643:Selenium
keywords: Antioxidant; Antiproliferative; Broccoli; Glucosinolates; Sodium selenate