title: Hyperpolarized NMR of plant and cancer cell extracts at natural abundance.
abstract: Natural abundance (13)C NMR spectra of biological extracts are recorded in a single scan provided that the samples are hyperpolarized by dissolution dynamic nuclear polarization combined with cross polarization. Heteronuclear 2D correlation spectra of hyperpolarized breast cancer cell extracts can also be obtained in a single scan. Hyperpolarized NMR of extracts opens many perspectives for metabolomics.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS UPR 2301, F-91190 Gif-sur-Yvette, France.
authors.forename: Jean-Nicolas
authors.initials: JN
authors.lastname: Dumez
authors.forename: Jonas
authors.initials: J
authors.lastname: Milani
authors.forename: Basile
authors.initials: B
authors.lastname: Vuichoud
authors.forename: Aurélien
authors.initials: A
authors.lastname: Bornet
authors.forename: Julie
authors.initials: J
authors.lastname: Lalande-Martin
authors.forename: Illa
authors.initials: I
authors.lastname: Tea
authors.forename: Maxime
authors.initials: M
authors.lastname: Yon
authors.forename: Mickaël
authors.initials: M
authors.lastname: Maucourt
authors.forename: Catherine
authors.initials: C
authors.lastname: Deborde
authors.forename: Annick
authors.initials: A
authors.lastname: Moing
authors.forename: Lucio
authors.initials: L
authors.lastname: Frydman
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Bodenhausen
authors.forename: Sami
authors.initials: S
authors.lastname: Jannin
authors.forename: Patrick
authors.initials: P
authors.lastname: Giraudeau
mesh_terms: D001688:Biological Products / Q000737:chemistry*; D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology; D002247:Carbon Isotopes / Q000737:chemistry; D045744:Cell Line, Tumor; D005260:Female; D006801:Humans; D018551:Solanum lycopersicum / Q000737:chemistry / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D019906:Nuclear Magnetic Resonance, Biomolecular; D010944:Plants / Q000737:chemistry* / Q000378:metabolism
chemical_list: D001688:Biological Products; D002247:Carbon Isotopes