title: Iridoids and phenylethanoid from Pedicularis kerneri Dalla Torre growing in Dolomites, Italy.
abstract: In this study, we report the first phytochemical analysis of polar fraction of Pedicularis kerneri Dalla Torre growing in Dolomites, Italy. Several iridoid glucosides were isolated, namely aucubin (1), monomelittoside (2), plantarenaloside (3), euphroside (4), mussaenosidic acid (5) and 8-epiloganic acid (6), showing a composition in accordance with previous study on this genus. The studied samples, collected from Dolomites, presented a chemotype already recognised in species from North America, characterised by euphroside (4) and aucubin (1) as main components, but the main character was the presence of monomelittoside (2) never reported in this genus. The identification of verbascoside (7), leucosceptoside A (9) and echinacoside (10) complete the systematic framing of this species since is ascertained the co-occurrence of phenylethanoid glycosides with iridoids in Lamiales species.
authors.affiliation: a Dipartimento di Chimica , Sapienza Università di Roma , P.le A. Moro 5, 00185 Roma , Italy.|b Dipartimento di Biologia Ambientale , Sapienza Università di Roma , P.le A. Moro 5, 00185 Roma , Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Venditti
authors.affiliation: b Dipartimento di Biologia Ambientale , Sapienza Università di Roma , P.le A. Moro 5, 00185 Roma , Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Frezza
authors.affiliation: b Dipartimento di Biologia Ambientale , Sapienza Università di Roma , P.le A. Moro 5, 00185 Roma , Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Serafini
authors.affiliation: a Dipartimento di Chimica , Sapienza Università di Roma , P.le A. Moro 5, 00185 Roma , Italy.
authors.forename: Armandodoriano
authors.initials: A
authors.lastname: Bianco
mesh_terms: D005960:Glucosides / Q000302:isolation & purification; D006027:Glycosides / Q000302:isolation & purification; D057888:Iridoid Glucosides / Q000737:chemistry* / Q000302:isolation & purification*; D039823:Iridoids / Q000302:isolation & purification; D007558:Italy; D015394:Molecular Structure; D032262:Pedicularis / Q000737:chemistry*; D010636:Phenols / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry; D059808:Polyphenols
chemical_list: D005960:Glucosides; D006027:Glycosides; D057888:Iridoid Glucosides; D039823:Iridoids; D010636:Phenols; D010936:Plant Extracts; C000609650:monomelittoside; C002947:loganic acid; C006650:aucubin; C058956:acteoside; D059808:Polyphenols; C060297:echinacoside
keywords: Orobanchaceae; Pedicularis kerneri Dalla Torre; hemiparasitic plant; iridoids; monomelittoside; phenylethanoid glycosides