title: Determination of 2,8-dichlorodibenzo-p-dioxin in toothpaste and mouthwash consumer products using GC-MS.
abstract: A gas chromatography-mass spectrometry (GC-MS) method was developed for the identification and quantification of 2,8-dichlorodibenzo-p-dioxin (2,8-DCDD) in toothpaste and mouthwash consumer products. Liquid-liquid extraction and solid-phase extraction were used in the sample preparation. The limit of detection was 0.96 ng/g in toothpaste and 0.83 ng/g in mouthwash. The accuracy represented by relative errors was less than 12.5%. The intra-day and inter-day precision, which are represented by the relative standard deviation values, were within 11.2 and 10.6%, respectively. The method was successfully applied to analyze 2,8-DCDD in toothpaste and mouthwash products, as well as that from the photo-degradation of triclosan spiked in both sample matrix.
authors.affiliation: State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong, SAR, China.
authors.forename: Jianlin
authors.initials: J
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong, SAR, China.|School of Food and Chemical Engineering, Beijing Technology and Business University, Beijing, China.
authors.forename: Chuanqin
authors.initials: C
authors.lastname: Hu
authors.affiliation: California Department of Public Health, Richmond, CA, 94564, USA.
authors.forename: Charlie
authors.initials: C
authors.lastname: Li
authors.affiliation: State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong, SAR, China. zwcai@hkbu.edu.hk.
authors.forename: Zongwei
authors.initials: Z
authors.lastname: Cai
authors.affiliation: State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong, SAR, China. dihu@hkbu.edu.hk.
authors.forename: Di
authors.initials: D
authors.lastname: Hu
mesh_terms: D004147:Dioxins / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D059625:Liquid-Liquid Extraction; D009067:Mouthwashes / Q000032:analysis*; D052616:Solid Phase Extraction; D014100:Toothpastes / Q000032:analysis*; D014260:Triclosan / Q000032:analysis / Q000737:chemistry
chemical_list: D004147:Dioxins; D009067:Mouthwashes; D014100:Toothpastes; D014260:Triclosan; C503656:dichlorodibenzo-p-dioxin; C068993:2,8-dichlorodibenzo-4-dioxin
keywords: 2,8-dichlorodibenzo-p-dioxin (2,8-DCDD); Gas chromatography–mass spectrometry; Mouthwash; Toothpaste