title: PYODERMA GANGRENOSUM IN BURNED PATIENT - CASE REPORT.
abstract: BACKGROUND
  Pyoderma gangrenosum is a rare, chronic, destructive, ulcerating skin disease of uncertain etiology. It develops most frequently in patients between 25-45 years of age and affects both sexes equally.
  
  
  METHODS
  We present a case of pyoderma gangrenosum in a young female patient who sustained a burn injury of 40% total body surface area. She underwent four operations. She developed a wound infection and urinary infection during her hospital stay. By the end of hospitalization, the papules followed with coalesce of ulcerations formed on the previously epithelized areas of her legs. The patient complained of the intensive pain localized on these surfaces. Since pyoderma gangrenosum was suspected, a dermatologist was included in treatment. Therapy was initiated (methylprednisolone 60 mg per day intravenously) with gradual reduction of the dosage. The patient was discharged from hospital two weeks later with almost fully complete cicatrization and epithelization.
  
  
  CONCLUSIONS
  Pyoderma gangrenosum is still difficult to be diagnosed in the absence of specific and sensitive diagnostic methods; however, it is crucial to be suspected as early as possible and to start treatment immediately. Multidisciplinary approach is essential for ontimal results.
authors.forename: Milana
authors.initials: M
authors.lastname: Obradović Tomašev
authors.forename: Mladen
authors.initials: M
authors.lastname: Jovanović
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Popović
mesh_terms: D002056:Burns / Q000150:complications* / Q000628:therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D016038:Skin Transplantation / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone