title: Ultrasonographic Features of the Major Salivary Glands after Radioactive Iodine Ablation in Patients with Papillary Thyroid Carcinoma.
abstract: The aim of this study was to evaluate the ultrasonographic features of the major salivary glands (MSGs) after post-operative radioactive iodine ablation (RIA) in patients with papillary thyroid carcinoma (PTC). The study population comprised 202 consecutively registered PTC patients who had undergone total thyroidectomy, RIA and follow-up neck ultrasonography. The ultrasonographic features of the MSGs in each patient were retrospectively evaluated by a single radiologist, and the presence of post-RIA changes was determined by direct comparisons of pre- and post-RIA follow-up ultrasonographic scans. Of the 202 patients, 94 (46.5%) had post-RIA changes in the MSGs on follow-up ultrasonography. RIA dose was closely associated with the prevalence of post-RIA changes. Post-RIA changes were more common in the parotid glands (n = 93, 46.0%) than in the submandibular glands (n = 7, 3.5%). Common ultrasonographic findings representing post-RIA changes in MSGs included coarse echotexture, decreased echogenicity, lobulated margin and decreased gland size.
authors.affiliation: Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea. Electronic address: dwultra@lycos.co.kr.
authors.forename: Dong Wook
authors.initials: DW
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D002291:Carcinoma, Papillary; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000000981:diagnostic imaging* / Q000209:etiology*; D019275:Radiopharmaceuticals / Q000009:adverse effects / Q000627:therapeutic use; D015203:Reproducibility of Results; D012466:Salivary Gland Diseases / Q000000981:diagnostic imaging* / Q000209:etiology*; D012680:Sensitivity and Specificity; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals
keywords: Computed tomography; Major salivary glands; Papillary thyroid carcinoma; Radioactive iodine ablation; Ultrasonography