title: The functional exercise capacity in patients with bipolar disorder versus healthy controls: A pilot study.
abstract: The aim of the current study was to compare the functional exercise capacity of patients with bipolar disorder with age-, gender- and body mass index (BMI)-matched healthy controls. Thirty patients (16 ♂, 40.8±11.6 years) and healthy controls (16 ♂, 40.5±10.8 years) were included. All participants performed a 6-min walk test to assess the functional exercise capacity and completed the International Physical Activity Questionnaire. Patients were screened for psychiatric symptoms using the Quick Inventory of Depressive Symptomatology and Hypomania Checklist-32. Results demonstrated that patients with bipolar disorder demonstrated a significantly poorer functional exercise capacity (590.8±112.6 versus 704.2±94.3m). A backward stepwise regression analyses showed that the level of depression and existing foot or ankle static problems and back pain before the test explained 70.9% of the variance in the distance achieved on the 6-min walk test (functional exercise capacity). The current study demonstrates that foot and back pain appear to be important negative predictors of functional exercise capacity in patients with bipolar disorder. Physical activity interventions delivered by physical therapists may help ameliorate pain symptoms and improve functional exercise capacity.
authors.affiliation: KU Leuven - University of Leuven Department of Rehabilitation Sciences, Tervuursevest 101, 3001 Leuven, Belgium; UPC KU Leuven, Campus Kortenberg, KU Leuven - University of Leuven Department of Neurosciences, Leuvensesteenweg 517, 3070 Kortenberg, Belgium. Electronic address: Davy.Vancampfort@uc-kortenberg.be.
authors.forename: Davy
authors.initials: D
authors.lastname: Vancampfort
authors.affiliation: UPC KU Leuven, Campus Kortenberg, KU Leuven - University of Leuven Department of Neurosciences, Leuvensesteenweg 517, 3070 Kortenberg, Belgium.
authors.forename: Sabine
authors.initials: S
authors.lastname: Wyckaert
authors.affiliation: UPC KU Leuven, Campus Kortenberg, KU Leuven - University of Leuven Department of Neurosciences, Leuvensesteenweg 517, 3070 Kortenberg, Belgium.
authors.forename: Pascal
authors.initials: P
authors.lastname: Sienaert
authors.affiliation: KU Leuven - University of Leuven Department of Rehabilitation Sciences, Tervuursevest 101, 3001 Leuven, Belgium; UPC KU Leuven, Campus Kortenberg, KU Leuven - University of Leuven Department of Neurosciences, Leuvensesteenweg 517, 3070 Kortenberg, Belgium.
authors.forename: Marc
authors.initials: M
authors.lastname: De Hert
authors.affiliation: School of Health and Social Care, University of Greenwich, Southwood Site Avery Hill Road, Eltham, London SE9 2UG, UK.
authors.forename: Brendon
authors.initials: B
authors.lastname: Stubbs
authors.affiliation: KU Leuven - University of Leuven Department of Rehabilitation Sciences, Tervuursevest 101, 3001 Leuven, Belgium.
authors.forename: Roselien
authors.initials: R
authors.lastname: Buys
authors.affiliation: UPC KU Leuven, Campus Kortenberg, KU Leuven - University of Leuven Department of Neurosciences, Leuvensesteenweg 517, 3070 Kortenberg, Belgium.
authors.forename: Ans
authors.initials: A
authors.lastname: Schueremans
authors.affiliation: KU Leuven - University of Leuven Department of Rehabilitation Sciences, Tervuursevest 101, 3001 Leuven, Belgium; UPC KU Leuven, Campus Kortenberg, KU Leuven - University of Leuven Department of Neurosciences, Leuvensesteenweg 517, 3070 Kortenberg, Belgium.
authors.forename: Michel
authors.initials: M
authors.lastname: Probst
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis / Q000523:psychology*; D015992:Body Mass Index; D015444:Exercise / Q000502:physiology / Q000523:psychology*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D010809:Physical Fitness / Q000502:physiology / Q000523:psychology*; D010865:Pilot Projects; D011795:Surveys and Questionnaires; D016138:Walking / Q000502:physiology / Q000523:psychology*
keywords: Bipolar Disorder; Exercise; Physical Fitness; Physical activity