title: New cyclic tetrapeptide from the coral-derived endophytic bacteria Brevibacterium sp. L-4 collected from the South China Sea.
abstract: One new cyclic tetrapeptide cyclic-(Tyr-Ala-Leu-Ser) (1) along with four natural compounds firstly obtained 3H-imidazole-4-carboxylic acid (2), 2-methyl-3H-imidazole-4-carboxylic acid (3), 3-ethylidene-6-isopropyl-piperazine-2,5-dione (4), and 3-isobutylidene-6-methyl piperazine-2,5-dione (5) have been isolated from the coral derived endophytic bacteria Brevibacterium sp. L-4 collected from the South China Sea. Their structures were elucidated through spectroscopic techniques including NMR (1D and 2D), MS, and EA, and their relative configurations were also assigned by NMR analysis.
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Bing-Xin
authors.initials: BX
authors.lastname: Liu
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Guo
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Guang-Tian
authors.initials: GT
authors.lastname: Peng
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Xi-Xin
authors.initials: XX
authors.lastname: He
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Xiao-Jie
authors.initials: XJ
authors.lastname: Chen
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Ling-Fang
authors.initials: LF
authors.lastname: Lei
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Deng
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Xian
authors.initials: X
authors.lastname: Jun Su
authors.affiliation: a School of Chinese Materia Medica, Guangzhou University of Chinese Medicine , Guangzhou 510006 , P.R. China.
authors.forename: Cui-Xian
authors.initials: CX
authors.lastname: Zhang
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000382:microbiology*; D001951:Brevibacterium / Q000737:chemistry*; D060026:Endophytes / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009792:Oceans and Seas; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000302:isolation & purification; D010879:Piperazines / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D007093:Imidazoles; D010456:Peptides, Cyclic; D010879:Piperazines
keywords: 3-ylidene-2,5-piperazinediones; Brevibacterium sp. L-4; coral derived endophytic bacteria; tetrapeptide