title: [Analysis of Musculoskeletal Systems and Their Diseases. The research for musculoskeletal disease using genome editing technology].
abstract: Genome editing is a genetic technology by which any DNA sequence is inserted, replaced or deleted. Genome editing has been making rapid progress recently, with the development of new techniques such as ZFN, TALEN and CRISPR/Cas9. Genome editing can be applied to various fields ranging from the production of knock out animals to gene therapy. This section summarizes these new genome editing technologies and its applications.
authors.affiliation: Department of Systems BioMedicine, Tokyo Medical and Dental University, Japan.
authors.forename: Hidetsugu
authors.initials: H
authors.lastname: Suzuki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Asahara
mesh_terms: D000818:Animals; D064130:CRISPR-Associated Proteins / Q000235:genetics / Q000378:metabolism*; D064112:Clustered Regularly Interspaced Short Palindromic Repeats; D015316:Genetic Therapy; D016678:Genome; D006801:Humans; D009140:Musculoskeletal Diseases / Q000235:genetics / Q000628:therapy*
chemical_list: D064130:CRISPR-Associated Proteins