title: Transcriptional and epigenetic insights from stem cells and developing tissues.
abstract: In March 2015, over 200 scientists gathered in Steamboat Springs, Colorado, USA, for the Keystone Symposium 'Transcriptional and Epigenetic Influences on Stem Cell States' to discuss the molecular mechanisms of pluripotency, cell differentiation, cell reprogramming and transdifferentiation, among other topics. In this meeting, translational research on stem cells for disease modeling and therapy was also presented. This Meeting Review describes key themes and selected findings, providing a timely update on this fast-moving area of research.
authors.affiliation: Department of Neurological Surgery, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco Veterans Affairs Medical Center, University of California, San Francisco, San Francisco, CA 94143, USA limd@neurosurg.ucsf.edu.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Lim
mesh_terms: D019070:Cell Lineage / Q000502:physiology*; D002843:Chromatin / Q000502:physiology*; D044127:Epigenesis, Genetic / Q000502:physiology*; D006801:Humans; D013234:Stem Cells / Q000502:physiology*; D014158:Transcription, Genetic / Q000502:physiology*; D057170:Translational Research, Biomedical / Q000639:trends*
chemical_list: D002843:Chromatin
keywords: Developing tissues; Epigenetic regulation; Single cells; Stem cells; Transcriptional regulation; Transdifferentiation