title: Cu-Catalyzed direct cyanation of terminal alkynes with AMBN or AIBN as the cyanation reagent.
abstract: A Cu-catalyzed direct cyanation of terminal alkynes was reported with broad substrate generality in moderate to high yield, and AMBN (azobisisoamylonitrile)/AIBN (azobisisobutyronitrile) were used as less toxic and effective cyanating sources in open air. Interestingly, addition products were selectively achieved as the major product under the same conditions in argon.
authors.affiliation: Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China. xinfangxu@suda.edu.cn.
authors.forename: Guangwei
authors.initials: G
authors.lastname: Rong
authors.forename: Jincheng
authors.initials: J
authors.lastname: Mao
authors.forename: Yang
authors.initials: Y
authors.lastname: Zheng
authors.forename: Ruwei
authors.initials: R
authors.lastname: Yao
authors.forename: Xinfang
authors.initials: X
authors.lastname: Xu
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis*; D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry*; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D001391:Azo Compounds; D007202:Indicators and Reagents; D009570:Nitriles; C000607978:azobisisoamylonitrile; D003300:Copper; C004526:azobis(isobutyronitrile)