title: Lack of Measles Transmission to Susceptible Contacts from a Health Care Worker with Probable Secondary Vaccine Failure - Maricopa County, Arizona, 2015.
abstract: On January 23, 2015, the Maricopa County Department of Public Health (MCDPH) was notified of a suspected measles case in a nurse, a woman aged 48 years. On January 11, the nurse had contact with a patient with laboratory-confirmed measles associated with the Disneyland theme park-related outbreak in California. On January 21, she developed a fever (103°F [39.4°C]), on January 23 she experienced cough and coryza, and on January 24, she developed a rash. The patient was instructed to isolate herself at home. On January 26, serum, a nasopharyngeal swab, and a urine specimen were collected. The following day, measles infection was diagnosed by real time reverse transcription polymerase chain reaction testing of the nasopharyngeal swab and urine specimen and by detection of measles-specific immunoglobulin (Ig)M and IgG in serum by enzyme-linked immunosorbent assay. Because of her symptoms and laboratory results, the patient was considered to be infectious.
authors.forename: Jefferson
authors.initials: J
authors.lastname: Jones
authors.forename: Ron
authors.initials: R
authors.lastname: Klein
authors.forename: Saskia
authors.initials: S
authors.lastname: Popescu
authors.forename: Karen
authors.initials: K
authors.lastname: Rose
authors.forename: Melissa
authors.initials: M
authors.lastname: Kretschmer
authors.forename: Alice
authors.initials: A
authors.lastname: Carrigan
authors.forename: Felicia
authors.initials: F
authors.lastname: Trembath
authors.forename: Lia
authors.initials: L
authors.lastname: Koski
authors.forename: Karen
authors.initials: K
authors.lastname: Zabel
authors.forename: Scott
authors.initials: S
authors.lastname: Ostdiek
authors.forename: Paula
authors.initials: P
authors.lastname: Rowell-Kinnard
authors.forename: Esther
authors.initials: E
authors.lastname: Munoz
authors.forename: Rebecca
authors.initials: R
authors.lastname: Sunenshine
authors.forename: Tammy
authors.initials: T
authors.lastname: Sylvester
mesh_terms: D000293:Adolescent; D001130:Arizona; D002648:Child; D002675:Child, Preschool; D016358:Contact Tracing; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D007231:Infant, Newborn; D017757:Infectious Disease Transmission, Professional-to-Patient; D008457:Measles / Q000175:diagnosis / Q000517:prevention & control / Q000635:transmission*; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage* / Q000276:immunology*; D008875:Middle Aged; D009726:Nurses; D017211:Treatment Failure
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M; D022542:Measles-Mumps-Rubella Vaccine