title: Sodium salts of anionic chiral cobalt(III) complexes as catalysts of the enantioselective Povarov reaction.
abstract: The sodium salts of anionic chiral cobalt(III) complexes (CCC(-) Na(+) ) have been found to be efficient catalysts of the asymmetric Povarov reaction of easily accessible dienophiles, such as 2,3-dihydrofuran, ethyl vinyl ether, and an N-protected 2,3-dihydropyrrole, with 2-azadienes. Ring-fused tetrahydroquinolines with up to three contiguous stereogenic centers were thus obtained in high yields, excellent diastereoselectivities (endo/exo up to >20:1), and high enantioselectivities (up to 95:5 e.r.).
authors.affiliation: Department of Applied Chemistry, Anhui Agricultural University (China).
authors.forename: Jie
authors.initials: J
authors.lastname: Yu
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China (China).
authors.forename: Hua-Jie
authors.initials: HJ
authors.lastname: Jiang
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China (China).
authors.forename: Ya
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China (China).
authors.forename: Shi-Wei
authors.initials: SW
authors.lastname: Luo
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China (China). gonglz@ustc.edu.cn.|Collaborative Innovation Centre of Chemical Science and Engineering, Tianjin (China). gonglz@ustc.edu.cn.
authors.forename: Liu-Zhu
authors.initials: LZ
authors.lastname: Gong
keywords: 2-azadienes; Povarov reaction; asymmetric catalysis; cobalt complexes; tetrahydroquinolines