title: Vabrasio is a reliable test to rule out endometrial cancer.
abstract: BACKGROUND
  Endometrial cancer is the most common gynaecological cancer in Denmark, and its incidence peaks in the postmenopausal years. The aim of the present study was to evaluate the effectiveness of vacuum aspirator (vabrasio) for the detection of endometrial cancer in terms of sensitivity, specificity and predictive value.
  
  
  METHODS
  A cohort counting 503 women who had vabrasio was evaluated retrospectively. The women included were consecutive patients who had received vabrasio at the Department of Gynaecology and Obstetrics at Herning Hospital, Denmark, during a two-year period. They were identified by searching the hospital database for the International Classification of Diseases, tenth version (ICD-10) code for vabrasio.
  
  
  RESULTS
  The indications for vabrasio were postmenopausal bleeding (45%), meno/metrorrhagia (43%) and thickened endometrium/polyp (6%). The first evaluation by vabrasio was normal in 381 women (76%), insufficient in 83 women (17%), 22 (4%) had endometrial cancer and 17 (3%) had another non-malignant diagnosis. The first evaluation for cancer with vabrasio had a sensitivity of 81%, a specificity of 100% and predictive values of 100% (positive) and 99% (negative).
  
  
  CONCLUSIONS
  Vabrasio has a good diagnostic reliability with respect to endometrial cancer, but has some shortcomings due to insufficient sampling for diagnosis.
  
  
  BACKGROUND
  none.
  
  
  BACKGROUND
  not relevant. Danish Data Protection Agency: case no.: 1-16-02-601-14.
authors.affiliation: Hospitalsenheden Vest, Gynækologisk-obstetrisk Afdeling, Regionshospitalet Herning, Gl. Landevej 61, 7400 Herning, Denmark. finlau@rm.dk.
authors.forename: Anita
authors.initials: A
authors.lastname: Andersen
authors.forename: Finn Friis
authors.initials: FF
authors.lastname: Lauszus
mesh_terms: D000328:Adult; D000368:Aged; D003718:Denmark; D055088:Early Detection of Cancer / Q000379:methods*; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000209:etiology; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D011127:Polyps / Q000150:complications; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014592:Uterine Hemorrhage / Q000150:complications; D014619:Vacuum Curettage / Q000379:methods / Q000706:statistics & numerical data*