title: Two-year clinical trial of a universal adhesive in total-etch and self-etch mode in non-carious cervical lesions.
abstract: OBJECTIVE
  To compare the clinical performance of Scotchbond™ Universal Adhesive used in self- and total-etch modes and two-bottle Scotchbond™ Multi-purpose Adhesive in total-etch mode for Class 5 non-carious cervical lesions (NCCLs).
  
  
  METHODS
  37 adults were recruited with 3 or 6 NCCLs (>1.5mm deep). Teeth were isolated, and a short cervical bevel was prepared. Teeth were restored randomly with Scotchbond Universal total-etch, Scotchbond Universal self-etch or Scotchbond Multi-purpose followed with a composite resin. Restorations were evaluated at baseline, 6, 12 and 24 months for marginal adaptation, marginal discoloration, secondary caries, and sensitivity to cold using modified USPHS Criteria. Patients and evaluators were blinded. Logistic and linear regression models using a generalized estimating equation were applied to evaluate the effects of time and adhesive material on clinical assessment outcomes over the 24 month follow-up period. Kaplan-Meier method was used to compare the retention between adhesive materials.
  
  
  RESULTS
  Clinical performance of all adhesive materials deteriorated over time for marginal adaptation, and discoloration (p<0.0001). Both Scotchbond Universal self-etch and Scotchbond Multi-purpose materials were more than three times as likely to contribute to less satisfying performance in marginal discoloration over time than Scotchbond Universal total-etch. The retention rates up to 24 months were 87.6%, 94.9% and 100% for Scotchbond Multi-purpose and Scotchbond Universal self-etch and total-etch, respectively.
  
  
  CONCLUSIONS
  Scotchbond Universal in self- and total- etch modes performed similar to or better than Scotchbond Multipurpose, respectively.
  
  
  CONCLUSIONS
  24 month evaluation of a universal adhesive indicates acceptable clinical performance, particularly in a total-etch mode.
authors.affiliation: University of Alabama at Birmingham School of Dentistry, Clinical and Community Sciences, Division of Biomaterials, 1919 7th Avenue South, Birmingham, AL 35205, USA. Electronic address: nlawson@uab.edu.
authors.forename: Nathaniel C
authors.initials: NC
authors.lastname: Lawson
authors.affiliation: University of Alabama at Birmingham School of Dentistry, Restorative Sciences, Division of General Dentistry, 1919 7th Avenue South, Birmingham, AL 35205, USA.
authors.forename: Augusto
authors.initials: A
authors.lastname: Robles
authors.affiliation: University of Alabama at Birmingham School of Dentistry, Restorative Sciences, Division of Prosthodontics, 1919 7th Avenue South, Birmingham, AL 35205, USA.
authors.forename: Chin-Chuan
authors.initials: CC
authors.lastname: Fu
authors.affiliation: UAB Center for Clinical and Translational Science, 401P Medical towers, 1717 11th Ave S, Birmingham, AL 35294, USA.
authors.forename: Chee Paul
authors.initials: CP
authors.lastname: Lin
authors.affiliation: University of Alabama at Birmingham School of Dentistry, Clinical and Community Sciences, Division of Biomaterials, 1919 7th Avenue South, Birmingham, AL 35205, USA.
authors.forename: Kanchan
authors.initials: K
authors.lastname: Sawlani
authors.affiliation: University of Alabama at Birmingham School of Dentistry, Clinical and Community Sciences, Division of Biomaterials, 1919 7th Avenue South, Birmingham, AL 35205, USA.
authors.forename: John O
authors.initials: JO
authors.lastname: Burgess
mesh_terms: D000134:Acid Etching, Dental / Q000379:methods*; D000269:Adhesives / Q000494:pharmacology; D003188:Composite Resins / Q000737:chemistry; D045662:Dental Etching / Q000379:methods; D018772:Dental Marginal Adaptation; D019232:Dental Restoration Failure; D003793:Dental Restoration, Permanent / Q000379:methods*; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019279:Resin Cements; D019237:Tooth Cervix / Q000473:pathology*
chemical_list: D000269:Adhesives; D003188:Composite Resins; D017220:Dentin-Bonding Agents; D019279:Resin Cements; C084018:Scotchbond Multi-Purpose
keywords: Non-carious cervical lesion; Self-etch; Total-etch; Universal adhesive