title: Atypical cytomegalovirus retinitis in non-Hodgkin's lymphoma.
abstract: A 54-year-old woman, a known case of non-Hodgkin's lymphoma (NHL) in complete remission, presented with floaters and diminution of vision in her left eye. The eye had vitritis with non-haemorrhagic retinitis mimicking intraocular lymphoma and acute retinal necrosis. A vitreous sample was positive for cytomegalovirus (CMV) and herpes simplex virus 1 (HSV-1) DNA by PCR. The possibility of intraocular lymphoma was not confirmed by the immunohistochemistry of the vitreous sample. The patient had a relapse of NHL along with rapid deterioration of vision in her left eye to no perception of light, due to optic nerve involvement. The right eye developed a new patch of focal haemorrhagic retinitis threatening the fovea. Based on the laboratory results and the clinical findings, she was successfully managed as a case of bilateral CMV retinitis and the vision in her right eye was salvaged.
authors.affiliation: Department of Retina, LV Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Mudit
authors.initials: M
authors.lastname: Tyagi
authors.affiliation: Department of Retina, LV Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Vikas
authors.initials: V
authors.lastname: Ambiya
authors.affiliation: Department of Retina, LV Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Annie
authors.initials: A
authors.lastname: Mathai
authors.affiliation: Department of Retina, LV Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Raja
authors.initials: R
authors.lastname: Narayanan
mesh_terms: D003587:Cytomegalovirus; D017726:Cytomegalovirus Retinitis / Q000150:complications / Q000175:diagnosis* / Q000821:virology; D004279:DNA, Viral; D005260:Female; D018259:Herpesvirus 1, Human; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D008875:Middle Aged; D009894:Opportunistic Infections / Q000821:virology; D009900:Optic Nerve; D016133:Polymerase Chain Reaction; D012008:Recurrence; D012160:Retina / Q000473:pathology / Q000821:virology*; D014786:Vision Disorders / Q000175:diagnosis* / Q000209:etiology; D014822:Vitreous Body / Q000473:pathology / Q000821:virology
chemical_list: D004279:DNA, Viral