title: Adherence to guidelines for surgical antibiotic prophylaxis: a review.
abstract: OBJECTIVE
  The appropriate use of antibiotic prophylaxis in the perioperative period may reduce the rate of infection in the surgical site. The purpose of this review was to evaluate adherence to guidelines for surgical antibiotic prophylaxis.
  
  
  METHODS
  The present systematic review was performed according to the Cochrane Collaboration methodology. The databases selected for this review were: Medline (via PubMed), Scopus and Portal (BVS) with selection of articles published in the 2004-2014 period from the Lilacs and Cochrane databases.
  
  
  RESULTS
  The search recovered 859 articles at the databases, with a total of 18 studies selected for synthesis. The outcomes of interest analyzed in the articles were as follows: appropriate indication of antibiotic prophylaxis (ranging from 70.3% to 95%), inappropriate indication (ranging from 2.3% to 100%), administration of antibiotic at the correct time (ranging from 12.73% to 100%), correct antibiotic choice (ranging from 22% to 95%), adequate discontinuation of antibiotic (ranging from 5.8% to 91.4%), and adequate antibiotic prophylaxis (ranging from 0.3% to 84.5%).
  
  
  CONCLUSIONS
  Significant variations were observed in all the outcomes assessed, and all the studies indicated a need for greater adherence to guidelines for surgical antibiotic prophylaxis.
authors.affiliation: Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio de Janeiro, RJ, Brazil; Master in Health and Technology of the Hospital Environment, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio de Janeiro, RJ, Brazil. Electronic address: marisegouvea@oi.com.br.
authors.forename: Marise
authors.initials: M
authors.lastname: Gouvêa
authors.affiliation: Postgraduate Program Professional Master in Health and Technology of the Hospital Environment, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio de Janeiro, RJ, Brazil.
authors.forename: Cristiane de Oliveira
authors.initials: Cde O
authors.lastname: Novaes
authors.affiliation: Librarian in Charge of the Reference Section of the Central Library of Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
authors.forename: Daniele Masterson Tavares
authors.initials: DM
authors.lastname: Pereira
authors.affiliation: Department of General and Specialized Surgery at Escola de Medicina e Cirurgia, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio de Janeiro, RJ, Brazil.
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: Iglesias
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D019072:Antibiotic Prophylaxis / Q000592:standards / Q000706:statistics & numerical data*; D019983:Guideline Adherence / Q000592:standards / Q000706:statistics & numerical data*; D006801:Humans; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotic prophylaxis; Antimicrobial prophylaxis; Guideline adherence; Surgical patient