title: Electrospinning of PEGylated polyamidoamine dendrimer fibers.
abstract: Polyamidoamine (PAMAM) dendrimers have emerged as an important class of nanostructured materials and have found a broad range of applications. There is also an ongoing effort to synthesize higher-complexity structures using PAMAM dendrimers as enabling building blocks. Herein, we report for the first time the fabrication of electrospun nanocomposite fibers composed of dendrimer derivatives, namely PEGylated PAMAM dendrimers, blended with a small amount of high-molecular-weight polyethylene oxide (PEO). Morphological features and mechanical properties of the resulting dendrimer fiber mats were assessed.
authors.affiliation: Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA.
authors.forename: Donald C
authors.initials: DC
authors.lastname: Aduba
authors.affiliation: Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA.
authors.forename: Jefferson W
authors.initials: JW
authors.lastname: Overlin
authors.affiliation: Department of Chemistry, Virginia Commonwealth University, Richmond, VA 23284, USA.
authors.forename: Chad D
authors.initials: CD
authors.lastname: Frierson
authors.affiliation: Department of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, USA.
authors.forename: Gary L
authors.initials: GL
authors.lastname: Bowlin
authors.affiliation: Department of Biomedical Engineering, Virginia Commonwealth University, Richmond, VA 23284, USA; Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298, USA. Electronic address: hyang2@vcu.edu.
authors.forename: Hu
authors.initials: H
authors.lastname: Yang
mesh_terms: D050091:Dendrimers / Q000737:chemistry*; D053761:Nanocomposites / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*
chemical_list: D050091:Dendrimers; C104700:PAMAM Starburst; D011092:Polyethylene Glycols; C000595209:polyethylene glycol 1000
keywords: Dendrimer; Electrospinning; Fast Fourier transform; Nanofiber; PEGylation