title: [Cutaneous lupus erythematosus].
abstract: Cutaneous lupus erythematosus (LE) is an autoimmune disease. The most common clinical forms are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE) and discoid LE (DLE). Cutaneous LE, mainly ACLE, can be the first sign of systemic LE (SLE). DLE and SCLE are less associated with development of SLE, however, up to 85% of patients with SLE have cutaneous manifestations. The aetiology is multifactorial. Drugs such as proton pump inhibitors can induce SCLE, while UV-light and smoking can worsen the lesions. Treatment includes preventive strategies in addition to topical steroids and systemic hydroxychloroquine.
authors.affiliation: Sdr. Boulevard 59, 2. th., 5000 Odense C. tatjana_sandreva@hotmail.com.
authors.forename: Tatjana
authors.initials: T
authors.lastname: Sandreva
authors.forename: Anne
authors.initials: A
authors.lastname: Voss
authors.forename: Anette
authors.initials: A
authors.lastname: Bygum
mesh_terms: D019091:Critical Pathways; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy