title: Acceptance rate of long-acting injection after short information: a survey in patients with first- and multiple-episode psychoses and their caregivers.
abstract: The aim of this study was to investigate the acceptance rates of long-acting injection (LAI) in patients with first- and multiple-episode psychoses before and after providing concise information about LAI to the patients and their caregivers. Additionally, predictors of choosing LAI and the reasons for reluctance to accept LAI were also evaluated.
  
  
  
  The survey included the questionnaire about participants' demographic characteristics, prior knowledge about LAI, attitude towards the importance of medication or psychotherapy and acceptance for LAI - treatment. The acceptance rate for LAI was re-evaluated after providing short information about current LAI or to the hypothetical questions like if there are a 3-ms lasting injection or the cost of injection is cheap.
  
  
  
  This study included 161 patients and 113 caregivers who completed a cross-sectional survey. Following exposure to LAI information, acceptance rates for this method of treatment did not change in all groups. However, acceptance rates increased significantly when asked if the cost of LAI was cheaper than the current oral medication and the effect of LAI lasted for 3 months. Significant predictors of acceptance of LAI in patients with first-episode psychosis were prior knowledge about LAI, attitudes towards the importance of medication and discomfort due to medication side-effects.
  
  
  
  The present study demonstrated that a substantial portion of patients with first- and multiple-episode psychoses and their caregivers prefer LAI over their current oral medication. The acceptance of LAI was not increased by providing succinct information concerning this method of treatment.
authors.affiliation: Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Seong-Uk
authors.initials: SU
authors.lastname: Yeo
authors.affiliation: Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Jong-Il
authors.initials: JI
authors.lastname: Park
authors.affiliation: Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Jin-Mahn
authors.initials: JM
authors.lastname: Jang
authors.affiliation: Maeumsarang Hospital, In-san Medical Foundation, Wanju, Korea.
authors.forename: Nam-In
authors.initials: NI
authors.lastname: Kang
authors.affiliation: Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea.|Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
authors.forename: Yin
authors.initials: Y
authors.lastname: Cui
authors.affiliation: Clinical Pharmacology Unit, Chonbuk National University Hospital and Research Institute of Clinical Medicine, Jeonju, Korea.
authors.forename: Min-Gul
authors.initials: MG
authors.lastname: Kim
authors.affiliation: Maeumsarang Hospital, In-san Medical Foundation, Wanju, Korea.
authors.forename: Hyun-Min
authors.initials: HM
authors.lastname: Kim
authors.affiliation: Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Ae-Ja
authors.initials: AJ
authors.lastname: Jung
authors.affiliation: Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Korea.|Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
authors.forename: Young-Chul
authors.initials: YC
authors.lastname: Chung
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D017028:Caregivers / Q000523:psychology*; D003692:Delayed-Action Preparations / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007267:Injections / Q000523:psychology; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000523:psychology*; D010353:Patient Education as Topic; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology*; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents; D003692:Delayed-Action Preparations
keywords: caregiver; first-episode psychosis; long-acting injection