title: Intraosseous verrucous carcinoma arising from an infected dentigerous cyst-A case report.
abstract: Intraosseous verrucous carcinoma (IOVC) arising from an odontogenic cyst is extremely rare. We report a case of intraosseous verrucous carcinoma in a 74-year-old male who presented with a left mandibular swelling with recurrent pus discharge from gingiva of tooth #35. Panoramic radiography revealed an impacted tooth #34 and a large well-defined, radiolucent lesion surrounding the crown of tooth #34. The clinical diagnosis was an infected dentigerous cyst. Surgical excision of the cyst together with extraction of tooth #34 was performed. Histopathological examination showed proliferation of hyperparakeratotic stratified squamous cyst lining epithelium and down-growth of broad and bulbous epithelial ridges with pushing border invasion into the fibrous cystic wall. A verrucous carcinoma arising from an infected dentigerous cyst was diagnosed. There was no recurrence of the tumor 5 months after surgery.
authors.affiliation: School of Dentistry, College of Oral Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC; Department of Dentistry, Oral Medicine Center, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC.
authors.forename: Chih-Yu
authors.initials: CY
authors.lastname: Peng
authors.affiliation: School of Dentistry, College of Oral Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC; Department of Dentistry, Oral Medicine Center, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC.
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Huang
authors.affiliation: School of Dentistry, College of Oral Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC; Department of Dentistry, Oral Medicine Center, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC.
authors.forename: Ming-Yi
authors.initials: MY
authors.lastname: Lu
authors.affiliation: School of Dentistry, College of Oral Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC; Department of Dentistry, Oral Medicine Center, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC.
authors.forename: Yu-Hsien
authors.initials: YH
authors.lastname: Lee
authors.affiliation: School of Dentistry, College of Oral Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC; Department of Dentistry, Oral Medicine Center, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC. Electronic address: tao2008@csmu.edu.tw.
authors.forename: Chuan-Hang
authors.initials: CH
authors.lastname: Yu
mesh_terms: D000368:Aged; D018289:Carcinoma, Verrucous / Q000473:pathology* / Q000601:surgery; D003803:Dentigerous Cyst / Q000150:complications* / Q000601:surgery; D004848:Epithelium / Q000473:pathology*; D006801:Humans; D008297:Male; D009808:Odontogenic Tumors / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014095:Tooth, Impacted / Q000000981:diagnostic imaging*
keywords: dentigerous cyst; intraosseous verrucous carcinoma; odontogenic cyst