title: A comparison of respiratory and peripheral muscle strength, functional exercise capacity, activities of daily living and physical fitness in patients with cystic fibrosis and healthy subjects.
abstract: There are limited reports that compare muscle strength, functional exercise capacity, activities of daily living (ADL) and parameters of physical fitness of cystic fibrosis (CF) patients with healthy peers in the literature. The purpose of this study was to assess and compare respiratory and peripheral muscle strength, functional exercise capacity, ADL and physical fitness in patients with CF and healthy subjects. Nineteen patients with CF (mean forced expiratory volume in one second-FEV1: 86.56±18.36%) and 20 healthy subjects were included in this study. Respiratory (maximal inspiratory pressure-MIP and maximal expiratory pressure-MEP) and peripheral muscle strength (quadriceps, shoulder abductors and hand grip strength) were evaluated. Functional exercise capacity was determined with 6min walk test (6MWT). ADL was assessed with Glittre ADL test and physical fitness was assessed with Munich fitness test (MFT). There were not any statistically significant difference in MIP, %MIP, MEP and %MEP values between two groups (p>0.05). %Peripheral muscle strength (% quadriceps and shoulder abductors strength), 6MWT distance and %6MWT distance were significantly lower in patients with CF than those of healthy subjects (p<0.05). Glittre ADL-test time was significantly longer in patients with CF than healthy subjects (p<0.05). According to Munich fitness test, the number of bouncing a ball, hanging score, distance of standing vertical jumping and standing vertical jumping score were significantly lower in patients with CF than those of healthy subjects (p<0.05). Peripheral muscle strength, functional exercise capacity, ADL performance and speed, coordination, endurance and power components of physical fitness are adversely affected in mild-severe patients with CF compared to healthy peers. Evaluations must be done in comprehensive manner in patients with CF with all stages.
authors.affiliation: Hacettepe University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, 06100 Samanpazari, Ankara, Turkey.
authors.forename: Hulya
authors.initials: H
authors.lastname: Arikan
authors.affiliation: Dogu Akdeniz University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Gazimagusa, Cyprus.
authors.forename: İlker
authors.initials: İ
authors.lastname: Yatar
authors.affiliation: Hacettepe University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, 06100 Samanpazari, Ankara, Turkey. Electronic address: ebrucalk85@hotmail.com.
authors.forename: Ebru
authors.initials: E
authors.lastname: Calik-Kutukcu
authors.affiliation: Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Besevler, Ankara, Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Aribas
authors.affiliation: Hacettepe University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, 06100 Samanpazari, Ankara, Turkey.
authors.forename: Melda
authors.initials: M
authors.lastname: Saglam
authors.affiliation: Hacettepe University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, 06100 Samanpazari, Ankara, Turkey.
authors.forename: Naciye
authors.initials: N
authors.lastname: Vardar-Yagli
authors.affiliation: Dokuz Eylül University, School of Physiotherapy and Rehabilitation, 35340 Inciralti, Izmir, Turkey.
authors.forename: Sema
authors.initials: S
authors.lastname: Savci
authors.affiliation: Hacettepe University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, 06100 Samanpazari, Ankara, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Inal-Ince
authors.affiliation: Hacettepe University, Faculty of Medicine, Department of Child Health and Diseases, Unit of Chest Diseases, 06230 Sihhiye, Ankara, Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Ozcelik
authors.affiliation: Hacettepe University, Faculty of Medicine, Department of Child Health and Diseases, Unit of Chest Diseases, 06230 Sihhiye, Ankara, Turkey.
authors.forename: Nural
authors.initials: N
authors.lastname: Kiper
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D003550:Cystic Fibrosis / Q000503:physiopathology*; D005080:Exercise Test; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D005541:Forced Expiratory Volume; D018737:Hand Strength; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D053580:Muscle Strength / Q000502:physiology*; D018482:Muscle, Skeletal / Q000503:physiopathology; D010809:Physical Fitness / Q000502:physiology*; D052097:Quadriceps Muscle / Q000503:physiopathology*; D012132:Respiratory Muscles / Q000503:physiopathology*; D055815:Young Adult
keywords: Cystic fibrosis; Daily living activities; Endurance; Exercise; Fitness; Muscle; Respiratory muscle; Strength