title: Total Hip Arthroplasty in Systemic Lupus Erythematosus: A Systematic Review.
abstract: The prognosis of systemic lupus erythematosus (SLE) has greatly improved in recent years, resulting in an increased number of patients reporting musculoskeletal complications such as osteonecrosis of the femoral head. Total hip arthroplasty (THA) can be utilised to alleviate the pain associated with this; however postoperative outcomes in patients with SLE are uncertain. A systematic review of the literature was conducted to identify articles presenting results of THA in SLE, and nine suitable papers were found. All papers were level IV evidence. Pooling the results, a total of 162 patients underwent 214 total hip arthroplasties. Mean follow-up was 72.5 months. The mean Harris Hip Score improved from 45.5 preoperatively to 88.6 and last follow-up. Seventeen percent of patients experienced at least one complication. Superficial wound infection occurred in 3.3%. Revision was required in 2.8% of cases. The mortality rate was 18.5% however no deaths were attributable to undergoing THA. Given the paucity of data present in the literature, more studies are required to adequately assess the postoperative outcomes of THA in patients with SLE, particularly complication rates.
authors.affiliation: Department of Trauma and Orthopaedics, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, UK.|University of Glasgow, Glasgow G12 8QQ, UK.
authors.forename: Ian W
authors.identifier: 0000-0003-3019-3360
authors.initials: IW
authors.lastname: Kennedy
authors.affiliation: University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthpaedic Hospital, Stanmore HA7 4LP, UK.
authors.forename: Wasim
authors.initials: W
authors.lastname: Khan