title: The Emerging Role of Metalloproteomics in Alzheimer's Disease Research.
abstract: Metals are increasingly recognized to have an important role in molecular processes underlying Alzheimer's disease (AD). This chapter discusses the current role of metals in AD and expands on the development of metalloproteomics and how the recent advances in analytical technology will allow detailed investigation of metalloproteins. Investigation of individual metalloproteins will yield new mechanistic details about the role of metals in AD.
authors.affiliation: The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, 30 Royal Parade, Parkville, VIC, 3052, Australia.
authors.forename: Dominic J
authors.initials: DJ
authors.lastname: Hare
authors.forename: Alan
authors.initials: A
authors.lastname: Rembach
authors.forename: Blaine R
authors.initials: BR
authors.lastname: Roberts
mesh_terms: D000544:Alzheimer Disease / Q000378:metabolism*; D000818:Animals; D006801:Humans; D008667:Metalloproteins / Q000378:metabolism*; D019216:Metals, Heavy / Q000378:metabolism; D040901:Proteomics / Q000379:methods*
chemical_list: D008667:Metalloproteins; D019216:Metals, Heavy