title: [Effect of lumbar (perirenal) procaine blockade on microcirculation and exchange proteoglycans with experimental gonarthrosis].
abstract: Experimental studies on guinea pigs of both sexes (n = 30). Experimental animals are awicea into equal groups oJ 10 animals: 1--the control group (intact animals), 2--the comparison group (modelling of gonarthrosis by crossing his own patellar ligament has been made, exposure 6 months), 3--the main group (animals with gonarthrosis treatment was carried out by performing lumbar procaine blockade (LPB) with an interval of 3-5 days three times). We establish that after a course of LPB in gonarthrosis marked increase in the density of the injected channel in the articular and periarticular structures, which reflects a growth in the microcirculation, and more intense accumulation in the basic substance of epiphyseal cartilage PAS (+) indicates the material to increase the level of proteoglycan in articular cartilage.
authors.forename: A D
authors.initials: AD
authors.lastname: Tarasko
authors.forename: I A
authors.initials: IA
authors.lastname: Ibatullin
authors.forename: A K
authors.initials: AK
authors.lastname: Aref'eva
mesh_terms: D000775:Anesthesia, Spinal; D000779:Anesthetics, Local / Q000494:pharmacology*; D000818:Animals; D002358:Cartilage, Articular / Q000098:blood supply / Q000378:metabolism / Q000473:pathology; D005260:Female; D006168:Guinea Pigs; D008297:Male; D008833:Microcirculation / Q000187:drug effects*; D010003:Osteoarthritis / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D011343:Procaine / Q000494:pharmacology*; D011509:Proteoglycans / Q000378:metabolism*
chemical_list: D000779:Anesthetics, Local; D011509:Proteoglycans; D011343:Procaine