title: Characteristics of Three-Dimensional Power Doppler in Gestational Trophoblastic Disease.
abstract: OBJECTIVE
  In the present study, the three-dimensional power Doppler was used as a quantitative method to evaluate its reliability in detecting and assessing of gestational trophoblastic disease (GTD).
  
  
  METHODS
  52 GTD patients who received diagnosis and treatment at the first affiliated hospitals of Xi'an Jiaotong University in China between 2011 and 2013 were evaluated using Voluson E8 (GE Medical System). Demographic information, pathological characteristics, clinical history, sonographic images, and related indices (resistance index, vascularization index, and flow and vascularization index) were evaluated.
  
  
  RESULTS
  Three-dimension power Doppler indicated that there were significant differences in the resistance index, vascularization index, flow index, and vascularization-flow index between the healthy individuals and each subgroup of patients (P < 0.01). Further, in combining invasive hydatidiform mole and choriocarcinoma groups, there was a significant difference between hydatidiform mole and the combined malignant group (P < 0.01). And the abnormal sonographic and power Doppler findings in GTD were resolved when chemotherapy was done successfully.
  
  
  CONCLUSIONS
  Combined with the clinical features, sonography and three-dimension power Doppler imaging were helpful in diagnosing GTD as a noninvasive method, distinguishing the invasive nature of disease, detecting the recurrence of the disease, and assessing the effectiveness of the chemotherapy.
authors.affiliation: Obstetrics and Gynecology Department, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.affiliation: Obstetrics and Gynecology Department, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Xueye
authors.initials: X
authors.lastname: Tian
authors.affiliation: Obstetrics and Gynecology Department, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Obstetrics and Gynecology Department, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Obstetrics and Gynecology Department, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Han
authors.affiliation: Obstetrics and Gynecology Department, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Ruifang
authors.initials: R
authors.lastname: An
mesh_terms: D000328:Adult; D019560:Echocardiography, Three-Dimensional; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D018608:Ultrasonography, Doppler