title: Tissue plasminogen activator treatment of bilateral pulmonary emboli in a pediatric patient supported with a ventricular assist device.
abstract: Bleeding and thrombosis are well-known potential complications of VAD support. We present a pediatric patient who developed massive bilateral pulmonary emboli while on BiVAD support that was successfully treated with intravenous tPA and bridged to heart transplant.
authors.affiliation: Division of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
authors.forename: Justin
authors.initials: J
authors.lastname: Godown
authors.affiliation: Division of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
authors.forename: Debra A
authors.initials: DA
authors.lastname: Dodd
authors.affiliation: Division of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Doyle
authors.affiliation: Division of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.|Division of Pediatric Critical Care, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
authors.forename: Andrew H
authors.initials: AH
authors.lastname: Smith
authors.affiliation: Division of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
authors.forename: Dana
authors.initials: D
authors.lastname: Janssen
authors.affiliation: Division of Cardiac Surgery, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
authors.forename: Bret A
authors.initials: BA
authors.lastname: Mettler
mesh_terms: D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006333:Heart Failure / Q000150:complications / Q000628:therapy*; D016027:Heart Transplantation; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008297:Male; D011655:Pulmonary Embolism / Q000188:drug therapy* / Q000209:etiology; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator
keywords: pediatric heart transplant; pulmonary embolism; ventricular assist device