title: An EQ-5D-5L value set based on Uruguayan population preferences.
abstract: OBJECTIVE
  To derive a value set from Uruguayan general population using the EQ-5D-5L questionnaire and report population norms.
  
  
  METHODS
  General population individuals were randomly assigned to value 10 health states using composite time trade off and 7 pairs of health states through discrete choice experiments. A stratified sampling with quotas by location, gender, age and socio-economic status was used to respect the Uruguayan population structure. Trained interviewers conducted face-to-face interviews. The EuroQol valuation technology was used to administer the protocol as well as to collect the data. OLS and maximum likelihood robust regression models with or without interactions were tested.
  
  
  RESULTS
  We included 794 respondents between 20 and 83 years. Their characteristics were broadly similar to the Uruguayan population. The main effects robust model was chosen to derive social values. Values ranged from -0.264 to 1. States with a misery index = 6 had a mean predicted value of 0.965. When comparing the Uruguayan population with the Argentinian EQ-5D-5L crosswalk value set, the prediction for states which differed from full health only in having one of the dimensions at level 2 were about 0.05 higher in Uruguay. The mean index value, using the selected Uruguayan EQ-5D-5L value set, for the general population in Uruguay was 0.895. In general, older people had worse values and males had slightly better values than females.
  
  
  CONCLUSIONS
  We derived the EQ-5D-5L Uruguayan value set, the first in Latin America. These results will help inform decision-making using economic evaluations for resource allocation decisions.
authors.affiliation: Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina.|Escuela de Salud Pública, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
authors.forename: Federico
authors.initials: F
authors.lastname: Augustovski
authors.affiliation: Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina.
authors.forename: Lucila
authors.initials: L
authors.lastname: Rey-Ares
authors.affiliation: Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina.
authors.forename: Vilma
authors.initials: V
authors.lastname: Irazola
authors.affiliation: Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina.
authors.forename: Osvaldo Ulises
authors.initials: OU
authors.lastname: Garay
authors.affiliation: Fondo Nacional de Recursos, Montevideo, Uruguay.
authors.forename: Oscar
authors.initials: O
authors.lastname: Gianneo
authors.affiliation: Fondo Nacional de Recursos, Montevideo, Uruguay.
authors.forename: Graciela
authors.initials: G
authors.lastname: Fernández
authors.affiliation: Fondo Nacional de Recursos, Montevideo, Uruguay.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Morales
authors.affiliation: Instituto de Efectividad Clínica y Sanitaria (IECS), Buenos Aires, Argentina.
authors.forename: Luz
authors.initials: L
authors.lastname: Gibbons
authors.affiliation: The EuroQol Research Foundation, Rotterdam, The Netherlands. juanmanuel.ramosgoni@gmail.com.|Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), C/Calvario, 271, 1ª IZQ, 38350, Tacoronte, Tenerife, Spain. juanmanuel.ramosgoni@gmail.com.
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Ramos-Goñi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012016:Reference Values; D011795:Surveys and Questionnaires; D014583:Uruguay; D055815:Young Adult
keywords: EuroQol; Preferences; Quality of life; Uruguay; Value set