title: Impact of obesity on autonomic modulation, heart rate and blood pressure in obese young people.
abstract: BACKGROUND
  Obesity can be understood as a comorbidity of increasing systemic impact, including a deficit in the autonomic nervous system.
  
  
  OBJECTIVE
  To analyze cardiac autonomic behavior and hemodynamic parameters in obese young people.
  
  
  METHODS
  92 individuals (20.58±1.48 years) were evaluated, divided into two groups: obese and eutrophic. Heart rate (HR) was captured for 30 min in the supine position whilst breathing spontaneously. Blood pressure (BP) values were obtained prior to performance of the protocol. For the autonomic analysis, 1000 beats were used for the calculation of heart rate variability indices in the time (Mean RR, SDNN and RMSSD) and frequency (LF, HF and LF/HF) domains, in addition to the Poincaré plot (SD1, SD2, SD1/SD2 and qualitative visual analysis).
  
  
  RESULTS
  The obese group presented higher baseline BP and HR values compared to the eutrophic. Regarding autonomic modulation a significant decrease was observed in the RMSSD; SD1, HFms and HFnu indices in the obese group, indicating a decrease in vagal activity and reduced SDNN and SD2 rates, with statistical significance for the former, suggesting a reduction in overall variability. The high value of the LFnu index and decrease in Mean RR in the obese group pointed to relative sympathetic predominance in these individuals. The visual analysis of the Poincaré plot showed less dispersion of the points in the obese group.
  
  
  CONCLUSIONS
  The obese group presented higher BP and HR values at rest and autonomic impairment, characterized by a reduction in parasympathetic activity and relative predominance of sympathetic activity.
authors.affiliation: Faculty of Medicine in ABC - FMABC, Santo André, SP, Brazil. Electronic address: rclarossi@gmail.com.
authors.forename: Renata Claudino
authors.initials: RC
authors.lastname: Rossi
authors.affiliation: Department of Physical Therapy, Faculty of Science and Technology - FCT/UNESP, Presidente Prudente, SP, Brazil.
authors.forename: Luiz Carlos Marques
authors.initials: LC
authors.lastname: Vanderlei
authors.affiliation: Department of Physical Therapy, Faculty of Science and Technology - FCT/UNESP, Presidente Prudente, SP, Brazil.
authors.forename: Ana Clara Campagnolo Real
authors.initials: AC
authors.lastname: Gonçalves
authors.affiliation: Department of Physical Therapy, Faculty of Science and Technology - FCT/UNESP, Presidente Prudente, SP, Brazil.
authors.forename: Franciele Marques
authors.initials: FM
authors.lastname: Vanderlei
authors.affiliation: Faculty of Medicine in ABC - FMABC, Santo André, SP, Brazil.
authors.forename: Aline Fernanda Barbosa
authors.initials: AF
authors.lastname: Bernardo
authors.affiliation: Faculty of Science and Technology - FCT/UNESP, Presidente Prudente, SP, Brazil.
authors.forename: Karina Mayumi Higashibara
authors.initials: KM
authors.lastname: Yamada
authors.affiliation: Faculty of Science and Technology - FCT/UNESP, Presidente Prudente, SP, Brazil.
authors.forename: Natália Turri
authors.initials: NT
authors.lastname: da Silva
authors.affiliation: Faculty of Medicine in ABC - FMABC, Santo André, SP, Brazil.
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: de Abreu
mesh_terms: D001341:Autonomic Nervous System / Q000503:physiopathology*; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D016014:Linear Models; D008297:Male; D008991:Monitoring, Physiologic; D009765:Obesity / Q000503:physiopathology*; D012146:Rest; D055815:Young Adult
keywords: Autonomic nervous system; Cardiology; Heart rate; Obesity