title: [Impact of Geriatric Drug Guidelines on the Quality Requirement of Elderly Patients].
abstract: OBJECTIVE
  Elderly with several pathologies are usually treated with many drugs, and are exposed to a majored risk of drug-induced adverse effects. A network of local nursing homes (EHPAD) in the south Seine-Saint-Denis area (France) created a geriatric drug guidelines to improve the quality of the drugs prescriptions. This study assesses the conformity of prescriptions in elderly patients prior and after the distribution of the booklet.
  
  
  METHODS
  This before and after design study focused on the drug prescriptions for patients in eight EHPAD followed for two randomly given days in 2012 (n = 503) and 2013 (n = 334). The geriatric drug guidelines included a list of medicines suitable for the elderly (conformity list) and recommendations for prescription and monitoring. Data collection was conducted from medical records and interviews with coordinators doctors and nursing staff in nursing homes. A 6 items-quality score was calculated, ranging from 0 (lowest quality) to 6 (highest quality).
  
  
  RESULTS
  Median age, weight and creatinine level were respectively 88 years, 61.0 kg, and 74.9 μmol/L (prior) and 88 years, 59.6 kg, and 77.0 μmol/L (after). Median times of latest serum creatinine dosage were 112 days (prior) and 108 days (after). The median number of prescribed drugs was 8 per resident during the two period of study. The conformity rate of prescription was better prior the distribution of the guidelines, respectively 87.5% and 80.0% (p<10⁻³). The average formal quality score was better after the distribution of the booklet increasing form 4.23 to 4.40 points (p<10⁻⁴). For high risk inducing drugs, monitoring was prescribed in 34.2% (prior) and 32.4% (after).
  
  
  CONCLUSIONS
  This study shows that the drug geriatric guidelines does not improve prescription conformity and monitoring for high risk drugs, but it does significantly improve the median formal quality score.
authors.affiliation: Service Pharmacie, Groupe Hospitalier Le Raincy-Montfermeil, Montfermeil, France.
authors.forename: Francis
authors.initials: F
authors.lastname: Fauvelle
authors.affiliation: Service de Gériatrie, Groupe Hospitalier Le Raincy-Montfermeil, Montfermeil, France.
authors.forename: Fariba
authors.initials: F
authors.lastname: Kabirian
authors.affiliation: Service Pharmacie, Groupe Hospitalier Le Raincy-Montfermeil, Montfermeil, France.
authors.forename: Alison
authors.initials: A
authors.lastname: Domingues
authors.affiliation: AP-HP, Hôpital Bichat, Département Épidémiologique et Recherche Clinique, Paris, France - INSERM CIE 801, 75018 Paris, France - Université Paris Diderot, Sorbonne Paris-Cité Paris, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Tubach
authors.affiliation: AP-HP, Hôpital Bichat, Département Épidémiologique et Recherche Clinique, Paris, France - INSERM CIE 801, 75018 Paris, France - Université Paris Diderot, Sorbonne Paris-Cité Paris, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Gault
authors.affiliation: AP-HP, Hôpital Bichat, Département Épidémiologique et Recherche Clinique, Paris, France - INSERM CIE 801, 75018 Paris, France - Université Paris Diderot, Sorbonne Paris-Cité Paris, France.
authors.forename: Rachid
authors.initials: R
authors.lastname: Abbas
mesh_terms: D000368:Aged / Q000523:psychology*; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism; D003404:Creatinine / Q000097:blood; D004347:Drug Interactions; D016903:Drug Monitoring; D011307:Drug Prescriptions / Q000592:standards*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000517:prevention & control; D004502:Education, Medical, Continuing / Q000379:methods*; D005851:Geriatric Nursing; D005853:Geriatrics; D019538:Health Care Surveys; D006801:Humans; D057970:Inappropriate Prescribing / Q000517:prevention & control; D008499:Medical Records; D055118:Medication Adherence; D009735:Nursing Homes; D010174:Pamphlets; D019338:Polypharmacy; D000067561:Potentially Inappropriate Medication List; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards* / Q000706:statistics & numerical data; D011785:Quality Assurance, Health Care / Q000592:standards; D012494:Sampling Studies
chemical_list: D003404:Creatinine