title: [Autoimmune enteropathy].
abstract: Autoimmune enteropathy (AIE) is characterized by protracted diarrhea, malabsorption, immunomediated damage to the intestinal mucosa, and unresponsiveness to changes in diet. The disease is mainly manifested in the small intestine. Lymphocyte deposits are present on the mucous membrane, and anti-enterocyte or anti-goblet cell antibodies have been described in the majority of affected persons. AIE occurs primarily in infants. Immunosuppressive drugs have been used with varying success. The prognosis of AlE is dependent on the degree of severity of the damage to the intestinal mucosa and extraintestinal symptoms and diseases associated therewith.
authors.forename: Urpo
authors.initials: U
authors.lastname: Kinnunen
authors.forename: Katri
authors.initials: K
authors.lastname: Vuopala
authors.forename: Katri
authors.initials: K
authors.lastname: Kaukinen
mesh_terms: D001327:Autoimmune Diseases / Q000276:immunology / Q000473:pathology / Q000517:prevention & control*; D003967:Diarrhea / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007413:Intestinal Mucosa / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology*; D008286:Malabsorption Syndromes / Q000276:immunology / Q000473:pathology / Q000517:prevention & control*; D011379:Prognosis; D012307:Risk Factors
chemical_list: D007166:Immunosuppressive Agents