title: Centrosome biology: the ins and outs of centrosome assembly.
abstract: As a microtubule-organizing center, the centrosome undergoes a dramatic increase in size - via expansion of the pericentriolar material - during mitosis. Recent work reveals shared assembly properties of a protein scaffold that facilitates and supports this expansion, a process critical to spindle assembly.
authors.affiliation: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada.
authors.forename: Suzanna L
authors.initials: SL
authors.lastname: Prosser
authors.affiliation: Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, M5S 1A8, Canada. Electronic address: pelletier@lunenfeld.ca.
authors.forename: Laurence
authors.initials: L
authors.lastname: Pelletier
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics*; D029742:Caenorhabditis elegans Proteins / Q000235:genetics*; D018797:Cell Cycle Proteins / Q000235:genetics*; D018385:Centrosome / Q000378:metabolism*; D004330:Drosophila / Q000235:genetics*
chemical_list: D029742:Caenorhabditis elegans Proteins; D018797:Cell Cycle Proteins; C000598471:SPD-5 protein, C elegans