title: Languages and dialects: bacterial communication beyond homoserine lactones.
abstract: Gram-negative bacteria use N-acyl homoserine lactones (acyl-HSLs) for communication, predominantly mediated by LuxR-type receptors. Recent studies uncovered aryl-HSLs, α-pyrones and dialkylresorcinols as further chemical languages of Gram-negative bacteria. These findings extend the number of bacterial signaling molecules and suggest that cell-cell communication goes far beyond acyl-HSL signaling in nature.
authors.affiliation: Ludwig-Maximilians-Universität München, Biozentrum, Bereich Mikrobiologie, Großhaderner Str. 2-4, 82152 Martinsried/München, Germany.
authors.forename: Sophie
authors.initials: S
authors.lastname: Brameyer
authors.affiliation: Goethe-Universität Frankfurt, Biozentrum, Merck-Stiftungsprofessur für Molekulare Biotechnologie, Fachbereich Biowissenschaften, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany; Buchmann Institute for Molecular Life Sciences (BMLS), Goethe-Universität Frankfurt, 60438 Frankfurt am Main, Germany.
authors.forename: Helge B
authors.initials: HB
authors.lastname: Bode
authors.affiliation: Ludwig-Maximilians-Universität München, Biozentrum, Bereich Mikrobiologie, Großhaderner Str. 2-4, 82152 Martinsried/München, Germany. Electronic address: heermann@lmu.de.
authors.forename: Ralf
authors.initials: R
authors.lastname: Heermann
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000378:metabolism; D054742:Acyl-Butyrolactones / Q000378:metabolism; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000502:physiology*; D020637:Photorhabdus / Q000502:physiology; D053038:Quorum Sensing; D012097:Repressor Proteins / Q000378:metabolism; D015398:Signal Transduction; D015534:Trans-Activators / Q000378:metabolism
chemical_list: D054742:Acyl-Butyrolactones; D001426:Bacterial Proteins; D012097:Repressor Proteins; D015534:Trans-Activators; C064778:LuxR autoinducer binding proteins; C088386:homoserine lactone; D015107:4-Butyrolactone
keywords: LuxR solos; Photorhabdus; aryl-HSL; dialkylresorcinols; photopyrones; quorum sensing