title: [COMPARATIVE EVALUATION OF SURGICAL APPROACHES TO TREATMENT OF PATIENTS WITH SKIN MELANOMA].
abstract: In recent years there has been rapid growth in the incidence of melanoma. Due to the large number of patients with various pigmented lesions, suspicious for melanoma, requiring differential diagnosis there is an actual problem of excisional biopsy in this group of patients. This review extensively covered approaches to radical surgical treatment of patients with skin melanoma. There are described in detail results of the studies of foreign experts regarding the influence of excisional and incisional biopsy on overall and disease-free survival rates of patients. On a large representative material (1126 patients) there are widely reflected the results of our studies to assess the effect of different surgical approaches to treatment of patients with skin melanoma. At present the authors can not recommend to perform excisional biopsy of patients with primary skin melanoma in oncological practice. Obviously for a final resolution of this problem it is necessary to conduct a multicenter randomized trial.
authors.forename: V V
authors.initials: VV
authors.lastname: Anisimov
authors.forename: Yu V
authors.initials: YV
authors.lastname: Semiletova
authors.forename: G I
authors.initials: GI
authors.lastname: Gafton
authors.forename: V G
authors.initials: VG
authors.lastname: Lemekhov
authors.forename: M Yu
authors.initials: MY
authors.lastname: Myasnyankin
authors.forename: I G
authors.initials: IG
authors.lastname: Gafton
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D057186:Comparative Effectiveness Research; D003937:Diagnosis, Differential; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008545:Melanoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D018365:Neoplasm, Residual / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome; D000096142:Cutaneous Malignant Melanoma