title: Encapsulated eucalyptus oil in ionically cross-linked alginate microcapsules and its controlled release.
abstract: Sodium alginate microcapsules containing eucalyptus oil were prepared by oil-in-water emulsification via Shirasu porous glass (SPG) membrane and cross-linked by calcium chloride (CaCl2). SPG membrane pore size of 5.2μm was used to control the size of eucalyptus oil microdroplets. Effects of sodium alginate, having a mannuronic acid/guluronic acid (M/G) ratio of 1.13, eucalyptus oil and CaCl2 amounts on microdroplet sizes and size distribution were elucidated. Increasing sodium alginate amounts from 0.1 to 0.5% (wv(-1)) sodium alginate, the average droplets size increased from 42.2±2.0 to 48.5±0.6μm, with CVs of 16.5±2.2 and 30.2±4.5%, respectively. CaCl2 successfully gave narrower size distribution of cross-linked eucalyptus oil microcapsules. The optimum conditions for preparing the microcapsules, oil loading efficiency, and controlled release of the encapsulated eucalyptus oil from the microcapsules as a function of time at 40°C were investigated. Release model for the oil from microcapsules fitted Ritger-Peppas model with non-Fickian transport mechanism.
authors.affiliation: Department of Imaging and Printing Technology, Faculty of Science, Chulalongkorn University, 254 Phayathai Road, Patumwan, Bangkok 10330, Thailand. Electronic address: Supaporn.N@Chula.ac.th.
authors.forename: Supaporn
authors.initials: S
authors.lastname: Noppakundilograt
authors.affiliation: Program of Petrochemistry and Polymer Science, Faculty of Science, Chulalongkorn University, 254 Phayathai Road, Patumwan, Bangkok 10330, Thailand. Electronic address: be_pupu119@hotmail.com.
authors.forename: Phianghathai
authors.initials: P
authors.lastname: Piboon
authors.affiliation: Program of Petrochemistry and Polymer Science, Faculty of Science, Chulalongkorn University, 254 Phayathai Road, Patumwan, Bangkok 10330, Thailand. Electronic address: porn_grai@yahoo.com.
authors.forename: Wilaiporn
authors.initials: W
authors.lastname: Graisuwan
authors.affiliation: Department of Environmental Science, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: Roongkan.N@Chula.ac.th.
authors.forename: Roongkan
authors.initials: R
authors.lastname: Nuisin
authors.affiliation: Department of Imaging and Printing Technology, Faculty of Science, Chulalongkorn University, 254 Phayathai Road, Patumwan, Bangkok 10330, Thailand; Academy of Sciences, the Royal Society of Thailand, Sanam Sueapa, Dusit, Bangkok 10300, Thailand. Electronic address: ksuda@chula.ac.th.
authors.forename: Suda
authors.initials: S
authors.lastname: Kiatkamjornwong
mesh_terms: D000464:Alginates / Q000737:chemistry*; D002118:Calcium / Q000032:analysis; D002122:Calcium Chloride / Q000032:analysis; D002214:Capsules; D003432:Cross-Linking Reagents / Q000737:chemistry*; D003692:Delayed-Action Preparations; D004655:Emulsions; D005052:Eucalyptus / Q000737:chemistry*; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D007477:Ions; D007700:Kinetics; D008855:Microscopy, Electron, Scanning; D010316:Particle Size; D010938:Plant Oils / Q000737:chemistry*; D066244:Proton Magnetic Resonance Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000464:Alginates; D002214:Capsules; D003432:Cross-Linking Reagents; D003692:Delayed-Action Preparations; D004655:Emulsions; D006603:Hexuronic Acids; D007477:Ions; D010938:Plant Oils; D020723:Glucuronic Acid; D002122:Calcium Chloride; D002118:Calcium
keywords: Alginate; Calcium chloride; Calcium chloride (PubChem CID: 21226093); Controlled release; Eucalyptus oil; Eucalyptus oil (PubChem CID: 2758); Microcapsules; Poly(vinyl alcohol) (PubChem CID: 11199); Sodium alginate (PubChem CID: 6850754); Sodium dodecyl sulfate (PubChem CID: 3423265)