title: Cerebrospinal fluid concentrations of tenofovir and emtricitabine in the setting of HIV-1 protease inhibitor-based regimens.
authors.affiliation: Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Atlanta, GA, USA.
authors.forename: Cecile D
authors.initials: CD
authors.lastname: Lahiri
authors.affiliation: University of Alabama-Birmingham School of Medicine, Department of Pharmacology and Toxicology, Division of Clinical Pharmacology, Birmingham, AL, USA.
authors.forename: Kedria
authors.initials: K
authors.lastname: Reed-Walker
authors.affiliation: Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Atlanta, GA, USA.
authors.forename: Anandi N
authors.initials: AN
authors.lastname: Sheth
authors.affiliation: University of Alabama-Birmingham School of Medicine, Department of Pharmacology and Toxicology, Division of Clinical Pharmacology, Birmingham, AL, USA.
authors.forename: Edward P
authors.initials: EP
authors.lastname: Acosta
authors.affiliation: Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Atlanta, GA, USA.
authors.forename: Aswani
authors.initials: A
authors.lastname: Vunnava
authors.affiliation: Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, Atlanta, GA, USA.
authors.forename: Ighovwerha
authors.initials: I
authors.lastname: Ofotokun
mesh_terms: D019380:Anti-HIV Agents / Q000134:cerebrospinal fluid* / Q000627:therapeutic use; D001812:Blood-Brain Barrier / Q000378:metabolism; D002555:Cerebrospinal Fluid / Q000378:metabolism* / Q000821:virology; D000068679:Emtricitabine / Q000134:cerebrospinal fluid* / Q000627:therapeutic use; D005260:Female; D016333:HIV Protease / Q000378:metabolism*; D017320:HIV Protease Inhibitors / Q000134:cerebrospinal fluid / Q000627:therapeutic use*; D015497:HIV-1 / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D011355:Prodrugs / Q000627:therapeutic use; D012367:RNA, Viral / Q000134:cerebrospinal fluid; D000068698:Tenofovir / Q000134:cerebrospinal fluid* / Q000627:therapeutic use
chemical_list: D019380:Anti-HIV Agents; D017320:HIV Protease Inhibitors; D011355:Prodrugs; D012367:RNA, Viral; D000068698:Tenofovir; D016333:HIV Protease; C514803:p16 protease, Human immunodeficiency virus 1; D000068679:Emtricitabine
keywords: HIV/AIDS; central nervous system; clinical pharmacology