title: Palladium(II)-catalysed regioselective synthesis of 3,4-disubstituted quinolines and 2,3,5-trisubstituted pyrroles from alkenes via anti-Markovnikov selectivity.
abstract: A novel strategy has been identified for the regioselective synthesis of 3,4-disubstituted quinolines and 2,3,5-trisubstituted pyrroles from simple alkenes via anti-Markovnikov selectivity under palladium catalysis. The salient features are synthesis of two different heterocycles, readily available starting materials, broad substrate scope, moderate to good yields and use of molecular oxygen as a terminal oxidant.
authors.affiliation: Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, No. 100, Shiquan 1st Rd, Sanmin District, Kaohsiung City 807, Taiwan. jjwang@kmu.edu.tw.
authors.forename: Gopal Chandru
authors.initials: GC
authors.lastname: Senadi
authors.forename: Wan-Ping
authors.initials: WP
authors.lastname: Hu
authors.forename: Amol Milind
authors.initials: AM
authors.lastname: Garkhedkar
authors.forename: Siva Senthil Kumar
authors.initials: SS
authors.lastname: Boominathan
authors.forename: Jeh-Jeng
authors.initials: JJ
authors.lastname: Wang
mesh_terms: D000475:Alkenes / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D007536:Isomerism; D008956:Models, Chemical; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis*; D011804:Quinolines / Q000138:chemical synthesis*
chemical_list: D000475:Alkenes; D011758:Pyrroles; D011804:Quinolines; D010165:Palladium