title: Ultrafast Spreading Effect Induced Rapid Cell Trapping into Porous Scaffold with Superhydrophilic Surface.
abstract: In this contribution, superhydrophilic chitosan-based scaffolds with ultrafast spreading property were fabricated and used to improve the trapped efficiency of cells. The ultrafast spreading property allowed cells to be trapped into the internal 3D porous structures of the prepared scaffolds more quickly and effectively. Cell adhesion, growth, and proliferation were also improved, which could be attributed to the combination of UV irradiation and ultrafast spreading property. The construction of ultrafast spreading property on the scaffold surface will offer a novel way to design more effective scaffold in tissue engineering that could largely shorten the therapeutic time for patients.
authors.affiliation: ‡The State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130023, P. R. China.
authors.forename: Chenmiao
authors.initials: C
authors.lastname: Wang
authors.affiliation: §Department of Pathology, School of Stomatology, Jilin University, Changchun, P. R. China.
authors.forename: Chunyan
authors.initials: C
authors.lastname: Qiao
authors.affiliation: ‡The State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130023, P. R. China.
authors.forename: Wenlong
authors.initials: W
authors.lastname: Song
authors.affiliation: §Department of Pathology, School of Stomatology, Jilin University, Changchun, P. R. China.
authors.forename: Hongchen
authors.initials: H
authors.lastname: Sun
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D002448:Cell Adhesion / Q000187:drug effects; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D048271:Chitosan / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D039823:Iridoids / Q000737:chemistry; D051379:Mice; D008855:Microscopy, Electron, Scanning; D056951:Photoelectron Spectroscopy; D016062:Porosity; D013499:Surface Properties; D023822:Tissue Engineering; D054457:Tissue Scaffolds; D014466:Ultraviolet Rays
chemical_list: D001672:Biocompatible Materials; D039823:Iridoids; D048271:Chitosan; C007834:genipin
keywords: cells trapping; scaffold; superhydrophilicity; tissue engineering; ultrafast spreading