title: [Guidelines of Czech Association for Thrombosis and Haemostasis of the Czech Medical Association of J. E. Purkyně for safety treatment with new oral anticoagulants (NOAC) - dabigatran etexilate, apixaban and rivaroxaban].
abstract: There are presently new oral anticoagulants (NOAC) for prevention and the treatment of thromboembolic diseases and they are registered in CZ. It concerns of orally direct inhibitors of thrombin (dabigatran etexilate), inhibitors of factor Xa (apixaban, rivaroxaban), respectively, with advantage of some properties not being seen in "classical" anticoagulants. In the use of new anticoagulants, however, are some problems - such as laboratory monitoring in urgent situations of effective treatment and the absence of specific antidote - resolved. The text below brings indications, dosage of the drugs, their elimination, follow-up of efficacy of the treatment or risk of the bleeding as well as the therapy of bleeding complications.Key words: apixaban - dabigatran etexilate - NOAC - rivaroxaban.
authors.forename: Jan
authors.initials: J
authors.lastname: Kvasnička
authors.forename: Miroslav
authors.initials: M
authors.lastname: Penka
authors.forename: Tomáš
authors.initials: T
authors.lastname: Kvasnička
authors.forename: Jana
authors.initials: J
authors.lastname: Michalcová
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Kudrnová
authors.forename: Ivana
authors.initials: I
authors.lastname: Malíková