title: Screening mammography-detected ductal carcinoma in situ: mammographic features based on breast cancer subtypes.
abstract: We evaluated the mammographic and histopathologic features of screening mammography-detected ductal carcinoma in situ (DCIS) based on the breast cancer subtypes determined by immunohistochemistry. A total of 94 patients with 94 screening mammography-detected DCIS were included in this study. Mammographically, human epidermal growth factor receptor 2 (HER2)-positive DCIS was more commonly associated with calcifications than estrogen receptor (ER)-positive and triple-negative DCIS (P=.003). Histopathologically, HER2-positive DCIS and triple-negative DCIS were associated with high nuclear grade (P ≤ .001) and comedo necrosis (P ≤ .001) than ER-positive DCIS.
authors.affiliation: Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine.
authors.forename: Mi Young
authors.initials: MY
authors.lastname: Kim
authors.affiliation: Department of Radiology, St.Paul's Hospital, Catholic University of Korea. Electronic address: hskimsph@catholic.ac.kr.
authors.forename: Hyeon Sook
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine.
authors.forename: Nami
authors.initials: N
authors.lastname: Choi
authors.affiliation: Department of Surgery, Konkuk University Medical Center, Konkuk University School of Medicine.
authors.forename: Jung-Hyun
authors.initials: JH
authors.lastname: Yang
authors.affiliation: Department of Surgery, Konkuk University Medical Center, Konkuk University School of Medicine.
authors.forename: Young Bum
authors.initials: YB
authors.lastname: Yoo
authors.affiliation: Department of Surgery, Konkuk University Medical Center, Konkuk University School of Medicine.
authors.forename: Kyoung Sik
authors.initials: KS
authors.lastname: Park
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008327:Mammography; D008875:Middle Aged; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism; D012189:Retrospective Studies; D064726:Triple Negative Breast Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism
chemical_list: D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human
keywords: Breast; Calcification; ER; HER2; Mammography