title: The 10-year Absolute Risk of Cardiovascular (CV) Events in Northern Iran: a Population Based Study.
abstract: BACKGROUND
  The present study was conducted to estimate 10-year cardiovascular disease events (CVD) risk using three instruments in northern Iran.
  
  
  METHODS
  Baseline data of 3201 participants 40-79 of a population based cohort which was conducted in Northern Iran were analyzed. Framingham risk score (FRS), World Health Organization (WHO) risk prediction charts and American college of cardiovascular / American heart association (ACC/AHA) tool were applied to assess 10-year CVD events risk. The agreement values between the risk assessment instruments were determined using the kappa statistics.
  
  
  RESULTS
  Our study estimated 53.5%of male population aged 40-79 had a 10 -year risk of CVD events≥10% based on ACC/AHA approach, 48.9% based on FRS and 11.8% based on WHO risk charts. A 10 -year risk≥10% was estimated among 20.1% of women using the ACC/AHA approach, 11.9%using FRS and 5.7%using WHO tool. ACC/AHA and Framingham tools had closest agreement in the estimation of 10-year risk≥10% (κ=0.7757) in meanwhile ACC/AHA and WHO approaches displayed highest agreement (κ=0.6123) in women.
  
  
  CONCLUSIONS
  Different estimations of 10-year risk of CVD event were provided by ACC/AHA, FRS and WHO approaches.
authors.affiliation: Department of Social Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
authors.forename: Nima
authors.initials: N
authors.lastname: Motamed
authors.affiliation: Nuclear Medicine Department. Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Mardanshahi
authors.affiliation: Health Information Management, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Benyamin Mohseni
authors.initials: BM
authors.lastname: Saravi
authors.affiliation: School of Allied Medical Sciences, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Hasan
authors.initials: H
authors.lastname: Siamian
authors.affiliation: Gastrointestinal and Liver Disease Research Center, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Mansooreh
authors.initials: M
authors.lastname: Maadi
authors.affiliation: Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Farhad
authors.initials: F
authors.lastname: Zamani
keywords: 10-year cardiovascular risk; ACC/AHA tool; Framingham risk score; Northern Iran; WHO risk prediction charts