title: Fibrin glue versus autologous blood for conjunctival autograft fixation in pterygium surgery.
abstract: OBJECTIVE
  To compare the outcomes between autologous blood- and fibrin glue-fixated conjunctival autografts in pterygium excision surgery.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Forty eyes of 40 patients who had a primary nasal pterygium excision.
  
  
  METHODS
  A retrospective comparative case series of 40 eyes (40 patients) that had a primary nasal pterygium excision. All eyes had a conjunctival autograft from the superior bulbar conjunctiva to cover the scleral bed. Twenty eyes (20 patients) had fixation of the autograft using autologous blood (AB), and 20 eyes (20 patients) had fixation using fibrin glue (FG). One year of follow-up data included conjunctival graft stability (graft loss, graft retraction), pterygium recurrence, visual acuity, and postoperative complications. Descriptive and inferential statistics were performed.
  
  
  RESULTS
  Intraoperatively, no complications occurred in either group. Graft loss occurred in 6 patients in the AB group, compared with none in the FG group. Graft retraction occurred in 3 patients in the AB group and 2 patients in the FG group. At 1 year postoperatively, pterygium recurrence occurred in 4 patients in the AB group and 1 patient in the FG group. One patient in the AB group developed a small pyogenic granuloma that resolved by 6 months with conservative management. Visual acuity remained stable in both groups.
  
  
  CONCLUSIONS
  Conjunctival autograft fixation with autologous blood resulted in less stable conjunctival autografts and a higher recurrence rate compared with fixation with fibrin glue.
authors.affiliation: University of Ottawa, Ottawa, Ont.
authors.forename: Sophie
authors.initials: S
authors.lastname: Boucher
authors.affiliation: University of Ottawa, Ottawa, Ont.
authors.forename: Ronan
authors.initials: R
authors.lastname: Conlon
authors.affiliation: University of British Columbia, Vancouver, B.C.
authors.forename: Salina
authors.initials: S
authors.lastname: Teja
authors.affiliation: University of Ottawa, Ottawa, Ont.
authors.forename: Joshua C
authors.initials: JC
authors.lastname: Teichman
authors.affiliation: University of Ottawa, Ottawa, Ont.
authors.forename: Season
authors.initials: S
authors.lastname: Yeung
authors.affiliation: University of Ottawa, Ottawa, Ont.
authors.forename: Setareh
authors.initials: S
authors.lastname: Ziai
authors.affiliation: University of Ottawa, Ottawa, Ont. Electronic address: baig247@gmail.com.
authors.forename: Kashif
authors.initials: K
authors.lastname: Baig
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D064592:Autografts; D001769:Blood; D003228:Conjunctiva / Q000473:pathology / Q000637:transplantation*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006085:Graft Survival / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011625:Pterygium / Q000175:diagnosis / Q000601:surgery*; D012008:Recurrence; D012189:Retrospective Studies; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014182:Transplantation, Autologous; D014792:Visual Acuity / Q000502:physiology
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives