title: [IDPN: effects on the treatment of CKD-MBD].
abstract: In the population in hemodialysis a protein-calorie malnutrition is a frequent finding although of difficult evaluation, since the incidence of malnourished subjects is assessed between 35% and 60%, in relation to nutritional markers considered and their variability for reason related to uremia. Even in the management of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) is necessary the evaluation of the nutritional status of patients, and for a more correct assessment of clinical cases observed, both for the correct use of pharmacological treatement. The aim of this study is the evaluation of the most common parameters for the monitoring and of the nutritional status and the CKD-MBD induced by the use of intradialytic parenteral nutrition ( IDPN), for a period exceeding 12 months. The study raises the hypotesis that IDPN, by stimulating protein synthesis and reducing anorexia and inadeguate dietary behaviours in hemodialysis patients selected, in medium term, leads to a stable balance of serum calcium, phosphorus, PTH and alkaline phosphatase with modification of therapy in the treatement of CKD-MBD and a reduction dose of drugs. The changes made during the follow-up period to therapeutic means for the control of CKD-MBD emphasise the importance of evaluation of the nutritional status of the patient in order to use and adjust them correctly and, furthermore, how IDPN in cases of protein-calorie malnutrition may represents a suitable protection.
authors.forename: Maria
authors.initials: M
authors.lastname: Polidoro
mesh_terms: D000368:Aged; D001847:Bone Diseases / Q000150:complications; D006801:Humans; D010288:Parenteral Nutrition; D011502:Protein-Energy Malnutrition / Q000150:complications; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000150:complications / Q000628:therapy*