title: Validation of a Respiratory Symptom Questionnaire in Adolescent Smokers.
abstract: OBJECTIVE
  Adolescent smokers experience respiratory symptoms as a consequence of smoking, which may be impacted by harm-reduction products. We sought to validate the American Thoracic Society Questionnaire (ATSQ), a measure of respiratory symptoms, in adolescent smokers.
  
  
  METHODS
  Data were drawn from 2 studies of adolescents (ages 14 to 19). Study 1 (N = 118) comprised daily smokers. Study 2 (N = 216) comprised 118 smokers and 98 nonsmokers; a subset of the total sample comprised 70 matched pairs of smokers and non-smokers.
  
  
  RESULTS
  The ATSQ showed high internal consistency. In Study 1, ATSQ scores were positively correlated with dependence. In Study 2, scores were positively correlated with CO, cotinine, and cigarettes per day; and scores were significantly greater for smokers than non-smokers.
  
  
  CONCLUSIONS
  The ATSQ offers a psychometrically valid method for measuring respiratory symptoms in adolescent smokers.
authors.affiliation: Center for Alcohol and Addiction Studies, Brown University, Providence, RI.
authors.forename: Rachel N
authors.initials: RN
authors.lastname: Cassidy
authors.affiliation: Center of Excellence in Regulatory Tobacco Science, The Ohio State University, Columbus, OH.
authors.forename: Megan E
authors.initials: ME
authors.lastname: Roberts
authors.affiliation: Center for Alcohol and Addiction Studies, Brown University, Providence, RI.
authors.forename: Suzanne M
authors.initials: SM
authors.lastname: Colby
keywords: adolescents; methodology; respiratory symptoms; smoking