title: A new CT-based method to quantify radiation-induced lung damage in patients.
abstract: A new method to assess radiation-induced lung toxicity (RILT) using CT-scans was developed. It is more sensitive in detecting damage and corresponds better to physician-rated radiation pneumonitis than routinely-used methods. Use of this method may improve lung toxicity assessment and thereby facilitate development of more accurate predictive models for RILT.
authors.affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, The Netherlands; Department of Cell Biology, University Medical Center Groningen, University of Groningen, The Netherlands.
authors.forename: Ghazaleh
authors.initials: G
authors.lastname: Ghobadi
authors.affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, The Netherlands.
authors.forename: Erwin M
authors.initials: EM
authors.lastname: Wiegman
authors.affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, The Netherlands.
authors.forename: Johannes A
authors.initials: JA
authors.lastname: Langendijk
authors.affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, The Netherlands.
authors.forename: Joachim
authors.initials: J
authors.lastname: Widder
authors.affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, The Netherlands; Department of Cell Biology, University Medical Center Groningen, University of Groningen, The Netherlands.
authors.forename: Robert P
authors.initials: RP
authors.lastname: Coppes
authors.affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, The Netherlands; Department of Cell Biology, University Medical Center Groningen, University of Groningen, The Netherlands. Electronic address: p.van.luijk@umcg.nl.
authors.forename: Peter
authors.initials: P
authors.lastname: van Luijk
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008168:Lung / Q000528:radiation effects*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D008297:Male; D011832:Radiation Injuries / Q000000981:diagnostic imaging*; D011859:Radiography; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*
keywords: Computed tomography; Lung toxicity; Radiation pneumonitis; Radiotherapy