title: Kidney transplant in pediatric patients with severe bladder pathology.
abstract: The aim of the current study was to compare results in pediatric renal transplantation of patients with and without SBP. Between 2001 and 2013, a total of 168 kidney transplants were performed at our center. A retrospective analysis was performed and recipients were divided into two groups: NB and SBP. Incidence of surgical complications after procedure, and graft and patient survival were evaluated. A total of 155 recipients (92%) with complete data were analyzed, and 13 recipients that had had previous bladder surgeries were excluded (11 with VUR surgery and two with previous kidney transplants), of the 155 recipients: 123 (79%) patients had NB, and 32 (21%) patients had SBP, with a median follow-up of 60 (1-137) and 52 (1-144) months, respectively. Among post-transplant complications, UTI (68.8% vs. 23%, p < 0.0001) and symptomatic VUR to the graft (40.6% vs. 7.3%, p < 0.0001) were significantly higher in the SBP group. There was no significant difference in overall graft and patient survival between groups. Renal transplantation is safe in pediatric recipients with SBP; however, urologic complications such as UTI and VUR were significantly higher in this group. Graft and patient survival was similar in SBP and NB groups.
authors.affiliation: Department of Urology, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: María Consuelo
authors.initials: MC
authors.lastname: Sierralta
authors.affiliation: Department of Pediatric Surgery, Section of Pediatric Renal Transplantation, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: Gloria
authors.initials: G
authors.lastname: González
authors.affiliation: Department of Urology, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: Claudio
authors.initials: C
authors.lastname: Nome
authors.affiliation: Department of Urology, Section of Pediatric Renal Transplantation, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: Cesar
authors.initials: C
authors.lastname: Pinilla
authors.affiliation: Department of Urology, Section of Pediatric Renal Transplantation, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: Ramón
authors.initials: R
authors.lastname: Correa
authors.affiliation: Methodologist, Universidad Católica de Temuco, Temuco, Chile.
authors.forename: Juan
authors.initials: J
authors.lastname: Mansilla
authors.affiliation: Department of Urology, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: Jorge
authors.initials: J
authors.lastname: Rodríguez
authors.affiliation: Department of Pediatrics, Section of Pediatric Nephrology, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: Angela
authors.initials: A
authors.lastname: Delucchi
authors.affiliation: Department of Urology, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: Francisco
authors.initials: F
authors.lastname: Ossandón
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D015994:Incidence; D007223:Infant; D016030:Kidney Transplantation / Q000401:mortality*; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D001745:Urinary Bladder Diseases / Q000150:complications*
keywords: graft survival; outcome; pediatric kidney transplantation; urological anomalies