title: Pregnancy Rate after Controlled Ovarian Hyperstimulation and Intrauterine Insemination for the Treatment of Endometriosis following Surgery.
abstract: OBJECTIVE
  To compare pregnancy rate after controlled ovarian hyperstimulation and intrauterine insemination (COH-IUI) with no treatment in patients with endometriosis-associated infertility treated with laparoscopy.
  
  
  METHODS
  A clinical cohort study.
  
  
  METHODS
  University-level tertiary care center.
  
  
  METHODS
  238 women with various stages of endometriosis after laparoscopic treatment.
  
  
  METHODS
  Either COH-IUI or follow-up for 12 months.
  
  
  METHODS
  The primary outcome measures were clinical pregnancy and live birth rate. Predictive factors evaluated were female age, maternal BMI, and duration of infertility.
  
  
  RESULTS
  The pregnancy rate attained after the integrated laparoscopy-COH-IUI approach was 53.4%, while it was significantly lower (38.5%) in the control group. Similarly, a significant difference was observed in live births (48.3% versus 34.2%). Patients with severe endometriosis were less likely to achieve pregnancy (38%) and live birth (35%) than their counterparts with milder forms (57% and 53%).
  
  
  CONCLUSIONS
  In patients with endometriosis-based infertility, surgery followed by COH-IUI is more effective than surgery alone.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of General Medicine, Albert Szent-Györgyi Medical Center, University of Szeged, Szeged 6725, Hungary.
authors.forename: Attila
authors.initials: A
authors.lastname: Keresztúri
authors.affiliation: Reproductive Medicine, Department of Obstetrics and Gynecology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
authors.forename: Zoltan
authors.initials: Z
authors.lastname: Kozinszky
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of General Medicine, Albert Szent-Györgyi Medical Center, University of Szeged, Szeged 6725, Hungary.
authors.forename: József
authors.initials: J
authors.lastname: Daru
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of General Medicine, Albert Szent-Györgyi Medical Center, University of Szeged, Szeged 6725, Hungary.
authors.forename: Norbert
authors.initials: N
authors.lastname: Pásztor
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of General Medicine, Albert Szent-Györgyi Medical Center, University of Szeged, Szeged 6725, Hungary.
authors.forename: János
authors.initials: J
authors.lastname: Sikovanyecz
authors.affiliation: Center for Assisted Reproduction, Kaáli Institute, University of Szeged, Szeged 6723, Hungary.
authors.forename: János
authors.initials: J
authors.lastname: Zádori
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of General Medicine, Albert Szent-Györgyi Medical Center, University of Szeged, Szeged 6725, Hungary.
authors.forename: Virág
authors.initials: V
authors.lastname: Márton
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of General Medicine, Albert Szent-Györgyi Medical Center, University of Szeged, Szeged 6725, Hungary.
authors.forename: Sándor
authors.initials: S
authors.lastname: Koloszár
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of General Medicine, Albert Szent-Györgyi Medical Center, University of Szeged, Szeged 6725, Hungary.
authors.forename: János
authors.initials: J
authors.lastname: Szöllősi
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of General Medicine, Albert Szent-Györgyi Medical Center, University of Szeged, Szeged 6725, Hungary.
authors.forename: Gábor
authors.initials: G
authors.lastname: Németh
mesh_terms: D000328:Adult; D017677:Age Distribution; D015331:Cohort Studies; D003131:Combined Modality Therapy / Q000706:statistics & numerical data; D015897:Comorbidity; D004715:Endometriosis / Q000453:epidemiology* / Q000601:surgery*; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007246:Infertility / Q000453:epidemiology / Q000517:prevention & control*; D007315:Insemination, Artificial / Q000706:statistics & numerical data*; D010535:Laparoscopy / Q000706:statistics & numerical data; D050498:Live Birth / Q000453:epidemiology; D010062:Ovulation Induction / Q000706:statistics & numerical data*; D011247:Pregnancy; D018873:Pregnancy Rate; D015995:Prevalence; D012307:Risk Factors; D016896:Treatment Outcome