title: Prevalence of Chronic Kidney Disease and the Incidence of Acute Kidney Injury in Patients with Coronary Artery Disease in Mumbai, India.
abstract: OBJECTIVE
  To determine the prevalence of chronic kidney disease (CKD) and incidence of acute kidney injury (AKI) in patients with coronary artery disease (CAD) demonstrated on coronary angiography.
  
  
  METHODS
  Totally, 125 patients admitted to Lilavati Hospital and Research Centre, Mumbai, with CAD were included in the study.
  
  
  RESULTS
  Left anterior descending artery was the major vessel involved (40%), followed by a circumflex artery (21.6%). 49 out of 125 (39.2%) were found to have underlying CKD. 69% (34) of these CKD patients developed AKI. 21 out of 34 patients who developed AKI required hemodialysis. Only 47.1% (16 out of 34) of CKD patients had complete recovery, 29% had partial recovery, and 23% had no recovery of their renal function from AKI. Statistically significant number of patients in CKD group had no recovery from AKI as compared to non-CKD group (23.5% vs. 0%).
  
  
  CONCLUSIONS
  Our study concludes that there is a very high prevalence of CKD (39.2%) in patients with CAD and AKI is a very important complication (38.4%) in these patients. Considering such a high prevalence of CKD, nephrology referral must be considered in patients with abnormal urinalysis, spot urinary protein to creatinine ratio and in patients whose creatinine clearance is <60 ml/min.
authors.affiliation: Department of Medicine, Division of Nephrology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Mandya, Karnataka, India.
authors.forename: Pavan
authors.initials: P
authors.lastname: Malleshappa
authors.affiliation: Department of Nephrology, Global Hospital, Mumbai, Maharashtra, India.
authors.forename: Bharat V
authors.initials: BV
authors.lastname: Shah
keywords: Acute kidney injury; chronic kidney disease; coronary artery disease; hemodialysis