title: [Forensic Application of Microperimetry and Visual Evoked Potential in Macular Disease].
abstract: OBJECTIVE
  e To find the correlation between real best corrected visual acuity (BCVA) and testing results of microperimetry and visual evoked potential (VEP) and to explore a new method in recording BCVA in macular disease.
  
  
  METHODS
  Sixty-two patients with macular disease (macular disease group, 62 eyes) and eighteen healthy volunteers (control group, 36 eyes) had BCVA, microperimetry and VEP recorded.
  
  
  RESULTS
  (1) By microperimetry, the values of retinal mean sensitivity and fixation percentage in macular disease group were lower than that in control group. The bicurve ellipse area in macular disease group was higher than that in control group. By VEP, P100 amplitude under 0.5 cpd and 2 cpd in macular disease group were significantly higher than that in control group and the latency was prolonged (P < 0.05). (2) In macular disease group, BCVA had significant positive correlation with retinal mean sensitivity, bicurve ellipse area, macular central 2 degrees and 4 degrees fixation percentage, respectively (P < 0.05). There was a significant correlation between retinal mean sensitivity and P100 amplitude (P < 0.05). (3) Multiple linear regression equation was y = 0.053 x1+0.008 x3+3.897 (y was BCVA, while x1 was retinal mean sensitivity and x3 was P100 amplitude under 2 cpd).
  
  
  CONCLUSIONS
  Combined use of microperimetry and VEP is useful in the assessment of BCVA in macular disease.
authors.forename: Shu
authors.initials: S
authors.lastname: Zhou
authors.forename: Dong-mei
authors.initials: DM
authors.lastname: Liu
authors.forename: Shu-ya
authors.initials: SY
authors.lastname: Peng
authors.forename: Jing
authors.initials: J
authors.lastname: Sun
authors.forename: Rui-jue
authors.initials: RJ
authors.lastname: Liu
authors.forename: Wen-tao
authors.initials: WT
authors.lastname: Xia
mesh_terms: D016022:Case-Control Studies; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005123:Eye; D006801:Humans; D008266:Macula Lutea / Q000503:physiopathology*; D012160:Retina; D012164:Retinal Diseases / Q000473:pathology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests / Q000379:methods*