title: [Autoimmune hemolytic anemia as a paraneoplastic syndrome associated with solid tumors].
abstract: Autoimmune hemolytic anemia (AIHA) is a rare paraneoplastic syndrome (PNS) associated with malignant solid tumors. Patients with PNS-AIHA are often refractory to steroid treatment before surgery. The mechanisms underlying PNS-AIHA are not well understood. In a recent case report describing a patient with PNS-AIHA, the antibodies had formed against the tumor antigens and cross-reacted with the erythrocyte antigen: band 3. Further study of this case may provide clues to finding novel mechanisms and targets for immunotherapy against AIHA and solid tumors.
authors.affiliation: Center for Community Medicine, Jichi Medical University.
authors.forename: Toyomi
authors.initials: T
authors.lastname: Kamesaki
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000209:etiology / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology; D001324:Autoantigens / Q000276:immunology / Q000378:metabolism; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D011485:Protein Binding
chemical_list: D001323:Autoantibodies; D001324:Autoantigens