title: Forensic parameters of the Investigator DIPplex kit (Qiagen) in six Mexican populations.
abstract: Allele frequencies and statistical parameters of forensic efficiency for 30 deletion-insertion polymorphisms (DIPs) were estimated in six Mexican populations. For this purpose, 421 unrelated individuals were analyzed with the Investigator DIPplex kit. The Hardy-Weinberg and linkage equilibrium was demonstrated for this 30-plex system in all six populations. We estimated the combined power of discrimination (PD ≥ 99.999999%) and combined power of exclusion (PE ≥ 98.632705%) for this genetic system. A low but significant genetic structure was demonstrated among these six populations by pairwise comparisons and AMOVA (F ST ≥ 0.7054; p ≤ 0.0007), which allows clustering populations in agreement with geographical criteria: Northwest, Center, and Southeast.
authors.affiliation: Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, Universidad de Guadalajara (CUCiénega-UdeG), Av. Universidad #1115, Col. Paso Blanco, CP 47810, Ocotlán, Jalisco, México.
authors.forename: G
authors.initials: G
authors.lastname: Martínez-Cortés
authors.affiliation: Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, Universidad de Guadalajara (CUCiénega-UdeG), Av. Universidad #1115, Col. Paso Blanco, CP 47810, Ocotlán, Jalisco, México.
authors.forename: M
authors.initials: M
authors.lastname: García-Aceves
authors.affiliation: Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, Universidad de Guadalajara (CUCiénega-UdeG), Av. Universidad #1115, Col. Paso Blanco, CP 47810, Ocotlán, Jalisco, México.
authors.forename: A F
authors.initials: AF
authors.lastname: Favela-Mendoza
authors.affiliation: Instituto de Investigación Biomédica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara (CUCS-UdeG), Guadalajara, Jalisco, México.
authors.forename: J F
authors.initials: JF
authors.lastname: Muñoz-Valle
authors.affiliation: Escuela de Biología, Universidad Autónoma de Sinaloa, Culiacán, Sinaloa, México.
authors.forename: J S
authors.initials: JS
authors.lastname: Velarde-Felix
authors.affiliation: Instituto de Investigación en Genética Molecular, Centro Universitario de la Ciénega, Universidad de Guadalajara (CUCiénega-UdeG), Av. Universidad #1115, Col. Paso Blanco, CP 47810, Ocotlán, Jalisco, México. hrangel13@hotmail.com.
authors.forename: H
authors.identifier: http://orcid.org/0000-0003-2641-8782
authors.initials: H
authors.lastname: Rangel-Villalobos
mesh_terms: D016172:DNA Fingerprinting; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D054643:INDEL Mutation; D015810:Linkage Disequilibrium; D008800:Mexico; D016133:Polymerase Chain Reaction / Q000295:instrumentation*; D011110:Polymorphism, Genetic
keywords: Amerindians; DIPs; Indels; Investigator DIPplex; Mestizos; Mexican populations; Purépechas