title: Potential predictors for health-related quality of life in stroke patients undergoing inpatient rehabilitation.
abstract: BACKGROUND
  Improving HRQOL is the desired outcome for patients with stroke undergoing inpatient rehabilitation services. This study aimed to comprehensively identify the potential health-related quality of life (HRQOL) predictors in patients with stroke undergoing inpatient rehabilitation within the first year after stroke; thus far, such an investigation has not been conducted.
  
  
  METHODS
  We enrolled 119 patients (88 males, 31 females) with stroke, and examined 12 potential predictors: age, sex, stroke type, stroke side, duration after onset, cognition (Mini-Mental State Examination; MMSE), depression (Beck Depression Inventory-II), stroke severity (National Institutes of Health Stroke Scale; NIHSS), upper- and lower-extremity motor function scores of the Fugl-Meyer Assessment (FMA) scale, balance (Berg Balance Scale; BBS), and functional status (Functional Independence Measure). HRQOL was measured using Stroke Impact Scale (SIS) 3.0.
  
  
  RESULTS
  NIHSS score predicted the strength domain and total SIS score (41.5% and 41.7% of the variances, respectively). BBS score was a major predictor of mobility and participation/role domains (48.6% and 10% of the variances, respectively). MMSE score predicted the memory and communication domains (22.5% and 36.3% of the variances, respectively). Upper extremity score of the FMA scale predicted the daily living/instrumental activities of daily life and hand function domains (40.3% and 20.6% of the variances, respectively). Stroke side predicted the emotion domain (11.6% of the variance).
  
  
  CONCLUSIONS
  NIHSS, MMSE, BBS, FMA, and stroke side predicted most HRQOL domains. These findings suggest that different factors predicted various HRQOL domains in patients with stroke.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Chiayi, No.6, Sec. W., Jiapu Rd., Puzih City, Chiayi County, 61363, Taiwan. fateman53@yahoo.com.tw.|School of Medicine, College of Medicine, Chang Gung University, Taoyuan, No.259, Wunhua 1st Rd., Kuei-Shan Dist., Taoyuan City, 33302, Taiwan. fateman53@yahoo.com.tw.
authors.forename: Chien-Min
authors.initials: CM
authors.lastname: Chen
authors.affiliation: Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, No.5, Fushing St. , Kuei-Shan Dist., Taoyuan City, 33305, Taiwan. cgmhcmrp2@gmail.com.|Graduate Institute of Early Intervention, College of Medicine, Chang Gung University, Taoyuan, No.259, Wunhua 1st Rd. , Kuei-Shan Dist., Taoyuan City, 33302, Taiwan. cgmhcmrp2@gmail.com.
authors.forename: Chih-Chien
authors.initials: CC
authors.lastname: Tsai
authors.affiliation: School of Medicine, College of Medicine, Chang Gung University, Taoyuan, No.259, Wunhua 1st Rd., Kuei-Shan Dist., Taoyuan City, 33302, Taiwan. chiaying928@yahoo.com.|Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, No.5, Fushing St. , Kuei-Shan Dist., Taoyuan City, 33305, Taiwan. chiaying928@yahoo.com.
authors.forename: Chia-Ying
authors.initials: CY
authors.lastname: Chung
authors.affiliation: Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, No.5, Fushing St. , Kuei-Shan Dist., Taoyuan City, 33305, Taiwan. clingchen@gmail.com.|Graduate Institute of Early Intervention, College of Medicine, Chang Gung University, Taoyuan, No.259, Wunhua 1st Rd. , Kuei-Shan Dist., Taoyuan City, 33302, Taiwan. clingchen@gmail.com.
authors.forename: Chia-Ling
authors.initials: CL
authors.lastname: Chen
authors.affiliation: School of Medicine, College of Medicine, Chang Gung University, Taoyuan, No.259, Wunhua 1st Rd., Kuei-Shan Dist., Taoyuan City, 33302, Taiwan. dr1110@cgmh.org.tw.|Department of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Linkou, No.5, Fushing St. , Kuei-Shan Dist., Taoyuan City, 33305, Taiwan. dr1110@cgmh.org.tw.
authors.forename: Katie Ph
authors.initials: KP
authors.lastname: Wu
authors.affiliation: Department of Industrial Engineering & Management, National Taipei University of Technology, No.1, Sec. 3, Zhongxiao E. Rd., Daan Dist., Taipei City, 10608, Taiwan. imhcchen@ntut.edu.tw.
authors.forename: Hsieh-Ching
authors.initials: HC
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D003863:Depression / Q000209:etiology; D005260:Female; D006801:Humans; D007297:Inpatients / Q000523:psychology* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications / Q000523:psychology*; D000071939:Stroke Rehabilitation; D017741:Survivors / Q000523:psychology* / Q000706:statistics & numerical data; D014481:United States; D034941:Upper Extremity / Q000503:physiopathology