title: Colorectal cancer liver metastases: laparoscopic and open radiofrequency-assisted surgery.
abstract: BACKGROUND
  The liver is the most common site of colorectal metastases (colorectal liver metastases - CLM). Surgical treatment in combination with oncological therapy is the only potentially curative method. Unfortunately, only 10-25% of patients are suitable for surgery. Traditionally, open liver resection (OLR) is usually performed. However, laparoscopic liver resection (LLR) has become popular worldwide in the last two decades.
  
  
  OBJECTIVE
  To evaluate the effectiveness and benefits of radiofrequency minor LLR of CLM in comparison with OLR.
  
  
  METHODS
  The indication for surgery was CLM and the possibility to perform minor laparoscopic or OLR not exceeding two hepatic segments according to Couinaud's classification.
  
  
  RESULTS
  Sixty-six minor liver resections for CLM were performed. Twenty-five (37.9%) patients underwent a laparoscopic approach and 41 (62.1%) patients underwent OLR. The mean operative time was 166.4 min for LLR and 166.8 min for OLR. Average blood loss was 132.3 ±218.0 ml during LLR and 149.5 ±277.5 ml during OLR. Length of hospital stay was 8.4 ±2.0 days for LLR and 10.5 ±5.8 days for OLR. All resections were R0. There was no case of mortality. Postoperative complications were recognized in 9 (13.6%) patients: 8 in the group of OLR patients and 1 in the LLR group. The median survival time for LLR was 70.5 months and for OLR 61.9 months. The 5-year overall survival rate was higher for LLR vs. OLR - 82.1% vs. 69.8%. The average length of disease-free interval after LLR was greater (52.2 months) in comparison with OLR (49.4%). The 5-year disease-free interval was 63.2% for LLR and 58% for OLR.
  
  
  CONCLUSIONS
  Outcomes and oncological radicality of minor laparoscopic liver resections of CLM are comparable to outcomes of OLR.
authors.affiliation: University Hospital Ostrava, Ostrava, Czech Republic ; VŠB - Techcnical University of Ostrava, Ostrava, Czech Republic ; Imperial College London, London, United Kingdom ; University of Ostrava, Ostrava, Czech Republic.
authors.forename: Petr
authors.initials: P
authors.lastname: Vavra
authors.affiliation: VŠB - Techcnical University of Ostrava, Ostrava, Czech Republic.
authors.forename: Jana
authors.initials: J
authors.lastname: Nowakova
authors.affiliation: University Hospital Ostrava, Ostrava, Czech Republic.
authors.forename: Petr
authors.initials: P
authors.lastname: Ostruszka
authors.affiliation: VŠB - Techcnical University of Ostrava, Ostrava, Czech Republic.
authors.forename: Martin
authors.initials: M
authors.lastname: Hasal
authors.affiliation: University Hospital Ostrava, Ostrava, Czech Republic.
authors.forename: Jana
authors.initials: J
authors.lastname: Jurcikova
authors.affiliation: University Hospital Ostrava, Ostrava, Czech Republic.
authors.forename: Lubomir
authors.initials: L
authors.lastname: Martinek
authors.affiliation: VŠB - Techcnical University of Ostrava, Ostrava, Czech Republic.
authors.forename: Marek
authors.initials: M
authors.lastname: Penhaker
authors.affiliation: University Hospital Ostrava, Ostrava, Czech Republic ; University of Ostrava, Ostrava, Czech Republic.
authors.forename: Peter
authors.initials: P
authors.lastname: Ihnat
authors.affiliation: Imperial College London, London, United Kingdom.
authors.forename: Nagy
authors.initials: N
authors.lastname: Habib
authors.affiliation: University Hospital Ostrava, Ostrava, Czech Republic ; University of Ostrava, Ostrava, Czech Republic.
authors.forename: Pavel
authors.initials: P
authors.lastname: Zonca
keywords: colorectal cancer; laparoscopic liver resection; liver metastases; radiofrequency