title: Postoperative IOL Axial Movements and Refractive Changes After Femtosecond Laser-assisted Cataract Surgery Versus Conventional Phacoemulsification.
abstract: OBJECTIVE
  To evaluate intraocular lens (IOL) axial movements and refractive changes during a 6-month follow-up period after femtosecond laser-assisted cataract surgery and conventional cataract surgery, investigate the influence of capsulorhexis features on postoperative IOL axial changes, and assess the prediction error for both techniques.
  
  
  METHODS
  Eighty eyes of 80 candidates for cataract extraction were randomized into two groups: femtosecond laser (40 eyes) and manual (40 eyes).
  
  
  RESULTS
  The overall anterior chamber depth variation was significantly lower in the femtosecond laser group compared to the manual group during follow-up (P<.001). At 30 and 180 days postoperatively, the mean spherical equivalent showed a hyperopic shift (0.09±0.28 diopters [D]) in the femtosecond laser group and a myopic shift in the manual group (-0.25±0.18 D). Median absolute error was not significantly different between the two groups with standard formulas ranging between 0.29 and 0.64 (Hoffer Q) in the femtosecond laser group and between 0.24 (SRK-T) and 0.55 D (Hoffer Q) in the manual group. There was a significant lower deviation from intended versus achieved capsulotomy/capsulorhexis area in the femtosecond laser group (P<.001) compared to the manual group. The femtosecond laser group showed better IOL centration compared to the manual group at all time periods (P<.001).
  
  
  CONCLUSIONS
  Femtosecond laser-assisted cataract surgery was related to a lower overall variability of anterior chamber depth compared to conventional cataract surgery with more stable postoperative refraction. The two techniques did not show significant differences of prediction error.
authors.forename: Lisa
authors.initials: L
authors.lastname: Toto
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Mastropasqua
authors.forename: Peter A
authors.initials: PA
authors.lastname: Mattei
authors.forename: Luca
authors.initials: L
authors.lastname: Agnifili
authors.forename: Alessandra
authors.initials: A
authors.lastname: Mastropasqua
authors.forename: Gennaro
authors.initials: G
authors.lastname: Falconio
authors.forename: Marta
authors.initials: M
authors.lastname: Di Nicola
authors.forename: Leonardo
authors.initials: L
authors.lastname: Mastropasqua
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology; D060437:Artificial Lens Implant Migration / Q000209:etiology / Q000503:physiopathology*; D002387:Cataract Extraction; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications; D011446:Prospective Studies; D019591:Pseudophakia / Q000503:physiopathology; D012029:Refraction, Ocular / Q000502:physiology; D012030:Refractive Errors / Q000209:etiology / Q000503:physiopathology*; D014792:Visual Acuity / Q000502:physiology