title: Hereditary HaemorrhagicTelangiectasia--A Rare Cause of Severe Anaemia.
abstract: Hereditary Haemorrhagic Telangiectasia also known as Osler-Rendu-Weber disease is a rare autosomal dominant disorder affecting small vessels of skin and mucosa, usually misdiagnosed because of its non specific symptomatology. This disease usually presents as epistaxis, gastrointestinal bleeding and visceral arteriovenous malformations. Although the epistaxis and gastrointestinal blood loss can result in anaemia, patients with hereditary haemorrhagic telangiectasia rarely presents as severe anaemia. Herein, we report a case of a 60 year-old man with severe anaemia resulting in congestive cardiac failure who ultimately was diagnosed as hereditary haemorrhagic telangiectasia with recurrent epistaxis as a cause of his severe anaemia.
authors.forename: Prachee
authors.initials: P
authors.lastname: Deshpande
authors.forename: Shreepad
authors.initials: S
authors.lastname: Bhat
authors.forename: Anup
authors.initials: A
authors.lastname: Karmarkar
mesh_terms: D000740:Anemia / Q000209:etiology*; D004844:Epistaxis / Q000150:complications / Q000209:etiology; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012008:Recurrence; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications* / Q000175:diagnosis / Q000235:genetics