title: General anaesthesia is better suitable than epidural anaesthesia for surgical removal of giant intraperitoneal tumours.
abstract: OBJECTIVE
  Our objective was to compare general and epidural anaesthesia for surgical resection of giant intraperitoneal tumours.
  
  
  METHODS
  80 patients with giant intraperitoneal tumours were randomly divided into two groups which respectively received general or epidural anaesthesia prior to the surgery. General anaesthesia was done under intubation and mechanical ventilation.
  
  
  RESULTS
  Vital signs, including diastolic pressure, systolic pressure, heart rate and oxygen saturation, were not significantly different between two groups before the surgery. Vital signs were decreased in patients of both groups after surgery. However, vital signs in the general anaesthesia group were markedly higher than in the epidural anaesthesia group (p < 0.05), indicating that the changes of vital signs were less pronounced in the general anaesthesia group. Furthermore, the operation time in this group was markedly shorter than in the epidural anaesthesia group, while the success rate was markedly higher. In addition, the intraoperative blood loss and infusion volume were both markedly lower in the general anaesthesia group, as well as the occurrence rate of supine position (p < 0.05 for all comparisons). Occurrence of heart failure, lung edema, altered water-electrolyte balance, ECG abnormalities in patients undergoing surgery under general anaesthesia group was significantly lower (p < 0.05 vs. patients under epidural anaesthesia). There were no deaths in either patient group, and all patients were successfully cured and discharged.
  
  
  CONCLUSIONS
  General anaesthesia under intubation and mechanical ventilation is better suited for surgical removal of giant intraperitoneal tumours.
authors.affiliation: Anaesthesia Department, Zhangjiagang Jinfeng People Hospital, Zhangjiagang, China. ghyxx1234@sohu.com.
authors.forename: H
authors.initials: H
authors.lastname: Gao
authors.forename: H-Y
authors.initials: HY
authors.lastname: Guo
mesh_terms: D000293:Adolescent; D000328:Adult; D000767:Anesthesia, Epidural / Q000379:methods*; D000768:Anesthesia, General / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000601:surgery*; D055815:Young Adult