title: [Prevalence of cytological atypia and high-risk human papillomavirus infection in Panará indigenous women in Central Brazil].
abstract: The aim of this study was to analyze the prevalence of cytological atypia and human papillomavirus infection in Panará indigenous women in 2006-2007. This was a cross-sectional observational study with data obtained from vaginal cervical samples for Pap smear and hybrid capture, colposcopy, and biopsy. The study included 86 females 12 years or older with a history of sexual activity. 10.7% of the women were diagnosed with cytological atypia and 28.6% were infected with high-risk HPV genotypes, which were more common among young women (mean = 25.6 years). Of these, 41.7% were positive for high-risk HPV genotypes 16 and/or 18 and/or 45, and the majority (58.3%) for other high-risk HPV genotypes. The study concludes that this group of indigenous women constitutes a special population, susceptible to develop precursor lesions for cervical cancer and vulnerable to STDs. Preventive measures are required, such as systematic cervical cancer screening and HPV immunization.
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Douglas Antonio
authors.initials: DA
authors.lastname: Rodrigues
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Érica Ribeiro
authors.initials: ÉR
authors.lastname: Pereira
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Lavinia Santos de Souza
authors.initials: LS
authors.lastname: Oliveira
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Neila Maria de Góis
authors.initials: NM
authors.lastname: Speck
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Suely Godoy Agostinho
authors.initials: SG
authors.lastname: Gimeno
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002648:Child; D003430:Cross-Sectional Studies; D055088:Early Detection of Cancer; D005260:Female; D005838:Genotype; D006801:Humans; D007199:Indians, South American / Q000706:statistics & numerical data*; D008875:Middle Aged; D065006:Papanicolaou Test; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology*; D015995:Prevalence; D012307:Risk Factors; D014626:Vaginal Smears; D055815:Young Adult