title: Platelet Transfusions in the Neonatal Intensive Care Unit.
abstract: There is significant world-wide variability in platelet transfusion thresholds used to transfuse thrombocytopenic neonates. A large multicenter randomized controlled trial comparing 2 different platelet transfusion thresholds in neonates is currently ongoing, and should provide data to guide transfusion practice. However, several studies have found that factors other than the degree of thrombocytopenia determine the bleeding risk. Thus, it will be important to develop better tests to assess primary hemostasis and bleeding risk in neonates.
authors.affiliation: Department of Pediatrics, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Sparger
authors.affiliation: Department of Neonatology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, 171 76 Stockholm, Sweden.
authors.forename: Emoke
authors.initials: E
authors.lastname: Deschmann
authors.affiliation: Division of Newborn Medicine, Boston Children's Hospital, Enders Research Building, Room 961, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: Martha.Sola-Visner@childrens.harvard.edu.
authors.forename: Martha
authors.initials: M
authors.lastname: Sola-Visner
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D017713:Platelet Transfusion / Q000379:methods*; D013921:Thrombocytopenia / Q000628:therapy*
keywords: Neonatal intensive care unit; Platelet transfusions; Thrombocytopenia