title: Thinning of Choroidal Thickness in Patients with Rheumatoid Arthritis Unrelated to Disease Activity.
abstract: OBJECTIVE
  To investigate subfoveal and perifoveal choroidal thickness (CT) in patients with rheumatoid arthritis (RA).
  
  
  METHODS
  A study group of 117 patients with RA and a control group of 46 age-matched healthy individuals were enrolled in the study. Subfoveal and perifoveal CTs were measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Perifoveal CT was measured 1,500 µm nasally and 1,500 µm temporally apart from the foveal center. Relationship between the disease activity score 28 (DAS-28) and subfoveal CT was also evaluated.
  
  
  RESULTS
  The mean subfoveal CT values in the study and control groups were 226.90 ± 43.61 μm and 299.74 ± 48.06 μm, respectively, which made for a statistically significant difference (p < 0.001). Likewise, perifoveal CT values were significantly thinner in the study group when compared with control group. DAS-28 wasn't correlated with subfoveal CT in the study group.
  
  
  CONCLUSIONS
  CT was significantly thinner in patients with RA when compared with healthy controls.
authors.affiliation: a Department of Ophthalmology , Ankara Atatürk Education and Research Hospital , Ankara , Turkey .
authors.forename: Necati
authors.initials: N
authors.lastname: Duru
authors.affiliation: a Department of Ophthalmology , Ankara Atatürk Education and Research Hospital , Ankara , Turkey .
authors.forename: Hasan
authors.initials: H
authors.lastname: Altinkaynak
authors.affiliation: b Department of Rheumatology , Ankara Atatürk Education and Research Hospital , Ankara , Turkey .
authors.forename: Şükran
authors.initials: Ş
authors.lastname: Erten
authors.affiliation: a Department of Ophthalmology , Ankara Atatürk Education and Research Hospital , Ankara , Turkey .
authors.forename: Mehmet Erol
authors.initials: ME
authors.lastname: Can
authors.affiliation: c Department of Ophthalmology , Ankara Numune Education and Research Hospital , Ankara , Turkey , and.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Duru
authors.affiliation: d Department of Physical Therapy and Rehabilitation , Ankara Atatürk Education and Research Hospital , Ankara , Turkey.
authors.forename: Fatma Gülçin
authors.initials: FG
authors.lastname: Uğurlu
authors.affiliation: a Department of Ophthalmology , Ankara Atatürk Education and Research Hospital , Ankara , Turkey .
authors.forename: Nurullah
authors.initials: N
authors.lastname: Çağıl
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000175:diagnosis; D001794:Blood Pressure / Q000502:physiology; D002829:Choroid / Q000000981:diagnostic imaging / Q000473:pathology*; D015862:Choroid Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D041623:Tomography, Optical Coherence
keywords: Choroid; enhanced depth imaging optical coherence tomography; optical coherence tomography; perifoveal choroidal thickness; rheumatoid arthritis; subfoveal choroidal thickness