title: Higher spherical equivalent refractive errors is associated with slower axial elongation wearing orthokeratology.
abstract: OBJECTIVE
  To investigate the relationship between axial length (AL) increase and baseline spherical equivalent refractive errors (SER) in myopic children wearing orthokeratology contact lenses (OK).
  
  
  METHODS
  One hundred fifteen Chinese (115 right eyes) children wearing OK were enrolled in this cohort study. Gender, age, baseline SER, corneal power, corneal astigmatism, and AL at baseline and 2 years after wearing OK were collected. Univariate analysis and trend test were used to estimate the relationship between change in AL and baseline SER.
  
  
  RESULTS
  After univariate analysis, a statistically significant relationship was found between change in AL and baseline SER (β=0.061, 95% CI: 0.015-0.111, P=0.015). In the trend test, after adjusting for potential confounders, higher SER was associated with smaller increases in AL (P trend=0.041).
  
  
  CONCLUSIONS
  The SER at baseline was associated with AL growth in myopic children wearing OK. The higher SER was associated with slower AL growth and control the development of myopia.
authors.affiliation: The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Road, Zhengzhou, China.
authors.forename: Ai-Cun
authors.initials: AC
authors.lastname: Fu
authors.affiliation: Key Laboratory of Geriatrics of Health Ministry, Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
authors.forename: Xing-Lin
authors.initials: XL
authors.lastname: Chen
authors.affiliation: The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Road, Zhengzhou, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Lv
authors.affiliation: People's Hospital of Zhengzhou, Zhengzhou, China.
authors.forename: Shu-Lin
authors.initials: SL
authors.lastname: Wang
authors.affiliation: The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Road, Zhengzhou, China.
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Shang
authors.affiliation: The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Road, Zhengzhou, China.
authors.forename: Xiu-Hong
authors.initials: XH
authors.lastname: Li
authors.affiliation: The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Road, Zhengzhou, China. Electronic address: 109848196@qq.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D000293:Adolescent; D001251:Astigmatism / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D058452:Axial Length, Eye; D002648:Child; D003261:Contact Lenses; D019781:Corneal Topography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009216:Myopia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D054158:Orthokeratologic Procedures / Q000379:methods*; D012029:Refraction, Ocular / Q000502:physiology*; D012189:Retrospective Studies
keywords: Axial length; Myopia control; Orthokeratology; Spherical equivalent refractive errors