title: Health after pregnancy in the mother with diabetes.
abstract: Progression of retinopathy and nephropathy in women with diabetes occurs, at least temporarily, during pregnancy and postpartum. However, normotensive pregnancy seems to have no detrimental effects regarding the long-term progression of any microvascular complication. Increased risk from pregnancy induced hypertension without proteinuria and with proteinuria (pre-eclampsia) relates mainly to the association with kidney disease in diabetes, and poor glycemic control. A history of pre-eclampsia or pregnancy induced hypertension is an important prognostic factor for micro- and macro-vascular complications later in life. Data regarding the long-term effects of hypertensive pregnancies on late complications of diabetes suggest that women with diabetes should be monitored regularly and nephroprotective treatment initiated early.
authors.affiliation: Faculty of Medicine, Turku University & Turku University Hospital, Satakunta Central Hospital, Sairaalantie 3, 28500 Pori, Finland.
authors.forename: Risto
authors.initials: R
authors.lastname: Kaaja
authors.affiliation: Abdominal Center Nephrology, Helsinki University Central Hospital, Haartmaninkatu 4, 00290 Helsinki, Finland.|Folkhälsan Institute of Genetics, Folkhälsan Research Center, Biomedicum HelsinkiHaartmaninkatu 8 FI-00290, Helsinki, Finland.|Research Program Units, Diabetes & Obesity, PO Box 63, Haartmaninkatu 8, FI-00014 University of Helsinki, Finland.
authors.forename: Daniel
authors.initials: D
authors.lastname: Gordin
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D016640:Diabetes, Gestational / Q000453:epidemiology; D003928:Diabetic Nephropathies / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000503:physiopathology; D005128:Eye Diseases / Q000453:epidemiology; D005260:Female; D006304:Health Status; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D007674:Kidney Diseases / Q000453:epidemiology; D009035:Mothers; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology / Q000503:physiopathology*; D011254:Pregnancy in Diabetics / Q000503:physiopathology*; D011507:Proteinuria; D016387:Women's Health
keywords: Type 1 diabetes; Type 2 diabetes; gestational diabetes; gestational hypertension; hypertensive disorder; nephropathy; pre-eclampsia; retinopathy