title: Sexual satisfaction and quality of life in survivors of localized cervical and ovarian cancers following fertility-sparing surgery.
abstract: OBJECTIVE
  To determine if sexual satisfaction and sexual quality of life (QOL) are different in survivors of localized cervical and ovarian cancers who undergo fertility-sparing surgery (FSS) as compared with standard surgery.
  
  
  METHODS
  470 survivors of localized cervical and ovarian cancers diagnosed between the ages of 18-40 were recruited from the California Cancer Registry to complete a cross-sectional survey. Validated questionnaires were used to assess sexual satisfaction and sexual QOL.
  
  
  RESULTS
  228 women with localized cervical cancer and 125 with localized ovarian cancer completed the survey. In the cervical cancer group, 92 underwent FSS. Compared with the 84 women who did not undergo FSS (had a hysterectomy, but retained at least one ovary), there was no significant difference in sexual satisfaction or sexual QOL mean scores in women who maintained their uterus (cold-knife cone or trachelectomy), after controlling for age and menopausal status. 82 women with ovarian cancer underwent FSS. Compared with the 39 women that had a bilateral salpingo-oophorectomy, we found no significant differences in sexual satisfaction or sexual QOL in women who maintained at least one ovary (USO or cystectomy), after controlling for age and menopausal status.
  
  
  CONCLUSIONS
  While FSS may allow for post-treatment fertility, it may not confer a significant benefit with regard to sexual satisfaction or sexual QOL. Thus, the decision to perform FSS should not be dictated based on preservation of sexual functioning.
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, 1635 Divisadero, Suite 601, San Francisco, CA 94115, USA; Department of Obstetrics and Gynecology, University of Pennsylvania, 3701 Market Street, Suite 800, Philadelphia, PA 19104, USA. Electronic address: jessica.chan@uphs.upenn.edu.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Chan
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, 1635 Divisadero, Suite 601, San Francisco, CA 94115, USA; Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, 101 Manning Drive Chapel Hill, NC 27514, USA. Electronic address: joe.letourneau@gmail.com.
authors.forename: Joseph
authors.initials: J
authors.lastname: Letourneau
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, 1635 Divisadero, Suite 601, San Francisco, CA 94115, USA. Electronic address: salem.wael@gmail.com.
authors.forename: Wael
authors.initials: W
authors.lastname: Salem
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, 1635 Divisadero, Suite 601, San Francisco, CA 94115, USA; Istanbul Memorial Hospital ART and Reproductive Genetics Center, Piyale Pasa Bulvari, 34385 Okmeydani Sisli, Istanbul, Turkey. Electronic address: aylinpelincil@gmail.com.
authors.forename: Aylin Pelin
authors.initials: AP
authors.lastname: Cil
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, 1635 Divisadero, Suite 601, San Francisco, CA 94115, USA. Electronic address: saiwingchanmd@gmail.com.
authors.forename: Sai-Wing
authors.initials: SW
authors.lastname: Chan
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, 1635 Divisadero, Suite 601, San Francisco, CA 94115, USA. Electronic address: Lee-may.Chen@ucsfmedctr.org.
authors.forename: Lee-May
authors.initials: LM
authors.lastname: Chen
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, 1635 Divisadero, Suite 601, San Francisco, CA 94115, USA. Electronic address: rosenm@obgyn.ucsf.edu.
authors.forename: Mitchell P
authors.initials: MP
authors.lastname: Rosen
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D059247:Fertility Preservation / Q000379:methods / Q000523:psychology; D006801:Humans; D010051:Ovarian Neoplasms / Q000523:psychology* / Q000601:surgery*; D017060:Patient Satisfaction; D011788:Quality of Life; D019529:Sexuality / Q000523:psychology*; D011795:Surveys and Questionnaires; D002583:Uterine Cervical Neoplasms / Q000523:psychology* / Q000601:surgery*
keywords: Cervical cancer; Fertility sparing surgery; Ovarian cancer; Sexual dysfunction; Sexual quality of life; Sexual satisfaction