title: [Colposcopic-histologic eligibility criteria for fertility-sparing surgical management in early-stage cervical cancer].
abstract: BACKGROUND
  The decision whether fertility-sparing surgical management may be successfully applied in women with cervical cancer who wish to preserve their fertility remains a great therapeutic challenge. Such management is possible if no node metastases are expected and the risk of cancer spread beyond the cervix is limited. Thus, precise evaluation of tumor size is necessary.
  
  
  OBJECTIVE
  The aim of the study was to establish cytologic, colposcopic and histologic eligibility criteria for fertility-sparing treatment in women with early-stage cervical cancer.
  
  
  METHODS
  The study included 119 women (aged 25-43 years) diagnosed and operated on due to malignant changes within the cervix. Each subject underwent cytologic and colposcopic examination, followed by histologic evaluation of a large, target section from the most suspicious area of the lesion.
  
  
  RESULTS
  Histologic evaluation revealed stage IA1 in 60 (50.4%), IA2 in 53 (44.5%), and IB1 in 6 (5.1%) patients. Histologic compatibility between target sections and evaluation of the surgical material was 59 (98.4%), 51 (96.2%), and (100%) for stages IA1, IA2, and IB1, respectively
  
  
  CONCLUSIONS
  Proper colposcopic assessment of early-stage invasive cervical cancer (IA) allows to identify the most adequate area for large wedge biopsy That in turn makes it possible to establish proper histologic pre-treatment diagnosis, with an over 95% compatibility with the final histologic evaluation, what conditions fertility-sparing surgical treatment.
authors.forename: Paweł
authors.initials: P
authors.lastname: Basta
authors.forename: Artur
authors.initials: A
authors.lastname: Ludwin
authors.forename: Lukasz
authors.initials: L
authors.lastname: Laskowicz
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Okoń
authors.forename: Janina
authors.initials: J
authors.lastname: Schwarz
mesh_terms: D000328:Adult; D003127:Colposcopy / Q000379:methods; D003581:Cytodiagnosis / Q000379:methods; D004608:Eligibility Determination / Q000706:statistics & numerical data*; D005260:Female; D059247:Fertility Preservation / Q000379:methods*; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D009367:Neoplasm Staging; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*