title: Maternal Mortality in Taiwan: A Nationwide Data Linkage Study.
abstract: BACKGROUND
  To examine the changes in the maternal mortality ratio (MMR) and causes of maternal death in Taiwan based on nationwide linked data sets.
  
  
  METHODS
  We linked four population-based data sets (birth registration, birth notification, National Health Insurance inpatient claims, and cause of death mortality data) to identify maternal deaths for 2004-2011. Subsequently, we calculated the MMR (deaths per 100,000 live births) and the proportion of direct and indirect causes of maternal death by maternal age and year.
  
  
  RESULTS
  Based on the linked data sets, we identified 236 maternal death cases, of which only 102 were reported in officially published mortality data, with an underreporting rate of 57% [(236-102) × 100 / 236]. The age-adjusted MMR was 18.4 in 2004-2005 and decreased to 12.5 in 2008-2009; however, the MMR leveled off at 12.6 in 2010-2011. The MMR increased from 5.2 in 2008-2009 to 7.1 in 2010-2011 for patients aged 15-29 years. Women aged 15-29 years had relatively lower proportion in dying from direct causes (amniotic fluid embolism and obstetric hemorrhage) compared with their counterpart older women.
  
  
  CONCLUSIONS
  Approximately two-thirds of maternal deaths were not reported in officially published mortality data. Routine surveillance of maternal mortality by using enhanced methods is necessary to monitor the health status of reproductive-age women. Furthermore, a comprehensive maternal death review is necessary to explore the preventability of these maternal deaths.
authors.affiliation: Department of Obstetrics and Gynecology, Sin-Lau Christian Hospital, Tainan, Taiwan.
authors.forename: Tung-Pi
authors.initials: TP
authors.lastname: Wu
authors.affiliation: NCKU Research Center for Health Data and Department of Public Health, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Fu-Wen
authors.initials: FW
authors.lastname: Liang
authors.affiliation: Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Huang
authors.affiliation: Department of Statistics, Ministry of Health and Welfare, Taipei, Taiwan.
authors.forename: Lea-Hua
authors.initials: LH
authors.lastname: Chen
authors.affiliation: NCKU Research Center for Health Data and Department of Public Health, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Tsung-Hsueh
authors.initials: TH
authors.lastname: Lu
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D016247:Information Storage and Retrieval; D063130:Maternal Death / Q000706:statistics & numerical data*; D008428:Maternal Mortality; D011247:Pregnancy; D011248:Pregnancy Complications / Q000401:mortality*; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult