title: [Relation between Chinese Medical Constitutions and Chemotherapy-induced Leucopenia in Breast Cancer Patients: a Clinical Study].
abstract: OBJECTIVE
  To analyze the relationship between Chinese medical constitutions and chemotherapy-induced leucopenia (CIL) of primary breast cancer patients.
  
  
  METHODS
  Totally 306 breast cancer patients undergoing adjunctive chemotherapy for the 1st time, and effective 291 breast cancer patients were recruited in this study.Nine Basic Constitutional Scale was used before first chemotherapy. Chinese medical constitutions were classified and quantitatively scored. The highest grading for any item of adverse reactions in each case during the whole chemotherapy course was recorded after chemotherapy. Data were statistically analyzed using SPSS16.0.
  
  
  RESULTS
  There was no significant difference in CIL between different chemotherapy regimens and various Chinese medical constitutions of breast cancer patients (P > 0.05). Yang deficiency constitution is one risk factor for CIL. The higher the score of yang deficiency constitution, the more severe the CIL.
  
  
  CONCLUSIONS
  Yang deficiency constitution was correlated with the degree of CIL. The higher the score of yang deficiency constitution, the greater the risk of III-IV grade CIL in breast cancer patients.
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.forename: Qing-hua
authors.initials: QH
authors.lastname: Chen
authors.forename: Ye
authors.initials: Y
authors.lastname: Sun
authors.forename: Yun
authors.initials: Y
authors.lastname: Cai
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Ping-ping
authors.initials: PP
authors.lastname: Han
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhang
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Feng
authors.initials: F
authors.lastname: Ye
mesh_terms: D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007970:Leukopenia / Q000139:chemically induced*; D008516:Medicine, Chinese Traditional; D016711:Yang Deficiency
chemical_list: D004365:Drugs, Chinese Herbal