title: Primary Xanthoma of the Mandible: Report of a Rare Case.
abstract: Xanthoma is a lesion most commonly seen in soft tissues such as the skin, subcutis, or tendon sheaths. Xanthoma formation is often associated with primary or secondary hyperlipidemia. Primary bone xanthomas are extremely rare benign bone lesions not associated with hyperlipidemia, histopathologically characterized by histiocytes, abundant lipid containing macrophages (foam cells), and multinucleated giant cells. Cholesterol clefts can be found in the medullary bone. Less than ten cases of xanthoma in the mandible have been reported. We present a rare primary intrabony xanthoma in a normolipidemic patient.
authors.affiliation: Division of Oral and Maxillofacial Surgery, Department of Dentistry, Montefiore Medical Center, 111 E. 210th Street, Bronx, NY, 10467-2490, USA.
authors.forename: Dominic
authors.initials: D
authors.lastname: Morel
authors.affiliation: Departments of Dental Medicine and Pathology and Laboratory Medicine, NSLIJ Health System, New Hyde Park, NY, USA.|Departments of Dentistry and Pathology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Kelsch
authors.affiliation: Division of Oral and Maxillofacial Surgery, Department of Dentistry, Montefiore Medical Center, 111 E. 210th Street, Bronx, NY, 10467-2490, USA. pnolan@montefiore.org.|Albert Einstein College of Medicine, Bronx, NY, USA. pnolan@montefiore.org.
authors.forename: Patrick J
authors.identifier: http://orcid.org/0000-0002-9304-6715
authors.initials: PJ
authors.lastname: Nolan
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008336:Mandibular Diseases / Q000473:pathology*; D014973:Xanthomatosis / Q000473:pathology*
keywords: Foamy histiocytes; Intraosseous xanthoma; Mandible; Non-Langerhans histiocytic process; Xanthoma