title: [Experience with the use of the bio-active stent coated with titanium nitric oxide compared with zotarolimus-eluting stent: experience of a unit medical high specialty].
abstract: The use of coronary stents in coronary angioplasty has evolved dramatically in its design, type materials, polymers, and a variety of drugs, the use of coronary stents covered nitric oxide have shown satisfactory results in practice, however compared to the results reported drug-eluting stents, there is little information.
  
  
  OBJECTIVE
  The aim of this study was to compare clinical outcomes of a stainless steel stent Bioactive nitric oxide coated titanium (BAS) and a drug-eluting stent zotarolimus (DES) in daily clinical practice.
  
  
  METHODS
  A retrospective, analytical, descriptive and comparative study aimed at evaluating the safety and efficacy of two devices with different characteristics in our population. The primary endpoints were: death, acute infarction (AMI), and re intervention injury Treated (RLT).
  
  
  RESULTS
  A total of 759 patients were included in the study which was performed angioplasty to a single vessel. Were divided into two arms 382 with DES and 377 patients with BAS, the one year follow up was carried in 95%. After this follow-up period, primary points (cardiovascular death, myocardial infarction, TLR and stent thrombosis) for arm DES vs BAS; 9.5% vs 8.5% P=NS but with shorter periods of dual antiplatelet therapy for arm BAS 6.9±4.1 vs 11.1±2.5 months DES P=.0001. The results were independent of the clinical syndrome of presentation.
  
  
  CONCLUSIONS
  After one year of follow no statistically significant difference in major clinical events, there was a trend in favour of BAS vs SM with respect to revascularization of the target lesion without reaching statistical significance.
authors.affiliation: Departamento Hemodinamia Unidad Medica de Alta Especialidad, No 34, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, México.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Garcia-Gutierrez
authors.affiliation: Direccion del Departamento Hemodinamia Unidad Medica de Alta Especialidad,No 34, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, México. Electronic address: palaciosrj@prodigy.net.mx.
authors.forename: Juan M
authors.initials: JM
authors.lastname: Palacios-Rodríguez
authors.affiliation: Departamento Hemodinamia Unidad Medica de Alta Especialidad, No 34, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, México.
authors.forename: Horacio G
authors.initials: HG
authors.lastname: Cordova-Correa
authors.affiliation: Departamento Hemodinamia Unidad Medica de Alta Especialidad, No 34, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, México.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Becerra-Laguna
authors.affiliation: Departamento Hemodinamia Unidad Medica de Alta Especialidad, No 34, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, México.
authors.forename: Hugo A
authors.initials: HA
authors.lastname: López-López
authors.affiliation: Departamento Hemodinamia Unidad Medica de Alta Especialidad, No 34, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, México.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Salinas Aragón
authors.affiliation: Departamento Hemodinamia Unidad Medica de Alta Especialidad, No 34, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, México.
authors.forename: Jorge
authors.initials: J
authors.lastname: García-Bonilla
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000601:surgery*; D009204:Myocardial Revascularization / Q000379:methods*; D009569:Nitric Oxide / Q000008:administration & dosage*; D011474:Prosthesis Design; D012189:Retrospective Studies; D020123:Sirolimus / Q000008:administration & dosage / Q000031:analogs & derivatives*; D014025:Titanium / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D009569:Nitric Oxide; D014025:Titanium; C489443:zotarolimus; D020123:Sirolimus
keywords: Angioplastia; Angioplasty; Bioactive stenting; Drug eluting stent; México; Stent bioactivo; Stent liberador de fármaco; Stent thrombosis; Trombosis del stent