title: Hyperglycemia-associated Hemichorea-hemiballism: The Spectrum of Clinical Presentation.
abstract: Hyperglycemia rarely manifests as hemichorea-hemiballism (HH), which is characterized by simple partial motor seizures. One of the difficulties in the management of hyperglycemia-induced HH is the failure to recognize this entity due to its relatively uncommon presentation. We herein present a case series of hyperglycemia-associated dyskinesias, highlighting the different possible clinical presentations of this entity. Both hyperglycemia and hyperosmolality are probable predisposing factors, while ketoacidosis has a protective role in preventing the dyskinesias. One of our patients had ketotic hyperglycemia leading to HH, a previously unreported finding. Early recognition of this entity is crucial as prompt glycemic control leads to the resolution of symptoms and signs.
authors.affiliation: Department of Endocrinology, Singapore General Hospital, Singapore.
authors.forename: Pc
authors.initials: P
authors.lastname: Lee
authors.forename: Pc
authors.initials: P
authors.lastname: Kek
authors.forename: Awe
authors.initials: A
authors.lastname: Soh
mesh_terms: D000368:Aged; D001786:Blood Glucose; D002819:Chorea / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D020820:Dyskinesias / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin