title: Oxidative inactivation of NiFeSe hydrogenase.
abstract: We propose a resolution to the paradox that spectroscopic studies of NiFeSe hydrogenase have not revealed any major signal attributable to Ni(III) states formed upon reaction with O2, despite the fact that two inactive states are formed upon either aerobic or anaerobic oxidation.
authors.affiliation: CNRS, Aix-Marseille Univ., BIP UMR 7281, IMM FR 3479, 31 Chemin J. Aiguier, 13402 Marseille Cedex 20, France. christophe.leger@imm.cnrs.fr.
authors.forename: Pierre
authors.initials: P
authors.lastname: Ceccaldi
authors.forename: Marta C
authors.initials: MC
authors.lastname: Marques
authors.forename: Vincent
authors.initials: V
authors.lastname: Fourmond
authors.forename: Inês Cardoso
authors.initials: IC
authors.lastname: Pereira
authors.forename: Christophe
authors.initials: C
authors.lastname: Léger
mesh_terms: D004789:Enzyme Activation; D006864:Hydrogenase / Q000378:metabolism*; D009532:Nickel / Q000737:chemistry / Q000378:metabolism; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry / Q000378:metabolism
chemical_list: D009532:Nickel; C058560:nickel-iron-selenium hydrogenase; D006864:Hydrogenase; D010100:Oxygen