title: Changes in Kidney Functions during Middle-distance Triathlon in Male Athletes.
abstract: Strenuous exercise induces proteinuria which is related to the intensity of exercise. However, renal responses to each type of exercise during a middle-distance triathlon have not been reported. The present study, carried out on 7 healthy athletes, investigated renal function at rest and after each exercise of a half-triathlon race. Blood and urine samples were collected at rest and after each specific event. Protein excretion and renal clearances were determined on each sample. Compared with resting values, albuminuria was increased by a factor of 30 (p<0.05) after swimming but did not differ from the resting value after cycling and running (p>0.05). Rates of β2-microglobulin and retinol-binding protein excretion did not change throughout the triathlon (p>0.05). Glomerular filtration rate (expressed as creatinine clearance) remained stable after each exercise event, whereas tubular reabsorption rate (expressed as urea clearance) was reduced by 50, 40 and 65% after swimming, cycling and running, respectively, compared to pre-exercise values (p<0.05). Glomerular membrane permeability (expressed as albumin clearance) was significantly increased by the swimming event (13 times, p<0.05). These results suggest that middle-distance triathlon has a noticeable impact on the glomerular membrane permeability (albumin clearance) and elimination of protein waste (urea clearance) depending on exercise type.
authors.affiliation: Faculty of Motor Sciences, Université libre de Bruxelles.
authors.forename: J R
authors.initials: JR
authors.lastname: Poortmans
authors.affiliation: Faculty of Motor Sciences, Université libre de Bruxelles.
authors.forename: F
authors.initials: F
authors.lastname: Jeannaud
authors.affiliation: Faculty of Motor Sciences, Université libre de Bruxelles.
authors.forename: S
authors.initials: S
authors.lastname: Baudry
authors.affiliation: Faculty of Motor Sciences, Université libre de Bruxelles.
authors.forename: A
authors.initials: A
authors.lastname: Carpentier
mesh_terms: D000328:Adult; D000419:Albuminuria; D001642:Bicycling / Q000502:physiology*; D015415:Biomarkers / Q000097:blood / Q000652:urine; D003404:Creatinine / Q000378:metabolism; D005919:Glomerular Filtration Rate; D006400:Hematocrit; D006801:Humans; D007668:Kidney / Q000502:physiology*; D019344:Lactic Acid / Q000097:blood; D008297:Male; D054840:Retinol-Binding Proteins, Cellular / Q000378:metabolism; D012420:Running / Q000502:physiology*; D012709:Serum Albumin / Q000378:metabolism; D013550:Swimming / Q000502:physiology*; D014508:Urea / Q000378:metabolism; D055815:Young Adult; D001613:beta 2-Microglobulin / Q000378:metabolism
chemical_list: D015415:Biomarkers; D054840:Retinol-Binding Proteins, Cellular; D012709:Serum Albumin; D001613:beta 2-Microglobulin; D019344:Lactic Acid; D014508:Urea; D003404:Creatinine