title: Development of predicted no effect concentration (PNEC) for TCS to terrestrial species.
abstract: Triclosan (TCS) is an important broad-spectrum antimicrobial agent widely utilized in a range of personal care products, and is therefore commonly found in the environment. A few studies have been conducted to investigate predicted no effect concentration (PNEC) for TCS on terrestrial organisms. This could be due to lack of toxicity data especially chronic toxicity data for species on various taxonomic levels. In the present study, chronic toxicity of TCS on 6 terrestrial species (3 dicotyledonous plants, 2 monocotyledonous plants and 1 terrestrial invertebrate) were tested. PNEC values of TCS based on toxicity data of 14 terrestrial species (5 dicotyledonous plants, 4 monocotyledonous plants and 5 terrestrial invertebrates) from 4 Phyla and 11 Families were calculated using the log-logistic species sensitivity distribution (SSD) method. The result of our toxicity tests showed that the dicotyledonous plant Lactuca sativa was the most sensitive species to TCS exposure. The PNEC value for TCS was derived to be 0.04-0.21mgkg(-1) when using the log-logistic SSD method. The use of toxicity data from various taxonomic levels is recommended in deriving the PNEC value in the terrestrial environment.
authors.affiliation: State Key Laboratory of Environmental Criteria and Risk Assessment, State Environmental Protection Key Laboratory of Ecological Effect and Risk Assessment of Chemicals, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.
authors.forename: Xiaonan
authors.initials: X
authors.lastname: Wang
authors.affiliation: China Offshore Environmental Services Co. Ltd., Tianjin 300452, China.
authors.forename: Cong
authors.initials: C
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Environmental Criteria and Risk Assessment, State Environmental Protection Key Laboratory of Ecological Effect and Risk Assessment of Chemicals, Chinese Research Academy of Environmental Sciences, Beijing 100012, China. Electronic address: liuzt@craes.org.cn.
authors.forename: Zhengtao
authors.initials: Z
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Environmental Criteria and Risk Assessment, State Environmental Protection Key Laboratory of Ecological Effect and Risk Assessment of Chemicals, Chinese Research Academy of Environmental Sciences, Beijing 100012, China. Electronic address: wangxn@craes.org.cn.
authors.forename: Wanhua
authors.initials: W
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Environmental Criteria and Risk Assessment, State Environmental Protection Key Laboratory of Ecological Effect and Risk Assessment of Chemicals, Chinese Research Academy of Environmental Sciences, Beijing 100012, China.
authors.forename: Lihong
authors.initials: L
authors.lastname: Chen
mesh_terms: D000818:Animals; D054750:Ecotoxicology / Q000379:methods*; D004785:Environmental Pollutants / Q000633:toxicity*; D009835:Oligochaeta / Q000187:drug effects*; D010944:Plants / Q000187:drug effects*; D018570:Risk Assessment; D018675:Toxicity Tests; D014260:Triclosan / Q000633:toxicity*
chemical_list: D004785:Environmental Pollutants; D014260:Triclosan
keywords: Plant; Predicted no effect concentration; Species sensitivity distribution; TCS; Terrestrial invertebrate