title: Pulp tissue response to Portland cement associated with different radio pacifying agents on pulpotomy of human primary molars.
abstract: The objective of this research was to evaluate the response of Portland cement associated with different radio pacifying agents on pulp treatment of human primary teeth by clinical and radiographic exams and microscopic analysis. Thirty mandibular primary molars were randomly divided into the following groups: Group I - Portland cement; Group II - Portland cement with iodoform (Portland cement + CHI3 ); Group III - Portland cement with zirconium oxide (Portland cement + ZrO2 ); and treated by pulpotomy technique (removal of a portion of the pulp aiming to maintain the vitally of the remaining radicular pulp tissue using a therapeutic dressing). Clinical and radiographic evaluations were recorded at 6, 12 and 24 months follow-up. The teeth at the regular exfoliation period were extracted and processed for histological analysis. Data were tested using statistical analysis with a significance level of 5%. The microscopic findings were descriptively analysed. All treated teeth were clinically and radiographically successful at follow-up appointments. The microscopic analysis revealed positive response to pulp repair with hard tissue barrier formation and pulp calcification in the remaining roots of all available teeth. The findings of this study suggest that primary teeth pulp tissue exhibited satisfactory biological response to Portland cement associated with radio pacifying agents. However, further studies with long-term follow-up are needed to determine the safe clinical indication of this alternative material for pulp therapy of primary teeth.
authors.affiliation: Department of Paediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, São Paulo - SP, Brazil.
authors.forename: N
authors.initials: N
authors.lastname: Marques
authors.affiliation: Department of Paediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, São Paulo - SP, Brazil.
authors.forename: N
authors.initials: N
authors.lastname: Lourenço Neto
authors.affiliation: Department of Paediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, São Paulo - SP, Brazil.
authors.forename: A P
authors.initials: AP
authors.lastname: Fernandes
authors.affiliation: Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, São Paulo - SP, Brazil.
authors.forename: C
authors.initials: C
authors.lastname: Rodini
authors.affiliation: Department of Operative Dentistry, Dental Materials and Endodontics, Dental School of Bauru, University of São Paulo, São Paulo - SP, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Hungaro Duarte
authors.affiliation: Department of Paediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, São Paulo - SP, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Rios
authors.affiliation: Department of Paediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, São Paulo - SP, Brazil.
authors.forename: M A
authors.initials: MA
authors.lastname: Machado
authors.affiliation: Department of Paediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, São Paulo - SP, Brazil.
authors.forename: T
authors.initials: T
authors.lastname: Oliveira
mesh_terms: D003738:Dental Cements / Q000378:metabolism*; D003782:Dental Pulp / Q000187:drug effects*; D006651:Histocytochemistry; D006801:Humans; D008963:Molar / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D011672:Pulpotomy / Q000379:methods*; D011859:Radiography
chemical_list: D003738:Dental Cements
keywords: Iodoformium; Portland cement; pulpotomy; tooth deciduous; zirconium