title: EEG and functional ultrasound imaging in mobile rats.
abstract: We developed an integrated experimental framework that extends the brain exploration capabilities of functional ultrasound imaging to awake and mobile rats. In addition to acquiring hemodynamic data, this method further allows parallel access to electroencephalography (EEG) recordings of neuronal activity. We illustrate this approach with two proofs of concept: a behavioral study on theta rhythm activation in a maze running task and a disease-related study on spontaneous epileptic seizures.
authors.affiliation: Institut de Biologie Paris-Seine, INSERM U1130, CNRS UMR 8246, University Pierre et Marie Curie UMCR18, Paris, France.|Institut des Neurosciences Translationnelles de Paris, Paris, France.
authors.forename: Lim-Anna
authors.initials: LA
authors.lastname: Sieu
authors.affiliation: Institut de Biologie Paris-Seine, INSERM U1130, CNRS UMR 8246, University Pierre et Marie Curie UMCR18, Paris, France.|Ecole Doctorale Frontières du Vivant (FdV), Programme Bettencourt, Universite´ Paris Diderot, Sorbonne Paris Cite´, Paris, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Bergel
authors.affiliation: Institut Langevin, Ecole Supérieure de Physique et de Chimie Industrielles de la ville de Paris ParisTech, Paris Sciences et Lettres Research University, CNRS UMR 7587, INSERM U979, Paris, France.
authors.forename: Elodie
authors.initials: E
authors.lastname: Tiran
authors.affiliation: Institut Langevin, Ecole Supérieure de Physique et de Chimie Industrielles de la ville de Paris ParisTech, Paris Sciences et Lettres Research University, CNRS UMR 7587, INSERM U979, Paris, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Deffieux
authors.affiliation: Institut Langevin, Ecole Supérieure de Physique et de Chimie Industrielles de la ville de Paris ParisTech, Paris Sciences et Lettres Research University, CNRS UMR 7587, INSERM U979, Paris, France.
authors.forename: Mathieu
authors.identifier: http://orcid.org/0000-0001-6713-4642
authors.initials: M
authors.lastname: Pernot
authors.affiliation: Institut Langevin, Ecole Supérieure de Physique et de Chimie Industrielles de la ville de Paris ParisTech, Paris Sciences et Lettres Research University, CNRS UMR 7587, INSERM U979, Paris, France.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Gennisson
authors.affiliation: Institut Langevin, Ecole Supérieure de Physique et de Chimie Industrielles de la ville de Paris ParisTech, Paris Sciences et Lettres Research University, CNRS UMR 7587, INSERM U979, Paris, France.
authors.forename: Mickaël
authors.initials: M
authors.lastname: Tanter
authors.affiliation: Institut de Biologie Paris-Seine, INSERM U1130, CNRS UMR 8246, University Pierre et Marie Curie UMCR18, Paris, France.
authors.forename: Ivan
authors.initials: I
authors.lastname: Cohen
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000295:instrumentation*; D004453:Echoencephalography / Q000295:instrumentation*; D004569:Electroencephalography / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008297:Male; D018782:Maze Learning / Q000502:physiology; D018670:Monitoring, Ambulatory / Q000295:instrumentation*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013826:Theta Rhythm / Q000502:physiology*