title: Diffuse 18F-FDG Muscle Uptake in Trichinella spiralis Infection.
abstract: Two patients were referred to our emergency department with myalgia, fever, general malaise, eosinophilia, and elevated serum levels of creatine kinase and troponin T. 18F-FDG PET/CT scan was performed showing a diffuse and homogenous moderately elevated glucose uptake in all muscle groups. Trichinella spiralis infection was confirmed by a muscle biopsy and detection of trichinella antibodies. The muscle biopsy was taken in the left quadriceps because of equal involvement of the skeletal muscles. The differential diagnosis of diffuse 18F-FDG muscle uptake should include trichinella infection, in particular, in the presence of infectious symptoms, eosinophilia, and biochemical signs of muscle damage.
authors.affiliation: From the Departments of *Nuclear Medicine, †Pathology, and ‡Internal Medicine, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Christophe M
authors.initials: CM
authors.lastname: Deroose
authors.forename: Donatienne
authors.initials: D
authors.lastname: Van Weehaeghe
authors.forename: Thomas
authors.initials: T
authors.lastname: Tousseyn
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Van Rompuy
authors.forename: Steven
authors.initials: S
authors.lastname: Vanderschueren
authors.forename: Daniel
authors.initials: D
authors.lastname: Blockmans
authors.forename: Olivier
authors.initials: O
authors.lastname: Gheysens
mesh_terms: D000818:Animals; D001692:Biological Transport; D004058:Diffusion; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000378:metabolism*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D017160:Trichinella spiralis / Q000502:physiology*; D014235:Trichinellosis / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology
chemical_list: D019788:Fluorodeoxyglucose F18