title: Immunologic and Hematological Abnormalities in Necrotizing Enterocolitis.
abstract: Necrotizing enterocolitis (NEC) is a leading cause of mortality in preterm infants. This article reviews the immunologic and hematological abnormalities typically seen in infants with NEC, such as elevated plasma cytokine levels, thrombocytopenia, increased or decreased neutrophil counts, low monocyte counts, and anemia. Some of these findings may provide important diagnostic and prognostic information.
authors.affiliation: Department of Pediatrics, Morsani College of Medicine, Tampa, FL 33606, USA; Department of Molecular Medicine, Morsani College of Medicine, Tampa, FL 33612, USA; Department of Community and Family Health, College of Public Health, University of South Florida, Tampa, FL 33612, USA. Electronic address: akhilm@health.usf.edu.
authors.forename: Akhil
authors.initials: A
authors.lastname: Maheshwari
mesh_terms: D020345:Enterocolitis, Necrotizing / Q000097:blood / Q000150:complications / Q000276:immunology; D006402:Hematologic Diseases / Q000097:blood / Q000209:etiology / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D007231:Infant, Newborn
keywords: Blood counts; Inflammation; Macrophages; Monocytes; NEC; Neutrophils; Platelets; Signaling