title: Rhabdomyosarcoma of the orbit in a four months old infant in Zimbabwe: A case report.
abstract: Infants younger than one year of age with Rhabdomyosarcoma appear to have worse prognosis compared to older children due partly to high rates of local failure. We report a 4 months old infant with orbital rhabdomyosarcoma with poor outcome. Reluctance to use aggressive local control measures and suboptimal chemotherapy dosing are significant contributory factors. Call is made for need for more studies to determine appropriate local therapy in infants with rhabdomyosarcoma.
authors.affiliation: Department of Paediatrics and Child Health, University of Zimbabwe, College of Health Sciences, P.O. Box A 178, Avondale, Harare, Zimbabwe.
authors.forename: I
authors.initials: I
authors.lastname: Chitsike
authors.forename: R
authors.initials: R
authors.lastname: Masanganise
authors.forename: D
authors.initials: D
authors.lastname: Sibanda
authors.forename: P
authors.initials: P
authors.lastname: Kuona
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D003609:Dactinomycin / Q000008:administration & dosage*; D018450:Disease Progression; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage*; D007223:Infant; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology; D009918:Orbital Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D010166:Palliative Care / Q000379:methods; D011379:Prognosis; D018232:Rhabdomyosarcoma, Alveolar / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage*
chemical_list: D000970:Antineoplastic Agents; D003609:Dactinomycin; D014750:Vincristine; D007069:Ifosfamide