title: Is Thrombin Time useful for the assessment of dabigatran concentrations? An in vitro and ex vivo study.
authors.affiliation: Department of Anesthesiology, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium; Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium.
authors.forename: Sarah
authors.initials: S
authors.lastname: Lessire
authors.affiliation: Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Douxfils
authors.affiliation: Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium.
authors.forename: Justine
authors.initials: J
authors.lastname: Baudar
authors.affiliation: Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Bailly
authors.affiliation: Department of Anesthesiology, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium.
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Dincq
authors.affiliation: Department of Anesthesiology, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium.
authors.forename: Maximilien
authors.initials: M
authors.lastname: Gourdin
authors.affiliation: Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Dogné
authors.affiliation: Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium.
authors.forename: Bernard
authors.initials: B
authors.lastname: Chatelain
authors.affiliation: Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium; Hematology Laboratory, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for Life Sciences (NARILIS), CHU Dinant Godinne UcL Namur, Belgium. Electronic address: mullierfrancois@gmail.com.
authors.forename: François
authors.initials: F
authors.lastname: Mullier
mesh_terms: D000991:Antithrombins / Q000008:administration & dosage / Q000097:blood; D001777:Blood Coagulation / Q000187:drug effects; D000069604:Dabigatran / Q000008:administration & dosage* / Q000097:blood*; D016903:Drug Monitoring / Q000379:methods*; D006801:Humans; D066298:In Vitro Techniques; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013918:Thrombin Time / Q000379:methods*; D013927:Thrombosis / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D000991:Antithrombins; D000069604:Dabigatran
keywords: Dabigatran; Dabigatran etexilate; Preoperative period; Thrombin time; Validation studies