title: Modification of the bacterial adhesion of Staphylococcus aureus by antioxidant blooming on polyurethane films.
abstract: Medical device-related infections are a major problem in hospital. The risk of developing an infection is linked to the bacterial adhesion ability of pathogen strains on the device and their ability to form a biofilm. Here we focused on polymer surfaces exhibiting a blooming of antioxidant (Irganox 3114® and Irganox 1076®) on their surface. We tried to put into evidence the effect of such a phenomenon on the bacterial adhesion in terms of number of viable cultivable bacteria and bacteria localization on the surface. We showed that the blooming has a tendency to increase the Staphylococcus aureus adhesion phenomenon in part for topographic reasons.
authors.affiliation: IFR 141, EA 401, UFR de Pharmacie, Université Paris Sud, 92290 Chatenay Malabry, France. Electronic address: johanna.saunier@u-psud.fr.
authors.forename: Johanna
authors.initials: J
authors.lastname: Saunier
authors.affiliation: INRA AgroParisTech, UMR 1319 MICALIS, équipe B2HM, 91300 Massy, France; AgroParisTech INRA, Institut MICALIS, équipe B2HM 91300 Massy, France. Electronic address: jean-marie.herry@jouy.inra.fr.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Herry
authors.affiliation: ISMO, UMR CNRS 8214, Université Paris Sud, 91405 Orsay Cedex, France. Electronic address: Christian.marliere@u-psud.fr.
authors.forename: Christian
authors.initials: C
authors.lastname: Marlière
authors.affiliation: INRA AgroParisTech, UMR 1319 MICALIS, équipe B2HM, 91300 Massy, France; AgroParisTech INRA, Institut MICALIS, équipe B2HM 91300 Massy, France. Electronic address: margareth.renault@jouy.inra.fr.
authors.forename: Margareth
authors.initials: M
authors.lastname: Renault
authors.affiliation: AgroParisTech INRA, Institut MICALIS, équipe B2HM 91300 Massy, France; INRA AgroParisTech, UMR 1319 MICALIS, équipe B2HM, 91300 Massy, France. Electronic address: marie-noelle.bellon-fontaine@agroparistech.fr.
authors.forename: Marie-Noëlle
authors.initials: MN
authors.lastname: Bellon-Fontaine
authors.affiliation: IFR 141, EA 401, UFR de Pharmacie, Université Paris Sud, 92290 Chatenay Malabry, France. Electronic address: najet.yagoubi@u-psud.fr.
authors.forename: Najet
authors.initials: N
authors.lastname: Yagoubi
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D001422:Bacterial Adhesion; D018441:Biofilms / Q000254:growth & development*; D002084:Butylated Hydroxytoluene / Q000031:analogs & derivatives / Q000737:chemistry; D008567:Membranes, Artificial; D011140:Polyurethanes / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000502:physiology*
chemical_list: D000975:Antioxidants; C547465:Irganox 3114; D008567:Membranes, Artificial; D011140:Polyurethanes; D002084:Butylated Hydroxytoluene; C024538:Irganox 1076
keywords: AFM; Antioxidant; Bacterial adhesion; Blooming; Polyurethane; Staphylococcus aureus