title: Diketopyrrolopyrrole-Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging.
abstract: Diketopyrrolopyrrole-based semiconducting polymer nanoparticles with high photostability and strong photoacoustic brightness are designed and synthesized, which results in 5.3-fold photoacoustic signal enhancement in tumor xenografts after systemic administration.
authors.affiliation: Molecular Imaging Program at Stanford Department of Radiology, School of Medicine, Stanford University, CA, 94305, USA.
authors.forename: Kanyi
authors.initials: K
authors.lastname: Pu
authors.affiliation: Department of Chemical Engineering, Stanford University, Stanford, CA, 94305, USA.|Department of Chemistry, Purdue University, West Lafayette, IN, 47907, USA.
authors.forename: Jianguo
authors.initials: J
authors.lastname: Mei
authors.affiliation: Molecular Imaging Program at Stanford Department of Radiology, School of Medicine, Stanford University, CA, 94305, USA.
authors.forename: Jesse V
authors.initials: JV
authors.lastname: Jokerst
authors.affiliation: Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
authors.forename: Guosong
authors.initials: G
authors.lastname: Hong
authors.affiliation: Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
authors.forename: Alexander L
authors.initials: AL
authors.lastname: Antaris
authors.affiliation: Molecular Imaging Program at Stanford Department of Radiology, School of Medicine, Stanford University, CA, 94305, USA.
authors.forename: Niladri
authors.initials: N
authors.lastname: Chattopadhyay
authors.affiliation: Molecular Imaging Program at Stanford Department of Radiology, School of Medicine, Stanford University, CA, 94305, USA.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Shuhendler
authors.affiliation: Department of Chemical Engineering, Stanford University, Stanford, CA, 94305, USA.
authors.forename: Tadanori
authors.initials: T
authors.lastname: Kurosawa
authors.affiliation: Department of Chemical Engineering, Stanford University, Stanford, CA, 94305, USA.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Molecular Imaging Program at Stanford Department of Radiology, School of Medicine, Stanford University, CA, 94305, USA.|Department of Bioengineering, Stanford, CA, 94305, USA.
authors.forename: Sanjiv S
authors.initials: SS
authors.lastname: Gambhir
authors.affiliation: Department of Chemical Engineering, Stanford University, Stanford, CA, 94305, USA.
authors.forename: Zhenan
authors.initials: Z
authors.lastname: Bao
authors.affiliation: Molecular Imaging Program at Stanford Department of Radiology, School of Medicine, Stanford University, CA, 94305, USA.
authors.forename: Jianghong
authors.initials: J
authors.lastname: Rao
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic; D006367:HeLa Cells; D006801:Humans; D007659:Ketones / Q000737:chemistry*; D051379:Mice; D008958:Models, Molecular; D008968:Molecular Conformation; D053758:Nanoparticles / Q000737:chemistry*; D061088:Photoacoustic Techniques / Q000379:methods*; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D012666:Semiconductors
chemical_list: D007659:Ketones; D011108:Polymers; D011758:Pyrroles; C000604894:diketopyrrolopyrrole dye
keywords: contrast agent; photoacoustic imaging; photothermal imaging; semiconducting polymer nanoparticles; tumor imaging