title: Development of a low grade lymphoma in the mastoid bone in a patient with atypical Cogan's syndrome: A case report.
abstract: Cogan's syndrome is a rare disorder characterized by ocular and audiovestibular manifestations in its typical form and caries a wide variety of atypical manifestations. It is considered as an autoimmune disease. We present the first case in the literature of a 67 year old woman with the development of low grade non-Hodgkin lymphoma (NHL) in the mastoid bone in a pre-existing history of atypical Cogan's syndrome. The anatomical development of NHL was to a "target" organ of Cogan's syndrome, which is the inner ear.
authors.affiliation: Department of Opthalmology, Ioannina University Hospital, S. Niarchos Avenue, Ioannina 45500, Greece.
authors.forename: Chris
authors.initials: C
authors.lastname: Kalogeropoulos
authors.affiliation: Department of Medical Oncology, Ioannina University Hospital, S. Niarchos Avenue, Ioannina 45500, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Karachalios
authors.affiliation: Department of Medical Oncology, Ioannina University Hospital, S. Niarchos Avenue, Ioannina 45500, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Pentheroudakis
authors.affiliation: Department of Pathology, Red Cross General Hospital, Athanasaki 1 & Red Cross Str, Athens 11526, Greece.
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Tsikou-Papafrangou
authors.affiliation: Department of Pathology, Red Cross General Hospital, Athanasaki 1 & Red Cross Str, Athens 11526, Greece.
authors.forename: Lydia
authors.initials: L
authors.lastname: Abou-Asabeh
authors.affiliation: Department of Radiology, Ioannina University Hospital, S. Niarchos Avenue, Ioannina 45500, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Argyropoulou
authors.affiliation: Department of Rheumatology, Ioannina University Hospital, S. Niarchos Avenue, Ioannina 45500, Greece.
authors.forename: Alexandros
authors.initials: A
authors.lastname: Drosos
authors.affiliation: Department of Medical Oncology, Ioannina University Hospital, S. Niarchos Avenue, Ioannina 45500, Greece.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Pavlidis
keywords: Cogan’s syndrome; Lymphoma; Mastoid bone; Treatment