title: Adequacy of published screening criteria for retinopathy of prematurity.
abstract: BACKGROUND
  Criteria for screening preterm infants for retinopathy of prematurity vary around the world. We aimed to analyse the efficacy of alternative screening criteria.
  
  
  METHODS
  We collected retrospective data at a tertiary level neonatal nursery.
  
  
  METHODS
  Our participants were 1007 babies, born between 1997 and 2011, at <32 weeks gestational age or <1500 g birth weight (as recommended by the National Health and Medical Research Council in 1996), who had completed follow-up to full retinal vascularization, with defined presence or absence of retinopathy of prematurity.
  
  
  METHODS
  We determined whether disease would be detected using an alternative Australian screening model (gestational age <30 weeks or birth weight <1250 g) or screening criteria utilized in developed countries with similar standards of neonatal care.
  
  
  METHODS
  Detection of retinopathy of prematurity is our main outcome.
  
  
  RESULTS
  Using several of the alternative criteria, two neonates with clinically significant retinopathy of prematurity, one of whom required laser treatment to preserve sight, would not have been screened, and their disease may have gone undetected. Use of <30 weeks gestational age or <1500 g birth weight as the criteria would still have screened these infants but would have reduced the number of infants screened by 24.9%.
  
  
  CONCLUSIONS
  Some commonly utilized international screening criteria for retinopathy of prematurity may risk clinically significant cases being missed and others may screen babies unnecessarily. Alternative criteria should be considered and '<30 weeks gestational age and/or <1500 g birth weight' appears a viable option.
authors.affiliation: Departments of Ophthalmology, Flinders Medical Centre, South Australia, Australia.
authors.forename: Deepa A
authors.initials: DA
authors.lastname: Taranath
authors.affiliation: Department of Ophthalmology, Flinders University, South Australia, Australia.
authors.forename: Dickson D-S
authors.initials: DD
authors.lastname: Oh
authors.affiliation: Department of Ophthalmology, Flinders University, South Australia, Australia.
authors.forename: Miriam C
authors.initials: MC
authors.lastname: Keane
authors.affiliation: Department of Neonatal Perinatal Medicine, Flinders Medical Centre, South Australia, Australia.
authors.forename: Helen
authors.initials: H
authors.lastname: Fabel
authors.affiliation: Department of Neonatal Perinatal Medicine, Flinders Medical Centre, South Australia, Australia.
authors.forename: Peter
authors.initials: P
authors.lastname: Marshall
mesh_terms: D001315:Australia / Q000453:epidemiology; D003941:Diagnostic Techniques, Ophthalmological / Q000592:standards*; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D008403:Mass Screening / Q000592:standards*; D009313:National Health Programs / Q000592:standards; D015997:Neonatal Screening / Q000592:standards*; D017410:Practice Guidelines as Topic / Q000592:standards; D015995:Prevalence; D012178:Retinopathy of Prematurity / Q000175:diagnosis* / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors
keywords: baby; birth weight; gestational age; retinopathy of prematurity; screening