title: [Short history of laboratory diagnostics of allergy in Hungary, current possibilities and future perspectives].
abstract: Up to know the indications for the optimal applications of laboratory diagnosis of allergic diseases have become widely known. Measurements of allergy specific IgE and various tests of cell mediated immunity are included in the practice. It can be stated that measurements of total serum IgE and allergen specific IgE (kU/l and RAST classes) can be maintained further in the Hungarian practice with the expected continuous participation of all laboratories in the external quality control program (QualiCont). However, it is also apparent that regional introduction of the urgent "molecular (component) based allergy diagnostics" has become necessary for efficient allergen specific immunotherapy in Hungary. In cases of the allergen specific cell mediated immunologic reactions, allergen induced cell proliferation and cytokine release measurements are recommended. However, it is also obvious that application of these measurements in clinical practice need correct financial support from health care authorities.
authors.affiliation: Klinikai Immunológiai Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.
authors.forename: Sándor
authors.initials: S
authors.lastname: Sipka
mesh_terms: D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D006814:Hungary; D006967:Hypersensitivity / Q000175:diagnosis* / Q000266:history / Q000276:immunology*; D006968:Hypersensitivity, Delayed / Q000175:diagnosis / Q000276:immunology; D006969:Hypersensitivity, Immediate / Q000175:diagnosis / Q000276:immunology; D007073:Immunoglobulin E / Q000097:blood*; D007159:Immunologic Tests / Q000266:history / Q000592:standards / Q000639:trends; D059021:Laboratory Proficiency Testing
chemical_list: D007073:Immunoglobulin E
keywords: IgE; allergen specific immunotherapy; allergia; allergy; allergénspecifikus immunterápia; component based allergy therapy; komponensalapú allergiadiagnosztika; molecule based allergy therapy; molekuláris alapú allergiadiagnosztika