title: Primary dural lymphoma: Complete remission after treatment with radiation therapy.
abstract: Central nervous system (CNS) involvement in sarcoidosis is rare and typically occurs in 5-10% of patients. Neurological symptoms in a patient with known sarcoidosis can be attributed to neurosarcoidosis without thorough evaluation. Primary Dural Lymphoma (PDL) is an extremely rare form of non-Hodgkin lymphoma. Although PDL is technically a subtype of primary CNS lymphoma, the two entities vary markedly in their histological grade, clinical course, prognosis and treatment. The most common dural- based lesion found on CNS imaging is meningioma. It shares many imaging, clinical and epidemiologic features of PDL which often leads to misdiagnosis of PDL as meningioma. We present a case where a PDL was diagnosed after CNS symptoms failed to resolve after steroid therapy for presumed neurosarcoidosis.
authors.affiliation: UTSouthwestern Medical Center, Dallas, Texas. jeremy.jones@phhs.org.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Jones
authors.forename: Arjun
authors.initials: A
authors.lastname: Gupta
authors.forename: Harris
authors.initials: H
authors.lastname: Naina
mesh_terms: D001707:Biopsy, Needle; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy*; D004388:Dura Mater / Q000473:pathology* / Q000528:radiation effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D020522:Lymphoma, Mantle-Cell / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D035583:Rare Diseases; D016896:Treatment Outcome