title: [Non-invasive prenatal testing is a breakthrough in prenatal screening].
abstract: Non-invasive prenatal testing (NIPT) using cell-free fetal DNA from the peripheral blood of the pregnant woman has become a possibility within recent years, but is not yet implemented in Denmark. NIPT has proven to be very efficient in the screening for especially trisomi 21. This article summarizes the basics behinds the most used NIPT techniques and describes which genetic conditions this method may detect. Finally, the future aspects of implementing NIPT in the prenatal screening programme in Denmark are discussed.
authors.affiliation: Gynækologisk Obstetrisk Afdeling, Hvidovre Hospital, Kettegård Allé 30, 2650 Hvidovre. louisehornstrup@hotmail.com.
authors.forename: Louise Stig
authors.initials: LS
authors.lastname: Hornstrup
authors.forename: Louise
authors.initials: L
authors.lastname: Ambye
authors.forename: Steen
authors.initials: S
authors.lastname: Sørensen
authors.forename: Finn Stener
authors.initials: FS
authors.lastname: Jørgensen
mesh_terms: D002474:Cell-Free System; D004247:DNA / Q000097:blood; D003718:Denmark; D004314:Down Syndrome / Q000175:diagnosis / Q000235:genetics; D005260:Female; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D062145:Maternal Serum Screening Tests / Q000379:methods*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis / Q000379:methods*; D017422:Sequence Analysis, DNA
chemical_list: D004247:DNA