title: [ASSOCIATION OF ALLELE VARIANTS OF RECEPTOR GENE OF ANDROGENS (BY THE NUMBER OF CAG-REPEATS) WITH ANDROGEN DEPENDENT HORMONAL METABOLIC INDICES OF THE ORGANISM].
abstract: This review discusses up-to-date conceptions concerning an association of androgen receptor gene (AR) allele (by the number of CAG-repeats) variations with the change of the receptor activity in humans. Different contradictory experiment results concerning the AR function dependence on the number of CAG-repeats have been analyzed. The authors discuss this problem paying mostly their attention to the interrelation between the number of CAG-repeats and indicators of glucose and lipid metabolism in males and females.
authors.forename: V V
authors.initials: VV
authors.lastname: Korpachev
authors.forename: S V
authors.initials: SV
authors.lastname: Melnychenko
authors.forename: R G
authors.initials: RG
authors.lastname: Lukashova
mesh_terms: D000483:Alleles; D004958:Estradiol / Q000378:metabolism; D005260:Female; D005786:Gene Expression Regulation; D005947:Glucose / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D055503:Protein Multimerization; D011944:Receptors, Androgen / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D012737:Sex Factors; D015398:Signal Transduction; D013739:Testosterone / Q000378:metabolism*; D018911:Trinucleotide Repeats
chemical_list: D006360:Heat-Shock Proteins; D011944:Receptors, Androgen; D013739:Testosterone; D004958:Estradiol; D005947:Glucose