title: [The Impact of Late Umbilical Cord Clamping on Neonatal Jaundice and Postpartum Hemorrhage: A Randomized Controlled Trail].
abstract: BACKGROUND
  The current evidence supports the clinical benefits of late umbilical cord clamping. These benefits include increased blood volume and total body iron. Furthermore, delayed cord clamping facilitates the transplantation of stem cells, which helps the development of infant bodily systems. However, due to concerns related to postpartum hemorrhaging and neonate jaundice, most maternity units still clamp the cord immediately after a child is born.
  
  
  OBJECTIVE
  This study investigates the impact of delaying cord clamping on neonatal jaundice and postpartum hemorrhage.
  
  
  METHODS
  A randomized, controlled trial was conducted at a regional teaching hospital in northern Taiwan. One hundred and five healthy nulliparous women at 36 weeks of pregnancy were included and allocated randomly to the experiment group (n=44) and the control group (n=61). Participants in the experiment group received delayed cord clamping (DCC) at 3 minutes after delivery. Participants in the control group received early cord clamping (ECC) at around 1 minute after delivery. Clinical measures of the outcomes were measured by the infant transcutaneous bilirubin levels (TcB) and postpartum hemorrhage at birth. A structured questionnaire and biophysical measures were used to collect data on participant demographics, obstetrical information, maternal blood loss at birth, neonate weight and TcB level at hospitalization, and whether or not the infant received phototherapy at 4-7 days postpartum.
  
  
  RESULTS
  Overall, there was no significant difference between the two groups in terms of neonatal jaundice, maternal hemorrhage at birth, and phototherapy rates at time of hospitalization and at 4-7 days postpartum.
  
  
  CONCLUSIONS
  The findings of the present study support that late umbilical cord clamping does not increase the risk of maternal postpartum hemorrhaging or neonate jaundice. Thus, we suggest that clinicians inform clients during prenatal classes of the benefits of delayed cord clamping and also use current, evidence-based knowledge to dispel client worries regarding the dangers to maternal-neonate health of delayed cord clamping.
authors.affiliation: Department of Nursing, Taoyuan General Hospital, Ministry of Health and Welfare, Taiwan, ROC.
authors.forename: Pei-Chun
authors.initials: PC
authors.lastname: Chien
authors.affiliation: Department of Obstetrics and Gynecology, St. Paul's Hospital, Taiwan, ROC.
authors.forename: Cherng-Chia
authors.initials: CC
authors.lastname: Yang
authors.affiliation: Graduate Institute of Nurse-Midwifery, National Taipei University of Nursing and Health Sciences, Taiwan, ROC. meeiling@ntunhs.edu.tw.
authors.forename: Meei-Ling
authors.initials: ML
authors.lastname: Gau
authors.affiliation: Graduate Institute of Nurse-Midwifery, National Taipei University of Nursing and Health Sciences, Taiwan, ROC.
authors.forename: Chieh-Yu
authors.initials: CY
authors.lastname: Liu
authors.affiliation: School of Nursing, National Taipei University of Nursing and Health Sciences, Taiwan, ROC.
authors.forename: Tzu-Ying
authors.initials: TY
authors.lastname: Lee
mesh_terms: D003250:Constriction; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000209:etiology*; D006473:Postpartum Hemorrhage / Q000209:etiology*; D011247:Pregnancy; D014470:Umbilical Cord
keywords: delayed cord clamping; neonatal jaundice; postpartum hemorrhage