title: Electroencephalographic connectivity analysis in schizophrenia.
abstract: The aim of the present study was to further investigate the electroencephalogram (EEG) connectivity in schizophrenic patients by means of mutual information (MI), an analysis capable of detecting both the linear and nonlinear components of EEG. 19-lead EEGs were recorded in stable schizophrenic patients (N=17) and healthy controls (N=17) in two different conditions: closed eyes (CE) and open eyes (OE). In patients, higher MI values were observed in temporal-parietal-occipital regions compared with controls. In controls, an increase in brain connectivity in frontal regions was observed in the CE condition. This increase was not present in patients. Our results suggest that patients with schizophrenia present changes of brain connectivity that can be detected through MI analysis.
authors.affiliation: Department of Neuroscience, University of Turin Medical School, and National Institute of Neuroscience, Turin, Italy. Electronic address: elisa.carlino@unito.it.
authors.forename: Elisa
authors.initials: E
authors.lastname: Carlino
authors.affiliation: Department of Neuroscience, Psychiatric Section, University of Turin, Turin, Italy.
authors.forename: Monica
authors.initials: M
authors.lastname: Sigaudo
authors.affiliation: Department of Psychology, University of Turin, Turin, Italy.
authors.forename: Rosalba
authors.initials: R
authors.lastname: Rosato
authors.affiliation: Department of Neuroscience, University of Turin Medical School, and National Institute of Neuroscience, Turin, Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Vighetti
authors.affiliation: Department of Neuroscience, Psychiatric Section, University of Turin, Turin, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Rocca
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000503:physiopathology*; D055815:Young Adult
keywords: Electroencephalographic connectivity; Mutual information; Schizophrenia