title: [Adult onset Still's disease with small vessel vasculitis].
abstract: This article presents a particularly severe case of adult onset Still's disease aggravated by small vessel vasculitis. A satisfactory therapy was concluded 1.5 years after onset of the disease. The small vessel vasculitis was difficult to treat: methotrexate (MTX), cyclophosphamide and rituximab were not sufficiently effective. Tocilizumab in combination with intravenous immunoglobulin (IVIG) induced remission and maintenance therapy was carried out with tocilizumab.
authors.affiliation: Med. Klinik m. S. Rheumatologie und Klinische Immunologie, Charité Universitätsmedizin, Charitéplatz 1, 10117, Berlin, Deutschland, paula.hoff@charite.de.
authors.forename: P
authors.initials: P
authors.lastname: Hoff
authors.forename: B F
authors.initials: BF
authors.lastname: Hoyer
authors.forename: U
authors.initials: U
authors.lastname: Schneider
authors.forename: C
authors.initials: C
authors.lastname: Kneitz
authors.forename: G-R
authors.initials: GR
authors.lastname: Burmester
authors.forename: F
authors.initials: F
authors.lastname: Buttgereit
mesh_terms: D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008297:Male; D016706:Still's Disease, Adult-Onset / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; C502936:tocilizumab