title: [Efficacy of splenic artery trunk embolization with detachable balloon for portal hypertension and hypersplenism].
abstract: OBJECTIVE
  To investigate the efficacy of detachable balloon for splenic artery trunk embolization in patients with cirrhotic portal hypertension and hypersplenism.
  
  
  METHODS
  Eight patients with cirrhotic portal hypertension received splenic artery trunk disconnection using detachable balloons under the guidance of digital subtraction angiography. The diameter and blood flow of the portal vein, the superior mesenteric vein, the splenic vein and the hepatic artery were measured by color Doppler ultrasound. Markers of liver function and blood coagulation, and routine blood parameters were assessed. Gastroscopy was used to evaluate to the degree of gastroesophageal varices. All complications experienced during the perioperative period were recorded.
  
  
  RESULTS
  The portal vein diameter decreased from 1.55±0.38 cm to 1.55±0.38 cm, and the splenic artery diameter decreased from 1.45±0.10 cm to 1.41±0.09 cm (P < 0.05). The portal vein blood flow was reduced from 971.52±174.77 ml/min to 785.86±100.17 ml/min, and the splenic vein blood flow decreased from 938.01±208.86 ml/min to 644.02±188.15 ml/min, while the hepatic artery blood flow increased from 261.25±65.47 ml/min to 449.32±84.05 ml/min (P < 0.05). The symptoms of splenism were improved effectively, with platelet counts rising from 37.75±10.61*109/L to 138.63±28.22*109/L after the procedure (P < 0.05). There were no episodes of severe complications or death in the perioperative period, and all patients showed remarkable improvement in markers of liver function and coagulation function, and improvement of esophagogastric varices.
  
  
  CONCLUSIONS
  The interventional disconnection technique of the splenic artery trunk using detachable balloon for the treatment of portal hypertension and hypersplenism is safe and effective.
authors.affiliation: Department of Interventional Radiology, Affiliated Hospital of Qingdao University, Qingdao 266003, China.
authors.forename: Chengen
authors.initials: C
authors.lastname: Wang
authors.forename: Chengjian
authors.initials: C
authors.lastname: Sun
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Wang
authors.forename: Tonghui
authors.initials: T
authors.lastname: Liu
authors.forename: Lingling
authors.initials: L
authors.lastname: Xie
authors.forename: Weichao
authors.initials: W
authors.lastname: Ren
mesh_terms: D015901:Angiography, Digital Subtraction; D004621:Embolization, Therapeutic; D004932:Esophageal and Gastric Varices; D006439:Hemodynamics; D006499:Hepatic Artery; D006801:Humans; D006971:Hypersplenism; D006975:Hypertension, Portal; D008642:Mesenteric Veins; D010976:Platelet Count; D011169:Portal Vein; D013157:Splenic Artery