title: Acute kidney injury in patients with acute coronary syndromes.
abstract: Acute kidney injury (AKI) is increasingly being seen in patients with acute coronary syndromes (ACSs). This condition has a complex pathogenesis, an incidence that can reach 30% and it is associated with higher short-term and long-term morbidity and mortality. Nevertheless, AKI is still characterised by lack of a single accepted definition, unclear pathophysiology understanding and insensitive diagnostic tools that make its detection difficult, particularly in the setting of ACS. Recent data suggested that patients with AKI during ACS, even those in whom renal function seems to fully recover, face an increased, persisting risk of future AKI and may develop chronic kidney disease. Thus, in these patients, nephrology follow-up, after hospital discharge, and secondary preventive measures should possibly be implemented. In this review, we aim at providing a framework of knowledge to increase cardiologists' awareness of AKI, with the goal of improving the outcome of patients with ACS.
authors.affiliation: Centro Cardiologico Monzino, I.R.C.C.S., University of Milan, Milan, Italy.
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Marenzi
authors.affiliation: Centro Cardiologico Monzino, I.R.C.C.S., University of Milan, Milan, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Cosentino
authors.affiliation: Centro Cardiologico Monzino, I.R.C.C.S., University of Milan, Milan, Italy.
authors.forename: Antonio L
authors.initials: AL
authors.lastname: Bartorelli
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000150:complications*; D058186:Acute Kidney Injury / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D002908:Chronic Disease; D003404:Creatinine / Q000378:metabolism; D018450:Disease Progression; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology; D009203:Myocardial Infarction / Q000150:complications; D011379:Prognosis; D009626:Terminology as Topic
chemical_list: D003404:Creatinine