title: [S3 Guideline. Part 3: Non-Traumatic Avascular Necrosis in Adults - Surgical Treatment of Atraumatic Avascular Femoral Head Necrosis in Adults].
abstract: The present article describes the guidelines for the surgical treatment of atraumatic avascular necrosis (aFKN). These include joint preserving and joint replacement procedures. As part of the targeted literature, 43 publications were included and evaluated to assess the surgical treatment. According to the GRADE and SIGN criteria level of evidence (LoE), grade of recommendation (EC) and expert consensus (EK) were listed for each statement and question. The analysed studies have shown that up to ARCO stage III, joint-preserving surgery can be performed. A particular joint-preserving surgery currently cannot be recommended as preferred method. The selection of the method depends on the extent of necrosis. Core decompression performed in stage ARCO I (reversible early stage) or stage ARCO II (irreversible early stage) with medial or central necrosis with an area of less than 30 % of the femoral head shows better results than conservative therapy. In ARCO stage III with infraction of the femoral head, the core decompression can be used for a short-term pain relief. For ARCO stage IIIC or stage IV core decompression should not be performed. In these cases, the indication for implantation of a total hip replacement should be checked. Additional therapeutic procedures (e.g., osteotomies) and innovative treatment options (advanced core decompression, autologous bone marrow, bone grafting, etc.) can be discussed in the individual case. In elective hip replacement complications and revision rates have been clearly declining for decades. In the case of an underlying aFKN, however, previous joint-preserving surgery (osteotomies and grafts in particular) can complicate the implantation of a THA significantly. However, the implant life seems to be dependent on the aetiology. Higher revision rates for avascular necrosis are particularly expected in sickle cell disease, Gaucher disease, or kidney transplantation patients. Furthermore, the relatively young age of the patient with avascular necrosis should be seen as the main risk factor for higher revision rate. The results after resurfacing (today with known restricted indications) and cemented as well as cementless THA in aFKN are comparable for the appropriate indication to those in coxarthrosis or other diagnoses. Regardless of the underlying disease endoprosthetic treatment in aFKN leads to good results. Both cemented and cementless fixation techniques can be recommended.
authors.affiliation: Klinik für Orthopädie und orthopädische Chirurgie, Universitätsklinik für Orthopädie und Unfallchirurgie, Pius-Hospital, Oldenburg.
authors.forename: U
authors.initials: U
authors.lastname: Maus
authors.affiliation: Klinik und Poliklinik für Orthopädie, Unfallchirurgie und Plastische Chirurgie, Universitätsklinik Leipzig AöR.
authors.forename: A
authors.initials: A
authors.lastname: Roth
authors.affiliation: Orthopaedic Surgery, University of Aachen.
authors.forename: M
authors.initials: M
authors.lastname: Tingart
authors.affiliation: Praxisklinik Orthopädie Aachen, Franziskushospital Aachen.
authors.forename: C
authors.initials: C
authors.lastname: Rader
authors.affiliation: Klinik für Orthopädie und Unfallchirurgie, Universität Duisburg-Essen.
authors.forename: M
authors.initials: M
authors.lastname: Jäger
authors.affiliation: Klinik für Orthopädie und Unfallchirurgie, Evangelisches Waldkrankenhaus Spandau.
authors.forename: U
authors.initials: U
authors.lastname: Nöth
authors.affiliation: Orthopädische Klinik König-Ludwig-Haus, Julius-Maximilians-Universität Würzburg.
authors.forename: S
authors.initials: S
authors.lastname: Reppenhagen
authors.affiliation: Klinik für Unfallchirurgie, Universitätsklinikum Gießen.
authors.forename: C
authors.initials: C
authors.lastname: Heiss
authors.affiliation: Sektion Endoprothetik, Sportklinik Stuttgart.
authors.forename: J
authors.initials: J
authors.lastname: Beckmann
mesh_terms: D019643:Arthroplasty, Replacement / Q000592:standards*; D003131:Combined Modality Therapy / Q000592:standards; D019299:Decompression, Surgical / Q000592:standards; D019317:Evidence-Based Medicine; D005260:Female; D005264:Femoral Fractures / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D005271:Femur Head Necrosis / Q000175:diagnosis* / Q000601:surgery*; D005858:Germany; D006801:Humans; D007595:Joint Prosthesis / Q000592:standards; D008297:Male; D059351:Organ Sparing Treatments / Q000295:instrumentation / Q000379:methods; D009985:Orthopedics / Q000592:standards*; D010027:Osteotomy / Q000592:standards*; D017410:Practice Guidelines as Topic; D012086:Reoperation / Q000592:standards; D016896:Treatment Outcome