title: Norepinephrine and Corticotropin-Releasing Hormone: Partners in the Neural Circuits that Underpin Stress and Anxiety.
abstract: Norepinephrine and corticotropin-releasing hormone (CRH) have long been implicated in the response to stress. In this issue of Neuron, McCall et al. (2015) show that CRH projections from the central amygdala drive tonic locus coeruleus activity that evokes acute anxiety responses and place aversion.
authors.affiliation: Queensland Brain Institute, University of Queensland, St. Lucia, QLD 4072, Australia.
authors.forename: Yajie
authors.initials: Y
authors.lastname: Sun
authors.affiliation: Queensland Brain Institute, University of Queensland, St. Lucia, QLD 4072, Australia.
authors.forename: Sarah
authors.initials: S
authors.lastname: Hunt
authors.affiliation: Queensland Brain Institute, University of Queensland, St. Lucia, QLD 4072, Australia. Electronic address: pankaj.sah@uq.edu.au.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Sah
mesh_terms: D059331:Adrenergic Neurons / Q000378:metabolism*; D000818:Animals; D001007:Anxiety / Q000378:metabolism*; D003346:Corticotropin-Releasing Hormone / Q000378:metabolism*; D008125:Locus Coeruleus / Q000378:metabolism*; D008297:Male; D013315:Stress, Psychological / Q000378:metabolism*
chemical_list: D003346:Corticotropin-Releasing Hormone