title: Treatment with mild brain hypothermia for cardiopulmonary resuscitation after myoclonic seizures in infant with robertsonian type of trisomy 13.
abstract: Congenital chromosomal abnormality with trisomy 13 is known to be associated with poor life prognosis and lethal. Therefore, physician advice the patients be kept in intensive treatment with resuscitation and state of the art intensive care when sudden change in the general condition with this trisomy is observed. We report herein, the treatment with mild brain hypothermia therapy for cardiopulmonary resuscitation after myoclonic seizures in infant with Robertsonian type of trisomy 13 in intensive care unit. Our study indicated that brain hypothermia therapy and steroid pulse therapy on an infant who was believed to have post-resuscitation hypoxic encephalopathy was highly effective as the patient's general condition recovered to the original state after four months.
authors.affiliation: Department of Pediatrics, Dokkyo Medical University School of Medicine, Tochigi, Japan. geo@dokkyomed.ac.jp.
authors.forename: G
authors.initials: G
authors.lastname: Imataka
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuboi
authors.forename: Y
authors.initials: Y
authors.lastname: Kano
authors.forename: K
authors.initials: K
authors.lastname: Ogino
authors.forename: T
authors.initials: T
authors.lastname: Tsuchioka
authors.forename: T
authors.initials: T
authors.lastname: Ohnishi
authors.forename: Y
authors.initials: Y
authors.lastname: Kaji
authors.forename: K
authors.initials: K
authors.lastname: Wake
authors.forename: G
authors.initials: G
authors.lastname: Ichikawa
authors.forename: H
authors.initials: H
authors.lastname: Suzumura
authors.forename: O
authors.initials: O
authors.lastname: Arisaka
mesh_terms: D001921:Brain / Q000473:pathology*; D016887:Cardiopulmonary Resuscitation / Q000009:adverse effects*; D025063:Chromosome Disorders / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D002882:Chromosomes, Human, Pair 13 / Q000235:genetics; D004831:Epilepsies, Myoclonic / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D005260:Female; D006323:Heart Arrest / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods*; D002534:Hypoxia, Brain / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D007223:Infant; D016896:Treatment Outcome; D014314:Trisomy / Q000175:diagnosis / Q000235:genetics; D000073839:Trisomy 13 Syndrome