title: Cu(II)-Mediated C(sp(2))-H Hydroxylation.
abstract: A Cu(II)-mediated ortho-C-H hydroxylation using a removable directing group has been developed. The reaction exhibits considerable functional group tolerance. The use of O2 as an oxidant is crucial for the reactivity. Water is also found to significantly improve this reaction.
authors.affiliation: Department of Chemistry, Innovative Drug Research Center, Shanghai University , 99 Shangda Road, Shanghai 200444, China.
authors.forename: Shang-Zheng
authors.initials: SZ
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Shang
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors.forename: Hong-Li
authors.initials: HL
authors.lastname: Wang
authors.affiliation: Department of Chemistry, Innovative Drug Research Center, Shanghai University , 99 Shangda Road, Shanghai 200444, China.
authors.forename: Hai-Xia
authors.initials: HX
authors.lastname: Lin
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors.forename: Hui-Xiong
authors.initials: HX
authors.lastname: Dai
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.|Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu