title: Combined effects of photodynamic therapy and irrigants in disinfection of root canals.
abstract: In this study, the combined effects of photodynamic therapy and irrigants in eradicating common endodontic pathogens are evaluated. Roots of 80 extracted single rooted teeth are divided into 2 groups (1) mechanical flushing; (2) antibacterial irrigation. After cleaning and shaping, they are inoculated with either (A) Streptococcus mutans or (B) Enterococcus faecalis and incubated. They are again subdivided and either only irrigated or irrigated and lased. Dentin shavings are taken from root canal walls and cultured. Statistical analysis using One-Way ANOVA and Post-hoc tests are done. The combination eradicated both bacteria. Antibacterial irrigants controlled S. mutans better than PDT (p = 0.041). The combination of PDT and antibacterial irrigation proposed in this study can be used in all primary cases for thorough and reliable disinfection of root canals but may be highly effective in resistant cases like endodontic failures, as E. faecalis is prevalent in such cases.
authors.affiliation: Department of Conservative Dentistry & Endodontics, Saveetha Dental College, Chennai, 600077, India. drsusila2000@yahoo.com.|Madha Dental College, Kundrathur, Chennai, 600069, India. drsusila2000@yahoo.com.
authors.forename: Anand V
authors.initials: AV
authors.lastname: Susila
authors.affiliation: Department of Conservative Dentistry & Endodontics, Saveetha Dental College, Chennai, 600077, India.
authors.forename: R
authors.initials: R
authors.lastname: Sugumar
authors.affiliation: Department of Conservative Dentistry & Endodontics, Saveetha Dental College, Chennai, 600077, India.
authors.forename: C S
authors.initials: CS
authors.lastname: Chandana
authors.affiliation: Department of Conservative Dentistry & Endodontics, Saveetha Dental College, Chennai, 600077, India.
authors.forename: C V
authors.initials: CV
authors.lastname: Subbarao
mesh_terms: D003786:Dental Pulp Cavity / Q000503:physiopathology*; D004203:Disinfection / Q000379:methods*; D006801:Humans; D010778:Photochemotherapy; D012388:Root Canal Irrigants / Q000627:therapeutic use*; D012973:Sodium Hypochlorite; D007507:Therapeutic Irrigation
chemical_list: D012388:Root Canal Irrigants; D012973:Sodium Hypochlorite
keywords: Antimicrobial; E. faecalis; S. mutans; debridement; endodontic failure; persistent infection; resistant