title: Complications secondary to cosmetic artificial iris anterior chamber implants: a case report.
abstract: BACKGROUND
  Artificial iris anterior chamber implants were originally developed for therapeutic purposes but have been used recently for the cosmetic alteration of eye colour. There is a growing body of evidence surrounding their associated risks. We report a case presenting with complications secondary to bilateral NewColorIris® implants, including the first report of pressure-induced stromal keratopathy in this context.
  
  
  METHODS
  A thirty-eight year old South American man presented as an emergency in the UK with best corrected visual acuities of 1/60 OD and 6/18 OS, bilateral corneal decompensation, lens opacities and raised intraocular pressures 4 years following bilateral NewColorIris® implantation in Panama. Anterior segment optical coherence tomography demonstrated the direct apposition of the implant with the iris and iridocorneal angle, together with pressure-induced stromal keratopathy with a fluid interface between the corneal stroma and previous laser-assisted in situ keratomileusis flaps. We describe the successful combined medical and surgical management in this case to yield a final visual acuity 6/12 in both eyes.
  
  
  CONCLUSIONS
  Artificial iris anterior chamber implants are associated with sight-threatening complications that can present years after their implantation. We caution against their use for the cosmetic alteration of eye colour.
authors.affiliation: Moorfields Eye Hospital, London, UK. yusrahsh@gmail.com.
authors.forename: Yusrah
authors.initials: Y
authors.lastname: Shweikh
authors.affiliation: Moorfields Eye Hospital, London, UK. sallyameen@yahoo.co.uk.
authors.forename: Sally
authors.initials: S
authors.lastname: Ameen
authors.affiliation: Imperial College Healthcare NHS Trust, Charing Cross Hospital, Fulham Palace Road, W6 8RF, London, UK. ali.mearza@imperial.nhs.uk.
authors.forename: Ali
authors.initials: A
authors.lastname: Mearza
mesh_terms: D000328:Adult; D000867:Anterior Chamber / Q000601:surgery*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001187:Artificial Organs; D003316:Corneal Diseases / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D005901:Glaucoma / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure; D007498:Iris; D008297:Male; D019736:Prostheses and Implants / Q000009:adverse effects*; D041623:Tomography, Optical Coherence
chemical_list: D000959:Antihypertensive Agents