title: Nasal Cavity Masses Resembling Chondro-osseous Respiratory Epithelial Adenomatoid Hamartomas in 3 Dogs.
abstract: Chondro-osseous respiratory epithelial adenomatoid hamartomas (COREAHs) are rare tumors in the nasal cavity of people, which have not been described in other species. COREAHs in people are minimally invasive and rarely recur following excision. Histologically, these tumors are composed of disorganized, mature, nasal turbinate tissue that is organized into polypoid growths. These growths are lined by respiratory epithelium, contain glandular elements, and are organized around central cores of chondro-osseous matrix. This report describes 3 cases of dogs with nasal tumors that have histomorphology similar to that of COREAH in people. The tumors were all identified within the nasal cavity and were associated with regional bony lysis of the turbinates and surrounding skull bones, a feature that has not been reported in COREAH in people. There was no evidence of metastasis or extension beyond the nasal cavity in any of the 3 cases.
authors.affiliation: University of California, School of Veterinary Medicine, Davis, CA, USA eladouceur@ucdavis.edu.
authors.forename: E E B
authors.initials: EE
authors.lastname: LaDouceur
authors.affiliation: University of California, School of Veterinary Medicine, Davis, CA, USA.
authors.forename: A O
authors.initials: AO
authors.lastname: Michel
authors.affiliation: University of California, School of Veterinary Medicine, Davis, CA, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Lindl Bylicki
authors.affiliation: University of Chile, Faculty of Veterinary and Animal Sciences, Santa Rosa, La Pintana, Santiago, Chile.
authors.forename: F F
authors.initials: FF
authors.lastname: Cifuentes
authors.affiliation: University of California, School of Veterinary Medicine, Davis, CA, USA.
authors.forename: V K
authors.initials: VK
authors.lastname: Affolter
authors.affiliation: University of California, School of Veterinary Medicine, Davis, CA, USA.
authors.forename: B G
authors.initials: BG
authors.lastname: Murphy
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D000818:Animals; D001842:Bone and Bones / Q000473:pathology; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D005260:Female; D006222:Hamartoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008297:Male; D009296:Nasal Cavity / Q000473:pathology; D009668:Nose Diseases / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D020545:Respiratory Mucosa / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000662:veterinary
keywords: dog; epistaxis; exophthalmos; hamartoma; histology; nasal sinus; pathology; respiratory