title: Cooperative Multicatalytic System for the One-Pot Synthesis of Octahydrospiro-β-carbolines.
abstract: A domino cyclization of 3-((3-(2-aminophenyl)prop-2-ynylamino)methyl)but-3-en-1-ol with aldehydes has been accomplished employing 5 mol % of the Ph3PAuCl/AgSbF6/In(OTf)3 system to afford the corresponding octahydrospiro[pyran-4,4'-pyrido[3,4-b]indole] derivatives in good yields with high selectivity. This is the first report on the synthesis of spiro-β-carbolines through a multicatalytic cascade process.
authors.affiliation: Natural Product Chemistry, ‡Laboratory of X-ray Crystallography, CSIR-Indian Institute of Chemical Technology , Hyderabad - 500 007, India.
authors.forename: B V
authors.initials: BV
authors.lastname: Subba Reddy
authors.affiliation: Natural Product Chemistry, ‡Laboratory of X-ray Crystallography, CSIR-Indian Institute of Chemical Technology , Hyderabad - 500 007, India.
authors.forename: M
authors.initials: M
authors.lastname: Rajashekhar Reddy
authors.affiliation: Natural Product Chemistry, ‡Laboratory of X-ray Crystallography, CSIR-Indian Institute of Chemical Technology , Hyderabad - 500 007, India.
authors.forename: Suresh
authors.initials: S
authors.lastname: Yarlagadda
authors.affiliation: Natural Product Chemistry, ‡Laboratory of X-ray Crystallography, CSIR-Indian Institute of Chemical Technology , Hyderabad - 500 007, India.
authors.forename: C
authors.initials: C
authors.lastname: Ravikumar Reddy
authors.affiliation: Natural Product Chemistry, ‡Laboratory of X-ray Crystallography, CSIR-Indian Institute of Chemical Technology , Hyderabad - 500 007, India.
authors.forename: G
authors.initials: G
authors.lastname: Ravi Kumar
authors.affiliation: Natural Product Chemistry, ‡Laboratory of X-ray Crystallography, CSIR-Indian Institute of Chemical Technology , Hyderabad - 500 007, India.
authors.forename: J S
authors.initials: JS
authors.lastname: Yadav
authors.affiliation: Natural Product Chemistry, ‡Laboratory of X-ray Crystallography, CSIR-Indian Institute of Chemical Technology , Hyderabad - 500 007, India.
authors.forename: B
authors.initials: B
authors.lastname: Sridhar