title: Electrochemically triggered release of human insulin from an insulin-impregnated reduced graphene oxide modified electrode.
abstract: An electrochemical insulin-delivery system based on reduced graphene oxide impregnated with insulin is described. Upon application of a potential pulse of -0.8 V for 30 min, up to 70 ± 4% of human insulin was released into a physiological medium while preserving its biological activity.
authors.affiliation: Institute d'Electronique, de Microélectronique et de Nanotechnologie (IEMN, UMR CNRS 8520), Université Lille 1, Cité Scientifique, Avenue Poincaré, BP 60069, 59652 Villeneuve d'Ascq, France. sabine.szunerits@iri.univ-lille1.fr.
authors.forename: Florina
authors.initials: F
authors.lastname: Teodorescu
authors.forename: Laure
authors.initials: L
authors.lastname: Rolland
authors.forename: Viswanatha
authors.initials: V
authors.lastname: Ramarao
authors.forename: Amar
authors.initials: A
authors.lastname: Abderrahmani
authors.forename: Daniel
authors.initials: D
authors.lastname: Mandler
authors.forename: Rabah
authors.initials: R
authors.lastname: Boukherroub
authors.forename: Sabine
authors.initials: S
authors.lastname: Szunerits
mesh_terms: D055664:Electrochemical Techniques; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D007328:Insulin / Q000737:chemistry*; D015394:Molecular Structure; D010087:Oxides / Q000737:chemistry*; D010316:Particle Size; D013499:Surface Properties
chemical_list: D007328:Insulin; D010087:Oxides; D006108:Graphite