title: Comparison of Energy Expenditure and Oxygen Consumption of Spontaneous Breathing Trial Conducted With and Without Automatic Tube Compensation.
abstract: BACKGROUND
  Weaning from mechanical ventilation is defined as the process of release of ventilatory support and how the evaluation of this phase is conducted in the spontaneous breathing trial (SBT). One of the most used modes of SBT is the continuous positive airway pressure (CPAP), which applies a continuous positive pressure in both inspiration and expiration. However, together with the mechanical ventilation modes, the automatic tube compensation (ATC) can be used, which compensates the resistance imposed by the endotracheal tube. The objective of this study was to compare oxygen consumption (VO2) and energy expenditure (EE) during SBT conducted with and without ATC.
  
  
  METHODS
  The study was prospective, randomized and crossover. Forty mechanically ventilated patients were admitted to an intensive care unit of a university tertiary hospital. The participants were randomly allocated in group 1, in which SBT was initiated with CPAP and ATC, followed by CPAP without ATC or in group 2, in which SBT was initiated with CPAP without ATC, followed by CPAP with ATC. Indirect calorimetry helped to measure VO2 and EE during SBT.
  
  
  RESULTS
  The differences between VO2 and EE obtained during SBT with ATC and without ATC were -1.6 mL/kg/min (95% CI: -4.36 - 1.07) and 5.4 kcal/day (95% CI: -21.67 - 10.79), respectively.
  
  
  CONCLUSIONS
  We concluded that VO2 and EE obtained during SBT with and without ATC were not different.
authors.affiliation: Division of Intensive Care, Department of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Alessandra Fabiane
authors.initials: AF
authors.lastname: Lago
authors.affiliation: Division of Intensive Care, Department of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Elaine Cristina
authors.initials: EC
authors.lastname: Goncalves
authors.affiliation: Division of Intensive Care, Department of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Elaine Caetano
authors.initials: EC
authors.lastname: Silva
authors.affiliation: Division of Intensive Care, Department of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Mayra Goncalves
authors.initials: MG
authors.lastname: Menegueti
authors.affiliation: Division of Intensive Care, Department of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Edson Antonio
authors.initials: EA
authors.lastname: Nicolini
authors.affiliation: Division of Intensive Care, Department of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Maria
authors.initials: M
authors.lastname: Auxiliadora-Martins
authors.affiliation: Department of Social Medicine, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Edson Zangiacomi
authors.initials: EZ
authors.lastname: Martinez
authors.affiliation: Department of Physiotherapy, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Ada Clarice
authors.initials: AC
authors.lastname: Gastaldi
authors.affiliation: Division of Intensive Care, Department of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, SP 14049-900 Ribeirao Preto, Brazil.
authors.forename: Anibal
authors.initials: A
authors.lastname: Basile-Filho
keywords: Artificial respiration; Indirect calorimetry; Intensive care units; Respiratory insufficiency; Ventilator weaning