title: Risks and benefits in treatment of mediastinal abscess by endobronchial ultrasound-guided transbronchial needle aspiration.
abstract: BACKGROUND
  Mediastinal abscess is a fatal condition, treatment of mediastinal abscess is with antibiotics and sometimes surgery for debridement and drainage. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a safe assessment and candidate treatment method of mediastinal lesions.
  
  
  OBJECTIVE
  This study aimed to HYPERLINK "javascript:void(0);" discuss risks and benefits in treatment of mediastinal abscess by EBUS-TBNA.
  
  
  METHODS
  We noticed a 56-year-old man with developed bilateral pneumonia and sepsis after puncture of mediastinal abscess by EBUS-TBNA. The patient was successfully treated with a combination of systemic anti-infection treatment and intracavitary administration of antibiotics, antifungal and repeated drainage and lavage via EBUS-TBNA, in 1 year follow-up without recurrence.
  
  
  RESULTS
  This study indicated infection spread risk of mediastinal abscess after EBUS-TBNA, and mediastinal abscess was successfully cured by combination of systemic anti-infection and local intervention through EBUS-TBNA.
  
  
  CONCLUSIONS
  EBUS-TBNA is a potential effective minimally invasive treatment for mediastinal abscess, and it is necessary to be aware of clinical complications after puncture of mediastinal infectious lesions by EBUS-TBNA.
authors.affiliation: Departments of Endoscopy and Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.|Department of Thoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Tian
authors.affiliation: The Angelos Center for Lung Disease, Medstar Franklin Square Hospital Center, Baltimore, MD, USA.
authors.forename: William S
authors.initials: WS
authors.lastname: Krimsky
authors.affiliation: Department of Thoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Qingchen
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Departments of Endoscopy and Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Jiayuan
authors.initials: J
authors.lastname: Sun
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D044963:Biopsy, Fine-Needle / Q000379:methods*; D004322:Drainage / Q000379:methods; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D008297:Male; D008477:Mediastinal Diseases / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology* / Q000601:surgery; D008482:Mediastinum / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications; D018570:Risk Assessment; D018805:Sepsis / Q000150:complications; D015898:Tomography Scanners, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography / Q000295:instrumentation*; D018084:Ultrasonography, Interventional / Q000009:adverse effects / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents
keywords: abscess - EBUS-TBNA - pneumonia - sepsis - mediastinum