title: Cytosolic BMAL1 moonlights as a translation factor.
abstract: It is widely recognized that BMAL1 is an essential subunit of the primary transcription factor that drives rhythmic circadian transcription in the nucleus. In a surprising turn, Lipton et al. now show that BMAL1 rhythmically interacts with translational machinery in the cytosol to stimulate protein synthesis in response to mTOR signaling.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA.
authors.forename: Alicia K
authors.initials: AK
authors.lastname: Michael
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA.
authors.forename: Hande
authors.initials: H
authors.lastname: Asimgil
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA. Electronic address: cpartch@ucsc.edu.
authors.forename: Carrie L
authors.initials: CL
authors.lastname: Partch
mesh_terms: D056930:ARNTL Transcription Factors / Q000378:metabolism*; D000818:Animals; D057906:Circadian Clocks; D038744:Ribosomal Protein S6 Kinases, 90-kDa / Q000378:metabolism*
chemical_list: D056930:ARNTL Transcription Factors; D038744:Ribosomal Protein S6 Kinases, 90-kDa