title: Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea.
abstract: BACKGROUND
  The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea.
  
  
  METHODS
  To clarify the relationship between the onset of renal cell carcinoma in 52-years old male worker and the exposure to trichloroethylene, document studies and work environment measurement were done. Past work environment exposure data were reviewed and medical history and surgery records of the worker were also reviewed. The patient had no personal risk factor related to renal cell carcinoma except for his smoking habit of quarter a pack per day for twenty years, and since trichloroethylene was not part of measurement criteria, past work environment risk assessment data could not verify the exposure. The exposure level is deduced by analyzing material exposure level of work environments which has similar processes in data from revised research of chemical exposure standard and work environment validity assessment. Evaluation Committee of Epidemiologic Survey decided that there are relevant relationship between the exposure and the disease, though we do not have exact data during that period, most experts agree that in every factories they used trichloroethylene without any direction.
  
  
  CONCLUSIONS
  From the relevant medical history and the results of the usage of trichloroethylene in the relevant industries, and initial discovery of renal cell carcinoma at health inspection sonogram in 2001, it can be concluded that suggests significant causal relationship between the exposure to trichloroethylene and renal cell carcinoma onset, thus reporting it to be the first domestic case declared to be occupational disease.
authors.affiliation: Graduate School of Public Health, Yonsei University, 50 Seongsanno (134 Sinchon-dong), Seodaemun-gu, Seoul, South Korea ; The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: June-Hee
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Occupational and Environmental Medicine, Hanyang University College of Medicine, Seoul, South Korea.
authors.forename: Inah
authors.initials: I
authors.lastname: Kim
authors.affiliation: Graduate School of Public Health, Yonsei University, 50 Seongsanno (134 Sinchon-dong), Seodaemun-gu, Seoul, South Korea ; The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Hongdeok
authors.initials: H
authors.lastname: Seok
authors.affiliation: Graduate School of Public Health, Yonsei University, 50 Seongsanno (134 Sinchon-dong), Seodaemun-gu, Seoul, South Korea.
authors.forename: Inhyo
authors.initials: I
authors.lastname: Park
authors.affiliation: The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Jungho
authors.initials: J
authors.lastname: Hwang
authors.affiliation: Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency, Ulsan, South Korea.
authors.forename: Jae-Oh
authors.initials: JO
authors.lastname: Park
authors.affiliation: Graduate School of Public Health, Yonsei University, 50 Seongsanno (134 Sinchon-dong), Seodaemun-gu, Seoul, South Korea ; The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea ; Department of Preventive Medicine and Public Health, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Jong-Uk
authors.initials: JU
authors.lastname: Won
authors.affiliation: Graduate School of Public Health, Yonsei University, 50 Seongsanno (134 Sinchon-dong), Seodaemun-gu, Seoul, South Korea ; The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea ; Department of Preventive Medicine and Public Health, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Jaehoon
authors.initials: J
authors.lastname: Roh
keywords: Automobiles; Carcinoma; Korea; Occupational disease; Renal cell; Trichloroethylene