title: Development of grouped icEEG for the study of cognitive processing.
abstract: Invasive intracranial EEG (icEEG) offers a unique opportunity to study human cognitive networks at an unmatched spatiotemporal resolution. To date, the contributions of icEEG have been limited to the individual-level analyses or cohorts whose data are not integrated in any way. Here we discuss how grouped approaches to icEEG overcome challenges related to sparse-sampling, correct for individual variations in response and provide statistically valid models of brain activity in a population. By the generation of whole-brain activity maps, grouped icEEG enables the study of intra and interregional dynamics between distributed cortical substrates exhibiting task-dependent activity. In this fashion, grouped icEEG analyses can provide significant advances in understanding the mechanisms by which cortical networks give rise to cognitive functions.
authors.affiliation: Vivian Smith Department of Neurosurgery, University of Texas Health Science Center at Houston Houston, TX, USA.
authors.forename: Cihan M
authors.initials: CM
authors.lastname: Kadipasaoglu
authors.affiliation: Vivian Smith Department of Neurosurgery, University of Texas Health Science Center at Houston Houston, TX, USA.
authors.forename: Kiefer
authors.initials: K
authors.lastname: Forseth
authors.affiliation: Vivian Smith Department of Neurosurgery, University of Texas Health Science Center at Houston Houston, TX, USA ; Department of Computational and Applied Mathematics, Rice University Houston, TX, USA.
authors.forename: Meagan
authors.initials: M
authors.lastname: Whaley
authors.affiliation: Vivian Smith Department of Neurosurgery, University of Texas Health Science Center at Houston Houston, TX, USA.
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Conner
authors.affiliation: Vivian Smith Department of Neurosurgery, University of Texas Health Science Center at Houston Houston, TX, USA.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Rollo
authors.affiliation: Vivian Smith Department of Neurosurgery, University of Texas Health Science Center at Houston Houston, TX, USA.
authors.forename: Vatche G
authors.initials: VG
authors.lastname: Baboyan
authors.affiliation: Vivian Smith Department of Neurosurgery, University of Texas Health Science Center at Houston Houston, TX, USA ; Texas Medical Center, Mischer Neuroscience Institute, Memorial Hermann Hospital Houston, TX, USA.
authors.forename: Nitin
authors.initials: N
authors.lastname: Tandon
keywords: ECoG; cortical network dynamics; distributed cortical networks; face perception; fusiform face area (FFA); icEEG; parahippocampal place area (PPA); ventral temporal cortex