title: Malaria Epidemiology and Control Within the International Centers of Excellence for Malaria Research.
abstract: Understanding the epidemiological features and metrics of malaria in endemic populations is a key component to monitoring and quantifying the impact of current and past control efforts to inform future ones. The International Centers of Excellence for Malaria Research (ICEMR) has the opportunity to evaluate the impact of malaria control interventions across endemic regions that differ in the dominant Plasmodium species, mosquito vector species, resistance to antimalarial drugs and human genetic variants thought to confer protection from infection and clinical manifestations of plasmodia infection. ICEMR programs are conducting field studies at multiple sites with the aim of generating standardized surveillance data to improve the understanding of malaria transmission and to monitor and evaluate the impact of interventions to inform malaria control and elimination programs. In addition, these epidemiological studies provide a vast source of biological samples linked to clinical and environmental "meta-data" to support translational studies of interactions between the parasite, human host, and mosquito vector. Importantly, epidemiological studies at the ICEMR field sites are integrated with entomological studies, including the measurement of the entomological inoculation rate, human biting index, and insecticide resistance, as well as studies of parasite genetic diversity and antimalarial drug resistance.
authors.forename: William J
authors.initials: WJ
authors.lastname: Moss
authors.forename: Grant
authors.initials: G
authors.lastname: Dorsey
authors.forename: Ivo
authors.initials: I
authors.lastname: Mueller
authors.forename: Miriam K
authors.initials: MK
authors.lastname: Laufer
authors.forename: Donald J
authors.initials: DJ
authors.lastname: Krogstad
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Vinetz
authors.forename: Mitchel
authors.initials: M
authors.lastname: Guzman
authors.forename: Angel M
authors.initials: AM
authors.lastname: Rosas-Aguirre
authors.forename: Socrates
authors.initials: S
authors.lastname: Herrera
authors.forename: Myriam
authors.initials: M
authors.lastname: Arevalo-Herrera
authors.forename: Laura
authors.initials: L
authors.lastname: Chery
authors.forename: Ashwani
authors.initials: A
authors.lastname: Kumar
authors.forename: Pradyumna K
authors.initials: PK
authors.lastname: Mohapatra
authors.forename: Lalitha
authors.initials: L
authors.lastname: Ramanathapuram
authors.forename: H C
authors.initials: HC
authors.lastname: Srivastava
authors.forename: Liwang
authors.initials: L
authors.lastname: Cui
authors.forename: Guofa
authors.initials: G
authors.lastname: Zhou
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Parker
authors.forename: Joaniter
authors.initials: J
authors.lastname: Nankabirwa
authors.forename: James W
authors.initials: JW
authors.lastname: Kazura
authors.lastname: For The International Centers Of Excellence For Malaria Research
mesh_terms: D000818:Animals; D009033:Culicidae / Q000469:parasitology; D060740:Disease Eradication; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology; D007391:International Cooperation; D008288:Malaria / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D010961:Plasmodium; D011159:Population Surveillance