title: Clinicopathological significance of Melkersson-Rosenthal syndrome.
abstract: Melkersson-Rosenthal syndrome (MRS) classically shows a triad of orofacial swelling, fissured tongue and facial palsy, more commonly the oligosymptomatic form. The orofacial swelling is characterised by swollen reddish-brown non-pruritic lips and facial oedema. In one-third to one half of patients, fissured tongue is seen, which also aids in diagnosis. The histological finding of MRS includes non-caseating, sarcoidal granulomas, but their absence does not exclude the diagnosis. All these findings together form a basis for a cautious search for confrontational reasons for the symptom complex of MRS.
authors.affiliation: Department of Oral Pathology and Microbiology, Sharad Pawar Dental College, Wardha, Maharashtra, India.
authors.forename: Shruti
authors.initials: S
authors.lastname: Bohra
authors.affiliation: Department of Pedodontics and Preventive Dentistry, KM Shah Dental College and Hospital, Vadodara, Gujarat, India.
authors.forename: Pratik B
authors.initials: PB
authors.lastname: Kariya
authors.affiliation: Department of Pedodontics and Preventive Dentistry, KM Shah Dental College and Hospital, Vadodara, Gujarat, India.
authors.forename: Seema Dinesh
authors.identifier: http://orcid.org/0000-0003-4110-7990
authors.initials: SD
authors.lastname: Bargale
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Gandhinagar, Gujarat, India.
authors.forename: Shital
authors.initials: S
authors.lastname: Kiran
mesh_terms: D000293:Adolescent; D002613:Cheilitis / Q000209:etiology* / Q000473:pathology; D003937:Diagnosis, Differential; D004487:Edema / Q000209:etiology*; D005260:Female; D005882:Gingival Diseases / Q000209:etiology*; D006801:Humans; D008556:Melkersson-Rosenthal Syndrome / Q000175:diagnosis*; D014063:Tongue, Fissured / Q000209:etiology*