title: A new oxolane from Enterobacter cloacae.
abstract: Enterobacter cloacae is a highly pathogenic Gram-negative proteobacterium which is responsible for a wide array of infections. In the present study, the fermentation culture of E. cloacae has yielded one new oxolane compound, Rimboxo (1) in addition to three known compounds, i.e. Maculosine (2), phenylacetic acid (3) and methyl myristate (4). These compounds were isolated and characterised using extensive chromatographic and spectroscopic methods, and were subjected to cytotoxicity evaluations.
authors.affiliation: a Faculty of Science, Chemistry Department , University of Malaya , Kuala Lumpur 50603 , Malaysia.
authors.forename: Ann-Chee
authors.initials: AC
authors.lastname: Yap
authors.affiliation: b Faculty of Science, Institute of Biological Sciences, University of Malaya , Kuala Lumpur 50603 , Malaysia.
authors.forename: Kok-Gan
authors.initials: KG
authors.lastname: Chan
authors.affiliation: b Faculty of Science, Institute of Biological Sciences, University of Malaya , Kuala Lumpur 50603 , Malaysia.
authors.forename: Kae-Shin
authors.initials: KS
authors.lastname: Sim
authors.affiliation: a Faculty of Science, Chemistry Department , University of Malaya , Kuala Lumpur 50603 , Malaysia.
authors.forename: Yeun-Mun
authors.initials: YM
authors.lastname: Choo
mesh_terms: D045744:Cell Line, Tumor; D004148:Dioxolanes / Q000737:chemistry* / Q000302:isolation & purification; D016972:Enterobacter cloacae / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D013876:Thiophenes / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D004148:Dioxolanes; D013876:Thiophenes; C000598303:rimboxa; C000610652:rimboxo
keywords: Enterobacter cloacae; Rimboxo; oxolane; spectroscopic analysis