title: Synthesis of Vinyl Chlorides via Triphosgene-Pyridine Activation of Ketones.
abstract: Herein, we describe a mild method to prepare aliphatic and aromatic vinyl chlorides from their corresponding ketones via triphosgene-pyridine activation in dichloromethane at reflux. The mechanism of this reaction is proposed to involve formation of a putative α-chloro pyridinium carbamate intermediate, which appeared to readily undergo E2 elimination in the presence of pyridine.
authors.affiliation: Department of Chemistry, Louisiana State University , 232 Choppin Hall, Baton Rouge, Louisiana 70803, United States.
authors.forename: Mirza A
authors.initials: MA
authors.lastname: Saputra
authors.affiliation: Department of Chemistry, Louisiana State University , 232 Choppin Hall, Baton Rouge, Louisiana 70803, United States.
authors.forename: Ly
authors.initials: L
authors.lastname: Ngo
authors.affiliation: Department of Chemistry, Louisiana State University , 232 Choppin Hall, Baton Rouge, Louisiana 70803, United States.
authors.forename: Rendy
authors.initials: R
authors.lastname: Kartika