title: [Diagnostic workup of fragrance allergy].
abstract: The diagnostic workup of contact allergy to fragrances must not be limited to patch testing with the two well-established fragrance mixes. False-positive reactions to these mixes occur in up to 50 % of the patch tested patients. For the diagnostic work-up of positive reactions, and in cases of suspected fragrance allergy, patch testing with the single mix components and additional fragrances is mandatory. Frequently sensitizing fragrance materials are the 14 components of the two fragrance mixes and tree moss (Evernia furfuracea), ylang ylang oil (I + II; Cananga odorata), lemongrass oil (Cymbopogon schoenanthus), sandalwood oil (Santalum album), jasmine absolute (Jasminum spp.), and, less frequently, clove oil (Eugenia caryophyllus), cedarwood oil (Cedrus atlantica/deodara, Juniperus virginiana), Neroli oil (Citrus aurantium amara flower oil), salicylaldehyde, narcissus absolute (Narcissus spp.), and patchouli oil (Pogostemon cablin).
authors.affiliation: Informationsverbund Dermatologischer Kliniken, Institut an der Universität Göttingen, Universitätsmedizin Göttingen, Von-Bar-Str. 2-4, 37073, Göttingen, Deutschland. jgeier@gwdg.de.
authors.forename: J
authors.initials: J
authors.lastname: Geier
authors.affiliation: Institut für Medizininformatik, Biometrie und Epidemiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland.
authors.forename: W
authors.initials: W
authors.lastname: Uter
mesh_terms: D000485:Allergens / Q000276:immunology*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology*; D003937:Diagnosis, Differential; D006801:Humans; D010328:Patch Tests / Q000379:methods*; D010476:Perfume / Q000009:adverse effects*; D010936:Plant Extracts / Q000276:immunology*
chemical_list: D000485:Allergens; D010476:Perfume; D010936:Plant Extracts
keywords: Contact allergens; False-positive reactions; Fragrance mix; Individual substances; Patch tests