title: Effects of Short-Term Exercise Training With and Without Milk Intake on Cardiometabolic and Inflammatory Adaptations in Obese Adolescents.
abstract: There is some evidence that a combination of factors can reduce inflammation and associated metabolic risk factors. We studied the early cardiometabolic and inflammatory adaptations to a short-term exercise intervention with and without milk in obese adolescents. Fifty-four adolescents were randomized to consume milk post exercise (MILK) or a carbohydrate beverage (CONT) during one-week of daily exercise. Insulin levels were not different between the groups post training. Glucose was reduced over time in both groups (-9 ± 13 mg/ dl MILK and -6 ± 14 mg/dl CONT, p < .05) but not different between groups. There was a greater decrease in mean arterial pressure (MAP) in the MILK group (-3 ± 6 mmHg MILK vs. 2 ± 7 mmHg CONT, p < .04). Milk provided postexercise did not affect C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) or interleukin-6 (IL-6). The exercise intervention led to an increase in TNF-α in both groups (0.27 ± 0.7 pg/ml MILK and 0.48 ± 0.6 pg/ml CONT, p < .001). The early adaptations to a short-term exercise intervention in obese adolescents include a reduction in MAP and an increase in some inflammatory markers.
authors.affiliation: Dept. of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Maple
authors.initials: M
authors.lastname: Liu
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Gillis
authors.forename: Nicholas R
authors.initials: NR
authors.lastname: Persadie
authors.forename: Stephanie A
authors.initials: SA
authors.lastname: Atkinson
authors.forename: Stuart M
authors.initials: SM
authors.lastname: Phillips
authors.forename: Brian W
authors.initials: BW
authors.lastname: Timmons
mesh_terms: D000222:Adaptation, Physiological; D000293:Adolescent; D000818:Animals; D062186:Arterial Pressure; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D002097:C-Reactive Protein / Q000378:metabolism; D002648:Child; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D008892:Milk; D063766:Pediatric Obesity / Q000503:physiopathology*; D016037:Single-Blind Method; D013997:Time Factors; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D007328:Insulin; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein