title: Scientific basis of personalised tomographic radiation planning for radioembolisation: A form of brachytherapy planning.
abstract: Today's tomographic imaging techniques such as catheter-directed CT and single photon emission computed tomography with integrated computed tomography may be used for pre-therapy radiation planning for radioembolisation based on prospective calculation of tissue radiation absorbed doses. We outline the scientific concepts that underlie modern personalised tomographic radiation planning for radioembolisation and highlight its similarities to brachytherapy planning.
authors.affiliation: Department of Nuclear Medicine, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
authors.forename: Yung Hsiang
authors.initials: YH
authors.lastname: Kao
authors.affiliation: Department of Radiology, Department of Molecular Imaging and Therapy, University of Melbourne, Austin Health, Melbourne, Victoria, Australia.
authors.forename: Mark
authors.initials: M
authors.lastname: Goodwin
authors.affiliation: Department of Radiology, Department of Molecular Imaging and Therapy, University of Melbourne, Austin Health, Melbourne, Victoria, Australia.|Olivia Newton-John Cancer Research Institute, La Trobe University, Melbourne, Victoria, Australia.
authors.forename: Sze Ting
authors.initials: ST
authors.lastname: Lee
authors.affiliation: Department of Nuclear Medicine, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
authors.forename: Meir
authors.initials: M
authors.lastname: Lichtenstein
authors.affiliation: Department of Radiology, Department of Molecular Imaging and Therapy, University of Melbourne, Austin Health, Melbourne, Victoria, Australia.|Olivia Newton-John Cancer Research Institute, La Trobe University, Melbourne, Victoria, Australia.
authors.forename: Andrew Mark
authors.initials: AM
authors.lastname: Scott
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D015552:Injections, Intralesional / Q000379:methods; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D011868:Radioisotopes / Q000008:administration & dosage*; D019275:Radiopharmaceuticals / Q000008:administration & dosage; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D061089:Radiotherapy, Image-Guided / Q000379:methods*; D014054:Tomography
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals
keywords: SIR-Spheres; brachytherapy; dosimetry; radioembolisation; selective internal radiation therapy; yttrium-90