title: Incidence and distribution of paravascular lamellar holes and their relationship with macular retinoschisis in highly myopic eyes using spectral-domain oct.
abstract: The purpose of the study is to determine the incidence and distribution of paravascular lamellar holes (PLH) around retinal vessels in highly myopic eyes and their relationship with macular retinoschisis (MR). We examined 306 eyes of 178 patients with high myopia, performing multiple scans of the posterior pole within the retinal vascular arcades using spectral-domain OCT. Type of staphyloma was determined. PLH were divided into three groups: holes only (group 1), holes extending below vessels (group 2), and holes in an area of paravascular retinoschisis (group 3). OCT showed that 96/306 eyes (31.4 %) had PLH mainly along the infero-temporal arcade (39.9 %). Type V and IX staphylomas had a higher proportion of PLH in the infero-temporal arcade than other staphylomas. Group 3 eyes presented higher rates of myopia and staphyloma. MR was detected in 10/27 eyes (37 %) in Group 3, but only in 2/33 eyes (6.1 %) in Group 1. No MR was found in Group 2. PLH are relatively common in highly myopic eyes and mainly distributed in the inferior temporal arcade. Findings from this descriptive study suggest that distribution of PLH might be related to the type of staphyloma. Further studies are needed to evaluate the relevance of PLH in the pathogenesis of MR.
authors.affiliation: Department of Ophthalmology, Hospital de la Santa Creu i de Sant Pau, Universitat Autónoma de Barcelona (UAB), C/ Aragó 469 4º 5º 08013, Barcelona, Spain. 34128jvs@gmail.com.|Department of Ophthalmology, Institut Condal d´Oftalmología, Barcelona, Spain. 34128jvs@gmail.com.
authors.forename: José I
authors.initials: JI
authors.lastname: Vela
authors.affiliation: Department of Optometry, Hospital de la Santa Creu i de Sant Pau, Barcelona, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Sánchez
authors.affiliation: Department of Ophthalmology, Hospital de la Santa Creu i de Sant Pau, Universitat Autónoma de Barcelona (UAB), C/ Aragó 469 4º 5º 08013, Barcelona, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Díaz-Cascajosa
authors.affiliation: Department of Ophthalmology, Hospital de la Santa Creu i de Sant Pau, Universitat Autónoma de Barcelona (UAB), C/ Aragó 469 4º 5º 08013, Barcelona, Spain.
authors.forename: Ester
authors.initials: E
authors.lastname: Mingorance
authors.affiliation: Department of Ophthalmology, Institut Condal d´Oftalmología, Barcelona, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Andreu
authors.affiliation: Department of Ophthalmology, Hospital de la Santa Creu i de Sant Pau, Universitat Autónoma de Barcelona (UAB), C/ Aragó 469 4º 5º 08013, Barcelona, Spain.
authors.forename: José A
authors.initials: JA
authors.lastname: Buil
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications*; D011446:Prospective Studies; D012167:Retinal Perforations / Q000453:epidemiology* / Q000209:etiology; D041441:Retinoschisis / Q000150:complications*; D013030:Spain / Q000453:epidemiology; D041623:Tomography, Optical Coherence; D055815:Young Adult
keywords: Highly myopic eyes; Macular retinoschisis; Paravascular lamellar holes; Spectral-domain OCT