title: [CURRENT STATE OF COMBINED TREATMENT FOR LOCALLY ADVANCED GASTRIC CANCER. ACHIEVEMENTS AND FAILURES: BASIC TRENDS IN CLINICAL ONCOLOGY].
abstract: Despite the modern achievements of different methods of treatment, primarily surgical, with recognized need of standardization of lymphadenectomy D2, gastric cancer still remains one of the most difficult malignant tumors characterized by high rates of one-year mortality and low rates of survival that are far from satisfactory. According to experts such unsatisfactory results are determined by a combination of factors: the characteristics of ill people, their functional status, age characteristics, the prevalence of the disease at diagnosis with the presence of systemic micrometastases, resistance to treatment, etc. Moreover, a factor of resistance to treatment i.e. to existing schemes and methods is mostly a key one that determines low levels of long-term survival.
authors.forename: M D
authors.initials: MD
authors.lastname: Ter-Ovanesov
authors.forename: O E
authors.initials: OE
authors.lastname: Fatuev
authors.forename: A S
authors.initials: AS
authors.lastname: Gaboyan
authors.forename: A V
authors.initials: AV
authors.lastname: Levitsky
authors.forename: E E
authors.initials: EE
authors.lastname: Lesnidze
authors.forename: G A
authors.initials: GA
authors.lastname: Baksiyan
authors.forename: D L
authors.initials: DL
authors.lastname: Valkin
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002986:Clinical Trials as Topic; D019008:Drug Resistance, Neoplasm; D005743:Gastrectomy / Q000379:methods; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D020360:Neoadjuvant Therapy / Q000379:methods*; D011379:Prognosis; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000473:pathology* / Q000628:therapy*; D016019:Survival Analysis; D016896:Treatment Outcome