title: Post-irradiation Skin Changes Associated with Lumbosacral Radiculopathy.
abstract: We herein describe the cases of two patients with post-irradiation lumbosacral radiculopathy. The patients underwent postoperative radiation therapy to the abdomen due to testicular neoplasms 20 and 25 years prior to the onset of weakness, respectively. On physical examinations, asymmetric lower limb weakness and areflexia without apparent sensory loss were observed in both patients. Interestingly, artificial and squared atrophy of the skin and subcutaneous tissue, thought to correspond to the radiation fields, were observed in the lower back, and electromyography revealed selective motor axon loss localized to the lower extremities. The detection of skin changes in the area being irradiated is a valuable clue for diagnosing post-irradiation lumbosacral radiculopathy.
authors.affiliation: Department of Neurology, Dokkyo Medical University, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Iwasaki
authors.forename: Norito
authors.initials: N
authors.lastname: Kokubun
authors.forename: Takahito
authors.initials: T
authors.lastname: Nishihira
authors.forename: Takahide
authors.initials: T
authors.lastname: Nagashima
authors.forename: Koichi
authors.initials: K
authors.lastname: Hirata
mesh_terms: D000328:Adult; D004576:Electromyography; D006801:Humans; D008161:Lumbosacral Region; D008297:Male; D008875:Middle Aged; D010808:Physical Examination; D011832:Radiation Injuries; D011843:Radiculopathy / Q000209:etiology*