title: Desired Improvement Tool (DIT): A tool to assess desire for improvement in psoriasis patients.
abstract: No validated instrument exists to measure desire for improvement in psoriasis patients. To address this void, we conducted a single-center longitudinal study of 268 moderate-to-severe psoriasis patients to psychometrically validate the Desired Improvement Tool (DIT). The DIT is a single-item instrument scored 0-5 by the patient. A 0 indicates the patient is satisfied with disease level and does not desire further treatment. A 5 indicates a large amount of improvement is desired. The DIT demonstrated high test-retest reliability (Spearman, r = 0.97). Predictive and construct validity were moderate-to-high: r = 0.70 for BSA, 0.67 for PASI, and 0.56 for PGA and r = 0.67 for Life Quality Assessment (LQA), respectively. A sensitivity analysis revealed the DIT responded to changes in BSA. As a psychometrically valid tool, the DIT may guide clinical management of psoriasis patients by capturing an important clinical construct in an expedient and quantifiable manner.
authors.affiliation: a Department of Dermatology , Baylor University Medical Center , Dallas , TX , USA .
authors.forename: Daniel
authors.initials: D
authors.lastname: Zaghi
authors.affiliation: b Department of Biomedical Informatics , University of Utah School of Medicine , Salt Lake City , UT , USA .
authors.forename: Charlene
authors.initials: C
authors.lastname: Weir
authors.affiliation: c Department of Internal Medicine , University of Utah School of Medicine , Salt Lake City , UT , USA .
authors.forename: Jian
authors.initials: J
authors.lastname: Ying
authors.affiliation: d West Dermatology, 1300 Avenida Vista Hermosa , San Clemente , CA , USA , and.
authors.forename: Christopher
authors.initials: C
authors.lastname: Carlin
authors.affiliation: c Department of Internal Medicine , University of Utah School of Medicine , Salt Lake City , UT , USA .
authors.forename: Tom
authors.initials: T
authors.lastname: Greene
authors.affiliation: e Department of Dermatology , University of Utah School of Medicine , Salt Lake City , UT , USA.
authors.forename: Rosemary
authors.initials: R
authors.lastname: DeShazo
authors.affiliation: e Department of Dermatology , University of Utah School of Medicine , Salt Lake City , UT , USA.
authors.forename: Kristina
authors.initials: K
authors.lastname: Callis Duffin
authors.affiliation: e Department of Dermatology , University of Utah School of Medicine , Salt Lake City , UT , USA.
authors.forename: Gerald G
authors.initials: GG
authors.lastname: Krueger
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy / Q000523:psychology*; D011594:Psychometrics; D015203:Reproducibility of Results; D012720:Severity of Illness Index
keywords: Desired improvement; patient reported outcome; psoriasis