title: Pentafecta Outcomes of 230 Cases of Robotic-assisted Radical Prostatectomy with Bilateral Neurovascular Bundle Preservation.
abstract: OBJECTIVE
  We analyzed pentafecta outcomes [complication-free, continence, potency, negative surgical margins (NSM)], biochemical recurrence (BCR)-free] of 230 patients undergoing robotic-assisted radical prostatectomy (RARP) with bilateral neurovascular (NVB) preservation.
  
  
  METHODS
  Patient outcomes (group I, cases 1-115; group II, cases 116-230) were assessed prospectively. Definitions were: continence, using no pads; potency, ability to achieve/maintain erections firm enough for sexual intercourse; positive surgical margin, presence of tumor tissue on inked specimen surface; and BCR, two consecutive PSA levels >0.2 ng/ml after RALP.
  
  
  RESULTS
  The mean patient age was 62.5 years, mean PSA=8.62 ng/ml. The complication-free rate was 93.9% (216/230), continence rate 98.3% (226/230), potency 86.1% (198/230), NSM 77.0% (177/230) and BCR-free 92.6% (213/230). The trifecta rate (continence, potency, BCR-free) was 81.7% (188/230). The pentafecta rate was 60.4% (139/230).
  
  
  CONCLUSIONS
  Pentafecta is the new standard of outcomes for RARP with bilateral NVB, with patient selection and reduced positive surgical margins attaining best outcomes.
authors.affiliation: Division of Urology, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C. Division of Urology, Department of Surgery, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan, R.O.C. School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C. ycou228@gmail.com.
authors.forename: Yen-Chuan
authors.initials: YC
authors.lastname: Ou
authors.affiliation: Division of Urology, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C. School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C.
authors.forename: Chun-Kuang
authors.initials: CK
authors.lastname: Yang
authors.affiliation: Department of Anesthesiology, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C. School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C.
authors.forename: Hsun-Ming
authors.initials: HM
authors.lastname: Kang
authors.affiliation: Department of Research, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C. School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C.
authors.forename: Kuangh-Si
authors.initials: KS
authors.lastname: Chang
authors.affiliation: Department of Pathology, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C. School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C.
authors.forename: John
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Radiation, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C. School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C.
authors.forename: Siu-Wan
authors.initials: SW
authors.lastname: Hung
authors.affiliation: Division of Urology, Department of Surgery, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan, R.O.C. School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C.
authors.forename: Min-Che
authors.initials: MC
authors.lastname: Tung
authors.affiliation: School of Medicine, National Yang-Ming University, Taipei, Taiwan, R.O.C.
authors.forename: Ashutosh K
authors.initials: AK
authors.lastname: Tewari
authors.affiliation: Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, U.S.A.
authors.forename: Vipul R
authors.initials: VR
authors.lastname: Patel
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D059351:Organ Sparing Treatments; D017430:Prostate-Specific Antigen / Q000378:metabolism; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000601:surgery*; D012371:Robotics; D016896:Treatment Outcome
chemical_list: D017430:Prostate-Specific Antigen
keywords: Biochemical recurrence; laparoscopy; pentafecta; prostate cancer; radical prostatectomy; robotics