title: Serological survey of antibodies to Toxoplasma gondii and Coxiella burnetii in rodents in north-western African islands (Canary Islands and Cape Verde).
abstract: Coxiella burnetii and Toxoplasma gondii are intracellular parasites that cause important reproductive disorders in animals and humans worldwide, resulting in high economic losses. The aim of the present study was to analyse the possible role of peridomestic small mammals in the maintenance and transmission of C. burnetii and T. gondii in the north-western African archipelagos of the Canary Islands and Cape Verde, where these species are commonly found affecting humans and farm animals. Between 2009 and 2013, 108 black rats (Rattus rattus) and 77 mice (Mus musculus) were analysed for the presence of Coxiella and Toxoplasma antibodies by enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence (IFA), respectively. Our results showed a wide distribution of C. burnetii and T. gondii, except for T. gondii in Cape Verde, in both rodent species. The overall seroprevalence of C. burnetii antibodies was 12.4%; 21.1% for Cape Verde and 10.2% for the Canary Islands. With respect to T. gondii, seropositive rodents were only observed in the Canary Islands, with an overall seroprevalence of 15%. Considering the fact that both pathogens can infect a large range of hosts, including livestock and humans, the results are of public health and veterinary importance and could be used by governmental entities to manage risk factors and to prevent future cases of Q fever and toxoplasmosis.
authors.affiliation: University Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna. pforonda@ull.edu.es.
authors.forename: Pilar
authors.initials: P
authors.lastname: Foronda
authors.forename: Josué
authors.initials: J
authors.lastname: Plata-Luis
authors.forename: Borja
authors.initials: B
authors.lastname: del Castillo-Figueruelo
authors.forename: Ángela
authors.initials: Á
authors.lastname: Fernández-Álvarez
authors.forename: Aarón
authors.initials: A
authors.lastname: Martín-Alonso
authors.forename: Carlos
authors.initials: C
authors.lastname: Feliu
authors.forename: Marilena D
authors.initials: MD
authors.lastname: Cabral
authors.forename: Basilio
authors.initials: B
authors.lastname: Valladares
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial; D000913:Antibodies, Protozoan; D055726:Cabo Verde / Q000453:epidemiology; D016997:Coxiella burnetii / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay; D019084:Fluorescent Antibody Technique, Indirect; D051379:Mice; D015995:Prevalence; D011778:Q Fever / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D051381:Rats; D012376:Rodent Diseases / Q000453:epidemiology* / Q000382:microbiology / Q000469:parasitology; D016036:Seroepidemiologic Studies; D013030:Spain / Q000453:epidemiology; D014122:Toxoplasma / Q000302:isolation & purification*; D014124:Toxoplasmosis, Animal / Q000453:epidemiology* / Q000469:parasitology
chemical_list: D000907:Antibodies, Bacterial; D000913:Antibodies, Protozoan