title: Morbidity and mortality of black HIV-positive patients with end-stage kidney disease receiving chronic haemodialysis in South Africa.
abstract: BACKGROUND
  There are few published data from South Africa (SA) on the outcomes of black HIV-positive patients receiving chronic haemodialysis.
  
  
  METHODS
  This retrospective study compared the incidences of vascular and infectious morbidity and mortality in black HIV-positive patients with those in a group of HIV-negative patients matched for ethnicity, age and gender. All the patients were receiving chronic haemodialysis in the medically insured healthcare sector of SA.
  
  
  RESULTS
  The incidence of tuberculosis and hospital admission rates for vascular access-related infections were significantly higher in the HIV-positive group than the HIV-negative group. The HIV-positive group had significantly lower albumin (p&lt;0.05) and haemoglobin levels (p&lt;0.01), but this did not impact on mortality. Survival in both groups was excellent. In the HIV-positive group, viral suppression rates were suboptimal with &lt;50% of patients on antiretroviral therapy completely virally suppressed.
  
  
  CONCLUSIONS
  This study has shown that black HIV-positive patients receiving chronic haemodialysis in a healthcare-funded environment in SA have excellent overall survival in spite of higher hospital admission rates and higher infectious morbidity compared with HIV-negative patients.
authors.affiliation: Wits Donald Gordon Medical Centre, Parktown, Johannesburg, South Africa; Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. june.fabian@mweb.co.za.
authors.forename: June
authors.initials: J
authors.lastname: Fabian
authors.forename: Heather Anne
authors.initials: HA
authors.lastname: Maher
authors.forename: Chevon
authors.initials: C
authors.lastname: Clark
authors.forename: Saraladevi
authors.initials: S
authors.lastname: Naicker
authors.forename: Piet
authors.initials: P
authors.lastname: Becker
authors.forename: Willem Daniel Francois
authors.initials: WD
authors.lastname: Venter
mesh_terms: D000328:Adult; D044383:Black People; D005260:Female; D005500:Follow-Up Studies; D006679:HIV Seropositivity / Q000150:complications / Q000208:ethnology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000208:ethnology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D006435:Renal Dialysis; D012189:Retrospective Studies; D013019:South Africa / Q000453:epidemiology; D015996:Survival Rate / Q000639:trends