title: Bioresorbable vascular scaffold implantation for the treatment of coronary in-stent restenosis: results from a multicenter Italian experience.
abstract: This multicenter experience sought to investigate the feasibility and safety of BVS for the treatment of ISR. From April 2012 to June 2014, a total of 315 patients (334 lesions) underwent PCI for ISR at the participating centers. Of those, 83 patients (90 lesions) received BVS. Procedural success was achieved in all patients. At a median of 7 (IQR 3-18) months follow-up, MACCE rate was 12%, TLR 7.7%, while one (1.1%) definite BVS-in-stent thrombosis was reported. The results of this multicenter experience suggest that BVS implantation for the treatment of coronary ISR is technically feasible and associated with favorable mid-term clinical results. These data could be considered hypothesis generating for a future randomized clinical trial.
authors.affiliation: Laboratory of Invasive Cardiology, Department of Cardiology, Presidio Ospedaliero "Monaldi", Azienda Ospedaliera Dei Colli, Napoli, Italy; Laboratory of Invasive Cardiology, Department of Cardiology, Second University of Naples, Presidio Ospedaliero "Monaldi", Azienda Ospedaliera Dei Colli, Napoli, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Moscarella
authors.affiliation: Laboratory of Invasive Cardiology, Department of Cardiology, Presidio Ospedaliero "Monaldi", Azienda Ospedaliera Dei Colli, Napoli, Italy.
authors.forename: Attilio
authors.initials: A
authors.lastname: Varricchio
authors.affiliation: Laboratory of Invasive Cardiology, Dipartimento di Scienze Biomediche Avanzate, Università degli Studi "Federico II", Napoli, Italy. Electronic address: geko50@hotmail.com.
authors.forename: Eugenio
authors.initials: E
authors.lastname: Stabile
authors.affiliation: U.O. Emodinamica e Cardiologia Interventistica EMO-GVM Centro Cuore Columbus ed Ospedale San Raffaele, Milano; Italy.
authors.forename: Azeem
authors.initials: A
authors.lastname: Latib
authors.affiliation: U.O.C. Cardiologia, Azienda Ospedaliera Bolognini Seriate, Bergamo, Italy.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Ielasi
authors.affiliation: U.O.C. Cardiologia, Azienda Ospedaliera Bolognini Seriate, Bergamo, Italy.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Tespili
authors.affiliation: Laboratory of Invasive Cardiology, Azienda Ospedaliera Fatebenefratelli, Milano, Italy.
authors.forename: Bernardo
authors.initials: B
authors.lastname: Cortese
authors.affiliation: Laboratory of Invasive Cardiology, Department of Cardiology, Second University of Naples, Presidio Ospedaliero "Monaldi", Azienda Ospedaliera Dei Colli, Napoli, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Calabrò
authors.affiliation: Laboratory of Invasive Cardiology, Department of Cardiology, Presidio Ospedaliero "Monaldi", Azienda Ospedaliera Dei Colli, Napoli, Italy; Laboratory of Invasive Cardiology, Department of Cardiology, Second University of Naples, Presidio Ospedaliero "Monaldi", Azienda Ospedaliera Dei Colli, Napoli, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Granata
authors.affiliation: U.O. Emodinamica e Cardiologia Interventistica EMO-GVM Centro Cuore Columbus ed Ospedale San Raffaele, Milano; Italy.
authors.forename: Vasileios F
authors.initials: VF
authors.lastname: Panoulas
authors.affiliation: Laboratory of Invasive Cardiology, Dipartimento di Scienze Biomediche Avanzate, Università degli Studi "Federico II", Napoli, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Franzone
authors.affiliation: Laboratory of Invasive Cardiology, Dipartimento di Scienze Biomediche Avanzate, Università degli Studi "Federico II", Napoli, Italy.
authors.forename: Bruno
authors.initials: B
authors.lastname: Trimarco
authors.affiliation: Laboratory of Invasive Cardiology, Department of Cardiology, Presidio Ospedaliero "Monaldi", Azienda Ospedaliera Dei Colli, Napoli, Italy.
authors.forename: Giulio
authors.initials: G
authors.lastname: Bonzani
authors.affiliation: Laboratory of Invasive Cardiology, Dipartimento di Scienze Biomediche Avanzate, Università degli Studi "Federico II", Napoli, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Esposito
authors.affiliation: U.O. Emodinamica e Cardiologia Interventistica EMO-GVM Centro Cuore Columbus ed Ospedale San Raffaele, Milano; Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Colombo
mesh_terms: D020341:Absorbable Implants; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D015331:Cohort Studies; D017023:Coronary Angiography / Q000379:methods; D023903:Coronary Restenosis / Q000601:surgery / Q000628:therapy*; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000379:methods; D011446:Prospective Studies; D015607:Stents; D016896:Treatment Outcome
keywords: BVS; DES; Restenosis; Stent