title: Positive relationship detected between soil bioaccessible organic pollutants and antibiotic resistance genes at dairy farms in Nanjing, Eastern China.
abstract: Co-contaminated soils by organic pollutants (OPs), antibiotics and antibiotic resistance genes (ARGs) have been becoming an emerging problem. However, it is unclear if an interaction exists between mixed pollutants and ARG abundance. Therefore, the potential relationship between OP contents and ARG and class 1 integron-integrase gene (intI1) abundance was investigated from seven dairy farms in Nanjing, Eastern China. Phenanthrene, pentachlorophenol, sulfadiazine, roxithromycin, associated ARG genes, and intI1 had the highest detection frequencies. Correlation analysis suggested a stronger positive relationship between the ARG abundance and the bioaccessible OP content than the total OP content. Additionally, the significant correlation between the bioaccessible mixed pollutant contents and ARG/intI1 abundance suggested a direct/indirect impact of the bioaccessible mixed pollutants on soil ARG dissemination. This study provided a preliminary understanding of the interaction between mixed pollutants and ARGs in co-contaminated soils.
authors.affiliation: Soil Ecology Lab, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, PR China; Key Laboratory of Soil Environment and Pollution Remediation, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China.
authors.forename: Mingming
authors.initials: M
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, PR China. Electronic address: yemao@issas.ac.cn.
authors.forename: Mao
authors.initials: M
authors.lastname: Ye
authors.affiliation: Soil Ecology Lab, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address: wujun2013@njau.edu.cn.
authors.forename: Jun
authors.initials: J
authors.lastname: Wu
authors.affiliation: Institute of Agricultural Resources and Environment, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
authors.forename: Yanfang
authors.initials: Y
authors.lastname: Feng
authors.affiliation: Nanjing Institute of Environmental Science, Ministry of Environmental Protection of China, Nanjing, 210042, China.
authors.forename: Jinzhong
authors.initials: J
authors.lastname: Wan
authors.affiliation: Soil Ecology Lab, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, PR China.
authors.forename: Da
authors.initials: D
authors.lastname: Tian
authors.affiliation: Soil Ecology Lab, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, PR China.
authors.forename: Fangyuan
authors.initials: F
authors.lastname: Shen
authors.affiliation: Soil Ecology Lab, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, PR China.
authors.forename: Kuan
authors.initials: K
authors.lastname: Liu
authors.affiliation: Soil Ecology Lab, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, PR China.
authors.forename: Feng
authors.initials: F
authors.lastname: Hu
authors.affiliation: Soil Ecology Lab, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, PR China.
authors.forename: Huixin
authors.initials: H
authors.lastname: Li
authors.affiliation: State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, PR China.
authors.forename: Xin
authors.initials: X
authors.lastname: Jiang
authors.affiliation: Institute of Agricultural Resources and Environment, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
authors.forename: Linzhang
authors.initials: L
authors.lastname: Yang
authors.affiliation: Department of Chemistry, Maseno University, Private Bag Maseno 40105, Kenya.
authors.forename: Fredrick Orori
authors.initials: FO
authors.lastname: Kengara
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D002681:China; D003612:Dairying; D024881:Drug Resistance, Bacterial; D005798:Genes, Bacterial / Q000187:drug effects; D032023:Integrons / Q000187:drug effects; D012987:Soil / Q000737:chemistry; D012988:Soil Microbiology; D012989:Soil Pollutants / Q000032:analysis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D012987:Soil; D012989:Soil Pollutants
keywords: Antibiotic resistance genes; Bioaccessible pollutants; Class 1 integron; Correlation