title: The association between orthostatic increase in pulse pressure and ischemic heart disease.
abstract: The clinical meaning of changes in PP with posture remains unclear. We performed treadmill exercise testing on 144 subjects to diagnose ischemic heart disease, and measured the PPs in the supine and standing positions. The differences in the two PPs ranged between -35 and 45 mmHg. Eleven subjects were diagnosed with significant coronary ischemia. The differences in the PPs were significantly increased, and PP in the standing position was significantly elevated in these subjects. A large difference in the PPs in the standing and supine positions was associated with significant coronary ischemia, independent of significant covariables.
authors.affiliation: Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo , Tokyo , Japan .
authors.forename: Munenori
authors.initials: M
authors.lastname: Takata
authors.forename: Eisuke
authors.initials: E
authors.lastname: Amiya
authors.forename: Masafumi
authors.initials: M
authors.lastname: Watanabe
authors.forename: Namie
authors.initials: N
authors.lastname: Yamada
authors.forename: Aya
authors.initials: A
authors.lastname: Watanabe
authors.forename: Shuichi
authors.initials: S
authors.lastname: Kawarasaki
authors.forename: Atsuko
authors.initials: A
authors.lastname: Ozeki
authors.forename: Tomoko
authors.initials: T
authors.lastname: Nakao
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Hosoya
authors.forename: Jiro
authors.initials: J
authors.lastname: Ando
authors.forename: Issei
authors.initials: I
authors.lastname: Komuro
keywords: Ischemic heart disease; orthostatic change; pulse pressure