title: Primary Spinal Glioblastoma Multiforme with Secondary Manifestation as a Cerebral "Angioglioma." Literature Review and Case Report.
abstract: Primary intramedullary spinal glioblastoma multiforme (sGBM) with a secondary cerebral manifestation is a very rare entity with a poor outcome. Case studies show a mean average of survival of 10 months after diagnosis. These tumors tend to develop at a young age. A combination with an arteriovenous malformation in the same location has never been published before. Vascular malformations in association with cerebral glioblastomas have only been reported in five cases so far. Proangiogenic factors are assumed to be involved in the appearance of both entities. We present a case study and a review of the literature.
authors.affiliation: Department of Neurosurgery, Julius-Maximilians-University, Würzburg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Linsenmann
authors.affiliation: Department of Neurosurgery, Julius-Maximilians-University, Würzburg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Westermaier
authors.affiliation: Department of Neurosurgery, General Hospital of Klagenfurt, Austria.
authors.forename: Giles Hamilton
authors.initials: GH
authors.lastname: Vince
authors.affiliation: Department of Neuropathology, Julius-Maximilians-University, Würzburg, Germany.
authors.forename: Camelia Maria
authors.initials: CM
authors.lastname: Monoranu
authors.affiliation: Department of Neurosurgery, Julius-Maximilians-University, Würzburg, Germany.
authors.forename: Mario
authors.initials: M
authors.lastname: Löhr
authors.affiliation: Department of Neurosurgery, Julius-Maximilians-University, Würzburg, Germany.
authors.forename: Ralf-Ingo
authors.initials: RI
authors.lastname: Ernestus
authors.affiliation: Department of Neurosurgery, Julius-Maximilians-University, Würzburg, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Stetter
keywords: arteriovenous malformation; cerebral angioglioma; spinal glioblastoma