title: Salvage Conservation Laryngeal Surgery After Radiation Therapy Failure.
abstract: Conservation laryngeal surgery (CLS) includes time-honored approaches such as the vertical partial laryngectomy and the open horizontal supraglottic laryngectomy, as well as the supracricoid partial laryngectomy and transoral laser microsurgery. Carefully selected patients can undergo transoral endoscopic or open CLS for early to intermediate stage recurrent tumors of the glottic and supraglottic larynx. Patient factors, such as comorbid pulmonary disease, are essential in selecting patients for CLS, especially after previous radiation therapy. This article reviews the preoperative indications and postoperative management of salvage CLS after radiation therapy for laryngeal cancer.
authors.affiliation: Division of Head and Neck Surgery, Department of Otolaryngology - Head and Neck Surgery, Stanford University, 801 Welch Road, Palo Alto, CA 94305-5820, USA.
authors.forename: Michelle Mizhi
authors.initials: MM
authors.lastname: Chen
authors.affiliation: Head and Neck Oncology Program, Division of Head and Neck Surgery, Department of Otolaryngology - Head and Neck Surgery, Stanford University, 875 Blake Wilbur Drive, Palo Alto, CA 94305-5820, USA. Electronic address: holsinger@stanford.edu.
authors.forename: F Christopher
authors.initials: FC
authors.lastname: Holsinger
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, University Paris Descartes Sorbonne Paris Cité, Hôpital Européen Georges Pompidou, Assistance Publique - Hôpitaux de Paris, 20 rue Leblanc, Paris 70015, France.
authors.forename: Ollivier
authors.initials: O
authors.lastname: Laccourreye
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D005931:Glottis / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D007825:Laryngectomy / Q000379:methods; D053685:Laser Therapy / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D059351:Organ Sparing Treatments / Q000379:methods; D018579:Patient Selection; D016879:Salvage Therapy / Q000379:methods*; D017211:Treatment Failure
keywords: Conservation laryngeal surgery; Larynx; Laser; Radiation; Salvage; Supracricoid