title: Factors associated with adherence to oral antihyperglycemic monotherapy in patients with type 2 diabetes mellitus in the United Kingdom.
abstract: To evaluate adherence to oral antihyperglycemic monotherapy, we conducted a retrospective cohort study of a UK clinical database. The mean proportion of days covered was 73.5%, and 60.1% of patients were adherent. Younger age and fewer concomitant medications were negatively associated with the likelihood of being adherent.
authors.affiliation: Merck & Co., Inc., Kenilworth, NJ, USA. Electronic address: kaan_tunceli@merck.com.
authors.forename: Kaan
authors.initials: K
authors.lastname: Tunceli
authors.affiliation: Merck & Co., Inc., Kenilworth, NJ, USA.
authors.forename: Kristy
authors.initials: K
authors.lastname: Iglay
authors.affiliation: Merck & Co., Inc., Kenilworth, NJ, USA.
authors.forename: Changgeng
authors.initials: C
authors.lastname: Zhao
authors.affiliation: Merck & Co., Inc., Kenilworth, NJ, USA.
authors.forename: Kimberly G
authors.initials: KG
authors.lastname: Brodovicz
authors.affiliation: Merck & Co., Inc., Kenilworth, NJ, USA.
authors.forename: Larry
authors.initials: L
authors.lastname: Radican
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D016208:Databases, Factual; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012959:Socioeconomic Factors; D006113:United Kingdom / Q000453:epidemiology; D016903:Drug Monitoring
chemical_list: D007004:Hypoglycemic Agents
keywords: Adherence; Drug therapy; Logistic regression analysis; Observational study; Oral antihyperglycemic agents; Type 2 diabetes mellitus