title: Comparison of MR imaging features of solid pseudopapillary neoplasm of pancreas between male and female patients.
abstract: OBJECTIVE
  To evaluate MR imaging features of solid pseudopapillary neoplasms (SPN) in male patients and to compare them with the MR imaging features in female patients.
  
  
  METHODS
  Fifty patients who were histologically confirmed as SPN (M:F=8:42, mean age=36.4 years) with preoperative MRI were included. The following imaging features were reviewed: size, location, shape, margin, encapsulation, solid-cystic ratio, pancreatic duct dilatation, parenchymal atrophy, T1 signal intensity, T2 signal intensity, and morphological and dynamic pattern of enhancement. The statistical differences between male and female patients were analyzed.
  
  
  RESULTS
  The average age of male patients (50.8 ± 4.1 years) was significantly higher (p<0.01) than female patients (33.7 ± 2.0 years). The shape of SPN in male patients was predominantly lobulated (n=6/8, 75.0%) compared to female patients, in whom oval shaped SPN was most prevalent (n=26/42, 61.91%) (P=0.02). SPN in male patients contained less cystic component (solid, n=4/8, 50.0%; mainly solid, n=4/8, 50.0%) while cystic (n=5/42, 11.90%) or mainly cystic (n=13/42, 30.95%) lesions were significantly more prevalent in female patients (P=0.03). The majority of SPNs in both groups showed progressive heterogeneous enhancement pattern. Other MR imaging features showed no significant differences between the male and female patients.
  
  
  CONCLUSIONS
  On MRI, SPN in male patients appeared as mainly solid mass with a lobulating contour and heterogeneous progressive enhancement occurring at an older age than female patients. Recognition of imaging features of SPN in male patients compared to typical SPN in female patients should assist in correct differentiation of SPN from other pancreatic tumors.
authors.affiliation: Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Young Keun
authors.initials: YK
authors.lastname: Sur
authors.affiliation: Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea. Electronic address: radljh@ajou.ac.kr.
authors.forename: Jei Hee
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Jai Keun
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Min Jung
authors.initials: MJ
authors.lastname: Park
authors.affiliation: Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea.
authors.forename: Bohyun
authors.initials: B
authors.lastname: Kim
authors.affiliation: Department of Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Mi-Suk
authors.initials: MS
authors.lastname: Park
authors.affiliation: Department of Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Jin-Young
authors.initials: JY
authors.lastname: Choi
authors.affiliation: Department of Pathology, Ajou University School of Medicine, Republic of Korea.
authors.forename: Young Bae
authors.initials: YB
authors.lastname: Kim
authors.affiliation: Department of Pathology, Ajou University School of Medicine, Republic of Korea.
authors.forename: Dakeun
authors.initials: D
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001284:Atrophy / Q000473:pathology; D002291:Carcinoma, Papillary / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010179:Pancreas / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000473:pathology*; D012189:Retrospective Studies; D012737:Sex Factors; D055815:Young Adult
keywords: Pancreas MRI; Pancreatic mass; Solid pseudopapillary neoplasm