title: Sleep Duration and Blood Glucose Control in Women With Gestational Diabetes Mellitus.
abstract: OBJECTIVE
  To describe the relationship between objectively assessed sleep and blood glucose in a prospective cohort of women recently diagnosed with gestational diabetes mellitus (GDM).
  
  
  METHODS
  Women with GDM were enrolled immediately after attending a GDM education class. All patients were recruited during their first week of attempted dietary management of GDM. They were instructed on the use of a glucometer and on the principles of a GDM diet. Women wore an actigraph and completed a sleep log for 7 consecutive days. Glucose records were compared against the objective sleep data. Linear mixed model analysis was used to estimate the association of sleep duration on morning fasting and 1-hour postprandial blood glucose concentrations.
  
  
  RESULTS
  Thirty-seven participants provided data for 213 sleep intervals that corresponded to at least one glucose reading. Sleep duration was negatively associated with fasting and 1-hour postprandial blood glucose concentrations In analyses adjusted for age, gestational age, and body mass index, a 1-hour increase in sleep time was associated with statistically significant reductions in fasting glucose (-2.09 mg/dL, 95% confidence interval [CI] -3.98 to -0.20) as well as postprandial glucose concentrations (lunch -4.62 mg/dL, 95% CI -8.75 to -0.50; dinner -6.07 mg/dL, 95% CI -9.40 to -2.73).
  
  
  CONCLUSIONS
  Short sleep durations are associated with worsened glucose control in women with gestational diabetes. Educating women on healthy sleep and screening for and treating sleep disorders during pregnancy may have a role in optimizing blood glucose control in gestational diabetes.
  
  
  METHODS
  II.
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital, and Magee-Women's Research Institute, Pittsburgh, Pennsylvania; and the Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina.
authors.forename: Roxanna
authors.initials: R
authors.lastname: Twedt
authors.forename: Megan
authors.initials: M
authors.lastname: Bradley
authors.forename: Danielle
authors.initials: D
authors.lastname: Deiseroth
authors.forename: Andrew
authors.initials: A
authors.lastname: Althouse
authors.forename: Francesca
authors.initials: F
authors.lastname: Facco
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D015190:Blood Glucose Self-Monitoring / Q000379:methods / Q000523:psychology / Q000592:standards; D015992:Body Mass Index; D015331:Cohort Studies; D016001:Confidence Intervals; D016640:Diabetes, Gestational / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D020920:Dyssomnias / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D008423:Maternal Age; D008875:Middle Aged; D019518:Postprandial Period; D011247:Pregnancy; D064186:Prenatal Education / Q000379:methods; D011446:Prospective Studies; D012890:Sleep; D014481:United States
chemical_list: D001786:Blood Glucose