title: When there will never be a randomized controlled trial.
abstract: There are many unanswered questions about how to manage secondary hyperparathyroidism and associated alterations in mineral metabolism in patients with end-stage renal disease. We provide commentary on an observational study by Komaba et al. that presents interesting new insights into the long-standing controversy related to the impact of parathyroidectomy on survival of hemodialysis patients.
authors.affiliation: 1] Division of Nephrology, Duke University School of Medicine, Durham, North Carolina, USA [2] Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
authors.forename: Julia J
authors.initials: JJ
authors.lastname: Scialla
authors.affiliation: 1] Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA [2] Center for Translational Metabolism and Health, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
authors.forename: Myles
authors.initials: M
authors.lastname: Wolf
mesh_terms: D002318:Cardiovascular Diseases / Q000401:mortality*; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000601:surgery*; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D016105:Parathyroidectomy