title: Multicentric evaluation of eight glucose and four ketone blood meters.
abstract: OBJECTIVE
  High precision meters for blood glycemia are mandatory for monitoring glucose status in patients, avoiding both hypo- and hyper-glycemia. Health care providers routinely used in both out- and in-patients point-of-care measurements of glucose and ketone. These measurements, frequently used for medical decisions, are known to be less accurate than those performed in laboratories. Our aim was to evaluate, within the frame of an Assistance Publique-Hôpitaux de Paris (AP-HP) multicentric study, the performances of eight glucose and four ketone meters, either connected or non-connected to a laboratory software.
  
  
  METHODS
  Glucose meter accuracy, precision, correlation with plasma glucose determined in central laboratories and hematocrit interferences were determined according to the ISO 15197:2003 norm. The same norm was applied for the determination of accuracy, precision and recovery of ketone meters for B-hydroxybutyrate measurements.
  
  
  CONCLUSIONS
  Among those meters, seven were considered as acceptable for glucose measurement and two for ketone measurement. Since all meters do not fit clinically relevant criteria, meters' performances have to be evaluated before use in clinical practice.
authors.affiliation: AP-HP Hôpital Beaujon, Service de Biochimie clinique, Clichy F-92118, France.
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Guimont
authors.affiliation: AP-HP Hôpital Bichat, Service de Biochimie Paris, F-75018, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Desjobert
authors.affiliation: AP-HP, Hôpital La Pitié-Salpêtrière, Service de Biochimie, Paris F-75013, France.
authors.forename: Michèle
authors.initials: M
authors.lastname: Fonfrède
authors.affiliation: AP-HP, Hôpital Saint Louis, Service de Biochimie et de Biologie Moléculaire, Paris F-75010, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Vitoux
authors.affiliation: APHP, Hôpital Robert Debré Service de Biochimie, Paris F-75019, France.
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Benoist
authors.affiliation: APHP, Hôpital Lariboisière, Service de Biochimie et de Biologie Moléculaire, Paris F-75010, France.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Launay
authors.affiliation: AP-HP Hôpital Beaujon, Service de Biochimie clinique, Clichy F-92118, France; APHP, Hôpital Lariboisière, Service de Biochimie et de Biologie Moléculaire, Paris F-75010, France. Electronic address: katell.peoch@bjn.aphp.fr.
authors.forename: Katell
authors.initials: K
authors.lastname: Peoc'h
authors.affiliation: APHP, Hôpital Tenon, Service de Biochimie et Hormonologie, Paris F-75020, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Lefèvre
mesh_terms: D000328:Adult; D057205:Automation, Laboratory / Q000592:standards*; D001786:Blood Glucose / Q000032:analysis*; D003920:Diabetes Mellitus / Q000097:blood* / Q000175:diagnosis; D017408:Guidelines as Topic; D006400:Hematocrit; D006801:Humans; D006885:Hydroxybutyrates / Q000097:blood; D006943:Hyperglycemia / Q000097:blood* / Q000175:diagnosis; D007659:Ketones / Q000097:blood*; D019095:Point-of-Care Systems / Q000592:standards; D011446:Prospective Studies; D012984:Software
chemical_list: D001786:Blood Glucose; D006885:Hydroxybutyrates; D007659:Ketones
keywords: Diabetes; Glucose meter; Glycemia; ISO 15197 norm; Ketone meter; Point-of-care