title: Invasive Fungal Infections in Pediatric Acute Myelogenous Leukemia.
abstract: This study investigates invasive fungal infections (IFIs) in patients with acute myelogenous leukemia who were included in the Enfant Leucemie Aigue 02 protocol between 2005 and 2011. Among 387 patients, 15 had aspergillosis, 9 had candidiasis, and 2 had mucormycosis. The most frequent localization of IFIs was in the lungs. It was found that after a median of 34 months, 2 deaths were attributable to IFI without any difference in survival between the groups with and without IFI.
authors.affiliation: From the *Unité d'Oncologie Hématologie Pédiatrique, Hôpital des Enfants, Groupe Hospitalier, Pellegrin, CHU de Bordeaux, Bordeaux Cedex, France; †Service d'Onco-Hématologie Pédiatrique, Hôpital Armand-Trousseau, Paris Cedex, France; ‡Institut d'Hématologie Oncologie Pédiatrique, CHU Lyon, Lyon Cedex, France; and §Unité d'Hémato-Oncologie Pédiatrique, CHU Hôpital Sud, Rennes Cedex, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Ducassou
authors.forename: Delphine
authors.initials: D
authors.lastname: Rivaud
authors.forename: Anne
authors.initials: A
authors.lastname: Auvrignon
authors.forename: Cécile
authors.initials: C
authors.lastname: Vérité
authors.forename: Yves
authors.initials: Y
authors.lastname: Bertrand
authors.forename: Virginie
authors.initials: V
authors.lastname: Gandemer
authors.forename: Guy
authors.initials: G
authors.lastname: Leverger
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000453:epidemiology*; D008297:Male; D009181:Mycoses / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology*; D012189:Retrospective Studies; D017211:Treatment Failure
chemical_list: D000935:Antifungal Agents