title: Palmoplantar pustular psoriasis induced by adalimumab: a case report and literature review.
abstract: TNF-α inhibitors (anti-TNF-α) are agents increasingly used in the treatment of rheumatic diseases resistant to classical disease-modifying treatment and they provide significant improvement of disease activity. However, these agents have many cutaneous side effects including psoriasis. Numerous reports of the induction or worsening of psoriasis in patients treated with TNF antagonists indicate that this is not a rare phenomenon. In this study, we present a patient with ankylosing spondylitis who developed palmoplantar pustular psoriasis after receiving anti-TNF-α therapy for 4 months.
authors.affiliation: Physical Therapy & Rehabilitation Department, Kayseri Education & Research Hospital, Atatürk Avenue, No:78, 38010 Kayseri, Turkey.
authors.forename: Nurdan
authors.initials: N
authors.lastname: Ibis
authors.affiliation: Physical Therapy & Rehabilitation Department, Kayseri Education & Research Hospital, Atatürk Avenue, No:78, 38010 Kayseri, Turkey.
authors.forename: Sehriban
authors.initials: S
authors.lastname: Hocaoglu
authors.affiliation: Physical Therapy & Rehabilitation Department, Kayseri Education & Research Hospital, Atatürk Avenue, No:78, 38010 Kayseri, Turkey.
authors.forename: Mehtap Aykac
authors.initials: MA
authors.lastname: Cebicci
authors.affiliation: Physical Therapy & Rehabilitation Department, Kayseri Education & Research Hospital, Atatürk Avenue, No:78, 38010 Kayseri, Turkey.
authors.forename: Serap Tomruk
authors.initials: ST
authors.lastname: Sutbeyaz
authors.affiliation: Physical Therapy & Rehabilitation Department, Kayseri Education & Research Hospital, Atatürk Avenue, No:78, 38010 Kayseri, Turkey.
authors.forename: Havva Talay
authors.initials: HT
authors.lastname: Calis
mesh_terms: D000068879:Adalimumab / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D005260:Female; D006801:Humans; D011565:Psoriasis / Q000139:chemically induced* / Q000473:pathology; D013167:Spondylitis, Ankylosing / Q000188:drug therapy* / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D014409:Tumor Necrosis Factor-alpha; D000068879:Adalimumab
keywords: TNF-α inhibitors; adalimumab; anti-TNF-α drugs; palmoplantar pustular psoriasis