title: So-called carcinosarcoma of the duodenum with a chondrosarcomatous component.
abstract: Carcinosarcoma is a biphasic malignant tumor consisting of both carcinomatous and sarcomatous components, and its occurrence in the duodenum is very rare. In the present report, we describe a case of so-called carcinosarcoma of the duodenum with a chondrosarcomatous component. A 79-year-old man was referred to our hospital because of anorexia, weight loss, and jaundice. A preoperative imaging examination showed a hypovascular mass located in the pancreatic head. Histological examination of specimens obtained through a forceps biopsy revealed anaplastic carcinoma (spindle cell type), and a pancreatoduodenectomy was performed. Histologically, the tumor showed an elevated lesion with a wide base in proximity to duodenal mucosal carcinoma. The tumor was found to be predominantly composed of sarcoma with carcinomatous and chondrosarcomatous components. There was a transitional zone between the carcinomatous and sarcomatous components, and a portion of the sarcomatous component was positive for cytokeratin, and negative for vimentin. As mentioned above, we diagnosed the lesion as so-called carcinosarcoma with a chondrosarcomatous component.
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan. hirokitanaka1983@yahoo.co.jp.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tanaka
authors.affiliation: Department of Pathology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Youichirou
authors.initials: Y
authors.lastname: Baba
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Shimpei
authors.initials: S
authors.lastname: Matsusaki
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Isono
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kumazawa
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Sase
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okano
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Tomonori
authors.initials: T
authors.lastname: Saito
authors.affiliation: Department of Gastroenterology, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Katsumi
authors.initials: K
authors.lastname: Mukai
authors.affiliation: Department of Surgery, Suzuka General Hospital, 1275-53, Yamanohana, Yasuzuka, Suzuka-shi, Mie, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Taoka
mesh_terms: D000368:Aged; D002296:Carcinosarcoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D004379:Duodenal Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D008297:Male; D016577:Pancreaticoduodenectomy; D014746:Vimentin / Q000378:metabolism
chemical_list: D014746:Vimentin; D007633:Keratins
keywords: Chondrosarcoma component; Duodenum; Sarcomatoid carcinoma; So-called carcinosarcoma