title: Cytogenetic biomonitoring of occupationally exposed workers to ashes from burning of sugar cane in Ahome, Sinaloa, México.
abstract: Burning the sugar cane field before harvesting has a negative impact on both air and human health, however this issue had not been explored in Mexico. The objective of this work was to determine the chromosomal damage in workers from sugar cane burning fields in Sinaloa, México. To this purpose, we analyzed 1000 cells of buccal exfoliated epithelia from 60 exposed workers and 60 non-exposed controls to determine micronucleus frequencies and other nuclear abnormalities. The results indicated significant higher values of micronucleus and nuclear abnormalities such as binucleate cells, pyknosis, karyolysis, chromatin condensation and nuclear buds frequencies in the exposed subjects compared to those that were not exposed. Our data indicates that sugar cane burning, that generates polycyclic aromatic hydrocarbons, represents a genotoxic risk for workers in this important sugar cane producing area in Mexico.
authors.affiliation: Instituto de Investigación en Ambiente y Salud, Universidad de Occidente, Boulevard Macario Gaxiola y Carretera Internacional, Los Mochis, SIN, Mexico.
authors.forename: Carmen
authors.initials: C
authors.lastname: Martínez-Valenzuela
authors.affiliation: Instituto de Investigación en Ambiente y Salud, Universidad de Occidente, Boulevard Macario Gaxiola y Carretera Internacional, Los Mochis, SIN, Mexico.
authors.forename: Ana Rosa
authors.initials: AR
authors.lastname: Rodríguez-Quintana
authors.affiliation: Centro de Investigaciones Biomédicas, Universidad Veracruzana, Xalapa, VER, Mexico.
authors.forename: Enrique
authors.initials: E
authors.lastname: Meza
authors.affiliation: Centro de Investigaciones Biomédicas, Universidad Veracruzana, Xalapa, VER, Mexico.
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Waliszewski
authors.affiliation: Centro de Ciencias de la Atmósfera, UNAM, Circuito Exterior Ciudad Universitaria, Coyoacán 04510, México, DF, Mexico.
authors.forename: Omar
authors.initials: O
authors.lastname: Amador-Muñóz
authors.affiliation: Instituto de Investigación en Ambiente y Salud, Universidad de Occidente, Boulevard Macario Gaxiola y Carretera Internacional, Los Mochis, SIN, Mexico.
authors.forename: Arlene
authors.initials: A
authors.lastname: Mora-Romero
authors.affiliation: Centro de Ciencias de la Atmósfera, UNAM, Circuito Exterior Ciudad Universitaria, Coyoacán 04510, México, DF, Mexico.
authors.forename: María Elena
authors.initials: ME
authors.lastname: Calderón-Segura
authors.affiliation: Instituto de Investigación en Ambiente y Salud, Universidad de Occidente, Boulevard Macario Gaxiola y Carretera Internacional, Los Mochis, SIN, Mexico.
authors.forename: Rubén
authors.initials: R
authors.lastname: Félix-Gastélum
authors.affiliation: Instituto de Investigación en Ambiente y Salud, Universidad de Occidente, Boulevard Macario Gaxiola y Carretera Internacional, Los Mochis, SIN, Mexico.
authors.forename: Isabel
authors.initials: I
authors.lastname: Rodríguez-Romero
authors.affiliation: Centro de Investigaciones Biomédicas, Universidad Veracruzana, Xalapa, VER, Mexico. Electronic address: mcaba@uv.mx.
authors.forename: Mario
authors.initials: M
authors.lastname: Caba
mesh_terms: D000328:Adult; D043171:Chromosomal Instability; D003582:Cytogenetics / Q000379:methods*; D004249:DNA Damage; D004784:Environmental Monitoring / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico; D015162:Micronucleus Tests; D008875:Middle Aged; D009061:Mouth Mucosa / Q000187:drug effects*; D016273:Occupational Exposure / Q000009:adverse effects*; D031786:Saccharum; D012906:Smoke / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D012906:Smoke
keywords: HAPs; Nuclear biomarkers; Sugar cane