title: PECAS: prokaryotic and eukaryotic classical analysis of secretome.
abstract: Full sets of proteins that are transported to the extracellular space, called secretomes, have been studied for a variety of organisms to understand their potential role in crucial metabolic pathways and complex health conditions. However, there is a lack of tools for integrative classical analysis of secretomes that consider all the data sources available nowadays. Thus, PECAS (Prokaryotic and Eukaryotic Classical Analysis of Secretome) has been developed to provide a well-established prediction pipeline on secreted proteins for prokaryote and eukaryote species.
authors.affiliation: Genome Analysis Platform, CIC bioGUNE and CIBERehd, Bizkaia Technology Park, 48160, Derio, Spain.
authors.forename: Ana R
authors.initials: AR
authors.lastname: Cortazar
authors.affiliation: Genetics and Microbiology Research Group, Department of Agrarian Production, Public University of Navarre, 31006, Pamplona, Spain.
authors.forename: José A
authors.initials: JA
authors.lastname: Oguiza
authors.affiliation: Genome Analysis Platform, CIC bioGUNE and CIBERehd, Bizkaia Technology Park, 48160, Derio, Spain. amaransay@cicbiogune.es.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Aransay
authors.affiliation: Genome Analysis Platform, CIC bioGUNE and CIBERehd, Bizkaia Technology Park, 48160, Derio, Spain. jllavin@cicbiogune.es.
authors.forename: José L
authors.initials: JL
authors.lastname: Lavín
mesh_terms: D000465:Algorithms; D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism; D019295:Computational Biology; D056890:Eukaryota / Q000378:metabolism*; D005189:False Positive Reactions; D006801:Humans; D020407:Internet; D053858:Metabolic Networks and Pathways; D021382:Protein Sorting Signals; D020543:Proteome / Q000378:metabolism*; D040901:Proteomics / Q000379:methods*; D013045:Species Specificity
chemical_list: D001426:Bacterial Proteins; D021382:Protein Sorting Signals; D020543:Proteome
keywords: Analysis pipeline; Bioinformatics; Prediction; Protein secretion; Secretome; Signal peptide