title: Itching sensation and neuronal sensitivity of the skin.
abstract: BACKGROUND
  Sensitive skin is a universal term in the field of cosmetology. In addition, the development and demand for sensitive skin cosmetics is increasing. However, there is no appropriate method for detecting sensitive skin.
  
  
  METHODS
  We analyzed the relationship between the frequency of response at each sensation (stinging, burning, and itching) during a lactic acid sting test and the current perception threshold (CPT) value of each frequency. To reconfirm this relationship, we analyzed differences of the CPT value (5 Hz) between the itch responder and non-itch responder groups.
  
  
  RESULTS
  There is a significant correlation between itch sensation and CPT values of 5 Hz. The itch responder group showed significantly lower sensory perception value of 5 Hz than the non-itch responder group.
  
  
  CONCLUSIONS
  The CPT value (5 Hz) can be used for scanning for itching sensations when a cosmetic or its ingredients possibly cause the sensation.
authors.affiliation: Skin Research Center/DERMAPRO Ltd., Seoul, Korea.
authors.forename: H
authors.initials: H
authors.lastname: Ham
authors.affiliation: Skin Research Center/DERMAPRO Ltd., Seoul, Korea.
authors.forename: S M
authors.initials: SM
authors.lastname: An
authors.affiliation: Skin Research Center/DERMAPRO Ltd., Seoul, Korea.
authors.forename: E J
authors.initials: EJ
authors.lastname: Lee
authors.affiliation: Skin Research Center/DERMAPRO Ltd., Seoul, Korea.
authors.forename: E
authors.initials: E
authors.lastname: Lee
authors.affiliation: Skin Research Center/DERMAPRO Ltd., Seoul, Korea.
authors.forename: H O
authors.initials: HO
authors.lastname: Kim
authors.affiliation: Skin Research Center/DERMAPRO Ltd., Seoul, Korea.
authors.forename: J S
authors.initials: JS
authors.lastname: Koh
mesh_terms: D000328:Adult; D004056:Differential Threshold; D004558:Electric Stimulation / Q000379:methods*; D004568:Electrodiagnosis / Q000379:methods; D005260:Female; D006801:Humans; D006930:Hyperalgesia / Q000503:physiopathology*; D019344:Lactic Acid; D058748:Pain Perception; D011537:Pruritus / Q000503:physiopathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012867:Skin / Q000187:drug effects / Q000503:physiopathology*
chemical_list: D019344:Lactic Acid
keywords: CPT value; itching; neurometer; sensitive skin