title: Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods.
abstract: Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method. The crystallinity and chemical structure of synthesized nanorods were studied by Fourier transform infrared spectroscopy (FTIR), X-ray photo-electronic spectroscopy (XPS), X-ray diffraction (XRD), Raman spectroscopy, and transmission electron microscopy (TEM). The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line. The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.
authors.affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Jiangsu, 225009, China.
authors.forename: Caibao
authors.initials: C
authors.lastname: Xue
authors.forename: Yingzhi
authors.initials: Y
authors.lastname: Chen
authors.forename: Yongzhuo
authors.initials: Y
authors.lastname: Huang
authors.forename: Peizhi
authors.initials: P
authors.lastname: Zhu