title: Novel insights into a major DNA oxidative lesion: its effects on Z-DNA stabilization.
abstract: Here, we have provided novel insights into the effects of 8-oxodG substitutions on B-Z transitions of CpG dinucleotide DNAs. A combination of different techniques including a CD study, a PAGE analysis, DFT calculations and molecular modeling has been collectively used.
authors.affiliation: College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, State Key Laboratory of Virology, Wuhan University, Wuhan, Hubei 430072, P. R. China. xzhou@whu.edu.cn ttian@whu.edu.cn.
authors.forename: Jiaqi
authors.initials: J
authors.lastname: Wang
authors.forename: Shaoru
authors.initials: S
authors.lastname: Wang
authors.forename: Cheng
authors.initials: C
authors.lastname: Zhong
authors.forename: Tian
authors.initials: T
authors.lastname: Tian
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
mesh_terms: D000080242:8-Hydroxy-2'-Deoxyguanosine; D002942:Circular Dichroism; D043542:DNA, Z-Form / Q000737:chemistry*; D003849:Deoxyguanosine / Q000031:analogs & derivatives* / Q000737:chemistry; D006801:Humans; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010084:Oxidation-Reduction
chemical_list: D043542:DNA, Z-Form; D000080242:8-Hydroxy-2'-Deoxyguanosine; D003849:Deoxyguanosine