title: Angiographic Morphometry of Internal Carotid Artery Circulation in Turkish Children.
abstract: OBJECTIVE
  Knowledge of cerebrovascular morphology is integral in planning neuroendovascular interventions, especially for procedures involving placement of stents, flow diverters or stentrievers. There is insufficient data on angiographic normative values of cerebral circulation in the pediatric age group since angiograms are uncommonly performed in children except for arteriovenous malformations in which arterial dimensions are larger than normal. We aimed to measure the diameters of internal carotid circulation (ICC) arteries on digital subtraction angiograms of pediatric patients and determine the growth trends.
  
  
  METHODS
  This is a retrospective cross-sectional study measurements of ICC arteries of 64 pediatric patients (4-122 months) with retinoblastoma undergoing intra-arterial chemotherapy.
  
  
  RESULTS
  Petrous, cavernous, supraclinoid and choroidal segments of internal carotid artery (ICA) and anterior cerebral artery (ACA) diameters had significant correlation with age. Most of the growth was noted in the first 36-48 months of life. Middle cerebral artery (MCA) diameter did not show significant correlation with age. 87% of the adult diameter of the MCA was attained in the first 6 months of life. ICC arteries reached 81% to 99% of adult sizes in the first 48 months of life. On the contrary, the main iliac artery was only 59% of the adult diameter at this age group.
  
  
  CONCLUSIONS
  Use of current intracranial stents in children appears tolerable due to the growth pattern of ICC arteries. Based on this data, the current armamentarium of intracranial stents or stent-like devices is sufficient to cover the need in the pediatric population.
authors.affiliation: Baskent University, Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey.
authors.forename: Yonca Ozkan
authors.initials: YO
authors.lastname: Arat
authors.forename: Anil
authors.initials: A
authors.lastname: Arat
authors.forename: Kubilay
authors.initials: K
authors.lastname: Aydin
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D020771:Anterior Cerebral Artery / Q000033:anatomy & histology / Q000254:growth & development; D002343:Carotid Artery, Internal / Q000033:anatomy & histology* / Q000254:growth & development; D002533:Cerebral Angiography; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D020768:Middle Cerebral Artery / Q000033:anatomy & histology / Q000254:growth & development; D012016:Reference Values; D012175:Retinoblastoma / Q000601:surgery; D012189:Retrospective Studies; D015607:Stents; D014421:Turkey