title: [Neonatal Dengue. Presentation of clinical cases].
abstract: Dengue is an infectious disease caused by a flavivirus, with four serotypes, transmitted by the mosquito Aedes aegypti. In Mexico it is a public health problem, especially in the region of central and southeast of the country. The disease can be asymptomatic or present serious forms and even death. It is confirmed by detection of the NS1 Antigen; IgM antibodies, polymerase chain reaction and virus isolation. The vertical transmission to de newborn has been little studied. 7 cases in neonates from November to December 2011 are reported. All patients were male, obtained by caesarean section between 34 and 40 weeks of gestation, whose mothers were enrolled with fever and symptoms associated with dengue disease and serology positive for dengue. Six with positive AgNS1 and one positive IgM; one mother died. All the newborns had positive serology for dengue, 4 with positive AgNS1 and 3 positive IgM. The clinical features of the newborn ranged from asymptomatic to one serious dengue fever, shock and hemorrhage. The symptomatic 6 attended with thrombocytopenia, changes in temperature and unspecific disturbance. The severity of mothers conditioned disrepair product at birth, but not with subsequent gravity of the new born. Vertical trasmission of dengue should be suspected in risk areas, to maintain vigilance and to give early treatment. Also is neccesary promote the realization of specific diagnostic and therapeutic guidelines to the neonatal period.
authors.forename: Edith
authors.initials: E
authors.lastname: Romero-Santacruz
authors.forename: Janeth Jaqueline
authors.initials: JJ
authors.lastname: Lira-Canul
authors.forename: Fredy
authors.initials: F
authors.lastname: Pacheco-Tugores
authors.forename: Adolfo Gonzalo
authors.initials: AG
authors.lastname: Palma-Chan
mesh_terms: D000330:Aedes; D000818:Animals; D003715:Dengue / Q000503:physiopathology / Q000635:transmission* / Q000821:virology; D005260:Female; D005334:Fever / Q000821:virology*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D012720:Severity of Illness Index