title: The influence of flow diverter's angle of curvature across the aneurysm neck on its haemodynamics.
abstract: Flow diverter stents have provided a new method of endovascular reconstruction for large and complex aneurysms. Understanding the impact of the flow diverter's angle of curvature across the neck and its metal coverage rate on the haemodynamics of aneurysm is crucial to maximize the mass flow reduction inside the aneurysm, post-deployment. The aim of this study is to understand the correlation between the angle of curvature of flow diverter across the aneurysm neck and the metal coverage rate, and the aneurysm's haemodynamics, using computational fluid dynamics. Varying the flow diverter angle resulted in varying metal coverage rate across the aneurysm neck for two patient vessel geometries, A (straight artery) and B (curved artery) with aspect ratios of 3.1 and 2.9, respectively. The results indicate that there exists a relationship between the aneurysm's haemodynamics and the flow diverter's angle of curvature across its neck. Moreover, the calculations indicated that cases with a moderately curved flow diverter, with an associated metal coverage rate of 50%-60%, achieve maximum flow reduction inside the aneurysm due to a stable flow resistance in the direction normal to the blood flow.
authors.affiliation: Australian School of Advanced Medicine, Macquarie University, Macquarie Park, NSW, Australia.
authors.forename: Kaavya
authors.initials: K
authors.lastname: Karunanithi
authors.affiliation: Australian School of Advanced Medicine, Macquarie University, Macquarie Park, NSW, Australia.
authors.forename: Chang Joon
authors.initials: CJ
authors.lastname: Lee
authors.affiliation: Monash Medical Centre, Clayton, VIC, Australia.
authors.forename: Winston
authors.initials: W
authors.lastname: Chong
authors.affiliation: Australian School of Advanced Medicine, Macquarie University, Macquarie Park, NSW, Australia yi.qian@mq.edu.au.
authors.forename: Yi
authors.initials: Y
authors.lastname: Qian
mesh_terms: D002343:Carotid Artery, Internal / Q000503:physiopathology; D003198:Computer Simulation; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D002532:Intracranial Aneurysm / Q000503:physiopathology* / Q000601:surgery; D015607:Stents
keywords: Flow diverter angle; aneurysm neck; computational fluid dynamics; energy loss; metal coverage rate; volume flow reduction