title: Glomus Tumor of the Esophagus: A Case Report and Review of the Literature.
abstract: We report an extremely rare case of primary glomus tumor of the esophagus, and review the corresponding literature. A 66-year-old female underwent a follow-up upper-gastrointestinal endoscopy due to dysphagia and previous history of esophageal lump. Endoscopic ultrasonography revealed a mass involving the deep mucosa and submucosa (Layers 2 and 3). Endoscopic biopsy revealed a mesenchymal tumor composed of nest of epithelioid cells with associated small blood vessels proliferation. Immunohistochemically, the tumor cells were positive for alpha smooth muscle actin and vimentin, but negative for c-kit and the vascular stroma was highlighted by positivity with CD34. Pathological examination confirmed that the tumor was a glomus tumor of the esophagus. The patient remains healthy without any recurrence to date.
authors.forename: Sheila
authors.initials: S
authors.lastname: Segura
authors.forename: Sharmeen
authors.initials: S
authors.lastname: Mansoor
authors.forename: Adam B
authors.initials: AB
authors.lastname: Gorelick
authors.forename: Steven
authors.initials: S
authors.lastname: Sieber
authors.forename: Hani
authors.initials: H
authors.lastname: El-Fanek
mesh_terms: D000368:Aged; D001706:Biopsy; D004938:Esophageal Neoplasms / Q000473:pathology*; D004945:Esophagoscopy; D005260:Female; D005918:Glomus Tumor / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques