title: Receptor protein kinase FERONIA controls leaf starch accumulation by interacting with glyceraldehyde-3-phosphate dehydrogenase.
abstract: Cell expansion is coordinated by several cues, but available energy is the major factor determining growth. Receptor protein kinase FERONIA (FER) is a master regulator of cell expansion, but the details of its control mechanisms are not clear. Here we show that FER interacts with cytosolic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH, GAPC1 and GAPC2), that catalyzes a key reaction in glycolysis, which contributes to energy production. When there is an FER deficiency, there are corresponding decreases in the enzyme activity of GAPDH and increased amounts of starch. More importantly, gapc1/2 mutants mimic fer4 mutants. These data indicate that FER regulated starch content is an evolutionarily conserved function in plants that connects the cell expansion and energy metabolism pathways.
authors.affiliation: National Engineering Laboratory for Rice and By-product Deep Processing, Central South University of Forestry and Technology, Changsha, 410004, Hunan Province, PR China.
authors.forename: Tao
authors.initials: T
authors.lastname: Yang
authors.affiliation: National Engineering Laboratory for Rice and By-product Deep Processing, Central South University of Forestry and Technology, Changsha, 410004, Hunan Province, PR China; Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, PR China.
authors.forename: Long
authors.initials: L
authors.lastname: Wang
authors.affiliation: Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, PR China.
authors.forename: Chiyu
authors.initials: C
authors.lastname: Li
authors.affiliation: Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, PR China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, PR China.
authors.forename: Sirui
authors.initials: S
authors.lastname: Zhu
authors.affiliation: Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, PR China.
authors.forename: Yinyao
authors.initials: Y
authors.lastname: Qi
authors.affiliation: Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, PR China.
authors.forename: Xuanming
authors.initials: X
authors.lastname: Liu
authors.affiliation: National Engineering Laboratory for Rice and By-product Deep Processing, Central South University of Forestry and Technology, Changsha, 410004, Hunan Province, PR China. Electronic address: linql0403@126.com.
authors.forename: Qinglu
authors.initials: Q
authors.lastname: Lin
authors.affiliation: NJU-NJFU Joint Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, 210093, PR China; Department of Plant and Microbial Biology, University of California, Berkeley, CA, 94720, USA.
authors.forename: Sheng
authors.initials: S
authors.lastname: Luan
authors.affiliation: Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, PR China. Electronic address: feng_yu@hnu.edu.cn.
authors.forename: Feng
authors.initials: F
authors.lastname: Yu
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D004734:Energy Metabolism / Q000235:genetics; D018506:Gene Expression Regulation, Plant; D024581:Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) / Q000235:genetics / Q000378:metabolism*; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism; D008353:Mannitol / Q000378:metabolism / Q000494:pharmacology; D012275:Oryza / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D010770:Phosphotransferases / Q000235:genetics / Q000378:metabolism*; D018515:Plant Leaves / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D011485:Protein Binding; D036226:Seedlings / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D015398:Signal Transduction; D013213:Starch / Q000096:biosynthesis*; D013395:Sucrose / Q000378:metabolism / Q000494:pharmacology; D020798:Two-Hybrid System Techniques; D017346:Protein Serine-Threonine Kinases
chemical_list: D029681:Arabidopsis Proteins; D024581:Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); D007527:Isoenzymes; D008353:Mannitol; D010770:Phosphotransferases; D013213:Starch; D013395:Sucrose; C585192:GAPC1 protein, Arabidopsis; C522131:At3g51550 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases
keywords: FERONIA; Glyceraldehyde-3-phosphate dehydrogenase; Starch accumulation; Sucrose