title: Real-Time Respiratory Motion Analysis Using 4-D Shape Priors.
abstract: Respiratory motion analysis based on range imaging (RI) has emerged as a popular means of generating respiration surrogates to guide motion management strategies in computer-assisted interventions. However, existing approaches employ heuristics, require substantial manual interaction, or yield highly redundant information. In this paper, we propose a framework that uses preprocedurally obtained 4-D shape priors from patient-specific breathing patterns to drive intraprocedural RI-based real-time respiratory motion analysis. As the first contribution, we present a shape motion model enabling an unsupervised decomposition of respiration induced high-dimensional body surface displacement fields into a low-dimensional representation encoding thoracic and abdominal breathing. Second, we propose a method designed for GPU architectures to quickly and robustly align our models to high-coverage multiview RI body surface data. With our fully automatic method, we obtain respiration surrogates yielding a Pearson correlation coefficient (PCC) of 0.98 with conventional surrogates based on manually selected regions on RI body surface data. Compared to impedance pneumography as a respiration signal that measures the change of lung volume, we obtain a PCC of 0.96. Using off-the-shelf hardware, our framework enables high temporal resolution respiration analysis at 50 Hz.
authors.forename: Jakob
authors.initials: J
authors.lastname: Wasza
authors.forename: Peter
authors.initials: P
authors.lastname: Fischer
authors.forename: Heike
authors.initials: H
authors.lastname: Leutheuser
authors.forename: Tobias
authors.initials: T
authors.lastname: Oefner
authors.forename: Christoph
authors.initials: C
authors.lastname: Bert
authors.forename: Andreas
authors.initials: A
authors.lastname: Maier
authors.forename: Joachim
authors.initials: J
authors.lastname: Hornegger
mesh_terms: D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008176:Lung Volume Measurements; D008297:Male; D009068:Movement / Q000502:physiology; D015656:Respiratory Mechanics / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013909:Thorax / Q000000981:diagnostic imaging*