title: First-in-Man, Mitral Valve-in-Valve Transcatheter Implantation Through an Innovative Minimally Invasive Surgical Approach.
abstract: Degeneration of a surgically implanted valve bioprosthesis may occur in elderly, frail patients with an extremely high risk to undergo redo cardiac surgery. Transapical or fully percutaneous transseptal approaches have been described in order to treat degenerated aortic and mitral bioprosthesis. We performed the first-in-man successful mitral transcatheter valve delivery with a valve-in-valve technique through an innovative route; ie, a video-assisted endoscopic direct access to the left atrium, in an 82-year-old patient who previously underwent surgical replacement of the mitral valve and with a prohibitive surgical risk.
authors.affiliation: Division of Cardiac Surgery, University of Brescia Medical School, Brescia, Italy. Electronic address: munerett@med.unibs.it.
authors.forename: Claudio
authors.initials: C
authors.lastname: Muneretto
authors.affiliation: Division of Cardiology, University of Brescia Medical School, Brescia, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Ettori
authors.affiliation: Clinic for Cardiovascular Surgery, German Heart Center, Munich, Germany.
authors.forename: Domenico
authors.initials: D
authors.lastname: Mazzitelli
authors.affiliation: Division of Cardiology, University of Brescia Medical School, Brescia, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Curello
authors.affiliation: Division of Cardiology, University of Brescia Medical School, Brescia, Italy.
authors.forename: Ermanna
authors.initials: E
authors.lastname: Chiari
authors.affiliation: Section of Cardiothoracic Anesthesia, Spedali Civili, Brescia, Italy.
authors.forename: Rosy
authors.initials: R
authors.lastname: Mastropierro
authors.affiliation: Division of Cardiology, University of Brescia Medical School, Brescia, Italy.
authors.forename: Diego
authors.initials: D
authors.lastname: Maffeo
authors.affiliation: Division of Cardiac Surgery, University of Brescia Medical School, Brescia, Italy.
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Bisleri
mesh_terms: D000369:Aged, 80 and over; D001705:Bioprosthesis; D006328:Cardiac Catheterization; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures; D008943:Mitral Valve / Q000601:surgery*; D011475:Prosthesis Failure