title: Bone and bone marrow involvement in sarcoidosis.
abstract: Bone and bone marrow involvement in sarcoidosis have been infrequently reported. We aimed to describe the clinical features, radiological descriptions, pathological examinations, and outcomes of three patients with osseous sarcoidosis and one patient with bone marrow sarcoidosis seen at our institution. Our case series included fluorodeoxyglucose positron emission tomography descriptions in assessing the whole-body extent of sarcoidosis. In the era of advanced imaging, large bone and axial skeleton sarcoidosis lesions are more common than previously reported.
authors.affiliation: Department of Rheumatology, Marshfield Clinic, 1000 N. Oak Avenue, Marshfield, WI, 54449, USA. yachoui.ralph@marshfieldclinic.org.
authors.forename: Ralph
authors.initials: R
authors.lastname: Yachoui
authors.affiliation: Department of Radiology, Marshfield Clinic, 1000 N. Oak Avenue, Marshfield, WI, 54449, USA. parker.brian@marshfieldclinic.org.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Parker
authors.affiliation: Department of Lab-Pathology, Marshfield Clinic, 1000 N. Oak Avenue, Marshfield, WI, 54449, USA. nguyen.thanhcuong@marshfieldclinic.org.
authors.forename: Thanhcuong T
authors.initials: TT
authors.lastname: Nguyen
mesh_terms: D000328:Adult; D001706:Biopsy; D001847:Bone Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D001853:Bone Marrow / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology; D001855:Bone Marrow Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000008:administration & dosage; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D006811:Humerus / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology; D006886:Hydroxychloroquine / Q000008:administration & dosage; D007085:Ilium / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D010329:Patella / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology; D049268:Positron-Emission Tomography; D011241:Prednisone / Q000008:administration & dosage; D019275:Radiopharmaceuticals / Q000008:administration & dosage; D012507:Sarcoidosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome; D051598:Whole Body Imaging
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D006886:Hydroxychloroquine; D011241:Prednisone; D008727:Methotrexate
keywords: Bone; Bone diseases; Bone marrow; Granuloma; Lymph nodes; Radiography; Radionuclide imaging; Sarcoidosis/diagnosis; Sarcoidosis/etiology