title: [Hyper-immunoglobulin E syndrome: report of one case].
abstract: The Hyperimmunoglobulin E syndrome (HIES) is a rare sporadic or autosomal dominant immune and connective tissue disorder characterized by chronic eczema, cutaneous abscesses, pneumonias, invasive infections, high levels of Immunoglobulin E, primary teeth retention and bone abnormalities. We report a 24-year-old male with a history of cutaneous abscesses and esophageal candidiasis. He was admitted due to a left gluteal cellulitis. During the fifth day of hospitalization he presented a distal necrosis of the fourth finger of the right hand. Laboratory results showed high levels of IgE and positive cryoglobulins. The patient was discharged and was admitted again five days later with a new gluteal abscess. IgE levels were even higher. Applying Grimbacher scale, the diagnosis of Hyperimmunoglobulin E syndrome was reached.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Aguilera
authors.forename: Guillermo
authors.initials: G
authors.lastname: Cárcamo
authors.forename: Juan
authors.initials: J
authors.lastname: Sepúlveda
authors.forename: Ana María
authors.initials: AM
authors.lastname: Vinet
authors.forename: Carlos
authors.initials: C
authors.lastname: Martínez
mesh_terms: D000328:Adult; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D007589:Job Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D012871:Skin Diseases / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy; D055815:Young Adult
chemical_list: D007073:Immunoglobulin E