title: Design, Synthesis and Biological Evaluation of β-Carboline Dimers Based on the Structure of Neokauluamine.
abstract: The design, synthesis and biological evaluation (anticancer and antimalarial activity) of bis-β-carbolines, based on the structure of the naturally occurring alkaloid neokauluamine, is described.
authors.affiliation: Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104.
authors.forename: Jaruwan
authors.initials: J
authors.lastname: Chatwichien
authors.affiliation: The Wistar Institute, Philadelphia, PA 19104.
authors.forename: Subhasree
authors.initials: S
authors.lastname: Basu
authors.affiliation: The Wistar Institute, Philadelphia, PA 19104.
authors.forename: Maureen E
authors.initials: ME
authors.lastname: Murphy
authors.affiliation: Department of BioMolecular Sciences, University of Mississippi, University, MS 38677.
authors.forename: Mark T
authors.initials: MT
authors.lastname: Hamann
authors.affiliation: Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104.
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Winkler
keywords: Manzamine alkaloids; structure-activity relationships (SAR); β-carboline heterocycle