title: Digitalis reappraised: Still here today, but gone tomorrow?
abstract: Digoxin is one of the oldest of drugs acting on the heart and still one of the most frequently used. While in atrial fibrillation digoxin continues to have a valid role in the control of ventricular rate when added to beta-blockers and calcium antagonists, digoxin for heart failure is no longer a supportable option in view of the negative recent meta-analysis.
authors.affiliation: Research scholar, University of Cape Town, South Africa; Emeritus Director, Hatter Institute for Cardiovascular Research in Africa, Faculty of Health Sciences, University of Cape Town, South Africa. lionel.opie@uct.ac.za.
authors.forename: Lionel H
authors.initials: LH
authors.lastname: Opie
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy*; D004070:Digitalis; D004077:Digoxin / Q000627:therapeutic use*; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D028321:Plant Preparations / Q000627:therapeutic use*
chemical_list: D000889:Anti-Arrhythmia Agents; D028321:Plant Preparations; D004077:Digoxin