title: [A case of undifferentiated gastric cancer that recurred with portal vein tumor thrombus].
abstract: A 69-year-old man with a malignant tumor of the stomach underwent distal gastrectomy with partial resection of the abdominal wall, transverse colon, and lateral segment of the liver. Based on a detailed pathological examination of the resected specimen, a diagnosis of undifferentiated gastric cancer was established. Six months after the operation, during postoperative adjuvant chemotherapy with S-1, diagnostic imaging, including CT and positron emission tomography (PET), revealed a portal vein tumor thrombus and diffusely spreading metastases in the posterior segment of the liver. Despite chemotherapy with S-1/CDDP, the metastatic tumors continued to grow rapidly. The patient died 10 months after the operation. On autopsy, the portal vein tumor thrombus was observed to be composed of undifferentiated cancer cells invading into the liver parenchyma through hepatic sinusoids, with the metastatic tumors replacing 60% or more of the entire liver.
authors.affiliation: Department of Surgery, Yodogawa Christian Hospital.
authors.forename: Masahide
authors.initials: M
authors.lastname: Awazu
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Wakahara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ashitani
authors.forename: Shinobu
authors.initials: S
authors.lastname: Tsuchida
authors.forename: Nozomi
authors.initials: N
authors.lastname: Ueno
authors.forename: Akihiro
authors.initials: A
authors.lastname: Toyokawa
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Teramura
mesh_terms: D000368:Aged; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology; D008297:Male; D009360:Neoplastic Cells, Circulating / Q000473:pathology; D011169:Portal Vein; D013274:Stomach Neoplasms / Q000473:pathology*; D020246:Venous Thrombosis / Q000473:pathology*