title: Palladium-Catalyzed One-Pot Approach to 3-(Diarylmethylene)oxindoles from Propiolamidoaryl Triflate.
abstract: 3-(Diarylmethylene)oxindoles have been synthesized from propiolamidoaryl triflate utilizing a palladium-catalyzed one-pot reaction consisting of three successive reactions: Sonogashira, Heck, and Suzuki-Miyaura. This method allows for the production of a complex skeleton of 3-(diarylmethylene)oxindole from propiolamidoaryl triflate using a commercially available aryl iodide and arylboronic acid in a simple and efficient way with moderate yield and stereoselectivity.
authors.affiliation: Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Korea. dahye8821@naver.com.
authors.forename: Dahye
authors.initials: D
authors.lastname: Lee
authors.affiliation: Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Korea. sunalovegs@catholic.ac.kr.
authors.forename: Sunhwa
authors.initials: S
authors.lastname: Park
authors.affiliation: Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Korea. fbdytpq@catholic.ac.kr.
authors.forename: Yoseb
authors.initials: Y
authors.lastname: Yu
authors.affiliation: Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Korea. kyejung@catholic.ac.kr.
authors.forename: Kye Jung
authors.initials: KJ
authors.lastname: Shin
authors.affiliation: Integrated Research Institute of Pharmaceutical Sciences, College of Pharmacy, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Korea. jaehongseo@catholic.ac.kr.
authors.forename: Jae Hong
authors.initials: JH
authors.lastname: Seo
mesh_terms: D000813:Anilides / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D000078183:Oxindoles; D010165:Palladium / Q000737:chemistry*
chemical_list: D000813:Anilides; D007211:Indoles; D000078183:Oxindoles; C022960:2-oxindole; D010165:Palladium
keywords: 3-(Diarylmethylene)oxindole; aryl triflate; one-pot reaction; palladium-catalyzed reaction