title: Neurobiologically informed treatment for adults with anorexia nervosa: a novel approach to a chronic disorder.
abstract: Anorexia nervosa (AN) is a severe and debilitating disorder with significant medical and psychological sequelae. To date, there are no effective treatments for adults, resulting in high rates of chronicity, morbidity, and mortality. Recent advances in brain imaging research have led to an improved understanding of etiology and specific neurobiological mechanisms underlying symptoms. Despite this, there are no treatments focused on targeting symptoms using this empirically supported mechanistic understanding of the illness. Updated treatment approaches focused on targeting neurobiological mechanisms underlying core AN symptomatology are necessary to improve treatment out-comes for this population. Neurobiologically Enhanced With Family Eating Disorder Trait Response Treatment (NEW FED TR) is a neurobiologically informed treatment targeting key temperament constructs associated with the illness through the delivery of psychoeducation and skills training to patients and nominated carers.
authors.affiliation: University of California San Diego, Department of Psychiatry, San Diego, California, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Knatz
authors.affiliation: University of California San Diego, Department of Psychiatry, San Diego, California, USA.
authors.forename: Christina E
authors.initials: CE
authors.lastname: Wierenga
authors.affiliation: University of California San Diego, Department of Psychiatry, San Diego, California, USA.
authors.forename: Stuart B
authors.initials: SB
authors.lastname: Murray
authors.affiliation: Ohio State University, Department of Psychiatry, Columbus, Ohio, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Hill
authors.affiliation: University of California San Diego, Department of Psychiatry, San Diego, California, USA.
authors.forename: Walter H
authors.initials: WH
authors.lastname: Kaye
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis* / Q000628:therapy*; D002908:Chronic Disease; D006801:Humans; D009446:Neurobiology; D011613:Psychotherapy / Q000379:methods*
keywords: anorexia nervosa; anxiety; eating disorder; temperament; treatment