title: The clinical relevance of sexual dysfunction in systemic sclerosis.
abstract: Systemic sclerosis is a chronic multi-organ autoimmune disease, leading to important clinical and psychological implications. Among organ complications, sexual dysfunction is a major issue for both male and female gender, with high prevalence and great impact on quality of life, although frequently not addressed by both clinicians and patients. While erectile dysfunction is the most common cause of sexual problems in males, genital tract and general physical changes are major contributors to sexual impairment in females. This review presents current state of the art on this topic, discussing published data on presentation, evaluation and therapeutic options.
authors.affiliation: Dept Clinical and Experimental Medicine, Div Rheumatology, AOU Careggi, Firenze, Italy. Electronic address: cosimobruni85@gmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Bruni
authors.affiliation: Division of Rheumatology, Department and Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, Royal Free Campus, London, United Kingdom.
authors.forename: J
authors.initials: J
authors.lastname: Raja
authors.affiliation: Centre for Rheumatology and Connective Tissue Diseases, UCL Medical School, Royal Free Campus, London, United Kingdom.
authors.forename: C P
authors.initials: CP
authors.lastname: Denton
authors.affiliation: Dept Clinical and Experimental Medicine, Div Rheumatology, AOU Careggi, Firenze, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Matucci-Cerinic
mesh_terms: D000818:Animals; D002908:Chronic Disease; D006801:Humans; D015995:Prevalence; D011788:Quality of Life; D012595:Scleroderma, Systemic / Q000150:complications*; D012725:Sexual Behavior; D012735:Sexual Dysfunction, Physiological / Q000209:etiology* / Q000628:therapy
keywords: Erectile dysfunction; Sexual dysfunction; Systemic sclerosis