title: Nano-Based Anti-Tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis.
abstract: Nanotechnology has shown great promise in health care offering numerous possibilities to significantly improve diagnosis of many dreadful diseases including Tuberculosis (TB). Nanomedicine has made the current drug regimen more effective against diseases particularly TB with attributes like sustained release, increased half life, higher drug concentrations at target sites, reduced toxicity and lesser side effects. However because of the severity of the disease, there is a strong urge to develop better approaches with some concomitant regimens using nano-particles to diagnose, treat and manage TB patients. The current review highlights some of the evolving strategies in the field of nanomedicine particularly drug delivery offering promising alternative for the current TB regimens. The study also emphasizes upon the need to design more effective nanocarriers which are highly specific, biocompatible and biodegradable as well.
authors.forename: Rohit
authors.initials: R
authors.lastname: Sharma
authors.forename: Amanpreet
authors.initials: A
authors.lastname: Kaur
authors.forename: A K
authors.initials: AK
authors.lastname: Sharma
authors.forename: Neeraj
authors.initials: N
authors.lastname: Dilbaghi
authors.affiliation: Department of Biotechnology, Maharishi Markandeshwar University, Mullana-Ambala-133207, Haryana - 133207, India.
authors.forename: Anil K
authors.initials: AK
authors.lastname: Sharma
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D016503:Drug Delivery Systems / Q000379:methods*; D006207:Half-Life; D006801:Humans; D049329:Nanostructures; D016896:Treatment Outcome; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents