title: Tackling Cell Transplantation Anoikis: An Injectable, Shape Memory Cryogel Microcarrier Platform Material for Stem Cell and Neuronal Cell Growth.
abstract: Highly macroporous semisynthetic cryogel microcarriers can be synthesized for culturing stem cells and neuronal type cells. Growth factors loaded to heparin-containing microcarriers show near zero-order release kinetics and cell-loaded microcarriers can be injected through a fine gauge cannula without negative effect on the cells. These carriers can be applied for cell transplantation applications.
authors.affiliation: Leibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.|Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, Wales, UK.
authors.forename: Ben
authors.initials: B
authors.lastname: Newland
authors.affiliation: Leibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
authors.forename: Petra B
authors.initials: PB
authors.lastname: Welzel
authors.affiliation: Leibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
authors.forename: Heike
authors.initials: H
authors.lastname: Newland
authors.affiliation: Leibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
authors.forename: Claudia
authors.initials: C
authors.lastname: Renneberg
authors.affiliation: Leibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
authors.forename: Petr
authors.initials: P
authors.lastname: Kolar
authors.affiliation: Leibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
authors.forename: Mikhail
authors.initials: M
authors.lastname: Tsurkan
authors.affiliation: Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, Wales, UK.
authors.forename: Anne
authors.initials: A
authors.lastname: Rosser
authors.affiliation: Leibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
authors.forename: Uwe
authors.initials: U
authors.lastname: Freudenberg
authors.affiliation: Leibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
authors.forename: Carsten
authors.initials: C
authors.lastname: Werner
mesh_terms: D000818:Animals; D023102:Anoikis / Q000187:drug effects*; D002465:Cell Movement / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D017690:Cell Transplantation; D059985:Cryogels / Q000494:pharmacology*; D007267:Injections; D008863:Microspheres; D009474:Neurons / Q000166:cytology* / Q000187:drug effects; D016716:PC12 Cells; D051381:Rats; D055647:Rats, Transgenic; D013234:Stem Cells / Q000166:cytology* / Q000187:drug effects
chemical_list: D059985:Cryogels
keywords: adherent matrix; biomaterials; cryogels; heparin; microcarriers; neurotrophin; shape memory; star-PEG