title: Combined Coronary Artery Bypass Grafting and Abdominal Aortic Aneurysm Repair: Presentation of 3 Cases and a Review of the Literature.
abstract: BACKGROUND
  Coronary artery disease and abdominal aortic aneurysmal disease can occur in a single patient, and a therapeutic conundrum presents when open surgical repair is indicated for both conditions. The traditional standard of care is to conduct coronary artery bypass grafting (CABG) followed by abdominal aortic aneurysm (AAA) repair 2-6 months later, but there is significant risk with staging these 2 major surgeries. An alternative method is to surgically repair both diseases in 1 combined operation. The aim of our study is to review our own experience with the combined procedure and to review the published literature to assess morbidity and mortality of combined CABG and AAA repair.
  
  
  METHODS
  A systematic search for relevant studies was performed in the PubMed/Medline database. Short-term mortality (<30 days) and postoperative complications were assessed from relevant case series from 1993 to 2013. We also conducted a retrospective chart review of all patients undergoing the combined procedure at our institution.
  
  
  RESULTS
  Thirty case series with a total of 369 patients averaged a 30-day mortality of 3.0%. Fourteen percent and 6% of patients experienced a cardiovascular or respiratory complication, respectively. Other postoperative events included acute renal failure (7%) and superficial wound complications (5%). In our own experience, 3 patients underwent combined CABG and AAA repair. The mean age was 71 years, the average AAA size was 8.9 cm, and average operative time was 328 min. None experienced any postoperative complications. Two are still alive at 9 and 10 years after surgery, and 1 died of unrelated causes 8 years postoperatively.
  
  
  CONCLUSIONS
  The results of this systematic review suggest that combined CABG and AAA repair is a viable procedure with low operative mortality. Patients with preserved ejection fractions, large AAA, and limited comorbidities appear to receive the most benefit from a combined approach based on reported data from the literature. We have experienced promising results in our highly selected patient population. More research is warranted to devise criteria to determine which patients would be good surgical candidates for this combined procedure.
authors.affiliation: Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, MI. Electronic address: amw@msu.edu.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Williams
authors.affiliation: Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, MI; Department of Surgery, Spectrum Health Medical Group, Grand Rapids, MI.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Watson
authors.affiliation: Department of Surgery, Michigan State University College of Human Medicine, Grand Rapids, MI; Department of Surgery, Spectrum Health Medical Group, Grand Rapids, MI.
authors.forename: M Ashraf
authors.initials: MA
authors.lastname: Mansour
authors.affiliation: Department of Surgery, Spectrum Health Medical Group, Grand Rapids, MI.
authors.forename: George T
authors.initials: GT
authors.lastname: Sugiyama
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000601:surgery*; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000150:complications / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged