title: The adaptive statistical iterative reconstruction-V technique for radiation dose reduction in abdominal CT: comparison with the adaptive statistical iterative reconstruction technique.
abstract: OBJECTIVE
  To investigate whether reduced radiation dose abdominal CT images reconstructed with adaptive statistical iterative reconstruction V (ASIR-V) compromise the depiction of clinically competent features when compared with the currently used routine radiation dose CT images reconstructed with ASIR.
  
  
  METHODS
  27 consecutive patients (mean body mass index: 23.55 kg m(-2) underwent CT of the abdomen at two time points. At the first time point, abdominal CT was scanned at 21.45 noise index levels of automatic current modulation at 120 kV. Images were reconstructed with 40% ASIR, the routine protocol of Dong-A University Hospital. At the second time point, follow-up scans were performed at 30 noise index levels. Images were reconstructed with filtered back projection (FBP), 40% ASIR, 30% ASIR-V, 50% ASIR-V and 70% ASIR-V for the reduced radiation dose. Both quantitative and qualitative analyses of image quality were conducted. The CT dose index was also recorded.
  
  
  RESULTS
  At the follow-up study, the mean dose reduction relative to the currently used common radiation dose was 35.37% (range: 19-49%). The overall subjective image quality and diagnostic acceptability of the 50% ASIR-V scores at the reduced radiation dose were nearly identical to those recorded when using the initial routine-dose CT with 40% ASIR. Subjective ratings of the qualitative analysis revealed that of all reduced radiation dose CT series reconstructed, 30% ASIR-V and 50% ASIR-V were associated with higher image quality with lower noise and artefacts as well as good sharpness when compared with 40% ASIR and FBP. However, the sharpness score at 70% ASIR-V was considered to be worse than that at 40% ASIR. Objective image noise for 50% ASIR-V was 34.24% and 46.34% which was lower than 40% ASIR and FBP.
  
  
  CONCLUSIONS
  Abdominal CT images reconstructed with ASIR-V facilitate radiation dose reductions of to 35% when compared with the ASIR.
  
  
  CONCLUSIONS
  This study represents the first clinical research experiment to use ASIR-V, the newest version of iterative reconstruction. Use of the ASIR-V algorithm decreased image noise and increased image quality when compared with the ASIR and FBP methods. These results suggest that high-quality low-dose CT may represent a new clinical option.
authors.affiliation: Department of Radiology, Dong-A University Hospital, Busan, Republic of Korea.
authors.forename: Heejin
authors.initials: H
authors.lastname: Kwon
authors.affiliation: Department of Radiology, Dong-A University Hospital, Busan, Republic of Korea.
authors.forename: Jinhan
authors.initials: J
authors.lastname: Cho
authors.affiliation: Department of Radiology, Dong-A University Hospital, Busan, Republic of Korea.
authors.forename: Jongyeong
authors.initials: J
authors.lastname: Oh
authors.affiliation: Department of Radiology, Dong-A University Hospital, Busan, Republic of Korea.
authors.forename: Dongwon
authors.initials: D
authors.lastname: Kim
authors.affiliation: Department of Radiology, Dong-A University Hospital, Busan, Republic of Korea.
authors.forename: Junghyun
authors.initials: J
authors.lastname: Cho
authors.affiliation: Department of Radiology, Dong-A University Hospital, Busan, Republic of Korea.
authors.forename: Sanghyun
authors.initials: S
authors.lastname: Kim
authors.affiliation: Department of Radiology, Dong-A University Hospital, Busan, Republic of Korea.
authors.forename: Sangyun
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Radiology, Dong-A University Hospital, Busan, Republic of Korea.
authors.forename: Jihyun
authors.initials: J
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D011860:Radiography, Abdominal / Q000379:methods*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*; D055815:Young Adult