title: Correlation between the sorption of dissolved oxygen onto chitosan and its antimicrobial activity against Esherichia coli.
abstract: The ability of chitosan to adsorb dissolved oxygen from solution depends on its physical shape and is related to the surface area. Depending on conditions chitosan is capable of adsorbing or releasing oxygen. Chitosan, modificated by the substances possessing antimicrobial activity, such as succinic acid, Pd(II) ions, metallic Pd or Ag, distinctly increases the ability to adsorb the dissolved oxygen. The additional treatment of chitosan with air oxygen or electrochemically produced oxygen also increases the uptake of dissolved oxygen by chitosan. A strong correlation between the amount of oxygen adsorbed onto chitosan and its antimicrobial activity against Esherichia coli has been observed. This finding suggests that one of the sources of antimicrobial activity of chitosan is the ability to sorb dissolved oxygen, along with other well-known factors such as physical state and chemical composition.
authors.affiliation: Center for Physical Sciences and Technology, A. Goštauto str. 9, LT-01108 Vilnius, Lithuania. Electronic address: gyliene@ktl.mii.lt.
authors.forename: Ona
authors.initials: O
authors.lastname: Gylienė
authors.affiliation: Nature Research Centre, Akademijos 2, LT-08412 Vilnius, Lithuania.
authors.forename: Elena
authors.initials: E
authors.lastname: Servienė
authors.affiliation: Nature Research Centre, Akademijos 2, LT-08412 Vilnius, Lithuania.
authors.forename: Iglė
authors.initials: I
authors.lastname: Vepštaitė
authors.affiliation: Center for Physical Sciences and Technology, A. Goštauto str. 9, LT-01108 Vilnius, Lithuania.
authors.forename: Rima
authors.initials: R
authors.lastname: Binkienė
authors.affiliation: Center for Physical Sciences and Technology, A. Goštauto str. 9, LT-01108 Vilnius, Lithuania.
authors.forename: Mykolas
authors.initials: M
authors.lastname: Baranauskas
authors.affiliation: Nature Research Centre, Akademijos 2, LT-08412 Vilnius, Lithuania.
authors.forename: Juliana
authors.initials: J
authors.lastname: Lukša
mesh_terms: D000327:Adsorption; D000890:Anti-Infective Agents / Q000494:pharmacology; D048271:Chitosan / Q000494:pharmacology*; D004202:Disinfectants / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D050296:Microbial Viability / Q000187:drug effects; D008855:Microscopy, Electron, Scanning; D010100:Oxygen / Q000494:pharmacology*; D012995:Solubility
chemical_list: D000890:Anti-Infective Agents; D004202:Disinfectants; D048271:Chitosan; D010100:Oxygen
keywords: Antimicrobial activity; Chitosan; Oxygen sorption