title: Hidradenitis Suppurativa and Wound Management.
abstract: Hidradenitis suppurativa (HS) is a chronic, burdensome, debilitating disease of the hair follicle. It presents with recurrent painful inflamed and noninflamed lesions usually in specific body areas such as axillary, inguinal, perineal, and genital areas. It is associated with a large range of other diseases and conditions, such as obesity, arthropathy, inflammatory bowel diseases, and sqaumous cell carcinoma. Medical therapy may be systemic or topical, mainly based on antibiotics, retinoids, hormones and immunosuppressive drugs, including biological therapies. Surgical and laser therapies may be a valid therapeutic approach in order to treat locally recurring lesions. The aim of this article is to review the wound healing options after skin excision and laser treatments, with a focus on lesions left to heal by secondary intention, analyzing the efficacy of moist wound dressings, negative pressure wound therapy, bioactive dressings, such as platelet-rich plasma gel and hylarunoic acid scaffold, or autologous keratinocyte suspension in platelet concentrate and skin-grafting tecniques.
authors.affiliation: University of Pisa, Pisa, Italy valentina.dini@unipi.it.
authors.forename: Valentina
authors.initials: V
authors.lastname: Dini
authors.affiliation: University of Pisa, Pisa, Italy.
authors.forename: Teresa
authors.initials: T
authors.lastname: Oranges
authors.affiliation: University of Pisa, Pisa, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Rotella
authors.affiliation: University of Pisa, Pisa, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Romanelli
mesh_terms: D019468:Disease Management; D017497:Hidradenitis Suppurativa / Q000628:therapy*; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods*; D012008:Recurrence; D014945:Wound Healing
keywords: acne inversa; hidradenitis suppurativa; wound care