title: Common parameters of acupuncture for the treatment of hypertension used in animal models.
abstract: Hypertension is associated with at least 7.6 million annual deaths worldwide. While pharmacotherapy may provide good control for blood pressure, it sometimes induces adverse effects. Meanwhile, acupuncture has been used for the treatment of cardiovascular diseases, such as hypertension, coronary artery disease, and stroke, but its mechanisms of actions remain poorly understood. The efficacy of acupuncture depends on multiple constituent elements including acupoints, manipulation skills, and implementation programs, which are termed as acupuncture prescription. This review summarized the previous information of experimental use of acupuncture on animals including species, hypertension models, acupoints selection, acupoint location, stimulation protocols, and evaluation of effectiveness to provide useful guidance for researchers when performing acupuncture in animal experiments.
authors.forename: Shengfeng
authors.initials: S
authors.lastname: Lu
authors.forename: Xin
authors.initials: X
authors.lastname: Cao
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ohara
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Hiroko
authors.initials: H
authors.lastname: Izumi-Nakaseko
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ando
authors.forename: Wanxin
authors.initials: W
authors.lastname: Liu
authors.forename: Atsushi
authors.initials: A
authors.lastname: Sugiyama
authors.forename: Bingmei
authors.initials: B
authors.lastname: Zhu
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000818:Animals; D002415:Cats; D006224:Cricetinae; D004195:Disease Models, Animal; D004285:Dogs; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D011817:Rabbits; D051381:Rats