title: Guidelines for the management of Helicobacter pylori infection in Italy: The III Working Group Consensus Report 2015.
abstract: Knowledge on the role of Helicobacter pylori (HP) infection is continually evolving, and treatment is becoming more challenging due to increasing bacterial resistance. Since the management of HP infection is changing, an update of the national Italian guidelines delivered in 2007 was needed. In the III Working Group Consensus Report 2015, a panel of 17 experts from several Italian regions reviewed current evidence on different topics relating to HP infection. Four working groups examined the following topics: (1) "open questions" on HP diagnosis and treatment (focusing on dyspepsia, gastro-oesophageal reflux disease, non-steroidal anti-inflammatory drugs or aspirin use and extra-gastric diseases); (2) non-invasive and invasive diagnostic tests; (3) treatment of HP infection; (4) role of HP in the prevention of gastric cancer. Statements and recommendations were discussed and a consensus reached in a final plenary session held in February 2015 in Bologna. Recommendations are based on the best current evidence to help physicians manage HP infection in Italy. The guidelines have been endorsed by the Italian Society of Gastroenterology and the Italian Society of Digestive Endoscopy.
authors.affiliation: Department of Medical and Surgical Sciences, University of Bologna, Italy. Electronic address: roccomaurizio.zagari@unibo.it.
authors.forename: Rocco Maurizio
authors.initials: RM
authors.lastname: Zagari
authors.affiliation: Department of Clinical and Experimental Medicine "F. Magrassi", Second University of Naples, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Romano
authors.affiliation: Department of Internal Medicine and Gastroenterology, Catholic University, Rome, Italy.
authors.forename: Veronica
authors.initials: V
authors.lastname: Ojetti
authors.affiliation: Department of Internal Medicine, University of Ferrara, Italy.
authors.forename: Reinhold
authors.initials: R
authors.lastname: Stockbrugger
authors.affiliation: School of Gastroenterology, University of Ferrara, Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Gullini
authors.affiliation: Department of Digestive and Liver Disease, University Sapienza, Rome, Italy.
authors.forename: Bruno
authors.initials: B
authors.lastname: Annibale
authors.affiliation: Department of Surgery, Oncology and Gastroenterology, Section of Gastroenterology, University of Padua, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Farinati
authors.affiliation: Department of Emergency and Organ Transplantation, University of Bari, Italy.
authors.forename: Enzo
authors.initials: E
authors.lastname: Ierardi
authors.affiliation: Gastroenterology Unit, Department of Biomedical and Clinical Sciences, L. Sacco University Hospital, Milan, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Maconi
authors.affiliation: Department of Medicine, Surgical Pathology and Cytopathology Unit, University of Padua, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Rugge
authors.affiliation: Department of Medical and Surgical Sciences, University of Bologna, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Calabrese
authors.affiliation: Department of Clinical and Experimental Medicine, University of Parma, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Di Mario
authors.affiliation: Department of Health Science, University of Catanzaro "Magna Graecia", Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Luzza
authors.affiliation: Internal Medicine A, Maggiore Hospital, Bologna, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Pretolani
authors.affiliation: Fondazione Poliambulanza, Department of Histopathology, Brescia, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Savio
authors.affiliation: Department of Internal Medicine and Gastroenterology, Catholic University, Rome, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Gasbarrini
authors.affiliation: School of Gastroenterology, University of Ferrara, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Caselli
mesh_terms: D000658:Amoxicillin / Q000627:therapeutic use; D000863:Antacids / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000942:Antigens, Bacterial / Q000032:analysis; D001471:Barrett Esophagus / Q000150:complications; D001729:Bismuth / Q000627:therapeutic use*; D001944:Breath Tests; D017291:Clarithromycin / Q000627:therapeutic use; D019468:Disease Management; D004359:Drug Therapy, Combination; D004415:Dyspepsia / Q000150:complications; D005243:Feces; D005764:Gastroesophageal Reflux / Q000150:complications; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016480:Helicobacter pylori; D007558:Italy; D064704:Levofloxacin / Q000627:therapeutic use; D008795:Metronidazole / Q000627:therapeutic use; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000517:prevention & control*; D014508:Urea
chemical_list: D000863:Antacids; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000942:Antigens, Bacterial; D054328:Proton Pump Inhibitors; D008795:Metronidazole; D064704:Levofloxacin; D000658:Amoxicillin; D014508:Urea; D017291:Clarithromycin; D001729:Bismuth
keywords: Guidelines; Helicobacter pylori; Italy; Management