title: Choosing the tool for osteoporosis risk prediction.
abstract: OBJECTIVE
  Predicting fracture risk is a major challenge because it allows the prevention of major osteoporotic fracture in high-risk populations. With the aging of the population, this matter will become of even greater importance. In recent years, novel clinical, biochemical, and imaging tools have been developed to improve the assessment of fracture risk.
  
  
  RESULTS
  The present review summarizes novel clinical strategies, Dual energy X-ray absorptiometry (DXA)-derived tools, imaging techniques, and biochemical markers that have been developed recently to improve fracture risk prediction.
  
  
  CONCLUSIONS
  DXA and clinical fracture risk prediction tools are preferential markers of fracture risk. Clinical fracture risk alone might be used if DXA facilities are unavailable. The fracture risk assessment tool may be used in osteoporosis consultation in many countries. Other tools may be used soon after more studies are performed, particularly trabecular bone score, quantitative ultrasound, bone turnover markers. Specific factors for example falls, hip axis length, vertebral fracture assessment could be used in individual patients. This may significantly improve the clinical decision-making.
authors.affiliation: aDepartment of Rheumatology A, Cochin Hospital bPhysiology Department, Necker-Enfants-Malades Hospital, Paris Descartes University, Paris, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Cormier
authors.forename: Eugenie
authors.initials: E
authors.lastname: Koumakis
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Souberbielle
mesh_terms: D015502:Absorptiometry, Photon; D000058:Accidental Falls; D015415:Biomarkers / Q000032:analysis; D015519:Bone Density; D006801:Humans; D010024:Osteoporosis / Q000150:complications*; D058866:Osteoporotic Fractures / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors
chemical_list: D015415:Biomarkers