title: Stress Tolerance Variations in Saccharomyces cerevisiae Strains from Diverse Ecological Sources and Geographical Locations.
abstract: The budding yeast Saccharomyces cerevisiae is a platform organism for bioethanol production from various feedstocks and robust strains are desirable for efficient fermentation because yeast cells inevitably encounter stressors during the process. Recently, diverse S. cerevisiae lineages were identified, which provided novel resources for understanding stress tolerance variations and related shaping factors in the yeast. This study characterized the tolerance of diverse S. cerevisiae strains to the stressors of high ethanol concentrations, temperature shocks, and osmotic stress. The results showed that the isolates from human-associated environments overall presented a higher level of stress tolerance compared with those from forests spared anthropogenic influences. Statistical analyses indicated that the variations of stress tolerance were significantly correlated with both ecological sources and geographical locations of the strains. This study provides guidelines for selection of robust S. cerevisiae strains for bioethanol production from nature.
authors.affiliation: College of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao, 266590, China.
authors.forename: Yan-Lin
authors.initials: YL
authors.lastname: Zheng
authors.affiliation: Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Energy Genetics, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, China.
authors.forename: Shi-An
authors.initials: SA
authors.lastname: Wang
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics*; D018533:Biomass; D002681:China; D017753:Ecosystem; D000431:Ethanol / Q000378:metabolism / Q000494:pharmacology; D005285:Fermentation; D014644:Genetic Variation; D005843:Geography; D007218:Industrial Microbiology / Q000379:methods; D009997:Osmotic Pressure; D010802:Phylogeny; D012441:Saccharomyces cerevisiae / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism; D013045:Species Specificity; D013312:Stress, Physiological / Q000235:genetics*; D013696:Temperature
chemical_list: D029701:Saccharomyces cerevisiae Proteins; D000431:Ethanol