title: A Delayed Finding of a Tracheal Cartilaginous Sleeve in a Patient with Pfeiffer Syndrome Type 2 and a Complex Airway History.
abstract: Persistent airway obstruction symptoms in a 2½-year-old boy with Pfeiffer syndrome were attributed to facial abnormalities, central and obstructive sleep apnea, and tracheomalacia from a vascular ring. These findings delayed the diagnosis of a tracheal cartilaginous sleeve. Life expectancy in tracheal cartilaginous sleeve is improved by tracheostomy. Tracheal cartilaginous sleeve should be considered and investigated through airway endoscopy in children with fibroblast growth factor receptor-related craniosynostosis syndromes.
authors.affiliation: From the Departments of *Anesthesiology and †Otolaryngology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas.
authors.forename: Camille
authors.initials: C
authors.lastname: Colomb
authors.forename: Helena Karlberg
authors.initials: HK
authors.lastname: Hippard
authors.forename: Karina
authors.initials: K
authors.lastname: Canadas
authors.forename: Mehernoor
authors.initials: M
authors.lastname: Watcha
mesh_terms: D000015:Abnormalities, Multiple / Q000601:surgery*; D000168:Acrocephalosyndactylia; D000402:Airway Obstruction / Q000209:etiology* / Q000601:surgery; D002675:Child, Preschool; D003398:Craniosynostoses / Q000235:genetics; D006330:Heart Defects, Congenital; D006801:Humans; D008297:Male; D017468:Receptors, Fibroblast Growth Factor / Q000235:genetics; D014132:Trachea / Q000002:abnormalities*; D014139:Tracheostomy
chemical_list: D017468:Receptors, Fibroblast Growth Factor