title: Noninfectious Complications of Peritoneal Dialysis in Korean Children: A 26-Year Single-Center Study.
abstract: OBJECTIVE
  The aim of this study was to investigate noninfectious complications of peritoneal dialysis (PD), including mechanical and metabolic complications, at a single center in Korea.
  
  
  METHODS
  We analyzed data from 60 PD patients aged ≤18 years (40 boys and 20 girls) during the period between 1986 and 2012. The collected data included gender, age, causes of PD, incidence of noninfectious complications, and treatment for the complications.
  
  
  RESULTS
  The mean duration of PD therapy was 28.7±42.1 months (range 1-240 months). The most common cause of end-stage renal disease was glomerular disease (43.3%). There were no statistically significant differences between patients with and without mechanical complications regarding gender, age at the start of PD, and total duration of PD. Outflow failure was the most common catheter-related complication (14.3%), followed by leakage (10.0%) and hernia (8.6%). Metabolic complications, such as hyperglycemia and hypokalemia, were observed in three of 16 patients. The frequency of noninfectious complications of PD in our study was comparable with those in previous pediatric studies. PD was switched to hemodialysis (HD) in only three patients.
  
  
  CONCLUSIONS
  Our results indicate that noninfectious complications of PD are common, though they hardly lead to catheter removal or HD in pediatric patients on PD.
authors.affiliation: Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.|Department of Pediatric Nephrology, Severance Children's Hospital, Seoul, Korea.
authors.forename: Ji Eun
authors.initials: JE
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Ajou University School of Medicine, Daewoo General Hospital, Geoje, Korea.
authors.forename: Se Jin
authors.initials: SJ
authors.lastname: Park
authors.affiliation: Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.|Department of Pediatric Nephrology, Severance Children's Hospital, Seoul, Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Oh
authors.affiliation: Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Ji Hong
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jae Seung
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Pyung Kil
authors.initials: PK
authors.lastname: Kim
authors.affiliation: Department of Pediatric Nephrology, Severance Children's Hospital, Seoul, Korea.|Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea. shinji@yuhs.ac.
authors.forename: Jae Il
authors.initials: JI
authors.lastname: Shin
mesh_terms: D000293:Adolescent; D044466:Asian People; D002404:Catheterization / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D020878:Device Removal; D005260:Female; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D010043:Outcome and Process Assessment, Health Care; D010530:Peritoneal Dialysis / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods*; D006435:Renal Dialysis / Q000009:adverse effects; D056910:Republic of Korea; D016896:Treatment Outcome
keywords: Peritoneal dialysis; children; noninfectious complication