title: Umbilical Cord Tissue-Derived Cells as Therapeutic Agents.
abstract: Although the characteristics of SC, including UC-derived cells, are a dramatically discussed issue, this review will focus particularly on some controversial issues regarding clinical utility of cells isolated from UC tissue. UC-derived cells have several advantages compared to other types and sources of stem cells. The impact of UC topography on cell characteristics is briefly discussed. The necessity to adapt existing methods of cell isolation and culturing to GMP conditions is mentioned, as well as possible cryopreservation of this material. Light is shed on some future perspectives for UC-derived cells.
authors.affiliation: National Taras Shevchenko University of Kyiv, Kyiv, Ukraine ; Hemafund Ltd., Lisozakhysna Street 5, Kyiv, Ukraine.
authors.forename: Olga
authors.initials: O
authors.lastname: Maslova
authors.affiliation: International Clinical Research Center, St. Anne's University Hospital and Masaryk University, Pekarska 53, 656 91 Brno, Czech Republic.
authors.forename: Miroslav
authors.initials: M
authors.lastname: Novak
authors.affiliation: International Clinical Research Center, St. Anne's University Hospital and Masaryk University, Pekarska 53, 656 91 Brno, Czech Republic.
authors.forename: Peter
authors.initials: P
authors.lastname: Kruzliak