title: [Effect of Electroacupuncture at "Yanglingquan" (GB 34) Acupoint on White Blood Cell Count and Gallbladder Wall Thickness in Rabbits with Acute Cholecystitis].
abstract: OBJECTIVE
  To observe the effects of electroacupuncture (EA) at "Yanglingquan"(GB 34) acupoint on white blood cell (WBC) count and gallbladder wall thickness in rabbits with acute cholecystitis, so as to explore the inherent correlation between the gallbladder and GB 34 acupoint according to the theory of Chinese medicine.
  
  
  METHODS
  Thirty-two male rabbits were randomly and equally divided into control group, model group, EA "Yanglingquan"(GB 34) group (EA-GB 34) and EA "Yinlingquan"(SP 9) group (EA-SP 9). The acute cholecystitis model was induced by intra-gallbladder injection of escherichia coli liquid. EA stimulation was delivered once per day for consecutive 7 days. WBC count and gallbladder wall thickness were measured to assess the effects of EA treatment. HE staining was carried out to examine the pathological changes of the gallbladder tissue.
  
  
  RESULTS
  Compared with the control group,WBC count and gallbladder wall thickness of the model group were significantly increased (P<0. 05), and those changes were reversed by EA intervention at either GB 34 or SP 9 acupoints (P<0. 05). As to WBC count, there was no significant difference between EA-GB 34 and EA-SP 9 groups (P>0. 05), whereas for reducing gallbladder wall thickness, EA stimulation at GB 34 acupoint resulted in a better effect than that of EA at SP 9 acupoint (P<0. 05).
  
  
  CONCLUSIONS
  EA produces positive therapeutic benefits on acute cholecystitis in rabbits. It seems that stimulation at "Yan - glingquan" acupoint gives rise to a better effect than that of "Yinlingquan" acupoint in particular for the reduction of gallbladder wall thickhess.
authors.forename: Ming-liang
authors.initials: ML
authors.lastname: Zhou
authors.forename: Wen-rui
authors.initials: WR
authors.lastname: Jia
authors.forename: Jian-tong
authors.initials: JT
authors.lastname: Wang
authors.forename: Pei
authors.initials: P
authors.lastname: Wang
authors.forename: Li-hong
authors.initials: LH
authors.lastname: Guo
authors.forename: Ming-he
authors.initials: MH
authors.lastname: Sui
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D041881:Cholecystitis, Acute / Q000503:physiopathology / Q000628:therapy*; D004195:Disease Models, Animal; D015671:Electroacupuncture; D005704:Gallbladder / Q000503:physiopathology*; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D011817:Rabbits