title: Temporo-mandibular joint chondrosarcoma: Case report and review of the literature.
abstract: Chondrosarcoma is a malignant mesenchymal tumour of cartilaginous origin. It represents 11% of all malignant primary bone tumours, and the pelvis, ribs, femur and humerus are most frequently involved. Chondrosarcoma of the head and neck region is a rare disease, and represents approximately 0.1% of all head and neck neoplasms. This report describes a rare localisation of chondrosarcoma in a 56-year-old man who presented with swelling in the right preauricular area and mild limitation and pain in the mouth opening. Since 1959, just a few cases of temporomandibular joint (TMJ) chondrosarcoma have been described. Computed tomography revealed a large mass (39 x 46 x 40 mm) in the right preauricular and parotid region with morpho-structural alterations of the condyle and an intense periostotic reaction. The tumour was treated by total parotidectomy and condylotomy. The VII cranial nerve was preserved. Histopathologic examination revealed a low grade chondrosarcoma with a 50% proliferation index. At present, the patient is still receiving routine follow-up after radiotherapy and physiotherapy.
authors.affiliation: Department of Otorhinolaryngology, Tor Vergata University Hospital, Rome, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Giorgione
authors.affiliation: Department of Otorhinolaryngology, Tor Vergata University Hospital, Rome, Italy.
authors.forename: F M
authors.initials: FM
authors.lastname: Passali
authors.affiliation: Department of Otorhinolaryngology, Tor Vergata University Hospital, Rome, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Varakliotis
authors.affiliation: Department of Otorhinolaryngology, Tor Vergata University Hospital, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Sibilia
authors.affiliation: Department of Otorhinolaryngology, Tor Vergata University Hospital, Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Ottaviani
mesh_terms: D002813:Chondrosarcoma / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013704:Temporomandibular Joint
keywords: Bone tumour; Chondrosarcoma; Temporomandibular joint