title: [Antibiotics utilization in the Intensive Care Unit of the Hospital Dr, Guillermo Rawson-San Juan, Argentina].
abstract: BACKGROUND
  To achieve rational use of antibiotics (ATB), is necessary to know its use and prescription patterns over time, Objective: To describe and analyze the characteristics of the use of ATB in the Guillermo Rawson Hospital (GRH) adult intensive care unit (ICU).
  
  
  METHODS
  Observational, descriptive, longitudinal and retrospective study (2008-2011). Pharmacy and Statistics records were consulted, ATC code was used, the group analyzed was J01, Oral or parenteral DDD were assigned, Data was processed with Excel 2007, Unit of measure: DDD/100 bed-days, for each ATB per year and an average of use.
  
  
  CONCLUSIONS
  Over 4 years, 48 different medicines were dispensed (33 drugs), The average consumption of ATB was 177,07 DDD/100 bed-days and distribution per year was: 183,10, 165,90, 180,94, 178,34, The DDD/100 bed-days average for treatment groups more used were: penicillin (57.10), other β-lactam antibacterials (48.01), other antibacterials (21.07), trimethoprim and sulfonamides (19,54), quinolones (15,64), macrolides/azalides and lincosamides (6,53), aminoglycosides (5,65) and tetracyclines (3,53), There were changes in consumption without clear pattern of increase or decrease.
  
  
  CONCLUSIONS
  ATB used in the ICU and its variation in use between 2008-2011 were described, The ATB most used were penicillins and other β-lactams and 2008 was the year that more ATB was dispensed. Understanding these patterns of consumption will be useful to develop a founded antibiotic policy reached by consensus and beneficial to the patients.
authors.forename: Elena María
authors.initials: EM
authors.lastname: Vega
authors.forename: Daniela
authors.initials: D
authors.lastname: Fontana
authors.forename: Martha
authors.initials: M
authors.lastname: Iturrieta
authors.forename: Liliana
authors.initials: L
authors.lastname: Segovia
authors.forename: Gabriela
authors.initials: G
authors.lastname: Rodríguez
authors.forename: Sandra
authors.initials: S
authors.lastname: Agüero
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001118:Argentina; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D008137:Longitudinal Studies; D012189:Retrospective Studies
chemical_list: D000900:Anti-Bacterial Agents