title: [Toxoplasma gondi Antibody Profile in Patients with Leukemia or Lymphoma].
abstract: Blood samples were collected from patients with leukemia (n = 150) or lymphoma (n = 150) in the Cancer Hospital from March to September 2014. The specific antibodies (IgG, IgM) to, and circulating antigens (CAg) of Toxoplasma gondii were determined by ELISA. A 529 bp specific sequence was amplified by PCR from the genomic DNA of T. gondii. T. gondii-specific IgG positive rate in patients with leukemia and lymphoma were 16.0% (24/150) and 20.0% (30/150), respectively, which were significantly higher than that of healthy persons (6.4%, 7/110) (P < 0.05). IgM positive rate of the leukemia patients, lymphoma patients, and healthy persons was 2.7% (4/150), 1.3% (2/150), and 0.9% (1/110) (P > 0.05), respectively. No significant difference was found in IgM and CAg positive rate among leukemia patients, lymphoma patients, and healthy persons (P > 0.05). No specific band (529 bp) was detected in all samples.
authors.forename: Meng-yuan
authors.initials: MY
authors.lastname: Tian
authors.forename: Yun-hong
authors.initials: YH
authors.lastname: Huang
authors.forename: Yun-fei
authors.initials: YF
authors.lastname: Hu
authors.forename: Feng-tao
authors.initials: FT
authors.lastname: Peng
authors.forename: Cai-yan
authors.initials: CY
authors.lastname: Zou
authors.forename: Yong-nian
authors.initials: YN
authors.lastname: Li
mesh_terms: D000913:Antibodies, Protozoan; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007074:Immunoglobulin G; D007938:Leukemia; D008223:Lymphoma; D016133:Polymerase Chain Reaction; D014122:Toxoplasma
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G