title: Rh(III)-Catalyzed Trifluoromethylthiolation of Indoles via C-H Activation.
abstract: Cp*Rh(III) complexes have been applied as efficient catalysts for the C-H activation and trifluoromethylthiolation of indoles functionalized with a heterocycle. With N-trifluoromethylthiosaccharin being an electrophilic SCF3 reagent, this C-S coupling occurred selectively at the 2-position with good functional group tolerance.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Xie
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
authors.forename: Xingwei
authors.initials: X
authors.lastname: Li
mesh_terms: D002384:Catalysis; D006860:Hydrogen Bonding; D007202:Indicators and Reagents / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D012439:Saccharin / Q000031:analogs & derivatives* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007202:Indicators and Reagents; D007211:Indoles; D008698:Mesylates; C000598006:N-trifluoromethylthiosaccharin; D012238:Rhodium; D012439:Saccharin