Stressing about misplaced fat is a key to longevity.
The abnormal accumulation of fat increases the lifespans of nematodes that lack sex cells.
Department of Physiology, University of California, San Francisco, United States.
George A
GA
Lemieux
Department of Physiology, University of California, San Francisco, United States.
Kaveh
K
Ashrafi
D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D005786:Gene Expression Regulation; D005854:Germ Cells / Q000502:physiology*; D050356:Lipid Metabolism; D014157:Transcription Factors / Q000378:metabolism*
D029742:Caenorhabditis elegans Proteins; D004268:DNA-Binding Proteins; D014157:Transcription Factors
C. elegans; SKN-1/Nrf; aging; cell biology; chromosomes; fatty acid signaling; genes; germline stem cells; lipid metabolism; proteostasis