Multiple Colon Ulcers with Typical Small Intestinal Lesions Induced by Non-Steroidal Anti-Inflammatory Drugs.
The diagnosis of NSAID-induced colon ulcers is difficult when the distribution or endoscopic findings are not typical. An 83-year-old woman was transferred to our hospital for hemorrhagic diarrhea. Colonoscopy showed multiple ulcers in the entire colon, particularly longitudinal ulcers in the transverse colon. These were unusual for NSAID-induced colopathy, although she had been on meloxicam. However, capsule endoscopy revealed multiple scars and erosions, characteristic of NSAIDs users. The final diagnosis was NSAID-induced enteropathy, and all lesions were in remission after meloxicam discontinuation. We herein emphasize the value of an endoscopic assessment of the entire digestive tract in the diagnosis of NSAID-induced mucosal lesions.
Department of Gastroenterology and Hematology, Faculty of Medicine, University of Toyama, Japan.
Momoko
M
Akashi
Takayuki
T
Ando
Takeru
T
Hamashima
Hiroki
H
Yoshita
Sohachi
S
Nanjo
Hiroshi
H
Mihara
Haruka
H
Fujinami
Shinya
S
Kajiura
Jun
J
Nishikawa
Yoshiaki
Y
Miura
Ayumu
A
Hosokawa
Toshiro
T
Sugiyama
D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D053704:Capsule Endoscopy; D003106:Colon / Q000187:drug effects / Q000473:pathology*; D003113:Colonoscopy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007421:Intestine, Small / Q000187:drug effects / Q000473:pathology*; D000077239:Meloxicam; D013843:Thiazines / Q000008:administration & dosage / Q000009:adverse effects*; D013844:Thiazoles / Q000008:administration & dosage / Q000009:adverse effects*; D014456:Ulcer / Q000139:chemically induced*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013843:Thiazines; D013844:Thiazoles; D000077239:Meloxicam