Human Monkeypox in the Kivus, a Conflict Region of the Democratic Republic of the Congo.
Monkeypox (MPX) is a zoonotic Orthopoxvirus infection endemic in central and western Africa. Human MPX cases occur in the central and northern regions of the Democratic Republic of the Congo (DRC), and this is the first report of confirmed MPX cases in the forested areas of North and South Kivu Provinces, with a detailed epidemiological investigation for one case. The location of each case is within areas predicted to be suitable for MPX virus transmission based on an ecological niche model. Phylogenetic analysis places these viruses in the Congo Basin clade.
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo azv4@cdc.gov.
Andrea M
AM
McCollum
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Yoshinori
Y
Nakazawa
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Guy Mutombo
GM
Ndongala
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Elisabeth
E
Pukuta
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Stomy
S
Karhemere
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Robert Shongo
RS
Lushima
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Benoit Kebela
BK
Ilunga
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Joelle
J
Kabamba
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Kimberly
K
Wilkins
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jinxin
J
Gao
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Yu
Y
Li
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Ginny
G
Emerson
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Inger K
IK
Damon
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Darin S
DS
Carroll
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Mary G
MG
Reynolds
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jean
J
Malekani
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia; Division Provinciale de la Santé, Ministère de la Santé Publique, Goma, Nord-Kivu, Democratic Republic of the Congo; Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo; Ministère de la Santé Publique, Kinshasa, Democratic Republic of the Congo; U.S. Centers for Disease Control and Prevention, Kinshasa, Democratic Republic of the Congo; University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Jean-Jacques Muyembe
JJ
Tamfum
D000328:Adult; D002648:Child; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D045908:Mpox, Monkeypox / Q000453:epidemiology*; D008993:Monkeypox virus / Q000235:genetics; D010802:Phylogeny; D014857:Warfare; D055815:Young Adult