Coexistence of multiple myeloma and clear cell renal cell carcinoma: a case report and review of literature.
Coexistence of multiple myeloma (MM) and renal cell carcinoma (RCC) is an extremely rare condition. Nevertheless, there is a higher than expected incidence of co-occurrence of these two malignancies. Several case series, in the recent past, have postulated an association between MM and RCC. Population-based data analyses have revealed a bi-directional association between these two malignancies. However, the cause still remains speculative up to date. Here, we aim to describe a patient with MM and clear cell renal cell carcinoma (CCRCC) one after another for the second time from China. Clinical implications are discussed with a critical review of existing literature and we expect to draw much more awareness among clinicians regarding such association.
Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou Zhejiang, People's Republic of China.
Gaixiang
G
Xu
Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou Zhejiang, People's Republic of China.
Min
M
Yang
Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou Zhejiang, People's Republic of China.
Jian
J
Huang
Department of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou Zhejiang, People's Republic of China.
Jie
J
Jin
D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D002292:Carcinoma, Renal Cell / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D014408:Biomarkers, Tumor
Multiple myeloma; clear cell renal cell carcinoma; interferon-a; interleukin (IL)-6