[PERSONALIZED MEDICINE: NEW CHALLENGES FOR THE PHYSICIAN].
The clinician has to cope with new advances in medicine. Traditional medicine, which is based upon pathophysiological reasoning and clinical experience, has been reinforced by evidence-based medicine, which relies on levels of evidence provided by controlled clinical trials carried out on cohorts of patients. Since a few years, personalized medicine has been put at the forefront. A therapy tailored to every patient, if possible characterized by biomarkers, among which, since the achievement of the whole human genome sequencing, an increasing number of genetic markers. Personalized medicine should be used as a complement of traditional and evidence-based medicine. Physicians should progressively integrate this new strategy in their therapeutic approach. Hence, clinicians have to face new challenges as far as scientific knowledge, practical applications and physician-patient relationship are concerned.
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D003191:Comprehensive Health Care / Q000379:methods; D006801:Humans; D019359:Knowledge; D018802:Patient-Centered Care / Q000592:standards / Q000639:trends; D010819:Physician's Role; D010817:Physician-Patient Relations; D010818:Practice Patterns, Physicians' / Q000639:trends; D057285:Precision Medicine / Q000379:methods / Q000639:trends