In vitro efficacy of allicin on chicken Eimeria tenella sporozoites.
Chicken coccidiosis is a major parasitic disease caused by Eimeria spp. It is controlled and treated using chemical anticoccidial agents. Development of partial or complete resistance toward these anticoccidials is considered a major problem in poultry industry. Allicin is an organosulfur compound produced as a result of the reaction between alliin and alliinase after hacking of garlic. In this study, tenfold dilution from 180 mg/ml to 1.8 ng/ml of allicin in distilled water was tested against E. tenella in vitro. The percent of inhibition in allicin was from 99.9 to 71.53% using 180 mg/ml and 180 ng/ml, respectively. The percent of inhibition was 56.24% using 1.8 ng/ml. We used allicin as a treatment from plants against chicken coccidiosis; however, in vivo study should be performed to confirm these results.
Institute of Parasitology, Centre of Infectious Diseases, Faculty of Veterinary Medicine, University of Leipzig, An den Tierkliniken 35, 04103, Leipzig, Germany.
Alaa Aldin
AA
Alnassan
Ahmed
A
Thabet
Arwid
A
Daugschies
Berit
B
Bangoura
D000818:Animals; D002645:Chickens / Q000469:parasitology; D003048:Coccidiosis / Q000188:drug therapy* / Q000469:parasitology; D003049:Coccidiostats / Q000008:administration & dosage*; D004220:Disulfides; D016786:Eimeria tenella / Q000187:drug effects* / Q000254:growth & development; D005737:Garlic / Q000737:chemistry*; D010936:Plant Extracts / Q000008:administration & dosage*; D011201:Poultry Diseases / Q000188:drug therapy* / Q000469:parasitology; D034101:Sporozoites / Q000187:drug effects / Q000254:growth & development; D013441:Sulfinic Acids / Q000008:administration & dosage*
D003049:Coccidiostats; D004220:Disulfides; D010936:Plant Extracts; D013441:Sulfinic Acids; C006452:allicin