Sinonasal carcinoma presenting as chronic sinusitis and sequential bilateral visual loss.
Sinonasal undifferentiated carcinoma-related rhinogenic optic neuropathy is rare and may lead to visual loss. To the best of our knowledge, this is the first report of bilateral sequential visual loss induced by this etiology. It is important to differentiate between chronic sinusitis and malignancy on the basis of specific findings on magnetic resonance images. Surgical decompression with multidisciplinary therapy, including steroids, chemotherapy, and radiotherapy, is indicated. However, no visual improvement was noted in this case, emphasizing the rapid disease progression and importance of early diagnosis and treatment.
Wei-Yu
WY
Chiang
Meng-Hsiang
MH
Chen
Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China.
Hsiu-Mei
HM
Huang
D000368:Aged; D002277:Carcinoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D002908:Chronic Disease; D019299:Decompression, Surgical; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008444:Maxillary Sinus Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D009900:Optic Nerve / Q000000981:diagnostic imaging*; D009901:Optic Nerve Diseases / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D012852:Sinusitis / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed / Q000379:methods; D015354:Vision, Low / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery