Reductions of aryl bromides in water at room temperature.
Micellar nanoreactors derived from commercially available 'Nok' (SPGS-550-M), in the presence of Fu's catalyst and a mild hydride source (NaBH4), are useful for facile debromination of functionalized aromatic derivatives. This mild and environemntally responsible process is utlized in water at room temperature, and the reaction mixtures can be smoothly recycled.
Department of Chemistry and Biochemistry, University of California, Santa Barbara 93106 USA.
James C
JC
Fennewald
Department of Chemistry and Biochemistry, University of California, Santa Barbara 93106 USA.
Evan B
EB
Landstrom
Department of Chemistry and Biochemistry, University of California, Santa Barbara 93106 USA.
Bruce H
BH
Lipshutz
Functional group tolerance; Green chemistry; Micellar catalysis; Mild debromination; Recycling