Phytochemical and Botanical Therapies for Rosacea: A Systematic Review.
Botanical and cosmeceutical therapies are commonly used to treat symptoms of rosacea such as facial erythema, papules/pustule counts, and telangiectasia. These products may contain plant extracts, phytochemicals, and herbal formulations. The objective of this study was to review clinical studies evaluating the use of botanical agents for the treatment of rosacea. MEDLINE and Embase databases were searched for clinical studies evaluating botanical therapies for rosacea. Major results were summarized, and study methodology was analyzed. Several botanical therapies may be promising for rosacea symptoms, but few studies are methodologically rigorous. Several plant extract and phytochemicals effectively improved facial erythema and papule/pustule counts caused by rosacea. Many studies are not methodologically rigorous. Further research is critical, as many botanicals have been evaluated in only one study. Botanical agents may reduce facial erythema and effectively improve papule/pustule counts associated with rosacea. Although promising, further research in the area is imperative.
Department of Dermatology, University of California-Davis, Sacramento, CA, USA.
Whitney A
WA
Fisk
Department of Dermatology, Albert Einstein College of Medicine, Bronx, NY, USA.
Hadar A
HA
Lev-Tov
School of Medicine, University of California-Davis, Sacramento, CA, USA.
Ashley K
AK
Clark
Department of Dermatology, University of California-Davis, Sacramento, CA, USA.
Raja K
RK
Sivamani
D004890:Erythema / Q000188:drug therapy; D064209:Phytochemicals; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D012393:Rosacea / Q000628:therapy*
D064209:Phytochemicals; D010936:Plant Extracts
ROSACEA; alternative; botanical; herbs; phytochemical; plants