Acute Submandibular Swelling Complicating Arteriography With Iodide Contrast: A Case Report and Literature Review.
Iodide mumps is an uncommon condition induced by iodide-containing contrast. We present the first reported case of iodide mumps in mainland China, which occurred after carotid artery intervention.The patient, a 65-year-old Chinese male, had a history of dizziness, hypertension, diabetes, and right arm weakness. He had no history of allergies and had never previously received iodide-containing contrast. The patient's kidney function and other laboratory findings were normal. He underwent stenting of the left internal carotid artery (LICA) opening and received approximately 250 mL of a nonionic contrast agent (ioversol). Approximately 5 hours after angioplasty, bilateral local swellings were noted near the mandible; the masses were moderately firm and nontender.Iodide mumps was diagnosed in the patient. Intravenous dexamethasone (10 mg) was administered. The submandibular glands had shrunk by 11 hours after angioplasty, and they gradually became softer. The mandibular salivary glands had completely recovered by 5 days after surgery.Iodide mumps represents a rare late reaction to iodine-containing contrast media. This condition can occur in any patient receiving any iodinated contrast agent and may recur upon repeated exposure, but self-resolution can be expected within 2 weeks. All clinicians who use contrast media or iodide should be aware of this condition.
From the Department of Neurology, Second Affiliated Hospital, Medical School of Xi'an Jiaotong University (GZ, RZ, YG, ZM, HW, TL); Department of Stomatology, Affiliated Children's Hospital, Medical School of Xi'an Jiaotong University, Xi'an (YL); and Department of Neurology, Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi Province, China (LZ).
Guilian
G
Zhang
Yaqi
Y
Li
Ru
R
Zhang
Yingying
Y
Guo
Zhulin
Z
Ma
Huqing
H
Wang
Lei
L
Zhang
Tingting
T
Li
D000368:Aged; D000792:Angiography / Q000009:adverse effects* / Q000379:methods; D020520:Brain Infarction / Q000175:diagnosis / Q000209:etiology; D016893:Carotid Stenosis / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects; D003907:Dexamethasone / Q000008:administration & dosage*; D057510:Endovascular Procedures / Q000009:adverse effects* / Q000379:methods; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008297:Male; D012469:Salivary Glands / Q000000981:diagnostic imaging / Q000187:drug effects; D015607:Stents; D013364:Submandibular Gland Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014283:Triiodobenzoic Acids / Q000008:administration & dosage / Q000009:adverse effects; D018615:Ultrasonography, Doppler, Color
D003287:Contrast Media; D005938:Glucocorticoids; D014283:Triiodobenzoic Acids; D003907:Dexamethasone; C054871:ioversol