Transition-metal-catalyzed hydrogen-transfer annulations: access to heterocyclic scaffolds.
The ability of hydrogen-transfer transition-metal catalysts, which enable increasingly rapid access to important structural scaffolds from simple starting materials, has led to a plethora of research efforts on the construction of heterocyclic scaffolds. Transition-metal-catalyzed hydrogen-transfer annulations are environmentally benign and highly atom-economical as they release of water and hydrogen as by-product and utilize renewable feedstock alcohols as starting materials. Recent advances in this field with respect to the annulations of alcohols with various nucleophilic partners, thus leading to the formation of heterocyclic scaffolds, are highlighted herein.
Catalysis Division, CSIR-National Chemical Laboratory (CSIR-NCL), Dr. Homi Bhabha Road, Pune, 411008 (India). avnandakumar@gmail.com.|Organic Chemistry Division, Central Leather Research Institute (CSIR-CLRI), Adyar, Chennai, 600 020 (India). avnandakumar@gmail.com.
Avanashiappan
A
Nandakumar
Catalysis Division, CSIR-National Chemical Laboratory (CSIR-NCL), Dr. Homi Bhabha Road, Pune, 411008 (India).
Siba Prasad
SP
Midya
Catalysis Division, CSIR-National Chemical Laboratory (CSIR-NCL), Dr. Homi Bhabha Road, Pune, 411008 (India).
Vinod Gokulkrishna
VG
Landge
Catalysis Division, CSIR-National Chemical Laboratory (CSIR-NCL), Dr. Homi Bhabha Road, Pune, 411008 (India). eb.raman@ncl.res.in, balaramane2002@yahoo.com.
Ekambaram
E
Balaraman
D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D028561:Transition Elements / Q000737:chemistry*
D006571:Heterocyclic Compounds; D028561:Transition Elements; D006859:Hydrogen
annulations; heterocycles; hydrogen transfer; synthetic methods; transition metal catalysis