Sc(OTf)3-Catalyzed [3 + 3] Cycloaddition of Cyclopropane 1,1-Diesters with Phthalazinium Dicyanomethanides.
The Sc(OTf)3-catalyzed diastereoselective [3 + 3] cycloaddition of phthalazinium dicyanomethanides with cyclopropane 1,1-diesters proceeded smoothly under mild reaction conditions, affording a variety of 3,4-dihydro-1H-pyrido[2,1-a]phthalazine derivatives in up to 99% yields with excellent diastereoselectivities.
Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.
Honglei
H
Liu
Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.
Chunhao
C
Yuan
Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.
Yang
Y
Wu
Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.
Yumei
Y
Xiao
Department of Applied Chemistry, China Agricultural University , Beijing 100193, P. R. China.
Hongchao
H
Guo