Evaluation of Wound Healing Efficacy of an Antimicrobial Spray Dressing at Skin Donor Sites.
BACKGROUND
Autologous skin transplantation is a common treatment for patients with full-thickness burns. Postoperative wound care is essential for skin graft donor and recipient sites, but traditional wound dressings such as cotton and gauze do not form an effective barrier to bacteria, and patients can feel uncomfortable when replacing dressings.


METHODS
The goal of this study was to evaluate the use of an antimicrobial spray dressing (JUC Spray Dressing, NMS Technologies Co Ltd, Nanjing, China), with respect to its antimicrobial efficiency and the degree of pain experienced by patients.


RESULTS
The authors found the antimicrobial spray can reduce pain during the recovery period, while providing equivalent antibacterial protection to the control treatment (AQUACEL Hydrofiber Wound Dressing, ConvaTec, Bridgewater, NJ) based on skin culture tests. The spray did not adversely affect the wound site recovery. No significant side effects were present during the treatment period.


CONCLUSIONS
This antimicrobial spray could potentially be used in wound dressing applications.
Department of Orthopedics, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan, ROC.
Lien-Guo
LG
Dai
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Keng-Yen
KY
Fu
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Pai-Shan
PS
Hsieh
Institute of Polymer Science and Engineering, National Taiwan University, Taipei, Taiwan, ROC.
Yu-Min
YM
Hung
Department of Biology and Anatomy, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC; Burn Center, Tri-Service General Hospital, Taipei, Taiwan, ROC.
Yi-Wen
YW
Wang
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Li-Chaun
LC
Hsia
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Shun-Cheng
SC
Chang
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Chih-Hsin
CH
Wang
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Shou-Cheng
SC
Teng
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Shyi-Gen
SG
Chen
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Tim-Mo
TM
Chen
Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Niann-Tzyy
NT
Dai
D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D002056:Burns / Q000628:therapy; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D010146:Pain / Q000188:drug therapy; D016038:Skin Transplantation / Q000009:adverse effects*; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects*
D000890:Anti-Infective Agents