Diuretics for hypertension: Hydrochlorothiazide or chlorthalidone?
Thiazide diuretics are the cornerstone of treatment of hypertension in most patients. Hydrochlorothiazide is the most commonly used thiazide diuretic in the United States, but interest in chlorthalidone is increasing. The authors summarize the literature comparing these two agents.
Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.
Danielle
D
Cooney
Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.
Sherry
S
Milfred-LaForest
Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.|University Hospitals Case Medical Center, Cleveland OH, USA. E-mail: Mahboob.Rahman@uhhospitals.org.
Mahboob
M
Rahman
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002752:Chlorthalidone / Q000627:therapeutic use*; D004232:Diuretics / Q000627:therapeutic use*; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use*; D006973:Hypertension / Q000188:drug therapy*
D000959:Antihypertensive Agents; D004232:Diuretics; D006852:Hydrochlorothiazide; D002752:Chlorthalidone