[NONINVASIVE DIAGNOSTICS OF THE PHENOTYPE OF GASTRITIS: ANALISIS OF THE FIRST THOUSAND OF CASES].
The analysis of noninvasive diagnostics of a phenotype of gastritis among 1050 people aged from 18 till 80 years which consistently addressed to policlinic is presented in the article. The instrument of diagnostics was a <<GastroPanel>>, including a complex of biomarkers - so-called <<serological biopsy>> (pepsinogen I, pepsinogen II, gastrin-17 and IgG- antibodies to Helicobacter Pylori). High frequency of different variants of atrophic gastritis (25%) with a gastric cancer risk and conditions with a risk of erosive and ulcer damages of the stomach mucous (26 %) was shown. Clinical and economical expediency of noninvasive screening of a phenotype of gastritis is postulated.
A V
AV
Belkovets
S A
SA
Kurilovich
O
O
Reshetnikov
Yu I
YI
Ragino
L V
LV
Scherbakova
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood*; D005260:Female; D005755:Gastrins / Q000097:blood*; D005756:Gastritis / Q000097:blood / Q000175:diagnosis; D016480:Helicobacter pylori; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D020116:Pepsinogen A / Q000097:blood*; D020115:Pepsinogen C / Q000097:blood*; D012189:Retrospective Studies
D000907:Antibodies, Bacterial; D005755:Gastrins; D007074:Immunoglobulin G; C013550:gastrin 17; D020115:Pepsinogen C; D020116:Pepsinogen A