[Exploring effective components of laxative effect of Anemarrhenae Rhizoma based on Chinese herbal processing theory].
Anemarrhena asphodeloides processed by salt and raw product was compared including both chemical composition and laxative function in order to find the possible active substance to cure constipation. Processed and raw Anemarrhenae laxative effect on experimental constipation models was observed as well as chemical composition using UPLC-MS technology and the total sugar content was determined by phenol sulfuric acid method. Processed Anemarrhenae water extract improved excrement more than raw which has significant difference compared with the blank group (P < 0.05). On the other hand, the total ion flow spectrum showed no significant difference in most substance, but the total sugar content was significantly higher than raw product. Anemarrhenae ancient be recognized benefitting for draining body water in traditional Chinese medicine which has been lost in modern books because it is manifested as excellent laxative effect not diuretic effect. Saccharides carbohydrate may have closely relationship with this magically effect.
Xia
X
Lei
Jie
J
Zhang
Yuan
Y
Li
Qiu-hong
QH
Wang
Juan
J
Xue
Xiao-lin
XL
Su
Chang-fu
CF
Wang
Yong-gang
YG
Xia
Hai-xue
HX
Kuang
D031403:Anemarrhena / Q000737:chemistry*; D000818:Animals; D002626:Chemistry, Pharmaceutical; D003248:Constipation / Q000188:drug therapy* / Q000503:physiopathology; D003672:Defecation / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry*; D006801:Humans; D054368:Laxatives / Q000008:administration & dosage / Q000737:chemistry*; D008297:Male; D017208:Rats, Wistar; D027343:Rhizome / Q000737:chemistry
D004365:Drugs, Chinese Herbal; D054368:Laxatives