Three new iridoids from two Viburnum species.
Three new iridoids, 10-deacetyl suspensolide A aglycone (1), 7-deacetyl suspensolide A aglycone (2), and 7,10-dideacetyl suspensolide A aglycone (3), were isolated from two species of Viburnum. Their structures were elucidated on the basis of spectroscopic methods, including 1D and 2D NMR techniques. Compound 2 exhibited moderate anti-inflammatory activity against NO production in LPS-stimulated RAW 264.7 cells with IC50 of 17.2 μM.
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.|b University of the Chinese Academy of Sciences , Beijing 100049 , China.
Min
M
Fan
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.|b University of the Chinese Academy of Sciences , Beijing 100049 , China.
Yu-Cheng
YC
Liu
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.|b University of the Chinese Academy of Sciences , Beijing 100049 , China.
Wei-Wei
WW
Jiang
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
Jia
J
Su
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
Xing-De
XD
Wu
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
Li-Yan
LY
Peng
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
Xiao
X
Cheng
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
Juan
J
He
a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650204 , China.
Qin-Shi
QS
Zhao
D000818:Animals; D020128:Inhibitory Concentration 50; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D051379:Mice; D015394:Molecular Structure; D009569:Nitric Oxide / Q000096:biosynthesis; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D027925:Viburnum / Q000737:chemistry*
C000604666:10-deacetyl suspensolide A aglycone; C000604668:7,10-dideacetyl suspensolide A aglycone; C000604667:7-deacetyl suspensolide A aglycone; D039823:Iridoids; D009569:Nitric Oxide
10-deacetyl suspensolide A aglycone; 10-dideacetyl suspensolide A aglycone; 7; 7-deacetyl suspensolide A aglycone; Viburnum; iridoids