[New oral anticoagulants and endoscopy--what do you have to consider?].
Anti-coagulated patients often undergo endoscopic procedures and non-vitamin-K-antagonist oral anticoagulants (NOAC) are increasingly prescribed. Consequently, a comprehensive knowledge about the adequate peri-interventional handling of these substances is required. A standardized approach needs to be planned for elective and emergency situations. As a result of their pharmacokinetics, the peri-endoscopic management of NOAC is relatively easy - an heparin "bridging"/"switching" is usually not required. In case of a severe NOAC bleeding endoscopic treatment must be considered at an early stage.
Bereich Gastroenterologie, Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus, TU Dresden.
Sven
S
Pannach
Universitäts GefäßCentrum, Universitätsklinikum Carl Gustav Carus, TU Dresden.
Jan
J
Beyer-Westendorf
D000284:Administration, Oral; D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects* / Q000493:pharmacokinetics; D057915:Drug Substitution; D004632:Emergency Medical Services; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects*; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced* / Q000517:prevention & control*; D006493:Heparin / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D010347:Patient Care Planning
D000925:Anticoagulants; D006493:Heparin