Anthrax Toxins in Context of Bacillus anthracis Spores and Spore Germination.
The interaction of anthrax toxin or toxin components with B. anthracis spores has been demonstrated. Germinating spores can produce significant amounts of toxin components very soon after the initiation of germination. In this review, we will summarize the work performed that has led to our understanding of toxin and spore interactions and discuss the complexities associated with these interactions.
United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Bacteriology Division, 1425 Porter Street, Fort Detrick, Frederick, MD 21702-5011, USA. christopher.k.cote.civ@mail.mil.
Christopher K
CK
Cote
United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Bacteriology Division, 1425 Porter Street, Fort Detrick, Frederick, MD 21702-5011, USA. susan.l.welkos.civ@mail.mil.
Susan L
SL
Welkos
D000818:Animals; D000908:Antibodies, Fungal / Q000276:immunology; D000942:Antigens, Bacterial / Q000276:immunology / Q000378:metabolism*; D001408:Bacillus anthracis / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology*; D001427:Bacterial Toxins / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D008264:Macrophages / Q000276:immunology; D013171:Spores, Bacterial / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology*
D000908:Antibodies, Fungal; D000942:Antigens, Bacterial; D001427:Bacterial Toxins; C030325:anthrax toxin
Bacillus anthracis; PA; anthrax; anthrax toxins; germination; spores