[PHARMACONUTRITION IN SEVERELY ILL PATIENT].
"Pharmaconutrient" is a term applicable to those compounds which. in addition to their nutritional function, play a role as aids in the treatment of patients with severe pathologies, including sepsis, trauma, burns and major surgery, In general, enrichment of enteral an parenteral formulas with pharmaconutrients contribute to positively modulate the inflammatory response, infection and controlling the internal milieu, which in turn can be evaluated through lower mortality, hospital and intensive care units stay, days of mechanical ventilation and other parameters allowing to asses their effects. Arginine, glutamine, nucleotides, omega-3 fatty acids and antioxidant micronutrients, make up the nucleus of pharmaconutrients used with that aim, usually as mixtures of them. In the present review current evidence about the effects, indications, limitations, doses, potential adverse risks and even counter-indications is analysed.
Hospital Universitario Vall´Hebron, Barcelona (España).. antonioj.perez.sspa@juntadeandalucia.es.
Rosa
R
Burgos Peláez
Hospital Infanta Sofia. San Sebastian de los Reyes, Madrid (España).. antonioj.perez.sspa@juntadeandalucia.es.
Elena
E
Escudero Álvarez
Hospital Universitario Virgen de la Victoria, Málaga (España).. antonioj.perez.sspa@juntadeandalucia.es.
Jose Manuel
JM
García Almeida
Hospital Universitario de la Paz, Madrid (España).. antonioj.perez.sspa@juntadeandalucia.es.
Abelardo
A
García de Lorenzo
Hospital Universitario Virgen del Rocio, Sevilla (España).. antonioj.perez.sspa@juntadeandalucia.es.
Pedro Pablo
PP
García Luna
Facultad de Farmacia de la Universidad de Granada, Granada (España).. antonioj.perez.sspa@juntadeandalucia.es.
Angel
A
Gil Hernández
Complejo Hospitalario Doctor Arnulfo Arias Madrid, Ciudad de Panamá (Panamá).. antonioj.perez.sspa@juntadeandalucia.es.
Alfredo
A
Matos Adames
Hospital de Linares, Jaén (España).. antonioj.perez.sspa@juntadeandalucia.es.
Juan Bautista
JB
Molina Soria
Hospital Universitario 12 de Octubre, Madrid (España).. antonioj.perez.sspa@juntadeandalucia.es.
Juan Carlos
JC
Montejo González
Hospital General Universitarío Reina Sofía. Murcia (España).. antonioj.perez.sspa@juntadeandalucia.es.
Carmen
C
Sánchez Alvarez
Hospital Universitario Virgen de las Nieves, Granada (España).. antonioj.perez.sspa@juntadeandalucia.es.
Antonio
A
Perez de la Cruz
D003422:Critical Care / Q000379:methods*; D016638:Critical Illness / Q000628:therapy*; D004358:Drug Therapy; D006801:Humans; D007362:Intensive Care Units; D044623:Nutrition Therapy; D010288:Parenteral Nutrition