Diagnosis of Dual Malignancy by 18F-FDG PET/CT in the Setting of Paraneoplastic Cerebellar Degeneration.
We describe a rare case of paraneoplastic cerebellar degeneration (with detectable antineuronal antibody anti-Yo) in which (18)F-FDG PET/CT aided in the detection of 2 synchronous malignancies (one thyroid cancer and the other breast cancer). Interestingly, the primary breast malignancy was non-(18)F-FDG-avid and was detected through the presence of a metastatic (18)F-FDG-avid axillary lymph node. Surgery for both was undertaken in the same sitting, and there was improvement of the neurologic features soon after the surgical removal of the malignancies.
Radiation Medicine Centre (BARC), TMH Annexe, Mumbai, India.
Pradeep
P
Thapa
Radiation Medicine Centre (BARC), TMH Annexe, Mumbai, India drsanb@yahoo.com.
Sandip
S
Basu
D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D020362:Paraneoplastic Cerebellar Degeneration / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000072078:Positron Emission Tomography Computed Tomography; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery
D019788:Fluorodeoxyglucose F18
18F-FDG-PET/CT; paraneoplastic cerebellar degeneration; paraneoplastic neurological syndrome (PNS)