[The correlation between the levels of cortisol and free radical oxidation in patients with heroin addiction depending on gender differences].
OBJECTIVE
To evaluate gender effects on the correlation between cortisol, molecular products of lipid peroxidation (LPO) and carbonylation of proteins in patients with heroin addiction.


METHODS
Authors examined 82 patients, 49 men and 33 women, with heroin addiction. Biochemical and statistical methods were used.


CONCLUSIONS
Gender differences in the carbonylation of proteins were noted. In men, but not in women, the low level of cortisol was associated with an increased content of carbonylated proteins. In women the level of these proteins was lower than in men. Gender did not exert an effect on LPO.
Chelyabinsk Regional Clinical Drug Addiction Treatment Hospital, Chelyabinsk.
M A
MA
Shatyrko
Chelyabinsk Regional Clinical Drug Addiction Treatment Hospital, Chelyabinsk.
B V
BV
Isarovskyi
South Ural State Medical University, Chelyabinsk.
S V
SV
Golodnii
South Ural State Medical University, Chelyabinsk.
D A
DA
Kozochkin
South Ural State Medical University, Chelyabinsk.
V E
VE
Tseilikman