[Interstitial cystitis/bladder pain syndrome (IC/BPS)].
Interstitial cystitis/bladder pain syndrome (BPS) is still an etiologically poorly understood chronic pain syndrome. BPS is a clinical diagnosis. The current treatment modalities are aimed at symptom relief because no cure is possible. Analgesics may be used at any point in treatment but preferably for short-term relief for flares or bladder pain. AUA has issued clinical practice guidelines with a stepwise approach. The first-line therapy begins with self-care and behavior modification. Physical therapy and oral medications such as amitriptyline, PPS, or antihistamines belong to the second-line therapy. Third-line therapy requires cystoscopy and hydrodistension, treatment of Hunner lesions, or intravesical use of e.g. DMSO. Neuromodulation is considered a fourth-line therapy in patients who have failed third-line treatments. Fifth-line therapies consist of intravesical injection of BoNT or oral cyclosporin A. Cystectomy is the sixth-line therapy and the treatment of last resort.
1 Klinik für Gynäkologie, Universitätsspital Zürich.
David A
DA
Scheiner
Daniele
D
Perucchini
Daniel
D
Fink
Cornelia
C
Betschart
D000328:Adult; D003131:Combined Modality Therapy; D018856:Cystitis, Interstitial / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D005260:Female; D015438:Health Behavior; D006801:Humans; D010147:Pain Measurement; D010353:Patient Education as Topic; D013577:Syndrome; D016896:Treatment Outcome
Bladder Pain Syndrome; Interstitielle Zystitis; bladder pain syndrome; cystite interstitielle; interstitial cystitis; syndrome de la vessie douloureuse