The influence of intraocular pressure and air jet pressure on corneal contactless tonometry tests.
The air puff is a dynamic contactless tonometer test used in ophthalmology clinical practice to assess the biomechanical properties of the human cornea and the intraocular pressure due to the filling fluids of the eye. The test is controversial, since the dynamic response of the cornea is governed by the interaction of several factors which cannot be discerned within a single measurement. In this study we describe a numerical model of the air puff tests, and perform a parametric analysis on the major action parameters (jet pressure and intraocular pressure) to assess their relevance on the mechanical response of a patient-specific cornea. The particular cornea considered here has been treated with laser reprofiling to correct myopia, and the parametric study has been conducted on both the preoperative and postoperative geometries. The material properties of the cornea have been obtained by means of an identification procedure that compares the static biomechanical response of preoperative and postoperative corneas under the physiological IOP. The parametric study on the intraocular pressure suggests that the displacement of the cornea׳s apex can be a reliable indicator for tonometry, and the one on the air jet pressure predicts the outcomes of two or more distinct measurements on the same cornea, which can be used in inverse procedures to estimate the material properties of the tissue.
Mathematics Department, Politecnico di Milano, Piazza Leonardo Da Vinci 32, 20133, Italy. Electronic address: irene.simonini@polimi.it.
Irene
I
Simonini
Civil and Environmental Engineering Department, Politecnico di Milano, Piazza Leonardo Da Vinci 32, 20133, Italy. Electronic address: anna.pandolfi@polimi.it.
Anna
A
Pandolfi
D000399:Air Pressure; D001696:Biomechanical Phenomena; D003315:Cornea / Q000502:physiology*; D006801:Humans; D007429:Intraocular Pressure; D008954:Models, Biological; D014065:Tonometry, Ocular
Air jet pressure; Air puff test; Human cornea; Intraocular pressure; Numerical simulations; Patient-specific models