Renal donors with prostate cancer, no longer a reason to decline.
OBJECTIVE
To fully assess the true risk of prostate cancer transmission in during renal transplantation.


METHODS
A full review of all existing literature relevant to the topic.


RESULTS
There has not been a single documented case of transmission of prostate cancer during renal transplant. Prostate cancer in deceased organ donors has an incidence estimated between 3% and 18.5% and over 100 transplants have been performed using organs from donor with proven prostate cancer without issue.


CONCLUSIONS
Transmission of prostate cancer through kidney transplantation seems very unlikely. The risks of remaining on the waiting list are outweighed by a transmission risk and the potential benefit makes the case to have clear guidelines about donor prostate malignancy when accepting potential organs.
Imperial College Healthcare NHS Trust, West London Renal and Transplant Centre, London, United Kingdom. Electronic address: sham.dholakia@nhs.net.
S
S
Dholakia
Imperial College Healthcare NHS Trust, West London Renal and Transplant Centre, London, United Kingdom.
R
R
Johns
Imperial College Healthcare NHS Trust, West London Renal and Transplant Centre, London, United Kingdom.
L
L
Muirhead
Imperial College Healthcare NHS Trust, West London Renal and Transplant Centre, London, United Kingdom.
V
V
Papalois
Imperial College Healthcare NHS Trust, West London Renal and Transplant Centre, London, United Kingdom.
J
J
Crane
D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D011471:Prostatic Neoplasms; D009927:Tissue and Organ Procurement