Future Perspectives of Radionanomedicine Using the Novel Micelle-Encapsulation Method for Surface Modification.
The emerging radionanomedicine has multifunctional and theranostic purposes. For these purposes, radionanomedicine should achieve the efficient and specific delivery of therapeutic agents by multifunctional characteristics, using low amounts of nanomaterials in vivo. Recent research on radiolabeled micelle-encapsulated nanomaterials has been made on the their efficacy and safety using a one-step surface modification method (Jeong's method). This one-step multifunctional approach to the nanoparticle can be the important challenge in producing effective nanoplatforms for cancer imaging and therapy.
Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.
Yun-Sang
YS
Lee
Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.
Yong-Il
YI
Kim
Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea ; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea ; Department of Nuclear Medicine, Seoul National University Hospital, 101, Daehak-ro, Jongno-gu Seoul, 110-744 Republic of Korea.
Dong Soo
DS
Lee
Nano-materials; Nanomedicine; Radioisotope; Radionanomedicine; Surface-modification