hERG potassium channel inhibition by ivabradine requires channel gating.
School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Dario
D
Melgari
Department of Cardiovascular Sciences, Cardiology Group, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.
Kieran E
KE
Brack
School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Yihong
Y
Zhang
School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Aziza
A
El Harchi
Department of Cell Physiology and Pharmacology, Maurice Shock Medical Sciences Building, University Road, PO Box 138, Leicester LE1 9HN, UK.
John S
JS
Mitcheson
School of Biochemistry, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Christopher E
CE
Dempsey
Department of Cardiovascular Sciences, Cardiology Group, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK; NIHR Leicester Cardiovascular Biomedical Research Unit, Leicester LE3 9QP, UK.
G André
GA
Ng
School of Physiology & Pharmacology, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK. Electronic address: jules.hancox@bristol.ac.uk.
Jules C
JC
Hancox
D000818:Animals; D001552:Benzazepines / Q000494:pharmacology*; D051638:Ether-A-Go-Go Potassium Channels / Q000037:antagonists & inhibitors*; D006801:Humans; D064428:Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels / Q000037:antagonists & inhibitors*; D032383:Myocytes, Cardiac / Q000502:physiology*; D026902:Potassium Channel Blockers / Q000494:pharmacology*
D001552:Benzazepines; D051638:Ether-A-Go-Go Potassium Channels; D064428:Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; D026902:Potassium Channel Blockers