Neural correlates of psychological resilience and their relation to life satisfaction in a sample of healthy young adults.
Psychological resilience refers to the ability to thrive in the face of risk and adversity, which is crucial for individuals' mental and physical health. However, its precise neural correlates are still largely unknown. Here we used resting-state functional magnetic resonance imaging (rs-fMRI) to identify the brain regions underlying this construct by correlating individuals' psychological resilience scores with the regional homogeneity (ReHo) and then examined how these resilience-related regions predicted life satisfaction in a sample of healthy young adults. We found that the ReHo in the bilateral insula, right dorsal anterior cingulate cortex (dACC) and right rostral ACC (rACC) negatively predicted individual differences in psychological resilience, revealing the critical role of the salience network (SN) in psychological resilience. Crucially, the ReHo in the dACC within the SN mediated the effects of psychological resilience on life satisfaction. In summary, these findings suggest that spontaneous activity of the human brain reflect the efficiency of psychological resilience and highlight the dACC within the SN as a neural substrate linking psychological resilience and life satisfaction.
State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing, China. Electronic address: kongfeng87@126.com.
Feng
F
Kong
State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing, China.
Xu
X
Wang
School of Psychology, Beijing Normal University, Beijing, China.
Siyuan
S
Hu
School of Psychology, Beijing Normal University, Beijing, China. Electronic address: liujia@bnu.edu.cn.
Jia
J
Liu
D000328:Adult; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D005260:Female; D006179:Gyrus Cinguli / Q000502:physiology*; D006801:Humans; D007206:Individuality; D008279:Magnetic Resonance Imaging; D008297:Male; D010549:Personal Satisfaction; D055500:Resilience, Psychological; D055815:Young Adult
Anterior cingulate cortex; Life satisfaction; Resilience; Spontaneous brain activity