Antifungal activity of nano and micro charcoal particle polymers against Paecilomyces variotii, Trichoderma virens and Chaetomium globosum.
This study investigates the antifungal activity of a polymer integrated with nano-porous charcoal particles against Paecilomyces variotii, Chaetomium globosum, Trichoderma virens, which are all filamentous fungi. The charcoal polymers were prepared by combining charcoal powders with plastic resin under a vacuum to form charcoal particle protrusions on the polymer surface. The mycelial growth of P. variotii and T. virens exhibited a reduction of 10 and 30%, respectively, after the conidia were pre-treated with charcoal polymers, and in particular, no mycelial growth was found in C. globosum during 5 days of culture. The adsorption of Ca(2+) into charcoal was suggested to inhibit growth due to the reduction in the flux of calcium ions (Ca(2+)) into the hyphae. In 5 h, about 15 mM of Ca(2+) were removed from CaCl2 solution with 0.2 g/mL of polymers, and the nano-sized pores of the charcoals on the polymer were responsible for the Ca(2+) adsorption.
Department of Energy and Biotechnology, Myongji University, Yongin 449-728, Republic of Korea.
Hee Jin
HJ
Yang
Department of Energy and Biotechnology, Myongji University, Yongin 449-728, Republic of Korea.
Yun Jeong
YJ
Cha
Department of Energy and Biotechnology, Myongji University, Yongin 449-728, Republic of Korea.
Hern
H
Kim
Department of Energy and Biotechnology, Myongji University, Yongin 449-728, Republic of Korea; Department of Food and Nutrition, Myongji University, Yongin 449-728, Republic of Korea. Electronic address: sschoi@mju.ac.kr.
Shin Sik
SS
Choi
D000327:Adsorption; D000935:Antifungal Agents / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism; D002597:Chaetomium / Q000187:drug effects*; D002606:Charcoal / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D025282:Mycelium / Q000187:drug effects / Q000254:growth & development; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010143:Paecilomyces / Q000187:drug effects*; D010316:Particle Size; D010969:Plastics / Q000494:pharmacology; D011108:Polymers / Q000494:pharmacology*; D016062:Porosity; D013172:Spores, Fungal / Q000187:drug effects / Q000254:growth & development; D014242:Trichoderma / Q000187:drug effects*
D000935:Antifungal Agents; D010969:Plastics; D011108:Polymers; D002606:Charcoal; D002118:Calcium