Perioperative Treatment of Patients with Rheumatoid Arthritis.
Rheumatoid arthritis is an autoimmune disease mediated by a widespread chronic systematic inflammatory process that causes joint deterioration, which leads to pain, disability, and poor quality of life. The increased use of disease-modifying antirheumatic drugs has been shown to markedly slow disease progression, which has translated into a decrease in the need for orthopaedic intervention in this population. However, a substantial percentage of patients with the disease fail optimal pharmacologic treatment and still require surgical intervention. A thorough understanding of medical considerations in these patients and improved knowledge of the medical complications caused by the disease process and the pharmacologic therapy used to treat it may lead to improved preoperative planning and medical clearance, which may ultimately improve the overall postoperative outcome.
Khaled J
KJ
Saleh
Alexander J
AJ
Kurdi
Mouhanad M
MM
El-Othmani
Benjamin A
BA
Voss
Tony H
TH
Tzeng
Jasmine
J
Saleh
Joseph M
JM
Lane
William M
WM
Mihalko
D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D019637:Orthopedic Procedures / Q000379:methods*; D057234:Preoperative Period; D016896:Treatment Outcome
D018501:Antirheumatic Agents
disease-modifying antirheumatic drugs; preoperative clearance; rheumatoid arthritis