Personalised Medicine Possible With Real-Time Integration of Genomic and Clinical Data To Inform Clinical Decision-Making.
Despite widespread use of genomic sequencing in research, there are gaps in our understanding of the performance and provision of genomic sequencing in clinical practice. The Melbourne Genomics Health Alliance (the Alliance), has been established to determine the feasibility, performance and impact of using genomic sequencing as a diagnostic tool. The Alliance has partnered with BioGrid Australia to enable the linkage of genomic sequencing, clinical treatment and outcome data for this project. This integrated dataset of genetic, clinical and patient sourced information will be used by the Alliance to evaluate the potential diagnostic value of genomic sequencing in routine clinical practice. This project will allow the Alliance to provide recommendations to facilitate the integration of genomic sequencing into clinical practice to enable personalised disease treatment.
BioGrid Australia, Melbourne, VIC, AUSTRALIA.
Fernando
F
Martin-Sanchez
BioGrid Australia, Melbourne, VIC, AUSTRALIA.
Maureen
M
Turner
BioGrid Australia, Melbourne, VIC, AUSTRALIA.
Alice
A
Johnstone
BioGrid Australia, Melbourne, VIC, AUSTRALIA.
Leon
L
Heffer
BioGrid Australia, Melbourne, VIC, AUSTRALIA.
Naomi
N
Rafael
Melbourne Genomics Health Alliance, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, AUSTRALIA.
Tim
T
Bakker
Melbourne Genomics Health Alliance, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, AUSTRALIA.
Natalie
N
Thorne
Melbourne Genomics Health Alliance, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, AUSTRALIA.
Ivan
I
Macciocca
Melbourne Genomics Health Alliance, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, AUSTRALIA.
Clara
C
Gaff
D003628:Database Management Systems / Q000458:organization & administration*; D030541:Databases, Genetic; D020000:Decision Support Systems, Clinical; D057286:Electronic Health Records / Q000458:organization & administration*; D005240:Feasibility Studies; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D008498:Medical Record Linkage / Q000379:methods; D057285:Precision Medicine / Q000379:methods*; D018511:Systems Integration