A Case of Leukemoid Reaction in Pancreatic Ductal Adenocarcinoma.
Leukemoid reaction is defined as leukocytosis exceeding 50,000 cells/mm(3). When it occurs in a patient with a malignancy, secondary causes such as infections, drugs, hematologic diseases and hemorrhage need to be ruled out. After excluding such causes, paraneoplastic leukemoid reaction can be considered as a diagnosis of exclusion. Paraneoplastic leukemoid reactions have been described in association with lung, gastrointestinal, genitourinary and head and neck cancers. However, pancreatic cancer with leukemoid reaction has been rarely reported. We diagnosed a case of a 55-year-old Korean woman with extreme leukocytosis associated with advanced pancreatic cancer.
Departments of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
Kyong Hee
KH
Hong
Departments of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
Jun Kyu
JK
Lee
Departments of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
Seung Joo
SJ
Byun
Departments of Laboratory Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
Jae Woo
JW
Jung
Departments of Surgery, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
In Woong
IW
Han
Departments of Radiology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
Jin Hee
JH
Jung
Departments of Pathology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
Eo Jin
EJ
Kim
D021441:Carcinoma, Pancreatic Ductal / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000166:cytology; D007964:Leukocytosis / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000150:complications / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
Leukemoid reaction; Pancreatic neoplasms; Paraneoplastic syndromes