Simultaneous Determination of 10 Ultratrace Elements in Infant Formula, Adult Nutritionals, and Milk Products by ICP/MS After Pressure Digestion: Single-Laboratory Validation.
A single-laboratory validation (SLV) is presented for the simultaneous determination of 10 ultratrace elements (UTEs) including aluminum (Al), arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), mercury (Hg), molybdenum (Mo), lead (Pb), selenium (Se), and tin (Sn) in infant formulas, adult nutritionals, and milk based products by inductively coupled plasma (ICP)/MS after acidic pressure digestion. This robust and routine multielemental method is based on several official methods with modifications of sample preparation using either microwave digestion or high pressure ashing and of analytical conditions using ICP/MS with collision cell technology. This SLV fulfills AOAC method performance criteria in terms of linearity, specificity, sensitivity, precision, and accuracy and fully answers most international regulation limits for trace contaminants and/or recommended nutrient levels established for 10 UTEs in targeted matrixes.
Nestlé Research Center, Analytical Sciences Pillar/Minerals and Imaging Group, Vers-chez-les-Blanc, 1000 Lausanne 26, Switzerland.
Stephane
S
Dubascoux
Marine
M
Nicolas
Celine Fragniere
CF
Rime
Janique Richoz
JR
Payot
Eric
E
Poitevin
D000328:Adult; D003611:Dairy Products / Q000032:analysis*; D006801:Humans; D041943:Infant Formula / Q000737:chemistry*; D007753:Laboratories; D013058:Mass Spectrometry / Q000379:methods*; D011312:Pressure; D013054:Spectrophotometry, Atomic / Q000379:methods*; D014131:Trace Elements / Q000032:analysis*
D014131:Trace Elements