The Role of Multidrug Resistance Efflux Pumps in Cancer: Revisiting a JNCI Publication Exploring Expression of the MDR1 (P-glycoprotein) Gene.
Laboratory of Cell Biology (MMG) and Laboratory of Molecular Biology (IHP), Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD. mgottesman@nih.gov.
Michael M
MM
Gottesman
Laboratory of Cell Biology (MMG) and Laboratory of Molecular Biology (IHP), Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Ira H
IH
Pastan
D018435:ATP Binding Cassette Transporter, Subfamily B / Q000235:genetics*; D002986:Clinical Trials as Topic; D015986:Confounding Factors, Epidemiologic; D019008:Drug Resistance, Neoplasm / Q000235:genetics*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D054547:National Cancer Institute (U.S.); D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism*; D010506:Periodicals as Topic; D012107:Research Design; D058028:Research Report; D014481:United States
C513055:ABCB1 protein, human; D018435:ATP Binding Cassette Transporter, Subfamily B