Transcatheter mitral valve replacement: design implications, potential pitfalls and outcomes assessment.
Transcatheter mitral valve replacement (TMVR) is an emerging new treatment option in patients with advanced mitral valve disease deemed a high or prohibitive risk for surgery. Designing an ideal TMVR device requires a detailed understanding of different mitral valve pathologies and the complex, dynamic anatomy and physiology of the mitral apparatus. This review aims to critically evaluate design implications in TMVR in the context of mitral valve disease, imaging prerequisites, procedural approaches, potential complications, and outcomes assessment.
From the *Section of Cardiothoracic Surgery, Westchester Medical Center, New York Medical College, Valhalla, NY; †Division of Cardiothoracic Surgery, ‡Division of Cardiology, New York Presbyterian Hospital, College of Physicians and Surgeons of Columbia University, New York, NY; §Department of Cardiothoracic Surgery, St. Thomas' Hospital, London, United Kingdom; and ‖Division of Cardiovascular Surgery, University of Pennsylvania Medical Center, Philadelphia, PA.
Gilbert H L
GH
Tang
Isaac
I
George
Rebecca T
RT
Hahn
Vinayak
V
Bapat
Wilson Y
WY
Szeto
Susheel K
SK
Kodali
D006328:Cardiac Catheterization / Q000009:adverse effects / Q000379:methods*; D003952:Diagnostic Imaging / Q000379:methods; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D008946:Mitral Valve Stenosis / Q000601:surgery*; D011474:Prosthesis Design; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000601:surgery