Umbilical Cord Coiling and Zygosity: Is there a Link?
BACKGROUND
The aim of this study was to analyze abnormalities of umbilical coiling index (UCI) in twin gestation to test whether the coiling is genetically influenced by zygosity.


METHODS
Data retrieved comprised gestational age (GA), chorionicity, fetal gender, and UCI.


RESULTS
The mean UCI of hypercoiled cords in monochorionic placentas was 0.55 coils/cm and 0.49 coils/cm in dichorionic placentas with discordant fetal gender (P = 0.2629).


CONCLUSIONS
In conclusion, no significant statistical difference between UCI in monochorionic and dichorionic twin placentas with discordant fetal gender was identified, suggesting that zygosity does not play a role in umbilical coiling induction.
a Department of Histopathology , Sheffield Children's Hospital , Western Bank , United Kingdom.
André Joannou
AJ
Coetzee
b Department of Pathology and Immunology , Texas Childrens Hospital , Houston , Texas , USA.
Eumenia
E
Castro
a Department of Histopathology , Sheffield Children's Hospital , Western Bank , United Kingdom.
Luiz Cesar
LC
Peres
D005260:Female; D006801:Humans; D011247:Pregnancy; D059285:Pregnancy, Twin; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic; D014470:Umbilical Cord / Q000002:abnormalities* / Q000473:pathology
chorionicity; hypercoiling; hypocoiling; twin placenta; umbilical cord coiling index; zygosity