Predisposing Factors for Spontaneous Closure of Congenital Portosystemic Shunts.
In a review of 382 cases of congenital portosystemic shunt, we found that presentation with neonatal cholestasis strongly predicts spontaneous closure of intrahepatic shunts (OR 8.3, 95% CI 3.4-20.2). Spontaneous closure before the 24th month of age is more likely for distal or multiple shunts, but rare for patent ductus venosus.
Pediatric Gastroenterology, Hepatology, and Nutrition, CHU Sainte-Justine, Université de Montréal, Montreal, Québec, Canada. Electronic address: m.paganelli@umontreal.ca.
Massimiliano
M
Paganelli
Pediatric Radiology, Hospital de Pediatria "Garrahan", Buenos Aires, Argentina.
José E
JE
Lipsich
Pediatric Gastroenterology, Hepatology, and Liver Transplantation, ISMETT, Palermo, Italy.
Marco
M
Sciveres
Pediatric Gastroenterology, Hepatology, and Nutrition, CHU Sainte-Justine, Université de Montréal, Montreal, Québec, Canada.
Fernando
F
Alvarez
D015984:Causality; D002675:Child, Preschool; D002779:Cholestasis / Q000000981:diagnostic imaging; D005260:Female; D005500:Follow-Up Studies; D005762:Gastroenterology / Q000379:methods; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011169:Portal Vein / Q000002:abnormalities* / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D016896:Treatment Outcome; D014463:Ultrasonography; D054079:Vascular Malformations / Q000000981:diagnostic imaging / Q000628:therapy*