BNCT treatment planning for superficial and deep-seated tumors: Experience from clinical trial of recurrent head and neck cancer at THOR.
Under the collaboration between National Tsing Hua University and Taipei Veterans General Hospital, clinical trial of recurrent head-and-neck cancer by Boron neutron capture therapy at Tsing Hua open-pool reactor started on August 11, 2010. Up to January 2014, 17 patients were treated. Based on the treatment planning experiences of clinical trials using in-house designed THORplan, different setups should be used for superficial and deep-seated tumors. Superficial tumor treatment gains benefits from the use of patient collimator, while direct irradiation is a better choice for deep-seated tumor.
Institute of Nuclear Engineering and Science, National Tsing Hua University, Hsinchu, Taiwan, ROC. Electronic address: ywhliu@gmail.com.
Yen-Wan Hsueh
YW
Liu
Institute of Nuclear Engineering and Science, National Tsing Hua University, Hsinchu, Taiwan, ROC.
Chih-Ting
CT
Chang
Institute of Nuclear Engineering and Science, National Tsing Hua University, Hsinchu, Taiwan, ROC.
Lan-Yun
LY
Yeh
Department of Oncology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Ling-Wei
LW
Wang
Institute of Nuclear Engineering and Science, National Tsing Hua University, Hsinchu, Taiwan, ROC.
Tzung-Yi
TY
Lin
D016754:Boron Neutron Capture Therapy; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*
Boron neutron capture therapy; Head and neck cancer; Treatment planning