Response validity of Persian version of P-QOL questionnaire in patients with prolapse.
OBJECTIVE
Pelvic organ prolapse (POP) refers to drop of any pelvic organs into or outside of the vaginal canal or anus. This is a disabling condition that results in limitations in all aspects of women's lives, especially quality of life. The evaluation of quality of life in women with POP requires the use of a valid and reliable measure. An important aspect of validity is responsiveness. The aim of current study is to evaluate the responsiveness of P-QOL questionnaire in patients with prolapse.


METHODS
Women with confirmed diagnosed POP by gynecologist who were scheduled to undergo POP's treatment enrolled in the study. Quality of life as an outcome measure was evaluated before and six month after treatment besides assessing of physical index of treatment's effect (pelvic organ prolapse quantification; POP-Q). Responsiveness was evaluated using calculation of standardized response mean (SRM) and effect size (ES).


RESULTS
Fifty women were evaluated in current study. Mean age was 43.5±11.8 years old. The range of Cronbach's alpha was between 0.60 and 0.89 for all domains of P-QOL. The range of SRM for all domains was between 0.60 and 0.88. The range of ES was between 0.54 and 0.96. Score of all domains of P-QOL was statistically different between pre and post-treatment (P<0.0001).


CONCLUSIONS
The findings of current study showed the P-QOL questionnaire has a good responsiveness in Persian language and could use to assess the impact of interventions on quality of life in patients with prolapse.
Health System Research Committee, Treatment Affairs of Vice Chancellery, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: negarmorovat@gmail.com.
Negar
N
Morovatdar
Department of Obstetrics and Gynecology, Akabr-Abadi Hospital, Iran University of Medical Sciences, Tehran, Iran. Electronic address: haghighi.l@iums.ac.ir.
Ladan
L
Hghighi
Department of Obstetrics and Gynecology, Akabr-Abadi Hospital, Iran University of Medical Sciences, Tehran, Iran. Electronic address: zahranaj@yahoo.com.
Zahra
Z
Najmi
Department of Community Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address: Ati_hashemi@yahoo.com.
Atiyeh
A
Hashemi
Department of Community Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address: mnojomi@iums.ac.ir.
Marzieh
M
Nojomi
D000328:Adult; D005260:Female; D006801:Humans; D007492:Iran; D007802:Language; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000523:psychology* / Q000628:therapy; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D013223:Statistics as Topic; D011795:Surveys and Questionnaires
P-QOL; Prolapse; Quality of life; Responsiveness