SnapShot: Interactions between B Cells and T Cells.
Dynamic interactions between B and T cells underpin the development of adaptive humoral immune responses to infections and vaccines. Recent advances in the molecular and spatiotemporal control of these interactions during primary responses have contributed greatly to elucidating the molecular pathogenesis of numerous immunodeficiency and autoimmune diseases. The next challenge is to determine how and where memory B and T cells interact during secondary responses to facilitate the rapid and robust response that characterizes anamnestic immunity.
Immunology Division, Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, 2010 UNSW, Australia.
Stuart G
SG
Tangye
Immunology Division, Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, 2010 UNSW, Australia.
Robert
R
Brink
Immunology Division, Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, 2010 UNSW, Australia.
Christopher C
CC
Goodnow
Immunology Division, Garvan Institute of Medical Research, Darlinghurst NSW 2010, Australia; St Vincent's Clinical School, 2010 UNSW, Australia.
Tri Giang
TG
Phan
D000818:Animals; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000166:cytology / Q000378:metabolism*; D002450:Cell Communication; D006801:Humans; D007156:Immunologic Memory; D013601:T-Lymphocytes / Q000166:cytology / Q000378:metabolism*; D050378:T-Lymphocytes, Regulatory / Q000166:cytology