[Metabolic syndrome and risk of recurrence after catheter ablation of long-standing persistent atrial fibrillation].
OBJECTIVE
This study sought to explore the impact of metabolic syndrome (MS) on the risk of recurrence after catheter ablation of long-standing persistent atrial fibrillation (AF).


METHODS
Totally 248 patients [197 male, (56±12)years] with persistent AF and catheter ablation were included. Long-standing persistent AF was defined based on the duration (more than one year).


RESULTS
Among the 248 patients, 96 (38.7%) patients had MS, 130 (52.4%) patients had long-standing persistent AF. After 91-1222 (404±303) days follow-up, 119 (47.9%) had recurrence. The recurrence rate was significantly higher in the MS group than that in the non-MS group (58.3% vs 41.4%, P = 0.017). The proportion of MS was similar between the long-standing persistent AF group and the non-long-standing persistent AF group (36.9% vs 40.7%, P = 0.544). Subjects with MS had higher recurrence rate than those without MS in non-long-standing AF group (56.3% vs 32.9%, P = 0.033), but not in long-standing AF group (60.4% vs 48.8%, P = 0.177). In multivariate analysis, MS (hazard ratio 1.98, 95% CI 1.04-3.76, P = 0.036) and AF history duration (hazard ratio 1.04, 95% CI 1.01-1.07, P = 0.004) were independent risk factors for recurrence after catheter ablation of AF. Long-standing persistent AF was not an independent risk factor of recurrence.


CONCLUSIONS
MS was natively associated with the success rate of catheter ablation of AF in patients with non-long-standing persistent AF, but not in patients with long-standing persistent AF.
Ribo
R
Tang
Jianzeng
J
Dong
Meisheng
M
Shang
Ronghui
R
Yu
Deyong
D
Long
Xin
X
Du
Junping
J
Kang
Jiahui
J
Wu
Rong
R
Bai
Caihua
C
Sang
Man
M
Ning
Chenxi
C
Jiang
Songnan
S
Li
Yan
Y
Yao
Songnan
S
Wen
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China; Email: chshma@vip.sina.com.
Changsheng
C
Ma
D001281:Atrial Fibrillation / Q000150:complications* / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000175:diagnosis; D015999:Multivariate Analysis; D012008:Recurrence; D012086:Reoperation; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome