Oxcarbazepine induced toxic epidermal necrolysis - a rare case report.
Carbamazepine, is well known to cause Stevens-Johnson syndrome and toxic epidermal necrolysis(TEN). Oxcarbazepine, a 10-keto analog of carbamazepine, is an anticholinergic, anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy. Its efficacy is similar to carbamazepine but allergic reactions and enzyme induction is low. We describe a case of oxcarbazepine induced TEN, who presented with erythematous ulcerative maculopapular rash.
Department of Medicine, Military Hospital, Palampur, Himachal Pradesh, India.
Vivek S
VS
Guleria
Department of Medicine, Military Hospital, Palampur, Himachal Pradesh, India.
Chetan
C
Sharda
Department of Medicine, Military Hospital, Palampur, Himachal Pradesh, India.
Tanuja
T
Rana
Department of Medicine, Military Hospital, Palampur, Himachal Pradesh, India.
A K
AK
Sood
D000927:Anticonvulsants / Q000009:adverse effects*; D002220:Carbamazepine / Q000009:adverse effects / Q000031:analogs & derivatives*; D004890:Erythema / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D000078330:Oxcarbazepine; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000473:pathology
D000927:Anticonvulsants; D002220:Carbamazepine; D000078330:Oxcarbazepine
Carbamazepine; Stevens–Johnson syndrome; oxcarbazepine; toxic epidermal necrolysis