INFLAMMATORY MARKERS ASSOCIATED WITH TRAUMA AND INFECTION IN RED-TAILED HAWKS (BUTEO JAMAICENSIS) IN THE USA.
Changes in inflammatory marker concentrations or activity can be used to monitor health and disease condition of domestic animals but have not been applied with the same frequency to wildlife. We measured concentrations or activity of six inflammatory markers (ceruloplasmin, haptoglobin, mannan-binding lectin-dependent complement [MBL/complement], unsaturated iron-binding capacity (UIBC) and total iron-binding capacity (TIBC), and plasma iron) in apparently healthy and sick or injured Red-tailed Hawks (Buteo jamaicensis). Haptoglobin and ceruloplasmin activities were consistently elevated in sick or injured hawks (2.1 and 2.5 times higher, respectively), and plasma iron concentrations decreased (0.46 times lower), relative to those of healthy birds. There were no differences between healthy and unhealthy hawks in TIBC and UIBC concentrations or MBL/complement activity. Therefore, haptoglobin, ceruloplasmin, and plasma iron would be useful inclusions in a panel of inflammatory markers for monitoring health in raptors.
1  Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 1 Shields Ave., Davis, California 95616, USA.
Kelly A
KA
Lee
1  Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 1 Shields Ave., Davis, California 95616, USA.
Valerie S
VS
Goetting
1  Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, 1 Shields Ave., Davis, California 95616, USA.
Lisa A
LA
Tell
D000818:Animals; D001424:Bacterial Infections / Q000662:veterinary*; D015415:Biomarkers; D001715:Bird Diseases / Q000097:blood / Q000378:metabolism*; D046428:Hawks; D007249:Inflammation / Q000097:blood / Q000378:metabolism / Q000662:veterinary*; D014947:Wounds and Injuries / Q000097:blood / Q000662:veterinary*
D015415:Biomarkers
Acute phase; Red-tailed Hawks; ceruloplasmin; haptoglobin, infection; iron-binding capacity; mannan binding; trauma