Interplay between Static and Dynamic Energy Transfer in Biofunctional Upconversion Nanoplatforms.
Clarification of the energy-transfer (ET) mechanism is of vital importance for constructing efficient upconversion nanoplatforms for biological/biomedical applications. Yet, most strategies of optimizing these nanoplatforms were casually based on a dynamic ET assumption. In this work, we have modeled quantitatively the shell-thickness-dependent interplay between dynamic and static ET in nanosystems and validated the model in a typical biofunctional upconversion nanoplatform composed of NaYF4:Er, Yb/NaYF4 upconversion nanoparticles (UCNPs), and energy-acceptor photosensitizing molecule Rose Bengal (RB). It was determined that with a proper thickness shell, the energy transferred via dynamic ET as well as static ET in this case could be significantly improved by ∼4 and ∼9 fold, respectively, compared with the total energy transferred from bare core UCNPs. Our results shall form the bedrock in designing highly efficient ET-based biofunctional nanoplatforms.
†Centre for Advanced Optoelectronic Functional Materials Research, Key Laboratory for UV Light-Emitting Materials and Technology of the Ministry of Education, Northeast Normal University, Changchun 130024, People's Republic of China.|#Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1105 AZ Amsterdam, The Netherlands.
Yadan
Y
Ding
§State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, People's Republic of China.
Fei
F
Wu
§State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, People's Republic of China.
Youlin
Y
Zhang
§State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, People's Republic of China.
Xiaomin
X
Liu
Elinore M L D
EM
de Jong
Tom
T
Gregorkiewicz
†Centre for Advanced Optoelectronic Functional Materials Research, Key Laboratory for UV Light-Emitting Materials and Technology of the Ministry of Education, Northeast Normal University, Changchun 130024, People's Republic of China.
Xia
X
Hong
†Centre for Advanced Optoelectronic Functional Materials Research, Key Laboratory for UV Light-Emitting Materials and Technology of the Ministry of Education, Northeast Normal University, Changchun 130024, People's Republic of China.
Yichun
Y
Liu
#Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1105 AZ Amsterdam, The Netherlands.
Maurice C G
MC
Aalders
Wybren Jan
WJ
Buma
§State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, People's Republic of China.
Hong
H
Zhang
D004735:Energy Transfer / Q000502:physiology*; D053768:Metal Nanoparticles / Q000737:chemistry*; D056004:Molecular Dynamics Simulation
Er3+/NaYF4; Förster resonant energy transfer; NaYF4:Yb3+; inner filter effect; optimal shell thickness; quantitative analysis; reabsorption; upconversion