Neonatal Sweet's Syndrome Associated with Rectovestibular Fistula with Normal Anus.
Sweet's syndrome, characterized by fever and a painful erythematous rash with a dermal neutrophilic infiltrate, develops primarily due to paraneoplastic phenomena in adults. Sweet's syndrome is very rare in neonates. We report a Japanese female neonate (age <2 months), who developed Sweet's syndrome with episodes of perineal infection in association with congenital rectovestibular fistula with normal anus. Sweet's syndrome was diagnosed basing on clinical features and histopathology of biopsied skin tissues. Rectovestibular fistula was confirmed after the signs of inflammation subsided and the rash disappeared. In the literature, we found another case of neonatal Sweet's syndrome associated with rectovestibular fistula in a Japanese female neonate. The perineal region should be screened for anomalies following diagnosis of Sweet's syndrome in neonates.
Division of Pediatrics, Uji-Tokushukai Medical Center , Uji, Kyoto, Japan.
Jun
J
Shinozuka
Division of Pediatric Surgery, Uji-Tokushukai Medical Center , Uji, Kyoto, Japan.
Hideki
H
Tomiyama
Division of Pediatrics, Uji-Tokushukai Medical Center , Uji, Kyoto, Japan.
Shin-Ichiro
S
Tanaka
Division of Pediatrics, Uji-Tokushukai Medical Center , Uji, Kyoto, Japan.
Junko
J
Tahara
Division of Pediatrics, Uji-Tokushukai Medical Center , Uji, Kyoto, Japan.
Hitoshi
H
Awaguni
Division of Pediatrics, Uji-Tokushukai Medical Center , Uji, Kyoto, Japan.
Shigeru
S
Makino
Division of Pediatrics, Uji-Tokushukai Medical Center , Uji, Kyoto, Japan.
Rikken
R
Maruyama
Division of Laboratory Medicine, Uji-Tokushukai Medical Center , Uji, Kyoto, Japan.
Shinsaku
S
Imashuku
Sweet’s syndrome; neonate; rectovestibular fistula