Working stiff: how obesity boosts cancer risk.
Obesity promotes breast cancer by enhancing the stiffness of breast adipose tissue through changes in the extracellular matrix (Seo et al., this issue).
Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA.
Lisa M
LM
Arendt
Developmental, Molecular, and Chemical Biology Department, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA. Molecular Oncology Research Institute, Tufts Medical Center, Boston, MA 02111, USA. Raymond and Beverly Sackler Convergence Laboratory, Tufts University School of Medicine, Boston, MA 02111, USA. charlotte.kuperwasser@tufts.edu.
Charlotte
C
Kuperwasser
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D001943:Breast Neoplasms / Q000209:etiology* / Q000378:metabolism*; D005109:Extracellular Matrix / Q000378:metabolism*; D005260:Female; D006801:Humans; D009765:Obesity / Q000378:metabolism*