THE CONSUMPTION OF ACAI PULP CHANGES THE CONCENTRATIONS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 AND EPIDERMAL GROWTH FACTOR (EGF) IN APPARENTLY HEALTHY WOMEN.
BACKGROUND
obesity, characterized by adiposity excess, is associated with endothelial dysfunction and possible inflammatory state with release of cytokines that determine endothelial function and can trigger chronic diseases. The dietary pattern are associated with the synthesis these cytokines. Fruits as the acai, which is rich in flavonoids, have a direct and beneficial effect on the control of this inflammatory process through the exercised antioxidant capacity.


OBJECTIVE
to evaluate the effect of acai pulp consumption on the inflammatory markers, anthropometric measurements, body composition, biochemical and dietary parameters in healthy women.


METHODS
forty women, were divided in 25 eutrophic and 15 with overweight. They intaked 200 g of acai pulp during 4 weeks. Anthropometric measurements, body composition, inflammatory markers, biochemical data, dietary intake and dietary antioxidants capacity were evaluated before and after the intervention.


CONCLUSIONS
after the intervention, there was significant increase of EGF (p = 0.021) and PAI- 1(p = 0.011) in overweight women. Moreover, there was increase in body weight (p = 0.031), body mass index (p = 0.028), percentage of truncal fat (p = 0.003) and triceps skinfold thickness (p = 0.046) in eutrophic women. However, the skinfold thickness (p = 0.018) and total body fat (p = 0.016) decreased in overweight women. There was reduction of total protein (p = 0.049) due to the globulin reduction (p = 0.005), but the nutritional status was maintained in eutrophic group.


CONCLUSIONS
the intake of 200g acai pulp, modulated the EGF and PAI-1 expression, possibly by modulation of acai on the parameters of body composition, dietary, clinical, biochemical and inflammatory, led to a redistribution and resizing of body fat of the trunk area, and presumably increased visceral fat.
MSc. in Health and Nutrition by Federal University of Ouro Preto, Ouro Preto, Minas Gerais.. izzabeli@ig.com.br.
Izabelle
I
de Sousa Pereira
MSc. in Health and Nutrition by Federal University of Ouro Preto, Ouro Preto, Minas Gerais.. anavolp@gmail.com.
Tereza Cristina
TC
Moreira Cançado Mascarenhas Pontes
MSc. in Health and Nutrition by Federal University of Ouro Preto, Ouro Preto, Minas Gerais.. anavolp@gmail.com.
Renata Adrielle
RA
Lima Vieira
MSc. in Health and Nutrition by Federal University of Ouro Preto, Ouro Preto, Minas Gerais.. anavolp@gmail.com.
Gilce Andrezza
GA
de Freitas Folly
PhD in Biological Science and Postdoctoral researcher in Cardiovascular Physiology Laboratory at Federal University of Ouro Preto, Ouro Preto, Minas Gerais.. anavolp@gmail.com.
Fernanda
F
Cacilda Silva
PhD in Statistics, Department of Statistics, Federal University of Ouro Preto, Ouro Preto.. anavolp@gmail.com.
Fernando Luiz
FL
Pereira de Oliveira
PhD in Biochemistry and Immunology and Adjunct Professor at the Federal University of Ouro Preto, Ouro Preto, Minas Gerais.. anavolp@gmail.com.
Joana
J
Ferreira do Amaral
PhD in Biochemistry and Immunology and Associated Professor at the Federal University of Ouro Preto, Ouro Preto, Minas Gerais.. anavolp@gmail.com.
Renata
R
Nascimento de Freitas
PhD in Science and Technology of Food and Adjunct Professor at Universidade Federal de Ouro Preto, Ouro Preto, MG (Brazil).. anavolp@gmail.com.
Ana Carolina
AC
Pinheiro Volp
D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D015415:Biomarkers; D001823:Body Composition; D004032:Diet; D004815:Epidermal Growth Factor / Q000097:blood*; D065748:Euterpe; D005247:Feeding Behavior; D005260:Female; D005638:Fruit; D064368:Healthy Volunteers; D006801:Humans; D018836:Inflammation Mediators; D009765:Obesity / Q000097:blood / Q000378:metabolism; D050177:Overweight / Q000097:blood / Q000378:metabolism; D017395:Plasminogen Activator Inhibitor 1 / Q000097:blood*; D055815:Young Adult
D015415:Biomarkers; D018836:Inflammation Mediators; D017395:Plasminogen Activator Inhibitor 1; D004815:Epidermal Growth Factor