Prochlorperazine-Induced Hemidystonia Mimicking Acute Stroke.
Prochlorperazine is frequently used in the treatment of refractory nausea and migraines. Known side effects include extrapyramidal symptoms such as akathisia and dystonia. We report a pregnant patient taking prochlorperazine for hyperemesis gravidarum who developed hemidystonia, which triggered an acute code stroke response from prehospital, emergency medicine and neurology providers. We suspect this report to be the first case of prochlorperazine-induced hemidystonia as a stroke mimic.
University of California, San Francisco, Departments of Pharmacy and Emergency Medicine, San Francisco, California.
Zlatan
Z
Coralic
University of California, San Francisco, Department of Neurology, San Francisco, California.
Anthony S
AS
Kim
Kaiser Permanente Medical Center, Department of Emergency Medicine, Sacramento, California ; Kaiser Permanente Division of Research, Oakland, California.
David R
DR
Vinson
D000328:Adult; D004155:Diphenhydramine / Q000627:therapeutic use; D004421:Dystonia / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D004635:Emergency Medicine; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000188:drug therapy*; D007262:Infusions, Intravenous; D011247:Pregnancy; D011346:Prochlorperazine / Q000009:adverse effects* / Q000627:therapeutic use; D011446:Prospective Studies; D020521:Stroke
D004155:Diphenhydramine; D011346:Prochlorperazine