Congenital isolated cleft mitral valve leaflet and apical muscular ventricular septal defect in a Holstein calf.
A 5-week-old Holstein heifer calf presented for emergency treatment of signs referable to gastrointestinal disease and hypovolemic shock. Fluid resuscitation uncovered clinical signs of primary cardiac disease and echocardiography revealed multiple congenital cardiac defects. Malformations included a cleft anterior mitral valve leaflet resembling an isolated cleft mitral valve and an apically-located muscular ventricular septal defect. The echocardiographic and postmortem findings associated with these defects are presented and discussed in this report.
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Columbus, OH 43210, USA. Electronic address: sdepenbrock@gmail.com.
Sarah M
SM
Depenbrock
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Columbus, OH 43210, USA.
Lance C
LC
Visser
Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Columbus, OH 43210, USA.
Rebecca A
RA
Kohnken
Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Columbus, OH 43210, USA.
Duncan S
DS
Russell
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Columbus, OH 43210, USA.
Katharine M
KM
Simpson
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Columbus, OH 43210, USA.
John D
JD
Bonagura
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000151:congenital*; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000473:pathology / Q000662:veterinary*; D006349:Heart Valve Diseases / Q000473:pathology / Q000662:veterinary*; D008943:Mitral Valve / Q000002:abnormalities*; D008944:Mitral Valve Insufficiency / Q000473:pathology / Q000662:veterinary*
Bovine; Cardiac; Heart; Pulmonary hypertension