Near fatal desquamative interstitial pneumonia with bilateral recurrent tension pneumothorax.
Desquamative interstitial pneumonia (DIP) is an uncommon form of interstitial lung disease demonstrating good response to corticosteroid therapy and favorable prognosis. In rare cases, patients with DIP fail to respond to corticosteroid therapy, and may progress to end-stage fibrotic lung disease with respiratory failure. For such patients, well defined treatment regimen does not exist until now. We report a rare case of near fatal DIP with recurrent bilateral tension pneumothorax despite of corticosteroid maintenance therapy. Clinical and radiological findings improved with surgical intervention in addition to combination therapy with prednisolone and clarithromycin. The patient has remained in an improved state and has been receiving prednisolone and clarithromycin for 9 months.
Hanyang University College of Medicine, Seoul, Korea. portrayme@hanmail.net.
Dong Won
DW
Park
Tae Hyung
TH
Kim
Jang Won
JW
Shon
Ho Joo
HJ
Yoon
Sung Soo
SS
Park
Seok Chol
SC
Jeon
Yo Won
YW
Choi
Seung Sam
SS
Paik
Hyuck
H
Kim
D000328:Adult; D001707:Biopsy, Needle; D017291:Clarithromycin / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D016638:Critical Illness / Q000628:therapy; D018450:Disease Progression; D005500:Follow-Up Studies; D030342:Genetic Diseases, Inborn / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D061330:Multidetector Computed Tomography / Q000379:methods; D011030:Pneumothorax / Q000175:diagnosis*; D011239:Prednisolone / Q000008:administration & dosage; D035583:Rare Diseases; D012008:Recurrence; D018570:Risk Assessment; D020775:Thoracic Surgery, Video-Assisted / Q000379:methods; D016896:Treatment Outcome
D011239:Prednisolone; D017291:Clarithromycin