Congenital Malformations Associated With a Single Umbilical Artery in Twin Pregnancies.
A single umbilical artery (SUA) was identified in 1.5% of twin pregnancies. The presence of a SUA in a twin pregnancy was associated with a 50% incidence of fetal anomalies, many of them complex and severe. The embryology and pathophysiological mechanisms associated with a SUA are reviewed. Aneuploidy is relatively common and should be considered, particularly in the presence of associated anomalies. Fetal growth restriction is frequent and preterm delivery is common.
Division of Maternity Services,The Royal Women's Hospital,Melbourne,Victoria,Australia.
Sarah E
SE
Mitchell
Pregnancy Research Centre,The Royal Women's Hospital,Melbourne,Victoria,Australia.
Karen
K
Reidy
Division of Maternity Services,The Royal Women's Hospital,Melbourne,Victoria,Australia.
Fabricio
F
Da Silva Costa
Division of Maternity Services,The Royal Women's Hospital,Melbourne,Victoria,Australia.
Ricardo
R
Palma-Dias
Division of Maternity Services,The Royal Women's Hospital,Melbourne,Victoria,Australia.
Thomas J
TJ
Cade
Division of Maternity Services,The Royal Women's Hospital,Melbourne,Victoria,Australia.
Mark P
MP
Umstad
D000328:Adult; D000013:Congenital Abnormalities / Q000175:diagnosis* / Q000000981:diagnostic imaging; D016208:Databases, Factual; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D059285:Pregnancy, Twin; D047928:Premature Birth / Q000175:diagnosis* / Q000000981:diagnostic imaging; D058529:Single Umbilical Artery / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000002:abnormalities; D055815:Young Adult
fetal anomalies; growth restriction; single umbilical artery; twins