Destabilizing DNA during Rejoining Enhances Fidelity of Repair.
A new study shows that during repair of DNA, the effect of a single-strand annealing protein is to destabilize DNA duplex formation so that annealing only occurs between perfectly matched strands; the protein then clamps the strands together for repair. Read the Research Article.
Freelance Science Writer, Sherborn, Massachusetts, United States of America.
Richard
R
Robinson
D010582:Bacteriophage lambda / Q000235:genetics*; D004260:DNA Repair / Q000502:physiology*; D004277:DNA, Single-Stranded / Q000378:metabolism*; D004279:DNA, Viral / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D012689:Sequence Homology, Nucleic Acid; D014764:Viral Proteins / Q000378:metabolism*
D004277:DNA, Single-Stranded; D004279:DNA, Viral; D004268:DNA-Binding Proteins; D014764:Viral Proteins