Infection Control Programs and Antibiotic Control Programs to Limit Transmission of Multi-Drug Resistant Acinetobacter baumannii Infections: Evolution of Old Problems and New Challenges for Institutes.
BACKGROUND
Acinetobacter baumannii complex (A. baumannii) has been isolated worldwide. The rapid spread of multidrug-resistant A. baumannii complex (MDRAB) in clinical settings has made choosing an appropriate antibiotic to treat these infections and executing contact precautions difficult for clinicians. Although controlling the transmission of MDRAB is a high priority for institutions, there is little information about MDRAB control. Therefore, this study evaluated infection control measures for A. baumannii infections, clusters and outbreaks in the literature.


METHODS
We performed a review of OVID Medline (from 1980 to 2015), and analyzed the literature.


RESULTS
We propose that both infection control programs and antibiotic control programs are essential for control of MDRAB. The first, effective control of MDRAB infections, requires compliance with a series of infection control methods including strict environmental cleaning, effective sterilization of reusable medical equipment, concentration on proper hand hygiene practices, and use of contact precautions, together with appropriate administrative guidance. The second strategy, effective antibiotic control programs to decrease A. baumannii, is also of paramount importance.


CONCLUSIONS
We believe that both infection control programs and antibiotics stewardship programs are essential for control of MDRAB infections.
The Infectious Disease Research Center, 135 Nan-Hsiao Street, Changhua 500, Taiwan. 76590@cch.org.tw.|Division of Infectious Disease, Department of Internal Medicine, 135 Nan-Hsiao Street, Changhua 500, Taiwan. 76590@cch.org.tw.
Chang-Hua
CH
Chen
The Infectious Disease Research Center, 135 Nan-Hsiao Street, Changhua 500, Taiwan. 3344@cch.org.tw.
Li-Chen
LC
Lin
Epidemiology and Biostatics Center, Changhua Christian Hospital, 135 Nan-Hsiao Street, Changhua 500, Taiwan. 83686@cch.org.tw.
Yu-Jun
YJ
Chang
Department of Pharmacy, Changhua Christian Hospital, 135 Nan-Hsiao Street, Changhua 500, Taiwan. 30855@cch.org.tw.
Yu-Min
YM
Chen
Division of Infectious Disease, Department of Internal Medicine, 135 Nan-Hsiao Street, Changhua 500, Taiwan. 106018@cch.org.tw.
Chin-Yen
CY
Chang
Department of Life Science, National Chung Hsing University, 250 Kuo-Kuang Road, Taichung 402, Taiwan. cchuang@dragon.nchu.edu.tw.
Chieh-Chen
CC
Huang
D000151:Acinetobacter Infections / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control* / Q000635:transmission; D040981:Acinetobacter baumannii / Q000187:drug effects*; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control* / Q000635:transmission; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects*; D006801:Humans; D017053:Infection Control / Q000379:methods*
D000900:Anti-Bacterial Agents
Acinetobacter baumannii complex; antibiotic control programs; infection control programs; multidrug-resistant