Testicular hypertrophy as a predictor for contralateral monorchism: Retrospective review of prospectively recorded data.
OBJECTIVE
Testicular hypertrophy has previously been evaluated as a predictor of monorchism. However, its implication in clinical practice is not well evaluated. The aim of the present study was to examine its value in planning the operative time.


METHODS
Medical charts of prospectively recorded data of 76 consecutive patients with unilateral impalpable testis from 2011 to 2014 were reviewed at the present institute. Inclusion criteria included prepubertal patients with non-palpable testes by examination under anesthesia. Contralateral testes were prospectively measured using a Takihara orchidometer. Orchiectomy or orchiopexy was performed according to the viability of the undescended testis (UDT). Collected data included age of surgery, contralateral testicular size, surgical time and laparoscopic findings. A ROC curve was used to define the best cut-off volume of the contralateral testis that can predict ipsilateral testicular viability. The Student's t-test was used to examine if this cut-off volume would be useful in allocating the operative time.


RESULTS
Of 76 patients, four palpable testes by examination under anesthesia were excluded. The remaining 72 patients were included in the study. Ipsilateral normal viable testes were found in 26 (36.1%) patients, while 46 (63.9%) had non-viable testes (testicular nubbins or vanishing testes) (Figure). A contralateral testicular volume > 2 ml was significantly predictive for monorchism with 71.7% sensitivity and 100% specificity (P < 0.001). The mean operative time for management of UDT with a contralateral size >2 ml was 50 min, which was significantly shorter than that for UDT with a contralateral size ≤ 2 ml, which was 88 min (P < 0.001).


CONCLUSIONS
In previously published reports, the cut-off value for testicular hypertrophy that predicts monorchism greatly varied. This is likely due to the different methods used for testicular measurements that make it impractical to make a direct comparison. The usefulness of predicting monorchism before surgery has not previously been used as a guide for allocating operative time in the management of a unilateral non-palpable testicle. This study had some limitations, including a relatively small sample size and involvement of different surgeons, which may have affected the operative time.


CONCLUSIONS
Using the cut-off volume of a contralateral testis >2 ml as a predictor for monorchism can reduce the allocated operative time by approximately one third.
Department of Pediatric Surgery, Urology, McGill University, 2300 Tupper, Montreal, QC, Canada. Electronic address: amr.hodhod@mail.mcgill.ca.
A
A
Hodhod
Department of Pediatric Surgery, Urology, McGill University, 2300 Tupper, Montreal, QC, Canada. Electronic address: jp.capolicchio@muhc.mcgill.ca.
J P
JP
Capolicchio
Department of Pediatric Surgery, Urology, McGill University, 2300 Tupper, Montreal, QC, Canada. Electronic address: roman.jednak@muhc.mcgill.ca.
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R
Jednak
Department of Pediatric Surgery, Urology, McGill University, 2300 Tupper, Montreal, QC, Canada. Electronic address: elsherbi@yahoo.com.
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M
El-Sherbiny
D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000175:diagnosis / Q000601:surgery*; D005500:Follow-Up Studies; D006061:Gonadal Dysgenesis, 46,XY / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D006984:Hypertrophy; D007223:Infant; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D056126:Orchiopexy / Q000379:methods*; D009929:Organ Size; D011237:Predictive Value of Tests; D011379:Prognosis; D012372:ROC Curve; D012189:Retrospective Studies; D013737:Testis / Q000002:abnormalities / Q000473:pathology* / Q000601:surgery
Cryptorchidism; Hypertrophy; Laparoscopy; Orchiopexy; Undescended testis