Copper-Catalyzed Dimerization/Cyclization of Itaconates.
A copper-catalyzed domino reaction between itaconate esters and diethyl zinc (or silane) is developed, affording itaconate dimerization products, multi-ester-substituted cyclopentanones, in moderate to high yields.
College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China. zqli501@163.com.
Zhiqiang
Z
Li
College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China. lrrnice@126.com.
Ruirui
R
Li
College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China. jianglan@dlu.edu.cn.
Lan
L
Jiang
College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China. znli@dl.cn.
Zhengning
Z
Li
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D019281:Dimerization; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry; D013386:Succinates / Q000138:chemical synthesis* / Q000737:chemistry; D015032:Zinc / Q000737:chemistry
D004952:Esters; D013386:Succinates; D003300:Copper; D015032:Zinc; C005229:itaconic acid
catalysis; copper; cyclopentanone; dimerization; domino reaction; itaconate