COMP: an endogenous thrombin inhibitor.
In this issue of Blood, Liang and colleagues demonstrate that cartilage oligomeric matrix protein (COMP) acts as a major endogenous plasma- and platelet-derived inhibitor of thrombin activity in vitro and in vivo.
CURTIN UNIVERSITY.
Pat
P
Metharom
CURTIN UNIVERSITY.
Michael C
MC
Berndt
D000818:Animals; D000991:Antithrombins / Q000097:blood*; D064236:Cartilage Oligomeric Matrix Protein / Q000097:blood*; D008297:Male; D013917:Thrombin / Q000037:antagonists & inhibitors* / Q000378:metabolism*
D000991:Antithrombins; D064236:Cartilage Oligomeric Matrix Protein; D013917:Thrombin