Genetics of Canine Primary Glaucomas.
Primary glaucomas are a leading cause of incurable vision loss in dogs. Based on their specific breed predilection, a genetic cause is suspected to be responsible, and affected dogs should be excluded from breeding. Despite the high prevalence of primary glaucomas in dogs, their genetics have been studied in only a small number of breeds. The identification of canine glaucoma disease genes, and the development of genetic tests, will help to avoid the breeding of affected dogs in the future and will allow for earlier diagnosis and potentially more effective therapy.
Department of Small Animal Clinical Sciences, Veterinary Medical Center, College of Veterinary Medicine, Michigan State University, 736 Wilson Road, Room D-208, East Lansing, MI 48824, USA. Electronic address: komaromy@cvm.msu.edu.
András M
AM
Komáromy
Department of Small Animal Clinical Sciences, Veterinary Medical Center, College of Veterinary Medicine, Michigan State University, 736 Wilson Road, Room D-208, East Lansing, MI 48824, USA.
Simon M
SM
Petersen-Jones
D000818:Animals; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D020022:Genetic Predisposition to Disease; D005901:Glaucoma / Q000235:genetics / Q000662:veterinary*
ADAMTS10; ADAMTS17; Canine; Closed-angle; Genetics; Glaucoma; Lens luxation; Open-angle