The Chemical Diversity of the Ascomycete Fungus Paecilomyces variotii.
Paecilomyces variotii isolated from a broad range of habitats drives the diversification of new high-value-added secondary metabolites that could potentially play an important role in human and animal health. These metabolites include the anhydride metabolite of the nonadride family, as well as the following compounds: naphthopyranone metabolites, sphingofungins, eicosenoic acids, new branched fatty acids, ascofuranone, polyketides, an anacardic acid analogue, straight-chain peptides, and volatile compounds. These natural products show that P. variotii can provide leading compounds for new drug discoveries, which may include herbicide agents, some of which are important in the agrochemical market. Finally, this review outlines recent developments, trends, and prospects for the chemistry of this ascomycete.
Department of Biochemistry, Federal University of Pernambuco - UFPE, Recife, Pernambuco, 50740-465, Brazil.
Roberto
R
Mioso
Department of Chemistry, University of Las Palmas de Gran Canaria - ULPGC, 35017, Las Palmas de Gran Canaria, Spain.
Francisco Javier
FJ
Toledo Marante
Department of Biology, University of Las Palmas de Gran Canaria - ULPGC, 35017, Las Palmas de Gran Canaria, Spain. ictiocentauros@hotmail.com.
Irma
I
Herrera Bravo de Laguna
D000818:Animals; D001688:Biological Products / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D009930:Organic Chemicals / Q000737:chemistry / Q000378:metabolism; D010143:Paecilomyces / Q000737:chemistry* / Q000378:metabolism
D001688:Biological Products; D009930:Organic Chemicals
Bioactive compounds; Byssochlamys spectabilis; Fungus; Paecilomyces variotii; Secondary metabolites