[Not Available].
Allergic contact eczema in children is frequent. If clinically suspected, a patch test should be performed. In the present study, data obtained from 116,742 patients who had undergone a patch test from 2005-2014 were analysed. The children group (range 0-12 years) included 925 patients. If at least 700 tested individuals were considered, the most frequent sensitizations in this group were nickel sulfate (8.5 %), fragrance mix I (5.5 %), and colophony (3.4 %), whereby sensitisation in adults was higher for nickel sulfate (15.5 %) and fragrance mix 1 (8.4 %), while being similar for colophony (3.7 %). In adolescents with and without a profession, nickel sulfate (11.1 and 13.6 %, respectively) and cobalt (II) chloride (3.9 and 3.4 %, respectively) were the most frequent positively tested contact allergens. Sensitisations toward fragrance mix I was low (3.9 and 3.4 %, respectively) in comparison to the adult group (8.4 %). In both children and adolescents, toluene diamine and paraphenylenediamine sensitizations were not infrequent, but it must be considered that these allergens were only tested if suspected. The data show that the sensitisation profile among children and adolescents display patterns similar to those in adults. Sensitisations in childhood and adolescence towards dyes like paraphenylendiamine may be associated with increased use of tattooing in these groups.
Klinik für Dermatologie, Venerologie und Allergologie, Allergie-Centrum-Charité, Charité-Universitätsmedizin, Campus Charité Mitte, Charitéplatz 1, 10117, Berlin, Deutschland. margitta.worm@charite.de.
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M
Worm
Klinik für Dermatologie, Venerologie und Allergologie, Universitätsmedizin Göttingen, Georg-August-Universität, Göttingen, Deutschland.
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U
Lippert
Informationsverbund Dermatologischer Kliniken (IVDK), Universität Göttingen, Georg-August-Universität, Göttingen, Deutschland.
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J
Geier
Informationsverbund Dermatologischer Kliniken (IVDK), Universität Göttingen, Georg-August-Universität, Göttingen, Deutschland.
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Schnuch
D000293:Adolescent; D000067697:Adolescent Health / Q000706:statistics & numerical data; D017677:Age Distribution; D002648:Child; D000067576:Child Health / Q000706:statistics & numerical data; D002675:Child, Preschool; D004396:Coloring Agents; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology; D009783:Dermatitis, Occupational / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010328:Patch Tests / Q000706:statistics & numerical data*; D012307:Risk Factors; D017678:Sex Distribution; D013653:Tattooing / Q000706:statistics & numerical data*
D004396:Coloring Agents
Adolescents; Allergens; Children; Patch tests; Sensitization