New Polyprenylated Phloroglucinol and Other Compounds Isolated from the Fruits of Clusia nemorosa (Clusiaceae).
Clusia nemorosa has been widely used in folk medicine to treat various ailments, including headaches and inflammation. Investigation of the fruits of Clusia nemorosa (Clusiaceae) led to the isolation and characterization of a new phloroglucinol derivative, named 6S,8S,28S-nemorosic acid (1), together with seven known compounds: friedelin (2), β-sitosterol (3), stigmasterol (4), β-sitosterol glycoside (5), kaempferol (6), quercetin (7) and dimethyl citrate (8). The structures were determined by extensive 1D- and 2D-NMR, CD and MS spectroscopic analyses.
Departamento de Química, Universidade Federal Rural do Rio de Janeiro, 23890-000 Seropédica, Brazil. rafaellaoliveira@ufrrj.br.
Rafaela Oliveira
RO
Ferreira
Departamento de Ciências Moleculares, Universidade Federal Rural de Pernambuco, 52171-900 Recife, Brazil. sarmentosilva@gmail.com.
Tania Maria Sarmento
TM
da Silva
Departamento de Química, Universidade Federal Rural do Rio de Janeiro, 23890-000 Seropédica, Brazil. mgeraldo@ufrrj.br.
Mário Geraldo
MG
de Carvalho
D028084:Clusiaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification; D005638:Fruit / Q000737:chemistry; D008279:Magnetic Resonance Imaging; D008519:Medicine, Traditional; D019906:Nuclear Magnetic Resonance, Biomolecular; D010696:Phloroglucinol / Q000737:chemistry* / Q000302:isolation & purification
D005419:Flavonoids; D010696:Phloroglucinol
Clusia nemorosa; Clusiaceae; flavonoid; nemorosic acid; phloroglucinol; triterpenoid