Economic resources consumption structure in severe hypoglycemia episodes: a systematic review and meta-analysis.
Diabetes mellitus (DM) is associated with severe hypoglycemia events (SHEs) that vary in severity and resource consumption. Here we perform a systematic review in Medline of studies evaluating SHE-related health resource use. Eligible studies investigated patients with DM and included ≥10 SHEs. We also assessed studies identified in another systematic review, and through references from the included studies. We identified 14 relevant studies and used data from 11 (encompassing 6075 patients). Study results were interpreted to fit our definitions, which sometimes required assumptions. SHE type structure was synthesized using Bayesian modeling. Estimating Type 1 & 2 DM separately revealed only small differences; therefore, we used joint results. Of the analyzed SHEs, 9.97% were hospital-treated, 22.3% medical professional-treated, and 67.73% family-treated. These meta-analysis results help in understanding the structure of resource consumption following SHE and can be used in economic studies.
a 1 Decision Analysis and Support Unit, Warsaw School of Economics, Al. Niepodległości 162, Warsaw, Poland.
Michał
M
Jakubczyk
b 2 HealthQuest spółka z ograniczoną odpowiedzialnością Sp. K, 02-554 Warsaw, Poland.
Elżbieta
E
Rdzanek
c 3 Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Warsaw, Poland.
Maciej
M
Niewada
d 4 Novo Nordisk Pharma sp. z o.o., Warsaw, Poland.|e 5 Department of Pharmacoeconomics, Medical University of Warsaw, Warsaw, Poland.
Marcin
M
Czech
D001499:Bayes Theorem; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000191:economics*; D017048:Health Care Costs; D006295:Health Resources / Q000706:statistics & numerical data; D006760:Hospitalization / Q000191:economics / Q000706:statistics & numerical data; D006801:Humans; D007003:Hypoglycemia / Q000191:economics* / Q000209:etiology / Q000628:therapy; D012720:Severity of Illness Index
cost analysis; diabetes mellitus; hospitalization; resource usage; severe hypoglycemia