Diffuse Ganglioneuromatosis of the Colon Presenting as a Large Subepithelial Tumor in Adults: Report of Two Cases.
Colonic diffuse ganglioneuromatosis is a benign neoplastic condition characterized by disseminated, intramural, or transmural proliferation of neural elements involving the enteric plexuses, sometimes associated with von Recklinghausen's disease and other multiple tumor syndromes. Colonic diffuse ganglioneuromatosis is usually large, ranging from 1 to 17 cm, and thus can distort the surrounding tissue architecture as well as infiltrate the adjacent bowel wall. However, colonic diffuse ganglioneuromatosis is an exceptional finding in adults and only individual cases are reported in the literature. Herein, we report two unusual cases of adult patients with colonic diffuse transmural ganglioneuromatosis presenting as a large subepithelial tumor.
Departments of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Tae-Jun
TJ
Kim
Departments of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Hyun
H
Lim
Departments of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Ho Suk
HS
Kang
Departments of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Sung Hoon
SH
Moon
Departments of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Jong Hyeok
JH
Kim
Departments of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Choong Kee
CK
Park
Departments of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Mi Jung
MJ
Kwon
Departments of Surgery , Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Bong Hwa
BH
Lee
D000328:Adult; D000368:Aged; D003106:Colon / Q000378:metabolism / Q000473:pathology*; D003113:Colonoscopy; D005729:Ganglioneuroma / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009418:S100 Proteins / Q000378:metabolism; D014057:Tomography, X-Ray Computed
D009418:S100 Proteins
Colon; Endoscopy; Ganglioneuroma; Subepithelial tumor