[METHOD FOR DETERMINING EROSIVE LESIONS OF THE GASTRIC MUCOUSA IN CHILDREN WITH JUVENILE ARTHRITIS].
To detect the clinical diagnostic criteria for non-invasive diagnosis of erosive gastritis in children with juvenile arthritis have been studied the 92 children aged 9 to 16 years (mean age-13,9 ± 2,3 years) with verified diagnosis of juvenile arthritis, of whom 10 had erosive gastritis (group 1) and 82 without erosions (group 2). A comparison of the groups on 23 grounds by analysis of contingency tables and the subsequent discriminant analysis, has developed a new non-invasive method for determining the erosive lesions of the mucous membrane of the stomach in children with juvenile arthritis, including a score of history, complaints and the results of laboratory studies the level of the G-17, pepsinogen I, pepsinogen II, and the ratio of pepsinogen I to pepsinogen II, the presence of autoantibodies to the H+, K+/ATPase of the parietal cells of the stomach, the test for occult blood "Colon View Hb and Hb/Hp". Developed a diagnostic table, including 11 features with scores each. The total score 27 or higher allows a high degree of probability to determine the erosive lesions of the gastric mucosa in children with juvenile arthritis.
A P
AP
Listopadova
V P
VP
Novikova
I U
IU
Melnikova
A N
AN
Petrovskiy
N V
NV
Slizovskiy
D000293:Adolescent; D001171:Arthritis, Juvenile / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D001323:Autoantibodies / Q000097:blood*; D002648:Child; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism / Q000473:pathology; D005755:Gastrins / Q000097:blood*; D005756:Gastritis / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D020116:Pepsinogen A / Q000097:blood*; D020115:Pepsinogen C / Q000097:blood*
D001323:Autoantibodies; D005755:Gastrins; C013550:gastrin 17; D020115:Pepsinogen C; D020116:Pepsinogen A