Assessment of hematologic parameters before and after bimaxillary orthognathic surgery.
OBJECTIVE
The purpose of the study was to evaluate changes of hematologic parameters in bimaxillary surgery.


METHODS
Fifty-three patients were prospectively evaluated and divided into groups based on the surgical procedure and sex (predictor variables). Hemoglobin, red blood cells, hematocrit, and platelet were the primary outcome variables, operation time the secondary outcome, and the patients' age and weight the other variables.


BACKGROUND
NCT02364765 (U.S. National Institutes of Health, clinicaltrials.gov).


RESULTS
There was statistically significant difference between all hematologic parameters before and after surgery, for both men and women, and for all surgical groups. There was a positive correlation between operative time and the decrease (in %) of the hematologic parameters. Linear regression analysis suggested that the Hb values decrease 0.083 % for every minute increase in the operation time, and 0.066, 0.066, and 0.010 % for RBC, Hct, and platelet count, respectively. There was a negative correlation between weight and all hematologic parameters. Correlations between age and hematologic parameters were not statistically significant. Almost all correlations between age, weight, sex, and the surgery group and the hematologic parameters were considered as very weak. Only one patient was transfused.


CONCLUSIONS
It is suggested that operation time and patient's weight play a bigger role than patient's age and sex in the decrease of hematologic parameters after bimaxillary surgery.
Department of Prosthodontics, Faculty of Odontology, Malmö University, Carl Gustafs väg 34, SE-205 06, Malmö, Sweden. bruno.chrcanovic@mah.se.
Bruno Ramos
BR
Chrcanovic
Oral and Maxillofacial Surgery Service, Baleia Hospital, Belo Horizonte, Brazil.
Guilherme Lacerda de
GL
Toledo
Oral and Maxillofacial Surgery Service, Baleia Hospital, Belo Horizonte, Brazil.
Márcio Bruno Figueiredo
MB
Amaral
Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Brazil.|Department of Oral and Maxillofacial Surgery, School of Dentistry, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte, Brazil.
Antônio Luís Neto
AL
Custódio
D000293:Adolescent; D000328:Adult; D016063:Blood Loss, Surgical; D004906:Erythrocyte Count; D005260:Female; D006400:Hematocrit; D006452:Hemoglobinometry; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery*; D008875:Middle Aged; D061646:Operative Time; D056948:Orthognathic Surgical Procedures; D010976:Platelet Count; D011183:Postoperative Complications / Q000097:blood*; D011446:Prospective Studies; D013223:Statistics as Topic; D055815:Young Adult
Bimaxillary osteotomies; Blood parameters; Hematocrit; Hemoglobin; Orthognathic surgery; Platelets; Red blood cells