Scedosporium apiosermum infection of the "Native" valve: Fungal endocarditis in an orthotopic heart transplant recipient.
Scedosporium apiospermum is an increasingly appreciated pathogen in immunosuppressed patients. We present a case of S. apiospermum endocarditis in a 70-year-old male who had undergone orthotopic heart transplant. Echocardiogram demonstrated a 1.4 cm tricuspid valve vegetation. He underwent valve replacement, complicated by fatal massive post-operative haemorrhage. Valve cultures grew S. apiospermum. To our knowledge, our case is the first reported instance of endocarditis caused by S. apiospermum in a recipient of a cardiac transplant.
Division of Infectious Diseases, Duke University Medical Center, Durham, NC USA.
Meredith E
ME
Clement
Division of Infectious Diseases, Duke University Medical Center, Durham, NC USA.
Eileen K
EK
Maziarz
Division of Cardiovascular and Thoracic Surgery, Duke University Medical Center, Durham, NC, USA.
Jacob N
JN
Schroder
Division of Cardiology, Duke University Medical Center, Durham, NC, USA.
Chetan B
CB
Patel
Division of Infectious Diseases, Duke University Medical Center, Durham, NC USA.
John R
JR
Perfect
Fungal endocarditis; Orthotopic heart transplant; Pseudallescheria boydii; Scedosporiosis; Scedosporium apiospermum