Pathogenesis and Management of Buerger's Disease.
Buerger's disease or thromboangiitis obliterans causes pain, ulceration, or gangrene in the lower or upper extremity. It is associated with chronic cigarette smoking and is believed to be an immune mediated vasculitis. The pathogenesis is still unknown but recent postulate of its association with odontal bacteria has generated much renewed interest. Despite its recognition more than a century ago, little progress has been made in its treatment. Until the pathogenesis is elucidated, abstinence from cigarette is the only effective therapy.
Universiti Putra Malaysia, Serdang, Selangor, Malaysia liewnc@yahoo.com.
Ngoh Chin
NC
Liew
Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Limi
L
Lee
Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Zubaidah
Z
Nor Hanipah
Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Tikfu
T
Gee
Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Mohd Faisal
MF
Jabar
D000367:Age Factors; D019468:Disease Management; D006801:Humans; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D013919:Thromboangiitis Obliterans / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
Buerger’s disease; arteritis; vasculitis