Emergence of extensive drug-resistant (XDR) Acinetobacter baumanniiin the Clinical Center University of Sarajevo, Bosnia and Herzegovina.
OBJECTIVE
Recently increased attention and interest for Acinetobacterbaumannii are the result of the occurrence of multidrug resistant (MDR), extensive drug resistant (XDR) and pandrug resistant (PDR) isolates around the world. The aim of this study was to examine the resistance of A. baumannii isolates to antimicrobials in Clinical Centre University of Sarajevo, Bosnia and Herzegovina.


METHODS
Two hundred and fifty-seven A.baumannii isolates were collected between July 2011 and June 2012 in different wards and from different clinical samples. Multidrug resistant, XDR and PDR were defined according to international expert proposal for interim standard definitions for acquired resistance.


RESULTS
A total of 257 A. baumannii isolates showed eleven different patterns of resistance, of which ten patterns corresponded to MDR and one corresponded to XDR (sensitive only to colistin). Multidrug resistant and XDR strains were the most common at Intensive Care Units and surgical departments. The largest numbers of isolates were found in wound swabs, blood and bronchial aspirate.


CONCLUSIONS
This is the first report of XDR A. baumannii in the 2000-bed Clinical Centre University of Sarajevo, Bosnia-Herzegovina. Although XDR strains have been detected, the resistance to colistin has not. The elevated prevalence of these strains indicates that local antibiotic prescription policies should be revised and infection prevention and control should be improved.
Department of Clinical microbiology, Clinical Centre University of Sarajevo; Bosnia and Herzegovina.
Amela
A
Dedeić-Ljubović
Department of Clinical microbiology, Clinical Centre University of Sarajevo; Bosnia and Herzegovina.
Đana
Đ
Granov
Department of Medical Science, Academy of Sciences and Arts of Bosnia and Herzegovina, 3International Burch University; Sarajevo; Bosnia and Herzegovina.
Mirsada
M
Hukić
D040981:Acinetobacter baumannii / Q000187:drug effects / Q000302:isolation & purification*; D017522:Bosnia and Herzegovina; D024901:Drug Resistance, Multiple, Bacterial; D006785:Hospitals, University; D006801:Humans
antimicrobials; intensive care unit; nosocomial infections