E. coli MG1655 modulates its phospholipid composition through the cell cycle.
This paper describes a study of the phospholipid profile of Escherichia coli MG1655 cultures at the B and D periods of the cell cycle. The results indicate that the phosphatidyl glycerol fraction grows relatively rapidly and that the size of the cardiolipin (CL) fraction does not grow at all during cell elongation. This is consistent with observations that CL is located preferentially at the poles of E. coli. It also suggests that lipid production is controlled as a function of the cell cycle.
Membrane Biochemistry and Biophysics, Department of Chemistry, Universiteit Utrecht, Kruytgebouw, Padualaan 8, 3584 CH Utrecht, The Netherlands. Electronic address: s.r.furse@uu.nl.
Samuel
S
Furse
NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Department of Chemistry, Universiteit Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Hans
H
Wienk
NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Department of Chemistry, Universiteit Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Rolf
R
Boelens
Membrane Biochemistry and Biophysics, Department of Chemistry, Universiteit Utrecht, Kruytgebouw, Padualaan 8, 3584 CH Utrecht, The Netherlands.
Anton I P M
AI
de Kroon
Membrane Biochemistry and Biophysics, Department of Chemistry, Universiteit Utrecht, Kruytgebouw, Padualaan 8, 3584 CH Utrecht, The Netherlands.
J Antoinette
JA
Killian
D002453:Cell Cycle; D004926:Escherichia coli / Q000737:chemistry* / Q000166:cytology* / Q000254:growth & development / Q000378:metabolism; D010743:Phospholipids / Q000096:biosynthesis / Q000737:chemistry*
D010743:Phospholipids
Cell cycle; Cell cycle control; Lipid; Lipid metabolism; Lipidomic