Fistulizing Epstein-Barr virus-positive plasmablastic lymphoma in an HIV-positive man.
Plasmablastic lymphoma (PBL) is an unusual subtype of non-Hodgkin lymphoma recently classified as a diffuse immunoblastic lymphoma with a plasma-cell immunophenotype. Originally described in the oral cavity of HIV-positive patients, it has also been recognized to occur rarely at other sites. We describe a previously unreported fistulizing presentation of Epstein-Barr virus (EBV)-positive PBL, reviewing its association with HIV-1 infection and its importance as an AIDS-defining malignancy.
Kaiser Permanente, Department of Dermatology, Sacramento, CA, U.S.A.
J
J
Rangel
Stanford University, Department of Pathology, Department of Dermatology, Stanford, CA, U.S.A.
R
R
Novoa
Baylor College of Medicine, Department of Surgery, Houston, TX, U.S.A.
C
C
Morrison
Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, U.S.A.
D
D
Frank
Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, U.S.A.|Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, PA, U.S.A.
C
C
Kovarik
D017088:AIDS-Related Opportunistic Infections / Q000473:pathology; D001005:Anus Neoplasms / Q000473:pathology* / Q000821:virology; D001706:Biopsy; D020031:Epstein-Barr Virus Infections / Q000473:pathology*; D006679:HIV Seropositivity; D004854:Herpesvirus 4, Human; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069293:Plasmablastic Lymphoma / Q000473:pathology* / Q000821:virology; D012003:Rectal Fistula / Q000473:pathology* / Q000821:virology