Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy.
Skin lesions are commonly treated using laser heating. However, the introduction of new devices into clinical practice requires evaluation of their performance. This study presents the application of optical phantoms for assessment of a newly developed 975-nm pulsed diode laser system for dermatological purposes. Such phantoms closely mimic the absorption and scattering of real human skin (although not precisely in relation to thermal conductivity and capacitance); thus, they can be used as substitutes for human skin for approximate evaluation of laser heating efficiency in an almost real environment. Thermographic imaging was applied to measure the spatial and temporal temperature distributions on the surface of laser-irradiated phantoms. The study yielded results of heating with regard to phantom thickness and absorption, as well as laser settings. The methodology developed can be used in practice for preclinical evaluations of laser treatment for dermatology.
Gdansk University of Technology, Faculty of Electronics, Telecommunications and Informatics, Department of Metrology and Optoelectronics, Narutowicza 11/12, Gdansk 80-233, Poland.
Maciej S
MS
Wróbel
Gdansk University of Technology, Faculty of Electronics, Telecommunications and Informatics, Department of Metrology and Optoelectronics, Narutowicza 11/12, Gdansk 80-233, Poland.
Malgorzata
M
Jedrzejewska-Szczerska
Gdansk University of Technology, Faculty of Electronics, Telecommunications and Informatics, Department of Metrology and Optoelectronics, Narutowicza 11/12, Gdansk 80-233, Poland.
Stanislaw
S
Galla
Polish Academy of Sciences, The Szewalski Institute of Fluid-flow Machinery, Physical Aspects of Ecoenergy Department, Fiszera 14, Gdansk 80-952, Poland.
Leszek
L
Piechowski
Polish Academy of Sciences, The Szewalski Institute of Fluid-flow Machinery, Physical Aspects of Ecoenergy Department, Fiszera 14, Gdansk 80-952, Poland.
Miroslaw
M
Sawczak
University of Oulu, Faculty of Information Technology and Electrical Engineering, Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, FI-90014 Oulu, FinlanddTomsk State University, 36 Lenina Avenue, Tomsk 634050, Russia.
Alexey P
AP
Popov
University of Oulu, Faculty of Information Technology and Electrical Engineering, Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, FI-90014 Oulu, FinlanddTomsk State University, 36 Lenina Avenue, Tomsk 634050, Russia.
Alexander V
AV
Bykov
University of Oulu, Faculty of Information Technology and Electrical Engineering, Optoelectronics and Measurement Techniques Laboratory, P.O. Box 4500, FI-90014 Oulu, FinlanddTomsk State University, 36 Lenina Avenue, Tomsk 634050, RussiaeSaratov State Uni.
Valery V
VV
Tuchin
Polish Academy of Sciences, The Szewalski Institute of Fluid-flow Machinery, Physical Aspects of Ecoenergy Department, Fiszera 14, Gdansk 80-952, Poland.
Adam
A
Cenian
D040761:Biomimetic Materials / Q000138:chemical synthesis* / Q000528:radiation effects*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation* / Q000379:methods; D008027:Light; D055096:Optical Devices; D019047:Phantoms, Imaging; D012871:Skin Diseases / Q000503:physiopathology / Q000628:therapy*; D012881:Skin Temperature / Q000528:radiation effects*