Intestinal Transplantation: International Outcomes.
Intestinal transplantation has continued to evolve over the past decade. Fewer patients have received intestine transplants in the past 5 years, perhaps due to efforts in intestine rehabilitation. Despite improvement in earlier outcomes, long-term survival has remained steady over the past decade. This is potentially due to the complications of immunosuppression, as well as inherent poor graft half-life due to chronic rejection. Improvements in outcome will require multidisciplinary efforts to understand the long-term mechanisms of intestine graft acceptance and to properly optimize and individualize immunosuppression for the transplant recipient.
Armando J
AJ
Ganoza
Doug G
DG
Farmer
Max A
MA
Marquez
George V
GV
Mazariegos
D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control; D006085:Graft Survival / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007422:Intestines / Q000276:immunology / Q000637:transplantation*; D016377:Organ Transplantation / Q000009:adverse effects / Q000401:mortality / Q000639:trends; D012042:Registries; D012307:Risk Factors; D012778:Short Bowel Syndrome / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D013997:Time Factors; D009927:Tissue and Organ Procurement / Q000458:organization & administration / Q000639:trends; D016896:Treatment Outcome
D007166:Immunosuppressive Agents