Ion manipulations in structures for lossless ion manipulations (SLIM): computational evaluation of a 90° turn and a switch.
The process of redirecting ions through 90° turns and 'tee' switches utilizing Structures for Lossless Ion Manipulations (SLIM) was evaluated at 4 Torr pressure using SIMION simulations and theoretical methods. The nature of pseudo-potential in SLIM-tee structures has also been explored. Simulations show that 100% transmission efficiency in SLIM devices can be achieved with guard electrode voltages lower than ∼10 V. The ion plume width in these conditions is ∼1.6 mm while at lower guard voltages lead to greater plume widths. Theoretical calculations show marginal loss of ion mobility resolving power (<5%) during ion turn due to the finite plume widths (i.e. race track effect). More robust SLIM designs that reduce the race track effect while maximizing ion transmission are also reported. In addition to static turns, the dynamic switching of ions into orthogonal channels was also evaluated both using SIMION ion trajectory simulations and experimentally. Simulations and theoretical calculations were in close agreement with experimental results and were used to develop more refined SLIM designs.
Biological Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, WA 99352, USA. rds@pnnl.gov.
Sandilya V B
SV
Garimella
Yehia M
YM
Ibrahim
Ian K
IK
Webb
Andreas B
AB
Ipsen
Tsung-Chi
TC
Chen
Aleksey V
AV
Tolmachev
Erin S
ES
Baker
Gordon A
GA
Anderson
Richard D
RD
Smith
D013058:Mass Spectrometry / Q000379:methods*; D008962:Models, Theoretical; D009038:Motion; D011312:Pressure