Sclerosing angiomatoid nodular transformation of spleen masquerading as a splenic abscess.
Here we report an incidental case of sclerosing angiomatoid nodular transformation (SANT) in an open splenectomy specimen from a young man who presented with insidious abdominal pain. The condition was mimicking as a splenic abscess. Histopathological and immunohistochemical analysis confirmed this to be SANT. SANT presents a diagnostic challenge to clinicians, radiologists, as well as pathologists because of its extreme rarity. Therefore, it must be included as a differential diagnosis in cases with nonspecific pain or radiological splenic mass. This case highlights that SANT can present with varied clinical features and at a wide range of ages. A high index of suspicion is required for its diagnosis.
Department of Pathology, Armed Forces Medical College, Pune, Maharashtra, India.
Kunal Ashok
KA
Bagul
Arijit
A
Sen
D015746:Abdominal Pain / Q000175:diagnosis / Q000209:etiology; D000038:Abscess / Q000175:diagnosis* / Q000473:pathology*; D000798:Angiomatosis / Q000175:diagnosis* / Q000473:pathology*; D015703:Antigens, CD / Q000032:analysis; D018952:Antigens, CD34 / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D003937:Diagnosis, Differential; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008853:Microscopy; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D011860:Radiography, Abdominal; D013154:Spleen / Q000473:pathology*; D013158:Splenic Diseases / Q000175:diagnosis* / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D055815:Young Adult; D000097382:CD68 Molecule
D015703:Antigens, CD; D018952:Antigens, CD34; D015214:Antigens, Differentiation, Myelomonocytic; D019408:Platelet Endothelial Cell Adhesion Molecule-1; C067980:CD68 antigen, human; D000097382:CD68 Molecule