A rare case of extra nodal Rosai-Dorfman disease with isolated multifocal osseous manifestation.
Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai-Dorfman disease is a non-neoplastic condition which typically presents as massive, bilateral cervical lymphadenopathy and can involve multiple extranodal organ systems such as skin, eyes, and upper respiratory tract in about 28% cases. Bone lesions in association with nodal disease are seen in less than 10% cases. Isolated bone involvement as the only manifestation of SHML is extremely rare, with less than 50 cases reported in the literature. We report a very uncommon case of Rosai-Dorfman disease with isolated multifocal osseous involvement as the only presenting feature, involving about 10 different sites with no lymphadenopathy or other organ system involvement.
Department of Radiology, Musculoskeletal and Body MRI Division, University of Arkansas for Medical Sciences, Arkansas, USA.
Maharshi H
MH
Patel
Department of Radiology, Musculoskeletal and Body MRI Division, University of Arkansas for Medical Sciences, Arkansas, USA.
Kedar R
KR
Jambhekar
Department of Radiology, Musculoskeletal and Body MRI Division, University of Arkansas for Medical Sciences, Arkansas, USA.
Tarun
T
Pandey
Department of Radiology, Musculoskeletal and Body MRI Division, University of Arkansas for Medical Sciences, Arkansas, USA.
Roopa
R
Ram
Extra nodal; Rosai-Dorfman; histiocytes