Well-differentiated mucinous uterine adenocarcinoma predominantly diagnosed as adenoma malignum: a case report with an immunohistochemical analysis.
Adenoma malignum (AM), also referred to as "minimal deviation adenocarcinoma", is an extremely uncommon variant of highly-differentiated adenocarcinoma of the uterine cervix. The study presented herein describes a case of uterine AM found out after hysteroscopy. An early-stage, well-differentiated mucinous uterine adenocarcinoma was diagnosed post-operatively. A subsequent immunohistochemical assessment of a panel of antibodies was applied, in order to distinguish between female genital tract malignancies.
IIND Department of Gynecology, Lublin Medical University Lublin, Poland.
Andrzej
A
Semczuk
IIND Department of Gynecology, Lublin Medical University Lublin, Poland.
Jacek
J
Tomaszewski
IIND Department of Gynecology, Lublin Medical University Lublin, Poland.
Marek
M
Gogacz
Medical Department Rzeszów, Poland.
Bogdan
B
Obrzut
Reseach Unit in Medicine and Translational Oncology, Vall d'Hebron Research Institute and Autonomous University of Barcelona Barcelona, Spain.
Marina
M
Rigau
Department of Clinical Pathology, Lublin Medical University Lublin, Poland.
Dorota
D
Lewkowicz
Department of Obstetrics and Pathology of Pregnancy, Lublin Medical University Lublin, Poland.
Anna
A
Semczuk-Sikora
D002288:Adenocarcinoma, Mucinous / Q000737:chemistry* / Q000473:pathology / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis*; D002454:Cell Differentiation; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000737:chemistry* / Q000473:pathology / Q000601:surgery
D014408:Biomarkers, Tumor
Adenoma malignum; immunohistochemistry; uterine cancer