A remarkable enhancement of selectivity towards versatile analytes by a strategically integrated H-bonding site containing phase.
A double β-alanylated L-glutamide-derived organic phase has been newly designed and synthesized in such a way that integrated H-bonding (interaction) sites make it very suitable for the separation of versatile analytes, including shape-constrained isomers, and nonpolar, polar and basic compounds. The β-alanine residues introduced into two long-chain alkyl group moieties provide ordered polar groups through H-bonding among the amide groups.
Department of Applied Chemistry and Biochemistry, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan. ihara@kumamot-u.ac.jp abulkmallik@yahoo.com.
Abul K
AK
Mallik
Hongdeng
H
Qiu
Yutaka
Y
Kuwahara
Makoto
M
Takafuji
Hirotaka
H
Ihara
D018698:Glutamic Acid / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry*; D006860:Hydrogen Bonding; D015394:Molecular Structure; D013696:Temperature
D018698:Glutamic Acid