The New Director of "the Spermatogonial Niche": Introducing the Peritubular Macrophage.
In this issue of Cell Reports, DeFalco et al. (2015) characterize a novel macrophage population associated with the peritubular lamina of mouse testes. These macrophages may create a niche not for the self-renewal of stem cells but rather the induction of their differentiation.
Department of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, TX 77030, USA. Electronic address: meistrich@mdanderson.org.
Marvin L
ML
Meistrich
Department of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, TX 77030, USA.
Gunapala
G
Shetty
D000818:Animals; D008264:Macrophages / Q000378:metabolism*; D008297:Male; D013091:Spermatogenesis; D013093:Spermatogonia / Q000166:cytology*; D055153:Stem Cell Niche; D013737:Testis / Q000166:cytology*