The ultrasonographic detection of follicular rupture at the time of intrauterine insemination: is it really decisive?
Our aim is to assess the impact of the ultrasonographic detection of follicular rupture on the intrauterine insemination success. A total of 313 women undergoing ovarian stimulation for intrauterine insemination were enrolled. Transvaginal ultrasonography was performed to check whether the dominant follicle had ruptured and according to that the patients were divided into two groups. The ultrasound detection of follicular rupture was observed in 156 patients (54%). The independent variables favoring follicular rupture were: Age (t: 7.646, p < 0.0005), FSH value (t: -5.637, p < 0.0005), duration of infertility (t: -4.265, p < 0.0005), menstrual cycle length (t: -4.927, p < 0.0005). Moreover, the logistic regression analysis demonstrated that the predictive variables for follicular rupture were: FSH value (OR 1.7, CI 95% 1.3-2.3, p < 0.0005), duration of infertility (OR 2.6, CI 95% 1.6-4.2, p < 0.0005) and menstrual cycle length (OR 2.4, CI 95% 1.7-3.4, p < 0.0005). Pregnancy occurred in 23 patients of the group A (14.7%) and in 22 patients of the group B (16.5%) without a significant difference (p = 0.6). The logistic regression analysis confirmed that neither the evidence of follicular rupture nor any other variables influenced the pregnancy rate.
a Department of Morphology , Surgery and Experimental Medicine, Section of Obstetrics and Gynecology, University of Ferrara , Ferrara , Italy .
Emilio
E
Giugliano
b Faculty of Medicine , Second University of Naples , Naples , Italy .
Carola
C
Caldarelli
a Department of Morphology , Surgery and Experimental Medicine, Section of Obstetrics and Gynecology, University of Ferrara , Ferrara , Italy .
Brunella
B
Giugliano
c Santa Maria della Misericordia Hospital, Section of Obstetrics and Gynecology , Rovigo , Italy , and.
GianCarlo
G
Stellin
d Department of Woman's Health and Territorial Medicine, Faculty of Medicine and Psychology , University of Rome La Sapienza , Rome , Italy.
Donatella
D
Caserta
d Department of Woman's Health and Territorial Medicine, Faculty of Medicine and Psychology , University of Rome La Sapienza , Rome , Italy.
Massimo
M
Moscarini
a Department of Morphology , Surgery and Experimental Medicine, Section of Obstetrics and Gynecology, University of Ferrara , Ferrara , Italy .
Roberto
R
Marci
D000328:Adult; D005260:Female; D006801:Humans; D007315:Insemination, Artificial; D006080:Ovarian Follicle / Q000000981:diagnostic imaging*; D010062:Ovulation Induction; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D016896:Treatment Outcome; D014463:Ultrasonography
Female infertility; insemination; ovarian follicle; ovulation detection