Differentially functionalized acyclic cucurbiturils: synthesis, self-assembly and CB[6]-induced allosteric guest binding.
We report the synthesis of mono- and difunctionalized acyclic cucurbit[n]uril-type containers (1HA, 1HDA, 2HDA) which bear hexylammonium and hexanediammonium arms. The intra- and intermolecular assembly processes of 1HA, 1HDA, 2HDA as well as the ability of CB[n] to trigger allosteric host–guest binding toward guests 9–11 are presented.
Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA. LIsaacs@umd.edu.
Mingming
M
Zhang
David
D
Sigwalt
Lyle
L
Isaacs
D000494:Allosteric Regulation; D047028:Macrocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D066244:Proton Magnetic Resonance Spectroscopy; D000099246:Cucurbit(n)urils
D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils