Ammonium Iodide Induced Nonradical Regioselective Sulfenylation of Flavones via a C-H Functionalization Process.
A novel and highly regioselective ammonium iodide-induced nonradical sulfenylation method for the construction of a C-S bond was developed via C-H functionalization. With DMSO or R(1)SO2NHNH2 as a sulfenylating agent, MeS- and R(1)S-substituted flavone derivatives were obtained in good yields. This method enriches current C-S bond formation chemistry, making it a highly valuable and practical method in pharmaceutical industry.
Pharmacy School, Jiangsu University , Xuefu Road 301, Zhenjiang City, Jiangsu 212013, China.
Wannian
W
Zhao
Scientific Information Research Institute, Jiangsu University (Library) , Xuefu Road 301, Zhenjiang City, Jiangsu 212013, China.
Ping
P
Xie
Pharmacy School, Jiangsu University , Xuefu Road 301, Zhenjiang City, Jiangsu 212013, China.
Zhaogang
Z
Bian
Pharmacy School, Jiangsu University , Xuefu Road 301, Zhenjiang City, Jiangsu 212013, China.
Aihua
A
Zhou
Department of Chemistry and Chemical Biology, Indiana University Purdue University Indianapolis , Indianapolis, Indiana 46202, United States.
Haibo
H
Ge
Pharmacy School, Jiangsu University , Xuefu Road 301, Zhenjiang City, Jiangsu 212013, China.
Min
M
Zhang
Pharmacy School, Jiangsu University , Xuefu Road 301, Zhenjiang City, Jiangsu 212013, China.
Yingcai
Y
Ding
Pharmacy School, Jiangsu University , Xuefu Road 301, Zhenjiang City, Jiangsu 212013, China.
Lian
L
Zheng
D064751:Ammonium Compounds; D002384:Catalysis; D047309:Flavones / Q000737:chemistry*; D006860:Hydrogen Bonding; D015394:Molecular Structure; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*
D064751:Ammonium Compounds; D047309:Flavones; D000644:Quaternary Ammonium Compounds; D013438:Sulfhydryl Compounds; C582942:ammonium iodide; C043562:flavone