Synthesis of cubic ZnS microspheres exhibiting broad visible emission for bioimaging applications.
Biocompatible ZnS microspheres with an average diameter of 3.85 µm were grown by solvo-hydrothermal (S-H) method using water-acetonitrile-ethylenediamine (EDA) solution combination. ZnS microspheres were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), Fourier transform (FT)-Raman spectroscopy and Fourier transform infrared spectroscopy (FTIR) techniques. The broad photoluminescence (PL) emissions from 380-580 nm that were seen from the ZnS microspheres attributed to the increase in carrier concentration, as understood from the observed intense Raman band at 257 cm(-1). Cytotoxicity and haemocompatibility investigations of these ZnS microspheres revealed its biocompatibility. ZnS microspheres, along with biological cell lines, were giving visible light emission and could be used for bioimaging applications.
Nano Functional Materials Laboratory, Department of Physics, Cochin University of Science and Technology, Kochi, Kerala, 682022, India.
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Sajan
Biophotonics and Imaging Laboratory, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences & Technology, Poojappura, Thiruvananthapuram, 695012, Kerala, India.
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Jayasree
Departamento de Fisica Aplicada y Electromagnetismo, Universitat de, Valencia, C/Dr Moliner 50 Burjassot, Valencia, 46100, Spain.
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Agouram
Nano Functional Materials Laboratory, Department of Physics, Cochin University of Science and Technology, Kochi, Kerala, 682022, India.
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Junaid Bushiri
D000097:Acetonitriles / Q000737:chemistry; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D005029:Ethylenediamines / Q000737:chemistry; D008027:Light; D049449:Luminescence; D008863:Microspheres; D057054:Molecular Imaging / Q000379:methods*; D010316:Particle Size; D055668:Photochemical Processes; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry; D013499:Surface Properties; D013696:Temperature; D014867:Water / Q000737:chemistry; D017967:Zinc Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D000097:Acetonitriles; D001672:Biocompatible Materials; D005029:Ethylenediamines; D013440:Sulfides; D017967:Zinc Compounds; D014867:Water; C031234:ethylenediamine; C031238:zinc sulfide; C032159:acetonitrile
ZnS microspheres; bioimaging; broad visible emission; cytotoxicity; haemocompatibility; luminescence