Steroidogenesis in plants--Biosynthesis and conversions of progesterone and other pregnane derivatives.
In plants androstanes, estranes, pregnanes and corticoids have been described. Sometimes 17β-estradiol, androsterone, testosterone or progesterone were summarized as sex hormones. These steroids influence plant development: cell divisions, root and shoot growth, embryo growth, flowering, pollen tube growth and callus proliferation. First reports on the effect of applicated substances and of their endogenous occurrence date from the early twenties of the last century. This caused later on doubts on the identity of the compounds. Best investigated is the effect of progesterone. Main steps of the progesterone biosynthetic pathway have been analyzed in Digitalis. Cholesterol-side-chain-cleavage, pregnenolone and progesterone formation as well as the stereospecific reduction of progesterone are described and the corresponding enzymes are presented. Biosynthesis of androstanes, estranes and corticoids is discussed. Possible progesterone receptors and physiological reactions on progesterone application are reviewed.
Institut für Pharmazie, Martin-Luther Universität Halle/Wittenberg, Hoher Weg 8, 06120 Halle, Germany. Electronic address: Peter.lindemann@pharmazie.uni-halle.de.
Peter
P
Lindemann
D063245:Plant Development; D010937:Plant Growth Regulators / Q000378:metabolism*; D018521:Plant Physiological Phenomena; D010944:Plants / Q000378:metabolism*; D011278:Pregnanes / Q000378:metabolism*; D011374:Progesterone / Q000378:metabolism*
D010937:Plant Growth Regulators; D011278:Pregnanes; D011374:Progesterone
3-Beta-dehydrogenase; Ketosteroidisomerase; MSBP1; Progesterone-5-alpha-reductase; Progesterone-5-beta-reductase; Side-chain-cleavage