Acute eosinophilic pneumonia associated with glyphosate-surfactant exposure.
We report a case of a female patient who developed acute eosinophilic pneumonia (AEP) after recent onset of smoking and exposure to glyphosate-surfactant.The additional exposure associated with the recent start of smoking may have contributed to the development and/or severity of AEP.A clinical relapse after re-challenge four years later both with smoking and glyphosate-surfactant made the association highly likely.Respiratory distress is a factor of poor outcome and mortality after ingestion of glyphosate-surfactant.This case highlights the importance of a thorough exposure history e.g., possible occupational and environmental exposures together with drug-intake.Genotyping should be considered in cases of severe unexplained pulmonary damage.
ild care foundation research team, Ede, The Netherlands. w.deraadt@hetnet.nl.
Wanda M
WM
De Raadt
Petal A
PA
Wijnen
Aalt
A
Bast
Otto
O
Bekers
Marjolein
M
Drent
D000208:Acute Disease; D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D005998:Glycine / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D008991:Monitoring, Physiologic; D061330:Multidetector Computed Tomography / Q000379:methods; D011379:Prognosis; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis*; D013902:Radiography, Thoracic / Q000379:methods; D018570:Risk Assessment; D012907:Smoking / Q000009:adverse effects; D013501:Surface-Active Agents / Q000009:adverse effects*; D000097797:Glyphosate
D005998:Glycine; D013501:Surface-Active Agents; D000097797:Glyphosate