N-Heterocyclic Carbene-Palladium(II)-1-Methylimidazole Complex Catalyzed Direct C-H Bond Arylation of Benzo[b]furans with Aryl Chlorides.
The first example of sole direct C-H bond arylation of benzo[b]furans with aryl chlorides was achieved catalyzed by a well-defined NHC-Pd(II)-Im complex. Under the suitable conditions, all reactions involving kinds of benzo[b]furans and (hetero)aryl chlorides proceeded well to give the desired C2-arylated benzo[b]furans in sole regioselectivity in acceptable to high yields, providing an efficient and economic pathway for the direct C2-H bond arylation of benzo[b]furans.
College of Chemistry and Materials Engineering, Wenzhou University , Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China.
Shun-Chao
SC
Yin
College of Chemistry and Materials Engineering, Wenzhou University , Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China.
Quan
Q
Zhou
College of Chemistry and Materials Engineering, Wenzhou University , Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China.
Xiao-Yun
XY
Zhao
College of Chemistry and Materials Engineering, Wenzhou University , Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China.
Li-Xiong
LX
Shao