Genetic population study of Y-chromosome markers in Benin and Ivory Coast ethnic groups.
Ninety-six single nucleotide polymorphisms (SNPs) and seventeen short tandem repeat (STRs) were investigated on the Y-chromosome of 288 unrelated healthy individuals from populations in Benin (Bariba, Yoruba, and Fon) and the Ivory Coast (Ahizi and Yacouba). We performed a multidimensional scaling analysis based on FST and RST genetic distances using a large extensive database of sub-Saharan African populations. There is more genetic homogeneity in Ivory Coast populations compared with populations from Benin. Notably, the Beninese Yoruba are significantly differentiated from neighbouring groups, but also from the Yoruba from Nigeria (FST>0.05; P<0.01). The Y-chromosome dataset presented here provides new valuable data to understand the complex genetic diversity and human male demographic events in West Africa.
Evolutionary Medicine Group, Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse, UMR 5288, Centre National de la Recherche Scientifique (CNRS), Université Toulouse 3-Paul-Sabatier, Toulouse, France.
Cesar
C
Fortes-Lima
Leiden University Center for Linguistics, Leiden, the Netherlands.
Nicolas
N
Brucato
Section of Evolutionary Biology, Department of Biology II, University of Munich, 82152 Planegg-Martinsried, Germany.
Myriam
M
Croze
Institut National d'Etudes Démographiques, Paris, France.
Gil
G
Bellis
Evolutionary Medicine Group, Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse, UMR 5288, Centre National de la Recherche Scientifique (CNRS), Université Toulouse 3-Paul-Sabatier, Toulouse, France.
Stephanie
S
Schiavinato
Centre d'Etude et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance, Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Cotonou, Bénin.
Achille
A
Massougbodji
Centre d'Etude et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance, Faculté des Sciences de la Santé, Université d'Abomey-Calavi, Cotonou, Bénin; Institut de Recherche pour le Développement, UMR 216 Mère et enfant face aux infections tropicales, 4 avenue de l'Observatoire, 75006 Paris, France; COMUE Sorbonne Paris Cité, Université Paris Descartes, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France.
Florence
F
Migot-Nabias
Evolutionary Medicine Group, Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse, UMR 5288, Centre National de la Recherche Scientifique (CNRS), Université Toulouse 3-Paul-Sabatier, Toulouse, France. Electronic address: jean-michel.dugoujon@univ-tlse3.fr.
Jean-Michel
JM
Dugoujon
D001541:Benin; D041322:Chromosomes, Human, Y; D007560:Cote d'Ivoire; D005006:Ethnicity / Q000235:genetics*; D005819:Genetic Markers; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics; D020641:Polymorphism, Single Nucleotide
D005819:Genetic Markers
Benin; Genetic diversity; Ivory Coast; West Africa; Y-SNPs; Y-STRs