Multiple apocrine poromas: a new case report.
Apocrine poromas are rare and distinctive benign adnexal neoplasms featuring tumor cells differentiating toward folliculosebaceous-apocrine units. We report an extremely rare case with multiple apocrine poromas in a single patient. Fifteen tumors were distributed on the head, neck, forearm and axilla of a 74-year-old man. All tumors were mostly composed of poroid cells that surrounded variably sized duct spaces, some of which exhibited decapitation secretion. The poroid cells were continuous with infundibulum-like structures that contained aggregates of mature sebocytes. The patient had no family history of similar tumors and no history of immunosuppressive therapy. This is the first report of multiple apocrine poromas, suggesting that predisposing genetic factors might play a part in the development of the tumors.
Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Mina
M
Nishioka
Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Makoto
M
Kunisada
Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Norihiro
N
Fujiwara
Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Masahiro
M
Oka
Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Yoko
Y
Funasaka
Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.
Chikako
C
Nishigori
D000368:Aged; D001050:Apocrine Glands / Q000378:metabolism / Q000473:pathology*; D015415:Biomarkers / Q000378:metabolism; D002280:Basal Cell Carcinoma / Q000378:metabolism / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D053552:Keratin-7 / Q000378:metabolism; D007633:Keratins / Q000378:metabolism; D008297:Male; D057091:Poroma / Q000378:metabolism / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000378:metabolism / Q000473:pathology*
D015415:Biomarkers; C400901:CAM 5.2 antigen; D053552:Keratin-7; D007633:Keratins
cutaneous neoplasm; dermatopathology; skin tumors