Hydrophobic Ambivalence: Teetering on the Edge of Randomness.
Processes ranging from oil-water phase separation to the formation of solid clathrate hydrates send mixed messages regarding whether oil molecules hate or love to be surrounded by water. Recent experimental and theoretical results help decipher these mixed messages by illuminating the conditions under which the stability of a hydrophobic contact is expected to exceed thermal energy fluctuations - thus facilitating hydrophobic self-assembly and the emergence of structure from randomness. Important open questions remain regarding the dependence of hydrophobic interactions on molecular size and temperature, as well as the balance of direct and water-mediated interactions.
Purdue University, Department of Chemistry, West Lafayette, Indiana 47907, United States.
Dor
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Ben-Amotz
D057927:Hydrophobic and Hydrophilic Interactions; D015394:Molecular Structure; D013696:Temperature