[Progress in application of mesenchymal stem cells for nasal inflammation disease].
Mesenchymal stem cells (MSCs) are adult stem cells which derived from the embryonic mesoderm. They have a high proliferative ability and can differentiate into various tissues of mesodermal origin including bone, cartilage and adipose tissue in vitro. Moreover, MSCs have also been shown to produce anti-inflammatory molecules which can modulate cellular and humoral immune responses. Because of their easy preparation, the capacity for self-renewal, multi-lineage differentiation and immunoregulatory effect, MSCs therapy becomes a promising tool in the treatment of tissue regeneration, anti-inflammation, and autoimmune diseases. In this review we will focus on the application of MSCs for nasal inflammation disease.
Zhibang
Z
Hu
Xia
X
Gao
D053687:Adult Stem Cells / Q000637:transplantation*; D001327:Autoimmune Diseases; D002454:Cell Differentiation; D006801:Humans; D007249:Inflammation / Q000628:therapy*; D045164:Mesenchymal Stem Cell Transplantation; D008648:Mesoderm / Q000166:cytology; D009668:Nose Diseases / Q000628:therapy*; D014945:Wound Healing