Boosting the Quantitative Inorganic Surface-Enhanced Raman Scattering Sensing to the Limit: The Case of Nitrite/Nitrate Detection.
A high-performance ionic-sensing platform has been developed by an interdisciplinary approach, combining the classical colorimetric Griess reaction and new concepts of nanotechnology, such as plasmonic coupling of nanoparticles and surface-enhanced Raman scattering (SERS) spectroscopy. This approach exploits the advantages of combined SERS/surface-enhanced resonant Raman Scattering (SERRS) by inducing the formation of homogeneous hot spots and a colored complex in resonance with the laser line, to yield detection limits for nitrite down to the subpicomolar level. The performance of this new method was compared with the classical Griess reaction and ionic chromatography showing detection limits about 6 and 3 orders of magnitude lower, respectively.
†Departamento de Química Física, Biomedical Research Center (CINBIO) and Institute of Biomedical Research of Vigo (IBIV), Universidade de Vigo, 36310 Vigo, Spain.
Miguel A
MA
Correa-Duarte
‡Departamento de Química Física e Inorgánica, Universitat Rovira i Virgili and Centro Tecnologico de la Quimica de Cataluña, Carrer de Marcel·lí Domingo s/n, 43007 Tarragona, Spain.|§Medcom Advance SA, Viladecans Bussines Park, Carrer de Bertran i Musitu, 83-85, 08840 Viladecans (Barcelona), Spain.
Nicolas
N
Pazos Perez
‡Departamento de Química Física e Inorgánica, Universitat Rovira i Virgili and Centro Tecnologico de la Quimica de Cataluña, Carrer de Marcel·lí Domingo s/n, 43007 Tarragona, Spain.|§Medcom Advance SA, Viladecans Bussines Park, Carrer de Bertran i Musitu, 83-85, 08840 Viladecans (Barcelona), Spain.
Luca
L
Guerrini
∥Department of Physics, Imperial College, London SW7 2AZ, U.K.
Vincenzo
V
Giannini
‡Departamento de Química Física e Inorgánica, Universitat Rovira i Virgili and Centro Tecnologico de la Quimica de Cataluña, Carrer de Marcel·lí Domingo s/n, 43007 Tarragona, Spain.|§Medcom Advance SA, Viladecans Bussines Park, Carrer de Bertran i Musitu, 83-85, 08840 Viladecans (Barcelona), Spain.|⊥ICREA, Passeig Lluís Companys 23, 08010 Barcelona, Spain.
Ramon A
RA
Alvarez-Puebla
D053768:Metal Nanoparticles / Q000737:chemistry*; D008958:Models, Molecular; D009566:Nitrates / Q000737:chemistry*; D009573:Nitrites / Q000737:chemistry*; D013059:Spectrum Analysis, Raman / Q000379:methods*
D009566:Nitrates; D009573:Nitrites
Griess reaction; hot spots; inorganic ions; nanoparticles; optical sensors