The Influence of Genome and Cell Size on Brain Morphology in Amphibians.
In amphibians, nerve cell size is highly correlated with genome size, and increases in genome and cell size cause a retardation of the rate of development of nervous (as well as nonnervous) tissue leading to secondary simplification. This yields an inverse relationship between genome and cell size on the one hand and morphological complexity of the tectum mesencephali as the main visual center, the size of the torus semicircularis as the main auditory center, the size of the amphibian papilla as an important peripheral auditory structure, and the size of the cerebellum as a major sensorimotor center. Nervous structures developing later (e.g., torus and cerebellum) are more affected by secondary simplification than those that develop earlier (e.g., the tectum). This effect is more prominent in salamanders and caecilians than in frogs owing to larger genome and cells sizes in the former two taxa. We hypothesize that because of intragenomic evolutionary processes, important differences in brain morphology can arise independently of specific environmental selection.
University of Bremen, Brain Research Institute, D-283345 Bremen, Germany.
Gerhard
G
Roth
University of Cologne, Biocenter, Institute for Zoology, D-50674 Köln, Germany.
Wolfgang
W
Walkowiak
D000663:Amphibians / Q000033:anatomy & histology* / Q000235:genetics*; D000818:Animals; D001921:Brain / Q000033:anatomy & histology* / Q000166:cytology*; D016678:Genome