Seven Conformers of Neutral Dopamine Revealed in the Gas Phase.
The rotational spectrum of neutral dopamine has been investigated for the first time using a combination of Fourier transform microwave spectroscopy with laser ablation. The parameters extracted from the analysis of the spectrum unequivocally identify the existence of seven conformers of dopamine. (14)N nuclear quadrupole coupling interactions have been used to determine the orientation of the amino group probing the existence of stabilizing N-H···π interactions for all observed conformers.
Grupo de Espectroscopı́a Molecular (GEM), Edificio Quifima, Laboratorios de Espectroscopia y Bioespectroscopia, Parque Cientı́fico UVa, Universidad de Valladolid, 47005 Valladolid, Spain.
Carlos
C
Cabezas
Grupo de Espectroscopı́a Molecular (GEM), Edificio Quifima, Laboratorios de Espectroscopia y Bioespectroscopia, Parque Cientı́fico UVa, Universidad de Valladolid, 47005 Valladolid, Spain.
Isabel
I
Peña
Grupo de Espectroscopı́a Molecular (GEM), Edificio Quifima, Laboratorios de Espectroscopia y Bioespectroscopia, Parque Cientı́fico UVa, Universidad de Valladolid, 47005 Valladolid, Spain.
Juan C
JC
López
Grupo de Espectroscopı́a Molecular (GEM), Edificio Quifima, Laboratorios de Espectroscopia y Bioespectroscopia, Parque Cientı́fico UVa, Universidad de Valladolid, 47005 Valladolid, Spain.
José L
JL
Alonso
catecholamines; conformational analysis; laser ablation; microwave spectroscopy; nuclear quadrupole coupling interactions