Primary pulmonary leiomyosarcoma of lung: An unusual entity with brief review.
Primary pulmonary leiomyosarcomas are rare and diagnostically challenging group of neoplasms approximately constituting 0.2-0.5% of all primary lung malignancies. They originate from the smooth muscle cells of the bronchial wall, blood vessels or from the pulmonary interstitium. Here we present a case of 45 year old male with history of chronic cough, breathlessness and chest pain for few months. Clinical and radiological workup showed a left upper lobe lung mass. Endobronchial ultrasound guided (EUS) needle biopsy of the mass on histopathology confirmed leiomyosarcoma. Further through evaluation ruled out the possibility of metastasis. A final diagnosis of primary leiomyosarcoma of lung was made and patient was planned for surgical management.
Devajit
D
Nath
Department of Pathology, AIIMS, New Delhi, India.
Sudheer
S
Arava
Prashant
P
Joshi
Karan
K
Madan
Sandeep
S
Mathur
D000199:Actins / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001999:Bronchoscopy; D003893:Desmin / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000032:analysis; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000473:pathology*; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
D000199:Actins; D014408:Biomarkers, Tumor; D003893:Desmin; D019394:Ki-67 Antigen