Cancer-Related Fatigue, Version 2.2015.
Cancer-related fatigue is defined as a distressing, persistent, subjective sense of physical, emotional, and/or cognitive tiredness or exhaustion related to cancer or cancer treatment that is not proportional to recent activity and interferes with usual functioning. It is one of the most common side effects in patients with cancer. Fatigue has been shown to be a consequence of active treatment, but it may also persist into posttreatment periods. Furthermore, difficulties in end-of-life care can be compounded by fatigue. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Cancer-Related Fatigue provide guidance on screening for fatigue and recommendations for interventions based on the stage of treatment. Interventions may include education and counseling, general strategies for the management of fatigue, and specific nonpharmacologic and pharmacologic interventions. Fatigue is a frequently underreported complication in patients with cancer and, when reported, is responsible for reduced quality of life. Therefore, routine screening to identify fatigue is an important component in improving the quality of life for patients living with cancer.
Ann M
AM
Berger
Kathi
K
Mooney
Amy
A
Alvarez-Perez
William S
WS
Breitbart
Kristen M
KM
Carpenter
David
D
Cella
Charles
C
Cleeland
Efrat
E
Dotan
Mario A
MA
Eisenberger
Carmen P
CP
Escalante
Paul B
PB
Jacobsen
Catherine
C
Jankowski
Thomas
T
LeBlanc
Jennifer A
JA
Ligibel
Elizabeth Trice
ET
Loggers
Belinda
B
Mandrell
Barbara A
BA
Murphy
Oxana
O
Palesh
William F
WF
Pirl
Steven C
SC
Plaxe
Michelle B
MB
Riba
Hope S
HS
Rugo
Carolina
C
Salvador
Lynne I
LI
Wagner
Nina D
ND
Wagner-Johnston
Finly J
FJ
Zachariah
Mary Anne
MA
Bergman
Courtney
C
Smith
D019468:Disease Management; D005221:Fatigue / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D009369:Neoplasms / Q000150:complications* / Q000628:therapy; D059039:Standard of Care