Idiopathic giant cell myocarditis in childhood: A case report.
Idiopathic giant cell myocarditis is a rare entity of unknown origin, which causes sudden death in more than half of the affected patients. It is rarely seen in childhood, and might result in death due to heart failure and ventricular arrhythmias. Idiopathic giant cell myocarditis is mostly diagnosed at autopsy incidentally. Here we present a rare case of childhood idiopathic giant cell myocarditis. A 10-year old boy found dead in his bed in the morning. Interview with family members revealed death the boy was in good health conditions apart from being overweight. At autopsy, external examination was completely normal. Internal examination revealed normal findings; the heart was 297g and macroscopically normal. No traces of any toxic agents detected in complete toxicological analyses. Areas characterized with granulomatous lesions, lymphocytes, histiocytes, and multinucleated giant cells were observed in myocardium at histopathological examination. No necrosis was observed in granulomatous areas. Tuberculosis was negative in the PCR assays. There were no signs indicative of fungal infection, and clinical status of the case was not compatible with the sarcoidosis. In this respect death was attributed to idiopathic giant cell myocarditis.
Ankara Group Administration of the Council of Forensic Medicine, Ankara, Turkey.
Sultan
S
Pehlivan
Hacettepe University Medical Faculty, Department of Forensic Medicine, Ankara, Turkey.
Ramazan
R
Akçan
Hacettepe University Medical Faculty, Department of Forensic Medicine, Ankara, Turkey. Electronic address: eyuprusen@gmail.com.
Eyup Ruşen
ER
Heybet
Ankara Group Administration of the Council of Forensic Medicine, Ankara, Turkey.
Mehmet
M
Cavlak
Department of Microbiology, Ankara Research and Training Hospital, Ankara, Turkey.
Ali
A
Pehlivan
D001344:Autopsy; D002423:Cause of Death; D002648:Child; D049429:Forensic Pathology / Q000379:methods*; D015726:Giant Cells / Q000473:pathology*; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000473:pathology*
Childhood; Idiopathic giant cell myocarditis; Sudden death