Impact of nocturnal hemodialysis on peripheral uremic neuropathy.
BACKGROUND
Uremic neuropathy is a common complication in patients with end stage kidney disease. Its pathogenesis has been attributed to accumulation of uremic toxins. Kidney transplantation has been the best therapeutic option.


METHODS
We describe a case of severe uremic peripheral neuropathy, which improved after conversion from a conventional renal replacement therapy to nocturnal hemodialysis.


CONCLUSIONS
Enhanced uremic control by intensive hemodialysis may contribute at least in part to clinical and neurophysiological improvements of uremic neuropathy.
Department of Internal Medicine, Division of Nephrology, University Health Network Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, M5G 2C4, Canada. s_ghazanshahi@yahoo.ca.
Sassan
S
Ghazan-Shahi
Department of Internal Medicine, Division of Nephrology, University Health Network Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, M5G 2C4, Canada. Timothy_KOH@ttsh.com.sg.
Timothy Jee Kam
TJ
Koh
Department of Internal Medicine, Division of Nephrology, University Health Network Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, M5G 2C4, Canada. Christopher.chan@uhn.ca.
Christopher T
CT
Chan
D006437:Hemodialysis, Home / Q000379:methods*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000209:etiology / Q000628:therapy*; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000379:methods*; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D014511:Uremia / Q000150:complications / Q000628:therapy*