THE ASSOCIATION BETWEEN PRE-PREGNANCY OBESITY AND WEIGHT GAIN IN PREGNANCY, WITH GROWTH DEVIATIONS IN NEWBORNS.
BACKGROUND
obesity in pregnancy has been associated with increased morbidity for the mother and fetus.


OBJECTIVE
to quantify the association between obesity in pregnancy with growth deviations of their newborn infants.


METHODS
a study of non-matched cases and controls was performed based on the Nuevo Civil Hospital of Guadalajara "Dr. Juan I Menchaca" 2012-2013. The dependent variables were the newborn being either large (LGA) or small for gestational age (SGA), and the independent variable was pre-pregnancy obesity. Gynecoobstetric and socioeconomic data were collected. The association between the dependent and independent variables was assessed with logistic regression.


RESULTS
one-hundred and forty-three mother-child dyads were studied with growth deviations of their newborn infants, and 137 mother-child dyads without growth deviations were studied. The age of the patients was 24.7 ± 6.3 vs. 24.0 ± 6.0 years, and the gestational age was 38 ± 1.2 vs. 38 ± 1.5. Factors associated with growth deviations were pre-pregnancy obesity (OR 2.65, 95% CI 1.29- 5.44), elevated weight gain during pregnancy (OR 1.98, 95% CI 1.04-3.76) and disease during pregnancy (OR 2.62, 95% CI 1.05-6.76). A multivariate model with the dependent variable LGA and associated covariates showed that pre-pregnancy obesity and high gestational weight gain were predictors of LGA (OR 2.43, 95% CI 1.10-5.40) and (OR 3.31, 95% CI 1.83-5.96).


CONCLUSIONS
in a population of young women with scarce economic resources, pre-pregnancy obesity and high weight gain during pregnancy were predictors of LGA.
Instituto de Nutrición Humana, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, (Jalisco).. jesusperezmolina@gmail.com.
Dennis
D
Camacho-Buenrostro
División de Pediatría, Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Guadalajara, (Jalisco). Departamento de Clínicas de la Reproducción Humana, Crecimiento y Desarrollo Infantil, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, (Jalisco).. jesusperezmolina@gmail.com.
J Jesús
JJ
Pérez-Molina
Instituto de Nutrición Humana, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, (Jalisco). División de Pediatría, Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Guadalajara, (Jalisco).. vasquez.garibay@gmail.com.
Edgar M
EM
Vásquez-Garibay
Departamento de Clínicas de la Reproducción Humana, Crecimiento y Desarrollo Infantil, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, (Jalisco). División de Ginecología y Obstetricia, Nuevo Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Guadalajara, (Jalisco), México.. jesusperezmolina@gmail.com.
J Guadalupe
JG
Panduro-Barón
D000886:Anthropometry; D015992:Body Mass Index; D016022:Case-Control Studies; D002657:Child Development; D015897:Comorbidity; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D009765:Obesity / Q000453:epidemiology*; D016017:Odds Ratio; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011297:Prenatal Exposure Delayed Effects; D012307:Risk Factors; D015430:Weight Gain