Isolated splenic metastasis in a patient with two distinct genitourinary malignancies.
Splenic metastasis is rare, occurring in 2.3%- 7.1% of cases, of which 95% are carcinomas.1 The lung is the most common primary tumor site (21% of cases), followed by the gastrointestinal system, breast, ovaries, and skin. In a retrospective study evaluating the clinical and pathological impact of splenic metastases during a 25-year period in China, it was found that about 5.3% of metastases were isolated splenic metastasis.2 Isolated splenic metastasis from kidney cancer is very rare and is often an incidental finding. Here we report a case with isolated splenic metastasis in a patient with both primary renal cell carcinoma and prostate cancer, which turned out to be metastatic renal cell carcinoma in the spleen.
Department of Internal Medicine, Albany Medical Center, Albany, New York, USA. Zhangl1@mail.amc.edu.
Lulu
L
Zhang
Division of Hematology-Oncology, Department of Internal Medicine, Stratton Veterans Affairs Medical Center, Albany, New York, USA.
Donald
D
Pasquale
Department of Surgery, Stratton Veterans Affairs Medical Center, Albany, New York, USA.
Maithao
M
Le
Department of Pathology, Stratton Veterans Affairs Medical Center, Albany, New York, USA.
Raina
R
Patel
Division of Hematology-Oncology, Department of Internal Medicine, Stratton Veterans Affairs Medical Center, Albany, New York, USA.
Syed
S
Mehdi
isolated spleen metastasis; renal cell carcinoma