Electron Transfer Mechanism in Helical Peptides.
Electrochemical studies of a set of ferrocene-labeled helical peptides of increasing length were carried out by forming self-assembled monolayers (SAMs) on gold electrodes. Electron transfer (ET) rates showed a very weakly distance dependent nature that has been interpreted as a result of a dynamically controlled tunneling mechanism. Specifically, the slow equilibrium between the α- and the 310 helical conformers in a SAM has been invoked, and the rate of formation of the more conductive 310 conformer has been proposed to be related to the ET rates observed.
Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C9, Canada.
Himadri Shekhar
HS
Mandal
Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C9, Canada.
Heinz-Bernhard
HB
Kraatz
helix; peptide