Two novel herbicide candidates affect Arabidopsis thaliana growth by inhibiting nitrogen and phosphate absorption.
Both 2-[(2,4-dichlorophenoxy)acetoxy](methy)lmethyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one (termed as IIa) and 2-[(4-chloro-2-methyl-phenoxy)-acetoxy](methyl)methyl-5,5-dimethyl-1,3,2-dioxaphosphinan-2-one (termed as IIr) are novel herbicide candidates that positively affect herbicidal activity via the introduction of a phosphorus-containing heterocyclic ring. This report investigated the mechanism of IIa and IIr on weed control in the model plant Arabidopsis thaliana at physiological, ultrastructural and molecular levels. IIa and IIr significantly inhibited the growth of A. thaliana and altered its root structure by inhibiting energy metabolism and lipid or protein biosynthesis. These compounds also significantly affected the absorption of nitrogen and phosphorus by down-regulating the transcripts of nitrate transporter-related genes, ammonium transporter-related genes and phosphorus transporter-related genes.
Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, China.
Chongchong
C
Sun
College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China.
Yujian
Y
Jin
Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Central China Normal University, Wuhan 430079, China.
Haifeng
H
He
Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Central China Normal University, Wuhan 430079, China.
Wei
W
Wang
Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Central China Normal University, Wuhan 430079, China.
Hongwu
H
He
College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China.
Zhengwei
Z
Fu
Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, China; College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address: hfqian@zjut.edu.cn.
Haifeng
H
Qian
D027321:Anion Transport Proteins / Q000378:metabolism; D017360:Arabidopsis / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D015536:Down-Regulation; D006540:Herbicides; D000091285:Nitrate Transporters; D009584:Nitrogen / Q000378:metabolism*; D010758:Phosphorus / Q000378:metabolism*; D018517:Plant Roots / Q000378:metabolism; D058728:Weed Control
D027321:Anion Transport Proteins; D006540:Herbicides; D000091285:Nitrate Transporters; D010758:Phosphorus; D009584:Nitrogen
Gene transcript; Herbicide; N and P absorption; Ultrastructure