Bridging the Gap from Bench to Bedside - An Informatics Infrastructure for Integrating Clinical, Genomics and Environmental Data (ICGED).
The abundance of heterogeneous biomedical data from a variety of sources demands the development of strategies to address data integration and management issues, so that the data can be used effectively in clinical practices and biomedical research. This research presents an Informatics Infrastructure for Integrating Clinical, Genomics and Environmental Data (ICGED) and provides a roadmap that envisions utilizing the clinical and biomedical resources in our case study. This work describes a data integration approach, proposed by ICGED, with a two-fold purpose: personalized medicine and biomedical data storage and sharing platform. It describes our experiences integrating disease specific clinical and genomics datasets with Data Integration and Analysis Tools (DIAT)--using Informatics for Integrating Biology and the Bedside, and discusses work in progress and future work for extending DIAT, and the development of Risk Assessment and Prediction Tools, Clinical Decision Support Systems and a Bioinformatics Data Warehouse.
King Abdullah International Medical Research Center (KAIMRC), National Guard Health Affairs (NGHA), Riyadh, Saudi Arabia
Mohyuddin
D003628:Database Management Systems / Q000458:organization & administration*; D030541:Databases, Genetic; D066264:Datasets as Topic; D020000:Decision Support Systems, Clinical / Q000458:organization & administration; D057286:Electronic Health Records / Q000458:organization & administration*; D004784:Environmental Monitoring; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D023281:Genomics / Q000458:organization & administration; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods; D008498:Medical Record Linkage / Q000379:methods; D057285:Precision Medicine / Q000379:methods*; D018511:Systems Integration