title: Histocytological specificities of adrenal cortex in the New World Monkeys, Aotus lemurinus and Saimiri boliviensis.
abstract: The New World monkey Aotus spp. (night monkeys) are expected for use of valuable experimental animal with the close species of Saimiri spp. (squirrel monkeys). Saimiri is known to show spontaneous hypercortisolemia, although few reports in Aotus. We compared basic states of blood steroid hormones and histological structure of the adrenal glands in two monkeys. Serum cortisol and ACTH levels were statistically lower in Aotus than Saimiri. Conversely, Aotus adrenocortical area showed significant enlargement, especially at the zona fasciculata. Electron microscopic observation at Aotus fasciculata cells revealed notable accumulation of large lipid droplets and irregular shapes of the mitochondrial cristae. These results suggest potential differences in cellular activities for steroidogenesis between Aotus and Saimiri and experimental usefulness in adrenocortical physiology and pathological models.
authors: Laboratory of Basic Veterinary Science, The United Graduate School of Veterinary Science, 1677-1 Yoshida, Yamaguchi 753-8515, Japan.
authors: Toru
authors: T
authors: Tachibana
authors: Ken Takeshi
authors: KT
authors: Kusakabe
authors: Sayuri
authors: S
authors: Osaki
authors: Takeshi
authors: T
authors: Kuraishi
authors: Shosaku
authors: S
authors: Hattori
authors: Midori
authors: M
authors: Yoshizawa
authors: Chieko
authors: C
authors: Kai
authors: Yasuo
authors: Y
authors: Kiso
mesh_terms: D000302:Adrenal Cortex / Q000033:anatomy & histology* / Q000166:cytology; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000818:Animals; D016645:Aotidae / Q000033:anatomy & histology* / Q000097:blood; D004958:Estradiol / Q000097:blood; D005260:Female; D006854:Hydrocortisone / Q000097:blood; D008854:Microscopy, Electron / Q000662:veterinary; D011374:Progesterone / Q000097:blood; D012453:Saimiri / Q000033:anatomy & histology* / Q000097:blood; D015383:Zona Fasciculata / Q000033:anatomy & histology / Q000166:cytology
chemical_list: D011374:Progesterone; D004958:Estradiol; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone