title: 99mTc(V)-DMSA SPECT-CT findings in a case of Gorham-Stout disease.
abstract: The Gorham-Stout disease is a very rare condition, characterized by lymphovascular proliferation and massive bone resorption. We present a 48-year-old male patient with osteolysis involving the left femoral head and neck, as well as to the ipsilateral acetabulum. Besides the morphological imaging, he underwent bone scintigraphy, technetium-99m-V-dimercaptosuccinic acid [99mTc(V)-DMSA] single photon emission computed tomography/computed tomography (SPECT/CT) and histological examination. Together these findings gave the definitive diagnosis. This is the first case ever published with 99mTc(V)-DMSA SPECT-CT. Advances on the knowledge of disease suggests that this imaging procedure could have utility in diagnosis and evaluation of the disease activity and therapy response.
authors: Department of Nuclear Medicine, São João Hospital Center, Porto, Portugal. victor_alves@outlook.pt.
authors: Victor M
authors: VM
authors: Alves
authors: Tiago S
authors: TS
authors: Vieira
authors: Nelson S
authors: NS
authors: Amorim
authors: Ana
authors: A
authors: Oliveira
authors: André
authors: A
authors: Rodrigues
authors: Jorge G
authors: JG
authors: Pereira
mesh_terms: D005269:Femur / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D010015:Osteolysis, Essential / Q000000981:diagnostic imaging*; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D019783:Technetium Tc 99m Dimercaptosuccinic Acid