title: Effect of infant surgical orthopedic treatment on facial growth in preadolescent children with unilateral and bilateral complete cleft lip and palate.
abstract: OBJECTIVE
  To examine the impact of dentofacial infant orthopedic treatment (DFIO) on facial growth in preadolescent children with unilateral complete cleft lip and palate (UCCLP) and bilateral complete cleft lip and palate (BCCLP).
  
  
  METHODS
  This is a retrospective study of patients with UCCLP and BCCLP treated at a single center. The treatment group had DFIO, and the control group did not have DFIO. Regression models were used to compare outcomes between the study and control groups.
  
  
  RESULTS
  The study sample comprised 81 patients (54 had DFIO and 27 did not have DFIO). Among those with UCCLP, those who had DFIO had a shorter maxillary length (-2.12 mm; P = .04) and shorter lower anterior facial height (-2.77 mm; P = .04) compared with controls. Among those with BCCLP, there were no significant differences between the treatment and control groups.
  
  
  CONCLUSIONS
  DFIO treatment could result in shorter maxillary length and lower anterior facial height in those with UCCLP.
authors: Boston Children's Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA.
authors: Stephan P K
authors: SP
authors: Tan
authors: Department of Orthodontics, College of Dentistry, University of Iowa, Iowa City, Iowa, USA. Electronic address: Veerasathpurush-Allareddy@uiowa.edu.
authors: Veerasathpurush
authors: V
authors: Allareddy
authors: Boston Children's Hospital, Boston, Massachusetts, USA; Harvard School of Dental Medicine, Boston, Massachusetts, USA.
authors: Richard A
authors: RA
authors: Bruun
authors: Boston Children's Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA.
authors: John B
authors: JB
authors: Mulliken
authors: Division of Plastic and Reconstructive Surgery and Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA; Department of Plastic Surgery, Rhode Island Hospital, Providence, Rhode Island, USA; Hasbro Children's Hospital, Providence, Rhode Island, USA.
authors: Stephen R
authors: SR
authors: Sullivan
authors: Endodontist in private practice, Miami, Florida, USA.
authors: Oscar J
authors: OJ
authors: Peguero
authors: Orthodontist in private practice, Stockbridge, Georgia, USA.
authors: Justin S
authors: JS
authors: Cooper
authors: Boston Children's Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA; Harvard School of Dental Medicine, Boston, Massachusetts, USA.
authors: Bonnie L
authors: BL
authors: Padwa
authors: Gerlein Orthodontics, Chevy Chase, Maryland, USA.
authors: Eduardo J
authors: EJ
authors: Gerlein
authors: Harvard School of Public Health, Boston, Massachusetts, USA.
authors: E Francis
authors: EF
authors: Cook
authors: Boston Children's Hospital, Boston, Massachusetts, USA; Harvard School of Dental Medicine, Boston, Massachusetts, USA.
authors: Stephen
authors: S
authors: Shusterman
mesh_terms: D002508:Cephalometry; D002648:Child; D002675:Child, Preschool; D002971:Cleft Lip / Q000503:physiopathology / Q000601:surgery*; D002972:Cleft Palate / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008445:Maxillofacial Development; D019637:Orthopedic Procedures; D012189:Retrospective Studies