title: Discovery of Acupoints and Combinations with Potential to Treat Vascular Dementia: A Data Mining Analysis.
abstract: The prevalence of vascular dementia (VaD) is high among the elderly. Acupuncture, a popular therapeutic method in China, can improve memory, orientation, calculation, and self-managing ability in VaD patients. However, in clinical acupuncture and acupuncture research, the selection of acupoints to treat VaD remains challenging. This study aimed to discover acupoints and acupoint combinations with potential for VaD based on data mining. After database searching and screening for articles on clinical trials evaluating the effects of acupuncture on VaD, 238 acupuncture prescriptions were included for further analysis. Baihui (GV 20), Sishencong (EX-HN 1), Fengchi (GB 20), Shuigou (GV 26), and Shenting (GV 24) appeared most frequently in the modern literature and are potential acupoints for VaD. Combinations between Baihui (GV 20), Sishencong (EX-HN 1), Fengchi (GB 20), Shenting (GV 24), Shuigou (GV 26), and Zusanli (ST 36) were most frequent and represent potential combinations for VaD treatment. These results provide a reference for the selection and combination of acupoints to treat VaD in clinical acupuncture and acupuncture research.
authors: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors: Shuwei
authors: S
authors: Feng
authors: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors: Yulan
authors: Y
authors: Ren
authors: Southwest Petroleum University, Chengdu, Sichuan 610500, China.
authors: Shilin
authors: S
authors: Fan
authors: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors: Minyu
authors: M
authors: Wang
authors: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors: Tianxiao
authors: T
authors: Sun
authors: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors: Fang
authors: F
authors: Zeng
authors: Southwest Petroleum University, Chengdu, Sichuan 610500, China.
authors: Ping
authors: P
authors: Li
authors: Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610075, China.
authors: Fanrong
authors: F
authors: Liang