title: Spontaneous regression of intracranial aneurysm following remote ruptured aneurysm treatment with pipeline stent assisted coiling.
abstract: Spontaneous aneurysm regression is a rare phenomenon. We present the interesting case of a 54-year-old woman who was admitted with a Hunt/Hess grade IV, Fisher grade III subarachnoid hemorrhage and multiple intracranial aneurysms. She was treated with coiling of the largest paraclinoid aneurysm and placement of a flow diverting pipeline embolization device that covered all internal carotid artery (ICA) aneurysms. A follow-up angiogram at 6 months showed remodeling of the ICA with complete obliteration of all treated aneurysms. A distant, untreated, right frontal M2 aneurysm regressed spontaneously, after the flow was diverted away from it with the stent. The literature is reviewed, and potential pathophysiological mechanisms leading to aneurysm regression are discussed.
authors: Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, USA.
authors: Asterios
authors: A
authors: Tsimpas
authors: Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, USA.
authors: William W
authors: WW
authors: Ashley
authors: Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, USA.
authors: Anand V
authors: AV
authors: Germanwala
mesh_terms: D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000601:surgery*; D000792:Angiography; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000601:surgery; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012075:Remission, Spontaneous; D015607:Stents; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D010975:Platelet Aggregation Inhibitors
keywords: Aneurysm; Angiography; Coil; Flow Diverter; Subarachnoid