title: Hypertension in the African American population: A succinct look at its epidemiology, pathogenesis, and therapy.
abstract: Arterial hypertension is prevalent in the black population in the United States. It is directly related to cardiovascular and kidney damage. Its pathogenesis is complex and includes the high incidence of obesity, salt sensitivity and the activation of the renin-angiotensin-aldosterone system. This complexity requires a therapeutic combination that includes changes in dietary habits and appropriate antihypertensive regimes. The International Society of Hypertension in Blacks recommends initiating dietary intervention for values of systolic/diastolic arterial blood pressure above 115/75 mmHg and maintaining arterial blood pressure below 135/85 mmHg using appropiate antihypertensive medication. The most adequate antihypertensive drug for this population has yet to be determined.
authors: Division of Nephrology and Hypertension. Allegheny General Hospital/Temple University School of Medicine. Pittsburgh, Pennsylvania (Estados Unidos). Electronic address: lortega@wpahs.org.
authors: Luis M
authors: LM
authors: Ortega
authors: Division of Nephrology and Hypertension. Allegheny General Hospital/Temple University School of Medicine. Pittsburgh, Pennsylvania (Estados Unidos).
authors: Emad
authors: E
authors: Sedki
authors: Division of Nephrology and Hypertension. University of Miami Miller School of Medicine. Miami, Florida (Estados Unidos).
authors: Ali
authors: A
authors: Nayer
mesh_terms: D001741:Black or African American / Q000706:statistics & numerical data; D000959:Antihypertensive Agents / Q000627:therapeutic use; D015897:Comorbidity; D004039:Diet, Sodium-Restricted; D004730:Endothelium, Vascular / Q000503:physiopathology; D005081:Exercise Therapy; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D006973:Hypertension / Q000208:ethnology* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D008297:Male; D009765:Obesity / Q000453:epidemiology; D015995:Prevalence; D012084:Renin-Angiotensin System / Q000502:physiology; D017673:Sodium Chloride, Dietary / Q000009:adverse effects; D014481:United States / Q000453:epidemiology
chemical_list: D000959:Antihypertensive Agents; D017673:Sodium Chloride, Dietary
keywords: African American; Afroamericanos; Americans; Antihipertensivos; Antihypertensives for African; Epidemiology of hypertension; Epidemiología de la hipertensión; Hipertensión; Hypertension; Pathogenesis of hypertension; Patogénesis de la hipertensión; para afroamericanos