title: Prevalence of and Risk Factors for Type 2 Diabetes Mellitus in Hyperlipidemia in China.
abstract: BACKGROUND
  We explored the prevalence of and risk factors for type 2 diabetes in the adult population of Shanghai (China) with and without dyslipidemia.
  
  
  METHODS
  We conducted a cross-sectional survey including 14 385 adults (aged 16 to 88 years) in Shanghai using a stratified, multistage cluster sampling approach.
  
  
  RESULTS
  Type 2 diabetes and hyperlipidemia were found in 1456 (10.1%) and 4583 (31.9%) subjects, respectively. Type 2 diabetes was more common in males (11.4%) than in females (9.2%, P<0.01), in the elderly (> or =65 years, 22.5%) than in younger (<55 years, <10%, P<0.01) individuals, and in urban (12.8%) than in rural populations (5.2%, P<0.01). Diabetes incidence was higher among patients with hyperlipidemia than in controls (16.9% vs. 7.0%, P<0.01; OR=2.72, 95% CI 2.44-3.03). Compared with controls, the risk for diabetes in subjects with isolated hypertriglyceridemia, isolated hypercholesterolemia, and mixed hyperlipidemia increased 1.75-fold (95% CI 1.53-1.99), 1.53-fold (95% CI 1.17-2.01), and 2.93-fold (95% CI 2.37-3.63), respectively. The fasting plasma glucose (FPG) and 2h-postprandial plasma glucose (2h-PG) increased with age in both sexes. The age- and sex-adjusted FPG and 2h-PG levels in hyperlipidemia were significantly higher than in controls (P<0.01).
  
  
  CONCLUSIONS
  A high prevalence of type 2 diabetes in hyperlipidemia patients exists in Shanghai. Hyperlipidemia is associated with elevated blood glucose levels and therefore requires prompt intervention for prevention and treatment of diabetes in patients with dyslipidemia.
authors: Center for Fatty Liver Disease, Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (mainland).
authors: Guang-Yu
authors: GY
authors: Chen
authors: Department of Chronic Disease, Shanghai Center for Disease Control and Prevention, Shanghai, China (mainland).
authors: Lui
authors: L
authors: Li
authors: School of Public Health, Shanghai Jiao-Tong University School of Medicine, Shanghai, China (mainland).
authors: Fei
authors: F
authors: Dai
authors: Department of Chronic Disease, Shanghai Center for Disease Control and Prevention, Shanghai, China (mainland).
authors: Xing-Jian
authors: XJ
authors: Li
authors: Research Center for Clinical Epidemiology, Shanghai Jiao-Tong University School of Medicine, Shanghai, China (mainland).
authors: Xiao-Xin
authors: XX
authors: Xu
authors: Center for Fatty Liver Disease, Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (mainland).
authors: Jian-Gao
authors: JG
authors: Fan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology* / Q000209:etiology*; D005215:Fasting / Q000097:blood; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000150:complications; D006949:Hyperlipidemias / Q000097:blood / Q000150:complications*; D015228:Hypertriglyceridemia / Q000097:blood / Q000150:complications; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D019518:Postprandial Period; D015995:Prevalence; D012307:Risk Factors; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D008055:Lipids