title: Correlation of Physical Activities and Breast Cancer Characteristics: A Prospective Analysis with Special Focus on Triple Negative Breast Cancer.
abstract: OBJECTIVE
  Several studies have demonstrated that daily physical activity (PA) prevents the development of breast cancer. Our objective was to examine the relationship between PA and clinical and biological tumor characteristics in breast cancer patients in order to determine the impact of energy expenditure (EE) on tumor prognosis.
  
  
  METHODS
  We pooled data from two prospective studies, including a total of 121 breast cancer patients. The measure of PA was done using the self-completion Population Physical Activity Questionnaire, which was answered by each patient.
  
  
  RESULTS
  Ten patients harbored triple negative (TN) tumors. The mean body mass index (BMI) in the general population and in patients with TN tumors was 24.3 and 25.6, respectively. The mean daily EE (DEE) was 10,266 kJ×24 h(-1) in the general population and 11,212 kJ×24 h(-1) in patients with TN tumors. In the whole population, there was an inverse statistical correlation between BMI and DEE, rest, low PA, and high PA (p=0.0002, p=0.003, p<0001, and p=0.03, respectively). There was a positive correlation between negative estrogen receptor status and intensive PA (p=0.041) and DEE (p=0.007). For TN tumors, there was no significant correlation between BMI and categories of EE.
  
  
  CONCLUSIONS
  Lifestyle (weight regulation, PA) should be adapted and personalized according to biological, clinical, and epidemiological characteristics of the tumors.
authors: Dx00E9;partement de Radiothx00E9;rapie, Institut de Cancx00E9;rologie Lucien Neuwirth, Saint-Priest-en-Jarez, France.
authors: Alexis
authors: A
authors: Vallard
authors: Alexander Tuan
authors: AT
authors: Falk
authors: Pascale
authors: P
authors: Antoine
authors: Jean-Baptiste
authors: JB
authors: Guy
authors: Jean-Baptiste
authors: JB
authors: Guichard
authors: Sophie
authors: S
authors: Espenel
authors: Julien
authors: J
authors: Langrand-Escure
authors: Jane-Chloé
authors: JC
authors: Trone
authors: Benoîte
authors: B
authors: Méry
authors: Majed
authors: M
authors: Ben Mrad
authors: Peng
authors: P
authors: Diao
authors: Guoping
authors: G
authors: Wang
authors: Frédéric
authors: F
authors: Roche
authors: Claire
authors: C
authors: Bosacki
authors: Cyrus
authors: C
authors: Chargari
authors: Aurélie
authors: A
authors: Bourmaud
authors: Nicolas
authors: N
authors: Magné
mesh_terms: D015992:Body Mass Index; D005260:Female; D006801:Humans; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D011379:Prognosis; D011446:Prospective Studies; D011960:Receptors, Estrogen / Q000378:metabolism; D064726:Triple Negative Breast Neoplasms / Q000378:metabolism / Q000473:pathology*
chemical_list: D011960:Receptors, Estrogen