title: [Chosen anthropometric parameters and concentrations of leptin and adiponectin in extreme obese patients treated with implantation of a gastric balloon].
abstract: Fatty tissue derived adipocytokines regulate appetite, but in abnormal concentration impair systemic metabolic homeostasis and make the patients prone to inflammatory related disorders. The aim of study was to examine whether weight loss in patients after implementation of a gastric balloon is reflected in changes in chosen anthropometrical parameters and in the concentration of leptin and adiponectin in serum.
  
  
  METHODS
  The study group consisted of 18 extreme obese patients (BMI>39.9, mean age 39.5±12.1 years, 12 men, 6 women), undergoing implementation of a gastric balloon for 6 months. The control group consisted of 18 healthy volunteers. The adiponectin and leptin concentrations in the sera and the calculated % body fat and indicators: BMI, WHR, VAI, BAI, WHtR were determined prior to implementation and after the balloon removal and then further parameters were calculated: % excessive weight loss, % weight loss.
  
  
  CONCLUSIONS
  All the parameters and leptin concentration in the tested group were markedly upregulated and adiponectin concentration was significantly lower compared to controls. Reduction in the body mass in patients subjected to BIB, reflected in leptin and anthropometrical parameters down-regulation, (except WHR and VAI), was accompanied with normalization of adiponectin concentration that affect metabolism and is important regulator of hunger and satiety.
authors: Medical University of Lodz, Poland, Department of Pathophysiology and Clinical Immunology.
authors: Edyta
authors: E
authors: Blus
authors: PULSMED Medical Centre, Lodz, Poland.
authors: Zbigniew
authors: Z
authors: Kowalczyk
authors: PULSMED Medical Centre, Lodz, Poland.
authors: Agnieszka
authors: A
authors: Wojciechowska-Kulik
authors: Medical University of Lodz, Poland, Department of Pathophysiology and Clinical Immunology.
authors: Zbigniew
authors: Z
authors: Baj
authors: Medical University of Lodz, Poland, Department of Pathophysiology and Clinical Immunology.
authors: Ewa
authors: E
authors: Majewska
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000328:Adult; D000886:Anthropometry; D005260:Female; D015905:Gastric Balloon; D006801:Humans; D020738:Leptin / Q000097:blood*; D008297:Male; D009767:Obesity, Morbid / Q000097:blood* / Q000628:therapy*; D015854:Up-Regulation; D015431:Weight Loss
chemical_list: D052242:Adiponectin; D020738:Leptin
keywords: adiponectin; adipose tissue; anthropometric parameters; leptin; obesity