title: The Effect of Cumulative Dissipated Energy on Changes in Intraocular Pressure After Uncomplicated Cataract Surgery by Phacoemulsification.
abstract: To investigate the association between ultrasound energy, expressed as cumulative dissipated energy (CDE), and changes in intraocular pressure (IOP) after uncomplicated cataract surgery by phacoemulsification.
  
  
  
  In this prospective study, nonglaucomatous subjects underwent cataract surgery by phacoemulsification. IOP was compared by clustered linear regression at 4 separate time-points: preoperative, 1 day, 1 month, and 3 months after cataract surgery. Changes in the IOP were evaluated as a function of CDE using univariate and multivariate clustered linear regression models, which adjusted for sex, ethnicity, age, axial length, spherical equivalent, mean preoperative Shaffer gonioscopy grade of all 4 quadrants, cataract grade, preoperative IOP, central corneal thickness, and use of both eyes in the same subject.
  
  
  
  One hundred sixty-one eyes (89 Asian, 49 white, 12 African, and 11 Hispanic) from 116 nonglaucomatous subjects were analyzed. The 161 eyes included 81 right and 80 left eyes. The 89 Asian eyes included 46 Chinese, 35 Filipino, and 8 Vietnamese. Preoperative IOP was 14.9±3.2 mm Hg. Postoperative IOP significantly increased to 16.0±4.9 mm Hg at 1 day (P=0.037) and decreased to 12.4±3.1 and 12.3±3.0 mm Hg at 1 and 3 months, respectively (both P<0.0001). IOP changes at 1 day, 1 month, and 3 months did not demonstrate significant associations with CDE measurements in either univariate or multivariate clustered linear regression analyses (all P>0.05).
  
  
  
  The amount of ultrasound energy delivered to the eye during phacoemulsification, expressed as CDE, was not associated with postoperative changes in IOP.
authors: *Department of Ophthalmology, University of California San Francisco School of Medicine, San Francisco, CA †Wake Forest University School of Medicine, Winston-Salem, NC ‡Case Western Reserve University School of Medicine, Cleveland, OH §Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan.
authors: Roland Y
authors: RY
authors: Lee
authors: Rebecca I
authors: RI
authors: Chen
authors: Toshimitsu
authors: T
authors: Kasuga
authors: Qi N
authors: QN
authors: Cui
authors: Travis C
authors: TC
authors: Porco
authors: Shan C
authors: SC
authors: Lin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000150:complications; D005260:Female; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000295:instrumentation* / Q000379:methods; D011446:Prospective Studies; D014065:Tonometry, Ocular; D000069453:Ultrasonic Waves