title: Local infiltration analgesia versus standard analgesia in total knee arthroplasty.
abstract: OBJECTIVE
  To compare outcome and cost following local infiltration analgesia (LIA) versus standard analgesia in total knee arthroplasty (TKA).
  
  
  METHODS
  13 men and 33 women (mean age, 67.5 years) underwent TKA by a single surgeon and received LIA (n=24) or standard analgesia (n=22), depending on the availability of the senior anaesthetist.
  
  
  RESULTS
  The 2 groups were comparable at baseline in terms of age, gender, body mass index, American Society of Anesthesiologists score, and range of motion. Compared with the standard analgesia group, the LIA group resulted in a shorter mean length of hospital stay (4.9 vs. 2.7 days, p<0.0001) and higher proportion of patients able to straight leg raise on discharge (38% vs. 86%, p=0.0011), as well as lower pain scores in the first 3 days and greater range of motion at all time points. Respectively in the standard analgesia and LIA groups, the mean cost per patient for all analgesic medication was A$129.25 and A$153.63, the mean cost per patient for all nights spent in hospital was A$1600.36 and A$901.50, and thus the mean total cost per patient was A$1729.61 and A$1055.13.
  
  
  CONCLUSIONS
  Compared with standard analgesia, LIA results in greater pain relief and improvement in range of motion immediately after TKA, and lower hospital costs.
authors: Northside Training Program, Australia.
authors: Mayuran
authors: M
authors: Suthersan
authors: Lismore Base Hospital, Australia.
authors: Sabrina
authors: S
authors: Pit
authors: Lismore Base Hospital, Australia.
authors: Loris
authors: L
authors: Gordon
authors: Lismore Base Hospital, Australia.
authors: Mark
authors: M
authors: Loman
authors: Lismore Base Hospital, Australia.
authors: Brian
authors: B
authors: Pezzutti
authors: Lismore Base Hospital, Australia.
authors: Richard
authors: R
authors: Freihaut
mesh_terms: D000368:Aged; D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000639:trends; D008297:Male; D020370:Osteoarthritis, Knee / Q000503:physiopathology / Q000601:surgery*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000517:prevention & control*; D016059:Range of Motion, Articular; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local
keywords: analgesia; arthroplasty, replacement, knee; length of stay; pain, postoperative