title: The Use of a Combination Antibiogram to Assist with the Selection of Appropriate Antimicrobial Therapy for Carbapenemase-Producing Enterobacteriaceae Infections.
abstract: Combination antibiograms can be used to evaluate organism cross-resistance among multiple antibiotics. As combination therapy is generally favored for the treatment of carbapenemase-producing Enterobacteriaceae (CPE), combination antibiograms provide valuable information about the combination of antibiotics that achieve the highest likelihood of adequate antibiotic coverage against CPE.
authors: 1The Johns Hopkins Hospital,Department of Pharmacy,Baltimore,Maryland.
authors: Alice J
authors: AJ
authors: Hsu
authors: 2The Johns Hopkins Hospital,Department of Pathology and Medicine,Baltimore,Maryland.
authors: Karen C
authors: KC
authors: Carroll
authors: 3The Johns Hopkins University School of Medicine,Department of Pediatrics,Division of Pediatric Infectious Diseases,Baltimore,Maryland.
authors: Aaron M
authors: AM
authors: Milstone
authors: 1The Johns Hopkins Hospital,Department of Pharmacy,Baltimore,Maryland.
authors: Edina
authors: E
authors: Avdic
authors: 4The Johns Hopkins University School of Medicine,Department of Medicine,Division of Infectious Diseases,Baltimore,Maryland.
authors: Sara E
authors: SE
authors: Cosgrove
authors: 5Stevenson University,Baltimore,Maryland.
authors: Mercedes
authors: M
authors: Vilasoa
authors: 3The Johns Hopkins University School of Medicine,Department of Pediatrics,Division of Pediatric Infectious Diseases,Baltimore,Maryland.
authors: Pranita D
authors: PD
authors: Tamma
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015780:Carbapenems / Q000494:pharmacology*; D016208:Databases, Factual; D004359:Drug Therapy, Combination; D004755:Enterobacteriaceae / Q000187:drug effects*; D004756:Enterobacteriaceae Infections / Q000188:drug therapy; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems