title: Carbamate-catalyzed enantioselective bromolactamization.
abstract: A highly facile, efficient, and enantioselective bromolactamization of olefinic amides was effected by a carbamate catalyst and ethanol additive. The amide substrates underwent N-cyclization predominantly to give a diverse range of enantioenriched bromolactam products containing up to two stereogenic centers.
authors: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore).
authors: Yi An
authors: YA
authors: Cheng
authors: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore).
authors: Wesley Zongrong
authors: WZ
authors: Yu
authors: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore). chmyyy@nus.edu.sg.|Department of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong (China). chmyyy@nus.edu.sg.
authors: Ying-Yeung
authors: YY
authors: Yeung
keywords: asymmetric catalysis; cyclizations; lactams; organocatalysis; reaction mechanisms