title: Effects of Infrared Laser Radiation on theIn VitroIsomerization of All-TransRetinal to 11-CisRetinal.
abstract: Thein vitroeffect of infrared laser light on the isomerization of all-transretinal dissolved in an ether/hexane and also an ethanol solvent was studied. Pulsed laser energy at 1064 nm was used to drive the molecular reconfiguration of all-transretinal to 11-cisretinal. High pressure liquid chromatography (HPLC) was used to quantify the conversion. Overall isomerization was minimal (0.2 percent to 1.0 percent), yet, a significant difference in isomerization due to pulsed infrared laser energy over non-modulated monochromatic laser light was detected (up to 168 percent difference). Potentially, pulsed laser radiation tuned to the ethylenic stretch frequency of the C11=C12bond of retinal may induce rotational changes to the chromophore.
authors: Division of Life Sciences, The University of Texas at San Antonio, San Antonio, Texas 78285.
authors: J
authors: J
authors: Liegner
authors: Clinical Sciences Division, USAF School of Aerospace Medicine, Brooks AFB, San Antonio, Texas 78235.
authors: J
authors: J
authors: Taboada
authors: Division of Life Sciences, The University of Texas at San Antonio, San Antonio, Texas 78285.
authors: A T C
authors: AT
authors: Tsin
keywords: IR radiation; isomerization; retinal; vision