title: Short-term exposure to particulate air pollution and risk of myocardial infarction: a systematic review and meta-analysis.
abstract: A growing number of studies have associated short-term exposure to ambient particulate matter air pollution (PM) and risk of specific cardiovascular events, just as myocardial infarction (MI). However, the results of the recent studies were inconsistent; therefore, a systematic review and meta-analysis was performed. To synthetically quantify the association between short-term exposure to PM and risk of MI, a meta-analysis was conducted to combine the estimates of effect for a relationship between short-term exposure to PM10, PM2.5 (particulate matter ≤ 10 μm, 2.5 μm in diameter) and risk of MI. Electronic database searches for all relevant published studies were updated in January 2015. And, a random-effects model was performed to estimate pooled relative risk (RR) and 95 % confidence intervals (95 % CI). Thirty-one published observational epidemiological studies were identified. Risk of MI was significantly associated with per 10 μg/m(3) increment in PM10 (OR = 1.005; 95 % CI 1.001-1.008) and PM2.5 (OR = 1.022; 95 % CI 1.015-1.030). The risk of PM2.5 exposure was relatively greater than PM10. In the subgroup analysis by study design, location, quality score, and lag exposure, the results were basically consistent with the former overall results in PM2.5 but slightly changed in PM10. Short-term exposure to particulate matter (PM2.5, PM10) was a risk factor for MI, and the results further confirmed the discovery in the previous meta-analysis.
authors: Department of Cardiology Medical, The Second People's Hospital of Hefei, Heping Road, Hefei, Anhui, China.
authors: Chunmiao
authors: C
authors: Luo
authors: Department of Occupational and Environmental, School of Public Health, Anhui Medical University, Meishan Road, Hefei, Anhui, China.
authors: Xiaoxia
authors: X
authors: Zhu
authors: Department of Occupational and Environmental, School of Public Health, Anhui Medical University, Meishan Road, Hefei, Anhui, China.
authors: Cijiang
authors: C
authors: Yao
authors: Department of Occupational and Environmental, School of Public Health, Anhui Medical University, Meishan Road, Hefei, Anhui, China.
authors: Lijuan
authors: L
authors: Hou
authors: Department of Occupational and Environmental, School of Public Health, Anhui Medical University, Meishan Road, Hefei, Anhui, China.
authors: Jian
authors: J
authors: Zhang
authors: The Teaching Center for Preventive Medicine, School of Public Health, Anhui Medical University, Meishan Road, Hefei, Anhui, China.
authors: Jiyu
authors: J
authors: Cao
authors: Department of Cardiology Medical, the First Affiliated Hospital of Anhui Medical University, Jixi Road, Hefei, Anhui, China. chunguangchuxian66@163.com.
authors: Ailing
authors: A
authors: Wang
mesh_terms: D000397:Air Pollution; D004781:Environmental Exposure; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology*; D052638:Particulate Matter / Q000633:toxicity*; D012307:Risk Factors
chemical_list: D052638:Particulate Matter
keywords: Ambient particulate matter; Meta-analysis; Myocardial infarction; Short term