title: Nanotechnology approaches for inhalation treatment of lung diseases.
abstract: Local administration of therapeutics by inhalation for treatment of lung diseases has the ability to deliver drugs, nucleic acids and peptides specifically to the site of their action and therefore enhance the efficacy of the treatment, limit the penetration of nebulized therapeutic agent(s) into the bloodstream and consequently decrease adverse systemic side effects of the treatment. Nanotechnology allows for a further enhancement of the treatment efficiency. The present review analyzes modern therapeutic approaches of inhaled nanoscale-based pharmaceutics for the detection and treatment of various lung diseases.
authors: Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway 08854, USA.
authors: Andriy
authors: A
authors: Kuzmov
authors: Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway 08854, USA; Rutgers Cancer Institute of New Jersey, New Brunswick 08903, USA. Electronic address: minko@rci.rutgers.edu.
authors: Tamara
authors: T
authors: Minko
mesh_terms: D000280:Administration, Inhalation; D000818:Animals; D016503:Drug Delivery Systems; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy*; D036103:Nanotechnology; D004364:Pharmaceutical Preparations / Q000008:administration & dosage
chemical_list: D004364:Pharmaceutical Preparations
keywords: Fibrosis; Gene delivery; Hypoxia; Lung cancer; Nanoparticles; Pulmonary delivery