title: Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy.
abstract: We report the case of a 38-year-old man, who developed cutaneous metastases in the left inguinal groove 15 years after curative gastrectomy for advanced gastric adenocarcinoma. Histopathologic examination revealed poorly differentiated adenocarcinoma cells. They were stained positive for villin, CDX-2, CKpan (AE1/ AE3), CEA, CK8/18, CK19, CK7, EMA, Ki-67 (50%), and negative for S-100, CK20, CD34, GCDFP-15 and TTF-1. The patient underwent local excision, after the presence of other metastases was excluded. Nevertheless, local recurrence developed at the surgical bed one year later and PET/CT revealed metastases to lymph nodes, bone and skin. He died 2 years after the appearance of cutaneous metastases. We have reviewed the literature and described the immunohistochemical characteristics of cutaneous metastases from gastric adenocarcinoma.
authors: Department of Dermatology, Jinling Hospital affiliated to Nanjing University School of Medicine, Nanjing, CN.
authors: Fang
authors: F
authors: Liu
authors: Department of Dermatology, Jinling Hospital affiliated to Nanjing University School of Medicine, Nanjing, CN.
authors: Wen Liang
authors: WL
authors: Yan
authors: Department of Dermatology, Jinling Hospital affiliated to Nanjing University School of Medicine, Nanjing, CN.
authors: Haibo
authors: H
authors: Liu
authors: Department of Dermatology, Jinling Hospital affiliated to Nanjing University School of Medicine, Nanjing, CN.
authors: Min
authors: M
authors: Zhang
authors: Department of Dermatology, Jinling Hospital affiliated to Nanjing University School of Medicine, Nanjing, CN.
authors: Hong
authors: H
authors: Sang
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D017809:Fatal Outcome; D005743:Gastrectomy / Q000379:methods; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000556:secondary*; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery; D013997:Time Factors