title: Dermal and Ophthalmic Findings in Pseudohypoaldosteronism.
abstract: Pseudohypoaldosteronism (PHA) is defined as a state of resistance to aldosterone, a hormone crucial for electrolyte equilibrium. The genetically transmitted type of PHA is primary hypoaldosteronism. Secondary hypoaldosteronism develops as a result of hydronephrosis or hydroureter. PHA patients suffer from severe hyponatremia and a severe clinical condition due to severe loss of salt can be encountered in the neonatal period. Dermal findings in the form of miliaria rubra can also develop in these patients. With the loss of salt, abnormal accumulation of sebum in the eye due to a defect in the sodium channels can also occur. In this paper, a case of PHA in a newborn showing typical dermatological and ophthalmological findings is presented.
authors: Erciyes University Faculty of Medicine, Department of Neonatology, Kayseri, Turkey Phone:+90 352 207 66 66 E-mail: sabriyeyaman@hotmail.com.
authors: Sabriye
authors: S
authors: Korkut
authors: Emir
authors: E
authors: Gökalp
authors: Ahmet
authors: A
authors: Özdemir
authors: Selim
authors: S
authors: Kurtoğlu
authors: Şafak
authors: Ş
authors: Demirtaş
authors: Ülkü
authors: Ü
authors: Gül
authors: Osman
authors: O
authors: Baştuğ
mesh_terms: D005123:Eye / Q000473:pathology*; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology; D007231:Infant, Newborn; D011141:Polyuria / Q000209:etiology; D011546:Pseudohypoaldosteronism / Q000150:complications / Q000473:pathology*; D012629:Sebum / Q000737:chemistry; D012867:Skin / Q000473:pathology*; D015222:Sodium Channels / Q000378:metabolism
chemical_list: D015222:Sodium Channels