title: Genetics and gastric cancer susceptibility.
abstract: Gastric cancer has high morbidity and mortality in China. It is ranked first in malignant tumors of the digestive system. Its etiology and pathogenesis are still unclear, but they may be associated with a variety of factors. Genetic susceptibility genes have become a research hotspot in China. Elucidating the genetic mechanisms of gastric cancer can facilitate achieving individualized prevention and developing more effective methods to reduce clinical adverse consequences, which has important clinical significance. Genetic susceptibility results from the influence of genetic factors or specific genetic defects that endow an individual's offspring with certain physiological and metabolic features that are prone to certain diseases. Currently, studies on the genetic susceptibility genes of gastric cancer have become a hotspot. The purpose is to screen for the etiology of gastric cancer, search for gene therapy methods, and ultimately provide a scientific basis for the prevention and control of gastric cancer. This article reviews the current progress of studies on genetic susceptibility genes for gastric cancer.
authors: Department of Gastroenterology, Liaocheng People's Hospital Liaocheng 252000, China.
authors: Yan
authors: Y
authors: Lu
authors: Department of Traditional Chinese Medicine, Liaocheng People's Hospital Liaocheng 252000, China.
authors: Fang
authors: F
authors: Lu
authors: Central Laboratory, Liaocheng People's Hospital Liaocheng 252000, China.
authors: Sha
authors: S
authors: Zeng
authors: Foreign Affairs Office, Liaocheng People's Hospital Liaocheng 252000, China.
authors: Suqing
authors: S
authors: Sun
authors: Department of Pharmacy, Liaocheng International Peace Hospital Liaocheng 252000, China.
authors: Li
authors: L
authors: Lu
authors: Department of Gastroenterology, Liaocheng People's Hospital Liaocheng 252000, China.
authors: Lifeng
authors: L
authors: Liu
keywords: Gastric cancer; genetics; susceptibility