title: Dosimetry Support of the Ukrainian-American Case-control Study of Leukemia and Related Disorders Among Chornobyl Cleanup Workers.
abstract: This paper describes dose reconstruction for a joint Ukrainian-American case-control study of leukemia that was conducted in a cohort of 110,645 male Ukrainian cleanup workers of the Chornobyl (Chernobyl) accident who were exposed to various radiation doses over the 1986-1990 time period. Individual bone-marrow doses due to external irradiation along with respective uncertainty distributions were calculated for 1,000 study subjects using the RADRUE method, which employed personal cleanup history data collected in the course of an interview with the subject himself if he was alive or with two proxies if he was deceased. The central estimates of the bone-marrow dose distributions range from 3.7 × 10(-5) to 3,260 mGy, with an arithmetic mean of 92 mGy. The uncertainties in the individual stochastic dose estimates can be approximated by lognormal distributions; the average geometric standard deviation is 2.0.
authors: *National Research Centre for Radiation Medicine, Kyiv, Ukraine; †Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD; ‡Burnasyan Federal Medical Biophysical Centre, Moscow, Russia; §Department of Epidemiology and Biostatistics, University of California, San Francisco, CA; **Retired; ††MJP Risk Assessment, Inc., Denver, CO.
authors: Vadim
authors: V
authors: Chumak
authors: Vladimir
authors: V
authors: Drozdovitch
authors: Victor
authors: V
authors: Kryuchkov
authors: Elena
authors: E
authors: Bakhanova
authors: Natalya
authors: N
authors: Babkina
authors: Dimitry
authors: D
authors: Bazyka
authors: Natalya
authors: N
authors: Gudzenko
authors: Maureen
authors: M
authors: Hatch
authors: Natalya
authors: N
authors: Trotsuk
authors: Lydia
authors: L
authors: Zablotska
authors: Ivan
authors: I
authors: Golovanov
authors: Nickolas
authors: N
authors: Luckyanov
authors: Paul
authors: P
authors: Voillequé
authors: André
authors: A
authors: Bouville
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001822:Body Burden; D016022:Case-Control Studies; D047852:Chernobyl Nuclear Accident; D052918:Environmental Restoration and Remediation / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007953:Leukemia, Radiation-Induced / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000706:statistics & numerical data*; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000706:statistics & numerical data*; D018788:Radioactive Hazard Release / Q000706:statistics & numerical data*; D018570:Risk Assessment; D014455:Ukraine / Q000453:epidemiology; D014481:United States