title: Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database.
abstract: Many mouse models have been created to study hematopoietic cancer types. There are over thirty hematopoietic tumor types and subtypes, both human and mouse, with various origins, characteristics and clinical prognoses. Determining the specific type of hematopoietic lesion produced in a mouse model and identifying mouse models that correspond to the human subtypes of these lesions has been a continuing challenge for the scientific community. The Mouse Tumor Biology Database (MTB; http://tumor.informatics.jax.org) is designed to facilitate use of mouse models of human cancer by providing detailed histopathologic and molecular information on lymphoma subtypes, including expertly annotated, on line, whole slide scans, and providing a repository for storing information on and querying these data for specific lymphoma models.
authors: The Jackson Laboratory, Bar Harbor, ME USA. Electronic address: dale.begley@jax.org.
authors: Dale A
authors: DA
authors: Begley
authors: The Jackson Laboratory, Bar Harbor, ME USA.
authors: John P
authors: JP
authors: Sundberg
authors: The Jackson Laboratory, Bar Harbor, ME USA.
authors: Debra M
authors: DM
authors: Krupke
authors: The Jackson Laboratory, Bar Harbor, ME USA.
authors: Steven B
authors: SB
authors: Neuhauser
authors: The Jackson Laboratory, Bar Harbor, ME USA.
authors: Carol J
authors: CJ
authors: Bult
authors: The Jackson Laboratory, Bar Harbor, ME USA.
authors: Janan T
authors: JT
authors: Eppig
authors: Virology and Cellular Immunology Section, Laboratory of Immunogenetics, NIAID, NIH, Bethesda, MD USA.
authors: Herbert C
authors: HC
authors: Morse
authors: Global VetPathology, Montgomery Village, MD USA.
authors: Jerrold M
authors: JM
authors: Ward
mesh_terms: D000818:Animals; D016208:Databases, Factual; D004195:Disease Models, Animal; D006801:Humans; D007938:Leukemia / Q000473:pathology*; D008223:Lymphoma / Q000473:pathology*; D051379:Mice; D009374:Neoplasms, Experimental / Q000473:pathology*
keywords: Digital slides; Leukemia; Lymphoma; Mice; Mouse tumor biology database; Virtual slides