title: Di-tert-butyl peroxide-mediated atom-transfer radical addition of 2-chlorodithiane to aryl alkynes under mild conditions.
abstract: Atom transfer radical addition (ATRA) of 2-chlorodithiane onto aryl alkynes through the use of di-tert-butyl peroxide as an oxidant at room temperature directly affords a variety of synthetically valuable β-chloro-(Z)-vinyl dithianes in good yields with high regioselectivities and without the assistance of any transition metals. It provides an operationally simple pathway to access vinyl dithianes with controlled formation of a new C(sp(2) )C bond and a C(sp(2) )Cl bond.
authors: School of Pharmacy, Lanzhou University, Lanzhou 730000 (P. R. China).
authors: Junshan
authors: J
authors: Lai
authors: School of Pharmacy, Lanzhou University, Lanzhou 730000 (P. R. China).
authors: Lixia
authors: L
authors: Tian
authors: School of Pharmacy, Lanzhou University, Lanzhou 730000 (P. R. China).
authors: Yongping
authors: Y
authors: Liang
authors: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 (P. R. China).
authors: Yuan
authors: Y
authors: Zhang
authors: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 (P. R. China).
authors: Xingang
authors: X
authors: Xie
authors: Chemical Engineering Institute, Northwest University for Nationalities, Lanzhou, 730030 (P. R. China).
authors: Bowen
authors: B
authors: Fang
authors: School of Pharmacy, Lanzhou University, Lanzhou 730000 (P. R. China). tangshch@lzu.edu.cn.|State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 (P. R. China). tangshch@lzu.edu.cn.
authors: Shouchu
authors: S
authors: Tang
keywords: alkynes; atom transfer; radical addition; regioselectivity; sulfur heterocycles