title: Acantholytic dermatosis of the vulva.
abstract: Acantholytic dermatosis of the vulva is a rare condition, presenting with papular eruption in the genital area without history of Darier disease or Hailey-Hailey disease. We report a case with a papular pruritic eruption in the region of the vulva, coalescing into plaques. Biopsy specimen showed irregular acanthosis with an area of split-like bullous formation in the deeper part of the epidermis, as well as acantholytic cells, marked hypergranulosis and hyperkeratosis, compatible with the rare diagnosis of acantholytic dermatosis of the vulva. We review the clinical and histological characteristics of this uncommon disease.
authors: Adva
authors: A
authors: Mansura
authors: Alexander
authors: A
authors: Maly
authors: Yuval
authors: Y
authors: Ramot
authors: Hebrew University Medical Center, Jerusalem, Israel. zloto@cc.huji.ac.il.
authors: Abraham
authors: A
authors: Zlotogorski
mesh_terms: D000051:Acantholysis / Q000175:diagnosis*; D000328:Adult; D003937:Diagnosis, Differential; D004817:Epidermis / Q000473:pathology*; D005260:Female; D006801:Humans; D014844:Vulva / Q000473:pathology*; D014845:Vulvar Diseases / Q000175:diagnosis*