title: Clinical response in Mexican patients with irritable bowel syndrome treated with a low diet low in fermentable carbohydrates (FODMAP).
abstract: BACKGROUND
  The low FODMAP diet eliminates carbohydrates and fermentable alcohols because they are not absorbed by the intestine, but are fermented by the microbiota, causing bloating and flatulence.
  
  
  OBJECTIVE
  To evaluate the clinical response to the low FODMAP diet in patients with the different clinical subtypes of irritable bowel syndrome (IBS).
  
  
  METHODS
  Patients attended to at the Gastroenterology Department in 2014 that were diagnosed with IBS based on the Rome III criteria were included in the study. They were managed with a low FODMAP diet for 21 days and their response to the symptoms of abdominal pain, bloating, flatulence, and stool form pre and post-diet were evaluated through the visual analogue scale, Bristol scale, and patient overall satisfaction. The results were analyzed by means, 95% CI, and the Student's t test.
  
  
  RESULTS
  Of the 31 patients included in the study, 87% were women and the mean age was 46.48 years. Distribution was: IBS-C 64.5%, IBS-D 22.6%, and IBS-M 12.9%. The score for pain was 6.0 (95% CI 5.04-6.96) and the post-diet score was 2.77 (95% CI 1.60-3.95) (P<.001). The score for bloating was 7.10 (95% CI 6.13-8.06) and the post-diet score was 4.19 (95% CI 2.95-5.44) (P<.001). The score for flatulence was 5.94 (95% CI 4.79-7.08) and the post-diet score was 3.06 (IC95% 1.99-4.14) (P<.001). The pre-diet Bristol Scale result was 3.68 (95% CI 3.14-4.22) and the post-diet result was 4.10 (95% CI 3.66-4.54) (P=.1). The satisfaction percentage was 70.9%.
  
  
  CONCLUSIONS
  In this first study on a Mexican population with IBS, there was significant improvement of the main symptoms, including pain, bloating, and flatulence after treatment with a low FODMAP diet.
authors: Laboratorio de Motilidad Gastrointestinal y Clínica de ERGE y trastornos funcionales digestivos, SSA, México D.F., México. Electronic address: sonelle74@hotmail.com.
authors: N
authors: N
authors: Pérez y López
authors: Servicio de Cirugía General, Hospital Ángeles Lindavista, México D.F., México.
authors: E
authors: E
authors: Torres-López
authors: Servicio de Gastroenterología, Hospital Juárez de México, SSA, México D.F., México.
authors: F
authors: F
authors: Zamarripa-Dorsey
mesh_terms: D000328:Adult; D000368:Aged; D002446:Celiac Disease / Q000178:diet therapy; D055050:Diet, Gluten-Free; D004040:Dietary Carbohydrates / Q000009:adverse effects; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000150:complications / Q000175:diagnosis / Q000178:diet therapy*; D008137:Longitudinal Studies; D008297:Male; D008800:Mexico; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D017060:Patient Satisfaction; D011446:Prospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D004040:Dietary Carbohydrates
keywords: Abdominal pain; Diet; Diet low in fermentable carbohydrates; Dieta; Dieta baja en carbohidratos fermentables; Dolor abdominal; Flatulence; Flatulencia; Irritable bowel syndrome; Síndrome de intestino irritable