title: 3-Aza π-allyl palladium derived from imino migration in palladium-carbene: MCRs toward multiple substituted indole skeleton.
abstract: Palladium-catalyzed multi-component reactions (MCRs) between 2-iodoaniline, aryl isonitrile, N-tosylhydrazones and solvent were developed. This procedure features the migration of the imino group in palladium-carbene to produce a 3-aza π-allyl palladium species. Then, intramolecular nucleophilic attack of the π-allyl palladium species by the amino group takes place facilely, thus producing a 1,2,3-trisubstitued indole skeleton, which has high diversity and complexity.
authors: School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Jiangsu Province Key Laboratory of Fine Petrochemical Engineering, Changzhou University, Changzhou, 213164, P. R. China. jiangcheng@cczu.edu.cn.
authors: Qiang
authors: Q
authors: Dai
authors: Yan
authors: Y
authors: Jiang
authors: Songjin
authors: S
authors: Guo
authors: Jin-Tao
authors: JT
authors: Yu
authors: Jiang
authors: J
authors: Cheng