title: [Drug management of prisoners: Role of the pharmaceutical staff to ensure patient safety].
abstract: OBJECTIVE
  In the prisons of Lyon, drug management of inmates implies cooperation between general practitioners, psychiatrists and pharmacists. All the medical prescriptions are reviewed by the pharmacists of the medical unit. The aim of this work was to synthesize the pharmaceutical interventions performed and show the implication of the pharmaceutical staff in detecting and handling prescribing errors.
  
  
  METHODS
  Pharmaceutical interventions performed between the 1st of June 2012 and the 31st December 2014 and entered in the Act-IP(®) database (SFPC) were retrospectively analyzed.
  
  
  RESULTS
  Among the 18,205 prescriptions reviewed, 4064 (22.3%) had a prescription error. The main problems encountered were by decreasing order of frequency: missing monitoring (15% of the interventions), lack of compliance (13%), over dosage (10%), lack of conformity with recommendations or consensus (8%). Interventions were accepted in 78% cases. Most prescribing errors implied medications of the central nervous system. Among the interventions, 8% were initiated by pharmacy technicians, mainly lack of compliance.
  
  
  CONCLUSIONS
  The pharmaceutical interventions reported reflected actions of securisation initiated by the pharmacists in cooperation with physicians: monitoring of patients taking antipsychotic medications or benzodiazepines maximal dosages. Besides, in this population with a high prevalence of psychiatric comorbidities and important suicide rate, detection of patients with default of compliance is one of the keys for drug optimization among these patients as it is an explanation for therapeutic failure.
authors: Unité de pharmacie clinique en milieu carcéral, maison d'arrêt de Lyon-Corbas, groupement hospitalier Sud, hospices civils de Lyon, boulevard des Nations, 69960 Corbas, France. Electronic address: laure.lalande@chu-lyon.fr.
authors: L
authors: L
authors: Lalande
authors: Unité de pharmacie clinique en milieu carcéral, maison d'arrêt de Lyon-Corbas, groupement hospitalier Sud, hospices civils de Lyon, boulevard des Nations, 69960 Corbas, France.
authors: C
authors: C
authors: Bertin
authors: Service de pharmacie, groupement hospitalier Sud, hospices civils de Lyon, bâtiment 3A, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France.
authors: C
authors: C
authors: Rioufol
authors: Service de pharmacie, groupement hospitalier Sud, hospices civils de Lyon, bâtiment 3A, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France.
authors: P
authors: P
authors: Boleor
authors: Unité de pharmacie clinique en milieu carcéral, maison d'arrêt de Lyon-Corbas, groupement hospitalier Sud, hospices civils de Lyon, boulevard des Nations, 69960 Corbas, France.
authors: D
authors: D
authors: Cabelguenne
mesh_terms: D000328:Adult; D000368:Aged; D011307:Drug Prescriptions / Q000592:standards; D005260:Female; D006801:Humans; D008297:Male; D054539:Medication Therapy Management; D008875:Middle Aged; D061214:Patient Safety; D010594:Pharmacies / Q000458:organization & administration; D010595:Pharmacists; D011329:Prisoners; D011330:Prisons; D012189:Retrospective Studies
keywords: Clinical pharmacy; Intervention pharmaceutique; Medical prescription; Pharmaceutical intervention; Pharmacie clinique; Prescription médicamenteuse; Prison; Prisoners; Psychotropes; Psychotropic medications