title: Use of tumor necrosis factor alpha (TNF α) antagonists in a patient with psoriasis and Chagas disease.
abstract: There are several studies on the benefits of using TNFα antagonists in the treatment of psoriasis, but few studies addressing the interaction of these drugs with chronic infections. We report the case of a 52-year-old patient diagnosed with psoriasis refractory to traditional systemic agents, who was treated with biologic therapies. After one year of treatment with biologic agents, the patient was diagnosed with Chagas Disease.
authors: Pontificia Universidad Católica de Chile, Santiago, CL.
authors: Cristián
authors: C
authors: Navarrete-Dechent
authors: Pontificia Universidad Católica de Chile, Santiago, CL.
authors: Daniela
authors: D
authors: Majerson
authors: Pontificia Universidad Católica de Chile, Santiago, CL.
authors: Marisa
authors: M
authors: Torres
authors: Pontificia Universidad Católica de Chile, Santiago, CL.
authors: Daniela
authors: D
authors: Armijo
authors: University Medical Center, Dallas, TX, US.
authors: Mahir
authors: M
authors: Patel
authors: University Medical Center, Dallas, TX, US.
authors: Alan
authors: A
authors: Menter
authors: Pontificia Universidad Católica de Chile, Santiago, CL.
authors: Claudia
authors: C
authors: de la Cruz
mesh_terms: D000068879:Adalimumab / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001685:Biological Factors / Q000627:therapeutic use; D001691:Biological Therapy / Q000379:methods; D014355:Chagas Disease / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011565:Psoriasis / Q000188:drug therapy*; D015203:Reproducibility of Results; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D000893:Anti-Inflammatory Agents; D001685:Biological Factors; D014409:Tumor Necrosis Factor-alpha; D000068879:Adalimumab