title: Exploiting In Situ Solid-State NMR for the Discovery of New Polymorphs during Crystallization Processes.
abstract: We report the discovery of new polymorphic forms of solids by exploiting a solid-state NMR technique that has been developed for in situ monitoring of the evolution of crystallization processes. The capability of the technique to reveal the existence of new polymorphic forms of molecular solids is illustrated by the discovery of two new polymorphs of methyldiphenylphosphine oxide and a new solid form of the 1,10-dihydroxydecane/urea system.
authors: School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, Wales, U.K.
authors: Colan E
authors: CE
authors: Hughes
authors: School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, Wales, U.K.
authors: P Andrew
authors: PA
authors: Williams
authors: School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, Wales, U.K.
authors: Thomas R
authors: TR
authors: Peskett
authors: School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, Wales, U.K.
authors: Kenneth D M
authors: KD
authors: Harris
keywords: crystallization; in situ techniques; polymorphism; solid-state NMR