title: Bilateral Cystoid Macular Edema Secondary to Paclitaxel Treatment.
abstract: Cystoid macular edema is rarely observed secondary to paclitaxel treatment. A 55-year-old female patient was applied five cures of paclitaxel and carboplatin chemotherapy after being diagnosed with metastatic ovarian cancer. The patient had a normal bilateral vision prior to the chemotherapy treatments. After the fifth cure, the patient complained of bilateral vision loss, which was more severe in the left eye. Ophthalmologic examination revealed that right eye vision was 4/10 blurred without glasses and 7/10 blurred with glasses, left eye vision was 1/10 blurred without glasses and 4/10 blurred with glasses. Pathology was not detected during the biomicroscopic examination. Fundus examination of the patient revealed pigment epithelium irregularity, which was found to be less in the right eye, and it was found a decrease in foveal cavity. For fundus examination, the patient underwent fundus fluorescein angiography (FFA) and optical coherence tomography (OCT). FFA revealed fluorescein leakage and cystoid appearance particularly more apparent in the left eye. Thickening in the macula and cystoid space was observed particularly more in the left eye in the OCT measurement. In conclusion, we presented our case as a rarely observed cystoid macular edema secondary to paclitaxel treatment.
authors: N. E. U., Department of Radiation Oncology, Meram Faculty of Medicine, Konya, Turkey. yilmaztezcan@yahoo.com.
authors: Yilmaz
authors: Y
authors: Tezcan
authors: N. E. U., Department of Radiation Oncology, Meram Faculty of Medicine, Konya, Turkey.
authors: Mustafa
authors: M
authors: Surmeli
authors: I. U., Department of Medical Oncology, Istanbul Faculty of Medicine, Istanbul, Turkey.
authors: Didem
authors: D
authors: Tastekin
authors: N. E. U., Department of Radiation Oncology, Meram Faculty of Medicine, Konya, Turkey.
authors: Mehmet
authors: M
authors: Koc
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008269:Macular Edema / Q000139:chemically induced* / Q000175:diagnosis; D008875:Middle Aged; D017239:Paclitaxel / Q000009:adverse effects*; D041623:Tomography, Optical Coherence
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel