title: Dissemination of carbapenemase-producing Enterobacteriaceae and Pseudomonas aeruginosa in Romania.
abstract: Fifteen carbapenemase-producing Enterobacteriaceae isolates and 12 carbapenemase-producing Pseudomonas aeruginosa isolates were recovered from patients hospitalized between August 2011 and March 2013 at the Hospital of Infectious Disease, Cluj-Napoca, Romania. One KPC-, nine NDM-1-, four OXA-48-, and one VIM-4-producing Enterobacteriaceae isolates along with 11 VIM-2-producing and one IMP-13-producing P. aeruginosa isolates were recovered from clinical samples. All carbapenemase genes were located on self-conjugative plasmids and were associated with other resistance determinants, including extended-spectrum β-lactamases and RmtC methylases.
authors: Bacteriology-Hygiene Unit, Assistance Publique/Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France Paris-Sud University, LabEx Lermit, Faculty of Medecine, Le Kremlin-Bicêtre, France Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bicêtre, France Laurent.dortet@aphp.fr.
authors: Laurent
authors: L
authors: Dortet
authors: Clinical Hospital of Infectious Diseases, Microbiology Laboratory, Cluj-Napoca, Romania.
authors: Mirela
authors: M
authors: Flonta
authors: Paris-Sud University, LabEx Lermit, Faculty of Medecine, Le Kremlin-Bicêtre, France.
authors: Yves-Marie
authors: YM
authors: Boudehen
authors: Paris-Sud University, LabEx Lermit, Faculty of Medecine, Le Kremlin-Bicêtre, France.
authors: Elodie
authors: E
authors: Creton
authors: Bacteriology-Hygiene Unit, Assistance Publique/Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France Paris-Sud University, LabEx Lermit, Faculty of Medecine, Le Kremlin-Bicêtre, France Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bicêtre, France.
authors: Sandrine
authors: S
authors: Bernabeu
authors: Paris-Sud University, LabEx Lermit, Faculty of Medecine, Le Kremlin-Bicêtre, France.
authors: Anaïs
authors: A
authors: Vogel
authors: Bacteriology-Hygiene Unit, Assistance Publique/Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France Paris-Sud University, LabEx Lermit, Faculty of Medecine, Le Kremlin-Bicêtre, France Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bicêtre, France.
authors: Thierry
authors: T
authors: Naas
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000378:metabolism*; D004755:Enterobacteriaceae / Q000187:drug effects / Q000201:enzymology*; D010957:Plasmids / Q000235:genetics; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000201:enzymology*; D012383:Romania; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase