title: Comparison of situs ambiguous patterns between heterotaxy syndromes with polysplenia and asplenia.
abstract: OBJECTIVE
  To compare the differences of visceral anomalies shown by computed tomography (CT) in patients with polysplenia syndrome (PS) or asplenia syndrome (AS).
  
  
  METHODS
  This retrospective study was approved by the institutional review board, and informed consent was waived. Thirty-one patients with PS and 29 patients with AS underwent chest-abdominal CT. The evaluated CT findings were as follows: the orientation of stomach, liver and gallbladder; short pancreas; azygous/hemiazygous continuation; ipsilateral position of the inferior vena cava and aorta; preduodenal portal vein; abnormal confluence of renal vein (defined as renal vein drains to the inferior vena cava or azygous/hemiazygous vein at the upper level of celiac trunk origin); gastrointestinal malrotation; and tracheobronchial tree.
  
  
  RESULTS
  Azygous/hemiazygous continuation was seen in 74% (20 of 27)/0% (0 of 28) of PS/AS (P<0.0001), bilateral hyparterial bronchi in 75% (24 of 32)/5% (1 of 22), bilateral eparterial bronchi in 9% (3 of 32)/95% (21 of 22), ipsilateral position of the inferior vena cava and aorta in 59% (16 of 27)/89% (25 of 28), and abnormal confluence of renal vein in 7% (2 of 27)/57% (16 of 28), respectively. No significant differences were found in the other anomalies.
  
  
  CONCLUSIONS
  Significant differences in anomalous systemic venous connections and tracheobronchial anomaly were observed between PS and AS. Abnormal confluence of renal vein is relatively rare anomalous venous connections, but frequently observed in AS.
authors: Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.
authors: Hiroko
authors: H
authors: Yoneyama
authors: Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. Electronic address: pkondou@pop02.odn.ne.jp.
authors: Chisato
authors: C
authors: Kondo
authors: Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.
authors: Aki
authors: A
authors: Yamasaki
authors: Department of Pediatric Cardiology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.
authors: Toshio
authors: T
authors: Nakanishi
authors: Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.
authors: Shuji
authors: S
authors: Sakai
mesh_terms: D000293:Adolescent; D000328:Adult; D001401:Azygos Vein / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D005260:Female; D059446:Heterotaxy Syndrome / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D008099:Liver / Q000000981:diagnostic imaging; D008297:Male; D010179:Pancreas / Q000000981:diagnostic imaging; D011169:Portal Vein / Q000000981:diagnostic imaging; D012082:Renal Veins / Q000002:abnormalities / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D013154:Spleen / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D013270:Stomach / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging; D055815:Young Adult
keywords: Asplenia; Heterotaxy syndrome; Multidetector Computed Tomography; Polysplenia; Renal vein; Situs ambiguus viscerum