title: Synthesis of Adjacent Quaternary Stereocenters by Catalytic Asymmetric Allylboration.
abstract: Allylboration of ketones with γ-disubstituted allylboronic acids is performed in the presence of chiral BINOL derivatives. The reaction is suitable for single-step creation of adjacent quaternary stereocenters with high selectivity. We show that, with an appropriate choice of the chiral catalyst and the stereoisomeric prenyl substrate, full control of the stereo- and enantioselectivity is possible in the reaction.
authors: Department of Organic Chemistry and ‡Department of Materials and Environmental Chemistry, Stockholm University , SE-106 91 Stockholm, Sweden.
authors: Rauful
authors: R
authors: Alam
authors: Department of Organic Chemistry and ‡Department of Materials and Environmental Chemistry, Stockholm University , SE-106 91 Stockholm, Sweden.
authors: Tobias
authors: T
authors: Vollgraff
authors: Department of Organic Chemistry and ‡Department of Materials and Environmental Chemistry, Stockholm University , SE-106 91 Stockholm, Sweden.
authors: Lars
authors: L
authors: Eriksson
authors: Department of Organic Chemistry and ‡Department of Materials and Environmental Chemistry, Stockholm University , SE-106 91 Stockholm, Sweden.
authors: Kálmán J
authors: KJ
authors: Szabó