title: Weak Coordination Promoted Regioselective Oxidative Coupling Reaction for 2,2'-Difunctional Biaryl Synthesis in Hexafluoro-2-propanol.
abstract: An unprecedented weak coordination promoted dehydrogenative cross-coupling reaction has been developed by palladium catalysis, which provides a convenient access to a wide range of 2,2'-difunctional biaryls from easily accessible substrates. Both HFIP solvent and oxidants serve as the critical factors in this new reaction. A plausible mechanism involving Pd(II)/Pd(IV) is proposed. The reaction demonstrates excellent reactivity, broad functional-group tolerance and high yields.
authors: MOE Key Laboratory of Protein Sciences, Department of Pharmacology and Pharmaceutical Sciences, School of Medicine and School of Life Sciences, Tsinghua University , Beijing 100084, China.
authors: Chao
authors: C
authors: Zhang
authors: MOE Key Laboratory of Protein Sciences, Department of Pharmacology and Pharmaceutical Sciences, School of Medicine and School of Life Sciences, Tsinghua University , Beijing 100084, China.
authors: Yu
authors: Y
authors: Rao