title: Tamoxifen-associated portal vein thrombosis causing severe oesophageal variceal bleeding.
abstract: A 46-year-old woman with medical history of breast cancer on tamoxifen presented with syncope. On arrival to the hospital, the patient developed massive haematemesis and a subsequent esophagogastroduodenoscopy revealed oesophageal varices without any known history of liver disease. Further evaluation identified portal vein thrombosis probably caused by tamoxifen use.
authors: Department of Medicine, University of Massachusetts, Worcester, Massachusetts, USA.
authors: Andrew
authors: A
authors: Hsu
authors: Department of Gastroenterology, University of Massachusetts, Worcester, Massachusetts, USA.
authors: Edward
authors: E
authors: Belkin
authors: Department of Medicine, University of Massachusetts, Worcester, Massachusetts, USA.
authors: Samuel
authors: S
authors: Han
authors: Department of Gastroenterology, University of Massachusetts, Worcester, Massachusetts, USA.
authors: Randall
authors: R
authors: Pellish
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D001803:Blood Transfusion; D001943:Breast Neoplasms / Q000188:drug therapy / Q000517:prevention & control*; D017024:Chemotherapy, Adjuvant / Q000009:adverse effects*; D016145:Endoscopy, Digestive System; D004932:Esophageal and Gastric Varices / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D011169:Portal Vein; D013575:Syncope / Q000209:etiology; D013629:Tamoxifen / Q000009:adverse effects*; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000139:chemically induced* / Q000150:complications / Q000473:pathology
chemical_list: D018931:Antineoplastic Agents, Hormonal; D013629:Tamoxifen