title: Selective amination of aryl chlorides catalysed by Ni(PMe3)4.
abstract: C,N-coupling reactions of aryl chlorides and aryl amines catalyzed by a nickel catalyst are reported. 17 new amines are synthesized in yields of 57-99%. 2,6-Dichloro substituted imines can be selectively aminated. Both mono- and di-aminated products are obtained. Different substrates and amines are tested to look into the influence of electronic effects and steric hindrance to the reaction. An inexpensive and convenient base, NaOH, is used. It is an efficient way to gain access to new amines and imines.
authors: School of Chemistry and Chemical Engineering, Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, Shandong University, Shanda Nanlu 27, 250199 Jinan, PR China. hjsun@sdu.edu.cn.
authors: Shumiao
authors: S
authors: Zhang
authors: Xiaoyan
authors: X
authors: Li
authors: Hongjian
authors: H
authors: Sun