title: Robot-assisted partial nephrectomy in cystic tumours: analysis of the Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database.
abstract: OBJECTIVE
  To evaluate the outcomes of robot-assisted partial nephrectomy (RAPN) in cystic tumours, analysing a large, multi-institutional, retrospective series of RAPN, as limited data are available about the outcome of RAPN in cystic tumours.
  
  
  METHODS
  We evaluated 465 patients who received RAPN for either cystic or solid tumours from 2010 to 2013 and included in the multi-institutional, retrospective Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database. Univariable and multivariable linear and logistic regression models addressed the association of cystic tumours with perioperative outcomes.
  
  
  RESULTS
  In all, 54 (12%) tumours were cystic. Cystic tumours were associated with significantly lower operative time (t -3.9; P < 0.001), once adjusted for the effect of covariates, whereas blood loss and warm ischaemia time were similar. Postoperative any grade complications were recorded in 66 solid (16%) and nine cystic (17%) tumours (P = 0.08). In multivariable analysis, cystic tumours were not associated with a significantly lower risk of any grade postoperative complications [odds ratio (OR) 0.9; P = 0.8]. Similarly, presence of tumours with cystic features was not associated with a significantly different risk of high-grade postoperative complications (OR 2.2; P = 0.1). Prevalence of cancer histology and positive surgical margin rates were similar in cystic and solid tumours. Cystic tumours were not associated with significantly different postoperative estimated glomerular filtration rate (t 0.4; P = 0.7), once adjusted for the effect of covariates.
  
  
  CONCLUSIONS
  RAPN can be performed in cystic renal tumours with perioperative, pathological, and functional outcomes similar to those achievable in solid tumours.
authors: Department of Surgery, Oncology, and Gastroenterology - Urology Clinic, University of Padua, Padua, Italy.
authors: Giacomo
authors: G
authors: Novara
authors: Department of Surgery, Oncology, and Gastroenterology - Urology Clinic, University of Padua, Padua, Italy.
authors: Sabrina
authors: S
authors: La Falce
authors: Department of Urology, Ohio Health Dublin Methodist Hospital, Dublin, OH, USA.
authors: Ronney
authors: R
authors: Abaza
authors: Hertfordshire and South Bedfordshire Urological Cancer Centre, Lister Hospital, Stevenage, UK.
authors: James
authors: J
authors: Adshead
authors: Division of Urology and Renal Transplantation, Medanta Kidney and Urology Institute, Medanta, the Medicity, Gurgaon, India.
authors: Rajesh
authors: R
authors: Ahlawat
authors: Humanitas Clinical and Research Center, Rozzano, Milan, Italy.
authors: Nicolò Maria
authors: NM
authors: Buffi
authors: MRC Centre for Transplantation, King's College London, London, UK.
authors: Ben
authors: B
authors: Challacombe
authors: MRC Centre for Transplantation, King's College London, London, UK.
authors: Prokar
authors: P
authors: Dasgupta
authors: Peter MacCallum Cancer Centre, Melbourne, Vic., Australia.
authors: Daniel A
authors: DA
authors: Moon
authors: University of Miami Miller School of Medicine and Sylvestor Comprehensive Cancer Center, Miami, FL, USA.
authors: Dipen J
authors: DJ
authors: Parekh
authors: San Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy.
authors: Francesco
authors: F
authors: Porpiglia
authors: Rajiv Gandhi Cancer Hospital, New Delhi, India.
authors: Sudhir
authors: S
authors: Rawal
authors: Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA.
authors: Craig
authors: C
authors: Rogers
authors: University of Eastern Piedmont, Novara, Italy.
authors: Alessandro
authors: A
authors: Volpe
authors: Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI, USA.
authors: Mahendra
authors: M
authors: Bhandari
authors: Department of Urology, Onze-Lieve-Vrouw Hospital, Aalst, Belgium.|OLV Vattikuti Robotic Surgery Institute, Aalst, Belgium.
authors: Alexander
authors: A
authors: Mottrie
mesh_terms: D000368:Aged; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D007680:Kidney Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods* / Q000592:standards; D061646:Operative Time; D011787:Quality of Health Care; D012189:Retrospective Studies; D065287:Robotic Surgical Procedures / Q000379:methods* / Q000592:standards; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden
keywords: cystic tumour; kidney; partial nephrectomy; renal cell carcinoma (RCC)