title: The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (n = 93).
abstract: This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in J Autism Dev Disord 44(8):1996-2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off resembled the original algorithm ASD cut-off: highly specific for psychopathy and controls, lower sensitivity than Hus and Lord (2014; i.e. ASD .61, AD .53). The revised algorithm AD cut-off improved sensitivity over the original algorithm. Discriminating ASD from schizophrenia was still challenging, but the better-balanced sensitivity (.53) and specificity (.78) of the revised algorithm AD cut-off may aide clinicians' differential diagnosis. Findings support using the revised algorithm, being conceptually conform the other modules, thus improving comparability across the lifespan.
authors: Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. a.de.bildt@accare.nl.|Accare University Center for Child and Adolescent Psychiatry, PO Box 660, 9700 AR, Groningen, The Netherlands. a.de.bildt@accare.nl.
authors: Annelies
authors: A
authors: de Bildt
authors: Interdisciplinary Center for Psychopathology and Emotion Regulation (ICPE), Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
authors: Sjoerd
authors: S
authors: Sytema
authors: Section on Affective and Cognitive Neuroscience, National Institutes of Health, Bethesda, MD, USA.|Social Brain Lab, Department of Neuroscience, University Medical Center Groningen, Groningen, The Netherlands.|Forensic Psychiatric Clinic Dr. S. van Mesdag, Groningen, The Netherlands.
authors: Harma
authors: H
authors: Meffert
authors: Interdisciplinary Center for Psychopathology and Emotion Regulation (ICPE), Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.|Forensic Psychiatric Clinic Dr. S. van Mesdag, Groningen, The Netherlands.|Autism Team North Netherlands, Lentis, Groningen, The Netherlands.
authors: Jojanneke A C J
authors: JACJ
authors: Bastiaansen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D000067877:Autism Spectrum Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D012559:Schizophrenia / Q000175:diagnosis; D012919:Social Behavior; D055815:Young Adult
keywords: Adults; Assessment; Autism Spectrum Disorder; Classification; Psychopathy; Schizophrenia