title: Minimally invasive resection of olfactory neuroblastoma by transnasal endoscopy.
abstract: Olfactory neuroblastoma is rare. We conducted a retrospective study to review our experience with minimally invasive resection of olfactory neuroblastomas via a transnasal endoscopic technique, including an analysis of surgical outcomes. Our series included 5 patients-3 men and 2 women, aged 29 to 75 years (mean: 48). Surgical outcomes were evaluated on the basis of each patient's preoperative Dulguerov classification and postoperative evaluation on computed tomography and magnetic resonance imaging. One patient was treated with surgery alone, 3 with surgery plus radiotherapy, and 1 with surgery, radiotherapy, and chemotherapy. During follow-up of 18 to 115 months, all 5 patients remained alive and disease-free. We found that endoscopic resection of olfactory neuroblastoma is a feasible and effective procedure, even in patients with more aggressive stages of disease. We also believe that the Dulguerov classification is more useful than other classifications for clinical management and surgical planning. Long-term follow-up is necessary to look for late recurrence.
authors: Department of Otorhinolaryngology-Head and Neck Surgery, Changhua Christian Hospital, #135 Nanhsiau St., Changhua 500, Taiwan.
authors: Chin-Fang
authors: CF
authors: Chang
authors: Sheng-Chang
authors: SC
authors: Chiu
authors: Shiou-Yu
authors: SY
authors: Yeh
authors: Mu-Kuan
authors: MK
authors: Chen
authors: Yung-Sung
authors: YS
authors: Wen
mesh_terms: D000328:Adult; D000368:Aged; D004724:Endoscopy / Q000379:methods*; D018304:Esthesioneuroblastoma, Olfactory / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000000981:diagnostic imaging / Q000601:surgery*; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*