title: Review article: BK virus in systemic lupus erythematosus.
abstract: BK virus (BKV) is a human polyomavirus with a seroprevalence of 60-80 % in the general population. In renal transplant patients, it is known to cause renal failure, ureteric stenosis and hemorrhagic cystitis. In bone marrow transplant patients, it is evident that BKV can also cause hemorrhagic cystitis along with BK virus nephropathy (BKVN) in the native kidneys, with subsequent renal failure. However, little is known about BVKN in non-transplanted immune-compromised patients, such as systemic lupus erythematosus (SLE) who may have underlying nephritis and have a compromised immune system due to therapy and/or systemic illness. Thus, this article will focus on the clinical aspects of BKV and its association in patients with SLE.
authors: Division of Nephrology, Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. peacock7@ufl.edu.
authors: Nirupama
authors: N
authors: Gupta
authors: Division of Immunology, Rheumatology and Infectious Diseases, Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. lawrerm@peds.ufl.edu.
authors: Robert M
authors: RM
authors: Lawrence
authors: Department of Infectious Diseases and Pathology, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610, USA. nguyenc@ufl.edu.
authors: Cuong
authors: C
authors: Nguyen
authors: Division of Immunology, Rheumatology and Infectious Diseases, Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. modicar@peds.ufl.edu.
authors: Renee F
authors: RF
authors: Modica
mesh_terms: D001739:BK Virus; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000821:virology*; D027601:Polyomavirus Infections / Q000150:complications* / Q000453:epidemiology; D014412:Tumor Virus Infections / Q000150:complications* / Q000453:epidemiology