title: Eosinophilic ulcer of the tongue--Case report.
abstract: Eosinophilic ulcer of the oral mucosa is a rare, self-limiting, chronic and benign lesion of unknown pathogenesis that affects the oral mucosa. We present the case of a 65 year-old Caucasian female with a five month history of a painful ulcer on the lateral side of her tongue. The ulcer was not adhered to the underlying structures and there was no evidence of regional lymph node involvement. Laboratory examinations and X-rays revealed no abnormalities. Topical treatments had been performed without any improvement. Histopathological examination showed an ulcerated surface and mixed inflammatory infiltrate with several eosinophils extending into the mucosa and submucosa. No cellular atypia was observed. Based on the patient-s history and mucosal biopsy, a final diagnosis of eosinophilic ulcer of the oral mucosa was made.
authors: Hospitalization and Health Care, Istituto Dermopatico dell'Immacolata, Rome, IT.
authors: Dario
authors: D
authors: Didona
authors: Clinica Dermatologica, La Sapienza University of Rome, Rome, IT.
authors: Giovanni
authors: G
authors: Paolino
authors: Hospitalization and Health Care, Scientific Institute for Research, San Gallicano Institute, Rome, IT.
authors: Michele
authors: M
authors: Donati
authors: Hospitalization and Health Care, Istituto Dermopatico dell'Immacolata, Rome, IT.
authors: Biagio
authors: B
authors: Didona
authors: Clinica Dermatologica, La Sapienza University of Rome, Rome, IT.
authors: Stefano
authors: S
authors: Calvieri
mesh_terms: D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000473:pathology*; D005260:Female; D006801:Humans; D009061:Mouth Mucosa / Q000473:pathology; D019226:Oral Ulcer / Q000473:pathology*; D014060:Tongue Diseases / Q000473:pathology*