title: Adult patent ductus arteriosus complicated by endocarditis and hemolytic anemia.
abstract: An adult with a large patent ductus arteriosus may present with fatigue, dyspnea or palpitations or in rare presentation with endocarditis. The case illustrated unique role of vegetation of endocarditis in hemolytic anemia in adult with patent ductus arteriosus (PDA). Despite treatment of endocarditis with complete course of appropriate antibiotic therapy and normality of C- reactive protein, erythrocyte sedimentation rate and leukocytosis and wellness of general condition, transthoracic echocardiography revealed large vegetation in PDA lumen, surgical closure of PDA completely relieved hemolysis, and fragmented red cell disappeared from peripheral blood smear. The 3-month follow-up revealed complete occlusion of PDA and abolishment of hemolytic anemia confirmed by clinical and laboratory examination.
authors: Preventive Cardiovascular Research Centre Kermanshah, Kermanshah University of Medical Sciences, Kermanshah, Iran.
authors: Feridoun
authors: F
authors: Sabzi
authors: Preventive Cardiovascular Research Centre Kermanshah, Kermanshah University of Medical Sciences, Kermanshah, Iran.
authors: Reza
authors: R
authors: Faraji
mesh_terms: D000328:Adult; D000743:Anemia, Hemolytic / Q000209:etiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001799:Blood Sedimentation; D004374:Ductus Arteriosus, Patent / Q000150:complications / Q000601:surgery*; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents
keywords: Ductus Arteriosus; anemia; dyspnea; endocarditis, hemolytic; fatigue; leukocytosis