title: Surgical Treatment of Giant Liver Hemangioma Larger Than 10 cm: A Single Center's Experience With 86 Patients.
abstract: The ideal surgical treatment of giant liver hemangioma is still controversial. This study aims to compare the outcomes of enucleation with those of resection for liver hemangioma larger than 10 cm in different locations of the liver and establish the preoperative predictors of increased intraoperative blood loss.Eighty-six patients underwent enucleation or liver resection for liver hemangioma larger than 10 cm was retrospectively reviewed. Patient demographic, tumor characteristics, surgical indications, the outcomes of both surgical treatment, and the clinicopathological parameters influencing intraoperative blood loss were analyzed.Forty-six patients received enucleation and 40 patients received liver resection. Mean tumor size was 14.1 cm with a range of 10-35 cm. Blood loss, blood product usage, operative time, hepatic vascular occlusion time and frequency, complications and postsurgical hospital stay were similar between liver resections and enucleation for right-liver and left-liver hemangiomas. There was no surgery-related mortality in either group. Bleeding was more related to adjacency of major vascular structures than the size of hemangioma. Adjacency to major vascular structures and right or bilateral liver hemangiomas were independently associated with blood loss >550 mL (P = 0.000 and 0.042, respectively).Both enucleation and liver resection are safe and effective surgical treatments for liver hemangiomas larger than 10 cm. The risk of intraoperative blood loss is related to adjacency to major vascular structures and the location of hemangioma.
authors: From the Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China (WZ, Z-YH, CW, Z-WZ, B-XZ, Y-FC, W-GZ, PZ, X-PC); Department of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China (C-SK); and Key Laboratory of Organ Transplantation, Ministry of Education, China, and Key Laboratory of Organ Transplantation, Ministry of Public Health, People's Republic of China (X-PC).
authors: Wei
authors: W
authors: Zhang
authors: Zhi-Yong
authors: ZY
authors: Huang
authors: Chang-Shu
authors: CS
authors: Ke
authors: Chao
authors: C
authors: Wu
authors: Zhi-Wei
authors: ZW
authors: Zhang
authors: Bi-Xiang
authors: BX
authors: Zhang
authors: Yi-Fa
authors: YF
authors: Chen
authors: Wan-Guang
authors: WG
authors: Zhang
authors: Peng
authors: P
authors: Zhu
authors: Xiao-Ping
authors: XP
authors: Chen
mesh_terms: D000328:Adult; D000368:Aged; D016063:Blood Loss, Surgical; D005260:Female; D006391:Hemangioma / Q000473:pathology* / Q000601:surgery*; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D047368:Tumor Burden