title: Comparison of extraction solvents and sorbents in the quick, easy, cheap, effective, rugged, and safe method for the determination of pesticide multiresidue in fruits by ultra high performance liquid chromatography with tandem mass spectrometry.
abstract: An improved analytical method was developed for the simultaneous quantification of several plant growth regulators and fungicides (carbendazim, pyrimethanil, metalaxyl, triadimefon, paclobutrazol, thiophanate, prochloraz, dimethomorph, difenoconazole, (4-chlorophenoxy)-acetic acid, (2,4-dichlorophenoxy)-acetic acid, thiadiazuron, forchlorfenuron and gibberellins) in fruits followed by ultra high performance liquid chromatography with tandem mass spectrometry. Samples were extracted and purified using a modified QuEChERS method. Different extraction solvents and sorbents in the QuEChERS method were compared. Optimum results were followed by the addition of 1% acetic acid in acetonitrile; C18 sorbent was added due to the acidic nature of several pesticides. The recoveries of the pesticides were in the range 73.7-118.4%, with relative standard deviations lower than 16.63%. Limits of detection ranged from 0.1-1.0 μg/kg. The method presented here is simple, rapid, sensitive and can be applied to large-scale monitoring programs to screen the presences of pesticides in fruits.
authors: Laboratory of Chemistry and Physics, Hangzhou Center for Disease Control and Prevention, Hangzhou, P. R. China.
authors: Shaoying
authors: S
authors: Liu
authors: Laboratory of Chemistry and Physics, Hangzhou Center for Disease Control and Prevention, Hangzhou, P. R. China.
authors: Huali
authors: H
authors: He
authors: Laboratory of Chemistry and Physics, Hangzhou Center for Disease Control and Prevention, Hangzhou, P. R. China.
authors: Xihui
authors: X
authors: Huang
authors: Laboratory of Chemistry and Physics, Hangzhou Center for Disease Control and Prevention, Hangzhou, P. R. China.
authors: Quan
authors: Q
authors: Jin
authors: Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, P. R. China.
authors: Guonian
authors: G
authors: Zhu
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000191:economics; D005638:Fruit / Q000737:chemistry* / Q000191:economics; D005659:Fungicides, Industrial / Q000032:analysis* / Q000191:economics; D008278:Magnesium Sulfate / Q000737:chemistry*; D010573:Pesticide Residues / Q000032:analysis* / Q000191:economics; D010937:Plant Growth Regulators / Q000032:analysis* / Q000191:economics; D052616:Solid Phase Extraction / Q000191:economics; D012997:Solvents / Q000737:chemistry; D053719:Tandem Mass Spectrometry / Q000191:economics
chemical_list: D005659:Fungicides, Industrial; D010573:Pesticide Residues; D010937:Plant Growth Regulators; D012997:Solvents; D008278:Magnesium Sulfate
keywords: Fruit; Pesticides; Tandem mass spectrometry; Ultra high performance liquid chromatography