title: A Compact DNA Cube with Side Length 10 nm.
abstract: A small and compact DNA cube with zeptoliter volume is constructed by means of a generalized DNA brick concept using short synthetic oligonucleotides with varying lengths. By mimicking design principles from the DNA origami technique, the DNA cube offers higher stability and assembly yields compared to other approaches. Its potential application as nanoscale fluorescent probe is demonstrated using super-resolution imaging.
authors: Physics Department and ZNN/WSI, Technische Universität München, Am Coulombwall 4a, 85748, Garching, Germany.|Nanosystems Initiative Munich, Schellingstr. 4, 80799, München, Germany.
authors: Max B
authors: MB
authors: Scheible
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Cir, Boston, MA, 02115, USA.
authors: Luvena L
authors: LL
authors: Ong
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Cir, Boston, MA, 02115, USA.|Max Planck Institute of Biochemistry and LMU, Am Klopferspitz 18, 82152, Martinsried, Germany.
authors: Johannes B
authors: JB
authors: Woehrstein
authors: Max Planck Institute of Biochemistry and LMU, Am Klopferspitz 18, 82152, Martinsried, Germany.
authors: Ralf
authors: R
authors: Jungmann
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Cir, Boston, MA, 02115, USA.
authors: Peng
authors: P
authors: Yin
authors: Physics Department and ZNN/WSI, Technische Universität München, Am Coulombwall 4a, 85748, Garching, Germany.|Nanosystems Initiative Munich, Schellingstr. 4, 80799, München, Germany.
authors: Friedrich C
authors: FC
authors: Simmel
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure*; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size
chemical_list: D005456:Fluorescent Dyes; D004247:DNA
keywords: DNA bricks; DNA nanostructures; DNA-PAINT; super-resolution microscopy