title: Rendu-Osler-Weber syndrome: dermatological approach.
abstract: The Rendu-Osler-Weber syndrome is a rare systemic fibrovascular dysplasia, recognized by mucocutaneous telangiectasias, arteriovenous malformations, epistaxis and family history. Recurrent bleeding, hypoxemia, congestive heart failure, portosystemic encephalopathy, and symptoms related to angiodysplasia of the central nervous system may occur. Since the treatment is based on supportive measures, early recognition is of utmost importance. This article reports the case of a 53-year-old male patient who presented telangiectasias on fingers, oral cavity and nasal mucosa for 10 years, with a history of recurrent epistaxis of varying severity since childhood. Mother, sister and daughter have similar lesions.
authors: Hospital São Julião, Campo Grande, MS, BR.
authors: Aline Blanco
authors: AB
authors: Barbosa
authors: Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, BR.
authors: Günter
authors: G
authors: Hans Filho
authors: Hospital São Julião, Campo Grande, MS, BR.
authors: Carolina Faria dos Santos
authors: CF
authors: Vicari
authors: Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, BR.
authors: Marcelo Zanolli
authors: MZ
authors: Medeiros
authors: Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, BR.
authors: Daíne Vargas
authors: DV
authors: Couto
authors: Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, BR.
authors: Luiz Carlos
authors: LC
authors: Takita
mesh_terms: D004844:Epistaxis / Q000473:pathology*; D004935:Esophageal Diseases / Q000473:pathology; D030342:Genetic Diseases, Inborn / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013272:Stomach Diseases / Q000473:pathology; D013577:Syndrome; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000473:pathology*; D014060:Tongue Diseases / Q000473:pathology