title: Correlations of O3 therapeutic targets and imaging localization in lumbar intervertebral disc protrusion.
abstract: OBJECTIVE
  This study aims to investigate correlations between the effects of O3 target-injection treatment and imaging localization in lumbar intervertebral disc protrusion (LIDP).
  
  
  METHODS
  164 LIDP patients were divided into 3 groups: group A, the protrusion located at level I-III, region 1-2, domain a-b; group B, the protrusion located at level I-III, region 1-2, domain c-d; group C: the protrusion located at level I-III, region 3-4, domain a-b. The patients were treated with LIDP O3-target treatment + blocking therapy with epidural anti-inflammatory analgesic liquid.
  
  
  RESULTS
  Among the 164 LIDP patients, 95 patients (57.93%) exhibited the significant effectiveness after the treatment; 64 cases (39.02%) exhibited the effectiveness. The results of functional improvements revealed that 50 cases (53.76%) of sagittal plane and 54 cases of horizontal plane (55.67%) in the group A, 33 cases (35.48%) and 31 cases (31.96%) in the group C respectively were significantly better than those in the group B (10 cases, 10.75%; 12 cases, 12.37%) (P < 0.05). The visual analogue scale (VAS) scores 1 week and 1 month after the treatment in the three groups were significantly decreased than those before the treatment (P < 0.05). The intergroup comparison revealed that the A group (1 week 2.28 ± 0.85, 1 month 1.21 ± 0.27) and C (2.79 ± 0.98, 1.38 ± 0.55) were significantly better than the B group (3.92 ± 1.14, 2.53 ± 0.51) (P < 0.05).
  
  
  CONCLUSIONS
  The O3 target-injection treatment exhibited the best effects in treating the LIDP patients with the protrusion located at level I-III, region 1-2, domain a-b.
authors: Department of Pain, The Affiliated Hospital of Qingdao University Qingdao 266003, China.
authors: Fenghe
authors: F
authors: Xu
authors: Department of Pain, The Affiliated Hospital of Qingdao University Qingdao 266003, China.
authors: Yanwei
authors: Y
authors: Yin
authors: Department of Pain, The Affiliated Hospital of Qingdao University Qingdao 266003, China.
authors: Chuansheng
authors: C
authors: Liu
authors: Department of Pain, The Affiliated Hospital of Qingdao University Qingdao 266003, China.
authors: Yusheng
authors: Y
authors: Yi
authors: Department of Pain, The Affiliated Hospital of Qingdao University Qingdao 266003, China.
authors: Junmin
authors: J
authors: Yu
authors: Department of Pain, The Affiliated Hospital of Qingdao University Qingdao 266003, China.
authors: Dewei
authors: D
authors: Kou
authors: Department of Pain, The Affiliated Hospital of Qingdao University Qingdao 266003, China.
authors: Shijie
authors: S
authors: Wang
keywords: Lumbar intervertebral disc protrusion; O3 injection; imaging localization