title: Transformation of IGHV4-34+ hairy cell leukaemia-variant with U2AF1 mutation into a clonally-related high grade B-cell lymphoma responding to immunochemotherapy.
authors: Anatomic Pathology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors: Magda
authors: M
authors: Zanelli
authors: Anatomic Pathology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy. moira.ragazzi@asmn.re.it.
authors: Moira
authors: M
authors: Ragazzi
authors: Anatomic Pathology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors: Riccardo
authors: R
authors: Valli
authors: Institute of Haematology and C.R.E.O. (Centro di Ricerche Onco-Ematologiche), Ospedale S. Maria della Misericordia and University of Perugia, Perugia, Italy.
authors: Simonetta
authors: S
authors: Piattoni
authors: Haematology Unit, IRCCS Santa Maria Nuova Hospital, Reggio, Italy.
authors: Maria Isabel
authors: MI
authors: Alvarez De Celis
authors: Molecular Biology Unit, IRCCS Santa Maria Nuova, Reggio Emilia, Italy.
authors: Enrico
authors: E
authors: Farnetti
authors: Pathology Unit, IRCCS AOU San Martino-IST, Genova, Italy.
authors: Giulio Fraternali
authors: GF
authors: Orcioni
authors: Clinical Chemistry and Endocrinology Laboratory, Department of Diagnostic Imaging and Laboratory Medicine, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors: Rosina
authors: R
authors: Longo
authors: Institute of Pathology, Ospedale S. Maria di Terni and University of Perugia, Perugia, Italy.
authors: Stefano
authors: S
authors: Ascani
authors: Institute of Haematology and C.R.E.O. (Centro di Ricerche Onco-Ematologiche), Ospedale S. Maria della Misericordia and University of Perugia, Perugia, Italy.
authors: Brunangelo
authors: B
authors: Falini
authors: Institute of Haematology and C.R.E.O. (Centro di Ricerche Onco-Ematologiche), Ospedale S. Maria della Misericordia and University of Perugia, Perugia, Italy.
authors: Enrico
authors: E
authors: Tiacci
mesh_terms: D000368:Aged; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002999:Clone Cells; D050438:Genes, Immunoglobulin Heavy Chain; D014644:Genetic Variation; D006801:Humans; D007167:Immunotherapy; D007943:Leukemia, Hairy Cell / Q000235:genetics* / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000188:drug therapy* / Q000235:genetics; D008297:Male; D009154:Mutation; D012074:Remission Induction; D000072668:Splicing Factor U2AF / Q000235:genetics*; D016896:Treatment Outcome
chemical_list: D000072668:Splicing Factor U2AF; C076753:U2AF1 protein, human
keywords: IGHV4-34 rearrangement; U2AF1 mutation; cyclin D1; hairy-cell leukaemia variant; lymphoma transformation