title: Suppression of radiation damping for high precision quantitative NMR.
abstract: True quantitative analysis of concentrated samples by (1)H NMR is made very difficult by Radiation Damping. A novel NMR sequence (inspired by the WET NMR sequence and by Outer Volume Saturation methods) is therefore proposed to suppress this phenomenon by reducing the spatial area and consequently the number of spins contributing to the signal detected. The size of the detected volume can be easily chosen in a large range and line shape distortions are avoided thanks to a uniform signal suppression of the outer volume. Composition of a mixture can as a result be determined with very high accuracy (precision and trueness) at the per mille level whatever the concentrations and without hardware modification.
authors: EBSI team, Interdisciplinary Chemistry: Synthesis, Analysis, Modeling (CEISAM), University of Nantes-CNRS UMR 6230, 2 rue de la Houssinière, BP 92208, F-44322 Nantes cedex 3, France.
authors: Kevin
authors: K
authors: Bayle
authors: EBSI team, Interdisciplinary Chemistry: Synthesis, Analysis, Modeling (CEISAM), University of Nantes-CNRS UMR 6230, 2 rue de la Houssinière, BP 92208, F-44322 Nantes cedex 3, France.
authors: Maxime
authors: M
authors: Julien
authors: EBSI team, Interdisciplinary Chemistry: Synthesis, Analysis, Modeling (CEISAM), University of Nantes-CNRS UMR 6230, 2 rue de la Houssinière, BP 92208, F-44322 Nantes cedex 3, France.
authors: Gérald S
authors: GS
authors: Remaud
authors: EBSI team, Interdisciplinary Chemistry: Synthesis, Analysis, Modeling (CEISAM), University of Nantes-CNRS UMR 6230, 2 rue de la Houssinière, BP 92208, F-44322 Nantes cedex 3, France. Electronic address: serge.akoka@univ-nantes.fr.
authors: Serge
authors: S
authors: Akoka
keywords: Quantitative NMR; Radiation damping