title: [Contributions of human rods and cones pathway to different components of oscillatory potentials in time and frequency domain].
abstract: OBJECTIVE
  To investigate the contributions of human rods and cones pathway to different components of oscillatory potentials (OP) in time and frequency domain.
  
  
  METHODS
  Case-control study. Twenty subjects were divided into two groups, normal groups (NG) and cones pathway abnormal groups (CAG). All eyes were investigated by dark-adapted (DA) and light-adapted (LA) 3.0 ERG recommended by ISCEV. Data were output into the computer and processed and analyzed by the software Matlab7.0. First, to extract the OP by filter, then to get the frequency-amplitude relationship by FFT, after that the relationship was fitted by equations and lastly we statistic and analyze the parameters gotten from the equations.
  
  
  RESULTS
  Compared with normal group [(48.63 ± 4.29), (158.00 ± 32.75), (69.27 ± 30.31), (38.5 ± 15.28) µV], the amplitudes of the first two components of dark-adapted OP in the CAG [(4.12 ± 3.20), (71.25 ± 25.43), (48.96 ± 20.05), (36.84 ± 14.26) µV] were significant decreased (t = 16.68, 5.77, P < 0.01). Frequency domain of LA and DA OP in the two groups was comprised with two components (harmonic and subharmonic). Compared with normal group, harmonic components of CAG were dramatic decreased (t = 2.72, P < 0.05; Z = -2.24, P < 0.05). The value of subharmonic component in CAG was lowest in DA OP compared with NG (t = 4.20, P < 0.005).
  
  
  CONCLUSIONS
  Cones and rods pathway all contributed to the DA and LA OP Cones pathway mainly contributes to the earlier and faster components of OP while the rods pathway to the later and slower components.
authors: Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, Chongqing 400038, China.
authors: Jiaman
authors: J
authors: Dai
authors: Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, Chongqing 400038, China; Email: shiying_li@126.com.
authors: Shiying
authors: S
authors: Li
authors: Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, Chongqing 400038, China.
authors: Zhengqin
authors: Z
authors: Yin
authors: Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, Chongqing 400038, China.
authors: Gang
authors: G
authors: Wang
authors: Southwest Hospital, Southwest Eye Hospital, Third Military Medical University, Chongqing 400038, China.
authors: Xiaohong
authors: X
authors: Meng
mesh_terms: D000221:Adaptation, Ocular; D016022:Case-Control Studies; D003623:Dark Adaptation; D004596:Electroretinography; D006801:Humans; D017949:Retinal Cone Photoreceptor Cells / Q000502:physiology*; D017948:Retinal Rod Photoreceptor Cells / Q000502:physiology*