title: [DIETARY INTAKE AND NUTRITIONAL STATUS IN ONCOLOGY PATIENTS WHO START TREATMENT WITH TYROSINE KINASE INHIBITORS].
abstract: BACKGROUND
  in recent years, researching about new oral antineoplastics has progressed while its impact on dietary intake and nutritional status (NS) hasn't developed enough yet.
  
  
  OBJECTIVE
  dietary intake and NS assessment in patients who start treatment with tyrosine kinase inhibitors (TKI) and evaluate its impact on them.
  
  
  METHODS
  an observational, prospective-six-months study, in which were included patients starting treatment with TKI. The intake was evaluated by a 24 h dietary record and a food frequency questionnaire. The NS was evaluated by anthropometric measurements and the patient-generated Global Subjective Assessment (PG-GSA); the results were compared with the Spanish references (SENC-semFYC, 2007 and O. Moreiras, 2013). Friedman test, χ2, Wilcoxon, Kruskal-Wallis and Mann-Whitney were used in the statistical analysis. Significance p < 0.05.
  
  
  RESULTS
  22 patients (54.5% male) were included. At baseline, NS was adequate in 73.9% of patients according PG-GSA. Weight loss was no significant, although a high percentage of the energy and protein requirements hadn't been reached. The caloric intake was positively related with the number of meals. Dietary habits did not change during treatment.
  
  
  CONCLUSIONS
  dietary intake did not reach nutritional requirements at baseline. The TKI don't seem to affect the patient's intake and nutritional status. The research about these parameters before starting treatment could prevent future complications and it would guide the dietary advice.
authors: Unidad de Nutrición Clínica y Dietética. Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid.. ihiguera86@gmail.com.
authors: Isabel
authors: I
authors: Higuera-Pulgar
authors: Servicio de Farmacia. Hospital General Universitario Gregorio Marañón, Madrid (España).. ihiguera86@gmail.com.
authors: Almudena
authors: A
authors: Ribed
authors: Unidad de Nutrición Clínica y Dietética. Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid.. ihiguera86@gmail.com.
authors: M Luisa
authors: ML
authors: Carrascal-Fabian
authors: Unidad de Nutrición Clínica y Dietética. Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid.. ihiguera86@gmail.com.
authors: Irene
authors: I
authors: Bretón-Lesmes
authors: Servicio de Farmacia. Hospital General Universitario Gregorio Marañón, Madrid (España).. ihiguera86@gmail.com.
authors: Rosa M
authors: RM
authors: Romero-Jiménez
authors: Unidad de Nutrición Clínica y Dietética. Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid.. ihiguera86@gmail.com.
authors: Cristina
authors: C
authors: Cuerda-Compes
authors: Unidad de Nutrición Clínica y Dietética. Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid.. ihiguera86@gmail.com.
authors: Cristina
authors: C
authors: Velasco-Gimeno
authors: Unidad de Nutrición Clínica y Dietética. Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid.. ihiguera86@gmail.com.
authors: Miguel
authors: M
authors: Camblor-Álvarez
authors: Unidad de Nutrición Clínica y Dietética. Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón, Madrid.. ihiguera86@gmail.com.
authors: Pilar
authors: P
authors: García-Peris
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001837:Body Weights and Measures; D004032:Diet; D015930:Diet Records; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000188:drug therapy*; D015596:Nutrition Assessment; D009751:Nutritional Requirements; D009752:Nutritional Status; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors