title: Craniotomy for Resection of Meningioma: An Age-Stratified Analysis of the MarketScan Longitudinal Database.
abstract: OBJECTIVE
  We sought to describe complications after resection for meningioma with the use of longitudinal administrative data, which our group has shown recently to be superior to nonlongitudinal administrative data.
  
  
  METHODS
  We identified patients who underwent resection for meningioma between 2010 and 2012 in the Thomson Reuters MarketScan database. Current Procedural Terminology coding at inpatient visit was used to select for meningioma resection procedure. Comorbidities and complications were obtained by use of the International Classification of Diseases, Ninth Revision or Current Procedural Terminology coding. Associations between complications and demographic and clinical factors were evaluated with logistic regression.
  
  
  RESULTS
  We identified a total of 2216 patients. Approximately 41% developed 1 or more perioperative complications. Approximately 15% were readmitted within 30 days of their procedure. The most frequent complications that occurred in our cohort were new postoperative seizures (11.8%), postoperative dysrhythmia (7.9%), intracranial hemorrhage (5.9%), and cerebral artery occlusion (5.4%). General neurosurgical complications and general neurologic complications occurred in 4.4% and 16.1% of patients, respectively. Nearly 55% of elderly patients (≥ 70 years) developed 1 or more perioperative complication (vs. 39% of nonelderly patients). After we adjusted for comorbidities, elderly status and male sex were found to be significantly associated with increased odds for a variety of complications.
  
  
  CONCLUSIONS
  In this study, we report complication rates in patients undergoing resection for meningioma. Because of the longitudinal nature of the MarketScan database, we were able to capture a wide array of specific postoperative complications associated with meningioma resection procedures. Care should be taken in the selection of candidates for meningioma resection.
authors: Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA.
authors: Ian D
authors: ID
authors: Connolly
authors: Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA.
authors: Tyler
authors: T
authors: Cole
authors: Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA.
authors: Anand
authors: A
authors: Veeravagu
authors: Division of Epidemiology, Department of Health Research and Policy, Stanford University, Stanford, California, USA.
authors: Rita
authors: R
authors: Popat
authors: Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA.
authors: John
authors: J
authors: Ratliff
authors: Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA. Electronic address: gordonli@stanford.edu.
authors: Gordon
authors: G
authors: Li
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology; D001157:Arterial Occlusive Diseases / Q000209:etiology; D002536:Cerebral Arteries / Q000473:pathology; D003399:Craniotomy / Q000009:adverse effects; D016208:Databases, Factual; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology; D016015:Logistic Models; D008297:Male; D008577:Meningeal Neoplasms / Q000601:surgery*; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D012640:Seizures / Q000209:etiology; D012737:Sex Factors; D014481:United States
keywords: Adverse events; Craniotomy; MarketScan; Meningioma