title: Breast magnetic resonance imaging (MRI) surveillance in breast cancer survivors.
abstract: OBJECTIVE
  As the breast cancer survivor population increases, the topic of screening these women for recurrences is increasingly relevant. In our institution, we use both breast MRI and mammography in the surveillance of breast cancer survivors, although little data exists on the use of MRI in this setting. We present a retrospective analysis of our experience and compare the sensitivity and specificity of MRI vs. mammography in this setting.
  
  
  METHODS
  We identified women under 65 with a history of breast cancer and at least one follow-up MRI performed along with a mammogram done within 6 months of the MRI. We compared the outcomes of MRI and mammography in terms of biopsies performed as well as in detection of new cancers.
  
  
  RESULTS
  Of 617 charts reviewed, 249 patients met inclusion criteria, with 571 paired MRI/mammogram results. There were 27 biopsies performed due to MRI findings alone, 10 done due to mammographic findings alone, and 15 done based on abnormalities seen on both imaging modalities. There were 8 malignancies identified based on an abnormal MRI, 3 detected on both MRI and mammography, and none identified via mammography alone. Overall, MRI had a sensitivity of 84.6% (the 95% CI 54.6-98.1) and a specificity of 95.3% (the 95% CI 93.3-96.9); mammography a sensitivity of 23.1% (the 95% CI 5.0-53.8), and a specificity of 96.4% (the 95% CI 94.5-97.8).
  
  
  CONCLUSIONS
  Breast MRI is a useful surveillance modality in breast cancer survivors and may be more sensitive at detecting recurrences than mammography alone in this population.
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Chana
authors: C
authors: Weinstock
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Cristina
authors: C
authors: Campassi
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Olga
authors: O
authors: Goloubeva
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Kathleen
authors: K
authors: Wooten
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Susan
authors: S
authors: Kesmodel
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Emily
authors: E
authors: Bellevance
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Steven
authors: S
authors: Feigenberg
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Olga
authors: O
authors: Ioffe
authors: University of Maryland Greenebaum Cancer Center, 22 South Greene Street, RM S9D, Baltimore, MD 21201 USA.
authors: Katherine H R
authors: KH
authors: Tkaczuk
keywords: Bilateral; Breast cancer; Magnetic resonance imaging; Surveillance