title: Magnetic octadecyl-based matrix solid-phase dispersion coupled with gas chromatography with mass spectrometry in a proof-of-concept determination of multi-class pesticide residues in carrots.
abstract: A novel procedure is put forward based on the combination of the well-established matrix solid-phase dispersion and the magnetic and sorption properties of magnetic octadecyl in the presence of n-octanol and was employed in a proof-of-concept sample preparation and determination of several classes of pesticide residues in carrots. The procedure does not require the transfer of blend to cartridge and subsequent packing, nor any co-sorbent for extract clean up. The hydrophobic magnetic nanoparticles utilized as a sorbent, can be retrieved by n-octanol under the application of a magnetic field due to hydrophobic interactions. Elution of pesticide residues is then carried out with an organic solvent. A total of 26 pesticides were included in this procedure and the target compounds were analyzed using gas chromatography with mass spectrometry in the selective ion monitoring mode. The average extraction recoveries obtained from carrot samples fortified at three different concentrations (20, 50, and 500 μg/kg) were 77-107%. The estimated limits of quantitation for most target analytes were in the low μg/kg level. The study demonstrates that the proposed extraction procedure is simple and effective, avoiding a clean-up step for the sample preparation of vegetable.
authors: Department of Chemistry, University of Ioannina, Ioannina, Greece.
authors: Charalampos S
authors: CS
authors: Binellas
authors: Department of Chemistry, University of Ioannina, Ioannina, Greece.
authors: Constantine D
authors: CD
authors: Stalikas
keywords: Carrots; Gas chromatography with mass spectrometry; Magnetic octadecyl nanosorbent; Matrix solid-phase dispersion; Pesticide residues