title: Imaging of prehospital stroke therapeutics.
abstract: Despite significant quality improvement efforts to streamline in-hospital acute stroke care in the conventional model, there remain inherent layers of treatment delays, which could be eliminated with prehospital diagnostics and therapeutics administered in a mobile stroke unit. Early diagnosis using telestroke and neuroimaging while in the ambulance may enable targeted routing to hospitals with specialized care, which will likely improve patient outcomes. Key clinical trials in telestroke, mobile stroke units with prehospital neuroimaging capability, prehospital ultrasound and co-administration of various classes of neuroprotectives, antiplatelets and antithrombin agents with intravenous thrombolysis are discussed in this article.
authors: a 1 Department of Neurology, University of Southern California, Los Angeles, CA, USA.
authors: Michelle P
authors: MP
authors: Lin
authors: Nerses
authors: N
authors: Sanossian
authors: David S
authors: DS
authors: Liebeskind
mesh_terms: D000552:Ambulances; D000818:Animals; D000959:Antihypertensive Agents / Q000008:administration & dosage; D004632:Emergency Medical Services; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D018696:Neuroprotective Agents / Q000008:administration & dosage; D020521:Stroke / Q000175:diagnosis* / Q000628:therapy*; D017216:Telemedicine; D013997:Time Factors
chemical_list: D000959:Antihypertensive Agents; D005343:Fibrinolytic Agents; D018696:Neuroprotective Agents
keywords: mobile stroke unit; prehospital therapeutics; stroke; telemedicine; thrombolysis