title: Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy.
abstract: We quantitatively estimated dosimetric variations due to interfraction organ deformation in multi-fractionated high-dose-rate brachytherapy (HDRBT) for cervical cancer using a novel surface-based non-rigid deformable registration. As the number of consecutive HDRBT fractions increased, simple addition of dose-volume histogram parameters significantly overestimated the dose, compared with distribution-based dose addition.
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan. Electronic address: kazumkob@ncc.go.jp.
authors: Kazuma
authors: K
authors: Kobayashi
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Naoya
authors: N
authors: Murakami
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Akihisa
authors: A
authors: Wakita
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Satoshi
authors: S
authors: Nakamura
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Hiroyuki
authors: H
authors: Okamoto
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Rei
authors: R
authors: Umezawa
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Kana
authors: K
authors: Takahashi
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Koji
authors: K
authors: Inaba
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Hiroshi
authors: H
authors: Igaki
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Yoshinori
authors: Y
authors: Ito
authors: Department of Radiology, Keio University School of Medicine, Shinjuku-ku, Japan.
authors: Naoyuki
authors: N
authors: Shigematsu
authors: Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Japan.
authors: Jun
authors: J
authors: Itami
mesh_terms: D001918:Brachytherapy; D005260:Female; D006801:Humans; D011879:Radiotherapy Dosage; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy*
keywords: Brachytherapy; Cervical cancer; Deformable registration; Dose evaluation; Interfraction variation