title: [Prevalence of granulomatous lesions in minor salivary gland biopsy in a case series of 65 patients with tuberculosis].
abstract: OBJECTIVE
  The distinction between tuberculosis (TB), a worldwide infectious granulomatosis requiring specific antibiotic therapy, and sarcoidosis, a rare granulomatous disease that may require corticosteroids is not straightforward and may result in diagnostic and therapeutic delay.
  
  
  METHODS
  We prospectively and consecutively evaluated the presence of epithelioid granulomas in minor salivary gland biopsy of 65 consecutive patients with TB.
  
  
  RESULTS
  In our study, 10.8 % of our TB patients had epithelioid granulomas without caseous necrosis identified in their minor salivary gland biopsy, regardless of the location of TB, HIV status and whether or not the sputum examination was positive for tuberculous bacilli.
  
  
  CONCLUSIONS
  The presence of epithelioid granulomas in minor salivary gland biopsy may not be helpful to the clinician to rule out TB in a patient with suspected sarcoidosis.
authors: Service de médecine interne A, université Sorbonne Paris Cité-Diderot, groupe hospitalier Lariboisière-Fernand-Widal, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: veronique.delcey@aphp.fr.
authors: V
authors: V
authors: Delcey
authors: Service de médecine interne A, université Sorbonne Paris Cité-Diderot, groupe hospitalier Lariboisière-Fernand-Widal, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France.
authors: M
authors: M
authors: Morgand
authors: Service de médecine interne A, université Sorbonne Paris Cité-Diderot, groupe hospitalier Lariboisière-Fernand-Widal, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France.
authors: A
authors: A
authors: Lopes
authors: Service de médecine interne A, université Sorbonne Paris Cité-Diderot, groupe hospitalier Lariboisière-Fernand-Widal, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France.
authors: S
authors: S
authors: Mouly
authors: Service de médecine interne A, université Sorbonne Paris Cité-Diderot, groupe hospitalier Lariboisière-Fernand-Widal, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France.
authors: I
authors: I
authors: Jarrin
authors: Service de médecine interne A, université Sorbonne Paris Cité-Diderot, groupe hospitalier Lariboisière-Fernand-Widal, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France.
authors: P
authors: P
authors: Sellier
authors: Service d'anatomopathologie, université Sorbonne Paris Cité-Diderot, groupe hospitalier Lariboisière-Fernand-Widal, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France.
authors: M
authors: M
authors: Wassef
authors: Service de médecine interne A, université Sorbonne Paris Cité-Diderot, groupe hospitalier Lariboisière-Fernand-Widal, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France.
authors: J-F
authors: JF
authors: Bergmann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012466:Salivary Gland Diseases / Q000453:epidemiology / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000473:pathology; D012507:Sarcoidosis / Q000175:diagnosis / Q000473:pathology*; D014376:Tuberculosis / Q000453:epidemiology / Q000473:pathology*; D055815:Young Adult
keywords: Biopsies de glandes salivaires accessoires; Granulomatose; Granulomatosis; Granulomatous lesions; Granulome; Minor salivary gland biopsy; Sarcoidosis; Sarcoïdose; Tuberculose; Tuberculosis