title: Effect of suction on macular thickness and retinal nerve fiber layer thickness during LASIK used femtosecond laser and Moria M2 microkeratome.
abstract: OBJECTIVE
  To compare the effect of suction on the macular thickness and retinal nerve fiber layer (RNFL) thickness during laser in situ keratomileusis (LASIK) used Ziemer FEMTO LDV femtosecond laser (Ziemer group) and Moria M2 automated microkeratome (Moria group) for flap creation.
  
  
  METHODS
  Fourier-domain optical coherence tomography (FD-OCT) was used to measure macular thickness, ganglion cell complex thickness and (RNFL) thickness of 204 eyes of 102 patients with the Ziemer femtosecond laser (102 eyes) and the Moria M2 microkeratome (102 eyes) before surgery and 30min; 1, 3d; 1wk; 1, 3mo; 1y after surgery.
  
  
  RESULTS
  The average foveal thickness and parafoveal retinal thickness 30min after the surgery were statistically more than that before surgery (Ziemer P<0.001, P=0.003 and Moria P=0.001, P=0.006) and the effect was less in the Ziemer group than that in the Moria group (P all<0.05). The ganglion cell complex thickness was not significantly changed in both groups (P all>0.05). The RNFL thickness was statistically less 30min after surgery in both groups (P=0.014, P<0.001), but the influence was less in Ziemer group than that in Moria group (P=0.038). However, the RNFL thickness had recovered to the preoperative level only 1d after surgery.
  
  
  CONCLUSIONS
  The suction of femtosecond laser and mechanical microkeratome led to the increase in macular central fovea thickness and the decrease in RNFL thickness values at the early stage after LASIK. The effect of suction on macular and the RNFL thicknesses in Ziemer group is smaller than that in Moria group.
authors: Ophthalmic Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors: Jing
authors: J
authors: Zhang
authors: Ophthalmic Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors: Yue-Hua
authors: YH
authors: Zhou
keywords: femtosecond laser; laser in situ keratomileusis; macular; optical coherence tomography; retinal nerve fiber layer