title: Preliminary results of non-contact THz imaging of cornea.
abstract: This paper presents a novel THz optical design that allows the acquisition of THz reflectivity maps ofin vivocornea without the need for a field flattening window and preliminary imaging results of in vivo rabbit cornea. The system's intended use is to sense small changes in corneal tissue water content (CTWC) that can be precursors for a host of diseases and pathologies. Unique beam optics allows the scanning of a curved surface at normal incidence while keeping the source detector and target stationary. Basic system design principles are discussed and image sets of spherical calibration targets and corneal phantom models are presented. The presented design will enable, for the first time, non-contact THz imaging of animal and human cornea.
authors: Dept. of Electrical Engineering, UCLA, 420 Westwood Plaza, Los Angeles, CA, USA 90095.
authors: Shijun
authors: S
authors: Sung
authors: Dept. of Bioengineering, UCLA, 420 Westwood Plaza, Los Angeles, CA, USA 90095.
authors: James
authors: J
authors: Garritano
authors: Dept. of Bioengineering, UCLA, 420 Westwood Plaza, Los Angeles, CA, USA 90095.
authors: Neha
authors: N
authors: Bajwa
authors: Dept. of Ophthalmology, UCLA, 200 UCLA Medical Plaza, Los Angeles, CA, USA 90095.
authors: Sophie
authors: S
authors: Deng
authors: Dept. of Ophthalmology, UCLA, 200 UCLA Medical Plaza, Los Angeles, CA, USA 90095.
authors: Jean-Pierre
authors: JP
authors: Hubschman
authors: Dept. of Electrical Engineering, UCLA, 420 Westwood Plaza, Los Angeles, CA, USA 90095 ; Dept. of Bioengineering, UCLA, 420 Westwood Plaza, Los Angeles, CA, USA 90095 ; Dept. of Surgery, UCLA, 200 UCLA Medical Plaza, Los Angeles, CA, USA 90095.
authors: Warren S
authors: WS
authors: Grundfest
authors: Dept. of Bioengineering, UCLA, 420 Westwood Plaza, Los Angeles, CA, USA 90095 ; Dept. of Surgery, UCLA, 200 UCLA Medical Plaza, Los Angeles, CA, USA 90095.
authors: Zachary D
authors: ZD
authors: Taylor
keywords: THz medical imaging; optical design; quasioptics