title: Zoon's balanitis successfully treated with photodynamic therapy: Case report and literature review.
abstract: Zoon's balanitis (ZB) is an idiopathic chronic condition usually presenting as a solitary erythematous plaque on the glans of primarily uncircumcised, middle-aged to older men. The different treatment options for this condition often achieve partial results, with frequent recurrence after treatment withdrawal. Recently, photodynamic therapy (PDT) has been proposed as therapeutic option with discordant results. We treated a thirty-five year-old man affected by Zoon's balanitis, resistant to conventional treatments, with 3 sessions of topical ALA-PDT at two weeks intervals. At the end of the treatment period notable improvement of clinical features was observed, with almost complete clearance at 3 months' follow-up, high safety profile and absence of durable side-effects.
authors: Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Italy. Electronic address: fborgia@unime.it.
authors: Francesco
authors: F
authors: Borgia
authors: Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Italy.
authors: Mario
authors: M
authors: Vaccaro
authors: Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Italy.
authors: Antonio
authors: A
authors: Foti
authors: Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Italy.
authors: Roberta
authors: R
authors: Giuffrida
authors: Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Italy.
authors: Serafinella P
authors: SP
authors: Cannavò
mesh_terms: D000328:Adult; D000622:Aminolevulinic Acid / Q000008:administration & dosage*; D001446:Balanitis / Q000188:drug therapy* / Q000473:pathology*; D019317:Evidence-Based Medicine; D006801:Humans; D008297:Male; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid
keywords: Balanitis; Inflammation; Photodynamic therapy; Review