title: Early T Stage Salivary Duct Carcinoma: Outcomes and Implications for Patient Counseling.
abstract: Salivary duct carcinoma (SDC) is a rare salivary malignancy that often presents at advanced stage. Outcomes of low T stage patients with SDC have not been previously examined in detail. We queried our institution's cancer database and identified 28 patients with SDC in situ or T1/T2 SDC. A retrospective chart review was performed, followed by comparison of clinicopathologic features with N stage, disease-free survival, and overall survival. Patients tended to be male, in their sixties, with a high incidence of regional metastases, as in prior reports. Five-year disease-free and overall survival were 49%. Median disease-free survival was 3.24 years, and overall survival was 4.65 years. Parotid location, vascular invasion, facial nerve sacrifice, and extracapsular extension were associated with worse survival. This study provides practical information for counseling of patients who undergo surgery for a parotid mass and are found to have this aggressive malignancy.
authors: Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA.
authors: Nicole C
authors: NC
authors: Schmitt
authors: Division of Otolaryngology-Head and Neck Surgery, Southern Illinois University, Springfield, Illinois, USA.
authors: Arun
authors: A
authors: Sharma
authors: Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
authors: Mark R
authors: MR
authors: Gilbert
authors: Department of Otolaryngology-Head and Neck Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA kimsw2@upmc.edu.
authors: Seungwon
authors: S
authors: Kim
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D003376:Counseling; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D018987:Salivary Ducts / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
keywords: salivary duct carcinoma; salivary malignancy