title: IgG4-related disease: description of a case with pulmonary lesions, mediastinal lymphadenopathies and rapidly progressive renal failure.
abstract: This is a case report of a 73-year-old man with new-onset acute renal failure while being investigated for pulmonary infiltrates and mediastinal lymphadenopathies. Urine tests showed tubular range proteinuria with no microhaematuria. Immunology tests showed elevated serum IgG and hypocomplementaemia (classical pathway activation). Renal biopsy and clinical-pathological correlation were crucial in this case, reinforcing their important role in the final diagnosis of acute kidney injury.
authors: Servicio de Nefrología. Complejo Hospitalario de Navarra. Pamplona, Navarra España. Electronic address: ml.fernandez.lorente@navarra.es.
authors: Loreto
authors: L
authors: Fernández Lorente
authors: Servicio de Anatomía Patológica. Hospital Germans Trias i Pujol. Badalona, Barcelona España.
authors: Dolores López
authors: DL
authors: Álvarez
authors: Servicio de Inmunología. Hospital Germans Trias i Pujol. Badalona, Barcelona España.
authors: Virginia García
authors: VG
authors: López
authors: Servicio de Nefrología. Hospital Germans Trias i Pujol. Badalona, Barcelona España.
authors: Vesna Abujder
authors: VA
authors: Kollros
authors: Servicio de Anatomía Patológica. Hospital Germans Trias i Pujol. Badalona, Barcelona España.
authors: Aurelio
authors: A
authors: Ariza
authors: Servicio de Medicina Interna. Hospital de Calella. Calella, Barcelona España.
authors: Alejandro
authors: A
authors: Gálvez
authors: Servicio de Nefrología. Hospital Germans Trias i Pujol. Badalona, Barcelona España.
authors: Josep
authors: J
authors: Bonet
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D001327:Autoimmune Diseases / Q000209:etiology* / Q000473:pathology; D001706:Biopsy; D002100:Cachexia / Q000209:etiology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008171:Lung Diseases / Q000209:etiology*; D000072281:Lymphadenopathy / Q000209:etiology*; D008297:Male; D008482:Mediastinum; D010265:Paraproteinemias / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D010950:Plasma Cells / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones; D007074:Immunoglobulin G
keywords: Enfermedad relacionada con IgG4; IgG4 related disease; Immunology; Inmunología; Insuficiencia renal rápidamente; Rapidly progressive renal failure; progresiva