title: Approaches to Study Human T Cell Development.
abstract: Not only is human T cell development characterized by unique changes in surface marker expression, but it also requires specific growth factors and conditions to mimic and study T cell development in vitro. In this chapter, we provide an overview of the specific aspects that need attention when performing T cell differentiation cultures with human progenitors.
authors: The Department of Clinical Chemistry, Microbiology and Immunology, Faculty of Medicine and Health Sciences, Ghent University Hospital, Ghent University, De Pintelaan 185 Blok A-4, 9000, Ghent, Belgium.
authors: Anne-Catherine
authors: AC
authors: Dolens
authors: Inge
authors: I
authors: Van de Walle
authors: Tom
authors: T
authors: Taghon
mesh_terms: D018929:Cell Culture Techniques; D002454:Cell Differentiation; D018920:Coculture Techniques; D005822:Genetic Vectors / Q000235:genetics; D006801:Humans; D054503:Lymphoid Progenitor Cells / Q000166:cytology* / Q000378:metabolism*; D012190:Retroviridae / Q000235:genetics; D013601:T-Lymphocytes / Q000166:cytology* / Q000378:metabolism*; D014161:Transduction, Genetic