title: WEIGHT LOSS AND METABOLIC OUTCOMES 12 MONTHS AFTER ROUX-EN-Y GASTRIC BYPASS IN A POPULATION OF SOUTHEASTERN BRAZIL.
abstract: BACKGROUNGD: previous outcome research in bariatric surgery has to document positive changes in co-morbidities associated with obesity.
  
  
  OBJECTIVE
  the study aimed report a description of the impact of bariatric surgery on weight loss and on the resolution of diseases associated with obesity in patients followed up for 12 months in the public health service of São Paulo/Brazil.
  
  
  METHODS
  the study was conducted on the data for 598 selected patients with grade III obesity subjected to Rouxen- Y gastric bypass evaluated postoperatively and 6 and 12 months after surgery. Anthropometric, demographic and biochemical data and personal history were determined at each time point. Serum glucose, total cholesterol, LDL cholesterol, HDL cholesterol and triglycerides were determined in the biochemical evaluation. Data were analyzed statistically by the Chi-square test, by ANOVA followed by the Bonferroni post-test and by the Student t-test for independent data, significance set at p < 0.05.
  
  
  RESULTS
  weight loss of 45.5 ± 13.7kg (33.5%) was observed during the first year after surgery. Serum glucose, total cholesterol and LDL cholesterol were reduced during the first six months after surgery and the values were maintained up to 12 months, whereas weight and triglycerides were reduced throughout the study period. A reduced prevalence of diabetes mellitus and dyslipidemia was observed after surgery (p < 0.001).
  
  
  CONCLUSIONS
  Roux-en-Y gastric bypass is an important procedure for weight loss and control of comorbidities such as diabetes and dyslipidemia at least during the first postoperative year.
authors: Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto, University of São Paulo, Ribeirao Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Marcela A S
authors: MA
authors: Pinhel
authors: Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto, University of São Paulo, Ribeirao Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Carolina F
authors: CF
authors: Nicoletti
authors: Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto, University of São Paulo, Ribeirao Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Bruno A P
authors: BA
authors: de Oliveira
authors: Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto, University of São Paulo, Ribeirao Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Raoana Cássia Paixão
authors: RC
authors: Chaves
authors: Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto, University of São Paulo, Ribeirao Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Luciana Tabajara
authors: LT
authors: Parreiras
authors: Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Thiago
authors: T
authors: Sivieri
authors: Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Vinicius M C
authors: VM
authors: Vulcano
authors: Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Gabriela R L
authors: GR
authors: Luz
authors: Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Danielle R
authors: DR
authors: Annunciato
authors: Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Luiza M A
authors: LM
authors: Morgado
authors: Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Gustavo
authors: G
authors: Marcatto
authors: Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto, University of São Paulo, Ribeirao Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Wilson
authors: W
authors: Salgado Junior
authors: Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Dorotéia R S
authors: DR
authors: Souza
authors: Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto, University of São Paulo, Ribeirao Preto - SP (Brazil).. carol_nicolettif@yahoo.com.br.
authors: Carla Barbosa
authors: CB
authors: Nonino
mesh_terms: D000328:Adult; D050110:Bariatric Surgery; D015415:Biomarkers; D001938:Brazil / Q000453:epidemiology; D015897:Comorbidity; D004734:Energy Metabolism; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D010535:Laparoscopy; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000453:epidemiology* / Q000378:metabolism / Q000601:surgery; D011184:Postoperative Period; D015995:Prevalence; D062486:Public Health Surveillance; D013997:Time Factors; D016896:Treatment Outcome; D015431:Weight Loss
chemical_list: D015415:Biomarkers