title: Measuring how genetic and epigenetic variants can filter emotion perception.
abstract: Emotion perception has been extensively studied in cognitive neurosciences and stands as a promising intermediate phenotype of social cognitive processes and psychopathologies. Exciting imaging genetic studies have recently identified genetic and epigenetic variants affecting brain responses during emotion perception tasks, but characterizing how these variants interact and relate to higher-order cognitive processes remains a challenge. Here, we integrate works in parallel fields and propose a new psychophysical conceptualization to address this issue. This approach proposes to consider genetic variants as 'filters' of perceptual information that can interact to shape different perceptual profiles. Importantly, these perceptual profiles can be precisely described and compared between multivariate genetic groups using a new psychophysical method. Crucially, this approach represents a potentially powerful novel tool to address gene-by-gene and gene-by-environment interactions, and provides a new cognitive perspective to link social perceptive and social cognitive processes in the context of psychiatric disorders.
authors: aSchool of Psychology, Université Laval bDepartment of Psychiatry and Neurosciences, Université Laval cCenter for Interdisciplinary Research in Rehabilitation and Social Integration (CIRRIS) dCentre de recherche de l'institut universitaire en santé mentale de Québec (CRIUSMQ), Québec, Canada eHuman Neuroimaging Laboratory, Virginia Tech Carilion Research Institute, Roanoke, Virginia, USA.
authors: Vincent
authors: V
authors: Taschereau-Dumouchel
authors: Sébastien
authors: S
authors: Hétu
authors: Yvon C
authors: YC
authors: Chagnon
authors: Philip L
authors: PL
authors: Jackson
mesh_terms: D001921:Brain / Q000502:physiology; D003071:Cognition / Q000502:physiology; D004644:Emotions / Q000502:physiology*; D044127:Epigenesis, Genetic; D004843:Epistasis, Genetic; D059647:Gene-Environment Interaction; D014644:Genetic Variation; D006801:Humans