title: Deciphering the biochemistry and identifying biomarkers to multiple sclerosis.
abstract: Multiple sclerosis is an idiopathic demyelinating disease of the CNS. Despite being extensively studied during the last decades, many molecular aspects of the disease are still to be elucidated. Moreover, biomarkers for treatment and early diagnosis are major issues to be tackled. In this edition of Kroksveen et al. (Proteomics 2015, 15, 3361-3369) present biomarker candidates for the early detection of multiple sclerosis. Despite the need for validation in larger sets of samples, this dataset contributes to resolve open questions associated to multiple sclerosis.
authors: UNICAMP's Neurobiology Center, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.|Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors: Daniel
authors: D
authors: Martins-de-Souza
authors: UNICAMP's Neurobiology Center, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.|Neuroimmunology Unit, Department of Genetics, Evolution, and Bioagents, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors: Alessandro S
authors: AS
authors: Farias
mesh_terms: D053378:Chromogranin B / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid*
chemical_list: D053378:Chromogranin B
keywords: Biomarkers; Cerebrospinal fluid; Multiple sclerosis; Quantitative MS; Secretogranin-1