title: Segmental Darier's disease: a presentation of difficult diagnosis.
abstract: Darier's disease is a rare autosomal dominant genodermatosis. It has an estimated prevalence of 1 in 55,000 to 100,000 individuals, regardless of gender. It is characterized by multiple keratotic papules on the seborrheic areas of the trunk, scalp, forehead and flexures, and the clinical picture is worsened by heat, sun exposure, perspiration and mechanical trauma. Histopathology observed loss of epithelial adhesion and abnormal keratinization. About 10% of cases present in the localized form of the disease. We report a case of segmental Darier's Disease Type I and discuss the main characteristics of this condition.
authors: Universidade do Estado do Rio de Janeiro, Guarulhos, SP, BR.
authors: Paula Mota
authors: PM
authors: Medeiros
authors: Universidade do Estado do Rio de Janeiro, Guarulhos, SP, BR.
authors: Natália Ribeiro de Magalhães
authors: NR
authors: Alves
authors: Universidade do Estado do Rio de Janeiro, Guarulhos, SP, BR.
authors: Jeniffer Muñoz
authors: JM
authors: Trujillo
authors: Universidade do Estado do Rio de Janeiro, Guarulhos, SP, BR.
authors: Cássia Camarinha da
authors: CC
authors: Silva
authors: Universidade do Estado do Rio de Janeiro, Guarulhos, SP, BR.
authors: Paula Carolina Pessanha de
authors: PC
authors: Faria
authors: Universidade do Estado do Rio de Janeiro, Guarulhos, SP, BR.
authors: Roberto Souto da
authors: RS
authors: Silva
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D007644:Darier Disease / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D005533:Foot Dermatoses / Q000473:pathology; D006801:Humans; D007868:Leg Dermatoses / Q000473:pathology; D016896:Treatment Outcome