title: Best Practices in Alemtuzumab Administration: Practical Recommendations for Infusion in Patients With Multiple Sclerosis.
abstract: With the growing complexity of multiple sclerosis (MS) care, nursing professionals have increasing responsibility in managing clinical disease and treatment. Nursing professionals and other health care providers play important roles in educating patients about disease-modifying therapy options, the course of therapy, and managing potential adverse effects. A panel of nursing and MS experts was convened and used a modified Delphi method to reach consensus on best-practice recommendations for alemtuzumab infusion in MS patients. This valuable clinical resource provides a practical guide for clinicians to optimize patient education and implement strategies for infusion-associated reaction prophylaxis and management when administering alemtuzumab.
authors: London Health Sciences Centre, London, Ontario, Canada (Ms McEwan); Multiple Sclerosis Center, Wayne State University School of Medicine, Detroit, Michigan (Ms Caon); Neuroscience Center, Allegheny General Hospital, Pittsburgh, Pennsylvania (Ms Chieffe); Central Texas Neurology Consultants, Round Rock, Texas (Dr Mayer); Multiple Sclerosis Comprehensive Care Center, Baylor College of Medicine, Houston, Texas (Ms Saldana-King); Genzyme, Cambridge, Massachusetts (Dr Miller). Lynn McEwan, MScN, NP, MSCN, CNNc, is a nurse practitioner at the Multiple Sclerosis Clinic of the London Health Sciences Centre in London, Ontario, Canada. She has specialized in the care of patients with multiple sclerosis for 25 years and is certified in multiple sclerosis and neuroscience nursing. Ms. McEwan has published and lectured on a variety of multiple sclerosis-related topics from disease management to nursing. She is a past president of the Multiple Sclerosis Nursing International Certification Board. Christina Caon, MSN, RN, NP-C, is a nurse practitioner and the assistant director of clinical research at the Multiple Sclerosis Center at Wayne State University. She has been involved with clinical trial research and numerous investigator-initiated trials for more than 14 years. She also has been an invited speaker and presented data at numerous national and international meetings focused on multiple sclerosis. Carol Chieffe, MSCN, RN, CCRC, is a clinical nurse at Allegheny General Hospital's Multiple Sclerosis Treatment Center, where she was instrumental in the development of the infusion center. She is active with the National Multiple Sclerosis Society as a health care advocate for government affairs on the state and federal levels. Lori Mayer, DNP, MSN, RN, the director of medical research services for the Multiple Sclerosis Clinic of Central Texas, manages multiple sclerosis clinical research programs, patient-centered education, and clinical care. In addition, she writes posters an
authors: Lynn
authors: L
authors: McEwan
authors: Christina
authors: C
authors: Caon
authors: Carol
authors: C
authors: Chieffe
authors: Lori
authors: L
authors: Mayer
authors: Toni
authors: T
authors: Saldana-King
authors: Colleen E
authors: CE
authors: Miller
mesh_terms: D000328:Adult; D000074323:Alemtuzumab; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D003697:Delphi Technique; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral / Q000592:standards*; D008297:Male; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000451:nursing*; D017410:Practice Guidelines as Topic; D014481:United States
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000074323:Alemtuzumab