title: Facial rejuvenation starts in the midface: three-dimensional volumetric facial rejuvenation has beneficial effects on nontreated neighboring esthetic units.
abstract: Facial aging is a major indication for minimal invasive esthetic procedures. Dermal fillers are a cornerstone in the approach for facial sculpturing. But where to start? Our concept is midfacial volume restoration in first place. This will result in a healthy and youthful appearance creating a facial V-shape. But midfacial filler injection does not only improve the malar area. It has also beneficial effects on neighboring esthetic units. We report on such improvements in periocular and nasolabial region, upper lips and perioral tissue, and the jaw line and discuss anatomical background. We hypothesize that midfacial deep filler injections also may activate subdermal white adipose tissue stem cells contributing to longer lasting rejuvenation.
authors: Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
authors: Uwe
authors: U
authors: Wollina
mesh_terms: D003357:Cosmetic Techniques; D000067548:Dermal Fillers / Q000008:administration & dosage*; D004954:Esthetics; D005145:Face; D006801:Humans; D007267:Injections / Q000379:methods; D012060:Rejuvenation; D015595:Skin Aging
chemical_list: D000067548:Dermal Fillers
keywords: adipose tissue; calcium hydroxylapatite; dermal fillers; facial aging; hyaluronic acid; midfacial sculpturing