title: Sjögren Syndrome Complicated by Mucosa-Associated Lymphoid Tissue Lymphoma and Lymphocytic Interstitial Pneumonia.
abstract: Sjögren syndrome (SS) is an autoimmune disease with exocrine glands dysfunction and multiorgan involvement. It is associated with increased risk of lymphoproliferative disorders, especially B-cell marginal zone lymphoma. While the role of F-18 Fluorodeoxyglucose position emission tomography/computed tomography (F-18 FDG PET/CT) for evaluation of lymphoma has been established, its use in patients with a chronic history of SS to evaluate for possible lymphoproliferative disorders or multiorgan involvement is limited. We present a case of chronic SS in which F-18 FDG PET/CT demonstrated FDG avid intraparotid and cervical lymph nodes pathologically proven to be mucosa-associated lymphoid tissue lymphoma. In addition, the patient had bibasilar cystic changes consistent with lymphocytic interstitial pneumonia.
authors: Saint Louis Univeristy , Saint Louis, MO , USA.
authors: Fatma
authors: F
authors: Ahmed
authors: Saint Louis Univeristy , Saint Louis, MO , USA.
authors: Osama
authors: O
authors: Raslan
authors: Saint Louis Univeristy , Saint Louis, MO , USA.
authors: Razi
authors: R
authors: Muzaffar
authors: Saint Louis Univeristy , Saint Louis, MO , USA.
authors: Nadeem
authors: N
authors: Parkar
authors: Saint Louis Univeristy , Saint Louis, MO , USA.
authors: Nitin
authors: N
authors: Marwaha
authors: Saint Louis Univeristy , Saint Louis, MO , USA.
authors: Medhat M
authors: MM
authors: Osman
keywords: FDG PET/CT; FDG avid; LIP; MALT lymphoma; Sjögren syndrome