title: Delayed reactivation of chronic infantile neurologic, cutaneous, articular syndrome (CINCA) in a patient with somatic mosaicism of CIAS1/NLRP3 gene after withdrawal of anti-IL-1 beta therapy.
authors: Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
authors: Giulia
authors: G
authors: Paloni
authors: Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
authors: Serena
authors: S
authors: Pastore
authors: Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
authors: Alberto
authors: A
authors: Tommasini
authors: University of Trieste, Trieste, Italy.
authors: Loredana
authors: L
authors: Lepore
authors: Institute for Maternal and Child Health, IRCCS Burlo Garofolo, and University of Trieste, Trieste, Italy.
authors: Andrea
authors: A
authors: Taddio
mesh_terms: D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D061067:Antibodies, Monoclonal, Humanized; D002352:Carrier Proteins / Q000235:genetics*; D056587:Cryopyrin-Associated Periodic Syndromes / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics / Q000276:immunology; D004334:Drug Administration Schedule; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D053590:Interleukin 1 Receptor Antagonist Protein / Q000008:administration & dosage*; D053583:Interleukin-1beta / Q000037:antagonists & inhibitors* / Q000276:immunology; D009030:Mosaicism; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D010641:Phenotype; D012008:Recurrence; D012074:Remission Induction; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D002352:Carrier Proteins; C508585:IL1B protein, human; D007166:Immunosuppressive Agents; D053590:Interleukin 1 Receptor Antagonist Protein; D053583:Interleukin-1beta; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C453881:NLRP3 protein, human; C541220:canakinumab