title: Catalytic Asymmetric Oxidative α-C-H N,O-Ketalization of Ketones by Chiral Primary Amine.
abstract: A highly enantioselective primary amine catalyzed α,α-bis-functionalization of β-ketocarbonyls and cyclohexanones is described. This transformation employs N-hydroxycarbamates as both nitrogen and oxygen sources under aerobic oxidative conditions to furnish chiral N,O-ketals with high yields and enantioselectivities.
authors: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing, 100190, China.
authors: Changming
authors: C
authors: Xu
authors: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing, 100190, China.|Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300071, China.
authors: Long
authors: L
authors: Zhang
authors: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences , Beijing, 100190, China.|Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300071, China.
authors: Sanzhong
authors: S
authors: Luo