title: Grass pollen sublingual immunotherapy and paediatric allergic rhinitis: A patient-oriented decision.
abstract: Guidelines and systematic review report that allergen immunotherapy (AIT) is, in general, effective in the treatment of allergic rhinitis. However, experts suggest not generalising the results of different clinical studies: for example, it would not be advisable to translate the results found in an adult population to a paediatric population or the results on the efficacy of AIT against a specific allergen to the AIT against a different allergen. Moreover, according to Evidence Based Medicine (EBM), clinical decisions are individualised and should derive from the "integration of best research evidence with clinical expertise and patient values". Taking into account the high specificity of the AIT and EBM principles, we tried to answer the question on how advisable it is to prescribe the AIT for the management of grass allergic rhinitis in children. To do this, we revised the scientific literature in order to solve a specific case scenario.
authors: Department of Pediatrics, Agostino Gemelli Hospital, Catholic University of Sacred Heart, Rome, Italy. Electronic address: smicelisopo@rm.unicatt.it.
authors: Stefano
authors: S
authors: Miceli Sopo
authors: Department of Pediatrics, Agostino Gemelli Hospital, Catholic University of Sacred Heart, Rome, Italy.
authors: Andrea
authors: A
authors: Battista
authors: Department of Pediatrics, Agostino Gemelli Hospital, Catholic University of Sacred Heart, Rome, Italy.
authors: Monica
authors: M
authors: Greco
authors: Department of Pediatrics, Agostino Gemelli Hospital, Catholic University of Sacred Heart, Rome, Italy.
authors: Serena
authors: S
authors: Monaco
mesh_terms: D000286:Administration, Sublingual; D002648:Child; D000066491:Clinical Decision-Making; D019317:Evidence-Based Medicine / Q000379:methods; D006801:Humans; D008297:Male; D000068656:Mometasone Furoate / Q000008:administration & dosage / Q000627:therapeutic use; D006109:Poaceae / Q000276:immunology*; D011058:Pollen / Q000276:immunology*; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy / Q000628:therapy*; D013147:Spirometry; D063729:Sublingual Immunotherapy / Q000379:methods*
chemical_list: D000068656:Mometasone Furoate
keywords: Allergic rhinitis; Children; Evidence Based Medicine; Sublingual immunotherapy