title: Mucocutaneous Inflammatory Pseudotumours in Simultaneous Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis Infection in a Cat.
abstract: Mycobacterial spindle cell 'pseudotumour' has been described only once in cats. This unique proliferation of spindle-shaped histiocytes containing Mycobacterium avium is associated with extensive subcutaneous lesions. We report mycobacterial pseudotumour with invasion of muscular and subcutaneous tissues in a 1-year-old female domestic longhair cat. Lesions involved the facial muscles and nasal cavity, making surgical excision impossible. Necropsy examination revealed additional nodules in the subcutis and muscles of the trunk and submandibular lymph nodes. Genotyping of organisms within these lesions revealed simultaneous infection with Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis. The microscopical appearance of the granulomas was identical, regardless of the strain of bacterium or anatomical location.
authors: Department of Veterinary Pathology, Veterinary Faculty, University of Zagreb, Ulica Vjekoslava Heinzela 55, Zagreb, Croatia. Electronic address: abeck@vef.hr.
authors: A
authors: A
authors: Beck
authors: Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Zagreb, Savska cesta 143, Zagreb, Croatia.
authors: S
authors: S
authors: Špičić
authors: Veterinary Practice Pharos, Stari Grad, Island of Hvar, Croatia.
authors: M
authors: M
authors: Butorović-Dujmović
authors: Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Zagreb, Savska cesta 143, Zagreb, Croatia.
authors: I
authors: I
authors: Račić
authors: Department of Veterinary Pathology, Veterinary Faculty, University of Zagreb, Ulica Vjekoslava Heinzela 55, Zagreb, Croatia.
authors: D
authors: D
authors: Huber
authors: Department of Veterinary Pathology, Veterinary Faculty, University of Zagreb, Ulica Vjekoslava Heinzela 55, Zagreb, Croatia.
authors: A
authors: A
authors: Gudan Kurilj
authors: Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Zagreb, Savska cesta 143, Zagreb, Croatia.
authors: R
authors: R
authors: Beck
authors: Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Zagreb, Savska cesta 143, Zagreb, Croatia.
authors: Ž
authors: Ž
authors: Cvetnić
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000382:microbiology* / Q000473:pathology*; D002415:Cats; D005260:Female; D006104:Granuloma, Plasma Cell / Q000382:microbiology*; D009162:Mycobacterium avium; D014376:Tuberculosis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*
keywords: Mycobacterium avium subspecies avium; Mycobacterium avium subspecies hominissuis; cat; inflammatory pseudotumour