title: [Optimization of extraction technology of compatibility of couplet medicines Epimedium brevicornu and Ligusticum chuanxiong by orthogonal design].
abstract: The study was using the orthogonal test and making the extraction rates of icariin, ferulic acid, epimedin A, epimedin B, epimedin C, baohuoside I and ligustilide determinated by HPLC multiwavelength switch, gradient elution and multi-index comprehensive weighted scoring method (weight coefficient was 0.47: 0.16: 0.07: 0.07: 0.08: 0.06: 0.09) as evaluation index, combine with SPSS 16.0 software to optimizing the best extraction. It was Yinpian soak 1 h, 12 times more than the volumn of 50% ethanol solution, by heating reflux extraction for 60 min. The compliance test indicates that the optimized compatibility extraction technology is stable and practical, and it has provided an experimental basis for compound preparation technology research of Epimedium brevicornu and Ligusticum chuanxiong.
authors: Hong
authors: H
authors: Ren
authors: Xuan
authors: X
authors: Wang
authors: Lin
authors: L
authors: Zhang
authors: Jing
authors: J
authors: Xing
authors: Ru-wei
authors: RW
authors: Wang
authors: Hua
authors: H
authors: Yin
mesh_terms: D005591:Chemical Fractionation / Q000379:methods*; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D034181:Epimedium / Q000737:chemistry*; D030004:Ligusticum / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal