title: [Enophthalmos as a first sign of breast cancer].
abstract: BACKGROUND
  Metastasis of breast carcinoma to the orbit is characterized by symptoms of altered appearance and double vision. A combination of enophthalmos, ptosis and impairment of eye movements is typical. Sometimes these symptoms are the first manifestation of breast carcinoma.
  
  
  METHODS
  Two female patients, aged 66 and 52, presented with enophthalmos. Both had recently undergone mammography with no abnormalities being observed. CT scans of these patients disclosed an intra-orbital, space-occupying process. Histological examination of biopsies from the abnormal tissue revealed that both patients had metastatic breast carcinoma.
  
  
  CONCLUSIONS
  In a female patient with non-traumatic enophthalmos, metastasis of breast carcinoma must be ruled out and reliance may not be placed on a mammogram revealing no abnormalities.
authors: Academisch Medisch Centrum, afd. Oogheelkunde, Amsterdam.
authors: Maarten P
authors: MP
authors: Mourits
authors: Peerooz
authors: P
authors: Saeed
authors: Roel J H M
authors: RJ
authors: Kloos
mesh_terms: D000368:Aged; D001706:Biopsy; D001943:Breast Neoplasms / Q000175:diagnosis*; D018275:Carcinoma, Lobular / Q000175:diagnosis*; D004172:Diplopia; D015841:Enophthalmos / Q000209:etiology*; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009918:Orbital Neoplasms / Q000150:complications / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed