title: Endoscopic Bypass Using Endobarrier Devices: Efficacy in Treating Obesity and Metabolic Syndrome.
abstract: Obesity is a rapidly growing pandemic. Scope of pharmacotherapy and bariatric surgery in managing obesity is ever rising. The role of minimally invasive techniques to achieve preoperative weight loss and improve postbariatric surgery outcomes is an area of new interest. The initial experience with endobarrier devices in achieving weight loss among obese subjects has shown promising results. In addition, the impact of these interventions on comorbidities commonly associated with obesity like diabetes mellitus type 2 and hyperlipidemia has further expanded their potential for use in future. In this review article, we have summarized case report, prospective single and multicenter studies, and randomized-controlled trials describing the use of endobarrier devices. Indications, techniques, outcomes, limitations, and complications reported are discussed.
authors: *Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA †Division of Gastroenterology, Hepatology and Nutrition, University of Texas Health Science Center at Houston, Houston, TX.
authors: Deepanshu
authors: D
authors: Jain
authors: Shashideep
authors: S
authors: Singhal
mesh_terms: D050110:Bariatric Surgery / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D004386:Duodenum / Q000601:surgery; D016099:Endoscopy, Gastrointestinal / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D007583:Jejunum / Q000601:surgery; D009767:Obesity, Morbid / Q000601:surgery*; D011300:Preoperative Care / Q000295:instrumentation* / Q000379:methods; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D015431:Weight Loss