title: Postoperative Psychiatric Complications in Living Liver Donors.
abstract: BACKGROUND
  To understand the impact of psychologic variables on donor quality of life, we studied long-term data on postoperative psychiatric complications in living liver donors. This study is a focused psychological investigation of diagnoses, treatments, and long-term clinical courses of living liver donors with psychiatric complications.
  
  
  METHODS
  Of the 142 donors who underwent live-donor liver transplantation at Nagoya University Hospital between April 2004 and July 2014, we investigated those without a history of mental illness who had developed such illness after transplantation and required psychiatric treatment.
  
  
  RESULTS
  A total of 6 (4.2%) donors developed the following psychiatric complications after transplantation: major depressive disorder (n = 2), panic disorder (n = 2), conversion disorder (n = 1), and substance use disorder (n = 1). Concerning psychiatric treatment, all donors received antianxiety drugs, 3 took antidepressants, and supportive psychiatric therapy was concomitantly provided to all subjects. The average treatment period was 53.3 months. Regarding subject outcomes, 3 donors achieved remission, and the other 3 continued treatment. All subjects showed improvement in Global Assessment of Functioning Scale.
  
  
  CONCLUSIONS
  It is important to accurately diagnose postoperative psychiatric complications and provide long-term treatment in close coordination with transplant surgeons.
authors: Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: kimurahi@med.nagoya-u.ac.jp.
authors: H
authors: H
authors: Kimura
authors: Transplantation Surgery, Nagoya University Hospital, Nagoya, Japan.
authors: Y
authors: Y
authors: Onishi
authors: Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors: S
authors: S
authors: Sunada
authors: Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors: S
authors: S
authors: Kishi
authors: Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors: N
authors: N
authors: Suzuki
authors: Transplantation Surgery, Nagoya University Hospital, Nagoya, Japan.
authors: C
authors: C
authors: Tsuboi
authors: Transplantation Surgery, Nagoya University Hospital, Nagoya, Japan.
authors: N
authors: N
authors: Yamaguchi
authors: Transplantation Surgery, Nagoya University Hospital, Nagoya, Japan.
authors: H
authors: H
authors: Imai
authors: Transplantation Surgery, Nagoya University Hospital, Nagoya, Japan.
authors: H
authors: H
authors: Kamei
authors: Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors: H
authors: H
authors: Fujisiro
authors: Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors: T
authors: T
authors: Okada
authors: Department of Gastroenterology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors: M
authors: M
authors: Ishigami
authors: Transplantation Surgery, Nagoya University Hospital, Nagoya, Japan.
authors: Y
authors: Y
authors: Ogura
authors: Sing-Kobe Liver Transplant Centre, Mount Elizabeth Novena Hospital, Singapore.
authors: T
authors: T
authors: Kiuchi
authors: Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.
authors: N
authors: N
authors: Ozaki
mesh_terms: D000328:Adult; D003865:Major Depressive Disorder / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006498:Hepatectomy / Q000523:psychology*; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology*; D011788:Quality of Life; D055815:Young Adult