title: Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy.
abstract: Treatment of ischemic cardiomyopathy caused by myocardial infarction (MI) using mesenchymal stem cell (MSC) transplantation is a widely researched field, with promising clinical application. However, the low survival rate of transplanted cells has a severe impact on treatment outcome. Currently, research is focused on investigating the strategy of combining genetic engineering, tissue engineering materials, and drug/hypoxia preconditioning to improve ischemic cardiomyopathy treatment outcome using MSC transplantation treatment (MSCTT). This review discusses the application and progress of these techniques.
authors: Department of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
authors: Ping
authors: P
authors: Hua
authors: Department of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
authors: Jian-Yang
authors: JY
authors: Liu
authors: Department of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
authors: Jun
authors: J
authors: Tao
authors: Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK.
authors: Song-Ran
authors: SR
authors: Yang
mesh_terms: D000818:Animals; D009202:Cardiomyopathies / Q000209:etiology* / Q000628:therapy*; D005818:Genetic Engineering; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D017202:Myocardial Ischemia / Q000150:complications* / Q000628:therapy; D023822:Tissue Engineering