title: A Long-Distance Chromatin Affair.
abstract: Changes in transcription factor binding sequences result in correlated changes in chromatin composition locally and at sites hundreds of kilobases away. New studies demonstrate that this concordance is mediated via spatial chromatin interactions that constitute regulatory modules of the human genome.
authors: Hubrecht Institute-KNAW and University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands.
authors: Annette
authors: A
authors: Denker
authors: Hubrecht Institute-KNAW and University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands. Electronic address: w.delaat@hubrecht.eu.
authors: Wouter
authors: W
authors: de Laat
mesh_terms: D002843:Chromatin / Q000737:chemistry* / Q000378:metabolism*; D002877:Chromosomes, Human / Q000378:metabolism*; D005260:Female; D005786:Gene Expression Regulation; D014644:Genetic Variation; D015894:Genome, Human; D016045:Human Genome Project; D006801:Humans; D008297:Male
chemical_list: D002843:Chromatin