title: Expression of CD90 decreases with progression of synovial chondromatosis in the temporomandibular joint.
abstract: OBJECTIVE
  The aim of the present study was to investigate the factors that contribute to the progression of synovial chondromatosis in the temporomandibular joint (TMJ).
  
  
  METHODS
  The authors investigated the expression of CD105 and CD90 in specimens from 17 patients with synovial chondromatosis in the TMJ, using immunohistochemical staining, and expression of CD105 and CD90 in cartilaginous nodules was scored semiquantitatively.
  
  
  RESULTS
  The expression of CD105 and CD90 was found in almost all the cases. In particular, the expression of CD90 in cartilaginous nodules significantly decreased with the progression of synovial chondromatosis.
  
  
  CONCLUSIONS
  The factors that determine progression of synovial chondromatosis are not fully understood. The results of this study suggest that CD90 may play an important role in the progression of synovial chondromatosis in the TMJ.
authors: a Department of Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Japan.
authors: So
authors: S
authors: Wake
authors: a Department of Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Japan.
authors: Hiroyuki
authors: H
authors: Yoshitake
authors: b Department of Oral Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Japan.
authors: Kou
authors: K
authors: Kayamori
authors: c Department of Diagnostic Oral Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Japan.
authors: Toshiyuki
authors: T
authors: Izumo
authors: a Department of Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University , Japan.
authors: Kiyoshi
authors: K
authors: Harada
mesh_terms: D000328:Adult; D000368:Aged; D015838:Chondromatosis, Synovial / Q000378:metabolism* / Q000473:pathology; D018450:Disease Progression; D000071063:Endoglin / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013704:Temporomandibular Joint / Q000378:metabolism / Q000473:pathology; D013705:Temporomandibular Joint Disorders / Q000378:metabolism* / Q000473:pathology; D018800:Thy-1 Antigens / Q000378:metabolism*
chemical_list: D000071063:Endoglin; D018800:Thy-1 Antigens
keywords: CD105; CD90; Chondrocyte; Immunohistochemical staining; Synovial chondromatosis; Temporomandibular joint