title: Clinical study replicability and the pursuit of excellence.
abstract: Comparisons of processes of care are common in critical care research. Often, these processes are neither explicit nor replicable and this can result in seemingly irreconcilable results. Here, we briefly review the article by Taniguchi and colleagues, who studied liberation from mechanical ventilation by using either a computerized weaning protocol or one driven by respiratory therapists. We discuss the implications of explicit protocols increasing replicability in clinical research.
authors: Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, 5121 S. Cottonwood Street, Murray, UT, 84107, USA. michael.lanspa@imail.org.|Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, 26 North 1900 East, Salt Lake City, UT, 84132, USA. michael.lanspa@imail.org.
authors: Michael J
authors: MJ
authors: Lanspa
authors: Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, 5121 S. Cottonwood Street, Murray, UT, 84107, USA.|Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, 26 North 1900 East, Salt Lake City, UT, 84132, USA.|Division of Pediatric Critical Care, Department of Pediatrics, University of Utah, 295 Chipeta Way, Salt Lake City, UT, 84108, USA.
authors: Eliotte L
authors: EL
authors: Hirshberg
authors: Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, 5121 S. Cottonwood Street, Murray, UT, 84107, USA.|Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, 26 North 1900 East, Salt Lake City, UT, 84132, USA.
authors: Russell R
authors: RR
authors: Miller
authors: Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, 5121 S. Cottonwood Street, Murray, UT, 84107, USA.|Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah, 26 North 1900 East, Salt Lake City, UT, 84132, USA.
authors: Alan H
authors: AH
authors: Morris
mesh_terms: D035843:Biomedical Research / Q000379:methods / Q000592:standards; D002985:Clinical Protocols / Q000592:standards; D003422:Critical Care / Q000379:methods / Q000592:standards; D003658:Decision Making, Computer-Assisted; D006801:Humans; D015203:Reproducibility of Results; D015300:Ventilator Weaning / Q000379:methods