title: Genetics of Refraction and Myopia.
abstract: Both genetic and environmental factors play roles in the development of refractive errors. Identification of genes involved in refractive errors may help in elucidating the underlying molecular mechanism related to both genetic defects and environmental pressure. Recent development of techniques for genome wide analysis provides unique opportunity in dissecting the genetic basis related to refractive errors. This chapter tries to give a brief overview on the recent progress of genetic study of refractive errors, especially myopia.
authors: State Key Lab of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, PR China. Electronic address: zhangqji@mail.sysu.edu.cn.
authors: Qingjiong
authors: Q
authors: Zhang
mesh_terms: D056426:Genetic Loci; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D006956:Hyperopia / Q000235:genetics; D009216:Myopia / Q000235:genetics* / Q000503:physiopathology*; D012029:Refraction, Ocular / Q000235:genetics*
keywords: Gene; Genetics; Linkage mapping; Mutations; Myopia; Refractive error; Sequencing; Variants