title: Malignant fungal infection of the cavernous sinus: case report.
abstract: Intracranial spread of fungal infection is a life-threatening condition that usually affects immunocompromised patients. Here the authors present a case of biopsy-proven Aspergillus fumigatus infection of the paranasal sinuses in an immunocompetent patient with documented spread to the orbit, cavernous sinus, and petrous apex despite medical antifungal treatment. As a life-saving treatment, cavernous sinus resection with external carotid artery-middle cerebral artery bypass was performed. The authors discuss the literature regarding the intracranial spread of paranasal sinus fungal infections in immunocompetent patients and management strategies.
authors: Department of Neurosurgery; and.
authors: Jayson A
authors: JA
authors: Neil
authors: Department of Surgery, Division of Otolaryngology, University of Utah School of Medicine, Salt Lake City, Utah.
authors: Richard R
authors: RR
authors: Orlandi
authors: Department of Neurosurgery; and.
authors: William T
authors: WT
authors: Couldwell
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001232:Aspergillus fumigatus; D002426:Cavernous Sinus; D006801:Humans; D008297:Male; D020953:Neuroaspergillosis / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy
chemical_list: D000935:Antifungal Agents
keywords: Aspergillus fumigatus; CCA = common carotid artery; ECA = external carotid artery; ECA-MCA bypass; ICA = internal carotid artery; MCA = middle cerebral artery; cavernous sinus infection; cavernous sinus resection; paranasal fungal infection