title: Facial, vocal and cross-modal emotion processing in early-onset schizophrenia spectrum disorders.
abstract: Recognition of emotional expressions plays an essential role in children's healthy development. Anomalies in these skills may result in empathy deficits, social interaction difficulties and premorbid emotional problems in children and adolescents with schizophrenia. Twenty-six subjects with early onset schizophrenia spectrum (EOSS) disorders and twenty-eight matched healthy controls (HC) were instructed to identify five basic emotions and a neutral expression. The assessment entailed presenting visual, auditory and congruent cross-modal stimuli. Using a generalized linear mixed model, we found no significant association for handedness, age or gender. However, significant associations emerged for emotion type, perception modality, and group. EOSS patients performed worse than HC in uni- and cross-modal emotional tasks with a specific negative emotion processing impairment pattern. There was no relationship between emotion identification scores and positive or negative symptoms, self-reported empathy traits or a positive history of developmental disorders. However, we found a significant association between emotional identification scores and nonverbal communication impairments. We conclude that cumulative dysfunctions in both nonverbal communication and emotion processing contribute to the social vulnerability and morbidity found in youths who display EOSS disorder.
authors: Département de Psychiatrie de l'Enfant et l'Adolescent, APHP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France; Institut des Systèmes Intelligents et Robotique, ISIR, CNRS UMR 7222, Université Pierre et Marie Curie, Paris, France. Electronic address: giannitelli.m@gmail.com.
authors: Marianna
authors: M
authors: Giannitelli
authors: Département de Psychiatrie de l'Enfant et l'Adolescent, APHP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France; Institut des Systèmes Intelligents et Robotique, ISIR, CNRS UMR 7222, Université Pierre et Marie Curie, Paris, France.
authors: Jean
authors: J
authors: Xavier
authors: Service de Pédopsychiatrie, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Bruxelles, Belgium.
authors: Anne
authors: A
authors: François
authors: Département de Psychiatrie de l'Enfant et l'Adolescent, APHP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors: Nicolas
authors: N
authors: Bodeau
authors: Département de Psychiatrie de l'Enfant et l'Adolescent, APHP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France; Department of Psychiatry, Stanford University, Stanford, CA, USA.
authors: Claudine
authors: C
authors: Laurent
authors: Département de Psychiatrie de l'Enfant et l'Adolescent, APHP, Groupe Hospitalier Pitié-Salpêtrière, Paris, France; Institut des Systèmes Intelligents et Robotique, ISIR, CNRS UMR 7222, Université Pierre et Marie Curie, Paris, France.
authors: David
authors: D
authors: Cohen
authors: Institut des Systèmes Intelligents et Robotique, ISIR, CNRS UMR 7222, Université Pierre et Marie Curie, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Institut de Psychologie, Boulogne-Billancourt, France.
authors: Laurence
authors: L
authors: Chaby
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D002648:Child; D004644:Emotions; D005149:Facial Expression; D000066499:Facial Recognition; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D011569:Psychiatric Status Rating Scales; D011581:Psychological Tests; D011618:Psychotic Disorders / Q000188:drug therapy / Q000523:psychology*; D021641:Recognition, Psychology; D012559:Schizophrenia / Q000188:drug therapy; D012565:Schizophrenic Psychology; D012938:Social Perception; D013067:Speech Perception
keywords: Cross-modal integration; Early and very early onset schizophrenia; Facial emotion; Vocal emotion