title: Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases.
abstract: This chapter examines the use of proteomics in understanding pathogenesis and identifying possible biomarkers in a range of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and prion diseases. We have attempted to look at the neuroproteomic approach from a biomarker discovery point of view. Novel biomarkers can pave the way for new therapeutic targets and lead us to a better understanding of the pathogenesis involved in the neurodegenerative diseases.
authors: Centre for Infection, Immunity and Disease Mechanisms, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom; Centre for Biotechnology and Bioinformatics, School of Life Sciences, Jawaharlal Nehru Institute for Advanced Studies, Secunderabad, Telangana, India.
authors: Annapurna
authors: A
authors: Nayak
authors: Centre for Infection, Immunity and Disease Mechanisms, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
authors: Gregory
authors: G
authors: Salt
authors: Center for Cellular and Molecular Biology, Hyderabad, Telangana, India.
authors: Sunil K
authors: SK
authors: Verma
authors: Centre for Infection, Immunity and Disease Mechanisms, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom. Electronic address: uday.kishore@brunel.ac.uk.
authors: Uday
authors: U
authors: Kishore
mesh_terms: D015415:Biomarkers / Q000378:metabolism*; D006801:Humans; D019636:Neurodegenerative Diseases / Q000175:diagnosis* / Q000378:metabolism*; D040901:Proteomics / Q000379:methods*
chemical_list: D015415:Biomarkers
keywords: Biomarker; Neurodegeneration; Neuroinflammation; Proteomic