title: Robotic nerve-sparing radical hysterectomy for locally advanced cervical cancer after neoadjuvant chemotherapy.
abstract: OBJECTIVE
  To evaluate the feasibility and safety of robotic nerve-sparing radical hysterectomy for locally advanced cervical cancer (LACC).
  
  
  METHODS
  In a retrospective study, data were analyzed for patients treated for cervical cancer at a center in Beijing, China, between December 2011 and September 2013. Patients were subdivided into those with early-stage disease (FIGO stage IA2-IB1) who were treated by robotic surgery (group 1), and those with LACC (stage IB2-IIB) who were treated by robotic surgery after neoadjuvant chemotherapy (NACT; group 2). Therapeutic outcomes and complications were compared.
  
  
  RESULTS
  Group 1 included 32 patients and group 2 included 22 patients. Two patients in group 2 did not respond to NACT and did not undergo surgery. The operative outcomes and incidences of complications did not differ significantly between the two groups (P>0.05 for all). There were no differences in nodal yield, lengths of parametrium removed, or vaginal cuff length (P>0.05 for all). During a mean follow-up of 26months, no patient experienced recurrence.
  
  
  CONCLUSIONS
  Robotic nerve-sparing radical hysterectomy was found to be feasible and safe for LACC after NACT. A larger case series with longer follow-up data is needed to justify its widespread application.
authors: Department of Obstetrics and Gynecology, PLA General Hospital, Beijing, China.
authors: Zhongyu
authors: Z
authors: Liu
authors: Department of Obstetrics and Gynecology, Hainan Branch of PLA General Hospital, Sanya, China.
authors: Xiuli
authors: X
authors: Li
authors: Department of Obstetrics and Gynecology, PLA General Hospital, Beijing, China.
authors: Weiping
authors: W
authors: Li
authors: Department of Obstetrics and Gynecology, PLA General Hospital, Beijing, China.
authors: Yizhuo
authors: Y
authors: Yang
authors: Department of Ophthalmology, PLA General Hospital, Beijing, China.
authors: Ye
authors: Y
authors: Tao
authors: Department of Obstetrics and Gynecology, PLA General Hospital, Beijing, China. Electronic address: yqyao301hp@163.com.
authors: Yuanqing
authors: Y
authors: Yao
mesh_terms: D000328:Adult; D000368:Aged; D017024:Chemotherapy, Adjuvant; D002681:China; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D059351:Organ Sparing Treatments / Q000379:methods; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D065287:Robotic Surgical Procedures / Q000379:methods*; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*
keywords: Cervical cancer; Neoadjuvant chemotherapy; Nerve-sparing; Pelvic lymphadenectomy; Radical hysterectomy; Robotic surgery