title: Probing into the Supramolecular Driving Force of an Amphiphilic β-Cyclodextrin Dimer in Various Solvents: Host-Guest Recognition or Hydrophilic-Hydrophobic Interaction?
abstract: Tuning of the morphology and size of supramolecular self-assemblies is of theoretical and practical significance. To date, supramolecular driving forces in different solvents remain unclear. In this study, we first synthesized an amphiphilic β-cyclodextrin (β-CD) dimer that consists of one hydrophobic ibuprofen (Ibu) and two hydrophilic β-CD moieties (i.e., Ibu-CD2). Ibu-CD2 possesses double supramolecular driving forces, namely, the host-guest recognition and hydrophilic-hydrophobic interaction. The host-guest interaction of Ibu-CD2 induced the formation of branched supramolecular polymers (SPs) in pure water, whereas the hydrophilic-hydrophobic interaction generated spherical or irregular micelles in water/organic mixtures. The SP size increased with the increase in Ibu-CD2 concentration in pure water. By contrast, the size of micelles decreased with the increase in volume ratio of water in mixtures.
authors: Xi'an Mordern Chemistry Research Institute , Xi'an, 710065, P. R. China.
authors: Yang
authors: Y
authors: Bai
authors: The Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University , Xi'an, 710072, P. R. China.
authors: Xiao-dong
authors: XD
authors: Fan
authors: The Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University , Xi'an, 710072, P. R. China.
authors: Hao
authors: H
authors: Yao
authors: The Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University , Xi'an, 710072, P. R. China.
authors: Zhen
authors: Z
authors: Yang
authors: The Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University , Xi'an, 710072, P. R. China.
authors: Ting-ting
authors: TT
authors: Liu
authors: The Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University , Xi'an, 710072, P. R. China.
authors: Hai-tao
authors: HT
authors: Zhang
authors: The Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University , Xi'an, 710072, P. R. China.
authors: Wan-bin
authors: WB
authors: Zhang
authors: The Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University , Xi'an, 710072, P. R. China.
authors: Wei
authors: W
authors: Tian