title: Identification and reduction of image artifacts in non-contrast-enhanced velocity-selective peripheral angiography at 3T.
abstract: To identify and reduce image artifacts in non-contrast-enhanced velocity-selective (VS) magnetization-prepared peripheral MR angiography (MRA) at 3T.
  
  
  
  To avoid signal loss in the arteries, double and quadruple refocused VS excitation pulse sequences were designed that were robust to a wide range of B0 and B1 offset. To suppress stripe artifact and background signal variation, we successively applied two VS preparations with excitation profiles shifted by half the period of the stripes. VS-MRA using single, double, and quadruple refocused VS preparations was tested in healthy subjects and a patient.
  
  
  
  In the regions of large B0 and B1 offsets, arterial signal loss was yielded by single refocused VS preparation, but was avoided with double or quadruple refocused preparations. Compared with single VS preparation, the two consecutive preparations with shifted excitation profiles substantially reduced the stripe artifact and background signal variation, as demonstrated by increased mean and decreased standard deviation of relative contrast-to-noise ratio. The proposed VS-MRA identified multilevel disease in the femoral arteries of the patient, as validated by digital subtraction angiography.
  
  
  
  Two multiple refocused VS magnetization preparations with shifted excitation profiles yield artifact-free peripheral angiograms at 3T. Magn Reson Med 76:466-477, 2016. © 2015 Wiley Periodicals, Inc.
authors: Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, Maryland, USA.
authors: Taehoon
authors: T
authors: Shin
authors: The Russel H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.|F.M. Kirby Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.
authors: Qin
authors: Q
authors: Qin
authors: Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, South Korea.|Department of Biomedical Engineering, Sungkyunkwan University, Suwon, South Korea.
authors: Jang-Yeon
authors: JY
authors: Park
authors: Division of Vascular and Endovascular Surgery, University of Maryland, Baltimore, Maryland, USA.
authors: Robert S
authors: RS
authors: Crawford
authors: Division of Cardiovascular Medicine, University of Maryland, Baltimore, Maryland, USA.
authors: Sanjay
authors: S
authors: Rajagopalan
mesh_terms: D000465:Algorithms; D016477:Artifacts; D003287:Contrast Media; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted
chemical_list: D003287:Contrast Media
keywords: non-contrast-enhanced MR angiography at 3T; peripheral angiography; velocity-selective magnetization preparation