title: Copper-chiral camphor β-amino alcohol complex catalyzed asymmetric Henry reaction.
abstract: Four novel chiral amino alcohols were synthesized from D-(+)-camphor and utilized as ligands in a Cu(I)-catalyzed asymmetric Henry reaction. The reactions were carried out under mild conditions with excellent enantioselectivities and moderate yields without the exclusion of air or moisture. The highest enantioselectivity was observed up to 94% enantiomeric excess (ee) with ligand in toluene at room temperature.
authors: Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi, People's Republic of China.
authors: Feng
authors: F
authors: Xu
authors: Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi, People's Republic of China.
authors: Chao
authors: C
authors: Lei
authors: Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi, People's Republic of China.
authors: Lei
authors: L
authors: Yan
authors: Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi, People's Republic of China.
authors: Jingxuan
authors: J
authors: Tu
authors: Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, Shaanxi, People's Republic of China.
authors: Gaoqiang
authors: G
authors: Li
keywords: Henry reaction; amino alcohol; camphor; copper(I) complexes; enantioselectivities