title: Choice of ICD-10 codes for the identification of acute coronary syndrome in the French hospitalization database.
abstract: The objective of this study was to evaluate the performance of the ICD-10 (International Classification of Diseases and Related Health Problems, 10(th) Edition) coding in the French hospitalization database (PMSI) to identify acute coronary syndrome (ACS) occurrence. Eligible hospitalizations were those that occurred at the Bordeaux teaching hospitals between 1 January 2011 and 31 December 2011 and had one of the ICD-10 codes related to ischaemic heart diseases (I20 to I25, excluding I23 and I25.2). Among these, 100 hospitalizations were randomly selected; for each case, the ACS diagnosis was confirmed/excluded after medical file examination by an independent events validation committee and the performance of codes, and combinations of codes, to identify ACS was evaluated by calculating the positive predictive value (PPV). Of the individual codes, I20.0, I21 and I24 had the highest PPV; 100.0% for I24 (95%CI [15.8-100.0]); 90.0% for I21 (95%CI [76.3-97.2]); and 66.7% for I20.0 (95%CI [38.4-88.2]). The combination of I20.0 or I24 codes was able to identify 12 of the 56 validated ACS cases with a PPV of 70.6% (95%CI [44.0-89.7]), the combination of I21 or I24 identified 38 cases with a PPV of 90.5% (95%CI [77.4-97.3]), the combination of I20.0 or I21 identified 46 cases with a PPV of 83.6% (95%CI [71.2-92.2]), and the combination of I20.0, I21 or I24 identified 48 cases with a PPV of 84.2% (95%CI [72.1-92.5]). The combination of I20.0, I21 or I24 codes had the best performance to identify occurrence of ACS in the French hospitalization database.
authors: Université de Bordeaux, Bordeaux, F-33076, France.|CIC Bordeaux CIC1401, Bordeaux, F-33076, France.|INSERM U657, Bordeaux, F-33076, France.|CHU Bordeaux, Service de Pharmacologie Clinique, Bordeaux, F-33076, France.
authors: Julien
authors: J
authors: Bezin
authors: Université de Bordeaux, Bordeaux, F-33076, France.|CIC Bordeaux CIC1401, Bordeaux, F-33076, France.|CHU Bordeaux, Service de Pharmacologie Clinique, Bordeaux, F-33076, France.
authors: Pierre-Olivier
authors: PO
authors: Girodet
authors: Université de Bordeaux, Bordeaux, F-33076, France.|ADERA, Pessac, F-33608, France.
authors: Sahondra
authors: S
authors: Rambelomanana
authors: Université de Bordeaux, Bordeaux, F-33076, France.|CHU Bordeaux, Service de Pharmacologie Clinique, Bordeaux, F-33076, France.
authors: Maëlys
authors: M
authors: Touya
authors: Université de Bordeaux, Bordeaux, F-33076, France.|CHU Bordeaux, Service de Pharmacologie Clinique, Bordeaux, F-33076, France.
authors: Paul
authors: P
authors: Ferreira
authors: CHU Bordeaux, Service d'Information Médicale, Pôle de Santé Publique, Bordeaux, F-33076, France.
authors: Véronique
authors: V
authors: Gilleron
authors: Université de Bordeaux, Bordeaux, F-33076, France.|ADERA, Pessac, F-33608, France.
authors: Philip
authors: P
authors: Robinson
authors: Université de Bordeaux, Bordeaux, F-33076, France.|CIC Bordeaux CIC1401, Bordeaux, F-33076, France.|INSERM U657, Bordeaux, F-33076, France.|CHU Bordeaux, Service de Pharmacologie Clinique, Bordeaux, F-33076, France.
authors: Nicholas
authors: N
authors: Moore
authors: Université de Bordeaux, Bordeaux, F-33076, France.|CIC Bordeaux CIC1401, Bordeaux, F-33076, France.|INSERM U657, Bordeaux, F-33076, France.|CHU Bordeaux, Service de Pharmacologie Clinique, Bordeaux, F-33076, France.
authors: Antoine
authors: A
authors: Pariente
mesh_terms: D054058:Acute Coronary Syndrome / Q000453:epidemiology*; D000368:Aged; D003430:Cross-Sectional Studies; D016208:Databases, Factual; D005260:Female; D005602:France / Q000453:epidemiology; D006760:Hospitalization; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D011237:Predictive Value of Tests
keywords: acute coronary syndrome; administrative data; positive predictive value; validation