title: Evaluation of the Postmortem Glucose and Glycogen Levels in Hepatic, Renal, Muscle, and Brain Tissues: Is It Possible to Estimate Postmortem Interval Using These Parameters?
abstract: The aim of our study was to investigate the postmortem levels of glucose and glycogen in hepatic, renal, muscle, and brain tissues and then examine the changes in those levels that could be useful for estimating postmortem interval. We established an animal model. Seventy female BALB/c albino mice were used in this study. After being sacrificed, the mice were randomly divided into six groups according to time elapsed since death (Group 1: 0 h; Group 2: 12 h; Group 3: 24 h; Group 4: 36 h; Group 5: 48 h; and Group 6: 60 h). Glucose levels were significantly different between groups for all tissues studied. Slope of the change per unit time was higher for the hepatic glucose levels. Based on these results, it is possible to estimate postmortem interval using postmortem glucose levels in hepatic tissue. Tissue-specific assessment may contribute valuable information to postmortem interval studies.
authors: Haseki Training and Research Hospital, Medical Biochemistry Laboratory, Millet Street, Istanbul, 34096, Turkey.
authors: Alper
authors: A
authors: Gümüş
authors: Turkey Forensic Medicine Institution, Kastamonu Office, Kastamonu, Turkey.
authors: Burak
authors: B
authors: Gümüş
authors: Forensic Medicine Department, Karadeniz Technical University, Trabzon, Turkey.
authors: Erdal
authors: E
authors: Özer
authors: Haseki Training and Research Hospital, Medical Biochemistry Laboratory, Millet Street, Istanbul, 34096, Turkey.
authors: Esma
authors: E
authors: Yücetaş
authors: Urology Department, Istanbul Training and Research Hospital, Istanbul, Turkey.
authors: Uğur
authors: U
authors: Yücetaş
authors: Haseki Training and Research Hospital, Medical Biochemistry Laboratory, Millet Street, Istanbul, 34096, Turkey.
authors: Emin
authors: E
authors: Düz
authors: Haseki Training and Research Hospital, Medical Biochemistry Laboratory, Millet Street, Istanbul, 34096, Turkey.
authors: Soner
authors: S
authors: Sarı
authors: Haseki Training and Research Hospital, Medical Biochemistry Laboratory, Millet Street, Istanbul, 34096, Turkey.
authors: Macit
authors: M
authors: Koldaş
mesh_terms: D000818:Animals; D001344:Autopsy; D001921:Brain; D001923:Brain Chemistry; D005260:Female; D005947:Glucose / Q000032:analysis*; D006003:Glycogen / Q000032:analysis*; D051379:Mice; D011180:Postmortem Changes
chemical_list: D006003:Glycogen; D005947:Glucose
keywords: forensic science; glucose; glycogen; postmortem chemistry; postmortem interval; thanatochemistry