title: Clarivein mechanochemical ablation of the great and small saphenous vein: Early treatment outcomes of two hospitals.
abstract: OBJECTIVE
  Mechanochemical endovenous ablation is a novel technique for the treatment of great saphenous vein and small saphenous vein incompetence which combines mechanical injury of the endothelium with simultaneous infusion of liquid sclerosant. The main objective of this study was to evaluate early occlusion.
  
  
  METHODS
  All consecutive patients who were eligible for the treatment with mechanochemical endovenous ablation were included. Inclusion period was from the introduction of the device in the hospitals (September 2011 and December 2011) until December 2012.
  
  
  RESULTS
  A total of 449 patients were included representing 570 incompetent veins. In 506 treated veins, duplex ultrasonography was performed at follow-up: 457 veins (90%) were occluded at a follow-up of 6 to 12 weeks. In univariate and multivariate analysis, failure of treated great saphenous vein was associated with saphenofemoral junction incompetence (OR 4; 95% CI 1.0-17.1, P = 0.049).
  
  
  CONCLUSIONS
  The Clarivein device proves to be safe and had a high short-term technical effectiveness.
authors: Department of Surgery, VU University Medical Centre, Amsterdam, The Netherlands c.deijen@vumc.nl.
authors: Charlotte L
authors: CL
authors: Deijen
authors: Department of Surgery, Rode Kruis Ziekenhuis, Beverwijk, The Netherlands.
authors: Michiel A
authors: MA
authors: Schreve
authors: Department of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
authors: Jan
authors: J
authors: Bosma
authors: Department of Surgery, Rode Kruis Ziekenhuis, Beverwijk, The Netherlands.
authors: A Jorianne
authors: AJ
authors: de Nie
authors: Department of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
authors: Vanessa J
authors: VJ
authors: Leijdekkers
authors: Department of Surgery, Rode Kruis Ziekenhuis, Beverwijk, The Netherlands.
authors: Peter J
authors: PJ
authors: van den Akker
authors: Department of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
authors: Anco
authors: A
authors: Vahl
mesh_terms: D055011:Ablation Techniques / Q000295:instrumentation / Q000379:methods; D000328:Adult; D000368:Aged; D004730:Endothelium, Vascular / Q000293:injuries / Q000473:pathology; D057510:Endovascular Procedures / Q000295:instrumentation / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012501:Saphenous Vein / Q000473:pathology / Q000601:surgery*; D014689:Venous Insufficiency / Q000473:pathology / Q000601:surgery*
keywords: Clarivein; endovenous ablation; incompetent veins; mechanochemical endovenous ablation; varicose veins; venous insufficiency