title: Intravitreal Triamcinolone Injection for Uveitic Macular Edema: A Randomized Clinical Study.
abstract: OBJECTIVE
  To evaluate the additive effect of intravitrial triamcinolone (TA) injection in uveitic macular edema compared to systemic anti-inflammatory treatment only.
  
  
  METHODS
  Patients were randomized into the intravitreal TA injection group and the sham group. All patients received systemic anti-inflammatory treatment with follow-up monthly to 6 months, with additional treatment as needed.
  
  
  RESULTS
  Fifty eyes of 50 patients were enrolled. Central foveal thickness decreased significantly from month 1 in the TA group, and from month 3 in the sham group. Parafoveal area thickness significantly decreased in both groups from month 1, with greater decrease in the TA group at months 2 and 3. Leakage area on fluorescein angiography was significantly smaller in the TA group at months 1 to 3. Intraocular pressure increased in the TA group at months 1 and 2.
  
  
  CONCLUSIONS
  Intravitreal TA injection showed earlier reduction of leakage and retinal edema compared to systemic anti-inflammatory treatment alone.
authors: a Department of Ophthalmology , Seoul National University Hospital , Seoul , South Korea .|b Department of Ophthalmology , Seoul National University Hospital Gangnam Center , Seoul , South Korea , and.
authors: Joo Young
authors: JY
authors: Shin
authors: a Department of Ophthalmology , Seoul National University Hospital , Seoul , South Korea .|c Sensory Organs Institute, Medical Research Center, Seoul National University , Seoul , South Korea.
authors: Hyeong Gon
authors: HG
authors: Yu
mesh_terms: D004311:Double-Blind Method; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D058449:Intravitreal Injections; D008269:Macular Edema / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*; D014605:Uveitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide
keywords: Intravitreal injection; macular edema; steroid; triamcinolone; uveitis