title: Platelets in the pathogenesis of acute respiratory distress syndrome.
abstract: Platelets have an emerging and incompletely understood role in a myriad of host immune responses, extending their role well beyond regulating thrombosis. Acute respiratory distress syndrome is a complex disease process characterized by a range of pathophysiologic processes including oxidative stress, lung deformation, inflammation, and intravascular coagulation. The objective of this review is to summarize existing knowledge on platelets and their putative role in the development and resolution of lung injury.
authors: Department of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota; and.
authors: Hemang
authors: H
authors: Yadav
authors: Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota kor.daryl@mayo.edu.
authors: Daryl J
authors: DJ
authors: Kor
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000276:immunology* / Q000473:pathology; D004211:Disseminated Intravascular Coagulation / Q000276:immunology* / Q000473:pathology; D006801:Humans; D008168:Lung / Q000276:immunology* / Q000473:pathology; D018384:Oxidative Stress / Q000276:immunology*; D012128:Respiratory Distress Syndrome / Q000276:immunology* / Q000473:pathology
keywords: ALI; ARDS; aspirin; lung injury; platelet