title: Identifying Cognitive States Using Regularity Partitions.
abstract: Functional Magnetic Resonance (fMRI) data can be used to depict functional connectivity of the brain. Standard techniques have been developed to construct brain networks from this data; typically nodes are considered as voxels or sets of voxels with weighted edges between them representing measures of correlation. Identifying cognitive states based on fMRI data is connected with recording voxel activity over a certain time interval. Using this information, network and machine learning techniques can be applied to discriminate the cognitive states of the subjects by exploring different features of data. In this work we wish to describe and understand the organization of brain connectivity networks under cognitive tasks. In particular, we use a regularity partitioning algorithm that finds clusters of vertices such that they all behave with each other almost like random bipartite graphs. Based on the random approximation of the graph, we calculate a lower bound on the number of triangles as well as the expectation of the distribution of the edges in each subject and state. We investigate the results by comparing them to the state of the art algorithms for exploring connectivity and we argue that during epochs that the subject is exposed to stimulus, the inspected part of the brain is organized in an efficient way that enables enhanced functionality.
authors: Department of Industrial and Systems Engineering, College of Engineering, University of Florida, Gainesville, Florida, United States of America; Department of Biomedical Engineering, College of Engineering, University of Florida, Gainesville, Florida, United States of America.
authors: Ioannis
authors: I
authors: Pappas
authors: Department of Industrial and Systems Engineering, College of Engineering, University of Florida, Gainesville, Florida, United States of America.
authors: Panos
authors: P
authors: Pardalos
mesh_terms: D000465:Algorithms; D001921:Brain / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D016000:Cluster Analysis; D003071:Cognition; D003196:Computer Graphics; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging; D009415:Nerve Net / Q000502:physiology