title: Epidemiology and definition of inappropriate sinus tachycardia.
abstract: Inappropriate sinus tachycardia (IST) is a clinical syndrome lacking formal diagnostic criteria. It is generally defined as an elevated resting heart rate (HR; >90-100 bpm) with an exaggerated response to physical or emotional stress and a clearly sinus mechanism. Clinical manifestations are broad from a complete lack of symptoms to incapacitating incessant tachycardia. Now understood to be relatively prevalent, it is observed to have a generally benign prognosis, though symptoms may persist for years. Whether IST is a single discrete entity or a heterogeneous condition with overlap to other syndromes such as postural orthostatic tachycardia syndrome remains a matter of debate.
authors: San Francisco VA Medical Center, 4150 Clement Street, 111C, San Francisco, CA, 94121, USA. cara.pellegrini@va.gov.|University of California San Francisco, San Francisco, CA, USA. cara.pellegrini@va.gov.
authors: Cara N
authors: CN
authors: Pellegrini
authors: University of California San Francisco, San Francisco, CA, USA.
authors: Melvin M
authors: MM
authors: Scheinman
mesh_terms: D017677:Age Distribution; D015984:Causality; D015897:Comorbidity; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D006339:Heart Rate; D006801:Humans; D054972:Postural Orthostatic Tachycardia Syndrome / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution; D013315:Stress, Psychological / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology*; D063189:Symptom Assessment / Q000379:methods*; D013577:Syndrome; D013616:Tachycardia, Sinus / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology*; D009626:Terminology as Topic
keywords: Clinical syndrome; Epidemiology; Inappropriate sinus tachycardia; Postural orthostatic tachycardia syndrome