title: Phaeochromocytoma presenting with pseudo-intestinal obstruction and lactic acidosis.
abstract: Phaeochromocytomas are rare neuroendocrine tumours with variable clinical signs and symptoms. Hypertension, tachycardia, sweating and headaches are cardinal manifestations. Although nausea and abdominal pain are the more common gastrointestinal features, rare gastrointestinal spectrums have been reported that can mimic abdominal emergencies. Metabolic effects of hypercatecholaminaemia are vast and one such rare presentation is lactic acidosis. We describe a case of phaeochromocytoma presenting with both intestinal pseudo-obstruction as well as lactic acidosis. This case report highlights the importance of having a high index of suspicion for and early recognition of the gastrointestinal and metabolic manifestations of phaeochromocytomas.
authors: Department of Endocrinology, Singapore General Hospital, Singapore.
authors: Peng Chin
authors: PC
authors: Kek
authors: Department of Endocrinology, Singapore General Hospital, Singapore.
authors: Emily Tse Lin
authors: ET
authors: Ho
authors: Department of Endocrinology, Singapore General Hospital, Singapore.
authors: Lih Ming
authors: LM
authors: Loh
mesh_terms: D015746:Abdominal Pain; D000140:Acidosis, Lactic / Q000150:complications*; D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000175:diagnosis; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D050171:Dyslipidemias / Q000150:complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D007418:Intestinal Pseudo-Obstruction / Q000150:complications*; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000150:complications* / Q000175:diagnosis; D010673:Pheochromocytoma / Q000150:complications* / Q000175:diagnosis; D011860:Radiography, Abdominal
keywords: intestinal pseudo-obstruction; lactic acidosis; phaeochromocytoma