title: In response to Melgari et al. "hERG potassium channel inhibition by ivabradine requires channel gating".
authors: Libin Cardiovascular Institute, Department of Medicine, University of Calgary, AB, Canada.
authors: James P
authors: JP
authors: Lees-Miller
authors: Libin Cardiovascular Institute, Department of Medicine, University of Calgary, AB, Canada.
authors: Jiqing
authors: J
authors: Guo
authors: Centre for Molecular Simulation, Department of Biological Sciences, University of Calgary, AB, Canada.
authors: Yibo
authors: Y
authors: Wang
authors: Centre for Molecular Simulation, Department of Biological Sciences, University of Calgary, AB, Canada.
authors: Laura L
authors: LL
authors: Perissinotti
authors: Centre for Molecular Simulation, Department of Biological Sciences, University of Calgary, AB, Canada. Electronic address: snoskov@ucalgary.ca.
authors: Sergei Y
authors: SY
authors: Noskov
authors: Libin Cardiovascular Institute, Department of Medicine, University of Calgary, AB, Canada. Electronic address: hduff@ucalgary.ca.
authors: Henry J
authors: HJ
authors: Duff
mesh_terms: D000818:Animals; D001552:Benzazepines / Q000494:pharmacology*; D051638:Ether-A-Go-Go Potassium Channels / Q000037:antagonists & inhibitors*; D006801:Humans; D064428:Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels / Q000037:antagonists & inhibitors*; D032383:Myocytes, Cardiac / Q000502:physiology*; D026902:Potassium Channel Blockers / Q000494:pharmacology*
chemical_list: D001552:Benzazepines; D051638:Ether-A-Go-Go Potassium Channels; D064428:Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; D026902:Potassium Channel Blockers
keywords: Ivabradine; Potassium channels; Tonic block; hERG KCNH2