title: Differential behaviour of cationic triphenylamine derivatives in fixed and living cells: triggering and imaging cell death.
abstract: Triphenylamines are on/off fluorescent DNA minor groove binders, allowing nuclear staining of fixed cells. By contrast, they accumulate in the cytoplasm of living cells and efficiently trigger cell apoptosis upon prolonged visible light irradiation. This process occurs concomitantly with their subcellular re-localization to the nucleus, enabling fluorescence imaging of apoptosis.
authors: LBPA, ENS Cachan, CNRS UMR8113, IDA FR3242, F-94235 Cachan, France. deprez@lbpa.ens-cachan.fr.
authors: R
authors: R
authors: Chennoufi
authors: H
authors: H
authors: Bougherara
authors: N
authors: N
authors: Gagey-Eilstein
authors: B
authors: B
authors: Dumat
authors: E
authors: E
authors: Henry
authors: F
authors: F
authors: Subra
authors: F
authors: F
authors: Mahuteau-Betzer
authors: P
authors: P
authors: Tauc
authors: M-P
authors: MP
authors: Teulade-Fichou
authors: E
authors: E
authors: Deprez
mesh_terms: D000814:Aniline Compounds / Q000494:pharmacology*; D002412:Cations; D016923:Cell Death; D045744:Cell Line, Tumor; D006801:Humans
chemical_list: D000814:Aniline Compounds; D002412:Cations