title: Acquired enophthalmos with systemic lupus erythematosus.
abstract: Ocular involvement sometimes occurs with systemic lupus erythematosus (SLE) but enophthalmos with SLE is rare. We report a case of enophthalmos with SLE. A 25-year-old male was admitted for two weeks of fever, sore throat, arthralgia, chest pain and right arm weakness with pain. We diagnosed him with SLE with malar rash, arthritis, pleural effusion, proteinuria, leukopenia, positive antinuclear antibody, anti-dsDNA, and lupus anticoagulant. The patient was prescribed high-dose prednisolone and hydroxychloroquine 400 mg. One week after discharge, he complained about a sensation of a sunken right eye. CT showed right enophthalmos, a post-inflammatory change and chronic inflammation. Proteinuria increased to 3.8 g/day after the patient stopped taking prednisolone. Cyclophosphamide therapy was administered for three months without improvement. We decided to restart prednisolone and change cyclophosphamide to mycophenolate mofetil. Proteinuria decreased but enophthalmos remains as of this reporting.
authors: Gachon University GiI Hospital, Department of Rheumatology, Incheon, the Republic of Korea.
authors: K R
authors: KR
authors: Park
authors: Gachon University GiI Hospital, Department of Rheumatology, Incheon, the Republic of Korea.
authors: M R
authors: MR
authors: Seo
authors: Gachon University GiI Hospital, Department of Rheumatology, Incheon, the Republic of Korea.
authors: H J
authors: HJ
authors: Ryu
authors: Gachon University Gil Hospital, Department of Ophthalmology, Incheon, the Republic of Korea.
authors: M J
authors: MJ
authors: Chi
authors: Gachon University GiI Hospital, Department of Rheumatology, Incheon, the Republic of Korea.
authors: H J
authors: HJ
authors: Baek
authors: Gachon University GiI Hospital, Department of Rheumatology, Incheon, the Republic of Korea hjchoi@gachon.ac.kr.
authors: H J
authors: HJ
authors: Choi
mesh_terms: D000328:Adult; D057915:Drug Substitution; D004359:Drug Therapy, Combination; D015841:Enophthalmos / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents
keywords: Enophthalmos; post-inflammation; systemic lupus erythematosus