title: Dietary Patterns and Risk of Frailty in Chinese Community-Dwelling Older People in Hong Kong: A Prospective Cohort Study.
abstract: Dietary pattern analysis is an emerging approach to investigate the association between diet and frailty. This study examined the association of dietary patterns with frailty in 2724 Chinese community-dwelling men and women aged > 65 years. Baseline dietary data were collected using a food frequency questionnaire between 2001 and 2003. Adherence to a priori dietary patterns, including the Diet Quality Index-International (DQI-I) and the Mediterranean Diet Score (MDS) was assessed. Factor analysis identified three a posteriori dietary patterns, namely "vegetables-fruits", "snacks-drinks-milk products", and "meat-fish". Incident frailty was defined using the FRAIL scale. Binary logistic regression was applied to examine the associations between dietary patterns and four-year incident frailty. There were 31 (1.1%) incident frailty cases at four years. Every 10-unit increase in DQI-I was associated with 41% reduced risk of frailty in the sex- and age-adjusted model (odds ratio (OR) (95% confidence interval (CI)): 0.59 (0.42-0.85), p = 0.004). The association attenuated in the multivariate adjusted model (0.69 (0.47-1.02), p = 0.056). No association between other dietary patterns and incident frailty was observed. Our study showed that a better diet quality as characterized by higher DQI-I was associated with lower odds of developing frailty. The contribution of MDS or a posteriori dietary patterns to the development of frailty in Chinese older people remains to be explored.
authors: Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, China. ruthchansm@cuhk.edu.hk.
authors: Ruth
authors: R
authors: Chan
authors: Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Shatin, Hong Kong, China. jason-leung@cuhk.edu.hk.
authors: Jason
authors: J
authors: Leung
authors: Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, China. jeanwoowong@cuhk.edu.hk.
authors: Jean
authors: J
authors: Woo
mesh_terms: D000368:Aged; D044466:Asian People; D002136:Calcium, Dietary / Q000008:administration & dosage; D003611:Dairy Products; D004032:Diet; D038441:Diet, Mediterranean; D004043:Dietary Fiber / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D002149:Energy Intake; D005260:Female; D005500:Follow-Up Studies; D063427:Food Quality; D016330:Frail Elderly; D005638:Fruit; D006723:Hong Kong; D006801:Humans; D008019:Life Style; D016015:Logistic Models; D008297:Male; D009043:Motor Activity; D015999:Multivariate Analysis; D015596:Nutrition Assessment; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D014675:Vegetables
chemical_list: D002136:Calcium, Dietary; D004043:Dietary Fiber; D004044:Dietary Proteins
keywords: Chinese; dietary pattern; frailty