title: [Relationship between environmental tobacco smoke and lung cancer risk among nonsmokers in China: A meta-analysis].
abstract: OBJECTIVE
  To investigate the relationship between the environmental tobacco smoke (ETS) and lung cancer by Meta-analysis.
  
  
  METHODS
  We used "lung cancer/lung neoplasm", "non-smoking/non-smoker", "China/Chinese", "case-control/case control", "risk factor", "environmental tobacco smoke/passive smoking" as key words, to search papers in databases including Chinese BioMedical Literature (CBM), China National Knowledge Internet (CNKI), Wanfang, Vip Citation Databases (VIP), PubMed and Web of Science databases, and collected the case-control studies on ETS and lung cancer among Chinese non-smokers from January 1999 to December 2013. A total of 129 research papers were collected. RevMan 5.2 software was used to calculate combined odds radio (OR) and 95% CI.
  
  
  RESULTS
  Qualified 18 literatures were included, total cases 6 145 and controls 8 132. Consolidated results showed that ETS exposure could increase the risk of lung cancer, combined OR (95% CI) = 1.52 (1.42-1.64). Stratified analysis showed that ETS exposure was found to be significantly associated with an increasing risk of the lung cancer on non-smoking women and men, and combined OR (95% CI) were 1.58 (1.42-1.75) and 1.34 (1.08-1.65), respectively; the ETS exposure from family or the working environment could increase the risk of lung cancer, and combined OR (95% CI) were 1.48 (1.20-1.82) and 1.38 (1.13-1.69) respectively; childhood exposure and adult exposure were no significant statistical significance, and combined OR (95% CI) were 1.37 (0.98-1.91), and 1.34 (0.97-1.85) respectively.
  
  
  CONCLUSIONS
  Environmental tobacco smoke exposure was a significant risk factor of lung cancer among non-smokers in China.
authors: Department of Disaster and Emergency Medicine, East Hospital, Tongji University, Shanghai 200092, China.
authors: Xin
authors: X
authors: Fu
authors: Department of Disaster and Emergency Medicine, East Hospital, Tongji University, Shanghai 200092, China.
authors: Tienan
authors: T
authors: Feng
authors: Department of Disaster and Emergency Medicine, East Hospital, Tongji University, Shanghai 200092, China.
authors: Minfang
authors: M
authors: Wu
authors: Department of Disaster and Emergency Medicine, East Hospital, Tongji University, Shanghai 200092, China.
authors: Ludan
authors: L
authors: Zhang
authors: Department of Disaster and Emergency Medicine, East Hospital, Tongji University, Shanghai 200092, China; Email: jch@tongji.edu.cn.
authors: Chenghua
authors: C
authors: Jiang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002681:China; D005260:Female; D006801:Humans; D008175:Lung Neoplasms; D008297:Male; D012307:Risk Factors; D014028:Tobacco Smoke Pollution
chemical_list: D014028:Tobacco Smoke Pollution