title: Screening for Pancreatic Cancer.
abstract: Neither extended surgery nor extended indication for surgery has improved survival in patients with pancreatic cancer. According to autopsy studies, presumably 90% are metastatic. The only cure is complete removal of the tumor at an early stage before it becomes a systemic disease or becomes invasive. Early detection and screening of individuals at risk is currently under way. This article reviews the evidence and methods for screening, either familial or sporadic. Indication for early-stage surgery and precursors are discussed. Surgeons should be familiar with screening because it may provide patients with a chance for cure by surgical resection.
authors: Department of Surgery, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-ku, Tokyo 173-8605, Japan.
authors: Keita
authors: K
authors: Wada
authors: Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Department of Surgery, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-5807, Japan. Electronic address: takaori@kuhp.kyoto-u.ac.jp.
authors: Kyoichi
authors: K
authors: Takaori
authors: St. Luke's Center for Pancreatic and Liver Disease, 100 E, Idaho St, Boise, ID 83712, USA.
authors: L William
authors: LW
authors: Traverso
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis* / Q000601:surgery; D021441:Carcinoma, Pancreatic Ductal / Q000175:diagnosis* / Q000601:surgery; D002291:Carcinoma, Papillary / Q000175:diagnosis* / Q000601:surgery; D055088:Early Detection of Cancer / Q000379:methods*; D006801:Humans; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000601:surgery; D018570:Risk Assessment; D012307:Risk Factors
keywords: Familial pancreatic cancer; Intraductal papillary mucinous neoplasm; Pancreatic cancer; Pancreatic intraepithelial neoplasia; Screening