title: The Influence of Posttraumatic Stress Disorder on Treatment Outcomes of Patients With Borderline Personality Disorder.
abstract: The aim of this study was to determine the influence of posttraumatic stress disorder (PTSD) on treatment outcomes in patients with borderline personality disorder (BPD). Participants were 180 individuals diagnosed with BPD enrolled in a randomized controlled trial that compared the clinical and cost effectiveness of dialectical behavior therapy (DBT) and general psychiatric management (GPM). Multilevel linear models and generalized linear models were used to compare clinical outcomes of BPD patients with and without PTSD. BPD patients with comorbid PTSD reported significantly higher levels of global psychological distress at baseline and end of treatment compared to their non-PTSD counterparts. Both groups evidenced comparable rates of change on suicide attempts and non-suicidal self-injury (NSSI), global psychological distress, and BPD symptoms over the course of treatment and post-treatment follow-up. DBT and GPM were effective for BPD patients with and without PTSD across a broad range of outcomes.
authors: Centre for Addiction and Mental Health, Toronto, Canada.|Department of Psychiatry, University of Toronto.
authors: Tali
authors: T
authors: Boritz
authors: Centre for Addiction and Mental Health, Toronto, Canada.|Department of Psychology, York University, Toronto.
authors: Ryan
authors: R
authors: Barnhart
authors: Centre for Addiction and Mental Health, Toronto, Canada.|Department of Psychiatry, University of Toronto.
authors: Shelley F
authors: SF
authors: McMain
mesh_terms: D000328:Adult; D001521:Behavior Therapy / Q000191:economics / Q000379:methods*; D001883:Borderline Personality Disorder / Q000191:economics / Q000453:epidemiology / Q000628:therapy*; D015897:Comorbidity; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D016728:Self-Injurious Behavior / Q000191:economics / Q000453:epidemiology / Q000628:therapy*; D013313:Stress Disorders, Post-Traumatic / Q000191:economics / Q000453:epidemiology / Q000628:therapy*; D013406:Suicide, Attempted / Q000191:economics / Q000517:prevention & control* / Q000706:statistics & numerical data; D055815:Young Adult