title: The role of coffee consumption on the 10-year (2004-2014) Acute Coronary Syndrome (ACS) incidence among cardiac patients: the GREECS observational study.
abstract: The association between long-term coffee consumption and 10-year cardiovascular disease incidence among Acute Coronary Syndrome (ACS) patients was evaluated. From 2003 to 2004, 2172 ACS consecutive patients from six major Greek hospitals were enrolled. During 2013-2014, the 10-year follow-up was performed (88% participation rate) and recurrent fatal or non-fatal ACS was recorded. Baseline coffee consumption (cups/day) was assessed using a semi-quantitative Food Frequency Questionnaire. Multi adjusted analysis revealed that 1-2 cups of coffee/day versus no consumption had an adverse effect on the ACS incidence [odds ratio (OR) = 1.35, 95% confidence interval (CI) 1.01, 1.79]. In subgroup analysis, with hypertension as strata, only the normotensive reached significance. Odds ratios for 1-2 and ≥3 cups relative to no consumption were [OR = 1.66, 95% CI 1.07, 2.60] and [OR = 1.86, 95% CI 1.06, 3.27], respectively, after controlling for potential confounders. Thus, avoidance of coffee may be of high importance to ameliorate disease prognosis among cardiac patients.
authors: a Department of Nutrition and Dietetics , School of Health Science and Education, Harokopio University , Athens , Greece .
authors: Venetia
authors: V
authors: Notara
authors: a Department of Nutrition and Dietetics , School of Health Science and Education, Harokopio University , Athens , Greece .
authors: Demosthenes B
authors: DB
authors: Panagiotakos
authors: a Department of Nutrition and Dietetics , School of Health Science and Education, Harokopio University , Athens , Greece .
authors: Matina
authors: M
authors: Kouvari
authors: a Department of Nutrition and Dietetics , School of Health Science and Education, Harokopio University , Athens , Greece .
authors: Despoina
authors: D
authors: Tzanoglou
authors: a Department of Nutrition and Dietetics , School of Health Science and Education, Harokopio University , Athens , Greece .
authors: Georgia
authors: G
authors: Kouli
authors: b Cardiology Clinic, General Hospital of Chalkida , Chalkida , Greece .
authors: Yannis
authors: Y
authors: Mantas
authors: c Cardiology Clinic, General Hospital of Karditsa , Karditsa , Greece .
authors: Yannis
authors: Y
authors: Kogias
authors: d Cardiology Clinic, General Hospital of Zakynthos Island , Greece .
authors: Petros
authors: P
authors: Stravopodis
authors: e Cardiology Clinic, General Hospital of Lamia , Lamia , Greece .
authors: George
authors: G
authors: Papanagnou
authors: f Cardiology Clinic, General Hospital of Kalamata , Kalamata , Greece .
authors: Spyros
authors: S
authors: Zombolos
authors: g Department of Nursing , Technological Educational Institute of Athens .
authors: Fotοula
authors: F
authors: Babatsikou
authors: h Department of Public Health & Community Health , Technological Educational Institute of Athens , and.
authors: Charilaos
authors: C
authors: Koutis
authors: i First Cardiology Clinic, School of Medicine, University of Athens , Athens , Greece.
authors: Christos
authors: C
authors: Pitsavos
mesh_terms: D054058:Acute Coronary Syndrome / Q000453:epidemiology / Q000209:etiology*; D000368:Aged; D000369:Aged, 80 and over; D003069:Coffee / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors
chemical_list: D003069:Coffee
keywords: Cafe; cardiovascular risk; hypertension; recurrent cardiac episodes; secondary prevention