title: [Primary Central Nervous System Post-Transplant Lymphoproliferative Disorder in a Patient with Acute Lymphocytic Leukemia].
abstract: A 27-year-old woman with acute lymphocytic leukemia, who underwent allogeneic hematopoietic stem cell transplantation, complained of nausea and blurred vision 288 days after the transplantation. Intracranial tumors were identified on brain MRI. She received whole brain radiation after open biopsy, but she died. The tumors had characteristics of diffuse large B cell lymphoma, and she was finally diagnosed with primary central nervous system post-transplant lymphoproliferative disorder. This disease is rare and has a poor outcome. Therefore, accumulation of cases and establishment of treatments for this condition are urgently needed.
authors: First Dept. of Internal Medicine, Division of Hematology, Kansai Medical University.
authors: Yoshiko
authors: Y
authors: Azuma
authors: Aya
authors: A
authors: Nakaya
authors: Shinya
authors: S
authors: Fujita
authors: Masaaki
authors: M
authors: Hotta
authors: Yukie
authors: Y
authors: Fujita
authors: Hideaki
authors: H
authors: Yoshimura
authors: Takahisa
authors: T
authors: Nakanishi
authors: Atsushi
authors: A
authors: Satake
authors: Tomoki
authors: T
authors: Ito
authors: Kazuyoshi
authors: K
authors: Ishii
authors: Shosaku
authors: S
authors: Nomura
mesh_terms: D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D001932:Brain Neoplasms / Q000175:diagnosis; D002493:Central Nervous System Diseases / Q000209:etiology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000209:etiology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy*