title: Pre-operative effects of the administration of systemic corticosteroids combined with antibiotics on a lobular capillary hemangioma in the nasal cavity.
abstract: Lobular capillary hemangiomas (LCHs), also known as pyogenic granulomas, are benign, rapidly growing hemorrhagic lesions that usually develop in the oral or nasal cavities. In adults, LCHs occur in <5% of all pregnant women. A 30-year-old woman presented with a 4-month history of right-sided nasal obstruction and recurrent epistaxis 2 months post-partum. A fragile, pink-red lobulated tumor existed in the anterior portion of the right inferior turbinate; the biopsy revealed a LCH. Although the patient declined surgery using an external approach, treatment with systemic corticosteroids combined with antibiotics resulted in tumor regression and an endoscopic en bloc resection was possible. No recurrence has been noted to date (>1 year after surgery). Pre-operative treatment with systemic corticosteroids combined with antibiotics may be useful to induce tumor regression and to excise the lesion completely with an endoscopic approach.
authors: Department of Otorhinolaryngology/Head and Neck Surgery, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba City, Chiba 260-8670, Japan. Electronic address: thanazawa@faculty.chiba-u.jp.
authors: Toyoyuki
authors: T
authors: Hanazawa
authors: Department of Otorhinolaryngology/Head and Neck Surgery, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba City, Chiba 260-8670, Japan.
authors: Shuji
authors: S
authors: Yonekura
authors: Department of Otorhinolaryngology/Head and Neck Surgery, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba City, Chiba 260-8670, Japan.
authors: Hiroko
authors: H
authors: Nakamura
authors: Department of Otorhinolaryngology/Head and Neck Surgery, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba City, Chiba 260-8670, Japan.
authors: Akira
authors: A
authors: Fujikawa
authors: Department of Otorhinolaryngology/Head and Neck Surgery, Graduate School of Medicine, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba City, Chiba 260-8670, Japan.
authors: Yoshitaka
authors: Y
authors: Okamoto
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004724:Endoscopy; D004844:Epistaxis / Q000209:etiology / Q000628:therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D017789:Granuloma, Pyogenic / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D064704:Levofloxacin / Q000627:therapeutic use*; D009296:Nasal Cavity / Q000000981:diagnostic imaging; D015508:Nasal Obstruction / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy; D059747:Nasal Surgical Procedures; D009668:Nose Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D011239:Prednisolone / Q000627:therapeutic use*; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D064704:Levofloxacin; D011239:Prednisolone
keywords: Antibiotics; Corticosteroids; Lobular capillary hemangioma; Nasal cavity; Pyogenic granuloma