title: Enantioselective Organocatalytic Transfer Hydrogenation of 1,2-Dihydroquinoline through Formation of Aza-o-xylylene.
abstract: A new way of forming the aza-o-xylylene with easily accessible 1,2-dihydroquinolines as precursor has been developed. The presence of an electron-donating group at the proper position of 1,2-dihydroquinoline was crucial for protonation of the alkene through dearomatization with a simple Brønsted acid. The in situ forming reactive intermediate was trapped with Hantzsch ester to afford tetrahydroquinolines in excellent yield and enantioselectivity.
authors: Natural Products Research Center, Chengdu Institution of Biology Chinese Academy of Science Chendu, Sichuan 610041, China.
authors: Guangxun
authors: G
authors: Li
authors: Natural Products Research Center, Chengdu Institution of Biology Chinese Academy of Science Chendu, Sichuan 610041, China.
authors: Hongxin
authors: H
authors: Liu
authors: Natural Products Research Center, Chengdu Institution of Biology Chinese Academy of Science Chendu, Sichuan 610041, China.
authors: Gang
authors: G
authors: Lv
authors: College of Chemical Engineering, Sichuan University , Chendu Sichuan 610041, China.
authors: Yingwei
authors: Y
authors: Wang
authors: Natural Products Research Center, Chengdu Institution of Biology Chinese Academy of Science Chendu, Sichuan 610041, China.
authors: Qingquan
authors: Q
authors: Fu
authors: Natural Products Research Center, Chengdu Institution of Biology Chinese Academy of Science Chendu, Sichuan 610041, China.
authors: Zhuo
authors: Z
authors: Tang