title: Medical Treatment of Primary Canine Glaucoma.
abstract: Glaucoma is a painful and often blinding group of ocular diseases for which there is no cure. Although the definition of glaucoma is rapidly evolving, elevated intraocular pressure (IOP) remains the most consistent risk factor of glaucoma in the canine patient. Therapy should be aimed at neuroprotection. The mainstay of therapy focuses on reducing IOP and maintaining a visual and comfortable eye. This article discusses the most current ocular hypotensive agents, focusing on their basic pharmacology, efficacy at lowering IOP, and recommended use in the treatment of idiopathic canine glaucoma.
authors: VCA Capital Area Veterinary Emergency and Specialty, 1 Intervale Road, Concord, NH 03301, USA. Electronic address: aalario@gmail.com.
authors: Anthony F
authors: AF
authors: Alario
authors: Lloyd Veterinary Medical Center, Iowa State University College of Veterinary Medicine, 1600 16th Street, Ames, IA 50011, USA.
authors: Travis D
authors: TD
authors: Strong
authors: Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, 200 Westboro Road, North Grafton, MA 01536, USA.
authors: Stefano
authors: S
authors: Pizzirani
mesh_terms: D000322:Adrenergic Agonists / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D002257:Carbonic Anhydrase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D018679:Cholinergic Agonists / Q000008:administration & dosage / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D016503:Drug Delivery Systems / Q000662:veterinary; D064426:Gasotransmitters / Q000627:therapeutic use; D005901:Glaucoma / Q000188:drug therapy / Q000662:veterinary*; D008916:Miotics / Q000008:administration & dosage / Q000627:therapeutic use; D011453:Prostaglandins / Q000008:administration & dosage / Q000627:therapeutic use; D054460:rho-Associated Kinases / Q000037:antagonists & inhibitors
chemical_list: D000322:Adrenergic Agonists; D002257:Carbonic Anhydrase Inhibitors; D018679:Cholinergic Agonists; D064426:Gasotransmitters; D008916:Miotics; D011453:Prostaglandins; D054460:rho-Associated Kinases
keywords: Carbonic anhydrase inhibitors; Delivery systems; Glaucoma; Medical therapy; Novel therapies; Prostaglandin analogues