title: Factors associated with moderate or severe left atrioventricular valve regurgitation within 30 days of repair of complete atrioventricular septal defect.
abstract: BACKGROUND
  Left atrioventricular valve regurgitation is the most concerning residual lesion after surgical correction of atrioventricular septal defects.
  
  
  OBJECTIVE
  To determine factors associated with moderate or severe left atrioventricular valve regurgitation within 30 days of surgical repair of complete atrioventricular septal defect.
  
  
  METHODS
  We assessed the results of 53 consecutive patients 3 years-old and younger presenting with complete atrioventricular septal defect that were operated on at our practice between 2002 and 2010. The following variables were considered: age, weight, absence of Down syndrome, grade of preoperative atrioventricular valve regurgitation, abnormalities on the left atrioventricular valve and the use of annuloplasty. Median age was 6.7 months; median weight was 5.3 Kg; 86.8% had Down syndrome. At the time of preoperative evaluation, there were 26 cases with moderate or severe left atrioventricular valve regurgitation (49.1%). Abnormalities on the left atrioventricular valve were found in 11.3%; annuloplasty was performed in 34% of the patients.
  
  
  RESULTS
  At the time of postoperative evaluation, there were 21 cases with moderate or severe left atrioventricular valve regurgitation (39.6%). After performing a multivariate analysis, the only significant factor associated with moderate or severe left atrioventricular valve regurgitation was the absence of Down syndrome (P=0.03).
  
  
  CONCLUSIONS
  Absence of Down syndrome was associated with moderate or severe postoperative left atrioventricular valve regurgitation after surgical repair of complete atrioventricular septal defect at our practice.
authors: Department of Pediatrics and Pediatric Surgery, Hospital de Base, São José do Rio Preto Medical School, São José do Rio Preto, SP, BR.
authors: Marcelo Felipe
authors: MF
authors: Kozak
authors: Department of Pediatrics and Pediatric Surgery, Hospital de Base, São José do Rio Preto Medical School, São José do Rio Preto, SP, BR.
authors: Ana Carolina Leiroz Ferreira Botelho Maisano
authors: AC
authors: Kozak
authors: Department of Pediatrics and Pediatric Surgery, Hospital de Base, São José do Rio Preto Medical School, São José do Rio Preto, SP, BR.
authors: Carlos Henrique De
authors: CH
authors: Marchi
authors: Department of Cardiology, Hospital de Base, Hospital de Base, São José do Rio Preto Medical School, São José do Rio Preto, SP, BR.
authors: Sirio Hassem
authors: SH
authors: Sobrinho Junior
authors: Department of Pediatrics and Pediatric Surgery, Hospital de Base, São José do Rio Preto Medical School, São José do Rio Preto, SP, BR.
authors: Ulisses Alexandre
authors: UA
authors: Croti
authors: Department of Pediatrics and Pediatric Surgery, Hospital de Base, São José do Rio Preto Medical School, São José do Rio Preto, SP, BR.
authors: Airton Camacho
authors: AC
authors: Moscardini
mesh_terms: D000367:Age Factors; D001835:Body Weight; D002675:Child, Preschool; D004314:Down Syndrome / Q000503:physiopathology; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D008944:Mitral Valve Insufficiency / Q000209:etiology* / Q000503:physiopathology; D011183:Postoperative Complications / Q000209:etiology; D011184:Postoperative Period; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D013997:Time Factors; D016896:Treatment Outcome