title: Assessing the risk of recurrent venous thromboembolism--a practical approach.
abstract: Recurrent venous thromboembolism (VTE) is associated with increased morbidity and mortality. This risk is lowered by anticoagulation, with a large effect in the initial phase following the venous thromboembolic event, and with a smaller effect in terms of secondary prevention of recurrence when extended anticoagulation is performed. On the other hand, extended anticoagulation is associated with an increased risk of major bleeding and thus leads to morbidity and mortality. Therefore, it is necessary to assess the risk of recurrence for VTE on an individual basis, and a recommendation for secondary prophylaxis should be specifically based on risk calculation of recurrence of VTE and bleeding. In this review, we provide a comprehensive summary of relevant risk factors for recurrent VTE and a practical approach for assessing the risk of recurrence in daily practice.
authors: Division of Angiology, Medical University Clinic, Kantonsspital Aarau AG, Aarau, Switzerland.
authors: Jennifer
authors: J
authors: Fahrni
authors: Clinic for Angiology, University Hospital, University of Zurich, Zürich, Switzerland.
authors: Marc
authors: M
authors: Husmann
authors: Clinic for Angiology Oberaargau, Langenthal, Switzerland.
authors: Silvia B
authors: SB
authors: Gretener
authors: Division of Angiology, Medical University Clinic, Kantonsspital Aarau AG, Aarau, Switzerland.
authors: Hong H
authors: HH
authors: Keo
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects; D003661:Decision Support Techniques; D004334:Drug Administration Schedule; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D011237:Predictive Value of Tests; D012008:Recurrence; D018570:Risk Assessment; D012307:Risk Factors; D055502:Secondary Prevention / Q000379:methods; D013997:Time Factors; D016896:Treatment Outcome; D054556:Venous Thromboembolism / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control
chemical_list: D000925:Anticoagulants
keywords: hemorrhage; risk assessment; thrombosis