title: Changes in higher-order aberrations of intraocular lenses with intrascleral fixation.
abstract: OBJECTIVE
  To determine the higher-order aberrations of intraocular lenses (IOLs) that are extended and fixed intrasclerally.
  
  
  METHODS
  A computer-aided design system was used to calculate the length of an IOL when it was fixed to the sclera 2 mm posterior to the limbus in a Gullstrand eye model. An acrylic single-piece (SA60AT) or 2 three-piece IOLs (VA-60BBR; X-60) were fixed at lengths of 13, 14, 15 and 16 mm. A wavefront analyser was used to measure the higher-order aberrations within the central 3.0 and 5.2 mm optic diameters.
  
  
  RESULTS
  The length of the IOL with the intrascleral fixation was calculated to be 13.9-14.9 mm in the eye model. The astigmatic aberration of the three-piece VA-60BBR and X-60 IOLs increased significantly with an extension of the IOLs within the central 5.2 mm (both p<0.001) but not that of the single-piece SA60AT IOL. The coma aberration of the VA-60BBR IOL increased significantly within the central 5.2 mm with an increase in the extension (p=0.001) but not that of the SA60AT and X-60 IOLs. The astigmatic and coma aberrations were significantly greater within the central 5.2 mm than within the central 3.0 mm for all IOLs (p<0.05). The cylindrical power increased from 0.034 D to 0.082 D with extensions from 13 to 16 mm.
  
  
  CONCLUSIONS
  When three-piece IOLs are extended widely for intrascleral fixation, the astigmatic and coma aberrations increase but the degree of change should not alter the postoperative vision appreciably.
authors: Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.
authors: Naoko
authors: N
authors: Matsuki
authors: Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.
authors: Makoto
authors: M
authors: Inoue
authors: Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.
authors: Yuji
authors: Y
authors: Itoh
authors: Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan Nagamoto Eye Clinic, Tokyo, Japan.
authors: Toshiyuki
authors: T
authors: Nagamoto
authors: Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.
authors: Akito
authors: A
authors: Hirakata
mesh_terms: D000180:Acrylic Resins; D017076:Computer-Aided Design; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007910:Lenses, Intraocular; D008953:Models, Anatomic; D055095:Optics and Photonics; D012590:Sclera / Q000601:surgery*; D013536:Suture Techniques
chemical_list: D000180:Acrylic Resins
keywords: Imaging; Treatment Surgery