title: Carbohydrate mouth rinse enhances time to exhaustion during treadmill exercise.
abstract: Mouth rinsing with a CHO solution has been suggested to improve short (<1 h) endurance performance through central effect. We examined the effects of mouth rinsing with a CHO solution on running time to exhaustion on a treadmill. Six well-trained subjects ran to exhaustion at 85% VO2max, on three separate occasions. Subjects received either an 8% CHO solution or a placebo (PLA) every 15 min to mouth rinse (MR) or a 6% CHO solution to ingest (ING). Treatments were assigned in a randomized, counterbalanced fashion, with the mouth-rinsing treatments double-blinded. Blood samples were taken to assess glucose (Glu) and lactate (Lac), as well as the perceived exertion (RPE). Gas exchange and heart rate (HR) were collected during all trials. Subjects ran longer (P = 0·038) in both the MR (2583 ± 686 s) and ING (2625 ± 804 s) trials, compared to PLA (1935 ± 809 s), covering a greater distance (MR 9685 ± 3511·62 m; ING 9855 ± 4118·62; PLA 7295 ± 3727 m). RER was significantly higher in both ING and MR versus PLA. No difference among trials was observed for other metabolic or cardiovascular variables (VO2, Lac, Glu, HR), nor for RPE. Endurance capacity, based on time to exhaustion on a treadmill, was improved when either mouth rinsing or ingesting a CHO solution, compared to PLA.
authors: Biometrics Laboratory (LADEBIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors: Cindy
authors: C
authors: Fraga
authors: Physical Education Graduate Program, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors: Bruna
authors: B
authors: Velasques
authors: Exercise Physiology Laboratory, Lenoir-Rhyne University, Hickory, NC, USA.
authors: Alexander J
authors: AJ
authors: Koch
authors: Laboratory of Human Movement Studies, Universitary Foundation of Itaperuna, Itaperuna, Brazil.
authors: Marco
authors: M
authors: Machado
authors: Biometrics Laboratory (LADEBIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors: Dailson
authors: D
authors: Paulucio
authors: Physical Education Graduate Program, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors: Pedro
authors: P
authors: Ribeiro
authors: Biometrics Laboratory (LADEBIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.|Physical Education Graduate Program, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors: Fernando Augusto Monteiro Saboia
authors: FA
authors: Pompeu
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D001938:Brazil; D002241:Carbohydrates / Q000008:administration & dosage*; D004311:Double-Blind Method; D005080:Exercise Test; D006339:Heart Rate; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D008297:Male; D009067:Mouthwashes; D018763:Muscle Fatigue / Q000187:drug effects*; D010101:Oxygen Consumption; D010807:Physical Endurance / Q000187:drug effects*; D011659:Pulmonary Gas Exchange; D012420:Running; D013997:Time Factors; D055815:Young Adult
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D002241:Carbohydrates; D009067:Mouthwashes; D019344:Lactic Acid
keywords: endurance capacity; ergogenic aid; exercise; mouth wash; performance; running; supplementation