title: Routing of individual polymers in designed patterns.
abstract: Synthetic polymers are ubiquitous in the modern world, but our ability to exert control over the molecular conformation of individual polymers is very limited. In particular, although the programmable self-assembly of oligonucleotides and proteins into artificial nanostructures has been demonstrated, we currently lack the tools to handle other types of synthetic polymers individually and thus the ability to utilize and study their single-molecule properties. Here we show that synthetic polymer wires containing short oligonucleotides that extend from each repeat can be made to assemble into arbitrary routings. The wires, which can be more than 200 nm in length, are soft and bendable, and the DNA strands allow individual polymers to self-assemble into predesigned routings on both two- and three-dimensional DNA origami templates. The polymers are conjugated and potentially conducting, and could therefore be used to create molecular-scale electronic or optical wires in arbitrary geometries.
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.|Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors: Jakob Bach
authors: JB
authors: Knudsen
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Lei
authors: L
authors: Liu
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.|Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors: Anne Louise
authors: AL
authors: Bank Kodal
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.|Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors: Mikael
authors: M
authors: Madsen
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Qiang
authors: Q
authors: Li
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Jie
authors: http://orcid.org/0000-0002-7163-4022
authors: J
authors: Song
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.|Max Planck Institute of Biochemistry and Ludwig-Maximilians-Universität, Am Klopferspitz 18, 82152 Martinsreid, Munich, Germany.
authors: Johannes B
authors: JB
authors: Woehrstein
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.
authors: Shelley F J
authors: SF
authors: Wickham
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.|Max Planck Institute of Biochemistry and Ludwig-Maximilians-Universität, Am Klopferspitz 18, 82152 Martinsreid, Munich, Germany.
authors: Maximilian T
authors: MT
authors: Strauss
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.
authors: Florian
authors: F
authors: Schueder
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.|Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors: Jesper
authors: J
authors: Vinther
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Abhichart
authors: A
authors: Krissanaprasit
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Daniel
authors: D
authors: Gudnason
authors: Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors: Anton Allen Abbotsford
authors: AA
authors: Smith
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Ryosuke
authors: R
authors: Ogaki
authors: Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors: Alexander N
authors: AN
authors: Zelikin
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Flemming
authors: F
authors: Besenbacher
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Victoria
authors: V
authors: Birkedal
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.|Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Warren Alpert Building, Boston, Massachusetts 02115, USA.
authors: Peng
authors: P
authors: Yin
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.
authors: William M
authors: WM
authors: Shih
authors: Wyss Institute for Biologically Inspired Engineering, Harvard University, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.|Max Planck Institute of Biochemistry and Ludwig-Maximilians-Universität, Am Klopferspitz 18, 82152 Martinsreid, Munich, Germany.|Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Warren Alpert Building, Boston, Massachusetts 02115, USA.
authors: Ralf
authors: R
authors: Jungmann
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.
authors: Mingdong
authors: M
authors: Dong
authors: Centre for DNA Nanotechnology, Interdisciplinary Nanoscience Center, iNANO, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark.|Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
authors: Kurt V
authors: KV
authors: Gothelf
mesh_terms: D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000379:methods*; D053770:Nanowires / Q000737:chemistry / Q000648:ultrastructure; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D011145:Polyvinyls / Q000737:chemistry
chemical_list: D004277:DNA, Single-Stranded; D009841:Oligonucleotides; D011108:Polymers; D011145:Polyvinyls; D004247:DNA