title: Mitoprotective dietary approaches for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Caloric restriction, fasting, and ketogenic diets.
abstract: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome is an idiopathic illness characterized by debilitating fatigue and neuro-immune abnormalities. A growing body of evidence proposes mitochondrial dysfunction as a central perpetrator of the illness due to activation of immune-inflammatory pathways that burden the mitochondria. Under a model of mitochondrial dysfunction, this paper explores dietary strategies that are mitoprotective. Studied for decades, the cellular mechanisms of ketogenic diets, fasting, and caloric restriction now reveal mitochondria-specific mechanisms which could play a role in symptom reduction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Future research should examine the physiological effects of these dietary strategies in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
authors: Private Practice, Queens, NY, United States. Electronic address: info@drcourtneycraig.com.
authors: Courtney
authors: C
authors: Craig
mesh_terms: D031204:Caloric Restriction; D055423:Diet, Ketogenic; D019587:Dietary Supplements; D005215:Fasting; D015673:Fatigue Syndrome, Chronic / Q000178:diet therapy*; D006801:Humans