title: Vision Science: Can Rhodopsin Cure Blindness?
abstract: Outer retinal degeneration is the leading cause of blindness in the developed world. A new study now demonstrates that ectopic expression of human rhodopsin in the inner retina, mediated by viral gene therapy, can restore light sensitivity and some vision to mice blind from outer retinal degeneration.
authors: Department of Ophthalmology, University of Washington School of Medicine, Seattle, WA 98104, USA; Department of Biological Structure, University of Washington School of Medicine, Seattle, WA 98104, USA; Department of Pathology, University of Washington School of Medicine, Seattle, WA 98104, USA. Electronic address: russvg@uw.edu.
authors: Russell N
authors: RN
authors: Van Gelder
authors: Department of Ophthalmology, University of Washington School of Medicine, Seattle, WA 98104, USA.
authors: Kuldeep
authors: K
authors: Kaur
mesh_terms: D000818:Animals; D000066630:Ectopic Gene Expression; D006801:Humans; D012162:Retinal Degeneration / Q000628:therapy*; D012243:Rhodopsin / Q000235:genetics*
chemical_list: D012243:Rhodopsin