title: Several hundred-fold enhanced fluorescence from single fluorophores assembled on silver nanoparticle-dielectric-metal substrate.
abstract: We observed over 400-fold enhanced fluorescence from single Cy5 molecules assembled on multilayer silver nanoparticle-dielectric-metal (PDM) substrate. This substantial enhancement is due to the near-field enhanced excitation, emission, and interaction of Cy5 with plasmonic nanostructures. Experimental observation is supported by finite-element method calculations.
authors: Centre for Fluorescence Spectroscopy, University of Maryland School of Medicine, Department of Biochemistry and Molecular Biology, 725 West Lombard Street, Baltimore, MD 21201, USA. kray@som.umaryland.edu.
authors: Krishanu
authors: K
authors: Ray
authors: Ramachandram
authors: R
authors: Badugu
authors: Henryk
authors: H
authors: Szmacinski
authors: Joseph R
authors: JR
authors: Lakowicz
mesh_terms: D002232:Carbocyanines / Q000737:chemistry*; D005453:Fluorescence; D053768:Metal Nanoparticles / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D002232:Carbocyanines; C085321:cyanine dye 5; D012834:Silver