title: Transition Metal-Free Oxidative Radical Decarboxylation/Cyclization for the Construction of 6-Alkyl/Aryl Phenanthridines.
abstract: A radical cascade decarboxylation/cyclization of 2-isocyanobiphenyls with aliphatic carboxylic acids as well as aromatic carboxylic acids under the transition metal-free conditions was reported. This process, which included formation of two new C-C bonds and cleavage of C-COOH bonds, afforded a novel and environmentally friendly approach to producing 6-alkyl/aryl phenanthridines with moderate to good yields.
authors: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University , 38 Xueyuan Road, Beijing 100191, People's Republic of China.|National Institute of Biological Sciences (NIBS) , 7 Science Park Road, ZGC life science park, Beijing 102206, People's Republic of China.|Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , 2 Nanwei Road, Xicheng District, Beijing 100050, People's Republic of China.
authors: Shichao
authors: S
authors: Lu
authors: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , 2 Nanwei Road, Xicheng District, Beijing 100050, People's Republic of China.
authors: Yaling
authors: Y
authors: Gong
authors: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University , 38 Xueyuan Road, Beijing 100191, People's Republic of China.
authors: Demin
authors: D
authors: Zhou