title: Automated Glycan Assembly of Oligosaccharides Related to Arabinogalactan Proteins.
abstract: Arabinogalactan proteins are heavily glycosylated proteoglycans in plants. Their glycan portion consists of type-II arabinogalactan polysaccharides whose heterogeneity hampers the assignment of the arabinogalactan protein function. Synthetic chemistry is key to the procurement of molecular probes for plant biologists. Described is the automated glycan assembly of 14 oligosaccharides from four monosaccharide building blocks. These linear and branched glycans represent key structural features of natural type-II arabinogalactans and will serve as tools for arabinogalactan biology.
authors: Department of Biomolecular Systems, Max-Planck-Institute of Colloids and Interfaces , Am Mühlenberg 1, 14476 Potsdam, Germany.|Institute of Chemistry and Biochemistry, Freie Universität Berlin , Arnimallee 22, 14195 Berlin, Germany.
authors: Max P
authors: MP
authors: Bartetzko
authors: Department of Biomolecular Systems, Max-Planck-Institute of Colloids and Interfaces , Am Mühlenberg 1, 14476 Potsdam, Germany.|Institute of Chemistry and Biochemistry, Freie Universität Berlin , Arnimallee 22, 14195 Berlin, Germany.
authors: Frank
authors: F
authors: Schuhmacher
authors: Department of Biomolecular Systems, Max-Planck-Institute of Colloids and Interfaces , Am Mühlenberg 1, 14476 Potsdam, Germany.|Institute of Chemistry and Biochemistry, Freie Universität Berlin , Arnimallee 22, 14195 Berlin, Germany.
authors: Heung Sik
authors: HS
authors: Hahm
authors: Department of Biomolecular Systems, Max-Planck-Institute of Colloids and Interfaces , Am Mühlenberg 1, 14476 Potsdam, Germany.|Institute of Chemistry and Biochemistry, Freie Universität Berlin , Arnimallee 22, 14195 Berlin, Germany.
authors: Peter H
authors: PH
authors: Seeberger
authors: Department of Biomolecular Systems, Max-Planck-Institute of Colloids and Interfaces , Am Mühlenberg 1, 14476 Potsdam, Germany.|Institute of Chemistry and Biochemistry, Freie Universität Berlin , Arnimallee 22, 14195 Berlin, Germany.
authors: Fabian
authors: F
authors: Pfrengle
mesh_terms: D005685:Galactans / Q000737:chemistry; D006031:Glycosylation; D015394:Molecular Structure; D009088:Mucoproteins / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D010940:Plant Proteins / Q000737:chemistry; D011134:Polysaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D011506:Proteins / Q000378:metabolism*; D011509:Proteoglycans
chemical_list: D005685:Galactans; D009088:Mucoproteins; D009844:Oligosaccharides; D010940:Plant Proteins; D011134:Polysaccharides; D011506:Proteins; D011509:Proteoglycans; C006619:arabinogalactan proteins; C005653:arabinogalactan