title: Central-Variant Posterior Reversible Encephalopathy due to Sulfasalazine: A Case Report.
abstract: OBJECTIVE
  To report a rare case with central-variant posterior reversible encephalopathy syndrome due to sulfasalazine.
  
  
  METHODS
  A 55-year-old female patient presented with seizure and acute-onset hemiparesia. Thirty days earlier, treatment with sulfasalazine was commenced in response to a diagnosis of psoriatic arthritis. Laboratory examinations were normal. Brain magnetic resonance imaging showed symmetric edema within basal ganglia and thalami with sparing of the cerebral cortices. After stopping the treatment of sulfasalazine, clinical and radiological findings regressed dramatically.
  
  
  CONCLUSIONS
  This was a case of central-variant posterior reversible encephalopathy syndrome due to sulfasalazine, and atypical imaging findings should be kept in mind for early diagnosis.
authors: Clinic of Neurology, Tepecik Education and Research Hospital, Izmir, Turkey.
authors: Levent
authors: L
authors: Ocek
authors: Ufuk
authors: U
authors: Sener
authors: Burcu S
authors: BS
authors: Demirtas
authors: Metin M
authors: MM
authors: Ozcelik
authors: Ozgur
authors: O
authors: Oztekin
authors: Yasar
authors: Y
authors: Zorlu
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D015535:Arthritis, Psoriatic / Q000188:drug therapy; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D054038:Posterior Leukoencephalopathy Syndrome / Q000139:chemically induced*; D012640:Seizures / Q000139:chemically induced; D012460:Sulfasalazine / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D018501:Antirheumatic Agents; D012460:Sulfasalazine