title: (Bi)Weekly folic acid supplementation might be inferior to a daily folic acid dosing schedule in the prevention of methotrexate-related toxicity in patients with rheumatoid arthritis.
authors: Department of Pharmacy, Sint Maartenskliniek, Nijmegen; and Department of Pharmacy, Radboud University Medical Center, Nijmegen, The Netherlands.
authors: Bartholomeus J F
authors: BJ
authors: van den Bemt
authors: Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands.
authors: Alfons A
authors: AA
authors: den Broeder
authors: Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
authors: Marielle
authors: M
authors: Van der Burgt
authors: Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
authors: Jaap
authors: J
authors: Fransen
authors: Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
authors: Annelies E
authors: AE
authors: van Ede
authors: Department of Rheumatology, Sint Maartenskliniek, Nijmegen; and Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.
authors: Frank H J
authors: FH
authors: van den Hoogen
mesh_terms: D018501:Antirheumatic Agents / Q000008:administration & dosage*; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000188:drug therapy*; D019587:Dietary Supplements; D004334:Drug Administration Schedule; D064420:Drug-Related Side Effects and Adverse Reactions / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D005492:Folic Acid / Q000008:administration & dosage*; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects*; D020011:Protective Agents / Q000008:administration & dosage*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D018501:Antirheumatic Agents; D020011:Protective Agents; D005492:Folic Acid; D008727:Methotrexate