title: Micro-thermography in millimeter-scale animals by using orally-dosed fluorescent nanoparticle thermosensors.
abstract: We propose an instant micro-thermography method using a fluorescent-nanoparticle thermosensor capable of reporting temperature as the fluorescence intensity ratio of the temperature-sensitive dye to the reference. We demonstrate "temperature mapping" inside a fruit fly larva that was orally dosed with nanoparticle thermosensors.
authors: Waseda Bioscience Research Institute in Singapore (WABIOS), Singapore. suzu_mado@aoni.waseda.jp.
authors: Satoshi
authors: S
authors: Arai
authors: School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore. hirosato@ntu.edu.sg.
authors: Ferdinandus
authors: Waseda Bioscience Research Institute in Singapore (WABIOS), Singapore. suzu_mado@aoni.waseda.jp and Department of Life Science & Medical Bioscience, Faculty of Science & Engineering, Waseda University, Japan.
authors: Shinji
authors: S
authors: Takeoka
authors: Waseda Bioscience Research Institute in Singapore (WABIOS), Singapore. suzu_mado@aoni.waseda.jp and Organization for University Research Initiatives, Waseda University, Japan.
authors: Shin'ichi
authors: S
authors: Ishiwata
authors: School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore. hirosato@ntu.edu.sg.
authors: Hirotaka
authors: H
authors: Sato
authors: Waseda Bioscience Research Institute in Singapore (WABIOS), Singapore. suzu_mado@aoni.waseda.jp and Organization for University Research Initiatives, Waseda University, Japan.
authors: Madoka
authors: M
authors: Suzuki
mesh_terms: D000818:Animals; D001831:Body Temperature; D004330:Drosophila / Q000502:physiology*; D005456:Fluorescent Dyes / Q000032:analysis*; D007814:Larva / Q000502:physiology; D053758:Nanoparticles / Q000032:analysis*; D061848:Optical Imaging / Q000379:methods; D013817:Thermography / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes