title: What Are the Predictive Factors for Gleason Score Upgrade following RP?
abstract: The Gleason score is one of a number of factors used in staging patients diagnosed with prostate cancer and in determining the treatment path such patients will ultimately follow. However, discrepancies in the Gleason scores obtained through biopsy compared with the final pathological staging of specimens following radical prostatectomy are not uncommon. Incorrect Gleason scoring can potentially influence treatment decisions and therefore, it is imperative that research is undertaken to elucidate factors that may be able to predict whether a patient's Gleason score might need to be reconsidered. A literature review was undertaken in late 2014 to highlight some of these factors that require further investigation.
authors: University of Melbourne, Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Vict., Australia.
authors: David Rhys
authors: DR
authors: Alchin
authors: Declan
authors: D
authors: Murphy
authors: Nathan
authors: N
authors: Lawrentschuk
mesh_terms: D000368:Aged; D001706:Biopsy / Q000379:methods*; D003951:Diagnostic Errors / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading / Q000592:standards*; D015995:Prevalence; D011379:Prognosis; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D012008:Recurrence; D012307:Risk Factors
chemical_list: D017430:Prostate-Specific Antigen