title: Castor Oil-Based Biodegradable Polyesters.
abstract: This Review compiles the synthesis, physical properties, and biomedical applications for the polyesters based on castor oil and ricinoleic acid. Castor oil has been known for its medicinal value since ancient times. It contains ∼90% ricinoleic acid, which enables direct chemical transformation into polyesters without interference of other fatty acids. The presence of ricinoleic acid (hydroxyl containing fatty acid) enables synthesis of various polyester/anhydrides. In addition, castor oil contains a cis-double bond that can be hydrogenated, oxidized, halogenated, and polymerized. Castor oil is obtained pure in large quantities from natural sources; it is safe and biocompatible.
authors: Department of Medicinal Chemistry and Natural Products, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem , Jerusalem 91120, Israel.
authors: Konda Reddy
authors: KR
authors: Kunduru
authors: Department of Medicinal Chemistry and Natural Products, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem , Jerusalem 91120, Israel.
authors: Arijit
authors: A
authors: Basu
authors: Department of Medicinal Chemistry and Natural Products, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem , Jerusalem 91120, Israel.
authors: Moran
authors: M
authors: Haim Zada
authors: Department of Medicinal Chemistry and Natural Products, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem , Jerusalem 91120, Israel.
authors: Abraham J
authors: AJ
authors: Domb
mesh_terms: D000812:Anhydrides / Q000138:chemical synthesis / Q000737:chemistry; D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry; D006801:Humans; D011091:Polyesters / Q000138:chemical synthesis / Q000737:chemistry; D012277:Ricinoleic Acids / Q000737:chemistry*
chemical_list: D000812:Anhydrides; D001672:Biocompatible Materials; D011091:Polyesters; D012277:Ricinoleic Acids