title: [Review of the novelties from the 2014 ECTRIMS-ACTRIMS Joint Congress, presented at the 7th Post-ECTRIMS meeting (I)].
abstract: For the seventh year in a row the Post-ECTRIMS Meeting has been held in Madrid (Spain). Renowned specialists in multiple sclerosis and national leaders in this area have gathered once again to discuss the novelties presented at the 2014 ECTRIM-ACTRIMS World Congress. That meeting gave rise to this review, which will be published in two parts. One of the main conclusions in this first part is the deeper understanding of the genetic component of multiple sclerosis that we are acquiring, although it is still insufficient unless we bear in mind its interaction with the environmental risk factors of the disease or the impact of comorbidity and healthy habits on the patients' susceptibility and prognosis. In this respect, the authors insist on the fact that, in clinical practice, the cognitive and psychiatric disorders remain under-diagnosed and are rarely taken into account in clinical research. Yet, although scarce, the evidence we have points to the possible benefits of disease-modifying drugs and alternatives to treatment with selective serotonin reuptake inhibitors. Addressing the sub-populations in multiple sclerosis and variants of the disease enhances the importance of an early accurate diagnosis in order to offer patients a safer and more personalised prognosis and treatment. Paediatric multiple sclerosis is ideal for studying the risk factors of the disease but, given its low prevalence, the use of prospective studies raises a number of doubts and there is a preference for conducting collaborative studies.
authors: Fundacion IMABIS, Hospital Universitario Carlos Haya, 29190 Malaga, Espana.
authors: O
authors: O
authors: Fernandez
authors: J C
authors: JC
authors: Alvarez-Cermeno
authors: R
authors: R
authors: Arroyo
authors: Ll
authors: L
authors: Brieva
authors: M C
authors: MC
authors: Calles-Hernandez
authors: B
authors: B
authors: Casanova-Estruch
authors: M
authors: M
authors: Comabella
authors: J A
authors: JA
authors: Garcia-Merino
authors: R
authors: R
authors: Ginestal
authors: G
authors: G
authors: Izquierdo
authors: J E
authors: JE
authors: Meca-Lallana
authors: M M
authors: MM
authors: Mendibe-Bilbao
authors: X
authors: X
authors: Montalban
authors: D
authors: D
authors: Munoz-Garcia
authors: J
authors: J
authors: Olascoaga
authors: P
authors: P
authors: Oliva-Nacarino
authors: C
authors: C
authors: Oreja-Guevara
authors: Ll
authors: L
authors: Ramio-Torrenta
authors: L
authors: L
authors: Romero-Pinel
authors: A
authors: A
authors: Rodriguez-Antiguedad
authors: A
authors: A
authors: Saiz
authors: M
authors: M
authors: Tintore
authors: Grupo Post-Ectrims
authors: GP
authors: Grupo Post-Ectrims
mesh_terms: D003226:Congresses as Topic; D006801:Humans; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000628:therapy