title: Auer Rod-Like Inclusions in Prolymphocytic Leukemia.
abstract: BACKGROUND
  Prolymphocytic leukemia (PLL) is a generalized malignancy of the lymphoid tissue, usually of B cell type. Auer rod-like inclusions in prolymphocytic leukemia cells are an extremely rare event; the inclusions are very similar to the Auer rods morphologically.
  
  
  METHODS
  We describe a case of B-cell PLL presenting with Auer rod-like inclusions. The diagnosis was eventually proven by the morphology, cytochemical staining, immunophenotypes, and electron microscopy.
  
  
  RESULTS
  Auer rod-like inclusions are pathological changes of mitochondria with increasing density of matrix and disappearing internal instructure seen through a scanning electronic microscope.
  
  
  CONCLUSIONS
  Auer rod-like inclusions can present in pathologically changed prolymphocytic leukemia cells.
authors: Zhou
authors: Z
authors: Qiufan
authors: Xu
authors: X
authors: Shumei
authors: Dong
authors: D
authors: Xifeng
authors: Dong
authors: D
authors: Shuwen
authors: Wang
authors: W
authors: Huaquan
authors: Shao
authors: S
authors: Zonghong
mesh_terms: D001402:B-Lymphocytes / Q000276:immunology / Q000648:ultrastructure*; D014408:Biomarkers, Tumor / Q000032:analysis; D001856:Bone Marrow Examination; D006801:Humans; D016130:Immunophenotyping; D054403:Leukemia, Prolymphocytic, B-Cell / Q000276:immunology / Q000473:pathology*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D008928:Mitochondria / Q000276:immunology / Q000648:ultrastructure*; D011237:Predictive Value of Tests
chemical_list: D014408:Biomarkers, Tumor