title: Electrospray mass spectrometry with controlled in-source atomization (ERIAD) as a promising elemental method: evaluation of analytical features.
abstract: Electrospray ionization with controlled in-source fragmentation and atomization (ERIAD) is promising method for mass-spectrometric elemental analysis. This paper concerns the main analytical features and necessary instrumentation for ERIAD. The method is shown to be effective for more than 70 elements of the periodic table: those that present as cations in a water solution. It shows a high absolute sensitivity with a low spread from Li to U, and a detection limit of tens of parts per trillion. The soft ionization used results in the absence of plasma chemical reaction products, typical for inductively coupled plasma mass spectrometry, and the spectra are nearly free from interferences. The method does not require a high resolution and can be used for samples with an artificial isotopic content. The method is essentially valid for radiochemistry and metallomics, as it has the possibility to combine measurements of chemical, elemental, and even isotopic content simultaneously.
authors: Institute for Analytical Instrumentation of RAS, Rizsky pr., 26, St.Petersburg, 190103 Russia. lngall@narod.ru.
authors: L N
authors: LN
authors: Gall
authors: Ioffe Physico-Technical Institute of RAS, Politechnicheskaya, 26, St.Petersburg, 194021, Russia. kolomna88@mail.ru.
authors: N S
authors: NS
authors: Fomina
authors: Shimadzu research laboratory Europe, Trafford Wharf Road, Stretford M17 1GP, Manchester, England.. roger.giles@srlab.co.uk.
authors: R
authors: R
authors: Giles
authors: Institute for Analytical Instrumentation of RAS, Rizsky pr., 26, St.Petersburg, 190103 Russia. Ioffe Physico-Technical Institute of RAS, Politechnicheskaya, 26, St.Petersburg, 194021, Russia. serg_08@mail.ru.
authors: S V
authors: SV
authors: Masukevich
authors: TECHNAN Ltd, St.Petersburg, Zeleznovodskaya, 17/5, 199155, Russia.. belolesya@yandex.ru.
authors: O A
authors: OA
authors: Beliaeva
authors: Institute for Analytical Instrumentation of RAS, Rizsky pr., 26, St.Petersburg, 190103 Russia. Ioffe Physico-Technical Institute of RAS, Politechnicheskaya, 26, St.Petersburg, 194021, Russia. Saint-Petersburg State Polytechnical University, Politechnicheskaya, 29, St.Petersburg, Russia.. gall@ms.ioffe.ru.
authors: N R
authors: NR
authors: Gall