title: [Current concepts on hemodynamic support and therapy in septic shock].
abstract: Severe sepsis and septic shock represent a major healthcare challenge. Much of the improvement in mortality associated with septic shock is related to early recognition combined with timely fluid resuscitation and adequate antibiotics administration. The main goals of septic shock resuscitation include intravascular replenishment, maintenance of adequate perfusion pressure and oxygen delivery to tissues. To achieve those goals, fluid responsiveness evaluation and complementary interventions - i.e. vasopressors, inotropes and blood transfusion - may be necessary. This article is a literature review of the available evidence on the initial hemodynamic support of the septic shock patients presenting to the emergency room or to the intensive care unit and the main interventions available to reach those targets, focusing on fluid and vasopressor therapy, blood transfusion and inotrope administration.
authors: Unidade de Terapia Intensiva, Hospital Israelita Albert Einstein, São Paulo, SP, Brasil.
authors: Leonardo Lima
authors: LL
authors: Rocha
authors: Unidade de Terapia Intensiva, Hospital Israelita Albert Einstein, São Paulo, SP, Brasil.
authors: Camila Menezes Souza
authors: CM
authors: Pessoa
authors: Unidade de Terapia Intensiva, Hospital Israelita Albert Einstein, São Paulo, SP, Brasil.
authors: Thiago Domingos
authors: TD
authors: Corrêa
authors: Unidade de Terapia Intensiva, Hospital Israelita Albert Einstein, São Paulo, SP, Brasil.
authors: Adriano José
authors: AJ
authors: Pereira
authors: Unidade de Terapia Intensiva, Hospital Israelita Albert Einstein, São Paulo, SP, Brasil.
authors: Murillo Santucci Cesar
authors: MS
authors: de Assunção
authors: Unidade de Terapia Intensiva, Hospital Israelita Albert Einstein, São Paulo, SP, Brasil. Electronic address: silva.eliezer@einstein.br.
authors: Eliézer
authors: E
authors: Silva
keywords: Agentes vasoconstritores; Choque séptico; Fluid therapy; Fluidoterapia; Hemodinâmica; Hemodynamics; Reposição volêmica; Resuscitation; Septic shock; Vasoconstrictor agents