title: The Triglyceride Paradox in Stroke Survivors: A Prospective Study.
abstract: Objective. The purpose of our study was to understand the association between serum triglycerides and outcomes in acute ischemic stroke (AIS) patients. Methods. A cohort of all adult patients presenting to the Emergency Department (ED) with an AIS from March 2004 to December 2005 were selected. The lipid profile levels were measured within 24 hours of stroke onset. Demographics, admission stroke severity (NIHSS), functional outcome at discharge (modified Rankin Scale (mRS)), and mortality at 3 months were recorded. Results. The final cohort consisted of 334 subjects. A lower level of triglycerides at presentation was found to be significantly associated with worse National Institutes of Health Stroke Scale (NIHSS) (P = 0.004), worse mRS (P = 0.02), and death at 3 months (P = 0.0035). After adjusting for age and gender and NIHSS, the association between triglyceride and mortality at 3 months was not significant (P = 0.26). Conclusion. Lower triglyceride levels seem to be associated with a worse prognosis in AIS.
authors: Department of Neurosurgery, University of Rochester Medical Center, Rochester, NY 14627, USA.
authors: Minal
authors: M
authors: Jain
authors: Department of Neurosurgery, University of Rochester Medical Center, Rochester, NY 14627, USA.
authors: Anunaya
authors: A
authors: Jain
authors: Department of Emergency Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
authors: Neeraja
authors: N
authors: Yerragondu
authors: Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
authors: Robert D
authors: RD
authors: Brown
authors: Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
authors: Alejandro
authors: A
authors: Rabinstein
authors: Department of Neurosurgery, University of Rochester Medical Center, Rochester, NY 14627, USA.
authors: Babak S
authors: BS
authors: Jahromi
authors: Department of Emergency Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
authors: Lekshmi
authors: L
authors: Vaidyanathan
authors: Department of Emergency Medicine, University of Rochester Medical Center, Rochester, NY 14627, USA.
authors: Brian
authors: B
authors: Blyth
authors: Department of Emergency Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA ; Departments of Emergency Medicine and Neurological Surgery, University of Florida College of Medicine, Gainesville, FL 32608, USA.
authors: Latha Ganti
authors: LG
authors: Stead