title: Uveitis in juvenile idiopathic arthritis: recent therapeutic advances.
abstract: Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment. Since corticosteroid treatment is not a preferred long-term option for most patients with this condition, systemic immunosuppressive therapy is frequently employed. The medical options for the treatment of JIA-associated uveitis have recently expanded beyond conventional immunosuppressive drugs to the biological agents. The biological drugs that are most commonly employed for JIA-associated uveitis are the tumor necrosis factor-α inhibitors. Other biological agents that have been used to treat the disease include drugs that target cytokine receptors, lymphocyte antigens and lymphocyte co-stimulation signals. This Mini Review highlights recent developments in the medical treatment of JIA-associated uveitis.
authors: Eye and Vision Health, Flinders University School of Medicine, Adelaide, S.A., Australia.
authors: Jane M
authors: JM
authors: Wells
authors: Justine R
authors: JR
authors: Smith
mesh_terms: D001171:Arthritis, Juvenile / Q000150:complications*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D014605:Uveitis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D007166:Immunosuppressive Agents