title: Enzyme transition states from theory and experiment.
authors: Integration of kinetic isotope effect analyses to elucidate ribonuclease mechanism.
authors: Mike E
authors: ME
authors: Harris
authors: Heavy atom labeled nucleotides for measurement of kinetic isotope effects.
authors: Joseph A
authors: JA
authors: Piccirilli
authors: Effect of Zn(2+) binding and enzyme active site on the transition state for RNA 2'-O-transphosphorylation interpreted through kinetic isotope effects.
authors: Darrin M
authors: DM
authors: York
mesh_terms: D000465:Algorithms; D055162:Biocatalysis; D020134:Catalytic Domain; D004798:Enzymes / Q000737:chemistry* / Q000378:metabolism; D007554:Isotopes / Q000737:chemistry; D007700:Kinetics; D008956:Models, Chemical; D008958:Models, Molecular; D013379:Substrate Specificity
chemical_list: D004798:Enzymes; D007554:Isotopes