title: Radiation induced liver disease: A clinical update.
abstract: Radiation-induced liver disease (RILD) or radiation hepatitis is a sub-acute form of liver injury due to radiation. It is one of the most dreaded complications of radiation which prevents radiation dose escalation and re-irradiation for hepatobiliary or upper gastrointestinal malignancies. This complication should be kept in mind whenever a patient is planned for irradiation of these malignancies. Although, incidence of RILD is decreasing due to better knowledge of liver tolerance, improved investigation modalities and modern radiation delivery techniques, treatment options are still limited. In this review article, we have focussed on patho-physiology, risk factors, prevention and management of RILD.
authors: Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi 110029, India.
authors: R
authors: R
authors: Benson
authors: Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi 110029, India. Electronic address: renumadan10@yahoo.com.
authors: R
authors: R
authors: Madan
authors: Department of Gastrointestinal Surgery and Liver Transplant, All India Institute of Medical Sciences, New Delhi 110029, India.
authors: R
authors: R
authors: Kilambi
authors: Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi 110029, India.
authors: S
authors: S
authors: Chander
mesh_terms: D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D011832:Radiation Injuries / Q000175:diagnosis* / Q000517:prevention & control / Q000628:therapy*; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D012307:Risk Factors
keywords: Management; Patho-physiology; Radiation induced liver disease; Risk factors