title: Suicide risk in patients with migraine and  comorbid fibromyalgia.
abstract: OBJECTIVE
  To identify the frequency, clinical effects, and suicide risk in comorbid fibromyalgia(FM) among patients with migraine.
  
  
  METHODS
  We surveyed patients with migraine who attended a headache clinic. All patients completed questionnaires containing demographics, headache profiles based on the International Classification of Headache Disorders, 2nd edition, FM questionnaires based on the modified 2010 American College of Rheumatology preliminary diagnostic criteria, Migraine Disability Assessment, Hospital Anxiety and Depression Scale, and Pittsburgh Sleep Quality Index. Suicide risk was evaluated by self-report of lifetime suicidal ideation and attempts.
  
  
  RESULTS
  Of the 1,318 recruited patients with migraine (aged 42.6 ± 12.7 years; female/male = 4.5), 10.1% (aged 44.3 ± 12.6 years; female/male = 7.9) had comorbidity of FM. Patients with migraine and comorbid FM had higher headache frequency and headache-related disability, poor sleep quality, and were more depressed/anxious than those with migraine only (p < 0.001). Suicidal ideation and attempts were reported in 27.3% and 6.9% of patients with migraine, respectively, and were higher in patients with comorbid FM than in those without (ideation: 58.3% vs 24%; attempt: 17.6% vs 5.7%; p < 0.001). In addition, comorbidity of FM was associated with a higher suicide risk in 3 different migraine subgroups, i.e., migraine without aura, migraine with aura, and chronic migraine. After controlling for covariates, comorbidity of FM remained as a predictor of suicidal ideation and attempts (odds ratio 2.61 and 1.99, respectively, p < 0.05)in patients with migraine.
  
  
  CONCLUSIONS
  Comorbidity with FM is associated with a high suicide risk in patients with migraine.
authors: Hung-Yu
authors: HY
authors: Liu
authors: Jong-Ling
authors: JL
authors: Fuh
authors: Yung-Yang
authors: YY
authors: Lin
authors: Wei-Ta
authors: WT
authors: Chen
authors: Shuu-Jiun
authors: SJ
authors: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D005356:Fibromyalgia / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000175:diagnosis* / Q000453:epidemiology* / Q000523:psychology; D011446:Prospective Studies; D012307:Risk Factors; D059020:Suicidal Ideation; D013406:Suicide, Attempted / Q000523:psychology; D011795:Surveys and Questionnaires; D055815:Young Adult