title: Cardiac resynchronization therapy is appropriate for all patients requiring chronic right ventricular pacing: the pro perspective.
abstract: Long-term right ventricular pacing has deleterious effects on the left ventricle (LV). The risk of pacemaker-induced cardiomyopathy (PICM) seems to be lower in patients with a normal LV ejection fraction (LVEF). Patients developing PICM respond favorably to a cardiac resynchronization therapy upgrade, suggesting that the dysfunction is partially reversible. Biventricular pacing has emerged as a treatment and/or prevention of PICM. Cumulative pacing greater than 40% of the time is considered the most important risk factor for PICM. No organizational guidelines exist for preventive biventricular pacing. The decision to pursue biventricular pacing should be individualized.
authors: Electrophysiology and Arrhythmia Services, Department of Cardiovascular Disease, Tampa General Hospital, University of South Florida Morsani College of Medicine, South Tampa Campus (5th Floor), Two Tampa General Circle, Tampa, FL 33606, USA. Electronic address: Bherweg@health.usf.edu.
authors: Bengt
authors: B
authors: Herweg
authors: Department of Cardiovascular Disease, Tampa General Hospital, University of South Florida Morsani College of Medicine, South Tampa Campus (5th Floor), Two Tampa General Circle, Tampa, FL 33606, USA.
authors: Robin
authors: R
authors: Singh
authors: Clinical Cardiac Electrophysiology, Department of Cardiovascular Disease, University of Rochester Medical Center, 2613 W Henrietta Road, Rochester, NY 14623, USA.
authors: S Serge
authors: SS
authors: Barold
mesh_terms: D058406:Cardiac Resynchronization Therapy / Q000009:adverse effects* / Q000379:methods*; D009202:Cardiomyopathies / Q000453:epidemiology / Q000209:etiology; D006333:Heart Failure / Q000628:therapy*; D006801:Humans; D010138:Pacemaker, Artificial / Q000009:adverse effects*
keywords: Biventricular pacing; Cardiac pacing; Cardiac resynchronization; Cardiomyopathy; Heart failure