title: Severe intravenous immunoglobulin-induced hemolysis with pigment nephropathy managed with red cell exchange.
abstract: We report on the use of red cell exchange in a case of severe intravenous immune globulin induced hemolysis and pigment nephropathy. Renal impairment and hemoglobinuria were not ameliorated by supportive measures including hydration. Partial red cell exchange with group O blood reduced hemoglobinuria and appeared to stabilize renal function. This is the first report on the use of red cell exchange in this clinical setting. J. Clin. Apheresis 31:464-466, 2016. © 2015 Wiley Periodicals, Inc.
authors: Clinical Haematology Department, Austin Health, Victoria, Australia.
authors: Masa
authors: M
authors: Lasica
authors: Clinical Haematology Department, Austin Health, Victoria, Australia. daniela.zantomio@austin.org.au.
authors: Daniela
authors: D
authors: Zantomio
mesh_terms: D000017:ABO Blood-Group System; D016238:Cytapheresis; D017707:Erythrocyte Transfusion; D006456:Hemoglobinuria / Q000628:therapy; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects*; D007674:Kidney Diseases / Q000139:chemically induced / Q000628:therapy*; D008297:Male; D008875:Middle Aged
chemical_list: D000017:ABO Blood-Group System; D016756:Immunoglobulins, Intravenous
keywords: ABO hemagglutinins; acute renal failure; intravenous immune globulin (IVIg)