title: Evaluation of antimicrobial susceptibility of Escherichia coli strains isolated in Rabat University Hospital (Morocco).
abstract: BACKGROUND
  Escherichia coli (E. coli) is the most commonly isolated bacteria in human pathology. In Morocco the data concerning the nature and the rates of antibiotic resistance of E. coli in both hospitals and city environment remains relatively poor and needs further investigations.
  
  
  METHODS
  During a 16 months period, E. coli isolates were collected from different culture specimens received in the Bacteriology Department of the Military teaching Hospital Mohammed-V-Rabat for routine diagnostic purposes. E. coli isolates were identified and their antimicrobial susceptibility pattern was determined.
  
  
  RESULTS
  A total of 1369 E. coli isolates comprising 33% (1369/4110) of culture-positive samples were consecutively collected. Isolates of E. coli were, in 40.5% (554/1369) of cases from hospitalized patients and in 59.5% (815/1369) of cases from outpatients. Urine isolates represented 82% (1123/1369) of the cases. High rates of resistance were found for amoxicillin (42.5%), cefalotin (30.4%), norfoloxacin (29.9%) and sulfamethoxazole (37.7%). The detection rate of ESBL was 6.1% (85/1369). In hospitalized patients 11.9% of the isolates of E. coli (66/554) had an ESBL phenotype while in outpatients cases only 2.3% of isolates of E. coli (19/815) had this phenotype.
  
  
  CONCLUSIONS
  Our findings suggest that more judicious use of antibiotics is needed especially in probabilistic treatment. The emergence of ESBL in the Moroccan cities is an indicator of the severity of this problem that is not limited to health care facilities.
authors: Hôpital Militaire d'Instruction Mohammed V, Rabat, Morocco. nabil_alem86@hotmail.fr.|Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. nabil_alem86@hotmail.fr.|, villa 96 la corniche hay el fath, Rabat, Morocco. nabil_alem86@hotmail.fr.
authors: Nabil
authors: N
authors: Alem
authors: Hôpital Militaire d'Instruction Mohammed V, Rabat, Morocco. Frikmed@yahoo.fr.|Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. Frikmed@yahoo.fr.
authors: Mohammed
authors: M
authors: Frikh
authors: Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. a.srifi@gmail.com.
authors: Abdellatif
authors: A
authors: Srifi
authors: Faculté de Médecine de Pharmacie d'Oujda Université Mohammed I, Oujda, Morocco. maleb.adil@hotmail.com.
authors: Adil
authors: A
authors: Maleb
authors: Hôpital Militaire d'Instruction Mohammed V, Rabat, Morocco. mariamachadli@gmail.com.|Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. mariamachadli@gmail.com.
authors: Mariama
authors: M
authors: Chadli
authors: Hôpital Militaire d'Instruction Mohammed V, Rabat, Morocco. yassinesekhsokh@gmail.com.|Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. yassinesekhsokh@gmail.com.
authors: Yassine
authors: Y
authors: Sekhsokh
authors: Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. lhoulouzi@yahoo.fr.
authors: Lhoucin
authors: L
authors: Louzi
authors: Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. a.ibrahimi@um5s.net.ma.
authors: Azzedine
authors: A
authors: Ibrahimi
authors: Hôpital Militaire d'Instruction Mohammed V, Rabat, Morocco. lemnouera@yahoo.fr.|Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. lemnouera@yahoo.fr.
authors: Abdelhay
authors: A
authors: Lemnouer
authors: Hôpital Militaire d'Instruction Mohammed V, Rabat, Morocco. elouennassm@yahoo.fr.|Faculté de Médicine et de Pharmacie de Rabat Université Mohammed V Souissi, Rabat, Morocco. elouennassm@yahoo.fr.
authors: Mostafa
authors: M
authors: Elouennass
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D009018:Morocco
chemical_list: D000900:Anti-Bacterial Agents