title: Low Cardiorespiratory Fitness is Partially Linked to Ventilatory Factors in Obese Adolescents.
abstract: OBJECTIVE
  To examine the role of ventilatory constraint on cardiorespiratory fitness in obese adolescents.
  
  
  METHODS
  Thirty obese adolescents performed a maximal incremental cycling exercise and were divided into 2 groups based on maximal oxygen uptake (VO2peak): those presenting low (L; n = 15; VO2peak: 72.9 ± 8.6% predicted) or normal (N; n = 15; VO2peak: 113.6 ± 19.2% predicted) cardiorespiratory fitness. Both were compared with a group of healthy controls (C; n = 20; VO2peak: 103.1 ± 11.2% predicted). Ventilatory responses were explored using the flow volume loop method.
  
  
  RESULTS
  Cardiorespiratory fitness (VO2peak, in % predicted) was lower in L compared with C and N and was moderately associated with the percent predicted forced vital capacity (FVC) (r = .52; p < .05) in L. At peak exercise, end inspiratory point was lower in L compared with N and C (77.4 ± 8.1, 86.4 ± 7.7, and 89.9 ± 7.6% FVC in L, N, and C, respectively; p < .05), suggesting an increased risk of ventilatory constraint in L, although at peak exercise this difference could be attributed to the lower maximal ventilation in L.
  
  
  CONCLUSIONS
  Forced vital capacity and ventilatory strategy to incremental exercise slightly differed between N and L. These results suggest a modest participation of ventilatory factors to exercise intolerance.
authors: Univ. Grenoble Alpes, HP2, F-38000, Grenoble, France.
authors: Monique
authors: M
authors: Mendelson
authors: Anne-Sophie
authors: AS
authors: Michallet
authors: Julia
authors: J
authors: Tonini
authors: Anne
authors: A
authors: Favre-Juvin
authors: Michel
authors: M
authors: Guinot
authors: Bernard
authors: B
authors: Wuyam
authors: Patrice
authors: P
authors: Flore
mesh_terms: D000293:Adolescent; D000067697:Adolescent Health; D000072599:Cardiorespiratory Fitness; D016022:Case-Control Studies; D005080:Exercise Test; D017079:Exercise Tolerance; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D063766:Pediatric Obesity / Q000503:physiopathology*; D012123:Pulmonary Ventilation; D012129:Respiratory Function Tests; D012131:Respiratory Insufficiency / Q000503:physiopathology