title: Leiomyoma of the third eyelid in a dog.
abstract: A 14-year-old neutered male Dachshund presented for the evaluation of oculus dexter (OD) third eyelid elevation ongoing for approximately 2 months. Complete ophthalmic examination revealed a large, nonpainful, well-demarcated, soft mass at the base of the right third eyelid causing elevation and mild hyperemia. The mass was freely moveable with the third eyelid, and no right globe deviation was noted. No other abnormalities were noted on physical examination, routine blood chemistry, complete blood count, serum T4, urinalysis, or urine cortisol/creatinine ratio. Ocular B-mode ultrasonography showed an anechoic, well-demarcated, homogenous, soft tissue mass at the base of the third eyelid with no orbital extension. A leiomyoma was diagnosed after multiple punch biopsies were obtained from the palpebral surface of the mass. The right third eyelid was excised surgically. Histopathology confirmed a completely excised, nodular, unencapsulated, expansile mass within the third eyelid. Positive smooth muscle actin and negative S-100 immunohistochemistry confirmed a leiomyoma. Bundles of normal smooth muscle were also present adjacent to the mass. The mass was compressing the adjacent lacrimal gland and associated with moderate dacryoadenitis. Twelve months postoperatively, the right globe position and motility remain normal with no evidence of mass regrowth. To the author's knowledge, this is the first reported case of a leiomyoma of the third eyelid in any species. In this case, the mass was completely excised and no regrowth has occurred twelve months after surgery. This case along with independently reviewed canine third eyelids clearly demonstrates the presence of smooth muscle within the canine third eyelid.
authors: MedVet Medical and Cancer Centers for Pets, Cincinnati, OH, USA.
authors: Rachel L
authors: RL
authors: Mathes
authors: Portland Veterinary Specialists, Portland, ME, USA.
authors: Sarah J
authors: SJ
authors: Noble
authors: College of Veterinary Medicine, Athens Veterinary Diagnostic Laboratory, University of Georgia, Athens, GA, USA.
authors: Angela E
authors: AE
authors: Ellis
keywords: canine; eyelid leiomyoma; leiomyoma; smooth muscle; third eyelid