title: [Anatomoclinical study of ovarian cancers in patients with history of hysterectomy for benign pathology].
abstract: OBJECTIVE
  To establish the various anatomoclinical characteristics of ovarian cancer in patients with a history of hysterectomy for benign disease.
  
  
  METHODS
  This is a comparative, retrospective, monocentric and descriptive study, carried out at the Centre of Jean-Perrin in patients with ovarian cancer between 2005 and 2014 and with a history of hysterectomy for benign disease. Each patient was paired with a non-hysterectomy patient with ovarian cancer. The two populations were matched 1 to 5, based on their age at diagnosis and their FIGO stage.
  
  
  RESULTS
  During the period of the study, 249 patients were operated for de novo ovarian neoplasia, 43 patients had a history of hysterectomy (group 1) and 206 remaining patients represented the control group (group 2). There was no difference in overall survival and disease-free survival between the two subpopulations of patients (P=0.59 and P=0.38). On CT-scan assessment, the lymph node involvement risk was greater than 2.6 in the group of patients with hysterectomy (P=0.00038). Peritoneal Cancer Index scores of the two subgroups of populations were comparable, there were an average of 13.65 for group 1 versus 12.31 for group 2 (P=0.28). The rate of rectosigmoid resection was higher in group 1: 48.6% versus 32.9% in group 2 without any significant difference (P=0.07). Hundred and thirty-three patients undergone lumbar aortic lymphadenectomy, with node involvement found in 83% of patients in the hysterectomy group and 51% of patients in the control group (P=0.0053).
  
  
  CONCLUSIONS
  Indication of lumbar aortic lymphadenectomy should be taken in better consideration in patients with history of inter-adnexial hysterectomy. These data must be thoroughly assessed with a prospective multicenter comparative study.
authors: Service de gynécologie obstétrique, centre Jean-Perrin, 58, rue Montalembert, 63000 Clermont-Ferrand, France. Electronic address: caro.pcm@hotmail.fr.
authors: C
authors: C
authors: Cornou
authors: Service de chirurgie cancérologique, centre Jean-Perrin, Clermont-Ferrand, France.
authors: A C
authors: AC
authors: Philippe
authors: Service de chirurgie cancérologique, centre Jean-Perrin, Clermont-Ferrand, France.
authors: G
authors: G
authors: Le Bouedec
authors: Service d'anatomopathologie, centre Jean-Perrin, Clermont-Ferrand, France.
authors: M M
authors: MM
authors: Dauplat
authors: Service de chirurgie cancérologique, centre Jean-Perrin, Clermont-Ferrand, France.
authors: J
authors: J
authors: Dauplat
authors: Service de chirurgie cancérologique, centre Jean-Perrin, Clermont-Ferrand, France. Electronic address: christophe.pomel@cjp.fr.
authors: C
authors: C
authors: Pomel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000706:statistics & numerical data*; D008197:Lymph Node Excision / Q000706:statistics & numerical data*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000453:epidemiology*; D012189:Retrospective Studies
keywords: Cancer de l’ovaire; Carcinose péritonéale; Hysterectomy; Hystérectomie; Lymphadenectomy; Lymphadénectomie; Ovarian cancer; Peritoneal carcinomatosis