title: Visual recovery following open globe injury with initial no light perception.
abstract: BACKGROUND
  The purpose of this study was to analyze eyes presenting with no light perception (NLP) after open globe injury (OGI) to determine visual outcomes and prognostic indicators for visual recovery.
  
  
  METHODS
  The records of consecutive patients with at least 6 months of follow-up presenting with OGI and NLP to a single institution between January 1, 2003 and December 31, 2013 were reviewed for demographics, ophthalmic history, context and characteristics of injury, ocular examination findings, surgical interventions, and follow-up visual acuity. Unpaired t-tests and Fisher's Exact tests were used for statistical analysis.
  
  
  RESULTS
  Twenty-five patients met our inclusion criteria. The mean age was 50.4±25.5 (range 8-91) years. Four patients (16%) regained vision (hand motion in three patients and light perception in one patient) while 21 patients (84%) remained with NLP or had a prosthesis at final follow-up. Fourteen eyes (56%) were enucleated; nine (36%) were secondary enucleations. Although the sample sizes were small, neither ocular trauma score nor wound size was found to predict visual recovery.
  
  
  CONCLUSIONS
  Four patients regained some vision after presenting with NLP due to OGI. These findings suggest that, in select cases, physicians should discuss the possibility of regaining some vision.
authors: Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT, USA.
authors: Yong S
authors: YS
authors: Han
authors: Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT, USA.
authors: Shaheen C
authors: SC
authors: Kavoussi
authors: Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT, USA.
authors: Ron A
authors: RA
authors: Adelman
keywords: no light perception; open globe injury; visual recovery; vitreoretinal surgery