title: Cutaneous melioidosis with unusual histological features.
abstract: Melioidosis is caused by the saprophytic gram-negative bacillus Burkholderia pseudomallei, and has varied presentations, with cutaneous manifestations occurring in about 13% of cases. The usual histopathological features of melioidosis are suppurative to chronic granulomatous inflammation. Recommended treatment of melioidosis is sequential use of intravenous followed by oral antibiotics for a few months, although oral antibiotics alone can be used in primary cutaneous melioidosis. We report a case of cutaneous melioidosis in a healthy young man, with the unusual histopathological feature of lymphoplasmacytic inflammation, and failing an initial trial of oral antibiotics alone.
authors: National Skin Centre, Singapore.
authors: B
authors: B
authors: Yeo
authors: National Skin Centre, Singapore.
authors: J
authors: J
authors: Lee
authors: National Skin Centre, Singapore.
authors: U
authors: U
authors: Alagappan
authors: National Skin Centre, Singapore.
authors: J Y
authors: JY
authors: Pan
mesh_terms: D061605:Administration, Intravenous; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016957:Burkholderia pseudomallei / Q000302:isolation & purification; D006801:Humans; D007717:Knee; D008297:Male; D008554:Melioidosis / Q000473:pathology*; D017192:Skin Diseases, Bacterial / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents