title: Palladium-Catalyzed Oxidative Cycloisomerization of 2-Cinnamyl-1,3-Dicarbonyls: Synthesis of Functionalized 2-Benzyl Furans.
abstract: A new palladium-catalyzed intramolecular oxidative cycloisomerization of readily available starting materials, 2-cinnamyl-1,3-dicarbonyls, has been demonstrated for the creation of structurally diverse 2-benzyl furans. The cycloisomerization occurs by a regioselective 5-exo-trig pathway. The reaction shows a broad substrate scope with good to excellent yields. Furthermore, a one-pot procedure has been executed by using readily available cinnamyl alcohols and 1,3-diketones.
authors: Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri, Indore By-pass Road, Bhopal-462066 (India).
authors: Rajender
authors: R
authors: Nallagonda
authors: Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri, Indore By-pass Road, Bhopal-462066 (India).
authors: Reddy Rajasekhar
authors: RR
authors: Reddy
authors: Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri, Indore By-pass Road, Bhopal-462066 (India). pghorai@iiserb.ac.in.
authors: Prasanta
authors: P
authors: Ghorai
keywords: cycloisomerization; furans; heterocycles; oxidation; palladium