title: Effectiveness of bronchial thermoplasty in severe asthma in 'real life' patients compared with those recruited to clinical trials in the same centre.
abstract: Published information on the effectiveness of bronchial thermoplasty (BT) for severe asthma in 'real life' patients is limited. We compared safety and efficacy outcomes 12 months post procedure in 10 clinic patients and 15 patients recruited to clinical trials of BT at the same centre. Baseline asthma severity was greater in the clinic group. Adverse events were similar. Clinical improvements occurred in 50% of the clinic patients compared with 73% of the research patients.
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Stephen
authors: S
authors: Bicknell
authors: Department of Respiratory Medicine, Gartnavel General Hospital, Glasgow G12 OYN, UK rekhachaudhuri@yahoo.com.
authors: Rekha
authors: R
authors: Chaudhuri
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Nicola
authors: N
authors: Lee
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Malcolm
authors: M
authors: Shepherd
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Mark
authors: M
authors: Spears
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Nick
authors: N
authors: Pitman
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Euan
authors: E
authors: Cameron
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Douglas
authors: D
authors: Cowan
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Julie
authors: J
authors: Nixon
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK.
authors: Joyce
authors: J
authors: Thompson
authors: Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
authors: Charles
authors: C
authors: McSharry
authors: Respiratory Medicine, Gartnavel General Hospital, Glasgow, UK Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.
authors: Neil C
authors: NC
authors: Thomson
mesh_terms: D000328:Adult; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D001980:Bronchi / Q000503:physiopathology / Q000601:surgery*; D001999:Bronchoscopy / Q000009:adverse effects / Q000379:methods*; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods*; D002986:Clinical Trials as Topic / Q000379:methods*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D020127:Recovery of Function; D012606:Scotland; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D018927:Anti-Asthmatic Agents
keywords: asthma; bronchial thermoplasty; bronchoscopy