title: Clinical Characteristics, Laboratory Identification, and In Vitro Antifungal Susceptibility of Yarrowia (Candida) lipolytica Isolates Causing Fungemia: a Multicenter, Prospective Surveillance Study.
abstract: Our case series showed that uncomplicated Yarrowia lipolytica fungemia might be treated with catheter removal alone. The Vitek 2 YST identification (ID) card system, matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), and internal transcribed spacer and 25S nuclear ribosomal DNA (nrDNA) gene sequencing provided reliable identification. All isolates had low MICs to voriconazole, echinocandins, and amphotericin B.
authors: Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
authors: Ying
authors: Y
authors: Zhao
authors: State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong Department of Microbiology, The University of Hong Kong, Hong Kong Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong.
authors: Jasper Fuk-Woo
authors: JF
authors: Chan
authors: Department of Microbiology, The University of Hong Kong, Hong Kong.
authors: Chi-Ching
authors: http://orcid.org/0000-0001-6705-2866
authors: CC
authors: Tsang
authors: Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
authors: He
authors: H
authors: Wang
authors: Department of Microbiology, the First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
authors: Dawen
authors: D
authors: Guo
authors: Department of Clinical Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
authors: Yuhong
authors: Y
authors: Pan
authors: Division of Clinical Microbiology, Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
authors: Yuling
authors: Y
authors: Xiao
authors: Laboratory Center, General Hospital of Tianjin Medical University, Tianjin, China.
authors: Na
authors: N
authors: Yue
authors: State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong.
authors: Jonathan Hon-Kwan
authors: http://orcid.org/0000-0002-7510-1696
authors: JH
authors: Chen
authors: State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong Department of Microbiology, The University of Hong Kong, Hong Kong Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong.
authors: Susanna Kar-Pui
authors: SK
authors: Lau
authors: Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China xycpumch@139.com pcywoo@hku.hk.
authors: Yingchun
authors: Y
authors: Xu
authors: State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong Department of Microbiology, The University of Hong Kong, Hong Kong Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong xycpumch@139.com pcywoo@hku.hk.
authors: Patrick Chiu-Yat
authors: PC
authors: Woo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000627:therapeutic use*; D001483:Base Sequence; D055499:Catheter-Related Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D002405:Catheterization, Central Venous / Q000009:adverse effects; D002406:Catheterization, Peripheral / Q000009:adverse effects; D002675:Child, Preschool; D021903:DNA, Ribosomal Spacer / Q000235:genetics*; D054714:Echinocandins / Q000494:pharmacology; D005260:Female; D016469:Fungemia / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology; D006760:Hospitalization; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D008969:Molecular Sequence Data; D011446:Prospective Studies; D017422:Sequence Analysis, DNA; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods; D065819:Voriconazole / Q000494:pharmacology; D025062:Yarrowia / Q000187:drug effects / Q000235:genetics*
chemical_list: D000935:Antifungal Agents; D021903:DNA, Ribosomal Spacer; D054714:Echinocandins; D000666:Amphotericin B; D065819:Voriconazole