title: How should we choose the 'best' embryo? A commentary on behalf of the British Fertility Society and the Association of Clinical Embryologists.
abstract: Embryo selection to improve pregnancy rates remains a significant challenge in IVF. Non-invasive and invasive methods of embryo selection include morphological assessment, metabolomics, time-lapse imaging and preimplantation genetic screening. To date, none has been shown conclusively to yield improved implantation and live birth rates. This review summarises current understanding of methods for embryo selection.
authors: a Assisted Conception Unit, Guy's & St Thomas' NHS Foundation Trust, Guy's Hospital , London , UK.
authors: Virginia N
authors: VN
authors: Bolton
authors: b Hull IVF Unit, The Women & Children's Hospital, Hull Royal Infirmary , Hull , UK.
authors: Christine
authors: C
authors: Leary
authors: c Cambridge IVF, Cambridge University Hospitals NHS Trust , Cambridge , UK.
authors: Stephen
authors: S
authors: Harbottle
authors: d Jessop Fertility, Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield , UK.
authors: Rachel
authors: R
authors: Cutting
authors: e Genetics, Embryology and IVF Group, Institute for Women's Health, University College London , London , UK.
authors: Joyce C
authors: JC
authors: Harper
mesh_terms: D015925:Cryopreservation; D010064:Embryo Implantation / Q000502:physiology; D004622:Embryo, Mammalian / Q000033:anatomy & histology / Q000502:physiology*; D004626:Embryology / Q000379:methods*; D005260:Female; D005298:Fertility; D005307:Fertilization in Vitro; D005820:Genetic Testing / Q000379:methods; D006801:Humans; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D018873:Pregnancy Rate; D019836:Preimplantation Diagnosis; D056826:Single Embryo Transfer / Q000379:methods; D012955:Societies, Medical; D059008:Time-Lapse Imaging; D006113:United Kingdom
keywords: IVF; embryo viability; human embryo