title: Comparing Patient-Reported Outcomes Measure Information System Depression Scale with Legacy Depression Measures in a Community Sample of Older Adults with Varying Levels of Cognitive Functioning.
abstract: OBJECTIVE
  This study evaluated the utility of Patient-Reported Outcomes Measure Information System Depression Scale (PROMIS-8a) compared with selected "Legacy" depression scales, including the Montgomery-Asberg Depression Rating Scale (MADRS), Geriatric Depression Scale (GDS), and GDS-Short Form (GDS-SF). Additionally, the measures' properties were assessed across levels of cognitive functioning.
  
  
  METHODS
  This cross-sectional analysis was extracted from a prospective cohort study. PROMIS-8a and Legacy depression measures were administered to individuals aged at least 70 years grouped by cognitive status based on the Saint Louis University Mental Status Examination. McNemar tests were run to determine if measures categorized the absence or presence of depression differently and item analysis evaluated classification discrepancies.
  
  
  RESULTS
  Sample mean age was 78, and most participants were women (71%), white (79%), with at least a high school education (89%). The percentage of individuals with at least mild depression was similar across measures (20.7% PROMIS-8a, 19.0% MADRS, 17.9% GDS, 13.9% GDS-SF). PROMIS-8a total score correlated moderately with MADRS (r = 0.56, df = 295, p <0.01), GDS (r = 0.68, df = 291, p <0.01), and GDS-SF (r = 0.60, df = 291, p <0.01), and predictive validity of the measures was similar. There were no significant mean differences on depression measures by cognitive status.
  
  
  CONCLUSIONS
  Although all measures identified a similar percent of depressed individuals, the classification differed by measure. Item analysis showed that PROMIS-8a was more likely to identify feelings of dysphoria while the MADRS and GDS were more likely to identify physiologic aspects of depression. Given the brevity and ease of administration of the PROMIS-8a, it appears to be a useful depression screen for community-dwelling older adults.
authors: Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH; Neurological and Behavioral Outcomes Center, University Hospitals Case Medical Center, Cleveland, OH. Electronic address: Jennifer.levin@uhhospitals.org.
authors: Jennifer B
authors: JB
authors: Levin
authors: Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH.
authors: Michelle E
authors: ME
authors: Aebi
authors: Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, OH.
authors: Kathleen A
authors: KA
authors: Smyth
authors: Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, OH; Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, OH; Neurological and Behavioral Outcomes Center, University Hospitals Case Medical Center, Cleveland, OH.
authors: Curtis
authors: C
authors: Tatsuoka
authors: Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH; Neurological and Behavioral Outcomes Center, University Hospitals Case Medical Center, Cleveland, OH.
authors: Johnny
authors: J
authors: Sams
authors: Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH.
authors: Thomas
authors: T
authors: Scheidemantel
authors: Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH; Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, OH; Neurological and Behavioral Outcomes Center, University Hospitals Case Medical Center, Cleveland, OH.
authors: Martha
authors: M
authors: Sajatovic
mesh_terms: D000368:Aged; D003072:Cognition Disorders / Q000523:psychology*; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D057566:Self Report
keywords: Depression; Geriatric Depression Scale (GDS); Montgomery-Asberg Depression Rating Scale (MADRS); PROMIS; cognitive functioning