title: Maximal Fat Oxidation Rate during Exercise in Korean Women with Type 2 Diabetes Mellitus.
abstract: BACKGROUND
  The purpose of this study was to determine the appropriate exercise intensity associated with maximum fat oxidation, improvement of body composition, and metabolic status in Korean women with type 2 diabetes mellitus (T2DM).
  
  
  METHODS
  The study included a T2DM group (12 women) and a control group (12 women). The groups were matched in age and body mass index. The subjects performed a graded exercise test on a cycle ergometer to measure their maximal fat oxidation (Fatmax). We also measured their body composition, metabolic profiles, and mitochondrial DNA (mtDNA).
  
  
  RESULTS
  The exercise intensity for Fatmax was significantly lower in the T2DM group (34.19% maximal oxygen uptake [VO2 max]) than the control group (51.80% VO2 max). Additionally, the rate of fat oxidation during exercise (P<0.05) and mtDNA (P<0.05) were significantly lower in the T2DM group than the control group. The VO2 max level (P<0.001) and the insulin level (P<0.05) were positively correlated with the rate of fat oxidation.
  
  
  CONCLUSIONS
  The results of this study suggest lower exercise intensity that achieves Fatmax is recommended for improving fat oxidation and enhancing fitness levels in Korean women with T2DM. Our data could be useful when considering an exercise regimen to improve health and fitness.
authors: Department of Kinesiology and Medical Science, Dankook University College of Medicine, Cheonan, Korea.
authors: Min Hwa
authors: MH
authors: Suk
authors: Diabetes Center, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors: Yeo-Jin
authors: YJ
authors: Moon
authors: Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors: Sung Woo
authors: SW
authors: Park
authors: Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors: Cheol-Young
authors: CY
authors: Park
authors: Department of Kinesiology and Medical Science, Dankook University College of Medicine, Cheonan, Korea.
authors: Yun A
authors: YA
authors: Shin
keywords: Diabetes mellitus, type 2; Exercise prescription; Maximal fat oxidation; Maximal oxygen uptake