title: Reliability and validity of the Manual Ability Measure-36 in persons with Charcot-Marie-Tooth disease.
abstract: METHODS
  Descriptive, clinical measurement.
  
  
  BACKGROUND
  Charcot-Marie-Tooth disease (CMT) is a genetic disorder that results in demyelination or axonal degeneration in peripheral nerves. Characteristic symptoms include decreased muscle strength and sensation, particularly in the hands and feet.
  
  
  OBJECTIVE
  Examine the reliability and validity of the Manual Ability Measure (MAM-36), a 36-item self-report questionnaire specific to hand function, in persons with CMT.
  
  
  METHODS
  Fourteen participants with CMT completed the MAM-36 at two points one week apart. Participants were also administered performance-based tests for grip and pinch strength, dexterity, and sensation.
  
  
  RESULTS
  The test-retest intraclass correlation coefficient (ICC) for the MAM-36 was 0.96. Pearson correlation coefficients showed fair to good relationships (r = 0.41-0.64) between the MAM-36 scores and most of the performance tests.
  
  
  CONCLUSIONS
  The MAM-36 is a reliable and valid assessment tool for measuring hand function during everyday tasks in persons with CMT.
  
  
  METHODS
  IIb.
authors: University of New Mexico, Occupational Therapy Graduate Program, Albuquerque, NM, USA. Electronic address: jpoole@salud.unm.edu.
authors: Janet L
authors: JL
authors: Poole
authors: University of New Mexico Hospital, Albuquerque, NM, USA.
authors: Matthew
authors: M
authors: Huffman
authors: Presbyterian HealthCare, Albuquerque, NM, USA.
authors: Anaclaire
authors: A
authors: Hunter
authors: Albuquerque, NM, USA.
authors: Clare
authors: C
authors: Mares
authors: University of New Mexico, Occupational Therapy Graduate Program, Albuquerque, NM, USA.
authors: Patricia
authors: P
authors: Siegel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002607:Charcot-Marie-Tooth Disease / Q000503:physiopathology*; D004185:Disability Evaluation; D005260:Female; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009048:Motor Skills / Q000502:physiology*; D015203:Reproducibility of Results; D012677:Sensation / Q000502:physiology*
keywords: Charcot-Marie-Tooth disease; Manual ability; Manual ability measure; Outcome measure