title: Platelet GPVI repairs its own damage.
abstract: In this issue of Blood, Gros et al report that glycoprotein VI (GPVI) promotes the proinflammatory role of platelets by increasing neutrophil secretion and toxicity while at the same time repairing the vascular damage inflicted by neutrophil activation, thereby maintaining vascular integrity. Significantly, this effect is independent of hemostasis.
authors: UNIVERSITY OF BIRMINGHAM.
authors: Julie
authors: J
authors: Rayes
authors: UNIVERSITY OF BIRMINGHAM.
authors: Steve P
authors: SP
authors: Watson
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000378:metabolism*; D007105:Immune Complex Diseases / Q000473:pathology*; D007249:Inflammation / Q000473:pathology*; D009504:Neutrophils / Q000473:pathology*; D010980:Platelet Membrane Glycoproteins / Q000378:metabolism*
chemical_list: D010980:Platelet Membrane Glycoproteins