title: Unfavourable short-term outcomes of a poly-L/D-lactide scaffold for thumb trapeziometacarpal arthroplasty.
abstract: The bioabsorbable poly-L-D-lactide joint scaffold arthroplasty is a recent attempt in the reconstruction of small joints in rheumatoid patients. In this study, we analysed the 1-year clinical, functional and radiologic results of partial trapeziectomy with the poly-L-D-lactide (96/4) joint scaffold in 23 patients with isolated trapeziometacarpal osteoarthritis. The results showed that the procedure provided pain relief and improvement in overall function according to the Quick Disabilities of the Arm, Shoulder and Hand score in most patients. However, radiographs demonstrated a high frequency of osteolysis around the implant. Seven patients developed clinically manifested foreign-body reactions 6 months to 1 year after surgery. The reason for the unexpected tissue reactions may relate to excessive mechanical cyclic loading of the implant. The outcomes of this implant in our patients have not been sufficiently beneficial and we have discontinued use of this implant in isolated trapeziometacarpal osteoarthritis.
authors: Department of Hand Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland simo.mattila@hus.fi.
authors: S
authors: S
authors: Mattila
authors: Department of Hand Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
authors: E
authors: E
authors: Waris
mesh_terms: D000328:Adult; D000368:Aged; D019643:Arthroplasty, Replacement; D052737:Carpometacarpal Joints; D005260:Female; D018737:Hand Strength; D006801:Humans; D007595:Joint Prosthesis; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011091:Polyesters; D011474:Prosthesis Design; D011859:Radiography; D020127:Recovery of Function; D013933:Thumb; D013997:Time Factors; D051222:Trapezium Bone / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D011091:Polyesters; C033616:poly(lactide)
keywords: Arthroplasty; Poly-L/D-lactide (PLA); bioabsorbable; carpometacarpal joint (CMC); implant; interposition; osteoarthritis