title: Simultaneous spectrophotometric determination of copper, cobalt, nickel and iron in foodstuffs and vegetables with a new bis thiosemicarbazone ligand using chemometric approaches.
abstract: A newly synthesized bis thiosemicarbazone ligand, (2Z,2'Z)-2,2'-((4S,5R)-4,5,6-trihydroxyhexane-1,2-diylidene)bis(N-phenylhydrazinecarbothioamide), was used to make a complex with Cu(2+), Ni(2+), Co(2+) and Fe(3+) for their simultaneous spectrophotometric determination using chemometric methods. By Job's method, the ratio of metal to ligand in Ni(2+) was found to be 1:2, whereas it was 1:4 for the others. The effect of pH on the sensitivity and selectivity of the formed complexes was studied according to the net analyte signal (NAS). Under optimum conditions, the calibration graphs were linear in the ranges of 0.10-3.83, 0.20-3.83, 0.23-5.23 and 0.32-8.12 mg L(-1) with the detection limits of 2, 3, 4 and 10 μg L(-1) for Cu(2+), Co(2+), Ni(2+) and Fe(3+) respectively. The OSC-PLS1 for Cu(2+) and Ni(2+), the PLS1 for Co(2+) and the PC-FFANN for Fe(3+) were selected as the best models. The selected models were successfully applied for the simultaneous determination of elements in some foodstuffs and vegetables.
authors: Department of Chemistry, Faculty of Science, Vali-e-Asr University, 77188-97111 Rafsanjan, Iran. Electronic address: m.rohani@vru.ac.ir.
authors: Masoud
authors: M
authors: Rohani Moghadam
authors: Department of Chemistry, Faculty of Science, Vali-e-Asr University, 77188-97111 Rafsanjan, Iran.
authors: Sayedeh Maria
authors: SM
authors: Poorakbarian Jahromi
authors: Department of Chemistry, Faculty of Science, Vali-e-Asr University, 77188-97111 Rafsanjan, Iran.
authors: Ali
authors: A
authors: Darehkordi
mesh_terms: D003035:Cobalt / Q000737:chemistry*; D056831:Coordination Complexes / Q000737:chemistry; D003300:Copper / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008024:Ligands; D009532:Nickel / Q000737:chemistry*; D013053:Spectrophotometry / Q000379:methods*; D013882:Thiosemicarbazones / Q000737:chemistry*; D014675:Vegetables / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D008024:Ligands; D013882:Thiosemicarbazones; D003035:Cobalt; D003300:Copper; D009532:Nickel; D007501:Iron
keywords: Acetic acid (PubChem CID 176); Bis thiosemicarbazone; Chemometrics; Cobalt nitrate hexahydrate (PubChem CID 24821); Copper(II) sulfate pentahydrate (PubChem CID 24463); Foodstuffs; Iron trichloride (PubChem CID 24380); Metal ions; Nickel(II) nitrate hexahydrate (PubChem CID 61630); Simultaneous determination; Sodium acetate (PubChem CID 517045); Vegetables