title: Anterior Segment Optical Coherence Tomography Assessment After Laser Capsulotomy in Pseudophakic Eyes With Pseudoexfoliation.
abstract: OBJECTIVE
  To assess changes in anterior-chamber depth (ACD) and angle width after neodymium:yttrium aluminum garnet (Nd:YAG) laser capsulotomy pseudophakia in eyes with pseudoexfoliation (PEX).
  
  
  METHODS
  This prospective and interventional case series study included 25 pseudophakic eyes of 25 patients with PEX and 26 pseudophakic eyes of 26 patients without PEX scheduled for Nd:YAG laser capsulotomy in a single institution. Anterior-chamber depth and angle width were measured with anterior segment optical coherence tomography before and three days after Nd:YAG laser capsulotomy. Preoperative and postoperative measurements of ACD and angle width included the angle opening distance (AOD), measured as the perpendicular distance from the trabecular meshwork at 500 and 750 mm anterior to the scleral spur to the anterior iris surface (AOD500 and AOD750, respectively) and anterior-chamber angle (ACA) in the nasal and temporal quadrants. Main outcome measures were the changes in ACD and angle width parameters.
  
  
  RESULTS
  The mean ACD, AOD500, AOD750, and ACA (nasal and temporal) measurements were 3.67±0.12 mm, 0.63±0.05 mm and 0.65±0.05 mm, 0.67±0.06 mm and 0.77±0.04 mm, 35.25±1.69° and 35.37±1.68° in eyes with PEX and 3.73±0.11 mm, 0.6±0.05 mm and 0.63±0.05 mm, 0.66±0.06 mm and 0.74±0.06 mm, 34.24±1.6° and 34.6±1.47° in control eyes, respectively (P>0.05 for all). After Nd:YAG laser capsulotomy, mean ACD, AOD500, AOD750, and ACA (nasal and temporal) measurements were 3.76±0.09 mm, 0.73±0.05 mm and 0.76±0.05 mm, 0.75±0.06 mm and 0.87±0.04 mm, 36.82±1.46° and 35.06±1.52° in eyes with PEX and 3.77±0.1 mm, 0.68±0.06 mm and 0.72±0.06 mm, 0.72±0.05 mm and 0.84±0.06 mm, 34.95±1.4° and 35.79±1.36° in control eyes, respectively (P=0.811, P=0.019, P=0.021, P=0.109, P=0.126, P=0.001, and P=0.01, respectively).
  
  
  CONCLUSIONS
  The depth and width of the anterior chamber in eyes with PEX and in control eyes increased significantly after Nd:YAG laser capsulotomy. The change in the width of the anterior chamber in eyes PEX was statistically significant comparing control eyes.
authors: Department of Ophthalmology (M.E., S.K.E., G.G., M.O., C.A., C.A.A.), Istanbul Medipol University School of Medicine, Istanbul, Turkey; and Department of Ophthalmology (H.B.), Medeniyet University School of Medicine, Istanbul, Turkey.
authors: Mustafa
authors: M
authors: Eliacik
authors: Sevil
authors: S
authors: Karaman Erdur
authors: Gokhan
authors: G
authors: Gulkilik
authors: Mustafa
authors: M
authors: Ozsutcu
authors: Cengiz
authors: C
authors: Aras
authors: Huseyin
authors: H
authors: Bayramlar
authors: Cemile Anil
authors: CA
authors: Aslan
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology*; D016022:Case-Control Studies; D017889:Exfoliation Syndrome / Q000473:pathology*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D053685:Laser Therapy; D007903:Lens Capsule, Crystalline / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D064727:Posterior Capsulotomy / Q000379:methods; D011446:Prospective Studies; D019591:Pseudophakia / Q000473:pathology / Q000601:surgery*; D041623:Tomography, Optical Coherence / Q000379:methods*