title: Effect of Optically Active Ethyl 2-Phthalimidooxypropionate on the Growth of Cress, Lepidium sativum.
abstract: The effects of 2-phthalimidooxyalkanoic acid derivatives on the germination and root-growth of cress were examined. Since 2-phthalimidooxypropionates were most effective, the optically active ethyl esters were prepared. As the result of biological testing, the (S)-(-)-isomer exhibited stronger activity than the (R)-(+)-isomer. This result is contrary to those from commercial herbicides with similar structures, phenoxy- and oxyphenoxy-propionate-type compounds, where the (R)-isomers are generally known to be the active principles.
authors: a Faculty of Agriculture, Ehime University.
authors: Y
authors: Y
authors: Takekida
authors: M
authors: M
authors: Okazaki
authors: Y
authors: Y
authors: Shuto
mesh_terms: D018525:Germination / Q000187:drug effects; D006540:Herbicides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D031220:Lepidium sativum / Q000187:drug effects* / Q000254:growth & development; D009904:Optical Rotation; D010797:Phthalimides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000187:drug effects* / Q000254:growth & development; D011422:Propionates / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D012639:Seeds / Q000187:drug effects / Q000254:growth & development; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D006540:Herbicides; D010797:Phthalimides; D011422:Propionates
keywords: 2-phthalimidooxypropionate; cress test; optical activity; phthalimidooxy derivatives; plant growth inhibition