title: [Analysis of Factors Influencing Posttransfusion Effectiveness in 26045 Cases of Platelet Transfusion].
abstract: OBJECTIVE
  To investigate the factors influencing platelet transfusion results so as to improve the platelet transfusion efficiency.
  
  
  METHODS
  According to the clinical symptoms (bleeding condition is stopped or improved)and the corrected count of increment (CCI), the patients were divided into efficient transfusion and inefficient transfusion groups. A total of 20 671 patients' clinical data and main platelet transfusion parameters in 26 045 tranfusions including platelet count of per- and post- transfusion, platelet component sorts, storage time and transfusion number were analysed.
  
  
  RESULTS
  The comparison of platelet transfusion efficiency in age and sex between two groups did not showed statistical difference (P > 0.05), the platelet count before transfusion between two groups showed statistical difference (t = -5.59, P < 0.001) after converting to log, a significant linear correlation did not exist between storage time of the platelet and CCI (corrected count of increment), but there was statistical difference in transfusion efficiency of patients with different diseases. The patients with hematologic diseases showed lower efficiency of platelet transfusion. According to the results of Wilcocon test detection, there was difference between different times of transfusion and transfusion efficiency, that is to say, the transfusion frequency was higher, the transfusion efficency was lower. The Fisher test indicated that the transfusion efficiency of single platelet transfusion was lower than that of transfussed platelet with other blood components (P < 0.01).
  
  
  CONCLUSIONS
  Platelet transfusion efficiency associates with many factors, including different diseases, whether being transfused with other blood components, the platelet count before transfusion, transfusion frequency, but the time of storage does not relate to the transfusion efficacy.
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors: Lin-Feng
authors: LF
authors: Chen
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors: Ji-Chun
authors: JC
authors: Pan
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors: Qian
authors: Q
authors: Feng
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors: Yuan-Yuan
authors: YY
authors: Luo
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors: Yang
authors: Y
authors: Yu
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors: Yuan
authors: Y
authors: Zhuang
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors: Hui
authors: H
authors: Li
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China.
authors: Yan-Nan
authors: YN
authors: Feng
authors: Department of Transfusion, Chinese PLA General Hospital, Beijing 100853, China. E-mail: dqwang@sina.vip.com.
authors: De-Qing
authors: DQ
authors: Wang
mesh_terms: D001792:Blood Platelets; D006402:Hematologic Diseases; D006801:Humans; D010976:Platelet Count; D017713:Platelet Transfusion