title: [EFFECTS OF WEIGHT LOSS AFTER BARIATRIC SURGERY ON PULMONARY FUNCTION TESTS AND OBSTRUCTIVE SLEEP APNEA IN MORBIDLY OBESE WOMEN].
abstract: BACKGROUND
  obesity impacts on respiratory function and also it acts as a risk factor for obstructive sleep apnea (OSA).
  
  
  OBJECTIVE
  to study the effects of bariatric surgery on pulmonary function tests and on OSA in morbidly obese women over 4 years.
  
  
  METHODS
  fifteen morbidly obese women (mean body mass index [BMI] 50.52 ± 12.71 kg.m-2, mean age 40.13 ± 10.06 years) underwent pulmonary function tests (PFT) in two opportunities (before and after weight loss surgery). PFT included spirometry, body plethysmography and measure of maximal inspiratory mouth pressure (PImax) and of tension-time index for inspiratory muscles. Also, in both opportunities, resting arterial blood gas tensions were evaluated and a full night sleep register was performed.
  
  
  RESULTS
  BMI significantly decreased after bariatric surgery (-44.07 kg.m-2 [CI 95% -38.32 - -49.81]). Also, there was a significantly increase in forced expiratory volume in 1 second (FEV1) (p < 0.01), forced vital capacity (FVC) (p < 0.01), expiratory reserve volume (ERV) (p = 0.040), functional residual capacity (FRC) (p = 0.009) and a decline in airways resistance (Raw) (p = 0.018). Concerning sleep registers, apnea hypopnea index (p = 0.001) and desaturation index (p = 0.001) were also reduced after weight loss. Improve in ERV had a significant correlation with weight loss (r = 0.774, p = 0.024). Conclussions: pulmonary function tests and apnea hypopnea index improve after bariatric surgery in mor bidly obese women. Improvement of ERV is well correlated with weight loss.
authors: Servicio de Neumología. Hospital Universitario La Paz. IdiPAZ. Departamento de Medicina y Cirugía. Universidad Autónoma de Madrid.. carlinjavier@hotmail.com.
authors: Ana
authors: A
authors: Santiago
authors: Servicio de Neumología. Hospital Universitario La Paz. IdiPAZ. Departamento de Medicina y Cirugía. Universidad Autónoma de Madrid.. carlinjavier@hotmail.com.
authors: Carlos
authors: C
authors: Carpio
authors: Servicio de Radiología. Hospital Universitario de La Princesa. Universidad Autónoma de Madrid.. carlinjavier@hotmail.com.
authors: Paloma
authors: P
authors: Caballero
authors: Servicio de Cirugía General. Hospital Universitario Príncipe de Asturias. Departamento de Cirugía. Universidad Alcalá de Henares.. carlinjavier@hotmail.com.
authors: Antonio
authors: A
authors: Martín-Duce
authors: Servicio de Cirugía General. Hospital Universitario La Paz, Madrid.. carlinjavier@hotmail.com.
authors: Gregorio
authors: G
authors: Vesperinas
authors: Servicio de Neumología. Hospital San Pedro Alcántara, Cáceres.. carlinjavier@hotmail.com.
authors: Francisco
authors: F
authors: Gómez de Terreros
authors: Servicio de Neumología. Hospital Universitario La Paz. IdiPAZ. Departamento de Medicina y Cirugía. Universidad Autónoma de Madrid.. carlinjavier@hotmail.com.
authors: M A
authors: MA
authors: Gómez Mendieta
authors: Servicio de Neumología. Hospital Universitario La Paz. IdiPAZ. Departamento de Medicina y Cirugía. Universidad Autónoma de Madrid.. carlinjavier@hotmail.com.
authors: Rodolfo
authors: R
authors: Álvarez-Sala
authors: Servicio de Medicina Intensiva. Hospital Universitario La Paz. IdiPAZ. Universidad Autónoma de Madrid, España.. carlinjavier@hotmail.com.
authors: Abelardo
authors: A
authors: García de Lorenzo
mesh_terms: D000328:Adult; D050110:Bariatric Surgery / Q000009:adverse effects; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D011184:Postoperative Period; D012129:Respiratory Function Tests; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D015431:Weight Loss