title: Microbial oxidative stress response: Novel insights from environmental facultative anaerobic bacteria.
abstract: Facultative bacteria can grow under either oxic or anoxic conditions. While oxygen provides substantial advantages in energy yield by respiration, it can become life-threatening because of reactive oxygen species that derive from the molecule naturally. Thus, to survive and thrive in a given niche, these bacteria have to constantly regulate physiological processes to make maximum benefits from oxygen respiration while restraining oxidative stress. Molecular mechanisms and physiological consequences of oxidative stress have been under extensive investigation for decades, mostly on research model Escherichia coli, from which our understanding of bacterial oxidative stress response is largely derived. Nevertheless, given that bacteria live in enormously diverse environments, to cope with oxidative stress different strategies are conceivably developed.
authors: Institute of Microbiology and College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China.
authors: Huihui
authors: H
authors: Fu
authors: Institute of Microbiology and College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China. Electronic address: jieyuan@zju.edu.cn.
authors: Jie
authors: J
authors: Yuan
authors: Institute of Microbiology and College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China. Electronic address: haichung@zju.edu.cn.
authors: Haichun
authors: H
authors: Gao
mesh_terms: D001421:Bacteria, Anaerobic / Q000502:physiology*; D018384:Oxidative Stress / Q000502:physiology*; D010100:Oxygen / Q000378:metabolism*
chemical_list: D010100:Oxygen
keywords: Bacteria; Hydrogen peroxide; Oxidative stress response; OxyR; Regulation; Viability