title: Vitamin D and its relation with ionic calcium, parathyroid hormone, maternal and neonatal characteristics in pregnancy after roux-en-Y gastric bypass.
abstract: OBJECTIVE
  The objective of this study was to evaluate vitamin D nutritional status and its relation with ionic calcium, parathyroid hormone (PTH), maternal anthropometry and perinatal outcomes in pregnant women who previously underwent Roux-en-Y gastric bypass (RYGB) surgery.
  
  
  METHODS
  In a clinic specialized in obesity control located in the city of Rio de Janeiro (Brazil), the following information were collected for adult women who underwent RYGB before pregnancy: serum concentrations of vitamin D [25(OH)D], calcium and PTH per gestational trimester and data on maternal anthropometry, gestational intercurrences and perinatal outcomes.
  
  
  RESULTS
  The present study included 46 post-RYGB pregnant women. The prevalence of pregnant women with deficiency (≤20 ng/mL) or insufficiency (≥21 and 29 ng/mL) of vitamin D was above 70% in all trimesters. The prevalence of calcium deficiency was 15.2% in the first and in the second trimesters and 20% in the third trimester, while the prevalence of excess PTH was 19.6, 30.4 and 32.6% in the first, the second and the third trimesters, respectively. In the second and the third trimesters, a significant difference was observed between concentrations of 25(OH)D, and a negative correlation was observed between concentrations of calcium and PTH. Association of 25(OH)D with urinary tract infection (UTI) was found, but there was no association with calcium, PTH, maternal anthropometry, type of delivery and weight and gestational age at birth
  
  
  CONCLUSIONS
  The post-RYGB pregnant women showed an elevated serum inadequacy (deficiency or insufficiency) of 25(OH)D during pregnancy. Maternal vitamin D status showed no association with maternal variables, except UTI, and the neonatal variables analyzed.
authors: Center for Research On Micronutrients, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373. Edifício dos Institutos, Bloco J, 2° andar, Ilha do Fundão, Rio de Janeiro, CEP: 21941-590, RJ, Brazil. marimd89@hotmail.com.
authors: Marina
authors: M
authors: Medeiros
authors: Center for Research On Micronutrients, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373. Edifício dos Institutos, Bloco J, 2° andar, Ilha do Fundão, Rio de Janeiro, CEP: 21941-590, RJ, Brazil.
authors: Andréa C
authors: AC
authors: Matos
authors: Center for Research On Micronutrients, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373. Edifício dos Institutos, Bloco J, 2° andar, Ilha do Fundão, Rio de Janeiro, CEP: 21941-590, RJ, Brazil.|Clínica Cirúrgica Carlos Saboya, Rio de Janeiro, RJ, Brazil.
authors: Silvia E
authors: SE
authors: Pereira
authors: Center for Research On Micronutrients, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373. Edifício dos Institutos, Bloco J, 2° andar, Ilha do Fundão, Rio de Janeiro, CEP: 21941-590, RJ, Brazil.|Clínica Cirúrgica Carlos Saboya, Rio de Janeiro, RJ, Brazil.
authors: Carlos
authors: C
authors: Saboya
authors: Center for Research On Micronutrients, Josué de Castro Institute of Nutrition, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho, 373. Edifício dos Institutos, Bloco J, 2° andar, Ilha do Fundão, Rio de Janeiro, CEP: 21941-590, RJ, Brazil. aramalho.rj@gmail.com.
authors: Andréa
authors: A
authors: Ramalho
mesh_terms: D000328:Adult; D001938:Brazil; D002118:Calcium / Q000097:blood / Q000378:metabolism*; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D009752:Nutritional Status; D009765:Obesity / Q000150:complications / Q000601:surgery*; D010281:Parathyroid Hormone / Q000097:blood*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011264:Pregnancy Trimesters; D015995:Prevalence; D014807:Vitamin D / Q000097:blood / Q000378:metabolism*; D014808:Vitamin D Deficiency / Q000097:blood / Q000378:metabolism; D015431:Weight Loss; D055815:Young Adult
chemical_list: D010281:Parathyroid Hormone; D014807:Vitamin D; D002118:Calcium
keywords: Bariatric surgery; Calcium; Parathyroid hormone; Perinatal outcome; Pregnancy; Vitamin D