title: Molecular and Biochemical Aspects of the Retina on Refraction.
abstract: Mutant mouse models with specific visual pathway defects offer an advantage to comprehensively investigate the role of specific pathways/neurons involved in refractive development. In this review, we will focus on recent studies using mouse models that have provided insight into retinal pathways and neurotransmitters controlling refractive development. Specifically, we will examine the contributions of rod and cone photoreceptors and the ON and OFF retinal pathways to visually driven eye growth with emphasis on dopaminergic mechanisms.
authors: Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
authors: Ranjay
authors: R
authors: Chakraborty
authors: Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA. Electronic address: mpardue@emory.edu.
authors: Machelle T
authors: MT
authors: Pardue
mesh_terms: D000818:Animals; D006801:Humans; D023421:Models, Animal; D009154:Mutation; D018377:Neurotransmitter Agents / Q000378:metabolism; D012029:Refraction, Ocular / Q000502:physiology*; D012160:Retina / Q000254:growth & development / Q000502:physiology*; D055351:Retinal Neurons / Q000378:metabolism
chemical_list: D018377:Neurotransmitter Agents
keywords: Form deprivation; Mice; Myopia; OFF bipolar cells; ON bipolar cells; Photoreceptors; Refraction