title: Growth hormone used to control intractable bleeding caused by radiation-induced gastritis.
abstract: Intractable bleeding caused by radiation-induced gastritis is rare. We describe a 69-year-old man with intractable hemorrhagic gastritis induced by postoperative radiotherapy for the treatment of esophageal carcinoma. Although anti-secretory therapy with or without octreotide was initiated for hemostasis over three months, melena still occurred off and on, and the patient required blood transfusions to maintain stable hemoglobin. Finally growth hormone was used in the treatment of hemorrhage for two weeks, and hemostasis was successfully achieved. This is the first report that growth hormone has been used to control intractable bleeding caused by radiation-induced gastritis.
authors: Liang Zhang, Wen-Jie Xia, Zheng-Sen Zhang, Xin-Liang Lu, Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors: Liang
authors: L
authors: Zhang
authors: Liang Zhang, Wen-Jie Xia, Zheng-Sen Zhang, Xin-Liang Lu, Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors: Wen-Jie
authors: WJ
authors: Xia
authors: Liang Zhang, Wen-Jie Xia, Zheng-Sen Zhang, Xin-Liang Lu, Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors: Zheng-Sen
authors: ZS
authors: Zhang
authors: Liang Zhang, Wen-Jie Xia, Zheng-Sen Zhang, Xin-Liang Lu, Department of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors: Xin-Liang
authors: XL
authors: Lu
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy*; D016099:Endoscopy, Gastrointestinal; D004938:Esophageal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D000077277:Esophageal Squamous Cell Carcinoma; D005756:Gastritis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D013006:Growth Hormone / Q000627:therapeutic use*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011832:Radiation Injuries / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D006490:Hemostatics; D013006:Growth Hormone
keywords: Growth hormone; Radiation-induced gastritis; Upper gastrointestinal bleeding