title: T-lymphoblastic lymphoma with cutaneous involvement.
abstract: To study dermatological manifestation of T-lymphoblastic lymphoma and to help clinicians in the diagnosis, we report here the case of a 75-year-old patient who presented with violaceous nodules acquired during the last 4 wk and affecting the scalp and right arm. The diagnosis of systemic lymphoma was suggested upon the appearance of cutaneous tumors, palpable lymph nodes and general symptoms including asthenia and weight-loss. The pathology features: positive immunostaining for CD3 and terminal deoxynucleotidyl transferase (TdT) and staging, led us to the final diagnosis of T-lymphoblastic lymphoma (T-LBL) with cutaneous involvement. He received a CHOP regimen as first-line treatment. Unfortunately, the patient relapsed and died 8 mo after the treatment initiation. T-LBL may be diagnosed by skin lesions. Additional immunostaining including TdT and experienced histopathologists are needed to correctly classify this aggressive disease and discuss the correct management including bone-marrow transplantation where appropriate.
authors: Emmanuelle Ginoux, Fanny Julia, Luc Thomas, Stéphane Dalle, Department of Dermatology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 69002 Lyon, France.
authors: Emmanuelle
authors: E
authors: Ginoux
authors: Emmanuelle Ginoux, Fanny Julia, Luc Thomas, Stéphane Dalle, Department of Dermatology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 69002 Lyon, France.
authors: Fanny
authors: F
authors: Julia
authors: Emmanuelle Ginoux, Fanny Julia, Luc Thomas, Stéphane Dalle, Department of Dermatology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 69002 Lyon, France.
authors: Brigitte
authors: B
authors: Balme
authors: Emmanuelle Ginoux, Fanny Julia, Luc Thomas, Stéphane Dalle, Department of Dermatology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 69002 Lyon, France.
authors: Luc
authors: L
authors: Thomas
authors: Emmanuelle Ginoux, Fanny Julia, Luc Thomas, Stéphane Dalle, Department of Dermatology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, 69002 Lyon, France.
authors: Stéphane
authors: S
authors: Dalle
keywords: Cutaneous lymphoma; Lymphoblastic lymphoma; Skin