title: Chemometric-assisted QuEChERS extraction method for the residual analysis of thiacloprid, spirotetramat and spirotetramat's four metabolites in pepper: Application of their dissipation patterns.
abstract: Chemometric tools equipped with a Plackett-Burman (P-B) design, a central composite design (CCD) and a desirability profile were employed to optimise the QuEChERS (quick, easy, cheap, effective, rugged and safe) method for the quantification of thiacloprid, spirotetramat and spirotetramat's four metabolites in pepper. The average recoveries were in the range of 71.6-119.5%, with relative standard deviations ⩽ 12.1%. The limit of quantification for the method was less than 0.01 mg/kg. The method was applied to field samples to evaluate the residual characteristics of thiacloprid and spirotetramat. The data showed that the first+first-order model is a better fit than the first order model for the dissipation of thiacloprid and spirotetramat in pepper. The half-lives of thiacloprid and spirotetramat in pepper are 0.81 and 1.21 days, respectively. The final residues were between 0.016 mg/kg and 0.13 mg/kg for thiacloprid and 0.08 mg/kg and 0.12 mg/kg for spirotetramat.
authors: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.
authors: Shasha
authors: S
authors: Li
authors: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China. Electronic address: liuxingang@caas.cn.
authors: Xingang
authors: X
authors: Liu
authors: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.
authors: Fengshou
authors: F
authors: Dong
authors: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.
authors: Jun
authors: J
authors: Xu
authors: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.
authors: Hanqing
authors: H
authors: Xu
authors: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.
authors: Mingfeng
authors: M
authors: Hu
authors: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China.
authors: Yongquan
authors: Y
authors: Zheng
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D000073943:Neonicotinoids; D029222:Piper nigrum / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D013843:Thiazines / Q000737:chemistry*
chemical_list: D001372:Aza Compounds; D000073943:Neonicotinoids; D011725:Pyridines; D013141:Spiro Compounds; D013843:Thiazines; C570705:spirotetramat; C417209:thiacloprid
keywords: Dissipation kinetics; Experimental design; Metabolites; Spirotetramat; Thiacloprid