title: In vivo effect of LASSBio-785, a lipid-lowering and anti-inflammatory agent, on cardiac Ca(2+)-ATPases from hypercholesterolemic rats.
authors: Laboratory of Experimental Pharmacology, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil.
authors: Emiliana B
authors: EB
authors: Marques
authors: Laboratory of Experimental Pharmacology, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil.
authors: Nádia A V
authors: NA
authors: Motta
authors: Department of Chemistry, Institute of Exact Sciences, Rural Federal University of Rio de Janeiro UFRRJ, Seropédica, R.J., Brazil.
authors: Arthur E
authors: AE
authors: Kummerle
authors: Laboratory of Evaluation and Synthesis of Bioactive Compounds (LASSBio), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, R.J., Brazil.
authors: Carlos A M
authors: CA
authors: Fraga
authors: Laboratory of Evaluation and Synthesis of Bioactive Compounds (LASSBio), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, R.J., Brazil.
authors: Eliezer J
authors: EJ
authors: Barreiro
authors: Laboratory of Experimental Pharmacology, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil.
authors: Fernanda C F
authors: FC
authors: Brito
authors: Laboratory of Experimental Pharmacology, Department of Physiology and Pharmacology, Fluminense Federal University, Niterói, RJ, Brazil. Electronic address: christiannebretas@vm.uff.br.
authors: Christianne B V
authors: CB
authors: Scaramello
mesh_terms: D000818:Animals; D000252:Calcium-Transporting ATPases / Q000187:drug effects* / Q000378:metabolism; D004195:Disease Models, Animal; D006835:Hydrazones / Q000494:pharmacology*; D006937:Hypercholesterolemia / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D013876:Thiophenes / Q000494:pharmacology*
chemical_list: D006835:Hydrazones; C503362:LASSBio-785; D013876:Thiophenes; D000252:Calcium-Transporting ATPases
keywords: Anti-inflammatory agents; Ca(2+)-ATPase; Hypolipidemic agents; LASSBio-785; N-acylhydrazone derivative