title: Randomized Controlled Trial to Determine the Impact of Probiotic Administration on Colonization With Multidrug-Resistant Organisms in Critically Ill Patients.
abstract: This was a randomized controlled pilot study of Lactobacillus rhamnosus GG versus standard of care to prevent gastrointestinal multidrug-resistant organism colonization in intensive care unit patients. Among 70 subjects, there were no significant differences in acquisition or loss of any multidrug-resistant organisms (P>.05) and no probiotic-associated adverse events.
authors: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors: Jennie H
authors: JH
authors: Kwon
authors: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors: Kerry M
authors: KM
authors: Bommarito
authors: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors: Kimberly A
authors: KA
authors: Reske
authors: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors: Sondra M
authors: SM
authors: Seiler
authors: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors: Tiffany
authors: T
authors: Hink
authors: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors: Hilary M
authors: HM
authors: Babcock
authors: 2Division of Pulmonary and Critical Care Medicine,Washington University School of Medicine,St. Louis,Missouri.
authors: Marin H
authors: MH
authors: Kollef
authors: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors: Victoria J
authors: VJ
authors: Fraser
authors: 3Departments of Pathology & Immunology and Pediatrics,Washington University School of Medicine,St. Louis,Missouri.
authors: Carey-Ann D
authors: CA
authors: Burnham
authors: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors: Erik R
authors: ER
authors: Dubberke
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000517:prevention & control*; D018432:Drug Resistance, Multiple / Q000187:drug effects*; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy / Q000517:prevention & control*; D006785:Hospitals, University; D006801:Humans; D007362:Intensive Care Units; D052201:Lacticaseibacillus rhamnosus; D008297:Male; D008875:Middle Aged; D008923:Missouri; D010865:Pilot Projects; D019936:Probiotics / Q000008:administration & dosage*; D059039:Standard of Care; D016896:Treatment Outcome; D055815:Young Adult