title: Primary Splenic Angiosarcoma: Clinical and Imaging Manifestations of This Rare Aggressive Neoplasm.
abstract: Primary splenic angiosarcoma is a rare and fatal neoplasm arising from vascular endothelial cells within the spleen. With an incidence of 2 cases per 10 million people worldwide, the diagnosis and treatment of this rare entity is unfamiliar and challenging. We describe the case of a previously healthy 45-year-old woman who presented with vague upper-abdominal pain and was found to have a splenic mass on computed tomography. The patient underwent laparoscopic splenectomy and was found to have splenic angiosarcoma on microscopic evaluation. Although specific radiologic diagnosis is not possible, bringing the possibility of primary splenic angiosarcoma to the ordering clinician's attention has the potential to hasten treatment and improve patient outcomes. This case highlights the importance for radiologists to be aware of this rare neoplasm and to consider it in the differential when encountering a heterogeneously enhancing splenic mass.
authors: Department of Radiology, Allegheny Health Network, Pittsburgh, PA. Electronic address: abatouli@wpahs.org.
authors: Ali
authors: A
authors: Batouli
authors: Department of Radiology, Allegheny Health Network, Pittsburgh, PA.
authors: Samuel W
authors: SW
authors: Fairbrother
authors: Department of Pathology, Allegheny Health Network, Pittsburgh, PA.
authors: Jan F
authors: JF
authors: Silverman
authors: Department of Pathology, Allegheny Health Network, Pittsburgh, PA.
authors: Maria De Los Angeles
authors: Mde L
authors: Muniz
authors: Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA.
authors: Kevin B
authors: KB
authors: Taylor
authors: Department of Radiology, Allegheny Health Network, Pittsburgh, PA.
authors: Mark A
authors: MA
authors: Welnick
authors: Department of Surgery, Allegheny Health Network, Pittsburgh, PA.
authors: Sheri A
authors: SA
authors: Mancini
authors: Department of Radiology, Allegheny Health Network, Pittsburgh, PA.
authors: Matthew S
authors: MS
authors: Hartman
mesh_terms: D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006394:Hemangiosarcoma / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D013154:Spleen / Q000000981:diagnostic imaging / Q000601:surgery; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D014057:Tomography, X-Ray Computed / Q000379:methods*