title: Filling the gap: Micro-C accesses the nucleosomal fiber at 100-1000 bp resolution.
abstract: The fine three-dimensional structure of the nucleosomal fiber has remained elusive to genome-wide chromosome conformation capture (3C) approaches. A new study mapping contacts at the single nucleosome level (Micro-C) reveals topological interacting domains along budding yeast chromosomes. These domains encompass one to five consecutive genes and are delimited by highly active promoters.
authors: Theoretical Physics for Condensed Matter Laboratory, UPMC, CNRS UMR 7600, Sorbonne Universités, Place Jussieu, 75005, Paris, France. mozziconacci@lptmc.jussieu.fr.
authors: Julien
authors: J
authors: Mozziconacci
authors: Institut Pasteur, Department Genomes and Genetics, Groupe Régulation Spatiale des Génomes, 75015, Paris, France. romain.koszul@pasteur.fr.|CNRS, UMR 3525, 75015, Paris, France. romain.koszul@pasteur.fr.
authors: Romain
authors: R
authors: Koszul
mesh_terms: D001671:Biochemistry / Q000379:methods*; D015825:Chromosomes, Fungal / Q000737:chemistry*; D009707:Nucleosomes / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000737:chemistry*
chemical_list: D009707:Nucleosomes