title: [Quantitative and qualitative evaluation on tablets of Ginkgo biloba leaves using fingerprint and LC-MS analysis].
abstract: A reasonable method for the quality control of tablets of Ginkgo biloba leaves was established in this paper. The total flavonol glycosides and terpene lactones of G. biloba tablets were quantified by HPLC. Totally, 16 batches of the commercially available tablets of G. biloba leaves were determined. Among of them, 2 batches were unqualified in the content of total flavonol glycosides, and 3 batches were unqualified in the content of terpene lactones. A validated HPLC fingerprint method was established to evaluate the commercially available tablets of G. biloba leaves with the assistance of LC-MS. Sixteen batches showed the similarity of 0.763-0.989. There were 31 fingerprint chromatogram peaks were identified as flavonoids compositions by LC-MS. This provides a research idea for the quality control of tablets of G. biloba leaves.
authors: Wen-lin
authors: WL
authors: Liang
authors: Da-wen
authors: DW
authors: Xie
authors: Gang
authors: G
authors: Ding
authors: Dian-hong
authors: DH
authors: Xu
authors: Yong-cheng
authors: YC
authors: Sun
authors: Lian Yuan-pei
authors: Yan-jing
authors: YJ
authors: Li
authors: Wei
authors: W
authors: Xiao
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D020441:Ginkgo biloba / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods*; D018515:Plant Leaves / Q000737:chemistry; D011786:Quality Control; D013607:Tablets / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal; D013607:Tablets