title: Model for end-stage liver disease-Na score or Maddrey discrimination function index, which score is best?
abstract: OBJECTIVE
  To compare the ability of model for end-stage liver disease (MELD)-Na and Maddrey discrimination function index (DFI) to predict mortality at 30 and 90 d in patients with alcoholic hepatitis (AH).
  
  
  METHODS
  We prospectively assessed 52 patients with AH. Demographic, clinical and laboratory parameters were obtained. MELD-Na and Maddrey DFI were calculated on admission. Short-term mortality was assessed at 30 and 90 d. Receiver operating characteristic curve analysis was performed.
  
  
  RESULTS
  Thirty-day and 90-d mortality was 44% and 58%, respectively. In the univariate analysis, sodium levels was associated with mortality at 30 and 90 d (P = 0.001 and P = 0.03). Child stage, encephalopathy, ascites, or types of treatment were not associated with mortality. MELD-Na was the only predictive factor for mortality at 90 d. For 30-d mortality area under the curve (AUC) was 0.763 (95%CI: 0.63-0.89) for Maddrey DFI and 0.784 for MELD-Na (95%CI: 0.65-0.91, P = 0.82). For 90-d mortality AUC was 0.685 (95%CI: 0.54-0.83) for Maddrey DFI and 0.8710 for MELD-Na (95%CI: 0.76-0.97, P = 0.041).
  
  
  CONCLUSIONS
  AH is associated with high short-term mortality. Our results show that MELD-Na is a more valuable model than DFI to predict short-term mortality.
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: Mercedes
authors: M
authors: Amieva-Balmori
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: Scherezada María Isabel
authors: SM
authors: Mejia-Loza
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: Roberto
authors: R
authors: Ramos-González
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: Felipe
authors: F
authors: Zamarripa-Dorsey
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: Eli
authors: E
authors: García-Ruiz
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: Nuria
authors: N
authors: Pérez Y López
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: Eumir I
authors: EI
authors: Juárez-Valdés
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: Adriana
authors: A
authors: López-Luria
authors: Mercedes Amieva-Balmori, Scherezada María Isabel Mejia-Loza, Roberto Ramos-González, Felipe Zamarripa-Dorsey, Eli García-Ruiz, Nuria Pérez y López, Eumir I Juárez-Valdés, Adriana López-Luria, Servicio de Gastroenterología, Instituto de Investigaciones Médico-Biológicas de la Universidad Veracruzana, Hospital Juárez de México, Ciudad de México 07760, México.
authors: José María
authors: JM
authors: Remes-Troche
keywords: Alcoholic hepatitis; Maddrey; Model for end-stage liver disease-Na; Mortality