title: [Effect of berberine in treating type 2 diabetes mellitus and complications and its relevant mechanisms].
abstract: Berberine (BBR) is a type of alkaloids isolated from Coptidis Rhizoma and Phellodendri Chinensis Cortex and has been used to treat bacterial gastroenteritis, diarrhea and other digestive diseases for more than 1 000 years. According to recent studies, berberine has been found to have multiple pharmacological activities, including lowering blood glucose and lipid, anti-inflammation, antioxidation, relieving type 2 diabetic nephropathy (DN), diabetic cardiovascular disease, diabetic peripheral neuropathy ( DPN) and other complications. In this article, the authors summarized the literature reports about the effects of BBR in lowering blood glucose and preventing and treating the above type 2 diabetes and its complications, in order to provide reference to further studies and promotion of BBR's application.
authors: Qing
authors: Q
authors: Zhang
authors: Yan
authors: Y
authors: Li
authors: Lei
authors: L
authors: Chen
mesh_terms: D000818:Animals; D001599:Berberine / Q000008:administration & dosage*; D001786:Blood Glucose / Q000378:metabolism; D048909:Diabetes Complications / Q000188:drug therapy* / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D006801:Humans
chemical_list: D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D001599:Berberine