title: Analysis of Phospholipid Bilayers on Gold Nanorods by Plasmon Resonance Sensing and Surface-Enhanced Raman Scattering.
abstract: Surface-enhanced Raman scattering (SERS) and localized surface plasmon resonance sensing (LSPR) have been applied for a detailed analysis of lipid bilayers at the surface of gold nanorods. The spatial dependence of surface enhancement and the optical effects of the lipid phase transition confirm the presence of a bilayer membrane structure. Deuterated lipids exchanged rapidly between the nanorod surface and lipid vesicles in solution, suggesting a loosely bound, natural membrane structure. However, at a low solution concentration of lipid vesicles, the lipids on the gold nanorod surface convert to a nonbilayer structure, which could impact biological applications of these nanomaterials.
authors: Department of Physics and Astronomy and ‡Department of Chemistry, Rice University , 6100 Main Street, Houston, Texas 77005, United States.
authors: James R
authors: JR
authors: Matthews
authors: Department of Physics and Astronomy and ‡Department of Chemistry, Rice University , 6100 Main Street, Houston, Texas 77005, United States.
authors: Courtney M
authors: CM
authors: Payne
authors: Department of Physics and Astronomy and ‡Department of Chemistry, Rice University , 6100 Main Street, Houston, Texas 77005, United States.
authors: Jason H
authors: JH
authors: Hafner
mesh_terms: D006046:Gold / Q000737:chemistry*; D008051:Lipid Bilayers / Q000032:analysis*; D043942:Nanotubes / Q000737:chemistry*; D010743:Phospholipids / Q000737:chemistry*; D013059:Spectrum Analysis, Raman / Q000379:methods*; D020349:Surface Plasmon Resonance
chemical_list: D008051:Lipid Bilayers; D010743:Phospholipids; D006046:Gold