title: Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction.
abstract: This paper presents the design, optimization and fabrication of 16 MgO/TiO2 and SiO2/TiO2 based high selective narrow bandpass optical filters. Their performance to extract diffuse reflectance and fluorescence signals from gastrointestinal tissue phantoms was successfully evaluated. The obtained results prove their feasibility to correctly extract those spectroscopic signals, through a Spearman's rank correlation test (Spearman's correlation coefficient higher than 0.981) performed between the original spectra and the ones obtained using those 16 fabricated optical filters. These results are an important step for the implementation of a miniaturized, low-cost and minimal invasive microsystem that could help in the detection of gastrointestinal dysplasia.
authors: Center for Microelectromechanical Systems (CMEMS-UMinho), University of Minho, Campus de Azurém, Guimarães, Portugal.
authors: S
authors: S
authors: Pimenta
authors: INESC Microsistemas e Nanotecnologias (INESC-MN), Lisbon, Portugal.
authors: S
authors: S
authors: Cardoso
authors: International Iberian Nanotechnology Laboratory (INL), Braga, Portugal.
authors: A
authors: A
authors: Miranda
authors: International Iberian Nanotechnology Laboratory (INL), Braga, Portugal.
authors: P
authors: P
authors: De Beule
authors: Centre of Physics (CFUM), University of Minho, Campus de Gualtar, Braga, Portugal.
authors: E M S
authors: EM
authors: Castanheira
authors: Center for Microelectromechanical Systems (CMEMS-UMinho), University of Minho, Campus de Azurém, Guimarães, Portugal.
authors: G
authors: G
authors: Minas
keywords: (120.2230) Fabry-Perot; (170.3890) Medical optics instrumentation; (170.6510) Spectroscopy, tissue diagnostics; (310.1860) Deposition and fabrication; (310.3840) Materials and process characterization