title: Environmental tobacco smoke and the risk of eczema symptoms among school children in South Africa: a cross-sectional study.
abstract: OBJECTIVE
  The aim of this study was to investigate the association between eczema ever (EE) and current eczema symptoms (ES) in relation to exposure to environmental tobacco smoke (ETS).
  
  
  METHODS
  A cross-sectional study using the International Study of Asthma and Allergies in Childhood questionnaire.
  
  
  METHODS
  16 schools were randomly selected from two neighbourhoods situated in Ekurhuleni Metropolitan Municipality, Gauteng Province, South Africa.
  
  
  METHODS
  From a total population of 3764 school children aged 12-14 years, 3468 completed the questionnaire (92% response rate). A total of 3424 questionnaires were included in the final data analysis.
  
  
  METHODS
  The prevalence of EE and current ES was the primary outcome in this study.
  
  
  RESULTS
  Data were analysed using Multilevel Logistic Regression Analysis (MLRA). The likelihood of EE was increased by exposure to ETS at home (OR 1.30 95% CI 1.01 to 1.67) and at school (OR 1.26 95% CI 1.00 to 1.60). The likelihood of EE was lower for males (OR 0.66 95% CI 0.51 to 0.84). The likelihood of ES was increased by ETS at home (OR 1.93 95% CI 1.43 to 2.59) and school (1.44 95% CI 1.09 to 1.90). The likelihood of ES was again lower for males (OR 0.56 95% CI 0.42 to 0.76). Smoking by mother/female guardian increased the likelihood of EE and ES, however, this was not significant in the multivariate analysis.
  
  
  CONCLUSIONS
  Symptoms of eczema were positively associated with exposure to ETS at home and school. The results support the hypothesis that ETS is an important factor in understanding the occurrence of eczema.
authors: Department of Environmental Health, Tshwane University of Technology, Pretoria, South Africa.
authors: Joyce
authors: J
authors: Shirinde
authors: Health Sciences Faculty, School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.
authors: Janine
authors: J
authors: Wichmann
authors: Health Sciences Faculty, School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa.
authors: Kuku
authors: K
authors: Voyi
mesh_terms: D000293:Adolescent; D002648:Child; D003430:Cross-Sectional Studies; D004485:Eczema / Q000453:epidemiology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D012307:Risk Factors; D012574:Schools; D057566:Self Report; D012907:Smoking / Q000453:epidemiology*; D013019:South Africa / Q000453:epidemiology; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
chemical_list: D014028:Tobacco Smoke Pollution
keywords: EPIDEMIOLOGY