title: Features of Metabolic Syndrome and Its Associated Factors during Highly Active Antiretroviral Therapy in Ouagadougou (Burkina Faso).
abstract: BACKGROUND
  To study the features of metabolic syndrome (MS) and its associated factors during highly active antiretroviral therapy (HAART), in Ouagadougou.
  
  
  METHODS
  It was a cross-sectional study from March to November 2011 in Yalgado Ouédraogo hospital. A nonprobability sample of adults receiving antiretroviral drugs for at least 6 months was studied. Pregnancy, ascites, or abdominal mass were noninclusion criteria. Metabolic syndrome met the criteria of International Diabetes Federation 2005.
  
  
  RESULTS
  The authors studied 300 patients. Metabolic syndrome was diagnosed in 54 (18%) patients: mean age 44.8 ± 7.4 years, sex ratio 0.17, and mean duration of HAART 71 ± 30.9 months. The current anomaly of MS was low high-density lipoprotein (HDL)-cholesterol in 37 patients (68.5%), and the common profile of MS was high waist circumference + low HDL-cholesterol + abnormal blood pressure (29.6%). Associated factors were protease inhibitor regimens (P = .000), female gender (P = .004), age > 42 years (P = .001), and lipodystrophy (P = .01).
  
  
  CONCLUSIONS
  Cardiovascular risks should be regarded during the care of HIV-infected patients.
authors: Unité de formation et de recherche en sciences de la santé, Université de Ouagadougou, Ouagadougou, Burkina Faso Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso oumgui@yahoo.fr.
authors: Oumar
authors: O
authors: Guira
authors: Unité de formation et de recherche en sciences de la santé, Université de Ouagadougou, Ouagadougou, Burkina Faso Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: Hervé
authors: H
authors: Tiéno
authors: Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: Arnaud Eric
authors: AE
authors: Diendéré
authors: Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: Yempabou
authors: Y
authors: Sagna
authors: Unité de formation et de recherche en sciences de la santé, Université de Ouagadougou, Ouagadougou, Burkina Faso Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: Ismael
authors: I
authors: Diallo
authors: Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: Bertille
authors: B
authors: Yaméogo
authors: Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: Lassané
authors: L
authors: Zoungrana
authors: INSSA, Université Polytechnique de Bobo-Dioulasso, Bobo-Dioulasso, Burkina Faso.
authors: Tènè Marceline
authors: TM
authors: Yaméogo
authors: Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: Réné
authors: R
authors: Bognounou
authors: Unité de formation et de recherche en sciences de la santé, Université de Ouagadougou, Ouagadougou, Burkina Faso Service de médecine interne, Centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: Joseph Youssouf
authors: JY
authors: Drabo
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000009:adverse effects*; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D002050:Burkina Faso / Q000453:epidemiology; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000209:etiology* / Q000378:metabolism; D008875:Middle Aged; D012307:Risk Factors
chemical_list: D019380:Anti-HIV Agents
keywords: Burkina Faso; HAART; HIV/AIDS; metabolic syndrome