title: Tragacanth gum as a natural polymeric wall for producing antimicrobial nanocapsules loaded with plant extract.
abstract: Tragacanth gum as a biocompatible and biodegradable polymer with good properties including emulsifying, viscosity and cross-linking ability can be used as the wall material in encapsulation of different compounds, specifically plant extracts. In this paper, for the first time, Tragacanth gum was used to produce nanocapsules containing plant extract through microemulsion method. The effect of different parameters on the average size of prepared nanocapsules in presence of aluminum and calcium chloride through ultrasonic and magnetic stirrer was investigated. The high efficient nanocapsules were prepared with spherical shape and smooth surface. The average size of nanocapsules prepared through ultrasonic using aluminum chloride (22nm) was smaller than other products. The structure of prepared nanocapsules was studied by FT-IR spectroscopy. Antimicrobial activity of different nanocapsules against Escherichia coli, Staphylococcus aureus and Candida albicans was investigated by shake flask method during their release showed 100% microbial reduction after 12h stirring.
authors: Textile Engineering Department, Functional Fibrous Structures & Environmental Enhancement (FFSEE), Amirkabir University of Technology, Tehran, Iran.
authors: Soraya
authors: S
authors: Ghayempour
authors: Textile Engineering Department, Functional Fibrous Structures & Environmental Enhancement (FFSEE), Amirkabir University of Technology, Tehran, Iran. Electronic address: tex5mm@aut.ac.ir.
authors: Majid
authors: M
authors: Montazer
authors: Skin Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors: Mahnaz
authors: M
authors: Mahmoudi Rad
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D000935:Antifungal Agents / Q000008:administration & dosage; D036142:Mentha piperita; D008826:Microbial Sensitivity Tests; D053769:Nanocapsules / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D010936:Plant Extracts / Q000008:administration & dosage*; D010938:Plant Oils / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D014144:Tragacanth / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D053769:Nanocapsules; D010936:Plant Extracts; D010938:Plant Oils; D011108:Polymers; D014144:Tragacanth; C015424:peppermint oil
keywords: Encapsulation; Microemulsion; Nanocapsules; Peppermint oil; Tragacanth gum