title: Profound hypotony maculopathy in a first episode of bilateral idiopathic acute anterior uveitis.
abstract: BACKGROUND
  We report a case of a HLA-B27 negative patient presenting with severe, bilateral, idiopathic acute anterior uveitis with acute hypotony and hypotony maculopathy as their first uveitic episode.
  
  
  METHODS
  Within a week of onset of her first episode of acute anterior uveitis, a 45 year-old Caucasian lady developed profound ocular hypotony with unrecordable intraocular pressures, reduced vision and choroidal folds. All investigations were negative. Uveitic hypotony responded slowly to corticosteroids--intravenous, oral and topical--with normalization of intraocular pressure and resolution of choroidal folds after two months. Anterior uveitis and hypotony have not returned with six months of follow-up.
  
  
  CONCLUSIONS
  Bilateral, profound hypotony maculopathy may present acutely in idiopathic acute anterior uveitis, may be slow to respond to treatment and should be considered as a cause of vision loss in patients with this condition.
authors: Academic Unit of Ophthalmology, University of Birmingham, Birmingham & Midland Eye Centre, Dudley Road, Birmingham, B18 7QH, UK. m.r.edmunds@bham.ac.uk.|Hereford County Hospital, Stonebow Road, Hereford, HR1 2BN, UK. m.r.edmunds@bham.ac.uk.
authors: Matthew R
authors: MR
authors: Edmunds
authors: Hereford County Hospital, Stonebow Road, Hereford, HR1 2BN, UK. simon.madge@wvt.nhs.uk.
authors: Simon N
authors: SN
authors: Madge
mesh_terms: D000208:Acute Disease; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D015796:HLA-B27 Antigen / Q000276:immunology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008875:Middle Aged; D015814:Ocular Hypotension / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014065:Tonometry, Ocular; D014606:Uveitis, Anterior / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014792:Visual Acuity / Q000502:physiology
chemical_list: D005938:Glucocorticoids; D015796:HLA-B27 Antigen