title: Prognosis of ultra-early microsurgery combined with extraventricular drainage in patients with poor-grade aneurysms.
abstract: OBJECTIVE
  To explore the clinical effects of ultra-early microsurgery (< 24 hours) combined with extraventricular drainage for the treatment of poor-grade aneurysms.
  
  
  METHODS
  A total of 60 patients with poor-grade aneurysms were randomly divided into a microsurgery combined with extraventricular drainage (MED) group and conventional microsurgery (M) group. The prognosis was comparatively studied for these 2 groups.
  
  
  RESULTS
  All patients underwent a Glasgow Outcome Scale (GOS) assessment during a 6-month to 2-year follow-up. The excellent recovery (GOS, 4-5 points) rate for the MED group was 30% higher than that of the M group, while the poor recovery (GOS, 1-2 points) rate was 26.7% lower than that of the M group (P = 0.016). The incidence of acute brain swelling (26.7% vs 53.3%; P = 0.035), cerebral infarction (20% vs 46.7%; P = 0.025), and vasospasm (16.7% vs 40%; P = 0.045) for the MED group was significantly lower than that of the M group.
  
  
  CONCLUSIONS
  For microsurgery combined with extraventricular drainage, the risk of cerebral infarction and vasospasm were significantly reduced for patients with poor-grade aneurysms, and the prognosis was better.
authors: Department of Neurosurgery, 101 Hospital of PLA Wuxi 214044, China.
authors: Jian-Qing
authors: JQ
authors: He
authors: Department of Neurosurgery, Wuxi Clinical Medical School, Anhui Medical University, 101 Hospital of PLA Wuxi 214044, China.
authors: Jun-Hui
authors: JH
authors: Chen
authors: Department of Neurosurgery, 101 Hospital of PLA Wuxi 214044, China.
authors: Jun
authors: J
authors: Zhu
authors: Department of Neurosurgery, 101 Hospital of PLA Wuxi 214044, China.
authors: Lei
authors: L
authors: Chen
authors: Department of Neurosurgery, 101 Hospital of PLA Wuxi 214044, China.
authors: Chun-Lei
authors: CL
authors: Zhang
authors: Department of Neurosurgery, 101 Hospital of PLA Wuxi 214044, China.
authors: Li-Kun
authors: LK
authors: Yang
authors: Department of Neurosurgery, 101 Hospital of PLA Wuxi 214044, China.
authors: Yu-Hai
authors: YH
authors: Wang
authors: Department of Otolaryngological, 92 Hospital of PLA Nanping 353000, China.
authors: Jun
authors: J
authors: Zou
authors: Department of Neurosurgery, 101 Hospital of PLA Wuxi 214044, China.
authors: Xu
authors: X
authors: Hu
keywords: Microsurgery; cerebral infarction; extraventricular drainage; poor-grade aneurysm; vasospasm