title: CD192 gene variant and susceptibility to cervical cancer: a meta analysis.
abstract: BACKGROUND
  Several molecular epidemiological studies have explored the association between G46295A variant of CD192 gene and cervical cancer susceptibility in distinct populations. However, the results are contradictory. To provide convincing evidence for the association, we performed the present meta-analysis incorporating all case-control studies.
  
  
  RESULTS
  The Cochrane, Google Scholar and PubMed databases were systematically searched to identify the potentially relevant studies. Statistical analyses were performed using R software. Crude odds ratio (OR) was calculated to estimate the risk of cervical cancer. Five case-control studies were considered in the final analysis. Using the homozygous, heterogeneous, allele, dominant, and recessive model, we found the association between CD192 G46295A variant and cervical cancer was not statistically significant.
  
  
  CONCLUSIONS
  This meta-analysis shows that the CD192 G46295A variant may not confer genetic susceptibility towards cervical cancer.
authors: Department of Oncology, Jiulongpo District Hospital of Traditional Chinese Medicine in Chongqing City Chongqing, China ; College of Bio-Information, Chongqing University of Posts and Telecommunications Chongqing, China.
authors: Yuying
authors: Y
authors: Chen
authors: Department of Obstetrics and Gynecology, 263 Clinical of the General Hospital of Beijing Military Area Beijing 101149, China.
authors: Xinli
authors: X
authors: Liu
authors: Department of Oncology, Jiulongpo District Hospital of Traditional Chinese Medicine in Chongqing City Chongqing, China.
authors: Min
authors: M
authors: Chen
authors: Department of Oncology, Jiulongpo District Hospital of Traditional Chinese Medicine in Chongqing City Chongqing, China.
authors: Jian
authors: J
authors: Shen
authors: Department of Oncology, Jiulongpo District Hospital of Traditional Chinese Medicine in Chongqing City Chongqing, China.
authors: Yanqi
authors: Y
authors: Lu
authors: Department of Infectious Disease, The Fourth Hospital of Harbin Medical University Harbin 150001, Heilongjiang, China.
authors: Lei
authors: L
authors: Yu
authors: Department of Orthopedics, 253 Hospital of Chinese PLA Huhhot 010050, China.
authors: Shouying
authors: S
authors: Liu
keywords: CD192; cervical cancer; polymorphism