title: Shockingly Early: Chromatin-Mediated Loss of the Heat Shock Response.
abstract: In this issue of Molecular Cell, Labbadia and Morimoto (2015) show that there is a precipitous decline in stress resistance at the onset of reproduction in C. elegans and that this transition is regulated by changes in repressive chromatin marks.
authors: Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA.
authors: Lauren N
authors: LN
authors: Booth
authors: Department of Genetics, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA; Glenn Laboratories for the Biology of Aging, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA. Electronic address: abrunet1@stanford.edu.
authors: Anne
authors: A
authors: Brunet
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D018869:Heat-Shock Response