title: Gender-specific total knee arthroplasty in Singaporean women.
abstract: OBJECTIVE
  To compare the outcome of 145 women who underwent conventional total knee arthroplasty (TKA) with 77 women who underwent gender-specific TKA.
  
  
  METHODS
  Records of 222 women who underwent primary TKA using a conventional (n=145) or gender-specific (n=77) size E or F prosthesis for end-stage osteoarthritis were reviewed. The gender-specific prosthesis has a narrower mediolateral dimension. Patients were assessed for flexion, Oxford Knee Score, Knee Society function and knee scores, and Short Form-36 Health Survey preoperatively and postoperatively (at 6 months and 2 years).
  
  
  RESULTS
  The 2 groups were comparable in terms of age (67.8 vs. 68.1 years, p=0.789), body mass index (28.6 vs. 27.8 kg/m(2), p=0.189), and preoperative scores. 12 women with conventional TKA and 4 women with gender-specific TKA were lost to followup. Compared with women with conventional TKA, women with gender-specific TKA had better flexion at 6 months (116° vs. 121.9°, p=0.007) and 2 years (118.7° vs. 124.6°, p=0.006), better bodily pain score at 2 years (65.1 vs. 72.4, p=0.049), and greater improvement in bodily pain score from baseline to 2 years (30 vs. 38.5, p=0.034).
  
  
  CONCLUSIONS
  Gender-specific TKA enables better knee flexion and less bodily pain in women who have a high propensity to develop mediolateral overhang of the femoral component.
authors: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors: Jason Beng Teck
authors: JB
authors: Lim
authors: Department of Physiotherapy, Singapore General Hospital, Singapore.
authors: Hwei Chi
authors: HC
authors: Chong
authors: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors: Kevin
authors: K
authors: Ling
authors: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors: Amanda
authors: A
authors: Teo
authors: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors: Seng Jin
authors: SJ
authors: Yeo
authors: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors: Shi-Lu
authors: SL
authors: Chia
authors: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors: Pak Lin
authors: PL
authors: Chin
authors: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors: Darren
authors: D
authors: Tay
authors: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors: Ngai Nung
authors: NN
authors: Lo
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology / Q000601:surgery*; D007720:Knee Prosthesis; D008297:Male; D020370:Osteoarthritis, Knee / Q000453:epidemiology / Q000601:surgery*; D011184:Postoperative Period; D015995:Prevalence; D016059:Range of Motion, Articular; D012737:Sex Factors; D012846:Singapore / Q000453:epidemiology
keywords: arthroplasty, replacement, knee; treatment outcome