title: One-Year Angiographic Follow-Up after WEB-SL Endovascular Treatment of Wide-Neck Bifurcation Intracranial Aneurysms.
abstract: OBJECTIVE
  Endovascular coiling of wide-neck intracranial aneurysms is associated with low rates of initial angiographic occlusion and high rates of recurrence. The WEB intrasaccular device has been developed specifically for this indication. To date, there has been no report of the long-term follow-up of a series of patients with aneurysms treated with this type of device, to our knowledge. Our aim was to evaluate a 1-year follow-up of angiographic results in a prospective single-center series of patients treated with the WEB-Single-Layer (SL) device.
  
  
  METHODS
  All patients treated with the WEB-SL device in our center between August 2013 and May 2014 were prospectively included. One-year angiographic outcomes were assessed. Results at follow-up were graded as complete occlusion, neck remnant, or residual aneurysm.
  
  
  RESULTS
  Eight patients with 8 unruptured wide-neck aneurysms were enrolled in this study. Average dome width was 7.5 mm (range, 5.4-10.7 mm), and average neck size was 4.9 mm (range, 2.6-6.5 mm). One-year angiographic follow-up obtained in all aneurysms included 1 complete aneurysm occlusion (12.5%), 6 neck remnants (75%), and 1 aneurysm remnant (12.5%). Of 8 aneurysms, worsening of aneurysm occlusion was observed in 2 (25%) by compression of the WEB device. There was no angiographic recurrence of initially totally occluded aneurysms. No bleeding was observed during the follow-up period.
  
  
  CONCLUSIONS
  Endovascular therapy of intracranial aneurysms with the WEB-SL device allows treatment of wide-neck aneurysms with a high rate of neck remnant at 1 year, at least partially explained by WEB compression. Initial size selection and technologic improvements could be an option for optimization of aneurysm occlusion in WEB-SL treatment.
authors: From the DHU IRIS, Departments of Interventional Neuroradiology (R.S.-H., B.G., R.R., P.-E.L., I.E., U.G.-S., F.T.).
authors: R
authors: R
authors: Sivan-Hoffmann
authors: From the DHU IRIS, Departments of Interventional Neuroradiology (R.S.-H., B.G., R.R., P.-E.L., I.E., U.G.-S., F.T.) benjamin.gory@chu-lyon.fr.
authors: B
authors: http://orcid.org/0000-0001-8424-4464
authors: B
authors: Gory
authors: From the DHU IRIS, Departments of Interventional Neuroradiology (R.S.-H., B.G., R.R., P.-E.L., I.E., U.G.-S., F.T.).
authors: R
authors: http://orcid.org/0000-0002-1520-2057
authors: R
authors: Riva
authors: From the DHU IRIS, Departments of Interventional Neuroradiology (R.S.-H., B.G., R.R., P.-E.L., I.E., U.G.-S., F.T.).
authors: P-E
authors: http://orcid.org/0000-0002-2536-6338
authors: PE
authors: Labeyrie
authors: Neurosurgery (F.S.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France.
authors: F
authors: F
authors: Signorelli
authors: From the DHU IRIS, Departments of Interventional Neuroradiology (R.S.-H., B.G., R.R., P.-E.L., I.E., U.G.-S., F.T.).
authors: I
authors: I
authors: Eldesouky
authors: From the DHU IRIS, Departments of Interventional Neuroradiology (R.S.-H., B.G., R.R., P.-E.L., I.E., U.G.-S., F.T.).
authors: U
authors: U
authors: Gonike-Sadeh
authors: Hospices Civils de Lyon (X.A.), Délégation à la Recherche Clinique et à l'Innovation, Cellule Innovation/UMR-CNRS 5510/MATEIS, Lyon, France.
authors: X
authors: X
authors: Armoiry
authors: From the DHU IRIS, Departments of Interventional Neuroradiology (R.S.-H., B.G., R.R., P.-E.L., I.E., U.G.-S., F.T.).
authors: F
authors: http://orcid.org/0000-0001-5006-2320
authors: F
authors: Turjman
mesh_terms: D000328:Adult; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012008:Recurrence; D016896:Treatment Outcome