title: Acute disseminated encephalomyelitis following inactivated influenza vaccination in the Brazilian Amazon: a case report.
abstract: Here, we describe a case of acute disseminated encephalomyelitis (ADEM) that occurred during a plausible risk interval following inactivated influenza vaccination in a previously healthy 27-year-old man from Manaus, Brazil. He was treated with intravenous methylprednisolone and immunoglobulin. One-month follow-up revealed resolution of the brain lesions, but not of the spinal cord lesions. No recurrence or progression of the main neurological symptoms was observed. After two years of monitoring, the patient continues to experience weak lower limbs and urinary retention. Thus, we recommend that ADEM should be considered in a patient presenting with neurological symptoms after influenza vaccination.
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Solange Dourado de
authors: SD
authors: Andrade
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Maria Graciede Filha Santarém
authors: MG
authors: Andrade
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Pablo José
authors: PJ
authors: Santos
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Maria de Lourdes
authors: Mde L
authors: Galvão
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Mariana Martins de
authors: MM
authors: Barros
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Rajendranath
authors: R
authors: Ramasawmy
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Izabella Picinin
authors: IP
authors: Safe
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Wuelton Marcelo
authors: WM
authors: Monteiro
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Meritxell
authors: M
authors: Sabidó
authors: Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
authors: Maria das Graças Costa
authors: Md
authors: Alecrim
mesh_terms: D000328:Adult; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D008297:Male
chemical_list: D007252:Influenza Vaccines