title: How does the hippocampus shape decisions?
abstract: Making optimal decisions depends on an appreciation of the value of choices. An important source of information about value comes from memory for prior experience. Such value-based learning has historically been considered the domain of a striatal memory system. However, recent developments suggest that memorial representations supported by the hippocampus may also contribute to decision making. Unlike striatal representations, hippocampal ones are flexible; they can be modified and updated as new information is acquired. In this paper we argue that the hippocampus plays a pivotal role in value-based decision making via three flexible learning mechanisms: (1) updating, (2) generalization, and (3) construction.
authors: VA Boston Healthcare System, 150 South Huntington Ave (151A), Boston, MA 02130, United States; Boston University School of Medicine, Department of Psychiatry, 72 E Concord St, Boston, MA 02118, United States. Electronic address: palombo@bu.edu.
authors: Daniela J
authors: DJ
authors: Palombo
authors: Wellesley College, Department of Psychology, 106 Central St, Wellesley, MA 02481, United States; VA Boston Healthcare System, 150 South Huntington Ave (151A), Boston, MA 02130, United States; Boston University School of Medicine, Department of Psychiatry, 72 E Concord St, Boston, MA 02118, United States.
authors: Margaret M
authors: MM
authors: Keane
authors: VA Boston Healthcare System, 150 South Huntington Ave (151A), Boston, MA 02130, United States; Boston University School of Medicine, Department of Psychiatry, 72 E Concord St, Boston, MA 02118, United States.
authors: Mieke
authors: M
authors: Verfaellie
mesh_terms: D003657:Decision Making / Q000502:physiology*; D005793:Generalization, Psychological / Q000502:physiology; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D007858:Learning / Q000502:physiology*; D008568:Memory / Q000502:physiology
keywords: Decision making; Hippocampus; Value