title: Effects of an evidence-based computerized virtual clinician on low-density lipoprotein and non-high-density lipoprotein cholesterol in adults without cardiovascular disease: The Interactive Cholesterol Advisory Tool.
abstract: There is a lack of research on the use of electronic tools that guide patients toward reducing their cardiovascular disease risk. We conducted a 9-month clinical trial in which participants who were at low (n = 100) and moderate (n = 23) cardiovascular disease risk-based on the National Cholesterol Education Program III's 10-year risk estimator-were randomized to usual care or to usual care plus use of an Interactive Cholesterol Advisory Tool during the first 8 weeks of the study. In the moderate-risk category, an interaction between treatment condition and Framingham risk estimate on low-density lipoprotein and non-high-density lipoprotein cholesterol was observed, such that participants in the virtual clinician treatment condition had a larger reduction in low-density lipoprotein and non-high-density lipoprotein cholesterol as their Framingham risk estimate increased. Perceptions of the Interactive Cholesterol Advisory Tool were positive. Evidence-based information about cardiovascular disease risk and its management was accessible to participants without major technical challenges.
authors: University of Rochester, USA robert_block@urmc.rochester.edu.|Self-Determined Health, Inc., USA robert_block@urmc.rochester.edu.|University of Rochester, USA robert_block@urmc.rochester.edu.
authors: Robert C
authors: RC
authors: Block
authors: University of Rochester, USA.|Self-Determined Health, Inc., USA.|University of Rochester, USA.
authors: Amir
authors: A
authors: Abdolahi
authors: University of Rochester, USA.
authors: Christopher P
authors: CP
authors: Niemiec
authors: Self-Determined Health, Inc., USA.
authors: C Scott
authors: CS
authors: Rigby
authors: University of Rochester, USA.
authors: Geoffrey C
authors: GC
authors: Williams
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000517:prevention & control / Q000628:therapy; D003661:Decision Support Techniques; D004867:Equipment Design / Q000592:standards*; D055317:Evidence-Based Practice / Q000379:methods*; D005260:Female; D006801:Humans; D008077:Lipoproteins, LDL / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D063731:Mobile Applications / Q000592:standards*; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D011795:Surveys and Questionnaires
chemical_list: D008077:Lipoproteins, LDL
keywords: cardiovascular disease; cardiovascular disease risk; low-density lipoprotein cholesterol; non-high-density lipoprotein cholesterol; virtual clinician