title: Erythromelalgia with a linear pattern in a 12-year-old girl.
abstract: Erythromelalgia is a rare clinical syndrome characterized by erythema, increased temperature, and severe burning pain that can be aggravated by warmth or relieved by cold. Erythromelalgia occurs either as a primary, idiopathic form, or secondary to a number of diseases and conditions. Although fairly well studied in adults, the characteristics, pathogenesis, and natural history are poorly characterized in the pediatric age group. Different therapeutic options have been tried, but no optimal treatment has been suggested for erythromelalgia. We report a rare case of linear erythromelalgia in a 12-year-old girl involving her central body from the peripheral extremities, which seemed to be secondary due to vasculitis. Clinical progress waxed and waned on maintenance aspirin and propranolol.
authors: Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
authors: Seokwon
authors: S
authors: Huh
authors: Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
authors: Mo Kyung
authors: MK
authors: Jung
authors: Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
authors: Lucy Youngmin
authors: http://orcid.org/0000-0002-4577-3168
authors: LY
authors: Eun
authors: Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
authors: Jo Won
authors: JW
authors: Jung
authors: Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
authors: Jae Young
authors: JY
authors: Choi
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use*; D002648:Child; D004359:Drug Therapy, Combination; D004916:Erythromelalgia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D010146:Pain / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011433:Propranolol / Q000627:therapeutic use*; D014657:Vasculitis / Q000150:complications* / Q000188:drug therapy
chemical_list: D000319:Adrenergic beta-Antagonists; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011433:Propranolol; D001241:Aspirin
keywords: autoimmune; child; erythromelalgia; sodium channelopathy; vasculitis