title: [Clinical study of anti-Mullerian hormone in prediction of ovarian aging].
abstract: OBJECTIVE
  To explore the serum anti-Mullerian hormone (AMH) level in women of childbearing age with normal menstrual cycles.
  
  
  METHODS
  A total of 1 423 women with regular menstrual cycles were selected and divided into 5 groups according to their ages, i.e. ≤ 25, 26-30, 31-35, 36-40, ≥ 41 years. Their serum levels of AMH were measured, and the relationship between AMH and age was analyzed.
  
  
  RESULTS
  The serum AMH levels of 5 groups according to ages (≤ 25, 26-30, 31-35, 36-40, ≥ 41 years) were 3.62, 3.10, 2.27, 1.07, 0.45 µg/L, respectively. The comparison of serum AMH levels in different age groups had significant difference (P < 0.01). Serum AMH level declined with increasing age, and dropped significantly after 36. The serum AMH level and age showed a negative correlation with significant difference (r = -0.374, P < 0.01). Quadratic regression of logAMH proximally reflected the relationship between AMH and age.
  
  
  CONCLUSIONS
  AMH determination for women of childbearing age could provide reference for the evaluation of ovarian function.
authors: Department of Obstetrics and Gynecology, Jiaxing Maternity and Child Health Care Hospital, Jiaxing 314000, China.
authors: Lihong
authors: L
authors: Gao
authors: Wenwei
authors: W
authors: Cai
authors: Qin
authors: Q
authors: Zhu
authors: Yongxiang
authors: Y
authors: Li
authors: Qianyan
authors: Q
authors: Jin
authors: Meiguang
authors: M
authors: Zhang
authors: Yingru
authors: Y
authors: Cai
authors: Zhiting
authors: Z
authors: Zhou
authors: 314000 Department of Obstetrics and Gynecology, Jiaxing University; Email: 13732574145@163.com.
authors: Xiaojie
authors: X
authors: Wu
mesh_terms: D000328:Adult; D000375:Aging / Q000502:physiology*; D054304:Anti-Mullerian Hormone / Q000097:blood*; D015415:Biomarkers / Q000378:metabolism; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D010053:Ovary / Q000502:physiology*
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone