title: Patient-Specific CT-Based Instrumentation versus Conventional Instrumentation in Total Knee Arthroplasty: A Prospective Randomized Controlled Study on Clinical Outcomes and In-Hospital Data.
abstract: Total knee arthroplasty (TKA) is a frequently performed procedure in orthopaedic surgery. Recently, patient-specific instrumentation was introduced to facilitate correct positioning of implants. The aim of this study was to compare the early clinical results of TKA performed with patient-specific CT-based instrumentation and conventional technique. A prospective, randomized controlled trial on 112 patients was performed between January 2011 and December 2011. A group of 112 patients who met the inclusion and exclusion criteria were enrolled in this study and randomly assigned to an experimental or control group. The experimental group comprised 52 patients who received the Signature CT-based implant positioning system, and the control group consisted of 60 patients with conventional instrumentation. Clinical outcomes were evaluated with the KSS scale, WOMAC scale, and VAS scales to assess knee pain severity and patient satisfaction with the surgery. Specified in-hospital data were recorded. Patients were followed up for 12 months. At one year after surgery, there were no statistically significant differences between groups with respect to clinical outcomes and in-hospital data, including operative time, blood loss, hospital length of stay, intraoperative observations, and postoperative complications. Further high-quality investigations of various patient-specific systems and longer follow-up may be helpful in assessing their utility for TKA.
authors: Department of Orthopedic Surgery and Traumatology, Central Research Hospital of Ministry of Interior, Wołoska 137, 02-507 Warsaw, Poland ; Department of Orthopaedics and Traumatology of Musculoskeletal System, 1st Faculty of Medicine, Medical University of Warsaw, ul. Lindleya 4, 02-005 Warsaw, Poland.
authors: Andrzej
authors: A
authors: Kotela
authors: Department of Orthopedic Surgery and Traumatology, Central Research Hospital of Ministry of Interior, Wołoska 137, 02-507 Warsaw, Poland.
authors: Jacek
authors: J
authors: Lorkowski
authors: School of Medicine with the Division of Dentistry in Zabrze, Chair and Department of Descriptive and Topographic Anatomy, Medical University of Silesia, ul. Jordana 19, 41-808 Zabrze, Poland.
authors: Marek
authors: M
authors: Kucharzewski
authors: Department of Kinesiotherapy and Manual Therapy, Faculty of Health Sciences, Vincent Pol University in Lublin, ul. Choiny 2, 20-816 Lublin, Poland.
authors: Magdalena
authors: M
authors: Wilk-Frańczuk
authors: Head of Institute of Physiotherapy, The Jan Kochanowski University of Humanities and Sciences, al. IX Wieków 19, 25-317 Kielce, Poland.
authors: Zbigniew
authors: Z
authors: Śliwiński
authors: Department of Physiotherapy, Faculty of Health and Medicine Science, Andrzej Frycz Modrzewski Cracow University, ul. Gustawa Herling Grudzińskiego 1, 30-705 Kraków, Poland.
authors: Bogusław
authors: B
authors: Frańczuk
authors: Department of Orthopaedics and Traumatology of Musculoskeletal System, 1st Faculty of Medicine, Medical University of Warsaw, ul. Lindleya 4, 02-005 Warsaw, Poland.
authors: Paweł
authors: P
authors: Łęgosz
authors: Department of Orthopedic Surgery and Traumatology, Central Research Hospital of Ministry of Interior, Wołoska 137, 02-507 Warsaw, Poland ; Department of Physiotherapy, The Jan Kochanowski University of Humanities and Sciences, al. IX Wieków 19, 25-317 Kielce, Poland.
authors: Ireneusz
authors: I
authors: Kotela
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology / Q000601:surgery*; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*; D017060:Patient Satisfaction; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome