title: Rhodium Catalyzed Asymmetric Hydrogenation of 2-Pyridine Ketones.
abstract: Catalyzed by [Rh(COD)Binapine]BF4, the asymmetric hydrogenation of 2-pyridine ketones has been achieved with excellent enantioselectivities (enantiomeric excesses up to 99%) under mild conditions. This method is suitable for various kinds of 2-pyridine ketones and their derivatives. A number of enantiomerically pure chiral 2-pyridine-aryl/alkyl alcohols were prepared through hydrogenation, which can be used directly in organic synthesis.
authors: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors: Hailong
authors: H
authors: Yang
authors: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors: Ningning
authors: N
authors: Huo
authors: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors: Ping
authors: P
authors: Yang
authors: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors: Hao
authors: H
authors: Pei
authors: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors: Hui
authors: H
authors: Lv
authors: Key Laboratory of Biomedical Polymers of Ministry of Education & College of Chemistry and Molecular Sciences, Wuhan University , Wuhan, Hubei 430072, China.
authors: Xumu
authors: X
authors: Zhang