title: Acupuncture for Functional Dyspepsia: A Single Blinded, Randomized, Controlled Trial.
abstract: In order to investigate the therapeutic potential of acupuncture on patients with functional dyspepsia (FD), patients were randomized to receive acupuncture at classic acupoints with manipulations (treatment group) versus acupuncture at nonacupoints without manipulation (control group) once every other day, three times a week, for one month and were followed up for three months. The primary outcomes included dyspeptic symptoms, quality of life, and mental status. The secondary outcomes included the fasting serum gastrin concentration, and frequency and propagation velocity of gastric slow waves. Sixty patients with FD were included, among whom, four dropped out. After one month's treatment, patients with FD showed significant improvements in primary (in both groups) and secondary (in the eight patients of the treatment group) outcomes as compared with baseline (P = 0.0078 to <0.0001); treatment group has better outcomes in all primary outcome measures (P < 0.0001 except for SDS (P = 0.0005)). Improvements on dyspeptic symptoms persist during follow-up (better in the treatment group). Acupuncture with manual manipulation had better effects on improving dyspeptic symptoms, mental status, and quality of life in patients with FD. These effects may be related to the increased frequency and propagation speed of gastric slow waves and serum gastrin secretion.
authors: Department of Acupuncture and Moxibustion, Guang An Men Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053, China ; Department of Radiology, Guang An Men Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
authors: Yulian
authors: Y
authors: Jin
authors: Department of Radiology, Guang An Men Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
authors: Qing
authors: Q
authors: Zhao
authors: Department of Health Care Studies, Daemen College, Amherst, NY 14226, USA.
authors: Kehua
authors: K
authors: Zhou
authors: Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors: Xianghong
authors: X
authors: Jing
authors: Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors: Xiaochun
authors: X
authors: Yu
authors: Department of Radiology, Guang An Men Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
authors: Jiliang
authors: J
authors: Fang
authors: Department of Acupuncture and Moxibustion, Guang An Men Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053, China.
authors: Zhishun
authors: Z
authors: Liu
authors: Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors: Bing
authors: B
authors: Zhu