title: Pulp response to high fluoride releasing glass ionomer, silver diamine fluoride, and calcium hydroxide used for indirect pulp treatment: An in-vivo comparative study.
abstract: OBJECTIVE
  The study aims at determining pulp response of two high fluoride releasing materials silver diamine fluoride (SDF) and Type VII glass ionomer cement (GIC) when used as indirect pulp treatment (IPT) materials.
  
  
  METHODS
  Deep Class V cavities were made on four first premolars indicated for extraction for orthodontic reasons. SDF, Type VII GIC, and calcium hydroxide base are given in three premolars, and one is kept control. Premolars were extracted 6 weeks after the procedure and subjected to histopathological examination to determine the pulp response. The results were analyzed using Chi-square test.
  
  
  RESULTS
  No inflammatory changes were observed in any of the groups. Significantly more number of specimens in SDF and Type VII GIC groups showed tertiary dentin deposition (TDD) when compared to control group. No significant difference was seen in TDD when intergroup comparison was made. Odontoblasts were seen as short cuboidal cells with dense basophilic nucleus in SDF and Type VII GIC group.
  
  
  CONCLUSIONS
  The study demonstrated TDD inducing ability of SDF and Type VII GIC and also established the biocompatibility when used as IPT materials.
authors: Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
authors: Atish
authors: A
authors: Korwar
authors: Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
authors: Sidhartha
authors: S
authors: Sharma
authors: Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
authors: Ajay
authors: A
authors: Logani
authors: Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.
authors: Naseem
authors: N
authors: Shah
keywords: Calcium hydroxide; high fluoride releasing glass ionomer; indirect pulp treatment; pulpal response; silver diamine fluoride