title: Wave trains induced by circularly polarized electric fields in cardiac tissues.
abstract: Clinically, cardiac fibrillation caused by spiral and turbulent waves can be terminated by globally resetting electric activity in cardiac tissues with a single high-voltage electric shock, but it is usually associated with severe side effects. Presently, a promising alternative uses wave emission from heterogeneities induced by a sequence of low-voltage uniform electric field pulses. Nevertheless, this method can only emit waves locally near obstacles in turbulent waves and thereby requires multiple obstacles to globally synchronize myocardium and thus to terminate fibrillation. Here we propose a new approach using wave emission from heterogeneities induced by a low-voltage circularly polarized electric field (i.e., a rotating uniform electric field). We find that, this approach can generate circular wave trains near obstacles and they propagate outwardly. We study the characteristics of such circular wave trains and further find that, the higher-frequency circular wave trains can effectively suppress spiral turbulence.
authors: Zhejiang Institute of Modern Physics and Department of Physics, Zhejiang University, Hangzhou 310027, China.
authors: Xia
authors: X
authors: Feng
authors: Zhejiang Institute of Modern Physics and Department of Physics, Zhejiang University, Hangzhou 310027, China.|School of Physics and Information Technology, Shaanxi Normal University, Xi'an 710062, China.
authors: Xiang
authors: X
authors: Gao
authors: Zhejiang Institute of Modern Physics and Department of Physics, Zhejiang University, Hangzhou 310027, China.
authors: Juan-Mei
authors: JM
authors: Tang
authors: Institute of Physical Oceanography and Ocean College, Zhejiang University, Hangzhou 310058, China.
authors: Jun-Ting
authors: JT
authors: Pan
authors: Zhejiang Institute of Modern Physics and Department of Physics, Zhejiang University, Hangzhou 310027, China.
authors: Hong
authors: H
authors: Zhang
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D003198:Computer Simulation; D004574:Electromagnetic Fields; D006329:Heart Conduction System / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D009435:Synaptic Transmission / Q000502:physiology*