title: Clinical Research Office of the Endourological Society Global GreenLight Laser Study: Outcomes from a contemporary series of 713 patients.
abstract: OBJECTIVE
  To evaluate the outcome in patients undergoing photoselective vaporization of the prostate for benign prostatic obstruction as part of the Clinical Research Office of the Endourological Society Global GreenLight Laser Study.
  
  
  METHODS
  Data were collected on 713 patients with lower urinary tract symptoms suggestive of benign prostatic obstruction undergoing photoselective vaporization of the prostate at 25 centers worldwide, between April 2010 and April 2012. Three types of GreenLight laser powers were used: 80 W, 120 W or 180 W. Intraoperative and postoperative complications were recorded. Outcome parameters measured at baseline, 6-12 weeks, 6 months and 12 months were: uroflow measurements, International Prostate Symptom Score; prostate-specific antigen and International Index of Erectile Function.
  
  
  RESULTS
  Operating time was shortest with the 180-W laser at 53.8 min. Intraoperatively, bleeding occurred in 3.1% of patients. Statistically significant changes were reported in maximum flow rate, postvoid residual urine, International Prostate Symptom Score, quality of life score and prostate-specific antigen (P < 0.01) at each time-point assessed for the 80- and 120-W lasers as well as for the 180-W laser, with the exception of prostate-specific antigen at 6 months and 12 months. There were 14 Clavien-Dindo grade III-A complications and two grade III-B. The incontinence rate at 12 months was 6.3%, 4.5%, and 2.6% for the 80, 120 and 180 W lasers, respectively. The overall blood transfusion rate was 0.4%.
  
  
  CONCLUSIONS
  Objective and subjective improvement after GreenLight laser treatment worldwide was significant at 1-year follow up. Morbidity and complications were low. Although not a randomized control study, the data can provide an indication of the outcome of the different GreenLight laser powers.
authors: Department of Urology, AMC University Hospital, Amsterdam, The Netherlands.
authors: Jean
authors: J
authors: de la Rosette
authors: Division of Urology, Department of Surgery, McGill University Health Centre, Montreal, Quebec, Canada.
authors: Mostafa
authors: M
authors: Elhilali
authors: Department of Urology, Harasanshin Hospital, Kyushu University, Fukuoka, Japan.
authors: Seiji
authors: S
authors: Naito
authors: Department of Urology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors: Dogan
authors: D
authors: Unal
authors: Division of Urology, Department of Surgery, Western University, London, Ontario, Canada.
authors: Hassan
authors: H
authors: Razvi
authors: Department of Urology, University of Patras, Rio Patras, Greece.
authors: Evangelos
authors: E
authors: Liatsikos
authors: Department of Urology, University Hospital, Basel, Switzerland.
authors: Alexander
authors: A
authors: Bachmann
authors: Department of Urology, Sant'Andrea Hospital, Rome, Italy.
authors: Andrea
authors: A
authors: Tubaro
authors: Department of Urology, HYGEIA Hospital, Athens, Greece.
authors: Gerasimos
authors: G
authors: Alivizatos
authors: Department of Surgery, North District Hospital, Hong Kong, China.
authors: Siu King
authors: SK
authors: Mak
authors: Department of Urology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
authors: Gopal
authors: G
authors: Badlani
authors: Department of Urology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors: Ehab
authors: E
authors: Eltahawy
authors: Division of Urology, University Hospitals Ahuja Medical Center, Beachwood, Ohio, USA.|Center for Minimally Invasive and Robotic Surgery, University Hospitals Parma Medical Center, Parma, Ohio, USA.|Minimally Invasive and Robotic Surgery, SouthWest Urology, LLC, Cleveland, Ohio, USA.
authors: Carson
authors: C
authors: Wong
authors: Hospital Angeles Del Pedregal, Mexico City, Mexico.
authors: Martin
authors: M
authors: Telich Vidal
authors: Department of Urology, Weill Medical College of Cornell University, New York, New York, USA.
authors: Alexis
authors: A
authors: Te
authors: Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
authors: Frank
authors: F
authors: d'Ancona
authors: Department of Urology, St. Olavs University Hospital, Trondheim, Norway.
authors: Carl-Jørgen
authors: CJ
authors: Arum
authors: Department of Urology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
authors: Jorge
authors: J
authors: Gutierrez
mesh_terms: D000368:Aged; D016063:Blood Loss, Surgical; D001803:Blood Transfusion; D003116:Color; D007172:Erectile Dysfunction / Q000209:etiology; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods*; D059411:Lower Urinary Tract Symptoms / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods; D011470:Prostatic Hyperplasia / Q000150:complications / Q000601:surgery*; D011788:Quality of Life; D012720:Severity of Illness Index; D063189:Symptom Assessment; D014549:Urinary Incontinence / Q000209:etiology; D014563:Urodynamics
chemical_list: D017430:Prostate-Specific Antigen
keywords: GreenLight laser; benign prostatic obstruction; outcome; patient characteristics; photo selective vaporization of the prostate