title: Nocardia thailandica Pulmonary Nocardiosis in a Post-Solid Organ Transplant Patient.
abstract: Nocardia thailandica is a rare pathogen related to Nocardia asteroides, Nocardia neocaledoniensis, and Nocardia caishijiensis that, since its original description in 2004, has only been reported to cause wound and ocular infections in humans. We report a case of pulmonary nocardiosis caused by Nocardia thailandica in a 66-year-old solid organ transplant patient from Connecticut, which was identified at the molecular taxonomic level by secA1 analysis, 16S rRNA gene sequencing, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). To our knowledge, this is the first reported case of N. thailandica in the United States and the first report of pulmonary infection by this pathogen in the literature.
authors: Division of Infectious Diseases, Yale School of Medicine/Yale-New Haven Hospital, New Haven, Connecticut, USA.
authors: Joseph
authors: J
authors: Canterino
authors: Microbiology Laboratory, Department of Laboratory Medicine, Yale School of Medicine/Yale-New Haven Hospital, New Haven, Connecticut, USA albertopaniz@yahoo.com.
authors: Alberto
authors: A
authors: Paniz-Mondolfi
authors: Department of Microbiology, The University of Texas Health Science Center, Mycobacteria/Nocardia Laboratory, Tyler, Texas, USA.
authors: Barbara A
authors: BA
authors: Brown-Elliott
authors: Laboratory of Microbiology, VA Connecticut Healthcare, West Haven, Connecticut, USA.
authors: Wilson
authors: W
authors: Vientos
authors: Department of Microbiology, The University of Texas Health Science Center, Mycobacteria/Nocardia Laboratory, Tyler, Texas, USA.
authors: Ravikiran
authors: R
authors: Vasireddy
authors: Department of Microbiology, The University of Texas Health Science Center, Mycobacteria/Nocardia Laboratory, Tyler, Texas, USA.
authors: Richard J
authors: RJ
authors: Wallace
authors: Microbiology Laboratory, Department of Laboratory Medicine, Yale School of Medicine/Yale-New Haven Hospital, New Haven, Connecticut, USA Laboratory of Microbiology, VA Connecticut Healthcare, West Haven, Connecticut, USA.
authors: Sheldon
authors: S
authors: Campbell
mesh_terms: D000251:Adenosine Triphosphatases / Q000235:genetics; D000368:Aged; D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D003237:Connecticut; D004269:DNA, Bacterial / Q000235:genetics; D004275:DNA, Ribosomal / Q000235:genetics; D016027:Heart Transplantation / Q000009:adverse effects; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008171:Lung Diseases / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D008297:Male; D026901:Membrane Transport Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D009615:Nocardia / Q000302:isolation & purification*; D009617:Nocardia Infections / Q000175:diagnosis* / Q000276:immunology* / Q000382:microbiology; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D000069816:SEC Translocation Channels; D000081416:SecA Proteins; D017422:Sequence Analysis, DNA; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D026901:Membrane Transport Proteins; D012336:RNA, Ribosomal, 16S; D000069816:SEC Translocation Channels; D000251:Adenosine Triphosphatases; D000081416:SecA Proteins