title: 1.0 T open-configuration magnetic resonance-guided microwave ablation of pig livers in real time.
abstract: The current fastest frame rate of each single image slice in MR-guided ablation is 1.3 seconds, which means delayed imaging for human at an average reaction time: 0.33 seconds. The delayed imaging greatly limits the accuracy of puncture and ablation, and results in puncture injury or incomplete ablation. To overcome delayed imaging and obtain real-time imaging, the study was performed using a 1.0-T whole-body open configuration MR scanner in the livers of 10 Wuzhishan pigs. A respiratory-triggered liver matrix array was explored to guide and monitor microwave ablation in real-time. We successfully performed the entire ablation procedure under MR real-time guidance at 0.202 s, the fastest frame rate for each single image slice. The puncture time ranged from 23 min to 3 min. For the pigs, the mean puncture time was shorted to 4.75 minutes and the mean ablation time was 11.25 minutes at power 70 W. The mean length and widths were 4.62 ± 0.24 cm and 2.64 ± 0.13 cm, respectively. No complications or ablation related deaths during or after ablation were observed. In the current study, MR is able to guide microwave ablation like ultrasound in real-time guidance showing great potential for the treatment of liver tumors.
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Jun
authors: J
authors: Dong
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Liang
authors: L
authors: Zhang
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Wang
authors: W
authors: Li
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Siyue
authors: S
authors: Mao
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Yiqi
authors: Y
authors: Wang
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Deling
authors: D
authors: Wang
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Lujun
authors: L
authors: Shen
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Annan
authors: A
authors: Dong
authors: Department of Medical Imaging &Image Guided Therapy, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; East Dong Feng Road 651, Guangzhou, Guangdong 510060, P. R. China.
authors: Peihong
authors: P
authors: Wu
mesh_terms: D055011:Ablation Techniques; D000818:Animals; D003199:Computer Systems; D021621:Imaging, Three-Dimensional; D008099:Liver / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008872:Microwaves; D034421:Sus scrofa