title: Carboxylated graphene oxide/polyvinyl chloride as solid-phase extraction sorbent combined with ion chromatography for the determination of sulfonamides in cosmetics.
abstract: A carboxylated graphene oxide/polyvinyl chloride (CGO/PVC) material was prepared as a sorbent for the selective extraction of sulphonamides from complex sample. After being dispersed in buffer solution, sample was transferred into the prefabricated solid-phase extraction (SPE) column, which integrated extraction and cleanup into one single-step. A multi-response optimization based on the Box-Behnken design was used to optimize factors affecting extraction efficiency. Compared with the commonly commercial sorbents including MCX, WCX and C18, CGO/PVC hybrid material had higher extraction selectivity and capacity to sulphonamides. The limits of detection and quantification for seven target compounds were in the range of 3.4-7.1 μg/L and 11.4-23.7 μg/L, respectively. The self-assembly SPE cartridge was successfully used to enrich seven analytes in anti-acne cosmetics prior to ion chromatography detection with good recoveries of 87.8-102.0% and relative standard deviations of 1.2-6.4%, implying that this method was suitable for routine analysis of cosmetics.
authors: Center for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China. Electronic address: zzxiong608@126.com.
authors: Zhixiong
authors: Z
authors: Zhong
authors: School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275, China.
authors: Gongke
authors: G
authors: Li
authors: Center for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China.
authors: Zhibin
authors: Z
authors: Luo
authors: Center for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China.
authors: Zhe
authors: Z
authors: Liu
authors: Center for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China.
authors: Yijuan
authors: Y
authors: Shao
authors: Center for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China.
authors: Wanwen
authors: W
authors: He
authors: Department of Food Engineering and Quality Safety, South China Sea Fisheries Research Institute, China.
authors: Jianchao
authors: J
authors: Deng
authors: Center for Disease Control and Prevention of Guangdong Province, Guangzhou 510300, China.
authors: Xingling
authors: X
authors: Luo
mesh_terms: D002852:Chromatography, Ion Exchange / Q000379:methods; D003358:Cosmetics / Q000032:analysis*; D006108:Graphite / Q000737:chemistry*; D057230:Limit of Detection; D010087:Oxides / Q000737:chemistry*; D011143:Polyvinyl Chloride / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000379:methods*; D013449:Sulfonamides / Q000302:isolation & purification*
chemical_list: D003358:Cosmetics; D010087:Oxides; D013449:Sulfonamides; D006108:Graphite; D011143:Polyvinyl Chloride
keywords: Anti-acne cosmetics; Carboxylated graphene oxide/polyvinyl chloride; Ion chromatography; Multi-response optimization; Solid-phase extraction; Sulphonamides