title: Detecting the unexpected.
abstract: Sensory input is inherently dynamic and redundant. Humans and animals alike show a remarkable ability to extract regularities from the sensory scene and dynamically update their responses to the environment. This type of short-term plasticity occurs on time scales ranging from seconds to minutes (and possibly longer). Mismatch Negativity (a component of the human event-related potentials, MMN) and Stimulus Specific Adaptation (a single-neuron analogue, SSA) are two examples of this form of short-term plasticity. Conceptually, both are thought to express a form of surprise and to represent predictive processing. MMN and SSA therefore provide us with handles for investigating this important time scale of short-term plasticity.
authors: Edmond and Lily Safra Center for Brain Sciences and the Department of Neuroscience, The Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Edmond J. Safra Campus, 9190401 Jerusalem, Israel.
authors: Leila
authors: L
authors: Khouri
authors: Edmond and Lily Safra Center for Brain Sciences and the Department of Neuroscience, The Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Edmond J. Safra Campus, 9190401 Jerusalem, Israel. Electronic address: israel@cc.huji.ac.il.
authors: Israel
authors: I
authors: Nelken
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D005071:Evoked Potentials / Q000502:physiology*; D006801:Humans; D009473:Neuronal Plasticity / Q000502:physiology*