title: Distribution of immunoglobulin G antibody secretory cells in small intestine of Bactrian camels (Camelus bactrianus).
abstract: BACKGROUND
  To explore the morphological evidence of immunoglobulin G (IgG) participating in intestinal mucosal immunity, 8 healthy adult Bactrian camels used. First, IgG was successfully isolated from their serum and rabbit antibody against Bactrian camels IgG was prepared. The IgG antibody secretory cells (ASCs) in small intestine were particularly observed through immumohistochemical staining, then after were analyzed by statistical methods.
  
  
  RESULTS
  The results showed that the IgG ASCs were scattered in the lamina propria (LP) and some of them aggregated around of the intestinal glands. The IgG ASCs density was the highest from middle segment of duodenum to middle segment of jejunum, and then in ended segment of jejunum and initial segment of ileum, the lowest was in initial segment of duodenum, in middle and ended segment of ileum.
  
  
  CONCLUSIONS
  It was demonstrated that the IgG ASCs mainly scattered in the effector sites of the mucosal immunity, though the density of IgG ASCs was different in different segment of small intestine. Moreover, this scatted distribution characteristic would provide a morphology basis for research whether IgG form a full-protection and immune surveillance in mucosal immunity homeostasis of integral intestine.
authors: College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, Gansu, China. awang001@126.com.
authors: Wang-Dong
authors: WD
authors: Zhang
authors: College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, Gansu, China. wwh777@126.com.
authors: Wen-Hui
authors: WH
authors: Wang
authors: College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, Gansu, China. jiashuaialaddin@163.com.
authors: Shuai
authors: S
authors: Jia
mesh_terms: D000818:Animals; D002162:Camelus; D018928:Immunity, Mucosal; D007074:Immunoglobulin G / Q000378:metabolism*; D007421:Intestine, Small / Q000166:cytology*
chemical_list: D007074:Immunoglobulin G