title: M-Protein Analysis of Streptococcus pyogenes Isolates Associated with Acute Rheumatic Fever in New Zealand.
abstract: We applied an emm cluster typing system to group A Streptococcus strains in New Zealand, including those associated with acute rheumatic fever (ARF). We observed few so-called rheumatogenic emm types but found a high proportion of emm types previously associated with pyoderma, further suggesting a role for skin infection in ARF.
authors: Institute of Environmental Science and Research, Wellington, New Zealand Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand University of Otago, Wellington, New Zealand debbie.williamson@otago.ac.nz.
authors: Deborah A
authors: DA
authors: Williamson
authors: Murdoch Childrens Research Institute, Melbourne, Australia Center for International Child Health, University of Melbourne, Australia.
authors: Pierre R
authors: PR
authors: Smeesters
authors: Murdoch Childrens Research Institute, Melbourne, Australia Center for International Child Health, University of Melbourne, Australia.
authors: Andrew C
authors: AC
authors: Steer
authors: School of Biological Sciences, University of Auckland, Auckland, New Zealand.
authors: John D
authors: JD
authors: Steemson
authors: School of Biological Sciences, University of Auckland, Auckland, New Zealand.
authors: Adrian C H
authors: AC
authors: Ng
authors: Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand School of Medical Sciences, University of Auckland, Auckland, New Zealand.
authors: Thomas
authors: T
authors: Proft
authors: Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand School of Medical Sciences, University of Auckland, Auckland, New Zealand.
authors: John D
authors: JD
authors: Fraser
authors: University of Otago, Wellington, New Zealand.
authors: Michael G
authors: MG
authors: Baker
authors: Institute of Environmental Science and Research, Wellington, New Zealand.
authors: Julie
authors: J
authors: Morgan
authors: Institute of Environmental Science and Research, Wellington, New Zealand.
authors: Philip E
authors: PE
authors: Carter
authors: Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand School of Biological Sciences, University of Auckland, Auckland, New Zealand.
authors: Nicole J
authors: NJ
authors: Moreland
mesh_terms: D000942:Antigens, Bacterial / Q000235:genetics*; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D002352:Carrier Proteins / Q000235:genetics*; D006801:Humans; D017720:Molecular Epidemiology / Q000379:methods; D058889:Molecular Typing; D009520:New Zealand / Q000453:epidemiology; D012189:Retrospective Studies; D012213:Rheumatic Fever / Q000453:epidemiology* / Q000382:microbiology; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity
chemical_list: D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D002352:Carrier Proteins; C014689:streptococcal M protein