title: A quantitative model to predict blood use in adult orthotopic liver transplantation.
abstract: To identify preoperative predictors for the use of any blood component during and after orthotopic liver transplantation (OLT), we performed a retrospective analysis on 602 OLT patients who were randomly split into a training set (n = 482) and a validation set (n = 120). Hemoglobin and calculated MELD score were identified as independent predictors for blood use using bootstrap aggregation. A logistic regression model constructed using both variables showed comparable performance in the training and validation sets. Predictive scores can be obtained from a nomogram, and a score above -2.328 predicted transfusion of any blood component with a positive predictive value of 97% and 96% in the training and validation sets, respectively.
authors: Department of Pathology & Immunology, Washington University, St. Louis, MO, USA.
authors: Chang
authors: C
authors: Liu
authors: Department of Surgery, Washington University, St. Louis, MO, USA.
authors: Neeta
authors: N
authors: Vachharajani
authors: Department of Internal Medicine, St. Luke's Hospital, St. Louis, MO, USA.
authors: Shuang
authors: S
authors: Song
authors: Department of Pathology, University of Maryland, Baltimore, MD, USA.
authors: Rhonda
authors: R
authors: Cooke
authors: Department of Anesthesiology, Washington University, St. Louis, MO, USA.
authors: Ivan
authors: I
authors: Kangrga
authors: Department of Surgery, Washington University, St. Louis, MO, USA.
authors: William C
authors: WC
authors: Chapman
authors: Department of Pathology & Immunology, Washington University, St. Louis, MO, USA. Electronic address: bgrossman@pathology.wustl.edu.
authors: Brenda J
authors: BJ
authors: Grossman
mesh_terms: D001803:Blood Transfusion; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D011237:Predictive Value of Tests
keywords: Blood transfusion; Hemoglobin; International normalized ratio (INR); Model for End-Stage Liver Disease (MELD) score; Orthotopic liver transplantation