title: Characteristics of canine platelet-rich plasma prepared with five commercially available systems.
abstract: OBJECTIVE
  To characterize platelet-rich plasma (PRP) products obtained from canine blood by use of a variety of commercially available devices.
  
  
  METHODS
  Blood samples from 15 dogs between 18 months and 9 years of age with no concurrent disease, except for osteoarthritis in some dogs.
  
  
  METHODS
  PRP products were produced from blood obtained from each of the 15 dogs by use of each of 5 commercially available PRP-concentrating systems. Complete blood counts were performed on each whole blood sample and PRP product. The degree of platelet, leukocyte, and erythrocyte concentration or reduction for PRP, compared with results for the whole blood sample, was quantified for each dog and summarized for each concentrating system.
  
  
  RESULTS
  The various PRP-concentrating systems differed substantially in the amount of blood processed, method of PRP preparation, amount of PRP produced, and platelet, leukocyte, and erythrocyte concentrations or reductions for PRP relative to results for whole blood.
  
  
  CONCLUSIONS
  The characteristics of PRP products differed considerably. Investigators evaluating the efficacy of PRPs need to specify the characteristics of the product they are assessing. Clinicians should be aware of the data (or lack of data) supporting use of a particular PRP for a specific medical condition.
authors: Samuel P
authors: SP
authors: Franklin
authors: Bridget C
authors: BC
authors: Garner
authors: James L
authors: JL
authors: Cook
mesh_terms: D000818:Animals; D020811:Biomedical Technology / Q000295:instrumentation*; D001792:Blood Platelets / Q000502:physiology*; D004285:Dogs / Q000097:blood*; D004912:Erythrocytes; D007962:Leukocytes; D010956:Plasmapheresis / Q000295:instrumentation / Q000379:methods / Q000662:veterinary*; D053657:Platelet-Rich Plasma / Q000737:chemistry* / Q000166:cytology*