title: Rhodium-Catalyzed Asymmetric 1,4-Addition of α,β-Unsaturated Imino Esters Using Chiral Bicyclic Bridgehead Phosphoramidite Ligands.
abstract: A chiral bicyclic bridgehead phosphoramidite (briphos) prepared from 1-aminoindane is a highly efficient and selective ligand for rhodium(I)-catalyzed asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated N,N-dimethyl-sulfamoyl imino esters at ambient temperature. This transformation provides a new class of chiral (Z)-γ,γ-diaryl-α,β-dehydroamino esters with excellent yield and enantioselectivity.
authors: Department of Chemistry, KAIST , Daejeon 34141, Korea.
authors: Ansoo
authors: A
authors: Lee
authors: Department of Chemistry, KAIST , Daejeon 34141, Korea.|Center for Nanomaterials and Chemical Reactions, Institute for Basic Science , Daejeon 34141, Korea.
authors: Hyunwoo
authors: H
authors: Kim