title: Association between Ocular Sensory Dominance and Refractive Error Asymmetry.
abstract: OBJECTIVE
  To investigate the association between ocular sensory dominance and interocular refractive error difference (IRED).
  
  
  METHODS
  A total of 219 subjects were recruited. The refractive errors were determined by objective refraction with a fixation target located 6 meters away. 176 subjects were myopic, with 83 being anisometropic (IRED ≥ 0.75 D). 43 subjects were hyperopic, with 22 being anisometropic. Sensory dominance was measured with a continuous flashing technique with the tested eye viewing a Gabor increasing in contrast and the fellow eye viewing a Mondrian noise decreasing in contrast. The log ratio of Mondrian to Gabor's contrasts was recorded when a subject just detected the tilting direction of the Gabor during each trial. T-test was used to compare the 50 values collected from each eye, and the t-value was used as a subject's ocular dominance index (ODI) to quantify the degree of ocular dominance. A subject with ODI ≥ 2 (p < 0.05) had clear dominance and the eye with larger mean ratio was the dominant one. Otherwise, a subject had an unclear dominance.
  
  
  RESULTS
  The anisometropic subjects had stronger ocular dominance in comparison to non-anisometropic subjects (rank-sum test, p < 0.01 for both myopic and hyperopic subjects). In anisometropic subjects with clear dominance, the amplitude of the anisometropia was correlated with ODI values (R = 0.42, p < 0.01 in myopic anisometropic subjects; R = 0.62, p < 0.01 in hyperopic anisometropic subjects). Moreover, the dominant eyes were more myopic in myopic anisometropic subjects (sign-test, p < 0.05) and less hyperopic in hyperopic anisometropic subjects (sign-test, p < 0.05).
  
  
  CONCLUSIONS
  The degree of ocular sensory dominance is associated with interocular refractive error difference.
authors: Medical School of Chinese PLA, Beijing, China; Department of Ophthalmology, Jinling Hospital, Nanjing, China.
authors: Feng
authors: F
authors: Jiang
authors: Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors: Zheyi
authors: Z
authors: Chen
authors: College of Optometry, Nova Southeastern University, Davie, Florida, United States of America.
authors: Hua
authors: H
authors: Bi
authors: College of Optometry, Nova Southeastern University, Davie, Florida, United States of America.
authors: Edgar
authors: E
authors: Ekure
authors: Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors: Binbin
authors: B
authors: Su
authors: Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors: Haoran
authors: H
authors: Wu
authors: Medical School of Chinese PLA, Beijing, China.
authors: Yifei
authors: Y
authors: Huang
authors: Eye Hospital of Wenzhou Medical University, Wenzhou, China; College of Optometry, Nova Southeastern University, Davie, Florida, United States of America.
authors: Bin
authors: B
authors: Zhang
authors: Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors: Jun
authors: J
authors: Jiang
mesh_terms: D000293:Adolescent; D000328:Adult; D015858:Anisometropia / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D023882:Dominance, Ocular / Q000502:physiology*; D005123:Eye; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D012029:Refraction, Ocular; D014792:Visual Acuity / Q000502:physiology