title: Actin shapes the autophagosome.
abstract: Compared with most intracellular vesicles, the autophagosome is formed by an unusual event of vesicle budding involving an elusive sequence of membrane expansions that ends with a double membrane vesicle. It is now shown that actin polymerization inside the forming autophagosome is a driving force for the expansion and assembly of a functional autophagosome.
authors: Department of Molecular Medicine, Insititute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway.
authors: Petter
authors: P
authors: Holland
authors: Department of Molecular Medicine, Insititute of Basic Medical Sciences, University of Oslo, 0317 Oslo, Norway.
authors: Anne
authors: A
authors: Simonsen
mesh_terms: D008841:Actin Cytoskeleton / Q000378:metabolism*; D000818:Animals; D001343:Autophagy; D051347:CapZ Actin Capping Protein / Q000502:physiology*; D007425:Intracellular Membranes / Q000378:metabolism*; D010588:Phagosomes / Q000378:metabolism*
chemical_list: D051347:CapZ Actin Capping Protein