title: Imidazopyridines as a source of biological activity and their pharmacological potentials-Infrared and Raman spectroscopic evidence of their content in pharmaceuticals and plant materials.
abstract: Derivatives of imidazopyridine are used in medicinal chemistry due to their biological and pharmaceutical properties. This review article presents imidazopyridine pharmacological activity as antiinflammatory, anticancer, antiviral, antiosteoporotic, antiparasitic, and antihypertensive agents by studying its various synthesized derivatives. Some of compounds with imidazopyridine skeleton are used in psychiatry and autoimmune disorders. The presented data suggest that IR and Raman spectra measurements are a good methods for identification and characterization of the compounds containing imidazopyridine core. Two stretching vibrations: νas(Φ) and νs(Φ) are of a diagnostic importance. The appearance of these bands in the IR and Raman spectra of some plants, tissues and pharmaceuticals confirms the presence of imidazopyridine skeleton in these substances.
authors: Department of Bioorganic Chemistry, Institute of Chemistry and Food Technology, Faculty of Engineering and Economics, Wrocław University of Economics, 118/120 Komandorska, 53-345 Wrocław, Poland. Electronic address: lucyna.dyminska@ue.wroc.pl.
authors: Lucyna
authors: L
authors: Dymińska
mesh_terms: D000893:Anti-Inflammatory Agents / Q000737:chemistry; D000959:Antihypertensive Agents / Q000737:chemistry; D000970:Antineoplastic Agents / Q000737:chemistry; D000977:Antiparasitic Agents / Q000737:chemistry; D014150:Antipsychotic Agents / Q000737:chemistry; D000998:Antiviral Agents / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry; D008968:Molecular Conformation; D010944:Plants / Q000737:chemistry / Q000378:metabolism; D011725:Pyridines / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013059:Spectrum Analysis, Raman
chemical_list: D000893:Anti-Inflammatory Agents; D000959:Antihypertensive Agents; D000970:Antineoplastic Agents; D000977:Antiparasitic Agents; D014150:Antipsychotic Agents; D000998:Antiviral Agents; D007093:Imidazoles; D011725:Pyridines; C029899:imidazole
keywords: IR and Raman spectra; Imidazopyridine