title: Food Avoidance Diets for Dermatitis.
abstract: Food allergy is relatively common in both children and adults, and its prevalence is increasing. Early exposure of food allergens onto skin with an impaired epidermal barrier predisposes to sensitization and prevents the development of oral tolerance. While immediate-type food allergies are well described, less is known about delayed-type food allergies manifesting as dermatitis. This is due, in part, to limitations with current diagnostic testing for delayed-type food allergy, including atopy patch testing. We conducted a systematic review of food avoidance diets in delayed-type food allergies manifesting as dermatitis. While beneficial in some clinical circumstances, avoidance diets should be used with caution in infants and children, as growth impairment and developmental delay may result. Ultimately, dermatitis is highly multifactorial and avoidance diets may not improve symptoms of delayed-type food allergy until combined with other targeted therapies, including restoring balance in the skin microbiome and re-establishing proper skin barrier function.
authors: Department of Dermatology, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, USA, jeffrey.scott@uhhospitals.org.
authors: Jeffrey F
authors: JF
authors: Scott
authors: Margaret I
authors: MI
authors: Hammond
authors: Susan T
authors: ST
authors: Nedorost
mesh_terms: D000485:Allergens / Q000276:immunology; D000818:Animals; D003872:Dermatitis / Q000276:immunology*; D004032:Diet; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology; D010328:Patch Tests
chemical_list: D000485:Allergens