title: Self-images in the present and future: Role of affect and the bipolar phenotype.
abstract: BACKGROUND
  Bipolar Spectrum Disorder (BPSD) is associated with changes in self-related processing and affect, yet the relationship between self-image and affect in the BPSD phenotype is unclear.
  
  
  METHODS
  47 young adults were assessed for hypomanic experiences (BPSD phenotype) using the Mood Disorders Questionnaire. Current and future self-images (e.g. I am… I will be…) were generated and rated for emotional valence, stability, and (for future self-images only) certainty. The relationship between self-image ratings and measures of affect (depression, anxiety and mania) were analysed in relation to the BPSD phenotype.
  
  
  RESULTS
  The presence of the BPSD phenotype significantly moderated the relationship between (1) affect and stability ratings for negative self-images, and (2) affect and certainty ratings for positive future self-images. Higher positivity ratings for current self-images were associated with lower depression and anxiety scores.
  
  
  CONCLUSIONS
  This was a non-clinical group of young adults sampled for hypomanic experiences, which limits the extension of the work to clinical levels of psychopathology. This study cannot address the causal relationships between affect, self-images, and BPSD. Future work should use clinical samples and experimental mood manipulation designs.
  
  
  CONCLUSIONS
  BPSD phenotype can shape the relationship between affect and current and future self-images. This finding will guide future clinical research to elucidate BPSD vulnerability mechanisms and, consequently, the development of early interventions.
authors: MRC Cognition and Brain Sciences Unit, Cambridge,UK. Electronic address: martina.disimplicio@mrc-cbu.cam.ac.uk.
authors: Martina
authors: M
authors: Di Simplicio
authors: MRC Cognition and Brain Sciences Unit, Cambridge,UK; Department of Clinical Neuroscience, Karonlinska Institutet, Stockholm, Sweden.
authors: Emily A
authors: EA
authors: Holmes
authors: Department of Psychology, Social Work and Public Health, Oxford Brookes University, Oxford, UK.
authors: Clare J
authors: CJ
authors: Rathbone
mesh_terms: D000328:Adult; D000339:Affect; D001007:Anxiety / Q000150:complications / Q000523:psychology*; D001714:Bipolar Disorder / Q000150:complications / Q000523:psychology*; D003863:Depression / Q000150:complications / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D010641:Phenotype; D012649:Self Concept; D012919:Social Behavior; D057545:Social Stigma; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Anxiety; Bipolar disorder; Hypomania; Identity; Mood; Prospection; Self-image