title: Dicing up T-ALL.
abstract: In this issue of Blood, Junker et al delineate a novel signaling axis involving miR-21 and the tumor suppressor Pdcd4 that is essential for Notch-mediated induction of T-cell acute lymphoblastic leukemia (T-ALL).
authors: BRIGHAM AND WOMEN'S HOSPITAL.
authors: Jon C
authors: JC
authors: Aster
mesh_terms: D000818:Animals; D051017:Apoptosis Regulatory Proteins / Q000378:metabolism*; D015972:Gene Expression Regulation, Neoplastic / Q000502:physiology*; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D016601:RNA-Binding Proteins / Q000378:metabolism*; D043244:Ribonuclease III / Q000378:metabolism*
chemical_list: D051017:Apoptosis Regulatory Proteins; D035683:MicroRNAs; D016601:RNA-Binding Proteins; D043244:Ribonuclease III