title: Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents.
abstract: Black phosphorus quantum dots (BPQDs) were synthesized using a liquid exfoliation method that combined probe sonication and bath sonication. With a lateral size of approximately 2.6 nm and a thickness of about 1.5 nm, the ultrasmall BPQDs exhibited an excellent NIR photothermal performance with a large extinction coefficient of 14.8 L g(-1) cm(-1) at 808 nm, a photothermal conversion efficiency of 28.4%, as well as good photostability. After PEG conjugation, the BPQDs showed enhanced stability in physiological medium, and there was no observable toxicity to different types of cells. NIR photoexcitation of the BPQDs in the presence of C6 and MCF7 cancer cells led to significant cell death, suggesting that the nanoparticles have large potential as photothermal agents.
authors: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055 (P. R. China).|SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060 (P. R. China).
authors: Zhengbo
authors: Z
authors: Sun
authors: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055 (P. R. China).
authors: Hanhan
authors: H
authors: Xie
authors: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055 (P. R. China).
authors: Siying
authors: S
authors: Tang
authors: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055 (P. R. China). xf.yu@siat.ac.cn.
authors: Xue-Feng
authors: XF
authors: Yu
authors: SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060 (P. R. China).
authors: Zhinan
authors: Z
authors: Guo
authors: SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060 (P. R. China).
authors: Jundong
authors: J
authors: Shao
authors: SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060 (P. R. China). hzhang@szu.edu.cn.
authors: Han
authors: H
authors: Zhang
authors: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055 (P. R. China).|Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong (P. R. China).
authors: Hao
authors: H
authors: Huang
authors: Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055 (P. R. China).
authors: Huaiyu
authors: H
authors: Wang
authors: Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong (P. R. China). paul.chu@cityu.edu.hk.
authors: Paul K
authors: PK
authors: Chu
mesh_terms: D045744:Cell Line, Tumor; D006801:Humans; D018625:Microscopy, Atomic Force; D046529:Microscopy, Electron, Transmission; D010758:Phosphorus / Q000737:chemistry*; D045663:Quantum Dots; D019265:Spectroscopy, Near-Infrared
chemical_list: D010758:Phosphorus
keywords: black phosphorus; nanocrystals; photothermal agents; photothermal therapy; quantum dots