title: Palladium-catalyzed direct and regioselective C-H acyloxylation of indolizines.
abstract: A direct and regioselective C1-acyloxylation of indolizines was developed via palladium-catalyzed C-H functionalization. A series of indolizines were successfully acyloxylated at the C1 position with the tolerance of a broad range of functional groups. In this reaction, high regioselectivity was achieved in the absence of a directing group. This work represents the first example of indolizine acyloxylation via C-H activation.
authors: Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials and Institute of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou 221116, Jiangsu, P. R. China. wuhui72@126.com xznuliuyun@jsnu.edu.cn.
authors: Jinwei
authors: J
authors: Sun
authors: Fuyao
authors: F
authors: Wang
authors: Yongmiao
authors: Y
authors: Shen
authors: Huizhen
authors: H
authors: Zhi
authors: Hui
authors: H
authors: Wu
authors: Yun
authors: Y
authors: Liu
mesh_terms: D002384:Catalysis; D007212:Indolizines / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007212:Indolizines; D009942:Organometallic Compounds; D010165:Palladium