title: [Radiotherapy of bone metastases: Which fractionations?].
abstract: First-line palliative radiotherapy for painful bone metastases is an effective treatment whatever its fractionation (single or multiple fractions). It is also indicated after failure or insufficient effect of a first irradiation, or the appearance of new painful site. Other indications are spinal cord compression, either as an adjuvant to surgery or as sole treatment, and after surgery for long bone metastases. The development of high precision techniques (stereotactic conditions) widens the possibility of re-irradiation when tolerance doses to normal tissues have already been delivered. Local control and possibly overall survival could be improved in oligometastatic patients.
authors: Quantif-Litis EA 4108, département de radiothérapie et de physique médicale, département de médecine nucléaire, centre Henri-Becquerel, 76038 Rouen, France. Electronic address: sebastien.thureau@chb.unicancer.fr.
authors: S
authors: S
authors: Thureau
authors: Département de radiothérapie, centre Antoine-Lacassagne, 33, avenue Valombrose, 06100 Nice, France.
authors: A
authors: A
authors: Leysalle
authors: Département de radiothérapie, institut de cancérologie de Lorraine-Alexis-Vautrin, 6, avenue de Bourgogne, 54511 Vandœuvre-lès-Nancy, France.
authors: J-C
authors: JC
authors: Faivre
authors: Service de radiothérapie, hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France; Upec, avenue du Général-de-Gaulle, 94010 Créteil cedex, France.
authors: J-L
authors: JL
authors: Lagrange
mesh_terms: D001859:Bone Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D019583:Dose Fractionation, Radiation; D006801:Humans
keywords: Bone metastasis; Dose fractionation; Douleur; Fractionnement; Métastases osseuses; Pain; Radiosurgery; Radiotherapy; Radiothérapie; Stéréotaxie