title: Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease.
authors: K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors: Marita
authors: M
authors: Westhrin
authors: K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors: Siv Helen
authors: SH
authors: Moen
authors: K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors: Toril
authors: T
authors: Holien
authors: Department of Haematology, Rigshospitalet, University of Copenhagen, Denmark.
authors: Anne Kærsgaard
authors: AK
authors: Mylin
authors: Department of Clinical Biochemistry, Aarhus University Hospital, Denmark.
authors: Lene
authors: L
authors: Heickendorff
authors: K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors: Oddrun Elise
authors: OE
authors: Olsen
authors: K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors: Anders
authors: A
authors: Sundan
authors: Department of Hematology, Skane University Hospital, Malmo, Sweden.
authors: Ingemar
authors: I
authors: Turesson
authors: Department of Haematology, Rigshospitalet, University of Copenhagen, Denmark.
authors: Peter
authors: P
authors: Gimsing
authors: K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors: Anders
authors: A
authors: Waage
authors: K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway therese.standal@ntnu.no.
authors: Therese
authors: T
authors: Standal
mesh_terms: D001859:Bone Neoplasms / Q000097:blood* / Q000473:pathology; D002454:Cell Differentiation; D005260:Female; D055436:Growth Differentiation Factor 15 / Q000097:blood*; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000097:blood* / Q000473:pathology; D009363:Neoplasm Proteins / Q000097:blood*; D010006:Osteoblasts / Q000378:metabolism* / Q000473:pathology; D010010:Osteoclasts / Q000378:metabolism* / Q000473:pathology
chemical_list: C526140:GDF15 protein, human; D055436:Growth Differentiation Factor 15; D009363:Neoplasm Proteins
keywords: GDF15; multiple myeloma; osteoblast differentiation; osteoclast differentiation