title: A Dispersion-Dominated Chromogenic Strategy for Colorimetric Sensing of Glutathione at the Nanomolar Level Using Gold Nanoparticles.
abstract: A dispersion-dominated chromogenic strategy for glutathione sensing is developed. Glutathione prevents the aggregation of arginine-modified gold nanoparticles via mercury-thiol interaction, which allows for glutathione sensing at the nanomolar level (10.9 × 10(-9) m) with facile operation and naked-eye readout.
authors: Beijing Engineering Research Center for BioNanotechnology & Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors: Yunlei
authors: Y
authors: Xianyu
authors: Beijing Engineering Research Center for BioNanotechnology & Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors: Yangzhouyun
authors: Y
authors: Xie
authors: Beijing Engineering Research Center for BioNanotechnology & Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing, 100190, P. R. China.
authors: Nuoxin
authors: N
authors: Wang
authors: Beijing Engineering Research Center for BioNanotechnology & Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing, 100190, P. R. China.
authors: Zhuo
authors: Z
authors: Wang
authors: Beijing Engineering Research Center for BioNanotechnology & Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing, 100190, P. R. China.
authors: Xingyu
authors: X
authors: Jiang
mesh_terms: D002863:Chromogenic Compounds / Q000138:chemical synthesis; D003124:Colorimetry / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005978:Glutathione / Q000032:analysis* / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D008628:Mercury / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008832:Microchemistry / Q000295:instrumentation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D002863:Chromogenic Compounds; D013438:Sulfhydryl Compounds; D006046:Gold; D008628:Mercury; D005978:Glutathione
keywords: cancer cells; colorimetric sensors; glutathione; gold nanoparticles; mercury