title: Anti-TNF-α and hydralazine drug-induced lupus.
abstract: Drug-induced lupus is a rare drug reaction featuring the same symptoms as idiopathic lupus erythematosus. Recently, with the introduction of new medicines in clinical practice, an increase in the number of illness-triggering implicated drugs has been reported, with special emphasis on anti-TNF-α drugs. In the up-to-date list, almost one hundred medications have been associated with the occurrence of drug-induced lupus. The authors present two case reports of the illness induced respectively by hydralazine and infliximab, addressing the clinical and laboratorial characteristics, diagnosis, and treatment.
authors: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, BR.
authors: Maria Victória
authors: MV
authors: Quaresma
authors: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, BR.
authors: Fred
authors: F
authors: Bernardes Filho
authors: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, BR.
authors: Fernanda Brandão de
authors: FB
authors: Oliveira
authors: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, BR.
authors: Mercedes Prates
authors: MP
authors: Pockstaller
authors: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, BR.
authors: Maria Fernanda Reis Gavazzoni
authors: MF
authors: Dias
authors: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, BR.
authors: David Rubem
authors: DR
authors: Azulay
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000009:adverse effects*; D005765:Gastrointestinal Agents / Q000009:adverse effects*; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects*; D000069285:Infliximab / Q000009:adverse effects*; D008178:Lupus Erythematosus, Cutaneous / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D000959:Antihypertensive Agents; D005765:Gastrointestinal Agents; D014409:Tumor Necrosis Factor-alpha; D006830:Hydralazine; D000069285:Infliximab