title: Recommendations for the use of long-term central venous catheter (CVC) in children with hemato-oncological disorders: management of CVC-related occlusion and CVC-related thrombosis. On behalf of the coagulation defects working group and the supportive therapy working group of the Italian Association of Pediatric Hematology and Oncology (AIEOP).
abstract: Central venous catheters (CVC), used for the management of children with hemato-oncological disorders, are burdened by a significant incidence of mechanical, infective, or thrombotic complications. These complications favor an increasing risk in prolongation of hospitalization, extra costs of care, and sometimes severe life-threatening events. No guidelines for the management of CVC-related occlusion and CVC-related thrombosis are available for children. To this aim, members of the coagulation defects working group and the supportive therapy working group of the Italian Association of Pediatric Hematology and Oncology (AIEOP) reviewed the pediatric and adult literature to propose the first recommendations for the management of CVC-related occlusion and CVC-related thrombosis in children with hemato-oncological disorders.
authors: Department of Biomedicine and Human Oncology, Pediatric Unit, University of Bari "Aldo Moro", Bari, Italy.
authors: Paola
authors: P
authors: Giordano
authors: Department of Pediatrics, Hematology Unit, University of Turin, Turin, Italy. paola.saracco@unito.it.
authors: Paola
authors: P
authors: Saracco
authors: Department of Biomedicine and Human Oncology, Pediatric Unit, University of Bari "Aldo Moro", Bari, Italy.
authors: Massimo
authors: M
authors: Grassi
authors: Department of Pediatric Hematology Oncology, Bambino Gesù Children Hospital, Rome, Italy.
authors: Matteo
authors: M
authors: Luciani
authors: Thrombosis and Hemostasis Unit, Giannina Gaslini Children's Hospital, Genoa, Italy.
authors: Laura
authors: L
authors: Banov
authors: Pediatric Hematology Oncology and Bone Marrow Unit, Ospedale Infantile Regina Margherita, Turin, Italy.
authors: Francesca
authors: F
authors: Carraro
authors: Department of Surgery, General and Thoracic Surgery Unit, Bambino Gesù Children Hospital, Rome, Italy.
authors: Alessandro
authors: A
authors: Crocoli
authors: Pediatric Hematology Oncology Unit, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors: Simone
authors: S
authors: Cesaro
authors: Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy.
authors: Giulio Andrea
authors: GA
authors: Zanazzo
authors: Thrombosis and Hemostasis Unit, Giannina Gaslini Children's Hospital, Genoa, Italy.
authors: Angelo Claudio
authors: AC
authors: Molinari
mesh_terms: D000328:Adult; D001778:Blood Coagulation Disorders / Q000628:therapy*; D061807:Catheter Obstruction / Q000009:adverse effects; D002405:Catheterization, Central Venous / Q000592:standards*; D062905:Central Venous Catheters / Q000009:adverse effects / Q000592:standards / Q000706:statistics & numerical data*; D002648:Child; D019337:Hematologic Neoplasms / Q000628:therapy*; D006801:Humans; D012307:Risk Factors; D013927:Thrombosis / Q000209:etiology / Q000628:therapy*
keywords: CVC occlusion; Central venous catheter; Pediatric hematology oncology; Thrombosis