title: [Case-control study of obstetrical outcomes of conisation].
abstract: OBJECTIVE
  Evaluate the obstetrical outcomes in the case of women with a history of conization. Determine the role of the cone length in the obstetrical issue.
  
  
  METHODS
  Retrospective case-control study including the patients (n=39) who had undergone a conization in a university hospital between January 2002 and January 2012. The obstetrical outcomes have been compared to those from a control group (n=78). Into the exposed group the obstetrical outcomes has been compared based on the cone length.
  
  
  RESULTS
  Thirty-one patients delivered after a conization (39 deliveries). The obstetrical outcomes have been significantly increased in the exposed group: preterm delivery before 37 weeks gestation (25.6% vs 7.7%, P=0.01), before 32 weeks gestation (15.4% vs 1.3%, P=0.005) and between 28 weeks gestation (10.2% vs 0%, P=0.01), premature onset of labor before 32 weeks gestation (12.8% vs 1.3%, P=0.01) and before 28 weeks gestation (12.8% vs 0%, P=0.01) and preterm premature rupture of membranes before 37 weeks gestation (20.5% vs 1.3%, P<0.001). There was no significant difference for a length cone more than 1.5cm.
  
  
  CONCLUSIONS
  Our study showed that a history of conization is an obstetrical risk factor to consider in the management of a subsequent pregnancy.
authors: Département d'obstétrique, de gynécologie et de médecine de la reproduction, CHU de Caen, avenue de la Côte-de-Nacre, 14000 Caen, France. Electronic address: brieclaudia@yahoo.com.
authors: C
authors: C
authors: Brie
authors: Département d'obstétrique, de gynécologie et de médecine de la reproduction, CHU de Caen, avenue de la Côte-de-Nacre, 14000 Caen, France.
authors: M
authors: M
authors: Turck
authors: Département d'obstétrique, de gynécologie et de médecine de la reproduction, CHU de Caen, avenue de la Côte-de-Nacre, 14000 Caen, France.
authors: A
authors: A
authors: Cheret
authors: Département des statistiques médicales, CHU de Caen, avenue Clemenceau, 14033 Caen cedex 9, France.
authors: R
authors: R
authors: Morello
authors: Département d'obstétrique, de gynécologie et de médecine de la reproduction, CHU de Caen, avenue de la Côte-de-Nacre, 14000 Caen, France; Université Caen - Basse-Normandie, esplanade de la Paix, 14032 Caen cedex 5, France.
authors: G
authors: G
authors: Benoist
authors: Département d'obstétrique, de gynécologie et de médecine de la reproduction, CHU de Caen, avenue de la Côte-de-Nacre, 14000 Caen, France; Université Caen - Basse-Normandie, esplanade de la Paix, 14032 Caen cedex 5, France.
authors: M
authors: M
authors: Dreyfus
mesh_terms: D000328:Adult; D001724:Birth Weight / Q000502:physiology; D016022:Case-Control Studies; D019092:Conization / Q000009:adverse effects / Q000706:statistics & numerical data; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000453:epidemiology / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology / Q000209:etiology; D011256:Pregnancy Outcome / Q000453:epidemiology*; D047928:Premature Birth / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000534:rehabilitation / Q000601:surgery*; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology / Q000534:rehabilitation / Q000601:surgery*
keywords: Accouchement prématuré; Conisation; Conization; Grossesse; Pregnancy; Premature rupture of membranes; Preterm birth; Rupture prématurée des membranes