title: The effect of extensive intraoperative peritoneal lavage therapy (EIPL) on stage III B + C and cytology-positive gastric cancer patients.
abstract: BACKGROUND
  The aim of this study was to investigate the effects of extensive intraoperative peritoneal lavage (EIPL) therapy on stage III B + C and CY1/P0 gastric cancer patients after potentially curative surgery.
  
  
  METHODS
  The study included 37 patients with CY1/P0 and 23 patients with stage III B + C gastric cancer who were treated with potentially curative gastrectomy and EIPL therapy between March 1995 and May 2013. D2 lymphadenectomy, R0 resection, and EIPL therapy were performed for all cases.
  
  
  RESULTS
  Multivariate analysis revealed that male gender (P = 0.01) and lymph node metastasis (P = 0.03) were independent prognostic factors, while positive cytology was not (P = 0.21). There was no significant difference in overall survival rates between the CY1/P0 and stage III B + C groups (P = 0.93). There was also no significant difference in peritoneal recurrence rates, i.e., 13 (35.1%) in the CY1/P0 group and 5 (21.7%) in the stage III B + C group (P = 0.39).
  
  
  CONCLUSIONS
  EIPL therapy combined with complete resection and sufficient (D2) lymphadenectomy could improve the prognosis of CY1/P0 gastric cancer and, to a similar extent, that of stage III B + C.
authors: Department of Surgery, Kumamoto General Hospital, Japan Community Health Care Organization, Kumamoto, 10-10 Tohri-cho, Yatsushiro, Kumamoto, 866-8660, Japan.
authors: Toshiro
authors: T
authors: Masuda
authors: Department of Surgery, Kumamoto General Hospital, Japan Community Health Care Organization, Kumamoto, 10-10 Tohri-cho, Yatsushiro, Kumamoto, 866-8660, Japan. kuramoto@kumamoto-gh.jp.
authors: Masafumi
authors: M
authors: Kuramoto
authors: Department of Surgery, Kumamoto General Hospital, Japan Community Health Care Organization, Kumamoto, 10-10 Tohri-cho, Yatsushiro, Kumamoto, 866-8660, Japan.
authors: Shinya
authors: S
authors: Shimada
authors: Department of Surgery, Kumamoto General Hospital, Japan Community Health Care Organization, Kumamoto, 10-10 Tohri-cho, Yatsushiro, Kumamoto, 866-8660, Japan.
authors: Satoshi
authors: S
authors: Ikeshima
authors: Department of Surgery, Kumamoto General Hospital, Japan Community Health Care Organization, Kumamoto, 10-10 Tohri-cho, Yatsushiro, Kumamoto, 866-8660, Japan.
authors: Kenichiro
authors: K
authors: Yamamoto
authors: Department of Surgery, Kumamoto General Hospital, Japan Community Health Care Organization, Kumamoto, 10-10 Tohri-cho, Yatsushiro, Kumamoto, 866-8660, Japan.
authors: Kenichi
authors: K
authors: Nakamura
authors: Department of Gastroenterology and Hepatology, Kumamoto General Hospital, Japan Community Health Care Organization, Kumamoto, 10-10 Tohri-cho, Yatsushiro, Kumamoto, 866-8660, Japan.
authors: Shinich
authors: S
authors: Yoshimatsu
authors: Department of Gastroenterology and Hepatology, Kumamoto General Hospital, Japan Community Health Care Organization, Kumamoto, 10-10 Tohri-cho, Yatsushiro, Kumamoto, 866-8660, Japan.
authors: Masayuki
authors: M
authors: Urata
authors: Department of Gastroenterological Surgery, Graduate School of Life Sciences, Kumamoto University, Kumamoto, 1-1-1, Honjo, Chuo-ku, Kumamoto, 860-0811, Japan.
authors: Hideo
authors: H
authors: Baba
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000556:secondary / Q000628:therapy*; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010533:Peritoneal Lavage / Q000379:methods*; D010534:Peritoneal Neoplasms / Q000401:mortality / Q000517:prevention & control* / Q000556:secondary; D011379:Prognosis; D012189:Retrospective Studies; D012737:Sex Factors; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D015996:Survival Rate
keywords: Carcinomatosis; Cytology; EIPL; Gastric cancer