title: Chondro-Osseous Lesions of Soft Tissue.
abstract: Soft tissue lesions can contain bone or cartilage matrix as an incidental, often metaplastic, phenomenon or as a diagnostic feature. The latter category includes a diverse group ranging from self-limited proliferations to benign neoplasms to aggressive malignancies. Correlating imaging findings with pathology is mandatory to confirm that a tumor producing bone or cartilage, in fact, originates from soft tissue rather than from the skeleton. The distinction can have dramatic diagnostic and therapeutic implications. This content focuses on the gross, histologic, radiographic, and clinical features of bone or cartilage-producing soft tissue lesions. Recent discoveries regarding tumor-specific genetics are discussed.
authors: Pathology, UCSF Medical Center Mission Bay, 1825 4th Street, Room M2354, San Francisco, CA 94158, USA.
authors: Soo-Jin
authors: SJ
authors: Cho
authors: Pathology, UCSF Medical Center Mission Bay, 1825 4th Street, Room M2354, San Francisco, CA 94158, USA. Electronic address: andrew.horvai@ucsf.edu.
authors: Andrew
authors: A
authors: Horvai
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D002812:Chondroma / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D003937:Diagnosis, Differential; D005350:Fibroma / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D020022:Genetic Predisposition to Disease; D006801:Humans; D009221:Myositis Ossificans / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D012516:Osteosarcoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D011379:Prognosis; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology
keywords: Chondroma; Myositis ossificans; Ossifying fibromyxoid tumor; Osteosarcoma; Synovial chondromatosis