Synthesis of functionalized tryptamines by Brønsted acid catalysed cascade reactions.
An original synthetic protocol has been developed for the preparation of highly functionalized tryptamines from 2-hydroxycyclobutanone and secondary arylamines via a solvent-free Brønsted acid catalysed two-step reaction sequence.
Dipartimento di Scienze Chimiche e Geologiche, Università degli studi di Cagliari, Complesso Universitario di Monserrato, S.S. 554, Bivio per Sestu, I-09042, Monserrato, Cagliari, Italy. afrongia@unica.it.
Nicola
N
Melis
Francesco
F
Secci
Thomas
T
Boddaert
David J
DJ
Aitken
Angelo
A
Frongia