Comprehensive Catalog of Currently Documented Histone Modifications.
Modern techniques in molecular biology, genomics, and mass spectrometry-based proteomics have identified a large number of novel histone posttranslational modifications (PTMs), many of whose functions are still under intense investigation. Here, we catalog histone PTMs under two classes: first, those whose functions have been fairly well studied and, second, those PTMs that have been more recently identified but whose functions remain unclear. We hope that this will be a useful resource for researchers from all biological or technical backgrounds, aiding in their chromatin and epigenetic pursuits.
Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois 60637.
Yingming
Y
Zhao
Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Benjamin A
BA
Garcia
D002377:Catalogs as Topic; D006657:Histones / Q000737:chemistry* / Q000235:genetics; D011499:Protein Processing, Post-Translational
D006657:Histones