Elderly patients have more infectious complications following laparoscopic colorectal cancer surgery.
OBJECTIVE
Elderly patients may be at higher risk of postoperative complications, particularly infective, than younger patients.


METHODS
We prospectively followed 163 consecutive patients undergoing elective laparoscopic resection for cancer. We compared patients < 65, 65-80 and > 80 years of age at the time of surgery.


RESULTS
Seventy (42.9%) patients had no complication; 93 (57.1%) had at least one complication following surgery and in 20 (12.3%) this was major. There was no difference in major complications between the groups (P = 0.47). Patients over 65 years of age were more likely to have a complication of any severity [< 65 years, 39.3%; 65-80 years, 69.3%; and > 80 years, 63.0% (P = 0.002)]. The frequency of gastrointestinal complications (30.1%) was similar in the groups (P = 0.29), as was wound infection (25.2%) (P = 0.65). There was an increase in the frequency of infectious complications, especially chest infection, with age, from 14.8% in patients < 65 years, to 22.7% in patients 65-80 years, to 44.4% in patients > 80 years (P = 0.01). Multivariate analysis showed no increase in overall complications in elderly patients, but Stage II or Stage III cancer (OR = 2.59, P = 0.04) and increasing body mass index (BMI) (OR = 1.07 for each unit increase in BMI, P = 0.04) were related to complications. Age remained the only predictor of an infective complication on multivariate analysis. Patients > 80 years of age had 4.21 times the OR of an infective complication (P = 0.03).


CONCLUSIONS
Older patients are more susceptible to infective complications postoperatively, particularly chest complications. Surgeons should alter their practice to reduce morbidity, such as adopting protocols requiring early physiotherapy.
Department of Colorectal Surgery, King's College Hospital, London, UK.
C L
CL
Kvasnovsky
Department of Colorectal Surgery, King's College Hospital, London, UK.
K
http://orcid.org/0000-0003-3187-1207
K
Adams
Department of Colorectal Surgery, King's College Hospital, London, UK.
M
M
Sideris
Department of Colorectal Surgery, King's College Hospital, London, UK.
J
J
Laycock
Department of Colorectal Surgery, King's College Hospital, London, UK.
A K
AK
Haji
Department of Colorectal Surgery, King's College Hospital, London, UK.
A
A
Haq
Department of Colorectal Surgery, King's College Hospital, London, UK.
J
J
Nunoo-Mensah
Department of Colorectal Surgery, King's College Hospital, London, UK.
S
S
Papagrigoriadis
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000453:epidemiology / Q000601:surgery*; D015897:Comorbidity; D013505:Digestive System Surgical Procedures; D005260:Female; D006801:Humans; D010535:Laparoscopy; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D009765:Obesity / Q000453:epidemiology*; D011014:Pneumonia / Q000453:epidemiology*; D011183:Postoperative Complications / Q000453:epidemiology*; D011446:Prospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology
ERAS; Laparoscopic surgery; colorectal cancer; complications; infections; safety