Occurrences and distribution of sulfonamide and tetracycline resistance genes in the Yangtze River Estuary and nearby coastal area.
The role of highly impacted estuaries needs to be examined with respect to the spread of antibiotic resistance genes in the environment. In the present study, sulfonamide resistance (sul), tetracycline resistance (tet) and class I integron (int1) genes were ubiquitous in the sediments of the Yangtze Estuary (YE) and nearby coastal area, and exhibited a declining trend from the inner estuary to the coast. Good relationships were only observed between int1 and sul1 genes, implying that int1 gene is essential to the proliferation of sul1 gene. A non-significant correlation between int1 and 16S rRNA genes indicated that the int1 gene came from pollution sources of ARGs instead of being intrinsic in environmental bacterial populations. Sulfonamides were rarely detected in the sediments of this region, so could not result in the production of sul genes in the local environment.
Zhujiang Hospital of Southern Medical University, Guangzhou 510282, PR China.
Lan
L
Lin
MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China.
Ke
K
Yuan
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, PR China.
Ximei
X
Liang
MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; South China Sea Resource Exploitation and Protection Collaborative Innovation Center, Sun Yat-Sen University, Guangzhou 510275, PR China.
Xin
X
Chen
Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Qingdao 266100, PR China.
Zongshan
Z
Zhao
MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; South China Sea Resource Exploitation and Protection Collaborative Innovation Center, Sun Yat-Sen University, Guangzhou 510275, PR China.
Ying
Y
Yang
MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; South China Sea Resource Exploitation and Protection Collaborative Innovation Center, Sun Yat-Sen University, Guangzhou 510275, PR China.
Shichun
S
Zou
MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; South China Sea Resource Exploitation and Protection Collaborative Innovation Center, Sun Yat-Sen University, Guangzhou 510275, PR China.
Tiangang
T
Luan
MOE Key Laboratory of Aquatic Product Safety, School of Marine Sciences, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Guangzhou 510275, PR China; South China Sea Resource Exploitation and Protection Collaborative Innovation Center, Sun Yat-Sen University, Guangzhou 510275, PR China. Electronic address: chenbw5@mail.sysu.edu.cn.
Baowei
B
Chen
D024881:Drug Resistance, Bacterial / Q000235:genetics*; D063366:Estuaries; D005798:Genes, Bacterial; D019015:Geologic Sediments / Q000382:microbiology*; D032023:Integrons; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D045483:Rivers / Q000382:microbiology; D000077145:Sulfanilamide; D013424:Sulfanilamides / Q000494:pharmacology*; D013752:Tetracycline / Q000032:analysis; D013753:Tetracycline Resistance / Q000235:genetics*
D012336:RNA, Ribosomal, 16S; D013424:Sulfanilamides; D000077145:Sulfanilamide; D013752:Tetracycline
Antibiotic resistance genes; Dissemination; Estuary; Integron