Lifestyle and dietary factors in relation to prostate cancer risk.
The aim of the present study was to determine the association between the socio-demographic, lifestyle factors, and dietary habits with the risk of prostate cancer (PC) in a case-control study of Spanish men. None of the socio-demographic, lifestyle or dietetic variables was found predictors of PC risk. Body mass index was associated with an increased risk for aggressive PC and fruit consumption with lower Gleason scores, thus less aggressive cancers. Nonetheless, after applying Bonferroni correction, these variables were not still associated with PC aggressiveness. More adequately, powered epidemiological studies that measure the effect of lifestyle and dietary intake in PC risk and aggressiveness are warranted to further elucidate the role of these modifiable factors on PC etiology.
a Laboratory of Genetic Identification , Legal Medicine and Toxicology Department, Faculty of Medicine, University of Granada , Granada , Spain .|b GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research) , Granada , Spain .
Maria Jesus
MJ
Alvarez-Cubero
c Service of Urology, University Hospital Virgen de las Nieves , Granada , Spain , and.
Manrique
M
Pascual-Geler
d Department of Nutrition and Food Science, Faculty of Pharmacy , University of Granada, Campus de Cartuja , Granada , Spain.
Ana
A
Rivas
b GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research) , Granada , Spain .
Luis Javier
LJ
Martinez-Gonzalez
a Laboratory of Genetic Identification , Legal Medicine and Toxicology Department, Faculty of Medicine, University of Granada , Granada , Spain .
Maria
M
Saiz
a Laboratory of Genetic Identification , Legal Medicine and Toxicology Department, Faculty of Medicine, University of Granada , Granada , Spain .|b GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research) , Granada , Spain .
Jose Antonio
JA
Lorente
c Service of Urology, University Hospital Virgen de las Nieves , Granada , Spain , and.
Jose Manuel
JM
Cozar
D000368:Aged; D016022:Case-Control Studies; D004032:Diet; D005247:Feeding Behavior; D006801:Humans; D008019:Life Style; D008297:Male; D011471:Prostatic Neoplasms / Q000209:etiology*; D012307:Risk Factors; D013030:Spain
Cancer risk; diet; lifestyle; prostate cancer