A near infrared colorimetric and fluorometric probe for organophosphorus nerve agent mimics by intramolecular amidation.
A near infrared probe for sensitive colorimetric and fluorimetric detection of nerve agent mimics, DCP and DCNP, was reported based on the activation of a carboxylic acid group by the mimics to conduct an intramolecular amidation reaction in the heptamethine chromophore, where its absorption or excitation maximum wavelength could be greatly red-shifted by attenuating the electron-donating ability of the amine group in the bridgehead site of heptamethine cyanine.
Department of Chemistry, College of Chemistry and Chemical Engineering, and the MOE Key Laboratory of Physical Laboratory of Spectrochemical Analysis & Instrumentation, Xiamen University, Xiamen, 361005, China. hzheng@xmu.edu.cn.
Xiao-Xiao
XX
Hu
Yue-Ting
YT
Su
Yun-Wei
YW
Ma
Xin-Qi
XQ
Zhan
Hong
H
Zheng
Yun-Bao
YB
Jiang
D000215:Acylation; D005456:Fluorescent Dyes / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D000067397:Nerve Agents / Q000032:analysis*; D063065:Organophosphonates / Q000032:analysis*; D009943:Organophosphorus Compounds / Q000032:analysis*
D005456:Fluorescent Dyes; D007211:Indoles; D000067397:Nerve Agents; D063065:Organophosphonates; D009943:Organophosphorus Compounds; C548970:diethylchlorophosphate; C561434:diethylcyanophosphonate