Rotavirus Infection: A Disease of the Past?
Rotavirus infection is the most common cause of severe diarrhea disease in infants and young children worldwide. Vaccination is the only control measure likely to have a significant impact on the incidence of severe disease. Rotavirus vaccines have reduced the burden of disease in the United States and Europe and vaccine programs are being introduced in Asia and Africa where it is hoped that vaccine will have significant impact on severe infection. Long-term monitoring and strain surveillance are needed to assess the effects of rotavirus immunization programs and to determine whether changes in strain ecology will affect rotavirus vaccine effectiveness.
Division of Pediatric Infectious Diseases, Department of Pediatrics, Hasbro Children's Hospital, 593 Eddy Street, Providence, RI 02903, USA. Electronic address: pdennehy@lifespan.org.
Penelope H
PH
Dennehy
D000349:Africa / Q000453:epidemiology; D001208:Asia / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005060:Europe / Q000453:epidemiology; D006801:Humans; D032521:Immunity, Herd; D017589:Immunization Programs; D015994:Incidence; D007223:Infant; D012401:Rotavirus / Q000276:immunology; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000008:administration & dosage; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
D022243:Rotavirus Vaccines
Rotavirus; Rotavirus gastroenteritis; Rotavirus immunity; Rotavirus surveillance; Rotavirus vaccine