Chronic sclerosing sialadenitis of the submandibular gland: an entity of IgG4-related sclerosing disease.
Chronic sclerosing sialadenitis typically involves the submandibular gland. It usually occurs in the middle-aged and elderly adults with a slight male predominance. Recent evidences have suggested that it is an entity of IgG4-related sclerosing disease and has distinct histopathological features, such as a dense lymphoplasmacytic infiltrate, sclerosis and obliterative phlebitis. It is important to discriminate this entity from other diseases, trying to give effective treatment to the patients. In this report, we described a patient having chronic sclerosing sialadenitis in the submandibular gland.
Department of Otolaryngology, E-DA Hospital, I-Shou University Kaohsiung, Taiwan.
Tzu-Wei
TW
Wei
Department of Otolaryngology, E-DA Hospital, I-Shou University Kaohsiung, Taiwan.
Ching-Feng
CF
Lien
Department of Otolaryngology, E-DA Hospital, I-Shou University Kaohsiung, Taiwan.
Tun-Yen
TY
Hsu
Department of Pathology, E-DA Hospital, I-Shou University Kaohsiung, Taiwan ; Institute of Biomedical Science, National Sun Yat-Sen University Kaohsiung, Taiwan.
Hong-Lin
HL
He
D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D012598:Sclerosis; D012793:Sialadenitis / Q000175:diagnosis* / Q000276:immunology / Q000601:surgery; D013363:Submandibular Gland / Q000276:immunology* / Q000473:pathology / Q000601:surgery; D013364:Submandibular Gland Diseases / Q000175:diagnosis* / Q000276:immunology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D015415:Biomarkers; D007074:Immunoglobulin G
Chronic sclerosing sialadenitis; IgG4; IgG4-related sclerosing disease