Influence of saline solution on hydration behavior of β-dicalcium silicate in comparison with biphasic calcium phosphate/hydroxyapatite bio-ceramics.
The influence of using saline solution as mixing and curing liquid on some characteristics of β-dicalcium silicate (β-C2S) and biphasic compound tri-calcium phosphate/hydroxyapatite (TCP/HAp) bio-ceramics was investigated. β-C2S (27-30 nm) was prepared by solid state reaction at 1450°C, while biphasic compound TCP/HAp (7-15 nm) was synthesized from an aqueous solution of Ca(NO3)2·4H2O and (NH4)2HPO4·12H2O by chemical precipitation method. Setting times, compressive strength, pH values, X-ray diffraction analysis, infrared spectroscopy, scanning electron microscopy (SEM) were investigated. The evaluation of cytotoxicity of both calcium silicate and biphasic compounds to human gingival fibroblasts was carried out. The use of saline solution as mixing and immersing liquid shortened the setting time for the two bio-cements. TCP/HAp did not show any mechanical strength but β-C2S showed good strength values. Both synthesized compounds showed a moderate cytotoxicity and both materials were effective in a no significant way.
Ceramics Dept, National Research Centre, Cairo, Egypt. Electronic address: mmahmoudradwan@yahoo.com.
M M
MM
Radwan
Ceramics Dept, National Research Centre, Cairo, Egypt.
H K
HK
Abd El-Hamid
The Holding Company for Production of Vaccines, Sera and Drugs (EGYVAC), Egypt.
A F
AF
Mohamed
D000818:Animals; D001826:Body Fluids / Q000737:chemistry*; D017610:Calcium Compounds / Q000737:chemistry* / Q000633:toxicity; D002130:Calcium Phosphates / Q000737:chemistry* / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D002516:Ceramics / Q000737:chemistry / Q000633:toxicity; D019245:Compressive Strength; D006224:Cricetinae; D017886:Durapatite / Q000737:chemistry* / Q000633:toxicity; D005347:Fibroblasts / Q000187:drug effects; D006244:Hardness; D006863:Hydrogen-Ion Concentration; D008422:Materials Testing; D017640:Silicates / Q000737:chemistry* / Q000633:toxicity; D012965:Sodium Chloride / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D017610:Calcium Compounds; D002130:Calcium Phosphates; D017640:Silicates; D014867:Water; C013481:dicalcium silicate; D012965:Sodium Chloride; D017886:Durapatite; C485829:calcium phosphate, dibasic, anhydrous
Bio-ceramics; Calcium phosphate; Calcium silicate; Cytotoxicity; Hydroxyapatite; Saline solution