GM-CSF stimulates granulopoiesis in a congenital neutropenia patient with loss-of-function biallelic heterozygous CSF3R mutations.
Department of Hematology, Oncology, Immunology, Rheumatology and Pulmonology, University Hospital Tuebingen, Tuebingen, Germany.
Maksim
M
Klimiankou
Department of Hematology, Oncology, Immunology, Rheumatology and Pulmonology, University Hospital Tuebingen, Tuebingen, Germany.
Olga
O
Klimenkova
Department of Experimental Hematology, Hannover Medical School, Hannover, Germany.
Murat
M
Uenalan
Department of Molecular Hematopoiesis, Hannover Medical School, Hannover, Germany.
Alexander
A
Zeidler
Department of Molecular Hematopoiesis, Hannover Medical School, Hannover, Germany.
Sabine
S
Mellor-Heineke
Department of Molecular Hematopoiesis, Hannover Medical School, Hannover, Germany.
Siarhei
S
Kandabarau
Department of Hematology, Oncology, Immunology, Rheumatology and Pulmonology, University Hospital Tuebingen, Tuebingen, Germany.
Julia
J
Skokowa
Department of Molecular Hematopoiesis, Hannover Medical School, Hannover, Germany.
Cornelia
C
Zeidler
Department of Pediatrics, University Hospital Tuebingen, Tuebingen, Germany.
Karl
K
Welte
D000483:Alleles; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D006098:Granulocytes / Q000166:cytology* / Q000187:drug effects; D006579:Heterozygote; D006801:Humans; D007231:Infant, Newborn; D019656:Loss of Heterozygosity; D009154:Mutation / Q000235:genetics*; D009503:Neutropenia / Q000151:congenital* / Q000188:drug therapy / Q000235:genetics*; D011379:Prognosis; D016184:Receptors, Colony-Stimulating Factor / Q000235:genetics*
C517047:CSF3R protein, human; D016184:Receptors, Colony-Stimulating Factor; D016178:Granulocyte-Macrophage Colony-Stimulating Factor