Association Between MCT1 A1470T Polymorphism and Fat-Free Mass in Well-Trained Young Soccer Players.
The aim of this study was to investigate the association between the MCT1 A1470T polymorphism and fat-free mass in young Italian elite soccer players. Participants were 128 Italian male soccer players. Fat-free mass was estimated for each of the soccer player using age- and gender-specific formulas with plicometry. Genotyping for the MCT1 A1470T polymorphism was performed using polymerase chain reaction. The MCT1 A1470T genotypes were in agreement with the Hardy-Weinberg equilibrium distribution. The percentage of fat-free mass was significantly higher in soccer players with the TT genotype and in the T-allele-dominant model group (TT + AT) compared with the soccer players with the AA genotype. The MCT1 T allele is associated with the percentage of fat-free mass in young elite male soccer players. Elucidating the genetic basis of body composition in athletes could potentially be used as an additional tool for strength and conditioning professionals in planning and adjusting training. However, these results are preliminary and need to be replicated in more cohorts.
1Department Life and Environmental Sciences, Cagliari University, Cagliari, Italy; 2Institute of Sport, Exercise and Active Living (ISEAL), Victoria University, Victoria, Australia; and 3FMSI CR Sardegna and Cagliari Calcio Spa, Cagliari, Italy.
Myosotis
M
Massidda
Nir
N
Eynon
Valeria
V
Bachis
Laura
L
Corrias
Claudia
C
Culigioni
Paolo
P
Cugia
Marco
M
Scorcu
Carla M
CM
Calò
D000293:Adolescent; D000483:Alleles; D001823:Body Composition; D050218:Body Fat Distribution; D003430:Cross-Sectional Studies; D005838:Genotype; D006801:Humans; D007558:Italy; D008297:Male; D027501:Monocarboxylic Acid Transporters / Q000235:genetics*; D011110:Polymorphism, Genetic; D012916:Soccer; D027981:Symporters / Q000235:genetics*; D055815:Young Adult; D000099233:Monocarboxylate Transport Protein 1
D027501:Monocarboxylic Acid Transporters; D027981:Symporters; D000099233:Monocarboxylate Transport Protein 1