A Pd8 Tetrafacial Molecular Barrel as Carrier for Water Insoluble Fluorophore.
A new carbazole-based tetraimidazole ligand 1,3,6,8-tetra(1H-imidazol-1-yl)-9-methyl-9H-carbazole (L) has been synthesized. The unsymmetrical nature of L as well as the rotational freedom of imidazole donor moieties around C-N bond make it a special building unit, which upon treatment with cis-(tmeda)Pd(NO3)2 produced an unprecedented single linkage-isomeric Pd8 tetrafacial molecular nanobarrel (PSMBR-1) [tmeda = N,N,N',N'-tetramethylethane-1,2-diamine]. Unlike closed architectures, open barrel architecture of water-soluble PSMBR-1 makes it an ideal host for some water insoluble polyaromatic hydrocarbons in aqueous medium; one such inclusion complex coronene⊂PSMBR-1 was characterized by X-ray diffraction study. Moreover, the potential application of PSMBR-1 as carrier in aqueous medium for the transportation of water insoluble fluorophore (perylene) for live cell imaging is explored.
Department of Inorganic and Physical Chemistry and ‡Department of Biochemistry, Indian Institute of Science , Bangalore 560012, India.
Bijan
B
Roy
Department of Inorganic and Physical Chemistry and ‡Department of Biochemistry, Indian Institute of Science , Bangalore 560012, India.
Aloke Kumar
AK
Ghosh
Department of Inorganic and Physical Chemistry and ‡Department of Biochemistry, Indian Institute of Science , Bangalore 560012, India.
Shubhi
S
Srivastava
Department of Inorganic and Physical Chemistry and ‡Department of Biochemistry, Indian Institute of Science , Bangalore 560012, India.
Patrick
P
D'Silva
Department of Inorganic and Physical Chemistry and ‡Department of Biochemistry, Indian Institute of Science , Bangalore 560012, India.
Partha Sarathi
PS
Mukherjee
D002227:Carbazoles / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D012995:Solubility; D014867:Water / Q000737:chemistry*
D002227:Carbazoles; D005456:Fluorescent Dyes; D008024:Ligands; D009942:Organometallic Compounds; D014867:Water; C041514:carbazole; D010165:Palladium