The Effect of Chronic Alcoholism on the Conjunctival Flora.
We aimed to investigate the effect of alcohol abuse on the conjunctival flora.



The cases were evaluated as two groups. The study group consisted of 55 heavy-drinking males diagnosed with alcohol abuse, while the control group consisted of 55 males without a history of alcohol abuse. Samples were taken from the inferior fornix conjunctiva with sterile cotton-tipped swabs (Amies transport medium) for culture. The samples were inoculated into blood agar, chocolate agar, eosine methylene blue agar and Saboraud-Dextrose agar (Oxoid/UK) with the dilution method.



The microorganisms that grew in study group subjects were Coagulase Negative Staphylococcus (CNS) in 30 (54.5%), Staphylococcus aureus in 14 (25.5%), Moraxella spp. in 3 (5.5%), Streptococcus spp. in 3 (5.5), Bacillus spp. in 3 (5.5%), Corynebacterium spp. in 3 (5.5%), Candida spp. in 3 (5.5%), Haemophilus spp. in 2 (3.6%), Acinetobacter spp. in 2 (3.6%), Neisseria spp. in 1 (1.8%) and Micrococcus spp. in 1 (1.8%). The results for control group were CNS in 31 (56.4%), Bacillus spp. in 7 (12.7%), S. aureus in 5 (9.1%), and Corynebacterium spp. in 2 (3.6%). Moraxella spp., Streptococcus spp., Candida spp., Haemophilus spp., Acinetobacter spp., Neisseria spp. and Micrococcus spp. microorganisms grew in the conjunctival flora samples of the study group but not in the control group. S. aureus colonization was significantly higher in the study group than the control group (p < 0.05).



The S. aureus colonization rate was statistically significantly higher in the study group. Some microorganisms only grew in the conjunctival flora samples of the study group. These findings indicate that the conjunctival flora in persons with chronic alcoholism is different than the normal population.
a Department of Ophthalmology .
Göksel
G
Gunduz
a Department of Ophthalmology .
Abuzer
A
Gunduz
a Department of Ophthalmology .
Nihat
N
Polat
b Department of Psychiatry , and.
Birgul Elbozan
BE
Cumurcu
c Department of Microbiology and Clinical Microbiology , Inonu University School of Medicine , Malatya , Turkey.
Yusuf
Y
Yakupogulları
D000328:Adult; D000437:Alcoholism / Q000150:complications*; D016022:Case-Control Studies; D002908:Chronic Disease; D015169:Colony Count, Microbial; D003228:Conjunctiva / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000209:etiology / Q000382:microbiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000209:etiology / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*
Alcoholism; S. aureus; conjunctival flora; ocular infections; ocular surgery