Ortho C-H Acylation of Aryl Iodides by Palladium/Norbornene Catalysis.
Reported herein is a palladium/norbornene-catalyzed ortho-arene acylation of aryl iodides by a Catellani-type C-H functionalization. This transformation is enabled by isopropyl carbonate anhydrides, which serve as both an acyl cation equivalent and a hydride source.
Department of Chemistry, University of Texas at Austin, 100 East 24th street, Austin, TX 78712 (USA) http://gbdong.cm.utexas.edu/
Zhe
Z
Dong
Department of Chemistry, University of Texas at Austin, 100 East 24th street, Austin, TX 78712 (USA) http://gbdong.cm.utexas.edu/
Jianchun
J
Wang
Department of Chemistry, University of Texas at Austin, 100 East 24th street, Austin, TX 78712 (USA) http://gbdong.cm.utexas.edu/
Zhi
Z
Ren
Department of Chemistry, University of Texas at Austin, 100 East 24th street, Austin, TX 78712 (USA) http://gbdong.cm.utexas.edu/. gbdong@cm.utexas.edu.
Guangbin
G
Dong
D000215:Acylation; D002384:Catalysis; D007454:Iodides / Q000737:chemistry*; D009636:Norbornanes / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
D007454:Iodides; D009636:Norbornanes; D010165:Palladium
CH activation; acylation; arenes; heterocycles; palladium