Rhesus Negative Woman Transfused With Rhesus Positive Blood: Subsequent Normal Pregnancy Without Anti D production.
Clinicians sometimes are confronted with the challenge of transfusing haemorrhaging Rhesus (Rh) D negative patients with Rh D positive blood to save their lives. There are concerns about alloimmunization and future haemolytic disease of the newborn in women of the reproductive age. Another fear is transfusion reaction if they receive another Rh D positive blood in future. We present a 32-year-old Rh D negative woman, who had postpartum haemorrhage in her first pregnancy and was transfused with Rh D positive blood because of unavailability of Rh D negative blood. She did not receive anti D immunoglobin but subsequently had a normal term pregnancy of an Rh positive fetus without any detectable anti D antibodies throughout the pregnancy. In life threatening situations from obstetric haemorrhage, transfusion of Rh D negative women with Rh D positive blood should be considered as the last resort.
School Of Public Health, University Of Ghana, Accra, Ghana.
E T
ET
Maya
Department of Obstetrics and Gynaecology, Ridge Regional Hospital, Accra, Ghana.
K A
KA
Buntugu
Department of Obstetrics and Gynaecology, Ridge Regional Hospital, Accra, Ghana.
F
F
Pobee
Department of Obstetrics and Gynaecology, Ridge Regional Hospital, Accra, Ghana.
E K
EK
Srofenyoh
D000328:Adult; D001803:Blood Transfusion / Q000379:methods*; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage; D007231:Infant, Newborn; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000276:immunology*; D012203:Rh Isoimmunization / Q000097:blood / Q000188:drug therapy*; D012204:Rh-Hr Blood-Group System / Q000276:immunology*; D018029:Rho(D) Immune Globulin / Q000008:administration & dosage / Q000097:blood*
D007155:Immunologic Factors; C061961:RHO(D) antibody; D012204:Rh-Hr Blood-Group System; D018029:Rho(D) Immune Globulin
Rhesus negative; alloimmunization; anti D immunoglobulin; blood transfusion; pregnancy