Amphetamine-induced psychosis: Transition to schizophrenia and mortality in a small prospective sample.
OBJECTIVE
We investigated transition from amphetamine-induced psychosis (AIP) to schizophrenia.


METHODS
A sample of 28 individuals was identified while hospitalized for AIP. We reviewed their hospital records after six years.


RESULTS
During follow-up, seven individuals (25%) died and nine (32%) had moved from the area. Of the remaining 12, four individuals (25%) were diagnosed with schizophrenia. These individuals were, at baseline, characterized by fewer hallucinatory symptoms and more homelessness.


CONCLUSIONS
Hospitalization for AIP was a relatively specific risk factor for schizophrenia and the mortality rate in AIP was high.
Norwegian Centre for Addiction Research (SERAF), University of Oslo, Norway.|Lovisenberg Diakonale Hospital, Oslo, Norway.
Sigrid
S
Medhus
Norwegian Centre for Addiction Research (SERAF), University of Oslo, Norway.|Oslo University Hospital, Norway.|Norwegian National Advisory Unit on Concurrent Substance Abuse and Mental Health Disorders, Norway.
Eline Borger
EB
Rognli
Norwegian Centre for Addiction Research (SERAF), University of Oslo, Norway.|Kings College London, National Addiction Centre, London, UK.
Michael
M
Gossop
Lovisenberg Diakonale Hospital, Oslo, Norway.
Bjørn
B
Holm
Norwegian Institute of Public Health, Oslo, Norway.
Jørg
J
Mørland
Norwegian Centre for Addiction Research (SERAF), University of Oslo, Norway.
Jørgen G
JG
Bramness
D000661:Amphetamine / Q000633:toxicity*; D018450:Disease Progression; D006801:Humans; D009664:Norway / Q000453:epidemiology; D011446:Prospective Studies; D011605:Psychoses, Substance-Induced / Q000453:epidemiology* / Q000401:mortality*; D012307:Risk Factors; D012559:Schizophrenia / Q000453:epidemiology* / Q000401:mortality*
D000661:Amphetamine