Pulmonary scedosporiosis mimicking aspergilloma in an immunocompetent host: a case report and review of the literature.
A case of localized lung scedosporiosis is reported here that mimicked aspergilloma in an immunocompetent host. Through this case the importance of considering Scedosporium spp. in differential diagnosis of locally invasive lung infections and fungal ball is highlighted. As it is difficult to differentiate Scedosporium from Aspergillus on clinical grounds, microscopy, radiology and histopathology, this case is further emphasizing the significance of the definitive etiological characterization of Scedosporium through culture or molecular diagnostic tools. Accurate identification of Scedosporium, surgical resection and high-dose voriconazole has been associated with favorable outcome in most reported cases of scedosporiosis.
Section of Pulmonary and Critical Care Medicine, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Fasih Ur
FU
Rahman
Section of Pulmonary and Critical Care Medicine, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Muhammad
M
Irfan
Department of Pathology and Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan. fasihnaima@gmail.com.
Naima
N
Fasih
Department of Pathology and Microbiology, Aga Khan University Hospital, Stadium Road, Karachi, 74800, Pakistan.
Kauser
K
Jabeen
Cardio-Thoracic Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Hasanat
H
Sharif
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000473:pathology*; D003646:Debridement; D003937:Diagnosis, Differential; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D008297:Male; D021681:Scedosporium / Q000302:isolation & purification*; D065819:Voriconazole / Q000627:therapeutic use
D000935:Antifungal Agents; D065819:Voriconazole
Aspergilloma; Lung scedosporiosis; Pulmonary scedosporiosis; Scedosporiosis; Scedosporiosis in an immunocompetent host; Scedosporium apiospermum; Treatment of scedosporiosis; Voriconazole