Percutaneous Image-Guided Cryoablation of Breast Cancer: A Systematic Review.
A systematic review of the clinical safety and efficacy of percutaneous breast cancer cryoablation was performed. Of 202 papers screened, seven matched the inclusion criteria. Cryoablation was mainly performed under ultrasound guidance, and on average two cryoprobes were used. Complete local tumor control was noted in 73% of patients (mean follow-up, 8 mo). No major complications were noted. The cosmetic outcome was satisfactory. Breast cancer cryoablation is safe, although local tumor control is suboptimal. The best results are achieved with small (<15 mm) ductal tumors treated by application of multiple cryoprobes.
Department of Radiology, Humanitas Research Hospital, Via Alessandro Manzoni, 56, Rozzano 20089, Italy. Electronic address: eziolanza@gmail.com.
Ezio
E
Lanza
Department of Radiology, Institut Bergonié, Bordeaux, France.
Jean
J
Palussiere
Department of Radiology, Institut Bergonié, Bordeaux, France.
Xavier
X
Buy
Department of Radiology, Università "Campus Bio-Medico di Roma," Rome, Italy.
Rosario Francesco
RF
Grasso
Department of Radiology, Università "Campus Bio-Medico di Roma," Rome, Italy.
Bruno
B
Beomonte Zobel
Department of Radiology, Humanitas Research Hospital, Via Alessandro Manzoni, 56, Rozzano 20089, Italy.
Dario
D
Poretti
Department of Radiology, Humanitas Research Hospital, Via Alessandro Manzoni, 56, Rozzano 20089, Italy.
Vittorio
V
Pedicini
Department of Radiology, Humanitas Research Hospital, Via Alessandro Manzoni, 56, Rozzano 20089, Italy.
Luca
L
Balzarini
Department of Radiology, Università "Campus Bio-Medico di Roma," Rome, Italy.
Roberto Luigi
RL
Cazzato
D001943:Breast Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery*; D003452:Cryosurgery / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000706:statistics & numerical data*; D008875:Middle Aged; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D025321:Surgery, Computer-Assisted / Q000706:statistics & numerical data*; D016896:Treatment Outcome