Characterizing the Switching Thresholds of Magnetophoretic Transistors.
The switching thresholds of magnetophoretic transistors for sorting cells in microfluidic environments are characterized. The transistor operating conditions require short 20-30 mA pulses of electrical current. By demonstrating both attractive and repulsive transistor modes, a single transistor architecture is used to implement the full write cycle for importing and exporting single cells in specified array sites.
Department of Mechanical Engineering and Materials Science, Duke University, Box 90300 Hudson Hall, Durham, NC, 27708, USA.
Roozbeh
R
Abedini-Nassab
Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Daniel Y
DY
Joh
Department of Medicine, Duke University, Durham, NC, 27708, USA.
Melissa A
MA
Van Heest
Department of Medicine, Duke University, Durham, NC, 27708, USA.
John S
JS
Yi
Department of Mechanical Engineering and Materials Science, Duke University, Box 90300 Hudson Hall, Durham, NC, 27708, USA.
Cody
C
Baker
Department of Mechanical Engineering and Materials Science, Duke University, Box 90300 Hudson Hall, Durham, NC, 27708, USA.
Zohreh
Z
Taherifard
Division of Infectious Diseases, Center for AIDS Research Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
David M
DM
Margolis
Division of Infectious Diseases, Center for AIDS Research Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
J Victor
JV
Garcia
Department of Mechanical Engineering and Materials Science, Duke University, Box 90300 Hudson Hall, Durham, NC, 27708, USA.|Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Ashutosh
A
Chilkoti
Department of Medicine, Duke University, Durham, NC, 27708, USA.
David M
DM
Murdoch
Department of Mechanical Engineering and Materials Science, Duke University, Box 90300 Hudson Hall, Durham, NC, 27708, USA.|Department of Biomedical Engineering, Duke University, Durham, NC, 27708, USA.
Benjamin B
BB
Yellen
D015704:CD4 Antigens / Q000378:metabolism; D004867:Equipment Design; D020342:Finite Element Analysis; D006801:Humans; D060328:Magnetic Phenomena; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods; D008962:Models, Theoretical; D066330:Printing, Three-Dimensional; D012666:Semiconductors; D013601:T-Lymphocytes / Q000166:cytology / Q000502:physiology
D015704:CD4 Antigens
magnetism; microfabrication; microfluidics; single cells; transistors