Gadofosveset trisodium-enhanced MR angiography for detection of lower gastrointestinal bleeding.
The purpose of our study is to determine if Gadofosveset trisodium-enhanced magnetic resonance angiography (MRA) could be used for detection and localization of acute lower gastrointestinal (LGI) bleed. Four patients underwent MRA (4 females, mean age of 65 years) for suspected LGI bleeding. MRA detected an active rectal bleed in one patient. All other patients did not demonstrate active bleeding and these true negatives were confirmed by computed tomography angiography, endoscopy, and tagged-red blood cell scan or digital subtraction angiography. Preliminary results suggest that MRA may serve as an alternative technique for detecting acute LGI bleeding when nuclear scintigraphy is unavailable or in the younger radiosensitive population but further investigation in a larger cohort is required.
Department of Radiology, Columbia University Medical Center, New York, NY, USA.
Robert F
RF
Hanna
Department of Radiology, Columbia University Medical Center, New York, NY, USA.
William F
WF
Browne
Department of Internal Medicine, Division of Digestive and Liver Disease, Columbia University Medical Center, New York, NY, USA.
Lauren G
LG
Khanna
Department of Radiology, Columbia University Medical Center, New York, NY, USA; Department of Radiology, Weill Cornell Medical College, New York, NY, USA.
Martin R
MR
Prince
Department of Radiology, Columbia University Medical Center, New York, NY, USA. Electronic address: ehecht@columbia.edu.
Elizabeth M
EM
Hecht
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction / Q000379:methods*; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008875:Middle Aged; D009942:Organometallic Compounds
D003287:Contrast Media; D009942:Organometallic Compounds; D005682:Gadolinium; C109932:gadofosveset trisodium
Bowel imaging; Gadolinium chelate agents; Gastrointestinal bleeding; MR angiography; MRI