MicroCT Analysis of Micro-Nano Titanium Implant Surface on the Osseointegration.
This study was to investigate the effects of micro-nano titanium implant surface on the osseointegration. A total of 36 screw-shaped implants were used. The implant surfaces were classified into 3 groups (n = 12): machined surface (M group), nanosurface which is nanotube formation on the machined surface (MA group) and nano-micro surface which is nanotube formation on the RBM surface (RA group). Anodic oxidation was performed at a 20 V for 10 min with 1 M H3PO4 and 1.5 wt% HF solutions. The implants were installed on the humerus on 6 beagles. After 4 and 12 weeks, the morphometric analysis with micro CT (skyscan 1172, SKYSCAN, Antwerpen, Belgium) was done. The data were statistically analyzed with two-way ANOVA. Bone mineral density and bone volume were significantly increased depending on time. RA group showed the highest bone mineral density and bone volume at 4 weeks and 12 weeks significantly. It indicated that nano-micro titanium implant surface showed faster and more mature osseointegration.
Jaesam
J
Ban
Seongsoo
S
Kang
Jihyun
J
Kim
Kwangmin
K
Lee
Lim
L
Hyunpil
Mongsook
M
Vang
Hongso
H
Yang
Gyejeong
G
Oh
Hyunseung
H
Kim
Gabwoon
G
Hwang
Yongho
Y
Jung
Kyungku
K
Lee
Sangwon
S
Park
Kwidug
K
Yunl
D000818:Animals; D018786:Bone Substitutes / Q000737:chemistry* / Q000494:pharmacology*; D004285:Dogs; D006811:Humerus / Q000601:surgery; D008297:Male; D043942:Nanotubes / Q000737:chemistry*; D016348:Osseointegration / Q000187:drug effects*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*; D055114:X-Ray Microtomography
D018786:Bone Substitutes; D014025:Titanium