Full genome sequences of torque teno sus virus strains that coinfected a pig with postweaning multisystemic wasting syndrome in Japan: implications for genetic diversity.
We determined the complete genome sequences of torque teno sus viruses (TTSuVs) detected in pigs with postweaning multisystemic wasting syndrome (PMWS) and in healthy pigs in Japan. Unexpectedly, we found coinfection of a PMWS-affected pig in Japan with one strain of TTSuV1, five strains of TTSuV2, and one strain of PCV2. Full-genome sequencing of each of these strains, followed by phylogenetic analysis, revealed broad genetic diversity in the TTSuV2 strains infecting the PMWS-affected pig. These results suggest that the geographical bias in the available genetic information about TTSuVs has a limited impact on the evaluation of their genetic diversity.
Laboratory of Animal Hygiene, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0065, Japan. mozawa@vet.kagoshima-u.ac.jp.|Transboundary Animal Diseases Control and Research Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan. mozawa@vet.kagoshima-u.ac.jp.|United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan. mozawa@vet.kagoshima-u.ac.jp.
Makoto
M
Ozawa
Transboundary Animal Diseases Control and Research Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Toshiko
T
Kawabata
Laboratory of Animal Hygiene, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0065, Japan.
Kosuke
K
Okuya
Transboundary Animal Diseases Control and Research Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Kiori
K
Nagano
Laboratory of Animal Hygiene, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0065, Japan.
Takehiro
T
Kanda
Laboratory of Animal Hygiene, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0065, Japan.
Norihiro
N
Kanazawa
Laboratory of Animal Hygiene, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0065, Japan.|Transboundary Animal Diseases Control and Research Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.|United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.
Kyoko
K
Tsukiyama-Kohara
Vaxxinova Japan K.K., Tokyo, Japan.
Akira
A
Taneno
Laboratory of Animal Hygiene, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima, 890-0065, Japan.|United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.|Laboratory of Farm Animal Production Medicine, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Eisaburo
E
Deguchi
D000818:Animals; D001483:Base Sequence; D017925:Circovirus / Q000235:genetics / Q000502:physiology*; D060085:Coinfection / Q000662:veterinary* / Q000821:virology; D014644:Genetic Variation; D016679:Genome, Viral; D007564:Japan; D008969:Molecular Sequence Data; D010802:Phylogeny; D053570:Porcine Postweaning Multisystemic Wasting Syndrome / Q000821:virology*; D013552:Swine; D022783:Torque teno virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D014764:Viral Proteins / Q000235:genetics
D014764:Viral Proteins