Successful treatment of multiresistant Achromobacter xylosoxidans bacteremia in a child with acute myeloid leukemia.
Achromobacter xylosoxidans is an aerobic gram-negative bacillus and important cause of bacteremia in immunocompromised patients. We describe a leukemia pediatric patient with severe neutropenia who developed bacteremia with A xylosoxidans resistant to multiple antibiotics, and treated the patient with tigecycline and piperacillin-tazobactam in addition to supportive medications.
Dr Deniz Tugcu, Kanuni Sultan Suleyman Training and Research Hospital, Department of Pediatric Haematology- Oncology, Turgut Özal Cd. No:1 Halkal, Küçükçekmece, Istanbul 34306, Turkey, T: +90 532 2860318, F: + 0212 571 47 90, deniztugcu@superonline.com.
Deniz
D
Tugcu
Ozden
O
Turel
Gonul
G
Aydogan
Arzu
A
Akcay
Zafer
Z
Salcioglu
Ferhan
F
Akici
Hulya
H
Sen
Metin
M
Demirkaya
Necati
N
Taskin
Nezahat
N
Gurler
D042441:Achromobacter denitrificans / Q000302:isolation & purification; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D008911:Minocycline / Q000008:administration & dosage / Q000031:analogs & derivatives; D009503:Neutropenia / Q000473:pathology; D010397:Penicillanic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives; D010878:Piperacillin / Q000008:administration & dosage; D000077725:Piperacillin, Tazobactam Drug Combination; D000078304:Tigecycline
D000900:Anti-Bacterial Agents; D000077725:Piperacillin, Tazobactam Drug Combination; D000078304:Tigecycline; D010397:Penicillanic Acid; D008911:Minocycline; D010878:Piperacillin