Suicidal Zinc Phosphide Poisoning Unmasking Brugada Syndrome and Triggering Near Fatal Ventricular Arrhythmia.
Brugada syndrome (BrS) is an inherited channelopathy associated with increased incidence of ventricular arrhythmias and has many acquired triggers. Zinc phosphide (ZnP) is a rodenticide and is commonly implicated in suicidal poison ingestion. ZnP poisoning can cause myocardial toxicity and death. We report a case of ZnP poisoning that triggered a type I Brugada pattern and ventricular fibrillation in a 67-year-old male. He had no other features of toxicity and recovered later. As metal phosphide is the commonest toxin involved in suicidal poisoning in India and BrS being endemic here, this case highlights an important clinical problem.
Department of Cardiology, Electrophysiology Unit, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India.
Mukund A
MA
Prabhu
Department of Cardiology, Electrophysiology Unit, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India.
Reynold
R
Agustinus
Department of Cardiology, Electrophysiology Unit, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, India.
Jayaprakash
J
Shenthar
D000368:Aged; D053840:Brugada Syndrome / Q000139:chemically induced*; D004562:Electrocardiography; D006801:Humans; D007194:India; D008297:Male; D010720:Phosphines / Q000506:poisoning*; D013406:Suicide, Attempted; D014693:Ventricular Fibrillation / Q000139:chemically induced*; D017967:Zinc Compounds / Q000506:poisoning*
D010720:Phosphines; D017967:Zinc Compounds; C009701:zinc phosphide
Brugada syndrome; ventricular fibrillation; zinc phosphide