Pd(OAc)2-catalysed regioselective alkoxylation of aryl (β-carbolin-1-yl)methanones via β-carboline directed ortho-C(sp(2))-H activation of an aryl ring.
Synthesis of (2-alkoxyphenyl)(9H-pyrido[3,4-b]indol-1-yl)methanone via Pd(OAc)2-catalyzed regioselective alkoxylation of aryl (β-carbolin-1-yl) methanones employing β-carboline directed ortho-C(sp(2))-H activation of an aryl ring under oxidative conditions is described.
Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow-226031, UP, India. batra_san@yahoo.co.uk s_batra@cdri.res.in.
Shivalinga
S
Kolle
Sanjay
S
Batra
D000085:Acetates / Q000737:chemistry*; D000438:Alcohols / Q000737:chemistry*; D002243:Carbolines / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis*; D013237:Stereoisomerism
D000085:Acetates; D000438:Alcohols; D002243:Carbolines; D007211:Indoles; D009942:Organometallic Compounds; D011725:Pyridines; C059688:alkoxyl radical; C516071:palladium(II) acetate; C010262:norharman