On the mechanical properties of PLC-bioactive glass scaffolds fabricated via BioExtrusion.
This paper addresses the mechanical characterization of polycaprolactone (PCL)-bioglass (FastOs®BG) composites and scaffolds intended for use in tissue engineering. Tissue engineering scaffolds support the self-healing mechanism of the human body and promote the regrowth of damaged tissue. These implants can dissolve after successful tissue regeneration minimising the immune reaction and the need for revision surgery. However, their mechanical properties should match surrounding tissue in order to avoid strain concentration and possible separation at the interface. Therefore, an extensive experimental testing programme of this advanced material using uni-axial compressive testing was conducted. Tests were performed at low strain rates corresponding to quasi-static loading conditions. The initial elastic gradient, plateau stress and densification strain were obtained. Tested specimens varied according to their average density and material composition. In total, four groups of solid and robocast porous PCL samples containing 0, 20, 30, and 35% bioglass, respectively were tested. The addition of bioglass was found to slightly decrease the initial elastic gradient and the plateau stress of the biomaterial scaffolds.
Discipline of Mechanical Engineering, The University of Newcastle, Callaghan, NSW 2308, Australia. Electronic address: Thomas.Fiedler@newcastle.edu.au.
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Fiedler
Department of Materials and Ceramic Engineering, University of Aveiro, CICECO, 3810-193 Aveiro, Portugal; Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria (IPL), Leiria, Portugal.
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Videira
Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria (IPL), Leiria, Portugal.
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Bártolo
Discipline of Mechanical Engineering, The University of Newcastle, Callaghan, NSW 2308, Australia.
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M
Strauch
Discipline of Mechanical Engineering, The University of Newcastle, Callaghan, NSW 2308, Australia.
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Murch
Department of Materials and Ceramic Engineering, University of Aveiro, CICECO, 3810-193 Aveiro, Portugal.
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Ferreira
D018786:Bone Substitutes / Q000138:chemical synthesis*; D002516:Ceramics / Q000737:chemistry*; D019245:Compressive Strength; D055119:Elastic Modulus; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006244:Hardness; D008422:Materials Testing; D011091:Polyesters / Q000737:chemistry*; D013314:Stress, Mechanical; D013718:Tensile Strength; D023822:Tissue Engineering / Q000295:instrumentation*; D054457:Tissue Scaffolds
C022107:Bioglass; D018786:Bone Substitutes; D011091:Polyesters; C016240:polycaprolactone
FastOs®BG; Mechanical properties; Polycaprolactone (PCL); Robocasting; Scaffolds