Recent advances in chemiluminescence detection coupled with capillary electrophoresis and microchip capillary electrophoresis.
CE is an ideal analytical method for extremely volume-limited biological microenvironments. However, the small injection volume makes it a challenge to achieve highly sensitive detection. Chemiluminescence (CL) detection is characterized by providing low background with excellent sensitivity because of requiring no light source. The coupling of CL with CE and MCE has become a powerful analytical method. So far, this method has been widely applied to chemical analysis, bioassay, drug analysis, and environment analysis. In this review, we first introduce some developments for CE-CL and MCE-CL systems, and then put the emphasis on the applications in the last 10 years. Finally, we discuss the future prospects.
State Key Laboratory of Metal Matrix Composites, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, P. R. China.
Yuxuan
Y
Liu
State Key Laboratory of Metal Matrix Composites, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, P. R. China.
Xiangyi
X
Huang
State Key Laboratory of Metal Matrix Composites, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, P. R. China.
Jicun
J
Ren
D019075:Electrophoresis, Capillary; D046209:Electrophoresis, Microchip; D008163:Luminescent Measurements
Capillary electrophoresis; Chemiluminescence detection; Microchip capillary electrophoresis