Synchronous double primary gastric and endometrial cancer: a case report and literature review.
Multiple primary malignant neoplasms (MPMN) are two or more malignancies in an individual without any relationship between the tumors. In recent years, increasing number of cases were reported. However, Synchronous double primary gastric and endometrial cancer are relatively rare to be reported. Here we present a rare case of synchronous double cancer involving the stomach and endometrium, which is resected simultaneously and received six times chemo. After reviewing lots of literatures at home and abroad, we discuss the risk factors, the diagnostic criteria, the treatment modalities and the prognosis of these rare MPMN. Although a number of risk factors have been proposed in a mass of literatures, but the mechanism of MPMN is still unclear. We didn't discover a detailed explanation for the mechanism of MPMN from our patient. Therefore, further research should focus on the etiology and mechanism of MPMN.
Department of Surgical Oncology, Gansu Provincial Hospital Lanzhou 730000, Peoples Republic of China.
Mingxu
M
Da
Department of Surgery, Ningxia Medical University Yinchuan 750000, Peoples Republic of China.
Lingzhi
L
Peng
Department of Surgical Oncology, Gansu Provincial Hospital Lanzhou 730000, Peoples Republic of China.
Yongbin
Y
Zhang
Department of Surgical Oncology, Gansu Provincial Hospital Lanzhou 730000, Peoples Republic of China.
Jibin
J
Yao
Department of Surgical Oncology, Gansu Provincial Hospital Lanzhou 730000, Peoples Republic of China.
Yaoxing
Y
Duan
Department of Surgery, Ningxia Medical University Yinchuan 750000, Peoples Republic of China.
Yanghui
Y
Wen
D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D016889:Endometrial Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D005260:Female; D005743:Gastrectomy / Q000379:methods; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D007150:Immunohistochemistry; D010535:Laparoscopy; D008197:Lymph Node Excision; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D013274:Stomach Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
D014408:Biomarkers, Tumor
Synchronous; endometrial cancer; gastric cancer; multiple primary malignant neoplasms (MPMN)