Use of anti-mullerian hormone for testing ovarian reserve: a survey of 796 infertility clinics worldwide.
OBJECTIVE
The aim of this study is to assess how anti-mullerian hormone (AMH) is used worldwide to test ovarian reserve and guide in vitro fertilization (IVF) cycle management.


METHODS
An internet-based survey was sent electronically to registered IVF providers within the IVF-Worldwide.com network. This survey consisted of nine questions which assessed the clinics' use of AMH. The questionnaire was completed online through the IVF-Worldwide.com website, and quality assurance tools were used to verify that only one survey was completed per clinical IVF center. Results are reported as the proportion of IVF cycles represented by a particular answer choice.


RESULTS
Survey responses were completed from 796 globally distributed IVF clinics, representing 593,200 IVF cycles worldwide. Sixty percent of the respondent-IVF cycles reported to use AMH as a first line test, and 54 % reported it as the best test for evaluating ovarian reserve. Eighty-nine percent reported that AMH results were extremely relevant or relevant to clinical practice. However in contrast, for predicting live birth rate, 81 % reported age as the best predictor.


CONCLUSIONS
AMH is currently considered a first line test for evaluating ovarian reserve and is considered relevant to clinical practice by the majority of IVF providers.
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Womack Army Medical Center, Fort Bragg, NC, USA. kyle.tobler@gmail.com.
Kyle J
KJ
Tobler
Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Gon
G
Shoham
Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mindy S
MS
Christianson
Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Yulian
Y
Zhao
The Women's Clinic, Hong Kong, SAR, China.
Milton
M
Leong
Department of Obstetrics & Gynaecology, Kaplan Medical Center, Rehovot, Israel.|Hadassah Medical School, Jerusalem, Israel.
Zeev
Z
Shoham
D054304:Anti-Mullerian Hormone / Q000097:blood*; D001723:Birth Rate; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D008423:Maternal Age; D065851:Ovarian Reserve / Q000502:physiology*; D011247:Pregnancy; D018456:Reproductive Medicine / Q000379:methods; D011795:Surveys and Questionnaires
D054304:Anti-Mullerian Hormone
Anti-mullerian hormone; IVF; IVF-Worldwide; Ovarian reserve; Survey