[Shugan Yiyang Capsules for the treatment of asthenospermia: A clinical study].
OBJECTIVE
To observe the clinical efficacy of Shugan Yiyang Capsules in the treatment of asthenospermia and its action mechanisms.


METHODS
We randomly assigned 135 asthenospermia patients to groups A (n = 47), B (n = 45), and C (n = 43) to be treated with Shugan Yiyang Capsules, oral levocarnitine, or combination of the two. We observed sperm quality and the level of α-glucosidase in the seminal plasma before and after medication.


RESULTS
The total effectiveness rate was 70.21% in group A (markedly effective in 16 cases and effective in 17), 68.89% in group B (markedly effective in 15 cases and effective in 16), and 83.72% in group C (markedly effective in 16 cases and effective in 20), significantly higher in C than in A and B (P < 0.05). Both sperm quality and the level of α-glucosidase in the seminal plasma were improved in the three groups of patients, most obviously in group C.


CONCLUSIONS
Shugan Yiyang Capsules can be used for the treatment of asthenospermia, and its effect can be enhanced in combination with oral levocarnitine.
Ya-lei
YL
Shi
Min-jian
MJ
Zhang
Wan-jun
WJ
Cheng
Yang-fan
YF
Ou
D053627:Asthenozoospermia / Q000188:drug therapy* / Q000201:enzymology; D035843:Biomedical Research; D002214:Capsules; D002331:Carnitine / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D012661:Semen / Q000201:enzymology; D013094:Spermatozoa; D000520:alpha-Glucosidases / Q000032:analysis
D002214:Capsules; D004365:Drugs, Chinese Herbal; D000520:alpha-Glucosidases; D002331:Carnitine