Maintaining What Is Already There: Strategies to Rectify HSC Transplantation Dilemmas.
Hematopoietic stem cell (HSC) transplantation remains the only cure for various hematological diseases, but low HSC numbers in many donor samples are a critical problem preventing their clinical use. Now in Nature and Cell, two creative strategies to rescue and improve pre-existing engraftment potential are presented.
Regeneration in Hematopoiesis and Animal Models in Hematopoiesis, Institute for Immunology, Faculty of Medicine, TU Dresden, Fetscherstrasse 74, 01307 Dresden, Germany. Electronic address: claudia.waskow@tu-dresden.de.
Claudia
C
Waskow
D015126:8,11,14-Eicosatrienoic Acid / Q000031:analogs & derivatives*; D000818:Animals; D001853:Bone Marrow; D005260:Female; D005312:Fetal Blood / Q000166:cytology*; D006410:Hematopoiesis; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D008297:Male; D015027:Zebrafish / Q000196:embryology*
D015126:8,11,14-Eicosatrienoic Acid