Superiority trials: raising the bar of null hypothesis statistical testing.
We propose a ‘superiority margin’, akin to the noninferiority margin used in non-inferiority trials. This would overcome several drawbacks of null hypothesis statistical testing and can be applicable to other types of analyses as well.
Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Nusrat
N
Shafiq
Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Samir
S
Malhotra
D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D003627:Data Interpretation, Statistical; D006801:Humans; D012107:Research Design / Q000706:statistics & numerical data
CLINICAL PHARMACOLOGY