Signaling involved in stem cell reprogramming and differentiation.
Stem cell differentiation is regulated by multiple signaling events. Recent technical advances have revealed that differentiated cells can be reprogrammed into stem cells. The signals involved in stem cell programming are of major interest in stem cell research. The signaling mechanisms involved in regulating stem cell reprogramming and differentiation are the subject of intense study in the field of life sciences. In this review, the molecular interactions and signaling pathways related to stem cell differentiation are discussed.
Shihori Tanabe, National Institute of Health Sciences, Tokyo 158-8501, Japan.
Shihori
S
Tanabe
Differentiation; Gene; Genome; Reprogramming; Signaling; Stem cell