New horizon for high performance Mg-based biomaterial with uniform degradation behavior: Formation of stacking faults.
Designing the new microstructure is an effective way to accelerate the biomedical application of magnesium (Mg) alloys. In this study, a novel Mg-8Er-1Zn alloy with profuse nano-spaced basal plane stacking faults (SFs) was prepared by combined processes of direct-chill semi-continuous casting, heat-treatment and hot-extrusion. The formation of SFs made the alloy possess outstanding comprehensive performance as the biodegradable implant material. The ultimate tensile strength (UTS: 318 MPa), tensile yield strength (TYS: 207 MPa) and elongation (21%) of the alloy with SFs were superior to those of most reported degradable Mg-based alloys. This new alloy showed acceptable biotoxicity and degradation rate (0.34 mm/year), and the latter could be further slowed down through optimizing the microstructure. Most amazing of all, the uniquely uniform in vitro/vivo corrosion behavior was obtained due to the formation of SFs. Accordingly we proposed an original corrosion mechanism for the novel Mg alloy with SFs. The present study opens a new horizon for developing new Mg-based biomaterials with highly desirable performances.
Key Laboratory of Superlight Materials &Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
Jinghuai
J
Zhang
Key Laboratory of Superlight Materials &Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
Chi
C
Xu
Department of orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.|The Key Laboratory of Myocardial Ischemia, Harbin Medical University, Ministry of Education, Heilongjiang Province, China.
Yongbin
Y
Jing
School of Materials Science and Engineering, Changchun University of Science and Technology, Changchun 130022, China.
Shuhui
S
Lv
Department of Materials Physics and Chemistry, Harbin Institute of Technology, Harbin 150001, China.
Shujuan
S
Liu
School of Materials Science and Engineering, Taiyuan University of Science and Technology, Taiyuan, 030024, China.
Daqing
D
Fang
Department of orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
Jinpeng
J
Zhuang
Key Laboratory of Superlight Materials &Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
Milin
M
Zhang
Key Laboratory of Superlight Materials &Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
Ruizhi
R
Wu
D000497:Alloys / Q000737:chemistry; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D003343:Corrosion; D008274:Magnesium / Q000737:chemistry*; D008422:Materials Testing; D055595:Mechanical Phenomena; D015032:Zinc / Q000737:chemistry
D000497:Alloys; D001672:Biocompatible Materials; D008274:Magnesium; D015032:Zinc