Application of fatty acid and lipid measurements in neuropsychiatry.
The importance of lipids in the understanding of disease states is constantly increasing. Whilst the link between metabolic disorders and lipids seems to be clear, interpreting lipid regulation in the context of neuropsychiatric disorders is a new approach. Mental disorders account for almost 15% of the total global disease burden with Alzheimer's disease, depression or schizophrenia being amongst the most widespread mental disorders in the general population. For this reason rapid and early diagnosis is crucial and finding the right biomarkers is of great importance. Lipids appear to be essential in learning the aetiopathology of neuropsychiatric diseases as well as in biomarker research as they are most abundantly present in the brain. This study discusses recent findings in neuropsychiatry in the context of lipid analysis.
Agatha
A
Grela
Wojciech
W
Rachel
Michael
M
Cole
Tomasz
T
Zyss
Andrzej
A
Zięba
Wojciech
W
Piekoszewski
D001289:Attention Deficit Disorder with Hyperactivity / Q000097:blood / Q000175:diagnosis / Q000378:metabolism; D015415:Biomarkers / Q000032:analysis* / Q000097:blood; D001921:Brain / Q000378:metabolism; D042241:Early Diagnosis; D005227:Fatty Acids / Q000032:analysis* / Q000097:blood; D015525:Fatty Acids, Omega-3 / Q000032:analysis / Q000097:blood; D043371:Fatty Acids, Omega-6 / Q000032:analysis / Q000097:blood; D006801:Humans; D008055:Lipids / Q000032:analysis* / Q000097:blood; D001523:Mental Disorders / Q000097:blood / Q000175:diagnosis* / Q000378:metabolism
D015415:Biomarkers; D005227:Fatty Acids; D015525:Fatty Acids, Omega-3; D043371:Fatty Acids, Omega-6; D008055:Lipids