Xanthones from the herb of Swertia elata and their anti-TMV activity.
Two new xanthones (1-2), together with four known ones (3-6), were isolated from whole herb of Swertia elata. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Their anti-tobacco mosaic virus (anti-TMV) activity test revealed that 1-6 showed weak anti-TMV activities with inhibition rate in the range of 15.2-28.8% at the concentration of 20 μM.
a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
Wei
W
Jiang
b Technology Center , China Tobacco Yunnan Industry Company (Ltd.) , Kunming , P.R. China.
Dong-Lai
DL
Zhu
b Technology Center , China Tobacco Yunnan Industry Company (Ltd.) , Kunming , P.R. China.
Ming-Feng
MF
Wang
a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
Qing-Song
QS
Yang
a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
Ma-Yi
MY
Zuo
a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
Liang
L
Zeng
a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
Gan-Peng
GP
Li
D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D029967:Swertia / Q000737:chemistry*; D014027:Tobacco Mosaic Virus / Q000187:drug effects*; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000998:Antiviral Agents; D044004:Xanthones
Swertia elata; anti-TMV activity; xanthones