Utilization of organs from donors after circulatory death for vascularized pancreas and islet of Langerhans transplantation: recommendations from an expert group.
Donation after circulatory death (DCD) donors are increasingly being used as a source of pancreas allografts for vascularized organ and islet transplantation. We provide practice guidelines aiming to increase DCD pancreas utilization. We review risk assessment and donor selection criteria. We report suggested factors in donor and recipient clinical management and provide an overview of the activities and outcomes of vascularized pancreas and islet transplantation.
Department of Surgery, University of Geneva Hospitals, Geneva, Switzerland.
Thierry
T
Berney
Nuffield Department of Surgery, Oxford Transplant Centre, University of Oxford, Oxford, UK.
Catherine
C
Boffa
Department of Transplantation, Central Manchester University Hospitals, Manchester, UK.
Titus
T
Augustine
Division of Urology and Transplant Surgery, Hospices Civils de Lyon, Lyons, France.
Lionel
L
Badet
Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.
Eelco
E
de Koning
Department of General, Visceral and Transplant Surgery, Charité-University Hospital, Berlin, Germany.
Johann
J
Pratschke
Department of Surgery, Scientific Institute San Raffaele, Milan, Italy.
Carlo
C
Socci
Nuffield Department of Surgery, Oxford Transplant Centre, University of Oxford, Oxford, UK.
Peter
P
Friend
D064591:Allografts; D001926:Brain Death; D003643:Death; D046148:Donor Selection; D005260:Female; D006085:Graft Survival; D006801:Humans; D007515:Islets of Langerhans / Q000098:blood supply*; D016381:Islets of Langerhans Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009926:Organ Preservation; D016377:Organ Transplantation / Q000379:methods*; D010179:Pancreas / Q000098:blood supply*; D011184:Postoperative Period; D018570:Risk Assessment; D014019:Tissue Donors; D009927:Tissue and Organ Procurement
donation after cardiac death; donation after circulatory death; guidelines; islet of Langerhans; non-heart beating donation; pancreas; review