Chronic occupational N, N-dimethylformamide poisoning induced death: a case report.
N, N-dimethylformamide (DMF) is a toxic solvent that is widely used in many industries. Death directly attributed to DMF poisoning is rare. We report the case of a 40-year-old female who died of liver failure after occupational exposure to DMF poisoning over the course of 70 days, followed by 64 days treatment in hospital. Based on clinical procedures, autopsy findings, and environmental air quality assessment, the death in this case was confirmed to be the result of chronic DMF poisoning. This case gives further insight into occupational chronic poisoning-induced death, especially with negative toxicological analysis of rapid metabolism toxins poisoning.
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, NO. 13 Hangkong Road, Wuhan, 430030, People's Republic of China. zhanghui8506@gmail.com.
Hui
H
Zhang
Department of Investigation, Hubei University of Police, Wuhan, 430030, People's Republic of China. hbjg_lq501@126.com.
Quan
Q
Liu
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, NO. 13 Hangkong Road, Wuhan, 430030, People's Republic of China. gerichtsarzt@hotmail.com.
Yijie
Y
Duan
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, NO. 13 Hangkong Road, Wuhan, 430030, People's Republic of China. hongmeidong1@hotmail.com.
Hongmei
H
Dong
Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, NO. 13 Hangkong Road, Wuhan, 430030, People's Republic of China. zhouyiwu1@gmail.com.
Yiwu
Y
Zhou
D000328:Adult; D001284:Atrophy / Q000473:pathology; D004126:Dimethylformamide / Q000506:poisoning*; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D017093:Liver Failure / Q000139:chemically induced*; D016273:Occupational Exposure / Q000009:adverse effects*; D012997:Solvents / Q000506:poisoning*
D012997:Solvents; D004126:Dimethylformamide
Forensic pathology; Forensic toxicology; N, N-dimethylformamide (DMF); Negative toxicological analysis; Occupational disease