Aneuploidy: Tolerating Tolerance.
Individuals, and cells, vary in their ability to tolerate aneuploidy, an unbalanced chromosome complement. Tolerance mechanisms can be karyotype-specific or general. General tolerance mechanisms may allow cells to benefit from the phenotypic plasticity conferred by access to multiple aneuploid states.
Pacific Northwest Diabetes Research Institute, Seattle, WA 98122, USA.
Gareth A
GA
Cromie
Pacific Northwest Diabetes Research Institute, Seattle, WA 98122, USA. Electronic address: aimee.dudley@gmail.com.
Aimée M
AM
Dudley
D000782:Aneuploidy; D004303:Dosage Compensation, Genetic; D018628:Gene Dosage; D005800:Genes, Fungal; D008957:Models, Genetic; D012441:Saccharomyces cerevisiae / Q000235:genetics*