Nanoporous Metal-Phenolic Particles as Ultrasound Imaging Probes for Hydrogen Peroxide.
Nanoporous metal-phenolic particles are fabricated through the nanostructural replication of dense FeIII-TA complexes in nanoporous CaCO3template particles. The particles have potential for the diagnostic detection of endogenous levels of H2O2ex vivo and in vivo by ultrasound imaging, which is based on the catalytic activity of the coordinated Fe3+in the particles to break down H2O2to O2microbubbles.
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, 3010, Australia.
Junling
J
Guo
Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia.|Central Clinical School, Monash University, Melbourne, Victoria, 3004, Australia.
Xiaowei
X
Wang
Cellular and Molecular Metabolism, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia.
Darren C
DC
Henstridge
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, 3010, Australia.
Joseph J
JJ
Richardson
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, 3010, Australia.
Jiwei
J
Cui
Oxidative Stress, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia.
Arpeeta
A
Sharma
Cellular and Molecular Metabolism, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia.
Mark A
MA
Febbraio
Atherothrombosis and Vascular Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia.|Central Clinical School, Monash University, Melbourne, Victoria, 3004, Australia.|School of Applied Sciences, RMIT University, Melbourne, Victoria, 3000, Australia.
Karlheinz
K
Peter
Oxidative Stress, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia.
Judy B
JB
de Haan
Central Clinical School, Monash University, Melbourne, Victoria, 3004, Australia.|School of Applied Sciences, RMIT University, Melbourne, Victoria, 3000, Australia.|Vascular Biotechnology, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, 3004, Australia.
Christoph E
CE
Hagemeyer
ARC Centre of Excellence in Convergent Bio-Nano Science and Technology and the Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, 3010, Australia.
Frank
F
Caruso
hydrogen peroxide; metal-phenolic particles; ultrasound imaging