Non-Medical Prescription Opioid Use and Prescription Opioid Use Disorder: A Review.
Over the past few decades, there has been a rise in the non-medical use of prescription opioids, which has now reached epidemic proportions in the United States. In some cases, this non-medical use progresses to prescription opioid use disorder, heroin use, injection, and inhalation drug use, all of which may have further devastating consequences. The purpose of this review article is to discuss the epidemiology of the non-medical use of prescription opioids; discuss the potential progression to subsequent prescription opioid use disorder; review the state and national efforts in development to address addiction and diversion in the United States; discuss treatment options; and, lastly, to evaluate the impact of the related stigma to the development of opioid use disorder. Many unanswered questions remain, and we will explore future possibilities in how the medical community can play a role in curbing this epidemic.
Internal Medicine, Addiction Medicine, Yale University, New Haven, Connecticut.
Jeanette M
JM
Tetrault
Internal Medicine, Addiction Medicine, Yale University, New Haven, Connecticut.
Jenna L
JL
Butner
D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D019317:Evidence-Based Medicine; D006801:Humans; D015994:Incidence; D009292:Narcotic Antagonists / Q000627:therapeutic use; D058850:Opiate Substitution Treatment / Q000706:statistics & numerical data*; D009293:Opioid-Related Disorders / Q000453:epidemiology* / Q000517:prevention & control*; D063487:Prescription Drug Misuse / Q000517:prevention & control* / Q000706:statistics & numerical data*; D012307:Risk Factors; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
D009292:Narcotic Antagonists
opioid agonist treatment; opioid use disorder; prescription opioid use disorder; substance use disorder