Oxygen--a limiting factor for brain recovery.
Effective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain (e.g., intracerebral hemorrhage), a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Conversely, increasing brain oxygenation, by the use of hyperbaric oxygen therapy, can improve brain metabolism and its dependent regenerative processes.
Sagol Center for Hyperbaric Medicine and Research, Assaf Harofeh Medical Center, Zerifin, 70300, Israel.|Sackler School of Medicine, Tel-Aviv University, Klachkin 25, Tel Aviv, 69978, Israel.
Amir
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Hadanny
Sagol Center for Hyperbaric Medicine and Research, Assaf Harofeh Medical Center, Zerifin, 70300, Israel. efratishai@013.net.|Sackler School of Medicine, Tel-Aviv University, Klachkin 25, Tel Aviv, 69978, Israel. efratishai@013.net.|Research and Development Unit, Assaf Harofeh Medical Center, Zerifin, 70300, Israel. efratishai@013.net.|Sagol School of Neuroscience, Tel-Aviv University, Klachkin 25, Tel Aviv, 69978, Israel. efratishai@013.net.
Shai
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Efrati
D000531:Altitude; D000818:Animals; D002543:Cerebral Hemorrhage / Q000628:therapy*; D006931:Hyperbaric Oxygenation