Molecular characterization of novel reassortant H6N2 subtype avian influenza viruses isolated from poultry in Eastern China, in 2014.
During the surveillance for avian influenza viruses (AIVs) in live poultry markets in Eastern China, in 2014, seven H6N2 AIVs were isolated from poultry. Phylogenetic analysis showed that these strains received their genes from H6, H3, and H9 AIVs of poultry in China. These strains were found to demonstrate moderate pathogenicity in mice, and were able to replicate in mice without prior adaptation. Considering that novel reassorted H6N2 viruses were isolated from poultry in this study, it is possible that these chickens and ducks play an important role in the generation of novel reassorted H6N2 AIVs.
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, 310003 Hangzhou, China. Electronic address: wuhaibo2014@163.com.
Haibo
H
Wu
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, 310003 Hangzhou, China.
Xiuming
X
Peng
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, 310003 Hangzhou, China.
Xiaorong
X
Peng
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, 310003 Hangzhou, China.
Linfang
L
Cheng
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, 310003 Hangzhou, China. Electronic address: flwnp2013@163.com.
Nanping
N
Wu
D000818:Animals; D002681:China / Q000453:epidemiology; D005838:Genotype; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000235:genetics; D009980:Influenza A virus / Q000145:classification* / Q000235:genetics*; D005585:Influenza in Birds / Q000453:epidemiology / Q000821:virology*; D009439:Neuraminidase / Q000235:genetics; D010802:Phylogeny; D011200:Poultry / Q000821:virology*; D016865:Reassortant Viruses; D014764:Viral Proteins / Q000235:genetics
D019267:Hemagglutinin Glycoproteins, Influenza Virus; D014764:Viral Proteins; C487630:NA protein, influenza A virus; D009439:Neuraminidase
Avian influenza viruses; Poultry; Reassortment; Subtype H6N2