A cascade of protein aggregation bombards mitochondria for neurodegeneration and apoptosis under WWOX deficiency.
Department of Cell Biology and Anatomy, National Cheng Kung University, Tainan, Taiwan, ROC.
C I
CI
Sze
Department of Cell Biology and Anatomy, National Cheng Kung University, Tainan, Taiwan, ROC.
Y M
YM
Kuo
Department of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Tainan, Taiwan, ROC.
L J
LJ
Hsu
Department of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Tainan, Taiwan, ROC.
T F
TF
Fu
Department of Neurosurgery, MacKay Memorial Hospital Taipei, and Graduate Institute of Injury Prevention and Control, Taipei Medical University, Taipei, Taiwan, ROC.
M F
MF
Chiang
Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.
J Y
JY
Chang
Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.|Advanced Optoelectronic Technology Center, National Cheng Kung University, Tainan, Taiwan, ROC.|Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
N S
NS
Chang
D000818:Animals; D017209:Apoptosis; D006801:Humans; D051379:Mice; D008928:Mitochondria / Q000378:metabolism*; D019636:Neurodegenerative Diseases / Q000235:genetics* / Q000378:metabolism*; D010088:Oxidoreductases / Q000235:genetics* / Q000378:metabolism*; D066329:Protein Aggregates; D025521:Tumor Suppressor Proteins / Q000235:genetics* / Q000378:metabolism*; D000074584:WW Domain-Containing Oxidoreductase
D066329:Protein Aggregates; D025521:Tumor Suppressor Proteins; D010088:Oxidoreductases; D000074584:WW Domain-Containing Oxidoreductase; C486071:WWOX protein, human