A Method that Will Captivate U.
In an age of next-generation sequencing, the ability to purify RNA transcripts has become a critical issue. In this issue, Duffy et al. (2015) improve on a pre-existing technique of RNA labeling and purification by 4-thiouridine tagging. By increasing the efficiency of RNA capture, this method will enhance the ability to study RNA dynamics, especially for transcripts normally inefficiently captured by previous methods.
Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, OH 44106, USA.
Sophie
S
Martin
Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address: jmc71@case.edu.
Jeff
J
Coller
D006801:Humans; D035683:MicroRNAs / Q000737:chemistry*
D035683:MicroRNAs