Cell and in vivo imaging of fluoride ion with highly selective bioluminescent probes.
Two rapid bioluminescent probes for the detection of fluoride ion were developed on the basis of F-Si bond formation herein. It should be noted that probe 1 exhibited highly selective and sensitive detection toward fluoride ion over other anions and has been successfully applied in imaging fluoride ion in both living cells and animals.
Department of Anaesthesiology and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China.
Bowen
B
Ke
Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmacy, Shandong University , Jinan, Shandong 250012, China.
Wenxiao
W
Wu
Department of Anaesthesiology and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China.
Liu
L
Wei
Department of Anaesthesiology and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China.
Fengbo
F
Wu
Department of Anaesthesiology and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China.
Guo
G
Chen
Department of Anaesthesiology and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China.
Gu
G
He
Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmacy, Shandong University , Jinan, Shandong 250012, China.
Minyong
M
Li
D000818:Animals; D002460:Cell Line; D002470:Cell Survival; D005459:Fluorides / Q000032:analysis* / Q000737:chemistry*; D049408:Luminescent Agents / Q000737:chemistry*; D051379:Mice; D057054:Molecular Imaging / Q000379:methods*; D012825:Silicon / Q000737:chemistry
D049408:Luminescent Agents; D005459:Fluorides; D012825:Silicon