Treatment of Alopecia Areata in the United States: A Retrospective Cross-Sectional Study.
BACKGROUND
Alopecia Areata (AA) is a non-scarring alopecia that affects millions of Americans, however the way it is treated and which patients seek treatment is not well characterized.


OBJECTIVE
To better understand how AA was being treated in the United States, what type of patients are seen for AA, and what physicians treated them.


METHODS
We analyzed data from the National Ambulatory Medical Care Survey (NAMCS) and National Hospital Ambulatory Medical Care Survey (NHAMCS) from 2001 to 2010. We tabulated patient characteristics, the physicians who treated AA and what treatments were prescribed for AA.


RESULTS
There were an estimated 2.6 million outpatient visits for AA. Patients with AA were most commonly treated by a dermatologists (84.8%). Patients were most commonly treated with topical and injected corticosteroids (61.0%) followed by minoxidil (5.9%) and topical tacrolimus (5.7%). Males made fewer visits per 1,000 capita compared to females (P=0.01).


CONCLUSIONS
The NAMCS and NHAMCS do not record severity of disease data.


CONCLUSIONS
Topical and injected corticosteroids are the mainstay of treatment for AA, however the use of steroid sparing agents such as minoxidil is low. Despite no studies demonstrating efficacy, topical tacrolimus was used almost as frequently as minoxidil.
Michael E
ME
Farhangian
Amy J
AJ
McMichael
Karen E
KE
Huang
Steven R
SR
Feldman
D000279:Administration, Cutaneous; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data; D000506:Alopecia Areata / Q000188:drug therapy*; D065095:Calcineurin Inhibitors / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D003880:Dermatology / Q000706:statistics & numerical data*; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D007267:Injections; D008297:Male; D008914:Minoxidil / Q000627:therapeutic use; D009819:Office Visits / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012737:Sex Factors; D016559:Tacrolimus / Q000627:therapeutic use; D014481:United States; D014665:Vasodilator Agents / Q000627:therapeutic use; D044465:White People / Q000706:statistics & numerical data
D000305:Adrenal Cortex Hormones; D065095:Calcineurin Inhibitors; D014665:Vasodilator Agents; D008914:Minoxidil; D016559:Tacrolimus