Mycobacterium tuberculosis complex transmission is not associated with recent immigration (≤5 years) in Florida.
As tuberculosis (TB) incidence decreases in the US, foreign-born persons continue to account for a larger proportion of the burden. In these cross-sectional analyses of 1149 culture-confirmed TB cases genotyped using spoligotyping and 24-locus MIRU, we show that over a quarter of cases among the foreign-born population in Florida resulted from recent transmission of the Mycobacterium tuberculosis complex. In addition, over a third of these cases occurred among persons who had immigrated 5 years or less prior to their diagnosis. Although recent immigration was not a significant predictor of TB transmission, younger age, birthplace in the Americas, homelessness, drug use and TB lineage are risk factors for TB transmission among the foreign-born population in Florida. These data provide actionable insights into TB transmission among the foreign-born population in Florida.
Southern National Tuberculosis Center, Division of Infectious Diseases and Global Medicine, University of Florida College of Medicine, 2055 Mowry Road, P.O. Box 103600, Gainesville, FL 32610, USA. Electronic address: nseraphin@ufl.edu.
Marie Nancy
MN
Séraphin
Southern National Tuberculosis Center, Division of Infectious Diseases and Global Medicine, University of Florida College of Medicine, 2055 Mowry Road, P.O. Box 103600, Gainesville, FL 32610, USA. Electronic address: Mike.Lauzardo@medicine.ufl.edu.
Michael
M
Lauzardo
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004641:Emigration and Immigration; D005260:Female; D005431:Florida / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000235:genetics; D016017:Odds Ratio; D012307:Risk Factors; D014376:Tuberculosis / Q000453:epidemiology* / Q000635:transmission*; D055815:Young Adult
Foreign-born populations; Transmission; Tuberculosis; United States