Copper-mediated stereospecific C-H oxidative sulfenylation of terminal alkenes with disulfides.
A copper and iodine-mediated C-H oxidative sulfenylation of olefins with diaryl disulfides has been developed for the stereospecific synthesis of vinyl thioether. With the combination of Cu(OTf)2 and I2, a variety of terminal alkenes underwent oxidative coupling reaction with various diaryl disulfides successfully to afford the corresponding E-vinyl sulfides in moderate to good yields.
College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China. zxg@wzu.edu.cn.
Hai-Yong
HY
Tu
Bo-Lun
BL
Hu
Chen-Liang
CL
Deng
Xing-Guo
XG
Zhang
D000475:Alkenes / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry*
D000475:Alkenes; D013440:Sulfides; D003300:Copper; D007455:Iodine