[Effects of Vitamin B12 in Patients with Amyotrophic Lateral Sclerosis and Peripheral Neuropathy].
Vitamin B(12)(vB(12)) deficient is regarded as iatrogenic in some cases. Although the recommended oral intake of vB(12) has been determined, administration of vB(12) exceeding the recommended dose could have multiple pharmacological effects. "Ultra-high dose" vB(12) therapy has been used for peripheral neuropathy and amyotrophic lateral sclerosis, suggesting its promising neuroprotective effects.
Department of Neurology, Tokushima University Hospital.
Hiroyuki
H
Nodera
Yuishin
Y
Izumi
Ryuji
R
Kaji
D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy*; D006801:Humans; D019636:Neurodegenerative Diseases / Q000188:drug therapy; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D010523:Peripheral Nervous System Diseases / Q000188:drug therapy*; D016896:Treatment Outcome; D014805:Vitamin B 12 / Q000627:therapeutic use*
D018696:Neuroprotective Agents; D014805:Vitamin B 12