IL-1 as a target in inflammation.
Inflammation is a protective response to eliminate cytotoxic agents and pathogens. Various factors are thought to be involved in the pathological changes in tissues caused by inflammation. Interleukin 1, an inflammatory cytokine, is thought to have diverse physiological functions and to play an important role in inflammatory disease. In this review, we discuss interleukin-1 as a target of inflammatory disease.
Yuki
Y
Ito
Naoe
N
Kaneko
Tomoyuki
T
Iwasaki
Shinnosuke
S
Morikawa
Kentaro
K
Kaneko
Department of Pathology Ehime University Proteo-Science Centre and Graduate School of Medicine Shitsukawa 454, Toon, Ehime 791-0295, Japan. masumoto@m.ehime-u.ac.jp.
Junya
J
Masumoto
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000378:metabolism; D018836:Inflammation Mediators / Q000037:antagonists & inhibitors / Q000378:metabolism*; D007375:Interleukin-1 / Q000037:antagonists & inhibitors / Q000378:metabolism*
D000893:Anti-Inflammatory Agents; D018836:Inflammation Mediators; D007375:Interleukin-1