Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial.
Protein supplementation in combination with resistance training may increase muscle mass and muscle strength in elderly subjects. The objective of this study was to assess the influence of post-exercise protein supplementation with collagen peptides v. placebo on muscle mass and muscle function following resistance training in elderly subjects with sarcopenia. A total of fifty-three male subjects (72·2 (sd 4·68) years) with sarcopenia (class I or II) completed this randomised double-blind placebo-controlled study. All the participants underwent a 12-week guided resistance training programme (three sessions per week) and were supplemented with either collagen peptides (treatment group (TG)) (15 g/d) or silica as placebo (placebo group (PG)). Fat-free mass (FFM), fat mass (FM) and bone mass (BM) were measured before and after the intervention using dual-energy X-ray absorptiometry. Isokinetic quadriceps strength (IQS) of the right leg was determined and sensory motor control (SMC) was investigated by a standardised one-leg stabilisation test. Following the training programme, all the subjects showed significantly higher (P<0·01) levels for FFM, BM, IQS and SMC with significantly lower (P<0·01) levels for FM. The effect was significantly more pronounced in subjects receiving collagen peptides: FFM (TG +4·2 (sd 2·31) kg/PG +2·9 (sd 1·84) kg; P<0·05); IQS (TG +16·5 (sd 12·9) Nm/PG +7·3 (sd 13·2) Nm; P<0·05); and FM (TG -5·4 (sd 3·17) kg/PG -3·5 (sd 2·16) kg; P<0·05). Our data demonstrate that compared with placebo, collagen peptide supplementation in combination with resistance training further improved body composition by increasing FFM, muscle strength and the loss in FM.
1Department for Nutrition,Institute for Sports and Sports Science,University of Freiburg,Freiburg 79117,Germany.
Denise
D
Zdzieblik
2CRI,Collagen Research Institute GmbH,Kiel 24118,Germany.
Steffen
S
Oesser
3Department of Rehabilitation,Prevention and Sports Medicine,Centre for Internal Medicine,University Hospital Freiburg,79106 Freiburg,Germany.
Manfred W
MW
Baumstark
1Department for Nutrition,Institute for Sports and Sports Science,University of Freiburg,Freiburg 79117,Germany.
Albert
A
Gollhofer
1Department for Nutrition,Institute for Sports and Sports Science,University of Freiburg,Freiburg 79117,Germany.
Daniel
D
König
D015502:Absorptiometry, Photon; D000368:Aged; D001823:Body Composition / Q000187:drug effects*; D015519:Bone Density / Q000187:drug effects; D003094:Collagen / Q000008:administration & dosage*; D019587:Dietary Supplements; D004311:Double-Blind Method; D002149:Energy Intake; D006801:Humans; D008297:Male; D053580:Muscle Strength / Q000187:drug effects*; D018482:Muscle, Skeletal / Q000187:drug effects / Q000502:physiology; D052097:Quadriceps Muscle / Q000187:drug effects / Q000502:physiology; D055070:Resistance Training; D055948:Sarcopenia / Q000188:drug therapy*
D003094:Collagen
Ageing; Collagen hydrolysate; Collagen peptides; FFM fat-free mass; FM fat mass; PG placebo group; Protein supplementation; RCT randomised controlled trial; Resistance exercise; Sarcopenia; TG treatment group