Restless Legs Syndrome and Psychiatric Disorders.
There are strong epidemiologic ties between restless legs syndrome (RLS) and a wide array of psychiatric conditions. Although the mechanism of this association is not fully understood, there are likely bidirectional cause-and-effect relationships. Appreciation of psychiatric comorbidity is an essential component of the treatment of RLS. Clinicians should be prepared to facilitate appropriate psychiatric treatment and consider the complex interactions between psychiatric medications, RLS medications, and the clinical course of both illnesses.
Department of Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: semackie@partners.org.
Susan
S
Mackie
Sleep Disorders Clinical Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 1 Bowdoin Square, 9th floor, Boston, MA 02114, USA; Sleep Disorders Clinical Research Program, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, 1 Bowdoin Square, 9th floor, Boston, MA 02114, USA.
John W
JW
Winkelman
D015897:Comorbidity; D006801:Humans; D001523:Mental Disorders / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D012148:Restless Legs Syndrome / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology
Antidepressants; Depression; Epidemiology; Psychiatric disorders; Psychopharmacology; Restless legs syndrome