18F-FDG PET/CT Prediction of an Aggressive Clinical Course for Dermatofibrosarcoma Protuberans.
The ability to assess tumor biology is a benefit of molecular imaging with (18)F-FDG PET/CT, which performs better than anatomic imaging in evaluating malignancies. We present an unusual case of fatal dermatofibrosarcoma protuberans, a usually indolent entity for which high-grade (18)F-FDG uptake was predictive of an aggressive clinical course unabated by tyrosine kinase inhibitor imatinib mesylate, to which the patient showed a poor response.
Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Hospital Annexe, Mumbai, India; and drsanb@yahoo.com.
Sandip
S
Basu
Solapur Cancer Center, Solapur, India.
Fahim
F
Goliwale
D018223:Dermatofibrosarcoma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D000072078:Positron Emission Tomography Computed Tomography; D016896:Treatment Outcome
D019788:Fluorodeoxyglucose F18
FDG PET-CT; dermatofibrosarcoma protuberans; tumor biology