Primary Hyperparathyroidism with Extensive Brown Tumors and Multiple Fractures in a 20-Year-Old Woman.
A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of primary hyperparathyroidism, they are rarely seen in clinical practice. In this report, we present a case of 20-year-old woman with recurrent fractures and bone pain. Plain digital radiographs of the affected bones revealed multiple erosive bone tumors, which were finally diagnosed as brown tumors associated with primary hyperparathyroidism due to a parathyroid adenoma. This case shows that multiple, and clinically severe form of brown tumors can even occur in young patients.
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Ju Hee
JH
Choi
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Kyoung Jin
KJ
Kim
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Ye Jin
YJ
Lee
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Sun Hwa
SH
Kim
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Sin Gon
SG
Kim
Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
Kwang Yoon
KY
Jung
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Dong Seop
DS
Choi
Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. pourlife@naver.com.
Nam Hoon
NH
Kim
Brown tumor; Hyperparathyroidism; Parathyroid neoplasms