Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance.
BACKGROUND
Bipolar disorder is a highly heritable polygenic disorder. Recent enrichment analyses suggest that there may be true risk variants for bipolar disorder in the expression quantitative trait loci (eQTL) in the brain.


OBJECTIVE
We sought to assess the impact of eQTL variants on bipolar disorder risk by combining data from both bipolar disorder genome-wide association studies (GWAS) and brain eQTL.


METHODS
To detect single nucleotide polymorphisms (SNPs) that influence expression levels of genes associated with bipolar disorder, we jointly analysed data from a bipolar disorder GWAS (7481 cases and 9250 controls) and a genome-wide brain (cortical) eQTL (193 healthy controls) using a Bayesian statistical method, with independent follow-up replications. The identified risk SNP was then further tested for association with hippocampal volume (n = 5775) and cognitive performance (n = 342) among healthy individuals.


RESULTS
Integrative analysis revealed a significant association between a brain eQTL rs6088662 on chromosome 20q11.22 and bipolar disorder (log Bayes factor = 5.48; bipolar disorder P = 5.85 × 10(-5)). Follow-up studies across multiple independent samples confirmed the association of the risk SNP (rs6088662) with gene expression and bipolar disorder susceptibility (P = 3.54 × 10(-8)). Further exploratory analysis revealed that rs6088662 is also associated with hippocampal volume and cognitive performance in healthy individuals.


CONCLUSIONS
Our findings suggest that 20q11.22 is likely a risk region for bipolar disorder; they also highlight the informative value of integrating functional annotation of genetic variants for gene expression in advancing our understanding of the biological basis underlying complex disorders, such as bipolar disorder.
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Ming
M
Li
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Xiong-jian
XJ
Luo
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Mikael
M
Landén
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Sarah E
SE
Bergen
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Christina M
CM
Hultman
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Xiao
X
Li
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Wen
W
Zhang
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Yong-Gang
YG
Yao
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Chen
C
Zhang
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Jiewei
J
Liu
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Manuel
M
Mattheisen
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Sven
S
Cichon
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Thomas W
TW
Mühleisen
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Franziska A
FA
Degenhardt
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Markus M
MM
Nöthen
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Thomas G
TG
Schulze
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Maria
M
Grigoroiu-Serbanescu
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Hao
H
Li
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Chris K
CK
Fuller
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Chunhui
C
Chen
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Qi
Q
Dong
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Chuansheng
C
Chen
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Stéphane
S
Jamain
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Marion
M
Leboyer
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Frank
F
Bellivier
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Bruno
B
Etain
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Jean-Pierre
JP
Kahn
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Chantal
C
Henry
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Martin
M
Preisig
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Zoltán
Z
Kutalik
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Enrique
E
Castelao
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Adam
A
Wright
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Philip B
PB
Mitchell
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Janice M
JM
Fullerton
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Peter R
PR
Schofield
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Grant W
GW
Montgomery
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Sarah E
SE
Medland
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Scott D
SD
Gordon
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Nicholas G
NG
Martin
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Marcella
M
Rietschel
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Chunyu
C
Liu
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Joel E
JE
Kleinman
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Thomas M
TM
Hyde
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Daniel R
DR
Weinberger
Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi
Bing
B
Su
D000368:Aged; D001499:Bayes Theorem; D001714:Bipolar Disorder / Q000235:genetics*; D016022:Case-Control Studies; D002892:Chromosomes, Human, Pair 22; D003071:Cognition; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D016015:Logistic Models; D020641:Polymorphism, Single Nucleotide