Long-Term Exposure to High Altitude Affects Response Inhibition in the Conflict-monitoring Stage.
To investigate the effects of high-altitude exposure on response inhibition, event-related potential (ERP) components N2 and P3 were measured in Go/NoGo task. The participants included an 'immigrant' high-altitude group (who had lived at high altitude for three years but born at low altitude) and a low-altitude group (living in low altitude only). Although the behavioural data showed no significant differences between the two groups, a delayed latency of NoGo-N2 was found in the high-altitude group compared to the low-altitude group. Moreover, larger N2 and smaller P3 amplitudes were found in the high-altitude group compared to the low-altitude group, for both the Go and NoGo conditions. These findings suggest that high-altitude exposure affects response inhibition with regard to processing speed during the conflict monitoring stage. In addition, high altitude generally increases the neural activity in the matching step of information processing and attentional resources. These results may provide some insights into the neurocognitive basis of the effects on high-altitude exposure on response inhibition.
Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.|University of Chinese Academy of Sciences, Beijing, China.|Institute of Education and Psychology, Tibet University, Tibet, China.
Hailin
H
Ma
Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Yan
Y
Wang
Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Jianhui
J
Wu
Institute of Education and Psychology, Tibet University, Tibet, China.
Ping
P
Luo
Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Buxin
B
Han
D000531:Altitude; D001921:Brain / Q000000981:diagnostic imaging / Q000502:physiology; D003220:Conflict, Psychological; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010775:Photic Stimulation; D011859:Radiography; D011930:Reaction Time; D055815:Young Adult