[Management and prevention of adverse events in esthetic interventions].
BACKGROUND
Esthetic interventions are an integral part of today's dermatology. A plethora of novel agents and techniques is currently being launched on the market accompanied by a variety of side effects.


METHODS
We summarize the most common adverse events of fillers, laser treatments, and injection of botulinum toxin and present feasible means of prevention and management.


RESULTS
The profile of adverse events is more favorable in temporary fillers such as hyaluronic acid than in permanent ones. The most common filler-related adverse events include changes of skin color and unspecific swelling. Neural and vascular dysfunctions are observed less frequently, but may result in severe tissue necrosis or loss of vision. Undesirable events of laser treatments largely depend on the applied modality, localization, and indication. Local effects comprise erythema, swelling, crusting, blister formation, and weeping in extreme cases. The formation of laser-induced scarring is more likely to occur in lasers with high energies. Most adverse events of botulinum toxin are mild and transient. Pain and redness around the sites of injection are common. However, a poor injection technique and injection of too many units can trigger major motoric impairment with ptosis and dysarthria.


CONCLUSIONS
Excellent results can be achieved with esthetic interventions. To guarantee a maximum amount of safety and to minimize risks it is of paramount importance to work with clear indications and respect contraindications. It is important to recognize early adverse events to achieve satisfactory results and avoid severe complications.
Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland. Daniela.Hartmann@med.uni-muenchen.de.
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Hartmann
Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland.
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Heppt
Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland.
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Gauglitz
D019274:Botulinum Toxins, Type A / Q000009:adverse effects*; D002921:Cicatrix / Q000209:etiology / Q000517:prevention & control*; D003357:Cosmetic Techniques / Q000009:adverse effects; D000067548:Dermal Fillers / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000517:prevention & control*; D019317:Evidence-Based Medicine; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*
D000067548:Dermal Fillers; D019274:Botulinum Toxins, Type A
Botulinum toxin; Complications; Hyaluronic acid; Laser treatment; Prevention