MANAGEMENT OF ACUTE RENAL FAILURE WITH DELAYED HYPERCALCEMIA SECONDARY TO SARCOCYSTIS NEURONA-INDUCED MYOSITIS AND RHABDOMYOLYSIS IN A CALIFORNIA SEA LION (ZALOPHUS CALIFORNIANUS).
A 3-yr-old captive-born California sea lion (Zalophus californianus) developed Sarcocystis neurona-induced myositis and rhabdomyolysis that led to acute renal failure. The sea lion was successfully managed with fluid therapy, antiprotozoals, antibiotics, anti-inflammatories, antiemetics, gastroprotectants, and diuretics, but developed severe delayed hypercalcemia, a syndrome identified in humans after traumatic or exertion-induced rhabdomyolysis. Treatment with calcitonin was added to the management, and the individual recovered fully. The case emphasizes that animals with rhabdomyolysis-induced renal failure risk developing delayed hypercalcemia, which may be life threatening, and calcium levels should be closely monitored past the resolution of renal failure.
Amy B
AB
Alexander
Christopher S
CS
Hanley
Mary C
MC
Duncan
Kyle
K
Ulmer
Luis R
LR
Padilla
D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001835:Body Weight; D006934:Hypercalcemia / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D009220:Myositis / Q000150:complications / Q000469:parasitology / Q000662:veterinary*; D012206:Rhabdomyolysis / Q000150:complications / Q000469:parasitology / Q000662:veterinary; D012522:Sarcocystis / Q000145:classification*; D012523:Sarcocystosis / Q000150:complications / Q000188:drug therapy / Q000662:veterinary*; D046070:Sea Lions; D013997:Time Factors
D000890:Anti-Infective Agents
California sea lion; Sarcocystis neurona; Zalophus californianus; hypercalcemia; myositis; renal failure