One-pot synthesis of highly greenish-yellow fluorescent nitrogen-doped graphene quantum dots for pyrophosphate sensing via competitive coordination with Eu(3+) ions.
Highly fluorescent nitrogen-doped graphene quantum dots (N-GQDs) with greenish-yellow emission and quantum yield of 13.2% have been synthesized via a one-pot hydrothermal method. The obtained N-GQDs displayed excellent optical properties, high photostability and resistance to strong ion strength. Based on the higher affinity of pyrophosphate (PPi) than carboxyl and amido groups on the surface of the N-GQDs to Eu(3+), a Eu(3+)-modulated N-GQD off-on fluorescent probe for PPi detection was constructed with a detection limit of 0.074 μM. The detection process was simple in design, easy to operate, and showed a highly selective response to PPi in the presence of co-existing anions. This work widens the applications of N-GQDs with versatile functionality and reactivity in clinical diagnostics and as biosensors.
Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China. xichen@xmu.edu.cn.
Liping
L
Lin
Xinhong
X
Song
Yiying
Y
Chen
Mingcong
M
Rong
Tingting
T
Zhao
Yaqi
Y
Jiang
Yiru
Y
Wang
Xi
X
Chen
D015374:Biosensing Techniques; D002412:Cations / Q000737:chemistry; D011756:Diphosphates / Q000032:analysis* / Q000652:urine; D005063:Europium / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D009584:Nitrogen / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry*
D002412:Cations; D011756:Diphosphates; D005456:Fluorescent Dyes; D005063:Europium; C107241:diphosphoric acid; D006108:Graphite; D009584:Nitrogen