Optic Neuritis Associated with Myelodysplastic Syndrome Accompanied by Eosinophilic Crisis.
Myelodysplastic syndrome (MDS) was diagnosed in a 64-year-old man. Three months later, he presented with right-sided visual loss. A diagnosis of optic neuritis caused by both ischemic and non-ischemic changes was established. Concurrently, prominent eosinophilia was seen in both the peripheral blood and bone marrow. A partial improvement of visual loss was obtained concomitant with a rapid decrease of the eosinophils after treatment with corticosteroids. Optic neuritis related to MDS is a rare condition and its etiology has not yet been identified. We herein report a case of optic neuritis associated with MDS and accompanied by an eosinophilic crisis.
Hematology, Graduate School of Medicine, Osaka City University, Japan.
Joji
J
Nagasaki
Mitsutaka
M
Nishimoto
Hirohisa
H
Nakamae
Takahiko
T
Nakane
Hideo
H
Koh
Kumiko
K
Yoshimoto
Kunihiko
K
Shiraki
Masayuki
M
Hino
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D004802:Eosinophilia / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000473:pathology; D009902:Optic Neuritis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones