DNA Motif Databases and Their Uses.
Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications.
Washington University School of Medicine, St. Louis, Missouri.
Gary D
GD
Stormo
D001665:Binding Sites; D004247:DNA / Q000737:chemistry / Q000235:genetics*; D057225:Data Mining / Q000379:methods*; D030561:Databases, Nucleic Acid; D030562:Databases, Protein; D008969:Molecular Sequence Data; D059372:Nucleotide Motifs / Q000235:genetics*; D011485:Protein Binding; D017422:Sequence Analysis, DNA / Q000379:methods*; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics*
D014157:Transcription Factors; D004247:DNA
DNA motifs; binding site predictions; position weight matrices; transcription factors