Obese Smokers as a Potential Subpopulation of Risk in Tobacco Reduction Policy.
Smoking and obesity represent the largest challenges to public health. There is an established inverse relationship between body mass index (BMI) and smoking, but this relationship becomes more complicated among obese smokers. Smokers with higher BMI consume more cigarettes per day and may be more nicotine-dependent than lean smokers. Rates of obesity are lower among smokers than non-smokers, indicating that chronic exposure to tobacco smoke may prevent excess weight gain in people who would otherwise become obese. Furthermore, obese smokers may be more sensitive to the weight-suppressive and reinforcing effects of nicotine. Consequently, obese smokers may respond differently to reduction in the nicotine content of cigarettes, a tobacco control policy being considered both in the Unites States and abroad. Here, we review the interrelationship between nicotine and obesity in the context of a potential nicotine reduction policy. We discuss the implications of nicotine-induced body weight suppression in obese smokers, as well as the possibility that obesity might increase susceptibility to smoking and nicotine dependence.
Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania.
Laura E
LE
Rupprecht
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Eric C
EC
Donny
Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania ; Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Alan F
AF
Sved
D015897:Comorbidity; D006291:Health Policy; D006293:Health Promotion / Q000379:methods*; D006801:Humans; D009765:Obesity / Q000453:epidemiology* / Q000517:prevention & control; D015995:Prevalence; D018570:Risk Assessment; D012907:Smoking / Q000453:epidemiology*; D000074606:Smoking Prevention; D020340:Tobacco Use Cessation / Q000379:methods* / Q000706:statistics & numerical data*; D014481:United States / Q000453:epidemiology
insulin; nicotine; obesity; tobacco