The role of sentinel lymph nodes in endometrial and cervical cancer.
Sentinel lymph node assessment aims to determine lymphatic spread while preventing unnecessary interventions and morbidity for those who will not benefit from lymphadenectomy. All detection methods have demonstrated reasonable sensitivity with a low false negative rate and high negative predictive value; as long as the surgeon removes all enlarged lymph nodes and a site-specific lymphadenectomy is performed if there is no mapping. The significance of micrometastases and long term outcomes are yet to be determined.
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ohio State University, Columbus, Ohio.
Blair
B
Smith
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ohio State University, Columbus, Ohio.
Floor
F
Backes
D000465:Algorithms; D003124:Colorimetry / Q000379:methods; D004396:Coloring Agents; D016889:Endometrial Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*
D004396:Coloring Agents
cervical cancer; detection techniques; endometrial cancer; micrometastasis; sentinel lymph node; ultrastaging