A Modular Synthesis of Conformationally Preorganised Extended β-Strand Peptidomimetics.
Invited for the cover of this issue is the group of Andrew D. Hamilton and Sam Thompson at the University of Oxford (UK). The image depicts a new class of conformationally constrained β-strand mimetics mediating the interaction between two subunits of a protein that controls transcription. Read the full text of the article at 10.1002/chem.201501366.
Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA (UK).
Tohru
T
Yamashita
Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA (UK).
Peter C
PC
Knipe
Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA (UK).
Nathalie
N
Busschaert
Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA (UK). sam.thompson@chem.ox.ac.uk.
Sam
S
Thompson
Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA (UK). andrew.hamilton@chem.ox.ac.uk.
Andrew D
AD
Hamilton
D032701:Biomimetics; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D057786:Peptidomimetics / Q000138:chemical synthesis* / Q000737:chemistry; D017433:Protein Structure, Secondary; D014157:Transcription Factors / Q000737:chemistry*
D010455:Peptides; D057786:Peptidomimetics; D014157:Transcription Factors