Parry Romberg syndrome with a wide range of ocular manifestations: a case report.
BACKGROUND
Parry-Romberg syndrome (PRS) is a rare disorder characterized by unilateral facial atrophy affecting the skin, subcutaneous tissue, muscles, and sometimes extending to the osteocartilaginous structures. Ocular involvement is relatively rare.


METHODS
We present a case of a 23-year-old female caucasian patient with Parry Romberg syndrome and extensive ocular involvement: enophthalmos, uveitis, iris atrophy. Ultrasound biomicroscopy (UBM) demonstrated hypotrophy of the ciliary body. The ciliary body atrophy has been previously reported just once and can be an explanation for the hypotony, frequently present in these patients.


CONCLUSIONS
Parry Romberg syndrome is a rare multidisciplinary disease. Our case presents a full spectrum of ocular manifestations. The pathogenesis of hypotonia is discussed.
Department of Clinical Sciences, Ophthalmology Institute, University of Turin, Via Juvarra 19, 10100, Turin, Italy. antoniomfea@gmail.com.
Antonio Maria
AM
Fea
Department of Clinical Sciences, Ophthalmology Institute, University of Turin, Via Juvarra 19, 10100, Turin, Italy. vittoria.aragno@hotmail.it.
Vittoria
V
Aragno
Department of Clinical Sciences, Ophthalmology Institute, University of Turin, Via Juvarra 19, 10100, Turin, Italy. cristina.briamonte@gmail.com.
Cristina
C
Briamonte
Department of Clinical Sciences, Ophthalmology Institute, University of Turin, Via Juvarra 19, 10100, Turin, Italy. maurofranzone@virgilio.it.
Mauro
M
Franzone
Department of Clinical Sciences, Ophthalmology Institute, University of Turin, Via Juvarra 19, 10100, Turin, Italy. edivado461@gmail.com.
Davide
D
Putignano
Department of Clinical Sciences, Ophthalmology Institute, University of Turin, Via Juvarra 19, 10100, Turin, Italy. federico.grignolo@unito.it.
Federico Maria
FM
Grignolo
D001284:Atrophy / Q000000981:diagnostic imaging; D002924:Ciliary Body / Q000000981:diagnostic imaging / Q000473:pathology*; D015841:Enophthalmos / Q000175:diagnosis*; D005150:Facial Hemiatrophy / Q000175:diagnosis*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007498:Iris / Q000000981:diagnostic imaging / Q000473:pathology*; D033401:Microscopy, Acoustic; D014057:Tomography, X-Ray Computed; D014605:Uveitis / Q000175:diagnosis*; D055815:Young Adult