Correlates of PrEP Indication in a Multi-Site Cohort of Young HIV-Uninfected Transgender Women.
Transgender women are at high risk of HIV infection, with younger transgender women (YTW) particularly vulnerable. Pre-Exposure Prophylaxis (PrEP) has shown efficacy in reducing HIV acquisition, but little is known about PrEP indication or initiation among YTW. Baseline data from 180 YTW age 18-29 years enrolled in Project LifeSkills, an on-going HIV prevention intervention for YTW, were analyzed to examine factors associated with PrEP indication. The sample (mean age = 23.4, SD = 3.2) was comprised largely of women of color (69 %) and of low socioeconomic status (71 % unemployed). Overall, 62 % met criteria for PrEP indication, but only 5 % reported ever taking PrEP. Factors associated with increased odds of PrEP indication were: PrEP interest (aOR 3.24; 95 % CI 1.44, 7.33), number of recent anal sex partners (aOR 1.23; 95 % CI 1.04, 1.46), and lower collective self-esteem scores (aOR 0.67; 95 % CI 0.47, 0.94). Despite high levels of PrEP indication, there remain low levels of PrEP awareness and uptake among YTW.
Division of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital, 225 E. Chicago Avenue, Box 161, Chicago, IL, 60611, USA. lkuhns@luriechildrens.org.|Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. lkuhns@luriechildrens.org.
Lisa M
LM
Kuhns
The Fenway Institute, Fenway Health, Boston, MA, USA.|Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
Sari L
SL
Reisner
The Fenway Institute, Fenway Health, Boston, MA, USA.|Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.|Department of Psychiatry, Harvard Medical School/Massachusetts General Hospital, Boston, MA, USA.
Matthew J
MJ
Mimiaga
Division of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital, 225 E. Chicago Avenue, Box 161, Chicago, IL, 60611, USA.|Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Travis
T
Gayles
Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Michael
M
Shelendich
Division of Adolescent Medicine, Ann & Robert H. Lurie Children's Hospital, 225 E. Chicago Avenue, Box 161, Chicago, IL, 60611, USA.|Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Robert
R
Garofalo
D000293:Adolescent; D019380:Anti-HIV Agents / Q000008:administration & dosage*; D001900:Boston; D002641:Chicago; D055812:Community-Based Participatory Research; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D018023:HIV Seronegativity; D007722:Health Knowledge, Attitudes, Practice; D006297:Health Services Accessibility; D006801:Humans; D008297:Male; D065129:Pre-Exposure Prophylaxis; D012649:Self Concept; D012747:Sexual Partners; D012944:Social Support; D012959:Socioeconomic Factors; D063106:Transgender Persons; D055815:Young Adult
D019380:Anti-HIV Agents
HIV; PrEP; Transgender; Young adults