Controlled trial comparing the efficacy of 88% phenol versus 10% sodium hydroxide for chemical matricectomy in the management of ingrown toenail.
BACKGROUND
Partial nail avulsion with lateral chemical matricectomy is the treatment of choice for ingrown toenails. Phenol (88%) is the most widely used chemical agent but prolonged postoperative drainage and collateral damage are common. Sodium hydroxide (NaOH) 10% has fewer side-effects.


METHODS
Adult, consenting patients with ingrown toenails were alternately allocated into two treatment groups in the order of their joining the study, to receive either 88% phenol (Group 1, n = 26) or 10% NaOH (Group 0, n = 23) chemical matricectomy. The patients as well as the statistician were blinded to the agent being used. Post-procedure follow-up evaluated median duration of pain, discharge, and healing along with recurrence, if any, in both the groups. The group wise data was statistically analyzed.


RESULTS
Both the groups responded well to treatment with the median duration of postoperative pain being 7.92 days in Group 0 and 16.25 days in Group 1 (P < 0.202). Postoperative discharge continued for a median period of 15.42 days (Group 0) and 18.13 days (Group 1) (P < 0.203). The tissue condition normalized in 7.50 days (Group 0) and 15.63 days (Group 1) (P < 0.007).


CONCLUSIONS
Limited postsurgical follow up of 6 months is a limitation of the study.


CONCLUSIONS
Chemical matricectomy using NaOH is as efficacious as phenolisation, with the advantage of faster tissue normalization.
Department of Dermatology and STD, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, Delhi, India.
Chander
C
Grover
Ananta
A
Khurana
Sambit Nath
SN
Bhattacharya
Arun
A
Sharma
D000328:Adult; D019468:Disease Management; D004322:Drainage / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009263:Nails, Ingrown / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D010147:Pain Measurement / Q000187:drug effects / Q000379:methods; D019800:Phenol / Q000008:administration & dosage*; D012972:Sodium Hydroxide / Q000008:administration & dosage*; D016896:Treatment Outcome; D055815:Young Adult
D019800:Phenol; D012972:Sodium Hydroxide