Smoking and interstitial lung diseases.
For many years has been well known that smoking could cause lung damage. Chronic obstructive pulmonary disease and lung cancer have been the two most common smoking-related lung diseases. In the recent years, attention has also focused on the role of smoking in the development of interstitial lung diseases (ILDs). Indeed, there are three diseases, namely respiratory bronchiolitis-associated ILD, desquamative interstitial pneumonia and pulmonary Langerhans cell histiocytosis, that are currently considered aetiologically linked to smoking and a few others which are more likely to develop in smokers. Here, we aim to focus on the most recent findings regarding the role of smoking in the pathogenesis and clinical behaviour of ILDs.
Interstitial Lung Disease Unit, Royal Brompton Hospital, London, UK.
George A
GA
Margaritopoulos
Dept of Thoracic Medicine and Laboratory of Molecular and Cellular Pneumonology, Interstitial Lung Disease Unit, University Hospital of Heraklion, Heraklion, Greece.
Eirini
E
Vasarmidi
Dept of Radiology, Royal Brompton Hospital, London, UK.
Joseph
J
Jacob
Interstitial Lung Disease Unit, Royal Brompton Hospital, London, UK.
Athol U
AU
Wells
Dept of Thoracic Medicine and Laboratory of Molecular and Cellular Pneumonology, Interstitial Lung Disease Unit, University Hospital of Heraklion, Heraklion, Greece kantoniou@med.uoc.gr.
Katerina M
KM
Antoniou
D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics / Q000378:metabolism / Q000628:therapy; D010641:Phenotype; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation; D000074606:Smoking Prevention; D014057:Tomography, X-Ray Computed
D005819:Genetic Markers