Long-term outcomes of catheter ablation of ventricular tachycardia in patients with structural heart disease.
BACKGROUND
Catheter ablation of ventricular tachycardia (VT) is feasible. However, the long-term outcomes for different underlying diseases have not been well defined.


METHODS
Eighty-eight consecutive patients who underwent catheter ablation of VT using a three-dimensional mapping system were analyzed. The primary endpoint was any VT or ventricular fibrillation (VF) recurrence. Secondary endpoints were a composite of death or any VT/VF recurrence. Underlying heart diseases were remote myocardial infarction (remote MI) in 51 patients and non-ischemic cardiomyopathy in 37 (arrhythmogenic right ventricular cardiomyopathy [ARVC] in 18 patients, and dilated cardiomyopathy [NIDCM] in 19).


RESULTS
Acute success was achieved in 82 of 88 (93%) patients. During a follow-up period of 39.2±4.6 months, VT recurred in 26 of 87 (30%), and VT/VF recurrence or death occurred in 39 of 87 (45%) patients. ARVC had better outcomes than NIDCM for the primary (p<0.05) and secondary endpoints (p<0.05). Remote MI-VT revealed a midrange outcome.


CONCLUSIONS
The long-term outcomes after catheter ablation of VT varied according to the underlying heart disease. ARVC-VT ablation was associated with better long-term prognosis than NIDCM. Remote MI-VT demonstrated a midrange outcome.
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Masahiko
M
Goya
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Masato
M
Fukunaga
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Ken-Ichi
K
Hiroshima
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Kentaro
K
Hayashi
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Yu
Y
Makihara
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Michio
M
Nagashima
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Yoshimori
Y
An
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Seiji
S
Ohe
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Kennosuke
K
Yamashita
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Kenji
K
Ando
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Hiroyoshi
H
Yokoi
Department of Cardiology, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Masashi
M
Iwabuchi
Department of Medical Engineering, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Kouji
K
Katayama
Department of Medical Engineering, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Tomoaki
T
Ito
Department of Medical Engineering, Kokura Memorial Hospital, Asano 3-2-1, Kokurakita-ku, Kitakyushu 802-8555, Japan.
Harushi
H
Niu
Arrhythmogenic right ventricular dysplasia/cardiomyopathy; Catheter ablation; Dilated cardiomyopathy; Remote myocardial infarction; Ventricular tachycardia