Decompressive craniectomy in severe traumatic brain injury: prognostic factors and complications.
OBJECTIVE
To analyze the clinical characteristics, complications and factors associated with the prognosis of severe traumatic brain injury among patients who undergo a decompressive craniectomy.


METHODS
Retrospective study of patients seen in an intensive care unit with severe traumatic brain injury in whom a decompressive craniectomy was performed between the years 2003 and 2012. Patients were followed until their discharge from the intensive care unit. Their clinical-tomographic characteristics, complications, and factors associated with prognosis (univariate and multivariate analysis) were analyzed.


RESULTS
A total of 64 patients were studied. Primary and lateral decompressive craniectomies were performed for the majority of patients. A high incidence of complications was found (78% neurological and 52% nonneurological). A total of 42 patients (66%) presented poor outcomes, and 22 (34%) had good neurological outcomes. Of the patients who survived, 61% had good neurological outcomes. In the univariate analysis, the factors significantly associated with poor neurological outcome were postdecompressive craniectomy intracranial hypertension, greater severity and worse neurological state at admission. In the multivariate analysis, only postcraniectomy intracranial hypertension was significantly associated with a poor outcome.


CONCLUSIONS
This study involved a very severe and difficult to manage group of patients with high morbimortality. Intracranial hypertension was a main factor of poor outcome in this population.
Universidad de la Republica Uruguay, Montevidéo, Uruguay.
Pedro
P
Grille
Instituto Nacional de Donación y Transplantes, Universidad de la Republica Uruguay, Montevidéo, Uruguay.
Nicolas
N
Tommasino
D000293:Adolescent; D000328:Adult; D000070642:Brain Injuries, Traumatic / Q000601:surgery*; D056424:Decompressive Craniectomy / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D019586:Intracranial Hypertension / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000453:epidemiology*; D011379:Prognosis; D012189:Retrospective Studies; D015599:Trauma Severity Indices; D016896:Treatment Outcome; D055815:Young Adult