The Surface Modification and Antimicrobial Activity of Basic Magnesium Hypochlorite Nanoparticles.
The basic magnesium hypochlorite (BMH) nanoparticles were prepared by two micro-emulsion techniques and modified with sodium stearate. The influences of the main technical parameters such as the addition amount of sodium stearate, reaction temperature and reaction time on the Lipophilic degree (LD) of the modified BMH nanoparticles were investigated. The characteristics of the BMH nanoparticles were analysed by means of Malvern Instruments, transmission electron microscopy (TEM), water contact angle measurements, Fourier transform infrared spectroscopy (FTIR) and thermogravimetry analysis (TGA). The antimicrobial activity of the modified BMH nanoparticles was investigated with the antibacterial circle test. The results showed that the average size of the BMH nanoparticles was 305 nm. The BMH nanoparticles had been successfully modified by sodium stearate and the LD of.the modified BMH nanoparticles was 8.4% when the addition amount of sodium stearate was 0.15 g, the reaction temperature was 10 °C and the reaction time was 5 h. The dispersibility and hydrophobicity of the modified BMH nanoparticles were improved and the contact angle was up to 103 °, the modified BMH nanoparticles still had excellent antimicrobial activity after modification.
Lijian
L
Xu
Zengmin
Z
Tang
Jianxiong
J
Xu
Jide
J
Zhang
Jingjing
J
Du
Na
N
Li
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D018407:Bacterial Physiological Phenomena / Q000187:drug effects*; D002470:Cell Survival / Q000187:drug effects; D006997:Hypochlorous Acid / Q000737:chemistry; D008274:Magnesium / Q000737:chemistry* / Q000494:pharmacology*; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D013229:Stearic Acids / Q000737:chemistry*; D013499:Surface Properties
D000900:Anti-Bacterial Agents; D013229:Stearic Acids; C031183:stearic acid; D006997:Hypochlorous Acid; D008274:Magnesium