Corneal infections in the 21st century.
Ninety years ago, the first issue of the Postgraduate Medical Journal published a review of an article written by Mr Robert Lindsay-Rea, a consultant ophthalmic surgeon in the Western Ophthalmic Hospital and an oculist in the West End Hospital for Nervous Diseases, entitled "A preliminary report on the treatment of keratitis". Today, microbial keratitis remains an important cause of avoidable visual impairment in the world. The aetiology of microbial keratitis has changed greatly over the past century due to the discovery of antibiotics, improvement in sanitation and education, the rising trend of contact lens wear and increased air travel. Significant advances have also been made in our understanding and management of this important disorder. This article highlights some of these changes and discusses the current management and research.
Department of Corneal and Ocular Surface Disease, The Western Eye Hospital, Imperial College Healthcare NHS Trust, London, UK.
Hon Shing
HS
Ong
Department of Corneal and Ocular Surface Disease, The Western Eye Hospital, Imperial College Healthcare NHS Trust, London, UK.
Melanie C
MC
Corbett
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001672:Biocompatible Materials; D003261:Contact Lenses / Q000009:adverse effects / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000453:epidemiology / Q000266:history / Q000473:pathology* / Q000628:therapy; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007634:Keratitis / Q000453:epidemiology / Q000266:history / Q000473:pathology* / Q000628:therapy; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D000091402:Prohibitins; D012307:Risk Factors; D016896:Treatment Outcome; D014792:Visual Acuity
D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D009883:Ophthalmic Solutions; C000717331:PHB2 protein, human; D000091402:Prohibitins
Advancement; Infection; Keratitis; Microbial; Treatment