Mefenamic acid: A possible cause of drug-induced acute pancreatitis.
BACKGROUND
Drug-induced acute pancreatitis (AP) is rare, but as there are no systematic data on it, the true incidence is not known.


METHODS
This case report is a first description of two episodes of AP occurring after administration and subsequent re-administration of mefenamic acid to a young woman without comorbidities. Other common causes of AP could be ruled out. With both episodes, the latency of AP was less than 24 h after drug intake.


CONCLUSIONS
Mefenamic acid should be considered as a possible cause of drug-induced AP.
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Austria.
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S
Wurm
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Austria.
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F
Schreiber
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Austria. Electronic address: walter.spindelboeck@medunigraz.at.
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W
Spindelboeck
D000208:Acute Disease; D000293:Adolescent; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008528:Mefenamic Acid / Q000009:adverse effects*; D010195:Pancreatitis / Q000139:chemically induced* / Q000175:diagnosis
D016861:Cyclooxygenase Inhibitors; D008528:Mefenamic Acid
Acute pancreatitis; Classification of drug-induced AP; Drug-induced acute-pancreatitis; Idiosyncratic drug reaction; Mefenamic acid; NSAIDs