Predictive Factors for Severe Outcomes in Ischemic Colitis.
OBJECTIVE
Ischemic colitis includes a wide clinical spectrum ranging from mild to severe forms. This study aimed to determine the factors that are related to the occurrence of severe ischemic colitis.


METHODS
This multicenter study was conducted retrospectively in Korea. The patients were divided into mild and severe groups. This study surveyed clinical characteristics, blood tests, endoscopic findings, and imaging studies.


RESULTS
In the comparison of comorbidities, the severe group had a higher ratio of chronic kidney disease than the mild group (p=0.001). In the blood test, the severe group had a reduced number of platelets (p=0.018) and a higher C-reactive protein value (p=0.001). The severe group had a higher ratio of involvement of the right colon (p=0.026). The Eastern Cooperative Oncology Group (ECOG) performance status score of the patients showed that the severe group had higher scores than the mild group (p=0.003). A multivariate analysis showed that chronic kidney disease and high ECOG performance status scores were significant risk factors.


CONCLUSIONS
If patients diagnosed with ischemic colitis are also treated for chronic kidney disease or have poor performance status, more attention and early intervention are necessary.
Department of Internal Medicine, Busan Hangun Hospital, Busan, Korea.
Seok Reyol
SR
Choi
Department of Internal Medicine, Inje University College of Medicine, Busan, Korea.
Sam Ryong
SR
Jee
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
Geun Am
GA
Song
Department of Internal Medicine, Kosin University Gospel Hospital, Busan, Korea.
Seun Ja
SJ
Park
Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
Jong Hun
JH
Lee
Department of Internal Medicine, Good Samsun Hospital, Busan, Korea.
Chul Soo
CS
Song
Department of Internal Medicine, Maryknoll Medical Center, Busan, Korea.
Hee Ug
HU
Park
D000368:Aged; D002097:C-Reactive Protein / Q000032:analysis; D017091:Colitis, Ischemic / Q000097:blood / Q000150:complications / Q000473:pathology*; D003106:Colon / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010976:Platelet Count; D051436:Renal Insufficiency, Chronic / Q000150:complications; D056910:Republic of Korea; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index
D002097:C-Reactive Protein
Colitis, ischemic; Outcome; Predictive factors