Boron Clusters as a Platform for New Materials: Synthesis of Functionalized o-Carborane (C2 B10 H12 ) Derivatives Incorporating DNA Fragments.
A synthetic strategy for functionalization of the three vertices of o-carborane and the attachment of the obtained triped to the solid support was developed. Further functionalization of the triped with short DNA sequences by automated DNA synthesis was achieved. The proposed methodology is a first example of boron cluster chemistry on a solid support opening new perspectives in boron cluster functionalization.
Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology Polish Academy of Sciences, Lodowa 106, 92-232 Lodz (Poland).
Slawomir
S
Janczak
Screening Laboratory, Institute of Medical Biology Polish Academy of Sciences, Lodowa 106, 92-232 Lodz (Poland).
Agnieszka
A
Olejniczak
Institute of Bioorganic Chemistry Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznan (Poland).
Sandra
S
Balabańska
Institute of Bioorganic Chemistry Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznan (Poland).
Marcin K
MK
Chmielewski
Institut de Ciència de Materials de Barcelona (CSIC), Campus de la U.A.B., 08193 Bellaterra (Spain).
Marius
M
Lupu
Institut de Ciència de Materials de Barcelona (CSIC), Campus de la U.A.B., 08193 Bellaterra (Spain).
Clara
C
Viñas
Laboratory of Molecular Virology and Biological Chemistry, Institute of Medical Biology Polish Academy of Sciences, Lodowa 106, 92-232 Lodz (Poland). sjanczak@cbm.pan.pl, zlesnikowski@cbm.pan.pl.
Zbigniew J
ZJ
Lesnikowski
D001880:Boranes / Q000138:chemical synthesis* / Q000737:chemistry; D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism
D001880:Boranes; D001896:Boron Compounds; D004247:DNA
DNA; boron clusters; conjugates; nanomaterials; tripeds