Polymyositis and fatal interstitial pneumonia following pelvic irradiation that led to unexpectedly severe adverse effects: a case report.
Interstitial pneumonia (IP) sometimes precedes collagen vascular disease (CVD) onset. A patient with bladder cancer and mild IP received pelvic irradiation and experienced unexpectedly severe urinary toxicity followed by polymyositis onset and fatal IP exacerbation. Careful observation for "alarm adverse effects" of radiotherapy in IP patients may help predicting CVD onset.
Department of Radiation Oncology, Sano Kousei General Hospital 1728, Horigome-cho, Sano, Tochigi, 327-0843, Japan ; Department of Radiation Oncology, Gunma University Graduate School of Medicine 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Takahiro
T
Oike
Department of Radiation Oncology, Sano Kousei General Hospital 1728, Horigome-cho, Sano, Tochigi, 327-0843, Japan ; Department of Radiation Oncology, Gunma University Graduate School of Medicine 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Tatsuya
T
Ohno
Department of Radiation Oncology, Sano Kousei General Hospital 1728, Horigome-cho, Sano, Tochigi, 327-0843, Japan ; Department of Radiation Oncology, Gunma University Graduate School of Medicine 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Katsuyuki
K
Shirai
Department of Internal Medicine, Sano Kousei General Hospital 1728, Horigome-cho, Sano, Tochigi, 327-0843, Japan.
Takashi
T
Inoue
Department of Radiation Oncology, Gunma University Graduate School of Medicine 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Takashi
T
Nakano
Collagen vascular disease; interstitial pneumonia; radiation toxicity