Blood Pressure Drop Prediction by using HRV Measurements in Orthostatic Hypotension.
Orthostatic Hypotension is defined as a reduction of systolic and diastolic blood pressure within 3 minutes of standing, and may cause dizziness and loss of balance. Orthostatic Hypotension has been considered an important risk factor for falls since 1960. This paper presents a model to predict the systolic blood pressure drop due to orthostatic hypotension, relying on heart rate variability measurements extracted from 5 minute ECGs recorded before standing. This model was developed and validated with the leave-one-out cross-validation technique involving 10 healthy subjects, and finally tested with an additional 5 healthy subjects, whose data were not used during the training and cross-validation process. The results show that the model predicts correctly the systolic blood pressure drop in 80 % of all experiments, with an error rate below the measurement error of a sphygmomanometer digital device.
Institute of High Performance Computing and Networking (ICAR - CNR), via pietro castellino, 111-80131, Naples, Italy, giovanna.sannino@na.icar.cnr.it.
Giovanna
G
Sannino
Paolo
P
Melillo
Saverio
S
Stranges
Giuseppe
G
De Pietro
Leandro
L
Pecchia
D000058:Accidental Falls / Q000517:prevention & control; D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D015203:Reproducibility of Results