Living with Restless Legs Syndrome/Willis-Ekbom Disease.
Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is commonly seen in patients with end-stage renal disease (ESRD), but this condition has not been properly recognized. The prevalence of RLS/WED in ESRD shows the ethnic variation (7%-68%), with the similar tendency of primary RLS/WED. Although RLS/WED in ESRD is defined in secondary RLS/WED, the factors of ESRD that are involved in the genesis of RLS/WED remain unknown. Even after renal transplantation, RLS/WED symptoms do not completely disappear, and genetic predisposition to RLS/WED may play an important role in causing RLS/WED. Long-term intervention for RLS/WED and ESRD will be necessary.
Center for Sleep-related Disorders, Kansai Electric Power Hospital, 2-1-7 Fukushima, Fukushima, Osaka 553-0003, Japan. Electronic address: nanaosaka@aol.com.
Naoko
N
Tachibana
D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy*; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy*
End-stage renal disease; Hemodialysis; Restless legs syndrome; Willis-Ekbom disease