Melanotic schwannoma of thoracic spinal root mimics metastatic melanoma: a potential pitfall for misdiagnosis.
Melanotic Schwannoma (MS) is a kind of rare subtypes of Schwannoma. In this tumor, amounts of melanin always mislead inexperienced pathologists to a diagnosis of primary or metastastic melanoma. Different from the ordinary Schwannoma, MS is considered as a low malignant nerve sheave tumor. Here we present a case of MS arising from the thoracic spinal and initially was misdiagnosed as metastastic melanoma. But the patient followed a benign course, without recurrent in 30 months follow-up.
Department of Pathology, Second Affiliated Hospital of Zhejiang University, Medical School Hangzhou 310009, China.
Baizhou
B
Li
Department of Pathology, Women's Hospital, Zhejiang University, School of Medicine Hangzhou 310006, China.
Qin
Q
Chen
D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D003951:Diagnostic Errors; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008544:Melanocytes / Q000737:chemistry / Q000473:pathology*; D008545:Melanoma / Q000556:secondary*; D008875:Middle Aged; D009442:Neurilemmoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D013125:Spinal Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D014408:Biomarkers, Tumor
Melanotic tumor; Schwannoma; diagnosis; differentiation; melanoma