The first total synthesis of (+)-goniothalesacetate and syntheses of (+)-altholactone, (+)-gonioheptolide A, and (-)-goniofupyrone by an asymmetric acetate aldol approach.
The first stereoselective total synthesis of (+)-goniothalesacetate and total synthesis of several bioactive styryl lactones, (+)-altholactone, (+)-gonioheptolide A, and (-)-goniofupyrone have been achieved from an advanced intermediate, which can be derived from L-(+)-DET.
Natural Products Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 607, India. gowravaramsr@yahoo.com sabitha@iict.res.in.
Sandeep
S
AnkiReddy
Praveen
P
AnkiReddy
Gowravaram
G
Sabitha
D000085:Acetates / Q000737:chemistry*; D000447:Aldehydes / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry
D000085:Acetates; D000447:Aldehydes; D005663:Furans; D007783:Lactones; D011753:Pyrones; C459359:altholactone; C000609656:goniofupyrone; C000609655:gonioheptolide A; C513807:goniothalesacetate; C116609:3-hydroxybutanal