Should I stay or should I go? Traffic control for plant pattern recognition receptors.
Plants employ cell surface-localised receptors to recognise potential invaders via perception of microbe-derived molecules. This is mediated by pattern recognition receptors (PRRs) that bind microbe-associated or damage-associated molecular patterns or perceive apoplastic effector proteins secreted by microorganisms. In either case, effective recognition and initiation of appropriate defence responses rely on a signalling competent pool of receptors at the cell surface. Maintenance of this pool of receptors at the plasma membrane is guaranteed by sorting of properly folded ligand-unbound and ligand-bound receptors via the secretory-endosomal network in an activation-dependent manner. Recent findings highlight that ligand-induced endocytosis is found across members of distinct PRR families suggesting a conserved mechanism by which PRRs and immunity is regulated.
The Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, United Kingdom.
Márcia
M
Frescatada-Rosa
The Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, United Kingdom. Electronic address: Silke.Robatzek@sainsbury-laboratory.ac.uk.
Silke
S
Robatzek
The Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, United Kingdom.
Hannah
H
Kuhn
D002462:Cell Membrane / Q000378:metabolism; D057865:Plant Immunity; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D010944:Plants / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D021381:Protein Transport; D011956:Receptors, Cell Surface / Q000235:genetics* / Q000378:metabolism; D051192:Receptors, Pattern Recognition / Q000235:genetics* / Q000378:metabolism
D010940:Plant Proteins; D011956:Receptors, Cell Surface; D051192:Receptors, Pattern Recognition