Electron string ion sources for carbon ion cancer therapy accelerators.
The type of the Electron String Ion Sources (ESIS) is considered to be the appropriate one to produce pulsed C(4+) and C(6+) ion beams for cancer therapy accelerators. In fact, the new test ESIS Krion-6T already now provides more than 10(10) C(4+) ions per pulse and about 5 × 10(9) C(6+) ions per pulse. Such ion sources could be suitable to apply at synchrotrons. It has also been found that Krion-6T can provide more than 10(11) C(6+) ions per second at the 100 Hz repetition rate, and the repetition rate can be increased at the same or larger ion output per second. This makes ESIS applicable at cyclotrons as well. ESIS can be also a suitable type of ion source to produce the (11)C radioactive ion beams. A specialized cryogenic cell was experimentally tested at the Krion-2M ESIS for pulse injection of gaseous species into the electron string. It has been shown in experiments with stable methane that the total conversion efficiency of methane molecules to C(4+) ions reached 5%÷10%. For cancer therapy with simultaneous irradiation and precise dose control (positron emission tomography) by means of (11)C, transporting to the tumor with the primary accelerated (11)C(4+) beam, this efficiency is preliminarily considered to be large enough to produce the (11)C(4+) beam from radioactive methane and to inject this beam into synchrotrons.
Joint Institute for Nuclear Research, Dubna 141980, Russia.
A Yu
AY
Boytsov
Joint Institute for Nuclear Research, Dubna 141980, Russia.
D E
DE
Donets
Joint Institute for Nuclear Research, Dubna 141980, Russia.
E D
ED
Donets
Joint Institute for Nuclear Research, Dubna 141980, Russia.
E E
EE
Donets
National Institute of Radiological Science, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.
K
K
Katagiri
National Institute of Radiological Science, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.
K
K
Noda
Joint Institute for Nuclear Research, Dubna 141980, Russia.
D O
DO
Ponkin
Joint Institute for Nuclear Research, Dubna 141980, Russia.
A Yu
AY
Ramzdorf
Joint Institute for Nuclear Research, Dubna 141980, Russia.
V V
VV
Salnikov
Joint Institute for Nuclear Research, Dubna 141980, Russia.
V B
VB
Shutov
D004583:Electrons; D063193:Heavy Ion Radiotherapy / Q000295:instrumentation*; D060526:Magnetic Fields; D009369:Neoplasms / Q000532:radiotherapy*; D010315:Particle Accelerators / Q000295:instrumentation*