Cross-cultural adaptation and validation of the Behcet's Disease Current Activity Form in Korea.
OBJECTIVE
This study was undertaken to perform a cross-cultural adaptation of the Behcet's Disease Current Activity Form (BDCAF, version 2006) questionnaire to the Korean language and to evaluate its reliability and validity in a population of Korean patients with Behcet's disease (BD).


METHODS
A cross-cultural study was conducted among patients with BD who attended our rheumatology clinic between November 2012 and March 2013. There were 11 males and 35 females in the group. The mean age of the participants was 48.5 years and the mean disease duration was 6.4 years. The first BDCAF questionnaire was completed on arrival and the second assessment was performed 20 minutes later by a different physician. The test-retest reliability was analyzed by computing κ statistics. Kappa scores of > 0.6 indicated a good agreement. To assess the validity, we compared the total BDCAF score with the patient's/clinician's perception of disease activity and the Korean version of the Behcet's Disease Quality of Life (BDQOL).


RESULTS
For the test-retest reliability, good agreements were achieved on items such as headache, oral/genital ulceration, erythema, skin pustules, arthralgia, nausea/vomiting/abdominal pain, and diarrhea with altered/frank blood per rectum. Moderate agreement was observed for eye and nervous system involvement. We achieved a fair agreement for arthritis and major vessel involvement. Significant correlations were obtained between the total BDCAF score with the BDQOL and the patient's/clinician's perception of disease activity p < 0.05).


CONCLUSIONS
The Korean version of the BDCAF is a reliable and valid instrument for measuring current disease activity in Korean BD patients.
Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.
Hyo Jin
HJ
Choi
Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.
Mi Ryoung
MR
Seo
Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.
Hee Jung
HJ
Ryu
Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.
Han Joo
HJ
Baek
D000328:Adult; D044466:Asian People / Q000523:psychology; D001528:Behcet Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D032882:Comprehension; D003466:Cultural Characteristics; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D056910:Republic of Korea / Q000453:epidemiology; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
Behcet syndrome; Behcet’s Disease Current Activity Form; Cross-cultural adaptation