Allergic delayed drug hypersensitivity is more frequently diagnosed in drug reaction, eosinophilia and systemic symptoms (DRESS) syndrome than in exanthema induced by beta-lactam antibiotics.
Allergy and Clinical Immunology Department, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, France.
Benoit
B
Ben-Said
Allergy and Clinical Immunology Department, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, France.
Ségolène
S
Arnaud-Butel
Université de Lyon, France.
Aurore
A
Rozières
CIRI - INSERM U1111 - CNRS UMR5308, Université Lyon 1, ENS, 21 Avenue Tony Garnier, 69365 Lyon Cedex 07, France.
Karen
K
Rodet
Allergy and Clinical Immunology Department, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, France; Université de Lyon, France; CIRI - INSERM U1111 - CNRS UMR5308, Université Lyon 1, ENS, 21 Avenue Tony Garnier, 69365 Lyon Cedex 07, France.
Frédéric
F
Bérard
Allergy and Clinical Immunology Department, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, France; Université de Lyon, France; CIRI - INSERM U1111 - CNRS UMR5308, Université Lyon 1, ENS, 21 Avenue Tony Garnier, 69365 Lyon Cedex 07, France.
Jean-François
JF
Nicolas
Allergy and Clinical Immunology Department, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, France; Université de Lyon, France; CIRI - INSERM U1111 - CNRS UMR5308, Université Lyon 1, ENS, 21 Avenue Tony Garnier, 69365 Lyon Cedex 07, France. Electronic address: nosbaumaudrey@yahoo.fr.
Audrey
A
Nosbaum
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D063926:Drug Hypersensitivity Syndrome / Q000453:epidemiology* / Q000209:etiology; D005076:Exanthema / Q000139:chemically induced / Q000453:epidemiology*; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D055815:Young Adult; D047090:beta-Lactams / Q000009:adverse effects*
D047090:beta-Lactams
Beta-lactams; Drug allergy; Drug-specific T cells; ELISPOT assay; Hypersensitivity; Skin tests