Ameloblastomatous Change in Radicular Cyst of The Jaw in a Nigerian Population.
OBJECTIVE
To determine the incidence, age, gender, jaw-sites and subtypes of radicular cyst, and to determine the incidence of ameloblastomatous change in radicular cyst in a Nigerian population.


METHODS
A 10-year retrospective analysis of all diagnosed orofacial lesions in the Department of Oral Pathology and Medicine, University of Benin Teaching Hospital, Benin City, Nigeria.


RESULTS
From the 785 diagnosed orofacial lesions within the study period; there were 54 (6.9%) cases of radicular cysts of the jaws. The peak age group was the 3(rd) decade (n=23, 42.6%) with a mean age of 31 ± 1.7 years. There were 29 (53.7%) males and 25 (46.3%) females, giving a ratio of 1.2:1. The mandible was the commonest jaw-site (n=32, 59.3%). There were 12 (22.2%) cases of periapical cyst which were significantly associated with anterior maxillary site (n=8, 14.8%) [p=0.001]. Seven (13.0%) cases of cystic ameloblastoma were diagnosed among the radicular cysts, with a predilection of the lesions for 3(rd) and 4(th) decades of life (n=6, 11.1%), and posterior mandible (n=5, 9.3%).


CONCLUSIONS
This study showed a low incidence of radicular cyst of the jaw among orofacial lesions and a relatively higher incidence of ameloblastomatous change in radicular cyst compared to previous reports. Immuno-histochemical examination is recommended to differentiate radicular cyst with ameloblastomatous-like change from cystic ameloblastoma arising from radicular cyst.
Department of Oral Pathology/Oral Medicine, University of Benin Teaching Hospital, PMB 1111 , Benin, Edo 30000, 1 Nigeria.
F O
FO
Omoregie
Department of Restorative Dentistry, University of Benin Teaching Hospital, PMB 1111 , Benin, Edo 30000, 1 Nigeria.
M A
MA
Sede
Department of Oral Pathology/Oral Medicine, University of Benin Teaching Hospital, PMB 1111 , Benin, Edo 30000, 1 Nigeria.
A M
AM
Ojo
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000564:Ameloblastoma / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007570:Jaw Cysts / Q000453:epidemiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D011842:Radicular Cyst / Q000453:epidemiology / Q000473:pathology*; D012189:Retrospective Studies; D017678:Sex Distribution; D055815:Young Adult
Ameloblastomatous change; Immunohistochemistry; Inflammation; Jaw lesion; Radicular cyst