B(C6F5)3: A New Class of Strong and Bulky Lewis Acid for Exo-Selective Intermolecular Diels-Alder Reactions of Unreactive Acyclic Dienes with α,β-Enals.
Lewis acid B(C6F5)3 catalyzed the Diels-Alder reactions of multisubstituted open-chain dienes and α,β-enals to afford the desired products with high exo-selectivities are reported. The substituent effect of the dienes and dienophiles on the product's stereoselectivity was thoroughly investigated, and it was found that most of the desired exo-Diels-Alder products could be obtained in good yields and with high exo-stereoselectivities.
Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
Jia-Hui
JH
Zhou
Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
Bing
B
Jiang
Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
Fei-Fan
FF
Meng
Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.
Yun-He
YH
Xu
Department of Chemistry, University of Science and Technology of China , Hefei 230026, China.|Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University , Singapore 637371.
Teck-Peng
TP
Loh