Serum Lipid Levels in Pseudoexfoliation Syndrome.
OBJECTIVE
To investigate the serum lipid levels in pseudoexfoliation (PEX) syndrome and its association with systemic vascular disorders.


METHODS
Patients were divided into three groups: 52 patients with PEX syndrome (group 1), 20 patients with PEX glaucoma (group 2), and 47 control subjects without PEX syndrome or glaucoma (group 3). The fasting serum total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglyceride levels were evaluated by Beckman Coulter DXC 800/USA biochemical analyzer.


RESULTS
The mean LDL values were 138 ± 33 mg/dl in group 1, 150 ± 37 mg/dl in group 2, and 127 ± 36 mg/dl in group 3. The mean LDL values in groups 1 and 2 were found to be significantly higher than that of group 3 (p = 0.04). The patients in groups 1 and 2 were more often diabetic and hypertensive than group 3 (p < 0.008, p < 0.005, respectively).


CONCLUSIONS
Increased LDL values are significantly associated with PEX.
a Department of Ophthalmology , Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital , Ankara , Turkey.
Bengi Ece
BE
Kurtul
b Department of Cardiology , Ankara Training and Research Hospital , Ankara , Turkey.
Alparslan
A
Kurtul
a Department of Ophthalmology , Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital , Ankara , Turkey.
Pinar
P
Altiaylik Ozer
a Department of Ophthalmology , Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital , Ankara , Turkey.
Emrah Utku
EU
Kabatas
a Department of Ophthalmology , Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital , Ankara , Turkey.
Gokce Tasdemir
GT
Ertugrul
D000368:Aged; D015415:Biomarkers / Q000097:blood; D003430:Cross-Sectional Studies; D017889:Exfoliation Syndrome / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D014652:Vascular Diseases / Q000097:blood / Q000150:complications*
D015415:Biomarkers; D008055:Lipids
Low-density lipoprotein; pseudoexfoliation glaucoma; pseudoexfoliation syndrome; serum lipids; vascular diseases