Pulse Wave Velocity: A Valuable Predictor for Cardio-Cerebrovascular Disease and Death in PD Patients.
OBJECTIVE
To evaluate the value of pulse wave velocity (PWV) to predict cardio-cerebrovascular (CVD) and death in peritoneal dialysis (PD) patients.


METHODS
In all, 59 maintenance PD patients from January 2012 to December 2012 were enrolled. Patients were classified as group A (>9 m/s) and group B (≤9 m/s), based on the results of carotid-femoral PWV (CF-PWV).


RESULTS
CF-PWV was positively correlated with age (r = 0.71, p < 0.01), left atrial diameter (r = 0.58, p < 0.01), left ventricular mass index (r = 0.59, p < 0.01) and 24H average systolic blood pressure (SBP) (r = 0.57, p < 0.01). Age (relative risk (RR) 1.086, 95% confidence interval (CI) 1.024-1.153, p < 0.01) and 24H average SBP (RR 1.047, 95% CI 1.013-1.082, p < 0.01) were risk factors of higher CF-PWV. The cumulative and new CVD free survival rates of group A significantly decreased. Elder (RR 1.114, 95% CI 1.013-1.224, p = 0.026) and higher PWV (RR 1.482, 95% CI 1.01-2.176, p = 0.044) were risk factors of CVD in PD patients.


CONCLUSIONS
PWV is a valuable predictor of CVD and death in PD patients.
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tian
T
Xu
Jingyuan
J
Xie
Xue
X
Zong
Weiming
W
Wang
Hong
H
Ren
Nan
N
Chen
D000328:Adult; D000367:Age Factors; D000368:Aged; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality* / Q000628:therapy; D002339:Carotid Arteries / Q000503:physiopathology; D005260:Female; D005263:Femoral Artery / Q000503:physiopathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis* / Q000401:mortality* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D011379:Prognosis; D011446:Prospective Studies; D011673:Pulsatile Flow; D063177:Pulse Wave Analysis / Q000401:mortality*; D012044:Regression Analysis; D012307:Risk Factors; D016019:Survival Analysis; D059289:Vascular Stiffness