Brain Energy Metabolism: Conserved Functions of Glycolytic Glial Cells.
The discovery in mammals that axons are metabolically supported by myelinating glial cells explains why neurons can extend meters in length. In this issue, Volkenhoff et al. (2015) show that, in Drosophila, the transfer of lactate from the glial to the neuronal compartment is conserved in evolution, independent of body size.
Max Planck Institute of Experimental Medicine, Department of Neurogenetics, 37075 Göttingen, Germany.
Andrea
A
Trevisiol
Max Planck Institute of Experimental Medicine, Department of Neurogenetics, 37075 Göttingen, Germany. Electronic address: nave@em.mpg.de.
Klaus-Armin
KA
Nave
D000818:Animals; D001812:Blood-Brain Barrier / Q000378:metabolism*; D004330:Drosophila / Q000502:physiology*; D005260:Female; D006019:Glycolysis; D009457:Neuroglia / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D014199:Trehalose / Q000378:metabolism*
D014199:Trehalose