Performance of the Automated Neuropsychological Assessment Metrics (ANAM) in detecting cognitive impairment in heart failure patients.
OBJECTIVE
Evaluate capacity of the Automated Neuropsychological Assessment Metrics (ANAM) to detect cognitive impairment (CI) in heart failure (HF) patients.


BACKGROUND
CI is a key prognostic marker in HF. Though the most widely used cognitive screen in HF, the Mini-Mental State Examination (MMSE) is insufficiently sensitive. The ANAM has demonstrated sensitivity to cognitive domains affected by HF, but has not been assessed in this population.


METHODS
Investigators administered the ANAM and MMSE to 57 HF patients, compared against a composite model of cognitive function.


RESULTS
ANAM efficiency (p < .05) and accuracy scores (p < .001) successfully differentiated CI and non-CI. ANAM efficiency and accuracy scores classified 97.7% and 93.0% of non-CI patients, and 14.3% and 21.4% with CI, respectively.


CONCLUSIONS
The ANAM is more effective than the MMSE for detecting CI, but further research is needed to develop a more optimal cognitive screen for routine use in HF patients.
Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address: susan.xie@bcm.edu.
Susan S
SS
Xie
Kent State University, Kent, OH 44242, USA; Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
Carly M
CM
Goldstein
Kent State University, Kent, OH 44242, USA.
Emily C
EC
Gathright
Kent State University, Kent, OH 44242, USA.
John
J
Gunstad
Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH 44106, USA.
Mary A
MA
Dolansky
Summa Health System, Akron, OH 44304, USA.
Joseph
J
Redle
Kent State University, Kent, OH 44242, USA; Summa Health System, Akron, OH 44304, USA.
Joel W
JW
Hughes
D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D005260:Female; D006333:Heart Failure / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011379:Prognosis
ANAM; Cognition; Heart failure; Mass screening; Mild cognitive impairment