Pseudo-Multicomponent Reactions of Arynes with N-Aryl Imines.
Pseudo-three-component reactions are described for the conversion of simple N-aryl imines into 1,2-dihydroisoquinoline-type products. The approach relies on a regioselective cascade reaction involving two equivalents of the aryne component iteratively as a dienophile and as an electrophile. Some examples of related, more complex pseudo-four-component cascade processes are also reported.
Aix Marseille Université , Centrale Marseille, CNRS, iSm2 UMR 7313 13397, Marseille, France.
Juan-Carlos
JC
Castillo
Universidad del Valle , Departamento de Química, A.A. 25360, Cali, Colombia.
Jairo
J
Quiroga
Universidad del Valle , Departamento de Química, A.A. 25360, Cali, Colombia.
Rodrigo
R
Abonia
Aix Marseille Université , Centrale Marseille, CNRS, iSm2 UMR 7313 13397, Marseille, France.
Jean
J
Rodriguez
Aix Marseille Université , Centrale Marseille, CNRS, iSm2 UMR 7313 13397, Marseille, France.
Yoann
Y
Coquerel