[VISIBLE LIGHT AND HUMAN SKIN (REVIEW)].
Biological effect of a visible light depends on extend of its property to penetrate into the tissues: the greater is a wavelength the more is an effect of a radiation. An impact of a visible light on the skin is evident by wave and quantum effects. Quanta of a visible radiation carry more energy than infrared radiation, although an influence of such radiation on the skin is produced by the light spectrum on the boarder of the ultraviolet and the infrared rays and is manifested by thermal and chemical effects. It is determined that large doses of a visible light (405-436 nm) can cause skin erythema. At this time, the ratio of generation of free radicals in the skin during an exposure to the ultraviolet and the visible light range from 67-33% respectively. Visible rays of 400-500 nm length of wave cause an increase of the concentration of oxygen's active form and mutation of DNA and proteins in the skin. The urticaria in 4-18% of young people induced by photodermatosis is described. As a result of a direct exposure to sunlight photosensitive eczema is more common in elderly. Special place holds a hereditary disease - porphyria, caused by a visible light. In recent years, dermatologists widely use phototherapy. The method uses polychromatic, non-coherent (wavelength of 515-1200 nm) pulsating beam. During phototherapy/light treatment a patient is being exposed to sunlight or bright artificial light. Sources of visible light are lasers, LEDs and fluorescent lamps which have the full range of a visible light. Phototherapy is used in the treatment of acne vulgaris, seasonal affective disorders, depression, psoriasis, eczema and neurodermities. LED of the red and near infrared range also is characterized by the therapeutic effect. They have an ability to influence cromatophores and enhance ATP synthesis in mitochondria. To speed up the healing of wounds and stimulate hair growth light sources of a weak intensity are used. The light of blue-green spectrum is widely used for the treatment of neonatal hyperbilirubinemy. A photodynamic therapy takes a special place. The third generation of the blue (410 nm), yellow (595 nm) and red photosensitors are used. Photodynamic therapy is used in the treatment of cancer as well.
Tbilisi State Medical University; I. Javakhishvili Tbilisi State University, Georgia.
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A
Tsibadze
Tbilisi State Medical University; I. Javakhishvili Tbilisi State University, Georgia.
E
E
Chikvaidze
Tbilisi State Medical University; I. Javakhishvili Tbilisi State University, Georgia.
A
A
Katsitadze
Tbilisi State Medical University; I. Javakhishvili Tbilisi State University, Georgia.
I
I
Kvachadze
Tbilisi State Medical University; I. Javakhishvili Tbilisi State University, Georgia.
N
N
Tskhvediani
Tbilisi State Medical University; I. Javakhishvili Tbilisi State University, Georgia.
A
A
Chikviladze
D000152:Acne Vulgaris / Q000453:epidemiology / Q000473:pathology; D004485:Eczema / Q000453:epidemiology / Q000473:pathology*; D004890:Erythema / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D007259:Infrared Rays / Q000009:adverse effects; D010789:Phototherapy / Q000009:adverse effects; D012867:Skin / Q000473:pathology / Q000528:radiation effects*; D013472:Sunlight / Q000009:adverse effects; D014466:Ultraviolet Rays / Q000009:adverse effects; D014581:Urticaria / Q000453:epidemiology / Q000473:pathology*