A Randomized Controlled Trial of Puncturing and Bloodletting at Twelve Hand Jing Points to Treat Acute Carbon Monoxide Poisoning as Adjunct to First Aid Treatment: A Study Protocol.
Background. Acute carbon monoxide poisoning (ACOP) is a significant cause of morbidity and mortality in many countries. Twelve Hand Jing Points (THJP) have been believed to be effective to treat all kinds of emergency calls in traditional Chinese medicine (TCM) for more than 3000 years. This randomized controlled trial (RCT) is designed to evaluate the effectiveness of THJP in curing acute carbon monoxide poisoning in first aid treatment. This paper reports the protocol of the trial. Methods/Design. This RCT is a multicenter, randomized, controlled study undergoing in China. The compliant patients are divided into the bloodletting group and standard of care group. With first aid treatments given to both of the groups, the bloodletting group is bleeding at THJP upon being hospitalized. Primary outcomes and secondary outcomes will be measured and compared between these two groups. Before treatment, immediately after treatment, and 30 minutes, 1 hour, and 4 hours after treatment, patients' basic vital signs and state of consciousness were observed. Before treatment and 1 and 4 hours after treatment, carboxyhemoglobin concentration in venous blood samples was detected. Discussion. The objective of this study is to provide convincing evidence to clarify the efficacy and safety of THJP for early treatment of acute carbon monoxide poisoning.
Clinical Teaching and Training Department, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China ; College of Acupuncture-Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Ying
Y
Yue
College of Acupuncture-Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Xingfang
X
Pan
Neurosurgery and Neurology Hospital, Affiliated Hospital, Logistics University of the Chinese People's Armed Police Force, Tianjin 300162, China.
Sai
S
Zhang
International Education College, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Jun
J
Jin
Clinical Teaching and Training Department, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Wei
W
Wang
Department of Integration Traditional and Western Medicine, Tianjin First Central Hospital, Tianjin 300192, China.
Dongqiang
D
Wang
Emergency Department, Wuqing Affiliated Hospital, Tianjin University of Traditional Chinese Medicine, Tianjin 301700, China.
Dexin
D
Han
Emergency Department, Tianjin Binhai New Area Dagang Hospital, Tianjin 300270, China.
Guirong
G
Wang
Neurosurgery and Neurology Hospital, Affiliated Hospital, Logistics University of the Chinese People's Armed Police Force, Tianjin 300162, China.
Qunliang
Q
Hu
Neurosurgery and Neurology Hospital, Affiliated Hospital, Logistics University of the Chinese People's Armed Police Force, Tianjin 300162, China.
Jingqing
J
Kang
College of Acupuncture-Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Shasha
S
Ding
Research Centre for Standardization of Acupuncture-Moxibustion, School of Language and Culture, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Yi
Y
Yang
College of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Huaien
H
Bu
College of Acupuncture-Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Yi
Y
Guo