Association between adiposity indicators, metabolic parameters and inflammatory markers in a sample of female adolescents.
OBJECTIVE
The aim of this study was to investigate the association between total and abdominal adiposity with metabolic parameters and inflammatory markers, in female adolescents.


METHODS
The sample consisted of 53 adolescents aged 13 to 17 years from a public school in Curitiba, Brazil. The adiposity indicators studied were body mass index (BMI), waist circumference (WC), trunk fat mass (TKFM), total fat mass (TFM) and body fat percentage (BF%) measured by dual-energy X-ray absorptiometry. The metabolic and inflammatory parameters studied were systolic blood pressure (SBP), diastolic blood pressure (DBP), glucose, insulin, homeostasis model assessment index for insulin resistance (HOMA-IR), lipids, C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), leptin, adiponectin and resistin.


RESULTS
Eighty percent of WC variation, 87% of TKFM and TFM, and 73% of BF% were predicted by BMI variation. There was a significant positive correlation between all indicators of adiposity with SBP, DBP, insulin, HOMA-IR, CRP and leptin. Triglycerides were positively correlated with BMI and WC, and adiponectin correlated negatively with BMI. TNF-α, IL-6, glucose, total cholesterol, and high- and low-density lipoprotein cholesterol did not correlate to the studied variables.


CONCLUSIONS
BMI showed a significant association with most of the parameters studied, and WC was slightly better than BMI to predict insulin resistance in this specific population.
Universidade Federal do Paraná, Curitiba, PR, BR.
Priscilla Rizental
PR
Coutinho
Departamento de Educação Física, UFPR, Curitiba, PR, BR.
Neiva
N
Leite
Faculdade de Educação Física, Universidade Estadual de Campinas, Campinas, SP, BR.
Wendell Arthur
WA
Lopes
Departamento de Educação Física, UFPR, Curitiba, PR, BR.
Larissa Rosa
LR
da Silva
Departamento de Educação Física, UFPR, Curitiba, PR, BR.
Cássio M
CM
Consentino
Departamento de Educação Física, UFPR, Curitiba, PR, BR.
Cristiane T
CT
Araújo
Departamento de Educação Física, UFPR, Curitiba, PR, BR.
Frederico B
FB
Moraes
Departamento de Educação Física, UFPR, Curitiba, PR, BR.
Incare C
IC
de Jesus
Faculdade de Educação Física, Universidade Estadual de Campinas, Campinas, SP, BR.
Cláudia Regina
CR
Cavaglieri
Universidade Federal do Paraná, Curitiba, PR, BR.
Rosana Bento
RB
Radominski
D050153:Abdominal Fat / Q000503:physiopathology*; D050154:Adiposity / Q000502:physiology*; D000293:Adolescent; D015415:Biomarkers / Q000097:blood*; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002318:Cardiovascular Diseases; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood* / Q000503:physiopathology; D008055:Lipids / Q000097:blood; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
D015415:Biomarkers; D008055:Lipids; D014280:Triglycerides