Preparation, characterization and electrochemical application of Ag-ZnO nanoplates for voltammetric determination of glutathione and tryptophan using modified carbon paste electrode.
Ag-ZnO nanoplates and 2-chlorobenzoyl ferrocene were synthesized and used to construct a modified carbon paste electrode. The electrooxidation of glutathione at the surface of the modified electrode was studied. Under the optimized conditions, the square wave voltammetric (SWV) peak current of glutathione increased linearly with glutathione concentrations in the range of 5.0 × 10(-8) to 2.0 × 10(-4)M with sensitivity of 0.659 μA μM(-1) and method detection limit of 20.0 nM was obtained for glutathione. The prepared modified electrode exhibits a very good resolution between the voltammetric peaks of glutathione and tryptophan which makes it suitable for the detection of glutathione in the presence of tryptophan in real samples.
Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran. Electronic address: h.beitollahi@yahoo.com.
Hadi
H
Beitollahi
Department of Chemistry, Graduate University of Advanced Technology, Kerman, Iran.
Abbas
A
Gholami
Center of Excellence in Electrochemistry, University of Tehran, Tehran, Iran; Biosensor Research Center, Endocrinology & Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Reza
MR
Ganjali
D015374:Biosensing Techniques / Q000295:instrumentation; D002244:Carbon / Q000737:chemistry; D045424:Complex Mixtures / Q000032:analysis / Q000737:chemistry; D003217:Conductometry / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005978:Glutathione / Q000737:chemistry / Q000652:urine*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D008839:Microelectrodes; D009824:Ointments; D012834:Silver / Q000737:chemistry; D014364:Tryptophan / Q000737:chemistry / Q000652:urine*; D015034:Zinc Oxide / Q000737:chemistry*
D045424:Complex Mixtures; D009824:Ointments; D012834:Silver; D002244:Carbon; D014364:Tryptophan; D005978:Glutathione; D015034:Zinc Oxide
Ag–ZnO nanoplates; Electrochemical sensors; Glutathione; Tryptophan