From Eye Drops to ICU, a Case Report of Three Side Effects of Ophthalmic Timolol Maleate in the Same Patient.
Timolol Maleate (also called Timolol) is a nonselective beta-adrenergic blocker and a class II antiarrhythmic drug, which is used to treat intraocular hypertension. It has been reported to cause systemic side effects especially in elderly patients with other comorbidities. These side effects are due to systemic absorption of the drug and it is known that Timolol is measurable in the serum following ophthalmic use. Chances of life threatening side effects increase if these are coprescribed with other cardiodepressant drugs like calcium channel or systemic beta blockers. We report a case where an elderly patient was admitted with three side effects of Timolol and his condition required ICU admission with mechanical ventilation and temporary transvenous pacing. The case emphasizes the need of raising awareness among physicians of such medications about the potential side effects and drug interactions. A close liaison among patient's physicians is suggested.
King's Mill Hospital, Nottinghamshire NG17 4JL, UK.
Muhammad Asim
MA
Rana
Department of Intensive Care Medicine, King Saud Medical City, Riyadh 11373, Saudi Arabia.
Ahmed Fouad
AF
Mady
Department of Intensive Care Medicine, King Saud Medical City, Riyadh 11373, Saudi Arabia.
Basheer Abdel
BA
Rehman
Department of Intensive Care Medicine, King Saud Medical City, Riyadh 11373, Saudi Arabia.
Abdulrahman
A
Alharthy
Department of Intensive Care Medicine, King Saud Medical City, Riyadh 11373, Saudi Arabia.
Basim
B
Huwait
King's Mill Hospital, Nottinghamshire NG17 4JL, UK.
Asim
A
Riaz
Department of Intensive Care Medicine, King Saud Medical City, Riyadh 11373, Saudi Arabia.
Waleed Tharwat
WT
Aletreby