Magnetic nanoparticles for magnetic drug targeting.
Nanomedicine and superparamagnetic iron oxide nanoparticles (SPIONs) are thought to have an important impact on medicine in the future. Especially in cancer therapy, SPIONs offer the opportunity of improving the effectivity of the treatment and reduce side effects by magnetic accumulation of SPION-bound chemotherapeutics in the tumor area. Although still some challenges have to be overcome, before the new treatment concept of magnetic drug targeting will reach the patients, substantial progress has been made, and promising results were shown in the last years.
Stefan
S
Lyer
Raminder
R
Singh
Rainer
R
Tietze
Christoph
C
Alexiou
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000737:chemistry; D003692:Delayed-Action Preparations / Q000008:administration & dosage* / Q000737:chemistry / Q000528:radiation effects; D006801:Humans; D058185:Magnetite Nanoparticles / Q000737:chemistry* / Q000528:radiation effects / Q000648:ultrastructure; D058990:Molecular Targeted Therapy / Q000379:methods*; D053769:Nanocapsules / Q000737:chemistry* / Q000528:radiation effects / Q000648:ultrastructure; D009369:Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents; D003692:Delayed-Action Preparations; D058185:Magnetite Nanoparticles; D053769:Nanocapsules