C-Reactive Protein in Peripheral Blood of Patients with Chronic and Aggressive Periodontitis, Gingivitis, and Gingival Recessions.
CRP is a plasma protein that reflects a measure of the acute phase response to inflammation and is one of the markers of choice in monitoring this response. CRP can be used for the prediction and early detection of periodontal disease. The aim of this study was to compare and evaluate the systemic levels of CRP in the peripheral blood samples of patients with chronic and aggressive periodontitis, gingivitis, and gingival recessions and compare them with periodontal clinical parameters. All patients (N = 158) were examined prior to the initiation of periodontal treatment. Patients were divided into four groups. Group A consisted of 26 patients with aggressive periodontitis, Group B consisted of 111 patients with chronic periodontitis, Group C consisted of 13 patients with gingivitis, and Group D consisted of 8 patients with gingival recessions. Our study results indicate that CRP levels increase subsequently with the severity of the periodontal disease and that the bleeding on probing index showed much better positive correlation with the CRP levels compared to the pocket depth index in both periodontitis patients groups, especially in aggressive periodontitis patients.
School of Dental Medicine, First Faculty of Medicine and General University Hospital, Charles University, Karlovo Náměstí 32, Katerinska 32, 121 11 Prague, Czech Republic.
Stepan
S
Podzimek
School of Dental Medicine, First Faculty of Medicine and General University Hospital, Charles University, Karlovo Náměstí 32, Katerinska 32, 121 11 Prague, Czech Republic.
Jaroslav
J
Mysak
School of Dental Medicine, First Faculty of Medicine and General University Hospital, Charles University, Karlovo Náměstí 32, Katerinska 32, 121 11 Prague, Czech Republic.
Tatjana
T
Janatova
School of Dental Medicine, First Faculty of Medicine and General University Hospital, Charles University, Karlovo Náměstí 32, Katerinska 32, 121 11 Prague, Czech Republic.
Jana
J
Duskova
D000328:Adult; D010520:Aggressive Periodontitis / Q000378:metabolism*; D002097:C-Reactive Protein / Q000378:metabolism*; D055113:Chronic Periodontitis / Q000378:metabolism*; D005260:Female; D005889:Gingival Recession / Q000378:metabolism*; D005891:Gingivitis / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged
D002097:C-Reactive Protein