Extraskeletal Osteosarcoma Induced by a Foreign Body Granuloma.
An 8 yr old spayed female Italian greyhound was presented with a mass in the cranial abdomen. Preliminary evaluation of the dog revealed a large, cavitary, irregularly shaped mass with no definitive association with any abdominal organs. During an exploratory celiotomy, a 16 cm × 12 cm × 6 cm mass was removed. On subsequent histopathology, extraskeletal osteosarcoma induced by a foreign body granuloma was diagnosed. The foreign body granuloma, based on histopathological findings, was suspected to be secondary to a retained surgical sponge from her routine ovariohysterectomy performed 7 yr prior to presentation. Animals with granulomas induced by foreign bodies can remain asymptomatic for years; however, those granulomas can progress to extraskeletal osteosarcomas, which carry a poor prognosis.
From the Department of Veterinary Clinical Sciences (J.E.S., N.R.K.) and Department of Veterinary Pathology (J.H.), College of Veterinary Medicine, Iowa State University, Ames, IA.
Jennifer E
JE
Slovak
From the Department of Veterinary Clinical Sciences (J.E.S., N.R.K.) and Department of Veterinary Pathology (J.H.), College of Veterinary Medicine, Iowa State University, Ames, IA.
Nina R
NR
Kieves
From the Department of Veterinary Clinical Sciences (J.E.S., N.R.K.) and Department of Veterinary Pathology (J.H.), College of Veterinary Medicine, Iowa State University, Ames, IA.
Joseph
J
Haynes
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D004285:Dogs; D005260:Female; D005547:Foreign Bodies / Q000150:complications / Q000662:veterinary; D015745:Granuloma, Foreign-Body / Q000150:complications / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D012516:Osteosarcoma / Q000188:drug therapy / Q000209:etiology / Q000601:surgery / Q000662:veterinary*; D010894:Piroxicam / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010894:Piroxicam