Theoretical study on the bactericidal nature of nanopatterned surfaces.
A natural biomaterial has been discovered with bactericidal activities, which is mainly attributed to its nanopatterned surface structure. The surface of Clanger cicada (Psaltoda claripennis) wings has been identified as a natural bactericidal material, which has lead to the emergence of research on the development of novel antibacterial surfaces. From the interactions between bacterial biofilms and nanopatterned surface structures, a new mechanical model is proposed that investigates the rupture of bacterial cells within the framework of the "stretching" theory. The effect of surface nanoroughness on the survival of bacterial cells is evaluated by determining the stretching ability of their cell walls. The results, calculated using Gram-positive and Gram-negative bacteria as examples, show a correlation between the stretching of the cell wall and the geometric parameters of the surface structures. The theoretical results indicate that for a given cell rigidity, the bactericidal nature of the surface is determined by the geometric parameters of the surface structures.
School of Physical Science and Technology, Inner Mongolia University, No. 235, DaXue West Road, Huhehot 010021, China; Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing 100101, China.
Fudong
F
Xue
School of Physical Science and Technology, Inner Mongolia University, No. 235, DaXue West Road, Huhehot 010021, China. Electronic address: pyljj@imu.edu.cn.
Junjie
J
Liu
School of Physical Science and Technology, Inner Mongolia University, No. 235, DaXue West Road, Huhehot 010021, China.
Longfang
L
Guo
School of Physical Science and Technology, Inner Mongolia University, No. 235, DaXue West Road, Huhehot 010021, China.
Lirong
L
Zhang
School of Physical Science and Technology, Inner Mongolia University, No. 235, DaXue West Road, Huhehot 010021, China.
Qianzhong
Q
Li
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D018441:Biofilms; D006090:Gram-Negative Bacteria / Q000502:physiology; D006094:Gram-Positive Bacteria / Q000502:physiology; D006430:Hemiptera / Q000382:microbiology* / Q000648:ultrastructure; D054884:Host-Pathogen Interactions; D008954:Models, Biological; D049329:Nanostructures / Q000382:microbiology* / Q000648:ultrastructure; D013499:Surface Properties; D014921:Wings, Animal / Q000382:microbiology* / Q000648:ultrastructure
D000900:Anti-Bacterial Agents
Antibacterial; Catenary; Mechanics model; Nanopatterned surface materials