Endoscopic versus surgical treatment for pancreatic pseudocyst.
OBJECTIVE
To evaluate the effectiveness and safety of endoscopic treatment for pancreatic pseudocyst compared with surgical treatment.


METHODS
PubMed and The Cochrane Library were systematically searched to identify all comparative trials investigating endoscopic versus surgical treatment for pancreatic pseudocyst. Main outcome measures included treatment success rate, adverse events, recurrence rate, length of hospital stay and hospital cost.


RESULTS
Five comparative studies with 255 participants were included in this meta-analysis. The surgical group exhibited a higher treatment success rate than the endoscopic group (OR, 0.43; 95% CI, 0.20-0.95; P = 0.04). However, there was no difference in the rates of adverse events (OR, 0.67; 95% CI, 0.33-1.36; P = 0.27) or recurrence (OR, 1.53; 95% CI, 0.37-6.39; P = 0.56) between the endoscopic and the surgical groups. Evidence from included studies demonstrated that the endoscopic group was associated with shorter length of hospital stay and lower hospital cost compared to the surgical group.


CONCLUSIONS
Endoscopic treatment may be the first-line treatment approach for patients with pancreatic pseudocyst.
Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Xin
X
Zhao
Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Tao
T
Feng
Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Wu
W
Ji
D004322:Drainage / Q000379:methods*; D016145:Endoscopy, Digestive System / Q000379:methods*; D006801:Humans; D010180:Pancreatectomy / Q000379:methods*; D010192:Pancreatic Pseudocyst / Q000601:surgery*; D016896:Treatment Outcome
endoscopy; meta-analysis; pancreatic pseudocyst; surgery; treatment