Adaptive behaviour of Chinese boys with fragile X syndrome.
BACKGROUND
Adaptive behaviour is closely related to quality of life in children with intellectual disability (ID), but little is known about the adaptive behaviour of children with fragile X syndrome (FXS) in China.


METHODS
In boys with FXS, the adaptive behaviours in six domains, including self-dependence, locomotion, work skills, communication, socialisation and self-management, were assessed by the Infants-Junior Middle School Students Social-life Abilities Scale. In addition, we compared the adaptive skills of boys with FXS to those of three control groups of boys, including boys with Down syndrome (DS) and typically developing (TD) boys matched by chronological age (CA) or mental age (MA). The profile of the adaptive behaviour of boys with FXS is discussed in detail.


RESULTS
Compared to boys with DS, boys with FXS obtained lower scores in three domains in adaptive behaviour, including work skills, socialisation and self-management skills; boys with FXS had better scores in self-dependence and locomotion skills than boys matched for MA; as expected, boys with FXS had significantly poorer adaptive skills in all six domains assessed compared to CA boys.


CONCLUSIONS
The development of adaptive skills in boys with FXS was worse than that of boys with DS. The profile of the adaptive behaviour of boys with FXS establishes a basis for the development of targeted interventions to promote social development in this population.
Children's Hospital, Zhejiang University School of Medicine Developmental and Behavioral Pediatrics, Hangzhou, Zhejiang, China.
Z
Z
Zhu
Children's Hospital, Zhejiang University School of Medicine Developmental and Behavioral Pediatrics, Hangzhou, Zhejiang, China.
W
W
Li
Children's Hospital, Zhejiang University School of Medicine Developmental and Behavioral Pediatrics, Hangzhou, Zhejiang, China.
J
J
Zhan
Children's Hospital, Zhejiang University School of Medicine Developmental and Behavioral Pediatrics, Hangzhou, Zhejiang, China.
L
L
Hu
Children's Hospital, Zhejiang University School of Medicine Developmental and Behavioral Pediatrics, Hangzhou, Zhejiang, China.
L
L
Wu
Children's Hospital, Zhejiang University School of Medicine Developmental and Behavioral Pediatrics, Hangzhou, Zhejiang, China.
Z
Z
Zhao
D000223:Adaptation, Psychological / Q000502:physiology*; D002648:Child; D002652:Child Behavior / Q000502:physiology*; D002675:Child, Preschool; D002681:China; D004314:Down Syndrome / Q000503:physiopathology*; D005600:Fragile X Syndrome / Q000503:physiopathology*; D006801:Humans; D008297:Male
China; Down syndrome; adaptive behaviour; boys; children; fragile X syndrome