Characteristics of Intravascular Large B-Cell Lymphoma Limited to the Glomerular Capillaries: A Case Report.
A 65-year-old woman was admitted to our hospital for the evaluation of rapidly progressive renal dysfunction with serum creatinine of 2.7 mg/dl and urinary protein of 1.5 g daily. C-reactive protein (CRP) was 0.1 mg/dl. Kidney-limited intravascular large B-cell lymphoma (IVL) localized to the glomerular capillaries was diagnosed because the intraglomerular cells were positive for CD20 and CD79a, while there was no positivity in the extraglomerular kidney and extrarenal organs. Treatment with rituximab, cyclophosphamide, hydroxydaunomycin, vincristine, and prednisolone was started, and the patient has since been doing well. When IVL is limited to the intraglomerular capillaries, CRP may not be elevated.
Nephrology Center, Toranomon Hospital, Tokyo, Japan ; Department of Nephrology, Ohkubo Hospital, Tokyo, Japan.
Jumpei
J
Hasegawa
Nephrology Center, Toranomon Hospital, Tokyo, Japan.
Junichi
J
Hoshino
Nephrology Center, Toranomon Hospital, Tokyo, Japan.
Tatsuya
T
Suwabe
Nephrology Center, Toranomon Hospital, Tokyo, Japan.
Noriko
N
Hayami
Nephrology Center, Toranomon Hospital, Tokyo, Japan.
Keiichi
K
Sumida
Nephrology Center, Toranomon Hospital, Tokyo, Japan.
Koki
K
Mise
Nephrology Center, Toranomon Hospital, Tokyo, Japan.
Toshiharu
T
Ueno
Nephrology Center, Toranomon Hospital, Tokyo, Japan.
Naoki
N
Sawa
Department of Hematology, Toranomon Hospital, Tokyo, Japan.
Atsushi
A
Wake
Department of Pathology, Toranomon Hospital, Tokyo, Japan.
Kenichi
K
Ohashi
Department of Pathology, Toranomon Hospital, Tokyo, Japan.
Takeshi
T
Fujii
Department of Pathology, Tokyo Women's Medical University, Tokyo, Japan.
Kazuho
K
Honda
Nephrology Center, Toranomon Hospital, Tokyo, Japan ; Department of Okinaka Memorial Institute for Medical Research, Tokyo, Japan.
Kenmei
K
Takaichi
Nephrology Center, Toranomon Hospital, Tokyo, Japan ; Department of Okinaka Memorial Institute for Medical Research, Tokyo, Japan.
Yoshifumi
Y
Ubara
Glomerular capillary; Intravascular large B-cell lymphoma, kidney-limited; Kidney biopsy