Screening for depression and anxiety in patients with storage or voiding dysfunction: A retrospective cohort study predicting outcome of sacral neuromodulation.
It has been reported that somatic treatment in patients with affective symptoms has a higher risk of failure. The aim was to investigate whether affective symptoms could predict the outcome of sacral neuromodulation (SNM) for lower urinary tract symptoms (LUTS).



All patients that underwent a SNM evaluation between 2006 and 2013 and filled out a Hospital Anxiety and Depression Score (HADS) before treatment, were included. Chi-square analysis and bivariate logistic regression were used to assess associations and predictive value.



Eighty-six patients were included, 65 females and 21 males. Most patients, 66, had overactive bladder syndrome (OAB). The remaining 20 patients suffered from non-obstructive urinary retention (NOR). Thirty-nine OAB patients and 17 NOR patients, had a normal total HADS score before treatment. Significantly more patients showed abnormal HADS-D (P = 0.047) and HADS-A (P = 0.015) scores in the OAB group compared to the NOR group. Success of SNM could not be predicted by the HADS score P = 0.464 (after 1 year P = 0.446). Subsequent analysis revealed that an abnormal HADS score was not related to the occurrence of SNM adverse events.



The present study did not reveal a significant relationship between an abnormal HADS score and failure of the SNM test period in a mixed group of OAB and NOR patients. However, differences between OAB and NOR patients concerning affective symptoms were present. It is known that psychological factors play a role in the severity of LUTS, but they may not predict SNM outcome. Neurourol. Urodynam. 35:1011-1016, 2016. © 2015 Wiley Periodicals, Inc.
Department of Urology, Maastricht University Medical Centre (MUMC+), The Netherlands. j.drossaerts@outlook.com.
Jamie
J
Drossaerts
Department of Urology, Maastricht University Medical Centre (MUMC+), The Netherlands.|Pelvic Care Centre Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Desiree
D
Vrijens
Pelvic Care Centre Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.|Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, Maastricht, The Netherlands.
Carsten
C
Leue
Department of Urology, Maastricht University Medical Centre (MUMC+), The Netherlands.
Isabelle
I
Schilders
Department of Urology, Maastricht University Medical Centre (MUMC+), The Netherlands.|Pelvic Care Centre Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Philip
P
Van Kerrebroeck
Department of Urology, Maastricht University Medical Centre (MUMC+), The Netherlands.|Pelvic Care Centre Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Gommert
G
van Koeveringe
D001007:Anxiety / Q000523:psychology*; D015331:Cohort Studies; D003863:Depression / Q000523:psychology*; D004599:Electric Stimulation Therapy / Q000009:adverse effects / Q000379:methods*; D004567:Electrodes, Implanted; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D012189:Retrospective Studies; D012445:Sacrococcygeal Region; D016896:Treatment Outcome; D053201:Urinary Bladder, Overactive / Q000150:complications / Q000523:psychology / Q000628:therapy; D016055:Urinary Retention / Q000150:complications / Q000523:psychology / Q000628:therapy; D014555:Urination Disorders / Q000150:complications / Q000523:psychology* / Q000628:therapy*; D014563:Urodynamics
affective symptoms; anxiety; depression; non-obstructive urinary retention; overactive bladder syndrome; sacral neuromodulation; screening