Factors determining biochemical recurrence in low-risk prostate cancer patients who underwent radical prostatectomy.
OBJECTIVE
This study was conducted to research the factors determining biochemical recurrence (BCR) in low-risk localized prostate cancer patients who underwent radical prostatectomy (RP).


METHODS
We retrospectively analyzed the data of 504 patients who had undergone RP between 2003 and 2013 at our clinic. One hundred and fifty-two patients who underwent RP for low-risk prostate cancer were included in the study.


RESULTS
The mean follow-up period for patients was 58.7 (21-229) months. The mean age of the patients was 63.7±7.2 years (49-79). The mean prostate specific antigen (PSA) value was 5.25±4.22 ng/mL (3.58-9.45). The BCR rate after the operation was 25% (38/152). In the univariate analysis, recurrence determining factors were shown to include extracapsular involvement (ECI) (p=0.004), capsular invasion (CI) (p=0.001), age (p=0.014), and tumor size (p=0.006). However, only CI was found to be significant in multivariate analysis (p=0.001).


CONCLUSIONS
Capsular invasion is an independent risk factor in low-risk prostate cancer patients who underwent RP for BCR.
Clinic of Urology, Tepecik Training and Research Hospital, İzmir, Turkey.
Sıtkı
S
Ün
Clinic of Urology, Tepecik Training and Research Hospital, İzmir, Turkey.
Hakan
H
Türk
Clinic of Urology, Tepecik Training and Research Hospital, İzmir, Turkey.
Osman
O
Koca
Clinic of Urology, Tepecik Training and Research Hospital, İzmir, Turkey.
Rauf Taner
RT
Divrik
Clinic of Urology, Tepecik Training and Research Hospital, İzmir, Turkey.
Ferruh
F
Zorlu
Biochemical recurrence; low-risk; radical prostatectomy