Breast-conserving surgery versus modified radical mastectomy in treatment of early stage breast cancer: A retrospective study of 107 cases.
OBJECTIVE
The aim of this retrospective study was to evaluate the clinical efficacy and prognosis of breast-conserving surgery versus modified radical mastectomy in the treatment of early stage breast cancer.


METHODS
Two hundred and nineteen cases of early stage breast cancer were reviewed and retrospectively included in this study form two hospitals (Quzhou hospital of Zhejiang university and Quzhou Traditional Chinese Hospital). The characteristics of operation procedure such as operation time, intraoperative blood loss and length of hospital stay were compared between the two groups. And the prognosis was recurrence rate was also compared to the two groups.


RESULTS
For the included 219 early breast cancer cases, 107 subjects received the breast-conserving operation, and other 112 cases received the modified radical mastectomy. The operation time, intraoperative blood loss and length of hospital stay were (56.7 ± 14.6) min, (39.2 ± 10.1) ml, (12.1 ± 2.1) day in the breast-conserving group and (95.6 ± 1 3.5) min, (79.5 ± 13.6) ml, (14.8 ± 3.2) day in the modified radical mastectomy group respectively. The operation time, intraoperative blood loss and length of hospital stay were smaller in the breast-conserving group as compared with modified radical mastectomy group with statistical difference (P < 0.05). The overall survival was compared with Kaplan-Meier curve by using log-rank test for the hazard ratio (HR). And the HR was 0.75 with its 95% confidence interval of 0.38-1.48, which indicated that no statistical difference of overall survival was existed between the two groups (P > 0.05).


CONCLUSIONS
The breast-conserving operation was superior to modified radical mastectomy in the aspects of operation time, intraoperative blood loss and length of hospital stay.
Department of Oncology Surgery, Quzhou Hospital of Zhejiang University, Zhejiang, Quzhou 324000, PR China.
Zhenhong
Z
Chen
Ying
Y
Xu
Jingde
J
Shu
Naixi
N
Xu
D000328:Adult; D016063:Blood Loss, Surgical; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007902:Length of Stay; D008207:Lymphatic Metastasis; D015411:Mastectomy, Modified Radical / Q000009:adverse effects / Q000379:methods; D015412:Mastectomy, Segmental / Q000009:adverse effects / Q000379:methods; D008875:Middle Aged; D061646:Operative Time; D012189:Retrospective Studies; D016896:Treatment Outcome; D047368:Tumor Burden