Helicobacter pylori Infection Rates in Patients Undergoing Endoscopy in the Interior of Borneo.
BACKGROUND
Very limited data are available on the Helicobacter pylori infection among the population of interior Borneo. We aimed to investigate the H. pylori infection rate among an endoscoped interior Borneo population and to report the differences between the infected and noninfected patients.


METHODS
We retrospectively analyzed the data of the rapid urease test (RUT) records in Endoscopy Unit Hospital Keningau from January 2009 to May 2014. Student's t-test, chi-square test or Fisher's exact test were used accordingly. Multiple logistic regression analysis was used to identify independent risk factors for H. pylori infection. Birth cohort was analyzed against H. pylori infection rate with chi-square test.


RESULTS
Overall, there were 215 of 774 (27.8%) positive RUTs. Patients with H. pylori infection were younger (47.66 ± 14.93 vs 50.50 ± 15.02 years, p = .019), more likely to be female (OR = 1.54, 95% CI 1.12-2.13, p = .008) and originated from the Pensiangan district (OR = 1.63, 95% CI 1.01-2.64, p = .047). Chinese patients were less likely infected with H. pylori (OR = 0.36, 95% CI 0.16-0.80, p = .013). Birth cohort was significantly associated with H. pylori infection rate (χ(2) (7) = 14.71, p = .040) with an increasing trend of H. pylori infection rate in patients born later (χ(2) (1) = 5.26, p = .022).


CONCLUSIONS
The overall H. pylori infection rate in this population was unexpectedly low. Accordingly, it may be a recent arrival in this community. Gender, age, dietary practice, socioeconomic status, and ethnicity were among the factors associated with H. pylori infection.
Department of Surgery, Hospital Keningau, Sabah, Malaysia.
Feng Yih
FY
Chai
Department of Surgery, Hospital Keningau, Sabah, Malaysia.
Hock Chin
HC
Chong
Department of Surgery, Hospital Keningau, Sabah, Malaysia.
Yew Eng
YE
Tan
Department of Surgery, Hospital Keningau, Sabah, Malaysia.
Sophia Si Ling
SS
Heng
Department of Surgery, Hospital Keningau, Sabah, Malaysia.
Siti Mohd Desa
SM
Asilah
Department of Surgery, Hospital Keningau, Sabah, Malaysia.
Hashim
H
Ridwan
D000328:Adult; D000368:Aged; D001893:Borneo / Q000453:epidemiology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D016481:Helicobacter Infections / Q000453:epidemiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D014510:Urease / Q000032:analysis
D014510:Urease
Borneo; Helicobacter pylori; Malaysia; Sabah; epidemiology