Pinosylvin Inhibits TRPA1-Induced Calcium Influx In Vitro and TRPA1-Mediated Acute Paw Inflammation In Vivo.
The Immunopharmacology Research Group, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland.
Lauri J
LJ
Moilanen
The Immunopharmacology Research Group, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland.
Mari
M
Hämäläinen
Department of Respiratory Medicine, University of Tampere School of Medicine and Allergy Centre, Tampere University Hospital, Tampere, Finland.
Lauri
L
Lehtimäki
The Immunopharmacology Research Group, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland.
Riina M
RM
Nieminen
Laboratory of Cellular Pharmacology, School of Pharmacy, Aichi-Gakuin University, Nagoya, Japan.
Katsuhiko
K
Muraki
The Immunopharmacology Research Group, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland.
Eeva
E
Moilanen
D000208:Acute Disease; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism*; D057809:HEK293 Cells; D006801:Humans; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy* / Q000235:genetics; D020128:Inhibitory Concentration 50; D017879:Isothiocyanates / Q000633:toxicity; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009419:Nerve Tissue Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013267:Stilbenes / Q000494:pharmacology*; D000074025:TRPA1 Cation Channel; D050051:Transient Receptor Potential Channels / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000094162:Phytoalexins
D002118:Calcium; D015220:Calcium Channels; D017879:Isothiocyanates; D009419:Nerve Tissue Proteins; D013267:Stilbenes; D000074025:TRPA1 Cation Channel; D050051:Transient Receptor Potential Channels; C473350:TRPA1 protein, human; C475685:Trpa1 protein, mouse; C049032:pinosylvin; D000094162:Phytoalexins; C004471:allyl isothiocyanate