Thymoma-Associated Graft-Versus-Host-Like Disease With Skin Manifestations Improved by Complete Resection of Thymoma.
A 69-year-old woman with refractory skin eruptions, which had first appeared 3 years previously, was examined, and an anterior mediastinal tumor was detected. The tumor was resected, and a diagnosis of type B2 thymoma, stage III disease (according to the World Health Organization classification), was made. Retrospectively, histologic findings of the skin before the operation were consistent with graft-versus-host disease. The final diagnosis of her skin lesions was thymoma-associated graft-versus-host-like disease. The skin lesions improved gradually during the 1-month period after resection with only a topical steroid, and further improvement was seen at 3 months.
Department of Thoracic Surgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan. Electronic address: mmotoish@kyotolan.hosp.go.jp.
Makoto
M
Motoishi
Department of Thoracic Surgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Keigo
K
Okamoto
Department of Thoracic Surgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Ryosuke
R
Kaku
Department of Thoracic Surgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Satoru
S
Sawai
Department of Thoracic Surgery, Shiga University of Medical Science, Shiga, Japan.
Jun
J
Hanaoka
D000368:Aged; D005076:Exanthema / Q000209:etiology*; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology*; D006801:Humans; D012074:Remission Induction; D013945:Thymoma / Q000150:complications* / Q000601:surgery*; D013953:Thymus Neoplasms / Q000150:complications* / Q000601:surgery*