Copper/Manganese Cocatalyzed Oxidative Coupling of Vinylarenes with Ketones.
A novel copper/manganese cocatalyzed direct oxidative coupling of terminal vinylarenes with ketones via C(sp(3))-H bond functionalization following C-C bond formation has been developed using tert-butyl hydroperoxide as the radical initiator. Various ketones underwent a free-radical addition of terminal vinylarenes to give the corresponding 1,4-dicarbonyl products with excellent regioselectivity and efficiency through one step. A possible reaction mechanism has been proposed.
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
Xing-Wang
XW
Lan
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
Nai-Xing
NX
Wang
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
Wei
W
Zhang
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
Jia-Long
JL
Wen
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
Cui-Bing
CB
Bai
Department of Chemistry, William Paterson University of New Jersey , 300 Pompton Road, Wayne, New Jersey 07470, United States.
Yalan
Y
Xing
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
Yi-He
YH
Li