Pharmacological manipulation of AID.
Institut de Recherches Cliniques de Montréal, Montréal, QC, Canada.|Department of Medicine, McGill University, Montreal, QC, Canada.
Stephen P
SP
Methot
Institut de Recherches Cliniques de Montréal, Montréal, QC, Canada.|Department of Medicine, McGill University, Montreal, QC, Canada.|Department of Medicine, Université de Montréal, Montréal, QC, Canada.
Javier M
JM
Di Noia
D003564:Cytidine Deaminase / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism; D004247:DNA / Q000737:chemistry; D015977:Eukaryotic Initiation Factor-1 / Q000037:antagonists & inhibitors / Q000378:metabolism; D018841:HSP90 Heat-Shock Proteins / Q000378:metabolism; D006801:Humans; D007107:Immune System; D028884:Karyopherins / Q000378:metabolism; D009154:Mutation; D011485:Protein Binding; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D000097606:Exportin 1 Protein; D000098830:AICDA (Activation-Induced Cytidine Deaminase)
D003564:Cytidine Deaminase; D004247:DNA; D015977:Eukaryotic Initiation Factor-1; D018841:HSP90 Heat-Shock Proteins; D028884:Karyopherins; D018160:Receptors, Cytoplasmic and Nuclear; D000097606:Exportin 1 Protein; D000098830:AICDA (Activation-Induced Cytidine Deaminase); C026022:eukaryotic peptide initiation factor-1A
HSP90; activation induced deaminase; antibody diversification; eEF1A; oncogenic activity