Oral mucosal involvement and petechial lesions: a SDRIFE case with unusual findings.
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a type IV hypersensitivity reaction characterized by a symmetrical erythematous rash in the gluteal and intertriginous areas. SDRIFE was previously considered to be the same presentation as Baboon Syndrome, however, has been suggested to be a different entity in the recent publications. The lesions are generally maculopapular and there is no mucosal involvement. To date, no case with petechial findings and mucosal involvement has been reported in the literature. The present study reports a SDRIFE case with a symmetrical erythematous petechial rash and oral mucosal involvement after taking oral amoxicillin.
a Department of Dermatology , School of Medicine, Istanbul Medeniyet University , Istanbul , Turkey .
Ayse Serap
AS
Karadag
b Department of Dermatology, Faculty of Medicine, Goztepe Research and Training Hospital , Istanbul Medeniyet University , Istanbul , Turkey .
Emin
E
Ozlu
b Department of Dermatology, Faculty of Medicine, Goztepe Research and Training Hospital , Istanbul Medeniyet University , Istanbul , Turkey .|c Department of Dermatology, Faculty of Medicine , Yuzuncu Yil University , Van , Turkey .
Necmettin
N
Akdeniz
d Department of Dermatology Goztepe Research and Training Hospital , Istanbul Medeniyet University , Istanbul , Turkey .
Tugba Kevser
TK
Uzuncakmak
e Department of Dermatology , Goztepe Training Hospital, Medeniyet University , Istanbul , Turkey , and.
Zafer
Z
Turkoglu
d Department of Dermatology Goztepe Research and Training Hospital , Istanbul Medeniyet University , Istanbul , Turkey .
Seyma
S
Ozkanli
f Department of Pathology , SB Goztepe Training and Research Hospital, Istanbul Medeniyet University , Istanbul , Turkey.
Ebru
E
Zemheri
D000328:Adult; D000658:Amoxicillin / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005076:Exanthema / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology*; D011693:Purpura / Q000139:chemically induced* / Q000473:pathology
D000900:Anti-Bacterial Agents; D000658:Amoxicillin
Drug eruption; SDRIFE; drug toxicity