Usefulness of Adjunctive Fecal Calprotectin and Serum Procalcitonin in Individuals Positive for Clostridium difficile Toxin Gene by PCR Assay.
In 54/64 subjects with nosocomial diarrhea, fecal calprotectin levels correlated with the results of stool samples tested for Clostridium difficile toxin gene by PCR. Fecal calprotectin levels can be used as an adjunctive measure to PCR to support the diagnosis of C. difficile infection.
Division of Infectious Diseases, McGill University Health Centre, Montreal, Quebec, Canada kristin.popiel@mail.mcgill.ca.
Kristin Y
KY
Popiel
Division of Infectious Diseases, Jewish General Hospital, Montreal, Quebec, Canada.
Romina
R
Gheorghe
Division of Infectious Diseases, Jewish General Hospital, Montreal, Quebec, Canada.
Jennifer
J
Eastmond
Division of Infectious Diseases, Jewish General Hospital, Montreal, Quebec, Canada.
Mark A
MA
Miller
D001427:Bacterial Toxins / Q000235:genetics*; D001681:Biological Assay; D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D016360:Clostridioides difficile / Q000235:genetics* / Q000472:pathogenicity; D003404:Creatinine / Q000097:blood; D003428:Cross Infection; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis* / Q000382:microbiology; D004768:Enterotoxins / Q000235:genetics*; D005243:Feces / Q000737:chemistry / Q000382:microbiology; D005260:Female; D006801:Humans; D039841:Leukocyte L1 Antigen Complex / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011446:Prospective Studies; D011498:Protein Precursors / Q000097:blood*; D012680:Sensitivity and Specificity; D012709:Serum Albumin / Q000032:analysis
D001427:Bacterial Toxins; C000606589:CALCA protein, human; D004768:Enterotoxins; D039841:Leukocyte L1 Antigen Complex; D011498:Protein Precursors; D012709:Serum Albumin; D002116:Calcitonin; D003404:Creatinine; D015740:Calcitonin Gene-Related Peptide