A simple synthesis of nitrogen doped porous graphitic carbon: Electrochemical determination of paracetamol in presence of ascorbic acid and p-aminophenol.
Graphite paste electrode modified with nitrogen doped porous carbon (NDPC) is used for the detections of paracetamol (PCM), ascorbic acid (AA) and p-aminophenol (PAP) at relatively low concentration. NDPC is synthesized by direct carbonization of Zn(OAc)2 incorporated melamine-formaldehyde resin microsphere. The NDPC shows small pore diameters centered at 3.14 nm and 8.12 nm and has a pseudo graphitic structure with reasonable porous matrix. The lower limit of detections (S/N = 3) for PCM, AA, and PAP are found to be 30 nM, 720 nM and 10 nM respectively. Under optimized experimental condition, the linear ranges of determination for PCM and AA are 1-400 μM, 10-2700 μM respectively in mixture. Similarly for PCM and PAP mixture, the linear ranges of determination are found to be 1-90 μM. It is also used for the analysis of urine and pharmaceutical products with better sensitivity.
Department of Instrumentation and Electronics Engineering, Jadavpur Universiy Salt Lake Campus, Kolkata 700098, India.
Sudip
S
Biswas
Department of Instrumentation and Electronics Engineering, Jadavpur Universiy Salt Lake Campus, Kolkata 700098, India.
Dipanjan
D
Chakraborty
Department of Instrumentation and Electronics Engineering, Jadavpur Universiy Salt Lake Campus, Kolkata 700098, India.
Rashmita
R
Das
Department of Instrumentation and Electronics Engineering, Jadavpur Universiy Salt Lake Campus, Kolkata 700098, India.
Rajib
R
Bandyopadhyay
Department of Basic Science, MCKV Institute of Engineering, Liluah, West Bengal 711204, India. Electronic address: pramanik1946@gmail.com.
Panchanan
P
Pramanik
D000082:Acetaminophen / Q000032:analysis*; D000627:Aminophenols / Q000737:chemistry*; D001205:Ascorbic Acid / Q000737:chemistry*; D002384:Catalysis; D055664:Electrochemical Techniques; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry*; D010084:Oxidation-Reduction; D016062:Porosity; D015203:Reproducibility of Results; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman
D000627:Aminophenols; D000082:Acetaminophen; D006108:Graphite; D009584:Nitrogen; D001205:Ascorbic Acid; C026729:4-aminophenol
Electrochemical determination; Melamine-formaldehyde resin; Nitrogen doped porous carbon; Paracetamol; p-Aminophenol