Chemical Modification of Boron-Doped Diamond Electrodes for Applications to Biosensors and Biosensing.
Boron-doped diamond (BDD) is a prospective electrode material that possesses many exceptional properties including wide potential window, low noise, low and stable background current, chemical and mechanical stability, good biocompatibility, and last but not least exceptional resistance to passivation. These characteristics extend its usability in various areas of electrochemistry as evidenced by increasing number of published articles over the past two decades. The idea of chemically modifying BDD electrodes with molecular species attached to the surface for the purpose of creating a rational design has found promising applications in the past few years. BDD electrodes have appeared to be excellent substrate materials for various chemical modifications and subsequent application to biosensors and biosensing. Hence, this article presents modification strategies that have extended applications of BDD electrodes in electroanalytical chemistry. Different methods and steps of surface modification of this electrode material for biosensing and construction of biosensors are discussed.
a Institute of Analytical Chemistry, Slovak University of Technology in Bratislava , Bratislava , Slovakia.
Jana
J
Svítková
a Institute of Analytical Chemistry, Slovak University of Technology in Bratislava , Bratislava , Slovakia.
Teodora
T
Ignat
a Institute of Analytical Chemistry, Slovak University of Technology in Bratislava , Bratislava , Slovakia.
Ľubomír
Ľ
Švorc
a Institute of Analytical Chemistry, Slovak University of Technology in Bratislava , Bratislava , Slovakia.
Ján
J
Labuda
b UNESCO Laboratory of Environmental Electrochemistry , Department of Analytical Chemistry, Charles University in Prague , Prague , Czech Republic.
Jiří
J
Barek
D015374:Biosensing Techniques / Q000295:instrumentation*; D001895:Boron / Q000737:chemistry*; D018130:Diamond / Q000737:chemistry*; D004566:Electrodes
D018130:Diamond; D001895:Boron
Biosensing; biosensor; boron-doped diamond electrode; chemically modified electrode