Reversible morphology transitions of supramolecular polymer self-assemblies for switch-controlled drug release.
A novel method for switch-controlled drug release was developed through the reversible morphology transitions of supramolecular branched copolymer self-assemblies. The reversible transitions from vesicles to nanoparticles were successfully achieved by alternating UV and visible light irradiation to obtain morphology-controlled drug release in a switch mode.
The Key Laboratory of Space Applied Physics and Chemistry, Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Science, Northwestern Polytechnical University, Xi'an, 710072, P. R. China. happytw_3000@nwpu.edu.cn xfand@126.com.
Haitao
H
Zhang
Xiaodong
X
Fan
Rongtian
R
Suo
Hui
H
Li
Zhen
Z
Yang
Wanbin
W
Zhang
Yang
Y
Bai
Hao
H
Yao
Wei
W
Tian
D004318:Doxycycline / Q000032:analysis* / Q000737:chemistry*; D065546:Drug Liberation; D008027:Light; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry*; D013499:Surface Properties; D014466:Ultraviolet Rays
D011108:Polymers; D004318:Doxycycline