Motor System Reorganization After Stroke: Stimulating and Training Toward Perfection.
Stroke instigates regenerative responses that reorganize connectivity patterns among surviving neurons. The new connectivity patterns can be suboptimal for behavioral function. This review summarizes current knowledge on post-stroke motor system reorganization and emerging strategies for shaping it with manipulations of behavior and cortical activity to improve functional outcome.
Psychology Department, Neuroscience Institute, University of Texas at Austin, Austin, Texas; and tj@austin.utexas.edu.
Theresa A
TA
Jones
Neurosciences Department, and Health Sciences & Research Department, Colleges of Medicine & Health Professions, Medical University of South Carolina, Charleston, South Carolina.
DeAnna L
DL
Adkins
D000818:Animals; D003131:Combined Modality Therapy; D004599:Electric Stimulation Therapy / Q000379:methods*; D026241:Exercise Movement Techniques / Q000379:methods*; D006801:Humans; D009043:Motor Activity; D009044:Motor Cortex / Q000503:physiopathology*; D009434:Neural Pathways / Q000503:physiopathology; D009473:Neuronal Plasticity; D020127:Recovery of Function; D012149:Restraint, Physical; D020521:Stroke / Q000503:physiopathology / Q000523:psychology; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome