[Imaging techniques and pain].
Over the last 15 years, functional brain imaging techniques have provided critical insights into cortical, subcortical and even spinal mechanisms involved in pain perception and pain modulation in humans. The pivotal contribution of brain imaging studies conducted in Germany have thereby been internationally acknowledged. One of the key challenges for the next decade is to shift the focus from studies in healthy volunteers to different clinical populations suffering from chronic pain to characterize CNS mechanisms, as well as neurobiological predictors and resilience factors of pain chronification. Ultimately, the knowledge gained by this work may help identify individual or syndrome-specific CNS changes as biomarkers to make therapeutic decisions.
Klinik für Neurologie und Neurophysiologie, Klinikum Fürth, Fürth, Deutschland.
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Maihöfner
Klinik für Neurologie, Universitätsklinikum Essen, Hufelandstr. 55, 45147, Essen, Deutschland. ulrike.bingel@uk-essen.de.
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Bingel
D001931:Brain Mapping; D002540:Cerebral Cortex / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D009415:Nerve Net / Q000000981:diagnostic imaging / Q000503:physiopathology; D010146:Pain / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D059408:Pain Management / Q000379:methods; D058748:Pain Perception / Q000502:physiology; D049268:Positron-Emission Tomography; D013116:Spinal Cord / Q000000981:diagnostic imaging* / Q000503:physiopathology*
Functional imaging; Germany; Magnetic resonance imaging; Pain perception; Positron emission tomography