A recognition-mediated reaction drives amplification within a dynamic library.
A single, appropriately designed, recognition event targets and transforms one of two reactive members of an exchanging pool of compounds through a recognition-mediated irreversible cycloaddition reaction, altering dramatically the final composition and kinetic behaviour of the dynamic library.
School of Chemistry and EaStCHEM, University of St Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK. d.philp@st-andrews.ac.uk.
Jan W
JW
Sadownik
Douglas
D
Philp