Factors affecting mortality in patients with organophosphate poisoning.
OBJECTIVE
To investigate the relationship between clinical and demographic characteristics and mortality in patients with organophosphate poisoning.


METHODS
The retrospective study was conducted at Dicle University,Diyarbakir,Turkey, and comprised data of patients who presented with organophosphate poisoning between April 2004 and April 2013. The records were assessed in two groups, with Group 1 having data related to recovery, and Group 2 having data related to mortality. SPSS 16 was used for statistical analysis.


RESULTS
Of the 296 patients, 219(74%) were women. Mortality was the outcome in 41(13.9%) cases. In Group 2, mean age, marital status, rural origin, presence of psychiatric disease, being illiterate, presence of nicotinic symptoms, and late admission were significantly higher than Group 1 (p<0.05 each). Logistic regression analysis indicated bradycardia as the most prominent independent predictor of mortality (p<0.001). Other independent predictors were age, glucose level, lactate dehydrogenase, coma and acidosis (p<0.05 each).


CONCLUSIONS
Independent predictors of mortality in patients with organophosphate poisoning as bradycardia, age, glucose, lactate dehydrogenase level and acidosis.
Department of Emergency Medicine, Turkey.
Ercan
E
Gündüz
Department of Emergency Medicine, Turkey.
Recep
R
Dursun
Department of Emergency Medicine, Turkey.
Mustafa
M
Icer
Department of Emergency Medicine, Turkey.
Yilmaz
Y
Zengin
Department of Emergency Medicine, Turkey.
Mehmet Nezir
MN
Güllü
Department of Emergency Medicine, Turkey.
Hasan Mansur
HM
Durgun
Department of Pharmacology, Dicle University, Diyarbakir, Turkey.
Osman
O
Gokalp
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D062025:Organophosphate Poisoning / Q000401:mortality*; D012189:Retrospective Studies; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology
Poisoning, Organophosphate, Mortality.