The Malleable Implant Salvage Technique: Infection Outcomes after Mulcahy Salvage Procedure and Replacement of Infected Inflatable Penile Prosthesis with Malleable Prosthesis.
OBJECTIVE
Since its introduction in 1996 Mulcahy salvage has significantly improved outcomes for the removal and replacement of infected inflatable penile prostheses. Long-term followup data of Mulcahy salvage show an infection-free rate of 82%. A multicenter retrospective analysis of the malleable implant salvage technique was conducted to assess infection outcomes and the feasibility of conversion from malleable device back to inflatable penile prosthesis.


METHODS
This is a retrospective, institutional review board exempt, multi-institution study of 58 patients who underwent Mulcahy salvage with inflatable penile prosthesis removal and replacement with malleable prosthesis. Patient operative notes and charts were extensively reviewed to compile study data.


RESULTS
Between 2002 and 2014 a total of 58 patients underwent infected inflatable penile prosthesis removal and replacement with a malleable prosthesis via Mulcahy salvage. Of these patients 54 (93%) have remained infection-free postoperatively. Average patient age was 56.4 years and average operative time was 148 minutes. Postoperative followup (as of May 2015) ranged from 1 month to 84 months. Of the 54 patients 37 retained the malleable prosthesis and 17 (31%) subsequently underwent replacement with an inflatable penile prosthesis. This occurred on average 6.7 months after Mulcahy salvage. Four patients had persistent infection after Mulcahy salvage with the malleable prosthesis and underwent explantation.


CONCLUSIONS
This retrospective analysis of Mulcahy salvage procedure and replacement of inflatable penile prosthesis with malleable prosthesis shows a high infection-free rate. Additionally, 17 of the 54 patients who remained infection-free were able to successfully undergo subsequent removal of the malleable prosthesis and replacement with an inflatable penile prosthesis. Further prospective studies are needed to compare salvage with malleable vs inflatable penile prosthesis.
Boston University Medical Center, Boston, Massachusetts. Electronic address: martin.s.gross@gmail.com.
Martin S
MS
Gross
Boston University Medical Center, Boston, Massachusetts.
Elizabeth A
EA
Phillips
Boston University Medical Center, Boston, Massachusetts.
Alejandra
A
Balen
Advanced Urological Care, New York, New York.
J Francois
JF
Eid
USF Morsani College of Medicine, Tampa.
Christopher
C
Yang
USF Morsani College of Medicine, Tampa.
Ross
R
Simon
USF Morsani College of Medicine, Tampa.
Daniel
D
Martinez
USF Morsani College of Medicine, Tampa.
Rafael
R
Carrion
Perito Urology, Coral Gables, Florida.
Paul
P
Perito
Rush Medical College, Chicago, Illinois.
Laurence
L
Levine
Urology Associates of North Texas, Arlington, Texas.
Jason
J
Greenfield
Boston University Medical Center, Boston, Massachusetts.
Ricardo
R
Munarriz
D000328:Adult; D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D015917:Penile Prosthesis / Q000009:adverse effects*; D011474:Prosthesis Design; D019919:Prosthesis Implantation; D016459:Prosthesis-Related Infections / Q000209:etiology* / Q000601:surgery*; D012189:Retrospective Studies
erectile dysfunction; infection; penile prosthesis; salvage therapy