Practical Synthesis of p- and o-Amino- and Methoxyphenolic Anthraquinones.
New versatile and selective methods for the syntheses of substituted amino- and methoxyphenolic anthraquinones (I-IV) based on fusion of cyanophthalides (V) and semiquinone aminals (VI, VII) under basic conditions are described.
Department of Chemistry, BioScience Research Collaborative, Rice University, 6100 Main Street, Houston, TX 77005 (USA). kcn@rice.edu.
K C
KC
Nicolaou
Department of Chemistry, BioScience Research Collaborative, Rice University, 6100 Main Street, Houston, TX 77005 (USA).
Min
M
Lu
Department of Chemistry, BioScience Research Collaborative, Rice University, 6100 Main Street, Houston, TX 77005 (USA).
Pengxi
P
Chen
Department of Chemistry, BioScience Research Collaborative, Rice University, 6100 Main Street, Houston, TX 77005 (USA).
Akshay A
AA
Shah
D000586:Amination; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D000880:Anthraquinones / Q000138:chemical synthesis* / Q000737:chemistry; D001572:Benzofurans / Q000138:chemical synthesis / Q000737:chemistry; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry
D000588:Amines; D000880:Anthraquinones; D001572:Benzofurans; D010636:Phenols; C082022:phthalide
3-cyanophthalides; semiquinone aminals; substituted anthraquinones