Rapidly Progressive Interstitial Lung Disease Associated with Dermatomyositis Treated with Combination of Immunosuppressive Therapy, Direct Hemoperfusion with a Polymyxin B Immobilized Fiber Column and Intravenous Immunoglobulin.
Rapidly progressive interstitial lung disease (ILD) is associated with dermatomyositis (DM) and has a high mortality rate even with immunosuppressive agents. For such cases, there is no evidence on the combined effect of direct hemoperfusion with a Polymyxin B immobilized fiber column and intravenous immunoglobulin. We herein report a case of 61-year-old woman who presented with respiratory failure. She showed ILD associated with DM which did not improve with immunosuppressive agents, but was improved with the addition of both direct hemoperfusion with a Polymyxin B immobilized fiber column and intravenous immunoglobulin.
Department of Pulmonary Medicine, Kameda Medical Center, Japan.
Motohisa
M
Takai
Naoko
N
Katsurada
Tamao
T
Nakashita
Masafumi
M
Misawa
Takahiro
T
Mochizuki
Norihiro
N
Kaneko
Shinji
S
Motojima
Masahiro
M
Aoshima
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003882:Dermatomyositis / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D018450:Disease Progression; D005260:Female; D006464:Hemoperfusion / Q000379:methods; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage*; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D011112:Polymyxin B / Q000008:administration & dosage*; D012131:Respiratory Insufficiency / Q000209:etiology; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; D011112:Polymyxin B