title: Gene Co-Expression Analysis Inferring the Crosstalk of Ethylene and Gibberellin in Modulating the Transcriptional Acclimation of Cassava Root Growth in Different Seasons.
abstract: Cassava is a crop of hope for the 21st century. Great advantages of cassava over other crops are not only the capacity of carbohydrates, but it is also an easily grown crop with fast development. As a plant which is highly tolerant to a poor environment, cassava has been believed to own an effective acclimation process, an intelligent mechanism behind its survival and sustainability in a wide range of climates. Herein, we aimed to investigate the transcriptional regulation underlying the adaptive development of a cassava root to different seasonal cultivation climates. Gene co-expression analysis suggests that AP2-EREBP transcription factor (ERF1) orthologue (D142) played a pivotal role in regulating the cellular response to exposing to wet and dry seasons. The ERF shows crosstalk with gibberellin, via ent-Kaurene synthase (D106), in the transcriptional regulatory network that was proposed to modulate the downstream regulatory system through a distinct signaling mechanism. While sulfur assimilation is likely to be a signaling regulation for dry crop growth response, calmodulin-binding protein is responsible for regulation in the wet crop. With our initiative study, we hope that our findings will pave the way towards sustainability of cassava production under various kinds of stress considering the future global climate change.
authors.affiliation: Bioinformatics and Systems Biology Program, School of Bioresources and Technology, King Mongkut's University of Technology Thonburi, Thakham, Bangkhunthian, Bangkok, Thailand; Systems Biology and Bioinformatics Research Group, Pilot Plant Development and Training Institute, King Mongkut's University of Technology Thonburi, Thakham, Bangkhunthian, Bangkok, Thailand.
authors.forename: Treenut
authors.initials: T
authors.lastname: Saithong
authors.affiliation: Bioinformatics and Systems Biology Program, School of Bioresources and Technology, King Mongkut's University of Technology Thonburi, Thakham, Bangkhunthian, Bangkok, Thailand.
authors.forename: Samorn
authors.initials: S
authors.lastname: Saerue
authors.affiliation: Bioinformatics and Systems Biology Program, School of Bioresources and Technology, King Mongkut's University of Technology Thonburi, Thakham, Bangkhunthian, Bangkok, Thailand; Systems Biology and Bioinformatics Research Group, Pilot Plant Development and Training Institute, King Mongkut's University of Technology Thonburi, Thakham, Bangkhunthian, Bangkok, Thailand.
authors.forename: Saowalak
authors.initials: S
authors.lastname: Kalapanulak
authors.affiliation: Center for Cassava Molecular Biotechnology, Faculty of Science, Mahidol University, Thungphayathai, Ratchathewi, Bangkok, Thailand; Department of Biotechnology, Faculty of Science, Mahidol University, Thungphayathai, Ratchathewi, Bangkok, Thailand.
authors.forename: Punchapat
authors.initials: P
authors.lastname: Sojikul
authors.affiliation: Center for Cassava Molecular Biotechnology, Faculty of Science, Mahidol University, Thungphayathai, Ratchathewi, Bangkok, Thailand; Department of Biotechnology, Faculty of Science, Mahidol University, Thungphayathai, Ratchathewi, Bangkok, Thailand.
authors.forename: Jarunya
authors.initials: J
authors.lastname: Narangajavana
authors.affiliation: Systems Biology and Bioinformatics Research Group, Pilot Plant Development and Training Institute, King Mongkut's University of Technology Thonburi, Thakham, Bangkhunthian, Bangkok, Thailand; Department of Chemical Engineering, Faculty of Engineering, King Mongkut's University of Technology Thonburi, Bangkok, Thungkhru, Bangmod, Bangkok, Thailand.
authors.forename: Sakarindr
authors.initials: S
authors.lastname: Bhumiratana
mesh_terms: D000064:Acclimatization / Q000235:genetics*; D002980:Climate; D005030:Ethylenes / Q000378:metabolism*; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D005875:Gibberellins / Q000378:metabolism*; D002365:Manihot / Q000235:genetics / Q000254:growth & development / Q000502:physiology*; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D018517:Plant Roots / Q000235:genetics / Q000254:growth & development / Q000502:physiology; D011401:Promoter Regions, Genetic; D012621:Seasons; D015398:Signal Transduction; D013312:Stress, Physiological; D014867:Water / Q000378:metabolism
chemical_list: D005030:Ethylenes; D005875:Gibberellins; D010940:Plant Proteins; D014867:Water; C036216:ethylene