title: Melanoma Drug Works in Other Tumors.
abstract: In a phase II basket trial, vemurafenib, an enzyme inhibitor prescribed for certain BRAF V600-mutant melanomas, proved effective in some nonmelanoma cancers that also carried a BRAF V600 mutation.
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy*; D005260:Female; D015614:Histiocytosis / Q000188:drug therapy*; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D008297:Male; D009154:Mutation; D009369:Neoplasms / Q000188:drug therapy*; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics*; D013449:Sulfonamides / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D013449:Sulfonamides; D048493:Proto-Oncogene Proteins B-raf