title: Trialkyl Methanetricarboxylate as Dialkyl Malonate Surrogate in Copper-Catalyzed Enantioselective Propargylic Substitution.
abstract: The first copper-catalyzed enantioselective propargylation of trialkyl methantricarboxylate with propargylic alcohol derivatives was developed. The tricarboxylate unit in the obtained adducts could be easily transformed into a malonate moiety by treating with in situ generated NaOEt in excellent yield without racemization.
authors.affiliation: Department of Chemistry, College of Sciences, Shanghai University 99 Shangda Road, Shanghai 200444, China.
authors.forename: Guanxin
authors.initials: G
authors.lastname: Huang
authors.affiliation: Department of Chemistry, College of Sciences, Shanghai University 99 Shangda Road, Shanghai 200444, China.
authors.forename: Cang
authors.initials: C
authors.lastname: Cheng
authors.affiliation: Department of Chemistry, College of Sciences, Shanghai University 99 Shangda Road, Shanghai 200444, China.
authors.forename: Luo
authors.initials: L
authors.lastname: Ge
authors.affiliation: Department of Chemistry, College of Sciences, Shanghai University 99 Shangda Road, Shanghai 200444, China.
authors.forename: Beibei
authors.initials: B
authors.lastname: Guo
authors.affiliation: Department of Chemistry, College of Sciences, Shanghai University 99 Shangda Road, Shanghai 200444, China.
authors.forename: Long
authors.initials: L
authors.lastname: Zhao
authors.affiliation: Department of Chemistry, College of Sciences, Shanghai University 99 Shangda Road, Shanghai 200444, China.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Wu