title: Mammographic findings after reshaping with autoprosthesis in women undergoing contralateral breast reconstruction and mastectomy.
abstract: OBJECTIVE
  Breast reduction and mastopexy combined with inferior dermo-lipo-glandular flap (autoprosthesis) gives good breast shape, long-term projection, and upper pole fullness. We assess the impact on breast oncologic surveillance compared to other techniques.
  
  
  METHODS
  A total of 105 patients who underwent mastectomy and reconstruction were divided into 3 groups of 35 patients each: groups 1 and 2 include patients with contralateral breast symmetrization performed with and without autoprosthesis technique, respectively. Group 3 is a control group without contralateral breast reshaping. On mammography, edema, skin thickening, architectural distortion, and calcifications were recorded, as well as further diagnostic examinations, biopsies, and surgical treatments required.
  
  
  RESULTS
  Statistically significant differences (p&lt;0.001) in the first follow-up mammography between groups 1 and 2 were stromal edema (6% vs 51%) and architectural distortion (74% vs 63%). The latest findings meant architectural distortion also have significant difference (p&lt;0.001) in the last mammography (79% vs 66%). Microcalcification has statistically significant difference (p&lt;0.001) in the latest postsurgical mammography, increased in group 1. Skin thickening had a similar course in either group. Mammography follow-up was not impaired in most cases notwithstanding the parenchyma distortion as compared with mammography after breast-conserving surgery. Four core biopsies were performed in both groups: 3 new breast cancers and 1 benign epithelial hyperplasia were found.
  
  
  CONCLUSIONS
  No difficulties were found impairing mammographic evaluation in patients treated with autoprosthesis as compared to other techniques.
authors.affiliation: Department of Diagnostic Radiology 1, Breast Imaging, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Scaperrotta
authors.affiliation: Scuola di Specializzazione di Radiodiagnostica, Università degli Studi di Milano, Milan - Italy.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Capalbo
authors.affiliation: Department of Diagnostic Radiology 1, Breast Imaging, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Ferranti
authors.affiliation: Department of Anaesthesiological, Surgical and Emergency Sciences, Second University of Napoli, Napoli - Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Falco
authors.affiliation: Department of Plastic and Reconstructive Surgery, Fondazione IRCCS Istituto Nazionale Tumori, Milan - Italy.
authors.forename: Maurizio B
authors.initials: MB
authors.lastname: Nava
authors.affiliation: Servizio di Radiologia, IRCCS Policlinico San Donato, San Donato Milanese, Milan - Italy.
authors.forename: Gianni
authors.initials: G
authors.lastname: Di Leo
authors.affiliation: Department of Diagnostic Radiology 1, Breast Imaging, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.
authors.forename: Monica
authors.initials: M
authors.lastname: Marchesini
authors.affiliation: Department of Diagnostic Radiology 1, Breast Imaging, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Suman
authors.affiliation: Department of Diagnostic Radiology 1, Breast Imaging, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Panizza
mesh_terms: D000328:Adult; D000368:Aged; D062005:Biopsy, Large-Core Needle; D001940:Breast / Q000473:pathology* / Q000601:surgery*; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D002114:Calcinosis / Q000209:etiology; D003560:Cysts / Q000209:etiology; D004487:Edema / Q000209:etiology; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects / Q000379:methods*; D008327:Mammography; D015411:Mastectomy, Modified Radical; D008875:Middle Aged; D012189:Retrospective Studies; D018401:Sample Size; D012867:Skin / Q000473:pathology; D013524:Surgical Flaps; D014182:Transplantation, Autologous; D055815:Young Adult