title: [Effect of pharmacotherapy on course of postoperative period after endovenous thermal ablation].
abstract: The authors assessed the effect of a micronized purified flavonoid fraction (MPFF) on the course of the postoperative period after endovenous thermal ablation (EVTA). The patients of the Study Group matching by the main studied parameters to the Control Group patients were given the MPFF according to the suggested regimen for 7 days. The obtained results were analysed by means of questionnaires (CIVIQ, VCSS, VAS) and ultrasound angioscanning. The obtained findings were statistically processed by means of the program Statistica 6.0 and reliability of the results was assessed with the help of the Student t-test. Patients of the both groups showed complete stable obliteration of the target veins. No statistically significant differences of the items of the questionnaires CIVIQ and VCSS at the beginning of the study and at the last examination were revealed, differences were noted on days 2-14 after EVTA and were not statistically significant (p>0.05). Phlebotrophic therapy in the postoperative period after EVTA helps to decrease phlebitic alterations in the coagulated vein, to improve motor activity and mental psychoemotional state of the patients.
authors.affiliation: National Medical Surgical Centre named after N.I. Pirogov, Moscow, Russia.
authors.forename: Yu M
authors.initials: YM
authors.lastname: Stoiko
authors.affiliation: National Medical Surgical Centre named after N.I. Pirogov, Moscow, Russia.
authors.forename: K V
authors.initials: KV
authors.lastname: Mazaishvili
authors.affiliation: National Medical Surgical Centre named after N.I. Pirogov, Moscow, Russia.
authors.forename: T V
authors.initials: TV
authors.lastname: Khlevtova
authors.affiliation: National Medical Surgical Centre named after N.I. Pirogov, Moscow, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Tsyplyashchuk
authors.affiliation: National Medical Surgical Centre named after N.I. Pirogov, Moscow, Russia.
authors.forename: S E
authors.initials: SE
authors.lastname: Kharitonova
authors.affiliation: National Medical Surgical Centre named after N.I. Pirogov, Moscow, Russia.
authors.forename: S S
authors.initials: SS
authors.lastname: Akimov
mesh_terms: D000328:Adult; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods; D005260:Female; D005419:Flavonoids / Q000008:administration & dosage*; D006801:Humans; D017075:Laser Coagulation / Q000009:adverse effects / Q000379:methods; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000517:prevention & control*; D010689:Phlebitis / Q000209:etiology / Q000517:prevention & control; D011184:Postoperative Period; D020127:Recovery of Function / Q000187:drug effects; D012501:Saphenous Vein / Q000000981:diagnostic imaging; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods; D014648:Varicose Veins / Q000150:complications / Q000628:therapy; D014689:Venous Insufficiency / Q000209:etiology / Q000628:therapy
chemical_list: D005419:Flavonoids