title: [Clinical and electroencephalographic characteristics of specific language impairment in children and an evaluation of the efficacy of cerebrolysin].
abstract: To study different forms of specific language impairment in children and to evaluate the efficacy of cerebrolysin in clinical and electroencephalographic aspects.
  
  
  METHODS
  Authors examined 60 children, aged 5-7 years, with a specific language impairment (SLI).
  
  
  CONCLUSIONS
  The study showed the significantly higher severity of speech disorders, a higher degree of asthenia and dyspraxia/dysgnosia in a group of children with a disorder of receptive language (SLI-R) compared to children with a disorder of expressive speech (SLI-E). A comparative analysis of the EEG power spectra showed large values of slow theta-band EEG in children with SLI compared with healthy children. Children with SLI-R were characterized by the increase in theta rhythm power in the occipital region compared with children with SLI-E. The high efficacy of cerebrolysin in the treatment of this disease (an improvement was obtained in 73.3% of cases) was demonstrated, with the best effect in children with SLI-E (80.0% of cases).
authors.affiliation: N. Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: L S
authors.initials: LS
authors.lastname: Chutko
authors.affiliation: N. Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: S Yu
authors.initials: SY
authors.lastname: Surushkina
authors.affiliation: N. Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: E A
authors.initials: EA
authors.lastname: Yakovenko
authors.affiliation: N. Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: A V
authors.initials: AV
authors.lastname: Sergeev
authors.affiliation: N. Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: A V
authors.initials: AV
authors.lastname: Rozhkova
authors.affiliation: N. Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: L V
authors.initials: LV
authors.lastname: Anosova
authors.affiliation: N. Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: N P
authors.initials: NP
authors.lastname: Chistyakova
mesh_terms: D000596:Amino Acids / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D007802:Language; D007805:Language Development Disorders / Q000188:drug therapy* / Q000503:physiopathology*; D008297:Male; D009778:Occipital Lobe / Q000503:physiopathology; D013060:Speech / Q000502:physiology; D013826:Theta Rhythm
chemical_list: D000596:Amino Acids; C006952:cerebrolysin