title: Therapeutic efficacy of Cernilton in benign prostatic hyperplasia patients with histological prostatitis after transurethral resection of the prostate.
abstract: OBJECTIVE
  This study was to prospectively evaluate the therapeutic efficacy of Cernilton in benign prostatic hyperplasia (BPH) patients with histological prostatitis after transurethral resection of the prostate (TURP).
  
  
  METHODS
  One hundred patients with histological prostatitis were recruited from January 2007 to January 2013. All patients were divided into groups A (mild), B (moderate), and C (severe) based on symptom severity, and then randomly subgrouped into Cernilton group and control group. Patients in Cernilton group were treated with Cernilton for 3 months after TURP, while patients in control group received placebo. A series of patient indicators were evaluated before, perioperatively (peri), and after TURP.
  
  
  RESULTS
  The assessed indicators remained unchanged peri-TURP as compared to those before surgery. 6 months after TURP, indicators remained stable in group A, and significant differences were observed in the International Index of Erectile Function-5 (IIEF-5) in group B and in the storage symptom score (Ss), quality of life (QoL) and IEFF-5 in group C. In addition, there were significant differences in Ss, QoL and IEFF-5 between Cernilton group and control group.
  
  
  CONCLUSIONS
  In BPH patients with histological prostatitis after TURP, Cernilton can improve the lower urinary tract symptoms and sexual dysfunction depending on the grade of prostatitis.
authors.affiliation: Department of Urology, Affiliated Xinhua Hospital of Shanghai Jiaotong University School of Medicine Shanghai, China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Qian
authors.affiliation: Department of Urology, Affiliated Xinhua Hospital of Shanghai Jiaotong University School of Medicine Shanghai, China.
authors.forename: Xiangjie
authors.initials: X
authors.lastname: Kong
authors.affiliation: Department of Urology, Shanghai Kongjiang Hospital Shanghai, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Qian
authors.affiliation: Department of Urology, Affiliated Xinhua Hospital of Shanghai Jiaotong University School of Medicine Shanghai, China.
authors.forename: Ding
authors.initials: D
authors.lastname: Xu
authors.affiliation: Department of Urology, Affiliated Xinhua Hospital of Shanghai Jiaotong University School of Medicine Shanghai, China.
authors.forename: Hailong
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Ultrasound in Medicine, Affiliated Xinhua Hospital of Shanghai Jiaotong University School of Medicine Shanghai, China.
authors.forename: Yunkai
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Department of Pathology, Affiliated Xinhua Hospital of Shanghai Jiaotong University School of Medicine Shanghai, China.
authors.forename: Wenbing
authors.initials: W
authors.lastname: Guan
authors.affiliation: Department of Urology, Affiliated Tenth People's Hospital of Shanghai Tongji University School of Medicine Shanghai, China.
authors.forename: Junhua
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Department of Urology, Affiliated Ninth People's Hospital of Shanghai Jiaotong University School of Medicine Shanghai, China.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Urology, Affiliated Xinhua Hospital of Shanghai Jiaotong University School of Medicine Shanghai, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Qi
keywords: Prostatic hyperplasia; cernilton; histological prostatitis; transurethral resection of prostate