title: Interrelationships between indices of longitudinal movement of the common carotid artery wall and the conventional measures of subclinical arteriosclerosis.
abstract: Our objective was to study the interrelationships between longitudinal movement of the wall of the common carotid artery and the conventional measures of arteriosclerosis in a large and well-characterized study population. Successful longitudinal movement analyses were performed on 292 subjects. The peak-to-peak and retrograde amplitudes of the longitudinal movement were directly correlated with carotid artery distensibility (r = 0·21, P<0·001 and r = 0·23, P<0·001, respectively) and inversely correlated with pulse wave velocity (r = -0·14, P<0·05 and r = -0·17, P<0·01, respectively). All longitudinal motion parameters were independent of brachial flow-mediated dilatation and intima-media thickness. Our findings indicate that arterial stiffening modulates longitudinal movement and, therefore, measurement of longitudinal movement can be of value in the assessment of vascular health.
authors.affiliation: Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.|Department of Clinical Physiology and Nuclear Medicine, University of Eastern Finland, Kuopio, Finland.
authors.forename: S Helena
authors.initials: SH
authors.lastname: Taivainen
authors.affiliation: Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.|Department of Applied Physics, University of Eastern Finland, Kuopio, Finland.
authors.forename: Heikki
authors.initials: H
authors.lastname: Yli-Ollila
authors.affiliation: Department of Medicine, University of Turku, Turku, Finland.|Division of Medicine, Turku University Hospital, Turku, Finland.|Murdoch Children's Research Institute, Parkville, Vic., Australia.
authors.forename: Markus
authors.initials: M
authors.lastname: Juonala
authors.affiliation: Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.
authors.forename: Mika
authors.initials: M
authors.lastname: Kähönen
authors.affiliation: Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.|Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
authors.forename: Olli T
authors.initials: OT
authors.lastname: Raitakari
authors.affiliation: Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
authors.forename: Tiina M
authors.initials: TM
authors.lastname: Laitinen
authors.affiliation: Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.|Department of Clinical Physiology and Nuclear Medicine, University of Eastern Finland, Kuopio, Finland.
authors.forename: Tomi P
authors.initials: TP
authors.lastname: Laitinen
mesh_terms: D000328:Adult; D058070:Asymptomatic Diseases; D001696:Biomechanical Phenomena; D001783:Blood Flow Velocity; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000503:physiopathology; D059168:Carotid Intima-Media Thickness; D003430:Cross-Sectional Studies; D005260:Female; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D011237:Predictive Value of Tests; D063177:Pulse Wave Analysis; D012039:Regional Blood Flow; D014463:Ultrasonography / Q000379:methods*; D059289:Vascular Stiffness; D014664:Vasodilation; D014741:Video Recording
keywords: arterial stiffness; carotid artery distensibility; flow-mediated dilatation; intima-media thickness; motion tracking; pulse wave velocity; ultrasound imaging