title: Adhesive Enrichment and Membrane Turnover at the Heart of Cardiopharyngeal Induction.
abstract: Differential inductive signaling during asymmetric division of progenitor cells specifies the heart lineage in Ciona intestinalis. In this issue of Developmental Cell, Cota and Davidson (2015) show that differential induction is mediated by FGF receptor regionalization, resulting from asymmetric cell-matrix adhesion and reduced mitotic turnover of polarized Caveolin-rich membrane domains.
authors.affiliation: Aix-Marseille University, IBDM CNRS UMR 7288, Campus de Luminy Case 907, 13288 Marseille Cedex 9, France. Electronic address: robert.kelly@univ-amu.fr.
authors.forename: Robert G
authors.initials: RG
authors.lastname: Kelly
mesh_terms: D000818:Animals; D002455:Cell Division / Q000502:physiology*; D019070:Cell Lineage / Q000502:physiology*; D002938:Ciona intestinalis / Q000166:cytology*; D005346:Fibroblast Growth Factors / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D006321:Heart / Q000196:embryology*; D009206:Myocardium / Q000166:cytology*
chemical_list: D005346:Fibroblast Growth Factors