title: Braun enteroenterostomy reduces delayed gastric emptying: A systematic review and meta-analysis.
abstract: BACKGROUND
  It remains controversial whether the additional Braun enteroenterostomy (BEE) is necessary in decreasing delayed gastric emptying (DGE) following pancreaticoduodenectomy (PD). This meta-analysis aims to assess the efficacy of the additional BEE in reducing DGE after PD.
  
  
  METHODS
  PubMed, EMBASE, Science Citation Index and The Cochrane Library were searched to identify relevant studies. Articles published before May 15, 2015 comparing BEE with traditional gastrojejunostomy during PD were selected. The evaluated end points consist of intro-operative outcomes as well as postoperative complications.
  
  
  RESULTS
  Seven observational clinical studies that recruited 1401 patients were included. This meta-analysis indicated that the occurrence of DGE was lower in Braun group (odds ratio [OR], 0.30; 95% confidence interval [CI], 0.15 to 0.60; P = 0.0007). Overall morbidity (OR, 0.61; 95%CI, 0.47 to 0.80; P = 0.0003) and the length of hospital stay (LOS) (weighted mean difference [WMD], -1.80; 95%CI, -3.4 to -0.18; p = 0.03) were also in favor of the Braun group. However, Braun group had no advantage over Non-Braun group in terms of intra-operative blood loss, mortality, pancreatic fistula, bile Leakage and intra-abdominal abscess.
  
  
  CONCLUSIONS
  The additional of BEE plays an important role in reducing DGE, overall morbidity and LOS.
authors.affiliation: Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Ming-quan
authors.initials: MQ
authors.lastname: Huang
authors.affiliation: Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Mou
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Jing-yu
authors.initials: JY
authors.lastname: Mao
authors.affiliation: Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address: bo-le@medmail.com.cn.
authors.forename: Bo-le
authors.initials: BL
authors.lastname: Tian
mesh_terms: D018784:Abdominal Abscess / Q000209:etiology; D000714:Anastomosis, Surgical / Q000379:methods; D016063:Blood Loss, Surgical; D004766:Enterostomy / Q000379:methods*; D018589:Gastroparesis / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D010185:Pancreatic Fistula / Q000209:etiology; D016577:Pancreaticoduodenectomy / Q000009:adverse effects; D016896:Treatment Outcome
keywords: Braun enteroenterostomy; Delayed gastric emptying; Meta-analysis; Pancreaticoduodenectomy