title: Unusual Presentation of Melioidosis in a Case of Pseudoaneurysm of Descending Thoracic Aorta: Review of Two Case Reports.
abstract: BACKGROUND
  Melioidosis is a rapidly fatal infectious disease caused by Burkholderia pseudomallei, an agent of potential biothreat, endemic in several parts of India. Most melioidosis-induced infected aneurysms are located in the abdominal or thoracic aorta.
  
  
  METHODS
  We reported two unusual cases of melioidosis resulting in pseudoaneurysm of the descending thoracic aorta. In both cases, blood cultures yielded B. pseudomallei. The first patient was managed with resection of aneurysm and reconstruction with Dacron graft followed by medical treatment and was discharged uneventfully. The second patient died within one week of admission before the infecting etiological agent was identified and aneurysmal repair was planned.
  
  
  CONCLUSIONS
  A high clinical index of suspicion, especially in areas of endemicity is essential for timely management of intracavitary infected pseudoaneurysms caused by B. pseudomallei and use of rapid microbiological techniques, such as bact/alert 3D system, which enables rapid and early recovery of the etiological agent.
authors.affiliation: Department of Microbiology, Nizam's Institute of Medical Sciences, Hyderabad, India.
authors.forename: Kanne
authors.initials: K
authors.lastname: Padmaja
authors.affiliation: Department of Microbiology, Nizam's Institute of Medical Sciences, Hyderabad, India.
authors.forename: Vemu
authors.initials: V
authors.lastname: Lakshmi
authors.affiliation: Department of Microbiology, Nizam's Institute of Medical Sciences, Hyderabad, India.
authors.forename: Sukanya
authors.initials: S
authors.lastname: Sudhaharan
authors.affiliation: Department of General Medicine, Nizam's Institute of Medical Sciences, Hyderabad, India.
authors.forename: Subbalaxmi
authors.initials: S
authors.lastname: Venkata Surya Malladi
authors.affiliation: Department of Cardiothoracic Surgery, Nizam's Institute of Medical Sciences, Hyderabad, India.
authors.forename: Palanki
authors.initials: P
authors.lastname: Gopal
authors.affiliation: Department of Cardiothoracic Surgery, Nizam's Institute of Medical Sciences, Hyderabad, India.
authors.forename: Kumar
authors.initials: K
authors.lastname: Venkata Ravinuthala
keywords: Bacteremia; Infected Aneurysm; Sepsis; Virulence