title: Two-year clinical outcomes following non-surgical mechanical therapy of peri-implantitis with adjunctive diode laser application.
abstract: BACKGROUND
  Non-surgical mechanical therapy of peri-implantitis (PI) with/without adjunctive measures yields limited clinical improvements.
  
  
  OBJECTIVE
  To evaluate the clinical outcomes following non-surgical mechanical therapy of PI with adjunctive application of a diode laser after an observation period ≥2 years.
  
  
  METHODS
  At baseline (BL), 15 patients with 23 implants with a sandblasted and acid-etched (SLA) surface diagnosed with PI were enrolled and treated. PI was defined as presence of probing pocket depths (PPD) ≥5 mm with bleeding on probing (BoP) and/or suppuration and ≥2 threads with bone loss after delivery of the restoration. Implant sites were treated with carbon fiber and metal curettes followed by repeated application of a diode laser 3x for 30 s (settings: 810 nm, 2.5 W, 50 Hz, 10 ms). This procedure was performed at Day 0 (i.e., baseline), 7 and 14. Adjunctive antiseptics or adjunctive systemic antibiotics were not prescribed.
  
  
  RESULTS
  All implants were in function after 2 years. The deepest PPD decreased from 7.5 ± 2.6 mm to 3.6 ± 0.7 mm at buccal (P < 0.0001) and from 7.7 ± 2.1 mm to 3.8 ± 0.9 mm at oral sites (P < 0.0001), respectively. The % of implants with ≥1 site with BoP decreased from 100% at BL to 43% after 2 years (P = 0.0002). The % of implants with suppuration decreased from 87% at BL to 0% after 2 years (P < 0.0001).
  
  
  CONCLUSIONS
  Non-surgical mechanical therapy of PI with adjunctive repeated application of a diode laser yielded significant clinical improvements after an observation period of at least 2 years.
authors.affiliation: Private practice, Bern, Switzerland.
authors.forename: Gérald R
authors.initials: GR
authors.lastname: Mettraux
authors.affiliation: School of Dental Medicine, Department of Periodontology, University of Bern, Bern, Switzerland.
authors.forename: Anton
authors.initials: A
authors.lastname: Sculean
authors.affiliation: School of Dental Medicine, University of Bern, Bern, Switzerland.
authors.forename: Walter B
authors.initials: WB
authors.lastname: Bürgin
authors.affiliation: School of Dental Medicine, Department of Periodontology, University of Bern, Bern, Switzerland.
authors.forename: Giovanni E
authors.initials: GE
authors.lastname: Salvi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D057873:Peri-Implantitis / Q000628:therapy*; D012189:Retrospective Studies; D013357:Subgingival Curettage; D013492:Suppuration / Q000628:therapy
keywords: biostimulation; decontamination; dental implant; diode laser; inflammation; peri-implantitis