title: Septic arthritis in immunocompetent and immunosuppressed hosts.
abstract: Septic arthritis has long been considered an orthopedic emergency. Historically, Neisseria gonorrhoeae and Staphylococcus aureus have been the most common causes of septic arthritis worldwide but in the modern era of biological therapy and extensive use of prosthetic joint replacements, the spectrum of microbiological causes of septic arthritis has widened considerably. There are also new approaches to diagnosis but therapy remains a challenge, with a need for careful consideration of a combined medical and surgical approach in most cases.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, National University Hospital, National University Health System, Singapore. Electronic address: alvin_dy_wang@nuhs.edu.sg.
authors.forename: Dingyuan Alvin
authors.initials: DA
authors.lastname: Wang
authors.affiliation: Division of Infectious Diseases, Department of Medicine, National University Hospital, National University Health System, Singapore; Department of Medicine, National University of Singapore, Singapore.
authors.forename: Paul Anantharajah
authors.initials: PA
authors.lastname: Tambyah
mesh_terms: D001170:Arthritis, Infectious / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D007121:Immunocompetence / Q000502:physiology*; D016867:Immunocompromised Host; D013203:Staphylococcal Infections / Q000276:immunology* / Q000503:physiopathology; D013211:Staphylococcus aureus / Q000302:isolation & purification
keywords: Immunocompromised host; Prosthetic joint infection; Septic arthritis