title: Epidemiological evaluation of YAG capsulotomy incidence for posterior capsule opacification in various intraocular lenses in Japanese eyes.
abstract: OBJECTIVE
  We investigated the yttrium aluminum garnet (YAG) capsulotomy rates in various intraocular lenses (IOLs).
  
  
  METHODS
  We retrospectively analyzed 23,440 eyes implanted with either MA60BM, MA60AC, VA-60BB, CeeOnEdge, Clariflex, Technis Z9002, SI-40NB, or UV26T IOLs. We calculated the YAG capsulotomy rates at 1, 3, 5, and 10 years post lens implantation.
  
  
  RESULTS
  YAG capsulotomy rates at 3 years postimplantation for the eight groups of IOLs were, respectively, 3.7%, 3.9%, 23.7%, 3.4%, 4.5%, 4.7%, 10.4%, and 21.0%. YAG capsulotomy rates at 10 years postimplantation for the MA60BM and SI-40NB IOLs were, respectively, 9.1% and 15% (P<0.05). The average YAG rates for all sharp-edged and round-edged IOLs at 5 years postimplantation were, respectively, 5.2%±0.7% and 25.6%±9.0% (P<0.05).
  
  
  CONCLUSIONS
  In all studied IOLs, posterior capsule opacification prevention seemed to be associated with the posterior optic sharp-edge design. Round-edged silicone IOLs may also retard posterior capsule opacification formation, though not as much as sharp-edged IOLs. As the follow-up period progressed, round-edged silicone IOLs showed significantly higher YAG rates than sharp-edged IOLs.
authors.affiliation: Department of Ophthalmology, Hyogo College of Medicine, Hyogo, Japan ; Nishi Eye Hospital, Osaka, Japan.
authors.forename: Yutaro
authors.initials: Y
authors.lastname: Nishi
authors.affiliation: Department of Ophthalmology, Hyogo College of Medicine, Hyogo, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Ikeda
authors.affiliation: Nishi Eye Hospital, Osaka, Japan.
authors.forename: Kayo
authors.initials: K
authors.lastname: Nishi
authors.affiliation: Department of Ophthalmology, Hyogo College of Medicine, Hyogo, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Mimura
keywords: chi-square test; implantation surgery; intraocular lenses; posterior capsule opacification; sharp optic edge; silicone