title: Neurofibroma and lipoma in association with giant congenital melanocytic nevus coexisting in one nodule: a case report.
abstract: Giant congenital melanocytic nevi (GCMN) are rare conditions that defined as melanocytic lesion recognized at birth, which will reach a diameter larger than 20 cm, and they occur in about 1 per 500,000 newborns. Despite its rarity, they may associate with severe abnormalities like spina bifida occulta, meningocele, club foot and hypertrophy or atrophy of deeper structures of a limb, Carney complex, premature aging syndromes, neurofibroma, vitiligo, lipoma and dysplasia of bilateral hip impact on the patient. In this case, we report a 3-years-old male child presenting a GCMN with large, blackish, and thick nevus covering over the entire neck, back, and lower to the waist level. We highlight the importance of proper histopathological examination of the biopsy taken from the single huge nodule which revealed features of both neurofibroma and lipoma coexisting. The objective of this paper is to report a rare case with the clinical and pathologic findings.
authors.affiliation: Department of Dermatology, The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Shang
authors.affiliation: Department of Plastic Surgery, The Third Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Dai
authors.affiliation: Department of Plastic Surgery, The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Yongqiang
authors.initials: Y
authors.lastname: Ren
keywords: Giant congenital melanocytic nevi; lipoma; neurofibroma