title: Uveal effusion syndrome mimicking severe chronic posterior uveitis: a case series of seven eyes of four patients.
abstract: OBJECTIVE
  To describe the clinical findings and management of eyes affected by uveal effusion syndrome (UES) presenting with clinical features mimicking inflammatory ocular diseases, treated using individualized surgical approaches.
  
  
  METHODS
  We report a consecutive interventional case series of seven eyes of four patients affected by UES. On presentation in our clinic, all patients showed signs of steroid effects as a consequence of a presumptive diagnosis; one eye had undergone vitrectomy for retinal detachment (RD), without benefit. Diagnosis of UES was based on ophthalmic examination, ultrasonography, fluorescein angiography, biometry and magnetic resonance imaging. Five eyes with active disease were treated using scleral thinning surgical procedures based on the extent and characteristics of the disease: sclerectomy sites were ultrasound-guided to the area of maximal choroidal swelling, associated with evacuative puncture in the case of bilateral funnel-shaped RD.
  
  
  RESULTS
  One patient was diagnosed with type 1 UES, two with type 2, and one with type 3. Mean postoperative follow-up was 26 months. In all eyes, surgery resolved the ciliochoroidal and retinal detachment and improved visual acuity. In two eyes, visual restoration was limited by a prolonged disease course.
  
  
  CONCLUSIONS
  UES may be mistaken for other sources of ciliochoroidal effusion. Early diagnosis and treatment is critical to avoid unnecessary procedures and to prevent severe visual loss as a result of neuroretinal damage. Surgical treatment based on the extent and characteristics of the disease may be effective for the resolution of ciliochoroidal effusion, even in type 3 UES, where conventional surgery has proved unsuccessful.
authors.affiliation: Department of Ophthalmology, Ospedale S. Cuore - Don Calabria, Via Don Sempreboni,5, Negrar, 37024, Verona, Italy. emi_maggio@yahoo.it.
authors.forename: Emilia
authors.initials: E
authors.lastname: Maggio
authors.affiliation: Department of Ophthalmology, Ospedale S. Cuore - Don Calabria, Via Don Sempreboni,5, Negrar, 37024, Verona, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Polito
authors.affiliation: Department of Ophthalmology, Ospedale S. Cuore - Don Calabria, Via Don Sempreboni,5, Negrar, 37024, Verona, Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Prigione
authors.affiliation: Department of Ophthalmology, Ospedale S. Cuore - Don Calabria, Via Don Sempreboni,5, Negrar, 37024, Verona, Italy.
authors.forename: Grazia
authors.initials: G
authors.lastname: Pertile
mesh_terms: D000293:Adolescent; D000328:Adult; D001699:Biometry; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D012599:Sclerostomy; D041623:Tomography, Optical Coherence; D014603:Uveal Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D015866:Uveitis, Posterior / Q000175:diagnosis*; D014792:Visual Acuity / Q000502:physiology
keywords: Ciliochoroidal effusion; Multimodal imaging; Scleral thinning surgery; Ultrasound-guided surgery; Uveal effusion syndrome