title: Rapid Cell Patterning Induced by Differential Topography on Silica Nanofractal Substrates.
abstract: Predesigned silica nanofractal substrates are utilized for rapid cell patterning, based on differential cell adhesion originating from surface topographic interactions. Cell patterns with various shapes are successfully formed, from simple geometrical shapes to a complex "CELL" symbol. This study assists understanding of cell-substrate interactions and facilitates biological applications.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic SolidsInstitute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Chemistry and Chemical Engineering, University of the Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors.forename: Guannan
authors.initials: G
authors.lastname: Li
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic SolidsInstitute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Chemistry and Chemical Engineering, University of the Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors.forename: Gao
authors.initials: G
authors.lastname: Yang
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic SolidsInstitute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Chemistry and Chemical Engineering, University of the Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors.forename: Pengchao
authors.initials: P
authors.lastname: Zhang
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic SolidsInstitute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Chemistry and Chemical Engineering, University of the Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors.forename: Yingying
authors.initials: Y
authors.lastname: Li
authors.affiliation: Laboratory for Bio-Inspired Smart Interface Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Jingxin
authors.initials: J
authors.lastname: Meng
authors.affiliation: Laboratory for Bio-Inspired Smart Interface Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Hongliang
authors.initials: H
authors.lastname: Liu
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic SolidsInstitute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|Laboratory for Bio-Inspired Smart Interface Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Shutao
authors.initials: S
authors.lastname: Wang
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D002450:Cell Communication; D018929:Cell Culture Techniques / Q000295:instrumentation / Q000379:methods; D002465:Cell Movement / Q000502:physiology*; D005347:Fibroblasts / Q000166:cytology* / Q000502:physiology*; D051379:Mice; D041681:NIH 3T3 Cells; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties; D013997:Time Factors; D054457:Tissue Scaffolds / Q000737:chemistry
chemical_list: D012822:Silicon Dioxide
keywords: cell adhesion; cell patterning; silica nanofractals; topographic interactions