title: Retrospective Analysis of Motor Development in Infants at High and Low Risk for Autism Spectrum Disorder.
abstract: OBJECTIVE
  To measure upper-extremity and gross motor skill development in infants with and without risk factors for autism spectrum disorder (ASD).
  
  
  METHODS
  Data were coded retrospectively from 39 infants who participated in longitudinal structured early developmental assessments. Twenty-five infants were at high risk for ASD, and the remaining 14 infants were classified as low risk. Upper-extremity and motor skill development were coded at ages 2, 4, and 6 mo. Five infants went on to receive an ASD diagnosis at age 2-4 yr.
  
  
  RESULTS
  Infants at high risk for ASD demonstrated fewer midline behaviors with the upper extremities and delayed motor skill development than the low-risk group. Differences in motor skills were most apparent at age 4 mo.
  
  
  CONCLUSIONS
  Early monitoring for motor delay in infants at high risk for ASD is warranted. Midline control and play with the upper extremities and overall motor skill development are possible assessment and therapeutic targets.
authors.affiliation: Jill C. Heathcock, MPT, PhD, is Assistant Professor, Division of Physical Therapy, The Ohio State University, Columbus; jill.heathcock@osumc.edu.
authors.forename: Jill C
authors.initials: JC
authors.lastname: Heathcock
authors.affiliation: Kelly Tanner, OTR/L, PhD, is Assistant Clinical Professor, Division of Occupational Therapy, School of Health and Rehabilitation Science, The Ohio State University, Columbus.
authors.forename: Kelly
authors.initials: K
authors.lastname: Tanner
authors.affiliation: Danielle Robson, PhD, is Clinical Psychologist, School of Psychology, Faculty of Social and Behavioural Sciences, Flinders University, Adelaide, South Australia, Australia.
authors.forename: Danielle
authors.initials: D
authors.lastname: Robson
authors.affiliation: Robyn Young, PhD, is Associate Professor, School of Psychology, Faculty of Social and Behavioural Sciences, Flinders University, Adelaide, South Australia, Australia.
authors.forename: Robyn
authors.initials: R
authors.lastname: Young
authors.affiliation: Alison E. Lane, PhD, OTR/L, is Associate Professor, Occupational Therapy, School of Health Sciences, University of Newcastle, Callahan, New South Wales, Australia.
authors.forename: Alison E
authors.initials: AE
authors.lastname: Lane