title: Identification of a novel gammaherpesvirus associated with (muco)cutaneous lesions in harbour porpoises (Phocoena phocoena).
abstract: Herpesviruses infect a wide range of vertebrates, including toothed whales of the order Cetacea. One of the smallest toothed whales is the harbour porpoise (Phocoena phocoena), which is widespread in the coastal waters of the northern hemisphere, including the North Sea. Here, we describe the detection and phylogenetic analysis of a novel gammaherpesvirus associated with mucocutaneous and skin lesions in stranded harbour porpoises along the Dutch coast, tentatively designated phocoenid herpesvirus 1 (PhoHV1). Phylogenetically, PhoHV1 forms a monophyletic clade with all other gammaherpesviruses described in toothed whales (Odontoceti) to date, suggesting a common evolutionary origin.
authors.affiliation: Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.158, 3508 TD, Utrecht, The Netherlands. s.j.vanbeurden@uu.nl.
authors.forename: Steven J
authors.initials: SJ
authors.lastname: van Beurden
authors.affiliation: Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.158, 3508 TD, Utrecht, The Netherlands.
authors.forename: Lonneke L
authors.initials: LL
authors.lastname: IJsseldijk
authors.affiliation: Molecular Host Defence Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.158, 3508 TD, Utrecht, The Netherlands.
authors.forename: Soledad R
authors.initials: SR
authors.lastname: Ordonez
authors.affiliation: Institut für Virologie, Justus-Liebig-Universität Giessen, Frankfurter Str. 109, 35392, Giessen, Germany.
authors.forename: Christine
authors.initials: C
authors.lastname: Förster
authors.affiliation: Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.158, 3508 TD, Utrecht, The Netherlands.
authors.forename: Geert
authors.initials: G
authors.lastname: de Vrieze
authors.affiliation: Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.158, 3508 TD, Utrecht, The Netherlands.|Dutch Wildlife Health Centre, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.158, 3508 TD, Utrecht, The Netherlands.
authors.forename: Andrea
authors.initials: A
authors.lastname: Gröne
authors.affiliation: Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.158, 3508 TD, Utrecht, The Netherlands.
authors.forename: M Hélène
authors.initials: MH
authors.lastname: Verheije
authors.affiliation: Dutch Wildlife Health Centre, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.158, 3508 TD, Utrecht, The Netherlands.
authors.forename: Marja
authors.initials: M
authors.lastname: Kik
mesh_terms: D000818:Animals; D005260:Female; D018142:Gammaherpesvirinae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D006566:Herpesviridae Infections / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D008297:Male; D008969:Molecular Sequence Data; D050741:Phocoena / Q000821:virology*; D010802:Phylogeny