title: Comparison of two types of colectomy in treating slow transit constipation with or without melanosis coli.
abstract: OBJECTIVE
  To compare the follow-up outcomes of ileosigmoidal anastomosis (ISA) and caecorectal anastomosis (CRA) in patients with slow transit constipation (STC) with or without melanosis coli (MC).
  
  
  METHODS
  We collected the clinical data of 48 STC patients with or without MC from May 2002 to May 2007. Twenty-six patients underwent CRA (14 with MC) and 22 cases received ISA (14 with MC). A 3-year postoperative follow-up was conducted.
  
  
  RESULTS
  CRA improved the quality of life [evaluated by the gastrointestinal quality of life index (GIQLI)] in patients without MC, but was inferior to ISA in stool frequency and Wexner and GIQLI scores for MC patients. In the CRA group, patients with MC suffered worse outcomes than those without MC.
  
  
  CONCLUSIONS
  CRA is more suitable for STC patients without MC; however, for STC patients with MC, ISA is a better choice.
authors.affiliation: Ji-Wei Sun, Jia-Ni Gu, Peng Du, Wei Chen, Department of Anal and Rectal Surgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
authors.forename: Ji-Wei
authors.initials: JW
authors.lastname: Sun
authors.affiliation: Ji-Wei Sun, Jia-Ni Gu, Peng Du, Wei Chen, Department of Anal and Rectal Surgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
authors.forename: Jia-Ni
authors.initials: JN
authors.lastname: Gu
authors.affiliation: Ji-Wei Sun, Jia-Ni Gu, Peng Du, Wei Chen, Department of Anal and Rectal Surgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Du
authors.affiliation: Ji-Wei Sun, Jia-Ni Gu, Peng Du, Wei Chen, Department of Anal and Rectal Surgery, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical; D003082:Colectomy / Q000009:adverse effects / Q000379:methods*; D003106:Colon / Q000503:physiopathology / Q000601:surgery*; D003248:Constipation / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D003672:Defecation; D005260:Female; D005772:Gastrointestinal Transit; D006801:Humans; D008297:Male; D008548:Melanosis / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D018579:Patient Selection; D011788:Quality of Life; D020127:Recovery of Function; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome
keywords: Caecorectal anastomosis; Constipation; Ileosigmoidal anastomosis; Melanosis coli; Prognosis