title: Size-controllable DNA nanoribbons assembled from three types of reusable brick single-strand DNA tiles.
abstract: Precise control of nanostructure is a significant goal shared by supramolecular chemistry, nanotechnology and materials science. In DNA nanotechnology, methods of constructing desired DNA nanostructures using programmable DNA strands have been studied extensively and have become a promising branch of research, but developing universal and low-cost (in the sense of using fewer types of DNA strands) methods remains a challenge. In this work, we propose a novel approach to assemble size-controllable DNA nanoribbons with three types of reusable brick SSTs (single-stranded DNA tiles), where the control of ribbon size is achieved by regulating the concentration ratio between manipulative strands and packed single-stranded DNA tiles. In our method, three types of brick SSTs are sufficient in assembling DNA nanoribbons of different sizes, which is much less than the number of types of unique tile-programmable assembling strategy, thus achieving a universal and low-cost method. The assembled DNA nanoribbons are observed and analyzed by atomic force microscopy (AFM). Experimental observations strongly suggest the feasibility and reliability of our method.
authors.affiliation: Key Laboratory of Image Information Processing and Intelligent Control, School of Automation, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Shi
authors.affiliation: Key Laboratory of Image Information Processing and Intelligent Control, School of Automation, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China.
authors.forename: Congzhou
authors.initials: C
authors.lastname: Chen
authors.affiliation: Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China. lixinwhu@189.cn.
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.affiliation: College of Computer & Communication Engineering, China University of Petroleum, Qingdao 266580, Shandong, China. taosong@hust.edu.cn.
authors.forename: Tao
authors.initials: T
authors.lastname: Song
authors.affiliation: Key Laboratory of Image Information Processing and Intelligent Control, School of Automation, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Key Laboratory of Image Information Processing and Intelligent Control, School of Automation, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: School of Electrical and Information Engineering, Henan Key Lab of Information-Based Electrical Appliances, Zhengzhou University of Light Industry, Zhengzhou, 450002, China.
authors.forename: Yanfeng
authors.initials: Y
authors.lastname: Wang
mesh_terms: D004277:DNA, Single-Stranded / Q000737:chemistry* / Q000648:ultrastructure; D018625:Microscopy, Atomic Force; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010316:Particle Size; D015203:Reproducibility of Results
chemical_list: D004277:DNA, Single-Stranded; D037742:Nanotubes, Carbon