title: MRI features of breast lymphoma: preliminary experience in seven cases.
abstract: OBJECTIVE
  We aimed to evaluate the imaging features of breast lymphoma using magnetic resonance imaging (MRI).
  
  
  METHODS
  This retrospective study consisted of seven patients with pathologically confirmed breast lymphoma. The breast lymphomas were primary in six patients and secondary in one patient. All patients underwent preoperative dynamic contrast-enhanced MRI and one underwent additional diffusion-weighted imaging (DWI) with a b value of 600 s/mm2. Morphologic characteristics, enhancement features, and apparent diffusion coefficient (ADC) values were reviewed.
  
  
  RESULTS
  On MRI, three patients presented with a single mass, one with two masses, two with multiple masses, and one with a single mass and a contralateral focal enhancement. The MRI features of the eight biopsied masses in seven patients were analyzed. On MRI, the margins were irregular in six masses (75%) and spiculated in two (25%). Seven masses (87.5%) displayed homogeneous internal enhancement, while one (12.5%) showed rim enhancement. Seven masses (87.5%) showed a washout pattern and one (12.5%) showed a plateau pattern. The penetrating vessel sign was found in two masses (25%). One patient with two masses underwent DWI. Both masses showed hyperintense signal on DWI with ADC values of 0.867×10-3 mm2/s and 0.732×10-3 mm2/s, respectively.
  
  
  CONCLUSIONS
  Breast lymphoma commonly presents as a homogeneously enhancing mass with irregular margins and displays a washout curve pattern on dynamic MRI. A low ADC value may also indicate a possible diagnosis of breast lymphoma.
authors.affiliation: Department of Radiology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. dbwang8@aliyun.com.
authors.forename: Lijun
authors.initials: L
authors.lastname: Wang
authors.forename: Dengbin
authors.initials: D
authors.lastname: Wang
authors.forename: Weimin
authors.initials: W
authors.lastname: Chai
authors.forename: Xiaochun
authors.initials: X
authors.lastname: Fei
authors.forename: Ran
authors.initials: R
authors.lastname: Luo
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Li
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging* / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D012189:Retrospective Studies