title: The complete chloroplast genome sequence of an important medicinal plant Cynanchum wilfordii (Maxim.) Hemsl. (Apocynaceae).
abstract: Cynanchum wilfordii (Maxim.) Hemsl. is a traditional medicinal herb belonging to the Asclepiadoideae subfamily, whose dried roots have been used as traditional medicine in Asia. The complete chloroplast genome of C. wilfordii was generated by de novo assembly using the small amount of whole genome sequencing data. The chloroplast genome of C. wilfordii was 161 241 bp long, composed of large single copy region (91 995 bp), small single copy region (19 930 bp) and a pair of inverted repeat regions (24 658 bp). The overall GC contents of the chloroplast genome was 37.8%. A total of 114 genes were annotated, which included 80 protein-coding genes, 30 tRNA genes and 4 rRNA genes. Phylogenetic analysis with the reported chloroplast genomes revealed that C. wilfordii is most closely related to Asclepias nivea (Caribbean milkweed) and Asclepias syriaca (common milkweed) within the Asclepiadoideae subfamily.
authors.affiliation: a Department of Plant Science, Plant Genomics and Breeding Institute, and Research Institute for Agriculture and Life Sciences , College of Agriculture and Life Sciences, Seoul National University , Seoul , Republic of Korea .
authors.forename: Hyun-Seung
authors.initials: HS
authors.lastname: Park
authors.affiliation: b Herbal Medicine Research Division, National Institute of Food and Drug Safety Evaluation, Cheongwon-Gun , Chungbuk , Republic of Korea .
authors.forename: Kyu-Yeob
authors.initials: KY
authors.lastname: Kim
authors.affiliation: a Department of Plant Science, Plant Genomics and Breeding Institute, and Research Institute for Agriculture and Life Sciences , College of Agriculture and Life Sciences, Seoul National University , Seoul , Republic of Korea .|c Phyzen Genomics Institute , Kwanak-gu, Seoul , Republic of Korea , and.
authors.forename: Kyunghee
authors.initials: K
authors.lastname: Kim
authors.affiliation: a Department of Plant Science, Plant Genomics and Breeding Institute, and Research Institute for Agriculture and Life Sciences , College of Agriculture and Life Sciences, Seoul National University , Seoul , Republic of Korea .
authors.forename: Sang-Choon
authors.initials: SC
authors.lastname: Lee
authors.affiliation: a Department of Plant Science, Plant Genomics and Breeding Institute, and Research Institute for Agriculture and Life Sciences , College of Agriculture and Life Sciences, Seoul National University , Seoul , Republic of Korea .
authors.forename: Junki
authors.initials: J
authors.lastname: Lee
authors.affiliation: b Herbal Medicine Research Division, National Institute of Food and Drug Safety Evaluation, Cheongwon-Gun , Chungbuk , Republic of Korea .
authors.forename: Rack Seon
authors.initials: RS
authors.lastname: Seong
authors.affiliation: b Herbal Medicine Research Division, National Institute of Food and Drug Safety Evaluation, Cheongwon-Gun , Chungbuk , Republic of Korea .
authors.forename: Young Hun
authors.initials: YH
authors.lastname: Shim
authors.affiliation: d College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University , Seoul , Republic of Korea.
authors.forename: Sang Hyun
authors.initials: SH
authors.lastname: Sung
authors.affiliation: a Department of Plant Science, Plant Genomics and Breeding Institute, and Research Institute for Agriculture and Life Sciences , College of Agriculture and Life Sciences, Seoul National University , Seoul , Republic of Korea .
authors.forename: Tae-Jin
authors.initials: TJ
authors.lastname: Yang
mesh_terms: D001482:Base Composition; D031105:Cynanchum / Q000235:genetics*; D019143:Evolution, Molecular; D054628:Genome, Chloroplast; D055670:Medicine, Korean Traditional; D010802:Phylogeny; D010946:Plants, Medicinal / Q000235:genetics; D000073336:Whole Genome Sequencing
keywords: Chloroplast; Cynanchum wilfordii; genome sequence; medicinal plant