title: Genome-wide association study of growth traits in Jinghai Yellow chicken hens using SLAF-seq technology.
abstract: In this study, we performed a new genome-wide association study using SLAF-seq technology. A total of 19 single nucleotide polymorphism effects involving nine different SNP markers reached 5% Bonferroni-corrected genome-wide significance. In addition, a 5-Mb region spanning 72.9-77.9 Mb on GGA4, exhibiting many significant SNP effects, was identified. The LDB2 gene in this region had a very strong association with body weight. Another SNP on GGA1, located in the INTS6 gene, had the strongest association with late body weight (weeks 10-16). Some of the SNPs that reached suggestive significance level overlapped with previously reported quantitative trait locus regions.
authors.affiliation: College of Animal Science and Technology, Yangzhou University, Jiangsu Yangzhou, 225009, China.|Key Laboratory for Animal Genetics, Breeding, Reproduction and Molecular Design of Jiangsu Province, Jiangsu Yangzhou, 225009, China.|College of life science and environmetal resource, Yichun university, Jiangxi Yichun, 36000, China.
authors.forename: W H
authors.initials: WH
authors.lastname: Wang
authors.affiliation: College of Animal Science and Technology, Yangzhou University, Jiangsu Yangzhou, 225009, China.|Key Laboratory for Animal Genetics, Breeding, Reproduction and Molecular Design of Jiangsu Province, Jiangsu Yangzhou, 225009, China.
authors.forename: J Y
authors.initials: JY
authors.lastname: Wang
authors.affiliation: College of Animal Science and Technology, Yangzhou University, Jiangsu Yangzhou, 225009, China.|Key Laboratory for Animal Genetics, Breeding, Reproduction and Molecular Design of Jiangsu Province, Jiangsu Yangzhou, 225009, China.
authors.forename: T
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Jiangsu Jinghai Industry Poultry Group Co, Ltd., Jiangsu Nantong, 226103, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Biomarker Technologies Corporation, Beijing, 101300, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Animal Science and Technology, Yangzhou University, Jiangsu Yangzhou, 225009, China.|Key Laboratory for Animal Genetics, Breeding, Reproduction and Molecular Design of Jiangsu Province, Jiangsu Yangzhou, 225009, China.
authors.forename: K
authors.initials: K
authors.lastname: Han
mesh_terms: D000818:Animals; D001835:Body Weight / Q000235:genetics*; D002645:Chickens / Q000235:genetics* / Q000254:growth & development; D005260:Female; D005819:Genetic Markers; D055106:Genome-Wide Association Study / Q000662:veterinary; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci
chemical_list: D005819:Genetic Markers
keywords: Bonferroni-corrected P-value; GWAS; LIM domain binding 2; integrator complex subunit 6