title: Use of Deslorelin Acetate Implants to Mitigate Aggression in Two Adult Male Domestic Turkeys (Meleagris gallopavo) and Correlating Plasma Testosterone Concentrations.
abstract: Two adult, male domestic turkeys were treated with implants of deslorelin acetate, a gonadotropin-releasing hormone agonist, to reduce intermale aggression and aggression directed toward the animal care team at a zoologic institution. The turkeys were manually restrained and either two 4.7-mg or two 9.4-mg implants were placed within the pectoral musculature on 3 occasions over the course of approximately 1.5 years. Plasma testosterone concentrations were measured by radioimmunoassay every 2 weeks for the first month after a new implant placement and then monthly thereafter. Testosterone concentrations remained low and aggressive behavior was decreased for a period of several months after implant placement. At necropsy of both birds, no adverse gross or histologic lesions were noted at the implantation sites in the pectoral musculature or within the gonadal tissue. Deslorelin acetate implants are a treatment modality to consider for mitigation of aggression in male domestic turkeys.
authors.forename: Christine M
authors.initials: CM
authors.lastname: Molter
authors.forename: Deidre K
authors.initials: DK
authors.lastname: Fontenot
authors.forename: Scott P
authors.initials: SP
authors.lastname: Terrell
mesh_terms: D000374:Aggression / Q000187:drug effects*; D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects*; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology*; D016729:Leuprolide / Q000008:administration & dosage / Q000494:pharmacology; D013739:Testosterone / Q000097:blood*; D017329:Triptorelin Pamoate / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D014422:Turkeys / Q000097:blood
chemical_list: D018931:Antineoplastic Agents, Hormonal; D004791:Enzyme Inhibitors; D017329:Triptorelin Pamoate; D013739:Testosterone; D016729:Leuprolide; C066438:deslorelin
keywords: Meleagris gallopavo; avian; deslorelin acetate; domestic turkey; intermale aggression; testosterone