title: Spirometric prediction equations and the relationship between metabolic syndrome and spirometric parameters from an island in Fujian, China.
abstract: BACKGROUND
  We investigated risk factors for decreased lung function among Chinese island residents (≥30 years) to determine the relationship between metabolic syndrome (MS) and decreased lung function.
  
  
  METHODS
  From October 17, 2011 to November 1, 2011, 2607 residents aged ≥30 years who lived on the Huangqi Peninsula of Fujian were enlisted by random cluster sampling. They completed a questionnaire designed according to the Burden of Obstructive Lung Disease (BOLD) questionnaire, and underwent physical examination, blood test, and lung function evaluation. We constructed spirometric prediction equations for forced vital capacity (FVC) and forced expiratory volume in one second (FEV1), determined the lower limits of normal for FVC, FEV1 and FEV1/FVC, and examined the relationship between lung function and MS.
  
  
  RESULTS
  Prediction equations for normal island residents were as follows: FVC (L) = -0.023 × age (years) + 0.042 × height (cm) + 0.641 × weight (kg) - 3.607 (males); FVC (L) = -0.017 × age (years) + 0.030 × height (cm) + 0.009 × weight (kg) - 1.741 (females); FEV1 (L) = -0.023 × age (years) + 0.040 × height (cm) + 0.010 × weight (kg) - 2.999 (males); FEV1 (L) = -0.017 × age (years) + 0.026 × height (cm) + 0.007 × weight (kg) -1.135 (females). The odds ratio for MS for increased risk of decreased FVC was 4.623 (95%CI =3.626-5.894, P<0.001), and for increased risk of decreased FEV1 was 3.043 (95%CI =2.447-3.785, P<0.001).
  
  
  CONCLUSIONS
  MS is a risk factor for decreased lung function in island residents ≥30 years old.
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Yu-Sheng
authors.initials: YS
authors.lastname: Chen
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Xiao-Qin
authors.initials: XQ
authors.lastname: Li
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Hong-Ru
authors.initials: HR
authors.lastname: Li
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Xiao-Li
authors.initials: XL
authors.lastname: Yu
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Feng-Feng
authors.initials: FF
authors.lastname: Lu
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Huang
authors.affiliation: Department of General Medicine, Fujian Provincial Hospital, Provincial Clinic College of Clinical Medicine of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Miao
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Gui-Qing
authors.initials: GQ
authors.lastname: Wang
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Lin
authors.affiliation: Department of Infectious Disease, Fujian Provincial Hospital, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Shuang-Qing
authors.initials: SQ
authors.lastname: Lian
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Yun-Hua
authors.initials: YH
authors.lastname: Lin
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Xiang-E
authors.initials: XE
authors.lastname: Zhang
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.affiliation: Department of Respiratory Medicine, Fujian Provincial Hospital, Provincial Clinic College of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D001774:Blood Chemical Analysis; D002681:China / Q000453:epidemiology; D015897:Comorbidity; D017281:Cost of Illness; D005260:Female; D005541:Forced Expiratory Volume / Q000502:physiology; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D008875:Middle Aged; D011237:Predictive Value of Tests; D012016:Reference Values; D012129:Respiratory Function Tests / Q000379:methods*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D013147:Spirometry / Q000379:methods*; D014797:Vital Capacity / Q000502:physiology
keywords: metabolic syndrome - prediction equation for pulmonary function - reference values for pulmonary function