title: Relationship between stent type and quality of life after percutaneous coronary intervention for acute myocardial infarction.
abstract: BACKGROUND
  Drug-eluting stents (DES) reduce restenosis, as compared with bare-metal stents (BMS); however, the relationship between stent type and health status is unknown. We examined whether stent type was associated with health status outcomes in patients undergoing percutaneous coronary intervention (PCI).
  
  
  RESULTS
  We evaluated 6- and 12-month health status in 2,694 patients with acute myocardial infarction (AMI) enrolled in the TRIUMPH and PREMIER registries who underwent PCI with DES (n = 1,361) or BMS (n = 1,333). Health status was assessed with the Seattle Angina Questionnaire, Medical Outcomes Study Short Form-12, and Patient Health Questionnaire depression scale. Propensity matching was performed to account for baseline differences in patient characteristics, resulting in a comparison cohort of 784 patients treated with DES and 784 patients treated with BMS. Both groups experienced significant improvements in health status at 6 and 12 months after PCI. Drug-eluting stent use was associated with a small improvement in Seattle Angina Questionnaire quality of life and functional limitation scores at 6 months (3.6 [95% CI 0.96-6.21], P = .007, and 3.8 [1.55-6.01], P < .001, respectively), but not at 12 months (2.3 [-0.46 to 5.03], P = .10, and 0.3 [-2.04 to 2.48], P = .85, respectively).
  
  
  CONCLUSIONS
  In patients with AMI undergoing PCI, DES use was associated with transient but unsustained health status benefits over 12 months after AMI.
authors.affiliation: Saint Luke's Mid America Heart Institute, Kansas City, MO; University of Missouri-Kansas City, Kansas City, MO. Electronic address: achhatriwalla@saint-lukes.org.
authors.forename: Adnan K
authors.initials: AK
authors.lastname: Chhatriwalla
authors.affiliation: University of Missouri-Kansas City, Kansas City, MO.
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Venkitachalam
authors.affiliation: Saint Luke's Mid America Heart Institute, Kansas City, MO.
authors.forename: Kevin F
authors.initials: KF
authors.lastname: Kennedy
authors.affiliation: Saint Louis University, St Louis, MO.
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Stolker
authors.affiliation: Saint Luke's Mid America Heart Institute, Kansas City, MO.
authors.forename: Philip G
authors.initials: PG
authors.lastname: Jones
authors.affiliation: Saint Luke's Mid America Heart Institute, Kansas City, MO; University of Missouri-Kansas City, Kansas City, MO.
authors.forename: David J
authors.initials: DJ
authors.lastname: Cohen
authors.affiliation: Saint Luke's Mid America Heart Institute, Kansas City, MO; University of Missouri-Kansas City, Kansas City, MO.
authors.forename: John A
authors.initials: JA
authors.lastname: Spertus
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000523:psychology / Q000601:surgery*; D062645:Percutaneous Coronary Intervention / Q000523:psychology*; D011184:Postoperative Period; D011379:Prognosis; D011474:Prosthesis Design; D011788:Quality of Life; D012042:Registries; D012189:Retrospective Studies; D015607:Stents; D013997:Time Factors