title: [New options for therapeutic revascularization in lower extremity limb ischemia linked to the diabetic foot syndrome by autologous stem cell transplantation].
abstract: Type 2 diabetes incidence is growing worldwide. It is in up to 50% cases linked with diabetic foot syndrome. This is associated with peripheral neuropathy and peripheral artery disease which increases risk of defects with impaired healing. Resulting high number of amputations has major influence on the quality of life and constitutes serious clinical issue. In recent years numerous clinical studies have shown positive effect of new treatment modality using regenerative potential of the autologous stem cells transplantation. This review tries to summarize existing results of therapeutic revascularization using stem cell and to outline mechanism of their action.
authors.forename: Jakub
authors.initials: J
authors.lastname: Svěcený
authors.forename: Eva
authors.initials: E
authors.lastname: Syková
authors.forename: Michal
authors.initials: M
authors.lastname: Tichý
authors.forename: Jiří
authors.initials: J
authors.lastname: Laštůvka
mesh_terms: D017719:Diabetic Foot / Q000601:surgery*; D006801:Humans; D033581:Stem Cell Transplantation / Q000379:methods*; D013577:Syndrome; D014656:Vascular Surgical Procedures / Q000379:methods*; D014945:Wound Healing
keywords: lower extremity limb ischemia - stem cells - critical limb ischemia - diabetes mellitus.