title: Ruthenium(II)-Catalyzed C-H Functionalizations with Allenes: Versatile Allenylations and Allylations.
abstract: Ruthenium(II)-catalyzed direct C-H functionalization of aromatic compounds with allenes was achieved under exceedingly mild reaction conditions to yield trisubstituted allenes. The reactions of N-methoxybenzamides proceeded smoothly in an isohypsic fashion at ambient temperature with high chemo- and regioselectivity, thereby providing a versatile means of accessing trisubstituted allenes. Detailed mechanistic studies were suggestive of a kinetically relevant C-H metalation step, which occurs by the assistance of a carboxylate moiety; this also set the stage for unprecedented C-H allylations with removable directing groups in a step-economical fashion.
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077 Göttingen (Germany).
authors.forename: Sachiyo
authors.initials: S
authors.lastname: Nakanowatari
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077 Göttingen (Germany). Lutz.Ackermann@chemie.uni-goettingen.de.
authors.forename: Lutz
authors.initials: L
authors.lastname: Ackermann
keywords: CH Activation; allenes; allenylation; amides; ruthenium