title: Sequential Oxidative α-Cyanation/Anti-Markovnikov Hydroalkoxylation of Allylamines.
abstract: Iron-catalyzed oxidative α-cyanations at tertiary allylamines in the allylic position are followed by anti-Markovnikov additions of alcohols across the vinylic CC double bonds of the initially generated α-amino nitriles. These consecutive reactions generate 2-amino-4-alkoxybutanenitriles from three reactants (allylamines, trimethylsilyl cyanide, and alcohols) in one reaction vessel at ambient temperature.
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität München , Butenandtstraße 5-13, 81377 München, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Wagner
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität München , Butenandtstraße 5-13, 81377 München, Germany.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Hampel
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität München , Butenandtstraße 5-13, 81377 München, Germany.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Zipse
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität München , Butenandtstraße 5-13, 81377 München, Germany.
authors.forename: Armin R
authors.initials: AR
authors.lastname: Ofial