title: Right ventricular and atrial functions in patients with nonischemic dilated cardiomyopathy.
abstract: OBJECTIVE
  The aim of this study was to assess the right ventricular and right atrial functions in patients with nonischemic dilated cardiomyopathy by novel echocardiographic measures.
  
  
  METHODS
  In all, 40 patients with nonischemic dilated cardiomyopathy and 26 healthy subjects were consecutively included. Left ventricular, right ventricular, and right atrial functions were assessed by tissue Doppler imaging and two-dimensional speckle tracking echocardiography. Right ventricular systolic dysfunction was accepted moderated to severe when tissue Doppler peak systolic velocity of tricuspid lateral annulus was < 9 cm/s.
  
  
  RESULTS
  In all, 18 of the 40 nonischemic dilated cardiomyopathy patients had peak systolic velocity of tricuspid lateral annulus < 9 cm/s and had significantly lower right ventricular free wall basal segment longitudinal strain, displacement, and right atrial functions assessed by speckle tracking echocardiography. Left ventricular tissue Doppler systolic velocity, global longitudinal and circumferential strain values were also lower in patients with moderated to severe right ventricular systolic dysfunction. Receiver operating characteristic analysis was preformed to assess the utility of right ventricular free wall basal segment longitudinal strain to predict right ventricular systolic dysfunction (peak systolic velocity < 9 cm/s). The cut off value for predicting right ventricular systolic dysfunction was - 20% with a sensitivity of 72%  and specificity of 73%  (AUC: 0.793; p = 0.002; 95% confidence interval: 0.645-0.941).
  
  
  CONCLUSIONS
  Right ventricular systolic function is impaired in nonischemic dilated cardiomyopathy patients. Two-dimensional speckle tracking echocardiography represents a promising noninvasive method to evaluate right ventricular and atrial function in this patient group.
authors.affiliation: Department of Cardiology, Marmara University Faculty of Medicine, Fevzi Cakmak Mahallesi, Muhsin Yazicioglu Caddesi, No: 10, Istanbul, Pendik, Turkey.
authors.forename: Kursat
authors.initials: K
authors.lastname: Tigen
authors.affiliation: Department of Cardiology, Acibadem University Faculty of Medicine, Istanbul, Turkey.
authors.forename: Tansu
authors.initials: T
authors.lastname: Karaahmet
authors.affiliation: Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, Turkey.
authors.forename: Cihan
authors.initials: C
authors.lastname: Dundar
authors.affiliation: Department of Cardiology, Marmara University Faculty of Medicine, Fevzi Cakmak Mahallesi, Muhsin Yazicioglu Caddesi, No: 10, Istanbul, Pendik, Turkey.
authors.forename: Altug
authors.initials: A
authors.lastname: Cincin
authors.affiliation: Department of Cardiology, Marmara University Faculty of Medicine, Fevzi Cakmak Mahallesi, Muhsin Yazicioglu Caddesi, No: 10, Istanbul, Pendik, Turkey.
authors.forename: Beste
authors.initials: B
authors.lastname: Ozben
authors.affiliation: Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Guler
authors.affiliation: Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Gurel
authors.affiliation: Department of Cardiology, Marmara University Faculty of Medicine, Fevzi Cakmak Mahallesi, Muhsin Yazicioglu Caddesi, No: 10, Istanbul, Pendik, Turkey. drsunbul@yahoo.com.tr.
authors.forename: Murat
authors.initials: M
authors.lastname: Sunbul
authors.affiliation: Department of Cardiology, Marmara University Faculty of Medicine, Fevzi Cakmak Mahallesi, Muhsin Yazicioglu Caddesi, No: 10, Istanbul, Pendik, Turkey.
authors.forename: Yelda
authors.initials: Y
authors.lastname: Basaran
mesh_terms: D000328:Adult; D016280:Atrial Function, Right; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004452:Echocardiography / Q000379:methods*; D054459:Elasticity Imaging Techniques / Q000379:methods; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology*; D016278:Ventricular Function, Right
keywords: Nonischemic dilated cardiomyopathy; Right atrial function; Right ventricular function; Speckle tracking echocardiography; Tissue Doppler imaging