title: A case of relapsing-remitting tumour-like inflammation of the central nervous system.
abstract: The case of a 37-year-old woman suffering from a relapsing-remitting tumefactive inflammatory disease of the central nervous system (CNS) is described. The patient had four severe relapses over eight years, and was treated with steroids, immunosuppression and plasma-exchange with modest benefit. No magnetic resonance imaging or cerebrospinal spinal fluid findings suggestive of multiple sclerosis emerged during the eight-year follow-up. 'Relapsing-remitting tumefactive inflammation' seems to have the features of a distinct inflammatory CNS disease.
authors.affiliation: The Multiple Sclerosis Centre - Veneto Region (CeSMuV), Department of Neurosciences DNS, University Hospital of Padova, Italy silvia.miante@gmail.com.
authors.forename: Silvia
authors.initials: S
authors.lastname: Miante
authors.affiliation: The Multiple Sclerosis Centre - Veneto Region (CeSMuV), Department of Neurosciences DNS, University Hospital of Padova, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Perini
authors.affiliation: The Multiple Sclerosis Centre - Veneto Region (CeSMuV), Department of Neurosciences DNS, University Hospital of Padova, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Rinaldi
authors.affiliation: The Multiple Sclerosis Centre - Veneto Region (CeSMuV), Department of Neurosciences DNS, University Hospital of Padova, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Gallo
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000473:pathology*; D003711:Demyelinating Diseases / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000473:pathology*; D004660:Encephalitis / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006423:Hemianopsia / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D012008:Recurrence; D013577:Syndrome
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone
keywords: Tumour-like lesions; central nervous system; inflammation; multiple sclerosis; relapsing–remitting