title: The molecular circuit of steroid signalling in plants.
abstract: Steroid hormones are key regulators of growth and physiology in both plants and animals. The plant steroid hormones known as brassinosteroids (BRs) are essential for a wide range of developmental processes throughout the life cycle. In contrast with animal steroid hormones, which act mostly through nuclear receptors, BRs act through a cell-surface receptor kinase. The BR signal transduction pathway from the cell-surface receptor to nuclear gene expression has been elucidated in great molecular detail, and thus serves as a paradigm for receptor kinase signalling in plants. Furthermore, several mechanisms of signal integration have been identified that explain how BRs and other hormonal and environmental signals co-regulate specific developmental outputs in a synergistic or antagonistic manner.
authors.affiliation: Carnegie Institution for Science, 260 Panama Street, Stanford, CA 94305, U.S.A.
authors.forename: Thomas
authors.initials: T
authors.lastname: Hartwig
authors.affiliation: Carnegie Institution for Science, 260 Panama Street, Stanford, CA 94305, U.S.A. zywang24@stanford.edu.
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Wang
mesh_terms: D060406:Brassinosteroids / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D002467:Cell Nucleus / Q000235:genetics / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D010937:Plant Growth Regulators / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D060406:Brassinosteroids; D010937:Plant Growth Regulators
keywords: auxin; brassinosteroids; cross-talk; gibberelic acid; phytochrome; phytohormones; signal integration; signal transduction