title: Cryptococcus laurentii fungaemia in a cervical cancer patient.
abstract: Infections caused by emerging Cryptococcus non-neoformans species are being reported with increasingly frequency. Here, we present a case of fungaemia by Cryptococcus laurentii in a woman receiving aggressive immunosuppressive therapy for cervical neoplasia. Three venous blood samples were aseptically collected on consecutive days and C. laurentii was isolated and identified through phenotypic and molecular methods. After central venous catheter removal and appropriate antifungal therapy, the patient showed significant improvement and blood culture became negative. Thus, patients following immunosuppressive therapies and using invasive medical devices are at risk of C. laurentii blood infections.
authors.affiliation: Departamento de Micologia, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
authors.forename: Rejane Pereira
authors.initials: RP
authors.lastname: Neves
authors.affiliation: Departamento de Medicina Tropical, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
authors.forename: Reginaldo Gonçalves de
authors.initials: RG
authors.lastname: Lima Neto
authors.affiliation: Departamento de Micologia, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
authors.forename: Melyna Chaves
authors.initials: MC
authors.lastname: Leite
authors.affiliation: Departamento de Micologia, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
authors.forename: Vanessa Karina Alves da
authors.initials: VK
authors.lastname: Silva
authors.affiliation: Departamento de Micologia, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
authors.forename: Franz de Assis Graciano dos
authors.initials: Fde A
authors.lastname: Santos
authors.affiliation: Departamento de Ciências Farmacêuticas, Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil. Electronic address: daniellemacedo28@gmail.com.
authors.forename: Danielle Patrícia Cerqueira
authors.initials: DP
authors.lastname: Macêdo
mesh_terms: D000328:Adult; D003453:Cryptococcosis / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*; D003454:Cryptococcus / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D016469:Fungemia / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000382:microbiology; D002578:Uterine Cervical Dysplasia / Q000150:complications* / Q000382:microbiology
keywords: Cancer; Cryptococcus laurentii; Fungaemia