title: Vaccines to prevent pneumonia in children - a developing country perspective.
abstract: Pneumonia accounted for 15% of the 6.3 million deaths among children younger than five years in 2013, a total of approximately 935,000 deaths worldwide. Routine vaccination against common childhood illnesses has been identified as one of the most cost-effective strategies to prevent death from pneumonia. Vaccine-preventable or potentially preventable diseases commonly linked with respiratory tract infections include Streptococcus pneumoniae, Haemophilus influenza type-b (Hib), pertussis, influenza, measles, and tuberculosis. Although here have been great strides in the development and administration of effective vaccines, the countries that carry the largest disease burdens still struggle to vaccinate their children and newer conjugated vaccines remain out of reach for many. The Global Vaccine Action Plan (GVAP) has identified priority areas for innovation in research in all aspects of immunisation development and delivery to ensure equitable access to vaccines for all.
authors.affiliation: KEMRI Wellcome Trust Research Programme, Department of Public Health Research, Health Services Unit, Nairobi, Kenya. Electronic address: joliwa@kemri-wellcome.org.
authors.forename: Jacquie N
authors.initials: JN
authors.lastname: Oliwa
authors.affiliation: Marie Bashir Institute for Infectious Diseases and Biosecurity and The Children's Hospital at Westmead, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
authors.forename: Ben J
authors.initials: BJ
authors.lastname: Marais
mesh_terms: D001500:BCG Vaccine / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D006192:Haemophilus Infections / Q000517:prevention & control; D018073:Haemophilus Vaccines / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007252:Influenza Vaccines / Q000627:therapeutic use; D007251:Influenza, Human / Q000517:prevention & control; D008457:Measles / Q000517:prevention & control; D008458:Measles Vaccine / Q000627:therapeutic use; D010567:Pertussis Vaccine / Q000627:therapeutic use; D022242:Pneumococcal Vaccines / Q000627:therapeutic use; D011014:Pneumonia / Q000517:prevention & control*; D011018:Pneumonia, Pneumococcal / Q000517:prevention & control; D014397:Tuberculosis, Pulmonary / Q000517:prevention & control; D014612:Vaccines / Q000627:therapeutic use*; D014917:Whooping Cough / Q000517:prevention & control
chemical_list: D001500:BCG Vaccine; D018073:Haemophilus Vaccines; D007252:Influenza Vaccines; D008458:Measles Vaccine; D010567:Pertussis Vaccine; D022242:Pneumococcal Vaccines; D014612:Vaccines
keywords: Children; Developing countries; Pneumonia; Vaccines