title: Fraser syndrome with laryngeal webs: Report of two cases and a review of the literature.
abstract: Fraser syndrome is a rare genetic disorder characterized by cryptophthalmos, syndactyly and laryngeal atresia. Although laryngeal webs occur uncommonly, they are the main cause of death in the first week of life in these patients. In this paper, we report two cases of Fraser syndrome with laryngeal webs. One of them was a twelve-year-old girl, primarily diagnosed with a supraglottic laryngeal web. In the course of treatment, a second web was also identified at the level of vocal cords, which is to our knowledge the first case of Fraser syndrome with two laryngeal webs in different levels.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Iran University of Medical Sciences, Tehran, Iran. Electronic address: izadimd@yahoo.com.
authors.forename: Farzad
authors.initials: F
authors.lastname: Izadi
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Iran University of Medical Sciences, Tehran, Iran. Electronic address: aslanahmadi8931@gmail.com.
authors.forename: Aslan
authors.initials: A
authors.lastname: Ahmadi
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Hosna
authors.initials: H
authors.lastname: Zobairy
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Sepideh
authors.initials: S
authors.lastname: Bakhti
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Hengameh
authors.initials: H
authors.lastname: Hirbod
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Iran University of Medical Sciences, Tehran, Iran. Electronic address: mahdisafdarian@gmail.com.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Safdarian
mesh_terms: D002648:Child; D005260:Female; D058497:Fraser Syndrome / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000209:etiology; D013576:Syndactyly / Q000209:etiology; D014827:Vocal Cords
keywords: CO(2) laser; Fraser syndrome; Laryngeal stenosis; Laryngeal web