title: EX-PRESS Glaucoma Filtration Device: efficacy, safety, and predictability.
abstract: Trabeculectomy has been the traditional primary surgical therapy for open-angle glaucoma. While trabeculectomy is effective in lowering intraocular pressure, complications associated with the procedure have motivated the development of alternative techniques and devices, including the EX-PRESS Glaucoma Filtration Device. This review describes the efficacy, safety, complication rates, and potential advantages and disadvantages of the EX-PRESS Glaucoma Filtration Device. EX-PRESS implantation is technically simpler compared with that of trabeculectomy, with fewer surgical steps. Vision recovery has been more rapid after EX-PRESS implantation compared with trabeculectomy. Intraocular pressure variation is lower during the early postoperative period, indicating a more predictable procedure. While efficacy of the EX-PRESS implant has been comparable to trabeculectomy, postoperative complications appear less common after EX-PRESS implantation compared with trabeculectomy. The EX-PRESS Glaucoma Filtration Device appears to be safe and effective in the surgical management of open-angle glaucoma.
authors.affiliation: Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA, USA.
authors.forename: Jessica E
authors.initials: JE
authors.lastname: Chan
authors.affiliation: Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA, USA.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Netland
keywords: glaucoma drainage implant; mitomycin C; surgery; trabeculectomy