title: Intrapartum electrocardiogram alteration in fetuses with congenital heart disease: a case-control study.
abstract: OBJECTIVE
  To assess if the fetal electrocardiogram especially ST segment is modified by congenital heart diseases: modifications in frequencies of the different ST events and modifications in signal quality.
  
  
  METHODS
  A retrospective case-control study, comparing frequencies of the different ST events and the quality of the signal between fetuses with congenital heart diseases and fetuses without congenital heart disease. From 2000 to 2011, fifty-eight fetuses with congenital heart disease had their heart rate recording using a STAN device during labor. Control group was fetuses who were born just before a case and had a STAN as a second line for intrapartum surveillance. Cases and controls were matched on parity, gestational age at birth, presence of growth restriction and umbilical artery pH. Frequencies of the different ST event and quality of the signal were first analyzed for the global labor recording, and then separately for the first and the second phase of labor.
  
  
  RESULTS
  No statistically significant difference in ST event frequencies between fetuses with congenital heart disease and the control group was found. Regarding the quality of the signal, 11.49% (±18.82) of recording time is a signal loss for fetus with congenital heart disease whereas only 5.18% (±10.67) for the control group (p=0.028).
  
  
  CONCLUSIONS
  This is the first study investigating for intrapartum electrocardiogram modification in fetus with congenital heart disease. Congenital heart diseases do not modify frequencies of ST events.
authors.affiliation: Hospices civils de Lyon, Hôpital Femme Mère Enfant, Department of Obstetrics and Gynecology, 59 boulevard Pinel, Bron Cedex F69677, France; University Lyon 1, Faculté de Médecine Lyon Est, 8 avenue Rockefeller, 69003 Lyon, France.
authors.forename: Estelle
authors.initials: E
authors.lastname: Gay
authors.affiliation: Hospices civils de Lyon, Hôpital Femme Mère Enfant, Department of Obstetrics and Gynecology, 59 boulevard Pinel, Bron Cedex F69677, France.
authors.forename: Géraldine
authors.initials: G
authors.lastname: Bornallet
authors.affiliation: Hospices civils de Lyon, Hôpital Femme Mère Enfant, Department of Obstetrics and Gynecology, 59 boulevard Pinel, Bron Cedex F69677, France; University Lyon 1, Faculté de Médecine Lyon Est, 8 avenue Rockefeller, 69003 Lyon, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Gaucherand
authors.affiliation: Hospices civils de Lyon, Hôpital Femme Mère Enfant, Department of Obstetrics and Gynecology, 59 boulevard Pinel, Bron Cedex F69677, France; University Lyon 1, Faculté de Médecine Lyon Est, 8 avenue Rockefeller, 69003 Lyon, France. Electronic address: muriel.doret@chu-lyon.fr.
authors.forename: Muriel
authors.initials: M
authors.lastname: Doret
mesh_terms: D016022:Case-Control Studies; D004562:Electrocardiography; D005260:Female; D005315:Fetal Diseases / Q000503:physiopathology*; D005323:Fetal Monitoring; D006331:Heart Diseases / Q000151:congenital* / Q000503:physiopathology*; D006340:Heart Rate, Fetal; D006801:Humans; D007743:Labor, Obstetric; D008297:Male; D036801:Parturition; D011247:Pregnancy; D012189:Retrospective Studies; D059629:Signal-To-Noise Ratio
keywords: Congenital heart disease; Electrocardiogram; Fetus; Intrapartum; STAN