title: [Lung cancer: Stereotactic body radiation therapy and surgery].
abstract: Stereotactic body radiation therapy for lung cancer is now well established for patients who are not eligible to surgery. These patients can benefit from a curative treatment, which is a new therapeutic indication. Protocols are effective and well tolerated even for the most fragile patients. Three randomized trials comparing stereotactic body radiation therapy and surgery failed due to poor accrual. However, taking into account the favourable available data, the choice of stereotactic body radiation therapy in first intention arises. The treatment decision has to be discussed in a multidisciplinary way, while considering the opinion of the patient, who must be clearly informed about the principle of both therapeutic options.
authors.affiliation: Département universitaire de radiothérapie, Unicancer, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67065 Strasbourg cedex, France; Laboratoire EA 3430, fédération de médecine translationnelle de Strasbourg (FMTS), université de Strasbourg, 67062 Strasbourg, France. Electronic address: dantoni@strasbourg.unicancer.fr.
authors.forename: D
authors.initials: D
authors.lastname: Antoni
authors.affiliation: Département universitaire de radiothérapie, Unicancer, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67065 Strasbourg cedex, France.
authors.forename: I
authors.initials: I
authors.lastname: Srour
authors.affiliation: Département de radiothérapie oncologique, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France; EA 3738, université Claude-Bernard Lyon-1, domaine Rockefeller, 8, avenue Rockefeller, 69373 Lyon cedex 08, France.
authors.forename: F
authors.initials: F
authors.lastname: Mornex
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008207:Lymphatic Metastasis; D016634:Radiosurgery / Q000592:standards; D016032:Randomized Controlled Trials as Topic
keywords: Cancer du poumon; Chirurgie; Lung cancer; Radiothérapie en conditions stéréotaxiques; Stereotactic ablative radiotherapy; Surgery