title: Giant liposarcoma of the esophagus: A case report.
abstract: Liposarcomas rarely develop in the aerodigestive tract. Here, we present a primary esophageal liposarcoma that was discovered between the T3 and T7 levels of the esophagus during right pleural exploration of a 51-year-old male patient. The patient had presented with non-specific symptoms, including progressive dysphagia over the previous 6 mo, without complaints of chest or epigastric pain, regurgitation, or weight loss. A radical three-hole esophagectomy was performed. The tumor was extremely large (14 cm × 7.0 cm × 6.5 cm), but completely encapsulated. Upon histological examination, the tumor was diagnosed as a giant, well-differentiated esophageal liposarcoma with a dedifferentiated component. Non-specific radiological and endoscopic results during the clinical work-up delayed diagnosis until post-operative histology was performed. In this report, the clinical, radiological and endoscopic diagnostic challenges specific to the case are discussed, as well as the surgical and pathological findings.
authors.affiliation: Zhi-Chao Lin, Department of Thoracic Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen 529030, Guangdong Province, China.
authors.forename: Zhi-Chao
authors.initials: ZC
authors.lastname: Lin
authors.affiliation: Zhi-Chao Lin, Department of Thoracic Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen 529030, Guangdong Province, China.
authors.forename: Xiang-Zhen
authors.initials: XZ
authors.lastname: Chang
authors.affiliation: Zhi-Chao Lin, Department of Thoracic Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen 529030, Guangdong Province, China.
authors.forename: Xiu-Fang
authors.initials: XF
authors.lastname: Huang
authors.affiliation: Zhi-Chao Lin, Department of Thoracic Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen 529030, Guangdong Province, China.
authors.forename: Chun-Lai
authors.initials: CL
authors.lastname: Zhang
authors.affiliation: Zhi-Chao Lin, Department of Thoracic Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen 529030, Guangdong Province, China.
authors.forename: Geng-Sheng
authors.initials: GS
authors.lastname: Yu
authors.affiliation: Zhi-Chao Lin, Department of Thoracic Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen 529030, Guangdong Province, China.
authors.forename: Shuo-Yun
authors.initials: SY
authors.lastname: Wu
authors.affiliation: Zhi-Chao Lin, Department of Thoracic Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen 529030, Guangdong Province, China.
authors.forename: Min
authors.initials: M
authors.lastname: Ye
authors.affiliation: Zhi-Chao Lin, Department of Thoracic Surgery, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen 529030, Guangdong Province, China.
authors.forename: Jian-Xing
authors.initials: JX
authors.lastname: He
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D002454:Cell Differentiation; D004938:Esophageal Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016629:Esophagectomy; D004945:Esophagoscopy; D006801:Humans; D007150:Immunohistochemistry; D008080:Liposarcoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D047368:Tumor Burden
chemical_list: D014408:Biomarkers, Tumor
keywords: Achalasia; Esophagectomy; Esophagus; Liposarcoma