title: Management of Gingival Overgrowth in a Cardiac Transplant Patient Using Laser-Assisted Gingivectomy/Gingivoplasty.
abstract: Drug-induced gingival overgrowth (DIGO) is an oral clinical manifestation associated with certain medications such as immunosuppressants that are administered to organ transplant patients to prevent graft rejection. In patients with cardiac transplants, management of DIGO is critical. In such patients, plaque biofilm accumulation at the gingival interface might be detrimental as it may lead to transient bacteremia as well as systemic inflammation resulting in thromboembolic events. This case report describes the management of DIGO in a cardiac transplant recipient by change of immunosuppressant medication, non-surgical periodontal therapy and laser-assisted gingivectomy.
authors.forename: Abhiram
authors.initials: A
authors.lastname: Maddi
authors.forename: Leela Subhashini
authors.initials: LS
authors.lastname: Alluri
authors.forename: Sebastian G
authors.initials: SG
authors.lastname: Ciancio
mesh_terms: D000328:Adult; D016572:Cyclosporine / Q000009:adverse effects; D012534:Dental Scaling / Q000379:methods; D005500:Follow-Up Studies; D019214:Gingival Overgrowth / Q000139:chemically induced / Q000601:surgery*; D005890:Gingivectomy / Q000379:methods*; D005893:Gingivoplasty / Q000379:methods*; D016027:Heart Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D053685:Laser Therapy / Q000379:methods*; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D008297:Male; D009910:Oral Hygiene / Q000193:education; D016745:Root Planing / Q000379:methods; D020123:Sirolimus / Q000627:therapeutic use
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D020123:Sirolimus