title: Enantioselective Steglich Rearrangement of Oxindole Derivatives by Easily Accessible Chiral N,N-4-(Dimethylamino)pyridine Derivatives.
abstract: Chiral N,N-4-(dimethylamino)pyridine (DMAP) derivatives, which can be readily prepared by the Ugi multicomponent reaction in a one-pot manner, have been efficiently applied to the enantioselective Steglich rearrangement of oxindole derivatives to give the desired products bearing a quaternary carbon center in high yield (>98% yield) and with high enantioselectivity (up to 99:1 er).
authors.affiliation: Division of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University , 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Mandai
authors.affiliation: Division of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University , 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors.forename: Takuma
authors.initials: T
authors.lastname: Fujiwara
authors.affiliation: Division of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University , 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors.forename: Katsuaki
authors.initials: K
authors.lastname: Noda
authors.affiliation: Division of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University , 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Fujii
authors.affiliation: Division of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University , 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Mitsudo
authors.affiliation: Faculty of Engineering, Department of Chemistry and Bioengineering, Iwate University, Morioka , Iwate 020-8551, Japan.
authors.forename: Toshinobu
authors.initials: T
authors.lastname: Korenaga
authors.affiliation: Division of Applied Chemistry, Graduate School of Natural Science and Technology, Okayama University , 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.|Research Center of New Functional Materials for Energy Production, Storage and Transport, Okayama University , 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.|Japan Science and Technology Agency, ACT-C , 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.
authors.forename: Seiji
authors.initials: S
authors.lastname: Suga