title: [Conservative and surgical treatment of patients with resistant epilepsy].
abstract: OBJECTIVE
  To optimize drug treatment in early (6 months) and late (up to 3 years) stages of postoperative period and to study its efficacy.
  
  
  METHODS
  There were selected 72 patients with resistant epilepsy and epileptic encephalopathy symptoms from 467 patients operated for epilepsy.
  
  
  RESULTS
  By the end of a 3-year follow-up observation, we found the reduction in seizure frequency and seizure control in 66.3% of patients; regression of EEG paroxysmal activity in 56.8% and reduction in mental disorder symptoms (anxiety and depression) in 12.7%.
  
  
  CONCLUSIONS
  The data obtained substantiate the necessity to optimize antiepileptic and pathogenetic drug treatment of patients with resistant epilepsy and encephalopathy symptoms during the 3-year postoperative period.
authors.affiliation: Bekhterev St. Petersburg Psychoneurological Research Institute, St. Petersburg.
authors.forename: S A
authors.initials: SA
authors.lastname: Gromov
authors.affiliation: Polenov Russian Neurosurgical Research Institute, St. Petersburg.
authors.forename: N E
authors.initials: NE
authors.lastname: Ivanova
authors.affiliation: Polenov Russian Neurosurgical Research Institute, St. Petersburg.
authors.forename: V R
authors.initials: VR
authors.lastname: Kasumov
authors.affiliation: Polenov Russian Neurosurgical Research Institute, St. Petersburg.
authors.forename: E A
authors.initials: EA
authors.lastname: Terenkal
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D004351:Drug Resistance; D004569:Electroencephalography; D004827:Epilepsy / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D000927:Anticonvulsants