title: Initial factors affecting the clinical outcome after successful recanalization via MR-based mechanical thrombectomy in patients with acute ischemic stroke due to basilar artery occlusion.
abstract: OBJECTIVE
  To determine the initial factors, including patient characteristics, stroke etiology and severity, time factors, and imaging findings, that could affect the clinical outcome of patients with acute ischemic stroke (AIS) caused by basilar artery occlusion (BAO) where successful recanalization was achieved via mechanical thrombectomy.
  
  
  METHODS
  Between March 2011 and December 2014, 35 patients with AIS caused by BAO received MRI/MR angiography-based mechanical thrombectomies, and recanalization was achieved with a Thrombolysis In Cerebral Infarction score of >2b. The patients were divided into a good outcome group (n=19), defined as those with a modified Rankin Scale (mRS) score of 0-2 at 3 months after stroke onset, and a poor outcome group (n=16), defined as a mRS score of 3-6. The differences between the groups were analyzed.
  
  
  RESULTS
  Initial National Institutes of Health Stroke Scale (NIHSS) score (good vs poor: 17.9±8.9 vs 27.6±8.5, p=0.003), posterior circulation Acute Stroke Prognosis Early CT Score (pc-ASPECTS) based on initial diffusion-weighted images (DWI) (good vs poor: 7.8±1.6 vs 5.4±1.8, p=0.001), pc-ASPECTS based on contrast staining on the post-thrombectomy control CT (good vs poor: 9.2±1.5 vs 6.3±2.2, p<0.001), and presence of contrast staining in the brainstem on that CT (good vs poor: 15.8% vs 81.6%, p<0.001) were significantly different between the groups.
  
  
  CONCLUSIONS
  Patients with AIS caused by BAO with a lower initial NIHSS score, fewer lesions on initial DWI, and less contrast staining on the post-thrombectomy control CT have higher probabilities of a good clinical outcome after successful recanalization via a mechanical thrombectomy.
authors.affiliation: Department of Neurology, Gyeongsang National University, School of Medicine, Jinju, Korea Gyeongnam Regional Cardiocerebrovascular Disease Center, Jinju, Korea.
authors.forename: Seungnam
authors.initials: S
authors.lastname: Son
authors.affiliation: Department of Neurology, Kyungpook National University, School of Medicine, Daegu, Korea Cerebrovascular Center, Kyungpook National University Hospital, Daegu, Korea.
authors.forename: Yong-Won
authors.initials: YW
authors.lastname: Kim
authors.affiliation: Gyeongnam Regional Cardiocerebrovascular Disease Center, Jinju, Korea Department of Rehabilitation Medicine, Gyeongsang National University, School of Medicine, Jinju, Korea.
authors.forename: Min Kyun
authors.initials: MK
authors.lastname: Oh
authors.affiliation: Department of Neurology, Gyeongsang National University, School of Medicine, Jinju, Korea Gyeongnam Regional Cardiocerebrovascular Disease Center, Jinju, Korea.
authors.forename: Soo-Kyoung
authors.initials: SK
authors.lastname: Kim
authors.affiliation: Department of Neurology, Gyeongsang National University, School of Medicine, Jinju, Korea.
authors.forename: Ki-Jong
authors.initials: KJ
authors.lastname: Park
authors.affiliation: Department of Neurology, Gyeongsang National University, School of Medicine, Jinju, Korea Gyeongnam Regional Cardiocerebrovascular Disease Center, Jinju, Korea.
authors.forename: Nack-Cheon
authors.initials: NC
authors.lastname: Choi
authors.affiliation: Department of Neurology, Gyeongsang National University, School of Medicine, Jinju, Korea.
authors.forename: Oh-Young
authors.initials: OY
authors.lastname: Kwon
authors.affiliation: Department of Neurology, Gyeongsang National University, School of Medicine, Jinju, Korea Gyeongnam Regional Cardiocerebrovascular Disease Center, Jinju, Korea.
authors.forename: Byeong Hoon
authors.initials: BH
authors.lastname: Lim
authors.affiliation: Department of Radiology, Gyeongsang National University, School of Medicine, Jinju, Korea.
authors.forename: Ho Cheol
authors.initials: HC
authors.lastname: Choi
authors.affiliation: Gyeongnam Regional Cardiocerebrovascular Disease Center, Jinju, Korea Department of Radiology, Gyeongsang National University, School of Medicine, Jinju, Korea.
authors.forename: Dae Seob
authors.initials: DS
authors.lastname: Choi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D061185:Mechanical Thrombolysis / Q000379:methods*; D008875:Middle Aged; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging / Q000628:therapy*
keywords: MRI; Stroke; Thrombectomy