title: Stent Maps--Comparative Visualization for the Prediction of Adverse Events of Transcatheter Aortic Valve Implantations.
abstract: Transcatheter aortic valve implantation (TAVI) is a minimally-invasive method for the treatment of aortic valve stenosis in patients with high surgical risk. Despite the success of TAVI, side effects such as paravalvular leakages can occur postoperatively. The goal of this project is to quantitatively analyze the co-occurrence of this complication and several potential risk factors such as stent shape after implantation, implantation height, amount and distribution of calcifications, and contact forces between stent and surrounding structure. In this paper, we present a two-dimensional visualization (stent maps), which allows (1) to comprehensively display all these aspects from CT data and mechanical simulation results and (2) to compare different datasets to identify patterns that are typical for adverse effects. The area of a stent map represents the surface area of the implanted stent - virtually straightened and uncoiled. Several properties of interest, like radial forces or stent compression, are displayed in this stent map in a heatmap-like fashion. Important anatomical landmarks and calcifications are plotted to show their spatial relation to the stent and possible correlations with the color-coded parameters. To provide comparability, the maps of different patient datasets are spatially adjusted according to a corresponding anatomical landmark. Also, stent maps summarizing the characteristics of different populations (e.g. with or without side effects) can be generated. Up to this point several interesting patterns have been observed with our technique, which remained hidden when examining the raw CT data or 3D visualizations of the same data. One example are obvious radial force maxima between the right and non-coronary valve leaflet occurring mainly in cases without leakages. These observations confirm the usefulness of our approach and give starting points for new hypotheses and further analyses. Because of its reduced dimensionality, the stent map data is an appropriate input for statistical group evaluation and machine learning methods.
authors.forename: Silvia
authors.initials: S
authors.lastname: Born
authors.forename: Simon H
authors.initials: SH
authors.lastname: Sündermann
authors.forename: Christoph
authors.initials: C
authors.lastname: Russ
authors.forename: Raoul
authors.initials: R
authors.lastname: Hopf
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Ruiz
authors.forename: Volkmar
authors.initials: V
authors.lastname: Falk
authors.forename: Michael
authors.initials: M
authors.lastname: Gessat
mesh_terms: D003196:Computer Graphics; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008955:Models, Cardiovascular; D015233:Models, Statistical; D015607:Stents / Q000009:adverse effects*; D065467:Transcatheter Aortic Valve Replacement / Q000009:adverse effects*