title: Catalytic Enantioselective 1,4-Iodofunctionalizations of Conjugated Dienes.
abstract: The first catalytic enantioselective 1,4-iodofunctionalizations of conjugated dienes have been developed. Starting from β,γ,δ,ε-unsaturated oximes and 4-Ns hydrazones, these N-iodosuccinimide-mediated reactions are catalyzed by newly modified tertiary aminothiourea derivatives and furnish Δ(2)-isoxazoline and Δ(2)-pyrazoline derivatives, respectively, containing an (E)-allyl iodide group at the quaternary stereogenic center generally in high yield and with excellent enantioselectivity (up to 98.5:1.5 er).
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science , Bangalore 560012, India.
authors.forename: Chandra Bhushan
authors.initials: CB
authors.lastname: Tripathi
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science , Bangalore 560012, India.
authors.forename: Santanu
authors.initials: S
authors.lastname: Mukherjee