title: Comparison of Efficacy and Cost of Iodine Impregnated Drape vs. Standard Drape in Cardiac Surgery: Study in 5100 Patients.
abstract: We sought to examine the efficacy in preventing surgical site infection (SSI) in cardiac surgery, using two different incise drapes (not iodine-impregnated and iodine-impregnated). A cost analysis was also considered. Between January 2008 and March 2015, 5100 consecutive cardiac surgery patients, who underwent surgery in our Institute, were prospectively collected. A total of 3320 patients received a standard not iodine-impregnated steri-drape (group A), and 1780 patients received Ioban(®) 2 drape (group B). We investigated, by a propensity matched analysis, whether the use of standard incise drape or iodine-impregnated drape would impact upon SSI rate. Totally, 808 patients for each group were matched for the available risk factors. Overall incidence of SSI was significantly higher in group A (6.5 versus 1.9 %) (p = 0.001). Superficial SSI incidence was significantly higher in group A (5.1 vs 1.6 %) (p = 0.002). Deep SSI resulted higher in group A (1.4 %) than in group B (0.4 %), although not significantly (p = 0.11). Consequently, the need for vacuum-assisted closure (VAC) therapy use resulted 4.3 % in group A versus 1.2 % in group B (p = 0.001). Overall costs for groups A and B were 12.494.912 € and 11.721.417 €, respectively. The Ioban(®) 2 offered totally 773.495 € cost savings compared to standard steri-drape. Ioban 2 drape assured a significantly lower incidence of SSI. Additionally, Ioban(®) 2 drape proved to be cost-effective in cardiac surgery.
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Jonida
authors.initials: J
authors.lastname: Bejko
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Tarzia
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Carrozzini
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Gallo
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Bortolussi
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Marina
authors.initials: M
authors.lastname: Comisso
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Testolin
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Cosimo
authors.initials: C
authors.lastname: Guglielmi
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: De Franceschi
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Bianco
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy.
authors.forename: Gino
authors.initials: G
authors.lastname: Gerosa
authors.affiliation: Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua, Via Giustiniani 2, 35100, Padova, Italy. tbottio@gmail.com.
authors.forename: Tomaso
authors.initials: T
authors.lastname: Bottio
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures / Q000295:instrumentation*; D003362:Cost-Benefit Analysis; D004526:Efficiency; D004867:Equipment Design; D005260:Female; D006801:Humans; D007455:Iodine; D008297:Male; D054843:Negative-Pressure Wound Therapy; D011182:Postoperative Care; D011300:Preoperative Care; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D058636:Surgical Drapes / Q000191:economics; D013529:Surgical Wound Dehiscence; D013530:Surgical Wound Infection / Q000517:prevention & control; D014945:Wound Healing
chemical_list: D007455:Iodine
keywords: Dehiscence; Healing; Pre-operative and post-operative care; Wound closure; Wound infection