title: Particulated articular cartilage for symptomatic chondral defects of the knee.
abstract: The treatment of focal cartilage defects in the knee remains a challenging clinical problem. One relatively new unique treatment option is particulated articular cartilage, which includes autograft and off-the-shelf allogeneic juvenile grafts. The use of particulated cartilage has the advantage of being a single-stage procedure. In the case of autograft, it is cost efficient, while in the juvenile allograft form, it may have increased proliferative and restorative potentials. Laboratory and clinical data are limited for particulated cartilage grafts; however, there are promising histologic and clinical outcomes. This review provides a summary of the indications, surgical technique, and most up-to-date research on particulated cartilage for the repair of symptomatic chondral defects in the knee.
authors.affiliation: Division of Sports Medicine, Rush University Medical Center, Chicago, IL, USA. jriboh@gmail.com.
authors.forename: Jonathan C
authors.initials: JC
authors.lastname: Riboh
authors.affiliation: Division of Sports Medicine, Rush University Medical Center, Chicago, IL, USA.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Cole
authors.affiliation: Cartilage Restoration Center of Indiana, Greenwood, IN, USA.
authors.forename: Jack
authors.initials: J
authors.lastname: Farr
keywords: Cartilage repair; Cartilage transplant; Juvenile cartilage; Particulated cartilage; Tissue regeneration