title: Artery calcification, osteoporosis, and plasma adiponectin levels in Chinese elderly.
abstract: OBJECTIVE
  The purpose of this study is to investigate the plasma adiponectin level and thoracic aortic calcification (TAC) in Chinese elderly.
  
  
  BACKGROUND
  The association of serum adiponectin levels and thoracic aortic calcification has not been reported.
  
  
  METHODS
  Total plasma adiponectin level was measured by ELISA. TAC was evaluated by posterior-anterior chest radiographs. Osteoporosis was diagnosed using dual energy X-ray absorptiometry.
  
  
  RESULTS
  The mean plasma adiponectin level was 6.3 ± 3.7 μg/ml, TAC was detected in 58% of subjects, and comorbidities of TAC and osteoporosis were observed in 33.6% subjects. The percentages of TAC or comorbidities of TAC and osteoporosis were higher in subjects with low adiponectin tertile level than that in patients with intermediate or high adiponectin tertile level. Multivariable logistic regression analysis showed that adiponectin level was negatively associated with TAC prevalence.
  
  
  CONCLUSIONS
  Plasma adiponectin level is associated with TAC and lower plasma adiponectin level may be a useful indicator of artery calcification in the elderly.
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Jun-Kun
authors.initials: JK
authors.lastname: Zhan
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Jie-Yu
authors.initials: JY
authors.lastname: He
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Yan-Jiao
authors.initials: YJ
authors.lastname: Wang
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Pan
authors.initials: P
authors.lastname: Tan
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Tang
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Hui-Qian
authors.initials: HQ
authors.lastname: Deng
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China.
authors.forename: Wu
authors.initials: W
authors.lastname: Huang
authors.affiliation: Geriatric Department of the Second Xiang-Ya Hospital, Institute of Aging and Geriatrics, Central South University, Changsha, Hunan 410011, PR China. Electronic address: liuyoushuo@yeah.net.
authors.forename: You-Shuo
authors.initials: YS
authors.lastname: Liu
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000368:Aged; D000369:Aged, 80 and over; D001013:Aorta, Thoracic; D001018:Aortic Diseases / Q000097:blood / Q000453:epidemiology*; D002114:Calcinosis / Q000097:blood / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000097:blood / Q000453:epidemiology*; D015995:Prevalence; D061205:Vascular Calcification / Q000097:blood / Q000453:epidemiology*
chemical_list: D052242:Adiponectin
keywords: Adiponectin; Artery calcification; Bone mineral density; Elderly; Osteoporosis