title: Exercise training at the crossover point improves bodily and cardiorespiratory data but not quality of life in women with metabolic syndrome.
abstract: BACKGROUND
  This study investigated the effects of an exercise program at the intensity corresponding to the crossover point of substrate utilization (COP) on anthropometric measures, health-related quality of life (HRQoL) and cardiorespiratory fitness (i.e., peak oxygen uptake [V̇O2peak] and peak power output [Ppeak]) in women with metabolic syndrome (MetS).
  
  
  METHODS
  Nineteen obese and post-menopausal women with MetS (age: 54.8±8.1 years, body mass: 89.0±12.2 kg, Body Mass Index: 34.5±4.0 kg/m2) followed a 12-week program consisting of three 45-minute sessions per week of cycle ergometer exercise. The imposed exercise intensity corresponded to COP. Before and after the program, HRQoL, V̇O2peak and Ppeak were measured and then compared.
  
  
  RESULTS
  Body mass (89.0±12.2 vs. 86.2±11.0 kg), Body Mass Index (34.5±4.0 vs. 33.4±3.6 kg/m2), waist (106±10 vs. 100±9 cm) and hip (117±11 vs. 114±11 cm) circumferences, waist-to-hip ratio (0.91±0.07 vs. 0.88±0.07), fat mass (43.3±4.6 vs. 41.9±4.6%), fat-free mass (56.7±4.6 vs. 58.2±4.6%), V̇O2peak (16.6±3.4 vs. 18.1±4.1 mL/min/kg) and Ppeak (102±22 vs. 125±27 W) were significantly improved after the exercise program (P<0.05), but HRQoL showed no significant improvement on any subscale (i.e., physical functioning: performance limitation for physical activities including bathing and dressing, role physical: problems with work or other daily activities, bodily pain, general health, vitality, social functioning, role emotional and mental health; P>0.05).
  
  
  CONCLUSIONS
  Although a 12-week exercise program at COP improved anthropometric measures and cardiorespiratory fitness in women with MetS, self-perceived HRQoL did not significantly improve. This finding may be linked to a significant but still insufficient reduction in body mass, probably because COP is too weak exercise intensity to induce important energy expenditure.
authors.affiliation: Université de Rouen, CETAPS, EA 3832, Mont Saint Aignan, France - jeremy.coquart@yahoo.com.
authors.forename: Jeremy B
authors.initials: JB
authors.lastname: Coquart
authors.affiliation: Université de Lille, Lille, France.|UDSL, EA4488, Ronchin, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Boitel
authors.affiliation: Université de Limoges, HAVAE, EA 6310, Limoges, France.
authors.forename: Benoit
authors.initials: B
authors.lastname: Borel
authors.affiliation: Université de Lille, Département des Bio-Statistiques, EA 2694, Lille, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Duhamel
authors.affiliation: Université de Lille, Lille, France.|Centre Hospitalier Universitaire de Lille, Service des Explorations Fonctionnelles et Respiratoires, Lille, France.
authors.forename: Regis
authors.initials: R
authors.lastname: Matran
authors.affiliation: Centre Hospitalier Universitaire de Lille, Service de Médecine Vasculaire et d'Hypertension Artérielle, Lille, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Delsart
authors.affiliation: Centre Hospitalier Universitaire de Lille, Service de Médecine Vasculaire et d'Hypertension Artérielle, Lille, France.
authors.forename: Claire
authors.initials: C
authors.lastname: Mounier-Vehier
authors.affiliation: Université de Lille, Lille, France.|UDSL, EA4488, Ronchin, France.
authors.forename: Murielle
authors.initials: M
authors.lastname: Garcin
mesh_terms: D000328:Adult; D005080:Exercise Test / Q000379:methods; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D024821:Metabolic Syndrome / Q000503:physiopathology / Q000628:therapy*; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology / Q000628:therapy*; D010809:Physical Fitness / Q000502:physiology*; D017698:Postmenopause; D011788:Quality of Life