title: Highly Selective Cascade C-C Bond Formation via Palladium- Catalyzed Oxidative Carbonylation-Carbocyclization-Carbonylation-Alkynylation of Enallenes.
abstract: A highly efficient palladium-catalyzed oxidative cascade reaction of enallenes undergoing overall four C-C bond formations has been developed. The insertion cascade proceeds via carbonylation-carbocyclization-carbonylation-alkynylation involving sequential insertion of carbon monoxide, olefin, and carbon monoxide. Furthermore, different types of terminal alkynes and functionalized enallenes have been investigated and found to undergo the cascade reaction under mild reaction conditions.
authors.affiliation: Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University , SE-106 91 Stockholm, Sweden.
authors.forename: Can
authors.initials: C
authors.lastname: Zhu
authors.affiliation: Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University , SE-106 91 Stockholm, Sweden.
authors.forename: Bin
authors.initials: B
authors.lastname: Yang
authors.affiliation: Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University , SE-106 91 Stockholm, Sweden.
authors.forename: Jan-E
authors.initials: JE
authors.lastname: Bäckvall