title: The Relationship Between Iron Deficiency and Febrile Convulsion: A Case-Control Study.
abstract: BACKGROUND
  Febrile seizure is among the most common convulsion disorders in children, which strikes 2% to 5% of children between 3 to 60 months of age. Some studies have reported that iron deficiency could be a risk factor for febrile seizure. The present study was conducted to compare the rate of iron deficiency anemia in febrile children with and without seizure.
  
  
  METHODS
  This case-control study evaluated 200 children aged 6-60 month in two 100 person groups (febrile seizure and febrile without convulsion) in Kashan. The CBC diff, serum iron and TIBC were done for all of participants. Diagnosis of iron deficiency anemia based on mentioned tests.
  
  
  RESULTS
  No significant differences were found in two groups regarding to the age, gender, and the disease causing the fever. The presence of iron deficiency anemia was 45% in the convulsion group and 22% in the group with fever without convulsion. The Chi Square test indicated a significant difference between two groups.
  
  
  CONCLUSIONS
  The findings suggest that a considerable percentage of children having febrile seizure suffer from iron-deficiency anemia and low serum iron. This means the low serum iron and presence of anemia can serve as a reinforcing factor for the febrile seizure in children.
authors.affiliation: Associate professor, Department of Pediatrics, Kashan University of Medical Sciences, Kashan, I.R. Iran.. hamedir2010@gmail.com.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Sharif
authors.forename: Davood
authors.initials: D
authors.lastname: Kheirkhah
authors.forename: Mahla
authors.initials: M
authors.lastname: Madani
authors.forename: Hamed Haddad
authors.initials: HH
authors.lastname: Kashani
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000150:complications / Q000175:diagnosis*; D001772:Blood Cell Count; D016022:Case-Control Studies; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012307:Risk Factors; D003294:Seizures, Febrile / Q000175:diagnosis* / Q000209:etiology