title: A high-throughput colorimetric assay for glucose detection based on glucose oxidase-catalyzed enlargement of gold nanoparticles.
abstract: We developed a simple high-throughput colorimetric assay to detect glucose based on the glucose oxidase (GOx)-catalysed enlargement of gold nanoparticles (AuNPs). Compared with the currently available glucose kit method, the AuNP-based assay provides higher clinical sensitivity at lower cost, indicating its great potential to be a powerful tool for clinical screening of glucose.
authors.affiliation: College of Chemistry, Research Center for Analytical Sciences, State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Molecular Recognition and Biosensing, and Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, 94 Weijin Road, Tianjin 300071, China. liudb@nankai.edu.cn.
authors.forename: Yanmei
authors.initials: Y
authors.lastname: Xiong
authors.forename: Yuyan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Pengfei
authors.initials: P
authors.lastname: Rong
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Dingbin
authors.initials: D
authors.lastname: Liu
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D003124:Colorimetry / Q000379:methods*; D005949:Glucose Oxidase / Q000737:chemistry / Q000378:metabolism*; D006046:Gold / Q000737:chemistry*; D057166:High-Throughput Screening Assays / Q000379:methods*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*
chemical_list: D001786:Blood Glucose; D006046:Gold; D005949:Glucose Oxidase