title: In vivo identification of pancreatic cystic neoplasms with needle-based confocal laser endomicroscopy.
abstract: Pancreatic cystic lesions (PCLs) are increasingly identified with the widespread use of imaging modalities. The precise diagnosis of PCLs remains a challenge despite the use of CT, MRI, and EUS-FNA. Confocal laser endomicroscopy (CLE) is a new endoscopic imaging modality that provides real-time, very high magnification images. A smaller CLE probe, which can be passed through a 19-gauge FNA needle, is now available. Needle-based CLE during EUS has recently been examined to evaluate PLCs, and the specific criteria of nCLE for the diagnosis of PLCs have been proposed.
authors.affiliation: H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, United States.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tsujino
authors.affiliation: H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, United States.
authors.forename: Jason
authors.initials: J
authors.lastname: Yan-Lin Huang
authors.affiliation: Department of Gastroenterology, The Graduated School of Medicine, The University of Tokyo, Japan.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Nakai
authors.affiliation: H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, United States.
authors.forename: Jason B
authors.initials: JB
authors.lastname: Samarasena
authors.affiliation: H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, United States.
authors.forename: John G
authors.initials: JG
authors.lastname: Lee
authors.affiliation: H.H. Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, United States. Electronic address: kchang@uci.edu.
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Chang
mesh_terms: D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods*; D006801:Humans; D018613:Microscopy, Confocal / Q000295:instrumentation; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000175:diagnosis*; D010181:Pancreatic Cyst / Q000175:diagnosis*; D010190:Pancreatic Neoplasms / Q000175:diagnosis*
keywords: Confocal laser endomicroscopy; Endoscopic ultrasonography; Fine-needle aspiration; Pancreatic cystic lesions