title: Synthesis and stability of cyclic α-hydrogen nitroxides.
abstract: Nitroxides (nitroxyl radicals) hold a unique place in science due to their stable radical nature. We have recently reported the first design concept providing a general solution to the problem of designing and preparing monocyclic α-hydrogen nitroxides. The initial studies were limited to aryl derivatives. We now report a wider study showing that alkyl substituents may be employed as well. In addition, we report several additional examples of aryl substituents and reveal some of the structural limitations with regard to nitroxide stability as a function of the α-carbon substituent.
authors.affiliation: Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Israel. amszpilman@gmail.com.
authors.forename: Hila
authors.initials: H
authors.lastname: Toledo
authors.affiliation: Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Israel. amszpilman@gmail.com.
authors.forename: Michal
authors.initials: M
authors.lastname: Amar
authors.affiliation: Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Israel. amszpilman@gmail.com.
authors.forename: Sukanta
authors.initials: S
authors.lastname: Bar
authors.affiliation: Department of Chemical Research Support, Weizmann Institute of Science, Israel.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Iron
authors.affiliation: Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Israel. amszpilman@gmail.com.
authors.forename: Natalia
authors.initials: N
authors.lastname: Fridman
authors.affiliation: Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Israel. amszpilman@gmail.com.
authors.forename: Boris
authors.initials: B
authors.lastname: Tumanskii
authors.affiliation: Department of Chemical Research Support, Weizmann Institute of Science, Israel.
authors.forename: Linda J W
authors.initials: LJ
authors.lastname: Shimon
authors.affiliation: Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Israel. amszpilman@gmail.com.
authors.forename: Mark
authors.initials: M
authors.lastname: Botoshansky
authors.affiliation: Schulich Faculty of Chemistry, Technion - Israel Institute of Technology, Israel. amszpilman@gmail.com.
authors.forename: Alex M
authors.initials: AM
authors.lastname: Szpilman