title: Long-term ambient air pollution exposure and risk of high blood pressure among citizens in Nis, Serbia.
abstract: Epidemiological studies suggest that long-term exposure to air pollution increases the risk for high blood pressure (BP). The aim of our study is to evaluate any effects in BP in citizens exposed to long-term ambient air pollution. The subjects are 1136 citizens, aged 18-70 years, living for more than 5 years in the same home in the areas with a different level of air pollution. The air concentrations of black smoke and sulfur dioxide were determined in the period from 2001 to 2011. We measured systolic and diastolic BP and heart rate. Multivariate methods were used in the analysis. Alcohol consumption had the greatest influence on the incidence of hypertension as a risk factor (RR: 3.461; 95% CI: 1.72-6.93) and age had the least (RR: 1.23; 95% CI: 1.183-1.92). Exposure to air pollution increases risk for developing hypertension 2.5 times (95% CI: 1.46-4.49). Physical activity has proved to be statistically significant protective factor for the development of hypertension. Long-term exposure to low levels of main air pollutants is significantly associated with elevated risk of hypertension.
authors.affiliation: a Medical Faculty, University of Nis , Nis , Serbia.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Stanković
authors.affiliation: a Medical Faculty, University of Nis , Nis , Serbia.
authors.forename: Maja
authors.initials: M
authors.lastname: Nikolić
mesh_terms: D000328:Adult; D000393:Air Pollutants / Q000009:adverse effects / Q000032:analysis; D000397:Air Pollution / Q000009:adverse effects / Q000032:analysis; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D015994:Incidence; D019570:Inhalation Exposure / Q000009:adverse effects / Q000032:analysis / Q000706:statistics & numerical data; D000069451:Long Term Adverse Effects / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D052638:Particulate Matter / Q000009:adverse effects / Q000032:analysis; D012307:Risk Factors; D055771:Serbia / Q000453:epidemiology; D012959:Socioeconomic Factors
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter
keywords: Air pollution; black smoke; blood pressure; heart rate; sulfur dioxide