title: Work-related respiratory symptoms in Champagne vineyard workers.
abstract: BACKGROUND
  Vineyard workers (VW) are exposed to various respiratory allergens. The aims of the study were to determine the prevalence of work related respiratory symptoms (WRS) in Champagne VW in France and to analyze the relationships between symptoms, occupational exposure and sensitization profile.
  
  
  METHODS
  VW of Reims area were prospectively recruited between 2007 and 2010. Demographic and occupational characteristics were recorded. Respiratory symptoms were scored for each month of the past year. Results of respiratory functional tests and skin prick tests for common respiratory allergens, grape moulds and vine pollen were recorded.
  
  
  RESULTS
  307 subjects were included. The prevalence of WRS was 11%. Compared to subjects with symptoms unrelated to work, subjects with WRS were more frequently sensitized to gramineae (34% vs 18%, p = 0.05), described ocular itching (74% vs 37%, p < 0.001) and seasonal symptoms (88% vs 69%, p = 0.03) mainly during lifting and trellising (57% vs 17%, p < 0.001).
  
  
  CONCLUSIONS
  WRS are frequent in Champagne WV and are associated with a sensitization to gramineae and with activities performed close to vine in late spring.
authors.affiliation: Department of Respiratory Medicine, University Hospital, 51100 Reims, France. INSERM UMRS 903, University Hospital, 51100, 45 Rue Cognacq Jay, 51100 Reims, France. Phone: +33 32 67 87 614 Fax: +33 32 678 40 30 E-mail: jmperotin-collard@chu-reims.fr.
authors.forename: J-M
authors.initials: JM
authors.lastname: Perotin
authors.affiliation: Clinical Research Unit, University Hospital, 51100 Reims, France.
authors.forename: C
authors.initials: C
authors.lastname: Barbe
authors.affiliation: Department of Respiratory Medicine, University Hospital, 51100 Reims, France.
authors.forename: K L
authors.initials: KL
authors.lastname: Nguyen
authors.affiliation: Department of Respiratory Medicine, University Hospital, 51100 Reims, France.
authors.forename: J-F
authors.initials: JF
authors.lastname: Fontaine
authors.affiliation: Department of Occupational Medicine, Mutualité Sociale Agricole, 51100 Reims, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Gabignon
authors.affiliation: Department of Respiratory Medicine, University Hospital, 51100 Reims, France.
authors.forename: J
authors.initials: J
authors.lastname: Nardi
authors.affiliation: Department of Respiratory Medicine, University Hospital, 51100 Reims, France.
authors.forename: C
authors.initials: C
authors.lastname: Launois
authors.affiliation: Department of Respiratory Medicine, University Hospital, 51100 Reims, France.
authors.forename: F
authors.initials: F
authors.lastname: Lebargy
authors.affiliation: Department of Respiratory Medicine, University Hospital, 51100 Reims, France.
authors.forename: F
authors.initials: F
authors.lastname: Lavaud
authors.affiliation: Department of Respiratory Medicine, University Hospital, 51100 Reims, France. INSERM UMRS 903, University Hospital, 51100 Reims, France.
authors.forename: G
authors.initials: G
authors.lastname: Deslee
mesh_terms: D000328:Adult; D000382:Agricultural Workers' Diseases / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006109:Poaceae / Q000276:immunology; D011446:Prospective Studies; D012140:Respiratory Tract Diseases / Q000209:etiology*; D006255:Rhinitis, Allergic, Seasonal / Q000209:etiology; D027843:Vitis
keywords: Rhinitis; respiratory symptoms; vineyard worker; work-related symptom