title: Sensitization Rates for Various Allergens in Children with Allergic Rhinitis in Qingdao, China.
abstract: The aim of this study was to determine the prevalence of sensitization to common allergens in children with allergic rhinitis (AR) living in Qingdao, China. We conducted a retrospective analysis for AR cases, who underwent skin prick tests (SPT) in Qingdao. A total of 2841 children with AR qualified for the inclusion criteria (Age 3-5 years: 1500 children; Age 6-12 years: 1341 children). The most common inhaled allergens to which the AR children were sensitive were Dermatophagoides pteronyssinus (69.3%), Dermatophagoides farinae (66.2%) and mould 1 (Penicillium notatum 38.9%); while the corresponding ingested allergens were mussel (39.2%), shrimp (36.3%) and carp (36.5%). The prevalence of sensitization to inhaled allergens and food allergens was higher in children >6 years of age as compared to that in children 3-5 years of age (all p < 0.05). Children >6 years old were more sensitive to dust mite as compared to children 3-5 years old (p < 0.05). Sensitization to dust mite was more common in males than in females (p = 0.05). In this study, Dermatophagoides pteronyssinus and Dermatophagoides farinae were the most common allergens causing AR in children in Qingdao, China. Older children with AR, particularly males, were found to be more sensitive to dust mite.
authors.affiliation: Department of Otorhinolaryngology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China. linhang0609@sina.com.
authors.forename: Hang
authors.initials: H
authors.lastname: Lin
authors.affiliation: Department of Pediatrics, The Affiliated Hospital of Qingdao University, Qingdao 266003, China. linrongjun0312@126.com.
authors.forename: Rongjun
authors.initials: R
authors.lastname: Lin
authors.affiliation: Department of Otorhinolaryngology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China. dr.lina@163.com.
authors.forename: Na
authors.initials: N
authors.lastname: Li
mesh_terms: D000485:Allergens / Q000276:immunology*; D000818:Animals; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D005658:Fungi; D006801:Humans; D008297:Male; D015995:Prevalence; D039981:Pyroglyphidae; D012189:Retrospective Studies; D065631:Rhinitis, Allergic / Q000175:diagnosis / Q000453:epidemiology*; D017747:Seafood; D012758:Shellfish; D012882:Skin Tests
chemical_list: D000485:Allergens
keywords: China; Qingdao; allergen; allergic rhinitis; children