title: Vicinal α,β-functionalizations of amines: cyclization versus dehydrogenative hydrolysis.
abstract: Direct vicinal α,β-difunctionalization of tertiary cyclic amines is achieved in the presence of ruthenium or iridium transition-metal complexes featuring phosphine-sulfonate chelates. By varying the reaction conditions, α-alkylated lactams were obtained by a formal dehydrogenative hydrolysis in which one molecule of hydrogen is generated from water.
authors.affiliation: UMR6226 CNRS, Institut des Sciences Chimiques de Rennes, Université de Rennes1, OMC: Organometallics: Materials and Catalysis, Campus de Beaulieu, 35042 Rennes Cedex (France).
authors.forename: Fan
authors.initials: F
authors.lastname: Jiang
authors.affiliation: UMR6226 CNRS, Institut des Sciences Chimiques de Rennes, Université de Rennes1, OMC: Organometallics: Materials and Catalysis, Campus de Beaulieu, 35042 Rennes Cedex (France). mathieu.achard@univ-rennes1.fr.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Achard
authors.affiliation: UMR6226 CNRS, Institut des Sciences Chimiques de Rennes, Université de Rennes1, OMC: Organometallics: Materials and Catalysis, Campus de Beaulieu, 35042 Rennes Cedex (France).
authors.forename: Christian
authors.initials: C
authors.lastname: Bruneau
keywords: alkylation; chelate; cyclization; dehydrogenative hydrolysis; hydrogen