title: Nematicidal triterpenoids from Lantana camara.
abstract: A new triterpene, lancamarolide (1), and seven known triterpenes, oleanonic acid (2), lantadene A (3), 11α-hydroxy-3-oxours-12-en-28-oic acid (4), betulinic acid (5), lantadene B (6), and lantaninilic acid (7) were isolated from the aerial parts of Lantana camara in the course of bioassay-guided isolation, and their nematicidal activities against Meloidogyne incognita, the root knot nematode, were carried out. Oleanonic acid was found to be the most active compound and exhibited 80% mortality after 72 h at 0.0625% concentration, which is comparable with that of the standard furadan.
authors.affiliation: H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan, (phone: +92-21-99261701-2; fax: +92-21-99261713). dr.sabirabegum@yahoo.com.
authors.forename: Sabira
authors.initials: S
authors.lastname: Begum
authors.affiliation: H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan, (phone: +92-21-99261701-2; fax: +92-21-99261713).
authors.forename: Anjum
authors.initials: A
authors.lastname: Ayub
authors.affiliation: H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan, (phone: +92-21-99261701-2; fax: +92-21-99261713).
authors.forename: Bina
authors.initials: B
authors.lastname: Shaheen Siddiqui
authors.affiliation: National Nematological Research Center, University of Karachi, Karachi 75270, Pakistan.
authors.forename: Shahina
authors.initials: S
authors.lastname: Fayyaz
authors.affiliation: National Nematological Research Center, University of Karachi, Karachi 75270, Pakistan.
authors.forename: Firoza
authors.initials: F
authors.lastname: Kazi
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D032410:Lantana / Q000737:chemistry*; D010944:Plants / Q000469:parasitology*; D017190:Secernentea Infections / Q000188:drug therapy; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D014431:Tylenchoidea / Q000187:drug effects*
chemical_list: D000969:Antinematodal Agents; D014315:Triterpenes; C450739:oleanonic acid
keywords: Lancamarolide; Lantana camara; Meloidogyne incognita; Nematicidal activity; Root-knot nematodes; Triterpenoids