title: Noncontact full-angle fluorescence molecular tomography system based on rotary mirrors.
abstract: We propose a novel noncontact fluorescence molecular tomography system that achieves full-angle capacity with the use of a new rotary-mirrors-based imaging head. In the imaging head, four plane mirrors are mounted on a rotating gantry to enable illumination and detection over 360°. In comparison with existing full-angle systems, our system does not require rotation of the specimen animal, a large and heavy light source (with scanning head), or a bulky camera (with filters and lens). The system design and implementation are described in detail. Both physical phantom and in vivo experiments are performed to verify the performance of the proposed system.
authors.forename: Daifa
authors.initials: D
authors.lastname: Wang
authors.forename: Jin
authors.initials: J
authors.lastname: He
authors.forename: Huiting
authors.initials: H
authors.lastname: Qiao
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.forename: Yubo
authors.initials: Y
authors.lastname: Fan
authors.forename: Deyu
authors.initials: D
authors.lastname: Li
mesh_terms: D000465:Algorithms; D000818:Animals; D004867:Equipment Design; D005453:Fluorescence; D005898:Glass; D007091:Image Processing, Computer-Assisted; D007834:Lasers; D008027:Light; D008029:Lighting / Q000379:methods; D051379:Mice; D008819:Mice, Nude; D008856:Microscopy, Fluorescence / Q000379:methods*; D057054:Molecular Imaging / Q000379:methods; D055095:Optics and Photonics; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D014054:Tomography / Q000379:methods*