title: Non-contiguous meningeal metastases of olfactory neuroblastoma.
abstract: Olfactory neuroblastoma (ONB) is a malignant neoplasm centered along the roof of the nasal cavity near the cribriform plate. Although metastasis of this tumor has been reported, non-contiguous spread to the dura is rare. Here, we report the largest series of intracranial meningeal metastases of ONBs from M.D. Anderson Cancer Center and the University of Toronto. The unique natural history and geographical distribution of these metastatic lesions suggest a common mechanism of tumor spread along the dural vascular arborization.
authors.affiliation: Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA.
authors.forename: Wen
authors.initials: W
authors.lastname: Jiang
authors.affiliation: Department of Breast Surgery, Sun Yat-sen Memorial Hospital, Breast Tumor Center, Sun Yat-sen University, Guangzhou, China.
authors.forename: Jieqiong
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Head and Neck Surgery, University of Toronto, 399 Bathurst Street, Toronto, ON, M5T 2S8, USA.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Gullane
authors.affiliation: Department of Neurosurgery, University of Toronto, 399 Bathurst Street, Toronto, ON, M5T 2S8, USA.
authors.forename: Fred
authors.initials: F
authors.lastname: Gentili
authors.affiliation: Department of Neurosurgery, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
authors.forename: Robert E
authors.initials: RE
authors.lastname: Wharen
authors.affiliation: Department of Neurosurgery, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. kim.betty@mayo.edu.
authors.forename: Betty Y S
authors.initials: BYS
authors.lastname: Kim
authors.affiliation: Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX, 77030, USA. fdemonte@mdanderson.org.
authors.forename: Franco
authors.initials: F
authors.lastname: DeMonte
mesh_terms: D018304:Esthesioneuroblastoma, Olfactory / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000556:secondary*; D009296:Nasal Cavity / Q000473:pathology* / Q000601:surgery; D019635:Neurosurgical Procedures / Q000379:methods; D009669:Nose Neoplasms / Q000473:pathology*
keywords: Esthesioneuroblastoma; Intracranial; Leptomeningeal metastasis; Olfactory Neuroblastoma