title: [Neurological complications of posterior vertebral column resection for severe rigid congenital spinal deformities].
abstract: OBJECTIVE
  To analyze the risk factors of neurological complications of posterior vertebral column resection in the treatment of severe rigid congenital spinal deformities.
  
  
  METHODS
  The clinical data of 88 patients with severe rigid congenital spinal deformities who underwent PVCR in Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University from June 2007 to November 2012 were collected. There were 39 males and 49 females at the average age of 16.9 years (range 6-46 years). To measure the Cobb angle and balance at preoperative, postoperative and follow up, and to record the operation report, neurological complications and at follow up. The relevant factors of neurological complications were analyzed by one-way analysis, including: age, Cobb angle, operation time, body mass index, pulmonary function, blood volume loss, resection level, number of vertebrae fixed, number of vertebrae resected, usage of cage or titanium mesh, preoperative neurologic function, the type of deformity and combination of spinal canal deformity, and further analyzed by multiariable Logistic regression analysis.
  
  
  RESULTS
  The average follow up was 42 months (range 19 to 83 months). The number of resected vertebrae average 1.3 (range 1 to 3), operative time average 502.4 min (range 165.0 to 880.0 min), estimate blood loss average 2,238 ml (range 100 to 11,500 ml) for an average 69.3% blood volume loss (range 9% to 299%). The average preoperative major coronal curve of 93.6° corrected to 22.2°, at the final follow-up, the coronal curve was 22.2° with a correction of 76.8%. The average preoperative coronal imbalance (absolute value) was 2.5 cm decreasing to 1.3 cm at the final follow-up. The average preoperative major sagittal curve of 88.2° corrected to 28.7°, at the final follow-up, the sagittal curve was 29.2°, average decrease in kyphosis of 59.0°. The average preoperative sagittal imbalance (absolute value) was 3.1 cm decreasing to 1.2 cm at the final follow-up. There were 12 patients (13.6%) developed a neurological complications. High rate of neurological complications was occurred in patients with operative time greater than 480 min, pulmonary dysfunction, blood volume loss greater than 50%, T7-T99 osteotomy and preoperative neurologic compromise (P=0.046, 0.000, 0.000, 0.033, 0.043).
  
  
  CONCLUSIONS
  Posterior vertebral column resection can achieve satisfactory efficacy in treatment of severe spinal deformities. Pulmonary dysfunction and blood volume loss greater than 50% were significant risk factors of neurological complications.
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China; Email: taohr816@fmmu.edu.cn.
authors.forename: Huiren
authors.initials: H
authors.lastname: Tao
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Jinghui
authors.initials: J
authors.lastname: Huang
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Shen
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Xiangbo
authors.initials: X
authors.lastname: Chen
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Weizhou
authors.initials: W
authors.lastname: Yang
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department Of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Zhuojing
authors.initials: Z
authors.lastname: Luo
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007738:Kyphosis; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D019637:Orthopedic Procedures; D010027:Osteotomy; D012189:Retrospective Studies; D012307:Risk Factors; D012600:Scoliosis; D013115:Spinal Canal; D013122:Spinal Diseases / Q000601:surgery*; D013131:Spine / Q000002:abnormalities* / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult