title: Gastric Microbiota.
abstract: After the discovery of Helicobacter pylori in 1983, the stomach was no longer considered a sterile environment. In 2015, evolving data shows that H. pylori is not the only inhabitant of the gastric mucosa. Using culture-independent methods of analysis, a non-H. pylori microbial community has been recently observed in the human stomach, the so-called human gastric microbiota, along with H. pylori itself. Increasing evidence supports the hypothesis that although H. pylori may be the most relevant, it is not the only local bacterial culprit leading to gastric diseases. Further studies are warranted to offer a better picture of the role and functions of gastric microbiota and to identify the best therapeutic modulators of gut microbiota for the management of gastric diseases.
authors.affiliation: Division of Internal Medicine, Gastroenterology and Liver Disease, Department of Internal Medicine, "A. Gemelli" University Hospital, Rome, Italy.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Ianiro
authors.affiliation: Department of Gastroenterology, Hospital San Pedro de Alcantara, Caceres, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Molina-Infante
authors.affiliation: Division of Internal Medicine, Gastroenterology and Liver Disease, Department of Internal Medicine, "A. Gemelli" University Hospital, Rome, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Gasbarrini
mesh_terms: D000818:Animals; D001419:Bacteria / Q000145:classification* / Q000302:isolation & purification*; D005753:Gastric Mucosa / Q000382:microbiology*; D006801:Humans; D064307:Microbiota
keywords: H. pylori; gastric cancer; gastric diseases; gut microbiota; probiotics