title: Preparation and Properties of Nano-Hydroxyapatite/Gelatin/Poly(vinyl alcohol) Composite Membrane.
abstract: In this study, the bone-like composite membrane based on blends of gelatin (Gel), nano-hydroxyapatite (n-HA) and poly(vinyl alcohol) (PVA) was fabricated by solvent casting and evaporation methods. The effect of n-HA content and the ratio of Gel/PVA on the properties of the composite was investigated. The Gel/PVA and n-HA/Gel/PVA composite membranes were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), water contact angle measurement and scanning electron microscopy (SEM). The mechanical properties of the composites were determined by tensile tests. The as prepared composite membranes exhibited hydrophobility, the water contact angle of composite membrane was 126.6 when its mass ratio of n-HA/Gel/PVA was 10/50/40. The tensile strength of composite membranes was greatly increased due to the introduction of n-HA, and the tensile strength was increased to 74.92 MPa when the mass ratio of n-HA/Gel/PVA was 10/50/40. SEM observation indicated that n-HA was dispersed in the membranes and a sea-island structure was formed in the n-HA/Gel/PVA composite membranes, resulting in a significant increase in tensile strength. The as-prepared n-HA/Gel/PVA composite membranes may be applied in the field of bone tissue engineering.
authors.forename: Haotian
authors.initials: H
authors.lastname: Liao
authors.forename: Kun
authors.initials: K
authors.lastname: Shi
authors.forename: Jinrong
authors.initials: J
authors.lastname: Peng
authors.forename: Ying
authors.initials: Y
authors.lastname: Qu
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Liao
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Qian
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D005780:Gelatin / Q000737:chemistry*; D008422:Materials Testing; D008567:Membranes, Artificial; D053761:Nanocomposites / Q000737:chemistry*; D011143:Polyvinyl Chloride / Q000737:chemistry*; D013718:Tensile Strength; D023822:Tissue Engineering
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D005780:Gelatin; D011143:Polyvinyl Chloride; D017886:Durapatite