title: Tracheal Atresia with Segmental Esophageal Duplication: An Unusual Anatomic Arrangement.
abstract: An unusual anatomic configuration of segmental tracheal agenesis/atresia with esophageal duplication on autopsy in a fetus that demised in utero at 29 weeks is reported. The mother was scanned initially for a cardiac anomaly at 20 weeks and on follow-up scan at 27 weeks had polyhydramnios and underwent amnioreduction. The final autopsy diagnosis was vertebral, ano-rectal, cardiac, tracheoesophageal, renal, and limb malformations (VACTERL). We discuss the autopsy findings along with the embryological mechanisms and compare the configuration with Floyd's classification for tracheal agenesis. The difficulties in prenatal diagnosis are discussed.
authors.affiliation: 1 Mater Centre for Maternal Fetal Medicine, Mater Health Services, S. Brisbane QLD Australia; and the Mater Research Institute/University of Queensland, Brisbane QLD Australia.
authors.forename: Kirsten
authors.initials: K
authors.lastname: Gaerty
authors.affiliation: 1 Mater Centre for Maternal Fetal Medicine, Mater Health Services, S. Brisbane QLD Australia; and the Mater Research Institute/University of Queensland, Brisbane QLD Australia.
authors.forename: Joseph T
authors.initials: JT
authors.lastname: Thomas
authors.affiliation: 1 Mater Centre for Maternal Fetal Medicine, Mater Health Services, S. Brisbane QLD Australia; and the Mater Research Institute/University of Queensland, Brisbane QLD Australia.
authors.forename: Scott
authors.initials: S
authors.lastname: Petersen
authors.affiliation: 2 Anatomical Pathology, Mater Health Services, S. Brisbane QLD Australia.|3 Mater Research Institute, University of Queensland, Brisbane QLD Australia.
authors.forename: Edwin
authors.initials: E
authors.lastname: Tan
authors.affiliation: 1 Mater Centre for Maternal Fetal Medicine, Mater Health Services, S. Brisbane QLD Australia; and the Mater Research Institute/University of Queensland, Brisbane QLD Australia.
authors.forename: Sailesh
authors.initials: S
authors.lastname: Kumar
authors.affiliation: 1 Mater Centre for Maternal Fetal Medicine, Mater Health Services, S. Brisbane QLD Australia; and the Mater Research Institute/University of Queensland, Brisbane QLD Australia.
authors.forename: Glenn
authors.initials: G
authors.lastname: Gardener
authors.affiliation: 2 Anatomical Pathology, Mater Health Services, S. Brisbane QLD Australia.|3 Mater Research Institute, University of Queensland, Brisbane QLD Australia.
authors.forename: Jane
authors.initials: J
authors.lastname: Armes
mesh_terms: D000015:Abnormalities, Multiple; D000328:Adult; D001003:Anal Canal / Q000002:abnormalities* / Q000196:embryology; D001344:Autopsy; D001706:Biopsy; D003251:Constriction, Pathologic / Q000175:diagnosis* / Q000196:embryology / Q000235:genetics; D004947:Esophagus / Q000002:abnormalities* / Q000196:embryology; D005260:Female; D005313:Fetal Death; D020022:Genetic Predisposition to Disease; D005865:Gestational Age; D006330:Heart Defects, Congenital / Q000175:diagnosis* / Q000196:embryology / Q000235:genetics; D006801:Humans; D007668:Kidney / Q000002:abnormalities* / Q000196:embryology; D017880:Limb Deformities, Congenital / Q000175:diagnosis* / Q000196:embryology / Q000235:genetics; D010641:Phenotype; D011237:Predictive Value of Tests; D013131:Spine / Q000002:abnormalities* / Q000196:embryology; D014132:Trachea / Q000002:abnormalities* / Q000196:embryology; D016216:Ultrasonography, Prenatal
keywords: esophageal duplication, segmental anomalies, tracheal atresia