title: [Vacuum-therapy of postoperative sternomediastinitis].
abstract: OBJECTIVE
  To estimate the results of sternomediastinitis management using vacuum-therapy compared with conventional treatment of such wounds.
  
  
  METHODS
  We have retrospectively analyzed data for the period from January 2007 to October 2014. The study enrolled 79 patients with infectious complication after cardiac surgery. All patients underwent coronary artery bypass grafting. The first group included 40 patients who received conventional therapy. The second group enrolled 39 patients in whom vacuum-therapy was applied. Patients were comparable in main characteristics.
  
  
  RESULTS
  Mortality rate was significantly lower in vacuum-therapy group (2.5% vs. 15%, p=0.05). Similarly duration of hospital-stay in the 2nd group was 29±10 days, in the 1st group - 47±11 days (p<0.01). Incidence of sepsis and other complications was significantly higher in group of conventional treatment.
  
  
  CONCLUSIONS
  Vacuum-therapy for infectious complications after cardiac surgery provided good results including decrease of hospital-stay duration and mortality rate in comparison with conventional management of wounds.
authors.affiliation: Acad. E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Russian Health Ministry.
authors.forename: T M
authors.initials: TM
authors.lastname: Ruzmatov
authors.affiliation: Acad. E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Russian Health Ministry.
authors.forename: V U
authors.initials: VU
authors.lastname: Éfendiev
authors.affiliation: Acad. E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Russian Health Ministry.
authors.forename: A V
authors.initials: AV
authors.lastname: Boboshko
authors.affiliation: Acad. E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Russian Health Ministry.
authors.forename: E S
authors.initials: ES
authors.lastname: Malakhov
authors.affiliation: Acad. E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Russian Health Ministry.
authors.forename: A S
authors.initials: AS
authors.lastname: Nesmachnyĭ
authors.affiliation: Acad. E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Russian Health Ministry.
authors.forename: R A
authors.initials: RA
authors.lastname: Razumakhin
authors.affiliation: Acad. E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Russian Health Ministry.
authors.forename: Iu E
authors.initials: IE
authors.lastname: Kareva
authors.affiliation: Acad. E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Russian Health Ministry.
authors.forename: A M
authors.initials: AM
authors.lastname: Cherniavskiĭ
mesh_terms: D001026:Coronary Artery Bypass / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality / Q000639:trends; D006801:Humans; D015994:Incidence; D008297:Male; D008480:Mediastinitis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D010000:Osteitis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D012189:Retrospective Studies; D012800:Siberia / Q000453:epidemiology; D013249:Sternum; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome