title: A rare presentation of hydropneumothorax in tropical pulmonary eosinophilia: cavitation and pneumonic consolidation in a child.
abstract: Tropical pulmonary eosinophilia (TPE) is a syndrome of wheezing, fever and eosinophilia seen predominantly in the Indian subcontinent and other tropical areas. The pathogenesis is due to an exaggerated immune response to the filarial antigens which includes type I, type III and type IV reactions with eosinophils playing a pivotal role. Leucocytosis with an absolute increase in eosinophils in the peripheral blood is the hallmark of TPE. Other criteria for the diagnosis of TPE include high titres of antifilarial antibodies, raised serum total IgE > 1000 ku/L and a favourable response to the antifilarial agent, diethyl-carbamazine. Although TPE runs a benign course, if left untreated, it could result in a fair degree of respiratory morbidity.
authors.affiliation: Department Of Paediatrics, St Stephens Hospital, Tis Hazari, New Delhi, India varshneysaurabh2@gmail.com.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Department Of Paediatrics, St Stephens Hospital, Tis Hazari, New Delhi, India.
authors.forename: Rajbeer Singh
authors.initials: RS
authors.lastname: Beri
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004049:Diethylcarbamazine / Q000627:therapeutic use; D005368:Filariasis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D006801:Humans; D006872:Hydropneumothorax / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D008842:Microfilariae / Q000302:isolation & purification; D011657:Pulmonary Eosinophilia / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D014329:Tropical Climate
chemical_list: D000871:Anthelmintics; D004049:Diethylcarbamazine
keywords: DEC; Tropical pulmonary eosinophilia; wheezing