title: Tumefactive demyelinating lesions: Characteristics of individual lesions, individual patients, or a unique disease entity?
abstract: Whether or not recurrent tumefactive demyelinating lesions are a unique form of CNS demyelinating disease or part of the continuum of multiple sclerosis is a question raised by the case report on which this commentary is based. Detailed review and immunopathologic study of biopsy material may not only confirm or refute a diagnosis of demyelinating disease, but potentially uncover unique features that may assist in understanding pathophysiology and nosology of rare cases with recurrent tumefactive demyelination.
authors.affiliation: Department of Neurology, Mayo Clinic, USA weinb@mayo.edu.
authors.forename: Brian G
authors.initials: BG
authors.lastname: Weinshenker
mesh_terms: D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D003711:Demyelinating Diseases / Q000473:pathology*; D004660:Encephalitis / Q000473:pathology*; D005260:Female; D006423:Hemianopsia / Q000473:pathology*; D006801:Humans
keywords: Tumefactive; brain biopsy; demyelinating disease; multiple sclerosis