title: Multiple Subungual Pyogenic Granulomas Following Levothyroxine Treatment.
abstract: Pyogenic granulomas are benign vascular lesions that can result from a large number of etiological factors. Drugs are one etiological factor involved in pyogenic granuloma development. In this study we present our experience of multiple pyogenic granulomas following levothyroxine administration suggesting that levothyroxine hormone replacement therapy might play an important role in the formation of pyogenic granuloma. We also reviewed the literatures regarding drug-induced pyogenic granulomas.
authors.affiliation: *Department of Plastic Surgery, Numune Hospital, Konya, Turkey †Department of Plastic Surgery, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey ‡Department of Plastic Surgery, Buleun Health Care Center, Incheon, Republic of Korea §Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Musa Kemal
authors.initials: MK
authors.lastname: Keles
authors.forename: Engin
authors.initials: E
authors.lastname: Yosma
authors.forename: Ilhami Oguzhan
authors.initials: IO
authors.lastname: Aydogdu
authors.forename: Tekin
authors.initials: T
authors.lastname: Simsek
authors.forename: Tae Hwan
authors.initials: TH
authors.lastname: Park
mesh_terms: D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D017789:Granuloma, Pyogenic / Q000139:chemically induced*; D020249:Hormone Replacement Therapy / Q000009:adverse effects; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy; D008875:Middle Aged; D009260:Nail Diseases / Q000139:chemically induced*; D012008:Recurrence; D013974:Thyroxine / Q000009:adverse effects*; D000069470:Venlafaxine Hydrochloride / Q000627:therapeutic use
chemical_list: D018687:Antidepressive Agents, Second-Generation; D000069470:Venlafaxine Hydrochloride; D013974:Thyroxine