title: IL-17A Has Some Nerve!
abstract: Sensory neurons are important in controlling cutaneous inflammation, but the role of neurons in host antimicrobial defense was relatively unknown. Kaplan and colleagues now demonstrate that nociceptive fibers within the dermis play a crucial role in antifungal defenses through their influence on dermal dendritic cells and induction of IL-17A.
authors.affiliation: Department of Dermatology, University of California San Diego, La Jolla, CA 92093, USA.
authors.forename: James A
authors.initials: JA
authors.lastname: Sanford
authors.affiliation: Department of Dermatology, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: rgallo@ucsd.edu.
authors.forename: Richard L
authors.initials: RL
authors.lastname: Gallo
mesh_terms: D000818:Animals; D003713:Dendritic Cells / Q000276:immunology*; D007109:Immunity / Q000276:immunology*; D053759:Interleukin-23 / Q000276:immunology*; D011984:Sensory Receptor Cells / Q000276:immunology*; D012867:Skin / Q000276:immunology*
chemical_list: D053759:Interleukin-23