title: Knockdown of either filaggrin or loricrin increases the productions of interleukin (IL)-1α, IL-8, IL-18 and granulocyte macrophage colony-stimulating factor in stratified human keratinocytes.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Oita, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Sakai
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Oita, Japan. Electronic address: hatano@oita-u.ac.jp.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Hatano
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Oita, Japan.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Dermatology, Faculty of Medicine, Oita University, Oita, Japan.
authors.forename: Sakuhei
authors.initials: S
authors.lastname: Fujiwara
authors.affiliation: Medical student, Faculty of Medicine, Oita University, Oita, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Nishiyori
mesh_terms: D002478:Cells, Cultured; D015536:Down-Regulation; D000091344:Filaggrin Proteins; D055785:Gene Knockdown Techniques; D016179:Granulocyte Colony-Stimulating Factor / Q000378:metabolism*; D006801:Humans; D020382:Interleukin-18 / Q000378:metabolism*; D053582:Interleukin-1alpha / Q000378:metabolism*; D016209:Interleukin-8 / Q000378:metabolism*; D007381:Intermediate Filament Proteins / Q000235:genetics / Q000378:metabolism*; D015603:Keratinocytes / Q000276:immunology / Q000378:metabolism*; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D034622:RNA Interference; D014162:Transfection; D015854:Up-Regulation
chemical_list: C508606:CXCL8 protein, human; C000717249:FLG protein, human; D000091344:Filaggrin Proteins; C508584:IL1A protein, human; D020382:Interleukin-18; D053582:Interleukin-1alpha; D016209:Interleukin-8; D007381:Intermediate Filament Proteins; D008565:Membrane Proteins; C064554:loricrin; D016179:Granulocyte Colony-Stimulating Factor