title: The potential effect of Wuqinxi exercise for primary osteoporosis: A systematic review and meta-analysis.
abstract: This review aims to assess the effect of Wuqinxi exercise for primary osteoporosis. Literature search was conducted on the seven databases until June 2015. No statistical differences were found between the Wuqinxi versus no intervention, Wuqinxi plus antiosteoporosis medications versus antiosteoporosis medications on lumbar spine bone mineral density (BMD). However, Wuqinxi significantly improved lumbar spine BMD compared with antiosteoporosis medications (MD= 0.02g/cm(2); 95% CI: 0.01-0.03; P<0.0001). Wuqinxi plus antiosteoporosis medications had a better effect on femora BMD (MD=0.24g/cm(2); 95% CI: 0.18-0.30; P<0.00001). Additionally, the results showed a remarkable effect in improving pain score when Wuqinxi (MD=0.7; 95% CI: 0.31-1.09; P=0.0004) or Wuqinxi plus antiosteoporosis medications (MD=1.06; 95% CI: 0.57-1.55; P<0.0001) was used. An improvement was also identified in Wuqinxi plus antiosteoporosis medications on bone gla protein. Overall, Wuqinxi monotherapy or combination therapy can improve pain symptom, but the effect on BMD owing to poor study design and execution, inconsistency and imprecision is uncertain. It is recommended to exercise at least for 6 months, 5 times a week for around 30-60 min each time.
authors.affiliation: Department of Scientific Research, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Institute of Orthopaedics of Beijing Integrative Medicine, Beijing, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Wei
authors.affiliation: Department of Internal Medicine, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
authors.forename: Aili
authors.initials: A
authors.lastname: Xu
authors.affiliation: Department of Biology, Indiana University Purdue University Indianapolis, Indianapolis, USA.
authors.forename: Yukun
authors.initials: Y
authors.lastname: Yin
authors.affiliation: Department of Clinical Laboratory, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: bjzrx@sina.com.
authors.forename: Ranxing
authors.initials: R
authors.lastname: Zhang
mesh_terms: D015519:Bone Density; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D026241:Exercise Movement Techniques; D005081:Exercise Therapy / Q000379:methods*; D006801:Humans; D008159:Lumbar Vertebrae; D059352:Musculoskeletal Pain / Q000628:therapy; D010024:Osteoporosis / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic
chemical_list: D050071:Bone Density Conservation Agents
keywords: Primary osteoporosis; Randomized controlled trial; Systematic review; Wuqinxi exercise