title: Recent progress in revealing the biological and medical significance of the non-neuronal cholinergic system.
abstract: This special issue of International Immunopharmacology is the proceedings of the Fourth International Symposium on Non-neuronal Acetylcholine that was held on August 28-30, 2014 at the Justus Liebig University of Giessen in Germany. It contains original contributions of meeting participants covering the significant progress in understanding of the biological and medical significance of the non-neuronal cholinergic system extending from exciting insights into molecular mechanisms regulating this system via miRNAs over the discovery of novel cholinergic cellular signaling circuitries to clinical implications in cancer, wound healing, immunity and inflammation, cardiovascular, respiratory and other diseases.
authors.affiliation: Department of Dermatology, University of California, Irvine, CA 92697, USA.
authors.forename: Sergei A
authors.initials: SA
authors.lastname: Grando
authors.affiliation: Department of Molecular Pharmacology, Kitasato University School of Pharmacy, Tokyo 108-8641, Japan.
authors.forename: Koichiro
authors.initials: K
authors.lastname: Kawashima
authors.affiliation: Institute of Pathology, University Medical Center, Johannes Gutenberg-University, Mainz D-55101, Germany.
authors.forename: Charles J
authors.initials: CJ
authors.lastname: Kirkpatrick
authors.affiliation: Institute for Anatomy and Cell Biology, Justus-Liebig-University, Giessen D-35385, Germany.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Kummer
authors.affiliation: Institute of Pathology, University Medical Center, Johannes Gutenberg-University, Mainz D-55101, Germany.
authors.forename: Ignaz
authors.initials: I
authors.lastname: Wessler
mesh_terms: D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D002318:Cardiovascular Diseases / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology; D007249:Inflammation / Q000378:metabolism; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism*; D012140:Respiratory Tract Diseases / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D013234:Stem Cells / Q000502:physiology*; D014945:Wound Healing / Q000502:physiology
chemical_list: D035683:MicroRNAs; D000109:Acetylcholine
keywords: Acetylcholine