title: TUR-PSO: A cross-sectional, study investigating quality of life and treatment status of psoriasis patients in Turkey.
abstract: Psoriasis is a common inflammatory disease that has a severe impact on quality of life. There is lack of data regarding epidemiological and clinical features of psoriasis patients in Turkey, a country with a population of 76 million. The aim of this study was to define the demographic and clinical characteristics, quality of life and treatment patterns of psoriasis patients in Turkey. A cross-sectional observational study was conducted at 40 centers, chosen from geographically diverse locations in Turkey. Patients diagnosed with psoriasis were assessed by investigators who were specialists of dermatology using standardized study questionnaire forms. Dermatology Life Quality Index (DLQI) and EuroQol-5 dimension (EQ-5D) forms were also filled out by each patient. 3971 psoriasis patients were included in this study. 24.2% of plaque psoriasis patients had moderate to severe psoriasis (Psoriasis Area and Severity Index, ≥10). Mean DLQI was 7.03 ± 6.02; quality of life was moderately, severely or very severely affected in 49.2% of patients. The most severely affected component of EQ-5D was anxiety/depression. Among all patients, 22.9% were not receiving any treatment, 39.8% were receiving only topical treatment, 11.5% were on phototherapy, 26.1%, were taking conventional systemic agents and 4.1% were on a biologic treatment. 31.3% of psoriasis patients with moderate to severe disease were treated with only topical agents and only 30.5% of moderate to severe psoriasis patients were receiving systemic therapy. Moderate to severe psoriasis has a considerable impact on quality of life. Treatment in Turkey of patients with moderate to severe psoriasis is insufficient.
authors.affiliation: Department of Dermatology, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: Nilgün
authors.initials: N
authors.lastname: Atakan
authors.affiliation: Department of Dermatology, Mersin University School of Medicine, Mersin, Turkey.
authors.forename: Ayça Cordan
authors.initials: AC
authors.lastname: Yazici
authors.affiliation: Department of Dermatology, Istanbul University Istanbul School of Medicine, Istanbul, Turkey.
authors.forename: Güzin
authors.initials: G
authors.lastname: Özarmağan
authors.affiliation: Department of Dermatology, Gaziantep University School of Medicine, Gaziantep, Turkey.
authors.forename: Hüseyin Serhat
authors.initials: HS
authors.lastname: İnalÖz
authors.affiliation: Department of Dermatology, Gazi University School of Medicine, Ankara, Turkey.
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Gürer
authors.affiliation: Department of Dermatology, Osmangazi University School of Medicine, Eskisehir, Turkey.
authors.forename: İlham
authors.initials: İ
authors.lastname: Sabuncu
authors.affiliation: Dermatology Clinic, Istanbul Education and Research Hospital, Istanbul, Turkey.
authors.forename: Ümmühan
authors.initials: Ü
authors.lastname: Kİremİtçİ
authors.affiliation: Department of Dermatology, Ege University School of Medicine, Izmir, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Alper
authors.affiliation: Department of Dermatology, Dicle University School of Medicine, Diyarbakir, Turkey.
authors.forename: Sema
authors.initials: S
authors.lastname: Aytekİn
authors.affiliation: Department of Dermatology, Trakya University School of Medicine, Edirne, Turkey.
authors.forename: Özer
authors.initials: Ö
authors.lastname: Arican
authors.affiliation: Department of Dermatology, Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Mualla
authors.initials: M
authors.lastname: Polat
authors.affiliation: Department of Dermatology, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Doğan
authors.affiliation: Medical Department, Pfizer Turkey, Istanbul, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Aldİnç
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000209:etiology; D001688:Biological Products / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D003879:Dermatologic Agents / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010789:Phototherapy; D011565:Psoriasis / Q000473:pathology / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D014421:Turkey; D055815:Young Adult
chemical_list: D001688:Biological Products; D003879:Dermatologic Agents
keywords: cross-sectional; psoriasis; quality of life; severity; treatment