title: In Reply.
authors.affiliation: Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada (K.K.). keyvan.karkouti@uhn.ca.
authors.forename: Keyvan
authors.initials: K
authors.lastname: Karkouti
authors.forename: Jeannie
authors.initials: J
authors.lastname: Callum
authors.forename: Vivek
authors.initials: V
authors.lastname: Rao
authors.forename: Stuart A
authors.initials: SA
authors.lastname: McCluskey
mesh_terms: D000465:Algorithms; D001777:Blood Coagulation; D001803:Blood Transfusion / Q000592:standards*; D006348:Cardiac Surgical Procedures / Q000592:standards*; D006801:Humans; D065186:Interrupted Time Series Analysis / Q000592:standards*; D019095:Point-of-Care Systems / Q000592:standards*