title: Amiodarone-Induced Life-Threatening Refractory Hypotension.
abstract: BACKGROUND
  Amiodarone is frequently used in emergency departments for treatment of arrhythmias. Incidence of several amiodarone-related adverse events is unknown. The literature is sparse for potentially life-threatening adverse effects of amiodarone.
  
  
  METHODS
  We present a case of a male patient who presented with chest discomfort and rapid atrial fibrillation. He was known to have paroxysmal atrial fibrillation, which did not respond to initial beta-blocker treatment. The second-line drug amiodarone was given to the patient for rate control. He developed severe hypotension related to amiodarone and required inotropic support along with rapid-sequence intubation.
  
  
  CONCLUSIONS
  Intravenous amiodarone can cause severe and refractory hypotension.
authors.affiliation: Director of Medical Service, Roma Hospital, Roma, QLD, Australia.
authors.forename: Deepak
authors.initials: D
authors.lastname: Doshi
authors.affiliation: Department of Emergency, Campbelltown Hospital, Campbelltown, NSW, Australia.
authors.forename: Ravi
authors.initials: R
authors.lastname: Jayawardana
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D006801:Humans; D007022:Hypotension / Q000139:chemically induced*; D008297:Male
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone