title: Dysregulation in Youth with Anxiety Disorders: Relationship to Acute and 7- to 19- Year Follow-Up Outcomes of Cognitive-Behavioral Therapy.
abstract: This study evaluated the impact of dysregulation across cognitive, affective, and behavioral domains on acute and 7- to 19-year follow-up outcomes of cognitive-behavioral therapy (CBT) for anxiety, and explored dysregulation as a predictor of psychopathology and impairment in young adulthood among individuals who received anxiety treatment as youth. Participants (N = 64; 50 % female, 83 % non-Hispanic White) from two randomized clinical trials completed a follow-up assessment 7-19 years later. Latent profile analysis identified dysregulation based on Anxious/Depressed, Attention Problems, and Aggressive Behavior scores on the Child Behavior Checklist. Although pretreatment dysregulation was not related to acute or follow-up outcomes for anxiety diagnoses that were the focus of treatment, dysregulation predicted an array of non-targeted psychopathology at follow-up. Among youth with a principal anxiety disorder, the effects of CBT (Coping Cat) appear to be robust against broad impairments in self-regulation. However, youth with a pretreatment dysregulation profile likely need follow-up to monitor for the emergence of other disorders.
authors.affiliation: Department of Psychology, Georgia State University, P.O. Box 5010, Atlanta, GA, 30302-5010, USA. ncaporino@gsu.edu.
authors.forename: Nicole E
authors.initials: NE
authors.lastname: Caporino
authors.affiliation: Department of Couple and Family Therapy, Drexel University, Philadelphia, Pennsylvania.
authors.forename: Joanna
authors.initials: J
authors.lastname: Herres
authors.affiliation: Department of Psychology, Temple University, Philadelphia, Pennsylvania.
authors.forename: Philip C
authors.initials: PC
authors.lastname: Kendall
authors.affiliation: Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Courtney Benjamin
authors.initials: CB
authors.lastname: Wolk
mesh_terms: D000293:Adolescent; D000328:Adult; D000339:Affect; D000374:Aggression / Q000523:psychology; D001007:Anxiety / Q000523:psychology / Q000628:therapy*; D001008:Anxiety Disorders / Q000523:psychology / Q000628:therapy*; D002648:Child; D003071:Cognition; D015928:Cognitive Behavioral Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016896:Treatment Outcome
keywords: Adolescents; Anxiety; Children; Dysregulation; Self-regulation; Treatment