title: A hybridisation-dependent membrane-insertable amphiphilic DNA.
abstract: We synthesised a novel membrane-insertable amphiphilic DNA. The amphiphilic DNA had a nine-nucleotide hydrophobic region at one end consisting of octyl phosphotriester linkages. The amphiphilic DNA bound to the lipid membrane by inserting the hydrophobic region; this process was facilitated by the presence of the complementary DNA strand.
authors.affiliation: Regulatory Bioorganic Chemistry, The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihoga-oka, Ibaraki 567-0047, Japan. cdohno@sanken.osaka-u.ac.jp nakatani@sanken.osaka-u.ac.jp.
authors.forename: C
authors.initials: C
authors.lastname: Dohno
authors.forename: K
authors.initials: K
authors.lastname: Matsuzaki
authors.forename: H
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: T
authors.initials: T
authors.lastname: Shibata
authors.forename: K
authors.initials: K
authors.lastname: Nakatani
mesh_terms: D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D008055:Lipids / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry; D015394:Molecular Structure; D013501:Surface-Active Agents / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D004952:Esters; D008055:Lipids; D008081:Liposomes; D013501:Surface-Active Agents; D004247:DNA