title: Decreased mean platelet volume is associated with the developing stage of fetoplacental unit in spontaneous abortion.
abstract: OBJECTIVE
  The aim was to evaluate the place of mean platelet volume (MPV) in predicting spontaneous miscarriage and to identify any differences in its values following miscarriage after biochemical and clinical pregnancy.
  
  
  METHODS
  We retrospectively evaluated the data of 305 spontaneous miscarriages and 168 control subjects. The miscarriage subjects were evaluated in two groups: miscarriage after biochemical pregnancy (n=79) (BA group) and miscarriage after clinical pregnancy (n=226) (CA group). Demographic and laboratory data of all subjects were statistically compared.
  
  
  RESULTS
  No statistically significant difference was found between the miscarriage and control subjects in terms of demographic data and Hb, Htc, WBC, and Plt values. The mean platelet volume (MPV) value in the miscarriage group (8.99±1.47 fl) was statistically significantly lower than in the control group (9.66±1.64 fl) (P<0.001). A statistically significant difference was present between the BA, CA and control group, with the lowest MPV value in the BA group (8.64±1.34 fl, 9.11±1.49 fl, and 9.66±1.64 fl, respectively) (P<0.001).
  
  
  CONCLUSIONS
  MPV was significantly lower in patients with miscarriage than the control group, and this was correlated with the gestational stage when the miscarriage occurred.
authors.affiliation: Department of Obstetric and Gynecology, Adiyaman University School of Medicine Adiyaman, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kaplanoglu
authors.affiliation: Department of Obstetric and Gynecology, Division of Perinatology, Ankara University School of Medicine Ankara, Turkey.
authors.forename: Tuncay
authors.initials: T
authors.lastname: Yuce
authors.affiliation: Department of Obstetric and Gynecology, Adiyaman University School of Medicine Adiyaman, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bulbul
keywords: Mean platelet volume; biochemical abortion; clinic abortion; prediction