title: Can ficolin-2 (L-ficolin) insufficiency be established by a single serum protein measurement?
abstract: Serum ficolin-2 was measured in multiple (2-27) samples from 68 paediatric sepsis patients. Fourteen individuals (21%) gave values that included a change in status from 'normal' to 'insufficient' or vice versa. Therefore, if possible, ficolin-2 concentration should be determined in samples obtained when a disease is inactive.
authors.affiliation: Scottish National Blood Transfusion Service, National Science Laboratory, Edinburgh, UK.
authors.forename: D C
authors.initials: DC
authors.lastname: Kilpatrick
authors.affiliation: Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland.
authors.forename: A S
authors.initials: AS
authors.lastname: Świerzko
authors.affiliation: Department of Anesthesiology and Intensive Therapy, Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Sobociński
authors.affiliation: Department of Anesthesiology and Intensive Therapy, Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Krajewski
authors.affiliation: Department of Newborns' Infectious Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Chojnacka
authors.affiliation: Department of Newborns' Infectious Diseases, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Szczapa
authors.affiliation: Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Cedzyński
mesh_terms: D015415:Biomarkers; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D037102:Lectins / Q000097:blood*; D008297:Male; D015203:Reproducibility of Results; D018805:Sepsis / Q000097:blood / Q000175:diagnosis / Q000235:genetics; D000097604:Ficolins
chemical_list: D015415:Biomarkers; D037102:Lectins; D000097604:Ficolins