title: The International Mouse Strain Resource (IMSR): cataloging worldwide mouse and ES cell line resources.
abstract: The availability of and access to quality genetically defined, health-status known mouse resources is critical for biomedical research. By ensuring that mice used in research experiments are biologically, genetically, and health-status equivalent, we enable knowledge transfer, hypothesis building based on multiple data streams, and experimental reproducibility based on common mouse resources (reagents). Major repositories for mouse resources have developed over time and each has significant unique resources to offer. Here we (a) describe The International Mouse Strain Resource that offers users a combined catalog of worldwide mouse resources (live, cryopreserved, embryonic stem cells), with direct access to repository sites holding resources of interest and (b) discuss the commitment to nomenclature standards among resources that remain a challenge in unifying mouse resource catalogs.
authors.affiliation: Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. janan.eppig@jax.org.
authors.forename: Janan T
authors.initials: JT
authors.lastname: Eppig
authors.affiliation: Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. howie.motenko@jax.org.
authors.forename: Howie
authors.initials: H
authors.lastname: Motenko
authors.affiliation: Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. joel.richardson@jax.org.
authors.forename: Joel E
authors.initials: JE
authors.lastname: Richardson
authors.affiliation: Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. beverly.richards-smith@jax.org.
authors.forename: Beverly
authors.initials: B
authors.lastname: Richards-Smith
authors.affiliation: Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA. cynthia.smith@jax.org.
authors.forename: Cynthia L
authors.initials: CL
authors.lastname: Smith
mesh_terms: D000818:Animals; D035843:Biomedical Research; D002376:Cataloging; D002460:Cell Line / Q000145:classification*; D053595:Embryonic Stem Cells / Q000145:classification*; D006801:Humans; D020407:Internet; D051379:Mice; D008815:Mice, Inbred Strains / Q000145:classification*