title: Probing the stress and depression circuits with a disease gene.
abstract: Selectively deleting a gene that has been linked to depression from specific neurons in mice sheds new light on a neural circuit that controls stress-induced depressive behaviors.
authors.affiliation: Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.
authors.forename: Chang Sin
authors.initials: CS
authors.lastname: Park
authors.affiliation: Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States.
authors.forename: X William
authors.initials: XW
authors.lastname: Yang
mesh_terms: D000818:Animals; D003863:Depression; D005260:Female; D008297:Male; D017397:Prefrontal Cortex / Q000502:physiology*; D017966:Pyramidal Cells / Q000502:physiology*
keywords: anxiety; depression; medial prefrontal cortex; mouse; neuropsychiatric disorders; neuroscience; stress; wolfram syndrome