title: [Management of deep-vein thrombosis: A 2015 update].
abstract: Deep vein thrombosis (DVT) is a frequent and multifactor disease, with two major complications, post thrombotic syndrome and pulmonary embolism. Both transient (surgery, plaster immobilization, bed rest/hospitalization) and chronic/persistent (age, cancer, clinical or biological thrombophilia…) risk factors modulate treatment duration. Diagnostic management relies on clinical evaluations, probability followed by laboratory tests or imaging. So far, compression ultrasound is the diagnostic test of choice to make a positive diagnosis of DVT. Anticoagulants at therapeutic dose for at least 3 months constitute the cornerstones of proximal (i.e. involving popliteal or more proximal veins) DVT therapeutic management. The arrival of new oral anticoagulants should optimize ambulatory management of DVT.
authors.affiliation: Service de médecine vasculaire, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris cedex 15, France. Electronic address: emmanuel.messas@egp.aphp.fr.
authors.forename: E
authors.initials: E
authors.lastname: Messas
authors.affiliation: Service de médecine vasculaire, hôpital Brabois, CHU de Nancy, rue de Morvan, 54511 Vandœuvre-lès-Nancy cedex, France.
authors.forename: D
authors.initials: D
authors.lastname: Wahl
authors.affiliation: Service de médecine vasculaire, université Grenoble Alpes, CNRS/TIMC-IMAG UMR 5525/Themas, CHU de Grenoble, 38043 Grenoble cedex 09, France.
authors.forename: G
authors.initials: G
authors.lastname: Pernod
mesh_terms: D000553:Ambulatory Care; D000925:Anticoagulants / Q000145:classification / Q000627:therapeutic use; D003131:Combined Modality Therapy; D019468:Disease Management; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006760:Hospitalization; D006801:Humans; D007103:Immobilization; D008297:Male; D009369:Neoplasms / Q000150:complications; D010353:Patient Education as Topic; D054070:Postthrombotic Syndrome / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy; D012307:Risk Factors; D053828:Stockings, Compression; D017131:Thrombectomy; D019851:Thrombophilia / Q000150:complications / Q000188:drug therapy; D018608:Ultrasonography, Doppler / Q000379:methods; D020246:Venous Thrombosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*
chemical_list: D000925:Anticoagulants; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D
keywords: Anticoagulant; Deep vein thrombosis; Diagnosis; Diagnostic; Epidemiology; Thrombose veineuse profonde; Traitement; Treatment; Épidémiologie