title: Total Artificial Heart Bridge to Transplantation for a Patient With Occult Intracardiac Malignancy: Case Report.
abstract: Malignancy is the leading cause of long-term morbidity and mortality after heart and other solid organ transplantation; therefore, great emphasis is placed on pre- and post-transplantation cancer screening. Even with meticulous screening during evaluation for heart transplant candidacy, an occult cancer may not be apparent. Here, we share the case of a 51-year-old man with refractory heart failure who underwent total artificial heart implantation as a bridge to transplantation with the surprise finding of an isolated deposit of metastatic carcinoid tumor nested within a left ventricular papillary muscle in his explanted heart. The primary ileal carcinoid tumor was identified and resected completely. After remaining cancer-free for 14 months, he was listed for heart transplantation and was transplanted 2 months later. He is currently 3.5 months out from heart transplantation and doing well, without evidence of recurring malignancy.
authors.affiliation: Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California, United States.
authors.forename: H
authors.initials: H
authors.lastname: Reich
authors.affiliation: Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States.
authors.forename: L
authors.initials: L
authors.lastname: Czer
authors.affiliation: Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, California, United States.
authors.forename: S
authors.initials: S
authors.lastname: Bannykh
authors.affiliation: Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States.
authors.forename: M
authors.initials: M
authors.lastname: De Robertis
authors.affiliation: Department of Oncology, Cedars-Sinai Medical Center, Los Angeles, California, United States.
authors.forename: E
authors.initials: E
authors.lastname: Wolin
authors.affiliation: Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California, United States.
authors.forename: F
authors.initials: F
authors.lastname: Amersi
authors.affiliation: Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States.
authors.forename: J
authors.initials: J
authors.lastname: Moriguchi
authors.affiliation: Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States.
authors.forename: J
authors.initials: J
authors.lastname: Kobashigawa
authors.affiliation: Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States. Electronic address: Francisco.Arabia@cshs.org.
authors.forename: F
authors.initials: F
authors.lastname: Arabia
mesh_terms: D018278:Carcinoma, Neuroendocrine / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006333:Heart Failure / Q000209:etiology / Q000601:surgery*; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D016027:Heart Transplantation; D006352:Heart Ventricles; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged