title: The complete genome sequence of a high pristinamycin-producing strain Streptomyces pristinaespiralis HCCB10218.
abstract: Streptomyces pristinaespiralis produces the streptogramin-like antibiotic pristinamycin, which is a mixture of two structurally different components: pristinamycin I (PI) and pristinamycin II (PII). Herein, we report the complete genome sequence of a high pristinamycin-producing strain HCCB10218 (8.5 Mb) obtained by using PacBio RSII combined with Illumina HiSeq 2500 sequencing system. The genome sequence presented here provides clues for the mechanism underlying the higher pristinamycin production of HCCB10218.
authors.affiliation: Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, PR China.
authors.forename: Jinzhong
authors.initials: J
authors.lastname: Tian
authors.affiliation: Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, PR China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Yang
authors.affiliation: Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, PR China.
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.affiliation: Shanghai Laiyi Center for Biopharmaceuticals R&D, Shanghai 201203, PR China.
authors.forename: Lijun
authors.initials: L
authors.lastname: Ruan
authors.affiliation: Shanghai Laiyi Center for Biopharmaceuticals R&D, Shanghai 201203, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.affiliation: Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, PR China.
authors.forename: Guosong
authors.initials: G
authors.lastname: Zheng
authors.affiliation: Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, PR China.
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.affiliation: Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, PR China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Jiang
authors.affiliation: Shanghai Laiyi Center for Biopharmaceuticals R&D, Shanghai 201203, PR China. Electronic address: gemei@yeah.net.
authors.forename: Mei
authors.initials: M
authors.lastname: Ge
authors.affiliation: Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, PR China; Shanghai Collaborative Innovation Center for Biomanufacturing Technology, Shanghai 200237, PR China. Electronic address: yhlu@sibs.ac.cn.
authors.forename: Yinhua
authors.initials: Y
authors.lastname: Lu
mesh_terms: D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D016680:Genome, Bacterial / Q000235:genetics*; D025762:Pristinamycin / Q000378:metabolism*; D017422:Sequence Analysis, DNA; D013302:Streptomyces / Q000235:genetics* / Q000378:metabolism*
chemical_list: D004269:DNA, Bacterial; D025762:Pristinamycin
keywords: Genome sequence; Pristinamycin; Streptomyces pristinaespiralis