title: Detection of Epstein-Barr virus in leucoreduced blood products.
abstract: This study examined the prevalence of three human herpesviruses (HHV), namely HHV-4 (Epstein-Barr virus/EBV), HHV-6b and HHV-7 in leucoreduced blood products obtained from the Sainte-Justine Hospital blood bank. A total of 100 specimens, including 34 red blood cell concentrates, 33 platelet bags and 33 plasma units, were collected and screened by a sensitive PCR assay using virus-specific primers. Positive units were then retested by quantitative PCR. Of the 100 specimens, one platelet unit tested positive for EBV.
authors.affiliation: Department of Social and Preventive Medicine, Université de Montréal, Sainte-Justine Hospital, Montreal, QC, Canada.
authors.forename: H
authors.initials: H
authors.lastname: Trottier
authors.affiliation: Medical Affairs, Héma-Québec, Ville Saint-Laurent, QC, Canada.
authors.forename: G
authors.initials: G
authors.lastname: Delage
authors.affiliation: Research Center, Sainte-Justine Hospital, Montreal, QC, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Hu
authors.affiliation: Department of Pediatrics, Division of Hematology-Oncology, Sainte-Justine Hospital, Université de Montréal, Montreal, QC, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Robitaille
authors.affiliation: Department of Pediatrics, Division of Infectious Diseases, Sainte-Justine Hospital, Université de Montréal, Montreal, QC, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Buteau
authors.affiliation: Department of Pediatrics, Division of Pediatric Intensive Care Medicine, Sainte-Justine Hospital, Université de Montréal, Montreal, QC, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Tucci
authors.affiliation: Department of Pediatrics, Division of Pediatric Intensive Care Medicine, Sainte-Justine Hospital, Université de Montréal, Montreal, QC, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Lacroix
authors.affiliation: Department of Pediatrics, Division of Infectious Diseases, Sainte-Justine Hospital, Université de Montréal, Montreal, QC, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Alfieri
mesh_terms: D001771:Blood Banks / Q000592:standards / Q000706:statistics & numerical data*; D001773:Blood Cells / Q000821:virology; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D010949:Plasma / Q000821:virology*
keywords: herpesviruses; immunosuppression; leucoreduction; transfusion; transplant