title: Identification of a novel allele: DQB1*06:127 in Hispanic sisters.
abstract: Newly identified allele, HLA-DQB1*06:127, differs from DQB1*06:02:01 by the single nucleotide substitution 426C-A at codon 110 in exon 3.
authors.affiliation: McLendon Clinical Laboratory, UNC Hospitals, Chapel Hill, NC, USA.
authors.forename: T L
authors.initials: TL
authors.lastname: Crawford
authors.affiliation: McLendon Clinical Laboratory, UNC Hospitals, Chapel Hill, NC, USA.|Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
authors.forename: E T
authors.initials: ET
authors.lastname: Weimer
mesh_terms: D000483:Alleles; D019943:Amino Acid Substitution; D001483:Base Sequence; D016026:Bone Marrow Transplantation; D003001:Cloning, Molecular; D003062:Codon; D005091:Exons; D005260:Female; D005838:Genotype; D059866:HLA-DQ beta-Chains / Q000235:genetics* / Q000276:immunology; D006630:Hispanic or Latino; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D017354:Point Mutation; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D035781:Siblings; D066027:Transplant Recipients
chemical_list: D003062:Codon; D059866:HLA-DQ beta-Chains; C069051:HLA-DQB1 antigen
keywords: human leukocyte antigen; novel allele; sequence-based typing