title: Electrochemical detection of type 2 diabetes mellitus-related SNP via DNA-mediated growth of silver nanoparticles on single walled carbon nanotubes.
abstract: Herein, we proposed a new electrochemical sensing strategy for T2DM-related SNP detection via DNA-mediated growth of AgNPs on a SWCNT-modified electrode. Coupled with RNase HII enzyme assisted amplification, this approach could realize T2DM-related SNP assay and be applied in crude extracts of carcinoma pancreatic β-cell lines.
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410004, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Tao
authors.forename: Peng
authors.initials: P
authors.lastname: Zhao
authors.forename: Jing
authors.initials: J
authors.lastname: Zheng
authors.forename: Cuichen
authors.initials: C
authors.lastname: Wu
authors.forename: Muling
authors.initials: M
authors.lastname: Shi
authors.forename: Jishan
authors.initials: J
authors.lastname: Li
authors.forename: Yinhui
authors.initials: Y
authors.lastname: Li
authors.forename: Ronghua
authors.initials: R
authors.lastname: Yang
mesh_terms: D045744:Cell Line, Tumor; D004247:DNA / Q000737:chemistry*; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D055664:Electrochemical Techniques; D004566:Electrodes; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D020641:Polymorphism, Single Nucleotide; D016914:Ribonuclease H / Q000737:chemistry; D012834:Silver / Q000737:chemistry*
chemical_list: D037742:Nanotubes, Carbon; D012834:Silver; D004247:DNA; C091139:ribonuclease HII; D016914:Ribonuclease H