title: Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls.
abstract: Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis. In this study we investigated MIR146A SNPs in Chinese people with ankylosing spondylitis. Three common SNPs: rs2910164, rs2431697 and rs57095329 were selected and genotyped in 611 patients and 617 controls. We found no association between these SNPs and ankylosing spondylitis in our samples.
authors.affiliation: State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, No. 2005 Songhu Road, Shanghai, 200438, China; Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center and Shanghai Industrial Technology Institute (SITI), No. 250 Bibo Road, Shanghai, 201203, China.
authors.forename: Zhenmin
authors.initials: Z
authors.lastname: Niu
authors.affiliation: State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, No. 2005 Songhu Road, Shanghai, 200438, China.
authors.forename: Jiucun
authors.initials: J
authors.lastname: Wang
authors.affiliation: Division of Rheumatology, Huashan Hospital, Fudan University, No 12 Middle Wulumuqi Road, Shanghai, 200040, China.
authors.forename: Hejian
authors.initials: H
authors.lastname: Zou
authors.affiliation: Division of Rheumatology, Renji Hospital, Shanghai Jiaotong University, No 145 Middle Shandong Road, Shanghai, 200001, China.
authors.forename: Chengde
authors.initials: C
authors.lastname: Yang
authors.affiliation: Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center and Shanghai Industrial Technology Institute (SITI), No. 250 Bibo Road, Shanghai, 201203, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, No. 2005 Songhu Road, Shanghai, 200438, China.
authors.forename: Li
authors.initials: L
authors.lastname: Jin
mesh_terms: D044466:Asian People; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D035683:MicroRNAs / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D013167:Spondylitis, Ankylosing / Q000235:genetics*
chemical_list: C542542:MIRN146 microRNA, human; D035683:MicroRNAs