title: Hepatobiliary Schistosomiasis.
abstract: Schistosomiasis is an ancient parasitic disease that has afflicted Egyptians since the time of the pharaohs. The disease is caused by lodged schistosome eggs in the host liver, evoking an immune response and leading in some patients to the development of hepatic granuloma and fibrosis. Here, we review the epidemiology, immunopathogenesis, and clinical profile of schistosomiasis. This information may aid in the development of more efficacious treatments and improved disease prognosis.
authors.affiliation: Biochemistry Department, National Research Center, Cairo, Egypt.
authors.forename: Yehia
authors.initials: Y
authors.lastname: Shaker
authors.affiliation: Biochemistry Department, National Research Center, Cairo, Egypt.
authors.forename: Nervana
authors.initials: N
authors.lastname: Samy
authors.affiliation: Biochemistry Department, National Research Center, Cairo, Egypt.
authors.forename: Esmat
authors.initials: E
authors.lastname: Ashour
keywords: Anti-schistosomal vaccine; Co-infection and complications; Hepatosplenic schistosomiasis; Immunopathogenesis; Schistosomiasis