title: Valproic Acid-Induced Severe Acute Pancreatitis with Pseudocyst Formation: Report of a Case.
abstract: Valproic acid is the most widely used anti-epilep-tic drug in children, and it is probably the most frequent cause of drug-induced acute pancreatitis. Outcomes for patients with valproic acid-associated pancreatitis vary from full recovery after discontinuation of the drug to severe acute pancreatitis and death. Here, we present a case of valproic acid-induced severe acute pancreatitis with pseudocyst formation in a 10-year-old girl with cerebral palsy and generalized tonic-clonic seizure. There was no resolution of the pseudocyst after discontinuation of valproic acid. The patient became symptomatic with a progressive increase in the size of the pseudocyst. She was successfully treated with cystogastrostomy and was well at 12-month follow-up.
authors.affiliation: Surgical Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research.
authors.forename: Sukanta
authors.initials: S
authors.lastname: Ray
authors.affiliation: Surgical Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research.
authors.forename: Sujan
authors.initials: S
authors.lastname: Khamrui
authors.affiliation: Surgical Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research.
authors.forename: Mohnish
authors.initials: M
authors.lastname: Kataria
authors.affiliation: Surgical Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research.
authors.forename: Jayanta
authors.initials: J
authors.lastname: Biswas
authors.affiliation: Surgical Gastroenterology, School of Digestive and Liver Diseases, Institute of Postgraduate Medical Education and Research.
authors.forename: Suman
authors.initials: S
authors.lastname: Saha
keywords: cystogastrostomy; pancreatitis; pseudocyst; valproic acid