title: Nano-Snowflower of Gold Nanoparticles-Ruthenium Metallopolymer-Carbon Nanotubes Binding Anti-DNP IgE Antibody.
abstract: Gold nanoparticles (AuNPs) have been chemically functionalized onto multiwalled carbon nanotubes (MWCNT) through a metallopolymer linker-bis (2,2':6'2"-terpyridine) ruthenium(II)-connected diblock poly(N-isopropyacryamide). A "nano-snowflower" pattern was formed by self-assembly MWCNT-AuNP nanocomposite with anti-DNP IgE antibody. MWCNT-AuNP nanohybrid has unique biocompatibility and electronic current-voltage properties. This nanohybrid shows the potential application for IgE biosensor to diagnose cancer cells. We represent a step towards building complex electronic circuits response by providing molecular recognition properties.
authors.forename: Huayang
authors.initials: H
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
authors.forename: John M
authors.initials: JM
authors.lastname: Melnyczuk
authors.forename: Omotunde
authors.initials: O
authors.lastname: Olubi
authors.forename: Lauchon I
authors.initials: LI
authors.lastname: Lewis
authors.forename: Yang
authors.initials: Y
authors.lastname: Cao
authors.forename: Peri
authors.initials: P
authors.lastname: Nagappan
authors.forename: Shafiq A
authors.initials: SA
authors.lastname: Khan
authors.forename: Conrad W
authors.initials: CW
authors.lastname: Ingram
authors.forename: Issifu I
authors.initials: II
authors.lastname: Harruna
mesh_terms: D000327:Adsorption; D000911:Antibodies, Monoclonal / Q000737:chemistry / Q000276:immunology*; D003217:Conductometry / Q000295:instrumentation; D004553:Electric Conductivity; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006046:Gold / Q000737:chemistry*; D007118:Immunoassay / Q000295:instrumentation*; D007073:Immunoglobulin E / Q000032:analysis / Q000276:immunology*; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000737:chemistry*; D053761:Nanocomposites / Q000737:chemistry / Q000648:ultrastructure; D010316:Particle Size; D011485:Protein Binding; D012428:Ruthenium / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000911:Antibodies, Monoclonal; D007073:Immunoglobulin E; D006046:Gold; D012428:Ruthenium