title: Overcoming barriers to HPV vaccination: A randomized clinical trial of a culturally-tailored, media intervention among African American girls.
abstract: Although genital HPV is the most prevalent STI in the US, rates of vaccination uptake among high-risk subgroups remain low. Investigations of vaccine compliance have mainly targeted mother-daughter dyads, which in some settings may prove difficult. This study examines an innovative culturally tailored, computer-delivered media-based strategy to promote HPV vaccine uptake. Data, inclusive of sociodemographics, sexual behaviors, knowledge, attitudes, and beliefs about HPV and vaccination were collected via ACASI from 216 African American adolescent females (ages 14-18 years) seeking services in family planning and STI public health clinics in metropolitan Atlanta. Data were obtained prior to randomization and participation in an interactive media-based intervention designed to increase HPV vaccination uptake. Medical record abstraction was conducted 7 month post-randomization to assess initial vaccine uptake and compliance. Participants in the intervention were more compliant to vaccination relative to a placebo comparison condition (26 doses vs. Seventeen doses; p=0.12). However, vaccination series initiation and completion were lower than the national average. Thorough evaluation is needed to better understand factors facilitating HPV vaccine uptake and compliance, particularly perceived susceptibility and the influence of the patient-provider encounter in a clinical setting.
authors.affiliation: a Department of Behavioral Sciences and Health Education ; Emory University Rollins School of Public Health ; Atlanta , GA USA.|b Department of Pediatrics ; Division of Infectious Diseases, Epidemiology, and Immunology; Emory University School of Medicine ; Atlanta , GA USA.
authors.forename: Ralph J
authors.initials: RJ
authors.lastname: DiClemente
authors.affiliation: c ICF International ; Atlanta , GA USA.
authors.forename: Colleen Crittenden
authors.initials: CC
authors.lastname: Murray
authors.affiliation: d Office of Academic Advancement; Emory University Nell Hodgson Woodruff School of Nursing ; Atlanta , GA USA.
authors.forename: Tracie
authors.initials: T
authors.lastname: Graham
authors.affiliation: e Salud Para La Gente ; Watsonville , CA USA.
authors.forename: Julia
authors.initials: J
authors.lastname: Still
mesh_terms: D000293:Adolescent; D001741:Black or African American; D003146:Communications Media; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D030361:Papillomavirus Infections / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000627:therapeutic use*; D010349:Patient Compliance / Q000523:psychology*; D010353:Patient Education as Topic / Q000379:methods*; D012725:Sexual Behavior; D014481:United States; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control*; D014611:Vaccination / Q000706:statistics & numerical data
chemical_list: D053918:Papillomavirus Vaccines
keywords: HPV; adolescent; media intervention; vaccination uptake