title: Enantioselective addition of arylboronic acids to methyl 2-formylbenzoates by using a ruthenium/Me-BIPAM catalyst for synthesis of chiral 3-aryl-isobenzofuranones.
abstract: Ruthenium/Me-BIPAM-catalyzed asymmetric addition of arylboronic acids to methyl 2-formylbenzoates afforded chiral 3-aryl-isobenzofuranones. [RuCl2(p-cymene)]2/Me-BIPAM and RuCl2(PPh3)3/Me-BIPAM catalyst systems tolerate a variety of functional groups and give high yields with high enantioselectivities.
authors.affiliation: Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-8628, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Yohda
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D001565:Benzoates / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D000081007:Cymenes; D005663:Furans / Q000737:chemistry*; D008745:Methylation; D039821:Monoterpenes / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001565:Benzoates; D001897:Boronic Acids; D000081007:Cymenes; D005663:Furans; D039821:Monoterpenes; C007210:4-cymene; D012428:Ruthenium