title: Late gadolinium enhancement cardiac imaging on a 3T scanner with parallel RF transmission technique: prospective comparison of 3D-PSIR and 3D-IR.
abstract: OBJECTIVE
  To qualitatively and quantitatively compare different late gadolinium enhancement (LGE) sequences acquired at 3T with a parallel RF transmission technique.
  
  
  METHODS
  One hundred and sixty participants prospectively enrolled underwent a 3T cardiac MRI with 3 different LGE sequences: 3D Phase-Sensitive Inversion-Recovery (3D-PSIR) acquired 5 minutes after injection, 3D Inversion-Recovery (3D-IR) at 9 minutes and 3D-PSIR at 13 minutes. All LGE-positive patients were qualitatively evaluated both independently and blindly by two radiologists using a 4-level scale, and quantitatively assessed with measurement of contrast-to-noise ratio and LGE maximal surface. Statistical analyses were calculated under a Bayesian paradigm using MCMC methods.
  
  
  RESULTS
  Fifty patients (70 % men, 56yo ± 19) exhibited LGE (62 % were post-ischemic, 30 % related to cardiomyopathy and 8 % post-myocarditis). Early and late 3D-PSIR were superior to 3D-IR sequences (global quality, estimated coefficient IR > early-PSIR : -2.37 CI = [-3.46 ; -1.38], prob(coef > 0) = 0 % and late-PSIR > IR : 3.12 CI = [0.62 ; 4.41], prob(coef > 0) = 100 %), LGE surface estimated coefficient IR > early-PSIR: -0.09 CI = [-1.11; -0.74], prob(coef > 0) = 0 % and late-PSIR > IR : 0.96 CI = [0.77; 1.15], prob(coef > 0) = 100 %). Probabilities for late PSIR being superior to early PSIR concerning global quality and CNR were over 90 %, regardless of the aetiological subgroup.
  
  
  CONCLUSIONS
  In 3T cardiac MRI acquired with parallel RF transmission technique, 3D-PSIR is qualitatively and quantitatively superior to 3D-IR.
  
  
  CONCLUSIONS
  • Late gadolinium enhancement is an essential part of a cardiac MRI examination • PSIR and IR sequences are the two possible options for LGE imaging • At 3T with parallel RF transmission, PSIR sequences are significantly better • One LGE sequence is sufficient, allowing an optimization of the acquisition time.
authors.affiliation: Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg Cedex, France. groseillou@hotmail.com.|Service de Radiologie, Nouvel Hôpital Civil, 1 Place de l'Hôpital, 67091, Strasbourg Cedex, France. groseillou@hotmail.com.
authors.forename: Anthony
authors.initials: A
authors.lastname: Schultz
authors.affiliation: Cardiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg Cedex, France.
authors.forename: Thibault
authors.initials: T
authors.lastname: Caspar
authors.affiliation: Public Health and Biostatistics Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg Cedex, France.
authors.forename: Mickaël
authors.initials: M
authors.lastname: Schaeffer
authors.affiliation: Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg Cedex, France.
authors.forename: Aïssam
authors.initials: A
authors.lastname: Labani
authors.affiliation: Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg Cedex, France.
authors.forename: Mi-Young
authors.initials: MY
authors.lastname: Jeung
authors.affiliation: Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg Cedex, France.
authors.forename: Soraya
authors.initials: S
authors.lastname: El Ghannudi
authors.affiliation: Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg Cedex, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Roy
authors.affiliation: Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg Cedex, France.|iCube Laboratory, Université de Strasbourg / CNRS, UMR 7357, 67400, Illkirch, France.
authors.forename: Mickaël
authors.initials: M
authors.lastname: Ohana
mesh_terms: D000328:Adult; D000368:Aged; D001499:Bayes Theorem; D009202:Cardiomyopathies / Q000000981:diagnostic imaging*; D003287:Contrast Media; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging*; D009205:Myocarditis / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D011336:Probability; D011446:Prospective Studies
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C090600:gadobutrol
keywords: Cardiac imaging techniques; Late gadolinium enhancement; Magnetic resonance imaging; Parallel radiofrequency transmission; Phase-sensitive inversion recovery