title: Alpha-gal anaphylaxis: the first case report in Italy.
abstract: We report the case of a 55-year-old man who went into anaphylactic shock six hours after eating a meal containing meat. He reported having had several tick bites in months before the reaction. The serum specific IgE showed strong positivity to alpha-gal. This is clearly alpha-gal anaphylaxis with delayed onset after meat ingestion caused by tick bite, confirmed by alpha-gal IgE positivity.
authors.affiliation: Ospedale Castelli, Via Crocetta, 28921 Pallanza (VB), Italy. E-mail: marianna.calamari@libero.it.
authors.forename: A M
authors.initials: AM
authors.lastname: Calamari
authors.affiliation: Ambulatorio di Allergologia, Ospedale San Biagio, Domodossola (ASL VCO).
authors.forename: M
authors.initials: M
authors.lastname: Poppa
authors.affiliation: Allergologia e Immunologia Clinica, Ospedale S. Maria degli Angeli, Pordenone, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Villalta
authors.affiliation: Department of Internal Medicine, Clinical Allergy and Immunology, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Pravettoni
mesh_terms: D000707:Anaphylaxis / Q000209:etiology*; D004187:Disaccharides / Q000276:immunology*; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008460:Meat / Q000009:adverse effects*; D008875:Middle Aged; D064927:Tick Bites / Q000150:complications / Q000276:immunology*
chemical_list: D004187:Disaccharides; C055075:galactosyl-(1-3)galactose; D007073:Immunoglobulin E
keywords: Food allergy; Galactose-alpha-1,3-galactose (alpha-gal); delayed anaphylaxis; red meat