title: The complete mitochondrial genomes of five Eimeria species infecting domestic rabbits.
abstract: Rabbit coccidiosis caused by members of the genus Eimeria can cause enormous economic impact worldwide, but the genetics, epidemiology and biology of these parasites remain poorly understood. In the present study, we sequenced and annotated the complete mitochondrial (mt) genomes of five Eimeria species that commonly infect the domestic rabbits. The complete mt genomes of Eimeria intestinalis, Eimeria flavescens, Eimeria media, Eimeria vejdovskyi and Eimeria irresidua were 6261bp, 6258bp, 6168bp, 6254bp, 6259bp in length, respectively. All of the mt genomes consist of 3 genes for proteins (cytb, cox1, and cox3), 14 gene fragments for the large subunit (LSU) rRNA and 11 gene fragments for the small subunit (SSU) rRNA, but no transfer RNA (tRNA) genes. The gene order of the mt genomes is similar to that of Plasmodium, but distinct from Haemosporida and Theileria. Phylogenetic analyses based on full nucleotide sequences using Bayesian analysis revealed that the monophyly of the Eimeria of rabbits was strongly statistically supported with a Bayesian posterior probabilities. These data provide novel mtDNA markers for studying the population genetics and molecular epidemiology of the Eimeria species, and should have implications for the molecular diagnosis, prevention and control of coccidiosis in rabbits.
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China.
authors.forename: Guo-Hua
authors.initials: GH
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, PR China.
authors.forename: Si-Qin
authors.initials: SQ
authors.lastname: Tian
authors.affiliation: College of Animal Science and Technology, Hebei North University, Zhang Jiakou, Hebei Province 075000, PR China.
authors.forename: Ping
authors.initials: P
authors.lastname: Cui
authors.affiliation: College of Animal Science and Technology, Hebei North University, Zhang Jiakou, Hebei Province 075000, PR China.
authors.forename: Su-Fang
authors.initials: SF
authors.lastname: Fang
authors.affiliation: College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, PR China.
authors.forename: Chun-Ren
authors.initials: CR
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China; College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, PR China. Electronic address: xingquanzhu1@hotmail.com.
authors.forename: Xing-Quan
authors.initials: XQ
authors.lastname: Zhu
mesh_terms: D000818:Animals; D001483:Base Sequence; D001499:Bayes Theorem; D003048:Coccidiosis / Q000469:parasitology / Q000662:veterinary*; D004272:DNA, Mitochondrial / Q000737:chemistry; D016054:DNA, Protozoan / Q000737:chemistry; D004539:Eimeria / Q000145:classification / Q000235:genetics*; D054629:Genome, Mitochondrial; D018503:Genome, Protozoan / Q000235:genetics; D010802:Phylogeny; D011817:Rabbits / Q000469:parasitology*
chemical_list: D004272:DNA, Mitochondrial; D016054:DNA, Protozoan
keywords: Eimeria; Mitochondrial DNA; Mitochondrial genome; Rabbits