title: Digital breast tomosynthesis at screening assessment: are two views always necessary?
abstract: OBJECTIVE
  The current recommendation from the UK National Health Service Breast Screening Programme is that digital breast tomosynthesis (DBT) can be used for further assessment of possible screen-detected soft-tissue abnormalities in place of spot compression views and when used should be performed in two projections. The aim of the study was to assess whether two-view DBT is necessary if the abnormality is seen only in one view on initial full-field digital mammography (FFDM).
  
  
  METHODS
  617 cases with possible masses, distortions and asymmetrical densities visualized only in one view on screening FFDM were included. All of these females underwent two-view DBT, clinical examination and ultrasound. The FFDM and DBT findings on each view were compared and correlated with the histological diagnosis.
  
  
  RESULTS
  586 of 617 cases had normal or benign findings on further assessment, and no additional information was obtained on the other DBT view. There were 31 confirmed cancers. In 26 cases (84%), the cancer was seen on the corresponding DBT view. No cancer was seen on the other DBT view alone. Five cancers (16%) were not seen on either view on DBT owing to technical reasons. No cancers would have been missed if only the corresponding DBT view was performed.
  
  
  CONCLUSIONS
  Two-view DBT may not be necessary when used for further assessment of possible screen-detected soft-tissue abnormalities. Larger studies should be undertaken to investigate this further.
  
  
  CONCLUSIONS
  One-view DBT may be adequate in assessing soft-tissue abnormalities seen only on one FFDM view.
authors.affiliation: 1 Nightingale Centre and Genesis Prevention Centre, University Hospital South Manchester NHS Trust, Manchester, UK.
authors.forename: Rabea
authors.initials: R
authors.lastname: Haq
authors.affiliation: 1 Nightingale Centre and Genesis Prevention Centre, University Hospital South Manchester NHS Trust, Manchester, UK.|2 Centre for Imaging Sciences, Institute of Population Health, University of Manchester, Manchester, UK.
authors.forename: Yit Y
authors.initials: YY
authors.lastname: Lim
authors.affiliation: 1 Nightingale Centre and Genesis Prevention Centre, University Hospital South Manchester NHS Trust, Manchester, UK.|2 Centre for Imaging Sciences, Institute of Population Health, University of Manchester, Manchester, UK.
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Maxwell
authors.affiliation: 1 Nightingale Centre and Genesis Prevention Centre, University Hospital South Manchester NHS Trust, Manchester, UK.
authors.forename: Emma
authors.initials: E
authors.lastname: Hurley
authors.affiliation: 1 Nightingale Centre and Genesis Prevention Centre, University Hospital South Manchester NHS Trust, Manchester, UK.
authors.forename: Ursula
authors.initials: U
authors.lastname: Beetles
authors.affiliation: 1 Nightingale Centre and Genesis Prevention Centre, University Hospital South Manchester NHS Trust, Manchester, UK.
authors.forename: Sara
authors.initials: S
authors.lastname: Bundred
authors.affiliation: 1 Nightingale Centre and Genesis Prevention Centre, University Hospital South Manchester NHS Trust, Manchester, UK.
authors.forename: Mary
authors.initials: M
authors.lastname: Wilson
authors.affiliation: 2 Centre for Imaging Sciences, Institute of Population Health, University of Manchester, Manchester, UK.
authors.forename: Susan
authors.initials: S
authors.lastname: Astley
authors.affiliation: 3 Department of Radiology, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, UK.
authors.forename: Fiona J
authors.initials: FJ
authors.lastname: Gilbert
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D011856:Radiographic Image Enhancement / Q000379:methods*; D006113:United Kingdom