title: Stem Cell Therapy: Current Applications and Potential for Urology.
abstract: Stem cell therapy holds the potential to revolutionize the treatment of a number of chronic conditions. Stem cells ability to home in on injured sites of the body, stimulate angiogenesis, tissue regeneration, immunomodulation, anti-inflammatory, and anti-fibrotic factors have attracted their use in the treatment of many conditions. Urology has registered one of the highest experimental successes using stem cell therapy. However, the rate of clinical applications is comparatively lower. This review takes a look at our efforts so far and what needs to be done in order to maximize the clinical benefit we can derive from stem cells.
authors.affiliation: 3-007 Li Ka Shing Centre for Health Research Innovation, University of Alberta, Edmonton, AB, Canada, T6G 2E1. wiafe@ualberta.ca.
authors.forename: Bridget
authors.initials: B
authors.lastname: Wiafe
authors.affiliation: , 2C3.79 WMC, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada. pmetcalf@ualberta.ca.
authors.forename: Peter D
authors.initials: PD
authors.lastname: Metcalfe
authors.affiliation: 3-002E Li Ka Shing Centre for Health Research Innovation, University of Alberta, Edmonton, AB, Canada, T6G 2E1. adesida@ualberta.ca.
authors.forename: Adetola B
authors.initials: AB
authors.lastname: Adesida
mesh_terms: D000818:Animals; D005355:Fibrosis; D006801:Humans; D012038:Regeneration; D033581:Stem Cell Transplantation; D013234:Stem Cells; D023822:Tissue Engineering; D014570:Urologic Diseases / Q000473:pathology / Q000628:therapy*
keywords: Bladder obstruction; Immunomodulation; Mesenchymal; Renal fibrosis; Stem cells; Urinary incontinence