title: Copper-catalyzed C(sp(3))-H functionalization of ketones with vinyl azides: synthesis of substituted-1H-pyrroles.
abstract: Copper-catalyzed C(sp(3))-H functionalization of ketones with vinyl azides for the synthesis of substituted pyrroles has been developed. The method is a straightforward and efficient way to access a series of 2,3,5-trisubstituted-1H-pyrroles in modest to excellent yields with broad functional group tolerance under mild conditions.
authors.affiliation: Academy of Scientific & Innovative Research, Process Design & Engineering Cell, CSIR-Central Salt & Marine Chemicals Research Institute, G.B. Marg, Bhavnagar-364 002, Gujarat, India. adimurthy@csmcri.org.
authors.forename: Ramachandra Reddy
authors.initials: RR
authors.lastname: Donthiri
authors.forename: Supravat
authors.initials: S
authors.lastname: Samanta
authors.forename: Subbarayappa
authors.initials: S
authors.lastname: Adimurthy
mesh_terms: D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001386:Azides; D007659:Ketones; D009942:Organometallic Compounds; D011758:Pyrroles; D003300:Copper