title: A Survey on Synthesis Processes of Structured Materials for Biomedical Applications: Iron-based Magnetic Nanoparticles, Polymeric Materials and Polymerization Processes.
abstract: Magnetic materials based on iron oxides are extensively designed for several biomedical applications. Heterogeneous polymerization processes are powerful tools for the production of tailored micro-sized and nanosized magneto-polymeric particles. Although several polymerization processes have been adopted along the years, suspension, emulsion and miniemulsion systems deserve special attention due to its ability to produce spherical polymer particles containing magnetic nanoparticles homogeneously dispersed into the polymer thermoplastic matrices. The main objective of this paper is to review the main methods of synthesis of iron-based magnetic nanoparticles and to illustrate how typical polymerization processes in different dispersion medium can be successfully used to produce engineered magnetic core-shell structures. It is exemplified the use of suspension, emulsion and miniemulsion polymerization processes in order to support experimental methodologies required for the production of magnetic polymer particles intended for biomedical applications such as intravascular embolization treatments, drug delivery systems and hyperthermia treatment.
authors.forename: Weslany Silvério
authors.initials: WS
authors.lastname: Neto
authors.forename: Alan Thyago
authors.initials: AT
authors.lastname: Jensen
authors.forename: Gabriella Ribeiro
authors.initials: GR
authors.lastname: Ferreira
authors.forename: Leonardo Fonseca
authors.initials: LF
authors.lastname: Valadares
authors.forename: Rossano
authors.initials: R
authors.lastname: Gambetta
authors.forename: Sílvia Belém
authors.initials: SB
authors.lastname: Gonçalves
authors.affiliation: Institute of Chemistry, University of Brasília, P.O. Box: 04478, Zip Code: 70904-970, Brasília, DF, Brazil. fmachado@unb.br.
authors.forename: Fabricio
authors.initials: F
authors.lastname: Machado
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods; D006801:Humans; D007501:Iron / Q000008:administration & dosage / Q000737:chemistry*; D058185:Magnetite Nanoparticles / Q000008:administration & dosage / Q000737:chemistry*; D049329:Nanostructures / Q000008:administration & dosage / Q000737:chemistry*; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D010316:Particle Size; D058105:Polymerization; D011108:Polymers / Q000008:administration & dosage / Q000737:chemistry*
chemical_list: D058185:Magnetite Nanoparticles; D011108:Polymers; D007501:Iron