title: HIV control in postpartum mothers: a turbulent time.
abstract: We conducted an audit looking at the management of HIV-positive women in the postpartum period. We found that of the women with a previous AIDS-defining condition or a CD4 count <350 cells/µL, 83% were correctly continued on antiretroviral therapy (ART) and 84.1% of these had good virological control. ART was correctly stopped in 100% of women who had always had a CD4 count >500 cells/µL. A significant finding from our audit was that all of the women who had poor virological control or stopped ART against medical advice had social issues or self-reported depression. The main recommendation was to extend the pregnancy multidisciplinary team (MDT) meeting to include the 12-month postpartum period to offer support to women to try to improve treatment outcomes.
authors.affiliation: Directorate of Communicable Diseases, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK hannah.loftus@gmail.com.
authors.forename: Hannah
authors.initials: H
authors.lastname: Loftus
authors.affiliation: Directorate of Communicable Diseases, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: Alexander
authors.initials: A
authors.lastname: Burnett
authors.affiliation: Directorate of Communicable Diseases, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: Simone
authors.initials: S
authors.lastname: Naylor
authors.affiliation: Directorate of Communicable Diseases, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: Sylvia
authors.initials: S
authors.lastname: Bates
authors.affiliation: Directorate of Communicable Diseases, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: Julia
authors.initials: J
authors.lastname: Greig
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count; D003266:Continuity of Patient Care; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology*; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008485:Medical Audit; D009035:Mothers; D010349:Patient Compliance / Q000523:psychology* / Q000706:statistics & numerical data; D049590:Postpartum Period; D011247:Pregnancy; D012189:Retrospective Studies; D011795:Surveys and Questionnaires
chemical_list: D044966:Anti-Retroviral Agents
keywords: AIDS; Europe; HIV; PMTCT; adherence; antiretroviral therapy; postpartum; pregnancy; treatment; women