title: Paracoccidioidomycosis Mimicking Sarcoidosis: A Review of 8 Cases.
abstract: Sarcoidosis is a multisystem disorder that is characterized by noncaseous epithelioid cell granulomas, which may affect almost any organ. Thoracic involvement is common and accounts for most of the morbidity and mortality associated with this disease. The diagnosis is based on exhaustive exclusion of differential diagnoses, particularly granulomatous infections. We report data on eight patients with paracoccidioidomycosis mimicking sarcoidosis. Five patients presented with a chronic pulmonary type infection and three had a disseminated form after immunosuppressive treatment. The mycological diagnosis in noncaseating granulomas is emphasized and reviewed.
authors.affiliation: Programa de Pós-Graduação em Ciências Pneumológicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
authors.forename: Mariana Guimarães
authors.initials: MG
authors.lastname: Coelho
authors.affiliation: Laboratório de Micologia, Hospital Santa Rita, Irmandade Santa Casa de Misericórdia Porto Alegre (ISCMPA), Annes Dias 285, Porto Alegre, RS, 90020-090, Brazil.|Universidade Federal de Ciências da Saúde de Porto Alegre, UFCSPA, Porto Alegre, Brazil.
authors.forename: Cecília Bittencourt
authors.initials: CB
authors.lastname: Severo
authors.affiliation: Laboratório de Micologia, Hospital Santa Rita, Irmandade Santa Casa de Misericórdia Porto Alegre (ISCMPA), Annes Dias 285, Porto Alegre, RS, 90020-090, Brazil.
authors.forename: Flávio
authors.initials: F
authors.lastname: de Mattos Oliveira
authors.affiliation: Serviço de Radiologia, ISCMPA, Porto Alegre, RS, Brazil.
authors.forename: Bruno
authors.initials: B
authors.lastname: Hochhegger
authors.affiliation: Laboratório de Micologia, Hospital Santa Rita, Irmandade Santa Casa de Misericórdia Porto Alegre (ISCMPA), Annes Dias 285, Porto Alegre, RS, 90020-090, Brazil. severo@santacasa.tche.br.|Pós-Graduação em Ciências Pneumológicas, UFRGS, Pesquisador 1B CNPq, Porto Alegre, Brazil. severo@santacasa.tche.br.
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Severo
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects; D010229:Paracoccidioidomycosis / Q000175:diagnosis* / Q000382:microbiology / Q000401:mortality / Q000473:pathology*; D012507:Sarcoidosis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology*
chemical_list: D007166:Immunosuppressive Agents
keywords: Noncaseation granuloma; Paracoccidioides; Paracoccidioidomycosis; Sarcoidosis