title: Ovarian cancer in France: trends in incidence, mortality and survival, 1980-2012.
abstract: OBJECTIVE
  The aim of this epidemiological study was to describe the incidence, mortality and survival of ovarian cancer (OC) in France, according to age, period of diagnosis, and histological type.
  
  
  METHODS
  Incidence and mortality were estimated from 1980 to 2012 based on data in French cancer registries and from the Centre for Epidemiology of Causes of Death (CépiDc-Inserm) up to 2009. Net survival was estimated from registry data using the Pohar-Perme method, on cases diagnosed between 1989 and 2010, with date of last follow-up set at 30 June 2013.
  
  
  RESULTS
  In 2012, 4615 cases of OC were diagnosed in France, and 3140 women died from OC. World population age-standardized incidence and mortality rates declined by respectively 0.6% and 1.2% per year between 1980 and 2012. Net survival at 5years increased slightly, from 40% for the period 1989-1993 to 45% for the period 2005-2010. Net survival varied considerably according to histological type. Germ cell tumors had better net survival at 10years (81%) compared to epithelial tumors (32%), sex cord-stromal tumors (40%) and tumors without biopsy (8%).
  
  
  CONCLUSIONS
  Our study shows a decline in incidence and mortality rates from ovarian cancer in France between 1980 and 2012, but net survival remains poor overall, and improved only slightly over the whole study period.
authors.affiliation: Registre des tumeurs de l'Hérault, Montpellier, France. Electronic address: registre-tumeur@wanadoo.fr.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Trétarre
authors.affiliation: Registre des cancers de Loire-Atlantique-Vendée, Nantes, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Molinié
authors.affiliation: Registre des tumeurs du Doubs et du Territoire de Belfort, Besançon, France.
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Woronoff
authors.affiliation: Service de Biostatistiques, Hospices civils de Lyon, Lyon, France.
authors.forename: Nadine
authors.initials: N
authors.lastname: Bossard
authors.affiliation: Registre des tumeurs de l'Hérault, Montpellier, France.
authors.forename: Faiza
authors.initials: F
authors.lastname: Bessaoud
authors.affiliation: Registre des cancers du Haut-Rhin, Mulhouse, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Marrer
authors.affiliation: Registre des cancers du Tarn, Albi, France.
authors.forename: Pascale
authors.initials: P
authors.lastname: Grosclaude
authors.affiliation: Registre des tumeurs du Calvados, Caen, France.
authors.forename: Anne-Valérie
authors.initials: AV
authors.lastname: Guizard
authors.affiliation: Registre des cancers de l'Isère, Grenoble, France.
authors.forename: Patricia
authors.initials: P
authors.lastname: Delafosse
authors.affiliation: Registre des cancers de la Manche, Cherbourg, France.
authors.forename: Simona
authors.initials: S
authors.lastname: Bara
authors.affiliation: Registre des cancers du Bas- Rhin, Strasbourg, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Velten
authors.affiliation: Registre des cancers de la Somme, Amiens, France.
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Lapôtre-Ledoux
authors.affiliation: Registre des cancers de Lille et de sa zone de proximité, Lille, France.
authors.forename: Karine
authors.initials: K
authors.lastname: Ligier
authors.affiliation: Registre des cancers du Limousin, Limoges, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Léone
authors.affiliation: Registre des tumeurs gynécologique et du sein de Côte d'Or, Dijon, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Arveux
authors.affiliation: Institut de Veille Sanitaire, Service de biostatistiques des Hospices civils de Lyon, Lyon, France; Service de Biostatistiques, Hospices civils de Lyon, Lyon, France.
authors.forename: Zoé
authors.initials: Z
authors.lastname: Uhry
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000453:epidemiology* / Q000401:mortality; D000077216:Carcinoma, Ovarian Epithelial; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D009373:Neoplasms, Germ Cell and Embryonal / Q000453:epidemiology* / Q000401:mortality; D009375:Neoplasms, Glandular and Epithelial / Q000453:epidemiology* / Q000401:mortality; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000401:mortality; D012042:Registries; D018312:Sex Cord-Gonadal Stromal Tumors / Q000453:epidemiology* / Q000401:mortality; D015996:Survival Rate
keywords: Histological type; Incidence; Mortality; Ovarian cancer; Survival