title: Minimal Change Nephrotic Syndrome Which Was Most Likely Caused by Chronic Sinusitis.
abstract: A 33-year-old Japanese man was admitted with severe edema, and a renal biopsy confirmed minimal change nephrotic syndrome (MCNS). CT revealed his severe chronic sinusitis, and he first received antimicrobial therapy, which resulted in decreased proteinuria. The surgical operation for sinusitis resulted in the complete disappearance of proteinuria without corticosteroid or immunosuppressant therapy within one week. MCNS may be triggered by infection, but there are no previously reported cases of MCNS that is completely remitted by infection control alone. Therefore, we herein report the first case of MCNS that attained complete remission following therapy for chronic sinusitis alone, which suggests a strong etiology of chronic sinusitis for MCNS.
authors.affiliation: Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Japan.
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Iwatani
authors.forename: Daisuke
authors.initials: D
authors.lastname: Mori
authors.forename: Satoko
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Chikako
authors.initials: C
authors.lastname: Nakano
authors.forename: Ryohei
authors.initials: R
authors.lastname: Yamamoto
authors.forename: Chisako
authors.initials: C
authors.lastname: Masumura
authors.forename: Takashi
authors.initials: T
authors.lastname: Shikina
authors.forename: Takao
authors.initials: T
authors.lastname: Imai
authors.forename: Hidenori
authors.initials: H
authors.lastname: Inohara
authors.forename: Hiromi
authors.initials: H
authors.lastname: Rakugi
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Isaka
mesh_terms: D000328:Adult; D002908:Chronic Disease; D006801:Humans; D008297:Male; D009402:Nephrosis, Lipoid / Q000209:etiology*; D011507:Proteinuria / Q000209:etiology; D012074:Remission Induction; D012852:Sinusitis / Q000150:complications* / Q000601:surgery*