title: [Tuberculosis among patients in Israel with anti-TNF].
abstract: Treatment with anti-TNF increases the rate of the reactivation of latent tuberculosis (TB) infection. We present five case reports of patients who were treated with anti-TNF and developed active TB infection. Physicians should be aware of this possible complication and should conduct screening with the purified protein derivative test (PPD) or the interferon gamma release assay (IGRA) before anti-TNF treatment.
authors.forename: Atamna
authors.initials: A
authors.lastname: Ahmed
authors.forename: Alexander
authors.initials: A
authors.lastname: Guber
authors.forename: David
authors.initials: D
authors.lastname: Shitrit
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D059425:Interferon-gamma Release Tests; D007557:Israel / Q000453:epidemiology; D055985:Latent Tuberculosis / Q000175:diagnosis; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D014409:Tumor Necrosis Factor-alpha