title: Cobalt-Catalyzed Allylation of Heterobicyclic Alkenes: Ligand-Induced Divergent Reactivities.
abstract: The allylation of heterobicyclic alkenes is presented for the first time. By using an inexpensive cobalt salt as the catalyst and easy-to-handle potassium allyltrifluoroborate as the reagent, an unprecedented formal hydroallylation of the bicyclic alkenes is realized in high efficiency. When a chiral cobalt/bis(phosphine) complex is used instead, the alternative ring-opening products can be obtained in high yield and excellent enantioselectivity.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore) zhaoyu.science.nus.edu.sg.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore) zhaoyu.science.nus.edu.sg.
authors.forename: Chao
authors.initials: C
authors.lastname: Ma
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore) zhaoyu.science.nus.edu.sg.
authors.forename: Yi Xin
authors.initials: YX
authors.lastname: Lee
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore) zhaoyu.science.nus.edu.sg.
authors.forename: Rui-Zhi
authors.initials: RZ
authors.lastname: Huang
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543 (Singapore) zhaoyu.science.nus.edu.sg. zhaoyu@nus.edu.sg.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhao
keywords: P ligands; alkenes; allylic compounds; cobalt; synthetic methods