title: Design and In Vivo Test of a Batteryless and Fully Wireless Implantable Asynchronous Pacing System.
abstract: Goal: The aim of this study is to develop a novel fully wireless and batteryless technology for cardiac pacing.
  
  
  
  This technology uses radio frequency (RF) energy to power the implanted electrode in the heart. An implantable electrode antenna was designed for 1.2 GHz; then, it was tested in vitro and, subsequently, integrated with the rectifier and pacing circuit to make a complete electrode. The prototype implanted electrode was tested in vivo in an ovine subject, implanting it on the epicardial surface of the left ventricle. The RF energy, however, was transmitted to the implanted electrode using a horn antenna positioned 25 cm above the thorax of the sheep.
  
  
  
  It was demonstrated that a small implanted electrode can capture and harvest enough safe recommended RF energy to achieve pacing. Electrocardiogram signals were recorded during the experiments, which demonstrated asynchronous pacing achieved at three different rates.
  
  
  
  These results show that the proposed method has a great potential to be used for stimulating the heart and provides pacing, without requiring any leads or batteries. It hence has the advantage of potentially lasting indefinitely and may never require replacement during the life of the patient.
  
  
  
  The proposed method brings forward transformational possibilities in wireless cardiac pacing, and also in powering up the implantable devices.
authors.forename: Sajid M
authors.initials: SM
authors.lastname: Asif
authors.forename: Jared
authors.initials: J
authors.lastname: Hansen
authors.forename: Muhammad S
authors.initials: MS
authors.lastname: Khan
authors.forename: Scott D
authors.initials: SD
authors.lastname: Walden
authors.forename: Mark O
authors.initials: MO
authors.lastname: Jensen
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Braaten
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Ewert
mesh_terms: D000818:Animals; D004562:Electrocardiography; D004567:Electrodes, Implanted; D006801:Humans; D008954:Models, Biological; D010138:Pacemaker, Artificial; D011474:Prosthesis Design; D011846:Radio Waves; D012756:Sheep; D059015:Wireless Technology / Q000295:instrumentation*