title: When becomes more in fact less?
authors.forename: J André
authors.initials: JA
authors.lastname: Knottnerus
authors.forename: Peter
authors.initials: P
authors.lastname: Tugwell
mesh_terms: D035843:Biomedical Research / Q000191:economics; D002986:Clinical Trials as Topic; D006801:Humans; D012107:Research Design / Q000592:standards* / Q000706:statistics & numerical data