title: The growth of filaments under macromolecular confinement using scaling theory.
abstract: Quantitatively describing macromolecular confinement is still a challenge. Using the assembly of DNA tiles in a polyacrylamide network as a model, we studied the effect of macromolecular confinement on the growth of the filament by scaling theory. The results show that the confinement regulates the morphology, the initial growth rate v, and the eventual length of the filament Nm. The initial growth rate is dependent on the medium viscosity η as ν∝η(-0.94), and the filament adjusts its length in the given confined space as Nm∝ (ξ/Rg)(1.8), with ξ being the mesh size of the polyacrylamide solution and Rg being the radius of gyration of polyacrylamide.
authors.affiliation: Beijing National Laboratory for Molecular Sciences and the Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China. dliang@pku.edu.cn.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhu
authors.forename: Wei
authors.initials: W
authors.lastname: Pan
authors.forename: Xi
authors.initials: X
authors.lastname: Lu
authors.forename: Desheng
authors.initials: D
authors.lastname: Li
authors.forename: Jiang
authors.initials: J
authors.lastname: Zhao
authors.forename: Dehai
authors.initials: D
authors.lastname: Liang
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry; D007700:Kinetics; D046911:Macromolecular Substances / Q000138:chemical synthesis*; D008958:Models, Molecular; D000099166:Polyacrylamides
chemical_list: D000180:Acrylic Resins; D004247:DNA; D005456:Fluorescent Dyes; D046911:Macromolecular Substances; D000099166:Polyacrylamides