title: Pathology of Alcoholic Liver Disease.
abstract: Alcohol-attributable burden on global health is increasing, and the relationship between population alcohol consumption and liver-related deaths is strong. Longstanding scientific and clinical work has led to a relatively thorough, if not complete, understanding of the effects of alcohol consumption on the liver. Pathologic features of alcoholic liver disease (ALD) are recognized by pathologists and used to assist clinicians in diagnosing and determining severity of disease in patients suspected of ALD. In this review, we discuss the pathologic manifestations of ALD and provide salient points on their pathophysiology. In addition, the benefits and indications of liver biopsy and important differential diagnoses, including features distinguishing these entities, are reviewed.
authors.affiliation: Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: Romulo
authors.initials: R
authors.lastname: Celli
authors.affiliation: Pathology and Laboratory Service, VA Connecticut Health System and Department of Pathology, Yale University School of Medicine, West Haven, CT, USA.
authors.forename: Xuchen
authors.initials: X
authors.lastname: Zhang
keywords: Alcoholic liver disease; Pathology; Steatohepatitis; Steatosis