title: Comparison of obese adults with poor versus good sleep quality during a functional neuroimaging delay discounting task: A pilot study.
abstract: This study aimed to determine if obese adults with poor versus good sleep quality demonstrate reduced self-regulatory capacity and different patterns of neural activation when making impulsive monetary choices. Six obese, good quality sleepers (M age=44.7 years, M BMI=38.1 kg/m(2)) were compared to 13 obese, poor quality sleepers (M age=42.6, M BMI=39.2 kg/m(2)) on sleep and eating behavior and brain activation in prefrontal and insular regions while engaging in a delay discounting task during functional magnetic resonance imaging (fMRI). Poor quality sleepers demonstrated significantly lower brain activation in the right inferior frontal gyrus, right middle frontal gyrus, and bilateral insula when making immediate and smaller (impulsive) monetary choices compared to the baseline condition. Behaviorally, poor compared to good quality sleepers reported higher scores in the night eating questionnaire. Obese adults with poor sleep quality demonstrate decreased brain activation in multiple regions that regulate cognitive control and interceptive awareness, possibly reducing self-regulatory capacity when making immediately gratifying decisions.
authors.affiliation: Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, United States.
authors.forename: Laura E
authors.initials: LE
authors.lastname: Martin
authors.affiliation: Department of Psychology, University of Missouri Kansas City, Kansas City, MO, United States.
authors.forename: Lauren
authors.initials: L
authors.lastname: Pollack
authors.affiliation: Department of Psychology, University of Missouri Kansas City, Kansas City, MO, United States.
authors.forename: Ashley
authors.initials: A
authors.lastname: McCune
authors.affiliation: Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, United States; Department of Psychology, University of Michigan, Ann Arbor, MI, United States.
authors.forename: Erica
authors.initials: E
authors.lastname: Schulte
authors.affiliation: Center for Health Behavior Neuroscience, University of Kansas Medical Center, Kansas City, KS, United States.
authors.forename: Cary R
authors.initials: CR
authors.lastname: Savage
authors.affiliation: Department of Psychology, University of Missouri Kansas City, Kansas City, MO, United States. Electronic address: lundgrenj@umkc.edu.
authors.forename: Jennifer D
authors.initials: JD
authors.lastname: Lundgren
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000503:physiopathology*; D002755:Choice Behavior / Q000502:physiology; D065786:Delay Discounting / Q000502:physiology*; D005260:Female; D059907:Functional Neuroimaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D009765:Obesity / Q000150:complications / Q000503:physiopathology* / Q000523:psychology; D010865:Pilot Projects; D012890:Sleep / Q000502:physiology*; D007319:Sleep Initiation and Maintenance Disorders / Q000150:complications / Q000503:physiopathology* / Q000523:psychology; D013997:Time Factors; D055815:Young Adult
keywords: Brain activation; Delay discounting; Obesity; Self-regulation; Sleep quality