title: Supervised Learning Based Hypothesis Generation from Biomedical Literature.
abstract: Nowadays, the amount of biomedical literatures is growing at an explosive speed, and there is much useful knowledge undiscovered in this literature. Researchers can form biomedical hypotheses through mining these works. In this paper, we propose a supervised learning based approach to generate hypotheses from biomedical literature. This approach splits the traditional processing of hypothesis generation with classic ABC model into AB model and BC model which are constructed with supervised learning method. Compared with the concept cooccurrence and grammar engineering-based approaches like SemRep, machine learning based models usually can achieve better performance in information extraction (IE) from texts. Then through combining the two models, the approach reconstructs the ABC model and generates biomedical hypotheses from literature. The experimental results on the three classic Swanson hypotheses show that our approach outperforms SemRep system.
authors.affiliation: College of Computer Science and Engineering, Dalian University of Technology, Dalian 116024, China.
authors.forename: Shengtian
authors.initials: S
authors.lastname: Sang
authors.affiliation: College of Computer Science and Engineering, Dalian University of Technology, Dalian 116024, China.
authors.forename: Zhihao
authors.initials: Z
authors.lastname: Yang
authors.affiliation: College of Computer Science and Engineering, Dalian University of Technology, Dalian 116024, China.
authors.forename: Zongyao
authors.initials: Z
authors.lastname: Li
authors.affiliation: College of Computer Science and Engineering, Dalian University of Technology, Dalian 116024, China.
authors.forename: Hongfei
authors.initials: H
authors.lastname: Lin
mesh_terms: D000465:Algorithms; D057225:Data Mining; D006801:Humans; D008492:Medical Informatics Computing; D009323:Natural Language Processing; D011642:Publications