title: Age-related differences in hair trace elements: a cross-sectional study in Orenburg, Russia.
abstract: BACKGROUND
  Age-related differences in the trace element content of hair have been reported. However, some discrepancies in the data exist.
  
  
  OBJECTIVE
  The primary objective of this study was to estimate the change in hair trace elements content in relation to age.
  
  
  METHODS
  Six hundred and eighteen women and 438 men aged from 10-59 years took part in the current cross-sectional study.
  
  
  CONCLUSIONS
  Hair Cr, Mn, Ni, Si, Al, As, Be, Cd and Pb tended to decrease with age in the female sample, whereas hair Cu, Fe, I, Se, Li and Sn were characterised by an age-associated increase. Hair levels of Cr, Cu, I, Mn, Ni, Si and Al in men decreased with age, whereas hair Co, Fe, Se, Cd, Li and Pb content tended to increase. Hair mercury increased in association with age in men and in women, whereas hair vanadium was characterised by a significant decrease in both sexes. The difference in hair trace element content between men and women decreased with age. These data suggest that age-related differences in trace element status may have a direct implication in the ageing process.
authors.affiliation: a Russian Society of Trace Elements in Medicine, ANO "Centre for Biotic Medicine" , Moscow , Russia .|b Institute of Bioelementology (Russian Satellite Centre of Trace Element - Institute for UNESCO), Orenburg State University , Orenburg , Russia .
authors.forename: Margarita G
authors.initials: MG
authors.lastname: Skalnaya
authors.affiliation: a Russian Society of Trace Elements in Medicine, ANO "Centre for Biotic Medicine" , Moscow , Russia .|c Laboratory of Biotechnology and Applied Bioelementology , P. G. Demidov Yaroslavl State University , Yaroslavl , Russia , and.|d Department of Biochemistry , Orenburg State Medical University , Orenburg , Russia.
authors.forename: Alexey A
authors.initials: AA
authors.lastname: Tinkov
authors.affiliation: a Russian Society of Trace Elements in Medicine, ANO "Centre for Biotic Medicine" , Moscow , Russia .
authors.forename: Vasily A
authors.initials: VA
authors.lastname: Demidov
authors.affiliation: a Russian Society of Trace Elements in Medicine, ANO "Centre for Biotic Medicine" , Moscow , Russia .
authors.forename: Eugeny P
authors.initials: EP
authors.lastname: Serebryansky
authors.affiliation: a Russian Society of Trace Elements in Medicine, ANO "Centre for Biotic Medicine" , Moscow , Russia .|d Department of Biochemistry , Orenburg State Medical University , Orenburg , Russia.
authors.forename: Alexandr A
authors.initials: AA
authors.lastname: Nikonorov
authors.affiliation: a Russian Society of Trace Elements in Medicine, ANO "Centre for Biotic Medicine" , Moscow , Russia .|b Institute of Bioelementology (Russian Satellite Centre of Trace Element - Institute for UNESCO), Orenburg State University , Orenburg , Russia .|c Laboratory of Biotechnology and Applied Bioelementology , P. G. Demidov Yaroslavl State University , Yaroslavl , Russia , and.
authors.forename: Anatoly V
authors.initials: AV
authors.lastname: Skalny
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006197:Hair / Q000737:chemistry*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012426:Russia; D012727:Sex Characteristics; D018709:Statistics, Nonparametric; D014131:Trace Elements / Q000032:analysis*; D055815:Young Adult
chemical_list: D014131:Trace Elements
keywords: Age; hair; mercury; trace elements; vanadium