title: Synthesis of Pyrano[3,2-c]pyrazol-7(1H)-one Derivatives by Tandem Cyclization of 2-Diazo-3,5-dioxo-6-ynoates (Ynones).
abstract: The construct of the core of pyrano[3,2-c]pyrazol-7(1H)-one derivatives is realized. The key step includes a tandem cyclization, namely, a metal-free cascade 6-π electrocyclic ring closure-Michael reaction of 2-diazo-3,5-dioxo-6-ynoates (ynones). The cascade reaction cleanly generated the desired products in excellent yields under mild conditions.
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China) and Key Laboratory of the Assembly and Application of Organic Functional Molecules, Hunan Normal University , Changsha 410081, China.
authors.forename: Guisheng
authors.initials: G
authors.lastname: Deng
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China) and Key Laboratory of the Assembly and Application of Organic Functional Molecules, Hunan Normal University , Changsha 410081, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China) and Key Laboratory of the Assembly and Application of Organic Functional Molecules, Hunan Normal University , Changsha 410081, China.
authors.forename: Shengle
authors.initials: S
authors.lastname: Lu
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education of China) and Key Laboratory of the Assembly and Application of Organic Functional Molecules, Hunan Normal University , Changsha 410081, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Cheng