title: Polyketides from mantis-associated fungus Daldinia eschscholzii IFB-TL01.
abstract: Three new polyketides, named daldinone F (1), nodulisporin G (2), and dalmanol C (3), together with five known compounds, 4-8, were isolated from cultures of Daldinia eschscholzii. The structures of the new compounds were elucidated by extensive NMR and MS analyses. Compound 1 showed moderate cytotoxic activity against SW480 cancer cells with an IC50 value of 9.59 μM, and its absolute configuration was determined by single crystal X-ray diffraction.
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
authors.forename: Gang
authors.initials: G
authors.lastname: Wang
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
authors.forename: Jing-Yang
authors.initials: JY
authors.lastname: Fan
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Zhang
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
authors.forename: Cheng-Pin
authors.initials: CP
authors.lastname: Hua
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
authors.forename: Chao-Jun
authors.initials: CJ
authors.lastname: Chen
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
authors.forename: Wei
authors.initials: W
authors.lastname: Yan
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
authors.forename: Hui-Ming
authors.initials: HM
authors.lastname: Ge
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201). rhjiao@nju.edu.cn.
authors.forename: Rui-Hua
authors.initials: RH
authors.lastname: Jiao
authors.affiliation: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
authors.forename: Ren-Xiang
authors.initials: RX
authors.lastname: Tan
mesh_terms: D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D061065:Polyketides / Q000032:analysis*; D013098:Xylariales / Q000737:chemistry*
chemical_list: D061065:Polyketides
keywords: Cytotoxic activity; Daldinia eschscholzii; Polyketides; Radical coupling