title: [Innovations in diagnosis and treatment about a case of primary failure eruption linked to a PTHR1 gene mutation].
abstract: Primary failure of eruption is a rare condition marked by non-eruption of the posterior teeth due to mutation of a gene responsible for tooth eruption. Today, this anomaly can be detected early using innovative 3D-imaging techniques. Genetic and histologic testing will confirm the diagnosis and unfavorable prognosis. Alveolar growth must be followed in other areas too in order to avoid structural and functional asymmetry. An analysis of the diagnostic and therapeutic options using bone-borne anchorage is presented via the long-term monitoring of a female patient presenting primary failure of eruption linked to mutation of the PTHR1 gene.
authors.affiliation: Département d'Orthodontie, Faculté d'Odontologie de Lyon, 11 rue Guillaume Paradin, 69372 Lyon Cedex 08, France.
authors.forename: Monique
authors.initials: M
authors.lastname: Raberin
authors.affiliation: Département d'Orthodontie, Faculté d'Odontologie de Lyon, 11 rue Guillaume Paradin, 69372 Lyon Cedex 08, France.
authors.forename: Caroline
authors.initials: C
authors.lastname: Diesmusch
authors.affiliation: Département de Génétique, Hôpital Lyon-Est, 28 avenue Doyen Lépine, 69500 Bron, France.
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: Cordier
authors.affiliation: Département de Sciences Biologiques, Faculté d'Odontologie de Lyon, 11 rue Guillaume Paradin, 69008 Lyon, France - Institut de Génomique Fonctionnelle de Lyon (UMR5242), 46 allée d'Italie, 69364 Lyon cedex 07, France.
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Farges
mesh_terms: D000539:Alveolar Process / Q000254:growth & development; D001641:Bicuspid / Q000473:pathology; D002648:Child; D015921:Dental Implants; D042241:Early Diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008963:Molar / Q000601:surgery; D009154:Mutation / Q000235:genetics*; D052280:Orthodontic Anchorage Procedures / Q000295:instrumentation / Q000379:methods; D010347:Patient Care Planning; D044168:Receptor, Parathyroid Hormone, Type 1 / Q000235:genetics*; D020254:Tooth Ankylosis / Q000601:surgery; D014076:Tooth Diseases / Q000235:genetics* / Q000628:therapy; D014078:Tooth Eruption / Q000235:genetics*; D014087:Tooth Movement Techniques / Q000295:instrumentation / Q000379:methods
chemical_list: D015921:Dental Implants; C473449:PTH1R protein, human; D044168:Receptor, Parathyroid Hormone, Type 1