title: Oncoplastic reduction mammoplasty for breast cancer in women with macromastia: Oncological long-term outcomes.
abstract: OBJECTIVE
  To evaluate the long-term results of tumorectomy and concomitant bilateral oncoplastic reduction mammoplasty (ORM) for early stage breast cancer patients with macromastia in terms of local disease control and long-term oncological results.
  
  
  METHODS
  Data of 82 patients with macromastia undergoing ORM for breast cancer between 1996 and 2011 were retrospectively examined and evaluated with regard to oncological results.
  
  
  RESULTS
  The median age was 50 years. The median follow-up was 121 months (range 28-212 months). The median breast volume was 1402 cm3and the median weight of excised breast material was 679 g. The median surgical margin was 16 mm. Ten-year local recurrence rate was 8.7%. The 10-year overall survival rate was 82.2% and the disease-free survival rate was 73.2%. Early and late complication rates were 12.2% and 14.6%, respectively.
  
  
  CONCLUSIONS
  From the standpoint of local disease control and long-term observation, ORM can be considered a very safe and acceptable treatment for early stage breast cancer in women with macromastia.
authors.affiliation: Tepecik Training and Research Hospital, Department of General Surgery, Izmir, Turkey. Electronic address: musemiroglu@gmail.com.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Emiroglu
authors.affiliation: Tepecik Training and Research Hospital, Department of General Surgery, Izmir, Turkey.
authors.forename: Semra
authors.initials: S
authors.lastname: Salimoglu
authors.affiliation: Tepecik Training and Research Hospital, Department of General Surgery, Izmir, Turkey.
authors.forename: Cem
authors.initials: C
authors.lastname: Karaali
authors.affiliation: Tepecik Training and Research Hospital, Department of General Surgery, Izmir, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Sert
authors.affiliation: Su Private Hospital, Department of General Surgery, Izmir, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Gungor
authors.affiliation: Ege University, Medical School, Department of Radiation Oncology, Izmir, Turkey.
authors.forename: Fatma
authors.initials: F
authors.lastname: Sert
authors.affiliation: Tepecik Training and Research Hospital, Department of General Surgery, Izmir, Turkey.
authors.forename: Cengiz
authors.initials: C
authors.lastname: Aydın
mesh_terms: D000328:Adult; D000368:Aged; D001940:Breast / Q000002:abnormalities* / Q000601:surgery; D001943:Breast Neoplasms / Q000150:complications / Q000401:mortality / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000401:mortality / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000150:complications / Q000401:mortality / Q000601:surgery*; D018275:Carcinoma, Lobular / Q000150:complications / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006984:Hypertrophy / Q000150:complications / Q000601:surgery*; D016462:Mammaplasty / Q000379:methods*; D015412:Mastectomy, Segmental; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: breast cancer; cosmesis; macromastia; oncoplastic breast reduction; satisfaction