title: Yttrium-90 microsphere radioembolotherapy in a patient with spontaneously ruptured hepatocellular carcinoma.
abstract: Spontaneous rupture of hepatocellular carcinoma (HCC) is a potentially fatal presentation of the disease. Although many options for treatment exist, Yttrium-90 transcatheter arterial radioembolization has not previously been reported. We report a case of a 92-year-old woman found to have a ruptured HCC treated with radioembolization that showed no viable tumor and no extrahepatic disease at 2 years. While further studies are warranted, this patient's clinical course may suggest that radioembolization may be an additional palliative treatment option in these patients.
authors.affiliation: Department of Radiology, Division of Interventional Radiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York.
authors.forename: Ronald S
authors.initials: RS
authors.lastname: Winokur
authors.affiliation: Department of Radiology, Division of Interventional Radiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York.
authors.forename: Adam D
authors.initials: AD
authors.lastname: Talenfeld
authors.affiliation: Division of Nuclear Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York.
authors.forename: P David
authors.initials: PD
authors.lastname: Mozley
authors.affiliation: Department of Radiology, Division of Interventional Radiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, New York. Electronic address: dcm9006@med.cornell.edu.
authors.forename: David C
authors.initials: DC
authors.lastname: Madoff
mesh_terms: D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D008863:Microspheres; D012422:Rupture, Spontaneous; D016896:Treatment Outcome; D015021:Yttrium Radioisotopes / Q000627:therapeutic use*
chemical_list: D015021:Yttrium Radioisotopes
keywords: Hepatocellular carcinoma; Microsphere; Radioembolotherapy; Tumor rupture; Yttrium-90