title: Pediatric Nodular Lymphocyte-predominant Hodgkin Lymphoma: Treatment Recommendations of the GPOH-HD Study Group.
abstract: Nodular lymphocyte-predominant Hodgkin lymphoma (nLPHL) is a very rare disease in childhood and adolescence. In Germany, about 15 newly diagnosed patients present with this disease annually; this number comprises less than 10% of all pediatric Hodgkin lymphoma cases. Since the EuroNet-PHL-LP1 trial for early stage nLPHL patients stopped recruiting in Germany in October 2014, the GPOH-HD writing committee reviewed the literature and decided to deliver treatment recommendations for childhood and adolescent nLPHL patients. These guidelines shall be applicable to young nLPHL patients in European countries that will no longer be able to participate in nLPHL trials for young patients. Therefore, the EuroNet-PHL-nLPHL-registry will be installed to provide quality assured central review of staging and response assessment for registered patients by the Central Review Board of EuroNet-PHL in Halle/Leipzig, Germany.
authors.affiliation: Klinik für Kinder- und Jugendmedizin, Martin-Luther-Universität Halle/ Wittenberg, Halle/ Saale, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Mauz-Körholz
authors.affiliation: Klinik für Kinder- und Jugendmedizin, Martin-Luther-Universität Halle/ Wittenberg, Halle/ Saale, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Lange
authors.affiliation: Institut für Medizinische Informatik, Statistik & Epidemiologie (IMISE), Universität Leipzig, Leipzig, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Hasenclever
authors.affiliation: Clinic for Pediatric Hematology and Oncology, University Hospital Münster, Münster, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Burkhardt
authors.affiliation: Institute for Pathology, University Hospital Schleswig-Holstein, Lübeck, Germany.
authors.forename: A C
authors.initials: AC
authors.lastname: Feller
authors.affiliation: Clinic for Pediatric and Youth Medicine, Helios Hospital Berlin-Buch, Berlin, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Dörffel
authors.affiliation: Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Leipzig, Leipzig, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Kluge
authors.affiliation: Clinic and Policlinic for Radiation Therapy, University Hospital Halle (Saale), Halle (Saale), Germany.
authors.forename: D
authors.initials: D
authors.lastname: Vordermark
authors.affiliation: Klinik für Kinder- und Jugendmedizin, Martin-Luther-Universität Halle/ Wittenberg, Halle/ Saale, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Körholz
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D032921:Consensus; D005060:Europe; D005858:Germany; D019983:Guideline Adherence; D006689:Hodgkin Disease / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D009367:Neoplasm Staging; D011785:Quality Assurance, Health Care