title: Ultrasound-guided high-intensity focused ultrasound (USgHIFU) ablation for the treatment of patients with adenomyosis and prior abdominal surgical scars: A retrospective study.
abstract: OBJECTIVE
  The aim of this paper was to retrospectively compare the therapeutic efficacy and adverse effects of ultrasound-guided high-intensity focused ultrasound (USgHIFU) treatment for adenomyotic patients with or without prior abdominal surgical scars.
  
  
  METHODS
  From January 2011 to March 2014, 534 patients with adenomyosis were referred for HIFU treatment. Among them, 118 patients had prior abdominal surgical scars, 416 patients did not have prior abdominal surgical scars. Contrast-enhanced MRI was used to evaluate the treatment outcomes. All the adverse effects were recorded.
  
  
  RESULTS
  All patients completed USgHIFU treatment. A fractional ablation of 74.8 ± 27.8% was achieved in the group of patients without abdominal scars; the fractional ablation was 75.6 ± 22.3% in the group of patients with prior abdominal surgical scars. No significant difference in fractional ablation between the two groups was observed (p > 0.05). The rate of skin burn in the group of patients with prior abdominal surgical scars was significantly higher than that in the group without abdominal scars (2.5% vs. 0.2%, p < 0.05), but it is still acceptable.
  
  
  CONCLUSIONS
  The prior abdominal surgical scars have no significant influence on the effectiveness of HIFU treatment for adenomyosis. The risk of skin burn is higher in patients with abdominal scars than without, but the incidence rate is still acceptable.
authors.affiliation: a Department of Obstetrics and Gynaecology , Chongqing Haifu Hospital , Chongqing , China .
authors.forename: Yu
authors.initials: Y
authors.lastname: Xiong
authors.affiliation: b State Key Laboratory of Ultrasound Engineering in Medicine, College of Biomedical Engineering, Chongqing Medical University , Chongqing , China .
authors.forename: Yan
authors.initials: Y
authors.lastname: Yue
authors.affiliation: b State Key Laboratory of Ultrasound Engineering in Medicine, College of Biomedical Engineering, Chongqing Medical University , Chongqing , China .
authors.forename: Lian
authors.initials: L
authors.lastname: Shui
authors.affiliation: c Interventional Radiology Unit, European Institute of Oncology , Milan , Italy , and.
authors.forename: Franco
authors.initials: F
authors.lastname: Orsi
authors.affiliation: d Department of Obstetrics and Gynaecology , Suining Central Hospital , Sichuan , China.
authors.forename: Jia
authors.initials: J
authors.lastname: He
authors.affiliation: a Department of Obstetrics and Gynaecology , Chongqing Haifu Hospital , Chongqing , China .|b State Key Laboratory of Ultrasound Engineering in Medicine, College of Biomedical Engineering, Chongqing Medical University , Chongqing , China .
authors.forename: Lian
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000005:Abdomen; D062788:Adenomyosis / Q000628:therapy*; D000328:Adult; D002921:Cicatrix / Q000628:therapy*; D005260:Female; D057086:High-Intensity Focused Ultrasound Ablation / Q000706:statistics & numerical data*; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D014464:Ultrasonic Therapy
keywords: Abdominal surgical scars; adenomyosis; skin burn; ultrasound-guided high-intensity focused ultrasound (USgHIFU)