title: In-hospital clinical outcomes of elderly patients (≥60 years) undergoing primary percutaneous coronary intervention.
abstract: Elderly patients are at high risk of mortality when they present with ST-elevation myocardial infarction (STEMI). However, the clinical outcomes of this sub-group undergoing primary percutaneous coronary intervention (PPCI) have not been well established, despite recent advances in both devices and techniques. In the present retrospective cohort study from a Chinese single center, we assessed the clinical outcomes and predictors of mortality in elderly patients (≥60 years) underwent with PPCI. The primary endpoints were immediate angiographic success and in-hospital procedural success. The secondary endpoints were all-cause death in hospital. Between January 2011 and December 2013, a total of 184 consecutive patients with acute STEMI underwent PPCI were enrolled. 116 (63.04%) patients were in the elderly group. Despite the difference in lesion complexity between groups, the immediate angiographic success rate was similar (93.97% in the elderly group, and 94.12% in the non-elderly group, P=0.966). The procedural success rate were not significantly different between the two groups (90.52% in the elderly group, and 94.12% in the non-elderly group, P=0.389). However, in-hospital mortality was statistically higher in elderly group than in the non-elderly group (8.62% Vs 1.47%, P=0.048). The major causes of death were cardiac shock and malignant arrhythmias (ventricular tachycardia and fibrillation). Our results indicate that PPCI in the elderly is feasible and has a high likelihood of immediate angiographic and procedural success.
authors.affiliation: Department of Cardiology, Affiliated Hospital of Nantong University Nantong 226001, P. R. China.
authors.forename: Ya-Min
authors.initials: YM
authors.lastname: Su
authors.affiliation: Department of Cardiology, Affiliated Hospital of Nantong University Nantong 226001, P. R. China.
authors.forename: Xing-Xing
authors.initials: XX
authors.lastname: Cai
authors.affiliation: Department of Cardiology, Affiliated Hospital of Nantong University Nantong 226001, P. R. China.
authors.forename: Hai-Hua
authors.initials: HH
authors.lastname: Geng
authors.affiliation: Department of Cardiology, Affiliated Hospital of Nantong University Nantong 226001, P. R. China.
authors.forename: Hong-Zhuan
authors.initials: HZ
authors.lastname: Sheng
authors.affiliation: Department of Cardiology, Affiliated Hospital of Nantong University Nantong 226001, P. R. China.
authors.forename: Meng-Kan
authors.initials: MK
authors.lastname: Fan
authors.affiliation: Department of Cardiology, Affiliated Hospital of Nantong University Nantong 226001, P. R. China.
authors.forename: Min
authors.initials: M
authors.lastname: Pan
keywords: Coronary artery disease; ST-elevation myocardial infarction; elderly; primary percutaneous coronary intervention