title: Conserved tegument protein complexes: Essential components in the assembly of herpesviruses.
abstract: One of the structural components of herpesviruses is a protein layer called the tegument. Several of the tegument proteins are highly conserved across the herpesvirus family and serve as a logical focus for defining critical interactions required for viral assembly. A number of studies have helped to elucidate a role for conserved tegument proteins in the process of secondary envelopment during the course of herpesviral assembly. This review highlights how these tegument proteins directly contribute to bridging the nucleocapsid and envelope of virions during secondary envelopment.
authors.affiliation: Centre for Virus Research, Westmead Millennium Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. Electronic address: russell.diefenbach@sydney.edu.au.
authors.forename: Russell J
authors.initials: RJ
authors.lastname: Diefenbach
mesh_terms: D006564:Herpesviridae / Q000502:physiology*; D046911:Macromolecular Substances / Q000378:metabolism; D019251:Nucleocapsid / Q000378:metabolism; D014759:Viral Envelope Proteins / Q000378:metabolism; D015678:Viral Structural Proteins / Q000378:metabolism*; D019065:Virus Assembly
chemical_list: D046911:Macromolecular Substances; D014759:Viral Envelope Proteins; D015678:Viral Structural Proteins
keywords: Assembly; Envelopment; HSV-1; Herpesviridae; Herpesvirus; Tegument