title: The génépi Artemisia species. Ethnopharmacology, cultivation, phytochemistry, and bioactivity.
abstract: Wormwoods (Artemisia species) from the génépi group are, along with Edelweiss, iconic plants of the Alpine region and true symbols of inaccessibility because of their rarity and their habitat, largely limited to moraines of glaciers and rock crevices. Infusions and liqueurs prepared from génépis have always enjoyed a panacea status in folk medicine, especially as thermogenic agents and remedies for fatigue, dyspepsia, and airway infections. In the wake of the successful cultivation of white génépi (Artemisia umbelliformis Lam.) and the expansion of its supply chain, modern studies have evidenced the occurrence of unique constituents, whose chemistry, biological profile, and sensory properties are reviewed along with the ethnopharmacology, botany, cultivation and conservation strategies of their plant sources.
authors.affiliation: Agroscope, Institute for Plant Production Sciences, 1964 Conthey, Switzerland. Electronic address: jose.vouillamoz@agroscope.admin.ch.
authors.forename: José F
authors.initials: JF
authors.lastname: Vouillamoz
authors.affiliation: Agroscope, Institute for Plant Production Sciences, 1964 Conthey, Switzerland.
authors.forename: Christoph
authors.initials: C
authors.lastname: Carlen
authors.affiliation: Dipartimento di Farmacia, Università di Napoli Federico II, Via Montesano 49, 80131 Napoli, Italy.
authors.forename: Orazio
authors.initials: O
authors.lastname: Taglialatela-Scafati
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Pollastro
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy. Electronic address: giovanni.appendino@pharm.uniupo.it.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Appendino
mesh_terms: D019306:Artemisia / Q000737:chemistry* / Q000235:genetics; D003247:Conservation of Natural Resources; D020834:Ethnopharmacology; D005060:Europe; D015394:Molecular Structure; D064209:Phytochemicals / Q000737:chemistry*; D000069600:Plant Breeding
chemical_list: D064209:Phytochemicals
keywords: Artemisia umbelliformis; Bitter receptors; Cultivation; Eupatilin; Génépi; Sesquiterpene lactones