title: A Remarkably Efficient MnFe2 O4 -based Oxidase Nanozyme.
abstract: Nanomaterials-based enzyme mimetics (nanozymes) have attracted considerable interest due to their applications in imaging, diagnostics, and therapeutic treatments. Particularly, metal-oxide nanozymes have been shown to mimic the interesting redox properties and biological activities of metalloenzymes. Here we describe an efficient synthesis of MnFe2 O4 nanomaterials and show how the morphology can be controlled by using a simple co-precipitation method. The nanomaterials prepared by this method exhibit a remarkable oxidase-like activity. Interestingly, the activity is morphology-dependent, with nanooctahedra (NOh) exhibiting a catalytic efficiency of 2.21×10(9)  m(-1)  s(-1) , the highest activity ever reported for a nanozyme.
authors.affiliation: Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, 560012, India.
authors.forename: Amit A
authors.initials: AA
authors.lastname: Vernekar
authors.affiliation: Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, 560012, India.
authors.forename: Tandrila
authors.initials: T
authors.lastname: Das
authors.affiliation: Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, 560012, India.
authors.forename: Sourav
authors.initials: S
authors.lastname: Ghosh
authors.affiliation: Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, 560012, India. mugesh@ipc.iisc.ernet.in.
authors.forename: Govindasamy
authors.identifier: http://orcid.org/0000-0002-5389-5309
authors.initials: G
authors.lastname: Mugesh
mesh_terms: D007501:Iron / Q000737:chemistry / Q000378:metabolism*; D008345:Manganese / Q000737:chemistry / Q000378:metabolism*; D049329:Nanostructures / Q000737:chemistry*; D010088:Oxidoreductases / Q000737:chemistry / Q000378:metabolism*; D010100:Oxygen / Q000737:chemistry / Q000378:metabolism*; D010316:Particle Size; D013499:Surface Properties
chemical_list: D008345:Manganese; D007501:Iron; D010088:Oxidoreductases; D010100:Oxygen
keywords: catalytic efficiency; enzyme mimetics; morphology; nanooctahedra; nanozymes; oxidases