title: Chemical composition of the essential oil of Kaliphora madagascariensis Hook. f.
abstract: Kaliphora madagascariensis is an evergreen shrub or small tree endemic to Madagascar where it is traditionally used for the treatment of persistent cephalalgia by a strong inhalation of its odour. In this work, we analysed for the first time the essential oil obtained from leaves by Gas Chromatography-Mass Spectrometry. The chemical composition was dominated by oxygenated sesquiterpenes (68.1%), with caryophyllene oxide (14.7%) and β-eudesmol (10.7%) as the most abundant constituents. These compounds are endowed with documented healthy effects such as analgesic, anti-inflammatory, neuritogenic, antiepileptic and hypotensive, and its abundance might explain the traditional use of the plant in Madagascar.
authors.affiliation: a Institut Malgache des Recherches Appliquées , Antananarivo , Madagascar.
authors.forename: Rianasoambolanoro
authors.initials: R
authors.lastname: Rakotosaona
authors.affiliation: b Department of Environmental Biology , Sapienza University , Rome , Italy.
authors.forename: Marcello
authors.initials: M
authors.lastname: Nicoletti
authors.affiliation: c School of Pharmacy , University of Camerino , Camerino , Italy.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Papa
authors.affiliation: a Institut Malgache des Recherches Appliquées , Antananarivo , Madagascar.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Randrianarivo
authors.affiliation: a Institut Malgache des Recherches Appliquées , Antananarivo , Madagascar.
authors.forename: Philippe
authors.initials: P
authors.lastname: Rasoanaivo
authors.affiliation: c School of Pharmacy , University of Camerino , Camerino , Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Maggi
mesh_terms: D008401:Gas Chromatography-Mass Spectrometry; D008270:Madagascar; D019684:Magnoliopsida / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry*; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000302:isolation & purification; D045787:Sesquiterpenes, Eudesmane / Q000302:isolation & purification
chemical_list: D009822:Oils, Volatile; D010938:Plant Oils; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; D045787:Sesquiterpenes, Eudesmane; C051082:beta-eudesmol; C515179:caryophyllene oxide
keywords: GC–MS; Kaliphora madagascariensis; caryophyllene oxide; essential oil; β-eudesmol