title: 2'-Methoxyacetophenone: An Efficient Photosensitizer for Cyclobutane Pyrimidine Dimer Formation.
abstract: Stationary and time-resolved experiments show that 2'-methoxyacetophenone (2-M) is an interesting compound for the investigation of triplet states in thymine samples. Time-resolved emission experiments show that the fluorescence lifetime of 2-M is 660 ps. A similar time constant of 680 ps is found in transient IR experiments. The data indicate efficient intersystem crossing (≈97%) from the fluorescent singlet state to the triplet state. The lifetime of the triplet state of 2-M dissolved in D2O at room temperature and ambient oxygen concentration is 400 ns. 2-M has a strong absorption in the UV-A range and can photosensitize the triplet state of a thymidine dinucleotide with light at a wavelength of 320 nm. The experiments show that 2-M is well-suited for time-resolved experiments on the triplet-sensitizing process.
authors.affiliation: Lehrstuhl für BioMolekulare Optik, Fakultät für Physik and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538, München, Germany.
authors.forename: Lizhe
authors.initials: L
authors.lastname: Liu
authors.affiliation: Lehrstuhl für BioMolekulare Optik, Fakultät für Physik and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538, München, Germany.
authors.forename: Bert M
authors.initials: BM
authors.lastname: Pilles
authors.affiliation: Lehrstuhl für BioMolekulare Optik, Fakultät für Physik and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538, München, Germany.
authors.forename: Anne M
authors.initials: AM
authors.lastname: Reiner
authors.affiliation: Lehrstuhl für BioMolekulare Optik, Fakultät für Physik and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538, München, Germany.
authors.forename: Julia
authors.initials: J
authors.lastname: Gontcharov
authors.affiliation: Lehrstuhl für BioMolekulare Optik, Fakultät für Physik and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Oettingenstr. 67, 80538, München, Germany. wolfgang.zinth@physik.uni-muenchen.de.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Zinth
mesh_terms: D000098:Acetophenones; D017666:Deuterium Oxide / Q000737:chemistry; D008027:Light; D017319:Photosensitizing Agents / Q000737:chemistry*; D011740:Pyrimidine Dimers / Q000737:chemistry*; D011789:Quantum Theory; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature
chemical_list: D000098:Acetophenones; D017319:Photosensitizing Agents; D011740:Pyrimidine Dimers; C000611414:2'-methoxyacetophenone; D017666:Deuterium Oxide
keywords: DNA photolesion; photochemistry; photosensitizer; thymine; time-resolved spectroscopy