title: [Use of inflammatory markers for monitoring paediatric asthma].
abstract: The assessment of asthma control takes into account the symptoms, quality of life, lung function, and inflammatory markers. In the last few years, there has been a large increase in the number of publications related to the study of biomarkers in the management of paediatric asthma. Despite the large variety of inflammatory markers described in research studies, only a small group has shown to be useful in monitoring the disease. Induced sputum eosinophils offer the most solid evidence in assessing asthma control. Exhaled breath condensate and urinary leucotrienes could be useful in the future if there is standardisation in their procedures and interpretation of the results. Nitric oxide, basic eosinophil cationic protein, and bronchial biopsy with bronchoalveolar lavage, only appeared to be useful in a reduced group of patients.
authors.affiliation: Pediatra, Broncopulmonar, Departamento de Pediatría, Clínica Las Condes, Santiago, Chile. Electronic address: aevgmd@yahoo.es.
authors.forename: Alberto
authors.initials: A
authors.lastname: Vidal G
mesh_terms: D001249:Asthma / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D015415:Biomarkers / Q000378:metabolism*; D018893:Bronchoalveolar Lavage / Q000379:methods; D002648:Child; D004804:Eosinophils / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D009569:Nitric Oxide / Q000378:metabolism; D011788:Quality of Life; D013183:Sputum
chemical_list: D015415:Biomarkers; D009569:Nitric Oxide
keywords: Asma; Asthma; Biomarcadores; Biomarkers; Pediatrics; Pediatría