title: Vitamin D Levels in Patients With Type 2 Diabetes Mellitus.
abstract: BACKGROUND
  Vitamin D may influence many diseases, including type 2 diabetes mellitus.
  
  
  METHODS
  We studied serum levels of 25-hydroxyvitamin D (25(OH)D) and associated characteristics in type 2 diabetic outpatients with pharmacologic treatment attended in internal medicine offices in a first-level hospital from Extremadura (Southern Spain).
  
  
  RESULTS
  We included a total of 103 patients. Seventy-two patients (69.9%) had serum levels of 25(OH)D lower than 20 ng/mL. There was inverse correlation between serum levels of 25(OH)D and glycosylated hemoglobin (r = -0.74, P = 0.01). In 78 patients without insulin therapy, we found inverse correlation between serum levels of 25(OH)D and fasting serum insulin (r = -0.82, P = 0.001) and Homeostasis Model Assessment-Insulin Resistance (r = -0.51, P < 0.001).
  
  
  CONCLUSIONS
  Vitamin D deficiency is common in type 2 diabetic patients. There are inverse correlations between vitamin D and metabolic control and insulin resistance.
authors.affiliation: From Internal Medicine Service, Hospital Ciudad de Coria, Coria, Cáceres, Spain.
authors.forename: José María
authors.initials: JM
authors.lastname: Calvo-Romero
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Ramiro-Lozano
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood* / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D014807:Vitamin D; C104450:25-hydroxyvitamin D