title: Descemet Membrane Detachment in a Child With Anterior Megalophthalmos Managed Using Intracameral Perflouropropane (C3F8) Gas Injection.
abstract: OBJECTIVE
  To report a case of spontaneous Descemet-membrane detachment in a patient with anterior megalophthalmos managed by intracameral perflouropropane (C3F8) gas instillation.
  
  
  METHODS
  Retrospective case review.
  
  
  RESULTS
  A 12-year-old boy presented with spontaneous corneal edema in the left eye. The anterior segment findings were suggestive of anterior megalophthalmos. Slit-lamp examination of the left eye revealed a detached Descemet membrane superiorly. Anterior segment optical coherence tomography delineated the detached Descemet membrane. Descemetopexy with nonexpansile 14% perflouropropane (C3F8) gas resulted in rapid and complete resolution of corneal edema.
  
  
  CONCLUSIONS
  Patients with anterior megalophthalmos can develop spontaneous detachment of Descemet membrane, which can be effectively managed by intracameral gas instillation.
authors.affiliation: *Cornea and Anterior Segment Services; and †VST Glaucoma Center, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, India.
authors.forename: Sunita
authors.initials: S
authors.lastname: Chaurasia
authors.forename: Muralidhar
authors.initials: M
authors.lastname: Ramappa
authors.forename: Harsha Laxman
authors.initials: HL
authors.lastname: Rao
mesh_terms: D002648:Child; D003315:Cornea / Q000002:abnormalities*; D015715:Corneal Edema / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D003886:Descemet Membrane / Q000473:pathology*; D058450:Endotamponade; D005124:Eye Abnormalities / Q000150:complications*; D005466:Fluorocarbons / Q000008:administration & dosage*; D006801:Humans; D056965:Injections, Intraocular; D008297:Male; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence
chemical_list: D005466:Fluorocarbons; C042852:perflutren