title: A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force.
abstract: OBJECTIVE
  In the coming generation, older adults with bipolar disorder (BD) will increase in absolute numbers as well as proportion of the general population. This is the first report of the International Society for Bipolar Disorder (ISBD) Task Force on Older-Age Bipolar Disorder (OABD).
  
  
  METHODS
  This task force report addresses the unique aspects of OABD including epidemiology and clinical features, neuropathology and biomarkers, physical health, cognition, and care approaches.
  
  
  RESULTS
  The report describes an expert consensus summary on OABD that is intended to advance the care of patients, and shed light on issues of relevance to BD research across the lifespan. Although there is still a dearth of research and health efforts focused on older adults with BD, emerging data have brought some answers, innovative questions, and novel perspectives related to the notion of late onset, medical comorbidity, and the vexing issue of cognitive impairment and decline.
  
  
  CONCLUSIONS
  Improving our understanding of the biological, clinical, and social underpinnings relevant to OABD is an indispensable step in building a complete map of BD across the lifespan.
authors.affiliation: Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH, USA.
authors.forename: Martha
authors.initials: M
authors.lastname: Sajatovic
authors.affiliation: Bipolar Disorder Program, Neurosciences Institute, Favaloro University, Buenos Aires, Argentina.
authors.forename: Sergio A
authors.initials: SA
authors.lastname: Strejilevich
authors.affiliation: Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA.
authors.forename: Ariel G
authors.initials: AG
authors.lastname: Gildengers
authors.affiliation: Department of Old Age Psychiatry, GGZ inGeest, EMGO Institute of Care and Health Research, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Annemiek
authors.initials: A
authors.lastname: Dols
authors.affiliation: Michael E. DeBakey VA Medical Center, Houston, TX, USA.|Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
authors.forename: Rayan K
authors.initials: RK
authors.lastname: Al Jurdi
authors.affiliation: Division of Geriatric Psychiatry, McLean Hospital, Harvard Medical School, Boston, MA, USA.
authors.forename: Brent P
authors.initials: BP
authors.lastname: Forester
authors.affiliation: Psychiatric Centre Copenhagen, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: Lars Vedel
authors.initials: LV
authors.lastname: Kessing
authors.affiliation: Duke University Medical Center, Durham, NC, USA.
authors.forename: John
authors.initials: J
authors.lastname: Beyer
authors.affiliation: Institute of Cognitive Neurology (INECO), Favaloro University, Buenos Aires, Argentina.|Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina.|UDP-INECO Foundation Core on Neuroscience (UIFCoN), Diego Portales University, Santiago, Chile.|National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.|Australian Research Council (ACR) Centre of Excellence in Cognition and its Disorders, Macquarie University, Sydney, NSW, Australia.
authors.forename: Facundo
authors.initials: F
authors.lastname: Manes
authors.affiliation: Department of Psychiatry, University of Toronto, Toronto, ON, Canada.|Geri PARTy Research Group, Jewish General Hospital, Montreal, QC, Canada.
authors.forename: Soham
authors.initials: S
authors.lastname: Rej
authors.affiliation: Federal University of Rio Grande do Sul, Porto Alegre, Brazil.|Department of Pharmacology, Laboratory of Molecular Psychiatry, INCT for Translational Medicine-CNPq, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Adriane R
authors.initials: AR
authors.lastname: Rosa
authors.affiliation: Department of Old Age Psychiatry, GGZ inGeest, EMGO Institute of Care and Health Research, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Sigfried Ntm
authors.initials: SN
authors.lastname: Schouws
authors.affiliation: Department of Psychiatry, Taipei Medical University Hospital, Taipei, Taiwan.|Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
authors.forename: Shang-Ying
authors.initials: SY
authors.lastname: Tsai
authors.affiliation: Weill Cornell Medical College and New York Presbyterian Hospital, White Plains, NY, USA.
authors.forename: Robert C
authors.initials: RC
authors.lastname: Young
authors.affiliation: Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Kenneth I
authors.initials: KI
authors.lastname: Shulman
mesh_terms: D017668:Age of Onset; D000368:Aged; D001714:Bipolar Disorder / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology / Q000523:psychology; D003071:Cognition; D015897:Comorbidity; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D011619:Psychotropic Drugs / Q000627:therapeutic use*
chemical_list: D011619:Psychotropic Drugs
keywords: bipolar disorder; cognition; elderly; geriatric; manic depressive disorder; mood stabilizers