title: An unusual thrombolytic therapy decision in prosthetic valve thrombosis during early pregnancy.
abstract: Pregnancy is among the risk factors for mechanical valve thrombosis, and even though thrombolytic therapy is contraindicated during pregnancy, it may be used in the treatment of this life-threatening complication. This case report describes a pregnant patient, whose echocardiogram showed evident gradient increase on her mechanical prosthetic mitral valve, and who was treated successfully with tissue plasminogen activator for mechanical valve thrombosis.
authors.affiliation: Department of Cardiology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Erkan
authors.initials: E
authors.lastname: Köklü
authors.affiliation: Department of Cardiology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: İsa Öner
authors.initials: İÖ
authors.lastname: Yüksel
authors.affiliation: Department of Cardiology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Zehra
authors.initials: Z
authors.lastname: Erkal
authors.affiliation: Department of Cardiology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Selçuk
authors.initials: S
authors.lastname: Küçükseymen
authors.affiliation: Department of Cardiology, Antalya Training and Research Hospital, Antalya, Turkey.
authors.forename: Şakir
authors.initials: Ş
authors.lastname: Arslan
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000209:etiology; D017548:Echocardiography, Transesophageal; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000473:pathology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011296:Prenatal Diagnosis; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy