title: Validity and reliability analysis of the Chinese parent version of the Autism Spectrum Rating Scale (6-18 years).
abstract: This study aimed to investigate the validity and reliability of the Chinese parent version of the Autism Spectrum Rating Scale (ASRS, 6-18 years) for a general sample of Chinese children. The study involved assessing 1625 community-based subjects aged 6-12 years from four sites (Shanghai, Guangzhou, Changsha, and Harbin city) in China and 211 clinic-based participants aged 6-18 with a confirmed diagnosis of autism spectrum disorders (ASDs). The internal consistency (Cronbach's alpha) ranged from 0.585 to 0.929, and the test-retest reliability (interclass correlations) ranged from 0.542 to 0.749, indicating no significant difference between the two tests at an interval of 2-4 weeks. The construct validity was relatively excellent, and the concurrent validity with the Social Responsiveness Scale (SRS) (Pearson correlations) was 0.732 between the two total scores. Receiver operating characteristics (ROC) analyses showed excellent and comparable discriminant validity of the ASRS with respect to the SRS, with an area under the curve (AUC) of 0.9507 (95% CI: 0.93-0.97) versus 0.9703 (95% CI: 0.96-0.98), respectively. Our data suggested a cutoff ≥60 for the Chinese version of the ASRS, with good accuracy in screening autism symptoms (sensitivity=94.2%, specificity=77%). The Chinese parent version of the ASRS is therefore a reliable and valid tool for screening autistic symptoms in Chinese children in general.
authors.affiliation: No. 399, Wanyuan Road, Minhang District, Division of Neurology, Children's Hospital of Fudan University, Shanghai, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Zhou
authors.affiliation: No. 399, Wanyuan Road, Minhang District, Division of Neurology, Children's Hospital of Fudan University, Shanghai, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Zhang
authors.affiliation: School of Public Health, Harbin Medical University, Harbin, China.
authors.forename: Lijie
authors.initials: L
authors.lastname: Wu
authors.affiliation: Child Development Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Zou
authors.affiliation: Department of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
authors.forename: Xuerong
authors.initials: X
authors.lastname: Luo
authors.affiliation: State Key Laboratory of Medical Genetics, Changsha, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Xia
authors.affiliation: No. 399, Wanyuan Road, Minhang District, Division of Neurology, Children's Hospital of Fudan University, Shanghai, China.
authors.forename: Yimin
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Child Healthcare, Children's Hospital of Fudan University, Shanghai, China.
authors.forename: Xiu
authors.initials: X
authors.lastname: Xu
authors.affiliation: Children's Hospital of Fudan University, Shanghai, China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Ge
authors.affiliation: School of Public Health, Harbin Medical University, Harbin, China.
authors.forename: Caihong
authors.initials: C
authors.lastname: Sun
authors.affiliation: Child Development Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
authors.forename: Hongzhu
authors.initials: H
authors.lastname: Deng
authors.affiliation: Oregon Health & Science University, Portland, OR, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Fombonne
authors.affiliation: Division of Medical Genetics, Department of Pediatrics and Neurobiology, Duke University School of Medicine, USA.
authors.forename: Yong-Hui
authors.initials: YH
authors.lastname: Jiang
authors.affiliation: Department of Clinical Epidemiology, Children's Hospital of Fudan University, Shanghai, China. Electronic address: yanwl@fudan.edu.cn.
authors.forename: Weili
authors.initials: W
authors.lastname: Yan
authors.affiliation: No. 399, Wanyuan Road, Minhang District, Division of Neurology, Children's Hospital of Fudan University, Shanghai, China. Electronic address: yiwang@shmu.edu.cn.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D044466:Asian People / Q000523:psychology*; D000067877:Autism Spectrum Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D010290:Parents / Q000523:psychology*; D011594:Psychometrics; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards*
keywords: Autism; Child; Epidemiology; Scale; Screening; Validation