title: Open Globe Injuries Presenting With Normal or High Intraocular Pressure.
abstract: OBJECTIVE
  To determine the frequency, clinical characteristics, and visual outcomes of patients who present with high or normal intraocular pressure (IOP) and open globe injuries.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  University of Maryland Medical Center, a level 1 trauma center.
  All cases of open globe injury presenting to The University of Maryland Medical Center from July 2005 to January 2014.
  
  
  METHODS
  Demographics, initial physical examination, computed tomography findings, IOP of the affected and unaffected eyes, and follow-up evaluations.
  
  
  METHODS
  (1) IOP 10 mm Hg or greater and (2) visual acuity.
  
  
  RESULTS
  Of 132 eyes presenting with open globe injury, IOP was recorded in 38 (28%). Mean IOP for the affected and unaffected eyes was 14±10.3 mm Hg and 16.6±4.1 mm Hg, respectively. Twenty-three (59.4%) eyes had IOP greater than 10 mm Hg. Six eyes (16.2%) had IOP greater than 21 mm Hg. Using bivariate analysis, IOP greater than 10 mm Hg was associated with posterior open globe injury (P=0.01), posterior hemorrhage (P=0.04), and intraconal retrobulbar hemorrhage (P=0.05). Adjusting for age, sex, and race, IOP greater than 10 mm Hg was associated with the presence of posterior open globe injury on clinical examination (P=0.04). Higher presenting IOP was found to predict light perception or worse vision (P=0.01). Multivariate analysis showed that poor presenting vision was the best predictor of poor final vision (P<0.01).
  
  
  CONCLUSIONS
  High IOP does not exclude open globe injury. It is a frequent finding in patients with open globe injuries and may be associated with posterior injury and poor visual prognosis.
authors.affiliation: Department of Ophthalmology and Visual Sciences (J.A.M., O.S.), University of Maryland, Baltimore, MD; University of Maryland School of Medicine (S.F., H.A.), Baltimore, MD; and Departments of Radiology (U.K.B.) and Epidemiology (N.E.), University of Maryland, Baltimore, MD.
authors.forename: Jordan A
authors.initials: JA
authors.lastname: Margo
authors.forename: Samantha
authors.initials: S
authors.lastname: Feldman
authors.forename: Hampton
authors.initials: H
authors.lastname: Addis
authors.forename: Uttam K
authors.initials: UK
authors.lastname: Bodanapally
authors.forename: Nancy
authors.initials: N
authors.lastname: Ellish
authors.forename: Osamah
authors.initials: O
authors.lastname: Saeedi
mesh_terms: D000328:Adult; D000368:Aged; D057112:Corneal Perforation / Q000175:diagnosis*; D015807:Eye Injuries, Penetrating / Q000175:diagnosis*; D005260:Female; D006470:Hemorrhage / Q000150:complications / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009917:Orbital Fractures; D057972:Posterior Eye Segment / Q000293:injuries*; D011379:Prognosis; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014193:Trauma Centers; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology