title: An Evaluation on the Effect of Health Education and of Low-Dose Statin in Dyslipidemia among Low-Income Rural Uyghur Adults in Far Western China: A Comprehensive Intervention Study.
abstract: OBJECTIVE
  To evaluate the effect of comprehensive intervention by health education and medical intervention to dyslipidemia Uyghur patients in low-income rural areas in Xinjiang, China.
  
  
  METHODS
  A multistaged (prefecture-county-township-village) stratified cluster random sampling method was used to select participants in southern Xinjiang. Twelve villages in Jiangbazi Township in Jiashi County were chosen. These villages were randomly divided into six intervention groups and six control groups, and local Uyghur aged 18 years or older residing in the village for at least 6 months were interviewed for a baseline prevalence study and to select participants for two years of comprehensive intervention including low dose simvastatin and the effects of the interventions were observed.
  
  
  RESULTS
  A total of 655 participants (347 participants in the intervention groups, 308 participants in the control groups) were randomly selected from 12 villages in Jiangbazi Township, follow-up rate is 87.0%. Compared to baseline mean levels of TG and LDL-C were reduced by 1.39 mmol/L (p < 0.01) and 2.12 mmol/L (p < 0.01) respectively and levels of HDL-C increased by1.22 mmol/L (p < 0.01) in the intervention group. Lipids were controlled in 38.61% of the intervention groups vs. 3.57% of the control groups (p < 0.01). Compared with baseline lipid levels, TG, TC, LDL-C and HDL-C was significantly improved, compared with it was in control groups.
  
  
  CONCLUSIONS
  Blood lipid levels of Uygur patients with dyslipidemia can be effectively improved through health education combined with low-dose statin administration. This suggests that national strategies in public health be developed to improve the treatments to low-income rural minorities with dyslipidemia.
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. jiaojiaolong881202@163.com.
authors.forename: Jiaolong
authors.initials: J
authors.lastname: Ma
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. pge888@sina.com.
authors.forename: Shuxia
authors.initials: S
authors.lastname: Guo
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. marulin@126.com.
authors.forename: Rulin
authors.initials: R
authors.lastname: Ma
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. yfyxxzjy@126.com.
authors.forename: Jingyu
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. liujiaming@shzu.edu.cn.
authors.forename: Jiaming
authors.initials: J
authors.lastname: Liu
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. 13399931625@163.com.
authors.forename: Yusong
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. zmberry@foxmail.com.
authors.forename: Mei
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. guoheng@shzu.edu.cn.
authors.forename: Heng
authors.initials: H
authors.lastname: Guo
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. hejia123.shihezi@163.com.
authors.forename: Jia
authors.initials: J
authors.lastname: He
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. erniu19880215@sina.com.
authors.forename: Yizhong
authors.initials: Y
authors.lastname: Yan
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. murat08123@163.com.
authors.forename: Lati
authors.initials: L
authors.lastname: Mu
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. lishugang@ymail.com.
authors.forename: Shugang
authors.initials: S
authors.lastname: Li
authors.affiliation: Key Laboratory of Xinjiang Endemic and Ethnic Diseases, School of Medicine, Shihezi University, Beier Road, Shihezi City, Xinjiang Uyghur Autonomous Region 832000, China. niuqiang1214@163.com.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Niu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D004334:Drug Administration Schedule; D050171:Dyslipidemias / Q000188:drug therapy* / Q000191:economics / Q000208:ethnology; D005260:Female; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D008913:Minority Groups; D010353:Patient Education as Topic / Q000379:methods*; D011203:Poverty; D015995:Prevalence; D012423:Rural Health; D019821:Simvastatin / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000960:Hypolipidemic Agents; D019821:Simvastatin
keywords: Uyghur; comprehensive intervention; dyslipidemia; evaluation; rural