title: The impact of percutaneous coronary intervention of chronic total occlusions on left ventricular function and clinical outcomes.
abstract: A meta-analysis by Hoebers et al. reported that successful chronic total occlusion (CTO) recanalization resulted in an increase in left ventricular (LV) ejection fraction by 4.44% (P<0.01) and a reduction in LV end-diastolic volume by 6.14 mL/m(2) during follow-up as compared with baseline, suggesting beneficial LV remodeling. These findings are important as the myocardium supplied by a CTO frequently has sustained irreversible injury and further support the clinical benefits of CTO interventions.
authors.affiliation: VA North Texas Healthcare System and University of Texas Southwestern Medical Center, Dallas, Texas, USA.
authors.forename: Georgios E
authors.initials: GE
authors.lastname: Christakopoulos
authors.affiliation: VA North Texas Healthcare System and University of Texas Southwestern Medical Center, Dallas, Texas, USA.
authors.forename: Muhammad Nauman J
authors.initials: MN
authors.lastname: Tarar
authors.affiliation: VA North Texas Healthcare System and University of Texas Southwestern Medical Center, Dallas, Texas, USA.
authors.forename: Emmanouil S
authors.initials: ES
authors.lastname: Brilakis
keywords: Percutaneous coronary intervention (PCI); chronic total occlusion (CTO); left ventricle; outcomes