title: Relationship Between Gender, Age, and Weight and the Serum Ionized Calcium Variations in Dog Periodontal Disease Evolution.
abstract: To analyze the relationships between gender, age, weight, and variations in the levels of serum ionized calcium ([iCa(2+)]) during periodontal disease (PD) evolution. In this study, dogs (n = 50) were divided into 5 groups according to the stage of PD: G0 (no PD), G1 (gingivitis), G2 (initial periodontitis), G3 (moderate periodontitis), and G4 (severe periodontitis). Statistically significant correlations were observed between age, [iCa(2+)] levels, and PD stage. Older dogs had lower [iCa(2+)] levels and more advanced PD stages (high positive correlation), and their body weight decreased as PD developed (negative correlation). Lower [iCa(2+)] values were associated with more severe PD.
authors.affiliation: Anjos of Assis Veterinary Medicine Centre (CMVAA), Rua D.ªFrancisca da Azambuja Nº 9 - 9A, Barreiro, Portugal; Faculty of Veterinary Medicine, Department of Clinic, University of Lisbon (FMV/ULisboa), Av. da, Universidade Técnica de Lisboa, Polo Universitário Alto da Ajuda, Lisbon, Portugal; Centre for Interdisciplinary Research in Animal Health (CIISA), FMV/ULisboa, Av. da, Universidade Técnica de Lisboa, Polo Universitário Alto da Ajuda, Lisbon, Portugal; School of Dental Medicine, Superior Institute of Health Sciences Egas Moniz, Caparica, Portugal. Electronic address: miguelcarreira@fmv.ulisboa.pt.
authors.forename: L Miguel
authors.initials: LM
authors.lastname: Carreira
authors.affiliation: Anjos of Assis Veterinary Medicine Centre (CMVAA), Rua D.ªFrancisca da Azambuja Nº 9 - 9A, Barreiro, Portugal.
authors.forename: Daniela
authors.initials: D
authors.lastname: Dias
authors.affiliation: Anjos of Assis Veterinary Medicine Centre (CMVAA), Rua D.ªFrancisca da Azambuja Nº 9 - 9A, Barreiro, Portugal.
authors.forename: Pedro
authors.initials: P
authors.lastname: Azevedo
mesh_terms: D000367:Age Factors; D000818:Animals; D015415:Biomarkers / Q000097:blood; D001835:Body Weight; D002118:Calcium / Q000097:blood*; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005260:Female; D006801:Humans; D008297:Male; D010510:Periodontal Diseases / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D012737:Sex Factors
chemical_list: D015415:Biomarkers; D002118:Calcium
keywords: age; dog; gender; periodontal disease; serum ionized calcium; weight