title: Biomimetic nanoassembly for targeted antigen delivery and enhanced Th1-type immune response.
abstract: A new type of biomimetic nanoassembly for targeted antigen delivery and enhanced Th1-type response is reported for the first time, to combat the major challenges in the treatment of infected cells.
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. jren@ciac.ac.cn xqu@ciac.ac.cn.
authors.forename: Zhenhua
authors.initials: Z
authors.lastname: Li
authors.forename: Kai
authors.initials: K
authors.lastname: Dong
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Enguo
authors.initials: E
authors.lastname: Ju
authors.forename: Zhaowei
authors.initials: Z
authors.lastname: Chen
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D000818:Animals; D032701:Biomimetics; D002460:Cell Line; D016503:Drug Delivery Systems; D007111:Immunity, Cellular; D008070:Lipopolysaccharides / Q000276:immunology*; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry*; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D018417:Th1 Cells; D051197:Toll-Like Receptor 4 / Q000276:immunology
chemical_list: D008070:Lipopolysaccharides; C493487:Tlr4 protein, mouse; D051197:Toll-Like Receptor 4; D012822:Silicon Dioxide