title: Organoantimony(III)-Containing Tungstoarsenates(III): From Controlled Assembly to Biological Activity.
abstract: A family of three sandwich-type, phenylantimony(III)-containing tungstoarsenates(III), [(PhSb(III) ){Na(H2 O)}As(III) 2 W19 O67 (H2 O)](11-) (1), [(PhSb(III) )2 As(III) 2 W19 O67 (H2 O)](10-) (2), and [(PhSb(III) )3 (B-α-As(III) W9 O33 )2 ](12-) (3), have been synthesized by one-pot procedures and isolated as hydrated alkali metal salts, Cs3 K3.5 Na4.5 [(PhSb(III) ){Na(H2 O)}As(III) 2 W19 O67 (H2 O)]⋅41H2 O (CsKNa-1), Cs4.5 K5.5 [(PhSb(III) )2 As(III) 2 W19 O67 (H2 O)]⋅35H2 O (CsK-2), and Cs4.5 Na7.5 [(PhSb(III) )3 (B-α-As(III) W9 O33 )2 ]⋅42H2 O (CsNa-3). The number of incorporated {PhSb(III) } units could be selectively tuned from one to three by careful control of the reaction parameters. The three compounds were characterized in the solid state by single-crystal XRD, IR spectroscopy, and thermogravimetric analysis. The aqueous solution stability of sandwich polyanions 1-3 was also studied by multinuclear ((1) H, (13) C, (183) W) NMR spectroscopy. Effective inhibitory activity against six different kinds of bacteria was identified for all three polyanions, for which the activity increased with the number of incorporated {PhSb(III) } groups.
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University, P.O. Box 750 561, 28725 Bremen (Germany).
authors.forename: Peng
authors.initials: P
authors.lastname: Yang
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University, P.O. Box 750 561, 28725 Bremen (Germany).|Department of Chemistry, Faculty of Sciences, University of Balamand, P.O. Box 100, Tripoli (Lebanon).
authors.forename: Bassem S
authors.initials: BS
authors.lastname: Bassil
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University, P.O. Box 750 561, 28725 Bremen (Germany).
authors.forename: Zhengguo
authors.initials: Z
authors.lastname: Lin
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University, P.O. Box 750 561, 28725 Bremen (Germany).
authors.forename: Ali
authors.initials: A
authors.lastname: Haider
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University, P.O. Box 750 561, 28725 Bremen (Germany).
authors.forename: Gabriela
authors.initials: G
authors.lastname: Alfaro-Espinoza
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University, P.O. Box 750 561, 28725 Bremen (Germany).
authors.forename: Matthias S
authors.initials: MS
authors.lastname: Ullrich
authors.affiliation: Department of Chemistry, Supramolecular Organic and Organometallic Chemistry Centre (SOOMCC), Faculty of Chemistry and Chemical Engineering, Babes-Bolyai University, Arany Janos Str. 11, RO-400028 Cluj-Napoca (Romania).
authors.forename: Cristian
authors.initials: C
authors.lastname: Silvestru
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University, P.O. Box 750 561, 28725 Bremen (Germany). u.kortz@jacobs-university.de.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Kortz
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D000965:Antimony / Q000737:chemistry*; D001149:Arsenates / Q000737:chemistry*; D001686:Biological Phenomena; D009682:Magnetic Resonance Spectroscopy; D008672:Metals, Alkali / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D000071228:Polyelectrolytes; D011108:Polymers / Q000737:chemistry*; D012492:Salts / Q000737:chemistry; D017973:Tungsten Compounds / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000965:Antimony; D001149:Arsenates; D008672:Metals, Alkali; D000071228:Polyelectrolytes; D011108:Polymers; D012492:Salts; D017973:Tungsten Compounds; C039606:tungstoarsenate
keywords: NMR spectroscopy; biological activity; organoantimony; polyoxometalates; sandwich complexes