title: Indications and Outcomes of Osteoporosis and Bone Modulation Therapies.
abstract: Osteoporosis is a disorder of bone strength that leads to an increased risk of fractures. It is most commonly seen in patients aged 50 or older, although it can sometimes occur at a younger age if there are other comorbidities present. The most common cause of osteoporosis by far is menopause, although it also occurs in men, usually with higher morbidity rates than those seen in women. There are many treatment options available, such as anabolics and antiresorptives, with many more currently being developed. However, osteoporosis remains grossly unrecognized and untreated, resulting in a significant strain on the American economy.
authors.affiliation: Division of Endocrinology, Diabetes and Metabolism, Hofstra North Shore-LIJ School of Medicine, 865 Northern Boulevard, Suite 203, Great Neck, NY 11021, USA. Electronic address: sweinerm@nshs.edu.
authors.forename: Stuart
authors.initials: S
authors.lastname: Weinerman
authors.affiliation: Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Hofstra North Shore-LIJ School of Medicine, 865 Northern Boulevard, Suite 203, Great Neck, NY 11021, USA.
authors.forename: Gianina L
authors.initials: GL
authors.lastname: Usera
mesh_terms: D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D005260:Female; D050723:Fractures, Bone / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D015994:Incidence; D008297:Male; D010024:Osteoporosis / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D012307:Risk Factors; D014481:United States / Q000453:epidemiology
chemical_list: D050071:Bone Density Conservation Agents
keywords: Anabolics; Bisphosphonates; Bone mineral density; FRAX; Fracture; Glucocorticoids; Osteoporosis