title: Application of modified antisense oligonucleotides and siRNAs as antiviral drugs.
authors.affiliation: BioNukleo, Department of Bioprocess Engineering, Berlin University of Technology, Berlin, Germany.
authors.forename: Anke
authors.initials: A
authors.lastname: Wagner
authors.affiliation: Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
authors.forename: Claus-Thomas
authors.initials: CT
authors.lastname: Bock
authors.affiliation: Department of Applied Biochemistry, Institute of Biotechnology, Berlin University of Technology, Berlin, Germany.
authors.forename: Henry
authors.initials: H
authors.lastname: Fechner
authors.affiliation: Department of Applied Biochemistry, Institute of Biotechnology, Berlin University of Technology, Berlin, Germany.
authors.forename: Jens
authors.initials: J
authors.lastname: Kurreck
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D055808:Drug Discovery / Q000379:methods; D006801:Humans; D016376:Oligonucleotides, Antisense / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D034741:RNA, Small Interfering / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D000067492:RNAi Therapeutics / Q000379:methods*; D014777:Virus Diseases / Q000188:drug therapy / Q000235:genetics / Q000628:therapy*; D014780:Viruses / Q000187:drug effects* / Q000235:genetics
chemical_list: D000998:Antiviral Agents; D016376:Oligonucleotides, Antisense; D034741:RNA, Small Interfering
keywords: antisense oligonucleotide; antiviral therapy; delivery system; modified nucleotides; post-transcriptional gene silencing; siRNAs