title: Top value platform chemicals: bio-based production of organic acids.
abstract: Driven by the quest for sustainability, recent years have seen a tremendous progress in bio-based production routes from renewable raw materials to commercial goods. Particularly, the production of organic acids has crystallized as a competitive and fast-evolving field, related to the broad applicability of organic acids for direct use, as polymer building blocks, and as commodity chemicals. Here, we review recent advances in metabolic engineering and industrial market scenarios with focus on organic acids as top value products from biomass, accessible through fermentation and biotransformation.
authors.affiliation: Institute of Systems Biotechnology, Universität des Saarlandes, Germany.
authors.forename: Judith
authors.initials: J
authors.lastname: Becker
authors.affiliation: Institute of Systems Biotechnology, Universität des Saarlandes, Germany.
authors.forename: Anna
authors.initials: A
authors.lastname: Lange
authors.affiliation: Institute of Systems Biotechnology, Universität des Saarlandes, Germany.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Fabarius
authors.affiliation: Institute of Systems Biotechnology, Universität des Saarlandes, Germany. Electronic address: christoph.wittmann@uni-saarland.de.
authors.forename: Christoph
authors.initials: C
authors.lastname: Wittmann
mesh_terms: D000818:Animals; D018533:Biomass; D001711:Biotransformation; D005285:Fermentation; D006801:Humans; D060847:Metabolic Engineering / Q000379:methods*; D009930:Organic Chemicals / Q000378:metabolism*; D011108:Polymers / Q000378:metabolism
chemical_list: D009930:Organic Chemicals; D011108:Polymers