title: Prevalence of congenital heart disease in 76,301 mixed-breed dogs and 57,025 mixed-breed cats.
abstract: OBJECTIVE
  Assess the prevalence of congenital heart disease (CHD) in a large population of mixed-breed dogs and cats.
  
  
  METHODS
  76,301 mixed-breed dogs and 57,025 mixed-breed cats.
  
  
  METHODS
  Retrospective review of records and examinations based on specified diagnostic criteria.
  
  
  RESULTS
  Among mixed-breed dogs, the prevalence of CHD was 0.13% (51.4% female) and of innocent murmurs was 0.10% (53.0% male). Pulmonic stenosis was the most common defect followed by patent ductus arteriosus, aortic stenosis, and ventricular septal defect. Among mixed-breed cats, prevalence of CHD was 0.14% (55.2% male) and of innocent murmurs was 0.16% (54.4% male). When the 25 cats with dynamic left or right ventricular outflow obstruction were counted with cases of innocent murmurs, the overall prevalence was 0.2%. Ventricular septal defects were the most common feline CHD followed closely by aortic stenosis and hypertrophic obstructive cardiomyopathy. There was no overall sex predilection for CHD in mixed-breed cats or dogs, and no significant difference in CHD prevalence between cats or dogs. Among dogs, subvalvular aortic stenosis and mitral valve dysplasia had a male predisposition while patent ductus arteriosus had a female predisposition. Among cats, valvular pulmonic stenosis, subvalvular and valvular aortic stenosis, and ventricular septal defects had a male predisposition while pulmonary artery stenosis had a female predisposition.
  
  
  CONCLUSIONS
  The prevalence of CHD in a mixed-breed dogs and cats is lower than for prior studies, perhaps due to the lack of purebreds in the study population or actual changes in disease prevalence.
authors.affiliation: Oradell Animal Hospital, 580 Winters Ave., Paramus, NJ 07652, USA. Electronic address: dpsdvm@optonline.net.
authors.forename: Donald P
authors.initials: DP
authors.lastname: Schrope
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000151:congenital*; D002415:Cats; D004283:Dog Diseases / Q000151:congenital*; D004285:Dogs; D005260:Female; D006330:Heart Defects, Congenital / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies
keywords: Canine; Cardiac; Congenital; Feline; Innocent murmur