title: Immune Reconstitution Inflammatory Syndrome Secondary to Mycobacterium kansasii Infection in a Kidney Transplant Recipient.
abstract: Nontuberculous mycobacteria (NTM) infection is a challenging diagnosis for clinicians in solid organ transplantation. Immune reconstitution inflammatory syndrome (IRIS) is so far unreported in this context. We report here the case of a renal transplant recipient who developed Mycobacterium kansasii-associated lymphadenitis complicated by IRIS while undergoing reduction of his immunosuppressive therapy. For IRIS, the patient required low-dose steroids and an increase in global immunosuppression, in association with NTM antibiotherapy.
authors.affiliation: Service de Néphrologie, CHU Hôpitaux de Rouen, Rouen, France.
authors.forename: M
authors.initials: M
authors.lastname: Lemoine
authors.affiliation: Service de Néphrologie, CHU Hôpitaux de Rouen, Rouen, France.
authors.forename: C
authors.initials: C
authors.lastname: Laurent
authors.affiliation: Service de Néphrologie, CHU Hôpitaux de Rouen, Rouen, France.
authors.forename: M
authors.initials: M
authors.lastname: Hanoy
authors.affiliation: Service de Maladies Infectieuses et Tropicales, CHU Hôpitaux de Rouen, Rouen, France.
authors.forename: J
authors.initials: J
authors.lastname: Leporrier
authors.affiliation: Service d'Anatomie et Cytologie Pathologiques, CHU Hôpitaux de Rouen, Rouen, France.
authors.forename: A
authors.initials: A
authors.lastname: François
authors.affiliation: Service de Néphrologie, CHU Hôpitaux de Rouen, Rouen, France.
authors.forename: D
authors.initials: D
authors.lastname: Guerrot
authors.affiliation: Service de Néphrologie, CHU Hôpitaux de Rouen, Rouen, France.
authors.forename: M
authors.initials: M
authors.lastname: Godin
authors.affiliation: Service de Néphrologie, CHU Hôpitaux de Rouen, Rouen, France.
authors.forename: D
authors.initials: D
authors.lastname: Bertrand
mesh_terms: D000328:Adult; D005919:Glomerular Filtration Rate; D006085:Graft Survival; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000175:diagnosis / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000382:microbiology* / Q000601:surgery; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000382:microbiology; D019909:Mycobacterium kansasii / Q000472:pathogenicity*; D011183:Postoperative Complications; D011379:Prognosis; D012307:Risk Factors; D066027:Transplant Recipients
keywords: antibiotic: antibacterial; clinical research / practice; complication: infectious; immunosuppressive regimens; infection; infectious disease; kidney (allograft) function / dysfunction; kidney transplantation / nephrology; mycobacterial: nontuberculous