title: Fatal tracheal aspergillosis during rituximab combined chemotherapy for diffuse large B-cell lymphoma that developed after lung transplantation.
abstract: Invasive tracheal aspergillosis (ITA) is an infection that is unique to patients who have undergone lung transplantation (LT). Although the activity of this disease often appears on imaging, we encountered a case of ITA that became exacerbated, despite few computed tomography (CT) findings, during rituximab combined chemotherapy for diffuse large B-cell lymphoma. ITA developed during immunosuppressive therapy after LT. Because CT findings may show false-negative results, bronchoscopy is recommended for such cases.
authors.affiliation: Department of Hematology, Endocrinology and Metabolism, Faculty of Medicine, Niigata University, Niigata, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kawamoto
authors.affiliation: Division of Stem Cell Transplantation, Niigata University Medical and Dental Hospital, Niigata, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shibasaki
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Faculty of Medicine, Niigata University, Niigata, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.affiliation: Department of Hematology, Endocrinology and Metabolism, Faculty of Medicine, Niigata University, Niigata, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nemoto
authors.affiliation: Department of Hematology, Endocrinology and Metabolism, Faculty of Medicine, Niigata University, Niigata, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Takizawa
authors.affiliation: Department of Hematology, Endocrinology and Metabolism, Faculty of Medicine, Niigata University, Niigata, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Narita
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Faculty of Medicine, Niigata University, Niigata, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tsuchida
authors.affiliation: Department of Hematology, Endocrinology and Metabolism, Faculty of Medicine, Niigata University, Niigata, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Sone
authors.affiliation: Division of Stem Cell Transplantation, Niigata University Medical and Dental Hospital, Niigata, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Masuko
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001228:Aspergillosis / Q000209:etiology / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D016040:Lung Transplantation / Q000009:adverse effects; D016393:Lymphoma, B-Cell / Q000188:drug therapy*; D008297:Male; D000069283:Rituximab / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D014133:Tracheal Diseases / Q000382:microbiology* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents; D000069283:Rituximab
keywords: bronchoscopy; chemotherapy; invasive tracheal aspergillosis; lung transplantation