title: Cucurbit[8]uril as nanocontainer in a polyelectrolyte multilayer film: a quantitative and kinetic study of guest uptake.
abstract: The host-guest chemistry of cucurbit[8]uril (CB[8]) and the layer-by-layer self-assembly technique are combined to obtain a molecular imprinted polyelectrolyte multilayer film for the recognition and binding of a guest molecule. Cucurbit[8]uril as a ready-made binding site is first associated with a polyelectrolyte and then assembled into a polyelectrolyte multilayer film via layer-by-layer deposition. A cationic guest is subsequently included into the nanocontainer due to specific host-guest interactions. The quantitative analysis of both CB[8] and the included guest molecule in dependence of the surface charge of the multilayer film identifies a high nanocontainer density as well as good to excellent binding efficiencies, therefore yielding a promising imprinted nanomaterial with potential applications in filtration or sensor technology. The investigation of the guest molecule uptake kinetics reveals two processes on different time scales, respectively, which are again related to the charge of the multilayer film surface. The combination of the results obtained from both ultraviolet spectroscopy and dissipative quartz crystal microbalance enables us to describe a full picture of several simultaneous processes initiated by the guest molecule.
authors.affiliation: Institute of Physical Chemistry, University of Muenster , Corrensstrasse 28/30, 48149 Münster, Germany.
authors.forename: Henning
authors.initials: H
authors.lastname: Nicolas
authors.affiliation: Key Laboratory of Organic Optoelectronics & Molecular Engineering, Department of Chemistry, Tsinghua University , Beijing 100084, P. R. China.
authors.forename: Bin
authors.initials: B
authors.lastname: Yuan
authors.affiliation: Key Laboratory of Organic Optoelectronics & Molecular Engineering, Department of Chemistry, Tsinghua University , Beijing 100084, P. R. China.
authors.forename: Jiawei
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Organic Optoelectronics & Molecular Engineering, Department of Chemistry, Tsinghua University , Beijing 100084, P. R. China.
authors.forename: Xi
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Institute of Physical Chemistry, University of Muenster , Corrensstrasse 28/30, 48149 Münster, Germany.
authors.forename: Monika
authors.initials: M
authors.lastname: Schönhoff