title: Distribution of the Endocannabinoid System in the Central Nervous System.
abstract: The endocannabinoid system consists of endogenous cannabinoids (endocannabinoids), the enzymes that synthesize and degrade endocannabinoids, and the receptors that transduce the effects of endocannabinoids. Much of what we know about the function of endocannabinoids comes from studies that combine localization of endocannabinoid system components with physiological or behavioral approaches. This review will focus on the localization of the best-known components of the endocannabinoid system for which the strongest anatomical evidence exists.
authors.affiliation: Department of Psychology, National Cheng Kung University, Tainan, 70101, Taiwan. shujunghu@gmail.com.
authors.forename: Sherry Shu-Jung
authors.initials: SS
authors.lastname: Hu
authors.affiliation: Department of Psychological and Brain Sciences, Indiana University, 47405, Bloomington, IN, USA. kmackie@indiana.edu.|Gill Center for Biomolecular Science, Indiana University, 47405, Bloomington, IN, USA. kmackie@indiana.edu.
authors.forename: Ken
authors.initials: K
authors.lastname: Mackie
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000166:cytology / Q000201:enzymology / Q000378:metabolism*; D063388:Endocannabinoids / Q000096:biosynthesis / Q000378:metabolism*; D006801:Humans; D009474:Neurons / Q000201:enzymology / Q000378:metabolism*; D043884:Receptor, Cannabinoid, CB1 / Q000378:metabolism*; D043885:Receptor, Cannabinoid, CB2 / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D063388:Endocannabinoids; D043884:Receptor, Cannabinoid, CB1; D043885:Receptor, Cannabinoid, CB2
keywords: CB1 cannabinoid receptor; Immunocytochemistry; In situ hybridization