title: A Comparison Between Postoperative Nausea and Vomiting in General Anesthesia With Isoflurane-Remifentanil or Isoflurane in Cholecystectomy Laparoscopic Patients.
abstract: OBJECTIVE
  The purpose of the study was to compare postoperative nausea and vomiting (PONV) between laparoscopic cholecystectomy patients under general anesthesia with isoflurane and remifentanil-isoflurane.
  
  
  METHODS
  An observational study was used.
  
  
  METHODS
  This observational study was performed on 102 patients who were candidates for laparoscopic cholecystectomy under anesthesia with isoflurane or remifentanil-isoflurane. The patients were evaluated for PONV in the PACU and 3 and 6 hours after the operation. Data were analyzed with descriptive and analytical statistics.
  
  
  RESULTS
  At the time of recovery, the incidence of nausea and vomiting was less in patients under general anesthesia with isoflurane when compared to general anesthesia with remifentanil-isoflurane (P < .04). Nausea and vomiting was also less in the isoflurane group (2%) versus the remifentanil-isoflurane group (9%) at 3 and 6 hours after surgery, but the difference was not significant.
  
  
  CONCLUSIONS
  The incidence of PONV in cholecystectomy laparoscopic patients under combined remifentanil with isoflurane anesthesia was relatively low, and it was a bit less in patients under isoflurane anesthesia alone.
authors.forename: Masumeh
authors.initials: M
authors.lastname: Shahnazdust
authors.forename: Atefeh
authors.initials: A
authors.lastname: Ghanbari
authors.forename: Ramin
authors.initials: R
authors.lastname: Noori
authors.forename: Malahat
authors.initials: M
authors.lastname: Khalili
mesh_terms: D000768:Anesthesia, General / Q000009:adverse effects*; D017081:Cholecystectomy, Laparoscopic; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage*; D010880:Piperidines / Q000008:administration & dosage*; D020250:Postoperative Nausea and Vomiting; D000077208:Remifentanil
chemical_list: D010880:Piperidines; D007530:Isoflurane; D000077208:Remifentanil
keywords: PONV; anesthesia; isoflurane; laparoscopic cholecystectomy; remifentanil; research