title: Selective Binding of DNA Origami on Biomimetic Lipid Patches.
abstract: Arrays of biomimetic lipid patches for studying the binding of DNA origami structures can be tailored in size, shape, and composition with the aid of lipid-dip pen nanolithography. This approach allows for analysis of the effects of lipid composition with high throughput which could be applied for the targeted presentation of functional DNA origami structures on surfaces.
authors.affiliation: Institute of Nanotechnology (INT) and Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), 76128, Karlsruhe, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Hirtz
authors.affiliation: Institute for Biological Interfaces (IBG 1), Karlsruhe Institute of Technology (KIT), 76128, Karlsruhe, Germany.
authors.forename: Josipa
authors.initials: J
authors.lastname: Brglez
authors.affiliation: Institute of Nanotechnology (INT) and Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), 76128, Karlsruhe, Germany.|Physical Institute and Center for Nanotechnology (CeNTech), Westfälische Wilhelms-Universität, 48149, Münster, Germany.
authors.forename: Harald
authors.initials: H
authors.lastname: Fuchs
authors.affiliation: Institute for Biological Interfaces (IBG 1), Karlsruhe Institute of Technology (KIT), 76128, Karlsruhe, Germany.
authors.forename: Christof M
authors.initials: CM
authors.lastname: Niemeyer
mesh_terms: D000268:Adhesiveness; D001665:Binding Sites; D040761:Biomimetic Materials / Q000737:chemistry*; D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure*; D008051:Lipid Bilayers / Q000737:chemistry*; D008422:Materials Testing / Q000379:methods; D046228:Microarray Analysis / Q000379:methods*; D054802:Molecular Imprinting / Q000379:methods*; D009690:Nucleic Acid Conformation; D010713:Phosphatidylcholines / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D004247:DNA; C017251:1,2-oleoylphosphatidylcholine
keywords: DNA origami; biomimetic membranes; dip-pen nanolithography; phospholipids; supported lipid bilayer membranes