title: Fontan Liver Disease: Review of an Emerging Epidemic and Management Options.
abstract: Adults with complex congenital heart disease that resulted in a Fontan procedure frequently experience late cardiac failure. Increasingly, liver disease is recognized as an important complication of single-ventricle anatomy and Fontan physiology; however, there is no consensus regarding liver evaluation in this population. Here, we review what is known about liver disease in this unique group and propose screening and prevention measures. We also review controversial treatment areas including assist devices and transplantation, with a review of outcomes in isolated heart and combined heart-liver transplant.
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Medicine, Ohio State University, Columbus, OH, USA. elisa.bradley@osumc.edu.|Division Cardiovascular Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA. elisa.bradley@osumc.edu.
authors.forename: Elisa
authors.initials: E
authors.lastname: Bradley
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Medicine, Ohio State University, Columbus, OH, USA.|Division Cardiovascular Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Hendrickson
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Medicine, Ohio State University, Columbus, OH, USA.|Division Cardiovascular Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.
authors.forename: Curt
authors.initials: C
authors.lastname: Daniels
keywords: Cirrhosis; Fontan; Liver disease; Single ventricle