title: SnapShot: CRISPR-RNA-guided adaptive immune systems.
abstract: Bacteria and archaea have evolved sophisticated adaptive immune systems that reply on CRISPR loci and a diverse cassette of Cas genes that are classified into three main types and at least eleven subtypes. All CRISPR-Cas immune systems operate through three main stages: acquisition, biogenesis, and interference. This SnapShot summarizes our current knowledge of these fascinating immune systems.
authors.affiliation: Montana State University, Department of Microbiology and Immunology, Bozeman, MT 59715, USA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Carter
authors.affiliation: Montana State University, Department of Microbiology and Immunology, Bozeman, MT 59715, USA.
authors.forename: Blake
authors.initials: B
authors.lastname: Wiedenheft
mesh_terms: D001105:Archaea / Q000235:genetics / Q000276:immunology*; D001419:Bacteria / Q000235:genetics / Q000276:immunology*; D064113:CRISPR-Cas Systems; D064112:Clustered Regularly Interspaced Short Palindromic Repeats; D034622:RNA Interference; D000094704:RNA, Guide, CRISPR-Cas Systems / Q000235:genetics*
chemical_list: D000094704:RNA, Guide, CRISPR-Cas Systems