title: Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution.
abstract: An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed.
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, China. hongxiao86@126.com.|College of Environment and Chemical Engineering, Nanchang Hangkong University, Nanchang 330063, China. hongxiao86@126.com.
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Hong
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, China. z1121@126.com.
authors.forename: Yu-Qiang
authors.initials: YQ
authors.lastname: Zhou
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, China. baicuibing@126.com.
authors.forename: Cui-Bing
authors.initials: CB
authors.lastname: Bai
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, China. nxwang@mail.ipc.ac.cn.
authors.forename: Nai-Xing
authors.initials: NX
authors.lastname: Wang
authors.affiliation: Department of Chemistry, William Paterson University of New Jersey, 300 Pompton Road, Wayne, NJ 07470, USA. xingy@wpunj.edu.
authors.forename: Yalan
authors.initials: Y
authors.lastname: Xing
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, China. zhjp271@163.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, China. wangyanjing33@hotmail.com.
authors.forename: Yan-Jing
authors.initials: YJ
authors.lastname: Wang
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, China. hxlxw@sina.cn.
authors.forename: Xing-Wang
authors.initials: XW
authors.lastname: Lan
authors.affiliation: College of Environment and Chemical Engineering, Nanchang Hangkong University, Nanchang 330063, China. yihenim@163.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Xie
authors.affiliation: Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100080, China. yihenim@163.com.
authors.forename: Yi-He
authors.initials: YH
authors.lastname: Li
mesh_terms: D007700:Kinetics; D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D010080:Oxazoles
keywords: 1,3-oxazolidine; asymmetric synthesis; kinetic resolution; multi-component reaction; synthetic methods