title: Flow-Diverter Stents for the Treatment of Saccular Middle Cerebral Artery Bifurcation Aneurysms.
abstract: OBJECTIVE
  The flow-diverter stent has been proved a feasible, safe, and efficient technique, particularly for the treatment of large and broad-neck carotid siphon aneurysms. Wide-neck bifurcation aneurysms remain, in some cases, a challenge for neurointerventionalists. We report the outcomes of the treatment of saccular middle cerebral artery bifurcation aneurysms with flow diversion in our institution.
  
  
  METHODS
  From the institution data base, all saccular, nondissecting MCA bifurcation aneurysms, treated with flow-diverter stents, were retrospectively reviewed. Technical issues, immediate posttreatment and follow-up angiographic findings, and clinical outcomes were assessed.
  
  
  RESULTS
  Fourteen patients with 15 aneurysms were included in the study. Ischemic complications, as confirmed by MR imaging, occurred in 6 patients (43%). Procedure-related morbidity and mortality at last follow-up were 21% and 0%, respectively. Angiographic follow-up was available for 13 aneurysms, with a mean follow-up of 16 months. Complete occlusion was obtained for 8 aneurysms (62%).
  
  
  CONCLUSIONS
  Compared with other available therapeutic options, the flow-diverter stent does not appear to be a suitable solution for the treatment of saccular MCA bifurcation aneurysms.
authors.affiliation: From the Department of Interventional Neuroradiology (J.C., H.N., C.M., H.A.K., L.I., J.M., L.S.), Neuro Brain Vascular Center, Hôpital Bicêtre, APHP, Paris Sud Université, France Jildaz.caroff@bjn.aphp.fr.
authors.forename: J
authors.identifier: http://orcid.org/0000-0002-0029-1835
authors.initials: J
authors.lastname: Caroff
authors.affiliation: From the Department of Interventional Neuroradiology (J.C., H.N., C.M., H.A.K., L.I., J.M., L.S.), Neuro Brain Vascular Center, Hôpital Bicêtre, APHP, Paris Sud Université, France Department of Neurosurgery (H.N.), Saitama University, Saitama, Japan.
authors.forename: H
authors.identifier: http://orcid.org/0000-0003-3472-7702
authors.initials: H
authors.lastname: Neki
authors.affiliation: From the Department of Interventional Neuroradiology (J.C., H.N., C.M., H.A.K., L.I., J.M., L.S.), Neuro Brain Vascular Center, Hôpital Bicêtre, APHP, Paris Sud Université, France Department of Neurosurgery (C.M.), University of Medicine and Pharmacy "Victor Babes," Timisoara, Romania.
authors.forename: C
authors.identifier: http://orcid.org/0000-0002-8260-8284
authors.initials: C
authors.lastname: Mihalea
authors.affiliation: Department of Bioimaging and Radiological Sciences (F.D.), Policlinico "A. Gemelli," Rome, Italy.
authors.forename: F
authors.identifier: http://orcid.org/0000-0003-0184-9682
authors.initials: F
authors.lastname: D'Argento
authors.affiliation: From the Department of Interventional Neuroradiology (J.C., H.N., C.M., H.A.K., L.I., J.M., L.S.), Neuro Brain Vascular Center, Hôpital Bicêtre, APHP, Paris Sud Université, France Department of Neuropsychiatry (H.A.K.), Tanta University Hospital, Tanta, Egypt.
authors.forename: H
authors.identifier: http://orcid.org/0000-0003-2611-5482
authors.initials: H
authors.lastname: Abdel Khalek
authors.affiliation: From the Department of Interventional Neuroradiology (J.C., H.N., C.M., H.A.K., L.I., J.M., L.S.), Neuro Brain Vascular Center, Hôpital Bicêtre, APHP, Paris Sud Université, France.
authors.forename: L
authors.identifier: http://orcid.org/0000-0002-6739-3692
authors.initials: L
authors.lastname: Ikka
authors.affiliation: From the Department of Interventional Neuroradiology (J.C., H.N., C.M., H.A.K., L.I., J.M., L.S.), Neuro Brain Vascular Center, Hôpital Bicêtre, APHP, Paris Sud Université, France.
authors.forename: J
authors.identifier: http://orcid.org/0000-0002-2086-2973
authors.initials: J
authors.lastname: Moret
authors.affiliation: From the Department of Interventional Neuroradiology (J.C., H.N., C.M., H.A.K., L.I., J.M., L.S.), Neuro Brain Vascular Center, Hôpital Bicêtre, APHP, Paris Sud Université, France.
authors.forename: L
authors.identifier: http://orcid.org/0000-0002-6748-8528
authors.initials: L
authors.lastname: Spelle
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents / Q000009:adverse effects; D016896:Treatment Outcome