title: The Presence of New MRI Lesions and Cognitive Decline After Cardiac Surgery: A Systematic Review.
abstract: Patients are commonly reported to experience postoperative cognitive decline (POCD) and new ischemic lesions following surgery, which many researchers have hypothesised to result from emboli entering the cerebral circulation during surgery. Modern magnetic resonance imaging techniques have enabled clear and accurate identification of ischemic lesions. However, difficulties in assessing subtle changes in cognitive impairment clinically remain. The purpose of this systematic review is to discuss the literature that has investigated cognitive outcome in relation to new ischaemic brain lesions after cardiac surgery.
authors.affiliation: Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.|Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, United Kingdom.
authors.forename: Nikil
authors.initials: N
authors.lastname: Patel
authors.affiliation: Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.|University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
authors.forename: Jatinder S
authors.initials: JS
authors.lastname: Minhas
authors.affiliation: Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.|Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, United Kingdom.|Department of Medical Physics, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
authors.forename: Emma M L
authors.initials: EM
authors.lastname: Chung
mesh_terms: D002545:Brain Ischemia / Q000175:diagnosis* / Q000209:etiology; D006348:Cardiac Surgical Procedures; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000209:etiology