title: Evaluation of food products fortified with oyster shell for the prevention and treatment of osteoporosis.
abstract: Production and evaluation of different diet formulas fortified with oyster shell for the prevention and treatment of osteoporosis. Eighty-eight female albino rats were recruited and divided into 11 groups (8 rats each). Group 1 represented negative control while the remaining groups were ovariectomized. Group 2 acted as positive control. Groups 3-5 were fed on basal diet. Groups 6-8 were fed on lentil soup while groups 9-11 were fed on vegetable soup. Group 4, 7, 10 were fed on diets fortified with oyster shell. Groups 5, 8 and 11 were fed on diet formulas fortified with calcium citrate. All calcium fortified diet formulas, especially lentil soup, have minimized risk factors associated with osteoporosis as indicated from the significant increase in tibial weight, total protein, total calcium and phosphorus with noticeable reduction in ALP activity compared to positive group. Maximum recovery was observed for diet fortified with oyster shell. These data suggest that food products fortified with oyster shell as natural and inexpensive source could be beneficial for the prevention and treatment of osteoporosis.
authors.affiliation: Department of Medicinal Food, National Organization for Drug Control and Research (NODCAR), Giza, Egypt.
authors.forename: S A
authors.initials: SA
authors.lastname: Ahmed
authors.affiliation: Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Ahram Canadian University (ACU), 6th of October, Giza Egypt ; Biochemistry and Molecular Biology Department, Faculty of Pharmacy, The British University in Egypt (BUE), P.O. Box 259, Cairo, 11728 Egypt.
authors.forename: Abdullah A Y
authors.initials: AA
authors.lastname: Gibriel
authors.affiliation: Department of Medicinal Food, National Organization for Drug Control and Research (NODCAR), Giza, Egypt.
authors.forename: A K
authors.initials: AK
authors.lastname: Abdellatif
authors.affiliation: Food Science and Technology Department, Faculty of Agriculture, Ain-Shams University, Shoubra El-Kheima, Cairo, Egypt.
authors.forename: H M
authors.initials: HM
authors.lastname: Ebied
keywords: ALP; Calcium; Nutraceuticals; Osteoporosis; Oyster Shell