title: Examining cognitive emotion regulation in frontal lobe patients: The mediating role of response inhibition.
abstract: BACKGROUND
  Previous investigations have demonstrated the relationship between inhibitory deficits and maladaptive emotion regulation. Although several neuropsychological studies show that frontal lobe damage can lead to extreme inhibition impairments, there have been no investigations regarding the influence of frontal lobe damage and related inhibition impairments on the use of maladaptive strategies.
  
  
  OBJECTIVE
  The goal of the current study was to examine the impact of executive functions impairments due to frontal lobe damage on cognitive emotion regulation.
  
  
  METHODS
  Fifteen patients with frontal lobe damage were compared to twenty-two healthy controls on their reported use of maladaptive strategies. The effect of behavioral inhibition deficits among the frontal lobe damage group was examined.
  
  
  RESULTS
  Patients reflected a heightened use of maladaptive strategies compared to healthy controls, significantly mediated by Go/NoGo task errors, which are an indicator for response inhibition deficits.
  
  
  CONCLUSIONS
  Results suggest that a heightened use of maladaptive strategies by patients relies to a strong extent on their impaired impulse control, highlighting the complex interplay between executive functions and emotional regulation.
authors.affiliation: Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Heidelberg, Germany.
authors.forename: Rosalux
authors.initials: R
authors.lastname: Falquez
authors.affiliation: Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Heidelberg, Germany.|Central Institute of Mental Health, Mannheim, Germany.
authors.forename: Ramona
authors.initials: R
authors.lastname: Dinu-Biringer
authors.affiliation: Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Heidelberg, Germany.
authors.forename: Malte
authors.initials: M
authors.lastname: Stopsack
authors.affiliation: Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Heidelberg, Germany.
authors.forename: Elisabeth A
authors.initials: EA
authors.lastname: Arens
authors.affiliation: Neuro-oncology Department, University Hospital, Heidelberg, Germany.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Wick
authors.affiliation: Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Heidelberg, Germany.
authors.forename: Sven
authors.initials: S
authors.lastname: Barnow
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003071:Cognition; D004644:Emotions; D056344:Executive Function; D005260:Female; D057180:Frontotemporal Dementia / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D006801:Humans; D007175:Impulsive Behavior; D007266:Inhibition, Psychological; D008297:Male; D008875:Middle Aged
keywords: Frontal lobe lesion; emotion regulation; maladaptive strategies; response inhibition