title: [OPTIMIZATION OF EARLY DIAGNOSIS OF ACUTE KIDNEY INJURY IN NEWBORNS IN CRITICAL CONDITION].
abstract: Current diagnosis of acute kidney injury (AKI) is one of the most pressing problems in the newborn in critical condition.
  
  
  OBJECTIVE
  To determine the diagnostic value of indicators of renal blood flow as a marker of acute kidney injury in critically ill newborns.
  
  
  METHODS
  The study included 40 infants in critical condition. A clinical assessment of severity of the condition during admission was carried out with Neonatal Multiple Organ Dysfunction Score (NEOMOD) and Neonatal Therapeutic Intervention Scoring System (NTISS). All patients underwent evaluation of clinical and instrumental parameters, including ultrasound of the renal vessels, renal vascular resistance index and speed performance.
  
  
  CONCLUSIONS
  1) biochemical markers used in routine clinical practice were not sufficiently informative for the diagnosis of AKI. 2) For a more accurate assessment of the risk of AKI using serum creatinine, GFR calculation and evaluation on a scale RIFLE it is should be focused on performance standards, appropriate for gestational age and birth weight. 3) Evaluation of blood flow at a particular index in the resistance of the main renal arteries had the greatest predictive value and had a relatively high sensitivity and specificity for the diagnosis of AKI.
authors.forename: O V
authors.initials: OV
authors.lastname: Bessonova
authors.forename: A V
authors.initials: AV
authors.lastname: Golomidov
authors.forename: A V
authors.initials: AV
authors.lastname: Ivanova
authors.forename: A E
authors.initials: AE
authors.lastname: Furman
authors.forename: E V
authors.initials: EV
authors.lastname: Grigoriev
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology / Q000652:urine; D016638:Critical Illness; D042241:Early Diagnosis; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology / Q000652:urine; D007677:Kidney Function Tests; D012079:Renal Circulation / Q000502:physiology*; D012680:Sensitivity and Specificity