title: Antifungal potential of essential oil and ethanol extracts of Lonicera japonica Thunb. against dermatophytes.
abstract: The antifungal potential of essential oil and ethanolic leaf extracts of Lonicera japonica Thunb. was evaluated for controlling the growth of dermatophytes. The oil (1,000 ppm) and extracts (1,500 ppm) of L. japonica revealed 55.1-70.3 % and 40.1-65.5 % antidermatophytic effect against Microsporum canis KCTC 6348, 6349, 6591, Trichophyton rubrum KCTC 6345, 6352, 6375, Trichophyton mentagrophytes KCTC 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations ranging from 62.5-500 and 125-1,000 µg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytes as well as concentration and time-dependent kinetic inhibition of M. canis KCTC 6348. The results demonstrated that L. japonica oil and extracts could be potential sources of natural fungicides to protect human and animals from fungal infections.
authors.affiliation: Department of Applied Chemistry and Chemical Technology, Islamic University, Kushtia 7003, Bangladesh.
authors.forename: Atiqur
authors.initials: A
authors.lastname: Rahman
authors.affiliation: Department of Applied Chemistry and Chemical Technology, Islamic University, Kushtia 7003, Bangladesh.
authors.forename: Sharif M
authors.initials: SM
authors.lastname: Al-Reza
authors.affiliation: Department of Applied Chemistry and Chemical Technology, Islamic University, Kushtia 7003, Bangladesh.
authors.forename: Shah Alam
authors.initials: SA
authors.lastname: Siddiqui
authors.affiliation: Division of Plant Resources and Environment, College of Ecology and Environmental Sciences, Kyungpook National University, Republic of Korea.
authors.forename: Taehyun
authors.initials: T
authors.lastname: Chang
authors.affiliation: Department of Biotechnology, College of Engineering, Daegu University, Kyoungsan, Kyoungbook 712-714, Republic of Korea.
authors.forename: Sun Chul
authors.initials: SC
authors.lastname: Kang
keywords: Lonicera japonica Thunb.; antidermatophytic activity; essential oil; ethanolic extracts; skin infectious fungal pathogens