title: Failure to Validate a Multivariable Clinical Prediction Model to Identify Pediatric Intensive Care Unit Patients at High Risk for Candidemia.
abstract: We attempted to validate a previously derived clinical prediction rule for candidemia in the pediatric intensive care unit. This multicenter case control study did not identify significant association of candidemia with most of the previously identified predictors. Additional study in larger cohorts with other predictor variables is needed.
authors.affiliation: Division of Infectious Diseases.|the Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Pennsylvania.|Department of Pediatrics.|The Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
authors.forename: Brian T
authors.initials: BT
authors.lastname: Fisher
authors.affiliation: Division of Infectious Diseases.|the Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Pennsylvania.
authors.forename: Rachael K
authors.initials: RK
authors.lastname: Ross
authors.affiliation: Infectious Diseases Unit, 3rd Department of Pediatrics, Aristotle University School of Health Sciences and Hippokration Hospital, Thessaloniki, Greece.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Roilides
authors.affiliation: Infectious Diseases Section, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston.
authors.forename: Debra L
authors.initials: DL
authors.lastname: Palazzi
authors.affiliation: University of Colorado School of Medicine and Children's Hospital Colorado, Aurora.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Abzug
authors.affiliation: Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California.
authors.forename: Jill A
authors.initials: JA
authors.lastname: Hoffman
authors.affiliation: All Children's Hospital, St. Petersburg, Florida.
authors.forename: David M
authors.initials: DM
authors.lastname: Berman
authors.affiliation: Department of Epidemiology and Biostatistics, University of California San Francisco.
authors.forename: Priya A
authors.initials: PA
authors.lastname: Prasad
authors.affiliation: the Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Pennsylvania.|Department of Pediatrics.|The Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
authors.forename: A Russell
authors.initials: AR
authors.lastname: Localio
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
authors.forename: William J
authors.initials: WJ
authors.lastname: Steinbach
authors.affiliation: Pediatric Intensive Care Unit, Hippokration General Hospital, Thessaloniki, Greece.
authors.forename: Lambrini
authors.initials: L
authors.lastname: Vogiatzi
authors.affiliation: Infectious Diseases Section, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston.
authors.forename: Ankhi
authors.initials: A
authors.lastname: Dutta
authors.affiliation: Division of Infectious Diseases.|the Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Pennsylvania.|Department of Pediatrics.|The Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
authors.forename: Theoklis E
authors.initials: TE
authors.lastname: Zaoutis
mesh_terms: D000293:Adolescent; D058387:Candidemia / Q000175:diagnosis*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003661:Decision Support Techniques; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015278:Intensive Care Units, Pediatric; D008297:Male
keywords: ICU; candidemia; pediatric; prediction; validation