title: Controllable synthesis of nucleotide complex based on pH control: a small-molecule fluorescent probe as an auxiliary ligand to indicate the pre-organization of the nucleotide complex in solution.
abstract: Different CMP-bpe-M(ii) (CMP = cytidine monophosphate, bpe = bis(4-pyridyl)ethylene, M(ii) = Mn(2+) and Co(2+)) complexes are synthesized controllably based on pH control and well studied by X-ray single-crystal diffraction analysis. Interestingly, the suitable pH conditions are explored by considering the pre-organization modes of CMP, bpe, and M(2+) in aqueous solution by fluorescence spectroscopy based on acid/basic titration. The organic base bpe serves as a small-molecule fluorescent probe to indicate the changes of pre-organization modes along with the changes of the solution acidity. Furthermore, a perfect self-complementary sugar-base hydrogen bond is first reported based on the crystal structure analysis in this work, and different chiralities and SHG activities of CMP-bpe-Mn(ii) complexes obtained at different pH values are studied.
authors.affiliation: Key Laboratory of Clusters Science of Ministry of Education, School of Science, Beijing Institute of Technology, Beijing 100081, P. R. China. lihui@ bit.edu.cn.
authors.forename: Pei
authors.initials: P
authors.lastname: Zhou
authors.forename: Chong
authors.initials: C
authors.lastname: Wang
authors.forename: Qi-Ming
authors.initials: QM
authors.lastname: Qiu
authors.forename: Jian-Feng
authors.initials: JF
authors.lastname: Yao
authors.forename: Chuan-Fang
authors.initials: CF
authors.lastname: Sheng
authors.forename: Hui
authors.initials: H
authors.lastname: Li
mesh_terms: D060326:Chemistry Techniques, Synthetic; D003568:Cytidine Monophosphate / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008024:Ligands; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D012996:Solutions
chemical_list: D005456:Fluorescent Dyes; D008024:Ligands; D009942:Organometallic Compounds; D011725:Pyridines; D012996:Solutions; D003568:Cytidine Monophosphate; C023666:pyridine