title: Comparative clinical efficacy and safety of coded herbal medicine Dermovix in the management of patients with atopic dermatitis versus allopathic medicine.
abstract: Atopic dermatitis (AD) is defined as a chronic, highly pruritic inflammatory condition of skin. It is estimated that this disease may lead significant morbidity and also adversely affects the quality of life. Atopic dermatitis responds well to home treatment. Proper skin care reduces the need for medicines. Topical creams and oral antihistamines can be used to suppress the symptoms. The clinical trial was conducted on 60 patients in which 30 are control and 30 are test by taking written consent from them. Dermovix significantly improved skin symptoms associated with AD. This Dermovix ointment was safe and well tolerated in specified age group patients. Overall results of individual group were analyzed by using Paired sample t-test and level of significance of all the symptoms was calculated. Both the drugs showed similar efficacy and the calculated p value was p<0.05. Except in case of dry skin the test drug had shown not significant p value i.e. 0.407. When we compare all these and their effects and patients' complaints then Test group have shown better results because of no side effects.
authors.affiliation: Department of Basic Clinical Sciences, Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan.
authors.forename: Muhammad Amjad
authors.initials: MA
authors.lastname: Chishti
authors.affiliation: Department of Basic Clinical Sciences, Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan.
authors.forename: Ejaz
authors.initials: E
authors.lastname: Mohi-Ud-Din
authors.affiliation: Department of Basic Clinical Sciences, Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan /Jinnah University for Women, Karachi, Pakistan.
authors.forename: Khan
authors.initials: K
authors.lastname: Usmanghani
authors.affiliation: Department of Basic Clinical Sciences, Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan / Faculty of Medicine, Graduate School of Medical & Pharmaceutical Sciences for Research, University of Toyama, Toyama, Japan.
authors.forename: Allah
authors.initials: A
authors.lastname: Nawaz
authors.affiliation: Department of Basic Clinical Sciences, Faculty of Eastern Medicine, Hamdard University, Karachi, Pakistan.
authors.forename: Halima
authors.initials: H
authors.lastname: Nazar
authors.affiliation: Department of Pharmacy, The Islamia University of Bahawalpur, Pakistan.
authors.forename: Irshad
authors.initials: I
authors.lastname: Ahmad
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D000529:Complementary Therapies; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D005260:Female; D029001:Herbal Medicine; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D008517:Phytotherapy / Q000009:adverse effects
chemical_list: D009824:Ointments