title: Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model.
abstract: To determine the utility of oral swabs for diagnosing infection with Ebola virus, we used a guinea pig model and obtained daily antemortem and postmortem swab samples. According to quantitative reverse transcription PCR analysis, the diagnostic value was poor for antemortem swab samples but excellent for postmortem samples.
authors.forename: Jessica R
authors.initials: JR
authors.lastname: Spengler
authors.forename: Ayan K
authors.initials: AK
authors.lastname: Chakrabarti
authors.forename: JoAnn D
authors.initials: JD
authors.lastname: Coleman-McCray
authors.forename: Brock E
authors.initials: BE
authors.lastname: Martin
authors.forename: Stuart T
authors.initials: ST
authors.lastname: Nichol
authors.forename: Christina F
authors.initials: CF
authors.lastname: Spiropoulou
authors.forename: Brian H
authors.initials: BH
authors.lastname: Bird
mesh_terms: D000818:Animals; D042241:Early Diagnosis; D029043:Ebolavirus; D006168:Guinea Pigs; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D009055:Mouth / Q000821:virology*; D013048:Specimen Handling / Q000379:methods*
keywords: Ebola; guinea pig; oral swab; qRT-PCR; viral hemorrhagic fever; viruses; wild-type Ebola virus