title: The association of gasping and outcome, in out of hospital cardiac arrest: A systematic review and meta-analysis.
abstract: OBJECTIVE
  Gasping is common after cardiac arrest, and its frequency decreases over time. The aim of this study was to conduct a meta-analysis to evaluate the association of gasping and survival to discharge in patients who suffered out-of-hospital cardiac arrest.
  
  
  METHODS
  Relevant studies were identified by searching in PubMed, Medline, Embase, OVID, Web of Science and Google Scholar. Risk ratios (RR) and 95% confidence intervals (CI) were calculated to assess the association of gasping and on out-of-hospital cardiac arrest outcomes. Heterogeneity, subgroup analysis, sensitivity analysis and publication bias were explored.
  
  
  RESULTS
  Individual patient data was obtained from 10,797 participants suffered out-of-hospital cardiac arrest in five cohort studies of 4 articles. A fixed effects model suggested that patients with gasping were 3.525 times (95% CI: 3.028-4.104; P<0.01) more likely to survive to discharge than those without gasping, and there was no heterogeneity among studies (P=0.564). Also it may be a favorable factor for return of spontaneous circulation (RR: 2.170; 95% CI: 1.691, 2.785) with high heterogeneity (Q=5.26; P=0.022).
  
  
  CONCLUSIONS
  Findings of this meta-analysis demonstrated that gasping is common after cardiac arrest, and is associated with increased survival to discharge. Patients who are cardiac arrest with gasping should be promptly resuscitated.
authors.affiliation: Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University; Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation (No. BZ0370), 8# Worker's Stadium South Road, Chao-Yang District, Beijing 100020, China.
authors.forename: Lianxing
authors.initials: L
authors.lastname: Zhao
authors.affiliation: Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University; Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation (No. BZ0370), 8# Worker's Stadium South Road, Chao-Yang District, Beijing 100020, China. Electronic address: lcscyyy@163.com.
authors.forename: Chunsheng
authors.initials: C
authors.lastname: Li
authors.affiliation: Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University; Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation (No. BZ0370), 8# Worker's Stadium South Road, Chao-Yang District, Beijing 100020, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University; Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation (No. BZ0370), 8# Worker's Stadium South Road, Chao-Yang District, Beijing 100020, China.
authors.forename: Miaomiao
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University; Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation (No. BZ0370), 8# Worker's Stadium South Road, Chao-Yang District, Beijing 100020, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Shao
authors.affiliation: Department of Emergency Medicine, Beijing Chao-Yang Hospital, Capital Medical University; Beijing Key Laboratory of Cardiopulmonary Cerebral Resuscitation (No. BZ0370), 8# Worker's Stadium South Road, Chao-Yang District, Beijing 100020, China.
authors.forename: Yingying
authors.initials: Y
authors.lastname: Fang
mesh_terms: D004417:Dyspnea / Q000209:etiology*; D006801:Humans; D058687:Out-of-Hospital Cardiac Arrest / Q000150:complications* / Q000401:mortality; D010351:Patient Discharge; D015996:Survival Rate
keywords: Meta-analysis; Out-of-hospital cardiac arrest; Patient admission; Patient discharge; Respiration; Resuscitation