title: Mode of action of metabolites from Bacillus sp. strain IBA 33 on Geotrichum citri-aurantii arthroconidia.
abstract: Geotrichum citri-aurantii is a postharvest phytopathogenic fungus of lemons. We studied the mode of action of antifungal metabolites from Bacillus sp. strain IBA 33 on arthroconidia of G. citri-aurantii. These metabolites are lipopeptides belonging to the iturin family. Membrane permeabilization of G. citri-aurantii was analyzed and mitochondrial respiratory rate was evaluated. Disturbance of the plasma membrane promotes the leakage of many cellular components into the surrounding media, and mitochondrial membrane disorganization promotes the inhibition of the respiratory rate. Our findings provide insights into the ability of lipopeptides to suppress plant fungal pathogens and their possible agronomical applications.
authors.affiliation: Instituto de Biotecnología, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 465, 4000, Tucumán, República Argentina.|Instituto de Biotecnología, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 465, 4000, Tucumán, República Argentina.
authors.forename: María Antonieta
authors.initials: MA
authors.lastname: Gordillo
authors.affiliation: Instituto de Biotecnología, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 465, 4000, Tucumán, República Argentina.|Instituto de Biotecnología, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 465, 4000, Tucumán, República Argentina.
authors.forename: Antonio R
authors.initials: AR
authors.lastname: Navarro
authors.affiliation: Instituto de Biotecnología, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 465, 4000, Tucumán, República Argentina.|Instituto de Biotecnología, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 465, 4000, Tucumán, República Argentina.
authors.forename: María Cristina
authors.initials: MC
authors.lastname: Maldonado
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry; D001407:Bacillus / Q000737:chemistry*; D002462:Cell Membrane / Q000187:drug effects; D002957:Citrus / Q000382:microbiology*; D005516:Food Microbiology; D005519:Food Preservation; D005848:Geotrichum / Q000187:drug effects*; D008051:Lipid Bilayers / Q000737:chemistry; D055666:Lipopeptides / Q000737:chemistry; D046529:Microscopy, Electron, Transmission; D051336:Mitochondrial Membranes / Q000187:drug effects; D010539:Permeability; D011188:Potassium / Q000737:chemistry; D013172:Spores, Fungal / Q000187:drug effects
chemical_list: D000935:Antifungal Agents; D008051:Lipid Bilayers; D055666:Lipopeptides; D011188:Potassium
keywords: Bacillus; Geotrichum citri-aurantii; lipopeptides; membrane cytoplasmique; metabolites; métabolites; plasma membrane