title: Is scintigraphy necessary to detect migration of 125I seeds after brachytherapy for early prostate cancer?
abstract: BACKGROUND
  We investigated whether scintigraphy was superior to radiography for detecting migrated seeds after brachytherapy for prostate cancer.
  
  
  METHODS
  We studied 57 patients with early prostate cancer who were treated with free (125)I transperineal brachytherapy. Scintigraphy was used to detect seed migration on postoperative day (POD) 1, radiography was used on POD 2, and both tests were used on POD 30.
  
  
  RESULTS
  The total number of implanted seeds in this study was 3,753 in 57 patients. Overall, there were 19 seed migrations in 12 patients. On POD 1, there were 4 seed migrations in 4 patients that were detected by scintigraphy. On POD 2, there were 10 seed migrations in 9 patients that were detected by radiography. On POD 30, 17 seed migrations were detected in 10 patients by radiography and 18 seeds migrations were detected by scintigraphy. However, 1 seed migration which was located outside of the detectable range of radiography was detected only by scintigraphy.
  
  
  CONCLUSIONS
  Both scintigraphy and radiography have similar abilities to detect migrated seeds 1 month after (125)I brachytherapy for prostate cancer. While both tests have advantages and disadvantages, it is reasonable to only use radiography if scintigraphy is not available.
authors.affiliation: Department of Urology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo-to, 160-0023, Japan.
authors.forename: Yu
authors.initials: Y
authors.lastname: Odagaki
authors.affiliation: Department of Urology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo-to, 160-0023, Japan. mak_ohori@yahoo.co.jp.
authors.forename: Makoto
authors.initials: M
authors.lastname: Ohori
authors.affiliation: Department of Radiology, Tokyo Medical University, Tokyo-to, 160-0023, Japan.
authors.forename: Mana
authors.initials: M
authors.lastname: Yoshimura
authors.affiliation: Department of Urology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo-to, 160-0023, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Nakshima
authors.affiliation: Department of Urology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo-to, 160-0023, Japan.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Ohno
authors.affiliation: Department of Radiology, Tokyo Medical University, Tokyo-to, 160-0023, Japan.
authors.forename: Ryuji
authors.initials: R
authors.lastname: Mikami
authors.affiliation: Department of Radiology, Tokyo Medical University, Tokyo-to, 160-0023, Japan.
authors.forename: Hidetsugu
authors.initials: H
authors.lastname: Nakayama
authors.affiliation: Department of Radiology, Tokyo Medical University, Tokyo-to, 160-0023, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Tokuuye
authors.affiliation: Department of Urology, Tokyo Medical University, 6-7-1 Nishi-shinjuku, Shinjuku-ku, Tokyo-to, 160-0023, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Tachibana
mesh_terms: D000368:Aged; D001918:Brachytherapy; D005548:Foreign-Body Migration / Q000175:diagnosis*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D009366:Neoplasm Seeding; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000532:radiotherapy; D011877:Radionuclide Imaging / Q000379:methods*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D007457:Iodine Radioisotopes
keywords: Prostate cancer; Scintigraphy; Seed migration