title: Lymphocytic choriomeningitis virus infection induced by percutaneous exposure.
abstract: We report a case of acquired lymphocytic choriomeningitis virus (LCMV) infection due to an accidental percutaneous inoculation of LCMV at work. The injured worker developed a flu-like syndrome, followed by pericarditis and meningoencephalitis. Seroconversion was confirmed by ELISA. The patient made a complete recovery. We review measures undertaken to prevent a similar event and propose a follow-up protocol in the event of accidental LCMV exposure.
authors.affiliation: Department of Internal Medicine, CHUV, 1011 Lausanne, Switzerland, oriane.aebischer@chuv.ch.
authors.forename: O
authors.initials: O
authors.lastname: Aebischer
authors.affiliation: Department of Infectious Disease, CHUV, 1011 Lausanne, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Meylan
authors.affiliation: Department of Microbiology, CHUV, 1011 Lausanne, Switzerland.
authors.forename: S
authors.initials: S
authors.lastname: Kunz
authors.affiliation: Department of Preventive and Occupational Medicine, CHUV, 1011 Lausanne, Switzerland.
authors.forename: C
authors.initials: C
authors.lastname: Lazor-Blanchet
mesh_terms: D000062:Accidents, Occupational; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage*; D006801:Humans; D008216:Lymphocytic Choriomeningitis / Q000188:drug therapy* / Q000209:etiology / Q000821:virology; D008217:Lymphocytic choriomeningitis virus / Q000472:pathogenicity*; D008297:Male; D016602:Needlestick Injuries / Q000821:virology*; D016273:Occupational Exposure / Q000009:adverse effects*; D056990:Post-Exposure Prophylaxis; D017410:Practice Guidelines as Topic; D012254:Ribavirin / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D012254:Ribavirin
keywords: Accidents; laboratory workers; needlestick injuries.