title: Conducting Polymers for Neural Prosthetic and Neural Interface Applications.
abstract: Neural-interfacing devices are an artificial mechanism for restoring or supplementing the function of the nervous system, lost as a result of injury or disease. Conducting polymers (CPs) are gaining significant attention due to their capacity to meet the performance criteria of a number of neuronal therapies including recording and stimulating neural activity, the regeneration of neural tissue and the delivery of bioactive molecules for mediating device-tissue interactions. CPs form a flexible platform technology that enables the development of tailored materials for a range of neuronal diagnostic and treatment therapies. In this review, the application of CPs for neural prostheses and other neural interfacing devices is discussed, with a specific focus on neural recording, neural stimulation, neural regeneration, and therapeutic drug delivery.
authors.affiliation: Graduate School of Biomedical Engineering, The University of New South Wales, Sydney, NSW, 2052, Australia.
authors.forename: Rylie
authors.initials: R
authors.lastname: Green
authors.affiliation: Biomedical Engineering Department Materials Science & Engineering Department, Chemical Engineering Department Materials Research Institute and Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, 16802, USA.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Abidian
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry; D004566:Electrodes; D005782:Gels / Q000737:chemistry; D006801:Humans; D058117:Neural Prostheses; D009474:Neurons / Q000502:physiology; D011108:Polymers / Q000737:chemistry*; D012038:Regeneration
chemical_list: D001672:Biocompatible Materials; D004337:Drug Carriers; D005782:Gels; D011108:Polymers
keywords: conducting polymers; neural interfaces; neural recording; neural stimulation