title: Keeping time in the brain: Autism spectrum disorder and audiovisual temporal processing.
abstract: A growing area of interest and relevance in the study of autism spectrum disorder (ASD) focuses on the relationship between multisensory temporal function and the behavioral, perceptual, and cognitive impairments observed in ASD. Atypical sensory processing is becoming increasingly recognized as a core component of autism, with evidence of atypical processing across a number of sensory modalities. These deviations from typical processing underscore the value of interpreting ASD within a multisensory framework. Furthermore, converging evidence illustrates that these differences in audiovisual processing may be specifically related to temporal processing. This review seeks to bridge the connection between temporal processing and audiovisual perception, and to elaborate on emerging data showing differences in audiovisual temporal function in autism. We also discuss the consequence of such changes, the specific impact on the processing of different classes of audiovisual stimuli (e.g. speech vs. nonspeech, etc.), and the presumptive brain processes and networks underlying audiovisual temporal integration. Finally, possible downstream behavioral implications, and possible remediation strategies are outlined. Autism Res 2016, 9: 720-738. © 2015 International Society for Autism Research, Wiley Periodicals, Inc.
authors.affiliation: Department of Psychology, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Ryan A
authors.initials: RA
authors.lastname: Stevenson
authors.affiliation: Department of Psychology, York University, Toronto, Ontario, Canada.
authors.forename: Magali
authors.initials: M
authors.lastname: Segers
authors.affiliation: Department of Psychology, University of Toronto, Toronto, Ontario, Canada.|Rotman Research Institute, Toronto, Ontario, Canada.
authors.forename: Susanne
authors.initials: S
authors.lastname: Ferber
authors.affiliation: Department of Psychology, University of Toronto, Toronto, Ontario, Canada.|Rotman Research Institute, Toronto, Ontario, Canada.
authors.forename: Morgan D
authors.initials: MD
authors.lastname: Barense
authors.affiliation: Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.|Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, Tennessee.
authors.forename: Stephen
authors.initials: S
authors.lastname: Camarata
authors.affiliation: Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, Tennessee.|Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, Tennessee.|Vanderbilt Brain Institute, Vanderbilt University Medical Center, Nashville, Tennessee.|Department of Psychology, Vanderbilt University, Nashville, Tennessee.|Department of Psychiatry, Vanderbilt University Medical Center, Nashville, Tennessee.
authors.forename: Mark T
authors.initials: MT
authors.lastname: Wallace
mesh_terms: D000161:Acoustic Stimulation; D001307:Auditory Perception; D000067877:Autism Spectrum Disorder / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology; D006801:Humans; D010775:Photic Stimulation; D014796:Visual Perception
keywords: cognitive neuroscience; developmental psychology; low-level perception; social cognition