title: SCHMIDT'S SYNDROME IN A 32 YEARS OLD FEMALE.
abstract: In polyglandular autoimmune (PGA) syndromes, there is immune dysfunction of two or more endocrine glands. Immunity mediated disorders of non-endocrine organs may also be seen. These syndromes are of two main types: type I and type II. We are reporting this case of a 32 years old lady who presented initially with hypothyroidism for many years and received thyroid replacement therapy. After that she was married and had children. After an interval of about seven years of the initial diagnosis of hypothyroidism, she was hospitalized in first trimester of pregnancy for severe vertigo, syncopal episodes and hypotension. She responded well to intravenous fluids and steroids. Further endocrine related, investigations revealed Addison's disease and the above episode were retrospectively diagnosed as Addisonian crisis. Thus the patient was diagnosed as Schmidt's Syndrome (Autoimmune polyendocrine syndrome type 2) since 2009.
authors.forename: Abdul Latif
authors.initials: AL
authors.lastname: Khattak
authors.forename: Abdul Latif
authors.initials: AL
authors.lastname: Khatak
authors.forename: Waqar
authors.initials: W
authors.lastname: Ali
authors.forename: Salman
authors.initials: S
authors.lastname: Saleem
authors.forename: Zameer Ahmad
authors.initials: ZA
authors.lastname: Nayyer
authors.forename: Muhammad
authors.initials: M
authors.lastname: Idris
authors.forename: Mohammad
authors.initials: M
authors.lastname: Idrees
authors.forename: Naseer Ahmad
authors.initials: NA
authors.lastname: Khan
authors.forename: Nayyer
authors.initials: N
authors.lastname: Ahmad
authors.forename: Waseem
authors.initials: W
authors.lastname: Pasha
mesh_terms: D000328:Adult; D005260:Female; D005440:Fluid Therapy / Q000379:methods*; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D016884:Polyendocrinopathies, Autoimmune / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications
chemical_list: D005938:Glucocorticoids