title: Synthesis and Catalytic Use of Gold(I) Complexes Containing a Hemilabile Phosphanylferrocene Nitrile Donor.
abstract: Removal of the chloride ligand from [AuCl(1-κP)] (2) containing a P-monodentate 1'-(diphenylphosphanyl)-1-cyanoferrocene ligand (1), by using silver(I) salts affords cationic complexes of the type [Au(1)]X, which exist either as cyclic dimers [Au(1)]2 X2 (3 a, X=SbF6 ; 3 c, X=NTf2 ) or linear coordination polymers [Au(1)]n Xn (3 a', X=SbF6 ; 3 b', X=ClO4 ), depending on anion X and the isolation procedure. As demonstrated for 3 a', the polymers can be readily cleaved by the addition of donors, such as Cl(-) , tetrahydrothiophene (tht) or 1, giving rise to the parent compound 2, [Au(tht)(1-κP)][SbF6 ] (5 a) or [Au(1-κP)2 ][SbF6 ] (4 a), respectively, of which the last two compounds can also be prepared by stepwise replacement of tht in [Au(1-κP)2 ][SbF6 ]. The particular combination of a firmly coordinated (phosphane) and a dissociable (nitrile) donor moieties renders complexes 3/3' attractive for catalysis because they can serve as shelf-stable precursors of coordinatively unsaturated Au(I) fragments, analogous to those that result from the widely used [Au(PR3 )(RCN)]X catalysts. The catalytic properties of the Au-1 complexes were evaluated in model annulation reactions, such as the synthesis of 2,3-dimethylfuran from (Z)-3-methylpent-2-en-4-yn-1-ol and oxidative cyclisation of alkynes with nitriles to produce 2,5-disubstituted 1,3-oxazoles. Of the compounds tested (2, 3 a', 3 b', 3 a, 4 a and 5 a), the best results were consistently achieved with dimer 3 c, which has good solubility in organic solvents and only one firmly bound donor at the gold atom. This compound was advantageously used in the key steps of annuloline and rosefuran syntheses.
authors.affiliation: Department of Inorganic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 2030, 12840 Prague (Czech Republic).
authors.forename: Karel
authors.initials: K
authors.lastname: Škoch
authors.affiliation: Department of Inorganic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 2030, 12840 Prague (Czech Republic).
authors.forename: Ivana
authors.initials: I
authors.lastname: Císařová
authors.affiliation: Department of Inorganic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 2030, 12840 Prague (Czech Republic). stepnic@natur.cuni.cz.
authors.forename: Petr
authors.initials: P
authors.lastname: Štěpnička
keywords: gold; homogeneous catalysis; metallocenes; phosphane ligands; structure elucidation