title: To adhere or not to adhere: Rates and reasons of medication adherence in hematological cancer patients.
abstract: To conduct a comprehensive review to examine among hematological cancer patients: (1) rates of adherence to self-administered cancer treatments; and (2) factors impacting on their adherence. Fifty two eligible publications were identified. The majority focused on Chronic Myeloid Leukaemia (CML) (n=40) and Acute Lymphoid Leukaemia (ALL) (n=11) patients. Adherence rates varied and depended on the definition and measures used. Patient understanding about their disease and treatment, and forgetting to take their medication impacted on patients' level of adherence; while the use of reminders reduced forgetfulness. There is a lack of valid and reliable information relating to medication adherence of hematological cancer patients. Based on the limited data available we provide a profile of CML and ALL patients at potential risk of medication non-adherence, as well as a proposed checklist that can be used by health care providers in assessing and supporting patients in adhering to their medication.
authors.affiliation: Priority Research Centre for Health Behaviour, Faculty of Health, The University of Newcastle & Hunter Medical Research Institute, Callaghan, NSW 2308, Australia. Electronic address: alix.hall@newcastle.edu.au.
authors.forename: Alix E
authors.initials: AE
authors.lastname: Hall
authors.affiliation: Priority Research Centre for Health Behaviour, Faculty of Health, The University of Newcastle & Hunter Medical Research Institute, Callaghan, NSW 2308, Australia. Electronic address: chris.paul@newcastle.edu.au.
authors.forename: Chris
authors.initials: C
authors.lastname: Paul
authors.affiliation: Priority Research Centre for Health Behaviour, Faculty of Health, The University of Newcastle & Hunter Medical Research Institute, Callaghan, NSW 2308, Australia. Electronic address: jamie.bryant@newcastle.edu.au.
authors.forename: Jamie
authors.initials: J
authors.lastname: Bryant
authors.affiliation: Priority Research Centre for Health Behaviour, Faculty of Health, The University of Newcastle & Hunter Medical Research Institute, Callaghan, NSW 2308, Australia. Electronic address: marita.lynagh@newcastle.edu.au.
authors.forename: Marita C
authors.initials: MC
authors.lastname: Lynagh
authors.affiliation: Haematology Unit, Calvary Mater Hospital Newcastle, Waratah, NSW 2298, Australia; School of Medicine and Public Health, Faculty of Health, The University of Newcastle, Callaghan, NSW 2308, Australia. Electronic address: philip.rowlings@newcastle.edu.au.
authors.forename: Philip
authors.initials: P
authors.lastname: Rowlings
authors.affiliation: Haematology Unit, Calvary Mater Hospital Newcastle, Waratah, NSW 2298, Australia; School of Medicine and Public Health, Faculty of Health, The University of Newcastle, Callaghan, NSW 2308, Australia. Electronic address: anoop.enjeti@calvarymater.org.au.
authors.forename: Anoop
authors.initials: A
authors.lastname: Enjeti
authors.affiliation: Priority Research Centre for Health Behaviour, Faculty of Health, The University of Newcastle & Hunter Medical Research Institute, Callaghan, NSW 2308, Australia. Electronic address: hannah.small@newcastle.edu.au.
authors.forename: Hannah
authors.initials: H
authors.lastname: Small
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D019337:Hematologic Neoplasms / Q000188:drug therapy*; D006801:Humans; D055118:Medication Adherence
chemical_list: D000970:Antineoplastic Agents
keywords: Adherence; Compliance; Hemato-oncology; Hematological cancer; Medication