title: Differences in Activation Area Within Brodmann Area 2 Caused by Pressure Stimuli on Fingers and Joints: In Case of Male Subjects.
abstract: In this study, a constant pressure stimulus was applied on the 3 joints (first [p1], second [p2], and third [p3] joints) of 4 fingers (index, middle, ring, and little fingers), and the activation areas within Brodmann area 2 (BA 2) were compared for these different fingers and joints by using functional magnetic resonance imaging. Eight healthy male college students (25.4 ± 1.32 years) participated in the study. Each session was composed of 3 blocks, and each block was composed of a Control phase (30 seconds) and a Pressure phase (30 seconds). No pressure stimulus was applied in the Control phase, during which the subjects would simply lay comfortably with their eyes closed. In the Pressure phase, a pressure stimulus was applied onto one of the joints of the selected finger. For each finger and joint, BA 2 areas activated by the pressure stimulus were extracted by the region of interest method. There was a significant difference in the activation areas for the different fingers (P = .042) as well as for the different joints (P = .050). The activation area decreased in the order of the little, index, and middle fingers, as well as in the order of p1, p3, and p2.
authors.affiliation: From the Department of Biomedical Engineering (M-HC, H-SK, J-HB, J-CL, S-JP, U-HJ, S-YG, S-CC), Research Institute of Biomedical Engineering, College of Biomedical & Health Science, Konkuk University, Chungju; Department of Human and Systems Engineering (S-PK), Ulsan National Institute of Science and Technology, Ulsan; and Department of Information and Communication Engineering (D-WL), Dongguk University, Seoul, South Korea.
authors.forename: Mi-Hyun
authors.initials: MH
authors.lastname: Choi
authors.forename: Hyung-Sik
authors.initials: HS
authors.lastname: Kim
authors.forename: Ji-Hye
authors.initials: JH
authors.lastname: Baek
authors.forename: Jung-Chul
authors.initials: JC
authors.lastname: Lee
authors.forename: Sung-Jun
authors.initials: SJ
authors.lastname: Park
authors.forename: Ul-Ho
authors.initials: UH
authors.lastname: Jeong
authors.forename: Seon-Young
authors.initials: SY
authors.lastname: Gim
authors.forename: Sung-Phil
authors.initials: SP
authors.lastname: Kim
authors.forename: Dae-Woon
authors.initials: DW
authors.lastname: Lim
authors.forename: Soon-Cheol
authors.initials: SC
authors.lastname: Chung
mesh_terms: D000328:Adult; D005260:Female; D005384:Finger Joint / Q000502:physiology*; D064368:Healthy Volunteers; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008465:Mechanoreceptors / Q000502:physiology*; D011312:Pressure; D013003:Somatosensory Cortex / Q000502:physiology*; D055698:Touch Perception / Q000502:physiology*; D055815:Young Adult