title: Molecular magnetic resonance imaging in cancer.
abstract: The ability to identify key biomolecules and molecular changes associated with cancer malignancy and the capacity to monitor the therapeutic outcome against these targets is critically important for cancer treatment. Recent developments in molecular imaging based on magnetic resonance (MR) techniques have provided researchers and clinicians with new tools to improve most facets of cancer care. Molecular imaging is broadly described as imaging techniques used to detect molecular signature at the cellular and gene expression levels. This article reviews both established and emerging molecular MR techniques in oncology and discusses the potential of these techniques in improving the clinical cancer care. It also discusses how molecular MR, in conjunction with other structural and functional MR imaging techniques, paves the way for developing tailored treatment strategies to enhance cancer care.
authors.affiliation: Sidra Medical and Research Center, 26999, Doha, Qatar. mharis@sidra.org.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Haris
authors.affiliation: Sidra Medical and Research Center, 26999, Doha, Qatar. syadav@sidra.org.
authors.forename: Santosh K
authors.initials: SK
authors.lastname: Yadav
authors.affiliation: All India Institute of Medical Sciences, New Delhi, India. arshiriz.sgpgi@gmail.com.
authors.forename: Arshi
authors.initials: A
authors.lastname: Rizwan
authors.affiliation: Center for Biomedical Engineering, Indian Institute of Technology, Delhi, India. anups.minhas@gmail.com.
authors.forename: Anup
authors.initials: A
authors.lastname: Singh
authors.affiliation: Sidra Medical and Research Center, 26999, Doha, Qatar. ewang@sidra.org.
authors.forename: Ena
authors.initials: E
authors.lastname: Wang
authors.affiliation: Center for Magnetic Resonance and Optical Imaging, Department of Radiology, University of Pennsylvania, Philadlephia, PA, 19104, USA. harih@mail.med.upenn.edu.
authors.forename: Hari
authors.initials: H
authors.lastname: Hariharan
authors.affiliation: Center for Magnetic Resonance and Optical Imaging, Department of Radiology, University of Pennsylvania, Philadlephia, PA, 19104, USA. krr@mail.med.upenn.edu.
authors.forename: Ravinder
authors.initials: R
authors.lastname: Reddy
authors.affiliation: Sidra Medical and Research Center, 26999, Doha, Qatar. fmarincola@sidra.org.
authors.forename: Francesco M
authors.initials: FM
authors.lastname: Marincola
mesh_terms: D020869:Gene Expression Profiling; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D057054:Molecular Imaging; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology*