title: An epileptic focus location method based on ECoG.
abstract: Epilepsy is a neurological disorder characterized by the sudden abnormal discharging of brain neurons that can lead to encephalographic (EEG) abnormalities. In this study, data was obtained from epileptic patients with intracranial depth electrodes and analyzed using wavelet entropy algorithms in order to locate the epileptic foci. Significant increases in the wavelet entropy of the epileptic signals were identified during multiple episodes of clinical seizures. The results indicated that the algorithm was capable of identifying entropy changes in the epileptic sources. Furthermore, the correlations among the electrocorticogram (ECoG) signals of different channels determined using the amplitude-amplitude coupling method verified that the epileptic foci exhibited significantly higher coupling strengths. Thus, cross frequency coupling (CFC) could be an inspiration to energy and signal transitive mode of seizure and, thereby, improve diagnostic processes.
authors.affiliation: School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Tang
authors.affiliation: School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
authors.forename: Xiying
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
authors.forename: Dongqin
authors.initials: D
authors.lastname: Cai
authors.affiliation: School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
authors.forename: Juncheng
authors.initials: J
authors.lastname: Du
authors.affiliation: School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
authors.forename: Weifeng
authors.initials: W
authors.lastname: Liu
mesh_terms: D001921:Brain / Q000473:pathology; D000069280:Electrocorticography / Q000379:methods*; D019277:Entropy; D004827:Epilepsy / Q000175:diagnosis*; D006801:Humans; D012640:Seizures / Q000175:diagnosis*; D058067:Wavelet Analysis
keywords: CFC; ECoG; Epilepsy; correlation; wavelet entropy