title: Mandibular clear cell odontogenic carcinoma.
abstract: BACKGROUND
  Clear cell odontogenic carcinoma (CCOC) is a rare intraosseous carcinoma of the jaw; only 81 cases have been reported in the English literatures.
  
  
  METHODS
  We reported an additional case and reviewed the existing literature. A 70-year-old woman presented with a large painful radiolucent mandibular lesion from the right canine to the left angle area through the midline. No metastatic lymph nodes or distant metastases were detected. She underwent wide surgical resection and reconstruction with a composite fibula free flap. She had no recurrence or metastasis after 18 months.
  
  
  CONCLUSIONS
  CCOC occurs predominantly in women in their 50s-70s in the mandible. Painless swelling is the most common symptom, followed by pain, teeth loosening, and paresthesia. CCOC has a good prognosis after surgery. In large mandibular CCOC, wide resection and composite fibula free flap reconstruction is the treatment of choice.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul, 110-768, Korea. smiledoc83@gmail.com.
authors.forename: Ik Jae
authors.initials: IJ
authors.lastname: Kwon
authors.affiliation: Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul, 110-768, Korea. smin5@snu.ac.kr.|Oral and Maxillofacial Microvascular Reconstruction LAB, Brong Ahafo Regional Hospital, Sunayni, Ghana. smin5@snu.ac.kr.
authors.forename: Soung Min
authors.initials: SM
authors.lastname: Kim
authors.affiliation: Oral and Maxillofacial Microvascular Reconstruction LAB, Brong Ahafo Regional Hospital, Sunayni, Ghana.
authors.forename: Emmanuel Kofi
authors.initials: EK
authors.lastname: Amponsah
authors.affiliation: Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul, 110-768, Korea. myoungh@snu.ac.kr.
authors.forename: Hoon
authors.initials: H
authors.lastname: Myoung
authors.affiliation: Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, 101 Daehak-ro, Jongno-gu, Seoul, 110-768, Korea. leejongh@snu.ac.kr.
authors.forename: Jong Ho
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Oral Pathology, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea. sukkeunlee@hanmail.net.
authors.forename: Suk Keun
authors.initials: SK
authors.lastname: Lee
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000473:pathology* / Q000601:surgery; D000368:Aged; D005260:Female; D006801:Humans; D008339:Mandibular Neoplasms / Q000473:pathology* / Q000601:surgery; D009808:Odontogenic Tumors / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D019651:Plastic Surgery Procedures