title: Draft genome sequence of blaVeb-1, blaoxa-10 producing multi-drug resistant (MDR) Pseudomonas aeruginosa strain VRFPA09 recovered from bloodstream infection.
abstract: Pseudomonas aeruginosa (P. aeruginosa) bacteremia causes significant mortality rate due to emergence of multidrug resistant (MDR) nosocomial infections. We report the draft genome sequence of P. aeruginosa strain VRFPA09, a human bloodstream isolate, phenotypically proven as MDR strain. Whole genome sequencing on VRFPA09, deciphered betalactamase encoding blav(eb-1) and bla(OXA-10) genes and multiple drug resistance, virulence factor encoding genes.
authors.affiliation: Department of Microbiology, L & T Microbiology Research Centre, Vision Research Foundation, Sankara Nethralaya, Tamil Nadu, India .
authors.forename: Nandagopal
authors.initials: N
authors.lastname: Murugan
authors.affiliation: Department of Microbiology, L & T Microbiology Research Centre, Vision Research Foundation, Sankara Nethralaya, Tamil Nadu, India .
authors.forename: Jambulingam
authors.initials: J
authors.lastname: Malathi
authors.affiliation: Centre for Bioinformatics, Vision Research Foundation, Sankara Nethralaya, Tamil Nadu, India .
authors.forename: Vetrivel
authors.initials: V
authors.lastname: Umashankar
authors.affiliation: Department of Microbiology, L & T Microbiology Research Centre, Vision Research Foundation, Sankara Nethralaya, Tamil Nadu, India .
authors.forename: Hajib NarahariRao
authors.initials: HN
authors.lastname: Madhavan
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016470:Bacteremia / Q000382:microbiology*; D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D029968:Escherichia coli Proteins; D006801:Humans; D008826:Microbial Sensitivity Tests; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics*; D047090:beta-Lactams / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; D047090:beta-Lactams; C119424:beta-lactamase VEB-1, E coli; D001618:beta-Lactamases; C000609545:beta-lactamase VEB-1, Pseudomonas aeruginosa; C000600037:beta-lactamase blaOXA-10, Pseudomonas aeruginosa
keywords: Pseudomonas aeruginosa; blood; extended spectrum betalactamases; next generation sequencing