title: Chelate-Thiolate-Coordinate Ligands Modulating the Configuration and Electrochemical Property of Dinitrosyliron Complexes (DNICs).
abstract: As opposed to the reversible redox reaction ({Fe(NO)2 }(10) reduced-form DNIC [(NO)2 Fe(S(CH2 )3 S)](2-) (1)⇌{Fe(NO)2 }(9) oxidized-form [(NO)2 Fe(S(CH2 )3 S)](-) ), the chemical oxidation of the {Fe(NO)2 }(10) DNIC [(NO)2 Fe(S(CH2 )2 S)](2-) (2) generates the dinuclear {Fe(NO)2 }(9) -{Fe(NO)2 }(9) complex [(NO)2 Fe(μ-SC2 H4 S)2 Fe(NO)2 ](2-) (3) bridged by two terminal [SC2 H4 S](2-) ligands. On the basis of the Fe K-edge pre-edge energy and S K-edge XAS, the oxidation of complex 1 yielding [(NO)2 Fe(S(CH2 )3 S)](-) is predominantly a metal-based oxidation. The smaller S1-Fe1-S2 bond angle of 94.1(1)° observed in complex 1 (S1-Fe1-S2 88.6(1)° in complex 2), compared to the bigger bond angle of 100.9(1)° in the {Fe(NO)2 }(9) DNIC [(NO)2 Fe(S(CH2 )3 S)](-) , may be ascribed to the electron-rich {Fe(NO)2 }(10) DNIC preferring a restricted bite angle to alleviate the electronic donation of the chelating thiolate to the electron-rich {Fe(NO)2 }(10) core. The extended transition state and natural orbitals for chemical valence (ETS-NOCV) analysis on the edt-/pdt-chelated {Fe(NO)2 }(9) and {Fe(NO)2 }(10) DNICs demonstrates how two key bonding interactions, that is, a FeS covalent σ bond and thiolate to the Fe d z 2 charge donation, between the chelating thiolate ligand and the {Fe(NO)2 }(9/10) core could be modulated by the backbone lengths of the chelating thiolate ligands to tune the electrochemical redox potential (E1/2 =-1.64 V for complex 1 and E1/2 =-1.33 V for complex 2) and to dictate structural rearrangement/chemical transformations (S-Fe-S bite angle and monomeric vs. dimeric DNICs).
authors.affiliation: Department of Chemistry and Frontier Research Center, of Fundamental and Applied Science of Matters, National Tsing Hua University, Hsinchu 30013 (Taiwan).
authors.forename: Shih-Wey
authors.initials: SW
authors.lastname: Yeh
authors.affiliation: Department of Chemistry and Frontier Research Center, of Fundamental and Applied Science of Matters, National Tsing Hua University, Hsinchu 30013 (Taiwan).
authors.forename: Chih-Wei
authors.initials: CW
authors.lastname: Lin
authors.affiliation: Department of Chemistry and Frontier Research Center, of Fundamental and Applied Science of Matters, National Tsing Hua University, Hsinchu 30013 (Taiwan).
authors.forename: Bai-Heng
authors.initials: BH
authors.lastname: Liu
authors.affiliation: Department of Chemistry and Frontier Research Center, of Fundamental and Applied Science of Matters, National Tsing Hua University, Hsinchu 30013 (Taiwan).
authors.forename: Chih-Chin
authors.initials: CC
authors.lastname: Tsou
authors.affiliation: Department of Chemistry and Frontier Research Center, of Fundamental and Applied Science of Matters, National Tsing Hua University, Hsinchu 30013 (Taiwan).
authors.forename: Ming-Li
authors.initials: ML
authors.lastname: Tsai
authors.affiliation: Department of Chemistry and Frontier Research Center, of Fundamental and Applied Science of Matters, National Tsing Hua University, Hsinchu 30013 (Taiwan). wfliaw@mx.nthu.edu.tw.
authors.forename: Wen-Feng
authors.initials: WF
authors.lastname: Liaw
keywords: bioinorganic chemistry; chelates; dinitrosyl iron complexes; nitric oxide