title: Phenolics and Polyphenolics from Melastomataceae Species.
abstract: The Melastomataceae family, the seventh largest flowering plants, has been studied in several fronts of natural product chemistry, including terpenoids, simple phenolics, flavonoids, quinones, lignans and their glycosides, as well as a vast range of tannins or polyphenols. This review concerns the phenolic and polyphenolic metabolites described in the literature for several genera of this family, the mode of isolation and purification, and the structure elucidation of these new natural products that has been achieved by extensive spectral analyses, including ESI-MS, ¹H-, (13)C-NMR spectra and two-dimensional experiments, COSY, TOCSY, J-resolved, NOESY, HMQC, DEPT, and HMBC, as well as chemical and enzymatic degradations and the chemotaxonomic meaning. Finally, a general biogenetic pathway map for ellagitannins is proposed on the bases of the most plausible free radical C-O oxidative coupling.
authors.affiliation: Grupo de Investigación en Productos Naturales y Alimentos (GIPNA), Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad del Valle, Edificio 320, Oficina 2096, Ciudad Universitaria-Meléndez, Calle 13 No. 100-00, Cali 760032, Colombia. diana.ocampo@ucaldas.edu.co.|Departamento de Química, Facultad de Ciencias Exactas y Naturales, Universidad de Caldas, Calle 65 No. 26-10, Manizales 170004, Colombia. diana.ocampo@ucaldas.edu.co.
authors.forename: Diana Marcela Ocampo
authors.initials: DM
authors.lastname: Serna
authors.affiliation: Grupo de Investigación en Productos Naturales y Alimentos (GIPNA), Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad del Valle, Edificio 320, Oficina 2096, Ciudad Universitaria-Meléndez, Calle 13 No. 100-00, Cali 760032, Colombia. jose.isaza@correounivalle.edu.co.
authors.forename: José Hipólito Isaza
authors.initials: JH
authors.lastname: Martínez
mesh_terms: D005419:Flavonoids / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry; D035322:Melastomataceae / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D059808:Polyphenols / Q000737:chemistry*
chemical_list: D005419:Flavonoids; D006027:Glycosides; D010636:Phenols; D059808:Polyphenols
keywords: anthocyanins; biogenesis; flavonoids; hydrolizable tannins; melastoflorins; melastomataceae; nobotannins; polyphenols