title: The role of zinc in acute pyelonephritis.
abstract: This study was conducted to determine the serum concentration of zinc in children with acute pyelonephritis. Serum zinc levels of 60 children with acute pyelonephritis and 60 healthy children were compared. Acute pyelonephritis was diagnosed using Tc-99m dimercaptosuccinic acid (DMSA) renal scan. Serum zinc levels were measured by the atomic absorption flame spectrophotometry. The levels in question in the case and control groups were 70.73 ± 14.15 and 87.61 ± 12.68 mcg/dL, respectively (P=0.001). There was no correlation between serum zinc level with inflammatory markers, severity of acute pyelonephritis and duration of the disease. This study showed that there is a correlation between serum zinc level and acute pyelonephritis. Zinc would therefore appear to play a certain role in the pathogenesis of acute pyelonephritis.
authors.affiliation: Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Mahyar
authors.affiliation: Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Parviz
authors.initials: P
authors.lastname: Ayazi
authors.affiliation: Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Shahin
authors.initials: S
authors.lastname: Farzadmanesh
authors.affiliation: Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Sahmani
authors.affiliation: Maternity and Child Health, Metabolic Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Sonia
authors.initials: S
authors.lastname: Oveisi
authors.affiliation: Department of Pediatrics, Qazvin Children hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Victoria
authors.initials: V
authors.lastname: Chegini
authors.affiliation: Department of Statistics, Qazvin University of Medical Sciences, Qazvin, Iran.
authors.forename: Shiva
authors.initials: S
authors.lastname: Esmaeily
mesh_terms: D000208:Acute Disease; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006776:Hospitals, Pediatric; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D008297:Male; D011237:Predictive Value of Tests; D011704:Pyelonephritis / Q000097:blood* / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D015032:Zinc / Q000097:blood*
chemical_list: D015415:Biomarkers; D015032:Zinc