title: Integrated design of micro force sensor oriented to cell micro-operation.
abstract: BACKGROUND
  During the process of cell micro operation, the contact force between the entry needle and the cell membrane is usually a very small area to be tested.
  
  
  OBJECTIVE
  These two features have been utilized to design a high precision micro force sensor to provide a force feedback in the process of cell micro operation.
  
  
  METHODS
  However, PVDF (Polyvinylidene Fluoride) has continued to display both a wide range of frequency response and a highly sensitive transform between force and electricity. In this paper a charge signal is obtained. In order to transform the charge signal into a voltage signal, a signal processing circuit was designed. The data acquisition card PCI-6221 (National Instruments) was used. It was employed to collect the voltage signal.
  
  
  RESULTS
  The resultant micro force sensor was calibrated by using a rating test.
  
  
  CONCLUSIONS
  The experimental test results demonstrated that the sensitivity and linearity of the designed micro force sensor were higher than the sensitivity and linearity of a traditional piezoelectric sensor.
authors.forename: Zhen
authors.initials: Z
authors.lastname: An
authors.forename: Chaoqun
authors.initials: C
authors.lastname: Xiang
authors.forename: Jinming
authors.initials: J
authors.lastname: Wang
authors.forename: Liping
authors.initials: L
authors.lastname: Dong
authors.forename: Lina
authors.initials: L
authors.lastname: Hao
mesh_terms: D002462:Cell Membrane; D004560:Electricity; D004867:Equipment Design; D005818:Genetic Engineering / Q000379:methods*; D006801:Humans; D055595:Mechanical Phenomena; D009339:Needles; D011145:Polyvinyls / Q000737:chemistry*; D005465:Fluorocarbon Polymers
chemical_list: D011145:Polyvinyls; C024865:polyvinylidene fluoride; D005465:Fluorocarbon Polymers
keywords: Cell micro-operation; PVDF; charge amplifier; micro force sensor