title: Physical exercise prevents short and long-term deficits on aversive and recognition memory and attenuates brain oxidative damage induced by maternal deprivation.
abstract: It is known from previous research that physical exercise prevents long-term memory deficits induced by maternal deprivation in rats. But we could not assume similar effects of physical exercise on short-term memory, as short- and long-term memories are known to result from some different memory consolidation processes. Here we demonstrated that, in addition to long-term memory deficit, the short-term memory deficit resultant from maternal deprivation in object recognition and aversive memory tasks is also prevented by physical exercise. Additionally, one of the mechanisms by which the physical exercise influences the memory processes involves its effects attenuating the oxidative damage in the maternal deprived rats' hippocampus and prefrontal cortex.
authors.affiliation: Physiology Research Group, Stress, Memory & Behavior Lab, Federal University of Pampa, BR 472, Km 592, Po Box 118, 97500-970 Uruguaiana, RS, Brazil.
authors.forename: Ben-Hur
authors.initials: BH
authors.lastname: Neves
authors.affiliation: Physiology Research Group, Stress, Memory & Behavior Lab, Federal University of Pampa, BR 472, Km 592, Po Box 118, 97500-970 Uruguaiana, RS, Brazil.
authors.forename: Jefferson
authors.initials: J
authors.lastname: Menezes
authors.affiliation: Physiology Research Group, Stress, Memory & Behavior Lab, Federal University of Pampa, BR 472, Km 592, Po Box 118, 97500-970 Uruguaiana, RS, Brazil.
authors.forename: Mauren Assis
authors.initials: MA
authors.lastname: Souza
authors.affiliation: Physiology Research Group, Stress, Memory & Behavior Lab, Federal University of Pampa, BR 472, Km 592, Po Box 118, 97500-970 Uruguaiana, RS, Brazil; Graduate Program in Biological Sciences: Physiology, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil. Electronic address: pamelacarpes@unipampa.edu.br.
authors.forename: Pâmela B
authors.initials: PB
authors.lastname: Mello-Carpes
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D005978:Glutathione / Q000378:metabolism; D006624:Hippocampus / Q000503:physiopathology*; D008297:Male; D008426:Maternal Deprivation; D008569:Memory Disorders / Q000503:physiopathology / Q000517:prevention & control; D057567:Memory, Long-Term / Q000502:physiology; D008570:Memory, Short-Term / Q000502:physiology; D018384:Oxidative Stress / Q000502:physiology; D010805:Physical Conditioning, Animal / Q000502:physiology* / Q000523:psychology*; D017397:Prefrontal Cortex / Q000503:physiopathology*; D017208:Rats, Wistar; D017382:Reactive Oxygen Species / Q000378:metabolism; D021641:Recognition, Psychology / Q000502:physiology*; D012420:Running / Q000502:physiology / Q000523:psychology; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
chemical_list: D017382:Reactive Oxygen Species; D017392:Thiobarbituric Acid Reactive Substances; D005978:Glutathione
keywords: Antioxidants; Inhibitory avoidance; Lipid peroxidation; Object recognition; Reactive oxygen species