title: Spinal cord injury-induced pain: mechanisms and treatments.
abstract: Pain is a common consequence of a spinal cord injury (SCI) and has a major impact on quality of life through its impact on physical function, mood and participation in work, recreational and social activities. Several types of pain typically present following SCI with central neuropathic pain being a frequent and difficult to manage occurrence. Despite advances in our understanding of the mechanisms contributing to this type of pain and an increasing number of trials examining treatment efficacy, our ability to relieve neuropathic SCI pain is still very limited. Optimal management relies upon an integrated approach that uses a combination of pharmacological and nonpharmacological options.
authors.affiliation: Pain Management Service, HammondCare, Sydney, NSW 2000, Australia.|Pain Medicine, Sydney Medical School-Northern, The University of Sydney, Sydney, Australia.|Greenwich Hospital, Greenwich, NSW 2065, Australia.
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Siddall
authors.affiliation: State Spinal Cord Injury Service, NSW Agency for Clinical Innovation, Chatswood, NSW 2057, Australia.|John Walsh Centre for Rehabilitation Research, Sydney Medical School-Northern, The University of Sydney, Sydney, Australia.
authors.forename: James W
authors.initials: JW
authors.lastname: Middleton
mesh_terms: D000818:Animals; D001921:Brain / Q000503:physiopathology; D006801:Humans; D009437:Neuralgia / Q000628:therapy*; D010146:Pain / Q000209:etiology* / Q000503:physiopathology; D059408:Pain Management; D011788:Quality of Life; D013116:Spinal Cord / Q000503:physiopathology; D013119:Spinal Cord Injuries / Q000150:complications* / Q000503:physiopathology; D016896:Treatment Outcome
keywords: CNS; management; neuropathic; pain; spinal cord injuries