title: 3D Printed Microtransporters: Compound Micromachines for Spatiotemporally Controlled Delivery of Therapeutic Agents.
abstract: Functional compound micromachines are fabricated by a design methodology using 3D direct laser writing and selective physical vapor deposition of magnetic materials. Microtransporters with a wirelessly controlled Archimedes screw pumping mechanism are engineered. Spatiotemporally controlled collection, transport, and delivery of micro particles, as well as magnetic nanohelices inside microfluidic channels are demonstrated.
authors.affiliation: Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH 8092, Switzerland.|School of Electronics and Information Engineering, Liaoning University of Science and Technology, Anshan, 114051, China.
authors.forename: Tian-Yun
authors.initials: TY
authors.lastname: Huang
authors.affiliation: Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH 8092, Switzerland.
authors.forename: Mahmut Selman
authors.initials: MS
authors.lastname: Sakar
authors.affiliation: Wyss Institute for Biologically Inspired Engineering, School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02318, USA.
authors.forename: Angelo
authors.initials: A
authors.lastname: Mao
authors.affiliation: Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH 8092, Switzerland.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Petruska
authors.affiliation: Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH 8092, Switzerland.
authors.forename: Famin
authors.initials: F
authors.lastname: Qiu
authors.affiliation: School of Electronics and Information Engineering, Liaoning University of Science and Technology, Anshan, 114051, China.
authors.forename: Xue-Bo
authors.initials: XB
authors.lastname: Chen
authors.affiliation: Department of Electrical, Computer, and Biomedical Engineering, Department of Chemical Engineering, University of Rhode Island, Kingston, RI, 02881, USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Kennedy
authors.affiliation: Wyss Institute for Biologically Inspired Engineering, School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02318, USA.
authors.forename: David
authors.initials: D
authors.lastname: Mooney
authors.affiliation: Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH 8092, Switzerland.
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Nelson
mesh_terms: D045744:Cell Line, Tumor; D016503:Drug Delivery Systems / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D056656:Lab-On-A-Chip Devices; D058185:Magnetite Nanoparticles; D055616:Microtechnology / Q000295:instrumentation / Q000379:methods*; D066330:Printing, Three-Dimensional; D059015:Wireless Technology
chemical_list: D058185:Magnetite Nanoparticles
keywords: 3D printing; magnetism; micromachines; microrobotics; targeted cell delivery; targeted drug delivery