title: Delayed Development of Intracranial Hypertension After Discontinuation of Tetracycline Treatment for Acne Vulgaris.
abstract: A 14-year-old girl presented with a history of left-sided headache and acute bilateral blurred vision. She had a remote history of oral tetracycline use for the treatment of acne vulgaris, which had been discontinued for 1 month. The patient was diagnosed with drug-induced intracranial hypertension (IH) and treated with oral acetazolamide with subsequent resolution of symptoms. IH, a known rare complication of the tetracycline class of antibiotics, can also have a delayed presentation after discontinuation of the medication.
authors.affiliation: Department of Ophthalmology, Hotel Dieu Hospital, Queen's University, Kingston, Ontario, Canada.
authors.forename: Christine
authors.initials: C
authors.lastname: Law
authors.forename: Gary L
authors.initials: GL
authors.lastname: Yau
authors.forename: Martin
authors.initials: M
authors.lastname: ten Hove
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D013752:Tetracycline / Q000009:adverse effects*; D014786:Vision Disorders / Q000139:chemically induced* / Q000175:diagnosis; D014792:Visual Acuity / Q000187:drug effects; D058609:Visual Field Tests; D014794:Visual Fields; D028761:Withholding Treatment
chemical_list: D000900:Anti-Bacterial Agents; D002257:Carbonic Anhydrase Inhibitors; D013752:Tetracycline; D000086:Acetazolamide