title: Congenital Tuberculosis Complicated by Hemophagocytic Lymphohistiocytosis.
abstract: We present the case of a male infant with congenital tuberculosis in a nonendemic setting complicated by hemophagocytic lymphohistiocytosis, who was treated successfully with antituberculous therapy and corticosteroids. We review the pediatric literature concerning the unusual association of these 2 rare conditions.
authors.affiliation: From the *Infectious Diseases Unit, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; †Division of Pediatric Infectious Diseases, Department of Pediatrics, University of British Columbia, BC Children's Hospital, Vancouver, British Columbia, Canada; ‡Murdoch Children's Research Institute; §Department of General Medicine, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; ¶Paediatric Department, Likas Women's and Children's Hospital, Sabah, Malaysia; and ‖Department of Paediatrics, The University of Melbourne, Parkville, Victoria, Australia.
authors.forename: Joshua
authors.initials: J
authors.lastname: Osowicki
authors.forename: Shiqi
authors.initials: S
authors.lastname: Wang
authors.forename: Christopher
authors.initials: C
authors.lastname: McKenzie
authors.forename: Carolyn
authors.initials: C
authors.lastname: Marshall
authors.forename: Jye
authors.initials: J
authors.lastname: Gard
authors.forename: Wong
authors.initials: W
authors.lastname: Ke Juin
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Steer
authors.forename: Tom G
authors.initials: TG
authors.lastname: Connell
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D016896:Treatment Outcome; D014376:Tuberculosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission*
chemical_list: D000305:Adrenal Cortex Hormones; D000995:Antitubercular Agents