title: [18F]-NaF PET/CT imaging in cardiac amyloidosis.
abstract: Cardiac amyloidosis (CA) is recognized as a common cause of restrictive cardiomyopathy and heart failure due to the deposition of insoluble proteins in the myocardial interstitium. We emphasize the role of [18F]-sodium fluoride (NaF) PET/CT as a potential noninvasive tool to identify and differentiate the transthyretin-related cardiac amyloidosis from the light-chain cardiac amyloidosis. We report cases of a 73-year-old man and a 75-year-old woman followed in our center for congestive heart failure with marked alteration of the left ventricular ejection fraction due to familial transthyretin Val122Ile cardiac amyloidosis and light-chain cardiac amyloidosis, respectively, confirmed on endomyocardial biopsy.
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France. axel.vandergucht@gmail.com.|Mondor Amyloidosis Network, 94000, Créteil, France. axel.vandergucht@gmail.com.|DHU ATVB, 94000, Créteil, France. axel.vandergucht@gmail.com.|Department of Nuclear Medicine, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France. axel.vandergucht@gmail.com.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France. axel.vandergucht@gmail.com.
authors.forename: Axel
authors.initials: A
authors.lastname: Van Der Gucht
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France.|Department of Cardiology, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Arnault
authors.initials: A
authors.lastname: Galat
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|Department of Nuclear Medicine, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Jean
authors.initials: J
authors.lastname: Rosso
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France.|Department of Cardiology, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Aziz
authors.initials: A
authors.lastname: Guellich
authors.affiliation: Cardiovascular Magnetic Resonance Department, Institut Cardiovasculaire Paris Sud, Hôpital Privé Jacques Cartier, Ramsay-Générale de Santé, 91300, Massy, France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Garot
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France.|Department of Cardiology, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Diane
authors.initials: D
authors.lastname: Bodez
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France.|Department of Neurology, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Violaine
authors.initials: V
authors.lastname: Plante-Bordeneuve
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France.|Department of Cardiology, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Luc
authors.initials: L
authors.lastname: Hittinger
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France.|Department of Cardiology, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Dubois-Randé
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|Department of Nuclear Medicine, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Eva
authors.initials: E
authors.lastname: Evangelista
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|Department of Nuclear Medicine, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Myriam
authors.initials: M
authors.lastname: Sasanelli
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|Department of Nuclear Medicine, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Julia
authors.initials: J
authors.lastname: Chalaye
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|Department of Nuclear Medicine, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Meignan
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|Department of Nuclear Medicine, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Itti
authors.affiliation: UPEC, AP-HP Henri-Mondor Teaching Hospital, 94000, Créteil, France.|Mondor Amyloidosis Network, 94000, Créteil, France.|DHU ATVB, 94000, Créteil, France.|INSERM U955, GRC Réseau Amylose Mondor, 94000, Créteil, France.|Department of Cardiology, AP-HP, Henri-Mondor Teaching Hospital, 51 Ave. du Mal de Lattre de Tassigny, 94010, Créteil, France.
authors.forename: Thibaud
authors.initials: T
authors.lastname: Damy
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000000981:diagnostic imaging*; D057791:Cardiac Imaging Techniques / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D005462:Fluorine Radioisotopes; D006331:Heart Diseases / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012969:Sodium Fluoride
chemical_list: D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D012969:Sodium Fluoride
keywords: PET/CT; [18F]-NaF; cardiac amyloidosis; protein deposition