title: Toxic encephalopathy due to paradichlorobenzene toxicity: a case report and review of imaging characteristics.
abstract: Neurotoxicity following paradichlorobenzene (PDCB) exposure is rare and can occur in patients with pica and mothball or toilet cake ingestion. We present a rare case of toxic encephalopathy due to PDCB mothball inhalation and ingestion and describe the rapidly progressive leukoencephalopathy seen on computed tomography, magnetic resonance, and magnetic resonance spectroscopy. Given the nonspecificity of clinical and imaging findings, it is important for radiologists to maintain a high index of suspicion for toxic encephalopathy.
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, NY.
authors.forename: Elizabeth K
authors.initials: EK
authors.lastname: Weidman
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, NY.
authors.forename: A John
authors.initials: AJ
authors.lastname: Tsiouris
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, NY. Electronic address: laheier@med.cornell.edu.
authors.forename: Linda A
authors.initials: LA
authors.lastname: Heier
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology*; D002722:Chlorobenzenes / Q000633:toxicity*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D020258:Neurotoxicity Syndromes / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography
chemical_list: D002722:Chlorobenzenes; C018511:4-dichlorobenzene
keywords: Brain; Leukoencephalopathy; Paradichlorobenzene; Toxic encephalopathy