title: Massive mediastinal cryptococcosis in a young immunocompetent patient.
abstract: Pulmonary cryptococcosis with lymph node involvement is relatively rare in immunocompetent patients. We report a case of pulmonary cryptococcosis with massive mediastinal lymphadenopathy in an immunocompetent young patient. In this report, a 17-year-old boy presented with high-grade fever and persistent cough. Chest X-ray and computed tomography showed massive mediastinal lymphadenopathy. Endobronchial ultrasound-guided transbronchial needle aspiration revealed histological evidence of cryptococcal lymphadenitis. He was treated with liposomal amphotericin B plus flucytosine followed by fluconazole and recovered.
authors.affiliation: Department of Respiratory Medicine, Nagoya University Graduate School of Medicine Nagoya, Japan.
authors.forename: Shotaro
authors.initials: S
authors.lastname: Okachi
authors.affiliation: Department of Respiratory Medicine, Nagoya University Graduate School of Medicine Nagoya, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Wakahara
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital Nagoya, Japan.
authors.forename: Daizo
authors.initials: D
authors.lastname: Kato
authors.affiliation: Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases Tokyo, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Umeyama
authors.affiliation: Department of Infectious Diseases, Nagoya University Hospital Nagoya, Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yagi
authors.affiliation: Department of Respiratory Medicine, Nagoya University Graduate School of Medicine Nagoya, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Hasegawa
keywords: Cryptococcosis; EBUS-TBNA; lymphadenopathy; mediastinum; pulmonary