title: The Effects of Psychological Stress on Depression.
abstract: Major depressive disorder is a serious mental disorder that profoundly affects an individual's quality of life. Although the aetiologies underlying this disorder remain unclear, an increasing attention has been focused on the influence imposed by psychological stress over depression. Despite limited animal models of psychological stress, significant progress has been made as to be explicated in this review to elucidate the physiopathology underlying depression and to treat depressive symptoms. Therefore, we will review classical models along with new methods that will enrich our knowledge of this disorder.
authors.forename: Longfei
authors.initials: L
authors.lastname: Yang
authors.forename: Yinghao
authors.initials: Y
authors.lastname: Zhao
authors.forename: Yicun
authors.initials: Y
authors.lastname: Wang
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Xingyi
authors.initials: X
authors.lastname: Zhang
authors.forename: Bingjin
authors.initials: B
authors.lastname: Li
authors.affiliation: Jilin Provincial Key Laboratory on Molecular and Chemical Genetic, The Second Hospital of Jilin University, 218 Ziqiang street Changchun China 130041.
authors.forename: Ranji
authors.initials: R
authors.lastname: Cui
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D003863:Depression / Q000503:physiopathology / Q000628:therapy*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D004195:Disease Models, Animal; D006801:Humans; D011788:Quality of Life; D013315:Stress, Psychological / Q000503:physiopathology* / Q000628:therapy*