title: Effect of Electroacupuncture on Transcutaneous Oxygen Partial Pressure During Hyperbaric Oxygen Therapy in Healthy Individuals.
abstract: BACKGROUND
  The goal of hyperbaric oxygen therapy (HBOT) is to increase the oxygen (O₂) supply to the body significantly. Because of the toxic side effects and complications of hyperbaric oxygen (HBO₂), the environmental pressure and treatment time must be restricted. The research team hypothesized that other therapies administered during HBOT could safely improve the value of the arterial oxygen partial pressure (PaO₂) during HBOT and improve its therapeutic effect.
  
  
  OBJECTIVE
  The study intended to investigate whether electroacupuncture (EA) while receiving HBOT had a greater effect for healthy individuals than HBOT or EA alone or EA combined with normobaric pure oxygen (pure O₂).
  
  
  METHODS
  The research team designed a randomized, controlled trial.
  
  
  METHODS
  The study was performed in the Department of Hyperbaric Medicine at the No. 401 Hospital of the People's Liberation Army in Qingdao, China.
  
  
  METHODS
  A total of 81 volunteers were recruited. After thorough physical examination and laboratory testing, 21 volunteers were excluded from the study. Participants included 60 healthy volunteers.
  
  
  METHODS
  Participants were randomly assigned to 1 of 4 groups of 15 participants each: (1) an HBOT group, (2) an EA group, (3) an EA During HBOT group, and (4) an EA Combined With Pure O₂group.
  
  
  METHODS
  Because at the current technology level a blood gas analyzer cannot test PaO₂during HBOT, transcutaneous oxygen partial pressure (PtcO₂) of the participants was tested instead. Before, during, and after EA, variations in PtcO₂were monitored in each group.
  
  
  RESULTS
  For the EA During HBOT group, (1) the increase in PtcO₂during EA was significantly greater than that observed for the other 3 groups (P > .05).
  
  
  CONCLUSIONS
  The EA During HBOT method provided improvements in the efficacy, safety, and tolerability of HBOT, and the study's results partially demonstrated the accuracy of the research team's hypothesis that EA therapy applied during HBOT could safely improve the value of PtcO₂(PaO₂) during HBOT and produce a greater therapeutic effect.
authors.forename: Lan
authors.initials: L
authors.lastname: Qu
authors.forename: Yong
authors.initials: Y
authors.lastname: Ye
authors.forename: Chunfeng
authors.initials: C
authors.lastname: Li
authors.forename: Guangkai
authors.initials: G
authors.lastname: Gao
mesh_terms: D000328:Adult; D002681:China; D015671:Electroacupuncture / Q000379:methods*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D008297:Male; D010100:Oxygen; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D010313:Partial Pressure; D012016:Reference Values
chemical_list: D010100:Oxygen