title: Changes in Aortic Volumes Following Endovascular Sealing of Abdominal Aortic Aneurysms With the Nellix Endoprosthesis.
abstract: OBJECTIVE
  To investigate the effects on aortic volumes of endovascular aneurysm sealing (EVAS) with the Nellix device.
  
  
  METHODS
  Twenty-five consecutive patients (mean age 78±7 years; 17 men) with abdominal aortic aneurysms containing thrombus were treated with EVAS. Their pre- and post-EVAS computed tomography (CT) scans were reviewed to document volume changes in the entire aneurysmal aorta, the lumen, and the intraluminal thrombus. The changes are reported as the mean and 95% confidence interval (CI).
  
  
  RESULTS
  Total aortic volume was greater on postoperative scans by a mean 17 mL (95% CI 10.0 to 23.5, p<0.001). The volume occupied by the endobags was greater than the preoperative lumen volume by a mean 28 mL (95% CI 24.7 to 31.7, p=0.002). Postoperatively, the aortic volume occupied by thrombus had decreased by a mean 11 mL (95% CI 4.7 to 18.2, p<0.001). There were good correlations between changes in aneurysm and thrombus volumes (r=0.864, p<0.001), between the planning CT/EVAS time interval and the change in aneurysm volume (r=0.640, p=0.001), and between the planning CT/EVAS time interval and the change in thrombus volume (r=0.567, p=0.003).
  
  
  CONCLUSIONS
  There are significant changes in aortic volumes post EVAS. These changes may be a direct consequence of the technique and have implications for the planning and performance of EVAS.
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Usman
authors.initials: U
authors.lastname: Shaikh
authors.affiliation: Department of Interventional Radiology, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Tze Y
authors.initials: TY
authors.lastname: Chan
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Olufemi
authors.initials: O
authors.lastname: Oshin
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Richard G
authors.initials: RG
authors.lastname: McWilliams
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK.
authors.forename: Robert K
authors.initials: RK
authors.lastname: Fisher
authors.affiliation: Department of Radiography, University of Salford, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: England
authors.affiliation: Liverpool Vascular and Endovascular Service, Royal Liverpool University Hospital, Liverpool, UK f.torella@liverpool.ac.uk.
authors.forename: Francesco
authors.initials: F
authors.lastname: Torella
mesh_terms: D000368:Aged; D001012:Aorta, Abdominal / Q000473:pathology*; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D057510:Endovascular Procedures / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D009929:Organ Size; D011183:Postoperative Complications / Q000473:pathology*; D012189:Retrospective Studies
keywords: abdominal aortic aneurysm; aortic lumen; computed tomography; endovascular aneurysm sealing; thrombus; volume change