title: Effect of Bone Cement Implantation on Haemodynamics in Elderly Patients and Preventive Measure in Cemented Hemiarthroplasty.
abstract: This study was to investigate the influence of bone cement implantation on haemodynamics and the preventive effect of epinephrine hydrochloride on pulmonary embolism in elderly patients with cemented semihip replacement. 128 patients were retrospectively analyzed. The patients were treated with (group A, 64 cases) or without (group B, 64 cases) epinephrine hydrochloride saline. The monitoring indicators included systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), and pulse oxygen saturation (SPO2). The indicators of the two groups were compared before and 1, 2, 3, 4, 5, 6, 7, 8, 9, and 10 minutes after bone cement implantation. Analysis of variance and SNK-q test were used for the statistical analysis. Blood pressure and SPO2 of group B decreased with statistical difference (P < 0.05) and HR increased without statistical significance, comparing with those of group A. In group A, SBP, DBP, MAP, HR, and SPO2 after bone cement implantation did not change significantly at each time point comparing with before implantation (P > 0.05). Bone cement implantation has significant influence on hemodynamics in elderly patients with hemiarthroplasty. Flushing the bone marrow cavity with saline epinephrine hydrochloride is an effective measure to reduce the incidence of bone cement pulmonary embolism.
authors.affiliation: Department of Emergency Orthopaedics, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China.
authors.forename: Xiangbei
authors.initials: X
authors.lastname: Qi
authors.affiliation: Department of Emergency Orthopaedics, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China.
authors.forename: Yingze
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Emergency Orthopaedics, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China.
authors.forename: Jinshe
authors.initials: J
authors.lastname: Pan
authors.affiliation: Department of Emergency Orthopaedics, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China.
authors.forename: Lijie
authors.initials: L
authors.lastname: Ma
authors.affiliation: Department of Emergency Orthopaedics, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Emergency Orthopaedics, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China.
authors.forename: Jianzhao
authors.initials: J
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000187:drug effects*; D001843:Bone Cements / Q000009:adverse effects* / Q000627:therapeutic use; D004837:Epinephrine / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D062785:Hemiarthroplasty / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D008297:Male; D019736:Prostheses and Implants; D011655:Pulmonary Embolism / Q000188:drug therapy / Q000517:prevention & control*; D012189:Retrospective Studies
chemical_list: D001843:Bone Cements; D004837:Epinephrine