title: Isolated central nervous system Whipple's disease: Two cases.
abstract: Although it is an orphan disease, isolated central nervous system Whipple's disease is one of the "must be known" conditions in neurology because it belongs to the list of "treatable disorders". Here, we present two cases which highlight the importance of early diagnosis. Additionally, we provide a discussion on up to date diagnostic approach to this life-threatening disorder.
authors.affiliation: Hacettepe University, Department of Neurology, Ankara, Turkey. Electronic address: atayvural@gmail.com.
authors.forename: Atay
authors.initials: A
authors.lastname: Vural
authors.affiliation: Hacettepe University, Department of Neurology, Ankara, Turkey. Electronic address: npinaracar@gmail.com.
authors.forename: Nazire Pinar
authors.initials: NP
authors.lastname: Acar
authors.affiliation: Hacettepe University, Department of Pathology, Ankara, Turkey. Electronic address: figensoylemez@yahoo.com.
authors.forename: Figen
authors.initials: F
authors.lastname: Soylemezoglu
authors.affiliation: Hacettepe University, Department of Radiology, Ankara, Turkey. Electronic address: karlioguz@yahoo.com.
authors.forename: Kader K
authors.initials: KK
authors.lastname: Oguz
authors.affiliation: Hacettepe University, Department of Radiology, Ankara, Turkey.
authors.forename: Neşe
authors.initials: N
authors.lastname: Dericioğlu
authors.affiliation: Hacettepe University, Department of Neurology, Ankara, Turkey. Electronic address: esensaka@hacettepe.edu.tr.
authors.forename: Esen
authors.initials: E
authors.lastname: Saka
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001259:Ataxia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D002443:Ceftriaxone / Q000627:therapeutic use; D002494:Central Nervous System Infections / Q000175:diagnosis* / Q000188:drug therapy; D004660:Encephalitis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D008061:Whipple Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D002443:Ceftriaxone; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
keywords: Central nervous system; Histopathology; Infection; Magnetic resonance imaging; Whipple's disease