title: Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles.
abstract: BACKGROUND
  Pregnancy rate with IVF cycle is almost 22%. Many investigations perform to increase this rate in IVF. Various factors affect the result of IVF cycles. One of these factors could be uterine contractions that expel transferred embryo. Ritodrine is a beta mimetic agent that can block and decrease uterine contractions.
  
  
  OBJECTIVE
  The objective of this study was to determine ritodrine effectiveness for increasing the implantation rate in IVF cycles, and its probable mechanisms in decreasing uterine contractions as well.
  
  
  METHODS
  A total of 100 patients of IVF-ET cycles were divided randomly in two groups in a university hospital, Hamadan, Iran. The case group were prescribed ritodrine 10 mg / bid orally after oocyte retrieval until 10 days. The control group didn't received ridotrine.
  
  
  RESULTS
  In ritodrine group 14% of patients and in control group 16% had positive β-hCG test (p-value>0.5).
  
  
  CONCLUSIONS
  Ritodrine did not improve the implantation rate in IVF-ET cycles.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Soghra
authors.initials: S
authors.lastname: Rabiee
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Marziyyeh
authors.initials: M
authors.lastname: Farimani
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Ahmadi
keywords: IVF-ET; Implantation rate; Ritodrine