title: Impact of Eye Cosmetics on the Eye, Adnexa, and Ocular Surface.
abstract: Despite the fact that cosmetic products undergo rigorous testing to ensure they are safe for human use, some users report mild discomfort following their application. The cutaneous changes, such as allergic dermatitis, are well reported, but the ocular changes associated with eye cosmetic use are less so. Some pigmented cosmetic products may accumulate within the lacrimal system and conjunctivae over many years of use, but immediate reports of eye discomfort after application are most common. Changes to the tear film and its stability may occur shortly after application, and contact lens wearers can also be affected by lens spoliation from cosmetic products. Additionally, creams used in the prevention of skin aging are often applied around the eyes, and retinoids present in these formulations can have negative effects on meibomian gland function and may be a contributing factor to dry eye disease. The aim of this review is to summarize current knowledge regarding the impact of cosmetic products on the eye, ocular surface, and tear film.
authors.affiliation: Centre for Contact Lens Research, School of Optometry and Vision Science (A.N., L.J.), University of Waterloo, Canada; and School of Optometry and Vision Sciences (K.E., R.V.N., C.P.), College of Biomedical and Life Sciences, Cardiff University, Cardiff, United Kingdom.
authors.forename: Alison
authors.initials: A
authors.lastname: Ng
authors.forename: Katharine
authors.initials: K
authors.lastname: Evans
authors.forename: Rachel V
authors.initials: RV
authors.lastname: North
authors.forename: Lyndon
authors.initials: L
authors.lastname: Jones
authors.forename: Christine
authors.initials: C
authors.lastname: Purslow
mesh_terms: D000485:Allergens / Q000009:adverse effects; D000818:Animals; D000975:Antioxidants / Q000009:adverse effects; D000069580:Bimatoprost / Q000009:adverse effects; D001762:Blepharitis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D003228:Conjunctiva / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D003229:Conjunctival Diseases / Q000209:etiology; D003261:Contact Lenses; D000075202:Contraindications; D003358:Cosmetics / Q000009:adverse effects* / Q000494:pharmacology / Q000633:toxicity; D015352:Dry Eye Syndromes / Q000209:etiology / Q000503:physiopathology; D005123:Eye / Q000187:drug effects* / Q000382:microbiology* / Q000473:pathology* / Q000503:physiopathology*; D015817:Eye Infections / Q000209:etiology / Q000382:microbiology; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology / Q000503:physiopathology; D008537:Meibomian Glands / Q000187:drug effects / Q000503:physiopathology; D008925:Mites / Q000382:microbiology; D012176:Retinoids / Q000009:adverse effects; D012867:Skin / Q000382:microbiology / Q000503:physiopathology; D013501:Surface-Active Agents / Q000009:adverse effects; D013666:Tears / Q000502:physiology
chemical_list: D000485:Allergens; D000975:Antioxidants; D003358:Cosmetics; D012176:Retinoids; D013501:Surface-Active Agents; D000069580:Bimatoprost