title: The use of anticoagulants in morbidly obese patients.
abstract: Due to its constantly growing incidence, obesity is an increasingly serious social and medical problem. Available data on the use of novel oral anticoagulants in morbidly obese and obese patients are very limited. However, we tried to summarize the available knowledge on the use of anticoagulants in this subpopulation of patients in everyday clinical practice. Studies on the clinical use of anticoagulants provide a poor basis for any adjustment of doses in obese patients as compared to patients with normal body weight. In our opinion, further studies are required in this particular population.
authors.affiliation: Department of Inter nal Medicine and Car diology with the Center for Diagnosis and T reatment of Venous Thromboembolism, Medical University of Warsaw, Poland. jdomienik@tlen.pl.
authors.forename: Justyna
authors.initials: J
authors.lastname: Domienik-Karłowicz
authors.forename: Piotr
authors.initials: P
authors.lastname: Pruszczyk
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D050110:Bariatric Surgery; D054796:Drug Dosage Calculations; D006801:Humans; D009767:Obesity, Morbid / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants
keywords: anticoagulant drugs; bariatric surgery; factor Xa inhibitors; heparin; morbid obesity; obesity