title: A New Diterpene Glycoside: 15α-Hydroxy-Rebaudioside M Isolated from Stevia rebaudiana.
abstract: In a continued search for novel diterpenoid glycosides, we recently isolated and characterized a Rebaudioside M derivative with a hydroxyl group at position 15 in the central diterpene core from an extract of Stevia rebaudiana Bertoni. Here we report the complete structure elucidation of 15α-hydroxy-Rebaudioside M (2) on the basis of NMR (1H, 13C, COSY, HSQC-DEPT, HMBC, 1D TOCSY, NOESY) and mass spectral data. Steviol glycoside with a hydroxyl group at C-15 in the central diterpene core has not been previously reported.
authors.forename: Indra
authors.initials: I
authors.lastname: Prakash
authors.forename: Gil
authors.initials: G
authors.lastname: Ma
authors.forename: Cynthia
authors.initials: C
authors.lastname: Bunders
authors.forename: Krishna P
authors.initials: KP
authors.lastname: Devkota
authors.forename: Romila D
authors.initials: RD
authors.lastname: Charan
authors.forename: Catherine
authors.initials: C
authors.lastname: Ramirez
authors.forename: Tara M
authors.initials: TM
authors.lastname: Snyder
authors.forename: Christopher
authors.initials: C
authors.lastname: Priedemann
mesh_terms: D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification; D036625:Stevia / Q000737:chemistry*
chemical_list: C000602584:15alpha-hydroxy-rebaudioside M; D004224:Diterpenes; D006027:Glycosides