title: Dental Implants in Patients with Sjögren's Syndrome.
abstract: BACKGROUND
  Limited evidence is available for applying dental implants in Sjögren's syndrome (SS) patients.
  
  
  OBJECTIVE
  This study aims to retrospectively assess clinical outcome of implant therapy in a cohort of well-classified patients with SS.
  
  
  METHODS
  All SS patients attending the University Medical Center Groningen for follow-up (n = 406) were asked whether they had implants. In SS patients with implants peri-implant health and implant survival was recorded and compared with data from matched healthy controls. Patients' symptoms, health-related quality of life, oral functioning, and satisfaction were assessed using validated questionnaires.
  
  
  RESULTS
  Of the responding SS patients (n = 335), 21% was provided with implants. Of these 69 SS patients, 50 SS patients were willing to join our study. In SS patients, peri-implant health was reasonably good with minor marginal bone loss and a peri-implantitis prevalence of 14%, comparable with healthy controls. Implant survival was 97% (median follow-up 46 months) [IQR 26;73], and overall patients' satisfaction was high. Oral functioning correlated negatively with dryness, patients' satisfaction, and chewing ability in SS patients.
  
  
  CONCLUSIONS
  Implant therapy is common in our cohort of SS patients. In spite of shortcomings of our retrospective analysis, implants in SS patients seem to perform comparable with implants in healthy patients.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. a.korfage@umcg.nl.
authors.forename: Anke
authors.initials: A
authors.lastname: Korfage
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Gerry M
authors.initials: GM
authors.lastname: Raghoebar
authors.affiliation: Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Suzanne
authors.initials: S
authors.lastname: Arends
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Petra M
authors.initials: PM
authors.lastname: Meiners
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Anita
authors.initials: A
authors.lastname: Visser
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.|Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Frans Gm
authors.initials: FG
authors.lastname: Kroese
authors.affiliation: Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Hendrika
authors.initials: H
authors.lastname: Bootsma
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
authors.forename: Arjan
authors.initials: A
authors.lastname: Vissink
mesh_terms: D000368:Aged; D015921:Dental Implants; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012859:Sjogren's Syndrome / Q000150:complications* / Q000601:surgery
chemical_list: D015921:Dental Implants
keywords: Sjögren's syndrome; dental implants; health-related quality of life; oral rehabilitation; patient satisfaction