title: Hepatitis B virus reactivation with a rituximab-containing regimen.
abstract: Rituximab is currently used not only in the treatment of B-cell lymphoma but also for various other diseases, including autoimmune diseases, post-transplant graft vs host disease, and rejection following kidney transplants. Due to rituximab's widespread use, great progress has been made regarding research into complications that arise from its use, one of the most serious being the reactivation of hepatitis B virus (HBV), and efforts continue to establish guidelines for preventive treatment against this occurrence. This report discusses preventive measures against rituximab-induced HBV reactivation and future objectives.
authors.affiliation: Yutaka Tsutsumi, Shinichi Ito, Hiroyuki Ohigashi, Souichi Shiratori, Department of Hematology, Hakodate Municipal Hospital, Hakodate 041-8680, Japan.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tsutsumi
authors.affiliation: Yutaka Tsutsumi, Shinichi Ito, Hiroyuki Ohigashi, Souichi Shiratori, Department of Hematology, Hakodate Municipal Hospital, Hakodate 041-8680, Japan.
authors.forename: Yoshiya
authors.initials: Y
authors.lastname: Yamamoto
authors.affiliation: Yutaka Tsutsumi, Shinichi Ito, Hiroyuki Ohigashi, Souichi Shiratori, Department of Hematology, Hakodate Municipal Hospital, Hakodate 041-8680, Japan.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Ito
authors.affiliation: Yutaka Tsutsumi, Shinichi Ito, Hiroyuki Ohigashi, Souichi Shiratori, Department of Hematology, Hakodate Municipal Hospital, Hakodate 041-8680, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ohigashi
authors.affiliation: Yutaka Tsutsumi, Shinichi Ito, Hiroyuki Ohigashi, Souichi Shiratori, Department of Hematology, Hakodate Municipal Hospital, Hakodate 041-8680, Japan.
authors.forename: Souichi
authors.initials: S
authors.lastname: Shiratori
authors.affiliation: Yutaka Tsutsumi, Shinichi Ito, Hiroyuki Ohigashi, Souichi Shiratori, Department of Hematology, Hakodate Municipal Hospital, Hakodate 041-8680, Japan.
authors.forename: Hirohito
authors.initials: H
authors.lastname: Naruse
authors.affiliation: Yutaka Tsutsumi, Shinichi Ito, Hiroyuki Ohigashi, Souichi Shiratori, Department of Hematology, Hakodate Municipal Hospital, Hakodate 041-8680, Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Teshima
keywords: Hepatitis B virus; Non-Hodgkin’s lymphoma; Nucleoside analog; Reactivation; Rituximab