title: [Insufficient use of anticoagulants in geriatric in-patients with atrial fibrillation and flutter (corrected)].
abstract: BACKGROUND
  Anticoagulation for the prevention of cardioembolic events is highly effective, but largely underused in frail older patients with atrial fibrillation or flutter (AF). This study aimed at identifying characteristics associated with anticoagulation use or non-use and the most frequent complications of this therapy.
  
  
  METHODS
  Hospitalized geriatric patients treated in a one-year interval were retrospectively studied for the presence of AF and use or non-use of anticoagulation. The risk of stroke and the indication for permanent anticoagulation were assessed using the CHA2DS2-VASc score.
  
  
  RESULTS
  In 451 of 1167 hospitalized patients (38.6%) there was a clear indication for anticoagulation. The most frequent indication for anticoagulation was AF in 381 patients (84.5% of 451 patients). Of these 381 patients, a strong indication for anticoagulation, based on CHA2DS2-VASc score, was identified in 379 patients. Of these patients, 200 (52.8%) did and 179 (47.2%) patients did not receive anticoagulation. 153 patients (40.4%) received antiplatelet therapy. 26 patients (6.7%) received neither anticoagulants nor antiplatelet therapy. The most common reason for non-implementation of anticoagulation was a high risk of falls in 93 patients (52%) of 179 patients without antocoagulation. The most frequent complications of anticoagulation were small hemorrhages without serious consequences in 8 cases. 4 patients suffered from serious bleedings.
  
  
  CONCLUSIONS
  Almost half of our geriatric population did not receive anticoagulation despite a clear indication. Antiplatelet therapy use was associated with anticoagulation non-use.
authors.affiliation: Abteilung Neuropathologie, Universitätsmedizin Göttingen.
authors.forename: M
authors.initials: M
authors.lastname: Djukic
authors.affiliation: Abteilung Neuropathologie, Universitätsmedizin Göttingen.
authors.forename: D
authors.initials: D
authors.lastname: Bergmann
authors.affiliation: Klinik für Kardiologie und Pneumologie, Universitätsmedizin Göttingen.
authors.forename: C
authors.initials: C
authors.lastname: Jacobshagen
authors.affiliation: Abteilung Neuropathologie, Universitätsmedizin Göttingen.
authors.forename: R
authors.initials: R
authors.lastname: Nau
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000150:complications* / Q000453:epidemiology; D001282:Atrial Flutter / Q000150:complications* / Q000453:epidemiology; D011307:Drug Prescriptions; D005260:Female; D006470:Hemorrhage; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology* / Q000517:prevention & control
chemical_list: D000925:Anticoagulants