title: [Microbiological profile of endophthalmitis in a referral centre in Tunisia].
abstract: OBJECTIVE
  To investigate the microbiological profile of acute postoperative endophthalmitis in a referral center in Tunisia and to assess the antibiotic sensitivity of the organisms.
  
  
  METHODS
  This is a retrospective study over a period of eleven years, conducted on patients hospitalized with acute infectious postoperative endophthalmitis. Cultures were performed on aqueous (93%) and vitreous specimens (68%) obtained at presentation. Each sample underwent direct examination, culture and antibiotic susceptibilities.
  
  
  RESULTS
  The number of acute postoperative endophthalmitis cases identified during the study period was 308. Organisms were found in 43% of samples (endophthalmitis was bacterial in 39.5%, fungal in 0.9% and polymicrobial in 2.6%). Cultures grew primarily Staphylococcus epidermidis in 31.4% of cases, Streptococcus pneumoniae in 22.7% of cases and Staphylococcus aureus in 12.7% of cases. Gram-positive cocci are more sensitive to vancomycin and Gram-negative bacilli are more susceptible to ofloxacin and ciprofloxacin.
  
  
  CONCLUSIONS
  In our study, microbiological samples were positive in 43% and coagulase-negative Gram-positive cocci are the most common organisms. However, antibiotic resistance has been increasing over the years.
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie. Electronic address: chebilahmed@yahoo.fr.
authors.forename: A
authors.initials: A
authors.lastname: Chebil
authors.affiliation: Service d'ophtalmologie A, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie.
authors.forename: O
authors.initials: O
authors.lastname: Feki
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie.
authors.forename: N
authors.initials: N
authors.lastname: Chaker
authors.affiliation: Service d'ophtalmologie A, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie.
authors.forename: I
authors.initials: I
authors.lastname: Zghal
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Hsairi
authors.affiliation: Laboratoire de microbiologie, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie.
authors.forename: N
authors.initials: N
authors.lastname: Ben Ayed
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie.
authors.forename: L
authors.initials: L
authors.lastname: Nacef
authors.affiliation: Service d'ophtalmologie B, institut Hédi-Rais d'ophtalmologie de Tunis, boulevard 9-Avril, 1006 Tunis, Tunisie.
authors.forename: L
authors.initials: L
authors.lastname: El Matri
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D009877:Endophthalmitis / Q000382:microbiology*; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D014416:Tunisia; D055815:Young Adult
keywords: Antibiotic; Antibiotiques; Endophtalmie; Endophthalmitis; Microbiologie; Microbiology; Tunisia; Tunisie