title: The Use of Cissus quadrangularis (CQR-300) in the Management of Components of Metabolic Syndrome in Overweight and Obese Participants.
abstract: We have previously reported a wide range of components from Cissus quadrangularis with in vitro effects on lipases and glycosidases. We now report that a preparation of the plant (CQR-300) administered at 300 mg daily was effective in reducing weight, as well as improving blood parameters associated with metabolic syndrome, as well as serotonin levels in obese and overweight individuals.
authors.forename: Dieudonne
authors.initials: D
authors.lastname: Kuate
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Nash
authors.forename: Barbara
authors.initials: B
authors.lastname: Bartholomew
authors.forename: Yana
authors.initials: Y
authors.lastname: Penkova
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects; D000328:Adult; D001786:Blood Glucose / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D032422:Cissus; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000188:drug therapy*; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000188:drug therapy*; D008517:Phytotherapy; D010865:Pilot Projects; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D012701:Serotonin / Q000097:blood; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference / Q000187:drug effects; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D010936:Plant Extracts; D014280:Triglycerides; D012701:Serotonin; D002784:Cholesterol