title: Analytical methods for human biomonitoring of pesticides. A review.
abstract: Biomonitoring of both currently-used and banned-persistent pesticides is a very useful tool for assessing human exposure to these chemicals. In this review, we present current approaches and recent advances in the analytical methods for determining the biomarkers of exposure to pesticides in the most commonly used specimens, such as blood, urine, and breast milk, and in emerging non-invasive matrices such as hair and meconium. We critically discuss the main applications for sample treatment, and the instrumental techniques currently used to determine the most relevant pesticide biomarkers. We finally look at the future trends in this field.
authors.affiliation: Foundation for the Promotion of the Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, Valencia, 21, Avenida Catalunya, 46020 Valencia, Spain; Public Health Laboratory of Valencia, Spain; Analytical Chemistry Department, University of Valencia, Spain. Electronic address: yusa_vic@gva.es.
authors.forename: Vicent
authors.initials: V
authors.lastname: Yusa
authors.affiliation: Institut de Chimie et Procédés pour l'Energie, l'Environnement et la Santé ICPEES UMR 7515 Groupe de Physico-Chimie de l'Atmosphère, Université de Strasbourg/CNRS, France.
authors.forename: Maurice
authors.initials: M
authors.lastname: Millet
authors.affiliation: Foundation for the Promotion of the Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, Valencia, 21, Avenida Catalunya, 46020 Valencia, Spain; Public Health Laboratory of Valencia, Spain.
authors.forename: Clara
authors.initials: C
authors.lastname: Coscolla
authors.affiliation: Foundation for the Promotion of the Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, Valencia, 21, Avenida Catalunya, 46020 Valencia, Spain; Public Health Laboratory of Valencia, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Roca
mesh_terms: D004784:Environmental Monitoring / Q000295:instrumentation / Q000379:methods*; D004785:Environmental Pollutants / Q000032:analysis / Q000097:blood* / Q000652:urine*; D006197:Hair / Q000737:chemistry; D006801:Humans; D008470:Meconium / Q000737:chemistry; D008895:Milk, Human / Q000737:chemistry; D010575:Pesticides / Q000032:analysis / Q000097:blood* / Q000652:urine*
chemical_list: D004785:Environmental Pollutants; D010575:Pesticides
keywords: Biomonitoring; Blood; Hair; Pesticides; Urine