title: Escherichia coli inner membrane protein YciB interacts with ZipA that is important for cell division.
abstract: Escherichia coli propagates by undergoing cycles of lateral elongation, septum formation, and cell fission at the mid-cell. A large number of genes involved in these processes have been identified, but it is likely that others remain. A deletion mutant of yciB (ΔyciB) is shorter in the cell length compared to wild type and, in contrast, over-expression of yciB causes elongation of the cell. Furthermore, the septum localization of ZipA, an essential protein of cell division, is disturbed in a ΔyciB mutant. Purified YciB protein directly interacted with ZipA, which might indicate that YciB is involved in the cell envelope synthesis directed by ZipA in a PBP3-independent manner.
authors.affiliation: Department of Biology, Faculty of Science, Kobe University, Rokko 1-1, Nada, Kobe 657-8501, Japan.
authors.forename: Noor Afiza
authors.initials: NA
authors.lastname: Badaluddin
authors.affiliation: Department of Biology, Faculty of Science, Kobe University, Rokko 1-1, Nada, Kobe 657-8501, Japan.
authors.forename: Madoka
authors.initials: M
authors.lastname: Kitakawa
mesh_terms: D000595:Amino Acid Sequence; D002352:Carrier Proteins / Q000235:genetics* / Q000378:metabolism*; D018797:Cell Cycle Proteins / Q000235:genetics* / Q000378:metabolism*; D002455:Cell Division / Q000502:physiology; D003598:Cytoskeletal Proteins / Q000378:metabolism; D004926:Escherichia coli / Q000166:cytology* / Q000235:genetics / Q000378:metabolism*; D029968:Escherichia coli Proteins / Q000235:genetics* / Q000378:metabolism*; D051228:Geranyltranstransferase / Q000235:genetics* / Q000378:metabolism*; D006360:Heat-Shock Proteins / Q000235:genetics / Q000378:metabolism; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D003598:Cytoskeletal Proteins; D029968:Escherichia coli Proteins; D006360:Heat-Shock Proteins; D008565:Membrane Proteins; C103795:ZipA protein, E coli; D051228:Geranyltranstransferase; C573354:IspA protein, E coli