title: High performance optical resolution with liposome immobilized hydrogel.
abstract: We prepared liposome immobilized hydrogels (LI-gels) for analysis and separation of chiral molecules, to overcome the drawbacks of liposomes such as low stability, and difficulties with handling and isolation from sample solutions. The amounts of liposomes in the hydrogels were larger than those in other solid matrices reported previously. The liposome morphology was intact, and its original properties, such as fluidity and phase transition behaviors, were preserved. We investigated the chiral recognition performance of the LI-gel, as described in our previous paper. Our results indicate that the enantioselectivity of the LI-gel was higher than those of conventional methods and of the liposomes alone. Our prepared LI-gel therefore overcomes the drawbacks of liposomes, and has potential applications in analysis and separation, including chiral separation.
authors.affiliation: Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University,1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Takaaki
authors.initials: T
authors.lastname: Ishigami
authors.affiliation: Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University,1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Sugita
authors.affiliation: Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University,1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Keishi
authors.initials: K
authors.lastname: Suga
authors.affiliation: Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University,1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Okamoto
authors.affiliation: Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University,1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan. Electronic address: B-ICE@cheng.es.osaka-u.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Umakoshi
mesh_terms: D000327:Adsorption; D020100:Hydrogels; D008081:Liposomes; D008855:Microscopy, Electron, Scanning; D055095:Optics and Photonics; D013059:Spectrum Analysis, Raman; D014364:Tryptophan / Q000737:chemistry
chemical_list: D020100:Hydrogels; D008081:Liposomes; D014364:Tryptophan
keywords: Hydrogel; Liposome; Optical resolution; Tryptophan