title: Epidemiological Scenario of Dengue in Brazil.
abstract: Dengue is the most important reemerging mosquito-borne viral disease worldwide. It is caused by any of four Dengue virus types or serotypes (DENV-1 to DENV-4) and is transmitted by mosquitoes from the genus Aedes. Ecological changes have favored the geographic expansion of the vector and, since the dengue pandemic in the Asian and Pacific regions, the infection became widely distributed worldwide, reaching Brazil in 1845. The incidence of dengue in Brazil has been frequently high, and the number of cases in the country has at some point in time represented up to 60% of the dengue reported cases worldwide. This review addresses vector distribution, dengue outbreaks, circulating serotypes and genotypes, and prevention approaches being utilized in Brazil.
authors.affiliation: United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993, USA.
authors.forename: Rafaelle C G
authors.initials: RC
authors.lastname: Fares
authors.affiliation: United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993, USA.
authors.forename: Katia P R
authors.initials: KP
authors.lastname: Souza
authors.affiliation: United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993, USA.
authors.forename: Germán
authors.initials: G
authors.lastname: Añez
authors.affiliation: United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993, USA.
authors.forename: Maria
authors.initials: M
authors.lastname: Rios
mesh_terms: D001938:Brazil / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology*; D004196:Disease Outbreaks / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence