title: The discovery of 9/8-ribbons, β/γ-peptides with curved shapes governed by a combined configuration-conformation code.
abstract: The de novo design of a β/γ-peptidic foldamer motif has led to the discovery of an unprecedented 9/8-ribbon featuring an uninterrupted alternating C9/C8 hydrogen-bonding network. The ribbons adopt partially curved topologies determined synchronistically by the β-residue configuration and the γ-residue conformation sets.
authors.affiliation: CP3A Organic Synthesis Group, ICMMO-UMR 8182, Université Paris-Sud, Université Paris-Saclay, 15 Rue Georges Clemenceau, 91405 Orsay cedex, France. david.aitken@u-psud.fr.
authors.forename: Claire M
authors.initials: CM
authors.lastname: Grison
authors.affiliation: CP3A Organic Synthesis Group, ICMMO-UMR 8182, Université Paris-Sud, Université Paris-Saclay, 15 Rue Georges Clemenceau, 91405 Orsay cedex, France. david.aitken@u-psud.fr and Université Paris Descartes, UFR Sciences Pharmaceutiques et Biologiques, 4 Avenue de l'Observatoire, 75270 Paris cedex 06, France.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Robin
authors.affiliation: CP3A Organic Synthesis Group, ICMMO-UMR 8182, Université Paris-Sud, Université Paris-Saclay, 15 Rue Georges Clemenceau, 91405 Orsay cedex, France. david.aitken@u-psud.fr.
authors.forename: David J
authors.initials: DJ
authors.lastname: Aitken
mesh_terms: D006860:Hydrogen Bonding; D008958:Models, Molecular; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary
chemical_list: D010455:Peptides