title: Genetic and phylogenetic analysis of a new porcine circovirus type 2 (PCV2) strain in China.
abstract: Porcine circovirus type 2 (PCV2) is the etiological agent associated with several pig diseases that are collectively referred to as porcine circovirus-associated disease (PCVAD). Unfortunately, PCV2 has had a serious economic impact on the swine industry. In this study, we report the genome sequence of a novel PCV2 isolate (JS2015) identified in pigs in Jiang Su, China. The complete DNA sequence was 1766 nucleotides long with an A+T content of 52.7%. It lacked a guanine (G) at nucleotide position 1045 compared to other reference PCV2 strains with a sequence length of 1766 nucleotides. Genetic characterization and phylogenetic analysis showed that the isolate JS2015 was most closely related to members of the PCV2d (AY181946) lineage. Our data provide insight into the epidemiology of porcine circovirus and may facilitate further study of the origin and evolution of PCV2.
authors.affiliation: Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture, National Center for Engineering Research of Veterinary Bio-products, Nanjing, 210000, China. 807156197@qq.com.
authors.forename: Dan
authors.identifier: http://orcid.org/0000-0002-0738-7143
authors.initials: D
authors.lastname: Zhang
authors.affiliation: Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture, National Center for Engineering Research of Veterinary Bio-products, Nanjing, 210000, China. kwh2003@yeah.net.
authors.forename: Kongwang
authors.initials: K
authors.lastname: He
authors.affiliation: Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Key Laboratory of Veterinary Biological Engineering and Technology, Ministry of Agriculture, National Center for Engineering Research of Veterinary Bio-products, Nanjing, 210000, China. wlbwh@hotmail.com.
authors.forename: Libin
authors.initials: L
authors.lastname: Wen
authors.affiliation: College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China. fhj@njau.edu.cn.
authors.forename: Hongjie
authors.initials: H
authors.lastname: Fan
mesh_terms: D000818:Animals; D001483:Base Sequence; D002681:China; D018173:Circoviridae Infections / Q000662:veterinary* / Q000821:virology; D017925:Circovirus / Q000737:chemistry / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D016679:Genome, Viral; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D013552:Swine; D013553:Swine Diseases / Q000821:virology*