title: Magnetic solid-phase extraction using carbon nanotubes as sorbents: a review.
abstract: Magnetic solid-phase extraction (M-SPE) is a procedure based on the use of magnetic sorbents for the separation and preconcentration of different organic and inorganic analytes from large sample volumes. The magnetic sorbent is added to the sample solution and the target analyte is adsorbed onto the surface of the magnetic sorbent particles (M-SPs). Analyte-M-SPs are separated from the sample solution by applying an external magnetic field and, after elution with the appropriate solvent, the recovered analyte is analyzed. This approach has several advantages over traditional solid phase extraction as it avoids time-consuming and tedious on-column SPE procedures and it provides a rapid and simple analyte separation that avoids the need for centrifugation or filtration steps. As a consequence, in the past few years a great deal of research has been focused on M-SPE, including the development of new sorbents and novel automation strategies. In recent years, the use of magnetic carbon nanotubes (M-CNTs) as a sorption substrate in M-SPE has become an active area of research. These materials have exceptional mechanical, electrical, optical and magnetic properties and they also have an extremely large surface area and varied possibilities for functionalization. This review covers the synthesis of M-CNTs and the different approaches for the use of these compounds in M-SPE. The performance, general characteristics and applications of M-SPE based on magnetic carbon nanotubes for organic and inorganic analysis have been evaluated on the basis of more than 110 references. Finally, some important challenges with respect the use of magnetic carbon nanotubes in M-SPE are discussed.
authors.affiliation: Universidad de Santiago de Compostela, Dpto. Química Analítica, Nutrición y Bromatología, Facultad de Ciencias, Alfonso X el Sabio s/n, 27002 Lugo, Spain. Electronic address: carlos.herrero@usc.es.
authors.forename: C
authors.initials: C
authors.lastname: Herrero-Latorre
authors.affiliation: Universidad de Santiago de Compostela, Dpto. Química Analítica, Nutrición y Bromatología, Facultad de Ciencias, Alfonso X el Sabio s/n, 27002 Lugo, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Barciela-García
authors.affiliation: Universidad de Santiago de Compostela, Dpto. Química Analítica, Nutrición y Bromatología, Facultad de Ciencias, Alfonso X el Sabio s/n, 27002 Lugo, Spain.
authors.forename: S
authors.initials: S
authors.lastname: García-Martín
authors.affiliation: Universidad de Santiago de Compostela, Dpto. Química Analítica, Nutrición y Bromatología, Facultad de Ciencias, Alfonso X el Sabio s/n, 27002 Lugo, Spain.
authors.forename: R M
authors.initials: RM
authors.lastname: Peña-Crecente
authors.affiliation: Universidad de Costa Rica, Sección de Química Analítica, Escuela de Química, San José, Costa Rica.
authors.forename: J
authors.initials: J
authors.lastname: Otárola-Jiménez
mesh_terms: D000327:Adsorption; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification; D004785:Environmental Pollutants / Q000737:chemistry / Q000302:isolation & purification; D007287:Inorganic Chemicals / Q000737:chemistry / Q000302:isolation & purification; D007477:Ions / Q000737:chemistry / Q000302:isolation & purification; D008280:Magnetics; D037742:Nanotubes, Carbon / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000737:chemistry / Q000302:isolation & purification; D052616:Solid Phase Extraction
chemical_list: D001688:Biological Products; D004785:Environmental Pollutants; D007287:Inorganic Chemicals; D007477:Ions; D037742:Nanotubes, Carbon; D004364:Pharmaceutical Preparations
keywords: Applications; Carbon nanotubes; Magnetic solid-phase extraction; Synthesis