title: Targeting the Achilles' heel of adult living donor liver transplant: Corner-sparing sutures with mucosal eversion technique of biliary anastomosis.
abstract: Biliary complications are regarded as the Achilles' heel of liver transplantation, especially for living donor liver transplantation (LDLT) due to smaller, multiple ducts and difficult ductal anatomy. Overall biliary complications reported in most series are between 10% and 30%. This study describes our modified technique of biliary anastomosis and its effects on incidence of biliary complications. This was a single-center retrospective study of 148 adult LDLT recipients between December 2011 and June 2014. Group 1 (n = 40) consisted of the first 40 patients for whom the standard technique of biliary anastomosis (minimal hilar dissection during donor duct division, high hilar division of the recipient bile duct, and preservation of the recipient duct periductal tissue) was used. Group 2 (n = 108) consisted of 108 patients for whom biliary anastomosis was done with the addition of corner-sparing sutures and mucosal eversion of the recipient duct to the standard technique. Primary outcome measures included biliary complications (biliary leaks and strictures). Biliary complications occurred in 7/40 patients in group 1 (17.5%) and in 4/108 patients in group 2 (3.7%). The technical factors mentioned above are aimed at preserving the blood supply of the donor and recipient ducts and hold the key for minimizing biliary complications in adult-to-adult LDLT.
authors.affiliation: Department of Liver Transplant and Hepato-Pancreato-Biliary Surgery, Fortis Hospital, Noida, India.
authors.forename: Vivek
authors.initials: V
authors.lastname: Vij
authors.affiliation: Department of Liver Transplant and Hepato-Pancreato-Biliary Surgery, Fortis Hospital, Noida, India.
authors.forename: Kausar
authors.initials: K
authors.lastname: Makki
authors.affiliation: Department of Liver Transplant and Hepato-Pancreato-Biliary Surgery, Fortis Hospital, Noida, India.
authors.forename: Vishal Kumar
authors.initials: VK
authors.lastname: Chorasiya
authors.affiliation: Department of Liver Transplant and Hepato-Pancreato-Biliary Surgery, Fortis Hospital, Noida, India.
authors.forename: Gaurav
authors.initials: G
authors.lastname: Sood
authors.affiliation: Department of Liver Transplant and Hepato-Pancreato-Biliary Surgery, Fortis Hospital, Noida, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Singhal
authors.affiliation: Department of Liver Transplant and Hepato-Pancreato-Biliary Surgery, Fortis Hospital, Noida, India.
authors.forename: Puneet
authors.initials: P
authors.lastname: Dargan
mesh_terms: D000328:Adult; D000714:Anastomosis, Surgical / Q000379:methods; D001660:Biliary Tract Diseases / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D001662:Biliary Tract Surgical Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013536:Suture Techniques