title: Pathophysiology of Gastroesophageal Reflux in Patients with Chronic Pulmonary Obstructive Disease Is Linked to an Increased Transdiaphragmatic Pressure Gradient and not to a Defective Esophagogastric Barrier.
authors.affiliation: Department of Surgery, Escola Paulista de Medicina, Federal University of Sao Paulo, Rua Diogo de Faria 1087 cj 301, Sao Paulo, SP, 04037-003, Brazil.
authors.forename: Leonardo M
authors.initials: LM
authors.lastname: Del Grande
authors.affiliation: Department of Surgery, Escola Paulista de Medicina, Federal University of Sao Paulo, Rua Diogo de Faria 1087 cj 301, Sao Paulo, SP, 04037-003, Brazil. herbella.dcir@epm.br.
authors.forename: Fernando A M
authors.initials: FA
authors.lastname: Herbella
authors.affiliation: Department of Medicine, Respiratory Division, Escola Paulista de Medicina, Federal University of Sao Paulo, Sao Paulo, Brazil.
authors.forename: Amilcar M
authors.initials: AM
authors.lastname: Bigatao
authors.affiliation: Department of Surgery, Escola Paulista de Medicina, Federal University of Sao Paulo, Rua Diogo de Faria 1087 cj 301, Sao Paulo, SP, 04037-003, Brazil.
authors.forename: Henrique
authors.initials: H
authors.lastname: Abrao
authors.affiliation: Department of Medicine, Respiratory Division, Escola Paulista de Medicina, Federal University of Sao Paulo, Sao Paulo, Brazil.
authors.forename: Jose R
authors.initials: JR
authors.lastname: Jardim
authors.affiliation: Department of Surgery, Pritzker School of Medicine, University of Chicago, Chicago, USA.
authors.forename: Marco G
authors.initials: MG
authors.lastname: Patti
keywords: Chronic obstructive pulmonary disease; Esophageal pH monitoring; Gastroesophageal reflux; High-resolution esophageal manometry