title: Synthesis of 2,5-Dihydrofurans via a Gold(I)-Catalyzed Formal [4 + 1] Cycloaddition of α-Diazoesters and Propargyl Alcohols.
abstract: A gold(I)-catalyzed formal [4 + 1] cycloaddition of α-diazoesters and propargyl alcohols is disclosed, offering access to a variety of 2,5-dihydrofurans. The reaction shows a broad substrate scope and functional group tolerance. Preliminary mechanistic investigation indicates that this reaction most likely occurs through a 5-endo-dig cyclization of an α-hydroxy allene intermediate.
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University , No.620 West Chang'an Avenue, Xi'an 710119, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University , No.620 West Chang'an Avenue, Xi'an 710119, China.
authors.forename: Xinbo
authors.initials: X
authors.lastname: Yao
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University , No.620 West Chang'an Avenue, Xi'an 710119, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University , No.620 West Chang'an Avenue, Xi'an 710119, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Han
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University , No.620 West Chang'an Avenue, Xi'an 710119, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University , No.620 West Chang'an Avenue, Xi'an 710119, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University , No.620 West Chang'an Avenue, Xi'an 710119, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University , No.620 West Chang'an Avenue, Xi'an 710119, China.
authors.forename: Zunting
authors.initials: Z
authors.lastname: Zhang