title: Total mastectomy and chest reconstruction for a rapidly progressing giant phyllodes tumor with skin necrosis: a case report.
abstract: Phyllodes tumors are rare fibroepithelial neoplasms of the breast. In the literature, borderline or malignant tumors have been reported to present with unusual characteristics including a short clinical history and extremely rapid tumor growth. Skin necrosis and infection sometimes accompanies these malignancies. Giant phyllodes tumors have a good prognosis when treated with total mastectomy, but reconstruction of the chest wall has been a challenge because of the need for a wide-range excision. We report a case of a malignant phyllodes tumor that was initially diagnosed as borderline because sudden growth of the tumor contrarily induced sparse to moderate stroma cellularity in the sections of the tumor that were biopsied. Total mastectomy without axillary lymph node resection and chest wall reconstruction using a full-thickness mesh skin graft was performed. The patient has remained free from infection and recurrence for over a year since diagnosis.
authors.affiliation: Department of Surgery, Keiyu Hospital, 3-7-3 Minatomirai Nishiku, Yokohama, 220-8521 Japan.
authors.forename: Aya
authors.initials: A
authors.lastname: Banno
authors.affiliation: Department of Surgery, Keiyu Hospital, 3-7-3 Minatomirai Nishiku, Yokohama, 220-8521 Japan.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Shimada
authors.affiliation: Department of Surgery, Keiyu Hospital, 3-7-3 Minatomirai Nishiku, Yokohama, 220-8521 Japan.
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Aga
authors.affiliation: Department of Surgery, Keiyu Hospital, 3-7-3 Minatomirai Nishiku, Yokohama, 220-8521 Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Harada
authors.affiliation: Department of Surgery, Keiyu Hospital, 3-7-3 Minatomirai Nishiku, Yokohama, 220-8521 Japan.
authors.forename: Takuji
authors.initials: T
authors.lastname: Kaburagi
authors.affiliation: Department of Surgery, Keiyu Hospital, 3-7-3 Minatomirai Nishiku, Yokohama, 220-8521 Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Seki
authors.affiliation: Department of Surgery, Keiyu Hospital, 3-7-3 Minatomirai Nishiku, Yokohama, 220-8521 Japan.
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Yasui
authors.affiliation: Department of Surgery, Keiyu Hospital, 3-7-3 Minatomirai Nishiku, Yokohama, 220-8521 Japan.
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Matsumoto
keywords: Mastectomy; Phyllodes tumor; Skin necrosis