title: Characterisation of a multidrug-resistant meningitic Escherichia coli strain (O75:K1:H5) isolated from an infant that is sensitive to memantine, a newly identified host-directed antimicrobial drug.
authors.affiliation: Department of Children's Medical Laboratory Diagnosis Center, Qilu Children's Hospital of Shandong University, Jinan 250022, China.
authors.forename: Shifu
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, China.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: He
authors.affiliation: Department of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, China.
authors.forename: Jing-Yi
authors.initials: JY
authors.lastname: Yu
authors.affiliation: Laboratory of Applied Pharmacokinetics and Bioinformatics Saban Research Institute of Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, 4650 Sunset Blvd, Mailstop #51, Los Angeles, CA 90027, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Neely
authors.affiliation: Department of Children's Medical Laboratory Diagnosis Center, Qilu Children's Hospital of Shandong University, Jinan 250022, China.
authors.forename: Lehai
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Clinical Laboratory, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Peng
authors.affiliation: Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China.
authors.forename: Xiaolu
authors.initials: X
authors.lastname: Shi
authors.affiliation: Shandong Center for Disease Control and Prevention, Jinan 250010, China.
authors.forename: Xinpeng
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Children's Medical Laboratory Diagnosis Center, Qilu Children's Hospital of Shandong University, Jinan 250022, China.
authors.forename: Sulan
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Cao
authors.affiliation: Department of Children's Research Center, Qilu Children's Hospital of Shandong University, Jinan 250022, China. Electronic address: gaizhongtao@vip.sina.com.
authors.forename: Zhongtao
authors.initials: Z
authors.lastname: Gai
authors.affiliation: Saban Research Institute of Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, 4650 Sunset Blvd, Mailstop #51, Los Angeles, CA 90027, USA. Electronic address: shuang@chla.usc.edu.
authors.forename: Sheng-He
authors.initials: SH
authors.lastname: Huang
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000942:Antigens, Bacterial / Q000032:analysis; D000954:Antigens, Surface / Q000032:analysis; D002478:Cells, Cultured; D024901:Drug Resistance, Multiple, Bacterial; D004705:Endocytosis / Q000187:drug effects; D042783:Endothelial Cells / Q000187:drug effects / Q000382:microbiology; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D008559:Memantine / Q000494:pharmacology*; D020814:Meningitis, Escherichia coli / Q000382:microbiology*; D019081:O Antigens / Q000032:analysis; D065288:Serogroup
chemical_list: D000900:Anti-Bacterial Agents; D000942:Antigens, Bacterial; D000954:Antigens, Surface; C022863:H antigen; C030659:K antigens; D019081:O Antigens; D008559:Memantine