title: Rejection sensitivity and symptom severity in patients with borderline personality disorder: effects of childhood maltreatment and self-esteem.
abstract: BACKGROUND
  Interpersonal dysfunction in Borderline Personality Disorder (BPD) is characterized by an 'anxious preoccupation with real or imagined abandonment' (DSM-5). This symptom description bears a close resemblance to that of rejection sensitivity, a cognitive affective disposition that affects perceptions, emotions and behavior in the context of social rejection. The present study investigates the level of rejection sensitivity in acute and remitted BPD patients and its relation to BPD symptom severity, childhood maltreatment, and self-esteem.
  
  
  METHODS
  Data were obtained from 167 female subjects: 77 with acute BPD, 15 with remitted BPD, and 75 healthy controls who were matched with the patients for age and education. The instruments used for assessment were the Rejection Sensitivity Questionnaire, the short version of the Borderline Symptom List, the Childhood Trauma Questionnaire, and the Rosenberg Self-Esteem Scale.
  
  
  RESULTS
  Both acute and remitted BPD patients had higher scores on the Rejection Sensitivity Questionnaire than did healthy controls. Lower self-esteem was found to be positively correlated with both increased BPD symptom severity and higher rejection sensitivity, and mediated the relation between the two. History of childhood maltreatment did not correlate with rejection sensitivity, BPD symptom severity, or self-esteem.
  
  
  CONCLUSIONS
  Our findings support the hypothesis that rejection sensitivity is an important component in BPD, even for remitted BPD patients. Level of self-esteem appears to be a relevant factor in the relationship between rejection sensitivity and BPD symptom severity. Therapeutic interventions for BPD would do well to target rejection sensitivity.
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim/Heidelberg University, Germany, PO Box 12 21 20, 68072 Mannheim, Germany.
authors.forename: Melanie
authors.initials: M
authors.lastname: Bungert
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim/Heidelberg University, Germany, PO Box 12 21 20, 68072 Mannheim, Germany.
authors.forename: Lisa
authors.initials: L
authors.lastname: Liebke
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim/Heidelberg University, Germany, PO Box 12 21 20, 68072 Mannheim, Germany.
authors.forename: Janine
authors.initials: J
authors.lastname: Thome
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim/Heidelberg University, Germany, PO Box 12 21 20, 68072 Mannheim, Germany.
authors.forename: Katrin
authors.initials: K
authors.lastname: Haeussler
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim/Heidelberg University, Germany, PO Box 12 21 20, 68072 Mannheim, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Bohus
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim/Heidelberg University, Germany, PO Box 12 21 20, 68072 Mannheim, Germany.
authors.forename: Stefanie
authors.initials: S
authors.lastname: Lis
keywords: Aggression; Anxiety; Borderline personality disorder; Childhood maltreatment; Rejection sensitivity; Self-esteem