title: An induction heating device using planar coil with high amplitude alternating magnetic fields for magnetic hyperthermia.
abstract: BACKGROUND
  Induction heating devices using the induction coil and magnetic nanoparticles (MNPs) are the way that the magnetic hyperthermia is heading.
  
  
  OBJECTIVE
  To facilitate the induction heating of in vivo magnetic nanoparticles in hyperthermia experiments on large animals.
  
  
  METHODS
  An induction heating device using a planar coil was designed with a magnetic field frequency of 328 kHz. The coil's magnetic field distribution and the device's induction heating performance on different concentrations of magnetic nanoparticles were measured.
  
  
  RESULTS
  The alternating magnetic field produced in the axis position 165 mm away from the coil center is 40 Gs in amplitude; magnetic nanoparticles with a concentration higher than 80 mg. mL-1 can be heated up rapidly.
  
  
  CONCLUSIONS
  Our results demonstrate that the device can be applied not only to in vitro and in small animal experiments of magnetic hyperthermia using MNPs, but also in large animal experiments.
authors.forename: Zuhe
authors.initials: Z
authors.lastname: Wu
authors.forename: Zihang
authors.initials: Z
authors.lastname: Zhuo
authors.forename: Dongyang
authors.initials: D
authors.lastname: Cai
authors.forename: Jian'an
authors.initials: J
authors.lastname: Wu
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Jintian
authors.initials: J
authors.lastname: Tang
mesh_terms: D000818:Animals; D006361:Heating / Q000295:instrumentation*; D006979:Hyperthermia, Induced / Q000379:methods*; D055909:Magnetic Field Therapy / Q000379:methods*; D053758:Nanoparticles
keywords: Magnetic hyperthermia; induction heating; magnetic nanoparticles; planar coil; power abortion