title: Cerebral venous thrombosis following spinal surgery in a patient with Factor V Leiden mutation.
abstract: Cerebral venous thrombosis is a devastating event leading to high mortality and morbidity rates. We present a case of cerebral venous thrombosis that occurred following spinal surgery in a patient with Factor V Leiden mutation and G1691A heterozygosity. Possible prevention and treatment strategies have been discussed.
authors.affiliation: a Bahçeşehir University Medical Faculty , Department of Neurosurgery , Istanbul , Turkey.
authors.forename: Baran
authors.initials: B
authors.lastname: Yılmaz
authors.affiliation: b University of California at San Francisco , Department of Orthopedic Surgery-Spine Center , California , USA.
authors.forename: Murat Şakir
authors.initials: MŞ
authors.lastname: Ekşi
authors.affiliation: a Bahçeşehir University Medical Faculty , Department of Neurosurgery , Istanbul , Turkey.
authors.forename: Akın
authors.initials: A
authors.lastname: Akakın
authors.affiliation: a Bahçeşehir University Medical Faculty , Department of Neurosurgery , Istanbul , Turkey.
authors.forename: Zafer Orkun
authors.initials: ZO
authors.lastname: Toktaş
authors.affiliation: c Bahçeşehir University Medical Faculty , Department of Radiology , Istanbul , Turkey.
authors.forename: Mustafa Kemal
authors.initials: MK
authors.lastname: Demir
authors.affiliation: a Bahçeşehir University Medical Faculty , Department of Neurosurgery , Istanbul , Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Konya
mesh_terms: D005165:Factor V / Q000235:genetics*; D005260:Female; D006579:Heterozygote; D006801:Humans; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000235:genetics / Q000601:surgery*; D008875:Middle Aged; D009154:Mutation / Q000235:genetics*; D012307:Risk Factors; D019851:Thrombophilia / Q000175:diagnosis / Q000235:genetics / Q000601:surgery*; D020246:Venous Thrombosis / Q000175:diagnosis / Q000235:genetics / Q000601:surgery*
chemical_list: C095381:factor V Leiden; D005165:Factor V
keywords: Factor V Leiden mutation; Factor Xa inhibitors; cerebral venous thrombosis; computed tomography; magnetic resonance venography