title: First Synthesis of 1,4-Dimethoxy-2-Naphthoxyacetic acid.
abstract: 2-Acetyl-1-hydroxynaphthalene was converted into 1,4-dimethoxy-2-naphthoxyacetic acid in seven steps (methylation, Bayer-Villiger oxidation, hydrolysis, bromination, methylation, alkylation and hydrolysis). 2-Hydroxy-1,4-naphthoquinone on acetylation, aromatization, methylation and hydrolysis, respectively, also yielded the title compound.
authors.forename: Kimberly
authors.initials: K
authors.lastname: Chinea
authors.forename: Ajoy K
authors.initials: AK
authors.lastname: Banerjee
mesh_terms: D009280:Naphthaleneacetic Acids / Q000138:chemical synthesis*; D009285:Naphthoquinones / Q000737:chemistry*
chemical_list: C000602615:1,4-dimethoxy-2-naphthoxyacetic acid; D009280:Naphthaleneacetic Acids; D009285:Naphthoquinones; C000602616:2-acetyl-1-hydroxynaphthalene; C005090:lawsone