title: Gestational diabetes among Saudi women: prevalence, risk factors and pregnancy outcomes.
abstract: OBJECTIVE
  The prevalence of gestational diabetes (GDM) has increased recently worldwide, mainly due to adoption of the International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria. The objectives of this study were to determine the prevalence of GDM in Saudi women and to assess risk factors and pregnancy outcomes using the IADPSG criteria.
  
  
  METHODS
  A prospective descriptive study of pregnant Saudi women presenting at the Maternity and Children Hospital, Medina, Saudi Arabia, between October 2011 and June 2014.
  
  
  METHODS
  Fasting plasma glucose, glycated hemoglobin, and random plasma glucose concentrations were obtained for all participants at the first antenatal visit. In women with normal results, screening for GDM was performed at 24 to 28 weeks of gestation, with a 75-g oral glucose tolerance test (OGTT). Women who had GDM were treated with diet, exercise, and insulin as needed. Pregnancy outcomes were recorded after delivery. Multiple logistic regression was used to assess possible risk factors for GDM.
  
  
  RESULTS
  Early screenings showed abnormal glucose in 211 of 954 women (22.1%). In 445 women, the OGTT showed GDM in 183 women (39.4%). GDM cases identified by OGTT and by early screening increased the rate of GDM to 51% (292 women). Older maternal age, higher body mass index, higher blood pressure, past GDM, history of delivering a malformed child, and family history of diabetes were the main risk factors for GDM. GDM increased the risk of neonatal hypoglycemia (OR 9.353), low Apgar score (OR 5.546), and induction of labor (OR 2.33). The newborns of GDM mothers had a higher birth weight: 3043 g vs. 2890 g in the non-GDM group (P=.004). Other maternal and neonatal outcomes were not significantly different between the two groups.
  
  
  CONCLUSIONS
  The prevalence of GDM is high among Saudi women. Timely and effective treatment reduces perinatal morbidity and improves outcomes.
authors.affiliation: Dr. Eman Alfadhli, Department of Medicine,, Taibha University,, PO Box 420 Madinah, Saudi Arabia, T: 966-44-844-3195 F: 966-44-844-3195, alfadhli2005@yahoo.com.
authors.forename: Eman Mohammed
authors.initials: EM
authors.lastname: Alfadhli
authors.forename: Eman Naguib
authors.initials: EN
authors.lastname: Osman
authors.forename: Taghreed Hamza
authors.initials: TH
authors.lastname: Basri
authors.forename: Nazneen Sameer
authors.initials: NS
authors.lastname: Mansuri
authors.forename: Magda Hassanein
authors.initials: MH
authors.lastname: Youssef
authors.forename: Somayah Ahmed
authors.initials: SA
authors.lastname: Assaaedi
authors.forename: Bushra Awad
authors.initials: BA
authors.lastname: Aljohani
mesh_terms: D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D015992:Body Mass Index; D016640:Diabetes, Gestational / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy; D005215:Fasting / Q000097:blood; D005260:Female; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007003:Hypoglycemia / Q000453:epidemiology / Q000209:etiology; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology / Q000209:etiology; D016015:Logistic Models; D008423:Maternal Age; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D011295:Prenatal Care; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012529:Saudi Arabia / Q000453:epidemiology; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human