title: [On the Role of Titin Phosphorylation in Development of Muscular Atrophy].
abstract: From our earlier experiments on the study of changes in titin content and the level of its phosphorylation in skeletal muscles, atrophied during space flight, hibernation, and also because of the development of alcohol-induced lesions it has been suggested that an increase in the degree of titin phosphorylation results in increased proteolytic degradation of this protein, that contributes to the development of skeletal muscle atrophy.
authors.forename: N N
authors.initials: NN
authors.lastname: Salmov
authors.forename: Yu V
authors.initials: YV
authors.lastname: Gritsyna
authors.forename: A D
authors.initials: AD
authors.lastname: Ulanova
authors.forename: I M
authors.initials: IM
authors.lastname: Vikhlyantsev
authors.forename: Z A
authors.initials: ZA
authors.lastname: Podlubnaya
mesh_terms: D000818:Animals; D064211:Connectin / Q000235:genetics / Q000378:metabolism*; D000431:Ethanol; D015870:Gene Expression; D006605:Hibernation / Q000502:physiology; D006801:Humans; D051379:Mice; D009133:Muscular Atrophy / Q000139:chemically induced / Q000209:etiology* / Q000378:metabolism* / Q000473:pathology; D010766:Phosphorylation; D020033:Protein Isoforms / Q000235:genetics / Q000378:metabolism; D055550:Protein Stability; D059748:Proteolysis; D051381:Rats; D012589:Sciuridae; D013026:Space Flight; D014893:Weightlessness / Q000009:adverse effects*
chemical_list: D064211:Connectin; D020033:Protein Isoforms; D000431:Ethanol