title: Perioperative trends in plasma colloid osmotic pressure in horses undergoing surgery.
abstract: OBJECTIVE
  To compare perioperative trends in plasma colloid osmotic pressure (COP) between horses undergoing orthopedic and colic surgery.
  
  
  METHODS
  Prospective clinical study September 2009-January 2011.
  
  
  METHODS
  Veterinary university teaching hospital.
  
  
  METHODS
  Thirty-three healthy, client-owned horses presenting for orthopedic surgery (non-GI) and 85 client-owned horses presenting for emergency exploratory celiotomy (GI, gastrointestinal).
  
  
  METHODS
  None.
  
  
  METHODS
  Data relating to the horse's parameters on presentation, surgical lesion, post-operative management and survival were extracted from computerized clinical records. Heparinized blood samples were taken on presentation (PreOp, pre-operative), on recovery from anesthesia (T0), at 12 (T12) and 24 (T24) hours post recovery. COP was measured within 4 hours of collection.
  
  
  RESULTS
  There was no significant difference in PreOp or T0 COP between groups. Both groups had a significant decrease in COP during anesthesia. When compared to their respective pre-operative values, horses in the non-GI group had significantly increased COP at T12, whereas those in the GI group had significantly reduced COP. This trend was continued at T24. Horses in the GI group placed on intravenous crystalloid isotonic fluids post-operatively had a significantly lower COP at T12 and T24. Horses in the GI group that did not survive had significantly lower post-operative COP values at T24.
  
  
  CONCLUSIONS
  Horses undergoing exploratory celiotomy had significantly lower COP post-operatively than those horses undergoing orthopedic surgery. This difference was more marked in those horses receiving isotonic crystalloid intravenous fluid therapy post-operatively and in those that did not survive to discharge. In the non-GI group an increase in COP post-operatively was common.
authors.affiliation: Philip Leverhulme Equine Hospital, University of Liverpool, Neston, CH64 7TE, UK.
authors.forename: Alexandra G
authors.initials: AG
authors.lastname: Raftery
authors.affiliation: Philip Leverhulme Equine Hospital, University of Liverpool, Neston, CH64 7TE, UK.
authors.forename: Ruth A
authors.initials: RA
authors.lastname: Morgan
authors.affiliation: Philip Leverhulme Equine Hospital, University of Liverpool, Neston, CH64 7TE, UK.
authors.forename: Paul D
authors.initials: PD
authors.lastname: MacFarlane
mesh_terms: D000758:Anesthesia / Q000662:veterinary; D000818:Animals; D003085:Colic / Q000601:surgery / Q000662:veterinary; D003102:Colloids / Q000378:metabolism*; D013505:Digestive System Surgical Procedures / Q000662:veterinary*; D006734:Horse Diseases / Q000601:surgery*; D006736:Horses; D009985:Orthopedics / Q000662:veterinary*; D009997:Osmotic Pressure / Q000502:physiology*; D011184:Postoperative Period; D011446:Prospective Studies
chemical_list: D003102:Colloids
keywords: anesthesia; colic; equine; plasma colloid osmotic pressure