title: Gold(I)-Catalyzed Addition of Silylacetylenes to Acylsilanes: Synthesis of Indanones by C-H Functionalization through a Gold(I) Carbenoid.
abstract: A gold(I)-catalyzed synthesis of indanones from trimethylsilylacetylenes and acylsilanes is presented. The reaction is initiated through a synergistic acylsilane activation-gold acetylide formation and involves consecutive alkyne σ-gold(I) addition, π-activation, and 1,2-migration of a silyl group. Studies performed on the reaction mechanism allowed to establish the nature of the silyl migrating group and invoke the participation of a gold(I) carbenoid intermediate. The reaction is completed by a gold(I) C-H functionalization step.
authors.affiliation: Instituto Universitario de Química Organometálica "Enrique Moles" and Departamento de Química Orgánica e Inorgánica, Universidad de Oviedo, c/Julián Clavería 8, 33007 Oviedo (Spain).
authors.forename: Jairo
authors.initials: J
authors.lastname: González
authors.affiliation: Instituto Universitario de Química Organometálica "Enrique Moles" and Departamento de Química Orgánica e Inorgánica, Universidad de Oviedo, c/Julián Clavería 8, 33007 Oviedo (Spain).
authors.forename: Javier
authors.initials: J
authors.lastname: Santamaría
authors.affiliation: Instituto Universitario de Química Organometálica "Enrique Moles" and Departamento de Química Orgánica e Inorgánica, Universidad de Oviedo, c/Julián Clavería 8, 33007 Oviedo (Spain). abg@uniovi.es.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Ballesteros
keywords: acylsilanes; alkynes; carbenoids; gold; homogeneous catalysis