title: Constituents of Bulbs of three Species of the Hyacinthaceae (Hyacinthoideae): Eucomis vandermerwei, E. zambesiaca and Resnova humifusa.
abstract: Phytochemical analyses of the bulbs of Eucomis vandermerwei and E. zambesiaca yielded homoisoflavonoids and triterpenoid derivatives. A new (17S*23S*)-epoxy-3β,15β,29-trihydroxy-27-norlanost-8-en-24-one) was isolated from E. zambesiaca. Resnova humifusa yielded homoisoflavonoids, and a tetrahydropyran derivative, 2-methyl-3-(4S*,5R *,7S*-trihydroxy-8S*-hydroxymethyltetrahydro-6H-4-pyranyl)-2-propenoic acid. All compounds were assayed for COX-2 inhibition of cyclooxygenase; 3,5,7-trihydroxy-3-(4'-methoxybenzyl)-4-chromanone was found to have significant activity.
authors.forename: Jaspreet K
authors.initials: JK
authors.lastname: Sihra
authors.forename: Alfred E
authors.initials: AE
authors.lastname: Thumser
authors.forename: Moses K
authors.initials: MK
authors.lastname: Langat
authors.forename: Neil R
authors.initials: NR
authors.lastname: Crouch
authors.forename: Dulcie A
authors.initials: DA
authors.lastname: Mulholland
mesh_terms: D019668:Liliaceae / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D014315:Triterpenes; C000602611:epoxy-3beta,15beta,29-trihydroxy-27-norlanost-8-en-24-one