title: Biocompatibility and characterization of polylactic acid/styrene-ethylene-butylene-styrene composites.
abstract: Polylactic acid (PLA)/styrene-ethylene-butylene-styrene (SEBS) composites were prepared by melt blending. Differential scanning calorimetry (DSC) and wide angle X-ray diffraction (WXRD) were used to characterize PLA and PLA/SEBS composites in terms of their melting behavior and crystallization. Curves from thermal gravimetric analysis (TGA) illustrated that thermostability increased with SEBS content. Further morphological analysis of PLA/SEBS composites revealed that SEBS molecules were not miscible with PLA molecules in PLA/SEBS composites. The tensile testing for PLA and PLA/SEBS composites showed that the elongation at the break was enhanced, but tensile strength decreased with increasing SEBS content. L929 fibroblast cells were chosen to assess the cytocompatibility; the cell growth of PLA was found to decrease with increasing SEBS content. This study proposes possible reasons for these properties of PLA/SEBS composites.
authors.affiliation: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.|R&D Center for Membrane Technology, Department of Chemical Engineering, Chung Yuan University, Jhongli 32023, Taiwan.|Department of Materials and Textiles, Oriental Institute of Technology, Pan-Chiao 22064, Taiwan.
authors.forename: Chi-Hui
authors.initials: CH
authors.lastname: Tsou
authors.affiliation: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
authors.forename: Bo-Jyue
authors.initials: BJ
authors.lastname: Kao
authors.affiliation: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
authors.forename: Ming-Chien
authors.initials: MC
authors.lastname: Yang
authors.affiliation: Department of Creative Fashion Design, Taoyuan Innovation Institute of Technology, Jhongli 32091, Taiwan.
authors.forename: Maw-Cherng
authors.initials: MC
authors.lastname: Suen
authors.affiliation: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
authors.forename: Yi-Hsuan
authors.initials: YH
authors.lastname: Lee
authors.affiliation: Department of Materials and Textiles, Oriental Institute of Technology, Pan-Chiao 22064, Taiwan.
authors.forename: Jui-Chin
authors.initials: JC
authors.lastname: Chen
authors.affiliation: Department of Materials and Textiles, Oriental Institute of Technology, Pan-Chiao 22064, Taiwan.
authors.forename: Wei-Hua
authors.initials: WH
authors.lastname: Yao
authors.affiliation: Department of Materials and Textiles, Oriental Institute of Technology, Pan-Chiao 22064, Taiwan.
authors.forename: Shang-Ming
authors.initials: SM
authors.lastname: Lin
authors.affiliation: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
authors.forename: Chih-Yuan
authors.initials: CY
authors.lastname: Tsou
authors.affiliation: Department of Chemical and Materials Engineering, National Ilan University, I-Lan 26047, Taiwan.
authors.forename: Shu-Hsien
authors.initials: SH
authors.lastname: Huang
authors.affiliation: R&D Center for Membrane Technology, Department of Chemical Engineering, Chung Yuan University, Jhongli 32023, Taiwan.
authors.forename: Manuel
authors.initials: M
authors.lastname: De Guzman
authors.affiliation: R&D Center for Membrane Technology, Department of Chemical Engineering, Chung Yuan University, Jhongli 32023, Taiwan.
authors.forename: Wei-Song
authors.initials: WS
authors.lastname: Hung
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000633:toxicity*; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D055119:Elastic Modulus; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects / Q000502:physiology; D019344:Lactic Acid / Q000737:chemistry* / Q000633:toxicity; D008422:Materials Testing; D051379:Mice; D011090:Polyenes / Q000737:chemistry / Q000633:toxicity; D011091:Polyesters; D020959:Polyethylene / Q000737:chemistry* / Q000633:toxicity; D011108:Polymers / Q000737:chemistry* / Q000633:toxicity; D011137:Polystyrenes / Q000737:chemistry* / Q000633:toxicity; D013314:Stress, Mechanical; D013718:Tensile Strength
chemical_list: D001672:Biocompatible Materials; D011090:Polyenes; D011091:Polyesters; D011108:Polymers; D011137:Polystyrenes; D019344:Lactic Acid; C033616:poly(lactide); D020959:Polyethylene; C008952:polybutene
keywords: Polylactic acid (PLA); biocompatibility; styrene-ethylene-butylene-styrene (SEBS); tensile property