title: CRISPR/Cas: A Faster and More Efficient Gene Editing System.
abstract: Gene editing technology has been at its mature stage with the successful development of TALENs and CRISPR/Cas enzymes. The genetically modified endonucleases of ZFNs, TALENs, and CRISPR/Cas are widely used in the development of genetically modified cells or organisms. Among the enzymes that possess gene editing ability, CRISPR/Cas is the latest member with high efficiency in gene editing and simplicity in cloning. This review discusses the discovery of CRISPR, the development of the CRISPR/Cas system, and its applications as a new gene editing system.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Huifen
authors.initials: H
authors.lastname: Xu
authors.forename: Jiangfang
authors.initials: J
authors.lastname: Miao
authors.forename: Andy
authors.initials: A
authors.lastname: Zhang
authors.forename: Xiaojin
authors.initials: X
authors.lastname: Kou
authors.forename: Wen
authors.initials: W
authors.lastname: Li
authors.forename: Lin
authors.initials: L
authors.lastname: Zhou
authors.forename: Hong-Guang
authors.initials: HG
authors.lastname: Xie
authors.forename: Pierre
authors.initials: P
authors.lastname: Sirois
authors.forename: Kai
authors.initials: K
authors.lastname: Li
mesh_terms: D000818:Animals; D064112:Clustered Regularly Interspaced Short Palindromic Repeats / Q000235:genetics*; D005818:Genetic Engineering / Q000379:methods*; D006801:Humans; D036103:Nanotechnology; D013997:Time Factors