title: A brief history of the TDIF-PXY signalling module: balancing meristem identity and differentiation during vascular development.
abstract: 474 I. 474 II. 475 III. 475 IV. 477 V. 477 VI. 477 VII. 479 VIII. 481 482 References 482 SUMMARY: A significant proportion of terrestrial biomass is constituted of xylem cells that make up woody plant tissue. Xylem is required for water transport, and is present in the vascular tissue with a second conductive tissue, phloem, required primarily for nutrient transport. Both xylem and phloem are derived from cell divisions in vascular meristems known as the cambium and procambium. One major component that influences several aspects of plant vascular development, including cell division in the vascular meristem, vascular organization and differentiation of vascular cell types, is a signalling module characterized by a peptide ligand called TRACHEARY ELEMENT DIFFERENTIATION INHIBITORY FACTOR (TDIF) and its cognate receptor, PHLOEM INTERCALATED WITH XYLEM (PXY). In this review, we explore the literature that describes signalling components, phytohormones and transcription factors that interact with these two central factors, to control the varying outputs required in vascular tissues for normal organization and elaboration of plant vascular tissue.
authors.affiliation: Plant Biology and Genome Center, University of California Davis, 1 Shields Avenue, Davis, CA, 95616, USA.|School of Biological and Biomedical Sciences, Durham University, South Road, Durham, DH1 3LE, UK.
authors.forename: J Peter
authors.initials: JP
authors.lastname: Etchells
authors.affiliation: Plant Biology and Genome Center, University of California Davis, 1 Shields Avenue, Davis, CA, 95616, USA.|Laboratory of Biochemistry, Wageningen University, Dreijenlaan 3, 6703HA, Wageningen, the Netherlands.
authors.forename: Margot E
authors.initials: ME
authors.lastname: Smit
authors.affiliation: Plant Biology and Genome Center, University of California Davis, 1 Shields Avenue, Davis, CA, 95616, USA.
authors.forename: Allison
authors.initials: A
authors.lastname: Gaudinier
authors.affiliation: Plant Biology and Genome Center, University of California Davis, 1 Shields Avenue, Davis, CA, 95616, USA.
authors.forename: Clara J
authors.initials: CJ
authors.lastname: Williams
authors.affiliation: Plant Biology and Genome Center, University of California Davis, 1 Shields Avenue, Davis, CA, 95616, USA.
authors.forename: Siobhan M
authors.initials: SM
authors.lastname: Brady
mesh_terms: D029681:Arabidopsis Proteins / Q000378:metabolism*; D002454:Cell Differentiation; D018519:Meristem / Q000378:metabolism* / Q000502:physiology; D009842:Oligopeptides / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism; D063245:Plant Development / Q000502:physiology*; D010937:Plant Growth Regulators / Q000378:metabolism; D010940:Plant Proteins / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism*; D015398:Signal Transduction; D014157:Transcription Factors / Q000378:metabolism; D052584:Xylem / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D009842:Oligopeptides; D010455:Peptides; D010937:Plant Growth Regulators; D010940:Plant Proteins; D014157:Transcription Factors; C532424:tracheary element differentiation inhibitory factor, Arabidopsis; D011494:Protein Kinases; C524131:PXY protein, Arabidopsis
keywords: cambium; phloem; procambium; signalling; vascular development; xylem