title: Use of 18F-FDG PET-CT for Detection of Active Disease in Acute Myeloid Leukemia.
abstract: A 4-year-old girl with history of acute myeloid leukemia post chemotherapy and stem cell transplant presented with pancytopenia. F-FDG PET-CT (PET-CT) showed multiple metastatic bone and extra medullary soft tissue lesions. Bone marrow biopsy after additional chemotherapy was negative. Concurrent FDG PET-CT demonstrated hypermetabolic foci in the left thigh and hand consistent with residual soft tissue disease. These lesions resolved after further treatment, but a subsequent PET-CT identified a new site of biopsy-proven chloroma. This case illustrates the important role of FDG PET-CT in identifying clinically undetectable extramedullary sites of disease, which may impact subsequent clinical management.
authors.affiliation: From the *Departments of Radiology and Nuclear Medicine at the University of Washington, and †Department of Radiology at Seattle Children's Hospital, Seattle, WA.
authors.forename: Saeed
authors.initials: S
authors.lastname: Elojeimy
authors.forename: A
authors.initials: A
authors.lastname: Luana Stanescu
authors.forename: Marguerite T
authors.initials: MT
authors.lastname: Parisi
mesh_terms: D001853:Bone Marrow / Q000000981:diagnostic imaging; D002675:Child, Preschool; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000000981:diagnostic imaging*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18