title: Streptomyces metabolites in divergent microbial interactions.
abstract: Streptomyces and related bacteria produce a wide variety of secondary metabolites. Of these, many compounds have industrial applications, but the question of why this group of microorganism produces such various kinds of biologically active substances has not yet been clearly answered. Here, we overview the results from our studies on the novel function and role of Streptomyces metabolites. The diverged action of negative and positive influences onto the physiology of various microorganisms infers the occurrence of complex microbial interactions due to the effect of small molecules produced by Streptomyces. The interactions may serve as a basis for the constitution of biological community.
authors.affiliation: Life Science Research Center, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takano
authors.affiliation: Life Science Research Center, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.|Institute of Applied Biochemistry and Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nishiyama
authors.affiliation: Life Science Research Center, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.
authors.forename: Sho-ichi
authors.initials: S
authors.lastname: Amano
authors.affiliation: Life Science Research Center, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan.
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Beppu
authors.affiliation: Institute of Applied Biochemistry and Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan. kobay@agbi.tsukuba.ac.jp.
authors.forename: Michihiko
authors.initials: M
authors.lastname: Kobayashi
authors.affiliation: Life Science Research Center, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa, 252-0880, Japan. ueda.kenji@nihon-u.ac.jp.
authors.forename: Kenji
authors.initials: K
authors.lastname: Ueda
mesh_terms: D000818:Animals; D006801:Humans; D056265:Microbial Interactions; D064210:Secondary Metabolism; D013302:Streptomyces / Q000378:metabolism*
keywords: Biological interaction; Microbial community; Secondary metabolites; Streptomyces