title: [Necrotizing pneumonia due to Streptococcus pneumonia].
abstract: We present a patient with a necrotizing pneumonia due to Streptococcus pneumoniae. This complication often affects children and is relatively rare and unrecognized in adults. Its diagnosis is often difficult on chest-X-ray and need a chest computed tomography. No risk factors predisposing to necrosis are described in literature and its mortality is not different from pneumonia without necrosis. The serotype 3 is the most common type implicated in pneumococcal necrotizing pneumonia. Study of virulence factors of S. pneumoniae and various genetic polymorphisms of the host should allow a better understanding of this complication.
authors.affiliation: Laboratoire de bactériologie-virologie-hygiène, CHU Reims, Hôpital Robert Debré, Reims, France, UFR Médecine, Université Reims Champagne-Ardenne, SFR CAP Santé EA 4687, Reims, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Limelette
authors.affiliation: Laboratoire de bactériologie-virologie-hygiène, CHU Reims, Hôpital Robert Debré, Reims, France, UFR Médecine, Université Reims Champagne-Ardenne, SFR CAP Santé EA 4687, Reims, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Guillard
authors.affiliation: Service de réanimation, CHU Reims, Hôpital Maison Blanche, Reims, France.
authors.forename: Marie Laure
authors.initials: ML
authors.lastname: Boubee
authors.affiliation: Service de réanimation, CHU Reims, Hôpital Maison Blanche, Reims, France.
authors.forename: Jean Sébastien
authors.initials: JS
authors.lastname: Petit
authors.affiliation: Laboratoire de bactériologie-virologie-hygiène, CHU Reims, Hôpital Robert Debré, Reims, France, UFR Médecine, Université Reims Champagne-Ardenne, SFR CAP Santé EA 4687, Reims, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Vernet-Garnier
authors.affiliation: Laboratoire de bactériologie-virologie-hygiène, CHU Reims, Hôpital Robert Debré, Reims, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Grillon
authors.affiliation: Service de radiologie, CHU Reims, Hôpital Maison Blanche, Reims, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Toubas
authors.affiliation: Laboratoire de bactériologie-virologie-hygiène, CHU Reims, Hôpital Robert Debré, Reims, France, UFR Médecine, Université Reims Champagne-Ardenne, SFR CAP Santé EA 4687, Reims, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: De Champs
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D011018:Pneumonia, Pneumococcal / Q000473:pathology*
keywords: Streptococcus pneumoniae; necrotizing pneumonia