title: Autism Spectrum Disorders (ASD) in Blind Children: Very High Prevalence, Potentially Better Outlook.
abstract: Autism spectrum disorders affected 19 of 38 unselected children at a school for the blind in Cordoba, Argentina. Autism was linked to total congenital blindness, not blindness' etiology, acquired or incomplete blindness, sex, overt brain damage, or socioeconomic status. Autism "recovery," had occurred in 4 verbal children. Congenital blindness causes profoundly deviant sensory experience and massive reorganization of brain connectivity. Its ≥ 30 times greater prevalence than in sighted children suggests a distinct pathogenesis. Unawareness of autism's high prevalence in blind individuals includes blindness' rarity, misunderstanding of autism as "disease" rather than dimensional behavioral diagnosis, reluctance to diagnose it in blind children, and ignorance of its potentially more favorable outcome. Future investigation may suggest interventions to prevent or mitigate it.
authors.affiliation: Centro Privado de Neurología y Neuropsicología Infanto Juvenil Wernicke, Viamonte 131 B° General Paz, CP: X5004AUC, Córdoba, Argentina. rubinjurerj@gmail.com.
authors.forename: Rubin
authors.identifier: http://orcid.org/0000-0002-0366-4369
authors.initials: R
authors.lastname: Jure
authors.affiliation: UTI Hospital de Niños de la Santísima Trinidad de Córdoba; Cátedra de Informática Médica, Universidad Nacional de Córdoba, Córdoba, Argentina.
authors.forename: Ramón
authors.initials: R
authors.lastname: Pogonza
authors.affiliation: Saul R. Korey Department of Neurology, Department of Pediatrics, and Rose F. Kennedy Center for Research on Intellectual and Developmental Disability, Albert Einstein College of Medicine, Bronx, NY, USA. Isabelle.rapin@einstein.yu.edu.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Rapin
mesh_terms: D000293:Adolescent; D000067877:Autism Spectrum Disorder / Q000453:epidemiology*; D001766:Blindness / Q000151:congenital / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D006801:Humans; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
keywords: Autism recovery; Autism spectrum disorder; Autistic regression; Blindisms; Blindness; Congenital blindness