title: Superparamagnetic calcium ferrite nanoparticles synthesized using a simple sol-gel method for targeted drug delivery.
abstract: The calcium ferrite nano-particles (CaFe2O4 NPs) were synthesized using a sol-gel method for targeted drug delivery application. The proposed nano-particles were initially prepared by mixing calcium and iron nitrates that were added with citric acid in order to prevent agglomeration and subsequently calcined at a temperature of 550°C to obtain small particle size. The prepared nanoparticles were characterized by using an XRD (X-ray diffraction), which revealed the configuration of orthorhombic structures of the CaFe2O4 nano-particles. A crystallite size of ~13.59 nm was obtained using a Scherer's formula. Magnetic analysis using a VSM (Vibrating Sample Magnetometer analysis), revealed that the synthesized particles exhibited super-paramagnetic behavior having magnetization saturation of approximately 88.3emu/g. Detailed observation via the scanning electron microscopy (SEM) showed the calcium ferrite nano-particles were spherical in shape.
authors.affiliation: Department of Mechanical and Materials Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Malaysia.
authors.forename: N H
authors.initials: NH
authors.lastname: Sulaiman
authors.affiliation: Department of Mechanical and Materials Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Malaysia.|Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, 43600 Bangi, Malaysia.
authors.forename: M J
authors.initials: MJ
authors.lastname: Ghazali
authors.affiliation: Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, 43600 Bangi, Malaysia.
authors.forename: B Y
authors.initials: BY
authors.lastname: Majlis
authors.affiliation: Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, 43600 Bangi, Malaysia.
authors.forename: J
authors.initials: J
authors.lastname: Yunas
authors.affiliation: Department of Mechanical and Materials Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600 Bangi, Malaysia.|Department of Management office, Faculty of Dentistry, Universiti Kebangsaan Malaysia, 43600 Bangi, Malaysia.
authors.forename: M
authors.initials: M
authors.lastname: Razali
mesh_terms: D002118:Calcium / Q000737:chemistry*; D003911:Dextrans / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008422:Materials Testing; D058990:Molecular Targeted Therapy / Q000379:methods*; D053769:Nanocapsules / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D044367:Phase Transition
chemical_list: D003911:Dextrans; D005290:Ferric Compounds; D058185:Magnetite Nanoparticles; D053769:Nanocapsules; C097921:ferumoxtran-10; C001215:ferrite; D002118:Calcium
keywords: Magnetic nanoparticles; drug delivery; superparamagnetic