title: Disease Related Knowledge Summarization Based on Deep Graph Search.
abstract: The volume of published biomedical literature on disease related knowledge is expanding rapidly. Traditional information retrieval (IR) techniques, when applied to large databases such as PubMed, often return large, unmanageable lists of citations that do not fulfill the searcher's information needs. In this paper, we present an approach to automatically construct disease related knowledge summarization from biomedical literature. In this approach, firstly Kullback-Leibler Divergence combined with mutual information metric is used to extract disease salient information. Then deep search based on depth first search (DFS) is applied to find hidden (indirect) relations between biomedical entities. Finally random walk algorithm is exploited to filter out the weak relations. The experimental results show that our approach achieves a precision of 60% and a recall of 61% on salient information extraction for Carcinoma of bladder and outperforms the method of Combo.
authors.affiliation: College of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Wu
authors.affiliation: College of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors.forename: Zhihao
authors.initials: Z
authors.lastname: Yang
authors.affiliation: College of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors.forename: ZhiHeng
authors.initials: Z
authors.lastname: Li
authors.affiliation: College of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors.forename: Hongfei
authors.initials: H
authors.lastname: Lin
authors.affiliation: College of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D035843:Biomedical Research; D019295:Computational Biology / Q000379:methods*; D057225:Data Mining / Q000379:methods*; D016208:Databases, Factual; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods*; D051188:Knowledge Bases; D001749:Urinary Bladder Neoplasms