title: Slow-wave disruption enhances the accessibility of positive memory traces.
abstract: The purpose of this study was to explore the effects of slow-wave disruption on positive and negative word recognition in a sample of healthy control participants and those with major depressive disorder. Prior to sleep, participants learned a set of emotional and neutral words during an encoding task by responding whether or not the word described them. Following baseline sleep, participants underwent one night of selective slow-wave disruption by auditory stimuli. Accuracy and reaction time to a recognition word set, including both positive and negative words, was assessed in the morning. Repeated-measures ANOVA revealed a significant interaction between word valence and condition, with positive words recognized significantly faster than negative words after disruption, in only healthy control participants. There were no significant results in those with major depressive disorder, or with regard to accuracy. These results may add to the increasing body of literature suggesting a hedonic bias to positive stimuli following sleep disruption.
authors.affiliation: Department of Psychology, University of Michigan, 530 Church St, Ann Arbor, MI 48109, United States. Electronic address: jrgolds@umich.edu.
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Goldschmied
authors.affiliation: Department of Psychology, University of Michigan, 530 Church St, Ann Arbor, MI 48109, United States. Electronic address: chungfuc@umich.edu.
authors.forename: Philip
authors.initials: P
authors.lastname: Cheng
authors.affiliation: Department of Psychology, University of Michigan, 530 Church St, Ann Arbor, MI 48109, United States. Electronic address: hyangkim@sogang.ac.kr.
authors.forename: Hyang Sook
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Department of Psychology, University of Michigan, 530 Church St, Ann Arbor, MI 48109, United States. Electronic address: casementmd@upmc.edu.
authors.forename: Melynda
authors.initials: M
authors.lastname: Casement
authors.affiliation: Department of Psychiatry, University of Michigan, 4250 Plymouth Rd, Ann Arbor, MI 48109, United States. Electronic address: roseanne.armitage@sbcglobal.net.
authors.forename: Roseanne
authors.initials: R
authors.lastname: Armitage
authors.affiliation: Department of Psychology, University of Michigan, 530 Church St, Ann Arbor, MI 48109, United States. Electronic address: pjdeldin@umich.edu.
authors.forename: Patricia J
authors.initials: PJ
authors.lastname: Deldin
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D003865:Major Depressive Disorder / Q000503:physiopathology / Q000523:psychology*; D004644:Emotions / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D011930:Reaction Time / Q000502:physiology; D012890:Sleep / Q000502:physiology*; D055815:Young Adult
keywords: Memory; Recognition; Reward; Slow-wave