title: Surgical History of Sleep Apnea in Pediatric Patients with Chiari Type 1 Malformation.
abstract: Sleep apnea represents a relative indication for posterior fossa decompression in pediatric patients with Chiari malformation type 1. Duraplasty was associated with improvement of sleep apnea in 100% of patients and dural splitting with improvement in 50% of patients. Duraplasty and dural splitting were associated with a similar reduction in tonsillar herniation on radiographic imaging of 58% (37% excluding tonsillectomy) and 35%, respectively. Longitudinal follow-up studies of patients with either neurologic deficits or severe symptoms will further elucidate the natural history of Chiari malformation type 1 and more appropriately gauge the risk-benefit tradeoff of surgical intervention.
authors.affiliation: Department of Neurological Surgery, University of Virginia Health Science Center, 1215 Lee Street, Charlottesville, VA 22908, USA.
authors.forename: Isaac Jonathan
authors.initials: IJ
authors.lastname: Pomeraniec
authors.affiliation: Department of Neurological Surgery, University of Virginia Health Science Center, 1215 Lee Street, Charlottesville, VA 22908, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Ksendzovsky
authors.affiliation: Department of Neurological Surgery, University of Virginia Health Science Center, 1215 Lee Street, Charlottesville, VA 22908, USA.
authors.forename: Pearl L
authors.initials: PL
authors.lastname: Yu
authors.affiliation: Department of Neurological Surgery, University of Virginia Health Science Center, 1215 Lee Street, Charlottesville, VA 22908, USA. Electronic address: jaj2k@virginia.edu.
authors.forename: John A
authors.initials: JA
authors.lastname: Jane
mesh_terms: D001139:Arnold-Chiari Malformation / Q000150:complications* / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D019299:Decompression, Surgical / Q000379:methods; D004388:Dura Mater / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome
keywords: Chiari malformation; Dural splitting; Duraplasty; Sleep apnea