title: Multi-Facial, Non-Peptidic α-Helix Mimetics.
abstract: α-Helices often recognize their target proteins at protein-protein interfaces through more than one recognition face. This review describes the state-of-the-art in the design of non-peptidic α-helix mimetics that reproduce functionality from multiple faces of an α-helix.
authors.affiliation: Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine St., Baltimore, MD 21201, USA. mlanning@umaryland.edu.
authors.forename: Maryanna E
authors.initials: ME
authors.lastname: Lanning
authors.affiliation: Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 N. Pine St., Baltimore, MD 21201, USA. sfletcher@rx.umaryland.edu.|University of Maryland Greenebaum Cancer Center, 22 S. Greene St., Baltimore, MD 21201, USA. sfletcher@rx.umaryland.edu.
authors.forename: Steven
authors.initials: S
authors.lastname: Fletcher
keywords: Bak; Bcl-2; Bim; HMD2; amphipathic; cancer; p53; protein–protein interaction; proteomimetic; α-helix mimetic