title: Hydrazone-initiated carbene/alkyne cascades to form polycyclic products: ring-fused cyclopropenes as mechanistic intermediates.
abstract: A hydrazone-based carbene/alkyne cascade produced a variety of bridged and fused polycyclic products. NaOSiMe3 is a superior base for conversion of hydrazones to diazoalkanes. A key mechanistic intermediate, a ring-fused cyclopropene, has been isolated and characterized.
authors.affiliation: Department of Chemistry, University of Houston , 3585 Cullen Blvd, Room 112, Houston, Texas 77204-5003, United States.
authors.forename: Phong Q
authors.initials: PQ
authors.lastname: Le
authors.affiliation: Department of Chemistry, University of Houston , 3585 Cullen Blvd, Room 112, Houston, Texas 77204-5003, United States.
authors.forename: Jeremy A
authors.initials: JA
authors.lastname: May
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry*; D006835:Hydrazones / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D003521:Cyclopropanes; D006835:Hydrazones; D011083:Polycyclic Compounds; C030011:carbene; C021985:cyclopropene; D008697:Methane