title: Energy Migration Engineering of Bright Rare-Earth Upconversion Nanoparticles for Excitation by Light-Emitting Diodes.
abstract: A novel Nd(3+) -sensitized upconversion nanoparticle (UCNP) that can be excited by near-infrared 740 nm light-emitting diode (LED) lamps with bright upconversion luminescence is designed. Yb(3+) ion distribution is engineered to increase the energy migration efficiency. The benefit of the novel LED-excited UCNPs is demonstrated by imaging of breast cancer cells and enabling an economic handheld semiquantitative visual measurement device.
authors.affiliation: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing, 100190, China.|Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
authors.forename: Yeteng
authors.initials: Y
authors.lastname: Zhong
authors.affiliation: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing, 100190, China.
authors.forename: Iman
authors.initials: I
authors.lastname: Rostami
authors.affiliation: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing, 100190, China.
authors.forename: Zihua
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Chemistry, Stanford University, Stanford, CA, 94305, USA.
authors.forename: Hongjie
authors.initials: H
authors.lastname: Dai
authors.affiliation: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing, 100190, China.|Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing, 102206, China.|Institute for Systems Biology, 401 Terry Avenue N, Seattle, WA, 98109, USA.|Yangtze River Delta Academy of Nanotechnology and Industry Development Research, Jiaxing, Zhejiang Province, 314000, China.
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Hu
mesh_terms: D045744:Cell Line, Tumor; D004735:Energy Transfer; D005459:Fluorides / Q000737:chemistry; D057809:HEK293 Cells; D006367:HeLa Cells; D006801:Humans; D007259:Infrared Rays; D008674:Metals, Rare Earth / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism; D015018:Ytterbium / Q000737:chemistry; D015019:Yttrium / Q000737:chemistry
chemical_list: D005459:Fluorides; D008674:Metals, Rare Earth; D010455:Peptides; D018719:Erb-b2 Receptor Tyrosine Kinases; D015018:Ytterbium; D015019:Yttrium; C525362:sodium yttriumtetrafluoride; C508053:ERBB2 protein, human
keywords: energy migration; light-emitting diodes; upconversion, nanoparticles