title: Progestin therapy in endometriosis.
abstract: Progestins are synthetic compounds that mimic the effects of progesteron. For over 50 years, oral progestins have been demonstrated to be effective in the treatment of endometriosis. They were reported to reduce or eliminate pain symptoms in approximately 90% of the patients. Progestins are available in many forms, including oral preparations, injections, subdermal implants and intrauterine systems. Continuous progestin use is an effective therapy for the treatment of painful symptoms associated with endometriosis but there had been no evidence of progestin use being superior to other types of treatment in endometriosis-related pain symptoms.
authors.affiliation: Reproductive Endocrinology & Infertility Division, Cerrahpaşa School of Medicine, Obstetrics & Gynecology Department, İstanbul University, Cerrahpaşa PTT PK:31 34301 Fatih/İstanbul, Turkey.
authors.forename: Altay
authors.initials: A
authors.lastname: Gezer
authors.affiliation: Reproductive Endocrinology & Infertility Division, Cerrahpaşa School of Medicine, Obstetrics & Gynecology Department, İstanbul University, Cerrahpaşa PTT PK:31 34301 Fatih/İstanbul, Turkey.
authors.forename: Engin
authors.initials: E
authors.lastname: Oral
mesh_terms: D004343:Drug Implants; D004715:Endometriosis / Q000188:drug therapy* / Q000473:pathology; D004717:Endometrium / Q000187:drug effects; D005260:Female; D006801:Humans; D007436:Intrauterine Devices, Medicated; D017699:Pelvic Pain / Q000188:drug therapy* / Q000209:etiology; D011372:Progestins / Q000627:therapeutic use*
chemical_list: D004343:Drug Implants; D011372:Progestins
keywords: endometriosis; progesterone; progestin; therapy