title: Paper-based chemical and biological sensors: Engineering aspects.
abstract: Remarkable efforts have been dedicated to paper-based chemosensors and biosensors over the last few years, mainly driven by the promise of reaching the best trade-off between performance, affordability and simplicity. Because of the low-cost and rapid prototyping of these sensors, recent research has been focused on providing affordable diagnostic devices to the developing world. The recent progress in sensitivity, multi-functionality and integration of microfluidic paper-based analytical devices (µPADs), increasingly suggests that this technology is not only attractive in resource-limited environments but it also represents a serious challenger to silicon, glass and polymer-based biosensors. This review discusses the design, chemistry and engineering aspects of these developments, with a focus on the past few years.
authors.affiliation: Department of Bioproducts and Biosystems Engineering, University of Minnesota Twin Cities, Saint Paul, MN 55108, United States.
authors.forename: Snober
authors.initials: S
authors.lastname: Ahmed
authors.affiliation: Department of Bioproducts and Biosystems Engineering, University of Minnesota Twin Cities, Saint Paul, MN 55108, United States.
authors.forename: Minh-Phuong Ngoc
authors.initials: MP
authors.lastname: Bui
authors.affiliation: Department of Bioproducts and Biosystems Engineering, University of Minnesota Twin Cities, Saint Paul, MN 55108, United States. Electronic address: aabbas@umn.edu.
authors.forename: Abdennour
authors.initials: A
authors.lastname: Abbas
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D003217:Conductometry / Q000295:instrumentation*; D004209:Disposable Equipment; D004867:Equipment Design; D019544:Equipment Failure Analysis; D017743:Equipment Reuse; D007118:Immunoassay / Q000295:instrumentation*; D056656:Lab-On-A-Chip Devices; D010209:Paper
keywords: Biosensor; Cellulose paper; Chemosensor; Lateral flow assays; Paper microfluidics