title: [CEREBRAL MICROGLIA AND MICROGLIAL MARKERS].
abstract: In recent years, there has been a steady increase of interest in various aspects of the organization and functioning of microglia. However, the information on modern immunocytochemical methods of its identification is ambiguous and requires systematization. In the present paper. the main attention is focused on microglial markers--the proteins (Iba-1, CD11b, CD68, HLA-DR, and some others) expressed by normal microgliocytes and those activated by the effects of damaging factors. Characterization of markers and methods of microglia immunocytochemical labeling is combined with an analysis of the data concerning the origin and structural organization of microgliocytes.
authors.forename: D E
authors.initials: DE
authors.lastname: Korzhevskiy
authors.forename: O V
authors.initials: OV
authors.lastname: Kirik
mesh_terms: D000818:Animals; D015703:Antigens, CD / Q000378:metabolism*; D015214:Antigens, Differentiation, Myelomonocytic / Q000378:metabolism*; D015415:Biomarkers / Q000378:metabolism; D039481:CD11b Antigen / Q000378:metabolism; D002135:Calcium-Binding Proteins / Q000378:metabolism*; D006684:HLA-DR Antigens / Q000378:metabolism*; D006801:Humans; D008840:Microfilament Proteins / Q000378:metabolism*; D017628:Microglia / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D015415:Biomarkers; D039481:CD11b Antigen; D002135:Calcium-Binding Proteins; D006684:HLA-DR Antigens; D008840:Microfilament Proteins; C100745:Aif1 protein, rat; C067980:CD68 antigen, human; D000097382:CD68 Molecule