title: Clinical application of sartorius tendon transposition during radical vulvectomy: a case control study of 58 cases at a single institution.
abstract: OBJECTIVE
  The aim of this study was to investigate the clinical effects of sartorius tendon transposition versus sartorius transposition during bilateral inguinal lymphadenectomy of radical vulvectomy.
  
  
  METHODS
  A total of 58 vulvar cancer patients who had surgery from May 2007 to October 2013, in which 30 patients received sartorius transposition and 28 patients received sartorius tendon transposition. All patients were matched by age, body mass index, stage, histology, and grade. Intraoperative variables and postoperative complications, recurrence, progression-free survival (PFS), and overall survival (OS) and postoperative life quality were compared and analyzed.
  
  
  RESULTS
  No significant differences were found at median surgical times and amounts of bleeding (p=0.316 and p=0.249, respectively), neither at the incidences of groin cellulitis and lymphocele (p=0.673 and p=0.473, respectively), but the recovery times of the inguinal wounds were shorter (p=0.026) and the incidences of wound break and chronic lymphedema were significantly decreased in the tendon transposition group (p=0.012 and p=0.022, respectively). Postoperative quality of life in tendon transposition group was significantly improved as indicated by the EORTC QLQ-C30 questionnaire. Recurrences were similar (p=0.346) and no significant differences were found at PFS and OS (p=0.990 and p=0.683, respectively).
  
  
  CONCLUSIONS
  Compared to sartorius transposition, sartorius tendon transposition during inguinal lymphadenectomy led to improved patient recovery, reduced postoperative complications, and improved life quality without compromising the outcomes.
authors.affiliation: Department of Gynecologic Oncology, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China. lilei04301596@163.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Gynecologic Oncology, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Xinxin
authors.initials: X
authors.lastname: Kou
authors.affiliation: Department of Gynecologic Oncology, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Feng
authors.affiliation: Department of Gynecologic Oncology, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Fenghua
authors.initials: F
authors.lastname: Liu
authors.affiliation: Department of Gynecologic Oncology, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Hongtu
authors.initials: H
authors.lastname: Chao
authors.affiliation: Department of Gynecologic Oncology, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Liying
authors.initials: L
authors.lastname: Wang
mesh_terms: D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008207:Lymphatic Metastasis; D059351:Organ Sparing Treatments / Q000379:methods; D013524:Surgical Flaps; D013530:Surgical Wound Infection / Q000209:etiology; D013710:Tendons / Q000637:transplantation*; D014844:Vulva / Q000601:surgery*; D014846:Vulvar Neoplasms / Q000601:surgery*
keywords: Bilateral Inguinal Lymphadenectomy; Radical Vulvectomy; Sartorius Transposition; Vulvar Carcinoma