title: Corneal wound healing after laser vision correction.
abstract: Any trauma can trigger a cascade of responses in tissues, with the purpose of safeguarding the integrity of the organ affected by the trauma and of preventing possible damage to nearby organs. Subsequently, the body tries to restore the function of the organ affected. The introduction of the excimer laser for keratorefractive surgery has changed the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. In recent years, with the increased understanding of the basic science of refractive errors, higher-order aberrations, biomechanics, and the biology of corneal wound healing, a reduction in the surgical complications of keratorefractive surgery has been achieved. The understanding of the cascade of events involved in the corneal wound healing process and the examination of how corneal wound healing influences corneal biomechanics and optics are crucial to improving the efficacy and safety of laser vision correction.
authors.affiliation: Department of Biotechnology and Medical-Surgical Sciences, 'Sapienza' University of Rome, Latina, Italy.
authors.forename: Leopoldo
authors.identifier: http://orcid.org/0000-0002-1190-3956
authors.initials: L
authors.lastname: Spadea
authors.affiliation: Department of Ophthalmology, Ospedali Riuniti Marche Nord, Fano-Pesaro, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Giammaria
authors.affiliation: Department of Biotechnology and Medical-Surgical Sciences, 'Sapienza' University of Rome, Latina, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Trabucco
mesh_terms: D003319:Corneal Stroma / Q000502:physiology*; D048988:Corneal Surgery, Laser; D019573:Epithelium, Corneal / Q000502:physiology*; D006801:Humans; D012029:Refraction, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*
keywords: Cornea; Treatment Lasers; Wound healing