title: Lessons Learned in Antibiotic Stewardship: Fluoroquinolone Use in Pediatrics.
abstract: The use of fluoroquinolones differs dramatically between adult and pediatric patients. For adults, they are the leading class of antibiotics prescribed in ambulatory care visits whereas in children, they are the least frequently prescribed class. The reasons for this difference in practice likely relate to perceptions of their potential for harm. This highlights the impact of physicians' perception of direct patient harm in antibiotic decision making which has implications for antibiotic stewardship.
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City;
authors.forename: Adam L
authors.initials: AL
authors.lastname: Hersh
authors.affiliation: Division of Infectious Diseases, Department of Pediatrics and The Center for Pediatric Clinical Effectiveness, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia;
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Gerber
authors.affiliation: Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Lauri A
authors.initials: LA
authors.lastname: Hicks
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City;
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Pavia
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D004352:Drug Resistance, Microbial; D024841:Fluoroquinolones / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D010372:Pediatrics / Q000379:methods*; D010818:Practice Patterns, Physicians'
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones
keywords: antibacterial agents; drug resistance; physician's practice patterns.