title: Compliance with the guidelines of the European Society of Cardiology and morbidity and mortality from infectious endocarditis.
abstract: OBJECTIVE
  The antibiotic treatment recommended for infectious endocarditis (IE) has a low level of evidence. Our objective was to determine whether compliance with the recommendations of the European Society of Cardiology (ESC) was related to lower inhospital morbidity and mortality for this disease.
  
  
  METHODS
  A retrospective study was conducted on 162 cases of IE diagnosed between 2005 and 2014. A propensity score-matching analysis was performed to determine the effect of treatment on hospital mortality.
  
  
  RESULTS
  There were no differences in terms of disease complications between the treatment groups. Hospital mortality was 29.2% when the treatment was adjusted to the guidelines and 28.2% when the treatment was not adjusted (OR=1.048; 95%CI: 0.442-2.484; P=.916).
  
  
  CONCLUSIONS
  The use of the ESC guidelines does not appear to translate into a reduction in hospital morbidity and mortality due to IE when compared with alternative antibiotic treatment regimens.
authors.affiliation: Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España. Electronic address: mrodest@gmail.com.
authors.forename: M
authors.initials: M
authors.lastname: Rodríguez Esteban
authors.affiliation: Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.
authors.forename: L
authors.initials: L
authors.lastname: Carballo Arzola
authors.affiliation: Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.
authors.forename: S
authors.initials: S
authors.lastname: Miranda Montero
authors.affiliation: Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.
authors.forename: M
authors.initials: M
authors.lastname: Farrais Villalba
authors.affiliation: Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.
authors.forename: J A
authors.initials: JA
authors.lastname: Medina García
authors.affiliation: Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.
authors.forename: J
authors.initials: J
authors.lastname: Ode Febles
keywords: Endocarditis infecciosa; Infectious endocarditis; Propensity score matching; Tratamiento; Treatment