title: [Monitoring of 4 patients with heparin-induced thrombocytopenia after complex congenital heart surgery].
abstract: From July 2013 to February 2015, 4 infant patients with complex congenital heart disease, who underwent open heart surgery in Xiangya Hospital of Central South University, were diagnosed as heparin-induced thrombocytopenia (HIT). After comprehensive treatments, such as intensive monitoring of the platelet count, close observation of thromboembolic skin lesions and close monitoring of argatroban therapy, 3 patients were cured and 1 died. HIT is rare but serious in patients who received heparin therapy. The incidence of mortality and thrombosis is very high. Early identification and diagnosis of high-risk groups can improve the prognosis.
authors.affiliation: Department of Cardiovascular Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Jianhui
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Department of Paediatrics, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Peng
authors.affiliation: Department of Cardiovascular Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.affiliation: Department of Cardiovascular Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Sisi
authors.initials: S
authors.lastname: Wei
authors.affiliation: Department of Cardiovascular Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Wenya
authors.initials: W
authors.lastname: Wu
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D001120:Arginine / Q000031:analogs & derivatives; D006348:Cardiac Surgical Procedures; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D007223:Infant; D010875:Pipecolic Acids / Q000627:therapeutic use; D010976:Platelet Count; D011379:Prognosis; D013449:Sulfonamides; D013921:Thrombocytopenia / Q000139:chemically induced*; D013927:Thrombosis
chemical_list: D000925:Anticoagulants; D010875:Pipecolic Acids; D013449:Sulfonamides; D006493:Heparin; D001120:Arginine; C031942:argatroban