title: Analysis of intima-media thickness of carotid artery and lipoprotein-associated phospholipase A2 in coronary heart diseases of different types.
abstract: OBJECTIVE
  To analyze intima-media thickness (IMT) of carotid artery and lipoprotein-associated phospholipase A2 (Lp-PLA2) in patients with coronary heart diseases of different types.
  
  
  METHODS
  A total of 1000 patients with suspicious coronary heart diseases were selected for carotid ultrasonography, coronary CT and Lp-PLA2, and divided into normal group, coronary atherosclerosis group and coronary heart disease group.
  
  
  RESULTS
  Statistical significance was observed in differences of IMT and Lp-PLA2 between normal group, coronary atherosclerosis group and coronary heart disease group. IMT and Lp-PLA2 were positively correlated. The worse the coronary heart disease, the higher the IMT or Lp-PLA2 values.
  
  
  CONCLUSIONS
  IMT and Lp-PLA2 ware closely correlated with coronary artery stenosis. IMT and Lp-PLA2 have certain predicting values for severity of coronary heart diseases. The combination of the two can improve noninvasive diagnosis of coronary heart diseases.
authors.forename: Ya
authors.initials: Y
authors.lastname: Li
mesh_terms: D043203:1-Alkyl-2-acetylglycerophosphocholine Esterase / Q000097:blood*; D002339:Carotid Arteries / Q000503:physiopathology; D059168:Carotid Intima-Media Thickness; D003324:Coronary Artery Disease / Q000503:physiopathology; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D011859:Radiography
chemical_list: D043203:1-Alkyl-2-acetylglycerophosphocholine Esterase
keywords: IMT; Lp-PLA2; coronary heart disease