title: AUTOMATIC PARCELLATION OF CORTICAL SURFACES USING RANDOM FORESTS.
abstract: Automatic and accurate parcellation of cortical surfaces into anatomically and functionally meaningful regions is of fundamental importance in brain mapping. In this paper, we propose a new method leveraging random forests and graph cuts methods to parcellate cortical surfaces into a set of gyral-based regions, using multiple surface atlases with manual labels by experts. Specifically, our method first takes advantage of random forests and auto-context methods to learn the optimal utilization of cortical features for rough parcellation and then the graph cuts method to further refine the parcellation for improved accuracy and spatial consistency. Particularly, to capitalize on random forests, we propose a novel definition of Haar-like features on cortical surfaces based on spherical mapping. The proposed method has been validated on cortical surfaces from 39 adult brain MR images, each with 35 regions manually labeled by a neuroanatomist, achieving the average Dice ratio of 0.902, higher than the-state-of-art methods.
authors.affiliation: Department of Computer Science, University of North Carolina at Chapel Hill, NC, USA ; Department of Radiology and BRIC, University of North Carolina at Chapel Hill, NC, USA.
authors.forename: Yu
authors.initials: Y
authors.lastname: Meng
authors.affiliation: Department of Radiology and BRIC, University of North Carolina at Chapel Hill, NC, USA.
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.affiliation: Department of Computer Science, University of North Carolina at Chapel Hill, NC, USA ; Department of Radiology and BRIC, University of North Carolina at Chapel Hill, NC, USA.
authors.forename: Yaozong
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Department of Radiology and BRIC, University of North Carolina at Chapel Hill, NC, USA.
authors.forename: Dinggang
authors.initials: D
authors.lastname: Shen
keywords: Cortical surface parcellation; Haar-like features; context feature; graph cuts; random forests