title: Sister Mary Joseph Nodule: A Rare Presentation of Squamous Cell Carcinoma of the Cervix.
abstract: BACKGROUND
  Sister Mary Joseph nodule refers to metastatic malignancy of the periumbilical region. Umbilical metastasis is an indicator of advanced malignant disease.
  
  
  METHODS
  We present the case of an 88-year-old patient presenting with postmenopausal vaginal bleeding, inguinal lymphadenopathy, and physical findings of a palpable umbilical nodule (Sister Mary Joseph nodule). Further workup was consistent with metastatic squamous cell carcinoma of the cervix.
  
  
  CONCLUSIONS
  Because Sister Mary Joseph nodule may be the only manifestation of underlying malignancy, thorough physical examination plays an important role in diagnosing the malignancy in a more confined state that may have a positive impact on the patient's length of survival.
authors.affiliation: Division of Hematology and Oncology, The Brooklyn Hospital Center, Brooklyn, NY.
authors.forename: Nay Min
authors.initials: NM
authors.lastname: Tun
authors.affiliation: Department of Internal Medicine, The Brooklyn Hospital Center, Brooklyn, NY.
authors.forename: Linus
authors.initials: L
authors.lastname: Yoe
keywords: Carcinoma–squamous cell; Sister Mary Joseph nodule; neoplasm metastasis; uterine cervical neoplasms