title: [Bioaccessibility of heavy metal in wild Artemisia annua and its health risk assessment].
abstract: In this study, we investigate the bioaccessibility of heavy metals (Cu, Pb, As, Cd and Hg) in wild Artemisia annua and use target hazard quotients (THQ) proposed by US Environmental Protection Agency to assess the health risk under the heavy metal exposure. The results showed that the bioaccessibility of Cu, Pb, As, Cd and Hg in A. annua are 0.77, 0.66, 0.46, 0.68 and 0, respectively, and that the value of THQ for adults and children were 0.030 and 0.025 calculated by risk assessment model. The results indicated that the heavy metals in A. annua were not able to be completely absorbed by human body and that their contents were in a safe range. In this study, by combining the bioavailability of heavy metal and health risk assessment, we assessed the security of heavy metals of wild A. annua, which will provide reference for the standard of heavy metals for medicinal materials.
authors.forename: Liang-yun
authors.initials: LY
authors.lastname: Zhou
authors.forename: Hong
authors.initials: H
authors.lastname: Yue
authors.forename: Xuan
authors.initials: X
authors.lastname: Li
authors.forename: Ge
authors.initials: G
authors.lastname: Mo
authors.forename: Li-ping
authors.initials: LP
authors.lastname: Kang
authors.forename: Lan-ping
authors.initials: LP
authors.lastname: Guo
mesh_terms: D031172:Artemisia annua / Q000737:chemistry* / Q000378:metabolism; D003257:Consumer Product Safety; D004340:Drug Contamination; D006801:Humans; D019216:Metals, Heavy / Q000032:analysis* / Q000378:metabolism*; D018570:Risk Assessment; D012989:Soil Pollutants / Q000032:analysis / Q000378:metabolism
chemical_list: D019216:Metals, Heavy; D012989:Soil Pollutants