title: Contrast-based sensorless adaptive optics for retinal imaging.
abstract: Conventional adaptive optics ophthalmoscopes use wavefront sensing methods to characterize ocular aberrations for real-time correction. However, there are important situations in which the wavefront sensing step is susceptible to difficulties that affect the accuracy of the correction. To circumvent these, wavefront sensorless adaptive optics (or non-wavefront sensing AO; NS-AO) imaging has recently been developed and has been applied to point-scanning based retinal imaging modalities. In this study we show, for the first time, contrast-based NS-AO ophthalmoscopy for full-frame in vivo imaging of human and animal eyes. We suggest a robust image quality metric that could be used for any imaging modality, and test its performance against other metrics using (physical) model eyes.
authors.affiliation: Department of Optometry and Vision Sciences, University of Melbourne, Australia.
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Department of Optometry and Vision Sciences, University of Melbourne, Australia.
authors.forename: Phillip
authors.initials: P
authors.lastname: Bedggood
authors.affiliation: Department of Optometry and Vision Sciences, University of Melbourne, Australia.
authors.forename: Bang
authors.initials: B
authors.lastname: Bui
authors.affiliation: Department of Optometry and Vision Sciences, University of Melbourne, Australia.
authors.forename: Christine T O
authors.initials: CT
authors.lastname: Nguyen
authors.affiliation: Department of Optometry and Vision Sciences, University of Melbourne, Australia.
authors.forename: Zheng
authors.initials: Z
authors.lastname: He
authors.affiliation: Department of Optometry and Vision Sciences, University of Melbourne, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Metha
keywords: (010.1080) Active or adaptive optics; (170.3880) Medical and biological imaging; (170.4460) Ophthalmic optics and devices; (330.4875) Optics of physiological systems