title: Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases.
abstract: Efficient conversion of ketones into kinetic enol phosphates under mild and accessible conditions has been realised using the developed methods with di-tert-butylmagnesium and bismesitylmagnesium. Optimisation of the quench protocol resulted in high yields of enol phosphates from a range of cyclohexanones and aryl methyl ketones, with tolerance of a range of additional functional units.
authors.affiliation: Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, UK. w.kerr@strath.ac.uk.
authors.forename: William J
authors.initials: WJ
authors.lastname: Kerr
authors.forename: David M
authors.initials: DM
authors.lastname: Lindsay
authors.forename: Vipulkumar K
authors.initials: VK
authors.lastname: Patel
authors.forename: Muralikrishnan
authors.initials: M
authors.lastname: Rajamanickam
mesh_terms: D002244:Carbon / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D007700:Kinetics; D008274:Magnesium / Q000737:chemistry*; D015394:Molecular Structure; D010710:Phosphates / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007659:Ketones; D010710:Phosphates; D002244:Carbon; D008274:Magnesium