title: What do animal experiments tell us that in vitro systems cannot? The Human Toxome Project.
authors.affiliation: Department of Environmental Health & Center for Environmental Genetics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA; Department of Pediatrics & Molecular Developmental Biology, Division of Human Genetics, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA. Electronic address: dan.nebert@uc.edu.
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Nebert
authors.affiliation: Department of Physiology and Pharmacology, Section of Pharmacogenetics, Karolinska Institutet, 171 77 Stockholm, Sweden. Electronic address: magnus.ingelman-sundberg@ki.se.
authors.forename: Magnus
authors.initials: M
authors.lastname: Ingelman-Sundberg
mesh_terms: D032761:Animal Experimentation; D000818:Animals; D052244:Endocrine Disruptors / Q000633:toxicity; D004967:Estrogens / Q000633:toxicity; D006801:Humans; D061986:MCF-7 Cells; D018675:Toxicity Tests / Q000379:methods*; D014116:Toxicology / Q000379:methods*
chemical_list: D052244:Endocrine Disruptors; D004967:Estrogens
keywords: Cell culture studies; Human Toxome Project; Human vs mouse PPARA; Intact animal studies; In vitro studies; Mouse genetics; Toxicity and cancer by fibrate drugs; Toxicity and cancer by oral benzo[a]pyrene