title: Kinesin-5: A Team Is Just the Sum of Its Parts.
abstract: How the cell builds a spindle remains an open question. In this issue of Developmental Cell, Shimamoto, Forth, and Kapoor (2015) show that kinesin-5 motor ensembles can exert sliding forces that scale with microtubule overlap length. This behavior could allow microtubule architecture-dependent modulation of force and contribute to spindle self-organization.
authors.affiliation: Department of Cell & Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.
authors.forename: Christina L
authors.initials: CL
authors.lastname: Hueschen
authors.affiliation: Department of Cell & Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA; Tetrad Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.
authors.forename: Alexandra F
authors.initials: AF
authors.lastname: Long
authors.affiliation: Department of Cell & Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Tetrad Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: sophie.dumont@ucsf.edu.
authors.forename: Sophie
authors.initials: S
authors.lastname: Dumont
mesh_terms: D000818:Animals; D003432:Cross-Linking Reagents / Q000378:metabolism*; D016547:Kinesins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008941:Spindle Apparatus / Q000502:physiology*; D029867:Xenopus Proteins / Q000378:metabolism*; D014982:Xenopus laevis / Q000254:growth & development*
chemical_list: D003432:Cross-Linking Reagents; D029867:Xenopus Proteins; D016547:Kinesins