title: Parent-Reported Health-Related Quality of Life in Children With Traumatic Brain Injury: A Prospective Study.
abstract: OBJECTIVE
  To identify which specific aspects of health-related quality of life (HRQL) are affected by traumatic brain injury (TBI) injury severity (Severity), time since injury (Time), and the interaction between Severity and Time, in a pediatric sample. It was hypothesized that Severity would decrease HRQL, Time would increase HRQL, and time to recover would be protracted for children with severe TBI.
  
  
  METHODS
  This study followed a pediatric sample (n = 182, aged 6-14 years, recruited through three Australian hospitals) who sustained a mild or moderate-severe TBI across 3, 6, 12, and 18 months post-TBI. 12 specific HRQL outcomes were assessed via the Child Health Questionnaire-Parent Form 50 questionnaire.
  
  
  RESULTS
  Dimensions of HRQL were differentially affected. Children with moderate-severe TBI generally experienced greater initial dysfunction than children with mild TBI; however, this difference disappeared by 18 months post-TBI.
  
  
  CONCLUSIONS
  Specific time points where HRQL outcomes may remediate are identified, and clinical recommendations regarding intervention strategies are discussed.
authors.affiliation: Centre of National Research on Disability and Rehabilitation Medicine, The University of Queensland, e.brown5@uq.edu.au.
authors.forename: Erin A
authors.initials: EA
authors.lastname: Brown
authors.affiliation: Centre of National Research on Disability and Rehabilitation Medicine, The University of Queensland.
authors.forename: Justin
authors.initials: J
authors.lastname: Kenardy
authors.affiliation: Centre of National Research on Disability and Rehabilitation Medicine, The University of Queensland.
authors.forename: Bronwyn
authors.initials: B
authors.lastname: Chandler
authors.affiliation: Murdoch Children's Research Institute, Royal Children's Hospital, and.
authors.forename: Vicki
authors.initials: V
authors.lastname: Anderson
authors.affiliation: Queensland Paediatric Rehabilitation Service, Royal Children's Hospital.
authors.forename: Lynne
authors.initials: L
authors.lastname: McKinlay
authors.affiliation: Centre of National Research on Disability and Rehabilitation Medicine, The University of Queensland.
authors.forename: Robyne
authors.initials: R
authors.lastname: Le Brocque
mesh_terms: D000293:Adolescent; D001315:Australia; D001930:Brain Injuries / Q000523:psychology*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010290:Parents / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires
keywords: accidents and injuries; adolescents; assessment; children; quality of life.