title: Sodium Excretion Pattern at 1 Year After Kidney Transplantation and High Blood Pressure.
abstract: BACKGROUND
  High blood pressure (BP) after kidney transplantation decreases graft and patient survival. There is a causal relationship between high salt intake and increased BP in the general population, but the role of salt intake on post-transplant hypertension remains controversial. The aims of our study were to determine the pattern of salt intake in the first year post-transplantation and its influence on BP in our kidney transplant population.
  
  
  METHODS
  We selected 270 deceased-donor kidney transplant recipients with graft survival longer than 1 year and at least 1 adequate 24-h urinary sodium excretion measurement at the first year visit in order to be included in the analysis.
  
  
  RESULTS
  Some 87.0% patients had a sodium excretion (mean 165±73 mmol/day) higher than recommended. Male and younger recipients with a high body mass index had a higher sodium excretion. Among other variables, sodium excretion was independently related to higher systolic (b 3.529 per 100 mmol/day, 95%CI 0.725-6.334, p=0.014) and diastolic (b 1.866 per 100 mmol/day, 95%CI 0.237-3.496, p=0.025) BP.
  
  
  CONCLUSIONS
  A high percentage of kidney transplant recipients have salt intake higher than recommended, contributing to increased BP. Measurement of 24-h urinary sodium excretion identifies non-compliant kidney transplant recipients who need intervention to improve BP control and graft outcome.
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Emilio
authors.initials: E
authors.lastname: Rodrigo
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Monfá
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Zoila
authors.initials: Z
authors.lastname: Albines
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Mara
authors.initials: M
authors.lastname: Serrano
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Gema
authors.initials: G
authors.lastname: Fernandez-Fresnedo
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Ruiz
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Celestino
authors.initials: C
authors.lastname: Piñera
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: Palomar
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Martín-Penagos
authors.affiliation: Nephrology Service, University Hospital "Marqués de Valdecilla", University of Cantabria, Santander, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Arias
mesh_terms: D000328:Adult; D000367:Age Factors; D016009:Chi-Square Distribution; D015331:Cohort Studies; D005260:Female; D006084:Graft Rejection / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000175:diagnosis; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000401:mortality; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors; D012982:Sodium, Dietary / Q000009:adverse effects / Q000652:urine*; D015996:Survival Rate; D066027:Transplant Recipients
chemical_list: D012982:Sodium, Dietary