title: Perioperative Analgesic Management of Newborn Bladder Exstrophy Repair Using a Directly Placed Tunneled Epidural Catheter with 0.1% Ropivacaine.
abstract: Effective multimodal analgesia and sedation reduce the postoperative morbidity and mortality associated with newborn bladder exstrophy repair. Epidural analgesia is safe and effective for major surgery in neonates and infants, reducing the need for muscle relaxants, opioids, and ventilator support postoperatively. The risk of epidural catheter colonization typically dictates removal after 3 to 5 days. Tunneling the catheter subcutaneously reduces the risk of colonization, providing prolonged analgesia for patients requiring an extended immobilization to prevent compromise of the repair. In this report, we describe the postoperative analgesic management of an infant undergoing bladder exstrophy repair using a directly placed tunneled epidural catheter with ropivacaine 0.1% infusion. Because of the prolonged infusion, we also monitored plasma ropivacaine levels to preclude systemic toxicity from local anesthetic overdose.
authors.affiliation: From the Department of Anesthesia, Pain Center, Akron Children's Hospital, Akron, Ohio.
authors.forename: Ibrahim S
authors.initials: IS
authors.lastname: Farid
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Kendrick
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Adamczyk
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Lukas
authors.forename: Eric Z
authors.initials: EZ
authors.lastname: Massanyi
mesh_terms: D000577:Amides / Q000008:administration & dosage*; D015360:Analgesia, Epidural / Q000295:instrumentation* / Q000379:methods; D000779:Anesthetics, Local / Q000008:administration & dosage; D001746:Bladder Exstrophy / Q000601:surgery*; D002404:Catheterization / Q000379:methods; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000601:surgery*; D010149:Postoperative Pain / Q000517:prevention & control*; D019990:Perioperative Care / Q000295:instrumentation / Q000379:methods; D000077212:Ropivacaine
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine