title: Is adjuvant radiotherapy necessary for FIGO stage 1a grade 2 endometrial endometrioid adenocarcinoma?
abstract: OBJECTIVE
  The impact of adjuvant radiotherapy on the rates of survival and local recurrence was analyzed in patients diagnosed with International Federation of Gynecology and Obstetrics (FIGO) stage 1a grade 2 endometrial endometrioid adenocarcinoma.
  
  
  METHODS
  Medical records of 82 patients diagnosed and treated for FIGO stage 1a grade 2 endometrial endometrioid adenocarcinoma were reviewed retrospectively. A group of 59 patients who received postoperative radiotherapy was compared with a control group of 23 subjects treated without adjuvant radiotherapy; the duration of survival as well as the local recurrence and metastasis rates were evaluated in both groups.
  
  
  RESULTS
  The analysis of patient data has revealed the rate of local recurrence as 4.3% vs. 1.7% (p=0.485), the rate of distant metastasis as 4.3% vs. 6.9% (p=1.000), and the mean survival time as 83.6±38.7 vs. 81.5±37.5 months (p=0.828) in the adjuvant radiotherapy and control groups, respectively.
  
  
  CONCLUSIONS
  In the presented study, adjuvant radiotherapy failed to improve the overall survival of the patients in the low-risk group (stage 1a grade 2). With the addition of the significant risk of radiation toxicity, it is highly probable that these patients will not benefit from postoperative radiotherapy. Close observation should be performed following the primary surgery in this patient group. Nevertheless, it should also be considered that adjuvant radiotherapy is a very effective treatment modality for the recovery of patients with vaginal relapse.
authors.affiliation: Clinic of Obstetrics and Gynecology, Ardahan State Hospital, Ardahan, Turkey.
authors.forename: Abdurrahman Hamdi
authors.initials: AH
authors.lastname: İnan
authors.affiliation: Department of Obstetrics and Gynecology, Marmara University Pendik Training and Research Hospital, İstanbul, Turkey.
authors.forename: Gülçin Şahin
authors.initials: GŞ
authors.lastname: Ersoy
authors.affiliation: Department of Obstetrics and Gynecology, Divison of Gynecologic Oncology, Erzincan University Faculty of Medicine, Erzincan, Turkey.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yıldırım
authors.affiliation: Clinic of Obstetrics and Gynecology, Ardahan State Hospital, Ardahan, Turkey.
authors.forename: Tutku
authors.initials: T
authors.lastname: Gürbüz
authors.affiliation: Department of Obstetrics and Gynecology, Selçuk University Faculty of Medicine, Konya, Turkey.
authors.forename: Ayşe Gül
authors.initials: AG
authors.lastname: Kebapçılar
authors.affiliation: Clinic of Obstetrics and Gynecology, Divison of Gynecologic Oncology, İzmir Aegean Obstetrics and Gynecology Education and Research Hospital, İzmir, Turkey.
authors.forename: Merih
authors.initials: M
authors.lastname: Hanhan
keywords: Endometrial cancer; adjuvant radiotherapy; mean survival time