title: Elements as Direct Feedstocks for Organic Synthesis: Fe/I2/O2 for Diamination of 2-Cyclohexenones with 2-Aminopyrimidine and 2-Aminopyridines.
abstract: Elements as feedstocks for organic synthesis, the trio of metallic iron, molecular iodine, and dioxygen, were found to be an excellent tool for oxidative regioselective diamination of conjugated enones with 2-aminopyrimidine (a guanidine surrogate) and 2-aminopyridines leading to unaromatized coupled products in moderate to good yields.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS-ICSN UPR 2301, Université Paris-Sud , 1 avenue de la Terrase, 91198 Gif-sur-Yvette Cedex, France.
authors.forename: Thanh Binh
authors.initials: TB
authors.lastname: Nguyen
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS-ICSN UPR 2301, Université Paris-Sud , 1 avenue de la Terrase, 91198 Gif-sur-Yvette Cedex, France.
authors.forename: Mathilde
authors.initials: M
authors.lastname: Corbin
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS-ICSN UPR 2301, Université Paris-Sud , 1 avenue de la Terrase, 91198 Gif-sur-Yvette Cedex, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Retailleau
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS-ICSN UPR 2301, Université Paris-Sud , 1 avenue de la Terrase, 91198 Gif-sur-Yvette Cedex, France.
authors.forename: Ludmila
authors.initials: L
authors.lastname: Ermolenko
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS-ICSN UPR 2301, Université Paris-Sud , 1 avenue de la Terrase, 91198 Gif-sur-Yvette Cedex, France.
authors.forename: Ali
authors.initials: A
authors.lastname: Al-Mourabit
mesh_terms: D000586:Amination; D000631:Aminopyridines / Q000737:chemistry*; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D018360:Crystallography, X-Ray; D003512:Cyclohexanones / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D011743:Pyrimidines / Q000737:chemistry*
chemical_list: D000631:Aminopyridines; D003512:Cyclohexanones; D011743:Pyrimidines; C012180:2-aminopyrimidine; C028215:2-cyclohexen-1-one; D007501:Iron; D010100:Oxygen; C032439:alpha-aminopyridine