title: [Consensus Document on post-exposure prophylaxis against HIV, HBV and HCV in adults and children].
abstract: OBJECTIVE
  This consensus document is an update of occupational and non-occupational prophylaxis guidelines in HIV-patients, promoting appropriate use of them, from the standpoint of care.
  
  
  METHODS
  This document has been approved by expert panel of SPNS, GESIDA, SEMST and different scientific societies related, after reviewing the results of efficacy and safety clinical trials, cohort and pharmacokinetic studies published in biomedical journals (PubMed and Embase) or presented at conferences and different guidelines. The strength of the recommendation and gradation of their evidence are based on the GRADE system.
  
  
  RESULTS
  We have developed recommendations for assessing the risk of transmission in different types of exposure situations in which post-exposure prophylaxis should be recommended, special circumstances to consider, patterns of antiretroviral with the start and duration of early monitoring of tolerance and adherence to treatment, the subsequent monitoring of exposed persons regardless of whether they received post-exposure prophylaxis or not, and the need of psychological support.
  
  
  CONCLUSIONS
  These new guidelines updated previous recommendations regarding occupational post-exposure prophylaxis and non-occupational, in adults and children.
authors.affiliation: Electronic address: rpolor@msssi.es
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D015658:HIV Infections / Q000188:drug therapy*; D006509:Hepatitis B / Q000188:drug therapy*; D006526:Hepatitis C / Q000188:drug therapy*; D006801:Humans; D056990:Post-Exposure Prophylaxis
chemical_list: D019380:Anti-HIV Agents; D000998:Antiviral Agents
keywords: HBV; HIV; HVC; Non-occupational post-exposure prophylaxis; Occupational post-exposure prophylaxis; Profilaxis postexposición no ocupacional; Profilaxis postexposición ocupacional; VHB; VHC; VIH