title: Comparative Analysis of Antioxidant Properties of Comenic Acid and Potassium Comenate in Modeled Immobilization Stress.
abstract: We studied antioxidant protective effect of comenic acid and potassium comenate in doses of 2, 4, and 8 mg/kg under conditions of oxidative stress in the brain of mice exposed to immobilization stress. Administration of potassium comenate and comenic acid in the above doses for 3 days before stress prevented the development of oxidative processes in the brain of stressed animals. The antioxidant effect of potassium comenate more pronounced.
authors.affiliation: A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia. balizfarm@mail.ru.|Baliz Farm, Krasnodar, Russia. balizfarm@mail.ru.
authors.forename: L V
authors.initials: LV
authors.lastname: Shurygina
authors.affiliation: A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia.
authors.forename: E I
authors.initials: EI
authors.lastname: Zlishcheva
authors.affiliation: A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Khablyuk
authors.affiliation: A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia.
authors.forename: A N
authors.initials: AN
authors.lastname: Kravtsova
authors.affiliation: Baliz Farm, Krasnodar, Russia.
authors.forename: N O
authors.initials: NO
authors.lastname: Abramova
authors.affiliation: A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia.
authors.forename: L I
authors.initials: LI
authors.lastname: Zlishcheva
authors.affiliation: A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University, Krasnodar, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Kravtsov
mesh_terms: D000818:Animals; D021461:Animals, Outbred Strains; D000975:Antioxidants / Q000494:pharmacology*; D002264:Carboxylic Acids / Q000494:pharmacology*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D051379:Mice; D018384:Oxidative Stress; D011753:Pyrones / Q000494:pharmacology*; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000378:metabolism
chemical_list: D000975:Antioxidants; D002264:Carboxylic Acids; D011753:Pyrones; C488376:comenic acid; D008315:Malondialdehyde
keywords: comenic acid; free radical oxidation; malondialdehyde; mouse brain; potassium comenate