title: Enlarged Parent Artery Lumen at Aneurysmal-Neck Segment in Wide-Necked Distal Internal Carotid Artery Aneurysms.
abstract: OBJECTIVE
  Hypothesizing that the parent artery (PA) diameter of the aneurysm-neck segment is larger than those of normal segments, especially in wide-necked aneurysm cases, we conducted 3D angiographic analyses in wide-necked aneurysm cases focusing on the luminal morphologic change of the PA.
  
  
  METHODS
  Under the approval of local IRB, we enrolled 26 patients with distal internal carotid artery (ICA) aneurysms, which were treated with stent assisted coiling. The PA diameters along the centerline were measured at 6 points with built-in software by two observers. Those 6 points were P1 and P2 proximally, P3 and P4 at the aneurysm ostium margins, and P5 and P6 distally. We performed an ANOVA test and a Bonferroni method for post hoc analyses. Linear regression analysis was performed to find any morphologic influencing factors.
  
  
  RESULTS
  There were 20 distal ICA aneurysms out of 26 consecutive cases after exclusion. The differences in diameter at each point were statistically significant (p<0.0001). On post hoc analyses, the difference between P4 and P5 was significant both in maximum and mean PA diameters (p<0.0001 and p<0.001, respectively). Multivariate analyses failed to reveal any morphological influencing factor.
  
  
  CONCLUSIONS
  PAs harboring a wide-necked aneurysm requiring stent assistance for coiling showed significant enlargement of the lumen, especially at the distal transition segment of the aneurysm ostium and the PA.
authors.affiliation: Department of Medicine, University of Ulsan College of Medicine, Ulsan, Korea.
authors.forename: Jong Won
authors.initials: JW
authors.lastname: Lee
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, Seoul, Korea.
authors.forename: Jung Min
authors.initials: JM
authors.lastname: Woo
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, Seoul, Korea.
authors.forename: Ok Kyun
authors.initials: OK
authors.lastname: Lim
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, Seoul, Korea.
authors.forename: Ye-Eun
authors.initials: YE
authors.lastname: Jo
authors.affiliation: Department of Radiology, Chung-Ang University College of Medicine, Seoul, Korea.
authors.forename: Jae Kyun
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Angiovention, Gyeonggi-do, Korea.
authors.forename: Eun Sang
authors.initials: ES
authors.lastname: Kim
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, Seoul, Korea. ; Department of Medicine, University of Ulsan College of Medicine, Ulsan, Korea.
authors.forename: Deok Hee
authors.initials: DH
authors.lastname: Lee
keywords: Cerebral aneurysms; Cerebral angiography; Intracranial stenting; Parent artery; Vascular morphology