title: Low photobleaching and high emission depletion efficiency: the potential of AIE luminogen as fluorescent probe for STED microscopy.
abstract: We present a preliminary study which explores the potential of aggregation-induced emission (AIE) luminogen as a new fluorescent probe for STED microscopy. Compared with Coumarin 102, which is a commonly used organic fluorophore in STED microscopy, HPS, a typical AIE luminogen, is more resistant to photobleaching. In addition, HPS-doped nanoparticles have higher emission depletion efficiency than Coumarin 102 in organic solution. These two advantages of AIE luminogen can facilitate the improvement of spatial resolution, as well as long-term imaging, in STED microscopy. AIE luminogen will be a promising candidate for STED microscopy in the future.
authors.forename: Jiaxin
authors.initials: J
authors.lastname: Yu
authors.forename: Xianhe
authors.initials: X
authors.lastname: Sun
authors.forename: Fuhong
authors.initials: F
authors.lastname: Cai
authors.forename: Zhenfeng
authors.initials: Z
authors.lastname: Zhu
authors.forename: Anjun
authors.initials: A
authors.lastname: Qin
authors.forename: Jun
authors.initials: J
authors.lastname: Qian
authors.forename: Benzhong
authors.initials: B
authors.lastname: Tang
authors.forename: Sailing
authors.initials: S
authors.lastname: He