title: Detection of Antibodies In Vitro Binding to Endothelial Cells in the Sera from Women with Normal Pregnancy and Preeclampsia.
abstract: Activity of serum antibodies in vitro binding to endothelial cells in women with normal pregnancy and preeclampsia was studied. Flow cytometry detected peculiarities of antibody binding to endothelial cells in health and disease. Detection of antiendothelial antibodies in trimesters II and III can be diagnostically important in preeclampsia.
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia. mmz@mail.ru.|D. O. Ott Research Institute of Obstetrics and Gynecology, North Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia. mmz@mail.ru.
authors.forename: M M
authors.initials: MM
authors.lastname: Ziganshina
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Nikolaeva
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: E O
authors.initials: EO
authors.lastname: Stepanova
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: L V
authors.initials: LV
authors.lastname: Krechetova
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: N E
authors.initials: NE
authors.lastname: Kan
authors.affiliation: D. O. Ott Research Institute of Obstetrics and Gynecology, North Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia.
authors.forename: D I
authors.initials: DI
authors.lastname: Sokolov
authors.affiliation: D. O. Ott Research Institute of Obstetrics and Gynecology, North Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Sel'kov
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: G T
authors.initials: GT
authors.lastname: Sukhikh
mesh_terms: D001323:Autoantibodies / Q000097:blood*; D001666:Binding Sites, Antibody; D016022:Case-Control Studies; D002460:Cell Line; D042783:Endothelial Cells / Q000276:immunology*; D004730:Endothelium, Vascular / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D011225:Pre-Eclampsia / Q000097:blood* / Q000276:immunology; D011247:Pregnancy; D011485:Protein Binding
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M
keywords: antibody binding activity; antiendothelial antibodies (AEAB); flow cytofluorometry; preeclampsia; pregnancy