title: Differentiation Between Sickle Cell Anemia and S/β⁰ Thalassemia.
abstract: METHODS
  37-year-old man of half African and half Italian ethnicity.
  Sickle cell crisis (SCC).
  The patient had severe pain in his lower back that radiated to both thighs. He had been admitted twice in the previous 2 weeks at another hospital due to SCC. Each time, he had been discharged with a prescription for oxycodone. His condition did not respond to the pain medicine; his pain remained uncontrollable.
  
  
  METHODS
  The patient has had multiple sickle cell crises since childhood and is a former smoker. He denied alcohol consumption or illegal drug use.
  
  
  RESULTS
  The patient had normal vital signs. No splenomegaly was present.
  Both parents carry sickle cell thalassemia.
  
  
  RESULTS
  Table 1, Table 2, and Image 1.
authors.affiliation: Department of Biology, University of North Florida, Gainesville, FL vfanestil@yahoo.com.
authors.forename: Vichaka
authors.initials: V
authors.lastname: Fanestil
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL.
authors.forename: Carleen
authors.initials: C
authors.lastname: Van Siclen
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000175:diagnosis*; D006801:Humans; D008297:Male; D009294:Narcotics / Q000627:therapeutic use; D010098:Oxycodone / Q000627:therapeutic use; D017086:beta-Thalassemia / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D009294:Narcotics; D010098:Oxycodone
keywords: S/ß0 thalassemia; hemoglobin S; hemoglobinopathy; sickle cell anemia; sickle cell crisis; sickling disorders