title: Emergence of ONPG-negative Shigella sonnei in Shanghai, China.
abstract: Shigella sonnei has become predominant species causing shigellosis in Shanghai. Two hundred ninety-three S. sonnei were isolated in sentinel hospitals of Shanghai in 2011. We found an emergence of 8 strains of S. sonnei with negative phenotype for o-nitrophenyl-β-d-galactopyranoside in late August, which showed distinct pulsed-field gel electrophoresis patterns from the other 285 S. sonnei and had genes deletion in lac and mhp operons.
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Shaofu
authors.initials: S
authors.lastname: Qiu
authors.affiliation: Shanghai Municipal Centre for Disease Control and Prevention, Shanghai, China.
authors.forename: Xuebin
authors.initials: X
authors.lastname: Xu
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Wenli
authors.initials: W
authors.lastname: Su
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Beibei
authors.initials: B
authors.lastname: Liang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Qiuxia
authors.initials: Q
authors.lastname: Ma
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Chaojie
authors.initials: C
authors.lastname: Yang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Lihua
authors.initials: L
authors.lastname: Qi
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Shengjie
authors.initials: S
authors.lastname: Yi
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Zhihao
authors.initials: Z
authors.lastname: Wu
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Ligui
authors.initials: L
authors.lastname: Wang
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Rongzhang
authors.initials: R
authors.lastname: Hao
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China. Electronic address: hongbinsong@263.net.
authors.forename: Hongbin
authors.initials: H
authors.lastname: Song
authors.affiliation: Department of Science and Technology, Academy of Military Medical Sciences, Beijing, China. Electronic address: sunys1964@hotmail.com.
authors.forename: Yansong
authors.initials: Y
authors.lastname: Sun
mesh_terms: D000328:Adult; D015373:Bacterial Typing Techniques; D002681:China; D004405:Dysentery, Bacillary / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D017353:Gene Deletion; D005838:Genotype; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D009598:Nitrophenylgalactosides / Q000378:metabolism*; D010641:Phenotype; D012764:Shigella sonnei / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D055815:Young Adult
chemical_list: C055012:2-nitrophenylgalactoside; D009598:Nitrophenylgalactosides
keywords: Emergence; Gene deletion; ONPG-negative; Phenotype; Shigella sonnei