title: Synthesis and characterization of composite polymer, polyethylene glycol grafted flower-like cupric nano oxide for solid phase microextraction of ultra-trace levels of benzene, toluene, ethyl benzene and o-xylene in human hair and water samples.
abstract: In this research, poly (ethylene glycol)-poly (ethylene glycol) grafted flower-like cupric oxidenano particles (PEG-PEG-g-CuO NPs) as a novel fiber coating of solid-phase microextraction (SPME) were synthesized by using sol-gel technology. This fiber was successfully applied to extract and determine the ultra-trace levels of benzene, toluene, ethyl benzene and o-xylene in human hair using head space-solid-phase microextraction (HS-SPME) coupled to gas chromatography-flame ionization detector. Characterization and chemical composition of the nano particle was performed by Fourier transform infrared spectroscopy (FT-IR), energy dispersion spectroscopy (EDS) and back scatter analysis (BSA). These methods confirmed the successful fabrication of PEG-g-CuO NPs. The surface morphology of the fibers were inspected by scanning electron microscopy. The scanning electron microscopy (SEM) revealed many "crack-like" features and highly porous structure on the surface of fiber. The synthesized nanocomposites were used for preconcentration and extraction of benzene, toluene, ethyl benzene and o-xylene (BTEX). The effects of operating parameters such as: desorption temperature and time, extraction temperature, extraction time, stirring speed and salt effect were investigated and optimized. Under the optimal conditions, the method detection limits and the limits of quantification were between 0.00025-50.00000pgmL(-1) and 0.00200-200.00000pgmL(-1), respectively. Linearity was observed over a range 0.00200-200000.00000pgmL(-1). The relative standard deviations for one fiber (repeatability; n=5) were obtained from 3.30 up to 5.01% and between fibers or batch to batch (n=3; reproducibility) in the range of 3.63-6.21%. The developed method was successfully applied to simultaneous determination of BTEX in human hairs, tap water and distillate water.
authors.affiliation: Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Iran. Electronic address: asyazdi@um.ac.ir.
authors.forename: Ali
authors.initials: A
authors.lastname: Sarafraz-Yazdi
authors.affiliation: Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Iran.
authors.forename: Amene
authors.initials: A
authors.lastname: Zendegi-Shiraz
authors.affiliation: Department of Chemistry, Faculty of Sciences, Payame Noor University, Mashhad, Iran.
authors.forename: Zarrin
authors.initials: Z
authors.lastname: Es'haghi
authors.affiliation: Pharmaceutical Research Center and School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Hassanzadeh-Khayyat
mesh_terms: D001554:Benzene / Q000032:analysis; D001555:Benzene Derivatives / Q000032:analysis*; D002849:Chromatography, Gas / Q000379:methods; D003300:Copper / Q000737:chemistry*; D005410:Flame Ionization; D005618:Fresh Water / Q000737:chemistry; D006197:Hair / Q000737:chemistry*; D006801:Humans; D053758:Nanoparticles; D011092:Polyethylene Glycols / Q000138:chemical synthesis / Q000737:chemistry*; D015203:Reproducibility of Results; D052617:Solid Phase Microextraction / Q000379:methods*; D017550:Spectroscopy, Fourier Transform Infrared; D014050:Toluene / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014992:Xylenes / Q000032:analysis
chemical_list: D001555:Benzene Derivatives; D014874:Water Pollutants, Chemical; D014992:Xylenes; D014050:Toluene; D011092:Polyethylene Glycols; D003300:Copper; D001554:Benzene; C004912:ethylbenzene; C030973:cupric oxide; C026114:2-xylene
keywords: BTEX; Flower-like cupric oxide nano particles; Human hairs; Solid-phase microextraction; Sol–gel technology; Water samples