title: Heart Rate Recovery as a Preoperative Test of Perioperative Complication Risk.
abstract: The autonomic nervous system plays important physiologic roles in a variety of organ systems. Autonomic dysfunction has been shown to be predictive of increased mortality in patients with cardiovascular disease. Its importance in patients with chronic respiratory disorders has been described in recent years. Here, we summarize the prognostic value of autonomic dysfunction, as reflected by impaired heart rate recovery (HRR), in patients with chronic respiratory disorders, including chronic obstructive pulmonary disease, interstitial lung disease, and lung cancer. We suggest that HRR may be clinically useful in the preoperative physiologic evaluation, specifically in lung cancer patients being considered for surgery.
authors.affiliation: Pulmonary and Critical Care Medicine Division, University of California, San Diego, La Jolla, California. Electronic address: d5ha@ucsd.edu.
authors.forename: Duc
authors.initials: D
authors.lastname: Ha
authors.affiliation: VA San Diego Healthcare System, San Diego, California; Pulmonary and Critical Care Medicine Division, University of California, San Diego, La Jolla, California.
authors.forename: Mark
authors.initials: M
authors.lastname: Fuster
authors.affiliation: Pulmonary and Critical Care Medicine Division, University of California, San Diego, La Jolla, California.
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Ries
authors.affiliation: Pulmonary and Critical Care Medicine Division, University of California, San Diego, La Jolla, California.
authors.forename: Peter D
authors.initials: PD
authors.lastname: Wagner
authors.affiliation: Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Mazzone
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000503:physiopathology; D002908:Chronic Disease; D015444:Exercise / Q000502:physiology; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007431:Intraoperative Complications / Q000453:epidemiology / Q000503:physiopathology; D017563:Lung Diseases, Interstitial / Q000503:physiopathology; D008175:Lung Neoplasms / Q000503:physiopathology; D010101:Oxygen Consumption / Q000502:physiology; D010275:Parasympathetic Nervous System / Q000503:physiopathology; D059035:Perioperative Period; D011379:Prognosis; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology; D012140:Respiratory Tract Diseases / Q000503:physiopathology*