title: Maxillary Sinus Grafting with Autograft Versus Fresh-Frozen Allograft: A Split-Mouth Evaluation of Bone Volume Dynamics.
abstract: OBJECTIVE
  To compare volumetric changes after sinus augmentation of completely edentulous maxillae with either autogenous or allogeneic fresh-frozen bone particles.
  
  
  METHODS
  This split-mouth study in patients who required bilateral sinus grafting used autograft particles for one sinus and allograft particles for the contralateral sinus. The grafted sinuses were left to heal for 6 months prior to implant insertion. All patients underwent four computed tomography scans: prior to augmentation and 1 week, 6 months, and 12 months after grafting. Computer software was used to analyze bone graft volume in each scan.
  
  
  RESULTS
  Fifteen patients (8 men, 7 women) with a mean age of 54 ± 5 years (range, 48 to 60 years) took part and underwent 30 sinus augmentation procedures. Mean autograft and allograft volumes were not statistically significantly different at each time point (1 week: 2.01 ± 0.43 cm³ vs 2.46 ± 0.79 cm³; 6 months: 1.53 ± 0.49 cm³ vs 1.75 ± 0.64 cm³; and 12 months: 1.38 ± 0.43 cm³ vs 1.59 ± 0.56 cm³, respectively). Mean volumetric reductions of 31.35% and 35.36% (23.9% and 29.9% in the 6 months prior to implant insertion, followed by an additional 9% and 9% in the following 6 months), relative to 1 week postgrafting, were noted for the autograft and allograft groups, respectively, after 12 months.
  
  
  CONCLUSIONS
  On the basis of this split-mouth study of 15 patients, there was no statistically significant volumetric difference after 12 months between the use of autograft or allografts for sinus augmentation. Fresh-frozen bone allograft may serve as an alternative that avoids the morbidity associated with autograft harvesting.
authors.forename: Samuel Porfirio
authors.initials: SP
authors.lastname: Xavier
authors.forename: Erick Ricardo
authors.initials: ER
authors.lastname: Silva
authors.forename: Adrian
authors.initials: A
authors.lastname: Kahn
authors.forename: Liat
authors.initials: L
authors.lastname: Chaushu
authors.forename: Gavriel
authors.initials: G
authors.lastname: Chaushu
mesh_terms: D064591:Allografts / Q000473:pathology / Q000637:transplantation*; D001284:Atrophy; D064592:Autografts / Q000473:pathology / Q000637:transplantation*; D016025:Bone Transplantation / Q000379:methods*; D054893:Cone-Beam Computed Tomography / Q000379:methods; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D008437:Maxilla / Q000473:pathology / Q000601:surgery; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009066:Mouth, Edentulous / Q000601:surgery; D009929:Organ Size; D011446:Prospective Studies; D059546:Sinus Floor Augmentation / Q000379:methods*; D012984:Software
chemical_list: D015921:Dental Implants