title: Dielectric analysis of heterogeneous biological tissues based on mixing rule.
abstract: Thus far, the measurement of dielectric properties of biological tissues has been achieved on the assumption that the biological tissues are homogeneous. In fact, most tissues should be heterogeneous because there are many small structures included in these tissues, such as blood vessel, nerve fiber and so on. When the dielectric properties of these tissues are measured by conventional sensor, the results are not the dielectric properties of tissues but the effective dielectric properties of the mixture. In this paper, the influence of the inclusion in tissues on the measurement of dielectric properties of heterogeneous biological tissues is studied and the analysis of the effective dielectric properties of heterogeneous tissues based on the mixing rule is proposed. When the coaxial probe is used to measure the dielectric properties of tissue, the results are relative to the dielectric properties of inclusion, dielectric properties of background tissue and the effective volume fraction of inclusion. Therefore, the dielectric properties of inclusion could be calculated according to mixing rule, after the effective dielectric properties are measured and the effective volume fraction of inclusion is estimated.
authors.affiliation: College of Science, National University of Defense Technology, Changsha, Hunan 410073, P.R. China.
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
authors.affiliation: College of Electronic Science and Engineering, National University of Defense Technology, Changsha, Hunan 410073, P.R. China.
authors.forename: Peiguo
authors.initials: P
authors.lastname: Liu
authors.affiliation: Faculty of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, 710032, P.R. China.
authors.forename: Xiuzhen
authors.initials: X
authors.lastname: Dong
authors.affiliation: College of Electronic Science and Engineering, National University of Defense Technology, Changsha, Hunan 410073, P.R. China.
authors.forename: Dongming
authors.initials: D
authors.lastname: Zhou
authors.affiliation: Faculty of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, 710032, P.R. China.
authors.forename: Xuetao
authors.initials: X
authors.lastname: Shi
mesh_terms: D000818:Animals; D016880:Anisotropy; D003198:Computer Simulation; D017097:Electric Impedance; D006801:Humans; D008954:Models, Biological; D009929:Organ Size / Q000502:physiology*; D010992:Plethysmography, Impedance / Q000379:methods*; D013499:Surface Properties
keywords: Dielectric properties; effective volume fraction; heterogeneous biological tissues; mixing rule