title: Degradable vinyl polymers for biomedical applications.
abstract: Vinyl polymers have been the focus of intensive research over the past few decades and are attractive materials owing to their ease of synthesis and their broad diversity of architectures, compositions and functionalities. Their carbon-carbon backbones are extremely resistant to degradation, however, and this property limits their uses. Degradable polymers are an important field of research in polymer science and have been used in a wide range of applications spanning from (nano)medicine to microelectronics and environmental protection. The development of synthetic strategies to enable complete or partial degradation of vinyl polymers is, therefore, of great importance because it will offer new opportunities for the application of these materials. This Review captures the most recent and promising approaches to the design of degradable vinyl polymers and discusses the potential of these materials for biomedical applications.
authors.affiliation: Institut Galien Paris-Sud, CNRS UMR 8612, Univ Paris-Sud, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
authors.forename: Vianney
authors.initials: V
authors.lastname: Delplace
authors.affiliation: Institut Galien Paris-Sud, CNRS UMR 8612, Univ Paris-Sud, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, F-92296 Châtenay-Malabry cedex, France.
authors.forename: Julien
authors.initials: J
authors.lastname: Nicolas
mesh_terms: D001672:Biocompatible Materials; D011108:Polymers / Q000378:metabolism* / Q000627:therapeutic use*; D014753:Vinyl Compounds / Q000378:metabolism* / Q000627:therapeutic use*
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D014753:Vinyl Compounds