title: Association between activities related to routes of infection and clinical manifestations of melioidosis.
abstract: We sought associations between route of infection by Burkholderia pseudomallei and clinical manifestations in 330 cases of melioidosis in northeast Thailand using bivariate multivariable logistic regression models. Activities related to skin inoculation were negatively associated with bacteraemia, activities related to ingestion were associated with bacteraemia, and activities related to inhalation were associated with pneumonia. Our study suggests that route of infection is one of the factors related to clinical manifestations of melioidosis.
authors.affiliation: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
authors.forename: C
authors.initials: C
authors.lastname: Lim
authors.affiliation: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK; London School of Hygiene and Tropical Medicine, London, UK.
authors.forename: S J
authors.initials: SJ
authors.lastname: Peacock
authors.affiliation: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. Electronic address: direk@tropmedres.ac.
authors.forename: D
authors.initials: D
authors.lastname: Limmathurotsakul
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016957:Burkholderia pseudomallei / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000473:pathology*; D008875:Middle Aged; D013785:Thailand
keywords: Bacteraemia; Burkholderia pseudomallei; ingestion; inhalation; inoculation; melioidosis; pneumonia