title: Blood-Borne Candidatus Borrelia algerica in a Patient with Prolonged Fever in Oran, Algeria.
abstract: To improve the knowledge base of Borrelia in north Africa, we tested 257 blood samples collected from febrile patients in Oran, Algeria, between January and December 2012 for Borrelia species using flagellin gene polymerase chain reaction sequencing. A sequence indicative of a new Borrelia sp. named Candidatus Borrelia algerica was detected in one blood sample. Further multispacer sequence typing indicated this Borrelia sp. had 97% similarity with Borrelia crocidurae, Borrelia duttonii, and Borrelia recurrentis. In silico comparison of Candidatus B. algerica spacer sequences with those of Borrelia hispanica and Borrelia garinii revealed 94% and 89% similarity, respectively. Candidatus B. algerica is a new relapsing fever Borrelia sp. detected in Oran. Further studies may help predict its epidemiological importance.
authors.affiliation: Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), UMR 6236, CNRS 7278, IRD 198, INSERM 1095, IFR 48, Méditerranée Infection, Faculté de Médecine, Aix-Marseille Université, Marseille, France; Service des Maladies Infectieuses, Centre Hospitalo-Universitaire d'Oran, Oran, Algeria.
authors.forename: Aurélien
authors.initials: A
authors.lastname: Fotso Fotso
authors.affiliation: Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), UMR 6236, CNRS 7278, IRD 198, INSERM 1095, IFR 48, Méditerranée Infection, Faculté de Médecine, Aix-Marseille Université, Marseille, France; Service des Maladies Infectieuses, Centre Hospitalo-Universitaire d'Oran, Oran, Algeria angelotasmanos@msn.com.
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Angelakis
authors.affiliation: Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), UMR 6236, CNRS 7278, IRD 198, INSERM 1095, IFR 48, Méditerranée Infection, Faculté de Médecine, Aix-Marseille Université, Marseille, France; Service des Maladies Infectieuses, Centre Hospitalo-Universitaire d'Oran, Oran, Algeria.
authors.forename: Nadjet
authors.initials: N
authors.lastname: Mouffok
authors.affiliation: Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), UMR 6236, CNRS 7278, IRD 198, INSERM 1095, IFR 48, Méditerranée Infection, Faculté de Médecine, Aix-Marseille Université, Marseille, France; Service des Maladies Infectieuses, Centre Hospitalo-Universitaire d'Oran, Oran, Algeria.
authors.forename: Michel
authors.initials: M
authors.lastname: Drancourt
authors.affiliation: Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes (URMITE), UMR 6236, CNRS 7278, IRD 198, INSERM 1095, IFR 48, Méditerranée Infection, Faculté de Médecine, Aix-Marseille Université, Marseille, France; Service des Maladies Infectieuses, Centre Hospitalo-Universitaire d'Oran, Oran, Algeria.
authors.forename: Didier
authors.initials: D
authors.lastname: Raoult
mesh_terms: D000462:Algeria / Q000453:epidemiology; D001483:Base Sequence; D001898:Borrelia / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D017931:DNA Primers / Q000235:genetics; D004269:DNA, Bacterial / Q000097:blood / Q000737:chemistry / Q000235:genetics; D021901:DNA, Intergenic / Q000737:chemistry; D005408:Flagellin / Q000235:genetics; D005843:Geography; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012061:Relapsing Fever / Q000453:epidemiology* / Q000382:microbiology*; D017422:Sequence Analysis, DNA
chemical_list: D017931:DNA Primers; D004269:DNA, Bacterial; D021901:DNA, Intergenic; D005408:Flagellin