title: In vivo dual-modality photoacoustic and optical coherence tomography imaging of human dermatological pathologies.
abstract: Vascular abnormalities serve as a key indicator for many skin diseases. Currently available methods in dermatology such as histopathology and dermatoscopy analyze underlying vasculature in human skin but are either invasive, time-consuming, and laborious or incapable of providing 3D images. In this work, we applied for the first time dual-modality photoacoustic and optical coherence tomography that provides complementary information about tissue morphology and vasculature of patients with different types of dermatitis. Its noninvasiveness and relatively short imaging time and the wide range of diseases that it can detect prove the merits of the dual-modality imaging system and show the great potential of its clinical use in the future.
authors.affiliation: Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH 4L, Währinger Gürtel 18-20, Vienna 1090, Austria.
authors.forename: Behrooz
authors.initials: B
authors.lastname: Zabihian
authors.affiliation: Department of Dermatology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria.
authors.forename: Jessika
authors.initials: J
authors.lastname: Weingast
authors.affiliation: Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH 4L, Währinger Gürtel 18-20, Vienna 1090, Austria.
authors.forename: Mengyang
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department of Medical Physics & Biomedical Engineering, University College London, Gower Street, London, UK.
authors.forename: Edward
authors.initials: E
authors.lastname: Zhang
authors.affiliation: Department of Medical Physics & Biomedical Engineering, University College London, Gower Street, London, UK.
authors.forename: Paul
authors.initials: P
authors.lastname: Beard
authors.affiliation: Department of Dermatology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria.
authors.forename: Hubert
authors.initials: H
authors.lastname: Pehamberger
authors.affiliation: Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH 4L, Währinger Gürtel 18-20, Vienna 1090, Austria.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Drexler
authors.affiliation: Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, AKH 4L, Währinger Gürtel 18-20, Vienna 1090, Austria.
authors.forename: Boris
authors.initials: B
authors.lastname: Hermann
keywords: (170.1870) Dermatology; (170.3880) Medical and biological imaging; (170.4500) Optical coherence tomography; (170.5120) Photoacoustic imaging