title: A new method to accurately assess post-laser-surgery refractive changes with the intrinsic corneal power changes.
abstract: To evaluate the ability of assessing the refractive change induced by myopic laser surgery using the intrinsic data, obtained from a reference intrinsic to the cornea. Twenty-nine eyes with laser in situ keratomileusis for myopia were included in the study. Statistical analyses were performed to determine the relationship between refractive changes and two kinds of corneal power: KIP_value (obtained by keratometric index of 1.3375 and radius of curvature) and RIP_value (obtained by real corneal refraction index of 1.376 and radius of curvature). The comparisons were made between results given by intrinsic data and Pentacam HR. Preoperatively, the intrinsic radii of curvature are significantly less (p≪0.001) than those from Pentacam HR, while the intrinsic radii of curvature are significantly larger (p≪0.001) after surgery. The corneal power changes given by Pentacam HR always underestimate the refractive changes. However, the intrinsic data generally reduce the discrepancies between the corneal power and the refractive changes. The intrinsic KIP_value correlated best with the refractive changes at the corneal plane (p≪0.001) with a prediction error as low as 1.51%. The use of intrinsic data of the cornea can possibly provide an accurate estimation of surgically induced refractive changes.
authors.affiliation: Key Laboratory of Optical Information Science and Technology, Ministry of Education, Institute of Modern Optics, Nankai University, Weijin Rd. 94, Tianjin, 300071, P.R. China.
authors.forename: Yongji
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Key Laboratory of Optical Information Science and Technology, Ministry of Education, Institute of Modern Optics, Nankai University, Weijin Rd. 94, Tianjin, 300071, P.R. China.
authors.forename: Zhaoqi
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Tianjin Eye Hospital & Eye Institute, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Medical University, Tianjin 300020, P.R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D003198:Computer Simulation; D019781:Corneal Topography / Q000379:methods*; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D008954:Models, Biological; D009216:Myopia / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery*; D012029:Refraction, Ocular; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
keywords: Corneal power changes; intrinsic data; refractive changes