title: Long term follow-up after endovascular brachytherapy of femoro-popliteal arteries.
abstract: To perform a long term follow-up after endovascular brachytherapy (EVBT) and balloon angioplasty (PTA) regarding vessel patency and diameter. EVBT had been successfully used to decrease restenosis in short term, but long term data are lacking. Participants of a randomized study comparing EVBT and balloon angioplasty alone were invited for follow-up examination ten years after intervention. Using a standardized protocol measurement of the patency and vessel diameter was performed of femoral and popliteal arteries. 44 patients were included, 21 had been treated with EVBT and 23 had received PTA alone. Target lesion patency was similar between the two groups (90.5% vs. 87.0%). Vessel diameter of the target lesion was significantly greater in the EVBT group (6.4 mm, range 3.9-9.9) compared to the controls (5.0 mm, range 3.1-7.4; p = 0.002). Ten years after EVBT of femoro-popliteal arteries vessel diameter is significantly increased whereas patency rate is not different compared to angioplasty alone.
authors.affiliation: University Hospital Zurich, Clinic for Angiology and University Zurich, Zurich, Switzerland.
authors.forename: Christoph
authors.initials: C
authors.lastname: Thalhammer
authors.affiliation: University Hospital Zurich, Clinic for Angiology and University Zurich, Zurich, Switzerland.
authors.forename: Elena
authors.initials: E
authors.lastname: Alvarez
authors.affiliation: University Hospital Zurich, Clinic for Angiology and University Zurich, Zurich, Switzerland.
authors.forename: Marc
authors.initials: M
authors.lastname: Husmann
authors.affiliation: University Hospital Basel, Clinic for Angiology Basel, Switzerland.
authors.forename: Daniel
authors.initials: D
authors.lastname: Staub
authors.affiliation: University Hospital Basel, Clinic for Angiology Basel, Switzerland.
authors.forename: Mathias
authors.initials: M
authors.lastname: Kaspar
authors.affiliation: University Hospital Basel, Clinic for Angiology Basel, Switzerland.
authors.forename: Markus
authors.initials: M
authors.lastname: Aschwanden
authors.affiliation: University Hospital Zurich, Clinic for Angiology and University Zurich, Zurich, Switzerland.
authors.forename: Beatrice R
authors.initials: BR
authors.lastname: Amann-Vesti
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon; D057510:Endovascular Procedures; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011150:Popliteal Artery / Q000000981:diagnostic imaging / Q000601:surgery*; D016037:Single-Blind Method; D014463:Ultrasonography; D014654:Vascular Patency
keywords: Endovascular brachytherapy; aneurysm; duplex sonography; femoro-popliteal artery; long term follow-up; peripheral artery disease