title: A challenging case of invasive pulmonary aspergillosis after near-drowning: a case report and literature review.
abstract: Near-drowning, a relatively common event, is often complicated by subsequent pneumonia. While endogenous and exogenous bacteria are typical pathogens, rarely fungi are as well. We report a complicated case of invasive pulmonary aspergillosis in a 30-year-old man after a near-drowning event. We also review the medical literature for similar cases. All cases of invasive pulmonary aspergillosis after near-drowning reported in the literature involveAspergillus fumigatus. The majority of cases involved submersion in stagnant water after a motor vehicle accident (MVA). Treatment varied considerably, with amphotericin B used in the majority of cases. Morbidity was considerable with prolonged hospitalization occurring in every case, and mortality occurring in fifty percent of the reported cases. Although a rare complication of near-drowning, invasive pulmonary aspergillosis can occur and lead to significant morbidity and mortality. After near-drowningA. fumigatusisolated from the respiratory tract should be assumed to be a true pathogen and treated accordingly.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, the University of California, San Diego.
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Jenks
authors.affiliation: Division of Infectious Diseases, Department of Medicine, the University of California, San Diego.
authors.forename: Michael
authors.initials: M
authors.lastname: Preziosi
keywords: Aspergillus fumigatus; invasive pulmonary aspergillosis; near-drowning