title: Ophthalmic artery blood flow parameters in pseudoexfoliation glaucoma.
abstract: OBJECTIVE
  To investigate orbital flow parameters of ophthalmic artery (OA) in patients with pseudoexfoliation glaucoma (XFG) by ultrasonography.
  
  
  METHODS
  This case-control study included 38 patients with XFG and 32 healthy control subjects. Color Doppler imaging was performed to evaluate orbital flow parameters of OA. Receiver operating characteristic analyses were performed to define the best cutoff value.
  
  
  RESULTS
  In the XFG group, decreased peak systolic velocity (p = 0.114), end diastolic velocity (p = 0.002), and increased resistivity index (RI) (p&lt;0.001) at OA compared to healthy controls were observed. A cutoff value 0.72 for OA RI was found to have a sensitivity of 66% and specificity of 94%.
  
  
  CONCLUSIONS
  The results support the findings of increased vascular resistance in OA XFG. High sensitivity and specificity obtained for OA RI may be useful in evaluation of future therapeutic vascular agents.
authors.affiliation: Department of Ophthalmology, Adnan Menderes University, Aydın - Turkey.
authors.forename: Tolga
authors.initials: T
authors.lastname: Kocaturk
authors.affiliation: Bergama Government Hospital, Izmir - Turkey.
authors.forename: Isil
authors.initials: I
authors.lastname: Isikligil
authors.affiliation: Akhisar Private Dogus Hospital, Manisa - Turkey.
authors.forename: Burcin
authors.initials: B
authors.lastname: Uz
authors.affiliation: Department of Ophthalmology, Adnan Menderes University, Aydın - Turkey.
authors.forename: Volkan
authors.initials: V
authors.lastname: Dayanir
authors.affiliation: Department of Radiology, Adnan Menderes University, Aydın - Turkey.
authors.forename: Yelda O
authors.initials: YO
authors.lastname: Dayanir
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D017889:Exfoliation Syndrome / Q000503:physiopathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009880:Ophthalmic Artery / Q000502:physiology*; D012372:ROC Curve; D012039:Regional Blood Flow; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color; D014792:Visual Acuity / Q000502:physiology