title: [Relationship between serum zinc levels and attention deficit hyperactivity disorder in children].
abstract: OBJECTIVE
  To study the possible relationship between serum zinc levels and attention deficit hyperactivity disorder (ADHD) in Chinese children.
  
  
  METHODS
  Following a systematic search for case-control studies on the serum zinc levels in Chinese children with ADHD published between 2000 and 2015, a Meta analysis was conducted using Stata 12.0 software.
  
  
  RESULTS
  A total of 17 studies, including 2 177 children with ADHD and 2 900 normal children, were enrolled. The Meta analysis showed that serum zinc levels in children with ADHD were lower than normal children (SMD= -1.33; 95%CI: -2.22, -0.44; P=0.003). The sensitivity analysis indicated that the results were reliable. Eggerγs test did not find the existence of publication bias.
  
  
  CONCLUSIONS
  Serum zinc levels may be associated with susceptibility to ADHD in children.
authors.affiliation: Department of Epidemiology, Public Health School of Xuzhou Medical College, Xuzhou, Jiangsu 221000, China. sunguixiang1974@163.com.
authors.forename: Gui-Xiang
authors.initials: GX
authors.lastname: Sun
authors.forename: Bing-Hua
authors.initials: BH
authors.lastname: Wang
authors.forename: Ya-Feng
authors.initials: YF
authors.lastname: Zhang
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000097:blood; D016022:Case-Control Studies; D002648:Child; D006801:Humans; D015032:Zinc / Q000097:blood*
chemical_list: D015032:Zinc