title: Fluorescent supramolecular polypseudorotaxane architectures with Ru(II)/tri(bipyridine) centers as multifunctional DNA reagents.
abstract: A water-soluble supramolecular polypseudorotaxane was prepared via the host-guest interaction of cucurbit[8]uril and the Ru(bpy)3 complex with bis-naphthalene groups. By employing the intrinsic properties of the Ru(bpy)3 complex, the linear polypseudorotaxane can induce DNA condensation, be used as an inhibitor for DNA cleavage enzymes, and trace the translocation of DNA into 293T cells efficiently.
authors.affiliation: Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, P. R. China. hyzhang@nankai.edu.cn.
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, P. R. China. hyzhang@nankai.edu.cn and Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, P. R. China. yuliu@nankai.edu.cn.
authors.forename: Heng-Yi
authors.initials: HY
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, P. R. China. hyzhang@nankai.edu.cn.
authors.forename: Yu-Hui
authors.initials: YH
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, P. R. China. hyzhang@nankai.edu.cn and Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, P. R. China. yuliu@nankai.edu.cn.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
mesh_terms: D015082:2,2'-Dipyridyl / Q000737:chemistry*; D056831:Coordination Complexes / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D004587:Electrophoresis, Agar Gel; D005456:Fluorescent Dyes / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D015394:Molecular Structure; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D043862:Rotaxanes / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D012995:Solubility; D014867:Water / Q000737:chemistry
chemical_list: D056831:Coordination Complexes; D005456:Fluorescent Dyes; D011108:Polymers; D043862:Rotaxanes; D014867:Water; D015082:2,2'-Dipyridyl; D012428:Ruthenium; D004247:DNA