title: Noninfiltrating Adenocarcinoma of the Lung Causing ST-Segment Elevation.
abstract: ST-segment-elevation myocardial infarction is a leading cause of cardiovascular morbidity and death. We describe the case of a 51-year-old woman with advanced adenocarcinoma of the lung who presented with ST-segment elevation in the presence of an extracardiac lung mass but no objective evidence of myocardial ischemia or pericardial involvement. After the patient died of hypoxic respiratory failure, autopsy findings confirmed normal-appearing pericardium and myocardium, and mild-to-moderate atherosclerosis in the coronary arteries. A 4.5 × 4-cm extracardiac left hilar lung mass was confirmed to be poorly differentiated adenocarcinoma of the lung adjacent to the myocardium. The persistent current of injury that had been detected electrocardiographically was thought to occur from direct myocardial compression. ST-segment elevations secondary to direct mass contact on the myocardium should be considered in patients who have a malignancy and ST-segment elevation.
authors.forename: Shenil
authors.initials: S
authors.lastname: Shah
authors.forename: Bimal
authors.initials: B
authors.lastname: Padaliya
authors.forename: Sri Krishna Madan
authors.initials: SK
authors.lastname: Mohan
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D000077192:Adenocarcinoma of Lung; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000209:etiology*; D001344:Autopsy; D003937:Diagnosis, Differential; D004562:Electrocardiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed
keywords: Arrhythmias, cardiac/diagnosis; diagnosis, differential; electrocardiography; lung neoplasms/complications/pathology; myocardial infarction/classification