title: Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers.
abstract: Purified Shilajit, an Ayurvedic rasayana, was evaluated in healthy volunteers of age between 45 and 55 years for its effect on male androgenic hormone viz. testosterone in a randomised, double-blind, placebo-controlled clinical study at a dose of 250 mg twice a day. Treatment with Shilajit for consecutive 90 days revealed that it has significantly (P < 0.05) increased total testosterone, free testosterone and dehydroepiandrosterone (DHEAS) compared with placebo. Gonadotropic hormones (LH and FSH) levels were well maintained.
authors.affiliation: Research Unit, Department of Health and Family Welfare, J. B. Roy State Ayurvedic Medical College and Hospital, Government of West Bengal, The West Bengal University of Health Sciences, Kolkata, India.
authors.forename: S
authors.initials: S
authors.lastname: Pandit
authors.affiliation: Research Unit, Department of Health and Family Welfare, J. B. Roy State Ayurvedic Medical College and Hospital, Government of West Bengal, The West Bengal University of Health Sciences, Kolkata, India.
authors.forename: S
authors.initials: S
authors.lastname: Biswas
authors.affiliation: Research Unit, Department of Health and Family Welfare, J. B. Roy State Ayurvedic Medical College and Hospital, Government of West Bengal, The West Bengal University of Health Sciences, Kolkata, India.
authors.forename: U
authors.initials: U
authors.lastname: Jana
authors.affiliation: Research Unit, Department of Health and Family Welfare, J. B. Roy State Ayurvedic Medical College and Hospital, Government of West Bengal, The West Bengal University of Health Sciences, Kolkata, India.
authors.forename: R K
authors.initials: RK
authors.lastname: De
authors.affiliation: Research Unit, Department of Health and Family Welfare, J. B. Roy State Ayurvedic Medical College and Hospital, Government of West Bengal, The West Bengal University of Health Sciences, Kolkata, India.
authors.forename: S C
authors.initials: SC
authors.lastname: Mukhopadhyay
authors.affiliation: Research Unit, Department of Health and Family Welfare, J. B. Roy State Ayurvedic Medical College and Hospital, Government of West Bengal, The West Bengal University of Health Sciences, Kolkata, India.
authors.forename: T K
authors.identifier: http://orcid.org/0000-0003-1165-2859
authors.initials: TK
authors.lastname: Biswas
mesh_terms: D003687:Dehydroepiandrosterone / Q000097:blood; D004311:Double-Blind Method; D005640:Follicle Stimulating Hormone / Q000097:blood; D064368:Healthy Volunteers; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008515:Medicine, Ayurvedic; D008875:Middle Aged; D008903:Minerals / Q000008:administration & dosage / Q000494:pharmacology*; D012116:Resins, Plant / Q000008:administration & dosage / Q000494:pharmacology*; D013739:Testosterone / Q000097:blood*
chemical_list: D008903:Minerals; D012116:Resins, Plant; C045109:mumie; D013739:Testosterone; D003687:Dehydroepiandrosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
keywords: Clinical; Shilajit; dehydroepiandrosterone; testosterone