title: An overview of platelet indices for evaluating platelet function in children with scorpion envenomation.
abstract: The aim of this study was to assess the correlation between platelet indices and scorpion envenomations (SE). Medical records of 76 children who were hospitalised for scorpion stings in the paediatric intensive care unit (PICU) between February 2013 and November 2013, and 55 healthy children who were similar to the patient group in terms of age and sex, were analysed retrospectively. The leucocyte (WBC), thrombocyte (PLT), plateletcrit (PCT), platelet distribution width (PDW) and mean platelet volume (MPV) values of the 76 children with SE were recorded. These values were compared with the healthy control group. Significantly higher WBC and PDW values were noted in patients with SE in comparison to the controls. Patients with SE had significantly lower mean MPV values compared to the healthy controls (9.03 ± 1.26 compared to 10.43 ± 1.44 fL, respectively; p < 0.001). Although the mean platelet count was slightly elevated in the SE group, no statistically significant difference existed between the two groups (p = 0.097). Furthermore, the mean PCT values in the SE group compared to the control group were slightly decreased, but this decrease was not statistically significant (p = 0.141). A significant inverse correlation existed between the MPV values and the WBC (r = -0.450, p < 0.01) and PLT counts (r = -0.420, p < 0.01). The PLT values were significantly correlated with the PCT values (r = 0.687, p < 0.01). This study demonstrated that SE may lead to several alterations in platelet indices. Significantly lower values of MPV and higher values of PDW were detected in SE patients. However, the increase in the platelet counts and the decrease in the PCT values were not significant.
authors.affiliation: Adiyaman University, School of Medicine, Department of Pediatrics, Adiyaman, Turkey.
authors.forename: Capan
authors.initials: C
authors.lastname: Konca
authors.affiliation: Adiyaman University, School of Medicine, Department of Pediatrics, Adiyaman, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Tekin
authors.affiliation: Adiyaman University, School of Medicine, Department of Pediatrics, Adiyaman, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Colak
authors.affiliation: Adiyaman University, School of Medicine, Department of Statistics, Adiyaman, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Uckardes
authors.affiliation: Adiyaman University, School of Medicine, Department of Pediatrics, Adiyaman, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Turgut
keywords: children; platelet indices; scorpion envenomation