title: Mental health research priorities for Europe.
abstract: Mental and brain disorders represent the greatest health burden to Europe-not only for directly affected individuals, but also for their caregivers and the wider society. They incur substantial economic costs through direct (and indirect) health-care and welfare spending, and via productivity losses, all of which substantially affect European development. Funding for research to mitigate these effects lags far behind the cost of mental and brain disorders to society. Here, we describe a comprehensive, coordinated mental health research agenda for Europe and worldwide. This agenda was based on systematic reviews of published work and consensus decision making by multidisciplinary scientific experts and affected stakeholders (more than 1000 in total): individuals with mental health problems and their families, health-care workers, policy makers, and funders. We generated six priorities that will, over the next 5-10 years, help to close the biggest gaps in mental health research in Europe, and in turn overcome the substantial challenges caused by mental disorders.
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK. Electronic address: til.wykes@kcl.ac.uk.
authors.forename: Til
authors.initials: T
authors.lastname: Wykes
authors.affiliation: Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain; Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain; Universitat de Barcelona, Barcelona, Spain.
authors.forename: Josep Maria
authors.initials: JM
authors.lastname: Haro
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
authors.forename: Stefano R
authors.initials: SR
authors.lastname: Belli
authors.affiliation: Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain; Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain.
authors.forename: Carla
authors.initials: C
authors.lastname: Obradors-Tarragó
authors.affiliation: Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain; Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
authors.forename: Celso
authors.initials: C
authors.lastname: Arango
authors.affiliation: Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain; Department of Psychiatry, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, Universidad Autónoma de Madrid, Madrid, Spain.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Ayuso-Mateos
authors.affiliation: Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary.
authors.forename: István
authors.initials: I
authors.lastname: Bitter
authors.affiliation: Fondation FondaMental, Créteil, France; URC Eco Ile-de-France (AP-HP), Paris, France.
authors.forename: Matthias
authors.initials: M
authors.lastname: Brunn
authors.affiliation: Fondation FondaMental, Créteil, France; URC Eco Ile-de-France (AP-HP), Paris, France; Institut National de la Santé et de la Recherche Médicale (INSERM U955), and Department of Psychiatry, Henri Mondor Hospital, University Paris-Est-Créteil, Creteil, Paris, France.
authors.forename: Karine
authors.initials: K
authors.lastname: Chevreul
authors.affiliation: Institut National de la Santé et de la Recherche Médicale (INSERM U955), and Department of Psychiatry, Henri Mondor Hospital, University Paris-Est-Créteil, Creteil, Paris, France; ECRIN Coordination Office, Paris, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Demotes-Mainard
authors.affiliation: Tilburg University, Tranzo Department, Tilburg, Netherlands; Department of Health Promotion, School of Public Health and Primary Care, Maastricht University, Maastricht, Netherlands.
authors.forename: Iman
authors.initials: I
authors.lastname: Elfeddali
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
authors.forename: Sara
authors.initials: S
authors.lastname: Evans-Lacko
authors.affiliation: Department of Psychiatry, University of Naples SUN, Naples, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Fiorillo
authors.affiliation: The Nordic School of Public Health, Gothenburg, Sweden; National Institute for Health and Welfare, Vaasa, Finland.
authors.forename: Anna K
authors.initials: AK
authors.lastname: Forsman
authors.affiliation: Fondation FondaMental, Créteil, France; URC Eco Ile-de-France (AP-HP), Paris, France.
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Hazo
authors.affiliation: Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, Euron, Maastricht University Medical Centre, Maastricht, Netherlands.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Kuepper
authors.affiliation: Institute of Clinical Psychology and Psychotherapy, and Center for Epidemiology and Longitudinal Studies, Technische Universität Dresden, Dresden, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Knappe
authors.affiliation: Fondation FondaMental, Créteil, France; Institut National de la Santé et de la Recherche Médicale (INSERM U955), and Department of Psychiatry, Henri Mondor Hospital, University Paris-Est-Créteil, Creteil, Paris, France.
authors.forename: Marion
authors.initials: M
authors.lastname: Leboyer
authors.affiliation: University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
authors.forename: Shôn W
authors.initials: SW
authors.lastname: Lewis
authors.affiliation: Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, Euron, Maastricht University Medical Centre, Maastricht, Netherlands.
authors.forename: Donald
authors.initials: D
authors.lastname: Linszen
authors.affiliation: Department of Psychiatry, University of Naples SUN, Naples, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Luciano
authors.affiliation: Department of Psychiatry, University of Naples SUN, Naples, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Maj
authors.affiliation: Personal Social Services Research Unit, LSE Health and Social Care, London School of Economics and Political Science, London, UK.
authors.forename: David
authors.initials: D
authors.lastname: McDaid
authors.affiliation: Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain; Department of Psychiatry, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa, Universidad Autónoma de Madrid, Madrid, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Miret
authors.affiliation: Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary.
authors.forename: Szilvia
authors.initials: S
authors.lastname: Papp
authors.affiliation: Personal Social Services Research Unit, LSE Health and Social Care, London School of Economics and Political Science, London, UK.
authors.forename: A-La
authors.initials: AL
authors.lastname: Park
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
authors.forename: Gunter
authors.initials: G
authors.lastname: Schumann
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
authors.forename: Graham
authors.initials: G
authors.lastname: Thornicroft
authors.affiliation: Tilburg University, Tranzo Department, Tilburg, Netherlands; GGz Breburg, Tilburg, Netherlands.
authors.forename: Christina
authors.initials: C
authors.lastname: van der Feltz-Cornelis
authors.affiliation: Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, Euron, Maastricht University Medical Centre, Maastricht, Netherlands.
authors.forename: Jim
authors.initials: J
authors.lastname: van Os
authors.affiliation: The Nordic School of Public Health, Gothenburg, Sweden; National Institute for Health and Welfare, Vaasa, Finland; Finnish Association for Mental Health, Helsinki, Finland.
authors.forename: Kristian
authors.initials: K
authors.lastname: Wahlbeck
authors.affiliation: Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
authors.forename: Tom
authors.initials: T
authors.lastname: Walker-Tilley
authors.affiliation: Institute of Clinical Psychology and Psychotherapy, and Center for Epidemiology and Longitudinal Studies, Technische Universität Dresden, Dresden, Germany.
authors.forename: Hans-Ulrich
authors.initials: HU
authors.lastname: Wittchen
mesh_terms: D035843:Biomedical Research; D005060:Europe; D006801:Humans; D001523:Mental Disorders / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic; D012106:Research