title: Advanced Imaging of Chiari 1 Malformations.
abstract: Type I Chiari malformations are congenital deformities involving cerebellar tonsillar herniation downward through the foramen magnum. Structurally, greater than 5 mm of tonsillar descent in adults and more than 6 mm in children is consistent with type I Chiari malformations. However, the radiographic severity of the tonsillar descent does not always correlate well with the clinical symptomatology. Advanced imaging can help clinically correlate imaging to symptoms. Specifically, cerebrospinal fluid (CSF) flow abnormalities are seen in patients with type I Chiari malformation. Advanced MRI involving cardiac-gated and phase-contrast MRI affords a view of such CSF flow abnormalities.
authors.affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 1 Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA.
authors.forename: Akbar
authors.initials: A
authors.lastname: Fakhri
authors.affiliation: Department of Pediatric Surgery, University of Texas, Health Science Center at Houston, 6431 Fannin Street, MSB 5.144, Houston, TX 77030, USA; Department of Neurosurgery, University of Texas, Health Science Center at Houston, 6431 Fannin Street, MSB 5.144, Houston, TX 77030, USA.
authors.forename: Manish N
authors.initials: MN
authors.lastname: Shah
authors.affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 1 Barnes Jewish Hospital Plaza, St Louis, MO 63110, USA. Electronic address: goyalm@mir.wustl.edu.
authors.forename: Manu S
authors.initials: MS
authors.lastname: Goyal
mesh_terms: D001139:Arnold-Chiari Malformation / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D001921:Brain / Q000000981:diagnostic imaging*; D002555:Cerebrospinal Fluid / Q000000981:diagnostic imaging; D005539:Foramen Magnum / Q000000981:diagnostic imaging*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D011859:Radiography
keywords: Cerebrospinal fluid flow imaging; Chiari malformation; Cine fast image spin precession; MRI