title: Understanding the Etiology and Prevention of Capsular Contracture: Translating Science into Practice.
abstract: Capsular contracture remains a common and preventable complication of implanted breast prostheses. As our understanding of the pathophysiology continues to develop, it is prudent to reexamine existing beliefs in a contemporary context. This article presents a current summary of clinical and laboratory evidence, expressed as an interaction between potentiating and suppressing factors, and how this understanding can be applied to practice.
authors.affiliation: Department of Plastic, Reconstructive & Maxillofacial Surgery, Faculty of Medicine and Human Sciences, Macquarie University, Suite 301, Level 3, Macquarie University Clinic Macquarie Park, Sydney NSW 2109, Australia.
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Chong
authors.affiliation: Department of Plastic, Reconstructive & Maxillofacial Surgery, Faculty of Medicine and Human Sciences, Macquarie University, Suite 301, Level 3, Macquarie University Clinic Macquarie Park, Sydney NSW 2109, Australia. Electronic address: Anand.deva@mq.edu.au.
authors.forename: Anand K
authors.initials: AK
authors.lastname: Deva
mesh_terms: D019072:Antibiotic Prophylaxis; D001672:Biocompatible Materials / Q000009:adverse effects; D018441:Biofilms; D001940:Breast / Q000382:microbiology / Q000601:surgery; D019928:Breast Implantation / Q000009:adverse effects* / Q000379:methods; D018427:Breast Implants / Q000009:adverse effects*; D004866:Equipment Contamination / Q000517:prevention & control*; D005260:Female; D006801:Humans; D057910:Implant Capsular Contracture / Q000209:etiology* / Q000517:prevention & control* / Q000601:surgery; D011474:Prosthesis Design; D016459:Prosthesis-Related Infections / Q000150:complications* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000150:complications / Q000382:microbiology; D013212:Staphylococcus epidermidis / Q000302:isolation & purification; D013242:Sterilization
chemical_list: D001672:Biocompatible Materials
keywords: Biofilm; Breast augmentation; Capsular contracture; Silicone; Staphylococcus epidermidis