title: Preventing Acute Kidney Injury.
abstract: Epidemiologic studies applying the acute kidney injury (AKI) classification system have confirmed the increasing incidence of AKI in different settings and its association with adverse outcomes. AKI is now a recognized important risk factor for new-onset chronic kidney disease, determining acceleration in progression to end-stage renal disease, leading to poor quality of life, disability, and long-term costs. AKI has been associated with high mortalities; however, it is likely that a significant number of deaths associated with AKI could be avoided. This article reviews the key aspects of the 0by25 initiative and its application in critically ill patients.
authors.affiliation: Department of Medicine, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103, USA; Nephrology Division, University of Sao Paulo, Brazil.
authors.forename: Etienne
authors.initials: E
authors.lastname: Macedo
authors.affiliation: Department of Medicine, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103, USA. Electronic address: rmehta@ucsd.edu.
authors.forename: Ravindra L
authors.initials: RL
authors.lastname: Mehta
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D014943:Global Health; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D009398:Nephrology / Q000193:education; D009937:Organizational Objectives; D017582:Renal Replacement Therapy; D018570:Risk Assessment; D012307:Risk Factors; D012955:Societies, Medical
keywords: Acute kidney injury; Epidemiology; Prevention