title: Possible association between mandibular repositioning device for sleep apnea and osseous lytic lesion with fracture of the coronoid process of the mandible: A case report.
abstract: Mandibular repositioning devices (MRDs) increase the patency of the upper airway by repositioning the mandible forward, resulting in displacement of the oropharyngeal tissues preventing upper airway collapsibility. Mandibular anterior repositioning is counteracted by muscle force from the temporalis muscle. A 39-year-old man had an osteolytic lesion with fracture of the coronoid process of the mandible secondary to wearing a MRD for sleep apnea. Continuous stress generated on the coronoid process temporalis muscle resulted in osteolysis and fracture of the coronoid process on the patient's right side, resulting in swelling and limited ability to open his mouth. The patient was managed with intravenous antibiotics to control the osteomyelitis and surgical debridement, with removal of the coronoid process of the mandible. It is unclear why the fracture only occurred on the right side. Pathologic fracture of the coronoid process due to chronic stress and secondary osteomyelitis is a rare severe complication of treatment for obstructive sleep apnea syndrome with a MRD.
authors.forename: Jimoh Olubanwo
authors.initials: JO
authors.lastname: Agbaje
authors.forename: Ahmed S
authors.initials: AS
authors.lastname: Salem
authors.forename: Ivo
authors.initials: I
authors.lastname: Lambrichts
authors.forename: Marc
authors.initials: M
authors.lastname: Braem
authors.forename: Constantinus
authors.initials: C
authors.lastname: Politis
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000295:instrumentation*; D008337:Mandibular Fractures / Q000209:etiology* / Q000628:therapy*; D009968:Orthodontic Appliances, Removable / Q000009:adverse effects*; D010014:Osteolysis / Q000209:etiology* / Q000628:therapy*; D012891:Sleep Apnea Syndromes / Q000628:therapy*; D013314:Stress, Mechanical
chemical_list: D000900:Anti-Bacterial Agents