title: Monitoring of chronic γ-secretase modulator treatment by serial amyloid-PET.
authors.affiliation: Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Brendel
authors.affiliation: DZNE-German Center for Neurodegenerative Diseases, Munich, Germany.|Laboratory of Neurodegeneration, International Institute of Molecular and Cell Biology, Warsaw, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Jaworska
authors.affiliation: DZNE-German Center for Neurodegenerative Diseases, Munich, Germany.|Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Herms
authors.affiliation: Biomedical Center (BMC), Ludwig-Maximilians-University of Munich, Munich, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Trambauer
authors.affiliation: Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Rötzer
authors.affiliation: Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.
authors.forename: F-J
authors.initials: FJ
authors.lastname: Gildehaus
authors.affiliation: Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Carlsen
authors.affiliation: Department of Psychiatry, University of Oslo, Oslo, Norway.
authors.forename: P
authors.initials: P
authors.lastname: Cumming
authors.affiliation: Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Bylund
authors.affiliation: Roche Pharma Research and Early Development, Small Molecule Research, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland.
authors.forename: T
authors.initials: T
authors.lastname: Luebbers
authors.affiliation: Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.|Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Bartenstein
authors.affiliation: DZNE-German Center for Neurodegenerative Diseases, Munich, Germany.|Biomedical Center (BMC), Ludwig-Maximilians-University of Munich, Munich, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Steiner
authors.affiliation: DZNE-German Center for Neurodegenerative Diseases, Munich, Germany.|Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.|Biomedical Center (BMC), Ludwig-Maximilians-University of Munich, Munich, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Haass
authors.affiliation: Roche Pharma Research and Early Development, Neuroscience Discovery, Roche Innovation Center Basel, F. Hoffmann-La Roche, Basel, Switzerland.
authors.forename: K
authors.initials: K
authors.lastname: Baumann
authors.affiliation: Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.|Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Rominger
mesh_terms: D053829:Amyloid Precursor Protein Secretases / Q000032:analysis* / Q000037:antagonists & inhibitors / Q000378:metabolism; D016229:Amyloid beta-Peptides / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging* / Q000201:enzymology*; D051379:Mice; D049268:Positron-Emission Tomography / Q000379:methods*
chemical_list: D016229:Amyloid beta-Peptides; D053829:Amyloid Precursor Protein Secretases