title: Phytochemical analysis of Hibiscus caesius using high performance liquid chromatography coupled with mass spectrometry.
abstract: Various species in genus Hibiscus are traditionally known for their therapeutic attributes. The present study focused on the phytochemical analysis of a rather unexplored species Hibiscus caesius (H. caesius), using high-pressure liquid chromatography coupled with mass spectrometry (HPLC-MS). The analysis revealed five major compounds in the aqueous extract, viz. vanillic acid, protocatechoic acid, quercetin, quercetin glucoside and apigenin, being reported for the first time in H. caesius. Literature suggests that these compounds have important pharmacological traits such as anti-cancer, anti-inflammatory, anti-bacterial and hepatoprotective etc. however, this requires further pharmacological investigations at in vitro and in vivo scale. The above study concluded the medicinal potential of H. caesius.
authors.affiliation: Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
authors.forename: Quratul
authors.initials: Q
authors.lastname: Ain
authors.affiliation: Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
authors.forename: Muhammad Na
authors.initials: MN
authors.lastname: Naveed
authors.affiliation: Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan.
authors.forename: Abdul Samad
authors.initials: AS
authors.lastname: Mumtaz
authors.affiliation: Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Farman
authors.affiliation: National Institute for Genomics and Advanced Biotechnology (NIGAB), National Agricultural Research Centre (NARC), Park Road, Islamabad, Pakistan.
authors.forename: Iftikhar
authors.initials: I
authors.lastname: Ahmed
authors.affiliation: Graduate School of Agricultural and Life Science, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, Japan.
authors.forename: Nauman
authors.initials: N
authors.lastname: Khalid
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D031584:Hibiscus / Q000737:chemistry*; D013058:Mass Spectrometry