title: Macrocytosis and sudden sensorineural hearing loss: a case report.
abstract: BACKGROUND
  Although other blood dyscrasias are known to cause sudden sensorineural hearing loss, macrocytosis has not previously been implicated in the absence of another causative agent.
  
  
  METHODS
  We present a case of bilateral sequential sudden sensorineural hearing loss in a patient with significant macrocytosis (mean corpuscular volume at presentation 124 fl) secondary to alcohol-induced liver dysfunction.
  
  
  CONCLUSIONS
  A possible pathophysiological mechanism linking macrocytosis and sudden sensorineural hearing loss was identified, suggesting areas for further investigation.
authors.affiliation: Department of Otolaryngology,Ulster Hospital,Belfast,Northern Ireland,UK.
authors.forename: A E L
authors.initials: AE
authors.lastname: McMurran
authors.affiliation: Department of Otolaryngology,Ulster Hospital,Belfast,Northern Ireland,UK.
authors.forename: R A
authors.initials: RA
authors.lastname: Adair
mesh_terms: D000437:Alcoholism / Q000150:complications; D000748:Anemia, Macrocytic / Q000150:complications*; D019929:Cochlear Implantation / Q000379:methods; D005260:Female; D006312:Hearing Loss, Bilateral / Q000175:diagnosis / Q000209:etiology*; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D003639:Hearing Loss, Sudden / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008875:Middle Aged; D012307:Risk Factors; D016896:Treatment Outcome
keywords: Hearing Loss; Sensorineural; Sudden