title: Antidiabetic potential of some less commonly used plants in traditional medicinal systems of India and Nigeria.
abstract: The incidence of diabetes mellitus continue to rise annually all over the world with India and Nigeria having recorded cases of 65.1 and 3.9 million respectively in 2013 and expected to increase by a large amount in 2035. Hyperglycemia is a pre-condition for the development of diabetic complications and is accompanied by an increase in the production of free radicals. The present available treatment option for diabetes like sulfonylurea, metformin and alpha-glucosidase are restricted by their limited actions, secondary failure rates, and side-effects; and unaffordable to the majority of the population. Hence, the need to screen for more medicinal plants with antidiabetic ability due to the fact that plants are; biodegradable, safe and cheap with fewer side-effects. In this review article, we have presented the current status of diabetes in India and Nigeria and the role of some less commonly used medicinal plants from both countries that have antidiabetic potential.
authors.affiliation: Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, India.
authors.forename: Abubakar
authors.initials: A
authors.lastname: Mohammed
authors.affiliation: Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, India.
authors.forename: Dileep
authors.initials: D
authors.lastname: Kumar
authors.affiliation: Department of Biochemistry, University of Allahabad, Allahabad, Uttar Pradesh, India.
authors.forename: Syed Ibrahim
authors.initials: SI
authors.lastname: Rizvi
keywords: Antidiabetic plants; diabetes; hypoglycaemic activity; medicinal plants; oxidative stress