title: An Epidemiological Study of Risk Factors of Thyroid Nodule and Goiter in Chinese Women.
abstract: Thyroid nodule (TN) and goiter are two common disorders of the thyroid. Despite their benign nature, both conditions can be associated with multiple pathologic conditions including thyroid cancer. In this study, we conducted a large-scale epidemiological study in Chinese women to identify the risk factors implicated in the occurrence of TN and goiter. We analyzed demographic data, lifestyle, medical history, body height, weight, waist circumference, body mass index (BMI), blood pressure, serum glucose and lipids. In addition, thyroid ultrasonography was performed for all subjects. Our results showed that age, menopause, waist circumference, BMI, hypertension, dyslipidemia, and hyperglycemia were associated with both TN and goiter. Furthermore, we found that the prevalence of TN was significantly affected by the medical management of hypertension. Our study suggests that postmenopausal Chinese women with advanced age, obesity, diabetes, and hypertension have an increased awareness of thyroid examination in the annual physical check. Conversely, patients with TN and goiter of the same population may have a higher incidence of age- and obesity-related metabolic disorders.
authors.affiliation: Department of Endocrinology, Chinese People's Liberation Army (PLA)General Hospital, 28 Fu Xing Road, Beijing 100853, China. zhenglei79541@163.com.|Department of Endocrinology, First Affiliated Hospital of Chinese People's Liberation Army General Hospital, 51 Fucheng Road, Beijing 100048,China. zhenglei79541@163.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Zheng
authors.affiliation: Department of Endocrinology, Chinese People's Liberation Army (PLA)General Hospital, 28 Fu Xing Road, Beijing 100853, China. yanwenhua301@163.com.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Yan
authors.affiliation: Department of Interventional Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fu Xing Road, Beijing 100853, China. kongyue79541@163.com.|Department of Ultrasound, Beijing Shijitan Hospital, The 9th Clinical Medical College of Peking University,10 Tieyi Road, Yangfangdian, Haidian District, Beijing 100038, China. kongyue79541@163.com.
authors.forename: Yue
authors.initials: Y
authors.lastname: Kong
authors.affiliation: Department of Interventional Ultrasound, Chinese People's Liberation Army General Hospital, 28 Fu Xing Road, Beijing 100853, China. liangping301@hotmail.com.
authors.forename: Ping
authors.initials: P
authors.lastname: Liang
authors.affiliation: Department of Endocrinology, Chinese People's Liberation Army (PLA)General Hospital, 28 Fu Xing Road, Beijing 100853, China. muyiming@301hospital.com.cn.
authors.forename: Yiming
authors.initials: Y
authors.lastname: Mu
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People / Q000208:ethnology*; D001794:Blood Pressure; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002681:China / Q000453:epidemiology; D016021:Epidemiologic Studies; D005260:Female; D006042:Goiter / Q000453:epidemiology*; D006801:Humans; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D016606:Thyroid Nodule / Q000453:epidemiology*; D055105:Waist Circumference; D016387:Women's Health
chemical_list: D008055:Lipids
keywords: epidemiology; metabolic syndrome; prevalence; risk factor