title: Proliferative and Migration Activity of JEG-3 Trophoblast Cell Line in the Presence of Cytokines.
abstract: TNFα inhibited proliferation and did not inhibit migration JEG-3 trophoblast cells, IL-1β stimulated both cell proliferation and migration, IL-6 and IL-8 stimulated only cell migration, IFNγ has either stimulating or inhibitory effect on proliferation of trophoblast cells depending on its concentration. Cytokines IL-10 and IL-4 stimulated only migration of trophoblast cells. VEGF, PlGF, and TGFβ stimulated both proliferation and migration, and bFGF only migration of trophoblast cells.
authors.affiliation: D. O. Ott Research Institute of Obstetrics and Gynecology, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia. falcojugger@yandex.ru.
authors.forename: D I
authors.initials: DI
authors.lastname: Sokolov
authors.affiliation: D. O. Ott Research Institute of Obstetrics and Gynecology, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia.
authors.forename: K N
authors.initials: KN
authors.lastname: Furaeva
authors.affiliation: D. O. Ott Research Institute of Obstetrics and Gynecology, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia.
authors.forename: O I
authors.initials: OI
authors.lastname: Stepanova
authors.affiliation: D. O. Ott Research Institute of Obstetrics and Gynecology, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Sel'kov
mesh_terms: D002460:Cell Line; D002465:Cell Movement; D049109:Cell Proliferation; D016207:Cytokines / Q000502:physiology*; D006801:Humans; D014327:Trophoblasts / Q000502:physiology*
chemical_list: D016207:Cytokines
keywords: cytokines; migration; proliferation; trophoblast