title: A biphasic mercury-ion sensor: exploiting microfluidics to make simple anilines competitive ligands.
abstract: Combining the molecular wire effect with a biphasic sensing approach (analyte in water, sensor-dye in 2-methyltetrahydrofuran) and a microfluidic flow setup leads to the construction of a mercury-sensitive module. We so instantaneously detect Hg(2+) ions in water at a 500 μM concentration. The sensor, conjugated non-water soluble polymer 1 (XFPF), merely supports dibutylaniline substituents as binding units. Yet, selective and sensitive detection of Hg(2+) -ions is achieved in water. The enhancement in sensory response, when comparing the reference compound 2 to that of 1 in a biphasic system in a microfluidic chip is >10(3) . By manipulation of the structure of 1, further powerful sensor systems should be easily achieved.
authors.affiliation: Organisch Chemisches Institut and Centre for Advanced Materials (CAM), Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 225 and 270, 69120 Heidelberg (Germany).
authors.forename: Martin
authors.initials: M
authors.lastname: Petzoldt
authors.affiliation: InnovationLab GmbH, Speyerer Straße 4, 69117 Heidelberg (Germany).|Lichttechnisches Institut and Institute of Microstructure Technology, Karlsruhe Institute of Technology, Engesserstr. 13, 76131 Karlsruhe (Germany).
authors.forename: Carsten
authors.initials: C
authors.lastname: Eschenbaum
authors.affiliation: Organisch Chemisches Institut and Centre for Advanced Materials (CAM), Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 225 and 270, 69120 Heidelberg (Germany).
authors.forename: S Thimon
authors.initials: ST
authors.lastname: Schwaebel
authors.affiliation: Organisch Chemisches Institut and Centre for Advanced Materials (CAM), Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 225 and 270, 69120 Heidelberg (Germany).
authors.forename: Kerstin
authors.initials: K
authors.lastname: Broedner
authors.affiliation: InnovationLab GmbH, Speyerer Straße 4, 69117 Heidelberg (Germany).|Lichttechnisches Institut and Institute of Microstructure Technology, Karlsruhe Institute of Technology, Engesserstr. 13, 76131 Karlsruhe (Germany).
authors.forename: Uli
authors.initials: U
authors.lastname: Lemmer
authors.affiliation: Organisch Chemisches Institut and Centre for Advanced Materials (CAM), Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 225 and 270, 69120 Heidelberg (Germany).|InnovationLab GmbH, Speyerer Straße 4, 69117 Heidelberg (Germany).
authors.forename: Manuel
authors.initials: M
authors.lastname: Hamburger
authors.affiliation: Organisch Chemisches Institut and Centre for Advanced Materials (CAM), Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 225 and 270, 69120 Heidelberg (Germany). uwe.bunz@oci.uni-heidelberg.de.
authors.forename: Uwe H F
authors.initials: UH
authors.lastname: Bunz
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D005663:Furans / Q000737:chemistry; D007477:Ions / Q000737:chemistry*; D008024:Ligands; D008628:Mercury / Q000737:chemistry*; D044085:Microfluidics / Q000379:methods; D014867:Water / Q000737:chemistry
chemical_list: D000814:Aniline Compounds; D005663:Furans; D007477:Ions; D008024:Ligands; D014867:Water; C550584:2-methyltetrahydrofuran; D008628:Mercury; C023650:aniline
keywords: 2-methyltetrahydrofuran; biphasic; mercury; microfluidic device; sensors