title: An Association of Chronic Hyperaldosteronism with Medullary Nephrocalcinosis.
abstract: BACKGROUND
  An association between chronic hyperaldosteronism and medullary nephrocalcinosis has rarely been made, with only a handful of cases described in literature.
  
  
  METHODS
  We describe five cases of hyperaldosteronism with a long- standing history in whom associated medullary nephrocalcinosis was established.
  
  
  CONCLUSIONS
  We infer that a chronic hyperaldosteronic status, whether primary or secondary, is a causal factor in the etiopathogenesis of medullary nephrocalcinosis. This article illustrates and summarizes various postulated theories that support our proposed association between hyperaldosteronism and nephrocalcinosis. We conclude that chronic hyperaldosteronism should be included as one of the causes of nephrocalcinosis and that our case series emphasizes the need of a well-organized retrospective study to prove it further.
authors.affiliation: Department of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
authors.forename: Kartik
authors.initials: K
authors.lastname: Mittal
authors.affiliation: Department of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
authors.forename: Karan
authors.initials: K
authors.lastname: Anandpara
authors.affiliation: Department of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
authors.forename: Amit K
authors.initials: AK
authors.lastname: Dey
authors.affiliation: Department of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
authors.forename: Rajaram
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Department of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
authors.forename: Hemangini
authors.initials: H
authors.lastname: Thakkar
authors.affiliation: Department of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
authors.forename: Priya
authors.initials: P
authors.lastname: Hira
authors.affiliation: Department of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India.
authors.forename: Hemant
authors.initials: H
authors.lastname: Deshmukh
keywords: Hyperaldosteronism; Hypercalciuria; Nephrocalcinosis