title: Fosaprepitant for the Treatment of Refractory Postoperative Nausea and Vomiting.
abstract: Postoperative nausea and vomiting (PONV) is a debilitating condition that occurs in approximately 30% of patients undergoing general anesthesia. Premedication with 5-HT3 receptor antagonists and glucocorticoids is effective in clinical practice; however, 10% to 20% of patients still develop PONV. Currently, little is known about the treatment of refractory PONV. We present a case that illustrates the use of fosaprepitant for the treatment of refractory postoperative nausea and vomiting.
authors.affiliation: Pharmacist, Department of Pharmacy, Stanford Health Care , Stanford, California .
authors.forename: Linh H
authors.initials: LH
authors.lastname: Tran
authors.affiliation: Pharmacist, Department of Pharmacy, Stanford Health Care , Stanford, California .
authors.forename: Magdalena
authors.initials: M
authors.lastname: Cudny
authors.affiliation: Pharmacist, Department of Pharmacy, Stanford Health Care , Stanford, California .
authors.forename: Dat
authors.initials: D
authors.lastname: Ngo
authors.affiliation: Pharmacist, Department of Pharmacy, Stanford Health Care , Stanford, California .
authors.forename: Samit
authors.initials: S
authors.lastname: Patel
authors.affiliation: Hospitalist & Clinical Instructor, Stanford Health Care , Stanford, California .
authors.forename: Manuel Y
authors.initials: MY
authors.lastname: Lam
keywords: Emend; breakthrough; fosaprepitant; nausea; postoperative; refractory; vomiting