title: Eco-friendly electrochemical lab-on-paper for heavy metal detection.
abstract: A disposable electrochemical lateral flow paper-based sensing device for heavy metal detection is proposed. The quantification of lead and cadmium in aqueous samples is demonstrated in a range from 10 to 100 ppb with a limit of detection of 7 and 11 ppb respectively. Moreover, the platform itself, which is made of paper, served as a sample pretreatment material due to its filtering properties. Real samples, especially in which the matrix is usually turbid and would in principle need a previous filtration, are successfully analyzed. This lab-on-paper device is simple, low cost, easy to fabricate, and portable, being a promising tool for new point-of-care applications in environmental monitoring, public health, and food safety.
authors.affiliation: Nanobioelectronics and Biosensor Group, Institut Catala de Nanociencia y Nanotecnologia (ICN2), Campus de la UAB, Bellaterra, 08193, Barcelona, Spain.
authors.forename: Mariana
authors.initials: M
authors.lastname: Medina-Sánchez
authors.affiliation: Nanobioelectronics and Biosensor Group, Institut Catala de Nanociencia y Nanotecnologia (ICN2), Campus de la UAB, Bellaterra, 08193, Barcelona, Spain.|Inorganic Chemistry Department, Universitat Autonoma de Barcelona (UAB), Campus UAB, Bellaterra, 08193, Barcelona, Spain.
authors.forename: Miquel
authors.initials: M
authors.lastname: Cadevall
authors.affiliation: Inorganic Chemistry Department, Universitat Autonoma de Barcelona (UAB), Campus UAB, Bellaterra, 08193, Barcelona, Spain.
authors.forename: Josep
authors.initials: J
authors.lastname: Ros
authors.affiliation: Nanobioelectronics and Biosensor Group, Institut Catala de Nanociencia y Nanotecnologia (ICN2), Campus de la UAB, Bellaterra, 08193, Barcelona, Spain. arben.merkoci@icn.cat.|ICREA, Institució Catalana de Recerca i Estudis Avançats, 08018, Barcelona, Spain. arben.merkoci@icn.cat.
authors.forename: Arben
authors.initials: A
authors.lastname: Merkoçi
mesh_terms: D002104:Cadmium / Q000032:analysis*; D002413:Cations, Divalent; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods*; D004566:Electrodes; D055772:Green Chemistry Technology; D006801:Humans; D007854:Lead / Q000032:analysis*; D057230:Limit of Detection; D010209:Paper; D019095:Point-of-Care Systems; D012623:Seawater / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D002413:Cations, Divalent; D014874:Water Pollutants, Chemical; D002104:Cadmium; D007854:Lead
keywords: Electrochemical detection; Heavy metals; Lateral flow; Paper microfluidics