title: Perceived reputation of others modulates empathic neural responses.
abstract: Empathy enables us to understand and share the emotional and affective states of another person and plays a key role in social behaviors. The current study investigated whether and how empathic neural responses to pain were modulated by the perceived reputation of others. Action histories reflecting individuals' past cooperation or betrayal actions in the repeated prisoner's dilemma game were introduced as an index of reputation. We assessed brain activity with functional magnetic resonance imaging while the participants observed individuals with a good or bad reputation receiving or not receiving pain. The results indicated that the participants exhibited reduced empathic responses in AI and dACC to the individual who had a bad reputation relative to the one who had a good reputation, suggesting that their empathy for pain was modulated by the perceived reputation of others.
authors.affiliation: Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, School of Psychology and Cognitive Science, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zheng
authors.affiliation: Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China.|Department of Physics, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China.
authors.forename: Qianfeng
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China.|Department of Physics, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China.
authors.forename: Xuemei
authors.initials: X
authors.lastname: Cheng
authors.affiliation: School of Psychology and Cognitive Science, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Li
authors.affiliation: Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China. gyang@phy.ecnu.edu.cn.|Department of Physics, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China. gyang@phy.ecnu.edu.cn.
authors.forename: Guang
authors.initials: G
authors.lastname: Yang
authors.affiliation: School of Psychology and Cognitive Science, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China.
authors.forename: Lining
authors.initials: L
authors.lastname: Sun
authors.affiliation: School of Psychology and Cognitive Science, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Ling
authors.affiliation: Key Laboratory of Brain Functional Genomics, Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, School of Psychology and Cognitive Science, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China. wlkc_xyguo@126.com.|Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China. wlkc_xyguo@126.com.|School of Psychology and Cognitive Science, East China Normal University, North Zhongshan Road 3663, Shanghai, 200062, China. wlkc_xyguo@126.com.
authors.forename: Xiuyan
authors.initials: X
authors.lastname: Guo
mesh_terms: D000328:Adult; D001931:Brain Mapping / Q000379:methods*; D002540:Cerebral Cortex / Q000502:physiology*; D004645:Empathy / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010146:Pain / Q000523:psychology*; D012938:Social Perception; D055815:Young Adult
keywords: Anterior insular cortex; Empathy for pain; Reputation; dACC; fMRI