title: Carotid stent-assisted thrombectomy in acute ischemic stroke.
abstract: Acute carotid occlusion or near-occlusion with concomitant intracranial embolism cause severe acute ischemic strokes in patients. These concomitant occlusions have suggested poor response to intravenous thrombolysis and complicate endovascular treatment. Nevertheless, endovascular stent-assisted thrombectomy may improve outcome in patients but the treatment is not without concerns. Required antiplatelet therapy to prevent stent thrombosis may increase the rate of intracranial hemorrhage, especially after recent thrombolysis. Furthermore, technical difficulties in access of the intracranial vasculature may cause adverse events, even in the hands of experienced interventionalists. These concerns currently defy the treatment in being recommended for general use and only on a compassionate basis. However, recent patient series have suggested reasonable safety and efficacy for carotid stent-assisted thrombectomy.
authors.affiliation: Department of Neurology, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark.
authors.forename: Henrik
authors.initials: H
authors.lastname: Steglich-Arnholm
authors.affiliation: Department of Neurology, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark.|Faculty of Health & Medical Science, University of Copenhagen, Blegdamsvej 3B, København N 2200, Denmark.
authors.forename: Derk W
authors.initials: DW
authors.lastname: Krieger
mesh_terms: D000208:Acute Disease; D002545:Brain Ischemia / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D002339:Carotid Arteries / Q000601:surgery*; D016893:Carotid Stenosis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D003952:Diagnostic Imaging; D057510:Endovascular Procedures / Q000379:methods*; D006801:Humans; D015607:Stents; D017131:Thrombectomy / Q000379:methods*; D016896:Treatment Outcome
keywords: antiplatelet hemorrhage; atherosclerosis; carotid stent-assisted thrombectomy; stroke dissection