title: Evaluation of Interventional Therapy for Patients with Intracranial Vertebral Artery Stenosis by Transcranial Color-Coded Sonography.
abstract: The aim of this study was to evaluate the efficacy of stenting for patients with intra-cranial vertebral artery stenosis by trans-cranial color-coded sonography and to analyze the risk factors of in-stent restenosis (ISR). In total, 121 patients with intra-cranial vertebral artery stenosis stents were included. The follow-up time was 3-12 mo (mean: 9.9 mo). The success rate was 92.6%. Peak systolic velocity and end-diastolic velocity decreased from 261 ± 63 to 109 ± 41 cm/s and from 133 ± 44 to 47 ± 18 cm/s, respectively (both p < 0.001). Peak systolic velocity (245 ± 47 cm/s) and end-diastolic velocity (121 ± 31 cm/s) of patients with ISR (18.9%, 20/106) were higher than those of patients without ISR (101 ± 38 and 44 ± 17 cm/s, respectively) at 12 mo post-procedure (p < 0.05). The length of the stent and residual stenosis were related to ISR. In conclusion, stenting is a feasible treatment method for intra-cranial vertebral artery stenosis. Trans-cranial color-coded sonography can be used for monitoring patients to identify ISR.
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Yinghua
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China. Electronic address: dryanghua99@163.com.
authors.forename: Yang
authors.initials: Y
authors.lastname: Hua
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Lingyun
authors.initials: L
authors.lastname: Jia
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Beibei
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Duan
authors.affiliation: Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Liqun
authors.initials: L
authors.lastname: Jiao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color; D017585:Ultrasonography, Doppler, Transcranial; D018084:Ultrasonography, Interventional; D014711:Vertebral Artery / Q000000981:diagnostic imaging / Q000601:surgery; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging* / Q000601:surgery*
keywords: In-stent restenosis; Intra-cranial vertebral artery; Stenosis; Stenting; Trans-cranial color-coded sonography