title: Electronic communication of cells with a surface mediated by boronic acid saccharide interactions.
abstract: The fabrication of a molecularly tailored surface functionalised with a saccharide binding motif, a phenyl boronic acid derivative is reported. The functionalised surface facilitated the transfer of electrons, via unique electronic interactions mediated by the presence of the boronic acid, from a macrophage cell line. This is the first example of eukaryotic cellular-electrical communication mediated by the binding of cells via their cell-surface saccharide units.
authors.affiliation: School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK.
authors.forename: Alex
authors.initials: A
authors.lastname: Stephenson-Brown
authors.affiliation: School of Pharmacy, University of Nottingham, University Park Nottingham, Nottingham, Nottinghamshire, NG7 2RD, UK.
authors.forename: Sue
authors.initials: S
authors.lastname: Yong
authors.affiliation: School of Pharmacy, University of Nottingham, University Park Nottingham, Nottingham, Nottinghamshire, NG7 2RD, UK.
authors.forename: Muhammad H
authors.initials: MH
authors.lastname: Mansor
authors.affiliation: School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK.
authors.forename: Zarrar
authors.initials: Z
authors.lastname: Hussein
authors.affiliation: School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK.
authors.forename: Nga-Chi
authors.initials: NC
authors.lastname: Yip
authors.affiliation: School of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK.
authors.forename: Paula M
authors.initials: PM
authors.lastname: Mendes
authors.affiliation: School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, UK.
authors.forename: John S
authors.initials: JS
authors.lastname: Fossey
authors.affiliation: Laboratory of Biophysics and Surface Analysis, School of Pharmacy, University of Nottingham, University Park Nottingham, Nottingham, Nottinghamshire, NG7 2RD, UK. frankie.rawson@nottingham.ac.uk.
authors.forename: Frankie J
authors.initials: FJ
authors.lastname: Rawson
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D004583:Electrons; D013499:Surface Properties
chemical_list: D001897:Boronic Acids; D002241:Carbohydrates