title: Investigation of orbitofrontal sulcogyral pattern in chronic schizophrenia.
abstract: Abnormalities of orbitofrontal cortex (OFC) pattern type distribution have been associated with schizophrenia-spectrum disorders. We investigated OFC pattern type in a large sample of chronic schizophrenia patients and healthy controls. We found an increased frequency of Type II but no difference in Type I or III folding pattern in the schizophrenia group in comparison to controls. Further large studies are required to investigate the diagnostic specificity of altered OFC pattern type and to confirm the distribution of pattern type in the normal population.
authors.affiliation: Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton South, Victoria 3053, Australia. Electronic address: vcropley@unimelb.edu.au.
authors.forename: Vanessa L
authors.initials: VL
authors.lastname: Cropley
authors.affiliation: Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton South, Victoria 3053, Australia; Orygen, The National Centre of Excellence in Youth Mental Health, The University of Melbourne and Melbourne Health, Parkville, Victoria 3052, Australia.
authors.forename: Cali F
authors.initials: CF
authors.lastname: Bartholomeusz
authors.affiliation: Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton South, Victoria 3053, Australia.
authors.forename: Peter
authors.initials: P
authors.lastname: Wu
authors.affiliation: Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton South, Victoria 3053, Australia; School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Wood
authors.affiliation: Orygen, The National Centre of Excellence in Youth Mental Health, The University of Melbourne and Melbourne Health, Parkville, Victoria 3052, Australia.
authors.forename: Tina
authors.initials: T
authors.lastname: Proffitt
authors.affiliation: Orygen, The National Centre of Excellence in Youth Mental Health, The University of Melbourne and Melbourne Health, Parkville, Victoria 3052, Australia; Department of Psychiatry, The University of Melbourne, Parkville, Victoria 3052, Australia.
authors.forename: Warrick J
authors.initials: WJ
authors.lastname: Brewer
authors.affiliation: Department of Medicine and Radiology, The University of Melbourne, Royal Melbourne Hospital, Carlton South, Victoria 3053, Australia.
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Desmond
authors.affiliation: Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton South, Victoria 3053, Australia.
authors.forename: Dennis
authors.initials: D
authors.lastname: Velakoulis
authors.affiliation: Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Carlton South, Victoria 3053, Australia; Florey Institute of Neuroscience and Mental Health, Parkville, Victoria 3052, Australia; Department of Psychiatry, The University of Melbourne, Parkville, Victoria 3052, Australia.
authors.forename: Christos
authors.initials: C
authors.lastname: Pantelis
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D017397:Prefrontal Cortex / Q000473:pathology*; D012559:Schizophrenia / Q000175:diagnosis*
keywords: Orbitofrontal cortex; Pattern type; Schizophrenia