title: Catalytic Borylation using an Air-Stable Zinc Boryl Reagent: Systematic Access to Elusive Acylboranes.
abstract: The use of borylzinc reagents in palladium-catalyzed borylation chemistry is described (i.e. a boron analogue of the Negishi coupling), including a one-pot bench-top protocol using an air- and moisture-stable bis(boryl)zinc reagent. The steric/electronic properties of the boryl fragment employed enable a systematic method for accessing acylboranes, a rare class of organoboron species with great potential in chemical synthesis. The reactions proceed under mild conditions, use inexpensive commercial sources of palladium, and demonstrate a remarkable functional-group tolerance.
authors.affiliation: Inorganic Chemistry Laboratory, Dept. of Chemistry, University of Oxford, South Parks Rd, Oxford (UK) OX1 3QR. jesus.camposmanzano@chem.ox.ac.uk.
authors.forename: Jesús
authors.initials: J
authors.lastname: Campos
authors.affiliation: Inorganic Chemistry Laboratory, Dept. of Chemistry, University of Oxford, South Parks Rd, Oxford (UK) OX1 3QR. simon.aldridge@chem.ox.ac.uk.
authors.forename: Simon
authors.initials: S
authors.lastname: Aldridge
keywords: boron; borylation; palladium; structure elucidation; zinc