title: Extensive Recruitment of Plasma Blasts to the Cerebrospinal Fluid in Toscana Virus Encephalitis.
abstract: An unexpectedly extensive recruitment of B cells and plasma blasts to the cerebrospinal fluid (CSF) in a patient with Toscana virus (TOSV) encephalitis is described. Acute infection by TOSV was demonstrated by serological methods and by detection of TOSV-specific nucleic acid in the CSF by real-time polymerase chain reaction and sequencing.
authors.affiliation: Department of Neurology , Klinikum Rechts der Isar, Technische Universität München.
authors.forename: Lucas
authors.initials: L
authors.lastname: Schirmer
authors.affiliation: Departments of Virology and Rickettsiology.
authors.forename: Silke
authors.initials: S
authors.lastname: Wölfel
authors.affiliation: Microbial Genomics and Bioinformatics , Bundeswehr Institute of Microbiology, German Center for Infection Research (DZIF).
authors.forename: Enrico
authors.initials: E
authors.lastname: Georgi
authors.affiliation: Department of Neurology , Klinikum Rechts der Isar, Technische Universität München.
authors.forename: Markus
authors.initials: M
authors.lastname: Ploner
authors.affiliation: Institute of Virology, Technische Universität München and Helmholtz Zentrum München, German Center for Infection Research (DZIF).
authors.forename: Barbara
authors.initials: B
authors.lastname: Bauer
authors.affiliation: Department of Neurology , Klinikum Rechts der Isar, Technische Universität München ; Munich Cluster for Systems Neurology (SyNergy) , Munich , Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Hemmer
keywords: B cells; Toscana virus; cerebrospinal fluid; encephalitis; plasma blasts