title: A novel T wave cancellation method based on MAP estimation for P wave extraction.
abstract: P wave and T wave in human-body electrocardiogram (ECG) signals often fuse together when atrial premature contract (APC) occurs. P waves within the fused signals are valuable for the measurement of P wave parameters as well as diagnosis of supra-ventricular arrhythmias. However, the problem of extracting P wave from the fused signals is seldom addressed. In this study, a novel T wave cancellation method for P wave extraction based on maximum a posteriori (MAP) estimation is proposed. In order to accurately cancel the T wave within the fused signal, T wave and the timing point of T wave peak are estimated simultaneously. The estimated timing point of T wave peak is used as alignment reference point for T wave subtraction. Simulation results show that the proposed method outperform the traditional T wave cancellation method in terms of both normalized mean square error and cross-correlation index. The results for real ECGs with APC demonstrate that the extracted P waves using the proposed method are more similar to the non-overlapping P waves in terms of morphology than the ones using the traditional T wave cancellation method.
authors.affiliation: Automatic Test And Control Institute, Harbin Institute of Technology, Harbin, China.
authors.forename: Chang-An
authors.initials: CA
authors.lastname: Wei
authors.affiliation: Shenzhen Institutes of Advanced Academy of Sciences, Chinese Academy of Sciences, China.
authors.forename: Huhe
authors.initials: H
authors.lastname: Dai
mesh_terms: D000465:Algorithms; D018880:Atrial Premature Complexes / Q000175:diagnosis*; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004562:Electrocardiography / Q000379:methods*; D006801:Humans; D000069550:Machine Learning; D015233:Models, Statistical; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: Electrocardiogram; P wave extraction; atrial premature contract; maximum a posteriori