title: Achromobacter Xylosoxidans Bloodstream Infection in Elderly Patient with Hepatocellular Carcinoma: Case Report and Review of Literature.
abstract: Achromobacter xylosoxidansis a nonfermentative Gram-negative organism, known to cause opportunistic infection in humans. We report a case of septicemia in a 76-year-old male patient with underlying hepatocellular carcinoma due to A. xylosoxidans, which showed a different antimicrobial susceptibility pattern from what is usually reported. From aerobic blood culture of the patient, A. xylosoxidans was isolated which was found to be sensitive to amoxicillin-clavulanic acid, piperacillin-tazobactam, ceftazidime, cefoperazone-sulbactam, meropenem, minocycline, tigecycline, and trimethoprim/sulfamethoxazole. The patient recovered with amoxicillin-clavulanic acid treatment, which was given empirically to the patient. The present case highlights the possible role of amoxicillin-clavulanic acid for treatment of bloodstream infection with A. xylosoxidans.
authors.affiliation: Department of Laboratory Medicine, Delhi State Cancer Institute, New Delhi, India.
authors.forename: Kausalya
authors.initials: K
authors.lastname: Raghuraman
authors.affiliation: Department of Laboratory Medicine, Delhi State Cancer Institute, New Delhi, India.
authors.forename: Nishat H
authors.initials: NH
authors.lastname: Ahmed
authors.affiliation: Department of Laboratory Medicine, Delhi State Cancer Institute, New Delhi, India.
authors.forename: Frincy K
authors.initials: FK
authors.lastname: Baruah
authors.affiliation: Department of Clinical Oncology, Delhi State Cancer Institute, New Delhi, India.
authors.forename: Rajesh K
authors.initials: RK
authors.lastname: Grover
keywords: Achromobacter xylosoxidans; amoxicillin-clavulanic acid; blood stream infection