title: Microfluidic multiplexed partitioning enables flexible and effective utilization of magnetic sensor arrays.
abstract: We demonstrate microfluidic partitioning of a giant magnetoresistive sensor array into individually addressable compartments that enhances its effective use. Using different samples and reagents in each compartment enables measuring of cross-reactive species and wide dynamic ranges on a single chip. This compartmentalization technique motivates the employment of high density sensor arrays for highly parallelized measurements in lab-on-a-chip devices.
authors.affiliation: Mechanical Engineering, Stanford University, Stanford, CA 94305, USA.
authors.forename: Daniel J B
authors.initials: DJ
authors.lastname: Bechstein
authors.affiliation: Bioengineering, Stanford University, Stanford, CA 94305, USA.
authors.forename: Elaine
authors.initials: E
authors.lastname: Ng
authors.affiliation: Mechanical Engineering, Stanford University, Stanford, CA 94305, USA.
authors.forename: Jung-Rok
authors.initials: JR
authors.lastname: Lee
authors.affiliation: Biomedical Engineering, University of North Carolina, Chapel Hill, NC 27514, USA.
authors.forename: Stephanie G
authors.initials: SG
authors.lastname: Cone
authors.affiliation: Bioengineering, Stanford University, Stanford, CA 94305, USA and Medicine, Harvard University, Cambridge, MA 02138, USA.
authors.forename: Richard S
authors.initials: RS
authors.lastname: Gaster
authors.affiliation: MagArray Inc., Milpitas, CA 95035, USA.
authors.forename: Sebastian J
authors.initials: SJ
authors.lastname: Osterfeld
authors.affiliation: Electrical Engineering, Stanford University, Stanford, CA 94305, USA. sxwang@stanford.edu and Electrical and Computer Engineering, UCSD, La Jolla, CA 92093, USA.
authors.forename: Drew A
authors.initials: DA
authors.lastname: Hall
authors.affiliation: Electrical Engineering, Stanford University, Stanford, CA 94305, USA. sxwang@stanford.edu.
authors.forename: James A
authors.initials: JA
authors.lastname: Weaver
authors.affiliation: Material Science, Stanford University, Stanford, CA 94305, USA.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Wilson
authors.affiliation: Electrical Engineering, Stanford University, Stanford, CA 94305, USA. sxwang@stanford.edu and Material Science, Stanford University, Stanford, CA 94305, USA.
authors.forename: Shan X
authors.initials: SX
authors.lastname: Wang
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation; D007118:Immunoassay / Q000295:instrumentation; D056656:Lab-On-A-Chip Devices; D060526:Magnetic Fields; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*; D011506:Proteins / Q000032:analysis
chemical_list: D011506:Proteins