title: A facile synthesis of superparamagnetic Fe3O4 supraparticles@MIL-100(Fe) core-shell nanostructures: Preparation, characterization and biocompatibility.
abstract: Superparamagnetic Fe3O4 supraparticles@MIL-100(Fe) core-shell nanostructure microspheres were successfully constructed by a facile step-by-step method. The polyacrylate formed in situ during the process of the preparation of Fe3O4 supraparticles not only acted as a stabilizer on the Fe3O4 nanoparticles surface, but also played a crucial role as a "bridge" in the initial stage of the framework components selectively assembly on the Fe3O4 supraparticle surfaces. The structure and composition of the obtained microspheres were characterized by SEM, TEM, DLS, XRD, FTIR, and TG analysis. The MPMS results revealed that the introduction of the MOF shells can inhibit the interplay among the neighboring Fe3O4 supraparticles while an external magnetic field applied. The well-dispersed microspheres are biocompatible, which endow the microspheres great potential in drug targeting applications with enhanced efficiency.
authors.affiliation: Laboratory of Functional and Biomedical Nanomaterials, College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
authors.forename: Shoushan
authors.initials: S
authors.lastname: Yu
authors.affiliation: Laboratory of Functional and Biomedical Nanomaterials, College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China.
authors.forename: Jiaqi
authors.initials: J
authors.lastname: Wan
authors.affiliation: Laboratory of Functional and Biomedical Nanomaterials, College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China. Electronic address: kchen@qust.edu.cn.
authors.forename: Kezheng
authors.initials: K
authors.lastname: Chen
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D058185:Magnetite Nanoparticles; D007501:Iron
keywords: Core–shell nanostructures; Fe(3)O(4) supraparticles; MIL-100(Fe); Step-by-step method