title: Effects of Ultrasonic Disintegrates from Epimastigote Biomass of Trypanosoma cruzi Albarrada Strain (Mexico) on the Development of L5178Y Solid Malignant Transplanted Tumors in Male BALB/c Mice.
abstract: We studied in vivo antitumor effect of epimastigote form detritus of Trypanosoma cruzi, Mexican Albarrada strain, on L5178Y malignant tumor in BALB/c mice. The antitumor effect of ultrasonic detritus of the parasite was confirmed by shrinkage of the tumor and changed size of its symplastic necroses.
authors.affiliation: Department of Microbiology and Virology, Medical Faculty, Russian University of Peoples' Friendship, Moscow, Russia.
authors.forename: R R
authors.initials: RR
authors.lastname: Sadretdinova
authors.affiliation: Department of Microbiology and Virology, Medical Faculty, Russian University of Peoples' Friendship, Moscow, Russia.
authors.forename: L P
authors.initials: LP
authors.lastname: Karpenko
authors.affiliation: Department of Microbiology and Virology, Medical Faculty, Russian University of Peoples' Friendship, Moscow, Russia.
authors.forename: M V
authors.initials: MV
authors.lastname: Dalin
authors.affiliation: Laboratory of Molecular Biology, School of Medicine, University of Colima, Colima, Mexico.
authors.forename: V
authors.initials: V
authors.lastname: Mel'nikov
authors.affiliation: Laboratory of Molecular Biology, School of Medicine, University of Colima, Colima, Mexico. carreonf@hotmail.com.
authors.forename: V
authors.initials: V
authors.lastname: Carreón-Fernández
authors.affiliation: Laboratory of Molecular Biology, School of Medicine, University of Colima, Colima, Mexico.
authors.forename: O
authors.initials: O
authors.lastname: Newton-Sánchez
authors.affiliation: Laboratory of Molecular Biology, School of Medicine, University of Colima, Colima, Mexico.
authors.forename: F
authors.initials: F
authors.lastname: Rojas-Larios
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D008223:Lymphoma / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D013010:Sonication; D014349:Trypanosoma cruzi / Q000737:chemistry*; D047368:Tumor Burden / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents
keywords: L5178Y; Trypanosoma cruzi; antitumor effect; cancer