title: Predicting Later Study Withdrawal in Participants Active in a Longitudinal Birth Cohort Study for 1 Year: The TEDDY Study.
abstract: OBJECTIVE
  To identify predictors of later study withdrawal among participants active in The Environmental Determinants of Diabetes in the Young (TEDDY) for 1 year.
  
  
  METHODS
  Multiple logistic regression was used to discriminate 3,042 children active in TEDDY for the first 3 years from 432 children who withdrew in Years 2 or 3. Predictor variables were tested in blocks-demographic, maternal lifestyle behaviors, stress and child illness, maternal reactions to child's increased diabetes risk, in-study behaviors-and a final best model developed.
  
  
  RESULTS
  Few demographic factors predicted study withdrawal. Maternal lifestyle behaviors, accuracy of the mother's risk perception, and in-study behaviors were more important. Frequent child illnesses were associated with greater study retention.
  
  
  CONCLUSIONS
  Demographic measures are insufficient predictors of later study withdrawal among those active in a study for at least 1 year; behavioral/psychological factors offer improved prediction and guidance for the development of retention strategies.
authors.affiliation: Department of Behavioral Science and Social Medicine, Florida State University, suzanne.johnson@med.fsu.edu.
authors.forename: Suzanne Bennett
authors.initials: SB
authors.lastname: Johnson
authors.affiliation: Health Informatics Institute, University of South Florida.
authors.forename: Kristian F
authors.initials: KF
authors.lastname: Lynch
authors.affiliation: Barbara Davis Center for Childhood Diabetes, University of Colorado.
authors.forename: Judith
authors.initials: J
authors.lastname: Baxter
authors.affiliation: Department of Clinical Sciences, Lund University.
authors.forename: Barbro
authors.initials: B
authors.lastname: Lernmark
authors.affiliation: Helmholtz Center and Institute for Psychology, Graz University.
authors.forename: Roswith
authors.initials: R
authors.lastname: Roth
authors.affiliation: Department of Pediatrics, University of Turku, and.
authors.forename: Tuula
authors.initials: T
authors.lastname: Simell
authors.affiliation: Health Informatics Institute, University of South Florida.
authors.forename: Laura
authors.initials: L
authors.lastname: Smith
mesh_terms: D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology* / Q000235:genetics; D016021:Epidemiologic Studies; D005260:Female; D006801:Humans; D007223:Infant; D008019:Life Style; D008137:Longitudinal Studies; D008297:Male; D009035:Mothers / Q000706:statistics & numerical data*; D015337:Multicenter Studies as Topic; D010352:Patient Dropouts / Q000706:statistics & numerical data*; D012307:Risk Factors
keywords: adherence; diabetes; genetics and genetic disorders; longitudinal research; prevention/control; research design and methods