title: Bacterial contamination of propofol vials used in operating rooms of a third-level hospital.
abstract: We found a 6.1% bacterial contamination rate among 198 propofol vials collected after clinical use in 12 operating rooms of a high-complexity hospital in Cali, Colombia. Some propofol vials were used for extended periods (up to 72 hours), and only 26.1% of vials were punctured once. Median time of use, although not statistically significant, was higher in positive samples (7.2 vs 3.5 hours, P = .08). Education on the topic should stress that vials are single-patient use and must be immediately discarded after use.
authors.affiliation: School of Medicine, Faculty of Health, Universidad del Valle, Cali, Colombia. Electronic address: andres.zorrilla@correounivalle.edu.co.
authors.forename: Andrés
authors.initials: A
authors.lastname: Zorrilla-Vaca
authors.affiliation: School of Medicine, Faculty of Health, Universidad del Valle, Cali, Colombia.
authors.forename: Kevin
authors.initials: K
authors.lastname: Escandón-Vargas
authors.affiliation: School of Medicine, Faculty of Health, Universidad del Valle, Cali, Colombia.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Brand-Giraldo
authors.affiliation: Department of Anesthesiology, Hospital Universitario del Valle, Universidad del Valle, Cali, Colombia.
authors.forename: Tatiana
authors.initials: T
authors.lastname: León
authors.affiliation: Department of Anesthesiology, Hospital Universitario del Valle, Universidad del Valle, Cali, Colombia.
authors.forename: Mónica
authors.initials: M
authors.lastname: Herrera
authors.affiliation: School of Bacteriology and Clinic Laboratory, Faculty of Health, Universidad del Valle, Cali, Colombia.
authors.forename: Andrey
authors.initials: A
authors.lastname: Payán
mesh_terms: D018686:Anesthetics, Intravenous / Q000627:therapeutic use*; D001419:Bacteria / Q000254:growth & development*; D003105:Colombia; D004340:Drug Contamination / Q000706:statistics & numerical data*; D006761:Hospitals / Q000592:standards; D006801:Humans; D009873:Operating Rooms / Q000592:standards; D015742:Propofol / Q000627:therapeutic use*; D013594:Syringes
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol
keywords: Anesthetics; Bacterial growth; Drug contamination; Operating rooms; Propofol