title: Breast cancer following spinal irradiation for a childhood cancer: A report from the Childhood Cancer Survivor Study.
abstract: It has been suggested that pediatric patients treated with spinal irradiation may have an elevated risk of breast cancer. Among a cohort of 363 long-term survivors of a pediatric central nervous system tumor or leukemia treated with spinal irradiation, there was little evidence of an increased breast cancer risk.
authors.affiliation: Memorial Sloan Kettering Cancer Center, New York, United States. Electronic address: moskowc1@mskcc.org.
authors.forename: Chaya S
authors.initials: CS
authors.lastname: Moskowitz
authors.affiliation: Rutgers Cancer Institute of New Jersey, New Brunswick, United States.
authors.forename: Jyoti
authors.initials: J
authors.lastname: Malhotra
authors.affiliation: Memorial Sloan Kettering Cancer Center, New York, United States.
authors.forename: Joanne F
authors.initials: JF
authors.lastname: Chou
authors.affiliation: Memorial Sloan Kettering Cancer Center, New York, United States.
authors.forename: Suzanne L
authors.initials: SL
authors.lastname: Wolden
authors.affiliation: University of Texas MD Anderson Cancer Center, Houston, United States.
authors.forename: Rita E
authors.initials: RE
authors.lastname: Weathers
authors.affiliation: University of Texas MD Anderson Cancer Center, Houston, United States.
authors.forename: Marilyn
authors.initials: M
authors.lastname: Stovall
authors.affiliation: St. Jude Children's Research Hospital, Memphis, United States.
authors.forename: Gregory T
authors.initials: GT
authors.lastname: Armstrong
authors.affiliation: Fred Hutchinson Cancer Research Center, Seattle, United States.
authors.forename: Wendy M
authors.initials: WM
authors.lastname: Leisenring
authors.affiliation: University of Minnesota Masonic Cancer Center, Minneapolis, United States.
authors.forename: Joseph P
authors.initials: JP
authors.lastname: Neglia
authors.affiliation: St. Jude Children's Research Hospital, Memphis, United States.
authors.forename: Leslie L
authors.initials: LL
authors.lastname: Robison
authors.affiliation: Memorial Sloan Kettering Cancer Center, New York, United States.
authors.forename: Kevin C
authors.initials: KC
authors.lastname: Oeffinger
mesh_terms: D000293:Adolescent; D001943:Breast Neoplasms / Q000453:epidemiology / Q000209:etiology*; D016543:Central Nervous System Neoplasms / Q000453:epidemiology / Q000532:radiotherapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007938:Leukemia / Q000453:epidemiology / Q000532:radiotherapy*; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000209:etiology*; D016609:Neoplasms, Second Primary / Q000453:epidemiology / Q000209:etiology*; D011879:Radiotherapy Dosage; D012306:Risk; D017741:Survivors; D014481:United States / Q000453:epidemiology
keywords: Craniospinal irradiation; Late effects; Secondary breast cancer