title: Renin-associated hypertension after bronchial artery embolization in cystic fibrosis.
abstract: Bronchial artery embolization is the recommended therapy for massive hemoptysis in patients with cystic fibrosis (CF). We report on two cases of multiple renal infarcts and renin-associated hypertension and hypokalemia occurring in CF adults after bronchial artery embolizations. These complications were presumably related to crossing of small calibrated microspheres through arteriovenous anastomoses. Although hypokalemia resolved rapidly, hypertension persisted at least 6 months and its control required multiple antihypertensive agents. Physicians should be aware of this potentially severe, but previously unreported, complication of bronchial artery embolization.
authors.affiliation: Service de Pneumologie, Hôpital Cochin, AP-HP, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Coolen
authors.affiliation: Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Service de Radiologie A, Hôpital Cochin, AP-HP, Paris, France.
authors.forename: Hervé
authors.initials: H
authors.lastname: Gouya
authors.affiliation: Service de Pneumologie, Hôpital Cochin, AP-HP, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
authors.forename: Reem
authors.initials: R
authors.lastname: Kanaan
authors.affiliation: Service de Pneumologie, Hôpital Cochin, AP-HP, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Honoré
authors.affiliation: Service de Pneumologie, Hôpital Cochin, AP-HP, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
authors.forename: Jeanne
authors.initials: J
authors.lastname: Chapron
authors.affiliation: Service de Pneumologie, Hôpital Cochin, AP-HP, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Hubert
authors.affiliation: Université Paris Descartes, Sorbonne Paris Cité, Paris, France; Service de Radiologie A, Hôpital Cochin, AP-HP, Paris, France.
authors.forename: Paul
authors.initials: P
authors.lastname: Legmann
authors.affiliation: Service de Pneumologie, Hôpital Cochin, AP-HP, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
authors.forename: Daniel
authors.initials: D
authors.lastname: Dusser
authors.affiliation: Service de Pneumologie, Hôpital Cochin, AP-HP, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Electronic address: pierre-regis.burgel@aphp.fr.
authors.forename: Pierre-Régis
authors.initials: PR
authors.lastname: Burgel
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D001981:Bronchial Arteries; D001999:Bronchoscopy; D003550:Cystic Fibrosis / Q000097:blood / Q000150:complications*; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D005260:Female; D006469:Hemoptysis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D012083:Renin / Q000097:blood*; D014057:Tomography, X-Ray Computed
chemical_list: D012083:Renin
keywords: Bronchial artery embolization; Hemoptysis; Hyperaldosteronism; Hypertension; Renal infarction