title: [Solid-phase extraction based on mesoporous Fe3O4 @ mSiO2 @ Cu2+ magnetic nanoparticles coupled with high performance liquid chromatography for the determination of microcystins in water samples].
abstract: Mesoporous magnetic nanoparticles of Fe3O4 @ mSiO2 @ Cu2+ were synthesized by two methods of hydrothermal synthesis and room temperature synthesis. The synthesized mesoporous Fe3O4 @ mSiO2 @ Cu2+ nanoparticles presented uniform sizes, good magnetic properties and specific selectivity. In this work, a novel magnetic solid-phase extraction (MSPE) method based on mesoporous Fe3O4 @ mSiO2 @ Cu2+ nanoparticles (NPs) coupled with high performance liquid chromatography (HPLC) was developed for the simultaneous extraction of trace amount of microcystin-LR (MC-LR) in water samples. The MSPE extraction conditions and HPLC conditions were optimized. The results showed that good linear relationship (r = 0.999 4) was obtained between peak area and mass concentration of MC-LR in the range of 0.1-15 µg/L. The limit of detection was 0.025 µg/L, and the limit of quantification was 0.082 µg/L. Furthermore, this method was used for the analysis of algal toxins in water samples with the recovery of 78%. The results indicated that Fe3O4 @ mSiO2 @ Cu2+ magnetic nanoparticles were good pretreatment alternatives for the concentration of microcystin-LR in water samples.
authors.forename: Hong
authors.initials: H
authors.lastname: Sun
authors.forename: Dawei
authors.initials: D
authors.lastname: Lou
authors.forename: Lili
authors.initials: L
authors.lastname: Lian
authors.forename: Xue
authors.initials: X
authors.lastname: Han
authors.forename: Tingxiu
authors.initials: T
authors.lastname: Guo
authors.forename: Tujun
authors.initials: T
authors.lastname: Chen
mesh_terms: D002851:Chromatography, High Pressure Liquid; D003300:Copper / Q000737:chemistry; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008387:Marine Toxins; D052998:Microcystins / Q000032:analysis*; D012822:Silicon Dioxide / Q000737:chemistry; D052616:Solid Phase Extraction; D014867:Water / Q000032:analysis*
chemical_list: D058185:Magnetite Nanoparticles; D008387:Marine Toxins; D052998:Microcystins; D014867:Water; D012822:Silicon Dioxide; D003300:Copper; C057862:cyanoginosin LR