title: Intervention Thresholds and the Diagnosis of Osteoporosis.
abstract: A position paper of the National Bone Health Alliance recently recommended that diagnostic criteria for osteoporosis be redefined. We review the merits and demerits of this proposal and argue that the operational bone mineral density (BMD)-based definition be retained while clarity is brought to bear on the distinction between diagnostic and intervention thresholds.
authors.affiliation: Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, United Kingdom.
authors.forename: John A
authors.initials: JA
authors.lastname: Kanis
authors.affiliation: Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, United Kingdom.
authors.forename: Eugene V
authors.initials: EV
authors.lastname: McCloskey
authors.affiliation: MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom.
authors.forename: Nicholas C
authors.initials: NC
authors.lastname: Harvey
authors.affiliation: Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, United Kingdom.
authors.forename: Helena
authors.initials: H
authors.lastname: Johansson
authors.affiliation: University of Manitoba, Winnipeg, Canada.
authors.forename: William D
authors.initials: WD
authors.lastname: Leslie
mesh_terms: D015519:Bone Density; D006801:Humans; D010024:Osteoporosis / Q000175:diagnosis* / Q000378:metabolism
keywords: DEFINITION; DIAGNOSIS; FRACTURE RISK; FRAX; INTERVENTION THRESHOLDS; OSTEOPOROSIS