title: A Pivotal Role of DELLAs in Regulating Multiple Hormone Signals.
abstract: Plant phenotypic plasticity is controlled by diverse hormone pathways, which integrate and convey information from multiple developmental and environmental signals. Moreover, in plants many processes such as growth, development, and defense are regulated in similar ways by multiple hormones. Among them, gibberellins (GAs) are phytohormones with pleiotropic actions, regulating various growth processes throughout the plant life cycle. Previous work has revealed extensive interplay between GAs and other hormones, but the molecular mechanism became apparent only recently. Molecular and physiological studies have demonstrated that DELLA proteins, considered as master negative regulators of GA signaling, integrate multiple hormone signaling pathways through physical interactions with transcription factors or regulatory proteins from different families. In this review, we summarize the latest progress in GA signaling and its direct crosstalk with the main phytohormone signaling, emphasizing the multifaceted role of DELLA proteins with key components of major hormone signaling pathways.
authors.affiliation: Institut de Biologie Moléculaire des Plantes (IBMP), UPR2357, associé avec l'Université de Strasbourg, 12, rue Général Zimmer, 67084 Strasbourg Cedex, France. Electronic address: jean-michel.daviere@ibmp-cnrs.unistra.fr.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Davière
authors.affiliation: Institut de Biologie Moléculaire des Plantes (IBMP), UPR2357, associé avec l'Université de Strasbourg, 12, rue Général Zimmer, 67084 Strasbourg Cedex, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Achard
mesh_terms: D029681:Arabidopsis Proteins / Q000378:metabolism; D005875:Gibberellins / Q000378:metabolism*; D063245:Plant Development; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*; D012639:Seeds / Q000254:growth & development / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D029681:Arabidopsis Proteins; C109555:GAI protein, Arabidopsis; D005875:Gibberellins; D010940:Plant Proteins
keywords: DELLAs; gibberellins; hormone crosstalk; phenotypic plasticity; plant development