title: [L-Lysine-α-Oxidase in vitro Activity in Experiments on Models of Viruses Sindbis, Forest-Spring Encephalitis, Western Nile, Tyaginya and Dhori].
abstract: The antitumor effect of L-lysine-α-oxidase from the culture fluid of Trichoderma harzianum Rifai F-180 was investigated for the first time. The in vitro studies revealed its high activity on a model of the forest-spring encephalitis virus and no activity against the Sindbis, Western Nile, Tyaginya and Dhori viruses.
authors.forename: I P
authors.initials: IP
authors.lastname: Smirnova
authors.forename: V F
authors.initials: VF
authors.lastname: Larichev
authors.forename: Yu A
authors.initials: YA
authors.lastname: Shneider
mesh_terms: D000594:Amino Acid Oxidoreductases / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002522:Chlorocebus aethiops; D058492:Drug Repositioning; D004669:Encephalitis Viruses, Tick-Borne / Q000187:drug effects* / Q000254:growth & development; D005656:Fungal Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D016851:Orthobunyavirus / Q000254:growth & development; D012845:Sindbis Virus / Q000254:growth & development; D013552:Swine; D018117:Thogotovirus / Q000254:growth & development; D014242:Trichoderma / Q000737:chemistry* / Q000201:enzymology; D014709:Vero Cells; D014902:West Nile virus / Q000254:growth & development
chemical_list: D000970:Antineoplastic Agents; D000998:Antiviral Agents; D005656:Fungal Proteins; D000594:Amino Acid Oxidoreductases; C041123:L-lysine oxidase