title: Incidence Trends and Geographical Distribution of Nasopharyngeal Carcinoma in Iran.
abstract: BACKGROUND
  Nasopharyngeal carcinoma (NPC) has known as a highly distinct kind of head and neck cancer. This distinction has been due to its clinical presentation, epidemiology, outcome, and treatment. There have not been any reports of epidemiological analysis of NPC in Iran. This study has evaluated the incidence rates and trends of nasopharyngeal carcinoma in the Iranian population during 2004 to 2009.
  
  
  METHODS
  The data have collected from the Iranian national cancer data system registry. All the cases of nasopharyngeal carcinoma (with the topography code 11 and histology of carcinoma) have retrieved and analyzed from an overall cancer database during a 6-year period. The data have analyzed by using the SPSS, version 16.
  
  
  RESULTS
  To determine the current incidence of NPC in Iran, we have examined the NPC cases from 2004 to 2009. A total of 1431 cases (981 male and 450 female NPC patients) have analyzed epidemiologically in this study. The mean age of the patients was 47.1 years. The incidence was 0.33 per 100000 persons. The overall incidence rate have increased annually (p<0.05). The incidence of NPC gradually increased with age. Prefectures that bordering the Caspian Sea have proved to have a higher incidence than the other studied areas.
  
  
  CONCLUSIONS
  Our study has indicated an increasing trend in the incidence of nasopharyngeal carcinoma. Therefore; attempts should be precipitated for prevention.
authors.affiliation: Dept. of Otolaryngology, Head and Neck Surgery, Tracheal Research Center, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Safavi-Naini
authors.affiliation: Dept. of Otolaryngology, Head and Neck Surgery, Tracheal Research Center, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Nasim
authors.initials: N
authors.lastname: Raad
authors.affiliation: Dept. of Otolaryngology, Head and Neck Surgery, Tracheal Research Center, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Jahangir
authors.initials: J
authors.lastname: Ghorbani
authors.affiliation: Dept. of Biostatistics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Samira
authors.initials: S
authors.lastname: Chaibakhsh
authors.affiliation: Dept. of Health of Iran, Expert of Non-communicable Disease, Cancer of CDC.
authors.forename: Rashid
authors.initials: R
authors.lastname: Ramezani-Daryasar
keywords: Incidence; NPC; Nasopharyngeal carcinoma; Trend