title: Computational fluid dynamics analysis and PIV validation of a bionic vortex flow pulsatile LVAD.
abstract: BACKGROUND
  Hemocompatibility is highly affected by the flow field in Left Ventricular Assistant Devices (LVAD).
  
  
  OBJECTIVE
  An asymmetric inflow and outflow channel arrangement with a 45° intersection angle with respect to the blood chamber is proposed to approximate the vascular structure of the aorta and left atrium on the left ventricle. The structure is expected to develop uninterruptible vortex flow state which is similar to the flow state in human left ventricle.
  
  
  METHODS
  The Computational Fluid Dynamics (CFD) asymmetric model is simulated using ANSYS workbench. To validate the velocity field calculated by CFD, a Particle Image Velocimetry (PIV) experiment is conducted.
  
  
  RESULTS
  The CFD results show that the proposed blood chamber could generate a shifting vortex flow that would be redirected to the aorta during ejection to form a persistent recirculating flow state, which is similar to the echocardiographic flow state in left ventricle. Both the PIV and the CFD results show the development of a persistent vortex during the pulsatile period. Comparison of the qualitative flow pattern and quantitative probed velocity histories in a pulsatile period shows a good agreement between the CFD and PIV data.
  
  
  CONCLUSIONS
  The goal of developing persistent quasi intra-ventricle vortex flow state in LVAD is realized.
authors.forename: Liang
authors.initials: L
authors.lastname: Xu
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
authors.forename: Lin
authors.initials: L
authors.lastname: Ye
authors.forename: Zhaopeng
authors.initials: Z
authors.lastname: Dong
mesh_terms: D001011:Aorta / Q000033:anatomy & histology / Q000502:physiology; D001701:Bionics; D001783:Blood Flow Velocity; D003198:Computer Simulation; D006352:Heart Ventricles / Q000033:anatomy & histology; D006353:Heart-Assist Devices; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D016276:Ventricular Function
keywords: Bionic vortex flow; computational fluid dynamics; left ventricular assist device; particle image velocimetry