title: Hypohidrosis in Individuals with Exertional Heat Injury: A Prospective Open Cohort Study.
abstract: BACKGROUND
  Hypohidrosis is a risk factor for developing heat-related illnesses.
  
  
  OBJECTIVE
  To determine the prevalence of hypohidrosis in heat injury.
  
  
  METHODS
  Soldiers from the Singapore Armed Forces who developed heat injury between January 1, 2012 and December 31, 2013 were invited to participate in the study. Subjects were induced to sweat through exercising in a temperature- and humidity-regulated room, and then atomized starch-iodine powder was administered over their whole body to detect hypohidrosis. If this was found to be present, investigations to elucidate the cause of anhidrosis were performed.
  
  
  RESULTS
  Out of 65 males, 30 consented to participation. One was excluded because an exogenous cause resulted in heat injury. Nine (31%) demonstrated hypohidrosis. Of these, 1 (11%) had miliaria profunda, 2 (22%) had acquired idiopathic generalized anhidrosis and 6 (67%) manifested a new phenotype which we termed acquired symmetrical hypohidrosis (ASH).
  
  
  CONCLUSIONS
  Thirty-one percent of healthy soldiers who developed heat injury had hypohidrosis. Concurrently, a new clinical phenotype of ASH was identified.
authors.affiliation: National Skin Centre, Singapore, Singapore.
authors.forename: Joel Hua-Liang
authors.initials: JH
authors.lastname: Lim
authors.forename: Wai Leong
authors.initials: WL
authors.lastname: Kok
authors.forename: Noreffendy
authors.initials: N
authors.lastname: Bin Ali
authors.forename: Wei-Sheng
authors.initials: WS
authors.lastname: Chong
authors.forename: Hong Liang
authors.initials: HL
authors.lastname: Tey
mesh_terms: D000293:Adolescent; D000328:Adult; D015444:Exercise; D018882:Heat Stress Disorders / Q000150:complications*; D006801:Humans; D007007:Hypohidrosis / Q000453:epidemiology*; D008297:Male; D008889:Military Personnel; D005082:Physical Exertion; D015995:Prevalence; D011446:Prospective Studies; D012846:Singapore; D055815:Young Adult