title: Auditory evoked potentials in patients with major depressive disorder measured by Emotiv system.
abstract: In a previous study (unpublished), Emotiv headset was validated for capturing event-related potentials (ERPs) from normal subjects. In the present follow-up study, the signal quality of Emotiv headset was tested by the accuracy rate of discriminating Major Depressive Disorder (MDD) patients from the normal subjects. ERPs of 22 MDD patients and 15 normal subjects were induced by an auditory oddball task and the amplitude of N1, N2 and P3 of ERP components were specifically analyzed. The features of ERPs were statistically investigated. It is found that Emotiv headset is capable of discriminating the abnormal N1, N2 and P3 components in MDD patients. Relief-F algorithm was applied to all features for feature selection. The selected features were then input to a linear discriminant analysis (LDA) classifier with leave-one-out cross-validation to characterize the ERP features of MDD. 127 possible combinations out of the selected 7 ERP features were classified using LDA. The best classification accuracy was achieved to be 89.66%. These results suggest that MDD patients are identifiable from normal subjects by ERPs measured by Emotiv headset.
authors.affiliation: Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha 410008, China.|School of Life and Environmental Science, Guilin University of Electronic Technology, No. 1 Jinji Road, Guilin 541004, China.
authors.forename: Dongcui
authors.initials: D
authors.lastname: Wang
authors.affiliation: Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha 410008, China.
authors.forename: Fongming
authors.initials: F
authors.lastname: Mo
authors.affiliation: Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha 410008, China.
authors.forename: Yangde
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: School of Electronic Engineering and Automation, Guilin University of Electronic Technology, No. 1 Jinji Road, Guilin 541004, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Yang
authors.affiliation: The Social Welfare Hospital of Guilin, No. 89 North Zhongshan Road, Guilin 541001, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.affiliation: School of Life and Environmental Science, Guilin University of Electronic Technology, No. 1 Jinji Road, Guilin 541004, China.
authors.forename: Zhencheng
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Xiangya Hospital, Central South University, No. 87 Xiangya Road, Changsha 410008, China.
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Zhao
mesh_terms: D000293:Adolescent; D000328:Adult; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000503:physiopathology*; D004569:Electroencephalography / Q000379:methods; D005072:Evoked Potentials, Auditory; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D055815:Young Adult
keywords: Emotiv system; event-related potential; major depressive disorder