title: Serum Amyloid A-Positive Hepatocellular Neoplasm: A New Type of Tumor Arising in Patients with Advanced Alcoholic Disease.
abstract: This chapter reviews a new type of hepatocellular neoplasm, serum amyloid A-positive hepatocellular neoplasm (SAA-HN), which arises in patients with advanced alcoholic liver disease such as cirrhosis. SAA-HNs share histological and immunohistochemical features with inflammatory hepatocellular adenoma, for example, a strong immunoreactivity for SAA. Clinicopathological features and issues regarding SAA-HN are reviewed with emphasis regarding its potential to develop into hepatocellular carcinoma.
authors.affiliation: Department of Human Pathology, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
authors.forename: Motoko
authors.initials: M
authors.lastname: Sasaki
authors.forename: Yasuni
authors.initials: Y
authors.lastname: Nakanuma
mesh_terms: D018248:Adenoma, Liver Cell / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D008108:Liver Diseases, Alcoholic / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D000685:Serum Amyloid A Protein / Q000235:genetics / Q000378:metabolism*
chemical_list: D000685:Serum Amyloid A Protein