title: Evaluation of three glucometers for whole blood glucose measurements at the point of care in preterm or low-birth-weight infants.
abstract: OBJECTIVE
  We evaluated three blood glucose self-monitoring for measuring whole blood glucose levels in preterm and low-birth-weight infants.
  
  
  METHODS
  Between December 1, 2012 and March 31, 2013, 230 blood samples were collected from 50 newborns, who weighed, ≤2,300 g or were ≤36 weeks old, in the the neonatal intensive care unit of Eulji University Hospital. Three blood glucose self-monitoring (A: Precision Pcx, Abbott; B: One-Touch Verio, Johnson & Johnson; C: LifeScan SureStep Flexx, Johnson & Johnson) were used for the blood glucose measurements. The results were compared to those obtained using laboratory equipment (D: Advia chemical analyzer, Siemens Healthcare Diagnostics Inc.).
  
  
  RESULTS
  The correlation coefficients between laboratory equipment and the three blood glucose self-monitoring (A, B, and C) were found to be 0.888, 0.884, and 0.900, respectively. For glucose levels≤60 mg/dL, the correlation coefficients were 0.674, 0.687, and 0.679, respectively. For glucose levels>60 mg/dL, the correlation coefficients were 0.822, 0.819, and 0.839, respectively. All correlation coefficients were statistically significant. And the values from the blood glucose self-monitoring were not significantly different from the value of the laboratory equipment , after correcting for each device's average value (P>0.05). When using laboratory equipment (blood glucose ≤60 mg/dL), each device had a sensitivity of 0.458, 0.604, and 0.688 and a specificity of 0.995, 0.989, and 0.989, respectively.
  
  
  CONCLUSIONS
  Significant difference is not found between three blood glucose self-monitoring and laboratory equipment. But correlation between the measured values from blood glucose self-monitoring and laboratory equipment is lower in preterm or low-birth-weight infants than adults.
authors.affiliation: Department of Pediatrics, Eulji University School of Medicine, Daejeon, Korea.
authors.forename: Joon Ho
authors.initials: JH
authors.lastname: Hwang
authors.affiliation: Department of Laboratory Medicine, Eulji University School of Medicine, Daejeon, Korea.
authors.forename: Yong-Hak
authors.initials: YH
authors.lastname: Sohn
authors.affiliation: Department of Occupational & Environmental Medicine, Eulji University School of Medicine, Daejeon, Korea.
authors.forename: Seong-Sil
authors.initials: SS
authors.lastname: Chang
authors.affiliation: Department of Pediatrics, Eulji University School of Medicine, Daejeon, Korea.
authors.forename: Seung Yeon
authors.initials: SY
authors.lastname: Kim
keywords: Blood glucose self-monitoring; Hypoglycemia; Low-birth-weight infant; Preterm