title: Survival rate comparisons amongst cervical cancer patients treated with an open, robotic-assisted or laparoscopic radical hysterectomy: A five year experience.
abstract: BACKGROUND
  The purpose of this retrospective study was to assess the 5-year survival outcomes of cervical cancer patients who underwent an, open radical hysterectomy (ORH), robotic-assisted radical hysterectomy (RRH) or laparoscopic radical hysterectomy (LRH) for the treatment of their disease.
  
  
  METHODS
  We conducted a review of all cervical cancer patients who were managed with an ORH, RRH or LRH.
  
  
  RESULTS
  Forty-nine patients were treated with LRH, 58 were managed via RRH and 39 patients underwent an ORH. The LRH (1.78 h) patients had a significantly shorter operative duration than the RRH (2.88 h) and ORH (2.39 h) subjects (p < 0.001). Blood loss was the highest in the ORH (475 cc) group (RRH = 207 cc and LRH = 312 cc) (P < 0.001). Moreover, the ORH (5.04 days) patients had a significantly longer hospital stay than the LRH (2.95 days) and RRH (2.50 day) subjects (P < 0.001). Kaplan-Meier survival analysis revealed a progression free survival (PFS) rate of 84.6% for the ORH group, 89.8% for the LRH group and 89.7% for the RRH patients (P = 0.271) at 60 months; overall survival was 92.3% for the ORH group, 95.9% for the LRH group and 96.6% for the RRH patients (P = 0.80).
  
  
  CONCLUSIONS
  The results from this study suggest that, irrespective of operative approach, patients who underwent a radical hysterectomy for early stage cervical cancer attained similar 5-year disease free and overall survival outcomes.
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA 92663, USA.
authors.forename: Alberto A
authors.initials: AA
authors.lastname: Mendivil
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA 92663, USA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Rettenmaier
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA 92663, USA.
authors.forename: Lisa N
authors.initials: LN
authors.lastname: Abaid
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA 92663, USA.
authors.forename: John V
authors.initials: JV
authors.lastname: Brown
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA 92663, USA.
authors.forename: John P
authors.initials: JP
authors.lastname: Micha
authors.affiliation: The Nancy Yeary Women's Cancer Research Foundation, Newport Beach, CA 92663, USA.
authors.forename: Katrina L
authors.initials: KL
authors.lastname: Lopez
authors.affiliation: Gynecologic Oncology Associates, Newport Beach, CA 92663, USA. Electronic address: bram@gynoncology.com.
authors.forename: Bram H
authors.initials: BH
authors.lastname: Goldstein
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy / Q000401:mortality*; D010535:Laparoscopy / Q000379:methods*; D008875:Middle Aged; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012371:Robotics / Q000379:methods*; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery
keywords: Cervical cancer; Endoscopic surgery; Open surgery; Outcomes; Radical hysterectomy