title: Anti-VEGF Therapy and the Retina: An Update.
abstract: Ocular angiogenesis and macular oedema are major causes of sight loss across the world. Aberrant neovascularisation, which may arise secondary to numerous disease processes, can result in reduced vision as a result of oedema, haemorrhage, and scarring. The development of antivascular endothelial growth factor (anti-VEGF) agents has revolutionised the treatment of retinal vasogenic conditions. These drugs are now commonly employed for the treatment of a plethora of ocular pathologies including choroidal neovascularisation, diabetic macular oedema, and retinal vein occlusion to name a few. In this paper, we will explore the current use of anti-VEGF in a variety of retinal diseases and the impact that these medications have had on visual outcome for patients.
authors.affiliation: The Royal Berkshire NHS Foundation Trust, Craven Road, Reading RG1 5AN, UK.
authors.forename: Vikas
authors.initials: V
authors.lastname: Tah
authors.affiliation: Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London EC1V 2PD, UK.
authors.forename: Harry O
authors.initials: HO
authors.lastname: Orlans
authors.affiliation: Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London EC1V 2PD, UK.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Hyer
authors.affiliation: Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London EC1V 2PD, UK.
authors.forename: Edward
authors.initials: E
authors.lastname: Casswell
authors.affiliation: Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London EC1V 2PD, UK.
authors.forename: Nizar
authors.initials: N
authors.lastname: Din
authors.affiliation: St George's University of London, Cranmer Terrace, London SW17 0RE, UK.
authors.forename: Vishnu
authors.initials: V
authors.lastname: Sri Shanmuganathan
authors.affiliation: Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London EC1V 2PD, UK.
authors.forename: Louise
authors.initials: L
authors.lastname: Ramskold
authors.affiliation: Moorfields Eye Hospital NHS Foundation Trust, 162 City Road, London EC1V 2PD, UK.
authors.forename: Saruban
authors.initials: S
authors.lastname: Pasu