title: Controllable in situ synthesis of silver nanoparticles on multilayered film-coated silk fibers for antibacterial application.
abstract: Layer-by-layer (LbL) assembly is a versatile technique for the preparation of multilayered polymeric films. However, fabrication of LbL polymetic film on silk for the in situ growth of high-density silver nanoparticles (AgNPs) has not been realized. Herein poly(acrylic acid) (PAA)/poly(dimethyldiallylammonium chloride) (PDDA) multilayers are constructed on silk via the LbL approach, subsequently serving as a 3-dimensional matrix for in situ synthesis of AgNPs. After 8 rounds of LbL assembly, the silk is fully covered with a layer of polymeric film. AgNPs with good crystalline structures could be in-situ generated in the silk-coated multilayers and their amount could be tailored by adjusting the bilayer numbers. The as-prepared silk could effectively kill the existing bacteria and inhibit the bacterial growth, demonstrating the antimicrobial activity. Moreover, the release of Ag(+) from the modified silk can last for 120 h, rendering the modified silk sustainable antimicrobial activity. This work may provide a novel method to prepare AgNPs-functionalized antimicrobial silk for potential applications in textile industry.
authors.affiliation: State Key Laboratory of Silkworm Genome Biology, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China; Chongqing Key Laboratory for Advanced Materials & Technologies of Clean Energies, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China; Institute for Clean Energy & Advanced Materials, Faculty of Materials & Energy, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China.
authors.forename: Mei
authors.initials: M
authors.lastname: Meng
authors.affiliation: State Key Laboratory of Silkworm Genome Biology, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China.
authors.forename: Huawei
authors.initials: H
authors.lastname: He
authors.affiliation: Chongqing Key Laboratory for Advanced Materials & Technologies of Clean Energies, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China; Institute for Clean Energy & Advanced Materials, Faculty of Materials & Energy, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China.
authors.forename: Jing
authors.initials: J
authors.lastname: Xiao
authors.affiliation: State Key Laboratory of Silkworm Genome Biology, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China.
authors.forename: Ping
authors.initials: P
authors.lastname: Zhao
authors.affiliation: Chongqing Key Laboratory for Advanced Materials & Technologies of Clean Energies, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China; Institute for Clean Energy & Advanced Materials, Faculty of Materials & Energy, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China.
authors.forename: Jiale
authors.initials: J
authors.lastname: Xie
authors.affiliation: State Key Laboratory of Silkworm Genome Biology, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China; Chongqing Key Laboratory for Advanced Materials & Technologies of Clean Energies, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China; Institute for Clean Energy & Advanced Materials, Faculty of Materials & Energy, Southwest University, 1 Tiansheng Road, Chongqing 400715, PR China. Electronic address: zslu@swu.edu.cn.
authors.forename: Zhisong
authors.initials: Z
authors.lastname: Lu
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D055664:Electrochemical Techniques; D004926:Escherichia coli / Q000187:drug effects; D053768:Metal Nanoparticles / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010316:Particle Size; D011095:Polyethylenes / Q000737:chemistry / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000737:chemistry / Q000494:pharmacology; D047011:Silk / Q000737:chemistry* / Q000494:pharmacology*; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013499:Surface Properties
chemical_list: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; D011095:Polyethylenes; D000644:Quaternary Ammonium Compounds; D047011:Silk; C041004:poly-N,N-dimethyl-N,N-diallylammonium chloride; D012834:Silver; C006903:carbopol 940
keywords: Antibacteria; Layer-by-layer assembly; Silk; Silver nanoparticles; Surface functionalization