title: Protein lysine acetylation in bacteria: Current state of the art.
abstract: Post-translational modifications of proteins are key events in cellular metabolism and physiology regulation. Lysine acetylation is one of the best studied protein modifications in eukaryotes, but, until recently, ignored in bacteria. However, proteomic advances have highlighted the diversity of bacterial lysine-acetylated proteins. The current data support the implication of lysine acetylation in various metabolic pathways, adaptation and virulence. In this review, we present a broad overview of the current knowledge of lysine acetylation in bacteria. We emphasize particularly the significant contribution of proteomics in this field.
authors.affiliation: CNRS, UMR 6270, Polymères, Biopolymères, Surfaces Laboratory, Mont-Saint-Aignan, France.|Normandie University, UR, France.|PISSARO proteomic facility, IRIB, Mont-Saint-Aignan, France.
authors.forename: Tassadit
authors.initials: T
authors.lastname: Ouidir
authors.affiliation: CNRS, UMR 6270, Polymères, Biopolymères, Surfaces Laboratory, Mont-Saint-Aignan, France.|Normandie University, UR, France.|PISSARO proteomic facility, IRIB, Mont-Saint-Aignan, France.
authors.forename: Takfarinas
authors.initials: T
authors.lastname: Kentache
authors.affiliation: CNRS, UMR 6270, Polymères, Biopolymères, Surfaces Laboratory, Mont-Saint-Aignan, France.|Normandie University, UR, France.|PISSARO proteomic facility, IRIB, Mont-Saint-Aignan, France.
authors.forename: Julie
authors.initials: J
authors.lastname: Hardouin
mesh_terms: D000107:Acetylation; D001419:Bacteria / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism*; D006801:Humans; D008239:Lysine / Q000378:metabolism; D053858:Metabolic Networks and Pathways; D011499:Protein Processing, Post-Translational; D040901:Proteomics
chemical_list: D001426:Bacterial Proteins; D008239:Lysine
keywords: Bacteria; Lysine acetylation; Microbiology