title: Development of Conventional Transarterial Chemoembolization for Hepatocellular Carcinomas in Japan: Historical, Strategic, and Technical Review.
abstract: OBJECTIVE
  This article reviews the development of transarterial chemoembolization (TACE) in Japan, particularly ethiodized oil-based conventional TACE, from historical, strategic, and technical points of view. We also present the current status of standardized conventional TACE.
  
  
  CONCLUSIONS
  Conventional TACE has been developed toward a more-selective and hemodynamic-conscious method, along with technical innovation and knowledge accumulation. Standardization of this method is necessary for further scientific evaluation.
authors.affiliation: 1 Dotter Interventional Institute, 3181 SW Sam Jackson Park Rd, L342, Portland, OR 97239.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Horikawa
authors.affiliation: 2 Department of Diagnostic Radiology, Fukuiken Saiseikai Hospital, Fukui, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Miyayama
authors.affiliation: 3 Department of Radiology, Hitachi General Hospital, Hitachi, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Irie
authors.affiliation: 4 Department of Radiology, National Defense Medical College, Tokorozawa, Japan.
authors.forename: Tatsumi
authors.initials: T
authors.lastname: Kaji
authors.affiliation: 5 Department of Diagnostic Radiology, National Cancer Center Hospital, Tokyo, Japan.
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Arai
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D002404:Catheterization; D016461:Chemoembolization, Therapeutic / Q000379:methods; D004998:Ethiodized Oil / Q000008:administration & dosage; D006801:Humans; D007564:Japan; D008113:Liver Neoplasms / Q000628:therapy*; D018579:Patient Selection
chemical_list: D000970:Antineoplastic Agents; D004998:Ethiodized Oil
keywords: Japanese; conventional transarterial chemoembolization; drug-eluting beads; hepatocellular carcinoma; transarterial chemoembolization