title: The Environmentally Benign form of Pesticide in Hydrodispersive Nanometric form with Improved Efficacy Against Adult Mosquitoes at Low Exposure Concentrations.
abstract: Permethrin, a poorly water-soluble synthetic pesticide belonging to the pyrethroid family, was formulated into water-dispersive nanometric form by rapid evaporation of pesticide loaded oil-in-water microemulsion. The mean hydrodynamic diameter of Nanopermethrin was found to be 199.01 ± 1.4 nm. The efficacy of the Nanopermethrin was comparatively investigated with its bulk form against 2-3 days old adult mosquitoes by WHO cone bioassay for 60 min. The median knockdown concentration of Culex tritaeniorhynchus, Culex quinquefasciatus and Aedes albopictus were found to be 7.20 × 10(4), 7.53 × 10(4), 0.42 × 10(3) mg/L for Bulk permethrin, and 0.98 × 10(4), 1.17 × 10(4), 0.05 × 10(3) mg/L for Nanopermethrin, respectively. The obtained results extrapolate the improved efficacy of Nanopermethrin even at low-level concentrations. Hence, the formulated Nanopermethrin will serve as an effective alternative pesticide in controlling the mosquito population with reduced environmental toxicity.
authors.affiliation: Centre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
authors.forename: A P B
authors.initials: AP
authors.lastname: Balaji
authors.affiliation: Centre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
authors.forename: Prabhakar
authors.initials: P
authors.lastname: Mishra
authors.affiliation: Centre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
authors.forename: R S
authors.initials: RS
authors.lastname: Suresh Kumar
authors.affiliation: Centre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
authors.forename: Abhijeet
authors.initials: A
authors.lastname: Ashu
authors.affiliation: Casali Center, Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel.
authors.forename: Katherine
authors.initials: K
authors.lastname: Margulis
authors.affiliation: Casali Center, Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel.
authors.forename: Shlomo
authors.initials: S
authors.lastname: Magdassi
authors.affiliation: Centre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India.
authors.forename: Amitava
authors.initials: A
authors.lastname: Mukherjee
authors.affiliation: Centre for Nanobiotechnology, VIT University, Vellore, Tamil Nadu, 632014, India. nchandrasekaran@vit.ac.in.
authors.forename: Natarajan
authors.initials: N
authors.lastname: Chandrasekaran
mesh_terms: D000330:Aedes; D000818:Animals; D003465:Culex; D004787:Environmental Pollution / Q000517:prevention & control; D007306:Insecticides; D049329:Nanostructures; D026023:Permethrin; D014867:Water
chemical_list: D007306:Insecticides; D014867:Water; D026023:Permethrin
keywords: Contact toxicity; Environmental safety; Knockdown; Nanopesticide; Permethrin; WHO cone bioassay