title: [Clinical and biochemical characteristics in patients with histology compatible with steatothepatitis in National Hospital Arzobispo Loayza, Lima, Peru, from 2010 to 2012].
abstract: OBJECTIVE
  Describe the clinical and biochemical characteristics of patients with histopathological findings compatible with steatohepatitis of HNAL patients between 2010-2012. Determine the frequency of alcoholic and non-alcoholic steatohepatitis, presence of metabolic syndrome and other factors associated to non-alcoholic steatohepatitis, its main indications for liver biopsy and biochemical characteristics according to the severity of the histological findings.
  
  
  METHODS
  We evaluated all histological slides of liver biopsies of the period between 2010-2012, of which, those with the diagnosis of steatohepatitis were selected. Their medical records were then reviewed.
  
  
  RESULTS
  32 patients met inclusion criteria. 28 were female and 4 male, the average age was 49±12 years. Two patients had a history of chronic alcohol consumption, representing the group of alcoholic steatohepatitis. The more frequent clinical finding in patients with NASH (non-alcoholic steatohepatitis), was obesity (37%). 50% of patients had AST/ALT ratio <1.
  
  
  CONCLUSIONS
  Among population studied, non-alcoholic steatohepatitis was more common than alcoholic steatohepatitis, being obesity the most associated factor.
authors.affiliation: Facultad de Medicina Alberto Hurtado. Universidad Peruana Cayetano Heredia. Lima, PerÚ.
authors.forename: Paola Hilda
authors.initials: PH
authors.lastname: Alegría Matos
authors.affiliation: Facultad de Medicina Alberto Hurtado. Universidad Peruana Cayetano Heredia. Lima, PerÚ.
authors.forename: Kelly Stephanie
authors.initials: KS
authors.lastname: Tafur Cabello
authors.affiliation: Departamento de GastroenterologÍa. Hospital Nacional Arzobispo Loayza. Lima, PerÚ.
authors.forename: Adelina
authors.initials: A
authors.lastname: Lozano Miranda
authors.affiliation: Departamento de NefrologÍa. Hospital Nacional Cayetano Heredia. Lima, PerÚ.
authors.forename: Cesar
authors.initials: C
authors.lastname: Loza Munarriz
authors.affiliation: Departamento de PatologÍa. Hospital Nacional Arzobispo Loayza. Lima, PerÚ.
authors.forename: Zenaida
authors.initials: Z
authors.lastname: Lozano Miranda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005235:Fatty Liver, Alcoholic / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D009765:Obesity / Q000150:complications; D010568:Peru; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D055815:Young Adult