title: The role of PET scan in monitoring the progression of fibrosing mediastinitis.
abstract: We present the case of a 31-year-old man who presented with acute chest pain. Computed tomography scan showed a mediastinal mass engulfing right main-stem bronchus and another mass surrounding descending aorta. Positron emission tomography (PET) scan showed high mass metabolic activity. Histopathological evaluation revealed fibroinflammatory scarring. He was diagnosed with idiopathic fibrosing mediastinitis, started on prednisone and tamoxifen treatment, and monitored with serial PET scans. Nine months after treatment initiation, paraaortic abnormality had resolved and mediastinal mass had regressed.
authors.affiliation: Department of Pulmonary, Critical Care and Sleep Medicine, The George Washington University, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA; Department of Pulmonary, Gulhane Military Medical Academy, General Tevfik Saglam Caddesi, Etlik, Ankara 06010, Turkey. Electronic address: drhaticekaya@yahoo.com.
authors.forename: Hatice
authors.initials: H
authors.lastname: Kaya
authors.affiliation: Department of Pulmonary, Critical Care and Sleep Medicine, The George Washington University, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA. Electronic address: katherine.flower@hotmail.com.
authors.forename: Katherine
authors.initials: K
authors.lastname: Rider
authors.affiliation: Department of Pulmonary, Critical Care and Sleep Medicine, The George Washington University, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA. Electronic address: chobot@gwmail.gwu.edu.
authors.forename: Alexander H
authors.initials: AH
authors.lastname: Cho
authors.affiliation: Department of Pathology, The George Washington University, 900 23rd Street NW, Washington, DC 20037, USA. Electronic address: aschwartz@mfa.gwu.edu.
authors.forename: Arnold
authors.initials: A
authors.lastname: Schwartz
authors.affiliation: Department of Pulmonary, Critical Care and Sleep Medicine, The George Washington University, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA. Electronic address: ghadah_alrehaili@hotmail.com.
authors.forename: Ghadah
authors.initials: G
authors.lastname: Alrehaili
authors.affiliation: Department of Pulmonary, Critical Care and Sleep Medicine, The George Washington University, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA. Electronic address: jahari@mfa.gwu.edu.
authors.forename: Jalil
authors.initials: J
authors.lastname: Ahari
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D018450:Disease Progression; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008482:Mediastinum / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography; D011241:Prednisone / Q000627:therapeutic use; D012598:Sclerosis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D020845:Selective Estrogen Receptor Modulators / Q000627:therapeutic use; D013629:Tamoxifen / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D020845:Selective Estrogen Receptor Modulators; D013629:Tamoxifen; D011241:Prednisone
keywords: Fibrosis; Mediastinitis; Monitoring; PET scan