title: Evaluating of Physiological Chemical Levels in Blood to Assess the Risk of Morbidity and Mortality of Ischemic Cardiovascular Disease.
abstract: In this study, a multiple linear regression model to evaluate the risk of morbidity and mortality of ischemic cardiovascular disease is demonstrated. In this model, predictor variables are selected from physiological chemicals in a blood test of the subjects. Meanwhile, the calculated risk score is selected as a response variable. Four major latent variables including hepatic, nephric, metabolic, and BMI (Body Mass Index) are revealed by performing statistical and principal component analysis for the collected survey data. The analyzed result also shows that the cardiac disorder is correlated with symptoms of abnormal BMI, hepatic disorder, nephric disorder, and metabolic disorder. Thus, the risk of morbidity and mortality of ischemic cardiovascular disease can be assessed from the proposed multiple regression model.
authors.affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health. guozhiping74@hotmail.com.|Luoyang Orthopedic-Traumatological Hospital, Zhengzhou 450000, Henan, China. guozhiping74@hotmail.com.
authors.forename: Junyan
authors.initials: J
authors.lastname: Teng
authors.affiliation: Henan Province People's Hospital, Zhengzhou 450003, Henan, China. wei_yp1234@163.com.
authors.forename: Yanping
authors.initials: Y
authors.lastname: Wei
authors.affiliation: Emergency Medical Rescue Center of Zhengzhou City, Zhengzhou 450000, Henan, China. zz120su@163.com.
authors.forename: Fengming
authors.initials: F
authors.lastname: Su
authors.affiliation: Luoyang Orthopedic-Traumatological Hospital, Zhengzhou 450000, Henan, China. guozhiping74@hotmail.com.
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Guo
authors.affiliation: The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health. gilman_zhong@hotmail.com.
authors.forename: Jing-Quan
authors.initials: JQ
authors.lastname: Zhong
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D001774:Blood Chemical Analysis; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000401:mortality*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000097:blood; D016014:Linear Models; D008107:Liver Diseases / Q000097:blood; D008297:Male; D008659:Metabolic Diseases / Q000097:blood; D008875:Middle Aged; D009017:Morbidity; D012307:Risk Factors
chemical_list: D015415:Biomarkers
keywords: cardiac disorder; hepatic disorder; morbidity and mortality; physiological chemicals; risk score