title: Occipital Nerve Stimulation for Migraine: Update from Recent Multicenter Trials.
abstract: Occipital nerve stimulation (ONS) continues to be investigated for the treatment of refractory chronic migraine. Results from case series and from prospective, sham-controlled clinical trials remain inconclusive regarding the efficacy of ONS for migraine treatment. Safety and implantation techniques require improvements since rates of lead migration, infection, and persistent stimulator-related pain continue to be high. Existing data justify further ONS trials with carefully chosen primary outcome(s), adequate statistical power, and improved surgical techniques.
authors.forename: Todd J
authors.initials: TJ
authors.lastname: Schwedt
authors.forename: A Laine
authors.initials: AL
authors.lastname: Green
authors.forename: David W
authors.initials: DW
authors.lastname: Dodick
mesh_terms: D003391:Cranial Nerves / Q000502:physiology / Q000601:surgery*; D004599:Electric Stimulation Therapy / Q000379:methods*; D006801:Humans; D008881:Migraine Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D015337:Multicenter Studies as Topic / Q000379:methods*; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D016896:Treatment Outcome