title: Coexistence of systemic lupus erythematosus, Hashimoto's thyroiditis, and bilateral breast cancer in the same patient: a random association?
abstract: Estrogens influence many physiological processes and play a crucial role in the development of several diseases, including autoimmune disorders and hormone-sensitive cancers. Systemic lupus erythematosus is one of the most common systemic autoimmune rheumatic diseases affecting young and middle-aged females. The coexistence of multiple autoimmune disorders is well recognized, whereas the association between systemic lupus erythematosus and malignancies, especially hormone-sensitive cancers, remains enigmatic. We report the unusual case of a middle-aged woman that presented with concomitance of lupus erythematosus, Hashimoto's thyroiditis, and bilateral breast cancer.
authors.affiliation: Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic University of Marche, Torrette-Ancona, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Molinelli
authors.affiliation: Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic University of Marche, Torrette-Ancona, Italy.
authors.forename: Katia
authors.initials: K
authors.lastname: Giuliodori
authors.affiliation: Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic University of Marche, Torrette-Ancona, Italy. Corresponding author: anna.campanati@gmail.com.
authors.forename: Anna
authors.initials: A
authors.lastname: Campanati
authors.affiliation: Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic University of Marche, Torrette-Ancona, Italy.
authors.forename: Valerio
authors.initials: V
authors.lastname: Brisigotti
authors.affiliation: Dermatological Clinic, Department of Clinical and Molecular Medicine, Polytechnic University of Marche, Torrette-Ancona, Italy.
authors.forename: Annamaria
authors.initials: A
authors.lastname: Offidani
mesh_terms: D001943:Breast Neoplasms / Q000150:complications*; D005260:Female; D050031:Hashimoto Disease / Q000150:complications*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged