title: Analysing Biological Rhythms in Fibromyalgia Syndrome.
abstract: OBJECTIVE
  This study evaluated biological rhythm disorders in patients with fibromyalgia syndrome (FMS).
  
  
  METHODS
  The study enrolled 82 patients with FMS and 82 controls. Pain intensity was evaluated using a visual analogue scale (VAS). The psychological conditions of the patients were evaluated using the Beck Depression Inventory (BDI). The Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN) was used to assess disturbances in biological rhythms (ie sleep, activity, social and eating patterns).
  
  
  RESULTS
  There was no difference between the two groups at baseline (all p > 0.05). The BDI, BRIAN total, sleep, activity, social, and eating scores were higher in patients with FMS than in the controls (all p < 0.001). Further, a significant correlation was found between biological rhythms and BDI scores (p < 0.001) and there were positive correlations between the VAS score and BRIAN total, sleep, and eating and BDI in patients with FMS (all p < 0.001).
  
  
  CONCLUSIONS
  There are marked biological rhythm disturbances in FMS. There is an important relationship between rhythm disorders and FMS. The disturbances in sleep, functional activities, social participation, and disordered rhythms like eating patterns show the need for a multidisciplinary approach to treating patients with FMS.
authors.affiliation: Bozok University Medical School, Department of Physical Medicine and Rehabilitation, Yozgat TR-66001, Turkey. drmehmetucar@msn.com.
authors.forename: M
authors.initials: M
authors.lastname: Ucar
authors.affiliation: Yozgat State Hospital, Department of Physical Medicine and Rehabilitation, Yozgat, Turkey.
authors.forename: Ü
authors.initials: Ü
authors.lastname: Sarp
authors.affiliation: Bozok University Medical School, Department of Psychiatry, Turkey.
authors.forename: A I
authors.initials: AI
authors.lastname: Gül
authors.affiliation: Bozok University Medical School, Department of Neurology, Yozgat, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Tanik
authors.affiliation: Şanlıurfa Education and Research Hospital, Department of Physical Medicine and Rehabilitation, Şanlıurfa, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Yetisgin
authors.affiliation: Yozgat State Hospital, Department of Orthopedics and Traumatology, Yozgat, Turkey.
authors.forename: H O
authors.initials: HO
authors.lastname: Arik
authors.affiliation: Yozgat State Hospital, Department of Physical Medicine and Rehabilitation, Yozgat, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Nas
authors.affiliation: Bozok University Medical School, Department of Cardiovascular Surgery, Yozgat, Turkey.
authors.forename: Y K
authors.initials: YK
authors.lastname: Yılmaz