title: Synthesis of highly strained bicyclic[3.n.1]alkenes by a metal-catalyzed Conia-ene reaction.
abstract: A high yielding metal-catalysed Conia-ene reaction of 2-acetylenic ketones for the synthesis of bicyclo[3.n.1]alkenes has been developed. This simple and efficient 6-endo-dig-cyclization protocol enables the synthesis of a wide variety of bicyclic systems, present in many natural products.
authors.affiliation: Division of Natural Product Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India. rchegondi@iict.res.in.
authors.forename: Shivakrishna
authors.initials: S
authors.lastname: Kallepu
authors.affiliation: Division of Natural Product Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India. rchegondi@iict.res.in.
authors.forename: Krishna Kumar
authors.initials: KK
authors.lastname: Gollapelli
authors.affiliation: Centre for X-ray Crystallography, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
authors.forename: Jagadeesh Babu
authors.initials: JB
authors.lastname: Nanubolu
authors.affiliation: Division of Natural Product Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India. rchegondi@iict.res.in.
authors.forename: Rambabu
authors.initials: R
authors.lastname: Chegondi