title: Antibody-Modified Reduced Graphene Oxide Films with Extreme Sensitivity to Circulating Tumor Cells.
abstract: An antibody-modified reduced graphene oxide (rGO) film with unexpected -extreme sensitivity to circulating tumor cells (CTCs) is reported. The antibody--modified rGO films efficiently capture CTCs from billions of blood cells and minimize the background of white blood cells, without complex microfluidic operations.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors.forename: Yingying
authors.initials: Y
authors.lastname: Li
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Qihang
authors.initials: Q
authors.lastname: Lu
authors.affiliation: Laboratory of Bio-Inspired Smart Interface Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Hongliang
authors.initials: H
authors.lastname: Liu
authors.affiliation: School of Chemistry and Environment, Beihang University, Beijing, 100191, P. R. China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Wang
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors.forename: Pengchao
authors.initials: P
authors.lastname: Zhang
authors.affiliation: Department of Urology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, P. R. China.
authors.forename: Huageng
authors.initials: H
authors.lastname: Liang
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Chemistry and Environment, Beihang University, Beijing, 100191, P. R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Jiang
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|Laboratory of Bio-Inspired Smart Interface Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Shutao
authors.initials: S
authors.lastname: Wang
mesh_terms: D055910:Antibodies, Immobilized / Q000737:chemistry* / Q000276:immunology / Q000378:metabolism; D000951:Antigens, Neoplasm / Q000276:immunology; D015815:Cell Adhesion Molecules / Q000276:immunology; D000071858:Epithelial Cell Adhesion Molecule; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D061986:MCF-7 Cells; D055595:Mechanical Phenomena; D008856:Microscopy, Fluorescence; D008958:Models, Molecular; D008968:Molecular Conformation; D009360:Neoplastic Cells, Circulating / Q000378:metabolism*; D010087:Oxides / Q000737:chemistry*; D017155:Wettability
chemical_list: D055910:Antibodies, Immobilized; D000951:Antigens, Neoplasm; D015815:Cell Adhesion Molecules; D000071858:Epithelial Cell Adhesion Molecule; D010087:Oxides; D006108:Graphite
keywords: circulating tumor cells; multimatching; reduced graphene oxide; sensitivity