title: Diagnostic value of urinary protein and creatinine in combination with renal ultrasound examination in early renal damage of patients with hypertension.
abstract: OBJECTIVE
  To evaluate the diagnostic value of urinary protein and creatinine in combination with renal Doppler ultrasound examination in early renal damage of patients with hypertension.
  
  
  METHODS
  One hundred twenty two hypertensive patients who were treated in our hospital from December 2013 to June 2014 were selected for this study, including 33, 41 and 48 cases of Stage I, Stage II and Stage III hypertension respectively. Meanwhile, 30 healthy subjects were selected as the control group. They received urinary protein, creatinine and renal Doppler ultrasound examination.
  
  
  RESULTS
  The urinary protein levels of Stage I, II and Stage III hypertensive patients were significantly different from that of the control group (p<0.05). Urinary creatinine levels were similar (p>0.05) in stage I and II but different from control (p<0.05) in stage III. Doppler ultrasound examination showed that Stage I hypertensive patients had similar renal longest diameter (RLD), renal parenchymal thickness (RPT) and ratio of RPT/renal sinus thickness to those of the control group (p>0.05), and RLDs of Stage II hypertensive patients and the control group were not significantly different (p>0.05).
  
  
  CONCLUSIONS
  Urinary protein and creatinine levels in combination with renal Doppler ultrasound examination could diagnose early renal damage in patients with hypertension.
authors.affiliation: Jihong Zhu, Huaihe Hospital of Henan University, Kaifeng 475000, P. R. China.
authors.forename: Jihong
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Ke Wen, Huaihe Hospital of Henan University, Kaifeng 475000, P. R. China.
authors.forename: Ke
authors.initials: K
authors.lastname: Wen
authors.affiliation: Hongwen He, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, P. R. China.
authors.forename: Hongwen
authors.initials: H
authors.lastname: He
keywords: Creatinine; Hypertension; Ultrasound examination; Urinary protein