title: Novel stilbene-based Fischer base analog of leuco-TAM - (2E,2'Z)-{2-(4-(E)-styrylphenyl)propane-1,3-diylidene}bis(1,3,3-trimethylindoline) - derivatives: synthesis and structural consideration by 1D NMR and 2D NMR spectroscopy.
abstract: We report the synthesis of a series of novel stilbene-based (St) Fischer base analogs of leuco-triarylmethane (LTAM) dyes by treating Fischer base with (E)-4-styrylbenzaldehyde derivatives. All St-LTAM molecules examined herein are characterized by 1D and 2D NMR. They were found to exhibit ZE configuration and isomerize to their diastereomers EE and ZZ in 2-3 h. They exhibit type I behavior of diastereomeric isomerization.
authors.affiliation: Department of Advanced Materials Chemistry, Korea University, Se-Jong, 339-700, Korea.
authors.forename: Sam-Rok
authors.initials: SR
authors.lastname: Keum
authors.affiliation: Department of Advanced Materials Chemistry, Korea University, Se-Jong, 339-700, Korea.
authors.forename: Hyun-Woo
authors.initials: HW
authors.lastname: Lim
keywords: 1H; COSY; Fischer base analogs of leuco-TAM dyes; HETCOR; HMBC; Heck reaction; NMR; NOESY; diastereomeric isomerization; malachite green; photochemotherapy agents