title: [The Effect of Preoperative Oral Rehydration on Hemodynamic Changes during Induction of Anesthesia and Intraoperative Fluid Management].
abstract: BACKGROUND
  Preoperative oral rehydration solution (ORS) prevents dehydration before surgery. Therefore taking enough ORS possibly reduces the hemodynamic changes during induction of anesthesia, and reduces the amount of fluid needed during anesthesia.
  
  
  METHODS
  Forty patients undergoing elective surgery were randomly assigned to two groups: drinking 1,500 ml ORS 6 to 2 hours before anesthesia (ORS group) and nothing by mouth from 6 hours before anesthesia (Control group). Anesthesia induction was performed using propofol and remifentanil. To evaluate the hemodynamic changes, hemodynamic parameters including heart rate, blood pressure, cardiac index (CI), and stroke volume variation (SVV) were recorded before induction, after propofol administration, and after remifentanil administration. Total urine volume and the amount of fluid were also recorded at the end of the anesthesia.
  
  
  RESULTS
  In ORS group, CI showed a significantly higher value after propofol administration (P = 0.046). SVV was significantly lower (P < 0.0001) and total amount of fluid during anesthesia was significantly reduced (P < 0.0001) in ORS group.
  
  
  CONCLUSIONS
  Preoperative oral rehydration increases circulating blood volume, it keeps high CI during induction of anesthesia, and reduces the amount of intraoperative fluid.
authors.forename: Mari
authors.initials: M
authors.lastname: Tsutsui
authors.forename: Sayaka
authors.initials: S
authors.lastname: Ishigaki
authors.forename: Ayana
authors.initials: A
authors.lastname: Kanaya
authors.forename: Saori
authors.initials: S
authors.lastname: Kawaguchi
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ogura
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D001794:Blood Pressure; D001826:Body Fluids; D004338:Drug Combinations; D005440:Fluid Therapy; D006439:Hemodynamics; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D010880:Piperidines / Q000008:administration & dosage; D015742:Propofol / Q000008:administration & dosage; D000077208:Remifentanil; D055815:Young Adult
chemical_list: D018686:Anesthetics, Intravenous; D004338:Drug Combinations; D010880:Piperidines; D000077208:Remifentanil; D015742:Propofol