title: Successful Treatment of Infectious Scleritis by Pseudomonas aeruginosa with Autologous Perichondrium Graft of Conchal Cartilage.
abstract: Infectious scleritis by Pseudomonas aeruginosa is a well-known vision-threatening disease. In particular, scleral trauma following pterygium surgery may increase the risk of sclera inflammation. Surgical debridement and repair is necessary in patients who do not respond to medical treatments, such as topical and intravenous antibiotics. We reports herein the effectiveness of an autologous perichondrium conchal cartilage graft for infectious scleritis caused by Pseudomonas aeruginosa. This procedure was performed on four eyes of four patients with infectious scleritis who had previously undergone pterygium surgery at Gyeongsang National University Hospital (GNUH), Jinju, Korea from December 2011 to May 2012. Pseudomonas aeruginosa was identified in cultures of necrotic scleral lesion before surgery. The conchal cartilage perichondrium graft was transplanted, and a conjunctival flap was created on the scleral lesion. The autologous perichondrium conchal cartilage graft was successful and visual outcome was stable in all patients, with no reports of graft failure or infection recurrence. In conclusion, autologous perichondrium conchal cartilage graft may be effective in surgical management of Pseudomonal infectious scleritis when non-surgical medical treatment is ineffective. Further studies in larger, diverse populations are warranted to establish the effectiveness of the procedure.
authors.affiliation: Department of Ophthalmology, Gyeongsang National University College of Medicine, Jinju, Korea.
authors.forename: Woong Sun
authors.initials: WS
authors.lastname: Yoo
authors.affiliation: Department of Ophthalmology, Gyeongsang National University College of Medicine, Jinju, Korea.
authors.forename: Che Ron
authors.initials: CR
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, Gyeongsang National University College of Medicine, Jinju, Korea.
authors.forename: Byung Jae
authors.initials: BJ
authors.lastname: Kim
authors.affiliation: Department of Otolaryngology, Gyeongsang National University College of Medicine, Jinju, Korea.
authors.forename: Seong Ki
authors.initials: SK
authors.lastname: Ahn
authors.affiliation: Department of Ophthalmology, Gyeongsang National University College of Medicine, Jinju, Korea.|Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.
authors.forename: Seong Wook
authors.initials: SW
authors.lastname: Seo
authors.affiliation: Department of Ophthalmology, Gyeongsang National University College of Medicine, Jinju, Korea.|Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.
authors.forename: Ji Myong
authors.initials: JM
authors.lastname: Yoo
authors.affiliation: Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.|Department of Ophthalmology, Gyeongsang National University College of Medicine, Jinju, Korea. maya12kim@naver.com.
authors.forename: Seong Jae
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D064592:Autografts; D002356:Cartilage / Q000601:surgery; D003141:Communicable Diseases; D003646:Debridement; D015818:Eye Infections, Bacterial / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D013508:Ophthalmologic Surgical Procedures; D011183:Postoperative Complications; D011552:Pseudomonas Infections / Q000382:microbiology / Q000628:therapy*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D011625:Pterygium / Q000601:surgery; D056910:Republic of Korea; D012590:Sclera / Q000601:surgery* / Q000637:transplantation; D015423:Scleritis / Q000382:microbiology / Q000628:therapy*; D013530:Surgical Wound Infection / Q000382:microbiology / Q000628:therapy*; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents
keywords: Pseudomonas aeruginosa; Scleritis; autograft; ear cartilage