title: Recent Advances in Genetic Technique of Microbial Report Cells and Their Applications in Cell Arrays.
abstract: Microbial cell arrays have attracted consistent attention for their ability to provide unique global data on target analytes at low cost, their capacity for readily detectable and robust cell growth in diverse environments, their high degree of convenience, and their capacity for multiplexing via incorporation of molecularly tailored reporter cells. To highlight recent progress in the field of microbial cell arrays, this review discusses research on genetic engineering of reporter cells, technologies for patterning live cells on solid surfaces, cellular immobilization in different polymers, and studies on their application in environmental monitoring, disease diagnostics, and other related fields. On the basis of these results, we discuss current challenges and future prospects for novel microbial cell arrays, which show promise for use as potent tools for unraveling complex biological processes.
authors.affiliation: Department of Bionano Technology, Gachon University, Gyeonggi 461-701, Republic of Korea.
authors.forename: Do Hyun
authors.initials: DH
authors.lastname: Kim
authors.affiliation: Department of Bionano Technology, Gachon University, Gyeonggi 461-701, Republic of Korea.
authors.forename: Moon Il
authors.initials: MI
authors.lastname: Kim
authors.affiliation: Department of Chemical and Biomolecular Engineering (BK21+ Program), Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.
authors.forename: Hyun Gyu
authors.initials: HG
authors.lastname: Park
mesh_terms: D001419:Bacteria / Q000166:cytology*; D005818:Genetic Engineering; D005821:Genetic Techniques / Q000639:trends*; D050296:Microbial Viability