title: Lipid-based nanocarriers for breast cancer treatment - comprehensive review.
abstract: Breast cancer is the second leading cancer-related disease as the most common non-cutaneous malignancy among women. Curative options for breast cancer are limited, therapeutically substantial and associated with toxicities. Emerging nanotechnologies exhibited the possibility to treat or target breast cancer. Among the nanoparticles, various lipid nanoparticles namely, liposomes, solid lipid nanoparticles, nanostructured lipid carriers and lipid polymer hybrid nanoparticles have been developed over the years for the breast cancer therapy and evidences are documented. Concepts are confined in lab scale, which needs to be transferred to large scale to develop active targeting nanomedicine for the clinical utility. So, the present review highlights the recently published studies in the development of lipid-based nanocarriers for breast cancer treatment.
authors.affiliation: a Department of Pharmaceutics , JSS College of Pharmacy, JSS University , Udhagamandalam , Tamil Nadu , India and.
authors.forename: Siddartha Venkata
authors.initials: SV
authors.lastname: Talluri
authors.affiliation: a Department of Pharmaceutics , JSS College of Pharmacy, JSS University , Udhagamandalam , Tamil Nadu , India and.
authors.forename: Gowthamarajan
authors.initials: G
authors.lastname: Kuppusamy
authors.affiliation: a Department of Pharmaceutics , JSS College of Pharmacy, JSS University , Udhagamandalam , Tamil Nadu , India and.
authors.forename: Veera Venkata Satyanarayana Reddy
authors.initials: VV
authors.lastname: Karri
authors.affiliation: a Department of Pharmaceutics , JSS College of Pharmacy, JSS University , Udhagamandalam , Tamil Nadu , India and.
authors.forename: Shashank
authors.initials: S
authors.lastname: Tummala
authors.affiliation: b Department of Biochemistry , JSS Medical College, JSS University , Mysore , Karnataka , India.
authors.forename: SubbaRao V
authors.initials: SV
authors.lastname: Madhunapantula
mesh_terms: D001943:Breast Neoplasms / Q000737:chemistry* / Q000188:drug therapy; D004337:Drug Carriers; D005260:Female; D006801:Humans; D008055:Lipids / Q000737:chemistry*; D008081:Liposomes; D053758:Nanoparticles / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology
chemical_list: D004337:Drug Carriers; D008055:Lipids; D008081:Liposomes
keywords: Breast cancer; lipid; lipid polymer hybrid nanoparticles; liposomes; nanostructured lipid carriers; solid lipid nanoparticles