title: Immediate and Long-Term Results of Drug-Eluting Stents in Mammary Artery Grafts.
abstract: Percutaneous intervention of a coronary graft is the treatment of choice when the graft fails. The objective is to report the long-term results of drug-eluting stents (DES) in mammary artery grafts (MAG). Patients who had been treated with DES for MAG in 27 centers were selected. The baseline and procedural clinical data were included prospectively, and the follow-up was performed with the patients, families, and medical records. Two hundred and sixty-eight patients were included: age 65.5 ± 10.1 years, diabetes 47.8%, ejection fraction 55.5 ± 14.9%.
  
  
  METHODS
  stable angina 28.4%, unstable angina 38.1%, non-ST-elevation myocardial infarction 21.6%, ST-elevation myocardial infarction 5.3%, and heart failure 6.7%; 1.19 ± 0.59 stents/patient were implanted measuring 18.8 ± 8.8 mm in length and 2.68 ± 0.35 mm in diameter. Rapamycin was used in 78 cases (29.1%), paclitaxel in 77 (28.7%), everolimus in 70 (26.1%), zotarolimus in 34 (12.7%), and biolimus in 9 (3.4%). All cases were successful except for 1 in which the patient died 30 minutes after the procedure. There were no other inhospital events. After a follow-up of 41 months (Q25: 23.7 to Q75: 57.8), 24 patients (9%) died of heart-related causes and 20 (7.5%) of noncardiac causes. Repeat revascularization was necessary in 31 cases, and in 1 additional patient, there was total occlusion, which was not treated. These 32 patients represented 11.9% of the total. In conclusion, the implantation of DES in MAG shows very high procedural success and also low long-term event rates.
authors.affiliation: Departments of Cardiology of Hospital de Cabueñes, Gijón, Spain. Electronic address: inigo.lozano@gmail.com.
authors.forename: Iñigo
authors.initials: I
authors.lastname: Lozano
authors.affiliation: Hospital Clínico de Valladolid, Valladoild, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Serrador
authors.affiliation: Hospital de San Juan, San Juan de Alicante, Spain.
authors.forename: Ramon
authors.initials: R
authors.lastname: Lopez-Palop
authors.affiliation: Policlínica Guipúzcoa, San Sebastian, Spain.
authors.forename: Garikoitz
authors.initials: G
authors.lastname: Lasa
authors.affiliation: Hospital Virgen de la Salud, Toledo, Spain.
authors.forename: Jose
authors.initials: J
authors.lastname: Moreu
authors.affiliation: Hospital Virgen de la Arrixaca, Murcia, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Pinar
authors.affiliation: Complejo Hospitalario de León, Leon, Spain.
authors.forename: Armando Perez
authors.initials: AP
authors.lastname: de Prado
authors.affiliation: Hospital Clínico, Madrid, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Alfonso
authors.affiliation: Hospital Clínico de Málaga, Malaga, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Jimenez Navarro
authors.affiliation: Hospital Virgen del Rocío, Sevilla, Spain.
authors.forename: Monica Fernandez
authors.initials: MF
authors.lastname: Quero
authors.affiliation: Hospital General de Alicante, Alicante, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Pineda
authors.affiliation: Hospital Clínico de Salamanca, Salamanca, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Martin Moreiras
authors.affiliation: Hospital de Cruces, Bilbao, Spain.
authors.forename: Koldobika
authors.initials: K
authors.lastname: Garcia San Roman
authors.affiliation: Hospital Infanta Cristina, Badajoz, Spain.
authors.forename: Jose R
authors.initials: JR
authors.lastname: Lopez Minguez
authors.affiliation: Hospital Central de Asturias, Oviedo, Spain.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Suarez Cuervo
authors.affiliation: Hospital General de Albacete, Albacete, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Gutierrez
authors.affiliation: Hospital Doce de Octubre, Madrid, Spain.
authors.forename: Felipe
authors.initials: F
authors.lastname: Hernandez
authors.affiliation: Hospital Meixoeiro, Vigo, Spain.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Baz
authors.affiliation: Hospital de La Princesa, Madrid, Spain.
authors.forename: Amparo
authors.initials: A
authors.lastname: Benedicto
authors.affiliation: Hospital de Galdakao, Bilbao, Spain.
authors.forename: Jose R
authors.initials: JR
authors.lastname: Rumoroso
authors.affiliation: Hospital de Bellvitge, Barcelona, Spain.
authors.forename: Joan A
authors.initials: JA
authors.lastname: Gomez-Hospital
authors.affiliation: Hospital Val'debron, Barcelona, Spain.
authors.forename: Vicens
authors.initials: V
authors.lastname: Serra
authors.affiliation: Hospital Marqués de Valdecilla, Santander, Spain.
authors.forename: Jose M
authors.initials: JM
authors.lastname: de la Torre
authors.affiliation: Complejo Hospitalario de Navarra, Pamplona, Spain.
authors.forename: Valeriano
authors.initials: V
authors.lastname: Ruiz-Quevedo
authors.affiliation: Hospital de Alcorcón, Madrid, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Botas
authors.affiliation: Hospital Puerta de Hierro, Madrid, Spain.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Fernandez
authors.affiliation: Hospital La Paz, Madrid, Spain.
authors.forename: Angel
authors.initials: A
authors.lastname: Sanchez-Recalde
mesh_terms: D000368:Aged; D054855:Drug-Eluting Stents; D000068338:Everolimus / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007387:Internal Mammary-Coronary Artery Anastomosis; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage; D020123:Sirolimus / Q000008:administration & dosage / Q000031:analogs & derivatives; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D000068338:Everolimus; C489443:zotarolimus; D017239:Paclitaxel; C518022:umirolimus; D020123:Sirolimus