title: Synthetic multivalency for biological applications.
abstract: Current directions and emerging possibilities under investigation for the integration of synthetic and semi-synthetic multivalent architectures with biology are discussed. Attention is focussed around multivalent interactions, their fundamental role in biology, and current and potential approaches in emulating them in terms of structure and functionality using synthetic architectures.
authors.affiliation: Conway Institute for Biomolecular and Biomedical Science, Belfield, Dublin 4, Ireland. eugene.mahon@ucd.ie.
authors.forename: Eugene
authors.initials: E
authors.lastname: Mahon
authors.affiliation: Adaptative Supramolecular Nanosystems Group, Institut Européen des Membranes, ENSCM/UMII/UMR-CNRS 5635, Pl. Eugène Bataillon, CC 047, 34095 Montpellier, Cedex 5, France. mihail-dumitru.barboiu@univ-montp2.fr.
authors.forename: Mihail
authors.initials: M
authors.lastname: Barboiu
mesh_terms: D056704:Adaptive Immunity; D000818:Animals; D032701:Biomimetics / Q000379:methods; D019020:Directed Molecular Evolution / Q000379:methods; D006801:Humans; D007113:Immunity, Innate; D008024:Ligands; D008958:Models, Molecular; D058615:Synthetic Biology / Q000379:methods
chemical_list: D008024:Ligands