title: Antimycoplasmic activity and seasonal variation of essential oil of Eugenia hiemalis Cambess. (Myrtaceae).
abstract: The purpose of this work was to study the chemical composition and antimycoplasmic and anticholinesterase activities of the essential oil of Eugenia hiemalis leaves collected throughout the year. A total of 42 compounds were identified by CG, and are present in almost every seasons. Sesquiterpenes were dominant (86.01-91.48%), and non-functionalised sesquiterpenes comprised the major fraction, which increased in the summer; monoterpenes were not identified. The major components were spathulenol (5.36-16.06%), δ-cadinene (7.50-15.93%), bicyclogermacrene (5.70-14.24%) and β-caryophyllene (4.80-9.43%). The highest oil yield was obtained in summer and autumn. Essential oils presented activity against three evaluated Mycoplasma strains, but no activity was observed in the anticholinesterase assay.
authors.affiliation: a Programa de Pós-graduação em Farmácia , Universidade Federal de Santa Catarina , Florianópolis , Brazil.
authors.forename: Gabriele Andressa
authors.initials: GA
authors.lastname: Zatelli
authors.affiliation: b Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Priscila
authors.initials: P
authors.lastname: Zimath
authors.affiliation: b Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Adrielli
authors.initials: A
authors.lastname: Tenfen
authors.affiliation: b Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Caio Maurício
authors.initials: CM
authors.lastname: Mendes de Cordova
authors.affiliation: c Laboratório de Cromatografia , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Dilamara Riva
authors.initials: DR
authors.lastname: Scharf
authors.affiliation: c Laboratório de Cromatografia , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Edésio Luiz
authors.initials: EL
authors.lastname: Simionatto
authors.affiliation: b Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Michele Debiasi
authors.initials: MD
authors.lastname: Alberton
authors.affiliation: a Programa de Pós-graduação em Farmácia , Universidade Federal de Santa Catarina , Florianópolis , Brazil.
authors.forename: Miriam
authors.initials: M
authors.lastname: Falkenberg
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000068856:Eugenia / Q000737:chemistry*; D039821:Monoterpenes / Q000737:chemistry*; D009174:Mycoplasma / Q000187:drug effects; D009822:Oils, Volatile / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D000081223:Polycyclic Sesquiterpenes; D012621:Seasons; D012717:Sesquiterpenes / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D039821:Monoterpenes; D009822:Oils, Volatile; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C000607799:delta-cadinene; C013258:spathulenol; C024714:caryophyllene
keywords: Eugenia hiemalis; Mycoplasma; antibacterial; essential oil; seasonal variation