title: Current Concepts in the Use of Voluma, Volift, and Volbella.
abstract: BACKGROUND
  Hyaluronic acids (HAs) are very popular temporary fillers with a very good safety record. Improvements and adaptations in clinical use are continuing.
  
  
  METHODS
  We have assessed the available literature to investigate the relatively new Vycross technology that uses a mixture of high- and low-molecular-weight HAs with a relatively low but varying HA concentration with enhanced cross-linking to produce a number of products that have differing clinical indications.
  
  
  RESULTS
  Voluma has the highest HA concentration at 20 mg/mL, a high G prime translating into lift capacity and cohesivity keeping the product capable to lift vertically adding structure, form, and volume, whereas Volbella has much lower concentration at 15 mg/mL, a lower G prime and cohesivity allowing it to be used in more a horizontal spreading fashion enabling a superficial approach to lips, lines, and more subtle depressions. Volift at 17.5 mg/mL HA is half way between the 2 other products, allowing more subtle lift capacity but retaining an element of spread making it a useful agent for the perioral region in general and in the treatment of fine lines.
  
  
  CONCLUSIONS
  A range of products has been released that allows different components of facial structure, volume, and lines to be adequately addressed.
authors.affiliation: Clayton and Carlton, Victoria, Australia; and Montreal, Quebec, and Calgary, Alberta, Canada From the Monash University; The Skin and Cancer Foundation; Westmount Institute of Plastic Surgery; Victoria Park MediSpa; St. Mary's Hospital, McGill University; and Remington Laser Dermatology Centre.
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Goodman
authors.forename: Arthur
authors.initials: A
authors.lastname: Swift
authors.forename: B Kent
authors.initials: BK
authors.lastname: Remington
mesh_terms: D001672:Biocompatible Materials / Q000008:administration & dosage*; D003357:Cosmetic Techniques; D005145:Face; D006801:Humans; D007267:Injections; D012060:Rejuvenation; D015361:Rhytidoplasty / Q000379:methods*; D015595:Skin Aging
chemical_list: D001672:Biocompatible Materials