title: Disparities in conditional net survival among non-Hodgkin lymphoma survivors: a population-based analysis.
abstract: We evaluated the association of baseline prognostic factors with conditional net survival among survivors of six subtypes non-Hodgkin lymphoma using the SEER program data from 2000-2012. Among 2-year survivors, further prognosis markedly improved in Burkitt's (BL) and diffuse large B-cell lymphoma (DLBCL), and became the same as for follicular lymphoma (5-year net survival ≥ 85%). Mantle cell lymphoma (MCL) demonstrated the worst prognosis of all studied histologies up to 5 years of survivorship. Age and stage lost prognostic significance in BL within 2 years from diagnosis. Racial disparities in net survival disappeared within 2 years for all subtypes, except in chronic lymphocytic leukemia, where black patients had persistently worse prognosis, and in MCL, where they had unexpectedly better prognosis than other races after 2 years. Many baseline factors may lose their initial prognostic value for lymphoma survivors, which should be considered when counseling patients about their prognosis and long-term surveillance.
authors.affiliation: a Department of Medicine , University of Florida , Gainesville , FL , USA ;
authors.forename: Yazan
authors.initials: Y
authors.lastname: Migdady
authors.affiliation: b University of Massachusetts Medical School , Worcester , MA , USA ;|c Memorial Hospital of Rhode Island , Pawtucket , RI , USA ;
authors.forename: Mohammed
authors.initials: M
authors.lastname: Salhab
authors.affiliation: a Department of Medicine , University of Florida , Gainesville , FL , USA ;
authors.forename: Nam H
authors.initials: NH
authors.lastname: Dang
authors.affiliation: a Department of Medicine , University of Florida , Gainesville , FL , USA ;
authors.forename: Merry J
authors.initials: MJ
authors.lastname: Markham
authors.affiliation: c Memorial Hospital of Rhode Island , Pawtucket , RI , USA ;|d The Warren Alpert Medical School of Brown University , Providence , RI , USA.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Olszewski
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011159:Population Surveillance; D011379:Prognosis; D018426:SEER Program; D017741:Survivors; D055815:Young Adult
keywords: Burkitt lymphoma; conditional survival; diffuse large B-cell lymphoma; epidemiology; non-Hodgkin lymphoma; relative survival