title: Clinical Features and Surgical Treatment of Aggressive Meningiomas.
abstract: OBJECTIVE
  To explore the clinical features and surgical treatment of aggressive meningiomas (AMs).
  
  
  METHODS
  Samples from 55 patients with AMs were analyzed, and their clinical characteristics, molecular biological mechanism, and surgical treatment were studied in combination with the literature.
  
  
  RESULTS
  The main clinical and imaging features of AMs included manifestations of local structures invaded by tumors, frequently irregular or flat tumors in shape, more obvious cerebral edema surrounding the tumors, seldom calcification of tumor, more frequent and typical dural tail sign, often absent white or black ring sign, partial or complete occlusion of venous sinus and hyperplasia and destruction of local skull. Simpson I resection was achieved in 31 cases, II in 13, III-IV in 11. No severe complications and death occurred after operation.
  
  
  CONCLUSIONS
  AMs have prominent clinical features. Appropriate surgery can provide a good therapeutic effect.
authors.affiliation: Qilu Hospital of Shandong University, Brain Science Research Institute of Shandong University, Department of Neurosurgery, Jinan, PR China.
authors.forename: Hongwei
authors.initials: H
authors.lastname: Wang
authors.forename: Shujiang
authors.initials: S
authors.lastname: Niu
authors.forename: Chuanwei
authors.initials: C
authors.lastname: Wang
authors.forename: Yuguang
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D008579:Meningioma / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D016896:Treatment Outcome