title: Exercise and Fatigue in Adolescent and Young Adult Survivors of Hodgkin Lymphoma: A Report from the Children's Oncology Group.
abstract: Fatigue is a significant problem for adolescent and young adult (AYA) Hodgkin lymphoma (HL) survivors. The relationship between exercise and fatigue is complex. This study explored the trajectory of and the relationship between exercise and fatigue over 36 months post-therapy in a cohort of 103 AYA-aged HL survivors treated on Children's Oncology Group (COG) study AHOD0031. Descriptive statistics and generalized estimating equations were used in this secondary data analysis. Exercise and fatigue improved over time but were unrelated; amount of exercise at end of therapy predicted amount of exercise at 12 (p = 0.02) and 36 (p = 0.0008) months post-therapy.
authors.affiliation: Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles , Los Angeles, California.
authors.forename: Catherine Fiona
authors.initials: CF
authors.lastname: Macpherson
authors.affiliation: School of Nursing, University of Minnesota School of Nursing , Minneapolis, Minnesota.
authors.forename: Mary C
authors.initials: MC
authors.lastname: Hooke
authors.affiliation: Vanderbilt University and Vanderbilt-Ingram Cancer Center , Nashville, Tennessee.
authors.forename: Debra L
authors.initials: DL
authors.lastname: Friedman
authors.affiliation: Vanderbilt University Medical Center and School of Nursing ; Nashville, Tennessee.
authors.forename: Kristin
authors.initials: K
authors.lastname: Campbell
authors.affiliation: Department of Pediatric Oncology, Palmetto Health Children's Hospital , Columbia, South Carolina.
authors.forename: Janice
authors.initials: J
authors.lastname: Withycombe
authors.affiliation: Brown University and Hasbro Children's Hospital ; Providence, Rhode Island.
authors.forename: Cindy L
authors.initials: CL
authors.lastname: Schwartz
authors.affiliation: New York-Presbyterian Morgan Stanley Children's Hospital and Columbia University Medical Center , New York.
authors.forename: Kara
authors.initials: K
authors.lastname: Kelly
authors.affiliation: Department of Biostatistics, University of Nebraska Medical Center Department of Biostatistics , Omaha, Nebraska.
authors.forename: Jane
authors.initials: J
authors.lastname: Meza
mesh_terms: D000293:Adolescent; D000328:Adult; D015444:Exercise / Q000502:physiology*; D005221:Fatigue / Q000209:etiology* / Q000473:pathology; D005260:Female; D006689:Hodgkin Disease / Q000150:complications*; D006801:Humans; D008297:Male; D012307:Risk Factors; D017741:Survivors; D055815:Young Adult
keywords: Hodgkin lymphoma; exercise; fatigue; survivorship