title: Electrical Stimulation Able to Trigger Locomotor Spinal Circuits Also Induces Dorsal Horn Activity.
abstract: OBJECTIVE
  Investigate whether electrical stimulation of the spinal cord adapted to trigger locomotor patterns additionally influences dorsal horn networks.
  
  
  METHODS
  An in vitro model of isolated neonatal rat spinal cord was used to repetitively deliver electrical stimuli to lumbar dorsal roots and record from homolateral lumbar dorsal roots and ventral roots.
  
  
  RESULTS
  Repetitive electrical lumbar dorsal root stimulation can affect both locomotor rhythms derived from ventral neuronal circuits and activity from dorsal neuronal circuits.
  
  
  CONCLUSIONS
  These data suggest that neuro-electrostimulation protocols can simultaneously activate functionally distinct spinal neuronal circuits.
authors.affiliation: Neuroscience Department, International School for Advanced Studies (SISSA), Trieste, Italy.|SPINAL (Spinal Person Injury Neurorehabilitation Applied Laboratory), Istituto di Medicina Fisica e Riabilitazione (IMFR), Udine, Italy.
authors.forename: Nejada
authors.initials: N
authors.lastname: Dingu
authors.affiliation: Institute of Neuroscience, Université catholique de Louvain (UCL), Brussels, Belgium.
authors.forename: Ronald
authors.initials: R
authors.lastname: Deumens
authors.affiliation: Neuroscience Department, International School for Advanced Studies (SISSA), Trieste, Italy.|SPINAL (Spinal Person Injury Neurorehabilitation Applied Laboratory), Istituto di Medicina Fisica e Riabilitazione (IMFR), Udine, Italy.
authors.forename: Giuliano
authors.initials: G
authors.lastname: Taccola
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D000831:Animals, Newborn; D001703:Biophysics; D004558:Electric Stimulation; D066298:In Vitro Techniques; D016014:Linear Models; D009415:Nerve Net / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013116:Spinal Cord / Q000033:anatomy & histology* / Q000502:physiology; D066148:Spinal Cord Dorsal Horn / Q000502:physiology*; D013126:Spinal Nerve Roots / Q000502:physiology*; D013997:Time Factors
keywords: Central pattern generator; fictive locomotion; isolated spinal cord; neurorehabilitation; rat