title: Copper N-Heterocyclic Carbene Complexes As Active Catalysts for the Synthesis of 2-Substituted Oxazolines from Nitriles and Aminoalcohols.
abstract: The reaction between nitriles and aminoalcohols to access 2-substituted oxazolines was investigated. Using copper-NHC complexes, various nitriles were successfully converted into the corresponding oxazolines, under milder and less wasteful conditions than those of previously reported methods.
authors.affiliation: EaStCHEM School of Chemistry, University of St. Andrews , St. Andrews, KY16 9ST, U.K.
authors.forename: Michael
authors.initials: M
authors.lastname: Trose
authors.affiliation: EaStCHEM School of Chemistry, University of St. Andrews , St. Andrews, KY16 9ST, U.K.
authors.forename: Faïma
authors.initials: F
authors.lastname: Lazreg
authors.affiliation: EaStCHEM School of Chemistry, University of St. Andrews , St. Andrews, KY16 9ST, U.K.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Lesieur
authors.affiliation: EaStCHEM School of Chemistry, University of St. Andrews , St. Andrews, KY16 9ST, U.K.
authors.forename: Catherine S J
authors.initials: CS
authors.lastname: Cazin
mesh_terms: D000605:Amino Alcohols / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000605:Amino Alcohols; D006571:Heterocyclic Compounds; D009570:Nitriles; D009942:Organometallic Compounds; D010080:Oxazoles; C030011:carbene; D003300:Copper; D008697:Methane