title: Can preoperative 3-T MRI predict nipple-areolar complex involvement in patients with breast cancer?
abstract: OBJECTIVE
  To evaluate the diagnostic performances of preoperative 3-T breast MRI for predicting nipple-areolar complex (NAC) involvement.
  
  
  METHODS
  We analyzed the predictors of NAC involvement in breast cancer, with diagnostic performances.
  
  
  RESULTS
  Among the 403 patients, 43 cases were surgically confirmed for NAC involvement. For predicting NAC involvement, sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 60.5%, 87.5%, 36.6%, 94.9%, and 84.6%, respectively. Continuity to NAC, unilateral enhancement of NAC and thickening of NAC were significant magnetic resonance findings predictive of NAC involvement.
  
  
  CONCLUSIONS
  Preoperative 3-T breast MRI is a useful method to predict NAC involvement in breast cancer patients.
authors.affiliation: Department of Radiology, Ewha Womans University, School of Medicine, Seoul, Korea.
authors.forename: Jooyeon
authors.initials: J
authors.lastname: Cho
authors.affiliation: Department of Radiology, Ewha Womans University, School of Medicine, Seoul, Korea. Electronic address: aqua0724@ewha.ac.kr.
authors.forename: Jin
authors.initials: J
authors.lastname: Chung
authors.affiliation: Department of Radiology, Ewha Womans University, School of Medicine, Seoul, Korea.
authors.forename: Eun-Suk
authors.initials: ES
authors.lastname: Cha
authors.affiliation: Department of Radiology, Ewha Womans University, School of Medicine, Seoul, Korea.
authors.forename: Jee Eun
authors.initials: JE
authors.lastname: Lee
authors.affiliation: Department of Radiology, Ewha Womans University, School of Medicine, Seoul, Korea.
authors.forename: Jeoung Hyun
authors.initials: JH
authors.lastname: Kim
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009558:Nipples / Q000473:pathology*; D011300:Preoperative Care / Q000379:methods*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
keywords: 3 T; Breast; Breast MRI; Breast cancer; Nipple–areolar complex