title: Effect of low-level laser therapy on orthodontic tooth movement into bone-grafted alveolar defects.
abstract: BACKGROUND
  The objective of this study was to investigate the effect of low-level laser therapy (LLLT) on the rate of orthodontic tooth movement (OTM) into bone-grafted alveolar defects based on different healing states.
  
  
  METHODS
  Ten male beagles were randomly allocated to 3 groups: group C, OTM alone as a control; group G, OTM into the grafted defects; group GL, OTM into the grafted defects with LLLT. The maxillary second premolars were protracted into the defects for 6 weeks, immediately (G-0 and GL-0) and at 2 weeks (G-2 and GL-2) after surgery. The defects were irradiated with a diode laser (dose, 4.5 J/cm(2)) every other day for 2 weeks. The rates of OTM and alveolar bone apposition, and maturational states of the defects were analyzed by histomorphometry, microcomputed tomography, and histology.
  
  
  RESULTS
  The total amounts of OTM and new bone apposition rates were decreased by LLLT, with increased bone mineral density and trabecular maturation in the defects. Group GL-2 had the slowest movement with root resorption in relation to less woven bone in the hypermatured defect.
  
  
  CONCLUSIONS
  LLLT significantly decreased the rate of OTM into the bone-grafted surgical defects by accelerating defect healing and maturation, particularly when the start of postoperative OTM was delayed.
authors.affiliation: Clinical fellow, Department of Orthodontics, Dental Hospital, Kyung Hee University, Seoul, Korea.
authors.forename: Kyung-A
authors.initials: KA
authors.lastname: Kim
authors.affiliation: Postgraduate student, Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea.
authors.forename: Eun-Kyung
authors.initials: EK
authors.lastname: Choi
authors.affiliation: Assistant professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyung Hee University, Seoul, Korea.
authors.forename: Joo-Young
authors.initials: JY
authors.lastname: Ohe
authors.affiliation: Assistant professor, Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea.
authors.forename: Hyo-Won
authors.initials: HW
authors.lastname: Ahn
authors.affiliation: Associate professor, Department of Orthodontics, School of Dentistry, Kyung Hee University, Seoul, Korea. Electronic address: ksj113@khu.ac.kr.
authors.forename: Su-Jung
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D000539:Alveolar Process / Q000528:radiation effects* / Q000601:surgery; D000818:Animals; D015519:Bone Density / Q000528:radiation effects; D001857:Bone Matrix / Q000637:transplantation; D001861:Bone Regeneration / Q000528:radiation effects; D016723:Bone Remodeling / Q000528:radiation effects; D018786:Bone Substitutes / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods*; D004285:Dogs; D005456:Fluorescent Dyes; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008439:Maxillary Diseases / Q000532:radiotherapy* / Q000601:surgery; D010012:Osteogenesis / Q000528:radiation effects; D011897:Random Allocation; D014087:Tooth Movement Techniques / Q000379:methods*; D020390:Tooth Socket / Q000528:radiation effects / Q000601:surgery; D055114:X-Ray Microtomography / Q000379:methods
chemical_list: D018786:Bone Substitutes; D005456:Fluorescent Dyes