title: [The Original Formulation for Toso-shu (Tusujiu), Created by the 3rd Century Chinese Physician, Hua Tuo].
abstract: The original formulation for "Tusujiu," which Japanese people still consume on the morning of January 1st, was created by Hua Tuo, but has not been studied in detail. The book Huatuo Shenyi Bizhuan, found in 1918, describes a concoction, "Biyijiu," that shows great similarity to the current Tusujiu; the ingredients for Biyijiu being rhubarb, atractylodes rhizome, cinnamon bark, platycodon root, zanthoxylum fruit, processed aconite root and smilax rhizome. The procedures for preparing and drinking it are to "pound the ingredients and then put them into a silk bag dyed with madder. During the daytime of the last day of the year, hang the bag in a well to soften the powder. Take the bag out early in the morning of the next day, the first day of the year. Heat the bag in fermented liquor until simmering. Drink the liquid with all family members, doing so while facing east. If one person drinks it, there will be no disease in the family. If the whole family drinks it, there will be no disease in their neighborhood in an area of one square 'li'. In this study, to determine the original formulation for Tusujiu, we examined a number of ancient medical texts from the 3rd to the 13th century that discuss Biyijiu and Tusujiu. As a result, we concluded that "Biyijiu" is likely to be the original formulation developed by Hua Tuo.
authors.forename: Chika
authors.initials: C
authors.lastname: Mouri
authors.forename: Masayuki
authors.initials: M
authors.lastname: Mikage
mesh_terms: D031174:Atractylodes; D002626:Chemistry, Pharmaceutical; D002935:Cinnamomum zeylanicum; D004365:Drugs, Chinese Herbal; D007564:Japan; D008516:Medicine, Chinese Traditional; D031238:Platycodon; D012250:Rheum; D027343:Rhizome; D032106:Zanthoxylum
chemical_list: D004365:Drugs, Chinese Herbal