title: [Antibiotic susceptibility of bacteria isolated from diabetic foot infections and prospects for empiric antibiotic therapy in Ouagadougou (Burkina Faso)].
abstract: BACKGROUND
  The aim of this study was to study the antibiotic susceptibility of bacteria isolated from diabetic foot infections to help improve empiric antibiotic prescription in Ouagadougou, where bacteriological testing is rarely possible.
  
  
  METHODS
  This cross-sectional study took place from July 1, 2011, to June 30, 2012, in the departments of internal medicine and general and gastrointestinal surgery in the Yalgado Ouédraogo teaching hospital. Bacteria were isolated from diabetic foot infections and their antibiotic sensitivity was tested by the qualitative method (Kirby-Bauer).
  
  
  RESULTS
  The study included 64 patients, with a median age of 57 years (interquartile range: 48-75) and a M/F sex ratio of 1.37. Among them, 39 had received antibiotics before hospitalization. Among the 71 samples, 62 cultures (87%) were positive: 53 for a single microbe (85%) and 9 for two microbes (15%). Microorganisms were mainly aerobic and anaerobic Gram-positive cocci (76%), including Staphylococcus aureus (SA) (33%) and Streptococcus spp (18%). These Gram-positive cocci were highly sensitive to amoxicillin-clavulanic acid and oxacillin. No methicillin-resistant SA (MRSA) were isolated. Enterobacteriaceae (24 %) were highly susceptible to imipenem and ticarcillin, but not to ceftriaxone or ciprofloxacin. No extended-spectrum beta-lactamase Enterobacteriaceae (ESBL) were isolated. Pseudomonas aeruginosa was highly susceptible to ciprofloxacin and imipenem.
  
  
  CONCLUSIONS
  Despite our study's limitations, our findings show that most diabetic foot infections can be successfully treated with standard antibiotics.
authors.affiliation: UFR/SDS université de Ouagadougou, BP 7021, Ouagadougou, Burkina Faso, CHU Yalgado Ouédraogo, BP 7022, Ouagadougou, Burkina Faso.
authors.forename: O
authors.initials: O
authors.lastname: Guira
authors.affiliation: UFR/SDS université de Ouagadougou, BP 7021, Ouagadougou, Burkina Faso, CHU Yalgado Ouédraogo, BP 7022, Ouagadougou, Burkina Faso.
authors.forename: H
authors.initials: H
authors.lastname: Tiéno
authors.affiliation: CHU Yalgado Ouédraogo, BP 7022, Ouagadougou, Burkina Faso.
authors.forename: Y
authors.initials: Y
authors.lastname: Sagna
authors.affiliation: INSSA, Bobo Dioulasso, Burkina Faso, CHU Souro Sanou, Bobo Dioulasso, Burkina Faso.
authors.forename: T M
authors.initials: TM
authors.lastname: Yaméogo
authors.affiliation: CHU Yalgado Ouédraogo, BP 7022, Ouagadougou, Burkina Faso.
authors.forename: L
authors.initials: L
authors.lastname: Zoungrana
authors.affiliation: CHU Yalgado Ouédraogo, BP 7022, Ouagadougou, Burkina Faso.
authors.forename: S
authors.initials: S
authors.lastname: Traoré
authors.affiliation: CHU Yalgado Ouédraogo, BP 7022, Ouagadougou, Burkina Faso.
authors.forename: I
authors.initials: I
authors.lastname: Diallo
authors.affiliation: CHU Yalgado Ouédraogo, BP 7022, Ouagadougou, Burkina Faso.
authors.forename: D
authors.initials: D
authors.lastname: Yanogo
authors.affiliation: UFR/SDS université de Ouagadougou, BP 7021, Ouagadougou, Burkina Faso, CHU Yalgado Ouédraogo, BP 7022, Ouagadougou, Burkina Faso.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Drabo
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002050:Burkina Faso; D003430:Cross-Sectional Studies; D017719:Diabetic Foot / Q000150:complications / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012874:Skin Diseases, Infectious / Q000209:etiology / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents
keywords: Burkina Faso; Diabetic foot; antibiotic susceptibility; bacteria