title: Calcium-Catalyzed Dynamic Multicomponent Reaction.
abstract: The reversible formation of covalent bonds enabled by the remarkably high Lewis acidity of our calcium-based catalyst system was used for the development of a new type of multicomponent reaction. Accordingly, a pharmacologically interesting bicyclic amine was amplified from a highly efficient dynamic equilibrium. The product is formed with full diastereoselectivity, and as typical for our calcium-catalyzed reactions, precautions for the exclusion of air and moisture are unnecessary.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University , 52074 Aachen, Germany.
authors.forename: Shuang
authors.initials: S
authors.lastname: Gao
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University , 52074 Aachen, Germany.
authors.forename: Tobias
authors.initials: T
authors.lastname: Stopka
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University , 52074 Aachen, Germany.
authors.forename: Meike
authors.initials: M
authors.lastname: Niggemann