title: Clinical Trials with Oncolytic Viruses: Current and Future Prospects.
abstract: Reviewing the research in the field of oncolytic virus therapy (OVT) of the past two decades, it is inspiring to see the enormous amount of success accomplished by the scholars of this innovative therapeutic technique. Though the experimental trials have been ongoing from 1990s, however, it took a leap forward with approval of the clinical trials in China, 2005. The world's first oncolytic virus to be approved by their government was adenovirus (with E1B 55K gene deletion) for head and neck cancer therapy along with chemotherapy.
authors.affiliation: Associate Professor Department of Oral Pathology and Microbiology Faculty of Dental Sciences MS Ramaiah University of Applied Sciences Bengaluru, Karnataka, India.
authors.forename: Shankargouda
authors.initials: S
authors.lastname: Patil
authors.affiliation: Professor and Head Department of Oral Pathology and Microbiology Faculty of Dental Sciences MS Ramaiah University of Applied Sciences Bengaluru, Karnataka, India.
authors.forename: Roopa S
authors.initials: RS
authors.lastname: Rao
authors.affiliation: Postgraduate Student Department of Oral Pathology and Microbiology Faculty of Dental Sciences MS Ramaiah University of Applied Sciences Bengaluru, Karnataka, India.
authors.forename: Barnali
authors.initials: B
authors.lastname: Majumdar
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D050130:Oncolytic Virotherapy