title: Administration of Oral Itraconazole Capsule with Whole Milk Shows Enhanced Efficacy As Supported by Scanning Electron Microscopy in a Child with Tinea Capitis Due to Microsporum canis.
abstract: Although diagnosis and treatment of tinea capitis in children are not difficult, treatment failures are still somewhat common. We report a case of pediatric tinea capitis cured using oral itraconazole administered with whole milk, after prior treatment failure when oral itraconazole was administered with water. This apparent enhanced efficacy in one individual was demonstrated using scanning electron microscopy.
authors.affiliation: Department of Dermatovenereology, Sichuan University, Chengdu, China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Chen
authors.affiliation: Department of Dermatovenereology, Sichuan University, Chengdu, China.
authors.forename: Yuping
authors.initials: Y
authors.lastname: Ran
authors.affiliation: Medical Laboratory, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Yalin
authors.initials: Y
authors.lastname: Dai
authors.affiliation: Department of Dermatovenereology, Sichuan University, Chengdu, China.
authors.forename: Jebina
authors.initials: J
authors.lastname: Lama
authors.affiliation: Department of Dermatovenereology, Sichuan University, Chengdu, China.
authors.forename: Wenying
authors.initials: W
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
authors.forename: Chaoliang
authors.initials: C
authors.lastname: Zhang
mesh_terms: D000284:Administration, Oral; D000505:Alopecia / Q000175:diagnosis / Q000209:etiology; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005500:Follow-Up Studies; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage*; D008297:Male; D008855:Microscopy, Electron, Scanning / Q000379:methods; D008864:Microsporum / Q000187:drug effects* / Q000302:isolation & purification; D008892:Milk; D012720:Severity of Illness Index; D014006:Tinea Capitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole