title: Presumed Perinatal Stroke: Risk Factors, Clinical and Radiological Findings.
abstract: It is unknown why some infants with perinatal stroke present clinical symptoms late during infancy and will be identified as infants with presumed perinatal stroke. The risk factors and clinical and radiological data of 42 infants with presumed perinatal stroke (69% with periventricular venous infarction and 31% with arterial ischemic stroke) from the Estonian Pediatric Stroke Database were reviewed. Children with presumed perinatal stroke were born at term in 95% of the cases and had had no risk factors during pregnancy in 43% of the cases. Children with periventricular venous infarction were born significantly more often (82%) vaginally (P = .0213) compared to children with arterial stroke (42%); nor did they require resuscitation (P = .0212) or had any neurological symptoms after birth (P = .0249). Periventricular venous infarction is the most common type of lesion among infants with the presumed perinatal stroke. Data suggest that the disease is of prenatal origin.
authors.affiliation: Radiology Clinic of Tartu University Hospital, Tartu, Estonia Department of Radiology, University of Tartu, Tartu, Estonia pilvi.ilves@kliinikum.ee.
authors.forename: Pilvi
authors.initials: P
authors.lastname: Ilves
authors.affiliation: Department of Pediatrics, University of Tartu, Tartu, Estonia Children's Clinic of Tartu University Hospital, Tartu, Estonia.
authors.forename: Rael
authors.initials: R
authors.lastname: Laugesaar
authors.affiliation: Radiology Clinic of Tartu University Hospital, Tartu, Estonia.
authors.forename: Dagmar
authors.initials: D
authors.lastname: Loorits
authors.affiliation: Department of Pediatrics, University of Tartu, Tartu, Estonia Department of Neurology and Neurorehabilitation, Children's Clinic of Tartu University Hospital, Tartu, Estonia.
authors.forename: Anneli
authors.initials: A
authors.lastname: Kolk
authors.affiliation: Radiology Clinic of Tartu University Hospital, Tartu, Estonia.
authors.forename: Tiiu
authors.initials: T
authors.lastname: Tomberg
authors.affiliation: Department of Pediatrics, University of Tartu, Tartu, Estonia.
authors.forename: Silva
authors.initials: S
authors.lastname: Lõo
authors.affiliation: Department of Pediatrics, University of Tartu, Tartu, Estonia Department of Neurology and Neurorehabilitation, Children's Clinic of Tartu University Hospital, Tartu, Estonia.
authors.forename: Inga
authors.initials: I
authors.lastname: Talvik
authors.affiliation: Department of Genetics, United Laboratories of Tartu University Hospital, Tartu, Estonia.
authors.forename: Tiina
authors.initials: T
authors.lastname: Kahre
authors.affiliation: Department of Pediatrics, University of Tartu, Tartu, Estonia Children's Clinic of Tartu University Hospital, Tartu, Estonia.
authors.forename: Tiina
authors.initials: T
authors.lastname: Talvik
mesh_terms: D016208:Databases, Factual / Q000706:statistics & numerical data; D004957:Estonia / Q000453:epidemiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012307:Risk Factors; D020521:Stroke / Q000000981:diagnostic imaging* / Q000453:epidemiology
keywords: CT; MRI; pediatric stroke; perinatal stroke; presumed perinatal stroke