title: Slowly progressive Lemierre's syndrome with orbital pain and exophthalmos.
abstract: Lemierre's syndrome is an oropharyngeal bacterial infection characterized by rapidly progressive septic thrombophlebitis of the internal jugular vein. A lack of appropriate antibiotic therapy can be life-threatening. We describe the case of a 39-year-old man with Lemierre's syndrome who presented with long-lasting orbital pain and acute exophthalmos 6 weeks after initial infection. This report is to help clinicians consider the diagnosis of Lemierre's syndrome when encountering a patient with long-lasting orbital pain and acute exophthalmos. Neck ultrasonography is useful for detecting thrombophlebitis of the internal jugular vein in Lemierre's syndrome patients.
authors.affiliation: Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Hama
authors.affiliation: Division of Stroke Care Unit, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan. Electronic address: koga@ncvc.go.jp.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Koga
authors.affiliation: Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Fujinami
authors.affiliation: Department of Neurology, Kansai Medical University, Hirakata, Osaka, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Asayama
authors.affiliation: Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Toyoda
mesh_terms: D000328:Adult; D005094:Exophthalmos; D006801:Humans; D007601:Jugular Veins / Q000473:pathology; D057831:Lemierre Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology; D008297:Male; D009915:Orbit / Q000503:physiopathology; D010146:Pain; D013924:Thrombophlebitis / Q000175:diagnosis / Q000209:etiology; D014463:Ultrasonography
keywords: Cerebral venous sinus thrombosis; Exophthalmos; Fusobacterium nucleatum; Lemierre's syndrome; Orbital pain