title: Selective functionalization of mesoporous silica nanoparticles with ibuprofen and Gd(III) chelates: a new probe for potential theranostic applications.
abstract: Organo-modified mesoporous silica nanoparticles, loaded with ibuprofen into the pores and functionalized on the external surface with a stable Gd(iii)-DOTA-monoamide chelate, were prepared and explored as potential theranostic probes.
authors.affiliation: Dipartimento di Scienze e Innovazione Tecnologica, Università degli Studi del Piemonte Orientale "A. Avogadro", V.le Michel 11, I-15121, Alessandria, Italy. mauro.botta@uniupo.it.
authors.forename: Fabio
authors.initials: F
authors.lastname: Carniato
authors.forename: Mónica
authors.initials: M
authors.lastname: Muñoz-Úbeda
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Tei
authors.forename: Mauro
authors.initials: M
authors.lastname: Botta
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000737:chemistry / Q000627:therapeutic use; D002614:Chelating Agents / Q000737:chemistry*; D006573:Heterocyclic Compounds, 1-Ring / Q000737:chemistry; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage* / Q000737:chemistry / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D000068936:Theranostic Nanomedicine
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D002614:Chelating Agents; D006573:Heterocyclic Compounds, 1-Ring; C071349:1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid; D012822:Silicon Dioxide; D007052:Ibuprofen