title: Intradiploic epidermoid cyst with intracranial hypertension syndrome: Report of two cases and literature review.
abstract: BACKGROUND
  Intradiploic epidermoid intracranial cysts (IEIC) derive from ectodermal cells and are covered with stratified squamous epithelium. They are extremely rare, and most common locations are in the occipital, frontal and parietal bones. They have a very slow growth and can be asymptomatic until becoming evident by the deformation produced. The treatment is based on the removal of the lesion, and subsequent histopathological confirmation.
  
  
  METHODS
  Two cases are reported, with intracranial hypertension syndrome, which is very uncommon because of the slow growth of this type of pathology; however, decompensations occurring in the space-occupying lesions at intracranial level explain this type of clinical presentation.
  
  
  CONCLUSIONS
  The most common presentation of intracranial intradiploic epidermoid cysts (IEIC) is asymptomatically, which is made evident by the prominence at the level of the soft tissues and then presenting less frequently local pain and cephalea; rarely the size of the lesion can cause focal neurological signs.
  
  
  CONCLUSIONS
  These benign lesions, although they are of low incidence, are seen very rarely in intradiploic locations and above all, of significant size, may produce significant mass effect in patients, which was initially tolerated because of its slow growth, however, they may become decompensate and cause intracranial hypertension syndrome.
authors.affiliation: Neurosurgery Department, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", Mexico City, Mexico. Electronic address: jcmoreiraholguin@neurocirugia-innn.com.
authors.forename: J C
authors.initials: JC
authors.lastname: Moreira-Holguin
authors.affiliation: Neurosurgery Department, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", Mexico City, Mexico.
authors.forename: R
authors.initials: R
authors.lastname: Medélez-Borbonio
authors.affiliation: Neurosurgery Department, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", Mexico City, Mexico.
authors.forename: E
authors.initials: E
authors.lastname: Quintero-Lopez
authors.affiliation: Neurosurgery Department, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", Mexico City, Mexico.
authors.forename: U
authors.initials: U
authors.lastname: García-González
authors.affiliation: Neurosurgery Department, National Institute of Neurology and Neurosurgery "Manuel Velasco Suárez", Mexico City, Mexico.
authors.forename: J L
authors.initials: JL
authors.lastname: Gómez-Amador
keywords: Extradural cyst; Hypertension syndrome; Intradiploic; Intradiploic epidermoid cyst; Squamous