title: DOT1L: a new therapeutic target for aggressive breast cancer.
authors.affiliation: Department of Pathology, College of Medicine, Hanyang University, Seoul, Republic of Korea.
authors.forename: Jeong-Yeon
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Pathology, College of Medicine, Hanyang University, Seoul, Republic of Korea.
authors.forename: Gu
authors.initials: G
authors.lastname: Kong
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D001562:Benzimidazoles / Q000494:pharmacology; D001943:Breast Neoplasms / Q000188:drug therapy / Q000235:genetics*; D058750:Epithelial-Mesenchymal Transition / Q000235:genetics* / Q000502:physiology; D005260:Female; D011495:Histone-Lysine N-Methyltransferase; D006657:Histones / Q000378:metabolism; D006801:Humans; D007938:Leukemia / Q000188:drug therapy / Q000235:genetics*; D008745:Methylation; D008780:Methyltransferases / Q000037:antagonists & inhibitors / Q000235:genetics* / Q000378:metabolism; D051379:Mice; D014411:Neoplastic Stem Cells; D015533:Transcriptional Activation / Q000235:genetics
chemical_list: D000970:Antineoplastic Agents; D001562:Benzimidazoles; C583893:EPZ-5676; D006657:Histones; C473477:DOT1L protein, human; D008780:Methyltransferases; D011495:Histone-Lysine N-Methyltransferase
keywords: Chromosome Section; DOT1L; EMT; breast cancer; histone methylation