title: Outcome of adenotonsillectomy for children with sleep apnea.
abstract: OBJECTIVE
  The prevalence of obstructive sleep apnea syndrome is about 1%-4.9% in children aged 2-18 years. This is a prospective study carried out to evaluate the role of adenotonsillectomy (AT) in pediatric sleep apnea.
  
  
  METHODS
  Fifty children aged less than 15 years presenting with the chief complaints of snoring, mouth breathing, recurrent upper respiratory infections, and adenotonsillar hypertrophy were included in the study. Physical examination included body mass index (BMI) z-score, orodental and nasal examination, modified Mallampati scoring; whole-night level I polysomnography was conducted and repeated after three to six months of AT.
  
  
  RESULTS
  The mean preoperative BMI z-score was -0.76, which improved significantly to -0.15 (p < 0.001) after AT. A negative correlation was seen between respiratory distress index (RDI) and pre surgery BMI z-score. As per pre-operative RDI, OSA was classified mild in 6.7% children (31.1% as per apnea-hypopnea index [AHI]), moderate in 35.6% (31.1% as per AHI), and severe in 57.8% (37.8% as per AHI). The average RDI value reduced significantly from 16.2 ± 10.7 to 6.46 ± 4.8 (p < 0.001) and AHI from 8.5 (SD ± 5.7) to 1.3 (SD ± 1) post-operatively. Only 6.7% children could be cured with surgery, of whom none belonged to moderate or severe category. Multivariate analysis shows that initial severity of disease, modified Mallampati scores III and IV, high-arched palate, and age above eight years were associated with significant residual disease after AT.
  
  
  CONCLUSIONS
  AT was associated with a statistically significant change in RDI and AHI. However, complete resolution of OSA could be seen in a small percentage of patients with a mild degree of disease.
authors.affiliation: Department of Pulmonary, Critical Care & Sleep Medicine, VMMC & Safdarjang Hospital, New Delhi, India. Electronic address: docjcsuri@gmail.com.
authors.forename: Jagdish Chander
authors.initials: JC
authors.lastname: Suri
authors.affiliation: Department of Pulmonary, Critical Care & Sleep Medicine, VMMC & Safdarjang Hospital, New Delhi, India.
authors.forename: Manas K
authors.initials: MK
authors.lastname: Sen
authors.affiliation: Department of ENT, VMMC & Safdarjang Hospital, New Delhi, India.
authors.forename: V P
authors.initials: VP
authors.lastname: Venkatachalam
authors.affiliation: Department of ENT, VMMC & Safdarjang Hospital, New Delhi, India.
authors.forename: Shikha
authors.initials: S
authors.lastname: Bhool
authors.affiliation: Department of Pulmonary, Critical Care & Sleep Medicine, VMMC & Safdarjang Hospital, New Delhi, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Department of Pulmonary, Critical Care & Sleep Medicine, VMMC & Safdarjang Hospital, New Delhi, India.
authors.forename: Mir
authors.initials: M
authors.lastname: Elias
authors.affiliation: National Institute of Medical Statistics, Indian Council of Medical Research, New Delhi, India.
authors.forename: Tulsi
authors.initials: T
authors.lastname: Adhikari
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000150:complications; D008297:Male; D014066:Palatine Tonsil / Q000473:pathology / Q000601:surgery; D011446:Prospective Studies; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000209:etiology / Q000601:surgery*; D014068:Tonsillectomy; D016896:Treatment Outcome
keywords: Adenotonsillectomy; Pediatric sleep apnea; Polysomnography; Respiratory distress index