title: The Long, the Short, and the Unstructured: A Unifying Model of miRNA Biogenesis.
abstract: In this issue, Fang and Bartel (2015) report the identification of novel sequence and structural features of human pri-miRNAs, which--together with previously identified sequence motifs--define a unifying model of mammalian pri-miRNAs and advances the de novo design of artificial pri-miRNAs.
authors.affiliation: Institute of Molecular Health Sciences, ETH Zurich, Otto-Stern-Weg 7, HPL H36, 8093 Zurich, Switzerland. Electronic address: denzler@biol.ethz.ch.
authors.forename: Rémy
authors.initials: R
authors.lastname: Denzler
authors.affiliation: Institute of Molecular Health Sciences, ETH Zurich, Otto-Stern-Weg 7, HPL H36, 8093 Zurich, Switzerland. Electronic address: stoffel@biol.ethz.ch.
authors.forename: Markus
authors.initials: M
authors.lastname: Stoffel
mesh_terms: D019295:Computational Biology / Q000379:methods*; D006801:Humans; D035683:MicroRNAs / Q000378:metabolism*; D012322:RNA Precursors / Q000737:chemistry*
chemical_list: D035683:MicroRNAs; D012322:RNA Precursors