title: Final 3-Year Outcome of a Randomized Trial Comparing Second-Generation Drug-Eluting Stents Using Either Biodegradable Polymer or Durable Polymer: NOBORI Biolimus-Eluting Versus XIENCE/PROMUS Everolimus-Eluting Stent Trial.
abstract: BACKGROUND
  There is a paucity of data reporting the clinical outcomes of biodegradable polymer biolimus-eluting stent (BP-BES) compared with durable polymer everolimus-eluting stent (DP-EES) beyond 1 year after stent implantation when the polymer is fully degraded.
  
  
  RESULTS
  The NOBORI Biolimus-Eluting Versus XIENCE/PROMUS Everolimus-Eluting Stent Trial (NEXT) is a prospective, multicenter, randomized, open-label, noninferiority trial comparing BP-BES with DP-EES in patients scheduled for percutaneous coronary intervention using drug-eluting stent (DES) without any exclusion criteria among 98 participating centers in Japan. The trial was designed to evaluate noninferiority of BP-BES relative to DP-EES in terms of any target-lesion revascularization at 1 year and death or myocardial infarction at 3 years. Between May and October 2011, 3235 patients were randomly assigned to receive either BP-BES (1617 patients) or DP-EES (1618 patients). Complete 3-year follow-up was achieved in 97.6% of patients. At 3 years, the primary safety end point of death or myocardial infarction occurred in 159 patients (9.9%) in the BP-BES group and in 166 patients (10.3%) in the DP-EES group, demonstrating noninferiority of BP-BES relative to DP-EES (P noninferiority<0.0001 and P superiority=0.7). Cumulative incidence of target-lesion revascularization was not significantly different between the 2 groups (7.4% versus 7.1%; P=0.8). By a landmark analysis at 1 year, the cumulative incidences of death or myocardial infarction and target-lesion revascularization were also not significantly different between the 2 groups (4.6% versus 5.2%; P=0.46 and 3.3% versus 2.7%; P=0.39, respectively).
  
  
  CONCLUSIONS
  Safety and efficacy outcomes of BP-BES were non inferior to those of DP-EES 3 years after stent implantation.
  
  
  BACKGROUND
  URL: http://www.clinicaltrials.gov. Unique identifier: NCT01303640.
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Masahiro
authors.initials: M
authors.lastname: Natsuaki
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Ken
authors.initials: K
authors.lastname: Kozuma
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Takeshi
authors.initials: T
authors.lastname: Morimoto
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Kazushige
authors.initials: K
authors.lastname: Kadota
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Toshiya
authors.initials: T
authors.lastname: Muramatsu
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Nakagawa
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Takashi
authors.initials: T
authors.lastname: Akasaka
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Keiichi
authors.initials: K
authors.lastname: Igarashi
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Kengo
authors.initials: K
authors.lastname: Tanabe
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Morino
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Ishikawa
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Hideo
authors.initials: H
authors.lastname: Nishikawa
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Masaki
authors.initials: M
authors.lastname: Awata
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Abe
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Hisayuki
authors.initials: H
authors.lastname: Okada
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Takatsu
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Ogata
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kimura
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Kazushi
authors.initials: K
authors.lastname: Urasawa
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Tarutani
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.).
authors.forename: Nobuo
authors.initials: N
authors.lastname: Shiode
authors.affiliation: Division of Cardiology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan (M.N.); Division of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma); Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T. Morimoto); Department of Cardiology, Kurashiki Central Hospital, Kurashiki, Japan (K. Kadota); Division of Cardiology, Saiseikai Yokohama-city Eastern Hospital, Yokohama, Japan (T. Muramatsu); Division of Cardiology, Tenri Hospital, Tenri, Japan (Y.N.); Department of Cardiovascular Medicine, Wakayama Medical University Hospital, Wakayama, Japan (T.A.); Division of Cardiology, Japan Community Health Care Organization Hokkaido Social Hospital, Sapporo, Japan (K.I.); Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K.T.); Division of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.); Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kumagaya, Japan (T.I.); Division of Cardiology, Mie Heart Center, Mie, Japan (H.N.); Division of Cardiology, Kansai Rosai Hospital Cardiovascular Center, Amagasaki, Japan (M. Awata); Division of Cardiology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan (M. Abe); Division of Cardiology, Seirei Hamamatsu General Hospital, Hamamatsu, Japan (H.O.); Division of Cardiology, Hyogo Prefectural Amagasaki Hospital, Amagasaki, Japan (Y. Takatsu); Division of Cardiology, Jichi Medical University Hospital, Shimotsuke, Japan (N.O.); Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan (K. Kimura); Division of Cardiology, Caress Sapporo Tokeidai Memorial Hospital, Sapporo, Japan (K.U.); Division of Cardiology, Okamura Memorial Hospital, Shizuoka, Japan (Y. Tarutani); Division of Cardiology, Tsuchiya General Hospital, Hiroshima, Japan (N.S.); and Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan (T.K.). taketaka@kuhp.kyoto-u.ac.jp.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kimura
mesh_terms: D020341:Absorbable Implants / Q000706:statistics & numerical data; D000368:Aged; D019917:Blood Vessel Prosthesis Implantation; D054855:Drug-Eluting Stents / Q000706:statistics & numerical data*; D000068338:Everolimus / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology* / Q000401:mortality; D062645:Percutaneous Coronary Intervention; D011183:Postoperative Complications / Q000401:mortality; D011446:Prospective Studies; D020123:Sirolimus / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D000068338:Everolimus; C518022:umirolimus; D020123:Sirolimus
keywords: coronary artery disease; drug-eluting stents; percutaneous coronary intervention; stents