title: Lysosomal mTORC2/PHLPP1/Akt axis: a new point of control of chaperone-mediated autophagy.
authors.affiliation: Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY, USA.
authors.forename: Esperanza
authors.initials: E
authors.lastname: Arias
mesh_terms: D000818:Animals; D001343:Autophagy / Q000502:physiology; D006801:Humans; D000076225:Mechanistic Target of Rapamycin Complex 2; D051379:Mice; D018832:Molecular Chaperones / Q000378:metabolism*; D046912:Multiprotein Complexes / Q000378:metabolism*; D009687:Nuclear Proteins / Q000378:metabolism*; D010749:Phosphoprotein Phosphatases / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*; D058570:TOR Serine-Threonine Kinases / Q000378:metabolism*
chemical_list: D018832:Molecular Chaperones; D046912:Multiprotein Complexes; D009687:Nuclear Proteins; D000076225:Mechanistic Target of Rapamycin Complex 2; D051057:Proto-Oncogene Proteins c-akt; D058570:TOR Serine-Threonine Kinases; C400601:PHLPP1 protein, human; C519282:PHLPP1 protein, mouse; D010749:Phosphoprotein Phosphatases
keywords: cell signaling; kinase; lysosomes; membrane proteins; phosphatase