title: Microsphaeropsis arundinis skin and soft tissue infection in renal transplant recipients: three case reports and a review of the literature.
abstract: Microsphaeropsis arundinis, a dematiaceous mold, is emerging as a cause of skin and soft tissue infection in immunocompromised hosts. Diagnosis is challenging because of the difficulty in identifying Microsphaeropsis species morphologically and few data are available to guide optimal management. We report 3 renal transplant recipients with M. arundinis soft tissue infection, where the etiological agent was diagnosed using DNA sequencing, and who were successfully treated with prolonged courses of extended-spectrum triazole antifungal agents.
authors.affiliation: Infectious Diseases Department, Wollongong Hospital, Wollongong, New South Wales, Australia.
authors.forename: S J
authors.initials: SJ
authors.lastname: Crawford
authors.affiliation: Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research - Pathology West, Westmead Hospital, Westmead, New South Wales, Australia.|Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: S C-A
authors.initials: SC
authors.lastname: Chen
authors.affiliation: Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research - Pathology West, Westmead Hospital, Westmead, New South Wales, Australia.|Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: C
authors.initials: C
authors.lastname: Halliday
authors.affiliation: Department of Renal Medicine, Westmead Hospital, Westmead, New South Wales, Australia.|Centre for Transplant and Renal Research, Westmead Millennium Institute for Medical Research, University of Sydney, Westmead, New South Wales, Australia.
authors.forename: G K
authors.initials: GK
authors.lastname: Rangan
authors.affiliation: Department of Infectious Diseases and Microbiology, Concord Hospital, Concord, New South Wales, Australia.|Concord Clinical School, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: T
authors.initials: T
authors.lastname: Gottlieb
authors.affiliation: Infectious Diseases Department, Wollongong Hospital, Wollongong, New South Wales, Australia.|Graduate School of Medicine, University of Wollongong, Wollongong, New South Wales, Australia.
authors.forename: A B
authors.initials: AB
authors.lastname: Reid
mesh_terms: D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D018461:Soft Tissue Infections / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology
chemical_list: D000935:Antifungal Agents
keywords: Microsphaeropsis arundinis; fungi; immunocompromised host; molecular typing; opportunistic infection; phaeohyphomycosis; renal transplantation; skin diseases, infectious; soft tissue infections