title: Magnetic resonance imaging findings of two sisters with Van der Knaap leukoencephalopathy.
abstract: Megalencephalic leukoencephalopathy with subcortical cysts, or Van der Knaap leukoencephalopathy, is a rare disease which is characterised by macrocephaly and neurological disorders with autosomal recessive inheritance. Magnetic resonance imaging is very helpful for determining distinctive findings and distinguishing other diseases. We present the radiological findings of two sisters (aged 6 and 10 years) diagnosed with Van der Knaap leukoencephalopathy.
authors.affiliation: Antalya Ataturk State Hospital, Radiology Clinics, Antalya, Turkey koraykoc@yahoo.com.
authors.forename: Koray
authors.initials: K
authors.lastname: Koç
authors.affiliation: Antalya Training and Research Hospital, Radiology Clinics, Antalya, Turkey.
authors.forename: Pınar
authors.initials: P
authors.lastname: Koç
authors.affiliation: Akdeniz University, School of Medicine, Department of Radiology, Antalya, Turkey.
authors.forename: Kamil
authors.initials: K
authors.lastname: Karaali
authors.affiliation: Akdeniz University, School of Medicine, Department of Pediatry, Antalya, Turkey.
authors.forename: Nihal
authors.initials: N
authors.lastname: Olgaç Dündar
authors.affiliation: Akdeniz University, School of Medicine, Department of Radiology, Antalya, Turkey.
authors.forename: Utku
authors.initials: U
authors.lastname: Şenol
authors.affiliation: Antalya Ataturk State Hospital, Radiology Clinics, Antalya, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Canan
mesh_terms: D002648:Child; D003241:Consanguinity; D003560:Cysts / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D020279:Hereditary Central Nervous System Demyelinating Diseases / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D035781:Siblings
keywords: Leukoencephalopathy; Van der Knaap disease; magnetic resonance imaging