title: Safety and efficacy of wavefront-guided myopic laser in situ keratomileusis using a new wavefront sensor technology: first 100 cases.
abstract: OBJECTIVE
  To evaluate the safety and efficacy of wavefront-guided laser in situ keratomileusis (LASIK) for the correction of low to high myopia and myopic astigmatism using data derived from a new-generation Hartmann-Shack aberrometer.
  
  
  METHODS
  Refractive Surgery Unit, Bordeaux Hospital University, France.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  This retrospective study analyzed the initial group of eyes treated with wavefront-guided LASIK for myopia and myopic astigmatism using the Visx S4IR excimer laser and wavefront data derived from a new Hartmann-Shack aberrometer (iDesign Advanced Wavescan aberrometer). Refractive (refraction and refractive accuracy) and visual outcomes (uncorrected [UDVA] and corrected [CDVA] distance visual acuities) were recorded 3 months postoperatively.
  
  
  RESULTS
  The study included 100 eyes of 50 consecutively treated patients. The mean decimal UDVA improved from 0.1 ± 0.1 (SD) preoperatively to 1.1 ± 0.15 postoperatively (P < .01). A monocular UDVA of 20/16, 20/20, and 20/25 were achieved in 76.6%, 94.4%, and 96.6% of eyes, respectively. The postoperative manifest spherical equivalent was within ±0.5 diopter in all eyes. No eye lost 2 or more lines of CDVA, and 29.2% of the eyes gained 1 or more lines of CDVA.
  
  
  CONCLUSIONS
  Wavefront-guided LASIK performed using data derived from the new Hartmann-Shack aberrometer was safe, effective, and predictable for treating myopia and myopic astigmatism.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the Ophthalmology Department, Tel Aviv Sourasky Medical Center (Smadja), and the Institute of Nanotechnology and Advanced Materials (Smadja), Bar-Ilan University, Tel Aviv, Israel; the National Reference Center for Keratoconus (Smadja, Tellouck, De Castro, Lecomte, Touboul), Bordeaux Hospital University, Bordeaux, France; Department of Ophthalmology (Santhiago), Federal University of Rio De Janeiro, Rio, Brazil, Department Of Ophthalmology (Mello), Federal University Of Paraná, Curitiba, Brazil. Electronic address: davidsmadj@hotmail.fr.
authors.forename: David
authors.initials: D
authors.lastname: Smadja
authors.affiliation: From the Ophthalmology Department, Tel Aviv Sourasky Medical Center (Smadja), and the Institute of Nanotechnology and Advanced Materials (Smadja), Bar-Ilan University, Tel Aviv, Israel; the National Reference Center for Keratoconus (Smadja, Tellouck, De Castro, Lecomte, Touboul), Bordeaux Hospital University, Bordeaux, France; Department of Ophthalmology (Santhiago), Federal University of Rio De Janeiro, Rio, Brazil, Department Of Ophthalmology (Mello), Federal University Of Paraná, Curitiba, Brazil.
authors.forename: Marcony R
authors.initials: MR
authors.lastname: Santhiago
authors.affiliation: From the Ophthalmology Department, Tel Aviv Sourasky Medical Center (Smadja), and the Institute of Nanotechnology and Advanced Materials (Smadja), Bar-Ilan University, Tel Aviv, Israel; the National Reference Center for Keratoconus (Smadja, Tellouck, De Castro, Lecomte, Touboul), Bordeaux Hospital University, Bordeaux, France; Department of Ophthalmology (Santhiago), Federal University of Rio De Janeiro, Rio, Brazil, Department Of Ophthalmology (Mello), Federal University Of Paraná, Curitiba, Brazil.
authors.forename: Joy
authors.initials: J
authors.lastname: Tellouck
authors.affiliation: From the Ophthalmology Department, Tel Aviv Sourasky Medical Center (Smadja), and the Institute of Nanotechnology and Advanced Materials (Smadja), Bar-Ilan University, Tel Aviv, Israel; the National Reference Center for Keratoconus (Smadja, Tellouck, De Castro, Lecomte, Touboul), Bordeaux Hospital University, Bordeaux, France; Department of Ophthalmology (Santhiago), Federal University of Rio De Janeiro, Rio, Brazil, Department Of Ophthalmology (Mello), Federal University Of Paraná, Curitiba, Brazil.
authors.forename: Tania
authors.initials: T
authors.lastname: De Castro
authors.affiliation: From the Ophthalmology Department, Tel Aviv Sourasky Medical Center (Smadja), and the Institute of Nanotechnology and Advanced Materials (Smadja), Bar-Ilan University, Tel Aviv, Israel; the National Reference Center for Keratoconus (Smadja, Tellouck, De Castro, Lecomte, Touboul), Bordeaux Hospital University, Bordeaux, France; Department of Ophthalmology (Santhiago), Federal University of Rio De Janeiro, Rio, Brazil, Department Of Ophthalmology (Mello), Federal University Of Paraná, Curitiba, Brazil.
authors.forename: Fanny
authors.initials: F
authors.lastname: Lecomte
authors.affiliation: From the Ophthalmology Department, Tel Aviv Sourasky Medical Center (Smadja), and the Institute of Nanotechnology and Advanced Materials (Smadja), Bar-Ilan University, Tel Aviv, Israel; the National Reference Center for Keratoconus (Smadja, Tellouck, De Castro, Lecomte, Touboul), Bordeaux Hospital University, Bordeaux, France; Department of Ophthalmology (Santhiago), Federal University of Rio De Janeiro, Rio, Brazil, Department Of Ophthalmology (Mello), Federal University Of Paraná, Curitiba, Brazil.
authors.forename: Glauco R
authors.initials: GR
authors.lastname: Mello
authors.affiliation: From the Ophthalmology Department, Tel Aviv Sourasky Medical Center (Smadja), and the Institute of Nanotechnology and Advanced Materials (Smadja), Bar-Ilan University, Tel Aviv, Israel; the National Reference Center for Keratoconus (Smadja, Tellouck, De Castro, Lecomte, Touboul), Bordeaux Hospital University, Bordeaux, France; Department of Ophthalmology (Santhiago), Federal University of Rio De Janeiro, Rio, Brazil, Department Of Ophthalmology (Mello), Federal University Of Paraná, Curitiba, Brazil.
authors.forename: David
authors.initials: D
authors.lastname: Touboul
mesh_terms: D057128:Aberrometry / Q000379:methods*; D000328:Adult; D003319:Corneal Stroma / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D012029:Refraction, Ocular / Q000502:physiology; D012189:Retrospective Studies; D013524:Surgical Flaps; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult