title: Asymmetric and Diffuse Uptake of Left Femur in a 3-Year-Old Child Bone Scan: An Unusual Aspect in Acute Lymphoblastic Leukemia.
abstract: Acute leukemia is a severe disease frequently encountered in childhood, often diagnosed in later stages because of nonspecific symptoms. It is known to produce uptake in bone scan, and previously described patterns have shown symmetrical abnormalities. However, we report the unusual aspect of the bone scan in a 3-year-old child who was referred to explore an isolated pain of his lower left limb, with hyperthermia and markers of inflammation. A bone scan showed an intense, asymmetrical uptake of the entire left femur. A few days later, his blood count showed circulating blast cells, leading to the diagnosis of leukemia.
authors.affiliation: From the Departments of *Nuclear Medicine, †Radiology, and ‡Paediatric Orthopaedic Surgery, C.H.U de Besancon, 25 000 Besancon, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Morel
authors.forename: Constantin
authors.initials: C
authors.lastname: Ungureanu
authors.forename: Pierre
authors.initials: P
authors.lastname: Padoin
authors.forename: Romain
authors.initials: R
authors.lastname: Laurent
authors.forename: Hatem
authors.initials: H
authors.lastname: Boulahdour
mesh_terms: D002675:Child, Preschool; D005269:Femur / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals