title: Coincidence of late-onset cytomegalovirus-induced myositis and gastritis in a pediatric renal transplant recipient.
abstract: An 8-year-old girl with a renal transplant was admitted for myalgia and muscle weakness in both legs over the previous 2 weeks. She also had fever and intermittent epigastric pain. Based on these clinical manifestations, and laboratory and histopathological findings, the diagnosis was coincidence of late-onset cytomegalovirus (CMV)-induced myositis and gastritis in an immunocompromised child with a renal transplant. After administration of intravenous ganciclovir for 3 weeks, her symptoms resolved, with normalization of abnormal muscle enzymes, including lactate dehydrogenase, creatine kinase, aspartate aminotransferase, and the disappearance of CMV viremia.
authors.affiliation: Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.
authors.forename: H S
authors.initials: HS
authors.lastname: Baek
authors.affiliation: Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.
authors.forename: B H
authors.initials: BH
authors.lastname: Choe
authors.affiliation: Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.
authors.forename: H-K
authors.initials: HK
authors.lastname: Kim
authors.affiliation: Department of Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.
authors.forename: S
authors.initials: S
authors.lastname: Huh
authors.affiliation: Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.
authors.forename: M H
authors.initials: MH
authors.lastname: Cho
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use*; D005756:Gastritis / Q000209:etiology*; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000494:pharmacology; D016030:Kidney Transplantation / Q000009:adverse effects*; D009220:Myositis / Q000209:etiology*; D014766:Viremia / Q000097:blood / Q000188:drug therapy
chemical_list: D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D015774:Ganciclovir
keywords: child; cytomegalovirus; gastritis; myositis; renal transplantation