title: Fracture Rates and Lifetime Estimations of CAD/CAM All-ceramic Restorations.
abstract: The gathering of clinical data on fractures of dental restorations through prospective clinical trials is a labor- and time-consuming enterprise. Here, we propose an unconventional approach for collecting large datasets, from which clinical information on indirect restorations can be retrospectively analyzed. The authors accessed the database of an industry-scale machining center in Germany and obtained information on 34,911 computer-aided design (CAD)/computer-aided manufacturing (CAM) all-ceramic posterior restorations. The fractures of bridges, crowns, onlays, and inlays fabricated from different all-ceramic systems over a period of 3.5 y were reported by dentists and entered in the database. Survival analyses and estimations of future life revealed differences in performance among ZrO2-based restorations and lithium disilicate and leucite-reinforced glass-ceramics.
authors.affiliation: Research Laboratory for Dental Biomaterials, Dental Clinic 1-Operative Dentistry and Periodontology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany rbelli@dent.uni-erlangen.de.
authors.forename: R
authors.initials: R
authors.lastname: Belli
authors.affiliation: Research Laboratory for Dental Biomaterials, Dental Clinic 1-Operative Dentistry and Periodontology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Petschelt
authors.affiliation: Department of Medical Informatics, Biometry and Epidemiology, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Hofner
authors.affiliation: Clinical Practice, Munich, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Hajtó
authors.affiliation: Division of Fixed Prosthodontics-Biomaterials, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.
authors.forename: S S
authors.initials: SS
authors.lastname: Scherrer
authors.affiliation: Research Laboratory for Dental Biomaterials, Dental Clinic 1-Operative Dentistry and Periodontology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Lohbauer
mesh_terms: D000538:Aluminum Silicates / Q000737:chemistry; D002516:Ceramics / Q000737:chemistry*; D017076:Computer-Aided Design; D003442:Crowns; D019992:Databases as Topic; D003764:Dental Materials / Q000737:chemistry*; D003776:Dental Porcelain / Q000737:chemistry; D019232:Dental Restoration Failure; D003793:Dental Restoration, Permanent; D003801:Dental Veneers; D003829:Denture, Partial; D005500:Follow-Up Studies; D006801:Humans; D007284:Inlays; D008422:Materials Testing; D012189:Retrospective Studies; D016019:Survival Analysis; D015040:Zirconium / Q000737:chemistry
chemical_list: D000538:Aluminum Silicates; D003764:Dental Materials; C520133:IPS e.max CAD LT; C075815:IPS-Empress ceramic; C493120:lithia disilicate; D003776:Dental Porcelain; C078519:leucite; C023506:Glass ceramics; D015040:Zirconium; C028541:zirconium oxide
keywords: ceramics; clinical; database; dental; dental restoration failure; retrospective