title: Tissue Engineering: Step Ahead in Maxillofacial Reconstruction.
abstract: Within the precedent decade, a new field of "tissue engineering" or "tissue regeneration" emerge that offers an innovative and exhilarating substitute for maxillofacial reconstruction. It offers a new option to supplement existing treatment regimens for reconstruction/regeneration of the oral and craniofacial complex, which includes the teeth, periodontium, bones, soft tissues (oral mucosa, conjunctiva, skin), salivary glands, and the temporomandibular joint (bone and cartilage), as well as blood vessels, muscles, tendons, and nerves. Tissue engineering is based on harvesting the stem cells which are having potential to form an organ. Harvested cells are then transferred into scaffolds that are manufactured in a laboratory to resemble the structure of the desired tissue to be replaced. This article reviews the principles of tissue engineering and its various applications in oral and maxillofacial surgery.
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, DR. G.D. Pols Foundation YMT Dental College and Hospital, Kharghar, Navi Mumbai, Maharashtra, India.
authors.forename: Raj
authors.initials: R
authors.lastname: Rai
authors.affiliation: Post Graduate Student, Department of Oral and Maxillofacial Surgery, Maharaja Ganga Singh Dental College and Research Centre, Sriaganganagar, Rajasthan, India.
authors.forename: Rushik
authors.initials: R
authors.lastname: Raval
authors.affiliation: Private Practionor, Department of Oral and Maxillofacial Surgery, Goa, India.
authors.forename: Rakshit Vijay Sinai
authors.initials: RV
authors.lastname: Khandeparker
authors.affiliation: Reader, Department of Oral and Maxillofacial Surgery, Rama Dental College Kanpur, Uttar Pradesh, India.
authors.forename: Swati K
authors.initials: SK
authors.lastname: Chidrawar
authors.affiliation: Assistant Professor, Department of Oral and Maxillofacial Surgery, Goverment Dental College and Hospital, Aurangabad, Maharashtra, India.
authors.forename: Abdul Ahad
authors.initials: AA
authors.lastname: Khan
authors.affiliation: Assistant Professor, Department of Pedodontics and Preventive Dentistry, Goverment Dental College and Hospital, Aurangabad, Maharashtra, India.
authors.forename: Makne Sachin
authors.initials: MS
authors.lastname: Ganpat
keywords: Reconstruction; Scaffolds; regeneration; signaling molecules; stem cells; tissue engineering