title: Histological Regression of Giant Cell Tumor of Bone Following RANK Ligand Inhibition.
abstract: Lung metastases are a rare complication of giant cell tumors of bone. We herein describe an interesting case of histological regression and size reduction of lung metastases originating from a primary giant cell tumor of bone in response to the RANK ligand inhibitor denosumab.
authors.affiliation: University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Martin F
authors.initials: MF
authors.lastname: Dietrich
authors.affiliation: University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Dominick
authors.initials: D
authors.lastname: Cavuoti
authors.affiliation: University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Landay
authors.affiliation: University of Texas Southwestern Medical Center, Dallas, TX, USA.
authors.forename: Yull E
authors.initials: YE
authors.lastname: Arriaga
keywords: Giant cell tumor; RANK ligand; denosumab; lung metastases