title: Solid pancreatic lesions: The choice of fine-needle aspiration-needle to optimize the diagnosis.
abstract: BACKGROUND
  Endoscopic ultrasonography (EUS)-guided fine-needle aspiration (FNA) have a better accuracy for the detection of pancreatic tumors compared with others images modalities. We assessed if the image criteria of elastography and contrast harmonic echo-endoscopic ultrasound could help in choosing the appropriate FNA-needle in the evaluation of focal pancreatic mass in other to maximize the diagnostic yield. This study prospectively included all new patients with focal pancreatic masses referred to be examined by EUS from October to December/2013. A total of 21 patients performed EUS with sequentially elastography and intravenous injection of a second-generation contrast agent (2.4 mL of SonoVue, Braco International, The Netherlands). The lesions which appear hipovascular were assessed with 22 gauge or 25 gauge FNA-needles. The hipervascular masses were biopsied with 19 gauge needles.
  
  
  RESULTS
  The topography of the lesions varied on 13 at the head, 4 at the body and 1 on the tail. The finding of a hypoenhanced mass was found in 57% (12/21 patients). Hyperenhanced was detected in 28% (6/21 patients). There were 14% (three patients) which the data were not recorded. The cytological diagnosis was achieved in 81% (17/21 patients) on the first biopsy. The others four patients have reached the diagnosis on the second examination. Of those four patients, in one was used the ProCore 25 gauge (lesion on the uncinatus process), and another one was used both 22 gauge and 25 gauge in the first examination.
  
  
  CONCLUSIONS
  A characterization of the pancreatic lesions with elastography and contrast agents might be useful for clinical decision of which needle is better to improve biopsy quality and minimize EUS-FNA negatives results.
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: E
authors.initials: E
authors.lastname: Francioni
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: S
authors.initials: S
authors.lastname: Reimão
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: E
authors.initials: E
authors.lastname: Bories
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: F
authors.initials: F
authors.lastname: Caillol
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: C
authors.initials: C
authors.lastname: Pesenti
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: F
authors.initials: F
authors.lastname: Poizat
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: G
authors.initials: G
authors.lastname: Monges
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: M
authors.initials: M
authors.lastname: Giovannini