title: Temporal Epidemiological Assessment of Colorectal Cancer Incidence and Mortality in East Kazakhstan, 2004-2013.
abstract: Colorectal cancer incidence and mortality in Kazakhstan are relatively high but exact statistics have hitherto been lacking and trends over time are unclear. The present study was therefore undertaken to retrospectively assess data for East Kazakhstan, accessed from the central registration office, for the period 2004-2013. Approximate age standardized data for incidence and mortality were generated and compared across age groups, gender and year. It was determined that during the studied period 3,417 new cases of colorectal cancer were registered and 2,259 died of this pathology. Average cancer cancer incidence and mortality over the ten years were 24.1/105 and 15.9/105 respectively, and the overall ratio of mortality/incidence (M/I) was 0.69:1 (range 0.58-0.73). Both incidence and mortality tended to remain constant in both males and females. The male to female ratios also did not significantly vary over time but a trend for improvement of the mortality to incidence ratio was observed, especially for rectum. Whether this might be related to screening remains unclear. These preliminary data indicate that whereas colorectal cancer continues to be important, change in environmental factors are not having a great impact on incidence in East Kazakhstan.
authors.affiliation: Semey State Medical University, Semey, Kazakhstan E-mail: n.igissinov@gmail.com.
authors.forename: Kuantkan
authors.initials: K
authors.lastname: Zhabagin
authors.forename: Nurbek
authors.initials: N
authors.lastname: Igissinov
authors.forename: Zukhra
authors.initials: Z
authors.lastname: Manambayeva
authors.forename: Tasbolat
authors.initials: T
authors.lastname: Adylkhanov
authors.forename: Marat
authors.initials: M
authors.lastname: Sandybayev
authors.forename: Murat
authors.initials: M
authors.lastname: Nurgazin
authors.forename: Adilzhan
authors.initials: A
authors.lastname: Massadykov
authors.forename: Sayat
authors.initials: S
authors.lastname: Tanatarov
authors.forename: Daniyar
authors.initials: D
authors.lastname: Aldyngurov
authors.forename: Nailya
authors.initials: N
authors.lastname: Urazalina
authors.forename: Aizhan
authors.initials: A
authors.lastname: Abiltayeva
authors.forename: Ainoor
authors.initials: A
authors.lastname: Baissalbayeva
authors.forename: Almagul
authors.initials: A
authors.lastname: Zhabagina
authors.forename: Dinara
authors.initials: D
authors.lastname: Sabitova
authors.forename: Nurgul
authors.initials: N
authors.lastname: Zhumykbayeva
authors.forename: Dinara
authors.initials: D
authors.lastname: Kenbayeva
authors.forename: Alexander
authors.initials: A
authors.lastname: Rakhimbekov
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D003110:Colonic Neoplasms / Q000453:epidemiology* / Q000401:mortality; D006801:Humans; D015994:Incidence; D007623:Kazakhstan / Q000453:epidemiology; D008875:Middle Aged; D009026:Mortality / Q000639:trends; D012004:Rectal Neoplasms / Q000453:epidemiology* / Q000401:mortality; D012189:Retrospective Studies; D012737:Sex Factors