title: Genetic variations of body weight and GCRV resistance in a random mating population of grass carp.
abstract: The grass carp (Ctenopharyngodon idellus) is an important species in freshwater aquaculture both in China and on a global scale. Variety degeneration and frequent diseases have limited the further development of grass carp aquaculture. Thus, new and improved varieties are required. Here, we identified and assessed the body weight and disease resistance in a random mating population of 19 â × 22 â grass carp, which were derived from different water systems. In both the growth experimental group of 10,245 fish and grass carp reovirus (GCRV)-infected group with 10,000 fish, 78 full-sib families were statistically analyzed for body weight and GCRV resistance. The findings showed that body weight traits had low heritability (0.11 ± 0.04, 0.10 ± 0.03 and 0.12 ± 0.05), GCRV resistance traits had high heritability (0.63 ± 0.11); body weight was higher in 3 families, whereas GCRV resistance was significantly greater in 11 families. Our results confirmed that the natural germplasm resources of wild grass carp were genetically diverse. Breeding of GCRV resistant varieties of grass carp have better genetic basis. This study provides the basis for constructing basal populations for grass carp selective breeding, quantitative trait loci (QTL) and genome-wide association studies (GWAS) analysis.
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Huang
authors.affiliation: Tongwei Company, Limited, Chengdu, China.
authors.forename: Jiaxian
authors.initials: J
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Luo
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
authors.forename: Libo
authors.initials: L
authors.lastname: He
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
authors.forename: Lanjie
authors.initials: L
authors.lastname: Liao
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
authors.forename: Yongming
authors.initials: Y
authors.lastname: Li
authors.affiliation: Tongwei Company, Limited, Chengdu, China.
authors.forename: Fuhua
authors.initials: F
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
authors.forename: Zuoyan
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000818:Animals; D001835:Body Weight; D002347:Carps / Q000235:genetics* / Q000276:immunology / Q000821:virology*; D005260:Female; D005393:Fish Diseases / Q000235:genetics* / Q000276:immunology / Q000821:virology*; D029941:Fish Proteins / Q000235:genetics / Q000276:immunology; D020022:Genetic Predisposition to Disease; D008297:Male; D012087:Reoviridae; D012088:Reoviridae Infections / Q000235:genetics / Q000276:immunology / Q000662:veterinary*
chemical_list: D029941:Fish Proteins
keywords: Ctenopharyngodon idellus; Pathology Section; breeding; full-sib families; paternity test