title: HLA-frequencies of Austrian umbilical cord blood samples.
abstract: We investigated HLA-A, HLA-B, and HLA-DRB1 gene frequencies in 1368 unrelated Austrian umbilical cord blood samples. HLA-C gene frequencies were investigated in a subgroup of 503 samples. HLA typing was performed via sequenced-based typing (SBT). The aim of this study was to examine the HLA diversity in a large Austrian population sample. In addition we present results of a subsample of 100 samples at a subtype level. This study is the first systematic investigation of donated umbilical cord blood samples in the Austrian population.
authors.affiliation: Vivocell Biosolutions, Graz, Austria.
authors.forename: S
authors.initials: S
authors.lastname: Nerstheimer
authors.affiliation: Vivocell Biosolutions, Graz, Austria.
authors.forename: P
authors.initials: P
authors.lastname: Tauscher
authors.affiliation: Institute of Human Genetics, Medical University of Graz, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Petek
authors.affiliation: Department for Mathematics and Scientific Computing, Karl-Franzens-University Graz, Austria. Electronic address: gudrun.schappacher-tilp@uni-graz.at.
authors.forename: G
authors.initials: G
authors.lastname: Schappacher-Tilp
mesh_terms: D000483:Alleles; D001317:Austria; D005312:Fetal Blood / Q000166:cytology; D005787:Gene Frequency; D008040:Genetic Linkage; D005828:Genetics, Population; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens / Q000235:genetics; D015235:HLA-B Antigens / Q000235:genetics; D015236:HLA-C Antigens / Q000235:genetics; D059811:HLA-DRB1 Chains / Q000235:genetics; D006239:Haplotypes; D006650:Histocompatibility Testing; D006801:Humans; D015810:Linkage Disequilibrium
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D059811:HLA-DRB1 Chains
keywords: Austrian population; HLA; Haplotype and allele frequencies; High-resolution typing; Umbilical cord blood