title: Generation of iPSC line MU011.A-hiPS from homozygous α-thalassemia fetal skin fibroblasts.
abstract: Human iPSC line MU011.A-hiPS was generated from homozygous α-thalassemia (-(SEA)/-(SEA)) fetal skin fibroblasts using a non-integrative reprogramming method. Reprogramming factors OCT3/4, SOX2, KLF4, L-MYC, LIN28, and shRNA of TP53 contained in three episomal vectors were delivered using electroporation.
authors.affiliation: Office of Research, Academic Affairs and Innovations, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Amornrat
authors.initials: A
authors.lastname: Tangprasittipap
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Chonthicha
authors.initials: C
authors.lastname: Satirapod
authors.affiliation: Office of Research, Academic Affairs and Innovations, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Bunyada
authors.initials: B
authors.lastname: Jittorntrum
authors.affiliation: Office of Research, Academic Affairs and Innovations, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Sassawat
authors.initials: S
authors.lastname: Lertritanan
authors.affiliation: Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Usanarat
authors.initials: U
authors.lastname: Anurathaphan
authors.affiliation: Department of Anatomy, Faculty of Science, Mahidol University, Bangkok, Thailand; Stem Cell Research Group, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand.
authors.forename: Phetcharat
authors.initials: P
authors.lastname: Phanthong
authors.affiliation: Department of Biotechnology, Faculty of Science, Mahidol University, Bangkok, Thailand.
authors.forename: Suparerk
authors.initials: S
authors.lastname: Borwornpinyo
authors.affiliation: Stem Cell Research Group, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand. Electronic address: narisorn.kit@mahidol.ac.th.
authors.forename: Narisorn
authors.initials: N
authors.lastname: Kitiyanant
authors.affiliation: Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Electronic address: suradej.hon@mahidol.ac.th.
authors.forename: Suradej
authors.initials: S
authors.lastname: Hongeng
mesh_terms: D002460:Cell Line; D005333:Fetus / Q000166:cytology / Q000378:metabolism*; D005347:Fibroblasts / Q000378:metabolism*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000378:metabolism*; D000090062:Kruppel-Like Factor 4; D012867:Skin / Q000166:cytology / Q000378:metabolism*; D017085:alpha-Thalassemia / Q000235:genetics*