title: Isolated Atrial Septal Defect Complicated by Tricuspid Valve Infective Endocarditis.
abstract: Infective endocarditis (IE) associated with atrial septal defect (ASD) is extremely rare. However, tricuspid regurgitation (TR) secondary to right ventricular overload is a potential cause of IE, and once it occurs, the development of a paradoxical embolism may lead to fatal complications. We herein report the case of a 50-year-old woman who was admitted due to a persistent fever resistant to antibiotics. Echocardiography showed secundum ASD, moderate TR and a mobile vegetation measuring 15×10 mm attached to the tricuspid valve. Given the risk of developing a paradoxical embolism, urgent surgery was successfully performed.
authors.affiliation: Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, Japan.
authors.forename: Mai
authors.initials: M
authors.lastname: Shimbo
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Watanabe
authors.forename: Tatsumi
authors.initials: T
authors.lastname: Abe
authors.forename: Teruki
authors.initials: T
authors.lastname: Sato
authors.forename: Takashi
authors.initials: T
authors.lastname: Koyama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ito
mesh_terms: D000667:Ampicillin / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications* / Q000382:microbiology / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D013407:Sulbactam / Q000008:administration & dosage*; D016896:Treatment Outcome; D014261:Tricuspid Valve / Q000382:microbiology* / Q000601:surgery; D014262:Tricuspid Valve Insufficiency / Q000209:etiology* / Q000382:microbiology / Q000503:physiopathology
chemical_list: D000900:Anti-Bacterial Agents; D000667:Ampicillin; D013407:Sulbactam