title: Association between trabecular bone score and risk factors for fractures in Korean female patients with rheumatoid arthritis.
abstract: OBJECTIVE
  To identify the association between trabecular bone score (TBS) and other known risk factors for fractures in rheumatoid arthritis (RA) patients.
  
  
  METHODS
  One hundred female RA patients aged ≥50 years were enrolled. The following risk factors for fracture were selected: prevalent vertebral fracture (VF), bone mineral density (BMD), TBS, and 10-year probability of major osteoporotic fracture by FRAX® (MOF-FRAX scores). The associations between risk factors were identified, and accuracy of TBS, BMD, and FRAX scores to detect the prevalent VF, the strongest risk factor for future fracture, were assessed.
  
  
  RESULTS
  Twenty-six patients were revealed to have moderate to severe VFs. There was a modest negative correlation between MOF-FRAX score and TBS (r =  -0.367, p < 0.01), while there was no correlation between MOF-FRAX score and L-spine BMD (r =  -0.050, p = 0.62). The areas under curves (AUCs) were 0.818, 0.683, and 0.518 for the MOF-FRAX score, TBS, and L-spine BMD, respectively. Among patients with glucocorticoids (GC) use (n = 57), AUCs were 0.762, 0.758, and 0.448 for their MOF-FRAX score, TBS, and L-spine BMD, respectively.
  
  
  CONCLUSIONS
  TBS showed better correlation with MOF-FRAX score than BMD, and it was superior to BMD in identifying prevalent VFs in RA patients, especially who are in use of GCs.
authors.affiliation: a Department of Rheumatology , Hanyang University Hospital for Rheumatic Diseases , Seoul , Republic of Korea .|b Clinical Research Center for Rheumatoid Arthritis (CRCRA) , Seoul , Republic of Korea , and.
authors.forename: Dam
authors.initials: D
authors.lastname: Kim
authors.affiliation: a Department of Rheumatology , Hanyang University Hospital for Rheumatic Diseases , Seoul , Republic of Korea .|b Clinical Research Center for Rheumatoid Arthritis (CRCRA) , Seoul , Republic of Korea , and.
authors.forename: Soo-Kyung
authors.initials: SK
authors.lastname: Cho
authors.affiliation: c Department of Nuclear Medicine , Hanyang University Hospital , Seoul , Republic of Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Kim
authors.affiliation: c Department of Nuclear Medicine , Hanyang University Hospital , Seoul , Republic of Korea.
authors.forename: Yun Young
authors.initials: YY
authors.lastname: Choi
authors.affiliation: a Department of Rheumatology , Hanyang University Hospital for Rheumatic Diseases , Seoul , Republic of Korea .|b Clinical Research Center for Rheumatoid Arthritis (CRCRA) , Seoul , Republic of Korea , and.
authors.forename: Yoon-Kyoung
authors.initials: YK
authors.lastname: Sung
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000000981:diagnostic imaging; D015519:Bone Density / Q000502:physiology*; D000071556:Cancellous Bone / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging / Q000209:etiology*; D018570:Risk Assessment; D012307:Risk Factors; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000209:etiology*
keywords: Arthritis; Bone; Bone density; Fractures; Rheumatoid; Risk assessment; Trabecular bone score