title: Management of acute severe ulcerative colitis (NICE CG 166).
abstract: Ulcerative colitis (UC) presents as an acute severe flare in 10-15% of new cases and it occurs in 15% of patients with established disease. Acute severe UC can lead to significant morbidity and mortality in predominantly younger patients without other comorbidities. Inpatient hospital admission and a multidisciplinary approach are vital in appropriate and timely management. Important but simple aspects in the initial work-up and treatment of such patients are frequently overlooked during the acute medical take. An overview of the general and more specialist management of this important presentation are discussed herein.
authors.affiliation: Tunbridge Wells Hospital at Pembury, Pembury, UK.
authors.forename: Lucia
authors.initials: L
authors.lastname: Macken
authors.affiliation: Tunbridge Wells Hospital at Pembury, Pembury, UK.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Blaker
mesh_terms: D000208:Acute Disease; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D006801:Humans
keywords: Ulcerative colitis; ciclosporin; colectomy; infliximab; severe