title: Taurodontism in patients with nonsyndromic cleft lip and palate in a Brazilian population: a case control evaluation with panoramic radiographs.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the prevalence of taurodontism in patients with nonsyndromic cleft lip and palate (NSCLP) within a Brazilian population.
  
  
  METHODS
  The study was designed as an epidemiologic case-control single-center study. Three hundred eighty-eight patients were included: 88 had NSCLP, and 300 comprised the control group. The first and second permanent mandibular molars were included in this study. By using panoramic radiographs, taurodontism was categorized as mesotaurodontism, hypotaurodontism, and hypertaurodontism.
  
  
  RESULTS
  Seventy patients (23.3%) from the control group and 36 patients (40.9%) from the case group presented taurodontism (P < .001). In the control group, 108 (9%) teeth showed taurodontism, whereas in the case group with cleft lip and palate (CLP), 64 (18.2%) teeth showed dental anomalies (P < .001). In both groups, most taurodontic teeth presented hypotaurodontism, followed by mesotaurodontism, while hypertaurodontism was found in only two teeth. The probability of taurodontism in patients with cleft lip (CL) was 2.36 (P = .010) times higher compared with those with CLP, whereas the occurrence of taurodontism in patients with cleft palate (CP) was 3.15 (P = .002) times greater than in patients with CLP.
  
  
  CONCLUSIONS
  The results from this study indicate a close relationship between taurodontism and NSCLP and the possibility of different cleft subphenotypes.
authors.affiliation: Professor Full of Dental School, University of Montes Claros, Montes Claros, Minas Gerais, Brazil. Electronic address: mariomelo@gmail.com.
authors.forename: Mario Rodrigues
authors.initials: MR
authors.lastname: Melo Filho
authors.affiliation: Professor Full of Dental School, University of Montes Claros, Montes Claros, Minas Gerais, Brazil.
authors.forename: Luis Antônio
authors.initials: LA
authors.lastname: Nogueira dos Santos
authors.affiliation: Professor Full of Dental School, University of Montes Claros, Montes Claros, Minas Gerais, Brazil.
authors.forename: Daniella Reis
authors.initials: DR
authors.lastname: Barbosa Martelli
authors.affiliation: Professor Associate of Math School, University of Montes Claros, Av Rui Braga - Vila Mauriceia - Campus Darcy Ribeiro - CEP 39401-089, Montes Claros, Minas Gerais, Brazil.
authors.forename: Marise Fagundes
authors.initials: MF
authors.lastname: Silveira
authors.affiliation: Dentist of the Center for Rehabilitation of Craniofacial Anomalies, Dental School, University of José Rosário Vellano, Minas Gerais, Brazil.
authors.forename: Myrian
authors.initials: M
authors.lastname: Esteves da Silva
authors.affiliation: Professor Associate of the Center for Rehabilitation of Craniofacial Anomalies, Dental School, University of José Rosário Vellano, Minas Gerais, Brazil.
authors.forename: Letízia Monteiro
authors.initials: LM
authors.lastname: de Barros
authors.affiliation: Professor Associate of the Department of Oral Diagnosis, School of Dentistry, State University of Campinas, São Paulo, Brazil.
authors.forename: Ricardo D
authors.initials: RD
authors.lastname: Coletta
authors.affiliation: Professor Full of Dental School, University of Montes Claros, Montes Claros, Minas Gerais, Brazil; Professor Associate of the Center for Rehabilitation of Craniofacial Anomalies, Dental School, University of José Rosário Vellano, Minas Gerais, Brazil.
authors.forename: Hercílio
authors.initials: H
authors.lastname: Martelli-Júnior
mesh_terms: D000293:Adolescent; D001938:Brazil / Q000453:epidemiology; D016022:Case-Control Studies; D002971:Cleft Lip / Q000453:epidemiology*; D002972:Cleft Palate / Q000453:epidemiology*; D003786:Dental Pulp Cavity / Q000002:abnormalities* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D011862:Radiography, Panoramic; D014071:Tooth Abnormalities / Q000145:classification / Q000000981:diagnostic imaging* / Q000453:epidemiology*