title: Paraneoplastic skin disorders: a review.
abstract: Paraneoplastic disorders are manifestations of internal malignancies without the direct action of the tumor. Its pathogenesis involves production of substances that interfere with cellular activity of distant tissues. Paraneoplasias may be the first sign of cancer, and clinicians should be familiarized with its manifestations in order to perform an early diagnosis of the underlying neoplasm. The aim of this review was to describe most common paraneoplastic skin diseases.
authors.affiliation: Department of Dermatology, University of São Paulo Medical School, São Paulo, Brazil - denisrmiyashiro@gmail.com.
authors.forename: Denis
authors.initials: D
authors.lastname: Miyashiro
authors.forename: Jose A
authors.initials: JA
authors.lastname: Sanches
mesh_terms: D000052:Acanthosis Nigricans / Q000175:diagnosis / Q000209:etiology; D015992:Body Mass Index; D001938:Brazil / Q000453:epidemiology; D003873:Dermatitis, Exfoliative / Q000175:diagnosis / Q000209:etiology; D003882:Dermatomyositis / Q000175:diagnosis / Q000209:etiology; D055088:Early Detection of Cancer; D006801:Humans; D006983:Hypertrichosis / Q000175:diagnosis / Q000209:etiology; D007333:Insulin Resistance; D009369:Neoplasms / Q000150:complications / Q000175:diagnosis; D009765:Obesity / Q000150:complications; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology; D012307:Risk Factors; D012871:Skin Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology*