title: Better Safe than Sorry: Interlinked Feedback Loops for Robust Mitophagy.
abstract: In this issue of Molecular Cell, Heo et al. (2015) uncover a new mechanism of signal amplification during mitophagy through cooperative regulation of the TBK1 kinase and autophagy receptors.
authors.affiliation: Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Manford
authors.affiliation: Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. Electronic address: mrape@berkeley.edu.
authors.forename: Michael
authors.initials: M
authors.lastname: Rape
mesh_terms: D006801:Humans; D008928:Mitochondria / Q000378:metabolism*; D063306:Mitophagy; D011494:Protein Kinases / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D044767:Ubiquitin-Protein Ligases / Q000378:metabolism*; D054875:Ubiquitination
chemical_list: D044767:Ubiquitin-Protein Ligases; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases