title: Genetics of endometriosis.
abstract: Endometriosis is a heritable complex disorder that is influenced by multiple genetic and environmental factors. Identification of these genetic factors will aid a better understanding of the underlying biology of the disease. In this article, we describe different methods of studying genetic variation of endometriosis, summarize results from genetic studies performed to date and provide recommendations for future studies to uncover additional factors contributing to the heritable component of endometriosis.
authors.affiliation: Wellcome Trust Center for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
authors.forename: Nilufer
authors.initials: N
authors.lastname: Rahmioglu
authors.affiliation: Molecular Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4029, Australia.
authors.forename: Grant W
authors.initials: GW
authors.lastname: Montgomery
authors.affiliation: Wellcome Trust Center for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.|Nuffield Department of Obstetrics & Gynaecology, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK.
authors.forename: Krina T
authors.initials: KT
authors.lastname: Zondervan
mesh_terms: D004715:Endometriosis / Q000235:genetics*; D004717:Endometrium / Q000473:pathology*; D005260:Female; D005786:Gene Expression Regulation; D020022:Genetic Predisposition to Disease; D006801:Humans; D007247:Infertility, Female / Q000235:genetics / Q000473:pathology*; D011110:Polymorphism, Genetic; D011960:Receptors, Estrogen / Q000235:genetics; D011980:Receptors, Progesterone / Q000235:genetics
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone
keywords: association studies; candidate gene studies; common genetic variants; functional studies; genome-wide association studies; linkage studies; rare genetic variants; rhesus macaque; sub-phenotype; twin studies