title: Prenylhydroquinone-Derived Secondary Metabolites from Cultures of the Basidiomycete Lentinus similis BCC 52578.
abstract: Two new prenylhydroquinone-derived compounds, Ientinospirol (1) and 1-(2,5-dihydroxyphenyl)-4-hydroxy-3-methyl-l-butanone (2), were isolated from cultures of the basidiomycete Lentinus similis BCC 52578, together with the known compounds panepoxydone (3), panepoxydione (4), isopanepoxydone (5), 2,2-dimethyl-6-hydroxy-2H-chromene (6), and (3R,4S)-3,4-dihydroxy-2,2-dimethyl-6-methoxychroman (7). Compounds 3 and 4 exhibited cytotoxicity against all cell-lines tested, while the other compounds were inactive.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Isaka
authors.forename: Somporn
authors.initials: S
authors.lastname: Palasarn
authors.forename: Malipan
authors.initials: M
authors.lastname: Sappana
authors.forename: Kitlada
authors.initials: K
authors.lastname: Srichomthong
authors.forename: Samantha C
authors.initials: SC
authors.lastname: Karunarathna
authors.forename: Kevin D
authors.initials: KD
authors.lastname: Hyde
mesh_terms: D006873:Hydroquinones / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D020074:Lentinula / Q000737:chemistry* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D064210:Secondary Metabolism
chemical_list: D006873:Hydroquinones; C031927:hydroquinone