title: Multispectral tissue characterization for intestinal anastomosis optimization.
abstract: Intestinal anastomosis is a surgical procedure that restores bowel continuity after surgical resection to treat intestinal malignancy, inflammation, or obstruction. Despite the routine nature of intestinal anastomosis procedures, the rate of complications is high. Standard visual inspection cannot distinguish the tissue subsurface and small changes in spectral characteristics of the tissue, so existing tissue anastomosis techniques that rely on human vision to guide suturing could lead to problems such as bleeding and leakage from suturing sites. We present a proof-of-concept study using a portable multispectral imaging (MSI) platform for tissue characterization and preoperative surgical planning in intestinal anastomosis. The platform is composed of a fiber ring light-guided MSI system coupled with polarizers and image analysis software. The system is tested on ex vivo porcine intestine tissue, and we demonstrate the feasibility of identifying optimal regions for suture placement.
authors.affiliation: Johns Hopkins University, Department of Electrical and Computer Engineering, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
authors.forename: Jaepyeong
authors.initials: J
authors.lastname: Cha
authors.affiliation: Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, 111 Michigan Avenue, Washington, DC 20010, United States.
authors.forename: Azad
authors.initials: A
authors.lastname: Shademan
authors.affiliation: Johns Hopkins University, Department of Electrical and Computer Engineering, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
authors.forename: Hanh N D
authors.initials: HN
authors.lastname: Le
authors.affiliation: Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, 111 Michigan Avenue, Washington, DC 20010, United States.
authors.forename: Ryan
authors.initials: R
authors.lastname: Decker
authors.affiliation: Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, 111 Michigan Avenue, Washington, DC 20010, United States.
authors.forename: Peter C W
authors.initials: PC
authors.lastname: Kim
authors.affiliation: Johns Hopkins University, Department of Electrical and Computer Engineering, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
authors.forename: Jin U
authors.initials: JU
authors.lastname: Kang
authors.affiliation: Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, 111 Michigan Avenue, Washington, DC 20010, United States.
authors.forename: Axel
authors.initials: A
authors.lastname: Krieger
mesh_terms: D000714:Anastomosis, Surgical / Q000295:instrumentation*; D000818:Animals; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D066298:In Vitro Techniques; D007422:Intestines / Q000473:pathology* / Q000601:surgery*; D008859:Microscopy, Polarization / Q000295:instrumentation*; D008866:Microsurgery / Q000295:instrumentation; D010865:Pilot Projects; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013057:Spectrum Analysis / Q000295:instrumentation; D025321:Surgery, Computer-Assisted / Q000295:instrumentation*; D013536:Suture Techniques / Q000295:instrumentation*; D013552:Swine; D016896:Treatment Outcome