title: Genotoxicity of Endodontic Materials: A Critical Review.
abstract: Genotoxicity is an action on cell's genetic material which may affect its integrity. This includes certain types of radiations and also certain chemical compounds. Genotoxic materials are those with affinity to interact with DNA but render them potentially carcinogenic or mutagenic. This review will address the genotoxicity of endodontic irrigants, medicaments and sealers.
authors.affiliation: Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iranian National Elites Foundation, Tehran Iran.
authors.forename: Zahed
authors.initials: Z
authors.lastname: Mohammadi
authors.affiliation: Private Dental Practice, Hamedan, Iran.
authors.forename: Sousan
authors.initials: S
authors.lastname: Shalavi
authors.affiliation: Associate Professor, Department of Endodontics, Dental Research Center Faculty of Dentistry, Mashhad University of Medical Sciences Mashhad, Iran, P.O. Box: 91735-984 Phone: +98-5138829501, e-mail: hamid_j365@yahoo.com, JafarzadehBH@mums.ac.ir.
authors.forename: Hamid
authors.initials: H
authors.lastname: Jafarzadeh
authors.affiliation: Department of Conservative Dentistry and Endodontics Faculty of Dental Sciences, MS Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
authors.forename: Shilpa
authors.initials: S
authors.lastname: Bhandi
authors.affiliation: Department of Oral and Maxillofacial Pathology, Faculty of Dental Sciences, MS Ramaiah University of Applied Sciences Bengaluru, Karnataka, India.
authors.forename: Shankargouda
authors.initials: S
authors.lastname: Patil
mesh_terms: D000818:Animals; D004249:DNA Damage / Q000187:drug effects*; D003764:Dental Materials / Q000009:adverse effects*; D006801:Humans; D012387:Root Canal Filling Materials / Q000009:adverse effects*
chemical_list: D003764:Dental Materials; D012387:Root Canal Filling Materials
keywords: Endodontics; Genotoxicity; Sealer