title: First trimester diagnosis of cervico-thoracic diastematomyelia and diplomyelia using three-dimensional ultrasound.
abstract: BACKGROUND
  Diastematomyelia and diplomyelia are rare form of spinal cord malformations (SCM) characterized by sagittal cleft in the spinal cord, conus medullaris, and/or filum terminale with splaying of the posterior vertebral elements and duplication of the spinal cord into two twin cords. Prenatal diagnosis of these diseases by two-dimensional ultrasound has been reported usually late in pregnancy and only recently in the first trimester.
  
  
  OBJECTIVE
  We describe the first case of cervico-thoracic diastematomyelia and diplomyelia diagnosed early in pregnancy using three-dimensional ultrasound.
authors.affiliation: Preconceptional and Prenatal Medicine, Department of Obstetrics and Gynecology, IRCCS Galliera Hospital, Genoa, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Lituania
authors.affiliation: Department of Obstetrics & Gynecology, AUSL Reggio Emilia, Guastalla Civil Hospital, Reggio Emilia, Italy.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Tonni
authors.affiliation: Department of Obstetrics, Paulista School of Medicine - Federal University of São Paulo (EPM-UNIFESP), Rua Belchior de Azevedo, 156 apto. 111 Torre Vitoria, São Paulo, SP, CEP 05089-030, Brazil. araujojred@terra.com.br.
authors.forename: Edward
authors.initials: E
authors.lastname: Araujo Júnior
mesh_terms: D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D009436:Neural Tube Defects / Q000150:complications / Q000175:diagnosis*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis; D013118:Spinal Cord Diseases / Q000150:complications / Q000175:diagnosis*; D016216:Ultrasonography, Prenatal; D055815:Young Adult
keywords: Diastematomyelia; Diplomyelia; First trimester of pregnancy; Prenatal diagnosis; Split cord malformation; Three-dimensional ultrasound