title: Pilot study of ultrasound parotid imaging reporting and data system (PIRADS): Inter-observer agreement.
abstract: OBJECTIVE
  To establish proposal ultrasound parotid imaging reporting and data system (PIRADS) for classification and prediction of malignancy of parotid lesions and to assess the inter-observer agreement of this system.
  
  
  METHODS
  Retrospective analysis of ultrasound and power Duplex images of 142 patients with parotid lesions by two reviewers. Parotid focal lesions were classified into nine patterns and then categorized into five groups: PIRADS 1, definitively benign; PIRADS 2, probably benign; PIRADS 3, indeterminate; PIRADS 4, probably malignant; and PIRADS 5, highly suggestive malignant.
  
  
  RESULTS
  There was excellent interobserver agreement of both reviewers for patterns and PIRADS (K=0.84, P=0.001) with 92% percent agreement. There was excellent agreement of PIRADS 1 (K=1.00, P=0.001), PIRADS 2 (K=0.97, P=0.001), PIRADS 3 (K=0.86, P=0.001) and PIRADS 5 (K=0.88, P=0.001) and good agreement of PIRADS 4 (K=0.67, P=0.001). The Odds ratio of PIRADS 3, 4 and 5 were 1.36 (95% CI=0.39-4.55), 7.11 (95% CI=3.02-11.15) and 8.27 (95% CI=3.49-10.27) respectively. The accuracy was 92% and 90%, sensitivity was 79% and 65%, specificity was 94% and 96% of PIRADS of both reviewers respectively.
  
  
  CONCLUSIONS
  The proposed PIRADS is a reliable non-invasive imaging modality that can be used for categorizing parotid lesions and prediction of malignancy.
authors.affiliation: Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura 13551, Egypt. Electronic address: arazek@mans.edu.eg.
authors.forename: Ahmed Abdel Khalek
authors.initials: AA
authors.lastname: Abdel Razek
authors.affiliation: Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura 13551, Egypt. Electronic address: germeenalbair@gmail.com.
authors.forename: Germeen Albair
authors.initials: GA
authors.lastname: Ashmalla
authors.affiliation: Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura 13551, Egypt. Electronic address: ghadagaballa@yahoo.com.
authors.forename: Gada
authors.initials: G
authors.lastname: Gaballa
authors.affiliation: Department of pathology, Mansoura faculty of medicine, Mansoura, Egypt. Electronic address: nadianada215@yahoo.com.
authors.forename: Nadia
authors.initials: N
authors.lastname: Nada
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010306:Parotid Gland / Q000000981:diagnostic imaging*; D010307:Parotid Neoplasms / Q000000981:diagnostic imaging*; D010865:Pilot Projects; D011873:Radiology Information Systems / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D055815:Young Adult
keywords: Benign; Malignant; Parotid; Salivary; Tumor; Ultrasound