title: Norovirus Antigen Detection with a Combination of Monoclonal and Single-Chain Antibodies.
abstract: The performance of a norovirus antigen detection assay was assessed using monoclonal antibody NV23 and single-chain antibody HJT-R3-A9 to identify both virus-like particles and virus-containing fecal samples. The detection of 25 different norovirus genotypes as recombinant virus-like particles or in clinical samples was dependent on virus or antigen concentration.
authors.affiliation: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Baijun
authors.initials: B
authors.lastname: Kou
authors.affiliation: Department of Pharmacology, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Wanzhi
authors.initials: W
authors.lastname: Huang
authors.affiliation: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Frederick H
authors.initials: FH
authors.lastname: Neill
authors.affiliation: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA Department of Pharmacology, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Timothy
authors.initials: T
authors.lastname: Palzkill
authors.affiliation: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Mary K
authors.initials: MK
authors.lastname: Estes
authors.affiliation: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA Department of Medicine, Baylor College of Medicine, Houston, Texas, USA ratmar@bcm.edu.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Atmar
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology*; D000956:Antigens, Viral / Q000032:analysis*; D017250:Caliciviridae Infections / Q000175:diagnosis*; D005243:Feces / Q000821:virology*; D006801:Humans; D029322:Norovirus / Q000302:isolation & purification*; D057127:Single-Chain Antibodies / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D057127:Single-Chain Antibodies