title: Meta-analysis of Failure and Survival Rate of Implant-supported Single Crowns, Fixed Partial Denture, and Implant Tooth-supported Prostheses.
abstract: BACKGROUND
  Dental implants have become the most viable option for rehabilitation. Although, many studies report the success of these reconstructions using implants, a cumulative data about the various studies and the failure rate still remain unaddressed. Therefore, the purpose of this systematic review was to analyze these data and to derive the cumulative survival rate of different implant-supported prosthesis.
  
  
  METHODS
  Manual searches followed by a MEDLINE search were conducted to select prospective and retrospective cohort studies on single crowns (SCs), fixed partial denture (FPD), and tooth implant connected prostheses with a mean follow-up time of minimum of 5 years. Random-effects Poisson's regression models have been used to obtain summary estimates for implant failure and survival rates.
  
  
  RESULTS
  Data were extracted from the final selected 63 studies. In a meta-analysis of these studies, the survival rate of SCs supported by implants (95% CI) was 96.363%, for FPDs was 94.525% and implant tooth-supported prostheses was 91.27% after 5 years of function. The cumulative failure rate per 100 FPD years of the SCs, FPDs, and implant tooth-supported prostheses were 0.684, 0.881, and 1.514, respectively.
  
  
  CONCLUSIONS
  The study concludes high survival rates for implant-supported SCs followed by implant-supported FPDs can be expected over an observation period of 5 years. However, tooth implant-supported prostheses can be provided if there are certain limitations prohibiting the completely implant-supported prostheses.
authors.affiliation: Reader, Department of Prosthodontics including Crown and Bridge and Implantology, M R Ambedkar Dental College and Hospital, Bengaluru, Karnataka, India.
authors.forename: B C
authors.initials: BC
authors.lastname: Muddugangadhar
authors.affiliation: Professor and Head, Department of Prosthodontics including Crown and Bridge and Implantology, M R Ambedkar Dental College and Hospital, Bengaluru, Karnataka, India.
authors.forename: G S
authors.initials: GS
authors.lastname: Amarnath
authors.affiliation: Post Graduate Student, Department of Prosthodontics including Crown and Bridge and Implantology, M R Ambedkar Dental College and Hospital, Bengaluru, Karnataka, India.
authors.forename: Radhika
authors.initials: R
authors.lastname: Sonika
authors.affiliation: Senior Lecturer, Department of Prosthodontics including Crown and Bridge and Implantology, Guardian College of Dental Sciences, Ambernath, Thane, Mumbai, India.
authors.forename: Pratik S
authors.initials: PS
authors.lastname: Chheda
authors.affiliation: Post Graduate Student, Department of Prosthodontics including Crown and Bridge and Implantology, M R Ambedkar Dental College and Hospital, Bengaluru, Karnataka, India.
authors.forename: Ashu
authors.initials: A
authors.lastname: Garg
keywords: Case-control; cohort; failure; implants; survival