title: CT-Guided Percutaneous Step-by-Step Radiofrequency Ablation for the Treatment of Carcinoma in the Caudate Lobe.
abstract: The location of the caudate lobe and its complex anatomy make caudate lobectomy and radiofrequency ablation (RFA) under ultrasound guidance technically challenging. The objective of the exploratory study was to introduce a novel modality of treatment of lesions in caudate lobe and discuss all details with our experiences to make this novel treatment modality repeatable and educational. The study enrolled 39 patients with liver caudate lobe tumor first diagnosed by computerized tomography (CT) or magnetic resonance imaging (MRI). After consultation of multi-disciplinary team, 7 patients with hepatic caudate lobe lesions were enrolled and accepted CT-guided percutaneous step-by-step RFA treatment. A total of 8 caudate lobe lesions of the 7 patients were treated by RFA in 6 cases and RFA combined with percutaneous ethanol injection (PEI) in 1 case. Median tumor diameter was 29 mm (range, 18-69 mm). A right approach was selected for 6 patients and a dorsal approach for 1 patient. Median operative time was 64 min (range, 59-102 min). Median blood loss was 10 mL (range, 8-16 mL) and mainly due to puncture injury. Median hospitalization time was 4 days (range, 2-5 days). All lesions were completely ablated (8/8; 100%) and no recurrence at the site of previous RFA was observed during median 8 months follow-up (range 3-11 months). No major or life-threatening complications or deaths occurred. In conclusion, percutaneous step-by-step RFA under CT guidance is a novel and effective minimally invasive therapy for hepatic caudate lobe lesions with well repeatability.
authors.affiliation: From the Department of Medical Imaging & Image Guided Therapy, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, East Dong Feng Road 651, Guangzhou, Guangdong 510060, PR China (JD, WL, QZ, SL, LS, SM, AD, PW); and Department of Medical Statistics and Epidemiology School of Public Health, Sun Yat-sen University, Zhongshan 2nd Road, 74, Guangzhou, Guangdong 510080, PR China (XG).
authors.forename: Jun
authors.initials: J
authors.lastname: Dong
authors.forename: Wang
authors.initials: W
authors.lastname: Li
authors.forename: Qi
authors.initials: Q
authors.lastname: Zeng
authors.forename: Sheng
authors.initials: S
authors.lastname: Li
authors.forename: Xiao
authors.initials: X
authors.lastname: Gong
authors.forename: Lujun
authors.initials: L
authors.lastname: Shen
authors.forename: Siyue
authors.initials: S
authors.lastname: Mao
authors.forename: Annan
authors.initials: A
authors.lastname: Dong
authors.forename: Peihong
authors.initials: P
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D061646:Operative Time; D015641:Radiography, Interventional / Q000379:methods*; D014057:Tomography, X-Ray Computed