title: A Novel C21 Cyclopentenone Derivative from Cipadessa cinerascens.
abstract: A new C21 cyclopentenone derivative, Cipacyclonone (1), was isolated from the leaves of Cipadessa cinerascens. Its structure was elucidated on the basis of spectroscopic analysis, including extensive 1D- and 2D-NMR techniques. Compound 1 showed strong cytotoxicity activity against HL-60 and A-549 cell lines, with IC50 values of 1.2 and 3.0 microM, respectively.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Yao-Wen
authors.initials: YW
authors.lastname: Chang
authors.forename: Chun-Mao
authors.initials: CM
authors.lastname: Yuan
authors.forename: Fan
authors.initials: F
authors.lastname: Zhang
authors.forename: Ying-Tong
authors.initials: YT
authors.lastname: Di
authors.forename: Xiao-Jiang
authors.initials: XJ
authors.lastname: Hao
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D003517:Cyclopentanes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D029582:Meliaceae / Q000737:chemistry*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D003517:Cyclopentanes; D004365:Drugs, Chinese Herbal; C013905:cyclopentenone