title: Port type is a possible risk factor for implantable venous access port-related bloodstream infections and no sign of local infection predicts the growth of gram-negative bacilli.
abstract: BACKGROUND
  Implantable venous access port (IVAP)-related blood stream infections (BSIs) are one of the most common complications of implantable venous ports. The risk factors and pathogens for IVAP-related BSIs are still controversial.
  
  
  METHODS
  We retrospectively reviewed all patients who received IVAPs at a Hospital in Taiwan from January 1, 2011 to June 31, 2014. Two types of venous port, BardPort® 6.6 fr (Bard port) and Autosuture Chemosite® 7.5 fr (TYCO port) were used. All patients with clinically proven venous port-related BSIs were enrolled.
  
  
  RESULTS
  A total of 552 patients were enrolled. There were 34 episodes of IVAP-related BSIs during the study period for a total incidence of 0.177 events/1000 catheter days. Port type (TYCO vs. Bard, HR = 7.105 (95% confidence interval (CI), 1.688-29.904), p = 0.0075), age > 65 years (HR = 2.320 (95 % CI, 1.179-4.564), p = 0.0148), and lung cancer (HR = 5.807 (95% CI, 2.946-11.447), p < 0.001) were risk factors for port infections. We also found that no local sign of infection was significantly associated with the growth of gram-negative bacilli (p = 0.031).
  
  
  CONCLUSIONS
  TYCO venous ports, age > 65 years, and lung cancer were all significant risk factors for IVAP-related BSIs, and no sign of infection was significantly associated with the growth of gram-negative bacilli.
authors.affiliation: Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, No. 68 Chunghwa 3rd Road, Cianjin District, 80145, Kaohsiung City, Taiwan. 940360@mail.kmuh.org.tw.
authors.forename: Jui-Feng
authors.initials: JF
authors.lastname: Hsu
authors.affiliation: Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, No. 68 Chunghwa 3rd Road, Cianjin District, 80145, Kaohsiung City, Taiwan. hsliac@cc.kmu.edu.tw.
authors.forename: Hsu-Liang
authors.initials: HL
authors.lastname: Chang
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. SiegfriedTsai@gmail.com.
authors.forename: Ming-Ju
authors.initials: MJ
authors.lastname: Tsai
authors.affiliation: Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, No. 68 Chunghwa 3rd Road, Cianjin District, 80145, Kaohsiung City, Taiwan. yingming@kmu.edu.tw.
authors.forename: Ying-Ming
authors.initials: YM
authors.lastname: Tsai
authors.affiliation: Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. 920266@mail.kmuh.org.tw.
authors.forename: Yen-Lung
authors.initials: YL
authors.lastname: Lee
authors.affiliation: Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. c0917jre@ms5.hinet.net.
authors.forename: Pei-Huan
authors.initials: PH
authors.lastname: Chen
authors.affiliation: Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. tomato@gmail.com.
authors.forename: Wen-Chieh
authors.initials: WC
authors.lastname: Fan
authors.affiliation: Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, No. 68 Chunghwa 3rd Road, Cianjin District, 80145, Kaohsiung City, Taiwan. ycsu@cc.kmu.edu.tw.
authors.forename: Yu-Chung
authors.initials: YC
authors.lastname: Su
authors.affiliation: Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, No. 68 Chunghwa 3rd Road, Cianjin District, 80145, Kaohsiung City, Taiwan. chjeya@cc.kmu.edu.tw.|Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. chjeya@cc.kmu.edu.tw.|School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. chjeya@cc.kmu.edu.tw.
authors.forename: Chih-Jen
authors.initials: CJ
authors.lastname: Yang
mesh_terms: D000368:Aged; D055499:Catheter-Related Infections / Q000453:epidemiology* / Q000382:microbiology; D002408:Catheters, Indwelling / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006090:Gram-Negative Bacteria / Q000254:growth & development*; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D006801:Humans; D015994:Incidence; D008297:Male; D009369:Neoplasms / Q000150:complications* / Q000628:therapy; D011379:Prognosis; D012189:Retrospective Studies; D013624:Taiwan / Q000453:epidemiology; D062666:Vascular Access Devices / Q000009:adverse effects* / Q000145:classification