title: Lewis acid-promoted [2 + 2] cycloadditions of alkenes with aryl ketenes.
abstract: A method for the [2 + 2] cycloaddition of aryl ketenes and alkenes is presented. The process involves the in situ generation of a ketene in the presence of a Lewis acid. The utility of products is demonstrated towards the synthesis of a common scaffold found in several natural product families.
authors.affiliation: SSCI, A Division of Albany Molecular Research Inc, 3065 Kent Avenue West Lafayette, IN 47906-1076, USA.
authors.forename: E M
authors.initials: EM
authors.lastname: Rigsbee
authors.forename: C
authors.initials: C
authors.lastname: Zhou
authors.forename: C M
authors.initials: CM
authors.lastname: Rasik
authors.forename: A Z
authors.initials: AZ
authors.lastname: Spitz
authors.forename: A J
authors.initials: AJ
authors.lastname: Nichols
authors.forename: M K
authors.initials: MK
authors.lastname: Brown