title: Breakdown of Bragg-Gray behaviour for low-density detectors under electronic disequilibrium conditions in small megavoltage photon fields.
abstract: In small photon fields ionisation chambers can exhibit large deviations from Bragg-Gray behaviour; the EGSnrc Monte Carlo (MC) code system has been employed to investigate this 'Bragg-Gray breakdown'. The total electron (+positron) fluence in small water and air cavities in a water phantom has been computed for a full linac beam model as well as for a point source spectrum for 6 MV and 15 MV qualities for field sizes from 0.25  ×  0.25 cm(2) to 10  ×  10 cm(2). A water-to-air perturbation factor has been derived as the ratio of total electron (+positron) fluence, integrated over all energies, in a tiny water volume to that in a 'PinPoint 3D-chamber-like' air cavity; for the 0.25  ×  0.25 cm(2) field size the perturbation factors are 1.323 and 2.139 for 6 MV and 15 MV full linac geometries respectively. For the 15 MV full linac geometry for field sizes of 1  ×  1 cm(2) and smaller not only the absolute magnitude but also the 'shape' of the total electron fluence spectrum in the air cavity is significantly different to that in the water 'cavity'. The physics of this 'Bragg-Gray breakdown' is fully explained, making reference to the Fano theorem. For the 15 MV full linac geometry in the 0.25  ×  0.25 cm(2) field the directly computed MC dose ratio, water-to-air, differs by 5% from the product of the Spencer-Attix stopping-power ratio (SPR) and the perturbation factor; this 'difference' is explained by the difference in the shapes of the fluence spectra and is also formulated theoretically. We show that the dimensions of an air-cavity with a perturbation factor within 5% of unity would have to be impractically small in these highly non-equilibrium photon fields. In contrast the dose to water in a 0.25  ×  0.25 cm(2) field derived by multiplying the dose in the single-crystal diamond dosimeter (SCDDo) by the Spencer-Attix ratio is within 2.9% of the dose computed directly in the water voxel for full linac geometry at both 6 and 15 MV, thereby demonstrating that this detector exhibits quasi Bragg-Gray behaviour over a wide range of field sizes and beam qualities.
authors.affiliation: Department of Physics, Clatterbridge Cancer Centre, Bebington CH63 4JY, UK. Department of Physics, University of Liverpool, Liverpool L69 7ZE, UK. Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, CT & CRS building, Anushaktinagar, Mumbai-400094, India. Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai-400 094, India.
authors.forename: Sudhir
authors.initials: S
authors.lastname: Kumar
authors.forename: John D
authors.initials: JD
authors.lastname: Fenwick
authors.forename: Tracy S A
authors.initials: TS
authors.lastname: Underwood
authors.forename: Deepak D
authors.initials: DD
authors.lastname: Deshpande
authors.forename: Alison J D
authors.initials: AJ
authors.lastname: Scott
authors.forename: Alan E
authors.initials: AE
authors.lastname: Nahum
mesh_terms: D004583:Electrons; D006801:Humans; D008962:Models, Theoretical; D009010:Monte Carlo Method; D010315:Particle Accelerators / Q000295:instrumentation*; D019047:Phantoms, Imaging; D017785:Photons; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods; D014867:Water / Q000737:chemistry
chemical_list: D014867:Water