title: Air pollution and fasting blood glucose: A longitudinal study in China.
abstract: Limited studies have examined the associations between air pollutants [particles with diameters of 10 μm or less (PM10), sulphur dioxide (SO2), and nitrogen dioxide (NO2)] and fasting blood glucose (FBG). We collected data for 27,685 participants who were followed during 2006 and 2008. Generalized Estimating Equation models were used to examine the effects of air pollutants on FBG while controlling for potential confounders. We found that increased exposure to NO2, SO2 and PM10 was significantly associated with increased FBG levels in single pollutant models (p<0.001). For exposure to 4 days' average of concentrations, a 100 μg/m(3) increase in SO2, NO2, and PM10 was associated with 0.17 mmol/L (95% CI: 0.15-0.19), 0.53 mmol/L (95% CI: 0.42-0.65), and 0.11 mmol/L (95% CI: 0.07-0.15) increase in FBG, respectively. In the multi-pollutant models, the effects of SO2 were enhanced, while the effects of NO2 and PM10 were alleviated. The effects of air pollutants on FBG were stronger in female, elderly, and overweight people than in male, young and underweight people. In conclusion, the findings suggest that air pollution increases the levels of FBG. Vulnerable people should pay more attention on highly polluted days to prevent air pollution-related health issues.
authors.affiliation: Division of Epidemiology and Biostatistics, School of Public Health, University of Queensland, Brisbane, Australia.
authors.forename: Linping
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Division of Epidemiology and Biostatistics, School of Public Health, University of Queensland, Brisbane, Australia.
authors.forename: Shanshan
authors.initials: S
authors.lastname: Li
authors.affiliation: Division of Epidemiology and Biostatistics, School of Public Health, University of Queensland, Brisbane, Australia.
authors.forename: Gail
authors.initials: G
authors.lastname: Williams
authors.affiliation: School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, China.
authors.forename: Haidong
authors.initials: H
authors.lastname: Kan
authors.affiliation: Woolcock Institute of Medical Research, 431 Glebe Point Road, Glebe, New South Wales, Australia; South Western Sydney Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
authors.forename: Guy B
authors.initials: GB
authors.lastname: Marks
authors.affiliation: International Laboratory for Air Quality and Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
authors.forename: Lidia
authors.initials: L
authors.lastname: Morawska
authors.affiliation: Department of Epidemiology & Preventive Medicine, School of Public Health & Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Abramson
authors.affiliation: Department of Cardiology, Kailuan General Hospital, Tangshan, Hebei Province, China.
authors.forename: Shuohua
authors.initials: S
authors.lastname: Chen
authors.affiliation: Department of Occupational Disease Prevention and Treatment, Kailuan General Hospital, Tangshan, Hebei Province, China.
authors.forename: Taicheng
authors.initials: T
authors.lastname: Yao
authors.affiliation: Department of Occupational Disease Prevention and Treatment, Kailuan General Hospital, Tangshan, Hebei Province, China.
authors.forename: Tianbang
authors.initials: T
authors.lastname: Qin
authors.affiliation: Department of Cardiology, Kailuan General Hospital, Tangshan, Hebei Province, China. Electronic address: drwusl@163.com.
authors.forename: Shouling
authors.initials: S
authors.lastname: Wu
authors.affiliation: Division of Epidemiology and Biostatistics, School of Public Health, University of Queensland, Brisbane, Australia. Electronic address: y.guo1@uq.edu.au.
authors.forename: Yuming
authors.initials: Y
authors.lastname: Guo
mesh_terms: D000328:Adult; D000368:Aged; D000393:Air Pollutants / Q000032:analysis; D000397:Air Pollution / Q000706:statistics & numerical data*; D001786:Blood Glucose / Q000502:physiology*; D002681:China; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D005215:Fasting; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D015233:Models, Statistical; D009585:Nitrogen Dioxide / Q000032:analysis; D052638:Particulate Matter; D013458:Sulfur Dioxide; D055815:Young Adult
chemical_list: D000393:Air Pollutants; D001786:Blood Glucose; D052638:Particulate Matter; D013458:Sulfur Dioxide; D009585:Nitrogen Dioxide
keywords: Air pollution; Cohort study; Diabetes; Fasting Blood Glucose; Nitrogen dioxide; Particles; Sulphur dioxide