title: [Early neonatal sepsis, incidence and associated risk factors in a public hospital in western Mexico].
abstract: BACKGROUND
  Early neonatal sepsis (EOS) is the second leading cause of death in the first week of life. Epidemiology differs in developed and developing countries.
  
  
  OBJECTIVE
  To describe the epidemiology of EOS among newborn patients in a public hospital in western Mexico.
  
  
  METHODS
  A prospective cohort study was performed in newborns of Nuevo Hospital Civil de Guadalajara "Dr. Juan I Menchaca". EOS was diagnosed with blood cultures or cultures of cerebrospinal fluid within the first 72 h of life. We analyzed risk factors (RF) by multivariate analysis with logistic regression.
  
  
  RESULTS
  We identified an EOS incidence of 4.7 events per 1,000 live births. Seventy two percent of the isolated bacteria were gram negative bacilli. Factors associated with EOS were maternal age≤15 years (OR 3.50; 95% CI 1.56-7.85), rupture of membranes>18 h (OR 2.65; 95% CI 1.18-5.92), maternal fever (OR 6.04; 95% CI 1.54-23.6), birth weight≤2,500 g (OR 4.82; 95% CI 2.38-9.75) and gestational age<37 weeks (OR 3.14; 95% CI 1.58-6.22).
  
  
  CONCLUSIONS
  In addition to the RF known for EOS an independent association was observed with maternal age≤15 years.
authors.forename: René Oswaldo
authors.initials: RO
authors.lastname: Pérez
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Lona
authors.forename: Moisés
authors.initials: M
authors.lastname: Quiles
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Verdugo
authors.forename: Elba Patricia
authors.initials: EP
authors.lastname: Ascencio
authors.forename: Edith Adriana
authors.initials: EA
authors.lastname: Benítez
mesh_terms: D001724:Birth Weight; D004755:Enterobacteriaceae / Q000145:classification / Q000302:isolation & purification; D016983:Enterococcus / Q000145:classification / Q000302:isolation & purification; D005260:Female; D005865:Gestational Age; D006779:Hospitals, Public; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D016015:Logistic Models; D008297:Male; D008800:Mexico / Q000453:epidemiology; D015999:Multivariate Analysis; D011446:Prospective Studies; D012307:Risk Factors; D018805:Sepsis / Q000453:epidemiology* / Q000382:microbiology; D013291:Streptococcus / Q000145:classification / Q000302:isolation & purification