title: Is Caenorhabditis elegans the Magic Bullet for Anthelminthic Drug Discovery?
abstract: Recent advances in handling and readout have facilitated high-throughput screens with Caenorhabditis elegans. A new study demonstrates that C. elegans is a useful tool in high-throughput anthelminthic drug discovery. Despite challenges, drug discovery using C. elegans offers opportunities that might lead the way to novel anthelminthic drugs.
authors.affiliation: Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address: Jennifer.keiser@unibas.ch.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Keiser
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D017173:Caenorhabditis elegans / Q000187:drug effects*; D055808:Drug Discovery; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D021261:Parasitic Sensitivity Tests
chemical_list: D000871:Anthelmintics
keywords: Caenorhabditis elegans; anthelminthics; drug discovery