title: [The Hemodynamics and Bispectral Index Score during Lower Abdominal Surgery under Balanced Anesthesia with the Two Different Combination Doses of Desflurane and Remifentanil].
abstract: BACKGROUND
  The purpose of this study was to examine the hemodynamics and bispectral index score during lower abdominal surgery under balanced anesthesia with the two different combination doses of desflurane and remifentanil.
  
  
  METHODS
  Twenty patients undergoing total hysterectomy were allocated into two groups; 1) 10 patients received 4.5% end-tidal concentration of desflurane combined with remifentanil 0.125 μg x kg(-1) x min(-1) (H group) and 2) 10 patients received 3.0% end-tidal concentration of desflurane combined with remifentanil 0.2 μg x kg(-1) X min(-1) (L group). Mean arterial pressure (MAP), heart rate (HR) and BIS were recorded 5 times (on admission to operating room, immediately before surgery, 5 minutes after the skin incision, at the moment of uterine extraction and during retroperitoneal closure).
  
  
  RESULTS
  MAP and HR during surgery did not increase compared with those on admission to operating room, and BIS was unchanged throughout the study in both two groups.
  
  
  CONCLUSIONS
  The patients could be anesthetized adequately during lower abdominal surgery under balanced anesthesia with the two different combination doses of desflurane and remifentanil.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Nishiyama
mesh_terms: D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000493:pharmacokinetics*; D018686:Anesthetics, Intravenous / Q000493:pharmacokinetics*; D058126:Balanced Anesthesia; D000077335:Desflurane; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007530:Isoflurane / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D007889:Leiomyoma / Q000601:surgery*; D010880:Piperidines / Q000008:administration & dosage / Q000493:pharmacokinetics*; D000077208:Remifentanil
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077335:Desflurane; D007530:Isoflurane; D000077208:Remifentanil