title: Clear Cell Sarcoma Of Metatarsus.
abstract: We report a case of clear cell sarcoma in the third metatarsus of the right foot. This type of tumor is very rare and scantily reported in literature. A 42-year-old Caucasian male presented with a nodular ulcerated mass on the dorsal side of the left foot. X-rays demonstrated a nodular solid lesion which dislodged the third metatarsus. A biopsy revealed a neoplastic proliferation with a sarcoma clear cell profile; because of the aggressive nature of this type of neoplasm, we performed a trans-tibial amputation according to Bugess to achieve a better functionality for the patient. The present study underlines clinical, morphological, as well as imaging and therapeutic aspects of a rare neoplasm such as clear cell sarcoma. The location site is also quite unusual - the metatarsus of the foot. The histological and immunohistochemical data were suggestive of the diagnosis of clear cell sarcoma of metatarsus. After MRI and a bone scan, the surgical treatment suggested the extension over the forefoot and the ankle and therefore a trans-tibial amputation was made.
authors.affiliation: Department of Human Pathology, Section of Pathological Anatomy, Azienda Ospedaliera Universitaria Policlinico G. Martino, Messina, Italy
authors.forename: Luana
authors.initials: L
authors.lastname: Licata
authors.affiliation: Department of Biomedical Sciences, Morphological and Functional Imaging, Section of Orthopaedics and Traumatology, Azienda Ospedaliera Universitaria Policlinico G. Martino, Messina, Italy
authors.forename: Domenico
authors.initials: D
authors.lastname: Fenga
authors.affiliation: Department of Human Pathology, Section of Pathological Anatomy, Azienda Ospedaliera Universitaria Policlinico G. Martino, Messina, Italy
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Speciale
authors.affiliation: Department of Biomedical Sciences, Morphological and Functional Imaging, Section of Orthopaedics and Traumatology, Azienda Ospedaliera Universitaria Policlinico G. Martino, Messina, Italy
authors.forename: Michele Attilio
authors.initials: MA
authors.lastname: Rosa
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D008684:Metatarsus / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D018227:Sarcoma, Clear Cell / Q000175:diagnosis* / Q000601:surgery