title: Prenatal diagnosis and outcomes of fetal teratomas.
abstract: OBJECTIVE
  Our aim was to evaluate the diagnostic performance of ultrasonography (US) in the prenatal identification of teratomas and the perinatal outcome of the fetuses with those teratomas.
  
  
  METHODS
  In this retrospective case series study, we searched the archives using the keywords "fetal mass" or "fetal tumor" or "fetal teratoma" and "sacrococcygeal teratoma," diagnosed between 2009 and 2014, within the US database of our center.
  
  
  RESULTS
  One hundred seven fetuses were prenatally diagnosed as having a cystic or solid mass, tumor, or teratoma. Nineteen of those cases were diagnosed prenatally as having fetal teratoma, but that diagnosis could not be verified in three cases. In one fetus, the prenatal diagnosis could not be confirmed. The sensitivity of US in identifying fetal teratoma was 100% and the false-positive rate, 3.3%. Six pregnancies complicated by a fetal teratoma were terminated. A normal karyotype was identified in all fetuses that underwent karyotyping. Among the nine women who continued their pregnancy, polyhydramnios was identified in four fetuses; although high-output heart failure was also identified in two of those fetuses during prenatal follow-up, none developed hydrops. On delivery, nine infants were born alive, but three (33.3%) of them died within the early neonatal period.
  
  
  CONCLUSIONS
  US has very high sensitivity and low false-positive rates in identifying fetal teratoma prenatally. The risk of chromosomal abnormalities is very low in fetuses with teratoma, and their prognosis depends on the location and size of the tumor and any associated perinatal complications.
authors.affiliation: Department of Perinatology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Resul
authors.initials: R
authors.lastname: Arisoy
authors.affiliation: Department of Perinatology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Erdogdu
authors.affiliation: Department of Perinatology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Kumru
authors.affiliation: Department of Perinatology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Oya
authors.initials: O
authors.lastname: Demirci
authors.affiliation: Department of Obstetrics and Gynecology, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Nida
authors.initials: N
authors.lastname: Ergin
authors.affiliation: Department of Perinatology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Oya
authors.initials: O
authors.lastname: Pekin
authors.affiliation: Department of Perinatology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Zeki
authors.initials: Z
authors.lastname: Sahinoglu
authors.affiliation: Department of Perinatology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Ahmet Semih
authors.initials: AS
authors.lastname: Tugrul
authors.affiliation: Department of Neonatology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Selim
authors.initials: S
authors.lastname: Sancak
authors.affiliation: Department of Pathology, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Handan
authors.initials: H
authors.lastname: Çetiner
authors.affiliation: Department of Pediatric Surgery, Zeynep Kamil Maternity and Children's Training and Research Hospital, Istanbul, Turkey.
authors.forename: Aysenur
authors.initials: A
authors.lastname: Celayir
mesh_terms: D000328:Adult; D019992:Databases as Topic; D005260:Female; D006801:Humans; D007223:Infant; D011247:Pregnancy; D012189:Retrospective Studies; D018243:Teratocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D016216:Ultrasonography, Prenatal
keywords: fetal teratoma; outcome; prenatal counseling; prenatal diagnosis; ultrasonography