title: Aortic and Mitral Valve Replacement Due to Extensive Inflammatory Immunoglobulin G4-Related Pseudotumor.
abstract: A 64-year-old woman with extensive tumorous infiltration of the mitral and aortic valves underwent partial resection of a tumor of the left ventricular outflow tract and replacement of both affected valves. Histology revealed an inflammatory pseudotumor with a significant number of immunoglobulin-G4-positive plasma cells. The histologic and clinical findings suggested immunoglobulin-G4-related disease of the heart.
authors.affiliation: Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic. Electronic address: josef.besik@ikem.cz.
authors.forename: Josef
authors.initials: J
authors.lastname: Besik
authors.affiliation: Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Pirk
authors.affiliation: Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Ivan
authors.initials: I
authors.lastname: Netuka
authors.affiliation: Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Ondrej
authors.initials: O
authors.lastname: Szarszoi
authors.affiliation: Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Tomas
authors.initials: T
authors.lastname: Marek
authors.affiliation: Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Marian
authors.initials: M
authors.lastname: Urban
authors.affiliation: Department of Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Eva
authors.initials: E
authors.lastname: Honsova
authors.affiliation: The Fingerland Department of Pathology, Charles University in Prague, Faculty of Medicine and University Hospital Hradec Kralove, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Laco
mesh_terms: D001021:Aortic Valve / Q000601:surgery*; D005260:Female; D006104:Granuloma, Plasma Cell / Q000150:complications* / Q000276:immunology; D006349:Heart Valve Diseases / Q000209:etiology* / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007074:Immunoglobulin G; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*
chemical_list: D007074:Immunoglobulin G