title: Brain palpation from physiological vibrations using MRI.
abstract: We present a magnetic resonance elastography approach for tissue characterization that is inspired by seismic noise correlation and time reversal. The idea consists of extracting the elasticity from the natural shear waves in living tissues that are caused by cardiac motion, blood pulsatility, and any muscle activity. In contrast to other magnetic resonance elastography techniques, this noise-based approach is, thus, passive and broadband and does not need any synchronization with sources. The experimental demonstration is conducted in a calibrated phantom and in vivo in the brain of two healthy volunteers. Potential applications of this "brain palpation" approach for characterizing brain anomalies and diseases are foreseen.
authors.affiliation: Inserm, U1032, LabTau, Lyon, F-69003, France; Université Lyon 1, Lyon, F-69003, France;
authors.forename: Ali
authors.initials: A
authors.lastname: Zorgani
authors.affiliation: Inserm, U1032, LabTau, Lyon, F-69003, France; Université Lyon 1, Lyon, F-69003, France;
authors.forename: Rémi
authors.initials: R
authors.lastname: Souchon
authors.affiliation: Inserm, U1032, LabTau, Lyon, F-69003, France; Université Lyon 1, Lyon, F-69003, France;
authors.forename: Au-Hoang
authors.initials: AH
authors.lastname: Dinh
authors.affiliation: Inserm, U1032, LabTau, Lyon, F-69003, France; Université Lyon 1, Lyon, F-69003, France;
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Chapelon
authors.affiliation: Centre Radiologie Imagerie par Résonance Magnétique (IRM) Préssensé, Villeurbanne, F-69100, France;
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Ménager
authors.affiliation: Centre Radiologie Imagerie par Résonance Magnétique (IRM) Préssensé, Villeurbanne, F-69100, France;
authors.forename: Samir
authors.initials: S
authors.lastname: Lounis
authors.affiliation: Inserm, U1032, LabTau, Lyon, F-69003, France; Université Lyon 1, Lyon, F-69003, France; Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, F-69003, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Rouvière
authors.affiliation: Inserm, U1032, LabTau, Lyon, F-69003, France; Université Lyon 1, Lyon, F-69003, France; stefan.catheline@inserm.fr.
authors.forename: Stefan
authors.initials: S
authors.lastname: Catheline
mesh_terms: D001921:Brain / Q000502:physiology*; D064368:Healthy Volunteers; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D014732:Vibration
keywords: brain; correlation; elastography