title: Prevalence of celiac disease in adult type 1 patients with diabetes.
abstract: OBJECTIVE
  Celiac disease, an autoimmune disease, is related to immune mediated intolerance to gluten. Some studies suggest that Celiac Disease was 20 times more frequent in type 1 patients with diabetes. The objective of our study was to evaluate the prevalence of celiac disease in hospital based type 1 diabetic adults.
  
  
  METHODS
  Our study was carried out retrospectively in Medeniyet University Goztepe Training and Educational Hospital in Istanbul between 2012-2013. The cohort comprised 482 type 1 patients with diabetes attending the diabetes outpatient clinic. The data were analyzed by SPSS 10.5 package program. Student's t tests is used for comparative analyses. A p-value less than 0.05 was considered statistically significant.
  
  
  RESULTS
  The cohort included 482 type 1 patients with diabetes. Fifty seven of them were not evaluated for Endomysium antibody positivity. Fifteen of the remaining 425 patients were positive for anti endomysial antibody (3.5%). The prevalence of biopsy proven celiac disease was 2.3% (10/425). There was no significant difference between Endomysial antibody positive and negative groups in regard of age, sex, or duration of the disease.
  
  
  CONCLUSIONS
  This study confirms that the celiac disease is common in type 1 diabetic patients. Since a small proportion of celiac patients are symptomatic this disorder should be screened in all adult type 1 patients with diabetes by antiendomysium antibody.
authors.affiliation: Burcu Dogan, Department of Family Medicine, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul Turkey.
authors.forename: Burcu
authors.initials: B
authors.lastname: Dogan
authors.affiliation: Can Oner, Istanbul Bilim University, School of Medicine, Department of Family Medicine, Istanbul Turkey.
authors.forename: Can
authors.initials: C
authors.lastname: Oner
authors.affiliation: Oya Uygur Bayramicli, Private office, Istanbul Turkey.
authors.forename: Oya Uygur
authors.initials: OU
authors.lastname: Bayramicli
authors.affiliation: Elif Yorulmaz, Istanbul Bagcılar Traning and Research Hospital, Department of Gastroenterology, Istanbul Turkey.
authors.forename: Elif
authors.initials: E
authors.lastname: Yorulmaz
authors.affiliation: Guneş Feyizoglu, Department of Internal Medicine, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul Turkey.
authors.forename: Guneş
authors.initials: G
authors.lastname: Feyizoglu
authors.affiliation: Aytekin Oguz, Department of Internal Medicine, Scholl of Medicine, Istanbul Medeniyet University, Istanbul Turkey.
authors.forename: Aytekin
authors.initials: A
authors.lastname: Oguz
keywords: Celiac disease; Prevalence; Type 1 diabetes