title: [EXPERIENCE OF APPLICATION OF THE GENE INDUCTOR OF VASCULAR ENDOTHELIUM GROWTH FACTOR IN TREATMENT OF PATIENTS, SUFFERING ATHEROSCLEROTIC ISCHEMIA OF THE LOWER EXTREMITIES TISSUES].
abstract: The results of examination of patients, suffering chronic ischemia of the lower extremities (LE) stages IIB - III (according to Fontaine), in whom preparation Neovasculgen was used in complex of medicinal therapy, were presented. In terms of follow-up before 12 months the distance, which the patients passed before the pain occurrence, have enhanced by 92.2%, and the ankle-brachial index--by 30.9%. Complications while application of the preparation were absent. Due to the treatment conducted there were LE saved and the patients' quality of life improved.
authors.forename: P I
authors.initials: PI
authors.lastname: Nikulnikov
mesh_terms: D043925:Angiogenesis Inducing Agents / Q000627:therapeutic use*; D055109:Ankle Brachial Index; D050197:Atherosclerosis / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D004730:Endothelium, Vascular / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D015870:Gene Expression / Q000187:drug effects; D006801:Humans; D007273:Injections, Intramuscular; D007511:Ischemia / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D035002:Lower Extremity / Q000098:blood supply / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D018919:Neovascularization, Physiologic / Q000187:drug effects; D010146:Pain / Q000517:prevention & control; D011788:Quality of Life; D016896:Treatment Outcome; D042461:Vascular Endothelial Growth Factor A / Q000819:agonists* / Q000235:genetics / Q000378:metabolism; D016138:Walking
chemical_list: D043925:Angiogenesis Inducing Agents; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A