title: Primary testicular lymphoma: a single centre experience.
abstract: OBJECTIVE
  Primary testicular lymphoma (PTL) is an uncommon and aggressive form of extranodal non-Hodgkin's lymphoma (NHL). We aimed to analyse the clinicopathological characteristics and outcomes of our PTL cases.
  
  
  METHODS
  A review was made of the medical records of 339 NHL patients who were treated in the Medical Oncology Department between January 2005 and December 2013.
  
  
  RESULTS
  8 PTL patients were identified from the 339 NHL patients. The average age of the patients was 67.7 ± 7.9 years (range 53-79 years). The mean follow-up time was 24.8 months (range 7-98 months). Inguinal orchiectomy was performed as a diagnostic and initial therapy and all the patients underwent 4-6 cycles of chemoimmunotherapy consisting of cyclophosphamide, doxorubicin, vincristine and prednisone plus rituximab. 4 of 8 patients received intrathecal prophylactic chemotherapy and 6 of 8 patients continued contralateral testis irradiation. Relapse occured in only 1 patient in central nervous system after 6 months who had not received intrathecal prophylaxis. No contralateral testis relapse was observed.
  
  
  CONCLUSIONS
  Primary testicular NHL is an uncommon entity and we evaluated 8 patients; with one relapse in central nervous system and no relapse in the contralateral testis.
authors.affiliation: Department of Medical Oncology, Faculty of Medicine, Ondokuz Mayis University, Samsun 55139, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Kemal
authors.affiliation: Department of Medical Oncology, Faculty of Medicine, 19 Mayis University, Samsun 55139, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Teker
authors.affiliation: Department of Medical Oncology, Faculty of Medicine, 19 Mayis University, Samsun 55139, Turkey.
authors.forename: G
authors.initials: G
authors.lastname: Demirag
authors.affiliation: Department of Medical Oncology, Faculty of Medicine, 19 Mayis University, Samsun 55139, Turkey.
authors.forename: I
authors.initials: I
authors.lastname: Yucel
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D016896:Treatment Outcome