title: Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal.
abstract: BACKGROUND
  Diabetes ketoacidoisis (DKA) is characterized by hyperketonaemia, metabolic acidosis, and hyperglycemia.
  
  
  OBJECTIVE
  The aim of this study was to describe the demographic profile, clinical characterstics of patients admitted with diabetic ketoacidosis in BPKIHS, medical ward.
  
  
  METHODS
  The hospital based descriptive study.
  
  
  METHODS
  We took all the patients admitted with a diagnosis of diabetic ketoacidosis (DKA) as defined ADA 2006 consensus statement in medical ward from January 2010 to December 2010. The statistical operations was done through Manufactured by IBM Corp.
  
  
  RESULTS
  Only sixteen patients (7 type 1 and 9 type 2DM) were with DKA. When compared to the 16 subjects with type 1 DM, the type 2 were older (56.8 s 25.7 years) and had a significantly higher PH levels (7.11 s 7.28 P = 0.04). The mean body mass index was 20.5±2.44 in both Type 1 and type 2 DM. Four were on diet control and Insulin respectively. Five were on oral hypoglycemic agents (OHA) and three on both (insulin and OHA). Infection was most common precipitating factor (56.25%) followed by poor drug compliance (37.5%) and first presentation (6.25%).
  
  
  CONCLUSIONS
  We found majority of patients were type 2 DM. Metabolic acidosis has significant association in both type of diabetic. We found infection was the most common precipitating factor for DKA.
authors.affiliation: Department of Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
authors.forename: Robin
authors.initials: R
authors.lastname: Maskey
authors.affiliation: Department of Psychiarty, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
authors.forename: Dhana Ratna
authors.initials: DR
authors.lastname: Shakya
authors.affiliation: Department of Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
authors.forename: Bista
authors.initials: B
authors.lastname: Nikesh
authors.affiliation: Department of Internal Medicine, UCMS, Bhairawaha, Nepal.
authors.forename: Kumar Agrawal
authors.initials: KA
authors.lastname: Krishna
authors.affiliation: Department of Ophthalmology, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
authors.forename: Poonam
authors.initials: P
authors.lastname: Lavaju
authors.affiliation: Department of Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
authors.forename: Vivek
authors.initials: V
authors.lastname: Kattel
authors.affiliation: Department of Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
authors.forename: Lubina
authors.initials: L
authors.lastname: Arjyal
authors.affiliation: Department of Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
authors.forename: Prahlad
authors.initials: P
authors.lastname: Karki
keywords: B. P. Koirala Institute of Health Sciences; Dharan; diabetes; ketoacidosis