title: Electrochemical Imprinted Polycrystalline Nickel-Nickel Oxide Half-Nanotube-Modified Boron-Doped Diamond Electrode for the Detection of L-Serine.
abstract: This paper presents a novel and versatile method for the fabrication of half nanotubes (HNTs) using a flexible template-based nanofabrication method denoted as electrochemical imprinting. With use of this method, polycrystalline nickel and nickel(II) oxide (Ni-NiO) HNTs were synthesized using pulsed electrodeposition to transfer Ni, deposited by radio frequency magnetron sputtering on a porous polytetrafluoroethylene template, onto a boron-doped diamond (BDD) film. The Ni-NiO HNTs exhibited semicircular profiles along their entire lengths, with outer diameters of 50-120 nm and inner diameters of 20-50 nm. The HNT walls were formed of Ni and NiO nanoparticles. A biosensor for the detection of L-serine was fabricated using a BDD electrode modified with Ni-NiO HNTs, and the device demonstrated satisfactory analytical performance with high sensitivity (0.33 μA μM(-1)) and a low limit of detection (0.1 μM). The biosensor also exhibited very good reproducibility and stability, as well as a high anti-interference ability against amino acids such as L-leucine, L-tryptophan, L-cysteine, L-phenylalanine, L-arginine, and L-lysine.
authors.affiliation: School of Precision Instrument and Optoelectronics Engineering, Tianjin University , Tianjin 300072, P.R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Dai
authors.forename: Hongji
authors.initials: H
authors.lastname: Li
authors.forename: Mingji
authors.initials: M
authors.lastname: Li
authors.forename: Cuiping
authors.initials: C
authors.lastname: Li
authors.forename: Xiaoguo
authors.initials: X
authors.lastname: Wu
authors.forename: Baohe
authors.initials: B
authors.lastname: Yang
mesh_terms: D001895:Boron / Q000737:chemistry*; D003460:Crystallization; D018130:Diamond / Q000737:chemistry*; D058266:Dielectric Spectroscopy; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D054802:Molecular Imprinting; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D009532:Nickel / Q000737:chemistry*; D012694:Serine / Q000032:analysis*
chemical_list: D012694:Serine; D018130:Diamond; D009532:Nickel; C028007:nickel monoxide; D001895:Boron
keywords: L-serine; biosensor; boron-doped diamond; nickel half-nanotubes; pulse electrochemical deposition