title: Glucose and Insulin Tolerance Tests in the Mouse.
abstract: In vivo metabolic tests are highly valuable to determine whether atherosclerosis progression in mouse models is accompanied by carbohydrate metabolism alterations such as glucose intolerance and insulin resistance. In this chapter, we describe protocols to perform in the mouse glucose and insulin tolerance tests, two metabolic assays which evaluate the glucose tolerance and the insulin sensitivity, respectively.
authors.affiliation: Institute of Health Research-INCLIVA, C/Menéndez Pelayo, 4, 46010, Valencia, Spain.
authors.forename: Ángela
authors.initials: Á
authors.lastname: Vinué
authors.affiliation: Institute of Health Research-INCLIVA, C/Menéndez Pelayo, 4, 46010, Valencia, Spain. gonzaleh@uv.es.
authors.forename: Herminia
authors.initials: H
authors.lastname: González-Navarro
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism*; D004195:Disease Models, Animal; D018450:Disease Progression; D005260:Female; D018149:Glucose Intolerance / Q000097:blood / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D005951:Glucose Tolerance Test / Q000379:methods*; D007328:Insulin / Q000097:blood*; D007333:Insulin Resistance; D008297:Male; D051379:Mice; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D013997:Time Factors
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D007328:Insulin
keywords: Glucose; Insulin; Intraperitoneal injection; Metabolic test; Metabolism