title: New aspects of the clinicopathological features and treatment of mycosis fungoides and Sézary syndrome.
abstract: Mycosis fungoides and Sézary syndrome are T-helper (Th)2-skewed cutaneous lymphomas. The clinical course of mycosis fungoides is classically indolent, manifesting as patches, plaques and tumors. Along with their progression, Th2 dominance tends to be accelerated. In this review, we discuss the epidemiology, clinicopathogenetic features and therapeutic approaches in mycosis fungoides and Sézary syndrome.
authors.affiliation: Department of Dermatology, Kyushu University, Fukuoka, Japan.
authors.forename: Masutaka
authors.initials: M
authors.lastname: Furue
authors.affiliation: Department of Dermatology, St Marianna University School of Medicine, Kanagawa, Japan.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Kadono
mesh_terms: D006801:Humans; D009182:Mycosis Fungoides / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D012751:Sezary Syndrome / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D012867:Skin / Q000473:pathology
keywords: Sézary syndrome; chemokine; mycosis fungoides; pathogenesis; treatment