title: Characteristics of Hospitalized Cases of Pertussis in Catalonia and Navarra, Two Regions in the North of Spain.
abstract: Pertussis causes a large number of cases and hospitalizations in Catalonia and Navarra. We made a study of household cases of pertussis during 2012 and 2013 in order to identify risk factors for hospitalization in pertussis cases. Each primary case reported triggered the study of their contacts. Close contacts at home and people who were in contact for >2 hours during the transmission period of cases were included. The adjusted OR and 95% confidence intervals (CI) was calculated using logistic regression. A total of 1124 pertussis cases were detected, of which 14.9% were hospitalized. Inspiratory whoop (aOR: 1.64; CI: 1.02-2.65), apnoea (aOR: 2.47; CI: 1.51-4.03) and cyanosis (aOR: 15.51; CI: 1.87-128.09) were more common in hospitalized than in outpatient cases. Hospitalization occurred in 8.7% of correctly-vaccinated cases, 41.1% of non-vaccinated cases and 9.4% of partially-vaccinated cases. In conclusion, inspiratory whoop, apnoea and cyanosis were associated factors to hospitalization while vaccination reduced hospitalizations due to pertussis.
authors.affiliation: CIBER Epidemiology and Public Health. Barcelona, Spain; Public Health Department, University of Barcelona, Barcelona, Spain.
authors.forename: Inma
authors.initials: I
authors.lastname: Crespo
authors.affiliation: Public Health Department, University of Barcelona, Barcelona, Spain; Public Health Agency, Barcelona, Spain.
authors.forename: Diana
authors.initials: D
authors.lastname: Toledo
authors.affiliation: CIBER Epidemiology and Public Health. Barcelona, Spain; Public Health Department, University of Barcelona, Barcelona, Spain.
authors.forename: Núria
authors.initials: N
authors.lastname: Soldevila
authors.affiliation: Paediatric Intensive Care Medicine, Hospital Sant Joan de Déu, Barcelona, Spain.
authors.forename: Iolanda
authors.initials: I
authors.lastname: Jordán
authors.affiliation: CIBER Epidemiology and Public Health. Barcelona, Spain; Public Health Department, University of Barcelona, Barcelona, Spain; Public Health Agency, Barcelona, Spain.
authors.forename: Rubén
authors.initials: R
authors.lastname: Solano
authors.affiliation: CIBER Epidemiology and Public Health. Barcelona, Spain; Public Health Institute, Navarra Institute for Health Research, Pamplona, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Castilla
authors.affiliation: CIBER Epidemiology and Public Health. Barcelona, Spain; Public Health Agency, Barcelona, Spain.
authors.forename: Joan A
authors.initials: JA
authors.lastname: Caylà
authors.affiliation: CIBER Epidemiology and Public Health. Barcelona, Spain; Agency of Public Health of Catalonia, Barcelona, Spain.
authors.forename: Pere
authors.initials: P
authors.lastname: Godoy
authors.affiliation: Molecular Microbiology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Muñoz-Almagro
authors.affiliation: CIBER Epidemiology and Public Health. Barcelona, Spain; Public Health Department, University of Barcelona, Barcelona, Spain.
authors.forename: Ángela
authors.initials: Á
authors.lastname: Domínguez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001049:Apnea / Q000209:etiology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003490:Cyanosis / Q000209:etiology / Q000628:therapy*; D005260:Female; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010567:Pertussis Vaccine; D012307:Risk Factors; D013030:Spain; D014917:Whooping Cough / Q000150:complications / Q000517:prevention & control / Q000628:therapy*; D055815:Young Adult
chemical_list: D010567:Pertussis Vaccine