title: Cognitive control during sentence generation.
abstract: Sentence generation involves selecting the right words out of multiple co-activated representations for the right utterance positions. This selection process is hypothesized to involve cognitive control. Previous research has linked cognitive control during language processing to regions within the frontal lobe, including the anterior cingulate cortex (ACC) and left ventrolateral prefrontal cortex (VLPFC). We examined the neural correlates of word and sentence generation to determine whether these cognitive control regions were activated more for sentences than words. We also manipulated the phonological overlap between nouns in the sentence to determine whether cognitive control recruitment increased under phonological competition. Whole-brain analysis revealed increased activation in the ACC and bilateral frontal cortex for sentences over words. Region of interest analysis revealed an effect of phonological competition within the ACC. Psychophysiological interaction (PPI) analysis further showed that functional connectivity within a task-maintenance network increased under phonological competition. These results suggest a role for conflict detection and monitoring during sentence generation, which is consistent with a theoretical framework incorporating domain-general cognitive control processes into language processing.
authors.affiliation: a Department of Speech and Hearing Science , The George Washington University , Washington , DC , USA.
authors.forename: Malathi
authors.initials: M
authors.lastname: Thothathiri
authors.affiliation: a Department of Speech and Hearing Science , The George Washington University , Washington , DC , USA.
authors.forename: Michelle
authors.initials: M
authors.lastname: Rattinger
authors.affiliation: a Department of Speech and Hearing Science , The George Washington University , Washington , DC , USA.
authors.forename: Bhairvi
authors.initials: B
authors.lastname: Trivedi
mesh_terms: D000328:Adult; D001931:Brain Mapping / Q000379:methods*; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006179:Gyrus Cinguli / Q000502:physiology*; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D010700:Phonetics; D017397:Prefrontal Cortex / Q000502:physiology*; D013060:Speech / Q000502:physiology*; D055815:Young Adult
keywords: Sentence generation; anterior cingulate cortex; cognitive control; fmri; phonology; prefrontal cortex