title: Correlation between Six Minute Walk Test and Spirometry in Chronic Pulmonary Disease.
abstract: BACKGROUND
  Six minute walk test (6MWT), is an exercise test, used as a clinical indicator of the functional capacity, in patients with cardiopulmonary diseases. The present study assessed the correlation of six minute walk test with pulmonary function variables, in patients with chronic pulmonary diseases, in local population.
  
  
  OBJECTIVE
  The objectives were to study correlation of different spirometry variables with variables of six minute walk test like percent predicted 6 minute walk distance (% Predicted 6MWD) as per Enright et al., formula and Indian reference equation, pre and post exercise pO2 and pCO2 and exercise desaturation.
  
  
  METHODS
  All consecutive patients with confirmed diagnosis of chronic pulmonary diseases were included from January 2013 to June 2014 in tertiary care institute. 6MWT was performed as per the ATS guidelines. Among 130 patients 108 were also subjected to arterial blood gases pre and post test. Spirometry was performed as per ATS guidelines. Percent (%) predicted 6MWD was calculated. Correlation between spirometry and 6MWT was assessed.
  
  
  RESULTS
  One hundred and thirty patients with chronic pulmonary disease were taken. Out of them there was 102 patients with obstructive airway disease and 58 patients with interstitial lung disease. FEV1 significantly correlated with %predicted 6MWD &; with basal pO2 and pCO2 and with post exercise pCO2 and pO2. FVC also correlated with %predicted 6MWD, with basal pO2 and pCO2 and post exercise pO2. FEV1/FVC correlated only with post exercise pCO2 while MVV correlated with %predicted 6MWD and only basal pCO2. Exercise desaturation correlated only with FVC. Percent predicted 6MWD also correlated with basal pO2 & post exercise pO2.
  
  
  CONCLUSIONS
  Thus significant correlation found between 6MWT & spirometry variables (FEV1, FVC, MVV & FEV1/FVC).
authors.affiliation: Resident, Department of Pulmonary Medicine, Lokmanya Tilak Municipal Medical College and General Hospital , Mumbai, India .
authors.forename: Mitali Bharat
authors.initials: MB
authors.lastname: Agrawal
authors.affiliation: Professor and Head, Department of Pulmonary Medicine, Lokmanya Tilak Municipal Medical College and General Hospital , Mumbai, India .
authors.forename: Nilkanth Tukaram
authors.initials: NT
authors.lastname: Awad
keywords: Interstitial lung diseases; Obstructive airway diseases; Spirometry