title: Establishment of an Ebola Treatment Unit and Laboratory - Bombali District, Sierra Leone, July 2014-January 2015.
abstract: The first confirmed case of Ebola virus disease (Ebola) in Sierra Leone related to the ongoing epidemic in West Africa occurred in May 2014, and the outbreak quickly spread. To date, 8,704 Ebola cases and 3,955 Ebola deaths have been confirmed in Sierra Leone. The first Ebola treatment units (ETUs) in Sierra Leone were established in the eastern districts of Kenema and Kailahun, where the first Ebola cases were detected, and these districts were also the first to control the epidemic. By September and October 2014, districts in the western and northern provinces, including Bombali, had the highest case counts, but additional ETUs outside of the eastern province were not operational for weeks to months. Bombali became one of the most heavily affected districts in Sierra Leone, with 873 confirmed patients with Ebola during July-November 2014. The first ETU and laboratory in Bombali District were established in late November and early December 2014, respectively. T- evaluate the impact of the first ETU and laboratory becoming operational in Bombali on outbreak control, the Bombali Ebola surveillance team assessed epidemiologic indicators before and after the establishment of the first ETU and laboratory in Bombali. After the establishment of the ETU and laboratory, the interval from symptom onset to laboratory result and from specimen collection to laboratory result decreased. By providing treatment to Ebola patients and isolating contagious persons to halt ongoing community transmission, ETUs play a critical role in breaking chains of transmission and preventing uncontrolled spread of Ebola (4). Prioritizing and expediting the establishment of an ETU and laboratory by pre-positioning resources needed to provide capacity for isolation, testing, and treatment of Ebola are essential aspects of pre-outbreak planning.
authors.forename: Brigette
authors.initials: B
authors.lastname: Gleason
authors.forename: John
authors.initials: J
authors.lastname: Redd
authors.forename: Peter
authors.initials: P
authors.lastname: Kilmarx
authors.forename: Tom
authors.initials: T
authors.lastname: Sesay
authors.forename: Francis
authors.initials: F
authors.lastname: Bayor
authors.forename: Antons
authors.initials: A
authors.lastname: Mozalevskis
authors.forename: Allison
authors.initials: A
authors.lastname: Connolly
authors.forename: James
authors.initials: J
authors.lastname: Akpablie
authors.forename: Dimitri
authors.initials: D
authors.lastname: Prybylski
authors.forename: Daphne
authors.initials: D
authors.lastname: Moffett
authors.forename: Michael
authors.initials: M
authors.lastname: King
authors.forename: Micah
authors.initials: M
authors.lastname: Bass
authors.forename: Kristy
authors.initials: K
authors.lastname: Joseph
authors.forename: Jefferson
authors.initials: J
authors.lastname: Jones
authors.forename: Francis
authors.initials: F
authors.lastname: Ocen
mesh_terms: D004196:Disease Outbreaks / Q000517:prevention & control*; D029043:Ebolavirus / Q000302:isolation & purification; D058872:Epidemics / Q000517:prevention & control; D058016:Health Facility Administration; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D007753:Laboratories / Q000458:organization & administration*; D012807:Sierra Leone / Q000453:epidemiology