title: [Relationship between central obesity and clustering of cardiovascular risk factors in adults of Jiangsu province].
abstract: OBJECTIVE
  To explore the relationship between central obesity and cardiovascular risk factors and their clustering in adults of Jiangsu province.
  
  
  METHODS
  Multi-stratified clustering sampling method was used to sample 8 400 residents aged 18 years and over from 14 diseases surveillance units in Jiangsu province from October to December 2010. Information was obtained with face-to-face interview, physical examination and laboratory testing. A total of 8 380 residents finished the study protocol and their data were analyzed. Central obesity was defined as waist circumference ≥ 85 cm in males or ≥ 80 cm in females. Following complex weighting of the samples, level and proportion of cardiovascular risk factors in group with different waist circumference were analyzed.
  
  
  RESULTS
  The prevalence of central obesity among adults in Jiangsu province was 46.2%, the proportion of males and females was 46.4% and 46.1%, respectively (P > 0.05). The prevalence of center obesity varied significantly in residents with different age, area, education and occupation (all P < 0.01). The level of systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, triglyceride, high density lipoprotein cholesterol and low density lipoprotein cholesterol was also significantly different in residents with different degree of waist circumference (all P < 0.01). The prevalence of hypertension, diabetes, dyslipidemia and clustering of cardiovascular risk factors increased in proportion to increasing waist circumference (all P < 0.05). Multivariate logistic regression analysis showed that the risk of hypertension, diabetes, dyslipidemia and clustering of cardiovascular risk factors was 2.2 (OR = 2.2, 95% CI: 2.0-2.4) and 4.7 (OR = 4.7, 95% CI: 3.9-5.7); 2.1 (OR = 2.1, 95% CI: 1.7-2.5) and 3.8 (OR = 3.8, 95% CI: 3.2-4.5); 2.3 (OR = 2.3, 95% CI: 1.8-2.9) and 4.1 (OR = 4.1, 95% CI: 3.2-5.3); 3.4 (OR = 3.4, 95% CI: 2.9-3.9) and 8.0 (OR = 8.0, 95% CI: 6.2-10.2) fold higher in residents with mild and severe central obesity than residents without central obesity.
  
  
  CONCLUSIONS
  The extent of central obesity positively correlates with the prevalence of cardiovascular risk factors and their clustering in adults of Jiangsu province. Comprehensive interventions on obesity serve as an important tool to reduce the cardiovascular risk in adult Jiangshu residents.
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Su
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Quanyong
authors.initials: Q
authors.lastname: Xiang
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Shurong
authors.initials: S
authors.lastname: Lyu
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Xiaoqun
authors.initials: X
authors.lastname: Pan
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Qin
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Jinyi
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Yongqing
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.affiliation: Department of Chronic Non-communicable Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China; Email: trltjy@163.com.
authors.forename: Ran
authors.initials: R
authors.lastname: Tao
mesh_terms: D000328:Adult; D001794:Blood Pressure; D001835:Body Weight; D002318:Cardiovascular Diseases; D002784:Cholesterol; D016000:Cluster Analysis; D003920:Diabetes Mellitus; D050171:Dyslipidemias; D005260:Female; D006801:Humans; D006973:Hypertension; D008297:Male; D009765:Obesity; D056128:Obesity, Abdominal; D010808:Physical Examination; D015995:Prevalence; D012307:Risk Factors; D014280:Triglycerides; D055105:Waist Circumference
chemical_list: D014280:Triglycerides; D002784:Cholesterol