title: KPC-PRODUCING Serratia marcescens IN A HOME-CARE PATIENT FROM RECIFE, BRAZIL.
abstract: In this brief communication we describe the occurrence of a KPC-producing Serratia marcescens isolate in a home-care patient from Recife, Brazil. The blaKPC, blaSPM, blaIMP, blaVIM, blaOXA, blaCTX-M, blaSHV, blaTEM and blaGES genes were investigated by Polymerase Chain Reaction (PCR) and DNA sequencing. The isolate was positive for blaKPC-2 and blaTEM-1 and was resistant to aztreonam, cefepime, cefotaxime, imipenem, meropenem, gentamicin, ciprofloxacin and cefazidime, and susceptible only to amikacin, tigecycline and gatifloxacin. This is the first report in Brazil of KPC-producing S. marcescens clinical isolate outside of a hospital environment. Caregivers should be alert for the presence of this isolate in the community setting.
authors.affiliation: Departamento de Medicina Tropical, Universidade Federal de Pernambuco, Recife, PE, BR.
authors.forename: Emmily
authors.initials: E
authors.lastname: Margate
authors.affiliation: Departamento de Medicina Tropical, Universidade Federal de Pernambuco, Recife, PE, BR.
authors.forename: Vera
authors.initials: V
authors.lastname: Magalhães
authors.affiliation: Universidade Federal de São Paulo, Sâo Paulo, SP, BR.
authors.forename: Lorena Cristina Corrêa
authors.initials: LC
authors.lastname: Fehlberg
authors.affiliation: Universidade Federal de São Paulo, Sâo Paulo, SP, BR.
authors.forename: Ana Cristina
authors.initials: AC
authors.lastname: Gales
authors.affiliation: Departamento de Medicina Tropical, Universidade Federal de Pernambuco, Recife, PE, BR.
authors.forename: Ana Catarina Souza
authors.initials: AC
authors.lastname: Lopes
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil; D016521:Electrophoresis, Gel, Pulsed-Field; D006699:Home Care Services; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D016868:Serratia Infections / Q000382:microbiology*; D012706:Serratia marcescens / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification*; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases