title: Massive hemoperitoneum due to a ruptured corpus luteum cyst in a patient with congenital hypofibrinogenemia.
abstract: Congenital afibrinogenemia/hypofibrinogenemia is a rare inherited hematologic disorder in which a patient lacks or has insufficient level of fibrinogen, the blood coagulation factor I. The incidence of this uncommon disease is 1 to 2 per 1 million individuals. Hence, massive hemoperitoneum caused by ovulation in a woman with congenital afibrogenemia is also a very rare clinical condition. Massive hemoperitoneum usually presents as acute abdominal pain with potential findings of peritonitis including abdominal distention, hypotension and tachycardia with critical consequences. We performed emergent endoscopic surgery for hemoperitoneum caused by a ruptured corpus luteum cyst in a patient with congenital hypofibrinogenemia. To the best of our knowledge, this was the first case report of such treatment in Korea.
authors.affiliation: Department of Obstetrics and Gynecology, Institute for Medical Sciences, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Jong-Hyun
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Institute for Medical Sciences, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: So-Young
authors.initials: SY
authors.lastname: Jeong
authors.affiliation: Department of Obstetrics and Gynecology, Institute for Medical Sciences, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Dong-Hyu
authors.initials: DH
authors.lastname: Cho
keywords: Afibrinogenemia; Hemoperitoneum; Hypofibrinogenemia congenital; Ovarian cysts; Rupture