title: Insights in Nanoparticle-Bacterium Interactions: New Frontiers to Bypass Bacterial Resistance to Antibiotics.
abstract: Nanotechnology has been revealed as a fundamental approach for antibiotics delivery. In this paper, recent findings demonstrating the superiority of nanocarried-antibiotics over "naked" ones and the ways by which nanoparticles can help to overwhelm bacterial drug resistance are reviewed. The second part of this paper sheds light on nanoparticle-bacterium interaction patterns. Finally, key factors affecting the effectiveness of nanoparticles interactions with bacteria are discussed.
authors.forename: Roudayna
authors.initials: R
authors.lastname: Diab
authors.forename: Bahman
authors.initials: B
authors.lastname: Khameneh
authors.forename: Olivier
authors.initials: O
authors.lastname: Joubert
authors.affiliation: SRSMC, UMR 7565, CNRSUniversite de Lorraine, Faculte de Pharmacie, 5, rue Albert Lebrun, BP 80403, 54001 Nancy Cedex, France. roudayna.diab@univ-lorraine.fr.
authors.forename: Raphael
authors.initials: R
authors.lastname: Duval
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D016503:Drug Delivery Systems; D024881:Drug Resistance, Bacterial; D006801:Humans; D053758:Nanoparticles; D036103:Nanotechnology
chemical_list: D000900:Anti-Bacterial Agents