title: Familial adenomatous polyposis in an adolescent with coexisting schizophrenia: treatment strategies and implications.
abstract: Schizophrenia is associated with high mortality and morbidity. The etiology of schizophrenia remains unclear, studies implicate a multifactorial origin with genetic and environmental factors. The adenomatous polyposis coli (APC) gene has been associated with FAP (familial adenomatous polyposis), and studies have linked it to schizophrenia. However, there are few studies which examine the association between FAP and schizophrenia. Limited data exist regarding recommendations for genetic counseling of adolescents with comorbid psychiatric illness. A case of an adolescent with FAP who developed psychotic symptoms is presented. This case hopes to add to the literature about mental illness in those with FAP. A review of literature about the role of APC in schizophrenia as well as implications of genetic counseling on those who suffer with mental illness will be discussed.
authors.affiliation: Bronx Lebanon Hospital Center, Albert Einstein College of Medicine Bronx, New York ; Albert Einstein College of Medicine Bronx, New York.
authors.forename: Luisa
authors.initials: L
authors.lastname: Gonzalez
authors.affiliation: Bronx Lebanon Hospital Center, Albert Einstein College of Medicine Bronx, New York.
authors.forename: Jose
authors.initials: J
authors.lastname: Alvarez
authors.affiliation: Albert Einstein College of Medicine Bronx, New York.
authors.forename: Erica
authors.initials: E
authors.lastname: Weinstein
authors.affiliation: Bronx Lebanon Hospital Center, Albert Einstein College of Medicine Bronx, New York ; Albert Einstein College of Medicine Bronx, New York.
authors.forename: Panagiota
authors.initials: P
authors.lastname: Korenis
keywords: Adolescent; familial adenomatous polyposis; genetic; schizophrenia