title: Temporal Trends in Anesthesia-related Adverse Events in Cesarean Deliveries, New York State, 2003-2012.
abstract: BACKGROUND
  Cesarean delivery (CD) is associated with significantly increased risks of anesthesia-related adverse events (ARAEs) and nonanesthetic perioperative morbidity compared with vaginal delivery. Temporal trends in these adverse outcomes remain unknown despite efforts to improve maternal safety. This study examines temporal trends in ARAEs and nonanesthetic perioperative complications in CDs in New York hospitals.
  
  
  METHODS
  Data are from the State Inpatient Database for New York, 2003-2012. ARAEs, including minor and major ARAEs, and nonanesthetic perioperative complications were identified through International Classification of Diseases, Ninth Revision, Clinical Modification codes. Statistical significance in time trends was assessed using the Cochran-Armitage test and multivariable logistic regression.
  
  
  RESULTS
  Of the 785,854 CDs studied, 5,715 (730 per 100,000; 95% CI, 710 to 750) had at least one ARAE and 7,040 had at least one perioperative complication (890 per 100,000; 95% CI, 870 to 920). The overall annual rate of ARAEs decreased from 890 per 100,000 in 2003 to 660 in 2012 (25% decrease; 95% CI, 16 to 34; P < 0.0001). The rate of minor ARAEs decreased 23% (95% CI, 13 to 32) and of major ARAEs decreased 43% (95% CI, 23 to 63). No decrease was observed in the rate of ARAEs for CDs performed under general anesthesia. The rate of nonanesthetic complications increased 47% (95% CI, 31 to 63; P < 0.0001).
  
  
  CONCLUSIONS
  Anesthesia-related outcomes in cesarean deliveries appear to have improved significantly across hospitals in New York in the past decade. Perioperative nonanesthetic complications remain a serious healthcare issue.
authors.affiliation: From the Department of Anesthesiology, Columbia University College of Physicians and Surgeons, New York, New York (J.G., R.L., G.L.); Département d'Anesthésie-Réanimation, APHP, Hôpital Bichat-Claude Bernard, Paris, France (J.G.); INSERM, UMR 1137, IAME, Paris, France (J.G.); Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (C.A.W.); and Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York (G.L.).
authors.forename: Jean
authors.initials: J
authors.lastname: Guglielminotti
authors.forename: Cynthia A
authors.initials: CA
authors.lastname: Wong
authors.forename: Ruth
authors.initials: R
authors.lastname: Landau
authors.forename: Guohua
authors.initials: G
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000758:Anesthesia / Q000009:adverse effects* / Q000639:trends*; D002585:Cesarean Section / Q000009:adverse effects* / Q000639:trends*; D036861:Delivery, Obstetric / Q000009:adverse effects* / Q000639:trends*; D005260:Female; D006801:Humans; D009518:New York / Q000453:epidemiology; D010351:Patient Discharge / Q000639:trends; D011247:Pregnancy; D013997:Time Factors; D055815:Young Adult