title: Biomarkers: Troponin testing--risk stratification to stratified medicine.
abstract: Among patients with diabetes mellitus and ischaemic heart disease, high-sensitivity testing effectively identified 39.3% of patients with elevated troponin levels who were at high 5-year risk of cardiovascular death, myocardial infarction, or stroke. Compared with optimal medical therapy, revascularization did not reduce ischaemic events among patients with elevated troponin levels.
authors.affiliation: Division of Cardiology, Department of Medicine and the Duke Clinical Research Institute, Duke University Medical Center, P.O. Box 17969, Durham, NC 27715, USA.
authors.forename: L Kristin
authors.initials: LK
authors.lastname: Newby
authors.affiliation: Division of Cardiology, Department of Medicine and the Duke Clinical Research Institute, Duke University Medical Center, P.O. Box 17969, Durham, NC 27715, USA.
authors.forename: E Magnus
authors.initials: EM
authors.lastname: Ohman
mesh_terms: D015415:Biomarkers / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications / Q000628:therapy; D006801:Humans; D017202:Myocardial Ischemia / Q000097:blood* / Q000150:complications / Q000628:therapy; D009204:Myocardial Revascularization; D018570:Risk Assessment / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers