title: [Prevalence of non-alcoholic fatty liver disease in a population with elevated transaminases and level of accuracy of the diagnosis in Primary Care].
abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of elevated transaminases in adults.
  
  
  OBJECTIVE
  Determine the prevalence of NASH in patients with sustained hypertransaminasemia, and Know the adequacy of the registered in Primary Care (AP) diagnosis.
  
  
  METHODS
  1) Cross-sectional study with a random sample of patients with elevated alanine aminotransferase (ALT) held (ALT> 32 for ≥6 months), ruling out other causes of liver disease, according to clinical, laboratory and ultrasound scan criteria in AP and 2) cross-sectional description of all cases diagnosed with NASH recorded (K76 - ICD10) with diagnostic adequacy analysis according to standard criteria.
  
  
  RESULTS
  290 patients were analyzed: 76 were diagnosed as NASH (26.1%), 44 women (57.9%). Multivariate analysis adjusted for age and sex showed no association between NASH and male gender (OR: 0.5; CI95%: 0.3-0.9), diabetes mellitus (DM) (OR: 2.42; CI95%: 1.2-4.9) and hypertension blood pressure (HBP) (OR: 3.07; CI 95% 1.6-5.6). Of the 209 diagnosed with NASH record: 51 (24.4%) met the criteria for NASH. The rest had insufficient records.
  
  
  CONCLUSIONS
  53.1% lacked sustained hypertransaminasemia; 48% of viral serology; 11% supported and 53.1% abdominal ultrasound registration of alcohol.
  
  
  CONCLUSIONS
  Severe NASH is frequent among patients with sustained hypertransaminasemia. The DM and hypertension significantly increase the risk of NASH. The diagnosis of NASH is recorded without considering all criteria and mainly NASH made by ultrasonography. They should unify diagnostic criteria in the register of NASH.
authors.affiliation: Centro de Atención Primaria Horta 7F, Institut Català de la Salut, Barcelona, España.
authors.forename: María Amelia
authors.initials: MA
authors.lastname: Samperio-González
authors.affiliation: Centro de Atención Primaria Horta 7D, Institut Català de la Salut, Barcelona, España.
authors.forename: Marta
authors.initials: M
authors.lastname: Selvi-Blasco
authors.affiliation: Centro de Atención Primaria Horta 7F, Institut Català de la Salut, Barcelona, España.
authors.forename: Mónica
authors.initials: M
authors.lastname: Manzano-Montero
authors.affiliation: Centro de Atención Primaria Horta 7F, Institut Català de la Salut, Barcelona, España.
authors.forename: Judit
authors.initials: J
authors.lastname: Méndez-Gómez
authors.affiliation: Hospital de Sabadell, Corporació Sanitaria Parc Taulí, Sabadell, Barcelona, España.
authors.forename: Montserrat
authors.initials: M
authors.lastname: Gil-Prades
authors.affiliation: Centro de Atención Primaria Badia del Vallès, Institut Català de la Salut, GROIMAP de USR MN-IDIAP Jordi Gol, Universitat Autònoma de Barcelona, Barcelona, España. Electronic address: rafael.azagra@uab.cat.
authors.forename: Rafael
authors.initials: R
authors.lastname: Azagra
mesh_terms: D000410:Alanine Transaminase / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease / Q000175:diagnosis* / Q000453:epidemiology*; D015995:Prevalence; D011320:Primary Health Care; D015203:Reproducibility of Results; D012189:Retrospective Studies
chemical_list: D000410:Alanine Transaminase
keywords: Atención primaria; Esteatosis hepática no alcohólica; Hipertransaminasemia; Hypertransaminasemia; Non-alcoholic fatty liver disease; Primary care