title: Mycemycins A-E, New Dibenzoxazepinones Isolated from Two Different Streptomycetes.
abstract: Five new dibenzoxazepinone derivatives, mycemycins A-E (1-5), were isolated from the ethanol extracts of mycelia of two different streptomycetes. 1 and 2 were isolated from an acidic red soil-derived strain, Streptomyces sp. FXJ1.235, and 3-5 from a gntR gene-disrupted deep-sea strain named Streptomyces olivaceus FXJ8.012Δ1741. The structures of mycemycins were elucidated by a combination of spectroscopic analyses, including 1D- and 2D-NMR techniques.
authors.affiliation: State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China. fussliu@126.com.
authors.forename: Ning
authors.initials: N
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China. songfangying_@126.com.|University of Chinese Academy of Sciences, Beijing 100049, China. songfangying_@126.com.
authors.forename: Fangying
authors.initials: F
authors.lastname: Song
authors.affiliation: Analytical and Testing Center, Beijing University of Chemical Technology, Beijing 100029, China. sjynm220@126.com.
authors.forename: Fei
authors.initials: F
authors.lastname: Shang
authors.affiliation: State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China. huangy@im.ac.cn.
authors.forename: Ying
authors.initials: Y
authors.lastname: Huang
mesh_terms: D003989:Dibenzoxazepines / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013045:Species Specificity; D013057:Spectrum Analysis / Q000379:methods; D013302:Streptomyces / Q000737:chemistry* / Q000145:classification
chemical_list: D003989:Dibenzoxazepines
keywords: Streptomyces; deep-sea; dibenzoxazepinone; gene disruption; mycemycin