title: Effect of aerobic training and resistance training on circulating irisin level and their association with change of body composition in overweight/obese adults: a pilot study.
abstract: The novel myokine irisin has been reported as a therapeutic target for metabolic disease. The objective of this study is to reveal the effects of aerobic training (AT) and resistance training (RT) on circulating irisin levels and their associations with change of body composition in overweight/obese adults. Twenty eight overweight/obese adults (BMI>23 kg/m(2)) were included in this study and compared before and after 8 weeks of exercise program (60 min/day, 5 times in a week). The subjects, in both aerobic and resistance training, showed significant improvement in anthropometric parameters and exercise capacities including maximal oxygen uptake and muscle strength. Interestingly, the circulating irisin was significantly increased in resistance training group (p=0.002) but not in aerobic training (p=0.426) compared to control group. In addition, we found the positive correlation between change of the circulating irisin and muscle mass (r=0.432, p=0.022) and the negative correlation between change of the circulating irisin and fat mass (r=-0.407, p=0.031). In the present pilot study, we found that circulating irisin level was increased by 8 weeks of resistance training in overweight/obese adults, suggesting that resistance training could be the efficient exercise type in overweight/obese considering positive change of body composition concomitant with increase of irisin levels.
authors.affiliation: Health and Exercise Science Laboratory, Institute of Sports Science, Seoul National University, Gwank-gu, Seoul, Korea. songw3@snu.ac.kr.
authors.forename: H-J
authors.initials: HJ
authors.lastname: Kim
authors.forename: H-J
authors.initials: HJ
authors.lastname: Lee
authors.forename: B
authors.initials: B
authors.lastname: So
authors.forename: J S
authors.initials: JS
authors.lastname: Son
authors.forename: D
authors.initials: D
authors.lastname: Yoon
authors.forename: W
authors.initials: W
authors.lastname: Song
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001823:Body Composition / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D008297:Male; D009765:Obesity / Q000097:blood / Q000175:diagnosis / Q000628:therapy; D050177:Overweight / Q000097:blood* / Q000175:diagnosis / Q000628:therapy*; D010865:Pilot Projects; D055070:Resistance Training / Q000379:methods; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; C577593:FNDC5 protein, human; D005353:Fibronectins