title: Methylene blue treatment for resistant shock following renal transplantation.
abstract: We report a case of a 19-year-old female with a history of hyperoxaluria type 1 and renal failure. The patient presented for a second renal transplantation 17 years after her first combined liver and kidney transplantation. Postoperative shock was highly resistant to fluids and required massive pharmacologic hemodynamic support. Vasoplegic shock was the presumed diagnosis, and methylene blue was utilized as a rescue therapy, with a rapid hemodynamic response and no apparent side effects.
authors.affiliation: Department of Pediatric Intensive Care, Ruth Rappaport Children's Hospital at Rambam Health Care Campus, Haifa, Israel.
authors.forename: Eli
authors.initials: E
authors.lastname: Hershman
authors.affiliation: Department of Pediatric Intensive Care, Ruth Rappaport Children's Hospital at Rambam Health Care Campus, Haifa, Israel.
authors.forename: Amir
authors.initials: A
authors.lastname: Hadash
authors.affiliation: Department of Pediatric Intensive Care, Ruth Rappaport Children's Hospital at Rambam Health Care Campus, Haifa, Israel.
authors.forename: Ori
authors.initials: O
authors.lastname: Attias
authors.affiliation: Department of Pediatric Intensive Care, Ruth Rappaport Children's Hospital at Rambam Health Care Campus, Haifa, Israel.
authors.forename: Josef
authors.initials: J
authors.lastname: Ben-Ari
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008751:Methylene Blue / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D012769:Shock / Q000188:drug therapy* / Q000209:etiology; D056987:Vasoplegia / Q000150:complications / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D008751:Methylene Blue
keywords: intensive care units; kidney transplantation; methylene blue; pediatric; postoperative care; shock; vasoplegia