title: Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual "Headcheese Pattern" with Nodules.
abstract: A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered.
authors.affiliation: Department of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.|Servizio Pneumologico Territoriale, Azienda Sanitaria dell'Alto Adige, Bolzano, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Pietrangeli
authors.affiliation: Department of Radiology, Ospedale GB Morgagni, Forlì, Italy. piciucchi.sara@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Piciucchi
authors.affiliation: Department of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Tomassetti
authors.affiliation: Department of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Ravaglia
authors.affiliation: Department of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Gurioli
authors.affiliation: Department of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.
authors.forename: Ch
authors.initials: Ch
authors.lastname: Gurioli
authors.affiliation: Department of Pathology, Arcispedale S. Maria Nuova/I.R.C.C.S., Reggio Emilia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cavazza
authors.affiliation: Department of Pathology, Ospedale GB Morgagni, Forlì, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Dubini
authors.affiliation: Department of Diseases of the Thorax, Ospedale GB Morgagni, Forlì, Italy.|Department of Respiratory Diseases & Allergology, Aarhus University Hospital, Aarhus, Denmark.
authors.forename: V
authors.initials: V
authors.lastname: Poletti
mesh_terms: D000368:Aged; D001989:Bronchiolitis Obliterans / Q000150:complications / Q000175:diagnosis*; D003371:Cough / Q000209:etiology; D004417:Dyspnea / Q000209:etiology; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis; D054990:Idiopathic Pulmonary Fibrosis / Q000150:complications / Q000175:diagnosis*; D008168:Lung / Q000000981:diagnostic imaging* / Q000473:pathology; D055613:Multiple Pulmonary Nodules / Q000150:complications / Q000175:diagnosis*; D055099:Neuroendocrine Cells / Q000473:pathology*; D014057:Tomography, X-Ray Computed
keywords: Chromogranin; DIPNECH; Headcheese pattern; UIP pattern