title: Current state and future direction of hybrid coronary revascularization.
abstract: OBJECTIVE
  The most optimal revascularization strategy in patients with multivessel coronary artery disease is a subject of ongoing debate. Hybrid coronary revascularization (HCR) aims to combine the advantages of both percutaneous and surgical revascularization in a single strategy. This review provides a timely overview of the use, practice patterns, clinical outcomes and future perspectives of HCR.
  
  
  RESULTS
  A number of technological advances in stent technology and minimal invasive surgical techniques have enabled the use of HCR, in which the left internal mammary artery is grafted to the left anterior descending artery followed or preceded by percutaneous coronary intervention of non-left anterior descending artery lesions. Currently, HCR is reserved for a highly selected patient population, representing less than 1% of the total coronary artery bypass grafting volume in the United States. Clinical outcomes from observational studies as well as a randomized feasibility trial show encouraging results.
  
  
  CONCLUSIONS
  HCR shows promising clinical results in patients with multivessel disease and/or left main involvement. Engagement from interventional and surgical communities, and adequate patient selection based on local expertise, and data from randomized controlled trials are needed to establish a permanent role in the armamentarium for coronary revascularization.
authors.affiliation: VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Ralf E
authors.initials: RE
authors.lastname: Harskamp
mesh_terms: D003324:Coronary Artery Disease / Q000601:surgery*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000379:methods / Q000639:trends*; D009204:Myocardial Revascularization / Q000639:trends*; D017410:Practice Guidelines as Topic