title: Contralateral recurrence of tumefactive demyelination.
abstract: Tumefactive demyelination refers to large focal demyelinating lesions in the brain, which can be mistaken for malignancy. In some patients, these lesions are monophasic with a self-limited course; however, other patients demonstrate recurrent disease with new tumefactive or non-tumefactive lesions, and a subsequent diagnosis of relapsing-remitting multiple sclerosis is not uncommon. Owing to the limited data available in the literature, many questions about the patterns and prognostic significance of recurrent tumefactive lesions remain unanswered. The current case report involves a patient who recovered from tumefactive demyelination and presented two years later with a new recurrent tumefactive lesion in the contralateral brain.
authors.affiliation: Department of Radiology, University of Manitoba, Winnipeg, Canada nazirkhanmd@gmail.com.
authors.forename: Mohammed Nazir
authors.initials: MN
authors.lastname: Khan
authors.affiliation: Department of Internal Medicine, Section of Neurology, University of Manitoba, Winnipeg, Canada.
authors.forename: Mihail
authors.initials: M
authors.lastname: Guranda
authors.affiliation: Department of Radiology, University of Manitoba, Winnipeg, Canada.
authors.forename: Marco
authors.initials: M
authors.lastname: Essig
mesh_terms: D000328:Adult; D003287:Contrast Media; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000175:diagnosis* / Q000188:drug therapy; D012008:Recurrence; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D005938:Glucocorticoids
keywords: MRI; Tumefactive demyelination; brain; contralateral; multiple sclerosis; neuroinflammation; recurrence; tumefactive multiple sclerosis