title: Extracorporeal Shock Wave Lithotripsy for Chinese Patients With Pancreatic Stones: A Prospective Study of 214 Cases.
abstract: OBJECTIVE
  This study aims to evaluate prospectively the safety and efficacy of extracorporeal shock wave lithotripsy (ESWL) in Chinese patients.
  
  
  METHODS
  A total of 214 patients with painful chronic pancreatitis and pancreatic stones who underwent ESWL followed by endoscopic retrograde cholangiopancreatography from March 2011 to February 2012 in Changhai Hospital were enrolled. The main pancreatic duct clearance rate and complications were recorded prospectively. Symptoms, weight, quality of life, and pancreatic function were assessed before and after ESWL and endotherapy.
  
  
  RESULTS
  A total of 473 ESWL procedures were performed in 214 patients. Stones were fragmented in all cases. Complete clearance of main pancreatic duct stones and successful endoscopic decompression were achieved in 155 (72.4%) and 188 (90.8%) of 214 patients, respectively. Complications were observed after 20 sessions (20 of 473, 4.23%). Follow-up (n = 195) after 18.5 ± 3.3 months showed that complete and partial pain relief were achieved in 71.3% and 24.0% of the patients, respectively. The scores for the quality of life (5.8 ± 1.7 vs 8.1 ± 1.2, P < 0.05) and mental health from the Medical Outcomes Study 36-Item Short-Form General Health Survey questionnaire (62.2 ± 21.5 vs 68.5 ± 16.4, P < 0.05) improved after ESWL.
  
  
  CONCLUSIONS
  Thus, ESWL is a safe and effective method to treat Chinese patients with pancreatic stones. This procedure can significantly improve the success rate of endotherapy.
authors.affiliation: From the *Department of Gastroenterology, †Digestive Endoscopy Center, and ‡Department of Anesthesiology, Changhai Hospital, The Second Military Medical University, Shanghai, China.
authors.forename: Liang-Hao
authors.initials: LH
authors.lastname: Hu
authors.forename: Bo
authors.initials: B
authors.lastname: Ye
authors.forename: Yu-Guang
authors.initials: YG
authors.lastname: Yang
authors.forename: Jun-Tao
authors.initials: JT
authors.lastname: Ji
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Zou
authors.forename: Ting-Ting
authors.initials: TT
authors.lastname: Du
authors.forename: Jun-Feng
authors.initials: JF
authors.lastname: Hao
authors.forename: Ying-Yi
authors.initials: YY
authors.lastname: Jiang
authors.forename: Zhuan
authors.initials: Z
authors.lastname: Liao
authors.forename: Zhao-Shen
authors.initials: ZS
authors.lastname: Li
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000208:Acute Disease; D000328:Adult; D044466:Asian People; D002137:Calculi / Q000150:complications / Q000208:ethnology / Q000628:therapy*; D002681:China; D005260:Female; D005500:Follow-Up Studies; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008096:Lithotripsy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000150:complications / Q000208:ethnology / Q000517:prevention & control*; D010182:Pancreatic Diseases / Q000150:complications / Q000208:ethnology / Q000628:therapy*; D010186:Pancreatic Function Tests; D010195:Pancreatitis / Q000209:etiology; D050500:Pancreatitis, Chronic / Q000150:complications / Q000208:ethnology; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome