title: Dissemination of antibiotic resistance in methicillin-resistant Staphylococcus aureus and vancomycin-resistant S aureus strains isolated from hospital effluents.
abstract: Vancomycin-resistant Staphylococcus aureus (VRSA) and methicillin-resistant S aureus (MRSA) strains were examined in hospital effluents. Most S aureus strains are resistant to methicillin (MRSA), followed by tetracycline. Approximately 15% of MRSA strains are also resistant to vancomycin (VRSA). All VRSA strains developed a VanR/VanS-regulated 2-component system of VanA-type resistance in their genome. Results indicate that there is a possibility of developing resistance to aminoglycosides by VRSA strains in the near future.
authors.affiliation: Department of Microbiology, Vidyasagar University, Midnapore, West Bengal, India. Electronic address: mandalsm@gmail.com.
authors.forename: Santi M
authors.initials: SM
authors.lastname: Mandal
authors.affiliation: Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, India.
authors.forename: Ananta K
authors.initials: AK
authors.lastname: Ghosh
authors.affiliation: Department of Microbiology, Vidyasagar University, Midnapore, West Bengal, India.
authors.forename: Bikas R
authors.initials: BR
authors.lastname: Pati
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D006761:Hospitals; D006801:Humans; D008712:Methicillin / Q000494:pharmacology; D012722:Sewage; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification*; D014640:Vancomycin / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D012722:Sewage; D014640:Vancomycin; D008712:Methicillin
keywords: Antibiogram; Hospital effluents; Methicillin-resistant Staphylococcus aureus; Vancomycin-resistant Staphylococcus aureus