title: Evidence supporting vertical transmission of Salmonella in dairy cattle.
abstract: We set out to investigate whether Salmonella enterica could be recovered from various tissues of viable neonatal calves immediately following parturition. Eleven samples were aseptically collected from each of 20 calves and consisted of both left and right subiliac and prescapular lymph nodes (LN), mesenteric LN, spleen and liver, as well as intestinal tissue (including luminal contents) from the small intestine, caecum, spiral colon and rectum. In addition, a faecal sample was collected from 19 of the dams. Salmonella was recovered from at least one sample from 10 of the 20 neonates. Across all calves, Salmonella was recovered from 12·7% of all samples and from LN in particular, Salmonella was recovered from 10·0%, 5·0%, and 5·0% of subiliac, prescapular, and mesenteric LN, respectively. Within calves, Salmonella was recovered from 0% to 73% of samples and across tissues, estimates of Salmonella prevalence were greatest in the caecum (30%) but was never recovered from the right pre-scapular LN. These data provide evidence of vertical transmission from a dam to her fetus such that viable calves are born already infected and thereby not requiring faecal-oral exposure for transmission. This new knowledge ought to challenge - or at least add to - existing paradigms of Salmonella transmission dynamics within cattle herds.
authors.affiliation: International Center for Food Industry Excellence,Texas Tech University,Lubbock,Texas,USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Hanson
authors.affiliation: International Center for Food Industry Excellence,Texas Tech University,Lubbock,Texas,USA.
authors.forename: G H
authors.initials: GH
authors.lastname: Loneragan
authors.affiliation: United States Department of Agriculture,Agricultural Research Service,Southern Plains Agricultural Research Center,Food and Feed Safety Research Unit,College Station,Texas,USA.
authors.forename: T R
authors.initials: TR
authors.lastname: Brown
authors.affiliation: United States Department of Agriculture,Agricultural Research Service,Southern Plains Agricultural Research Center,Food and Feed Safety Research Unit,College Station,Texas,USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Nisbet
authors.affiliation: United States Department of Agriculture,Agricultural Research Service,Southern Plains Agricultural Research Center,Food and Feed Safety Research Unit,College Station,Texas,USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Hume
authors.affiliation: United States Department of Agriculture,Agricultural Research Service,Southern Plains Agricultural Research Center,Food and Feed Safety Research Unit,College Station,Texas,USA.
authors.forename: T S
authors.initials: TS
authors.lastname: Edrington
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000382:microbiology*; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission*; D005260:Female; D018445:Infectious Disease Transmission, Vertical / Q000662:veterinary*; D012481:Salmonella Infections, Animal / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission*; D019779:Salmonella enterica / Q000302:isolation & purification*; D014481:United States / Q000453:epidemiology
keywords: Epidemiology; Salmonella; zoonoses