title: The Psychological and Medical Factors Associated With Untreated Binge Eating Disorder.
abstract: OBJECTIVE
  Although binge eating disorder (BED) is the most prevalent eating disorder, the impact of untreated BED is underappreciated. This review describes the relationship of BED to physical and mental health, quality of life, and functionality.
  
  
  METHODS
  PubMed searches were conducted on March 21, 2014; searches were limited to English-language research articles, meta-analyses, and reviews published between January 1, 2003 and March 21, 2014. Search terms included (binge eating OR binge-eating OR binge eating disorder) AND (cardiovascular OR metabolic OR metabolic syndrome OR gastrointestinal OR health OR rehabilitation OR recovery OR sleep OR pregnancy OR quality of life OR functional impairment OR activities of daily living OR QoL OR SF-12 OR ED-5D OR SF-36 OR psychosocial OR depressive OR anxiety OR self-esteem OR suicidality OR suicide OR productivity OR family).
  
  
  METHODS
  Of 326 identified publications, 43 were relevant to the topic and reported on the association of BED with psychiatric and medical comorbidities, quality of life, and functional outcomes.
  
  
  RESULTS
  Individuals diagnosed with BED have increased rates of mental health comorbidities (eg, depression and anxiety) and more pronounced medical impairments (eg, cardiovascular disorders) compared with individuals without BED. BED is also associated with functional impairment and reduced quality of life.
  
  
  CONCLUSIONS
  Binge eating disorder is associated with impairments in physical and mental health, which can decrease quality of life and functionality and lead to increased health care utilization and decreased productivity. However, some caution is warranted in interpreting these findings because it remains unclear whether BED is an antecedent condition, a complication associated with a comorbid psychiatric condition, or an unrelated feature that occurs concurrently with these comorbidities and impairments. Much of the research on BED is based on observational or epidemiologic studies. Controlled studies are needed to clearly define the long-term impairments associated with BED.
authors.affiliation: Department of Psychiatry and Behavioral Health, University of South Florida College of Medicine, Tampa (Dr Sheehan), and Shire Development LLC, Wayne, Pennsylvania (Dr Herman).
authors.forename: David V
authors.initials: DV
authors.lastname: Sheehan
authors.affiliation: Department of Psychiatry and Behavioral Health, University of South Florida College of Medicine, Tampa (Dr Sheehan), and Shire Development LLC, Wayne, Pennsylvania (Dr Herman).
authors.forename: Barry K
authors.initials: BK
authors.lastname: Herman