title: Monocyte/HDL-cholesterol ratio predicts the definite stent thrombosis after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.
abstract: OBJECTIVE
  We investigated the predictive value of monocyte count to HDL ratio (M/H ratio) for stent thrombosis (ST) in ST elevation myocardial infarction (STEMI).
  
  
  METHODS
  1170 STEMI patients treated with primary PCI were followed-up for a median of 37.2 months.
  
  
  RESULTS
  During follow-up, 112 patients were diagnosed as 'definite' ST. The rate of ST was significantly highest in the third M/H ratio tertile. In Cox regression analysis, adjusted for other factors, having an M/H ratio in third tertile had a 2.2-fold increased risk of ST. Kaplan-Meier analysis revealed the higher occurrence of ST in the third tertile compared with others (p <0.001).
  
  
  CONCLUSIONS
  M/H ratio as a novel marker of inflammation seemed to be an independent predictor of ST in STEMI patients.
authors.affiliation: Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey.
authors.forename: Elif Hande Ozcan
authors.initials: EH
authors.lastname: Cetin
authors.affiliation: Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey.
authors.forename: Mehmet Serkan
authors.initials: MS
authors.lastname: Cetin
authors.affiliation: Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey.
authors.forename: Uğur
authors.initials: U
authors.lastname: Canpolat
authors.affiliation: Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey.
authors.forename: Selahattin
authors.initials: S
authors.lastname: Aydin
authors.affiliation: Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Topaloglu
authors.affiliation: Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey.
authors.forename: Dursun
authors.initials: D
authors.lastname: Aras
authors.affiliation: Türkiye Yuksek Ihtisas Education & Research Hospital, Cardiology Department, Ankara, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Aydogdu
mesh_terms: D008076:Cholesterol, HDL / Q000097:blood*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000166:cytology*; D009203:Myocardial Infarction / Q000503:physiopathology* / Q000628:therapy; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects*; D011379:Prognosis; D015607:Stents / Q000009:adverse effects*; D013927:Thrombosis / Q000097:blood* / Q000175:diagnosis / Q000209:etiology
chemical_list: D008076:Cholesterol, HDL
keywords: PCI; ST elevation myocardial infarction; inflammation; monocyte to HDL ratio; stent thrombosis