title: Selenium Intake in Hypertensive and Normotensive Post-Menopausal Indonesian Women.
abstract: The Indonesian Ministry of Health has predicted that the national prevalence of hypertension in Indonesia may reach 26.5% in 2013. Increasing age, stress, lack of physical activity, obesity and passive smoking are known to be risk factors of hypertension. In women over 50 y, hormonal changes that occur post-menopause may also increase the risk of hypertension and other vascular diseases. Antioxidant precursors, such as selenium, however, are known to provide protection against the development of several oxidative stress-related diseases, including hypertension. To prove the hypothesis, we compared the levels of consumption of selenium in hypertensive and normotensive post-menopausal women. An observational comparative study with cross-sectional design was conducted in groups of post-menopausal women with hypertension and those who are normotensive. Structured interviews and food recall of 2×24 h were used to determine the level of consumption, and the Depression, Anxiety and Stress Scale (DASS) questionnaire was used to measure the level of stress. The result suggests a significant difference in the levels of selenium intake between the normotensive and hypertensive groups (p=0.008). Furthermore, the passive smoking and stress levels of the hypertensive group were significantly higher than those of the normotensive group. These result support the hypothesis that selenium may play a protective role in vascular disease.
authors.affiliation: Department of Nutrition, School of Public Health, Airlangga University.
authors.forename: Merryana
authors.initials: M
authors.lastname: Adriani
authors.forename: Vella I P
authors.initials: VI
authors.lastname: Diarry
authors.forename: Rizky
authors.initials: R
authors.lastname: Abdulah
authors.forename: Bambang
authors.initials: B
authors.lastname: Wirjatmadi
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage* / Q000032:analysis; D001794:Blood Pressure; D003430:Cross-Sectional Studies; D004032:Diet / Q000009:adverse effects; D004034:Diet Surveys; D004435:Eating; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000523:psychology; D007214:Indonesia / Q000453:epidemiology; D008875:Middle Aged; D010084:Oxidation-Reduction; D017698:Postmenopause / Q000187:drug effects* / Q000523:psychology; D015995:Prevalence; D012307:Risk Factors; D012643:Selenium / Q000008:administration & dosage* / Q000032:analysis; D012907:Smoking / Q000009:adverse effects / Q000523:psychology; D013315:Stress, Psychological / Q000150:complications* / Q000453:epidemiology
chemical_list: D000975:Antioxidants; D012643:Selenium