title: Effect of traditional Chinese comprehensive therapy on gestation in patients with previously failed in vitro fertilization and embryo transfer.
abstract: OBJECTIVE
  To explore the effect of traditional Chinese comprehensive therapy (TCCT) on promoting gestation in patients with previously failed in vitro fertilization and embryo transfer (IVF-ET) because of kidney deficiency, liver stagnation, and blood stasis (KLB).
  
  
  METHODS
  Sixty-seven patients were enrolled in this study and divided into two groups: a trial group with 35 patients and a control group with 32 patients. The trial group was given TCCT for 3 months, then administered IVF-ET or awaited natural pregnancy. The control group was administered IVF--ET without TCCT 3 months after the previous IVF-ET or natural pregnancy attempt. The patterns of KLB were observed both before and after treatment. The natural pregnancy rate of the two groups was calculated after treatment. Differences between the two groups were compared after using IVF-ET treatment again in fertilized egg number and fertilization rate were evaluated.
  
  
  RESULTS
  After treatment with TCM comprehensive therapy, seven patients in the treatment group became pregnant, while there were no successful conceptions in the control group. The difference in clinical pregnancy rate in the initial cycle and transfer cycle of IVF were significantly different (P < 0.05). The trial group had a significantly higher conception rate than that of the control group (P < 0.05).
  
  
  CONCLUSIONS
  TCCT can promote the natural pre nancy rate in patients with previously failed IVF-ET. TCCT could increase patients' fertilized egg number, fertilization rate, pregnancy rate, and clinical pregnancy rate after another IVF-ET treatment.
authors.forename: Xu
authors.initials: X
authors.lastname: Xiaojuan
authors.forename: Jia
authors.initials: J
authors.lastname: Weining
authors.forename: Cheng
authors.initials: C
authors.lastname: Shuhua
authors.forename: Zhong
authors.initials: Z
authors.lastname: Yanmei
authors.forename: Xia
authors.initials: X
authors.lastname: Wanting
authors.lastname: Zeng Qian
mesh_terms: D000328:Adult; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000503:physiopathology; D011247:Pregnancy / Q000187:drug effects*; D018873:Pregnancy Rate
chemical_list: D004365:Drugs, Chinese Herbal