title: Neural circuits underlying motor facilitation during observation of implied motion.
abstract: In the present study we used single and paired-pulse Transcranial Magnetic Stimulation (TMS) to evaluate the effect of implied motion on primary motor cortex microcircuits. We found that observation of the implied motion of a static image increases MEP amplitude and reduces short-interval intracortical inhibition (SICI), without significant modulation of intracortical facilitation and sensory-motor integration. Our results add to the existing literature on the activation of the observation-execution matching system and describe a selective modulation of GABAergic cortical microcircuits during observation of implied motion.
authors.affiliation: a Department of Interprofessional Health Sciences & Health Administration , School of Health and Medical Sciences, Seton Hall University , NJ , USA .
authors.forename: Carmen
authors.initials: C
authors.lastname: Concerto
authors.affiliation: b Pre-clinical sciences, New York College of Podiatric Medicine , New York , USA .
authors.forename: Mohomad
authors.initials: M
authors.lastname: Al Sawah
authors.affiliation: b Pre-clinical sciences, New York College of Podiatric Medicine , New York , USA .
authors.forename: Carmenrita
authors.initials: C
authors.lastname: Infortuna
authors.affiliation: c Department of Art History Columbia University , and Italian Academy for Advanced Studies, Columbia University , New York , USA , and.
authors.forename: David
authors.initials: D
authors.lastname: Freedberg
authors.affiliation: b Pre-clinical sciences, New York College of Podiatric Medicine , New York , USA .
authors.forename: Eileen
authors.initials: E
authors.lastname: Chusid
authors.affiliation: d Department of Clinical and Experimental Medicine , Psychiatry Unit, University of Catania , Italy.
authors.forename: Eugenio
authors.initials: E
authors.lastname: Aguglia
authors.affiliation: a Department of Interprofessional Health Sciences & Health Administration , School of Health and Medical Sciences, Seton Hall University , NJ , USA .
authors.forename: Fortunato
authors.initials: F
authors.lastname: Battaglia
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping; D019054:Evoked Potentials, Motor / Q000502:physiology*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D007092:Imagination; D008297:Male; D009038:Motion; D009044:Motor Cortex / Q000502:physiology*; D009433:Neural Inhibition / Q000502:physiology; D019370:Observation; D050781:Transcranial Magnetic Stimulation
keywords: Implied motion; SICI; sensorymotor integration; transcranial magnetic stimulation