title: Incidental Gallbladder Cancer Visualized From Posttreatment 131I Whole-Body Scan.
abstract: A 72-year-old woman with papillary thyroid cancer post-total thyroidectomy was referred for post-I treatment whole-body scan. Images revealed focal uptake within the gallbladder. Cholecystectomy was subsequently performed, and the pathology report showed well-differentiated adenocarcinoma. Given a history of papillary thyroid cancer, the iodine uptake was reasonably explained as metastasis; however, gallbladder metastasis was extremely infrequent. Literature described the incidental radioiodine retention in the gallbladder as false-positive findings, which can be normal variants or benign hepatobiliary conditions. Primary gallbladder malignancy could be counted for another possibility despite controversial mechanism of uptake.
authors.affiliation: From the Department of Radiology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Yoch
authors.initials: Y
authors.lastname: Anongpornjossakul
authors.forename: Chirawat
authors.initials: C
authors.lastname: Utamakul
authors.forename: Wichana
authors.initials: W
authors.lastname: Chamroonrat
authors.forename: Arpakorn
authors.initials: A
authors.lastname: Kositwattanarerk
authors.forename: Kanungnij
authors.initials: K
authors.lastname: Thamnirat
authors.forename: Chanika
authors.initials: C
authors.lastname: Sritara
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000556:secondary; D000368:Aged; D002277:Carcinoma / Q000473:pathology* / Q000532:radiotherapy; D002291:Carcinoma, Papillary; D005189:False Positive Reactions; D005260:Female; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D006801:Humans; D033162:Incidental Findings; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000532:radiotherapy
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals