title: Enantioselective Synthesis of Substituted δ-Lactones by Cooperative Oxidative N-Heterocyclic Carbene and Lewis Acid Catalysis.
abstract: Efficient construction of complex cylcopentane- or cyclohexane-fused δ-lactones employing redox activation of enals using a chiral N-heterocyclic carbene and LiCl as cooperative catalysts is described. The organocascade proceeds with excellent diastereo- (>99:1) and enantioselectivity (up to >99% ee) and comprises the formation of three bonds with three contiguous stereocenters.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität , Corrensstraße 40, 48149 Münster, Germany.
authors.forename: Srikrishna
authors.initials: S
authors.lastname: Bera
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität , Corrensstraße 40, 48149 Münster, Germany.
authors.forename: Constantin G
authors.initials: CG
authors.lastname: Daniliuc
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität , Corrensstraße 40, 48149 Münster, Germany.
authors.forename: Armido
authors.initials: A
authors.lastname: Studer