title: Drug-induced lupus erythematosus associated with donepezil: a case report.
abstract: The possibility that drug-induced lupus erythematosus (DILE) can be induced by donepezil is presented in this clinical case. Donepezil is an inhibitor of acetylcholinesterase used for the treatment of Alzheimer's disease. It is the first time that donepezil causes DILE.
authors.affiliation: Gerontorheumatologic Outpatient Service, Mariano Lauro Hospital, Naples 80063, Italy.
authors.forename: Ciro
authors.initials: C
authors.lastname: Manzo
authors.affiliation: Alzheimer Evaluation Unit, ASL Napoli Centro, Naples, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Putignano
mesh_terms: D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000188:drug therapy; D000077265:Donepezil; D005260:Female; D006801:Humans; D006867:Hydrolases; D007189:Indans / Q000009:adverse effects* / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000473:pathology; D018697:Nootropic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D010880:Piperidines / Q000009:adverse effects* / Q000627:therapeutic use; D012867:Skin / Q000473:pathology
chemical_list: D007189:Indans; D018697:Nootropic Agents; D010880:Piperidines; D000077265:Donepezil; D006867:Hydrolases; C042472:fluoroacetate-specific dehalogenase
keywords: Alzheimer's disease; donepezil; drug-induced lupus erythematosus; older people