title: Conjunctival Lesions; a Histopathologic Review in Fars Province, Iran.
abstract: OBJECTIVE
  To determine the prevalence of various types of conjunctival lesions, at a tertiary ophthalmic center in Fars Province, South of Iran.
  
  
  METHODS
  Histopathologic slides and medical records of conjunctival lesions submitted to the pathology department of Khalili Hospital, Shiraz, Iran were reviewed from April, 2009 to July, 2013. The histopathologic diagnoses were categorized into benign, pre-malignant, and malignant lesions. The prevalence of various types of conjunctival lesions was calculated.
  
  
  RESULTS
  Histologic sections of 631 conjunctival lesions were reviewed. Benign lesions were most prevalent (81.8%), followed by premalignant (10.8%) and malignant (7.4%) lesions. Pterygia were the most common benign lesions (69.2%), intraepithelial dysplasia constituted most cases of premalignant lesions (94.1%), and squamous cell carcinoma was the most frequent malignant lesion (93.6%). Benign lesions were the most common type of lesions in all age groups, however the prevalence of malignant lesions increased significantly with age (P < 0.001).
  
  
  CONCLUSIONS
  Benign lesions were the most common conjunctival lesions with pterygia on top of the list, while intraepithelial neoplasia and squamous cell carcinoma were the most common premalignant and malignant lesions, respectively. Conjunctival malignant lesions were more prevalent with older age.
authors.affiliation: Department of Ophthalmology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Roshanak
authors.initials: R
authors.lastname: Aliakbar-Navahi
authors.affiliation: Department of Pathology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad Javad
authors.initials: MJ
authors.lastname: Ashraf
authors.affiliation: Department of Pathology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Nosaibe
authors.initials: N
authors.lastname: Seirfar
authors.affiliation: Department of Ophthalmology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Samaneh
authors.initials: S
authors.lastname: Koohestani
authors.affiliation: Department of Pathology, Khalili Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Elham
authors.initials: E
authors.lastname: Abedi
keywords: Conjunctival Lesions; Intraepithelial Dysplasia; Squamous Cell Carcinoma