title: Nucleic-acid recognition interfaces: how the greater ability of RNA duplexes to bend towards the surface influences electrochemical sensor performance.
abstract: The influence of RNA versus DNA on the performance of electrochemical biosensors where redox-labelled nucleic acid duplexes bend towards the electrode surface has been assessed. Faster electron transfer was observed for duplexes containing RNA, suggesting duplexes with RNA are more flexible. These data are of particular importance for microRNA biosensors.
authors.affiliation: School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia. Justin.gooding@unsw.edu.au and Australian Centre for NanoMedicine, The University of New South Wales, Sydney, NSW 2052, Australia.
authors.forename: Roya
authors.initials: R
authors.lastname: Tavallaie
authors.affiliation: School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia. Justin.gooding@unsw.edu.au.
authors.forename: Nadim
authors.initials: N
authors.lastname: Darwish
authors.affiliation: School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia. Justin.gooding@unsw.edu.au.
authors.forename: D Brynn
authors.initials: DB
authors.lastname: Hibbert
authors.affiliation: School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia. Justin.gooding@unsw.edu.au and Australian Centre for NanoMedicine, The University of New South Wales, Sydney, NSW 2052, Australia.
authors.forename: J Justin
authors.initials: JJ
authors.lastname: Gooding
mesh_terms: D015374:Biosensing Techniques / Q000592:standards*; D009696:Nucleic Acids / Q000737:chemistry*; D012313:RNA / Q000737:chemistry*
chemical_list: D009696:Nucleic Acids; D012313:RNA