title: MGDB: a comprehensive database of genes involved in melanoma.
abstract: The Melanoma Gene Database (MGDB) is a manually curated catalog of molecular genetic data relating to genes involved in melanoma. The main purpose of this database is to establish a network of melanoma related genes and to facilitate the mechanistic study of melanoma tumorigenesis. The entries describing the relationships between melanoma and genes in the current release were manually extracted from PubMed abstracts, which contains cumulative to date 527 human melanoma genes (422 protein-coding and 105 non-coding genes). Each melanoma gene was annotated in seven different aspects (General Information, Expression, Methylation, Mutation, Interaction, Pathway and Drug). In addition, manually curated literature references have also been provided to support the inclusion of the gene in MGDB and establish its association with melanoma. MGDB has a user-friendly web interface with multiple browse and search functions. We hoped MGDB will enrich our knowledge about melanoma genetics and serve as a useful complement to the existing public resources. Database URL: http://bioinfo.ahu.edu.cn:8080/Melanoma/index.jsp.
authors.affiliation: Institute of Health Sciences, School of Computer Science and Technology.
authors.forename: Di
authors.initials: D
authors.lastname: Zhang
authors.affiliation: Institute of Health Sciences, School of Computer Science and Technology.
authors.forename: Rongrong
authors.initials: R
authors.lastname: Zhu
authors.affiliation: Institute of Health Sciences, School of Computer Science and Technology.
authors.forename: Hanqian
authors.initials: H
authors.lastname: Zhang
authors.affiliation: College of Electrical Engineering and Automation and Center of Information Support and Assurance Technology, Anhui University, Hefei, Anhui 230601, China.
authors.forename: Chun-Hou
authors.initials: CH
authors.lastname: Zheng
authors.affiliation: Institute of Health Sciences, School of Computer Science and Technology, Center of Information Support and Assurance Technology, Anhui University, Hefei, Anhui 230601, China jfxia@ahu.edu.cn.
authors.forename: Junfeng
authors.initials: J
authors.lastname: Xia
mesh_terms: D030541:Databases, Genetic; D052138:Genes, Neoplasm; D006801:Humans; D008545:Melanoma / Q000235:genetics / Q000378:metabolism; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism; D014584:User-Computer Interface
chemical_list: D009363:Neoplasm Proteins