title: Management of coronary artery disease patients in Latvia compared with practice in Central-Eastern Europe and globally: analysis of the CLARIFY registry.
abstract: OBJECTIVE
  Management of outpatients with stable coronary artery disease (CAD) is important in secondary prevention. The objective was to describe differences in the characteristics of CAD patients in Latvia compared with other countries.
  
  
  METHODS
  CLARIFY is an ongoing international, prospective, observational, longitudinal registry of outpatients with CAD. Data regarding treated outpatients with established CAD from the CLARIFY registry in Latvia (n=120) were compared with those from the rest of Central-Eastern Europe (CEE) (n=2888) and worldwide (n=33,163).
  
  
  RESULTS
  Patients in Latvia had a larger waist circumference (101 [95-109] vs. 99 [91-106] in CEE, 96.5 [88-105]cm worldwide; P=0.023 and P<0.001, respectively) and higher blood pressure (systolic: 138.28±17.13 vs. 133.77±16.47 in CEE and 130.97±16.65mm Hg worldwide, P=0.003 and P<0.001; diastolic: 82.98±8.58 vs. 80.01±9.61 in CEE and 77.22±9.97mm Hg worldwide, P<0.001 and P<0.001, respectively). Body mass index in Latvia did not differ significantly from that in CEE (P=0.422), but was higher than worldwide (28.8 [26.2-32.0] vs. worldwide 27.3 [24.8-30.3]kg/m(2), P<0.001). The history of percutaneous coronary intervention was more frequent in Latvia (74.17% vs. 59.34% in CEE and 58.61% worldwide, P=0.001 and P<0.001, respectively). Latvian patients more frequently used aspirin (97.50% in Latvia vs. 89.75% in CEE and 87.64% worldwide, P=0.005 and P=0.001, respectively).
  
  
  CONCLUSIONS
  Latvian CAD patients are well managed in terms of aspirin use and frequency of percutaneous coronary intervention. Control of obesity and high BP is poorer and needs further improvement.
authors.affiliation: Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, Latvia; Research Institute of Cardiology, University of Latvia, Riga, Latvia; Faculty of Medicine, University of Latvia, Riga, Latvia. Electronic address: a.a.erglis@stradini.lv.
authors.forename: Andrejs
authors.initials: A
authors.lastname: Erglis
authors.affiliation: Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, Latvia; Research Institute of Cardiology, University of Latvia, Riga, Latvia.
authors.forename: Iveta
authors.initials: I
authors.lastname: Mintale
authors.affiliation: Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, Latvia; Research Institute of Cardiology, University of Latvia, Riga, Latvia; Faculty of Medicine, University of Latvia, Riga, Latvia.
authors.forename: Gustavs
authors.initials: G
authors.lastname: Latkovskis
authors.affiliation: Riga Stradins University, Riga, Latvia.
authors.forename: Inga
authors.initials: I
authors.lastname: Balode
authors.affiliation: Latvian Centre of Cardiology, Pauls Stradins Clinical University Hospital, Riga, Latvia; Research Institute of Cardiology, University of Latvia, Riga, Latvia.
authors.forename: Sanda
authors.initials: S
authors.lastname: Jegere
authors.affiliation: Research Institute of Cardiology, University of Latvia, Riga, Latvia.
authors.forename: Iveta
authors.initials: I
authors.lastname: Bajare
authors.affiliation: Research Institute of Cardiology, University of Latvia, Riga, Latvia.
authors.forename: Aldis
authors.initials: A
authors.lastname: Rozenbergs
authors.affiliation: Robertson Centre of Biostatistics, University of Glasgow, Glasgow, United Kingdom.
authors.forename: Nicola
authors.initials: N
authors.lastname: Greenlaw
authors.affiliation: Department of Cardiology and LTTA Centre, University Hospital of Ferrara and Maria Cecilia Hospital, GVM Care & Research, E.S. Health Science Foundation, Cotignola, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Ferrari
authors.affiliation: INSERM U-1148 and University Paris Diderot, Paris, France.
authors.forename: Philippe Gabriel
authors.initials: PG
authors.lastname: Steg
mesh_terms: D000368:Aged; D001241:Aspirin / Q000008:administration & dosage; D015992:Body Mass Index; D003324:Coronary Artery Disease / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D055317:Evidence-Based Practice; D005260:Female; D006801:Humans; D007844:Latvia; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000706:statistics & numerical data; D011446:Prospective Studies; D012042:Registries; D055502:Secondary Prevention; D055105:Waist Circumference
chemical_list: D001241:Aspirin
keywords: Coronary artery disease; Latvia; Prevention; Risk factors