title: Synthetic cannabinoid hyperemesis resulting in rhabdomyolysis and acute renal failure.
abstract: Synthetic cannabinoid usage has increased in the past decade. Concurrently, emergency management of associated adverse effects due to synthetic cannabinoid usage has also risen. Reported toxicities include psychosis, seizures, cardiotoxicity, acute kidney injury, and death. While cannabis was first described as a cause of acute hyperemesis in 2004, a more recent case series also describes the association between cannabinoid hyperemesis and risk of acute renal failure. Synthetic cannabinoids have also been reported to cause acute hyperemesis and acute renal failure; however, the risk of rhabdomyolysis-induced renal failure has yet to be elucidated. In this article, we report the first known case of synthetic cannabinoid hyperemesis leading to rhabdomyolysis and acute renal failure.
authors.affiliation: College of Pharmacy, The University of Texas at Austin, Austin, TX, USA; Pharmacotherapy Education and Research Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: Jacqueline R
authors.initials: JR
authors.lastname: Argamany
authors.affiliation: College of Pharmacy, The University of Texas at Austin, Austin, TX, USA; Pharmacotherapy Education and Research Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: Kelly R
authors.initials: KR
authors.lastname: Reveles
authors.affiliation: College of Pharmacy, The University of Texas at Austin, Austin, TX, USA; Pharmacotherapy Education and Research Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; Pharmacy Department, University Health System, San Antonio, TX, USA. Electronic address: duhon@uthscsa.edu.
authors.forename: Bryson
authors.initials: B
authors.lastname: Duhon
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D002186:Cannabinoids / Q000009:adverse effects*; D006801:Humans; D008297:Male; D002189:Marijuana Abuse / Q000150:complications*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D014839:Vomiting / Q000139:chemically induced*
chemical_list: D002186:Cannabinoids