title: Impact of Chromatin on HIV Replication.
abstract: Chromatin influences Human Immunodeficiency Virus (HIV) integration and replication. This review highlights critical host factors that influence chromatin structure and organization and that also impact HIV integration, transcriptional regulation and latency. Furthermore, recent attempts to target chromatin associated factors to reduce the HIV proviral load are discussed.
authors.affiliation: Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. agosto@bu.edu.
authors.forename: Luis M
authors.initials: LM
authors.lastname: Agosto
authors.affiliation: Graduate Program in Microbiology, Boston University School of Medicine, Boston, MA 02118, USA. patsfan@bu.edu.
authors.forename: Matthew
authors.initials: M
authors.lastname: Gagne
authors.affiliation: Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. andrew.henderson@bmc.org.|Graduate Program in Microbiology, Boston University School of Medicine, Boston, MA 02118, USA. andrew.henderson@bmc.org.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Henderson
keywords: HIV; chromatin; integration; latency; transcription