title: Interface Fluid Syndrome Induced by Uncontrolled Intraocular Pressure Without Triggering Factors After LASIK in a Glaucoma Patient: A Case Report.
abstract: This study sought to describe a glaucoma patient with interface fluid syndrome (IFS) induced by uncontrolled intraocular pressure (IOP) without triggering factors after laser in situ keratomileusis (LASIK). Case report and review of the literature. A 23-year-old man with open-angle glaucoma underwent bilateral LASIK for myopia in 2009. Two years later, the patient reported sudden vision loss. The IOP in the right eye was not measurable using Goldmann applanation tonometry (GAT), but was determined to be 33.7 mm Hg using a noncontact tonometer. IFS was diagnosed based on the presence of space-occupying interface fluid on anterior segment optical coherence tomography images. After a trabeculectomy was performed, the IOP decreased to 10 mm Hg, and GAT measurement became possible. However, the corneal fold remained visible in the flap interface. Six months later, the IOP in the left eye increased, and a trabeculectomy was performed during the early stages of this increase in IOP. Following this procedure, the IOP decreased, and visual acuity remained stable. In glaucoma cases that involve a prior increase in IOP, IOP can continue to increase during the disease course even if temporary control of IOP has been achieved. If LASIK is performed in such cases, the treatment of glaucoma becomes insufficient because of underestimation of the typical IOP. In fact, the measurement of IOP can become difficult because of high-IOP levels. Therefore, LASIK should not be performed on patients with glaucoma who are at high risk of elevated IOP.
authors.affiliation: From the Orthoptics and Visual Science Course (NS), Kitasato University School of Allied Health Sciences; and Department of Ophthalmology (NS, AI, TH, KM, MK, KS), Kitasato University Hospital, Kanagawa, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Shoji
authors.forename: Akira
authors.initials: A
authors.lastname: Ishida
authors.forename: Takahiro
authors.initials: T
authors.lastname: Haruki
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Matsumura
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kasahara
authors.forename: Kimiya
authors.initials: K
authors.lastname: Shimizu
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D000075202:Contraindications; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008297:Male; D009216:Myopia / Q000601:surgery; D013577:Syndrome; D014130:Trabeculectomy; D014786:Vision Disorders / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D055815:Young Adult
chemical_list: D000959:Antihypertensive Agents