title: Androgen secreting giant adrenocortical carcinoma with no metastases: A case report and review of the literature.
abstract: Functional adrenocortical carcinoma (ACC) is a very rare disease with a poor prognosis. Over half (60%) of ACCs bigger than 6 cm synthesize hormones; hormone-secreting ACCs generally include virilization, feminization or Cushing syndrome. Besides, 82% of ACCs are metastatic at the time of diagnosis. While a 48-year-old female patient was examined for abdominal pain and flushing, we detected a non-metastasizing mass (23 × 18 × 16 cm) in the adrenal lodge. The mass was extracted en bloc during open exploration and its histopathology was reported as ACC. We review the literature and report the largest androgen-producing, clinically silent ACC mass cited in the literature so far.
authors.affiliation: Fatih Sultan Mehmet Research and Training Hospital, Department of Urology, Içerenkoy/Atasehir, Istanbul, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Uruc
authors.affiliation: Fatih Sultan Mehmet Research and Training Hospital, Department of Urology, Içerenkoy/Atasehir, Istanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Urkmez
authors.affiliation: Fatih Sultan Mehmet Research and Training Hospital, Department of Urology, Içerenkoy/Atasehir, Istanbul, Turkey.
authors.forename: Ozgur Haki
authors.initials: OH
authors.lastname: Yuksel
authors.affiliation: Fatih Sultan Mehmet Research and Training Hospital, Department of Urology, Içerenkoy/Atasehir, Istanbul, Turkey.
authors.forename: Aytac
authors.initials: A
authors.lastname: Sahin
authors.affiliation: Fatih Sultan Mehmet Research and Training Hospital, Department of Urology, Içerenkoy/Atasehir, Istanbul, Turkey.
authors.forename: Ayhan
authors.initials: A
authors.lastname: Verit