title: Tropheryma whipplei, a Potential Commensal Detected in Individuals Undergoing Routine Colonoscopy.
abstract: Mucosal biopsy samples from individuals not suspected of having Whipple's disease were tested for the presence of Tropheryma whipplei. A sensitive and specific real-time PCR assay targeting a sequence present seven times in the T. whipplei genome was used. T. whipplei DNA was detected in 2.0 and 3.8% of the patients undergoing gastroduodenoscopy and colonoscopy, respectively, who were tested.
authors.affiliation: Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands t.grasman@vumc.nl.
authors.forename: M E
authors.initials: ME
authors.lastname: Grasman
authors.affiliation: Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: A M
authors.initials: AM
authors.lastname: Pettersson
authors.affiliation: Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Catsburg
authors.affiliation: Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: A G
authors.initials: AG
authors.lastname: Koek
authors.affiliation: Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands Department of Internal Medicine, Gastroenterology, and Geriatrics, Zuyderland Medical Center, Heerlen-Sittard-Geleen, The Netherlands.
authors.forename: A A
authors.initials: AA
authors.lastname: van Bodegraven
authors.affiliation: Department of Medical Microbiology and Infection Control, VU University Medical Center, Amsterdam, The Netherlands Department of Medical Microbiology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.
authors.forename: P H M
authors.initials: PH
authors.lastname: Savelkoul
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology*; D003106:Colon / Q000382:microbiology*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D060888:Real-Time Polymerase Chain Reaction; D054851:Tropheryma / Q000302:isolation & purification*