title: Sex Differences in Stroke Subtypes, Severity, Risk Factors, and Outcomes among Elderly Patients with Acute Ischemic Stroke.
abstract: BACKGROUND
  Although the age-specific incidence and mortality of stroke is higher among men, stroke has a greater clinical effect on women. However, the sex differences in stroke among elderly patients are unknown. Therefore, we aimed to assess the sex differences in stroke among elderly stroke patients.
  
  
  METHODS
  Between 2005 and 2013, we recruited 1484 consecutive acute ischemic stroke (AIS) patients (≥75 years old) from a specialized neurology hospital in Tianjin, China. Information regarding their stroke subtypes, severity, risk factors, and outcomes at 3 and 12 months after stroke were recorded.
  
  
  RESULTS
  Comparing with men, women had a significantly higher prevalence of severe stroke (17.20 vs. 12.54%), hypertension (76.42 vs. 66.39%), dyslipidemias (30.35 vs. 22.76%), and obesity (18.40 vs. 9.32%), P < 0.05. Comparing with women, men had a significantly higher prevalence of intracranial artery stenosis (23.11 vs. 17.45%), current smoking (29.60 vs. 13.05%), and alcohol consumption (12.15 vs. 0.47%), P < 0.05. Moreover, dependency was more common among women at 3 and 12 months after stroke, although the sex difference disappeared after adjusting for stroke subtypes, severity, and risk factors.
  
  
  CONCLUSIONS
  Elderly women with AIS had more severe stroke status and worse outcomes at 3 and 12 months after stroke. Thus, elderly female post-AIS patients are a crucial population that should be assisted with controlling their risk factors for stroke and changing their lifestyle.
authors.affiliation: Department of Neurology, Tianjin Huanhu Hospital , Tianjin , China ; Key Laboratory of Cerebral Vascular Disease and Neurodegenerative Disease , Tianjin , China.
authors.forename: Changshen
authors.initials: C
authors.lastname: Yu
authors.affiliation: Department of Neurology, Tianjin Huanhu Hospital , Tianjin , China ; Key Laboratory of Cerebral Vascular Disease and Neurodegenerative Disease , Tianjin , China.
authors.forename: Zhongping
authors.initials: Z
authors.lastname: An
authors.affiliation: Department of Neurology, Tianjin Huanhu Hospital , Tianjin , China ; Key Laboratory of Cerebral Vascular Disease and Neurodegenerative Disease , Tianjin , China.
authors.forename: Wenjuan
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Department of Neurology, Tianjin Huanhu Hospital , Tianjin , China ; Key Laboratory of Cerebral Vascular Disease and Neurodegenerative Disease , Tianjin , China.
authors.forename: Wanjun
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Neurology, Tianjin Huanhu Hospital , Tianjin , China ; Key Laboratory of Cerebral Vascular Disease and Neurodegenerative Disease , Tianjin , China.
authors.forename: Chunlin
authors.initials: C
authors.lastname: Gao
authors.affiliation: Department of Neurology, Tianjin Huanhu Hospital , Tianjin , China ; Key Laboratory of Cerebral Vascular Disease and Neurodegenerative Disease , Tianjin , China.
authors.forename: Shoufeng
authors.initials: S
authors.lastname: Liu
authors.affiliation: Department of Epidemiology, Tianjin Neurological Institute , Tianjin , China.
authors.forename: Jinghua
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Neurology, Tianjin Huanhu Hospital , Tianjin , China ; Key Laboratory of Cerebral Vascular Disease and Neurodegenerative Disease , Tianjin , China.
authors.forename: Jialing
authors.initials: J
authors.lastname: Wu
keywords: elderly; ischemic stroke; outcomes; risk factors; sex differences