title: A Data-Centric Strategy for Modern Biobanking.
abstract: Biobanking has been in existence for many decades and over that time has developed significantly. Biobanking originated from a need to collect, store and make available biological samples for a range of research purposes. It has changed as the understanding of biological processes has increased and new sample handling techniques have been developed to ensure samples were fit-for-purpose.As a result of these developments, modern biobanking is now facing two substantial new challenges. Firstly, new research methods such as next generation sequencing can generate datasets that are at an infinitely greater scale and resolution than previous methods. Secondly, as the understanding of diseases increases researchers require a far richer data set about the donors from which the sample originate.To retain a sample-centric strategy in a research environment that is increasingly dictated by data will place a biobank at a significant disadvantage and even result in the samples collected going unused. As a result biobanking is required to change strategic focus from a sample dominated perspective to a data-centric strategy.
authors.affiliation: School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire, UK. philip.quinlan@nottingham.ac.uk.|School of Computer Science, University of Nottingham, Jubilee Campus, Nottingham, UK. philip.quinlan@nottingham.ac.uk.|Advanced Data Analysis Centre, University of Nottingham, Nottingham, NG7 2RD, UK. philip.quinlan@nottingham.ac.uk.
authors.forename: Philip R
authors.initials: PR
authors.lastname: Quinlan
authors.affiliation: Biolauncher Ltd, Witney Innovation Centre, Witney, OX29 7DX, UK.
authors.forename: Stephen
authors.initials: S
authors.lastname: Gardner
authors.affiliation: Tayside Tissue Bank, HIC Services, Tayside Medical Science Centre, University of Dundee, Dundee, UK.
authors.forename: Martin
authors.initials: M
authors.lastname: Groves
authors.affiliation: School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire, UK.|School of Computer Science, University of Nottingham, Jubilee Campus, Nottingham, UK.
authors.forename: Richard
authors.initials: R
authors.lastname: Emes
authors.affiliation: School of Computer Science, University of Nottingham, Jubilee Campus, Nottingham, UK.|Advanced Data Analysis Centre, University of Nottingham, Nottingham, NG7 2RD, UK.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Garibaldi
mesh_terms: D018070:Biological Specimen Banks; D066264:Datasets as Topic; D006801:Humans
keywords: Big data; Biobanking; Biobanking strategy