title: A Quinoline Carboxamide Antimalarial Drug Candidate Uniquely Targets Plasmodia at Three Stages of the Parasite Life Cycle.
authors.affiliation: Department of Chemistry, University of Liverpool, Liverpool, L69 7ZD (UK). pmoneill@liverpool.ac.uk.
authors.forename: Paul M
authors.initials: PM
authors.lastname: O'Neill
authors.affiliation: Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA (UK).
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Ward
mesh_terms: D000577:Amides / Q000737:chemistry / Q000494:pharmacology*; D000962:Antimalarials / Q000737:chemistry / Q000494:pharmacology*; D055808:Drug Discovery; D006801:Humans; D008018:Life Cycle Stages / Q000187:drug effects*; D015394:Molecular Structure; D021261:Parasitic Sensitivity Tests; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000254:growth & development*; D011804:Quinolines / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000577:Amides; D000962:Antimalarials; D011804:Quinolines
keywords: antimalarials; drug discovery; inhibitors; lead-optimization; medicinal chemistry