title: Spinal Metastases from a Primary Fallopian Tube Serous Adenocarcinoma: A Case Report.
abstract: Study Design Case report. Objective This case exemplifies the importance of a high index of suspicion when dealing with intractable pain and neurologic symptoms in patients with a history of cancer. Fallopian tube cancer is relatively uncommon, accounting for less than 0.2% of all female malignancies. Because of a low index of suspicion, it is often detected at an advanced stage. From an orthopedic perspective, osseous metastasis from primary fallopian tube malignancies is rare with only a few documented cases in the medical literature. Methods This case report documents a 68-year-old woman who developed back pain and leg weakness after undergoing surgical resection with adjuvant therapy of a primary fallopian tube adenocarcinoma. Her hospital course and follow-up are documented. Results Imaging revealed a compression fracture in the L1 vertebral body that when a biopsy confirmed a soft tissue diagnosis of a high-grade serous papillary adenocarcinoma of fallopian tube origin. The patient underwent a surgical decompression, posterior stabilization, and tumor debulking with postoperative resolution of her symptoms. Conclusions This is the first reported case of a spine metastasis from a fallopian tube serous carcinoma in a living patient. This case documents the diagnosis of a pathologic vertebral fracture due to metastasis of an atypical cancer.
authors.affiliation: Department of Anesthesiology, Tulane University Hospital, New Orleans, Louisiana, United States.
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Eskander
authors.affiliation: Department of Orthopedic Surgery, The University of Kansas School of Medicine-Wichita, Wichita, Kansas, United States.
authors.forename: Eren O
authors.initials: EO
authors.lastname: Kuris
authors.affiliation: Department of Orthopedics, Tulane University Hospital, New Orleans, Louisiana, United States.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Younghein
authors.affiliation: Department of Orthopedics, Tulane University Hospital, New Orleans, Louisiana, United States.
authors.forename: Samuel
authors.initials: S
authors.lastname: Landsman
authors.affiliation: Christiana Spine Center, Newark, Delaware, United States.
authors.forename: Leonard
authors.initials: L
authors.lastname: Japko
authors.affiliation: Christiana Spine Center, Newark, Delaware, United States.
authors.forename: Mark S
authors.initials: MS
authors.lastname: Eskander
keywords: FTC; L1; compression fracture; fallopian tube carcinoma; metastasis; serous adenocarcinoma; spine; vertebrae