title: A case of early extraneural medulloblastoma metastases in a young adult.
abstract: Extraneural metastases are a relatively rare manifestation of the primary brain tumors, and a major part of the cases has been associated with initial medulloblastoma. Herein, we present the case of a young female adult diagnosed and operated for medulloblastoma. The patient developed extraneural metastases in the first postoperative year. The condition exhibited an aggressive course of development, and the applied treatment approaches were unable to halt its progression. A short literature review identifies the predictive factors determining both prognosis and treatability of the condition; the current limitations and future perspectives of the treatment options are discussed.
authors.affiliation: Department of Neurosurgery, Tokuda Hospital, Sofia, Bulgaria.
authors.forename: Slavomir Iliev
authors.initials: SI
authors.lastname: Kondoff
authors.affiliation: Department of Neurosurgery, Tokuda Hospital, Sofia, Bulgaria.
authors.forename: Milko Dimitrov
authors.initials: MD
authors.lastname: Milev
authors.affiliation: Department of Neurosurgery, Tokuda Hospital, Sofia, Bulgaria.
authors.forename: Lili Naskova
authors.initials: LN
authors.lastname: Laleva
authors.affiliation: Department of Neurosurgery, Tokuda Hospital, Sofia, Bulgaria.
authors.forename: Christo Christov
authors.initials: CC
authors.lastname: Tzekov
authors.affiliation: Department of Anaesthesiology and Intensive Care, Tokuda Hospital, Sofia, Bulgaria.
authors.forename: Christina Petrova
authors.initials: CP
authors.lastname: Kostadinova
authors.affiliation: Department of Medical Imaging, Tokuda Hospital, Sofia, Bulgaria.
authors.forename: Galina Ivanova
authors.initials: GI
authors.lastname: Kirova-Nedyalkova
authors.affiliation: Department of Clinical Pathology, Tokuda Hospital, Sofia, Bulgaria.
authors.forename: Polina Danailova
authors.initials: PD
authors.lastname: Dakova
keywords: Extraneural metastasis; medulloblastoma; multimodal therapy of brain tumors; prognostic factors