title: Copper-Catalyzed Electrophilic Amination of Heteroarenes via C-H Alumination.
abstract: A highly efficient Cu-catalyzed electrophilic amination reaction of readily available heteroarenes with O-benzoyl hydroxylamines via a one-pot C-H alumination is reported. The reactions were catalyzed using 1 mol % of CuCl to afford various heteroaryl amines in good to excellent yields. The direct C-H lithiation/transalumination of heteroarenes and catalytic amination sequence can be performed in a single vessel on gram scales.
authors.affiliation: Department of Chemistry, Kwangwoon University , Seoul 01897, Republic of Korea.
authors.forename: Hongju
authors.initials: H
authors.lastname: Yoon
authors.affiliation: Department of Chemistry, Kwangwoon University , Seoul 01897, Republic of Korea.
authors.forename: Yunmi
authors.initials: Y
authors.lastname: Lee