title: Printable Bioelectronics To Investigate Functional Biological Interfaces.
abstract: Thin-film transistors can be used as high-performance bioelectronic devices to accomplish tasks such as sensing or controlling the release of biological species as well as transducing the electrical activity of cells or even organs, such as the brain. Organic, graphene, or zinc oxide are used as convenient printable semiconducting layers and can lead to high-performance low-cost bioelectronic sensing devices that are potentially very useful for point-of-care applications. Among others, electrolyte-gated transistors are of interest as they can be operated as capacitance-modulated devices, because of the high capacitance of their charge double layers. Specifically, it is the capacitance of the biolayer, being lowest in a series of capacitors, which controls the output current of the device. Such an occurrence allows for extremely high sensitivity towards very weak interactions. All the aspects governing these processes are reviewed here.
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona 4, 70126 Bari (Italy) http://www.luisatorsi.info.
authors.forename: Kyriaki
authors.initials: K
authors.lastname: Manoli
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona 4, 70126 Bari (Italy) http://www.luisatorsi.info.
authors.forename: Maria
authors.initials: M
authors.lastname: Magliulo
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona 4, 70126 Bari (Italy) http://www.luisatorsi.info.
authors.forename: Mohammad Yusuf
authors.initials: MY
authors.lastname: Mulla
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona 4, 70126 Bari (Italy) http://www.luisatorsi.info.
authors.forename: Mandeep
authors.initials: M
authors.lastname: Singh
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona 4, 70126 Bari (Italy) http://www.luisatorsi.info.
authors.forename: Luigia
authors.initials: L
authors.lastname: Sabbatini
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona 4, 70126 Bari (Italy) http://www.luisatorsi.info.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Palazzo
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Bari "Aldo Moro", Via Orabona 4, 70126 Bari (Italy) http://www.luisatorsi.info. luisa.torsi@uniba.it.
authors.forename: Luisa
authors.initials: L
authors.lastname: Torsi
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D025802:Electric Capacitance; D004573:Electrolytes / Q000737:chemistry; D004582:Electronics, Medical / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D006108:Graphite / Q000737:chemistry; D006801:Humans; D011327:Printing / Q000295:instrumentation / Q000379:methods*; D013816:Thermodynamics; D014173:Transistors, Electronic; D015034:Zinc Oxide / Q000737:chemistry
chemical_list: D004573:Electrolytes; D006108:Graphite; D015034:Zinc Oxide
keywords: capacitance; chiral resolution; organic transistors; sensors; thermodynamics