title: Transcatheter aortic valve replacement for native aortic valve regurgitation as a bridge to liver transplantation.
abstract: Coexistence of end-stage liver disease (ESLD) and severe valvular heart disease conveyed substantial risk for patients, oftentimes leading to exclusion from liver transplantation candidacy due to inability to safely offer cardiac surgery prior to transplantation. Several approaches have been described, including performing transplantation and valve surgery concurrently, or in sequence. Both options, however, have associated complications: catastrophic repercussion of peri-operative coagulopathy and organ dysfunction post-transplantation, respectively. The introduction of transcatheter procedures offered a safer alternative for high-risk patients; however, its recognized indications remained limited. A novel approach to this surgical dilemma by performing transcatheter aortic valve replacement (TAVR) for severe native aortic valve regurgitation in a patient on the liver transplant list has been presented. The procedure proved to be an effective management for the aortic valve insufficiency, improving our patient's hemodynamics in preparation for the subsequent orthotopic liver transplantation (OLT). © 2015 Wiley Periodicals, Inc.
authors.affiliation: Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Alduz S
authors.initials: AS
authors.lastname: Cabasa
authors.affiliation: Division of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota.
authors.forename: Mackram F
authors.initials: MF
authors.lastname: Eleid
authors.affiliation: Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota. SURIR@ccf.org.
authors.forename: Rakesh M
authors.initials: RM
authors.lastname: Suri
mesh_terms: D001022:Aortic Valve Insufficiency / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D001027:Aortography / Q000379:methods; D006328:Cardiac Catheterization / Q000295:instrumentation / Q000379:methods*; D000072226:Computed Tomography Angiography; D018618:Echocardiography, Doppler, Color; D017548:Echocardiography, Transesophageal; D058625:End Stage Liver Disease / Q000150:complications / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
keywords: aortic valve insufficiency; calcium score; off label indication