title: Anaesthetic Efficacy of Topical Benzocaine Gel Combined with Hyaluronidase for Supplemental Intrapulpal Injection in Teeth with Irreversible Pulpitis- A Double Blinded Clinical Trial.
abstract: OBJECTIVE
  Intrapulpal injection technique is one of the most commonly employed method to achieve profound pulpal anaesthesia during an endodontic procedure. To determine if the topical application of benzocaine gel along with hyaluronidase to the pulp chamber could reduce the pain felt with the intrapulpal injection technique.
  
  
  METHODS
  Two hundred patients with chronic irreversible pulpitis undergoing endodontic treatment for mandibular first molars in which the primary anaesthetic technique failed were selected and randomly divided into 2 groups. In the control group intrapulpal injection was administered with backpressure. In the experimental group topical application of 20% benzocaine gel mixed with hyaluronidase was done over the exposed pulp following which intrapulpal injection was administered with backpressure. Pain assessment was done on a visual analogue scale.
  
  
  RESULTS
  There was statistically significant difference (p<0.001) between the two groups. The mean value in the control group corresponded to the pain perception "strong", whereas that of the experimental group corresponded to the pain perception "weak".
  
  
  CONCLUSIONS
  Topical application of 20% benzocaine gel mixed with hyaluronidase to the exposed pulp reduces the pain encountered with the intrapulpal injection.
authors.affiliation: Professor & Head, Department of Conservative Dentistry and Endodontics, MNR Dental College , Telangana, India .
authors.forename: Sujatha Gopal
authors.initials: SG
authors.lastname: Sooraparaju
authors.affiliation: Director, Smile Bright Root Canal Academy , Madurai, India .
authors.forename: M
authors.initials: M
authors.lastname: Abarajithan
authors.affiliation: Professor & Head, Department of Conservative Dentistry and Endodontics, Ultra's Best Dental College , Madurai, Telangana, India .
authors.forename: Emmanuel Solomon
authors.initials: ES
authors.lastname: Sathish
authors.affiliation: Reader, Department of Conservative Dentistry And Endodontics, MNR Dental College , Telangana, India .
authors.forename: Nujella Bhaskara Padma
authors.initials: NB
authors.lastname: Suryakumari
authors.affiliation: Reader, Department of Oral And Maxillofacial Pathology, MNR Dental College , Telangana, India .
authors.forename: Kranti Kiran Reddy
authors.initials: KK
authors.lastname: Ealla
authors.affiliation: Post Graduate, Department of Conservative Dentistry and Endodontics, MNR Dental College , Telangana, India .
authors.forename: Winner
authors.initials: W
authors.lastname: Gade
keywords: Hot pulp; IAN block; Pulpal anaesthesia