title: Emerging treatments for recurrent prostate cancer.
abstract: Despite radical treatment, many men with prostate cancer will develop recurrence of their disease. In an exciting era of new therapies for prostate cancer in general, we focus on how these will specifically benefit those men with recurrent disease. We consider salvage treatments aimed at those with local recurrence confined to the prostate gland, therapies for those presenting with metastatic recurrence and the approach to men presenting with a rising prostate-specific antigen but no demonstrable disease (M0). In general, men with recurrent disease are often under-represented in randomized clinical trials. Consequently, evidence to guide treatment for these men is often lacking and this needs to be addressed in order to improve and better define our approach to this problem in the future.
authors.affiliation: Beatson West of Scotland Cancer Centre, 1053 Great Western Road, Glasgow, G12 0YN, UK.
authors.forename: Catherine
authors.initials: C
authors.lastname: Hanna
authors.affiliation: Institute of Cancer Sciences, University of Glasgow, Beatson West of Scotland Cancer Centre, 1053 Great Western Road, Glasgow, G12 0YN, UK.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Jones
mesh_terms: D017024:Chemotherapy, Adjuvant; D019468:Disease Management; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D008297:Male; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D064129:Prostatic Neoplasms, Castration-Resistant / Q000473:pathology / Q000628:therapy; D019233:Retreatment / Q000379:methods*; D016879:Salvage Therapy / Q000379:methods
keywords: cancer; cryotherapy; docetaxel; immunotherapy; prostate; prostatectomy; radiotherapy; recurrent; relapse; salvage