title: Duodenal involvement by seminomatous tumors.
abstract: Testicular germ cell tumors, though rare (1%), represent the most common neoplasm among young men. Gastrointestinal involvement from these malignancies usually presents as bowel obstruction and digestive bleeding, but their frequency is low (5%). The patterns of this involvement are: infiltration from affected retroperitoneal lymph nodes or, less frequently, by peritoneal seeding and direct hematogenous spread. Particularly, infiltration of duodenum is also rare, though its real frequency is not well defined. Moreover, the affinity for GI tract differs among the histological types of GCT, being seminomatous tumors an exceedingly unfrequent cause of duodenal infiltration. We herein present a recent case in our institution of severe anemia due to gastrointestinal bleeding in the context of giant retroperitoneal bulky metastatic mass infiltrating duodenum as first manifestation of a testicular pure seminoma.
authors.affiliation: Cirugía General y Digestiva, Hospital Universitario Río Hortega (Valladolid), España.
authors.forename: Mario
authors.initials: M
authors.lastname: Rodriguez-Lopez
authors.affiliation: Servicio de Cirugía General y del Aparato Digestiv, Hospital Universitario Río Hortega, España.
authors.forename: Rosalía
authors.initials: R
authors.lastname: Velasco-López
authors.affiliation: Servicio de Cirugía General y Digestiva, Hospital Universitario Rio Hortega, Valladolid, España.
authors.forename: Sara
authors.initials: S
authors.lastname: Mambrilla-Herrero
authors.affiliation: Cirugía General y Digestiva, Hospital Universitario Río Hortega Valladolid, España.
authors.forename: Martin
authors.initials: M
authors.lastname: Bailon-Cuadrado
authors.affiliation: Servicio de Cirugía General y Digestiva, Hospital Universitario Rio Hortega, Valladolid, España.
authors.forename: Katherine T
authors.initials: KT
authors.lastname: Plua
authors.affiliation: Servicio de Cirugía General y Digestiva, Hospital Universitario Rio Hortega, Valladolid, España.
authors.forename: Luis M
authors.initials: LM
authors.lastname: Diez-González
authors.affiliation: Servicio de Cirugía General y Digestiva, Hospital Universitario Rio Hortega, Valladolid, España.
authors.forename: Jose I
authors.initials: JI
authors.lastname: Blanco-Álvarez
authors.affiliation: Cirugía General y del Aparato Digestivo, Hospital Universitario Rio Hortega, Valladolid, España.
authors.forename: Enrique
authors.initials: E
authors.lastname: Asensio-Díaz
authors.affiliation: Servicio de Cirugía General y Digestiva, Hospital Universitario Rio Hortega, Valladolid, España.
authors.forename: Marta
authors.initials: M
authors.lastname: Gonzalo-Martín
authors.affiliation: Servicio de Cirugía General y Aparato Digestivo, Hospital Universitario Rio Hortega, España.
authors.forename: Baltasar
authors.initials: B
authors.lastname: Pérez-Saborido
authors.affiliation: Servicio de Cirugía General y Digestiva, Hospital Universitario Rio Hortega, Valladolid, España.
authors.forename: Jose L
authors.initials: JL
authors.lastname: Marcos-Rodríguez
mesh_terms: D000328:Adult; D004379:Duodenal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D005773:Gastroscopy; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D018239:Seminoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed