title: Transoral robotic surgery for carcinoma of unknown primary in the head and neck.
abstract: Multiple diagnostic and treatment paradigms exist for the management of carcinoma of unknown primary (CUP) metastatic to cervical lymph nodes. Transoral robotic surgery (TORS) has emerged as a modality for diagnosis and treatment of CUP, optimizing identification and resection of the primary tumor, although also preventing chemotherapy in a subset of patients. This article presents the authors' treatment paradigm and reviews the literature supporting the use of TORS in the management of CUP.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.|Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, Ohio.
authors.forename: Stephen Y
authors.initials: SY
authors.lastname: Kang
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Florida, Gainesville, Florida.
authors.forename: Peter T
authors.initials: PT
authors.lastname: Dziegielewski
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.|Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, Ohio.
authors.forename: Matthew O
authors.initials: MO
authors.lastname: Old
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.|Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, Ohio.
authors.forename: Enver
authors.initials: E
authors.lastname: Ozer
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery*; D008207:Lymphatic Metastasis; D009055:Mouth; D037981:Neck Dissection / Q000295:instrumentation / Q000379:methods*; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis*; D018714:Radiotherapy, Adjuvant; D020127:Recovery of Function; D065287:Robotic Surgical Procedures / Q000295:instrumentation / Q000379:methods*; D014068:Tonsillectomy / Q000295:instrumentation / Q000379:methods; D016896:Treatment Outcome
keywords: CUP; TORS; carcinoma unknown primary; head-neck squamous cell carcinoma; transoral robotic surgery