title: Comparison of the improvement in myocardial perfusion and function in cases of rapid and slow electrocardiographic stage dynamics between patients with TIMI-3 flow after primary angioplasty for acute myocardial infarction.
abstract: OBJECTIVE
  Post-PCI TIMI flow grade 3 in infarct-related artery not always is associated with follow-up improvement in myocardial perfusion and function. We compared the improvement in myocardial perfusion and function in cases of rapid and slow electrocardiographic (ECG) stage dynamics between patients with TIMI-3 flow after primary angioplasty for acute myocardial infarction (MI).
  
  
  METHODS
  Ten patients with post-PCI TIMI-3 flow were divided into group A (n=50, no rapid change of ECG stages) and group B (n=50, with a ≥2 ECG stages per 2 days change rate).
  
  
  RESULTS
  There were no significant changes after 3 months in scintigraphic (ejection fraction 44.6±9.3% vs. 42.0±3.4%, P=0.4; perfusion deficit severity 3.0±0.7 vs. 2.3±0.8, P=0.1) and echocardiographic (dysfunction score 1.9±0.2 vs. 1.6±0.5, P=0.2) data in group A. Scintigraphic data improved (ejection fraction 34.6±3.9% vs. 52.0±7.3, P=0.03; perfusion deficit severity 2.8±0.6 vs. 1.5±0.8, P=0.03) and changes in echocardiographic data were of borderline significance (dysfunction score 1.8±0.2 vs. 1.4±0.4, P=0.06) in group B.
  
  
  CONCLUSIONS
  There was not any change in myocardial perfusion and function in a case of slow change of ECG stages after reached post-PCI TIMI flow grade 3, while myocardial perfusion improved and function tended to improve in a case of the rate at least two ECG stages in 2 days after primary angioplasty for acute MI.
authors.affiliation: Department of Internal Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania. Electronic address: eglekalin@yahoo.com.
authors.forename: Eglė
authors.initials: E
authors.lastname: Kalinauskienė
authors.affiliation: Department of Internal Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: Albinas
authors.initials: A
authors.lastname: Naudžiūnas
mesh_terms: D000368:Aged; D017130:Angioplasty; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D055414:Myocardial Perfusion Imaging; D015425:Myocardial Reperfusion; D062645:Percutaneous Coronary Intervention; D011446:Prospective Studies; D013318:Stroke Volume; D017256:Technetium Tc 99m Sestamibi
chemical_list: D017256:Technetium Tc 99m Sestamibi
keywords: Echocardiography; Electrocardiogram; Myocardial infarction; Percutaneous coronary intervention; Tc-99m-sestamibi scintigraphy