title: Gastric cancer-can we rely only on endoscopic ultrasonography?
abstract: BACKGROUND
  Endoscopic ultrasonography (EUS) is considered to be the most precise method for locoregional staging, was commonly used for differentiating mucosal lesions from submucosal lesions. By contrast, computed tomography (CT) was used to detect the presence of distant metastasis. Both are valuable tools for the pre-operative evaluation of gastric cancer. With the introduction of new therapeutic options and the recent improvements in CT technology, further evaluation of the diagnostic accuracy of EUS and multidetector CT (MDCT) is needed.
  
  
  OBJECTIVE
  The present study was conducted to compare the staging accuracy of EUS with that of MDCT in series of patients and to evaluate their usefulness in association with the clinicopathological factors.
  
  
  METHODS
  In total, 277 patients with gastric lesions who underwent EUS and CT, hospitalized at Department of Gastroenterology and Hepatology, Clinical Center, University of Sarajevo. The results from the pre-operative EUS and MDCT were compared with the post-operative pathological findings.
  
  
  RESULTS
  Among the 277 patients, the overall accuracy of EUS and MDCT for T staging was 74.7% and 76.9%, respectively. Among the 141 patients with visualized primary lesions on MDCT, the overall accuracy of EUS and MDCT for T staging was 61.7% and 63.8%, respectively. The overall accuracy for N staging was 66% and 62.8%, respectively. The performance of EUS and MDCT for large lesions and lesions at the cardia and angle had significantly lower accuracy than that of other groups. For EUS, the early gastric cancer lesions with ulcerative changes had significantly lower accuracy than those without ulcerative changes.
  
  
  CONCLUSIONS
  For the pre-operative assessment of individual T and N staging in patients with gastric cancer, the accuracy of MDCT was close to that of EUS. Both EUS and MDCT are useful complementary modalities for the locoregional staging of gastric cancer.
authors.affiliation: Clinical Centre University of Sarajevo, Bosnia and Herzegovina.
authors.forename: A
authors.initials: A
authors.lastname: Mehmedovic
authors.affiliation: Clinical Centre University of Sarajevo, Bosnia and Herzegovina.
authors.forename: R
authors.initials: R
authors.lastname: Mesihovic
authors.affiliation: Clinical Centre University of Sarajevo, Bosnia and Herzegovina.
authors.forename: N
authors.initials: N
authors.lastname: Vanis