title: Is Photodynamic Therapy an Effective Treatment for Periodontal and Peri-Implant Infections?
abstract: Antimicrobial photodynamic therapy (PDT) has attracted much attention for the treatment of pathogenic biofilm associated with peridontitis and peri-implantitis. However, data from randomized controlled clinical studies (RCTs) are limited and, to some extent, controversial, making it difficult to provide appropriate recommendations. Therefore, the aims of the present study were (a) to provide an overview on the current evidence from RCTs evaluating the potential clinical benefit for the additional use of PDT to subgingival mechanical debridement (ie, scaling and root planing) alone in nonsurgical periodontal therapy; and (b) to provide clinical recommendations for the use of PDT in periodontal practice.
authors.affiliation: Department of Periodontology, School of Dental Medicine, University of Bern, Freiburgstr. 7, 3010 Bern, Switzerland. Electronic address: anton.sculean@zmk.unibe.ch.
authors.forename: Anton
authors.initials: A
authors.lastname: Sculean
authors.affiliation: Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Aoki
authors.affiliation: Department of Periodontology, School of Dental Medicine, Stony Brook University, Stony Brook, NY 11794, USA.
authors.forename: George
authors.initials: G
authors.lastname: Romanos
authors.affiliation: Department of Oral Surgery, Heinrich Heine University, Moorenstr. 5, 40225 Düsseldorf, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
authors.affiliation: Department of Periodontology, School of Dental Medicine, University of Bern, Freiburgstr. 7, 3010 Bern, Switzerland.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Miron
authors.affiliation: Department of Periodontology, Philipps University Marburg, Georg-Voigt-Str. 3, 35039 Marburg, Germany; Department of Prosthodontics, Iuliu Hatieganu University, Clinicilor str. 32, 400506 Cluj-Napoca, Romania.
authors.forename: Raluca
authors.initials: R
authors.lastname: Cosgarea
mesh_terms: D006801:Humans; D057873:Peri-Implantitis / Q000628:therapy; D010510:Periodontal Diseases / Q000628:therapy*; D010778:Photochemotherapy
keywords: Aggressive periodontitis; Bacterial biofilm; Chronic periodontitis; Peri-implantitis; Photodynamic therapy