title: Nanotechnology and regenerative therapeutics in plastic surgery: The next frontier.
abstract: The rapid ascent of nanotechnology and regenerative therapeutics as applied to medicine and surgery has seen an exponential rise in the scale of research generated in this field. This is evidenced not only by the sheer volume of papers dedicated to nanotechnology but also in a large number of new journals dedicated to nanotechnology and regenerative therapeutics specifically to medicine and surgery. Aspects of nanotechnology that have already brought benefits to these areas include advanced drug delivery platforms, molecular imaging and materials engineering for surgical implants. Particular areas of interest include nerve regeneration, burns and wound care, artificial skin with nanoelectronic sensors and head and neck surgery. This study presents a review of nanotechnology and regenerative therapeutics, with focus on its applications and implications in plastic surgery.
authors.affiliation: UCL Medical School, University College London (UCL), London, England, UK; Biomaterials & Advanced Drug Delivery Laboratory (BioADD), Stanford University School of Medicine, Stanford University, Stanford, CA, USA. Electronic address: aaron.tan@ucl.ac.uk.
authors.forename: Aaron
authors.initials: A
authors.lastname: Tan
authors.affiliation: Department of Plastic & Reconstructive Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, England, UK.
authors.forename: Reema
authors.initials: R
authors.lastname: Chawla
authors.affiliation: UCL Medical School, University College London (UCL), London, England, UK.
authors.forename: Natasha
authors.initials: N
authors.lastname: G
authors.affiliation: UCL Institute of Child Health, University College London (UCL), Great Ormond Street Hospital for Children NHS Foundation Trust, London, England, UK; School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland, UK.
authors.forename: Sara
authors.initials: S
authors.lastname: Mahdibeiraghdar
authors.affiliation: UCL Medical School, University College London (UCL), London, England, UK.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Jeyaraj
authors.affiliation: Biomaterials & Advanced Drug Delivery Laboratory (BioADD), Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
authors.forename: Jayakumar
authors.initials: J
authors.lastname: Rajadas
authors.affiliation: Wellman Centre for Photomedicine, Massachusetts General Hospital, Boston, MA, USA; Department of Dermatology, Harvard Medical School, Boston, MA, USA; Harvard-MIT Division of Health Sciences & Technology, Cambridge, MA, USA.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Hamblin
authors.affiliation: Centre for Nanotechnology & Regenerative Medicine, UCL Division of Surgery & Interventional Science, University College London (UCL), London, England, UK; NanoRegMed Ltd, London, England, UK.
authors.forename: Alexander M
authors.initials: AM
authors.lastname: Seifalian
mesh_terms: D002056:Burns / Q000628:therapy*; D006801:Humans; D019651:Plastic Surgery Procedures / Q000379:methods*; D013518:Surgery, Plastic / Q000379:methods*; D000068936:Theranostic Nanomedicine / Q000379:methods*; D023822:Tissue Engineering / Q000379:methods*
keywords: Cyborg tissue; Nanoelectronics; Nanoengineering; Nanotechnology; Plastic surgery; Theranostics