title: Statin reduces orbitopathy risk in patients with Graves' disease by modulating apoptosis and autophagy activities.
abstract: Statins use has been associated with reduced risk for developing orbitopathy among patients with Graves' disease. We hypothesize that statin reduces orbitopathy risk mainly by modulating both apoptosis and autophagy activities in patients with Graves' disease.
authors.affiliation: Department of Medicine and Surgery, University of Salerno, Via Salvatore Allende, 84081, Baronissi, Salerno, Italy. maubiful@unisa.it.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bifulco
authors.affiliation: Department of Medicine and Surgery, University of Salerno, Via Salvatore Allende, 84081, Baronissi, Salerno, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Ciaglia
mesh_terms: D017209:Apoptosis / Q000187:drug effects*; D001343:Autophagy / Q000187:drug effects*; D006111:Graves Disease / Q000150:complications*; D049970:Graves Ophthalmopathy / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D020011:Protective Agents / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D020011:Protective Agents
keywords: Autophagy; Graves’ orbitopathy; Statins