title: Performance of bioresorbable vascular scaffolds versus cobalt-chromium everolimus-eluting stent in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: a review of currently available clinical data.
abstract: Bioresorbable vascular scaffold (BVS) represents a breakthrough in interventional cardiology. Despite BVS is used in various settings, nowadays only few studies compared BVS outcome with everolimus-eluting stent (EES) in ST-elevation myocardial infarction. We analyzed the currently available scientific data of direct and indirect comparison between BVS and EES in primary percutaneous coronary intervention (PPCI). Our paper highlights consistently different procedural techniques between BVS and EES. Across the wide spectrum of the studies analyzed, the clinical outcomes was similar between the two treatments. Some studies show an increased rate of device thrombosis although never significant and probably related to the technique of implantation. According to our analysis, from several points of view the BVS technology appears not inferior to EES in PPCI. Moreover, in this setting BVS seems an intriguing option for young patients, due to frequent incidence of single vessel disease in these patients, restore of vascular motility after reabsorption and no presence of ethernal prosthesis. However, we deem necessary a direct comparison between the two technologies, assessing hard clinical endpoints.
authors.affiliation: Azienda Ospedaliera Fatebenefratelli, Milan, Italy - bcortese@gmail.com.
authors.forename: Dario
authors.initials: D
authors.lastname: Buccheri
authors.forename: Davide
authors.initials: D
authors.lastname: Piraino
authors.forename: Paola R
authors.initials: PR
authors.lastname: Chirco
authors.forename: Bernardo
authors.initials: B
authors.lastname: Cortese
mesh_terms: D020341:Absorbable Implants; D002858:Chromium Alloys / Q000737:chemistry; D054855:Drug-Eluting Stents; D000068338:Everolimus / Q000008:administration & dosage; D006801:Humans; D062645:Percutaneous Coronary Intervention / Q000379:methods; D011474:Prosthesis Design; D000072657:ST Elevation Myocardial Infarction / Q000628:therapy*; D013927:Thrombosis / Q000453:epidemiology
chemical_list: D002858:Chromium Alloys; D000068338:Everolimus