title: Influence of multi-step etch-and-rinse versus self-etch adhesive systems on the post-operative sensitivity in medium-depth carious lesions: An in vivo study.
abstract: OBJECTIVE
  To evaluate the influence of a three-step etch-and-rinse versus a two-step self-etch adhesive system on immediate post-operative sensitivity.
  
  
  METHODS
  In total, 204 subjects with one posterior tooth affected by a primary carious lesion were recruited. The subjects were randomly divided into two groups, based on the two multi-step adhesive systems used: Group A (All Bond 3) and Group B (Clearfil Protect Bond). The same skilled operator carried out the restorations using a nano-hybrid composite (Venus Diamond) in oblique stratification. Each increment was light-cured for 20 seconds with a LED lamp (Translux Power Blue). Subjects received a three-level thermal sensitivity questionnaire for post-operative sensitivity ratings. The evaluations were recorded daily for 7 days. Scores were analyzed using the McNemar test and postoperative trends were analyzed with the Friedman test (P < 0.05). All (100%) enrolled subjects completed the follow-up visits. There was no statistically significant difference between the two groups in post-operative sensitivity trends. In both groups, increased post-operative sensitivity was found at D1, which then decreased significantly during the observation period.
  
  
  RESULTS
  The results of this in vivo study showed that both of the tested adhesives, etch-and-rinse or self-etch, provided effective dentin sealing, preventing subjects from experiencing post-operative sensitivity in the treatment of medium-depth cavities.
authors.forename: Nicola
authors.initials: N
authors.lastname: Scotti
authors.forename: Emanuele
authors.initials: E
authors.lastname: Bergantin
authors.forename: Roberta
authors.initials: R
authors.lastname: Giovannini
authors.forename: Laura
authors.initials: L
authors.lastname: Delbosco
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Breschi
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Migliaretti
authors.forename: Damiano
authors.initials: D
authors.lastname: Pasqualini
authors.forename: Elio
authors.initials: E
authors.lastname: Berutti
mesh_terms: D000134:Acid Etching, Dental; D003731:Dental Caries / Q000503:physiopathology* / Q000628:therapy; D003738:Dental Cements; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D003738:Dental Cements