title: Lymph nodes can accurately be measured on PET-CT for lymphoma staging/restaging without a concomitant contrast enhanced CT scan.
abstract: Dual imaging with both contrast enhanced CT scan and PET-CT is recommended for evaluation of lymphoma. We compared the performance in identification and size measurements of involved lymph nodes in FDG-avid lymphomas on the low dose non-contrast enhanced CT of a PET-CT scan with those on a diagnostic contrast enhanced CT scan. The size of FDG-avid lymph nodes was measured in both the short and long axis on both the low dose non-contrast CT of the PET-CT and the contrast enhanced CT by two independent readers. A total of 307 FGD avid lymph nodes were identified in 52 patients. There was no statistically significant differences in the measured size of the nodes on the non-contrast and contrast enhanced scans (p=0.21). Baseline staging and restaging of FDG-avid lymphomas can be performed with one test, PET-CT, without an accompanying contrast enhanced CT scan, with no effect on the measured nodal size.
authors.affiliation: a Department of Radiology , Body Imaging Section, Icahn School of Medicine at Mount Sinai , New York , NY , USA ;
authors.forename: William L
authors.initials: WL
authors.lastname: Simpson
authors.affiliation: a Department of Radiology , Body Imaging Section, Icahn School of Medicine at Mount Sinai , New York , NY , USA ;
authors.forename: Karen M
authors.initials: KM
authors.lastname: Lee
authors.affiliation: b Department of Radiology, Division of Nuclear Medicine , Icahn School of Medicine at Mount Sinai , New York , NY , USA ;|c Department of Radiology , Hospital General Plaza de la Salud , Santo Domingo , Dominican Republic ;
authors.forename: Ninoska
authors.initials: N
authors.lastname: Sosa
authors.affiliation: a Department of Radiology , Body Imaging Section, Icahn School of Medicine at Mount Sinai , New York , NY , USA ;
authors.forename: Nancy
authors.initials: N
authors.lastname: Cooper
authors.affiliation: d Department of Medicine, Division of Hematology and Medical Oncology , Icahn School of Medicine at Mount Sinai , New York , NY , USA ;
authors.forename: Eileen
authors.initials: E
authors.lastname: Scigliano
authors.affiliation: d Department of Medicine, Division of Hematology and Medical Oncology , Icahn School of Medicine at Mount Sinai , New York , NY , USA ;
authors.forename: Joshua D
authors.initials: JD
authors.lastname: Brody
authors.affiliation: e Department of Preventative Medicine , Icahn School of Medicine at Mount Sinai , New York , NY , USA.
authors.forename: John T
authors.initials: JT
authors.lastname: Doucette
authors.affiliation: b Department of Radiology, Division of Nuclear Medicine , Icahn School of Medicine at Mount Sinai , New York , NY , USA ;
authors.forename: Lale
authors.initials: L
authors.lastname: Kostakoglu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008198:Lymph Nodes / Q000473:pathology*; D008223:Lymphoma / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D015588:Observer Variation; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D003287:Contrast Media; D019275:Radiopharmaceuticals
keywords: Computed tomography; FDG-avid; lymph node; lymphoma; positron emission tomography