title: Association between atypical parathyroid adenoma and neurofibromatosis.
abstract: Primary hyperparathyroidism is a disease characterized by excessive production of parathyroid hormone (PTH), which is due to a parathyroid adenoma in 85% of cases. An atypical parathyroid adenoma, with some histopathological features of parathyroid carcinoma, may be found in some of the cases, although it may not fulfill all the criteria for this diagnosis. Neurofibromatosis type 1 (NF1) is an autosomal dominant systemic disease that may be associated with hyperparathyroidism. We report here the rare combination of a patient with NF1 and clinical manifestations of hyperparathyroidism due to an atypical parathyroid adenoma.
authors.affiliation: Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
authors.forename: Aline Mesquita Ferreira de
authors.initials: AM
authors.lastname: Favere
authors.affiliation: Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
authors.forename: Daniela Miti
authors.initials: DM
authors.lastname: Tsukumo
authors.affiliation: Departamento de Anatomia Patológica, FCM, Unicamp, Campinas, SP, Brasil.
authors.forename: Patrícia Sabino de
authors.initials: PS
authors.lastname: Matos
authors.affiliation: Departamento de Radiologia, FCM, Unicamp, Campinas, SP, Brasil.
authors.forename: Sérgio Luiz Marques dos
authors.initials: SL
authors.lastname: Santos
authors.affiliation: Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
authors.forename: Cristina Alba
authors.initials: CA
authors.lastname: Lalli
mesh_terms: D000236:Adenoma / Q000150:complications / Q000473:pathology*; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000209:etiology; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications / Q000175:diagnosis*; D010281:Parathyroid Hormone / Q000032:analysis; D010282:Parathyroid Neoplasms / Q000150:complications / Q000473:pathology*; D011859:Radiography
chemical_list: D010281:Parathyroid Hormone