title: ST Segment Elevation ECG Changes During Pharmacologic Stress With Regadenoson.
abstract: Regadenoson is a pharmacologic stress agent that has been widely adopted as an alternative over other pharmacologic vasodilator agents due to its ease of use, patient tolerance, and safety profile. We report the case of dynamic ST-segment elevation electrocardiogram changes after regadenoson injection during an inpatient single-photon emission computed tomography myocardial perfusion stress test, with subsequent coronary angiography revealing the presence of hemodynamically significant coronary artery disease. Our findings confirm that transient regadenoson-induced ST-segment elevations are a marker for hemodynamically significant disease even in the setting of low-risk SPECT perfusion images.
authors.affiliation: From the *Division of Cardiology, Departments of Medicine and †Radiology, University of Southern California, Los Angeles, CA.
authors.forename: Salima
authors.initials: S
authors.lastname: Qamruddin
authors.forename: Henry W
authors.initials: HW
authors.lastname: Huang
authors.forename: Anil
authors.initials: A
authors.lastname: Mehra
authors.forename: Shahram
authors.initials: S
authors.lastname: Bonyadlou
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Yoon
mesh_terms: D058908:Adenosine A2 Receptor Agonists / Q000009:adverse effects*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D004562:Electrocardiography; D005080:Exercise Test; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging; D011687:Purines / Q000009:adverse effects*; D011720:Pyrazoles / Q000009:adverse effects*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D058908:Adenosine A2 Receptor Agonists; D011687:Purines; D011720:Pyrazoles; C430916:regadenoson