title: STIMATE reveals a STIM1 transitional state.
abstract: Decreases in endoplasmic reticulum calcium content are sensed by resident STIM proteins, which can activate plasma membrane Orai channels to facilitate Ca(2+) entry. The role of STIMATE, a previously unknown component of the store-operated calcium entry complex, has now been identified and defined.
authors.affiliation: Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Hooper
authors.affiliation: Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.|Department of Medical Genetics &Molecular Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Soboloff
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D020543:Proteome / Q000378:metabolism*
chemical_list: D008565:Membrane Proteins; D020543:Proteome; D002118:Calcium