title: Oncogenic activation of MPL/thrombopoietin receptor by 17 mutations at W515: implications for myeloproliferative neoplasms.
authors.affiliation: Cell Signaling Pole, Signal Transduction and Molecular Hematology, Ludwig Institute for Cancer Research and de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: J-P
authors.initials: JP
authors.lastname: Defour
authors.affiliation: Cell Signaling Pole, Signal Transduction and Molecular Hematology, Ludwig Institute for Cancer Research and de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Chachoua
authors.affiliation: Cell Signaling Pole, Signal Transduction and Molecular Hematology, Ludwig Institute for Cancer Research and de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Pecquet
authors.affiliation: Cell Signaling Pole, Signal Transduction and Molecular Hematology, Ludwig Institute for Cancer Research and de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: S N
authors.initials: SN
authors.lastname: Constantinescu
mesh_terms: D000818:Animals; D002460:Cell Line; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D009154:Mutation; D009196:Myeloproliferative Disorders / Q000235:genetics*; D009857:Oncogenes; D053628:Receptors, Thrombopoietin / Q000235:genetics*
chemical_list: D053628:Receptors, Thrombopoietin; C082218:MPL protein, human