title: Results of a Multimodal Program During Hospitalization in Obese COPD Exacerbated Patients.
abstract: The objective of this study was to analyze the results of a multimodal therapeutic program during hospitalization in obese AECOPD patients. This was a randomized, single-blind clinical trial conducted at two university hospitals in Granada, Spain. Forty-nine patients hospitalized due to AECOPD were randomly allocated to a control group (CG), in which patients received standard care, or to an intervention group (IG), in which patients were included in a multimodal therapeutic program, added to the standard care. The main outcome measures were pulmonary, physical (strength and exercise capacity) and perceived (dyspnea, quality of life and psychological distress) variables. Within-group significant improvements (p < 0.05) were found in physical and perceived variables in the IG after the treatment. In the CG, a significant decrease was found in lower limb strength and a significant improvement in dyspnea and in three subscales of the EuroQol-5D questionnaire. The between-groups analysis showed significant differences after the treatment on lower limb strength and exercise capacity values (p < 0.05), in three of the EuroQol-5D subscales, and in the total score and the depression subscale of the Hospital Anxiety and Depression Scale. A multimodal therapeutic program has a beneficial effect on physical functioning and perceived variables in hospitalized obese patients with AECOPD.
authors.affiliation: a Department of Physical Therapy, School of Health Sciences . University of Granada , Spain.
authors.forename: Irene
authors.initials: I
authors.lastname: Torres-Sánchez
authors.affiliation: a Department of Physical Therapy, School of Health Sciences . University of Granada , Spain.
authors.forename: Marie Carmen
authors.initials: MC
authors.lastname: Valenza
authors.affiliation: b Pulmonary Medicine Service , Virgen de las Nieves University Hospital, Granada, Andalusian Health Service , Spain.
authors.forename: Germán
authors.initials: G
authors.lastname: Sáez-Roca
authors.affiliation: a Department of Physical Therapy, School of Health Sciences . University of Granada , Spain.
authors.forename: Irene
authors.initials: I
authors.lastname: Cabrera-Martos
authors.affiliation: a Department of Physical Therapy, School of Health Sciences . University of Granada , Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: López-Torres
authors.affiliation: a Department of Physical Therapy, School of Health Sciences . University of Granada , Spain.
authors.forename: Jeanette
authors.initials: J
authors.lastname: Rodríguez-Torres
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000523:psychology; D001945:Breathing Exercises / Q000379:methods*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003863:Depression / Q000523:psychology; D018450:Disease Progression; D004417:Dyspnea / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D005081:Exercise Therapy / Q000379:methods*; D017079:Exercise Tolerance; D005260:Female; D005541:Forced Expiratory Volume; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D009765:Obesity / Q000150:complications / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D010092:Oximetry; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D016037:Single-Blind Method; D013315:Stress, Psychological / Q000523:psychology; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D001993:Bronchodilator Agents
keywords: exacerbation; exercise; hospital stay; pulmonary rehabilitation