title: Outer Retinal Changes Preceding Secondary Macular Hole Formation Years After Vitreomacular Traction Release Demonstrated on Spectral-Domain OCT.
abstract: This report describes changes documented on spectral-domain optical coherence tomography (SD-OCT) in the right eye of a 58-year-old woman who eventually developed a secondary full-thickness macular hole (FTMH). She had a history of vitreomacular traction (VMT) that had resolved spontaneously with a complete posterior vitreous detachment. Despite VMT resolution, a hyperreflective band from the internal to the external limiting membrane and evidence of photoreceptor disruption persisted on SD-OCT for 2 years, at which point an FTMH developed. Despite VMT release, the unexpected FTMH coupled with the preceding outer retinal changes suggest persistent secondary damage to Müller cells as a potential factor.
authors.forename: Adam T
authors.initials: AT
authors.lastname: Chin
authors.forename: Marco A
authors.initials: MA
authors.lastname: Bonini Filho
authors.forename: Talisa E
authors.initials: TE
authors.lastname: de Carlo
authors.forename: Mehreen
authors.initials: M
authors.lastname: Adhi
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D012075:Remission, Spontaneous; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000503:physiopathology*; D012167:Retinal Perforations / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D000267:Tissue Adhesions / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014822:Vitreous Body / Q000503:physiopathology; D020255:Vitreous Detachment / Q000503:physiopathology*