title: Nasal Skin Necrosis: An Unexpected New Finding in Severe Chikungunya Fever.
abstract: Three adult Venezuelan patients with virologically confirmed Chikungunya fever, who developed extensive acute nasal skin necrosis early in the course of a life-threatening illness characterized by shock and multiple organ dysfunction syndrome, are discussed. One patient survived and fully recovered. Nasal necrosis has not previously been associated with the disease.
authors.affiliation: InfectologySection, Tropical Medicine Institute, Universidad Central de Venezuela.
authors.forename: Jaime R
authors.initials: JR
authors.lastname: Torres
authors.affiliation: InfectologySection, Tropical Medicine Institute, Universidad Central de Venezuela.
authors.forename: Leopoldo G
authors.initials: LG
authors.lastname: Córdova
authors.affiliation: InfectologySection, Tropical Medicine Institute, Universidad Central de Venezuela.
authors.forename: Víctor
authors.initials: V
authors.lastname: Saravia
authors.affiliation: Clínica RESCARVEN de Chuao, Caracas, Venezuela.
authors.forename: Joanne
authors.initials: J
authors.lastname: Arvelaez
authors.affiliation: InfectologySection, Tropical Medicine Institute, Universidad Central de Venezuela.
authors.forename: Julio S
authors.initials: JS
authors.lastname: Castro
mesh_terms: D000328:Adult; D000368:Aged; D065632:Chikungunya Fever / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D008875:Middle Aged; D009336:Necrosis / Q000209:etiology / Q000473:pathology; D009666:Nose / Q000473:pathology; D009668:Nose Diseases / Q000209:etiology / Q000473:pathology; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology; D014687:Venezuela
keywords: Chikungunya fever; nasal skin necrosis; severe illness