title: A case report of primary cutaneous marginal zone lymphoma treated with intralesional steroids.
abstract: OBJECTIVE
  Primary cutaneous marginal zone lymphoma (PCMZL) is a low-grade malignant B-cell lymphoma that appears in the skin without any extracutaneous manifestations. Therapeutic mainstays for PCMZL have primarily included radiotherapy and surgery. Intralesional steroids have been found to resolve the lesions caused by PCMZL, but there is a dearth of literature regarding this therapy indicating that this is not a commonly favored treatment option.
  
  
  METHODS
  We present a case of 60-year-old woman who presented with PCMZL on her right eyebrow. Three years later, after two courses of radiation and one relapse, the patient presented with new lesions on both arms, consistent once again with PCMZL. At this time, therapy with nine rounds of intralesional triamcinolone was attempted. After each round of triamcinolone, gradual improvement of the lesions was noted until complete resolution occurred.
  
  
  CONCLUSIONS
  This case reminds practitioners that intralesional corticosteroids can be effectively and safely used to treat localized PCMZL. Intralesional steroids are less invasive, cheaper, and easier to administer than the majority of other recommended therapies for PCMZL. Thus, although they are often overlooked, intralesional corticosteroids should be more often considered when developing a treatment plan for localized PCMZL.
authors.affiliation: University of Missouri-Kansas City School of Medicine. ramyak48@gmail.com.
authors.forename: Ramya
authors.initials: R
authors.lastname: Kollipara
authors.forename: Amneet
authors.initials: A
authors.lastname: Hans
authors.forename: John
authors.initials: J
authors.lastname: Hall
authors.forename: Allison
authors.initials: A
authors.lastname: Lisle
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001132:Arm / Q000473:pathology*; D001706:Biopsy; D005138:Eyebrows / Q000473:pathology*; D005153:Facial Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D018442:Lymphoma, B-Cell, Marginal Zone / Q000188:drug therapy* / Q000532:radiotherapy; D008875:Middle Aged; D012008:Recurrence; D012074:Remission Induction; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D014221:Triamcinolone / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; D014221:Triamcinolone