title: Optimal blood pressure in patients with peripheral artery disease following endovascular therapy.
abstract: This study examined the associations between blood pressure (BP) and event incidence to define optimal BP after endovascular therapy (EVT) in patients who underwent EVT. BP was monitored every 6 months for 5 years, and the patients were divided into two groups by average BP: ≥ 140/90 mmHg and < 140/90 mmHg. The association of BP with several events was examined. Although no significant differences in total mortality were observed between the groups, restenosis rates were significantly higher among patients who did not achieve target BP (36.2%) than among those who did (18.2%) (p < 0.01). The percentage of patients with glycosylated haemoglobin > 7.0% was significantly higher among those who did not achieve target BP in the restenosis group (42.9%) than in the other group (10.8%) (p < 0.01). In the restenosis group, there was a significantly higher percentage of patients taking metformin (p < 0.01) than in the other group. Metformin seemed to be administered to patients with more severe diabetes mellitus. In conclusion, it is important to manage hypertension and diabetes to prevent restenosis after EVT.
authors.affiliation: a Division of Cardiology , Cardiovascular Center, Teine Keijinkai Hospital , Sapporo , Japan.
authors.forename: Haruki
authors.initials: H
authors.lastname: Sasaki
authors.affiliation: b Department of Cardiology , Sapporo Nishimaruyama Hospital , Sapporo , Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Ura
authors.affiliation: a Division of Cardiology , Cardiovascular Center, Teine Keijinkai Hospital , Sapporo , Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Hata
authors.affiliation: c Department of Nephrology , Teine Keijinkai Hospital , Sapporo , Japan.
authors.forename: Norihito
authors.initials: N
authors.lastname: Moniwa
authors.affiliation: c Department of Nephrology , Teine Keijinkai Hospital , Sapporo , Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Hasegawa
authors.affiliation: c Department of Nephrology , Teine Keijinkai Hospital , Sapporo , Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Takizawa
authors.affiliation: a Division of Cardiology , Cardiovascular Center, Teine Keijinkai Hospital , Sapporo , Japan.
authors.forename: Shigemichi
authors.initials: S
authors.lastname: Tanaka
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon; D055109:Ankle Brachial Index; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D003251:Constriction, Pathologic / Q000150:complications / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008297:Male; D008687:Metformin / Q000627:therapeutic use; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000150:complications / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D011446:Prospective Studies; D016019:Survival Analysis
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D008687:Metformin; C517652:hemoglobin A1c protein, human
keywords: Endovascular procedures; metformin; peripheral artery disease; restenosis