title: Predicting mortality in burn patients with bacteraemia.
abstract: OBJECTIVE
  To determine factors associated with mortality in burn patients with bacteraemia.
  
  
  BACKGROUND
  Previous studies have shown the negative impact of bacteraemia on the prognosis of burn patients, but only a few of these have analysed variables intervening in the clinical progress of these patients.
  
  
  METHODS
  A retrospective study of adult burn patients (n = 73) with bacteraemia (103 episodes) in a Burns Unit during the 2000-2013 period. The study collected demographic variables, and comorbidity, injury-related and clinical data related to bacteraemia. Variables related to hospital mortality were analysed using a multiple logistic regression model.
  
  
  RESULTS
  The cumulative incidence of bacteraemia was 4.4 episodes/100 patients. The mean age was 53.3 ± 19.2 years (65.8 % male). The median total body surface area (TBSA) was 35 %, while 50.7 % of the population had inhalation syndrome. The mean SOFA score at the onset of bacteraemia was 2.7 ± 3.8. The most common pathogen was Pseudomonas aeruginosa (17.5 %). The mortality rate was 24.7 %. The variables that were significantly associated with mortality were age (OR = 1.13), TBSA (OR = 1.05), SOFA score at the onset of bacteraemia (OR = 1.53) and recurrent bacteraemia (OR = 41.6).
  
  
  CONCLUSIONS
  In addition to conventional risk factors, recurrence and organ dysfunction at the onset of bacteraemia are also associated with mortality, while the pathogen involved is not a prognostic factor.
authors.affiliation: Burn Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Ceniceros
authors.affiliation: Clinical Epidemiology and Biostatistics Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.
authors.forename: Sonia
authors.initials: S
authors.lastname: Pértega
authors.affiliation: Burn Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain. ritagaleiras@hotmail.es.
authors.forename: Rita
authors.initials: R
authors.lastname: Galeiras
authors.affiliation: Burn Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.
authors.forename: Mónica
authors.initials: M
authors.lastname: Mourelo
authors.affiliation: Burn Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.
authors.forename: Eugenia
authors.initials: E
authors.lastname: López
authors.affiliation: Department of Health Information Technology, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Broullón
authors.affiliation: Internal Medicine, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.
authors.forename: Dolores
authors.initials: D
authors.lastname: Sousa
authors.affiliation: Burn Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Freire
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology / Q000401:mortality*; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification; D002056:Burns / Q000150:complications*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult
keywords: Bacteraemia; Burn patients; Mortality