title: Bioactive-glass in periodontal surgery and implant dentistry.
abstract: Bioactive-glass (B-G) is a material known for its favorable biological response when in contact with surrounding fibro-osseous tissues, due not only to an osteoconductive property, but also to an osteostimulatory capacity, and superior biocompatibility for use in human body. The objectives of this paper are to review recent studies on B-G in periodontal and implant therapy, describing its basic properties and mechanism of activity as well as discoursing about state of art and future perspective of utilization. From a demonstrated clinical benefit as bone graft for the elimination of osseous defects due to periodontal disease (intrabony/furcation defects) and surgeries (alveolar ridge preservation, maxillary sinus augmentation), to a potential use for manufacturing bioactive dental implants, possibly allowing wider case selection criteria together with improved integration rates even in the more challenging osteoporotic and medically compromised patients, this biomaterial represents an important field of study with high academic, clinical and industrial importance.
authors.affiliation: Department of Restorative Dentistry, Biomaterials Science, Biomimetics and Biophotonics (B3) Research Group, King's College London Dental Institute.
authors.forename: Andrea Corrado
authors.initials: AC
authors.lastname: Profeta
authors.forename: Gian Marco
authors.initials: GM
authors.lastname: Prucher
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry / Q000627:therapeutic use*; D018786:Bone Substitutes / Q000737:chemistry / Q000627:therapeutic use*; D015921:Dental Implants; D005898:Glass; D006801:Humans; D008443:Maxillary Sinus / Q000601:surgery; D010517:Periodontics / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D015921:Dental Implants