title: [BIOINFORMATICS COMPARISON OF HUMAN AND PLANT PHOSPHATOMES].
abstract: The study presents the results of bioinformatic comparison of protein phosphatases from higher plants and human phosphatom (150 sequences). Based on sequence and profile comparison with known catalytic domains, 204 plant homologues from Physcomitrella patens and Arabidopsis thaliana where selected. Clustering of joint group of plant and mammalian protein phosphatases revealed fundamental differences in plant and human phosphatomes. At the same time, it was shown significant differences in the set of protein phosphatases in P. patens, A. thaliana, and such monocots as Orysa saliva and Zea mays.
authors.forename: D A
authors.initials: DA
authors.lastname: Samofalova
authors.forename: P A
authors.initials: PA
authors.lastname: Karpov
authors.forename: Ya B
authors.initials: YB
authors.lastname: Blume
mesh_terms: D017360:Arabidopsis / Q000145:classification / Q000201:enzymology / Q000235:genetics*; D019068:Bryopsida / Q000145:classification / Q000201:enzymology / Q000235:genetics*; D020134:Catalytic Domain; D019295:Computational Biology; D006801:Humans; D005810:Multigene Family; D012275:Oryza / Q000145:classification / Q000201:enzymology / Q000235:genetics*; D010749:Phosphoprotein Phosphatases / Q000737:chemistry / Q000235:genetics*; D010802:Phylogeny; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D003313:Zea mays / Q000145:classification / Q000201:enzymology / Q000235:genetics*
chemical_list: D010940:Plant Proteins; D010749:Phosphoprotein Phosphatases