title: Management of oromandibular dystonia on a chorea acanthocytosis: a brief review of the literature and a clinical case.
abstract: BACKGROUND
  Chorea acanthocytosis is an extremely rare neurodegenerative condition characterized by neuropsychiatric disturbances, movement disorders, neuropathy, seizures, and acanthocytosis. In this case report, the authors will present the management of the oromandibular movement disorders associated with this disease.
  
  
  METHODS
  This case report describes the focal management of the severe orofacial manifestations associated with this condition. The therapeutic approach adopted to reduce the severe oromandibular movements, dysphagia, and the numerous oral ulcers was selective electromyography (EMG)-guided botulinum toxin application to the inferior head of the lateral pterygoid muscles and masseters. This would be applied to control severe and sudden oromandibular dystonia.
  
  
  RESULTS
  Through this procedure, the authors were able to reduce these severe oral manifestations, which had a major impact on the patient's quality of life, and temporarily improve vital functions, such as mastication, deglutition, and speech articulation.
  
  
  CONCLUSIONS
  Electromyography-guided botulinum toxin application may be a useful tool in the multimodal management of this condition.
authors.affiliation: a Faculty of Medicine Clínica Alemana Santiago Universidad Desarrollo , Santiago , Chile.|b Department of TMD and Orofacial Pain , Dental School of Medicine, Clínica Alemana Santiago - Universidad del Desarrollo , , Santiago , Chile.|d institution Director of Advance Occlusion Program , Universidad del Desarrollo .
authors.forename: Maria Cecilia Pesce
authors.initials: MC
authors.lastname: Ortega
authors.affiliation: a Faculty of Medicine Clínica Alemana Santiago Universidad Desarrollo , Santiago , Chile.|b Department of TMD and Orofacial Pain , Dental School of Medicine, Clínica Alemana Santiago - Universidad del Desarrollo , , Santiago , Chile.|e Clínical Coordinator of Advance Occlusion Program Universidad del Desarrollo .
authors.forename: Nicolás Patricio
authors.initials: NP
authors.lastname: Skármeta
authors.affiliation: c Universidad Autonoma , Santiago , Chile.
authors.forename: Yaglyn Jarpa
authors.initials: YJ
authors.lastname: Diaz
mesh_terms: D000328:Adult; D001905:Botulinum Toxins / Q000008:administration & dosage*; D004421:Dystonia / Q000175:diagnosis / Q000628:therapy*; D004576:Electromyography / Q000187:drug effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007273:Injections, Intramuscular; D008336:Mandibular Diseases / Q000175:diagnosis / Q000628:therapy*; D008406:Masseter Muscle / Q000187:drug effects; D054546:Neuroacanthocytosis / Q000175:diagnosis / Q000628:therapy*; D019226:Oral Ulcer / Q000175:diagnosis / Q000628:therapy; D011626:Pterygoid Muscles / Q000187:drug effects
chemical_list: D001905:Botulinum Toxins
keywords: Botulinum toxin; Chorea acanthocytosis; Electromyography; Movement disorders; Neurodegenerative diseases; Oromandibular dystonia