title: Modulation of host cell biology by plant pathogenic microbes.
abstract: Plant-pathogen interactions can result in dramatic visual changes in the host, such as galls, phyllody, pseudoflowers, and altered root-system architecture, indicating that the invading microbe has perturbed normal plant growth and development. These effects occur on a cellular level but range up to the organ scale, and they commonly involve attenuation of hormone homeostasis and deployment of effector proteins with varying activities to modify host cell processes. This review focuses on the cellular-reprogramming mechanisms of filamentous and bacterial plant pathogens that exhibit a biotrophic lifestyle for part, if not all, of their lifecycle in association with the host. We also highlight strategies for exploiting our growing knowledge of microbial host reprogramming to study plant processes other than immunity and to explore alternative strategies for durable plant resistance.
authors.affiliation: Sainsbury Laboratory (SLCU), University of Cambridge, Cambridge CB2 1LR, United Kingdom; email: ruth.le-fevre@slcu.cam.ac.uk , edouard.evangelisti@slcu.cam.ac.uk , thomas.rey@slcu.cam.ac.uk , sebastian.schornack@slcu.cam.ac.uk.
authors.forename: Ruth
authors.initials: R
authors.lastname: Le Fevre
authors.affiliation: Sainsbury Laboratory (SLCU), University of Cambridge, Cambridge CB2 1LR, United Kingdom; email: ruth.le-fevre@slcu.cam.ac.uk , edouard.evangelisti@slcu.cam.ac.uk , thomas.rey@slcu.cam.ac.uk , sebastian.schornack@slcu.cam.ac.uk.
authors.forename: Edouard
authors.initials: E
authors.lastname: Evangelisti
authors.affiliation: Sainsbury Laboratory (SLCU), University of Cambridge, Cambridge CB2 1LR, United Kingdom; email: ruth.le-fevre@slcu.cam.ac.uk , edouard.evangelisti@slcu.cam.ac.uk , thomas.rey@slcu.cam.ac.uk , sebastian.schornack@slcu.cam.ac.uk.
authors.forename: Thomas
authors.initials: T
authors.lastname: Rey
authors.affiliation: Sainsbury Laboratory (SLCU), University of Cambridge, Cambridge CB2 1LR, United Kingdom; email: ruth.le-fevre@slcu.cam.ac.uk , edouard.evangelisti@slcu.cam.ac.uk , thomas.rey@slcu.cam.ac.uk , sebastian.schornack@slcu.cam.ac.uk.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Schornack
mesh_terms: D001419:Bacteria / Q000276:immunology; D005658:Fungi / Q000276:immunology; D054884:Host-Pathogen Interactions / Q000276:immunology*; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology; D018517:Plant Roots / Q000276:immunology / Q000382:microbiology; D010944:Plants / Q000276:immunology* / Q000382:microbiology*
keywords: bacteria; cellular reprogramming; development; effectors; fungi; oomycetes