title: Fat Chance for Neural Stem Cells in Alzheimer's Disease.
abstract: Identifying factors driving neural stem cell dysfunction in age-related neurodegenerative diseases remains critical for the development of potential regenerative therapies. Now in Cell Stem Cell,Hamilton et al. (2015) find that lipid accumulation observed during early stages of Alzheimer's disease impairs neural stem cell activity in the adult brain.
authors.affiliation: Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA 94143, USA.
authors.forename: Geraldine
authors.initials: G
authors.lastname: Gontier
authors.affiliation: Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA 94143, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.
authors.forename: Karin
authors.initials: K
authors.lastname: Lin
authors.affiliation: Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA 94143, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: saul.villeda@ucsf.edu.
authors.forename: Saul A
authors.initials: SA
authors.lastname: Villeda
mesh_terms: D000818:Animals; D050356:Lipid Metabolism; D058953:Neural Stem Cells; D016548:Prosencephalon / Q000378:metabolism*