title: Bubbles with shock waves and ultrasound: a review.
abstract: The study of the interaction of bubbles with shock waves and ultrasound is sometimes termed 'acoustic cavitation'. It is of importance in many biomedical applications where sound waves are applied. The use of shock waves and ultrasound in medical treatments is appealing because of their non-invasiveness. In this review, we present a variety of acoustics-bubble interactions, with a focus on shock wave-bubble interaction and bubble cloud phenomena. The dynamics of a single spherically oscillating bubble is rather well understood. However, when there is a nearby surface, the bubble often collapses non-spherically with a high-speed jet. The direction of the jet depends on the 'resistance' of the boundary: the bubble jets towards a rigid boundary, splits up near an elastic boundary, and jets away from a free surface. The presence of a shock wave complicates the bubble dynamics further. We shall discuss both experimental studies using high-speed photography and numerical simulations involving shock wave-bubble interaction. In biomedical applications, instead of a single bubble, often clouds of bubbles appear (consisting of many individual bubbles). The dynamics of such a bubble cloud is even more complex. We shall show some of the phenomena observed in a high-intensity focused ultrasound (HIFU) field. The nonlinear nature of the sound field and the complex inter-bubble interaction in a cloud present challenges to a comprehensive understanding of the physics of the bubble cloud in HIFU. We conclude the article with some comments on the challenges ahead.
authors.affiliation: Institute of High Performance Computing , 1 Fusionopolis Way, 16-16 Connexis North, Singapore 138632 , Republic of Singapore.
authors.forename: Siew-Wan
authors.initials: SW
authors.lastname: Ohl
authors.affiliation: Institute of High Performance Computing , 1 Fusionopolis Way, 16-16 Connexis North, Singapore 138632 , Republic of Singapore.
authors.forename: Evert
authors.initials: E
authors.lastname: Klaseboer
authors.affiliation: Department of Mechanical Engineering , National University of Singapore , Block EA 07-08, 9 Engineering Drive 1, Singapore 117575 , Republic of Singapore.
authors.forename: Boo Cheong
authors.initials: BC
authors.lastname: Khoo
keywords: acoustic cavitation; biomaterials; bubble clouds; high-intensity focused ultrasound; sound waves