title: Urinary incontinence: Clinical observation on 30 patients undergoing treatment with F.R.E.M.S (Frequency Rhythmic Electrical Modulation System).
abstract: OBJECTIVE
  Urge incontinence is considered to be a dysfunctional pathology of social interest due to the psychological and relational implications of such disability, the elevated number of affected patients and the consequent treatment costs. We propose an innovative non-pharmacological and non-invasive care methodology: Frequency rhythmic electrical modulation system (F.R.E.M.S.) therapy (FT), based on the administration of electric fields of monophasic pulsed, negative, asymmetric current, generated by a neurostimulator with the characteristics of low variable frequency, high voltage and very low impulse duration.
  
  
  METHODS
  30 patients were studied with urodynamic evaluation and radiological diagnostic techniques, and underwent 2 cycles of 15 days therapy, with a 12 months follow-up.
  
  
  RESULTS
  In 93% of cases, we obtained a positive result, with either disappearance or improvement of symptoms.
  
  
  CONCLUSIONS
  Although the Authors believe that clinical results deserve further neurohistological and immunohistochemical studies, in order to define the anathomophysiological and biochemical changes induced by FT, they propose it as a possible alternative to traditional pharmacological therapy and electrical stimulation.
authors.affiliation: General Surgery Unit 1, Complesso Integrato Columbus, Catholic University of the Sacred Heart, Rome. massimo.massari@virgilio.it.
authors.forename: Massimo
authors.initials: M
authors.lastname: Massari
authors.forename: Patrizia
authors.initials: P
authors.lastname: Desideri
authors.forename: Paolo
authors.initials: P
authors.lastname: Menchinelli
authors.forename: Lucia
authors.initials: L
authors.lastname: Cerrito
authors.forename: Luciano
authors.initials: L
authors.lastname: De Giovanni
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D013997:Time Factors; D004561:Transcutaneous Electric Nerve Stimulation / Q000379:methods; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000503:physiopathology / Q000628:therapy*; D053202:Urinary Incontinence, Urge / Q000628:therapy