title: Unusual cause of lower extremity wounds: Cobb syndrome.
abstract: Cobb syndrome (Cutaneomeningospinal Angiomatosis) is a rare segmental neurocutaneous syndrome associated with metameric cutaneous and spinal cord arteriovenous malformations (AVMs). In this syndrome, capillary malformation or angiokeratoma-like lesions are formed in a dermatomal distribution, with an AVM in the corresponding segment of the spinal cord. The spinal cord lesions can cause neurological disorder and paraplegia, which typically develop during young adulthood. We report a 32-year-old male with the Cobb syndrome associated with lower extremity painful wounds and acute-onset paraplegia due to metameric vascular malformations.
authors.affiliation: Skin diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.|Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Bahareh
authors.initials: B
authors.lastname: Abtahi-Naeini
authors.affiliation: Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Saffaei
authors.affiliation: Cancer Research Center, Semnan University of Medical Sciences, Semnan, Iran. m.pourazizi@yahoo.com.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Pourazizi
mesh_terms: D000328:Adult; D000798:Angiomatosis / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007871:Leg Ulcer / Q000175:diagnosis* / Q000601:surgery*; D035002:Lower Extremity / Q000473:pathology*; D008297:Male; D017445:Skin Diseases, Vascular / Q000150:complications* / Q000601:surgery*; D012878:Skin Neoplasms / Q000473:pathology; D013577:Syndrome; D016896:Treatment Outcome
keywords: Angiokeratoma; Cobb syndrome; Leg ulcer; Wound