title: Radiation-associated sarcoma after recurrent colorectal primary tumor: A complex surgical case.
abstract: Radiation associated sarcoma is a significant consequence of cancer therapy. Incidence of radiation associated sarcoma correlates with overall radiotherapy exposure. Prognosis is generally poor with 5 year survival rates lower than that for spontaneously occurring sarcomas. Surgical management presents many challenges including having to work in irradiated tissue planes while trying to achieve negative margins. We present a patient with a rare radiation associated pelvic sarcoma whose course illustrates the complexity of this problem.
authors.affiliation: Department of Surgery, Alpert Medical School of Brown University, Providence, Rhode Island.
authors.forename: Andrew H
authors.initials: AH
authors.lastname: Stephen
authors.affiliation: Department of Surgery, Alpert Medical School of Brown University, Providence, Rhode Island.
authors.forename: Eleanor A
authors.initials: EA
authors.lastname: Fallon
authors.affiliation: Department of Pathology, Alpert Medical School of Brown University, Providence, Rhode Island.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Kalife
authors.affiliation: Department of Surgery, Miriam Hospital, Providence, Rhode Island.
authors.forename: Harold
authors.initials: H
authors.lastname: Wanebo
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000532:radiotherapy*; D009367:Neoplasm Staging; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D010386:Pelvic Neoplasms / Q000209:etiology* / Q000473:pathology; D011379:Prognosis; D011878:Radiotherapy / Q000009:adverse effects*; D012004:Rectal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D012509:Sarcoma / Q000209:etiology* / Q000473:pathology
keywords: pelvic sarcoma; radiation; radiation associated; sarcoma