title: Pulp tissue dissolution capacity of QMix 2in1 irrigation solution.
abstract: OBJECTIVE
  The aim of this study was to evaluate the tissue dissolution efficacy of four root canal irrigation solutions (sodium hypochlorite [NaOCl], chlorhexidine gluconate [CHX], Octenidine [OCT], and QMix 2in1) on bovine pulp tissue.
  
  
  METHODS
  Fifty bovine pulp tissue samples, each weighing 6.55 mg, were prepared and randomly divided into four experimental groups and one control group (n = 10) according to the dissolution irrigants used: (1) 5.25% NaOCl group; (2) 2% CHX group; (3) OCT group; (4) QMix 2in1 group; and (5) control group (saline solution). These samples were then placed into special bovine dentin reservoir models and immersed for 1 h with each test solution (0.1 mL of each) at room temperature. The pulp samples were then blotted dry and weighed again. The percentage of weight loss was calculated. Statistically analyzed with one-way analysis of variance and post-hoc Tukey tests (P = 0.05).
  
  
  RESULTS
  Saline solution did not dissolve the bovine pulp tissue. All groups, except OCT, dissolved pulp samples more effectively than the control group (P < 0.05). The highest tissue dissolution was observed in 5.25% NaOCl group (P < 0.05). No statistically significant difference was found between the tissue-dissolving effect between QMix 2in1 and those of 2% CHX.
  
  
  CONCLUSIONS
  Within the limitations of this in vitro study, NaOCl exhibited the best tissue-dissolving effect out of all solutions tested. CHX and QMix 2in1 were able to dissolve pulp tissue but less than NaOCl. OCT and saline solutions could not exhibit significantly tissue-dissolving effectiveness. This study shown that QMix 2in1 has little capacity to dissolve pulp tissue therefore used alone is not sufficient for this purpose.
authors.affiliation: Department of Endodontics, Bezmialem Vakif University, Istanbul, Turkiye.
authors.forename: Dilara
authors.initials: D
authors.lastname: Arslan
authors.affiliation: Department of Endodontics, Bezmialem Vakif University, Istanbul, Turkiye.
authors.forename: Mehmet Burak
authors.initials: MB
authors.lastname: Guneser
authors.affiliation: Department of Endodontics, Akdeniz University, Antalya, Turkiye.
authors.forename: Alper
authors.initials: A
authors.lastname: Kustarci
authors.affiliation: Department of Endodontics, Akdeniz University, Antalya, Turkiye.
authors.forename: Kursat
authors.initials: K
authors.lastname: Er
authors.affiliation: Depatment of Restorative Dentistry, Bezmialem Vakif University, Istanbul, Turkiye.
authors.forename: Seyda Herguner
authors.initials: SH
authors.lastname: Siso
keywords: Chlorhexidine; QMix 2in1; octenidine; pulp tissue; tissue-dissolving