title: Treatment and Follow-up of Human Papillomavirus Infected Women in a Municipality in Southern Brazil.
abstract: BACKGROUND
  This study aimed toanalyze the risk behavior for cervical cancer (CC) and the human papillomavirus (HPV) prevalence and resolution among women who received care through the private healthcare network of a municipality in southern Brazil.
  
  
  METHODS
  This descriptive and retrospective study was conducted with 25 women aged 20 to 59 years who received care through the private healthcare network and were treated at a specialty clinic in the period from January to December 2012 in a municipality in Northwest Parana, Southern Brazil. Data from medical records with cytological and HPV results were used. Following treatment, these women were followed-up and reassessed after 6 months. Data were statistically analyzed using the t-test and chi-squared test at a 5% significance level.
  
  
  RESULTS
  The mean age of the studied women was 27.8±7.75 years old, and the majority were married, with paid employment and were non-smokers. The mean age at menarche was 13.0±0.50 years old, and the mean age at first intercourse was 17.5±1.78 years, with only 8.0% (2) initiating sexual activity at an age ≤15 years old. The majority had 1 to 2 children (60.0%), while 88.0% reported having had one sexual partner in their lifetime, and all the women were sexually active. A total of 68.0% used a hormonal contraceptive method. All the women had leukorrhea and pain and were infected by a single HPV type. Regarding the lesion grade, 80.0% showed high risk and 20.0% low risk. The most prevalent high-risk HPV strain was 16.
  
  
  CONCLUSIONS
  These findings provide relevant information on HPV risk factors and infection, as well as the treatment and 6-month follow-up results, in economically and socially advantaged women with no traditional risk factors, corroborating previous reports that different risk factors may be described in different populations. Thus, this study reinforces the fact that even women without the traditional risk factors should undergo HPVmonitoring and assessment to determine the persistence of infection, promoting early diagnosis of the lesions presented and appropriate treatment to thus prevent the occurrence of CC.
authors.affiliation: Post-Graduate Program in Health Sciences, Maringa State University, Maringa, Parana, Programa de Pos Graduacao em Ciencias da Saude, Universidade Estadual de Maringa, Universidade Estadual de Maringa, Maringa, Brazil E-mail : catiaagnolo@gmail.com.
authors.forename: Joao Batista
authors.initials: JB
authors.lastname: Ruggeri
authors.forename: Catia Millene
authors.initials: CM
authors.lastname: Dell Agnolo
authors.forename: Angela Andreia Franca
authors.initials: AA
authors.lastname: Gravena
authors.forename: Marcela
authors.initials: M
authors.lastname: de Oliveira Demitto
authors.forename: Tiara Cristina Romeiro
authors.initials: TC
authors.lastname: Lopes
authors.forename: Silvana
authors.initials: S
authors.lastname: Delatorre
authors.forename: Maria Dalva
authors.initials: MD
authors.lastname: de Barros Carvalho
authors.forename: Marcia Edilaine Lopes
authors.initials: ME
authors.lastname: Consolaro
authors.forename: Sandra Marisa
authors.initials: SM
authors.lastname: Pelloso
mesh_terms: D000328:Adult; D000367:Age Factors; D001938:Brazil / Q000453:epidemiology; D003075:Coitus; D003278:Contraceptives, Oral, Hormonal; D005260:Female; D005500:Follow-Up Studies; D052162:Human papillomavirus 16; D006801:Humans; D007436:Intrauterine Devices, Medicated; D007973:Leukorrhea / Q000821:virology; D016912:Levonorgestrel / Q000627:therapeutic use; D008875:Middle Aged; D010146:Pain / Q000821:virology; D030361:Papillomavirus Infections / Q000150:complications / Q000453:epidemiology* / Q000821:virology; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012309:Risk-Taking; D012747:Sexual Partners; D000069339:Trachelectomy; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000821:virology; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000453:epidemiology* / Q000473:pathology / Q000821:virology
chemical_list: D003278:Contraceptives, Oral, Hormonal; D016912:Levonorgestrel