title: Mass-forming extramedullary hematopoiesis in multiple myeloma: 18F-FDG PET/CT is useful in excluding extramedullary myeloma involvement.
abstract: OBJECTIVE
  Extramedullary hematopoiesis (EMH), a benign condition, is usually observed in patients with hematologic disorders. We report the first case of mass-forming EMH detected on a 18F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan in a patient with multiple myeloma (MM).
  
  
  METHODS
  A 58-year-old woman underwent workup for bicytopenia, and was diagnosed with MM based on the results of bone marrow aspiration and serum protein electrophoresis. An 18F-FDG PET/CT scan revealed a paravertebral mass with mild FDG avidity, suggesting a tumorous condition.
  
  
  RESULTS
  Biopsy was performed to exclude malignancy and the mass was eventually confirmed as EMH.
  
  
  CONCLUSIONS
  Differential diagnosis of a mildly FDG-avid paravertebral mass in MM should include EMH.
authors.affiliation: Department of Nuclear Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
authors.forename: Minjung
authors.initials: M
authors.lastname: Seo
authors.affiliation: Department of Hematology and Cellular Therapy, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
authors.forename: Hawk
authors.initials: H
authors.lastname: Kim
authors.affiliation: Department of Hematology and Cellular Therapy, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
authors.forename: Jae-Cheol
authors.initials: JC
authors.lastname: Jo
authors.affiliation: Department of Hematology and Cellular Therapy, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
authors.forename: Yunsuk
authors.initials: Y
authors.lastname: Choi
authors.affiliation: Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
authors.forename: Hee Jeong
authors.initials: HJ
authors.lastname: Cha
authors.affiliation: Department of Laboratory Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
authors.forename: Ji-Hun
authors.initials: JH
authors.lastname: Lim
authors.affiliation: Department of Nuclear Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan - Korea.
authors.forename: Seol Hoon
authors.initials: SH
authors.lastname: Park
mesh_terms: D015415:Biomarkers; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology*; D000072078:Positron Emission Tomography Computed Tomography; D011856:Radiographic Image Enhancement; D013792:Thalidomide / Q000627:therapeutic use
chemical_list: D015415:Biomarkers; D019788:Fluorodeoxyglucose F18; D013792:Thalidomide