title: Autism Spectrum Disorder - A Complex Genetic Disorder.
abstract: Autism spectrum disorder is an entity that reflects a scientific consensus that several previously separated disorders are actually a single spectrum disorder with different levels of symptom severity in two core domains - deficits in social communication and interaction, and restricted repetitive behaviors. Autism spectrum disorder is diagnosed in all racial, ethnic and socioeconomic groups and because of its increased prevalence, reported worldwide through the last years, made it one of the most discussed child psychiatric disorders. In term of aetiology as several other complex diseases, Autism spectrum disorder is considered to have a strong genetic component.
authors.affiliation: Department of Pediatrics and Medical Genetics, Medical Faculty, Medical University, Plovdiv
authors.forename: Hristo Y
authors.initials: HY
authors.lastname: Ivanov
authors.affiliation: Department of Pediatrics and Medical Genetics, Medical Faculty, Medical University, Plovdiv|Department of Medical Genetics, St. George University Hospital, Plovdiv
authors.forename: Vili K
authors.initials: VK
authors.lastname: Stoyanova
authors.affiliation: Psychiatric Ward for Men, State Psychiatric Hospital, Pazardzhik
authors.forename: Nikolay T
authors.initials: NT
authors.lastname: Popov
authors.affiliation: Department of Pediatrics and Medical Genetics, Medical Faculty, Medical University, Plovdiv|Department of Plant Physiology and Molecular Biology, Paisii Hilendarski University, Plovdiv, Bulgaria
authors.forename: Tihomir I
authors.initials: TI
authors.lastname: Vachev
mesh_terms: D000067877:Autism Spectrum Disorder / Q000453:epidemiology / Q000209:etiology / Q000235:genetics*; D056915:DNA Copy Number Variations; D044127:Epigenesis, Genetic; D008040:Genetic Linkage; D055106:Genome-Wide Association Study; D006801:Humans; D015995:Prevalence