title: Phosphate Tether-Mediated Ring-Closing Metathesis for the Generation of Medium to Large,P-Stereogenic Bicyclo[n.3.1]phosphates.
abstract: A phosphate tether-mediated ring-closing metathesis study towards the synthesis ofP-stereogenic bicyclo[6.3.1]-, bicyclo[7.3.1]-, and bicyclo[8.3.1]phosphates is reported. This study demonstrates expanded utility of phosphate tether-mediated desymmetrization ofC2-symmetric, 1,3-anti-diol dienes in generating complex medium to large,P-stereogenic bicyclo[n.3.1]phosphates..
authors.affiliation: Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582.
authors.forename: Soma
authors.initials: S
authors.lastname: Maitra
authors.affiliation: Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582.
authors.forename: Jana L
authors.initials: JL
authors.lastname: Markley
authors.affiliation: Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582.
authors.forename: Rambabu
authors.initials: R
authors.lastname: Chegondi
authors.affiliation: Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582.
authors.forename: Paul R
authors.initials: PR
authors.lastname: Hanson
keywords: P-stereogenic phosphate; bicyclic phosphate triester; desymmetrization; phosphate tether; ring-closing metathesis; tripodal coupling