title: Mitotically active cellular fibroma of the ovary: a case report and literature review.
abstract: BACKGROUND
  The ovarian cellular fibrous tumor with mitotic figure >4 per 10 high power field without moderate to severe atypia is defined as mitotically active cellular fibroma according to the 2014 World Health Organization classification. As this category is new and rare now, we described here a case of MACF and reviewed the literature.
  
  
  METHODS
  We present a case of mitotically active cellular fibroma of the ovary with 10-year history that was treated with laparoscopic surgery.
  
  
  METHODS
  We reviewed the relevant literature using PubMed search system and analyzed the previous cases.
  
  
  RESULTS
  To date, only 5 cases of mitotically active cellular fibroma have been reported. Our patient is the first case of mitotically active cellular fibroma of the ovary treated with laparoscopic surgery.
  
  
  CONCLUSIONS
  MACF of the ovary is a newly defined category and few cases have been reported, while prognostic factors have also not yet been fully characterized. Long-term clinical follow-up is necessary.
authors.affiliation: Department of Pathology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. yamatakashi@mub.biglobe.ne.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamada
authors.affiliation: Department of Pathology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. kns099@poh.osaka-med.ac.jp.
authors.forename: Kimiaki
authors.initials: K
authors.lastname: Hattori
authors.affiliation: Department of Pathology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. pa1028@art.osaka-med.ac.jp.
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Satomi
authors.affiliation: Department of Pathology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. hirose@art.osaka-med.ac.jp.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Hirose
authors.affiliation: Department of Radiology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. rad091@poh.osaka-med.ac.jp.
authors.forename: Go
authors.initials: G
authors.lastname: Nakai
authors.affiliation: Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. gyn146@poh.osaka-med.ac.jp.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Daimon
authors.affiliation: Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. toukichirou220@msn.com.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hayashi
authors.affiliation: Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. y-terai@poh.osaka-med.ac.jp.
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Terai
authors.affiliation: Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan. m-ohmichi@poh.osaka-med.ac.jp.
authors.forename: Masahide
authors.initials: M
authors.lastname: Ohmichi
authors.affiliation: Department of Pathology, Jikei Daisan Hospital, 4-11-1, Izumihoncho, Komaeshi, Tokyo, 201-8601, Japan. maasafu@jikei.ac.jp.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Fukunaga
mesh_terms: D005260:Female; D005350:Fibroma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D010535:Laparoscopy; D008279:Magnetic Resonance Imaging; D008938:Mitosis / Q000502:physiology*; D064847:Multimodal Imaging; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D055815:Young Adult