title: Long Term and Intensive Use of Ophthalmic Topical Corticosteroids and the Risk of Positive Doping Test in Athletes: A Case Report.
abstract: BACKGROUND
  We express the detection of the prohibited substance prednisone, prednisolone in player's urine sample by long and intensive use eye steroid drops.
  
  
  METHODS
  In a rare case in Iranian football, a player's urine sample had corticosteroids. After all investigations, it was demonstrated that systemic effects can be induced by using long-term of ophthalmic prednisone.
  
  
  CONCLUSIONS
  It seems to be required to investigate the systemic effects on long term and excessive use of topical corticosteroid drops can have on the result of the sample analysis and showing positive results.
authors.affiliation: Sports Medicine Research Center, Tehran University of Medical Sciences, Tehran, IR Iran ; Medical Committee, Football Federation Islamic Republic of Iran (FFIRI), Tehran, IR Iran.
authors.forename: Tohid
authors.initials: T
authors.lastname: Seif Barghi
authors.affiliation: Department of Medicinal Chemistry, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
authors.forename: Farzad
authors.initials: F
authors.lastname: Kobarfard
authors.affiliation: Medical Committee, Football Federation Islamic Republic of Iran (FFIRI), Tehran, IR Iran.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Hashemian
authors.affiliation: Msn Student of Electronic Learning in Medical Education, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Jayran
authors.initials: J
authors.lastname: Zebardast
keywords: Doping in Sports; Glucocorticoids; Topical Administration