title: Repair of a traumatic subarachnoid-pleural fistula with the percutaneous injection of fibrin glue in a 2-year-old.
abstract: Subarachnoid-pleural fistulas (SPFs) are rare clinical entities that occur after severe thoracic trauma or iatrogenic injury during anterolateral approaches to the spine. Treatment of these fistulas often entails open repair of the dural defect. The authors present the case of an SPF in a 2-year-old female after a penetrating injury to the chest. The diagnosis of an SPF was suspected given the high chest tube output and was confirmed with a positive β2-transferrin test of the chest tube fluid, as well as visualization of dural defects on MRI. The dural defects were successfully repaired with CT-guided percutaneous epidural injection of fibrin glue alone. This case represents the youngest pediatric patient with a traumatic SPF to be treated percutaneously. This technique can be safely used in pediatric patients, offers several advantages over open surgical repair, and could be considered as an alternative first-line therapy for the obliteration of SPFs.
authors.affiliation: Departments of 1 Neurosurgery and.
authors.forename: Jason K
authors.initials: JK
authors.lastname: Chu
authors.affiliation: Departments of 1 Neurosurgery and.
authors.forename: Brandon A
authors.initials: BA
authors.lastname: Miller
authors.affiliation: Radiology, Emory University School of Medicine, Atlanta; and.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Bazylewicz
authors.affiliation: Radiology, Emory University School of Medicine, Atlanta; and.
authors.forename: John F
authors.initials: JF
authors.lastname: Holbrook
authors.affiliation: Pediatric Neurosurgery Associates, Children's Healthcare of Atlanta, Georgia.
authors.forename: Joshua J
authors.initials: JJ
authors.lastname: Chern
mesh_terms: D002675:Child, Preschool; D004388:Dura Mater / Q000473:pathology; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007268:Injections, Epidural; D010994:Pleura / Q000473:pathology; D010995:Pleural Diseases / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D016156:Respiratory Tract Fistula / Q000209:etiology / Q000628:therapy*; D013346:Subarachnoid Space / Q000473:pathology; D013898:Thoracic Injuries / Q000150:complications*; D013904:Thoracic Vertebrae / Q000473:pathology; D014168:Transferrin / Q000032:analysis; D014948:Wounds, Gunshot / Q000150:complications*
chemical_list: D015718:Fibrin Tissue Adhesive; D014168:Transferrin
keywords: ASIA = American Spinal Injury Association; CISS = constructive interference in steady state; EBP = epidural blood patch; NIPPV = noninvasive positive pressure ventilation; SPF = subarachnoid-pleural fistula; fibrin glue; gunshot wound; pediatrics; spinal penetrating injury; spine; subarachnoid-pleural fistula; technique; trauma