title: Novel Monoterpene Lactones from Cinnamomum inunctum.
abstract: Four new monoterpene lactones, 5-(2,3-dihydroxy-3-methylbutyl)-4-hydroxy-4-methyldihydrofuran-2(3H)-one (1), 5-(2,3-dihydroxy-3-methylbutyl)-4-methylfuran-2(5H)-one (2), 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (3) and 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (4), were isolated from the methanolic extract of the fruit of Cinnamomum inunctum, a folk medicine in Myanmar, together with a known compound, 3-hydroxy-4,4-dimethyl-4-butyrolactone (5). Their chemical structures were determined by spectral methods. Among these, 3 and 4 possessed unique spirolactone moieties.
authors.affiliation: Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation, Health and Nutrition.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fuchino
authors.forename: Aya
authors.initials: A
authors.lastname: Yazawa
authors.forename: Fumiyuki
authors.initials: F
authors.lastname: Kiuchi
authors.forename: Nobuo
authors.initials: N
authors.lastname: Kawahara
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Motoyoshi
authors.initials: M
authors.lastname: Satake
mesh_terms: D027424:Cinnamomum / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D007783:Lactones / Q000032:analysis* / Q000302:isolation & purification; D008958:Models, Molecular; D039821:Monoterpenes / Q000032:analysis* / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: D007783:Lactones; D039821:Monoterpenes; D010936:Plant Extracts