title: Miliary Tuberculosis Induced Acute Liver Failure.
abstract: Hepatobiliary tuberculosis is uncommon even in endemic countries. It is associated with a high mortality and is even diagnosed early in the disease course. Acute liver failure (ALF) caused by tuberculosis bacilli has been reported in only a few reports. All previous cases have been diagnosed by postmortem examination. Time to antituberculosis treatment is very critical. In case of suggestive findings on clinical and radiologic examination, antituberculosis treatment should be initiated immediately. Drug use can be a challenge in patients with ALF. However, as long as the other possible causes of ALF can be excluded and hepatotoxic drugs were avoided during the early course of treatment, such a highly fatal presentation of tuberculosis can be treated safely. Here, we report a case of acute liver failure as a presentation of miliary tuberculosis. He was treated successfully with antituberculosis treatment.
authors.affiliation: Department of Hematology, Van Training and Research Hospital, 65300 Van, Turkey.
authors.forename: Tayfur
authors.initials: T
authors.lastname: Toptas
authors.affiliation: Department of Internal Medicine, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Birkan
authors.initials: B
authors.lastname: Ilhan
authors.affiliation: Department of Infectious Diseases, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Bilgin
authors.affiliation: Department of Internal Medicine, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Elif
authors.initials: E
authors.lastname: Dincses
authors.affiliation: Department of Gastroenterology, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Ozdogan
authors.affiliation: Department of Hematology, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Isik
authors.initials: I
authors.lastname: Kaygusuz-Atagunduz
authors.affiliation: Department of Infectious Diseases, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Zekaver
authors.initials: Z
authors.lastname: Odabasi
authors.affiliation: Department of Infectious Diseases, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Volkan
authors.initials: V
authors.lastname: Korten
authors.affiliation: Department of Hematology, Marmara University Hospital, Istanbul, Turkey.
authors.forename: Tulin
authors.initials: T
authors.lastname: Firatli-Tuglular