title: PSEUDO UVEAL MELANOMA CAUSED BY OPTIC DISK DRUSEN WITH JUXTAPAPILLARY CHOROIDAL NEOVASCULAR MEMBRANE.
abstract: OBJECTIVE
  To describe two cases of choroidal hemorrhage caused by optic disk drusen-induced choroidal neovascularization simulating uveal melanoma.
  
  
  METHODS
  Observational case reports of two patients and brief review of the literature.
  
  
  RESULTS
  Two patients were referred with pigmented juxtapapillary lesions concerning for choroidal melanoma. Multimodal imaging revealed the presence of optic disk drusen with overlying choroidal neovascular membranes and peripapillary choroidal hemorrhage. Both patients were treated with antivascular endothelial growth factor and the lesions resolved.
  
  
  CONCLUSIONS
  In the setting of diagnostic uncertainty, careful multimodal imaging can assist in distinguishing between malignant choroidal melanoma and a benign simulating lesion. Optic disk drusen with associated neovascularization and hemorrhage should be included in the list of pseudomelanomas.
authors.affiliation: *Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, New York; †Department of Ophthalmology, St. John's Episcopal Hospital, Far Rockaway, New York; and ‡Department of Ophthalmology, Maimonides Medical Center, Brooklyn, New York.
authors.forename: Brian
authors.initials: B
authors.lastname: Marr
authors.forename: Benjamin
authors.initials: B
authors.lastname: Reinherz
authors.forename: Irina
authors.initials: I
authors.lastname: Belinsky
authors.forename: Norman A
authors.initials: NA
authors.lastname: Saffra
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000098:blood supply / Q000473:pathology*; D020256:Choroidal Neovascularization / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000209:etiology*; D009898:Optic Disk / Q000473:pathology*; D015594:Optic Disk Drusen / Q000150:complications* / Q000175:diagnosis; D041623:Tomography, Optical Coherence; D014604:Uveal Neoplasms / Q000175:diagnosis / Q000209:etiology*; D014792:Visual Acuity; D000098943:Uveal Melanoma