title: Gastroesophageal Reflux Disease and Sleeve Gastrectomy.
abstract: Gastroesophageal reflux disease (GERD) and/or hiatus hernia (HH) are one of the most common disorders of the upper gastrointestinal tract. Despite the positive effect of sleeve gastrectomy (SG) regarding weight loss and improvement in obesity co-morbidities, there are concerns about the development of de novo gastroesophageal reflux disease or worsening the existing GERD after this bariatric operation. Furthermore, controversy exists on the consequences of SG in lower esophageal sphincter function and about the ideal procedure when a hiatus hernia is preoperatively diagnosed or discovered during the laparoscopic SG. This review systematically investigates the incidence, the pathophysiology of GERD and/or HH in morbidly obese individuals before and after SG, and the treatment options for concomitant HH repair during laparoscopic sleeve gastrectomy.
authors.affiliation: Bariatric Unit, Heraklion University Hospital, University of Crete, 164 Erythreas Street, 714 09, Heraklion, Crete, Greece. melissas@med.uoc.gr.
authors.forename: John
authors.initials: J
authors.lastname: Melissas
authors.affiliation: Department of Surgery, Hospital Clínico "Dr Jose J. Aguirre", Faculty of Medicine, University of Chile, Santiago, Chile. ibraghet@hcuch.cl.
authors.forename: Italo
authors.initials: I
authors.lastname: Braghetto
authors.affiliation: Department of Surgery, Hospital Clínico "Dr Jose J. Aguirre", Faculty of Medicine, University of Chile, Santiago, Chile.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Molina
authors.affiliation: Division of General Surgery and Bariatric Centre of Excellence, Department of Medico-Surgical Sciences and Biotechnologies, "La Sapienza" University of Rome, Rome, Italy. gianfranco.silecchia@uniroma1.it.
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Silecchia
authors.affiliation: Division of General Surgery and Bariatric Centre of Excellence, Department of Medico-Surgical Sciences and Biotechnologies, "La Sapienza" University of Rome, Rome, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Iossa
authors.affiliation: Centre Hospitalier Universitaire de Nice, Hôpital de l'Archet, Pôle Digestif, Nice, F-06202, France. IANNELLI.A@chu-nice.fr.|Faculté de Médecine, Université de Nice-Sophia Antipolis, Nice, F-06107, France. IANNELLI.A@chu-nice.fr.
authors.forename: Antonio
authors.initials: A
authors.lastname: Iannelli
authors.affiliation: Week Surgery, Bariatric Unit, Padova University Hospital, Padova, Italy. mirto.foletto@unipd.it.
authors.forename: Mirto
authors.initials: M
authors.lastname: Foletto
mesh_terms: D005743:Gastrectomy / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000209:etiology / Q000517:prevention & control; D006551:Hernia, Hiatal / Q000150:complications* / Q000601:surgery; D006801:Humans; D010535:Laparoscopy; D009767:Obesity, Morbid / Q000150:complications* / Q000601:surgery*
keywords: Bariatric surgery; GERD; Gastroesophageal reflux disease; Hiatus hernia; Sleeve gastrectomy