title: Dependency of Phytoprostane Fingerprints of Must and Wine on Viticulture and Enological Processes.
abstract: Wine is one of the most consumed alcoholic beverages around the world. Red wine has demonstrated several benefits for health maintenance. One group of potential anti-inflammatory compounds is the phytoprostanes, oxidative degradation products of linolenic acid. The aim of the present study was to measure, for the first time, the phytoprostane content in wine and must by an UHPLC-QqQ-MS/MS method after solid-phase extraction. The data showed two predominant classes of phytoprostanes: F1- and D1-phytoprostane series. In wines, the total phytoprostane concentration ranged from 134.1 ± 2.3 to 216.2 ± 3.06 ng/mL. Musts showed concentrations between 21.4 ± 0.8 and 447.1 ± 15.8 ng/mL. The vinification and aging procedures for the production of wine seem to influence the final phytoprostane levels in red wine and to modify the phytoprostane profile. The high concentrations observed and previous reports on anti-inflammatory effects of phytoprostanes make further research on the benefits of phytoprostanes more important.
authors.affiliation: Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC , Campus de Espinardo 25, Murcia, Spain.|Food Science and Technology Department, Catholic University of Murcia (UCAM) , Murcia, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Marhuenda
authors.affiliation: Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC , Campus de Espinardo 25, Murcia, Spain.
authors.forename: Sonia
authors.initials: S
authors.lastname: Medina
authors.affiliation: Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC , Campus de Espinardo 25, Murcia, Spain.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Díaz-Castro
authors.affiliation: Clinical Analysis Service, University Hospital La Arrixaca , Murcia, Spain.
authors.forename: Pedro
authors.initials: P
authors.lastname: Martínez-Hernández
authors.affiliation: Bodegas Baigorri S.L., Samaniego, Paı́s Vasco, Spain.
authors.forename: Simón
authors.initials: S
authors.lastname: Arina
authors.affiliation: Food Science and Technology Department, Catholic University of Murcia (UCAM) , Murcia, Spain.
authors.forename: Pilar
authors.initials: P
authors.lastname: Zafrilla
authors.affiliation: Food Science and Technology Department, Catholic University of Murcia (UCAM) , Murcia, Spain.
authors.forename: Juana
authors.initials: J
authors.lastname: Mulero
authors.affiliation: Institut des Biomolécules Max Mousseron, UMR 5247 CNRS-Universités Montpellier 1 & Montpellier 2 - ENSCM , Montpellier, France.
authors.forename: Camille
authors.initials: C
authors.lastname: Oger
authors.affiliation: Institut des Biomolécules Max Mousseron, UMR 5247 CNRS-Universités Montpellier 1 & Montpellier 2 - ENSCM , Montpellier, France.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Galano
authors.affiliation: Institut des Biomolécules Max Mousseron, UMR 5247 CNRS-Universités Montpellier 1 & Montpellier 2 - ENSCM , Montpellier, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Durand
authors.affiliation: Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC , Campus de Espinardo 25, Murcia, Spain.
authors.forename: Federico
authors.initials: F
authors.lastname: Ferreres
authors.affiliation: Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS-CSIC , Campus de Espinardo 25, Murcia, Spain.
authors.forename: Angel
authors.initials: A
authors.lastname: Gil-Izquierdo
mesh_terms: D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D052616:Solid Phase Extraction; D027843:Vitis / Q000737:chemistry*; D014920:Wine / Q000032:analysis*
chemical_list: D010936:Plant Extracts; C424244:Prostane, herbal preparation
keywords: inflammation; lipid peroxidation; oxidative stress; phytoprostanes; red wine