title: [New findings about schizophrenia can provide new diagnostics and treatment].
abstract: Remarkable progress has been made in the understanding of schizophrenia in the past few years. A driving force has been genome wide association studies that have now led to the identification of over 100 vulnerability loci, implicating functions in the immune system, calcium signaling as well as dopamine and glutamate transmission. In coupling the genetic information to functional data sets from imaging and cognitive studies there is a promise of developing radically improved understanding of schizophrenia, and in some cases new therapies based on immune modulation. As we develop more knowledge and better therapies there will likely be a reduction in stigmatization that is a very real problem for those affected and their families.
authors.affiliation: Karolinska Institutet - MMK Stockholm, Sweden Karolinska Institutet - MMK Stockholm, Sweden.
authors.forename: Martin
authors.initials: M
authors.lastname: Schalling
authors.affiliation: Karolinska Institutet - Fysiologi och Farmakologi Stockholm, Sweden Karolinska Institutet - Fysiologi och Farmakologi Stockholm, Sweden.
authors.forename: Göran
authors.initials: G
authors.lastname: Engberg
authors.affiliation: Oslo Universitet - Klinisk medicin Oslo, Norway Oslo Universitet - Klinisk medicin Oslo, Norway.
authors.forename: Ole
authors.initials: O
authors.lastname: Andreassen
authors.affiliation: Karolinska Institutet - Fysiologi och Farmakologi Stockholm, Sweden Karolinska Institutet - Fysiologi och Farmakologi Stockholm, Sweden.
authors.forename: Sophie
authors.initials: S
authors.lastname: Erhardt
authors.affiliation: Uppsala Universitet - Neurovetenskap Uppsala, Sweden Uppsala Universitet - Neurovetenskap Uppsala, Sweden.
authors.forename: Janet
authors.initials: J
authors.lastname: Cunningham
authors.affiliation: Oslo Universitet - Klinisk medicin Oslo, Norway Oslo Universitet - Klinisk medicin Oslo, Norway.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Agartz
authors.affiliation: Karolinska Institutet - Institutionen för klinisk neurovetenskap Stockholm, Sweden Karolinska Institutet - Institutionen för klinisk neurovetenskap Stockholm, Sweden.
authors.forename: Predrag
authors.initials: P
authors.lastname: Petrovic
authors.affiliation: Karolinska Institutet - Institutionen för klinisk neurovetenskap Stockholm, Sweden Karolinska Institutet - Institutionen för klinisk neurovetenskap Stockholm, Sweden.
authors.forename: Simon
authors.initials: S
authors.lastname: Cervenka
authors.affiliation: Karolinska Institutet - Klinisk Neurovetenskap Stockholm, Sweden Karolinska Institutet - Klinisk Neurovetenskap Stockholm, Sweden.
authors.forename: Helena
authors.initials: H
authors.lastname: Fatouros-Bergman
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications; D003072:Cognition Disorders / Q000150:complications; D016207:Cytokines / Q000378:metabolism; D020022:Genetic Predisposition to Disease; D006801:Humans; D008279:Magnetic Resonance Imaging; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics / Q000276:immunology / Q000628:therapy; D057545:Social Stigma
chemical_list: D016207:Cytokines