title: Presentations and Outcome of Thyroiditis from a Tertiary Care Hospital of Karachi.
abstract: OBJECTIVE
  To assess the clinical presentations and short-term outcomes of patients with thyroiditis presenting to a tertiary care hospital in Karachi, Pakistan.
  
  
  METHODS
  Case series.
  
  
  METHODS
  Department of Endocrinology, Liaquat National Hospital, Karachi, from June 2014 to February 2015.
  
  
  METHODS
  Patients between 18 and 70 years of age with acute onset of thyroiditis confirmed on thyroid scan or clinical judgment presenting to the outpatient services were included in the study. Pregnant females, psychiatric patients and patients having other chronic illnesses were excluded from the study.
  
  
  RESULTS
  A total of 26 patients with thyroiditis attended the endocrine clinic. Mean age of patients was 41.2 ± 11.12 years. There were 18 (69.2%) females. Clinical presentations were fever (65.4%), tender neck (23.1%), goiter (19.2%), localized tenderness in neck and palpable lymph nodes (26.9%). Major symptoms reported were: sore throat (69.2%), weight loss (38.5%), upper respiratory tract infection, thyroid pain, tremor, sweating and fever of unknown origin in 26.9% cases. All the patients had raised Erythrocyte Sedimentation Rate (ESR). Low Thyroid Stimulating Hormone (TSH) < 0.4 mlU/L was seen in 88.5% and 57.7% had raised Free T4 > 1.8 ng/dL. Complete recovery was seen in 88.5% patients while 11.5% had early hypothyroidism.
  
  
  CONCLUSIONS
  Fever and sore throat were the main presenting features of thyroiditis patients. ESR was raised in all patients. A majority of patients had complete recovery with appropriate management; however, few cases developed hypothyroidism.
authors.affiliation: Department of Endocrinology, Liaquat National Hospital and Medical College, Karachi.
authors.forename: Saeed Ahmed
authors.initials: SA
authors.lastname: Mahar
authors.affiliation: Department of Endocrinology, Liaquat National Hospital and Medical College, Karachi.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Shahid
authors.affiliation: Department of Endocrinology, Liaquat National Hospital and Medical College, Karachi.
authors.forename: Aqiba
authors.initials: A
authors.lastname: Sarfaraz
authors.affiliation: Department of Medicine, Liaquat NationalHospital and Medical College, Karachi.
authors.forename: Zuhaib-u-Ddin
authors.initials: ZU
authors.lastname: Shaikh
authors.affiliation: Department of Community Medicine, APPNA Institute of Public Health, Jinnah Sindh Medical University, Karachi.
authors.forename: Shiraz
authors.initials: S
authors.lastname: Shaikh
authors.affiliation: Department of Medicine, Amjad Hospital, Karachi.
authors.forename: Nadia
authors.initials: N
authors.lastname: Shahid
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D005260:Female; D005335:Fever of Unknown Origin / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000453:epidemiology / Q000209:etiology; D010154:Pakistan / Q000453:epidemiology; D010612:Pharyngitis / Q000453:epidemiology / Q000209:etiology; D011446:Prospective Studies; D012424:Rural Population; D012959:Socioeconomic Factors; D062606:Tertiary Care Centers; D013966:Thyroiditis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D016896:Treatment Outcome; D014505:Urban Population; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones; D000894:Anti-Inflammatory Agents, Non-Steroidal