title: Bioactive C₁₇-Polyacetylenes in Carrots (Daucus carota L.): Current Knowledge and Future Perspectives.
abstract: C17-polyacetylenes (PAs) are a prominent group of oxylipins and are primarily produced by plants of the families Apiaceae, Araliaceae, and Asteraceae, respectively. Recent studies on the biological activity of polyacetylenes have indicated their potential to improve human health due to anticancer, antifungal, antibacterial, anti-inflammatory, and serotogenic effects. These findings suggest targeting vegetables with elevated levels of bisacetylenic oxylipins, such as falcarinol, by breeding studies. Due to the abundant availability, high diversity of cultivars, worldwide experience, and high agricultural yields, in particular, carrot (Daucus carota L.) genotypes are a very promising target vegetable. This paper provides a review on falcarinol-type C17-polyacetylenes in carrots and a perspective on their potential as a future contributor to improving human health and well-being.
authors.affiliation: Chair for Food Chemistry and Molecular Sensory Science, Technische Universität München , Lise-Meitner-Straße 34, D-85354 Freising, Germany.
authors.forename: Corinna
authors.initials: C
authors.lastname: Dawid
authors.affiliation: Julius Kühn-Institut (JKI), Federal Research Centre for Cultivated Plants, Institute for Breeding Research on Horticultural Crops , Erwin-Baur-Strasse 27, D-06484 Quedlinburg, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Dunemann
authors.affiliation: Biotechnology of Natural Products, Technische Universität München , Liesel-Beckmann-Strasse 1, D-85354 Freising, Germany.
authors.forename: Wilfried
authors.initials: W
authors.lastname: Schwab
authors.affiliation: Julius Kühn-Institut (JKI), Federal Research Centre for Cultivated Plants, Institute for Breeding Research on Horticultural Crops , Erwin-Baur-Strasse 27, D-06484 Quedlinburg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Nothnagel
authors.affiliation: Chair for Food Chemistry and Molecular Sensory Science, Technische Universität München , Lise-Meitner-Straße 34, D-85354 Freising, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Hofmann
mesh_terms: D000818:Animals; D018552:Daucus carota / Q000737:chemistry*; D006801:Humans; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D053279:Polyynes / Q000737:chemistry* / Q000494:pharmacology*; D014675:Vegetables / Q000737:chemistry
chemical_list: D010936:Plant Extracts; D053279:Polyynes
keywords: Daucus carota L.; bioactive polyacetylenes; bitterness; carrot; falcarindiol; falcarinol; human health