title: [Poly Implant Prothèse (PIP®) incidence of complications in breast reconstructive surgery: A retrospective comparative analysis].
abstract: BACKGROUND
  On 29 March 2010, the Poly Implant Prothèse (PIP(®)) breast prosthesis was withdrawn from the market by the ANSM. In this study we review our experience with PIP(®) implants in breast reconstruction. We compare our complications with other types of breast implants used during the same period at our institution.
  
  
  METHODS
  This is a retrospective study conducted at the Hospital René Huguenin of the Institut Curie (Paris, France). It includes 327 prostheses, from 268 patients who underwent surgery for breast reconstruction between February 2008 and February 2012: 69 PIP(®) (Group 1), 82 Mentor(®) (Group 2) and 179 Allergan(®) (Group 3). The objective of the study was to compare the rates of early and late complications for each prosthesis. Our results are compared with the current literature.
  
  
  RESULTS
  With regard to the rate of early complications (hematoma, infection, seroma, wound dehiscence), no difference was observed between the three groups (P not significant). However, the study found that 100% of the 13 PIP(®) implants with early complications required surgical revision. There were too few late complications (capsular contracture, prosthetic rupture) in our cohort to allow statistical comparison between the three groups (P not significant). We compare our results with the current literature.
  
  
  CONCLUSIONS
  This study highlights the lack of significant difference in the occurrence of early adverse events between the three groups of implants. This may explain the time taken for surgeons to become aware there was a problem with the PIP(®) implants. The low rate of late complications in our series does not allow statistical analysis between the three groups of implants.
authors.affiliation: Service de chirurgie reconstructrice, hôpital René-Huguenin, institut Curie, 35, rue Dailly, 92210 Saint-Cloud, France; Service de chirurgie plastique, hôpital Saint-Joseph, 185, rue Raymond-Losserand, 75014 Paris, France. Electronic address: claire.fenoll@gmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Fenoll
authors.affiliation: Service de chirurgie plastique reconstructrice et esthétique, chirurgie de la main, chirurgie de réassignation sexuelle, centre François-Michelet, CHU de Pellegrin Bordeaux, 33000 Bordeaux, France; Laboratoire d'anatomie, université de Bordeaux, 33000 Bordeaux, France. Electronic address: franckleclere@yahoo.fr.
authors.forename: F M
authors.initials: FM
authors.lastname: Leclère
authors.affiliation: Service de chirurgie plastique reconstructrice et esthétique, HEGP, 20, rue Leblanc, 75015 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Hivelin
authors.affiliation: Chirurgie plastique reconstructrice et esthétique, CHU Tenon, 75020 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Atlan
authors.affiliation: Service de chirurgie reconstructrice, hôpital René-Huguenin, institut Curie, 35, rue Dailly, 92210 Saint-Cloud, France.
authors.forename: I
authors.initials: I
authors.lastname: Cothier-Savey
authors.affiliation: Service de chirurgie plastique reconstructrice et esthétique, HEGP, 20, rue Leblanc, 75015 Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Lantieri
authors.affiliation: Service de chirurgie reconstructrice, hôpital René-Huguenin, institut Curie, 35, rue Dailly, 92210 Saint-Cloud, France.
authors.forename: P
authors.initials: P
authors.lastname: Le Masurier
mesh_terms: D000328:Adult; D000368:Aged; D018427:Breast Implants / Q000009:adverse effects* / Q000706:statistics & numerical data; D005260:Female; D005602:France; D006801:Humans; D016462:Mammaplasty; D008875:Middle Aged; D011183:Postoperative Complications; D011475:Prosthesis Failure; D012086:Reoperation; D012189:Retrospective Studies; D057053:Safety-Based Medical Device Withdrawals
keywords: Breast implant; Breast reconstruction; Complication précoce; Early complication; Implant mammaire; Infection; PIP(®); Reconstruction mammaire; Reprise chirurgicale; Revision surgery