title: Retinal Disease in Marfan Syndrome: From the Marfan Eye Consortium of Chicago.
abstract: OBJECTIVE
  To study the prevalence of peripheral retinal disease in patients with Marfan Syndrome (MFS).
  
  
  METHODS
  In this observational, cross-sectional case series, patients with MFS were recruited by the Marfan Eye Consortium of Chicago during the National Marfan Foundation's annual conference. Patients underwent a fully dilated exam by vitreoretinal specialists in addition to ultra-widefield fundus photography using a scanning laser ophthalmoscope (Optos 200Tx; Optos PLC, Dunfermline, Scotland, United Kingdom).
  
  
  RESULTS
  Clinical examination revealed posterior segment pathology in 18% of eyes with increased incidence to 70% in patients with a subluxed lens. In six out of 10 subjects in whom the clinical exam was suboptimal (young age, small pupil, and limited cooperation), the Optos provided a superior view of the peripheral retina compared to clinical exam alone.
  
  
  CONCLUSIONS
  Clinical exam of MFS patients revealed similar posterior segment pathology as noted in previous literature, with improved detection of peripheral retinal disease with the use of ultra-widefield imaging.
authors.forename: Safa
authors.initials: S
authors.lastname: Rahmani
authors.forename: Alice T
authors.initials: AT
authors.lastname: Lyon
authors.forename: Amani A
authors.initials: AA
authors.lastname: Fawzi
authors.forename: Irene H
authors.initials: IH
authors.lastname: Maumenee
authors.forename: Marilyn B
authors.initials: MB
authors.lastname: Mets
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D006801:Humans; D007906:Lens Subluxation / Q000175:diagnosis / Q000209:etiology; D008382:Marfan Syndrome / Q000150:complications*; D008875:Middle Aged; D009887:Ophthalmoscopy; D010781:Photography; D015995:Prevalence; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology; D012164:Retinal Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*