title: Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins.
abstract: Juvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not well-understood. In this review, we highlight recent advances which demonstrate the importance of transcription factors from the bHLH-PAS and nuclear receptor families in mediating the response to JH.
authors.affiliation: Department of Biology, Fordham University, Bronx, NY 10458, USA. tbernardo@fordham.edu.
authors.forename: Travis J
authors.initials: TJ
authors.lastname: Bernardo
authors.affiliation: Department of Biology, Fordham University, Bronx, NY 10458, USA. dubrovsky@fordham.edu.|Center for Cancer, Genetic Diseases, and Gene Regulation, Fordham University, Bronx, NY 10458, USA. dubrovsky@fordham.edu.
authors.forename: Edward B
authors.initials: EB
authors.lastname: Dubrovsky
keywords: Drosophila melanogaster; bHLH-PAS; germ cell-expressed; juvenile hormone; methoprene-tolerant; nuclear receptor