title: Physical Activity, Aerobic Capacity, and Total Antioxidant Capacity in Healthy Men and in Men with Coronary Heart Disease.
abstract: OBJECTIVE
  The purpose of the study was to assess total antioxidant capacity (TAC) of blood serum in relation with habitual leisure time physical activity (LTPA) and aerobic capacity in a group of 90 men with coronary heart disease (CHD) aged 34.8-77.0 years and in 90 age-matched peers without CHD.
  
  
  METHODS
  Two spectrophotometric methods were applied to assess TAC: Ferric Reducing Ability of Serum (TAC-FRAS) and 2.2-diphenyl-1-picryl-hydrazyl (TAC-DPPH) tests. Aerobic capacity was expressed as physical working capacity at 85% of the maximal heart rate (PWC(85%HRmax)).
  
  
  RESULTS
  CHD patients had higher values of TACFRAS (1.37 ± 0.28 versus 1.27 ± 0.23 mmol FeCl2·L(-1); P < 0.05) but there were no group differences for TAC-DPPH and for uric acid (UA). Negative correlation was found between LTPA (also when calculated per kg of body mass) and TAC-DPPH in CHD patients. In CHD patients, TAC-FRAS and UA were lower in subjects with higher aerobic capacity expressed as PWC(85%HRmax/kg). Those associations were not found in healthy men.
  
  
  CONCLUSIONS
  We conclude that TAC of blood serum is moderately adversely related to LTPA and aerobic capacity in patients with CHD. UA, as the main determinant of serum TAC, may be partially responsible for those associations.
authors.affiliation: Department of Geriatrics, Medical University of Lodz, Plac Hallera 1, 90-647 Lodz, Poland ; Department of Preventive Medicine, Medical University of Lodz, Żeligowskiego Street 7/9, 90-752 Lodz, Poland ; Department of Hygiene and Health Promotion, Medical University of Lodz, Jaracza Street 63, 90-251 Lodz, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Gawron-Skarbek
authors.affiliation: Department of Geriatrics, Medical University of Lodz, Plac Hallera 1, 90-647 Lodz, Poland ; Department of Preventive Medicine, Medical University of Lodz, Żeligowskiego Street 7/9, 90-752 Lodz, Poland ; Cardiac Rehabilitation Centre, Copernicus Memorial Hospital, Popioły Street 40, 93-438 Lodz, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Chrzczanowicz
authors.affiliation: Department of Physical Medicine, Medical University of Lodz, Plac Hallera 1, 90-647 Lodz, Poland.
authors.forename: Joanna
authors.initials: J
authors.lastname: Kostka
authors.affiliation: Department of Clinical Physiology, Medical University of Lodz, Mazowiecka Street 6/8, 92-215 Lodz, Poland.
authors.forename: Dariusz
authors.initials: D
authors.lastname: Nowak
authors.affiliation: Department of Preventive Medicine, Medical University of Lodz, Żeligowskiego Street 7/9, 90-752 Lodz, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Drygas
authors.affiliation: Department of Sports Medicine, Medical University of Lodz, Pomorska Street 251, 92-213 Lodz, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Jegier
authors.affiliation: Department of Geriatrics, Medical University of Lodz, Plac Hallera 1, 90-647 Lodz, Poland ; Department of Preventive Medicine, Medical University of Lodz, Żeligowskiego Street 7/9, 90-752 Lodz, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Kostka
mesh_terms: D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000737:chemistry*; D003324:Coronary Artery Disease / Q000534:rehabilitation*; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D012307:Risk Factors
chemical_list: D000975:Antioxidants