title: Effectiveness of Hexetidine 0.1% Compared to Chlorhexidine Digluconate 0.12% in Eliminating Candida Albicans Colonizing Dentures: A Randomized Clinical In Vivo Study.
abstract: BACKGROUND
  Denture hygiene is an important factor in the prevention and treatment of denture stomatitis (DS). This study aimed to evaluate the efficacy of two different mouthwashes (chlorhexidine digluconate 0.12% and hexetidine 0.1%) in eliminating Candida albicans on dentures.
  
  
  METHODS
  A total of 60 denture wearers (20 men, 40 women; age range 40-80 years) with clinical evidence of DS were randomly divided into 2 test groups and 1 control group. The dentures of each test group were treated by immersion in one of the two mouthwashes while those of the control group were immersed in distilled water. Swab samples from the palatal surfaces of the upper dentures were collected before and after of cleaner use and examined mycologically.
  
  
  RESULTS
  Reduction in the number of colony-forming units of Candida albicans after immersion of the dentures with chlorhexidine digluconate 0.12% was significantly greater than that of the group using hexetidine 0.1% and those of the control group.
  
  
  CONCLUSIONS
  Hexetidine 0.1% solution tested for the first time as a product of disinfection of the acrylic dentures showed average results after immersion of 8 night hours for 4 days and was less effective than chlorhexidine digluconate 0.12%.
authors.affiliation: Assistant Professor, Department of Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon.
authors.forename: Georges
authors.initials: G
authors.lastname: Aoun
authors.affiliation: Chief of Clinical Services, Department of Orthodontics, School of Dentistry, Lebanese University, Beirut, Lebanon ; Clinical Associate, Department of Orthodontics and Dentofacial Orthopedics, American University of Beirut, Lebanon.
authors.forename: Maria
authors.initials: M
authors.lastname: Saadeh
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Lebanese University, Beirut, Lebanon.
authors.forename: Antoine
authors.initials: A
authors.lastname: Berberi
keywords: Candida albicans; chlorhexidine digluconate; denture stomatitis; hexetidine