title: Modification of carbon paste electrode with Fe(III)-clinoptilolite nano-particles for simultaneous voltammetric determination of acetaminophen and ascorbic acid.
abstract: A novel carbon paste electrode (CPE) modified with Fe(III)-exchanged clinoptilolite nano-particles (Fe(III)-NClino/CPE) was constructed and used for simultaneous voltammetric (CV, SqW and chronoamperometry) determination of ascorbic acid and acetaminophen. Raw and modified zeolites were characterized by X-ray diffraction (XRD) and transmission electron microscope (TEM). The square wave peak current was linearly increased in the concentration ranges of 1.0 × 10(-9)-1.0 × 10(-2) mol L(-1) for ascorbic acid and 1.0 × 10(-10-)1.0 × 10(-2) mol L(-1) for acetaminophen with detection limits of 1.8 × 10(-9) mol L(-1) and 9.9 × 10(-10) mol L(-1), respectively. The detection limits of 2.4 × 10(-10) mol L(-1) and 2.5 × 10(-11) mol L(-1) were also obtained for AA and AC in chronoamperometric measurements, respectively. The diffusion coefficients of 7.5 × 10(-5) cm(2) s(-1) and 2.4 × 10(-5) cm(2) s(-1) were respectively calculated for the oxidation of AC and AA by chronoamperometry. The proposed electrode exhibited high sensitivity and good stability, and would be valuable for the clinical assay of ascorbic acid and acetaminophen.
authors.affiliation: Department of Chemistry, Shahreza Branch, Islamic Azad University, P.O. Box 311-86145, Shahreza, Isfahan, Iran; Young Researchers and Elite Club, Shahreza Branch, Islamic Azad University, Shahreza, Iran.
authors.forename: Samira
authors.initials: S
authors.lastname: Sharifian
authors.affiliation: Department of Chemistry, Shahreza Branch, Islamic Azad University, P.O. Box 311-86145, Shahreza, Isfahan, Iran; Young Researchers and Elite Club, Shahreza Branch, Islamic Azad University, Shahreza, Iran; Razi Chemistry Research Center (RCRC), Shahreza Branch, Islamic Azad University, Isfahan, Iran. Electronic address: arnezamzadeh@iaush.ac.ir.
authors.forename: Alireza
authors.initials: A
authors.lastname: Nezamzadeh-Ejhieh
mesh_terms: D000082:Acetaminophen / Q000032:analysis*; D001205:Ascorbic Acid / Q000032:analysis*; D002244:Carbon / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D004573:Electrolytes / Q000737:chemistry; D005290:Ferric Compounds / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007477:Ions; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010084:Oxidation-Reduction; D014961:X-Ray Diffraction; D017641:Zeolites / Q000737:chemistry*
chemical_list: D004573:Electrolytes; D005290:Ferric Compounds; D007477:Ions; C083175:clinoptilolite; D017641:Zeolites; D000082:Acetaminophen; D002244:Carbon; D001205:Ascorbic Acid
keywords: Acetaminophen; Ascorbic acid; Clinoptilolite; Nano; Voltammetry