title: A comparison of PGC-1α mRNA and protein expression in response to 1-week endurance training on alternate days or 4 consecutive days.
abstract: To understand the molecular mechanisms of adaptation to different training protocols, this study compared the effects of 4 sessions of 90 min treadmill exercise on alternate days or consecutive days in 1 week on messenger RNA (mRNA) and protein expression of proliferator-activated receptor-γ coactivator 1-α in rat gastrocnemius muscle. The mRNA significantly increased by 25.8-fold after alternate-day and 10.1-fold after consecutive-day training, while the protein showed no significant cumulative effect, 1.5-1.7-fold above baseline, in the 2 protocols.
authors.affiliation: a Department of Health and Exercise Science, Tianjin University of Sport, Tianjin 300381, China.
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Huang
authors.affiliation: a Department of Health and Exercise Science, Tianjin University of Sport, Tianjin 300381, China.
authors.forename: Min
authors.initials: M
authors.lastname: Yao
authors.affiliation: a Department of Health and Exercise Science, Tianjin University of Sport, Tianjin 300381, China.
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Wang
authors.affiliation: b School of Health and Human Sciences, Southern Cross University, P.O. Box 157, Lismore, NSW 2480, Australia.
authors.forename: Allan
authors.initials: A
authors.lastname: Davie
authors.affiliation: b School of Health and Human Sciences, Southern Cross University, P.O. Box 157, Lismore, NSW 2480, Australia.
authors.forename: Shi
authors.initials: S
authors.lastname: Zhou
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D008297:Male; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000378:metabolism*; D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; D010807:Physical Endurance; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D017207:Rats, Sprague-Dawley; D012420:Running; D013997:Time Factors; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D015854:Up-Regulation
chemical_list: D000071248:Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; C501429:Ppargc1a protein, rat; D012333:RNA, Messenger; D014157:Transcription Factors
keywords: ARNm; PGC-1α; endurance training; entraînement en endurance; gastrocnemius; mRNA; muscle gastrocnémien; protein; protéine; recovery; récupération