title: [IMMUNOLOGIC MONITORING OF HELICOBACTER PYLORI PERSISTENCE IN THE ORGANISM].
abstract: Generalized results of 15-year prospective studies of frequency of occurrence and dynamics of circulation of pathogenetically significant LPS/O-antigens, high molecular weight proteins, including CagA, and VacA of Helicobacter pylori in biological media of organism in patients with gastrointestinal diseases and asymptomatic volunteers due to effects of external and internal factors are presented. Features of antigen circulation and reciprocal immune reaction of the organism are established, that reflect their interaction in the parasite-host tandem, risk and prognosis of possible complications in the process of long-term persistence of Helicobacter pylori in the organism.
authors.forename: Yu A
authors.initials: YA
authors.lastname: Belaya
authors.forename: O F
authors.initials: OF
authors.lastname: Belaya
authors.forename: V G
authors.initials: VG
authors.lastname: Petrukhin
authors.forename: M S
authors.initials: MS
authors.lastname: Vakhrameeva
authors.forename: S M
authors.initials: SM
authors.lastname: Bystrova
authors.forename: A V
authors.initials: AV
authors.lastname: Pronin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000942:Antigens, Bacterial / Q000276:immunology; D001426:Bacterial Proteins / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D016481:Helicobacter Infections / Q000276:immunology*; D016480:Helicobacter pylori / Q000502:physiology*; D054884:Host-Pathogen Interactions / Q000276:immunology*; D006801:Humans; D007157:Immunologic Surveillance; D007223:Infant; D008297:Male; D008875:Middle Aged; D019081:O Antigens / Q000276:immunology; D011446:Prospective Studies
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D019081:O Antigens; C074689:VacA protein, Helicobacter pylori; C080866:cagA protein, Helicobacter pylori