title: Access to Polyfunctionalized Chiral Piperidines through Enantioselective Addition-Carbocyclization Cascade Reaction Catalyzed by a Rhodium(I)-Diene Complex.
abstract: A new addition-carbocyclization cascade reaction initiated by arylboronic acids and catalyzed by a rhodium/chiral diene complex is described. Starting from N-bridged oxoenoate derivatives, highly functionalized piperidines bearing three contiguous stereogenic centers were obtained with excellent enantio- and diastereoselectivities.
authors.affiliation: PSL Research University , Chimie ParisTech - CNRS, Institut de Recherche de Chimie Paris, 11 rue Pierre et Marie Curie, 75005, Paris, France.
authors.forename: Fabien
authors.initials: F
authors.lastname: Serpier
authors.affiliation: Diverchim, ZAC du Moulin, 6 rue du Noyer, 95700 Roissy-en-France, France.
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Brayer
authors.affiliation: Diverchim, ZAC du Moulin, 6 rue du Noyer, 95700 Roissy-en-France, France.
authors.forename: Benoît
authors.initials: B
authors.lastname: Folléas
authors.affiliation: PSL Research University , Chimie ParisTech - CNRS, Institut de Recherche de Chimie Paris, 11 rue Pierre et Marie Curie, 75005, Paris, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Darses