title: Overview of Immunodeficiency Disorders.
abstract: The spectrum of primary immunodeficiency disorders (PIDs) is expanding. It includes typical disorders that primarily present with defective immunity as well as disorders that predominantly involve other systems and show few features of impaired immunity. The rapidly growing list of new immunodeficiency disorders and treatment modalities makes it imperative for providers to stay abreast of the latest and best management strategies. This article presents a brief overview of recent clinical advances in PIDs.
authors.affiliation: Children's Mercy Hospital, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA. Electronic address: nraje@cmh.edu.
authors.forename: Nikita
authors.initials: N
authors.lastname: Raje
authors.affiliation: Children's Mercy Hospital, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA.
authors.forename: Chitra
authors.initials: C
authors.lastname: Dinakar
mesh_terms: D000818:Animals; D015551:Autoimmunity; D006801:Humans; D007109:Immunity; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D011379:Prognosis; D015398:Signal Transduction
keywords: Antibody deficiency; Autoimmunity; Immune defect; Immune dysregulation; Immunodeficiency; Innate immune defect; Lymphoproliferation