title: Evaluation of Dentifrice Containing Nano-hydroxyapatite for Dentinal Hypersensitivity: A Randomized Controlled Trial.
abstract: BACKGROUND
  This randomized, double-blind, parallel arm study was carried out to evaluate and compare the effectiveness between nano-hydroxyapatite (HAP) and a benchmark dentifrice in reducing dentin hypersensitivity.
  
  
  METHODS
  About 36 patients were selected, randomly divided into two groups and was evaluated clinically using three different stimuli, i.e., tactile, air blast, and cold water test. The patient's responses to various stimuli were recorded using a visual analog scale at baseline and after 4 weeks.
  
  
  RESULTS
  Statistical analysis was done using unpaired and paired t-tests. It was seen that patients treated in both groups showed significant reductions scores across all sensitivity measures at the end of 4 weeks.
  
  
  CONCLUSIONS
  The HAP containing toothpaste was effective in reducing dentin hypersensitivity with pre-existing benchmark toothpaste tested and hence can be advocated in the management of hypersensitivity.
authors.affiliation: Senior Lecturer, Department of Public Health Dentistry, Madha Dental College & Hospital, Chennai, Tamil Nadu, India.
authors.forename: Nithin Manchery
authors.initials: NM
authors.lastname: Gopinath
authors.affiliation: Professor and Head, Department of Public Health Dentistry, Saveetha Dental College & Hospital, Chennai, Tamil Nadu, India.
authors.forename: Joseph
authors.initials: J
authors.lastname: John
authors.affiliation: Senior Lecturer, Department of Public Health Dentistry, Chettinad Dental College & Research Institute, Kelambakkam, Kancheepuram, Tamil Nadu, India.
authors.forename: N
authors.initials: N
authors.lastname: Nagappan
authors.affiliation: Senior Lecturer, Department of Public Health Dentistry, Chettinad Dental College & Research Institute, Kelambakkam, Kancheepuram, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Prabhu
authors.affiliation: Senior Lecturer, Department of Public Health Dentistry, Madha Dental College & Hospital, Chennai, Tamil Nadu, India.
authors.forename: E Senthil
authors.initials: ES
authors.lastname: Kumar
keywords: Clinical trials; NovaMin; dentinal hypersensitivity; hypersensitivity; nano-hydroxyapatite