title: Evaluation of a Web-based tailored intervention (TAVIE en santé) to support people living with HIV in the adoption of health promoting behaviours: an online randomized controlled trial protocol.
abstract: BACKGROUND
  Long-term use of antiretroviral therapy, normal aging, and presence of certain risk factors are associated with metabolic disorders that predispose persons living with HIV to diabetes and cardiovascular diseases. The emergence and progression of these disorders can be prevented by adopting healthy behaviours. Based on the theory of planned behaviour, the Web-based tailored intervention TAVIE en santé was developed. The aim of this study is to evaluate the effectiveness of TAVIE en santé in order to support people living with HIV in the adoption of health promoting behaviours.
  
  
  METHODS
  An online randomized controlled trial with parallel-groups will be conducted across Canada. To participate in this study, people living with HIV must be: ≥ 18 years, able to read/understand French or English, have access to the Internet. A convenience sample of 750 participants will be randomly assigned either to an experimental group (TAVIE en santé, n = 375) or to a control group (websites, n = 375) (1:1 allocation ratio). The TAVIE en santé intervention is composed of seven interactive computer sessions, lasting between 5 and 10 min. The sessions, hosted by a virtual nurse, aim to develop and strengthen skills required for behaviour change. The control group will receive a validated list of five predetermined conventional health-related Websites. The adoption of health behaviour (smoking cessation or physical activity or healthy eating) is the principal outcome. Cognitions (intention, attitude, perceived behavioral control) are the secondary outcomes. Health indicators will also be assessed. All outcomes will be measured with a self-administered online questionnaire and collected three times: at baseline, 3 and 6 months after. The principal analyses will focus on differences between the two trial groups using Intention-to-Treat analysis.
  
  
  CONCLUSIONS
  This study will yield new results about the efficacy of Web-based tailored health behaviours change interventions in the context of chronic disease. The TAVIE en santé intervention could constitute an accessible complementary service in support of existing specialized services to support people living with HIV adopt health behaviors.
  
  
  BACKGROUND
  NCT02378766 , assigned on March 3th 2015.
authors.affiliation: Research Centre of the Centre Hospitalier de l'Université de Montréal, 900 Saint Denis Street, Montreal, H2X 0A9, QC, Canada. jose.cote@umontreal.ca.|Research Chair in Innovative Nursing Practices, 900 Saint Denis Street, Montreal, H2X 0A9, QC, Canada. jose.cote@umontreal.ca.|Faculty of Nursing, Université de Montréal, 2375, chemin de la Côte-Ste-Catherine, Montréal, H3T 1A8, QC, Canada. jose.cote@umontreal.ca.
authors.forename: José
authors.initials: J
authors.lastname: Côté
authors.affiliation: Faculty of Nursing, Université de Montréal, 2375, chemin de la Côte-Ste-Catherine, Montréal, H3T 1A8, QC, Canada. sylvie.cossette.inf@umontreal.ca.|Research Center of the Montreal Heart Institute, 5000, Bélanger Street, Montréal, H1T 1C8, QC, Canada. sylvie.cossette.inf@umontreal.ca.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Cossette
authors.affiliation: Faculty of Nursing, Université de Montréal, 2375, chemin de la Côte-Ste-Catherine, Montréal, H3T 1A8, QC, Canada. pilar.ramirez.garcia@umontreal.ca.
authors.forename: Pilar
authors.initials: P
authors.lastname: Ramirez-Garcia
authors.affiliation: Faculty of Medecine, McGill University, 3655 Sir William Osler, Montreal, H3G 1Y6, QC, Canada. alexandra.depokomandy@mcgill.ca.
authors.forename: Alexandra
authors.initials: A
authors.lastname: De Pokomandy
authors.affiliation: Faculty of Human and Social Development, University of Victoria, 3800 Finnerty Road, Victoria, V8P 5C2, BC, Canada. worthing@uvic.ca.
authors.forename: Catherine
authors.initials: C
authors.lastname: Worthington
authors.affiliation: Research Centre of the Centre Hospitalier Universitaire de Québec, 2705, boulevard Laurier, Québec, G1V 4G2, QC, Canada. marie-pierre.gagnon@fsi.ulaval.ca.|Faculty of Nursing Sciences, Université Laval, 1050, avenue de la Médecine Local 3645, Québec, G1V 0A6, QC, Canada. marie-pierre.gagnon@fsi.ulaval.ca.
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: Gagnon
authors.affiliation: Research Centre of the Centre Hospitalier de l'Université de Montréal, 900 Saint Denis Street, Montreal, H2X 0A9, QC, Canada. patricia.auger.chum@ssss.gouv.qc.ca.|Research Chair in Innovative Nursing Practices, 900 Saint Denis Street, Montreal, H2X 0A9, QC, Canada. patricia.auger.chum@ssss.gouv.qc.ca.
authors.forename: Patricia
authors.initials: P
authors.lastname: Auger
authors.affiliation: Faculty of Nursing, Université du Québec à Trois-Rivièves, 3351, boul. des Forges, CP 500, Trois-Rivières, G9A 5H7, QC, Canada. francois.boudreau@uqtr.ca.
authors.forename: François
authors.initials: F
authors.lastname: Boudreau
authors.affiliation: Ryerson University, 350 Victoria Street, Toronto, M5B 2K3, ON, Canada. joyal.miranda@ryerson.ca.
authors.forename: Joyal
authors.initials: J
authors.lastname: Miranda
authors.affiliation: Canada Research Chair on Software Patterns and Patterns of Software, 2500, chemin de Polytechnique, Montréal, H3T 1J4, QC, Canada. yann-gael.gueheneuc@polymtl.ca.|Department of Computer Engineering, Polytechnique Montréal, 2500, chemin de Polytechnique, Montréal, H3T 1J4, QC, Canada. yann-gael.gueheneuc@polymtl.ca.
authors.forename: Yann-Gaël
authors.initials: YG
authors.lastname: Guéhéneuc
authors.affiliation: Research Centre of the Centre Hospitalier de l'Université de Montréal, 900 Saint Denis Street, Montreal, H2X 0A9, QC, Canada. cecile.tremblay@inspq.qc.ca.|Quebec Public Health Laboratory, Sainte-Marie Rd, Sainte-Anne-de-Bellevue, H9X 3R5, QC, Canada. cecile.tremblay@inspq.qc.ca.|Faculty of Medecine, Université de Montréal, 2900, boulevard Édouard-Montpetit, Montréal, H3T 1J4, QC, Canada. cecile.tremblay@inspq.qc.ca.
authors.forename: Cécile
authors.initials: C
authors.lastname: Tremblay
mesh_terms: D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000627:therapeutic use; D002170:Canada; D004360:Drug Therapy, Computer-Assisted / Q000379:methods*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000451:nursing* / Q000517:prevention & control*; D006266:Health Education / Q000379:methods*; D006801:Humans; D020407:Internet / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D012107:Research Design; D012648:Self Care / Q000379:methods; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents