title: Epidemiology, Clinical Features, and Prescribing Patterns of Aortic Aneurysm in Asian Population From 2005 to 2011.
abstract: Aortic aneurysm (AA) is a leading cause of death in Asia and the world. The prevalence in Western countries is around 1.3% to 8%. However, it is still unclear about the incidence, prevalence, and mortality of AA in Asian population. The aim of this study is to investigate the epidemiology of AA for all subtypes in Taiwan, and describe the clinical features and prescribing patterns for AA population.A population-based study was conducted using information from National Health Insurance Research Database (NHIRD) in Taiwan. Patients who were diagnosed with AA and also received computed tomography (CT) were included in this study. Incidence, prevalence, and mortality were calculated in each year during 2005 to 2011. Prevalent comorbidities and prescribing patterns were both evaluated among study population.The average annual incidence of AA in Taiwan was 7.35 per 100,000 population, and the prevalence was 29.04 per 100,000 population. It showed an increased trend of incidence from 2005 to 2011, so as prevalence and mortality. The incidence was associated with age and sex difference. It was much higher in those older than 65 years, especially for male. Hypertension, coronary artery disease (CAD), and chronic obstructive pulmonary disease (COPD) were prevalent comorbidities. Eighty-eight percentages of patients were prescribed antihypertensive agents in acute phase, where 61.4% of calcium channel blocker (CCB) was the most one.Our study found that incidence of AA was lower in Taiwan than in other countries. Nevertheless, it showed an increased trend of AA disease for incidence, prevalence, and also mortality during 2005 to 2011.
authors.affiliation: From the School of Pharmacy, Master Program in Clinical Pharmacy, Kaohsiung Medical University (S-WW, Y-BH, C-YC); Department of Pharmacy (Y-BH, C-YC); Department of Surgery, Division of Cardiovascular surgery (J-WH, C-CC); and Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan (W-TL).
authors.forename: Shih-Wei
authors.initials: SW
authors.lastname: Wang
authors.forename: Yaw-Bin
authors.initials: YB
authors.lastname: Huang
authors.forename: Jiann-Woei
authors.initials: JW
authors.lastname: Huang
authors.forename: Chaw-Chi
authors.initials: CC
authors.lastname: Chiu
authors.forename: Wen-Ter
authors.initials: WT
authors.lastname: Lai
authors.forename: Chung-Yu
authors.initials: CY
authors.lastname: Chen
mesh_terms: D000367:Age Factors; D000368:Aged; D001014:Aortic Aneurysm / Q000188:drug therapy* / Q000453:epidemiology* / Q000401:mortality; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D015995:Prevalence; D012737:Sex Factors; D013624:Taiwan / Q000453:epidemiology