title: [Causes of failure after total knee arthroplasty].
abstract: OBJECTIVE
  To identify the causes of failure after total knee arthroplasty (TKA).
  
  
  METHODS
  Retrospective reviews were conducted for the causes of failures of 181 TKA patients between January 2007 and December 2013.
  
  
  RESULTS
  Among the causes of failures after primary TKA, infection was the major cause of failure (53%, 96/181) followed by aseptic loosening (16%, 29/181), arthrofibrosis (10%, 18/181), instability (6.6%, 12/181), extensor mechanism problem (5%, 9/181), wear (4.4%, 8/181), periprosthetic fracture (2.8%, 5/181) and others (2.2%, 4/181). And 64.1% occurred in the first two years, 19.9% occurred between 2 and 5 years and 16.0% occurred after 5 years after operation. Up to 84.0% occurred in 5 years.
  
  
  CONCLUSIONS
  The top three causes of failures after primary TKA at our center are infection, aseptic loosening and arthrofibrosis.
authors.affiliation: Department of Orthopedics, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Ziqiang
authors.initials: Z
authors.lastname: Huang
authors.affiliation: Department of Orthopedic, Beijing Tsinghua Changgeng Hospital, Medical Center, Tsinghua University, Beijing 100044, China; Email: suncjdoctor@163.com.
authors.forename: Changjiao
authors.initials: C
authors.lastname: Sun
mesh_terms: D019645:Arthroplasty, Replacement, Knee; D006801:Humans; D057068:Periprosthetic Fractures; D011475:Prosthesis Failure; D012189:Retrospective Studies