title: Diagnostic Accuracy of Neutrophil/Lymphocyte Ratio, Red Cell Distribution Width and Platelet Distribution Width in Ovarian Torsion.
abstract: The main aim of this diagnostic case-control study of 136 patients with ovarian cysts (44 patients with ovarian torsion and 92 controls) was to determine the diagnostic value of haematologic inflammatory markers (neutrophil/lymphocyte ratio [NLR], red cell distribution width [RDW] and platelet distribution width [PDW]) for torsioned ovarian cysts. The presence of a torsioned ovarian cyst was identified by a 1.18-fold increase in the NLR (95%CI: 1.04-1.34, P = 0.009), a 1.22-fold increase in the RDW (95%CI: 1.04-1.43, P = 0.023) and a 1.93-fold increase in the PDW (95%CI: 1.19-3.14, P = 0.007). The NLR was the best predictor of a torsioned ovarian cyst (AUC: 0.74; 95% CI: 0.68-0.83). When an NLR cut-off value of 2.44 was used to determine ovarian torsion, the sensitivity, specificity, + LR and -LR were 70.5%, 70.7%, 2.40 and 0.42, respectively. In conclusion, the NLR may have diagnostic and prognostic value in determining torsioned ovarian cysts.
authors.affiliation: a Department of Obstetrics and Gynecology , Ataturk University, Faculty of Medicine , Erzurum , Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Yilmaz
authors.affiliation: b Department of Obstetrics and Gynecology , Nene Hatun Obstetrics and Gynecology Hospital , Erzurum , Turkey.
authors.forename: G
authors.initials: G
authors.lastname: Cimilli
authors.affiliation: c Department of Emergency , Ataturk University, Faculty of Medicine , Erzurum , Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Saritemur
authors.affiliation: d Department of Internal Medicine , Cagri Medical Center , Elazıg , Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Demircan
authors.affiliation: b Department of Obstetrics and Gynecology , Nene Hatun Obstetrics and Gynecology Hospital , Erzurum , Turkey.
authors.forename: U
authors.initials: U
authors.lastname: Isaoglu
authors.affiliation: e Department of General Surgery , Ataturk University Faculty of Medicine , Erzurum , Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Kisaoglu
authors.affiliation: c Department of Emergency , Ataturk University, Faculty of Medicine , Erzurum , Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Emet
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001792:Blood Platelets; D016022:Case-Control Studies; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D018655:Lymphocyte Count; D008214:Lymphocytes; D008875:Middle Aged; D009504:Neutrophils; D010048:Ovarian Cysts / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014102:Torsion Abnormality / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D055815:Young Adult
chemical_list: D015415:Biomarkers
keywords: Torsioned ovarian cyst; diagnosis; haematologic inflammatory markers; neutrophil/lymphocyte ratio; platelet distribution width; red cell distribution width