title: Late-Onset Hypogonadism and Testosterone Replacement in Older Men.
abstract: Late-onset hypogonadism is an underdiagnosed and easily treated condition defined by low serum testosterone levels in men older than 65 years. When treated, a significant improvement in quality of life may be reached in this rapidly rising sector of the population. During the evaluation, laboratory tests and a full medication review should be performed to exclude other illnesses or adverse effects from medications. The major goal of treatment in this population is treating the symptoms related to hypogonadism. There has not been clear evidence supporting universally giving older men with low serum testosterone levels and hypogonadal symptoms testosterone replacement therapy.
authors.affiliation: Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Kansas School of Medicine, 4023 Wescoe, Mailstop 2024, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA. Electronic address: rbhattacharya@kumc.edu.
authors.forename: Rajib K
authors.initials: RK
authors.lastname: Bhattacharya
authors.affiliation: Department of Family Medicine, Division of Geriatric Medicine, University of Kansas School of Medicine, 3901 Rainbow Boulevard, Kansas City, KS 66160, USA.
authors.forename: Shelley B
authors.initials: SB
authors.lastname: Bhattacharya
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D017668:Age of Onset; D000368:Aged; D015415:Biomarkers / Q000097:blood; D020249:Hormone Replacement Therapy; D006801:Humans; D007006:Hypogonadism / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D011788:Quality of Life; D013739:Testosterone / Q000008:administration & dosage* / Q000097:blood* / Q000172:deficiency; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D013739:Testosterone
keywords: Geriatric; Hypogonadism; Management; Osteoporosis; Testosterone; Treatment