title: OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN RETINAL ARTERY OCCLUSION.
abstract: OBJECTIVE
  To describe the retinal microvasculature of the eyes with nonarteritic retinal artery occlusion (RAO) based on optical coherence tomography angiography.
  
  
  METHODS
  Cross-sectional, prospective, observational study performed from September 2014 through February 2015. En face projection of optical coherence tomography angiography images centered at the macula and optic disk of the eyes presenting with RAO were acquired using the RTVue XR Avanti with AngioVue software. Qualitative analysis of the morphology of the superficial and deep retinal capillary plexuses, and radial peripapillary capillaries was performed. Retinal vasculature images using optical coherence tomography angiography were correlated with fluorescein angiography images.
  
  
  RESULTS
  Seven patients (seven eyes) were enrolled in the study, including three eyes with central RAO and four eyes with branch RAO. Distinct differences in the distribution of zones of decreased vascular perfusion between the superficial and deep retinal capillary plexus corresponding to areas of delayed dye perfusion on fluorescein angiography were demonstrated in 6 of 7 (86.5%) eyes.
  
  
  CONCLUSIONS
  This small series suggests that optical coherence tomography angiography imaging can accurately discern retinal capillary plexuses at different levels in the eyes with RAO and may be sensitive for more precisely characterizing the extent of macular ischemia and monitoring vascular flow changes during the course of the disease.
authors.affiliation: *New England Eye Center and Tufts Medical Center, Tufts University, Boston, Maryland; †CAPES Foundation, Ministry of Education of Brazil, Brasilia, DF, Brazil; ‡Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Maryland; §Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California; ¶Doheny Eye Institute, Los Angeles, California; **Stein Eye Institute, Los Angeles, California; and ††Greater Los Angeles VA Healthcare Center, Los Angeles, California.
authors.forename: Marco A
authors.initials: MA
authors.lastname: Bonini Filho
authors.forename: Mehreen
authors.initials: M
authors.lastname: Adhi
authors.forename: Talisa E
authors.initials: TE
authors.lastname: de Carlo
authors.forename: Daniela
authors.initials: D
authors.lastname: Ferrara
authors.forename: Caroline R
authors.initials: CR
authors.lastname: Baumal
authors.forename: Andre J
authors.initials: AJ
authors.lastname: Witkin
authors.forename: Elias
authors.initials: E
authors.lastname: Reichel
authors.forename: Laura
authors.initials: L
authors.lastname: Kuehlewein
authors.forename: SriniVas R
authors.initials: SR
authors.lastname: Sadda
authors.forename: David
authors.initials: D
authors.lastname: Sarraf
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
authors.forename: Nadia K
authors.initials: NK
authors.lastname: Waheed
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002196:Capillaries / Q000473:pathology; D003430:Cross-Sectional Studies; D005260:Female; D005451:Fluorescein Angiography; D005584:Fovea Centralis / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D011446:Prospective Studies; D012039:Regional Blood Flow; D015356:Retinal Artery Occlusion / Q000175:diagnosis* / Q000503:physiopathology; D012171:Retinal Vessels / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity