title: EFFECT OF FLUORIDE VARNISHES CONTAINING DIFFERENT CALCIUM PHOSPHATE SOURCES ON MINERALIZATION OF INITIAL PRIMARY ENAMEL LESIONS.
abstract: This study was conducted to evaluate the effect of fluoride varnishes containing different calcium phosphate sources on demineralization of initial primary enamel lesions. Forty-eight sound primary incisors were completely coated with nail varnish except for two 1 x 1 mm windows before being placed in demineralizing solution for 4 days. After demineralization, one of the windows in each tooth was coated with nail varnish. The teeth were randomly divided into four groups (A to D; n = 12), and then the other (exposed) window was treated with: Group A: deionized water, Group B: Duraphat® fluoride varnish, Group C: Clinpro™ White varnish and Group D: Enamel Pro® varnish. The pH-cycling regimen was carried out consisting of demineralization (6 hours) and remineralization (18 hours) for 7 days. Polarized light microscopy was used to evaluate the lesion depth initially and then after a seven-day pH cycle. Lesion depth was measured using a computerized method with the Image-Pro® Plus Program. The pair t-test was used to compare lesion depths before and after treatment. Differences in mean lesion depths among the groups were compared with the one-way ANOVA and Tukey's multiple comparison tests with 95% confidence intervals. The lesion depths had a significant difference between before and after treatment of the all groups. There was a significant increase in lesion depth in Group A compared to the other groups. No significant differences were seen among Groups B, C and D, containing fluoride and the different calcium phosphate sources in inhibiting progression of initial primary enamel lesions.
authors.forename: Praphasri
authors.initials: P
authors.lastname: Rirattanapong
authors.forename: Kadkao
authors.initials: K
authors.lastname: Vongsavan
authors.forename: Chavengkiat
authors.initials: C
authors.lastname: Saengsirinavin
authors.forename: Tuenjai
authors.initials: T
authors.lastname: Pornmahala
mesh_terms: D002130:Calcium Phosphates / Q000494:pharmacology*; D003743:Dental Enamel / Q000187:drug effects*; D005460:Fluorides, Topical / Q000494:pharmacology*; D006801:Humans; D007180:Incisor / Q000187:drug effects; D008954:Models, Biological; D012969:Sodium Fluoride / Q000494:pharmacology*; D017001:Tooth Demineralization / Q000473:pathology*
chemical_list: D002130:Calcium Phosphates; D005460:Fluorides, Topical; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride; C020243:calcium phosphate