title: [Complete Remission after Weekly Intravenous Nanoparticle Albumin-Bound Paclitaxel in Elderly Patients with Non-Small-Cell Lung Cancer].
abstract: Case 1: An 86-year-old man was diagnosed with large cell or squamous cell lung cancer of clinical Stage II A.He was administered nanoparticle albumin-bound paclitaxel(nab-PTX)as fourth-line chemotherapy after monochemotherapy with docetaxel, vinorelbine, and S-1.The patient continues to show complete remission at the 15 courses of nab-PTX.Case 2: A 79-year-old man underwent partial resection of the right lower lung, and the pathological diagnosis was large cell lung cancer of pStage I A.However, recurrence in the right lung and multiple lymph node metastases were identified 3 years after the surgery.He was administered nab-PTX as second-line chemotherapy after vinorelbine monotherapy, and he has shown complete remission for a year.Weekly intravenous nab-PTX may be useful in elderly patients with non-small-cell lung cancer.
authors.affiliation: Dept. of Pulmonary and Thoracic Surgery, National Hospital Organization, Kanagawa Hospital.
authors.forename: Yasoo
authors.initials: Y
authors.lastname: Sugiura
authors.forename: Toshinori
authors.initials: T
authors.lastname: Hashizume
authors.forename: Osamu
authors.initials: O
authors.lastname: Kawai
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Ohkubo
authors.forename: Hisae
authors.initials: H
authors.lastname: Fusegawa
authors.forename: Norihito
authors.initials: N
authors.lastname: Araki
authors.forename: Shizuka
authors.initials: S
authors.lastname: Kaseda
authors.forename: Etsuo
authors.initials: E
authors.lastname: Nemoto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000418:Albumins / Q000008:administration & dosage / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy*; D006801:Humans; D007262:Infusions, Intravenous; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D009367:Neoplasm Staging; D017239:Paclitaxel / Q000008:administration & dosage / Q000627:therapeutic use*; D012074:Remission Induction
chemical_list: C520255:130-nm albumin-bound paclitaxel; D000418:Albumins; D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel