title: Synchronous pituitary adenoma and pituicytoma.
abstract: Pituicytoma is a rare benign neoplasm arising in the sellar region, usually found in the posterior lobe and/or pituitary stalk. Here, we report the case of a 67-year-old woman who presented with bitemporal hemianopsia and visual impairment accompanied by mildly elevated prolactin. Pathologic and molecular examination of the tissue removed transsphenoidally revealed 2 distinct tumors: pituitary adenoma and pituicytoma. To the best of our knowledge, histologically proven pituicytoma and pituitary adenoma have never been reported together.
authors.affiliation: Department of Neurosurgery, University Hospital Zurich, CH-8091 Zurich, Switzerland.
authors.forename: Marian C
authors.initials: MC
authors.lastname: Neidert
authors.affiliation: Department of Neuropathology, University Hospital Zurich, CH-8091 Zurich, Switzerland.
authors.forename: Henning
authors.initials: H
authors.lastname: Leske
authors.affiliation: Department of Neurosurgery, University Hospital Zurich, CH-8091 Zurich, Switzerland.
authors.forename: Jan-Karl
authors.initials: JK
authors.lastname: Burkhardt
authors.affiliation: Department of Neuroradiology, University Hospital Zurich, CH-8091 Zurich, Switzerland.
authors.forename: Spyros S
authors.initials: SS
authors.lastname: Kollias
authors.affiliation: Department of Neuropathology, University Hospital Heidelberg and German Cancer Consortium (DKTK), CCU Neuropathology, German Cancer Research Center (DKFZ), DE-69120 Heidelberg, Germany.
authors.forename: David
authors.initials: D
authors.lastname: Capper
authors.affiliation: Department of Neuropathology, University Hospital Heidelberg and German Cancer Consortium (DKTK), CCU Neuropathology, German Cancer Research Center (DKFZ), DE-69120 Heidelberg, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Schrimpf
authors.affiliation: Department of Neurosurgery, University Hospital Zurich, CH-8091 Zurich, Switzerland.
authors.forename: Luca
authors.initials: L
authors.lastname: Regli
authors.affiliation: Department of Neuropathology, University Hospital Zurich, CH-8091 Zurich, Switzerland. Electronic address: ElisabethJane.Rushing@usz.ch.
authors.forename: Elisabeth J
authors.initials: EJ
authors.lastname: Rushing
mesh_terms: D000236:Adenoma / Q000097:blood / Q000150:complications / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood / Q000235:genetics; D001706:Biopsy; D019175:DNA Methylation; D004724:Endoscopy; D005260:Female; D006423:Hemianopsia / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000097:blood / Q000150:complications / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D010911:Pituitary Neoplasms / Q000097:blood / Q000150:complications / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D011388:Prolactin / Q000097:blood; D014794:Visual Fields
chemical_list: D014408:Biomarkers, Tumor; D011388:Prolactin
keywords: MRI; Pituicyte; Pituicytoma; Pituitary adenoma; TTF1