title: Clinical Application of Superior Vena Cava Spectra in Evaluation of Pulmonary Hypertension: A Comparative Echocardiography and Catheterization Study.
abstract: This study was designed to assess whether superior vena cava (SVC) Doppler flow velocities are associated with invasive measures of pulmonary arterial pressure. Eighty patients with unrepaired congenital heart disease who underwent cardiac catheterization were included (31 men, 49 women; mean age: 37.3 ± 14.7 y). Compared with the non-pulmonary hypertension group, the moderate and severe pulmonary hypertension groups had decreased SVC ventricular reserve flow velocity and a significantly increased ratio of atrial reverse flow to systolic flow (AR/S). AR/S correlated significantly with invasive pulmonary arterial systolic pressure (r = 0.426, p < 0.0001). A cutoff of 0.45 had a sensitivity and specificity of 74% and 80%, respectively, for prediction of pulmonary hypertension. Good correlation also existed between SVC AR/S and pulmonary arterial systolic pressure in cases without tricuspid regurgitation (r = 0.706, p = 0.034). These results indicate that SVC AR/S may be an alternative method for assessing pulmonary hypertension.
authors.affiliation: Department of Ultrasound Diagnosis, Tangdu Hospital of the Fourth Military Medical University, Xi'an, Shaanxi, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Hou
authors.affiliation: Department of Ultrasound Diagnosis, Tangdu Hospital of the Fourth Military Medical University, Xi'an, Shaanxi, China; Department of Stomatology and Medical Imaging, Jilin Medical College, Jilin, Jilin, China.
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Sun
authors.affiliation: Department of Ultrasound Diagnosis, Tangdu Hospital of the Fourth Military Medical University, Xi'an, Shaanxi, China.
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Yuan
authors.affiliation: Department of Congenital Heart Disease Internal, General Hospital of Shenyang Military Area Command, Shenhe District, Shenyang, China.
authors.forename: Xian-Yang
authors.initials: XY
authors.lastname: Zhu
authors.affiliation: Department of Cardiology, Tangdu Hospital of the Fourth Military Medical University, Xi'an, Shaanxi, China.
authors.forename: Fu-Jun
authors.initials: FJ
authors.lastname: Shang
authors.affiliation: Department of Congenital Heart Disease Internal, General Hospital of Shenyang Military Area Command, Shenhe District, Shenyang, China.
authors.forename: Chuan-Ju
authors.initials: CJ
authors.lastname: Hou
authors.affiliation: Department of Ultrasound Diagnosis, Tangdu Hospital of the Fourth Military Medical University, Xi'an, Shaanxi, China. Electronic address: duanyy@fmmu.edu.cn.
authors.forename: Yun-You
authors.initials: YY
authors.lastname: Duan
mesh_terms: D000328:Adult; D062186:Arterial Pressure / Q000502:physiology; D001783:Blood Flow Velocity / Q000502:physiology; D006328:Cardiac Catheterization; D015150:Echocardiography, Doppler; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D012680:Sensitivity and Specificity; D014683:Vena Cava, Superior / Q000000981:diagnostic imaging* / Q000503:physiopathology*
keywords: Doppler; Pulmonary arterial pressure; Right heart catheterization; Superior vena cava