title: Late relapse of testicular cancer: Recurrence after 24 years and treatment with chemotherapy alone.
abstract: Late relapse of testicular cancer, defined as >2 years interval between initial treatment and recurrence, is a rare disease with the incidence rate of 2.6%. Due to its chemoresistant features, treatment options of late relapses are controversial while surgical approach and cisplatin-based chemotherapies can be considered. We report here a patient with nonseminomatous germ cell tumor who experienced relapse 24 years after his first diagnosis. After detecting left supraclavicular lymphadenopathy and absence of any other malignant lesion in positron emission tomography-computerized tomography, patient was treated with three cycles of VeIP regimen (vinblastine/ifosfamide/cisplatin). Second complete response to this treatment was achieved with chemotherapy alone.
authors.affiliation: Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Akar
authors.forename: Deniz
authors.initials: D
authors.lastname: Tural
authors.forename: Deniz
authors.initials: D
authors.lastname: Arslan
authors.forename: Cumhur İbrahim
authors.initials: Cİ
authors.lastname: Başsorgun
authors.forename: Özcan
authors.initials: Ö
authors.lastname: Yıldız
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D005047:Etoposide / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000517:prevention & control; D009373:Neoplasms, Germ Cell and Embryonal / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D011877:Radionuclide Imaging; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology
chemical_list: D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin