title: Laparoscopic total pelvic exenteration for pelvic malignancies: the technique and short-time outcome of 11 cases.
abstract: BACKGROUND
  Previous reports about laparoscopic total pelvic exenteration (LTPE) are still limited. In the present study, we described our single-center experience of the initial 11 cases.
  
  
  METHODS
  Between April 2011 and September 2015, eight males and three females diagnosed as pelvic malignancies underwent LTPE by the same operation team. We retrospectively collected all cases' parameters about surgical technique. Thirty-seven patients who received open surgery were also retrospectively collected. A comparison between LTPE and open surgery was performed to evaluate the feasibility and safety of LTPE.
  
  
  RESULTS
  Eleven cases successfully underwent the LTPE without any intraoperative complication. No open conversion was required. Eight patients underwent Bricker's procedure. Three patients were performed with the cutaneous ureterostomy. Anus preservation operation was performed in three patients. Compared with open surgery, LTPE had longer mean operative time (565.2 vs 468.2 min, p = 0.004) but less mean blood loss (547.3 vs 1033.0 ml, p < 0.001) and shorter postoperative hospitalization time (15.3 vs 22.4 days, p = 0.004). One patient died of pulmonary embolism in the 7th month of follow-up time. One patient died of recurrence in the 12th month of follow-up time. Nine patients are still alive without recurrence and metastasis. The mean follow-up time was 11.1 months.
  
  
  CONCLUSIONS
  The technique of LTPE seems to be feasible and safe in the treatment of carefully selected patients of pelvic malignancies. LTPE can also decrease the blood loss, the recovery time, and the hospital stay. But the oncological safety and long-term outcome of LTPE still need to be explored.
authors.affiliation: Department of Urology, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. yangkunlin12345@163.com.|Institute of Urology, Peking University, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. yangkunlin12345@163.com.|National Urological Cancer Center, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. yangkunlin12345@163.com.
authors.forename: Kunlin
authors.initials: K
authors.lastname: Yang
authors.affiliation: Department of Urology, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. drcailin@163.com.|Institute of Urology, Peking University, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. drcailin@163.com.|National Urological Cancer Center, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. drcailin@163.com.
authors.forename: Lin
authors.initials: L
authors.lastname: Cai
authors.affiliation: Department of Urology, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. poparies@163.com.|Institute of Urology, Peking University, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. poparies@163.com.|National Urological Cancer Center, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. poparies@163.com.
authors.forename: Lin
authors.initials: L
authors.lastname: Yao
authors.affiliation: Department of Urology, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. doczhz@aliyun.com.|Institute of Urology, Peking University, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. doczhz@aliyun.com.|National Urological Cancer Center, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. doczhz@aliyun.com.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Urology, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. 13641325575@126.com.|Institute of Urology, Peking University, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. 13641325575@126.com.|National Urological Cancer Center, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. 13641325575@126.com.
authors.forename: Cuijian
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Department of General Surgery, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. wangxin_guo@hotmail.com.|Institute of General Surgery, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. wangxin_guo@hotmail.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of General Surgery, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. doc_tjq@hotmail.com.|Institute of General Surgery, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. doc_tjq@hotmail.com.
authors.forename: Jianqiang
authors.initials: J
authors.lastname: Tang
authors.affiliation: Department of Urology, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. pineneedle@sina.com.|Institute of Urology, Peking University, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. pineneedle@sina.com.|National Urological Cancer Center, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. pineneedle@sina.com.
authors.forename: Xuesong
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Urology, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. wyj7074@sohu.com.|Institute of Urology, Peking University, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. wyj7074@sohu.com.|National Urological Cancer Center, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. wyj7074@sohu.com.
authors.forename: Zhisong
authors.initials: Z
authors.lastname: He
authors.affiliation: Department of Urology, Peking University First Hospital, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. zhoulqmail@china.com.|Institute of Urology, Peking University, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. zhoulqmail@china.com.|National Urological Cancer Center, No. 8 Xishiku St, Xicheng District, Beijing, 100034, China. zhoulqmail@china.com.
authors.forename: Liqun
authors.initials: L
authors.lastname: Zhou
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010385:Pelvic Exenteration; D010386:Pelvic Neoplasms / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D012371:Robotics