title: A structural snapshot of the rhodopsin-arrestin complex.
abstract: The crystal structure of the rhodopsin-arrestin complex provides important insights into how G protein-coupled receptor signaling is terminated by arrestin and a structural basis for understanding the mechanism of arrestin-based signaling.
authors.affiliation: Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA.
authors.forename: Yanyong
authors.initials: Y
authors.lastname: Kang
authors.affiliation: Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA.
authors.forename: Xiang
authors.initials: X
authors.lastname: Gao
authors.affiliation: Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA.|VARI-SIMM Center, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
authors.forename: X Edward
authors.initials: XE
authors.lastname: Zhou
authors.affiliation: Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA.
authors.forename: Yuanzheng
authors.initials: Y
authors.lastname: He
authors.affiliation: Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA.|VARI-SIMM Center, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
authors.forename: Karsten
authors.initials: K
authors.lastname: Melcher
authors.affiliation: Laboratory of Structural Sciences and Laboratory of Structural Biology and Biochemistry, Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA.|VARI-SIMM Center, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
authors.forename: H Eric
authors.initials: HE
authors.lastname: Xu
mesh_terms: D019390:Arrestins / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D006801:Humans; D008024:Ligands; D008051:Lipid Bilayers / Q000737:chemistry; D010766:Phosphorylation; D011485:Protein Binding; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D018343:Receptors, Adrenergic, beta-2 / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism*; D012243:Rhodopsin / Q000737:chemistry*; D015398:Signal Transduction
chemical_list: D019390:Arrestins; D008024:Ligands; D008051:Lipid Bilayers; D018343:Receptors, Adrenergic, beta-2; D043562:Receptors, G-Protein-Coupled; D012243:Rhodopsin
keywords: G protein; G protein-coupled receptors; Rhodopsin; arrestin; biased signalling