title: Successful treatment with carboplatin and pemetrexed for multiple lymph node metastases of lymphoepithelioma-like carcinoma from an unknown primary site.
abstract: We herein report the case of an 80-year-old Japanese man with multiple lymph node metastases of lymphoepithelioma-like carcinoma (LELC) from an unknown primary site. The patient was admitted to our hospital due to hoarseness and left supraclavicular lymphadenopathy. Contrast-enhanced whole-body computed tomography revealed mediastinal, left supraclavicular, and left axillary lymphadenopathy. A left supraclavicular lymph node biopsy was performed and the specimen was consequently diagnosed as exhibting LELC. The patient's Eastern Cooperative Oncology Group performance status was 0, therefore he was started on chemotherapy with carboplatin and pemetrexed. His lymph nodes responded well to four cycles of chemotherapy without any intolerable adverse effect.
authors.affiliation: Department of Respiratory Medicine, Iizuka Hospital, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Yasuda
authors.forename: Kazunori
authors.initials: K
authors.lastname: Tobino
authors.forename: Yuki
authors.initials: Y
authors.lastname: Ko
authors.forename: Mina
authors.initials: M
authors.lastname: Asaji
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Yamaji
authors.forename: Kosuke
authors.initials: K
authors.lastname: Tsuruno
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Miyajima
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Mukasa
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Ebi
mesh_terms: D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001706:Biopsy; D016190:Carboplatin / Q000627:therapeutic use*; D006801:Humans; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000188:drug therapy*; D008297:Male; D000068437:Pemetrexed / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D000068437:Pemetrexed; D016190:Carboplatin