title: [A girl with bilateral periorbital edema].
abstract: An 11-year-old girl was seen with painless, bilateral periorbital edema, that had appeared a week before presentation. Additional symptoms included fever, headache and malaise. Serological tests performed three days later showed an active Epstein-Barr virus infection, which provided the diagnosis 'Pfeiffer's disease'. Bilateral periorbital edema can be the presenting manifestation of Epstein-Barr virus infection and should therefore be included in its differential diagnosis.
authors.affiliation: Zuyderland Medisch Centrum, afd. Kindergeneeskunde, Sittard.
authors.forename: Mark R
authors.initials: MR
authors.lastname: Garrelfs
authors.forename: Jeroen R M
authors.initials: JR
authors.lastname: Romeijn
authors.forename: Jan W C M
authors.initials: JW
authors.lastname: Heynens
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D004487:Edema / Q000175:diagnosis / Q000209:etiology; D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005334:Fever / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D009916:Orbital Diseases / Q000175:diagnosis* / Q000209:etiology