title: [An ultrafast liquid chromatography-tandem mass spectrometric method for simultaneous determination of common artificial synthetic pigments in cooked meat products].
abstract: OBJECTIVE
  A method based on ultrafast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) has been developed for the simultaneous determination of seven synthetic pigments in cooked meat product.
  
  
  METHODS
  After the cooked meat products were extracted by mixed extraction agent, purified by WAX column, the UFLC separation was performed on a Shim-pack XR-ODS II column (75 mm x 2.0 mm, 2.2 µm) with a linear gradient elution program of acetonitrile and ammonium acetate (AmAc, 5 mmol/L) as the mobile phase. Electrospray ionization was applied and operated in the negative ion mode.
  
  
  RESULTS
  The limits of quantitation (LOQs) for the seven synthetic pigments were in the range of 0.7-5.0 µg/kg. The calibration curves showed good linearities for the seven analytes in their detection ranges, and the correlative coefficients (r) were more than 0.999. The recoveries were between 88.2%-106.5% with the RSDs in the range of 1.2%-5.0%.
  
  
  CONCLUSIONS
  The method is sensitive, reproducible, quick and adapts to the simultaneous determination of the seven synthetic pigments in cooked meat product.
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Chen
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Li
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Shengdong
authors.initials: S
authors.lastname: Pan
authors.forename: Micong
authors.initials: M
authors.lastname: Jin
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D008461:Meat Products / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*