title: Preparation of β-cyclodextrin entrapped graphite composite for sensitive detection of dopamine.
abstract: A simple dopamine (DA) electrochemical sensor was developed based on a screen-printed carbon electrode (SPCE) modified with β-cyclodextrin entrapped graphite (GR/β-CD) composite for the first time. The polar hydroxyl groups on the β-CD rims interact with polar groups of edges of GR sheets resulting into the high dispersion ability of GR in β-CD solution. The GR/β-CD modified electrode exhibited a higher electrochemical response to DA with a lower oxidation potential (0.224V) than that of bare/β-CD (0.38V) and GR (0.525V) modified SPCEs, revealing an excellent electro-oxidation behavior of GR/β-CD composite toward DA. Under optimum conditions, the fabricated sensor detects the DA in the linear concentration range from 0.1 to 58.5μM with a limit of detection of 0.011μM and the sensitivity of 1.27±0.02μAμM(-1)cm(-2). The fabricated sensor also exhibits the excellent repeatability, practicality, reproducibility, storage stability along with acceptable selectivity.
authors.affiliation: Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC.
authors.forename: Selvakumar
authors.initials: S
authors.lastname: Palanisamy
authors.affiliation: Chemistry Division, Center for General Education, Chang Gung University, No. 259, Wen-Hua 1st Rd., Gui-Shan, Tao-Yuan 33302, Taiwan, ROC.
authors.forename: S
authors.initials: S
authors.lastname: Sakthinathan
authors.affiliation: Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC. Electronic address: smchen78@ms15.hinet.net.
authors.forename: Shen-Ming
authors.initials: SM
authors.lastname: Chen
authors.affiliation: Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC.
authors.forename: Balamurugan
authors.initials: B
authors.lastname: Thirumalraj
authors.affiliation: Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan, ROC.
authors.forename: Tsung-Han
authors.initials: TH
authors.lastname: Wu
authors.affiliation: Chemistry Division, Center for General Education, Chang Gung University, No. 259, Wen-Hua 1st Rd., Gui-Shan, Tao-Yuan 33302, Taiwan, ROC. Electronic address: blou@mail.cgu.edu.tw.
authors.forename: Bih-Show
authors.initials: BS
authors.lastname: Lou
authors.affiliation: Key Laboratory of Education Ministry for Soft Chemistry and Functional Materials, Nanjing University of Science and Technology, Nanjing 210094, China. Electronic address: xhliu@mail.njust.edu.cn.
authors.forename: Xiaoheng
authors.initials: X
authors.lastname: Liu
mesh_terms: D004298:Dopamine / Q000032:analysis* / Q000737:chemistry; D055664:Electrochemical Techniques; D006108:Graphite / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D047392:beta-Cyclodextrins; D006108:Graphite; C031215:betadex; D004298:Dopamine
keywords: Differential pulse voltammetry; Dopamine; Graphite; Screen-printed carbon electrode; β-Cyclodextrin