title: Ovarian serous borderline tumors with noninvasive and invasive peritoneal implants: A case report each.
abstract: Serous borderline tumors (SBT) are defined by the World Health Organization (WHO) as serous neoplasms that show epithelial proliferation greater than that seen in serous cystadenomas, as evidenced by cellular stratification, cytologic atypicality, and epithelial tufting, but which exhibit no evidence of "destructive stromal" invasion and can show extra-ovarian implants. Characterization of invasive peritoneal implants from patients with noninvasive serous ovarian tumors has important prognostic and treatment implications. Peritoneal implants have been classified as either noninvasive or invasive based on their histopathologic appearance. Three criteria were applied for the diagnosis of "invasive" implants: Invasion of underlying normal tissue, micropapillary architecture, and solid epithelial nests surrounded by clefts. We encountered two cases of unilateral ovarian serous borderline tumors with non-invasive peritoneal implants in a 43-year-old female, and invasive peritoneal implants in 76-year-old female.
authors.affiliation: Department of Pathology, Sri Manakula Vinayagar Medical College, Puducherry, Tamil Nadu, India.
authors.forename: Banushree C
authors.initials: BC
authors.lastname: Srinivasamurthy
authors.forename: Ambedkar Raj
authors.initials: AR
authors.lastname: Kulandai Velu
authors.forename: Nagarajan
authors.initials: N
authors.lastname: Krishnan
authors.forename: Anand Shankar Rao
authors.initials: AS
authors.lastname: Patil
mesh_terms: D000328:Adult; D000368:Aged; D018283:Cystadenocarcinoma, Papillary / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery; D018284:Cystadenocarcinoma, Serous / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010053:Ovary / Q000473:pathology / Q000601:surgery; D010534:Peritoneal Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery