title: Health-related quality of life of Chinese patients with prostate cancer in comparison to general population and other cancer populations.
abstract: OBJECTIVE
  The purpose of this study was to compare the health-related quality of life (HRQOL) of Chinese patients with prostate cancer against the general population and patients with colorectal cancer, breast cancer, nasopharyngeal cancer, and leukemia.
  
  
  METHODS
  Chinese male patients (n = 291) with a confirmed diagnosis of prostate cancer were recruited from a urological specialist outpatient clinic in Hong Kong. HRQOL was measured by a condition-specific Functional Assessment of Cancer Therapy-Prostate (FACT-P) and a generic Chinese (HK) SF-12 Health Survey Version 2 (SF-12v2) questionnaire. Mean HRQOL scores of condition-specific and generic questionnaires were compared to available scores derived from other cancers and age-matched male general population, respectively.
  
  
  RESULTS
  Chinese patients with prostate cancer had lower general health and vitality domains and lower mental component summary scores than the age-matched Hong Kong normative population. Patients with prostate cancer reported better condition-specific HRQOL (physical well-being, emotional well-being and function well-being) when compared to general cancer population, patients with breast cancer, colorectal cancer, nasopharyngeal cancer, and leukemia in Hong Kong.
  
  
  CONCLUSIONS
  Patients with prostate cancer substantially perceived their HRQOL to be better, compared to patients with other cancers, with overall health, energy, and mental health below of Hong Kong general population. Interventions should target at these domains in order to improve the HRQOL of patients with prostate cancer. It is reassuring to find that prostate cancer had less negative impact on HRQOL than other cancer types did.
authors.affiliation: School of Nursing, The University of Hong Kong, 4/F, William M.W. Mong Block, 21 Sassoon Road, Pokfulam, Hong Kong. h0714919@connect.hku.hk.
authors.forename: Edmond P H
authors.initials: EP
authors.lastname: Choi
authors.affiliation: Department of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong Kong.
authors.forename: Carlos K H
authors.initials: CK
authors.lastname: Wong
authors.affiliation: Division of Urology, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong.
authors.forename: James H L
authors.initials: JH
authors.lastname: Tsu
authors.affiliation: Department of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong Kong.
authors.forename: W Y
authors.initials: WY
authors.lastname: Chin
authors.affiliation: Department of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong Kong.
authors.forename: Kenny
authors.initials: K
authors.lastname: Kung
authors.affiliation: Division of Urology, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong.
authors.forename: Charles K W
authors.initials: CK
authors.lastname: Wong
authors.affiliation: Division of Urology, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong.
authors.forename: M K
authors.initials: MK
authors.lastname: Yiu
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D018802:Patient-Centered Care / Q000379:methods*; D011471:Prostatic Neoplasms / Q000523:psychology*; D011788:Quality of Life; D011795:Surveys and Questionnaires
keywords: Chinese; Patient-reported outcome; Prostate cancer; Quality of life; Urology