title: Volumetric analysis of the diagonal band of Broca in patients with schizophrenia and affective disorders: A post-mortem study.
abstract: The human diagonal band of Broca is connected to other parts of the limbic system, such as the hippocampus, that are involved in the pathology of schizophrenia. This study aimed to characterize the volume and anterior-to-posterior distance of the human diagonal band of Broca (vertical limb) from post-mortem brains obtained from three groups: healthy control subjects (N = 17), patients with schizophrenia (N = 26), and patients with affective disorders (N = 12). There were no significant differences in the volume or anterior-to-posterior distance in the patients with schizophrenia or affective disorders compared with the healthy control subjects. To date, this is the first post-mortem investigation measuring the volume and the anterior-to-posterior distance of the diagonal band of Broca (vertical limb) in patients with schizophrenia or affective disorders compared with healthy control subjects.
authors.affiliation: Department of Forensic Medicine, Ul. Dębowa 23, Medical University of Gdańsk, Gdańsk, Poland.
authors.forename: Ralf
authors.initials: R
authors.lastname: Brisch
authors.affiliation: Department of Psychiatry and Psychotherapy, Otto-von-Guericke-University of Magdeburg, Magdeburg, Germany.
authors.forename: Hans-Gert
authors.initials: HG
authors.lastname: Bernstein
authors.affiliation: Department of Psychiatry and Psychotherapy, Otto-von-Guericke-University of Magdeburg, Magdeburg, Germany.
authors.forename: Henrik
authors.initials: H
authors.lastname: Dobrowolny
authors.affiliation: Department of Forensic Medicine, Ul. Dębowa 23, Medical University of Gdańsk, Gdańsk, Poland.
authors.forename: Marta
authors.initials: M
authors.lastname: Krzyżanowska
authors.affiliation: Department of Forensic Medicine, Ul. Dębowa 23, Medical University of Gdańsk, Gdańsk, Poland.
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Jankowski
authors.affiliation: Department of Psychiatry and Psychotherapy, Otto-von-Guericke-University of Magdeburg, Magdeburg, Germany.|Center for Behavioral Brain Sciences, Magdeburg, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Bogerts
authors.affiliation: Department of Forensic Medicine, Ul. Dębowa 23, Medical University of Gdańsk, Gdańsk, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Gos
mesh_terms: D016022:Case-Control Studies; D020667:Diagonal Band of Broca / Q000033:anatomy & histology* / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D019964:Mood Disorders / Q000473:pathology*; D012559:Schizophrenia / Q000473:pathology*; D020665:Septum of Brain / Q000033:anatomy & histology / Q000473:pathology
keywords: affective disorders; diagonal band of Broca; post-mortem brains; schizophrenia; volumetry