title: Candidemia from an upper urinary tract infection complicated by candida endophthalmitis.
abstract: A 51-year-old Japanese woman developed candidemia as an outpatient secondary to a Candida albicans upper urinary tract infection complicated by previously undiagnosed type 2 diabetes mellitus with poor glycemic control and ureterolithiasis. The patient did not have any risk factors typically associated with candidemia, such as an indwelling vascular catheter, parenteral nutrition or broad-spectrum antibiotic use. During the clinical course, her condition was complicated by unilateral candida endophthalmitis, which progressed despite the administration of systemic antifungal agents and ultimately required vitreous surgery. The etiology of candidemia in this patient and the reason she developed progressive ocular symptoms after starting antifungal treatment are reviewed.
authors.affiliation: Division of General Medicine, Department of Comprehensive Medicine 1, Saitama Medical Center, Jichi Medical University, Japan.
authors.forename: Reina
authors.initials: R
authors.lastname: Suzuki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kuroda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsubayashi
authors.forename: Akira
authors.initials: A
authors.lastname: Ishii
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Toyoda
authors.forename: Alan
authors.initials: A
authors.lastname: Kawarai Lefor
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Sugawara
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001786:Blood Glucose; D002176:Candida albicans; D058387:Candidemia / Q000188:drug therapy / Q000209:etiology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D009877:Endophthalmitis / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010289:Parenteral Nutrition, Total; D012307:Risk Factors; D053039:Ureterolithiasis / Q000150:complications; D014552:Urinary Tract Infections / Q000150:complications* / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D001786:Blood Glucose