title: Red-fleshed sweet orange juice improves the risk factors for metabolic syndrome.
abstract: Orange juice consumption can promote lower levels of oxidative stress and inflammation due to the antioxidant activity of citrus flavonoids and carotenoids. In addition, red-fleshed sweet orange juice (red orange juice) also contains lycopene. This study investigated the effects of red orange juice consumption on risk factors for metabolic syndrome. Volunteers consumed red orange juice daily for 8 weeks, with clinical and biochemical assessments performed at baseline and on the final day. There was no change in the abdominal obesity, but low-density lipoprotein cholesterol, C-reactive protein decreased, while there was an increase of the antioxidant activity in serum after red orange juice consumption. Insulin resistance and systolic blood pressure were reduced in normal-weight volunteers, while diastolic blood pressure decreased in overweight volunteers after intervention. Red orange juice showed anti-inflammatory, antioxidant, and lipid-lowering properties that may prevent the development of metabolic syndrome.
authors.affiliation: a Department of Food and Nutrition , Laboratory of Nutrition, School of Pharmaceutical Sciences, Univ Estadual Paulista - UNESP , Araraquara , SP , Brazil.
authors.forename: Jacqueline Q
authors.initials: JQ
authors.lastname: Silveira
authors.affiliation: a Department of Food and Nutrition , Laboratory of Nutrition, School of Pharmaceutical Sciences, Univ Estadual Paulista - UNESP , Araraquara , SP , Brazil.
authors.forename: Grace K Z S
authors.initials: GK
authors.lastname: Dourado
authors.affiliation: a Department of Food and Nutrition , Laboratory of Nutrition, School of Pharmaceutical Sciences, Univ Estadual Paulista - UNESP , Araraquara , SP , Brazil.
authors.forename: Thais B
authors.initials: TB
authors.lastname: Cesar
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use; D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D001794:Blood Pressure; D002097:C-Reactive Protein / Q000378:metabolism; D002338:Carotenoids / Q000494:pharmacology / Q000627:therapeutic use; D008078:Cholesterol, LDL / Q000097:blood; D032084:Citrus sinensis / Q000737:chemistry*; D004032:Diet; D005247:Feeding Behavior; D005260:Female; D005419:Flavonoids / Q000494:pharmacology / Q000627:therapeutic use; D000067030:Fruit and Vegetable Juices; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology / Q000627:therapeutic use; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D008875:Middle Aged; D050177:Overweight / Q000097:blood / Q000150:complications; D018384:Oxidative Stress / Q000187:drug effects; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D012307:Risk Factors
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D008078:Cholesterol, LDL; D005419:Flavonoids; D000960:Hypolipidemic Agents; D010936:Plant Extracts; D002338:Carotenoids; D002097:C-Reactive Protein
keywords: Abdominal obesity; citrus flavonoids; flavanones; insulin resistance; oxidative stress; red orange juice