title: Transurethral Resection of the Bladder Tumour as a Treatment Method in Children with Transitional Cell Carcinoma of the Bladder--Analysis of Our Material and Literature Review.
abstract: BACKGROUND
  Bladder cancer occurs mainly in adults. In children, younger than 10 years in particular, it is very rare.
  
  
  OBJECTIVE
  The aim of the study is to retrospectively evaluate the efficacy of transurethral resection of the bladder tumour (TUR-BT) of transitional cell carcinoma (TCC) of the bladder in children.
  
  
  METHODS
  Transurethral resection of the bladder tumour was performed in 7 boys aged 4 to 17 years (median 12.1 years). In all cases laboratory tests, ultrasound, and cystoscopic tumour biopsy were carried out prior to the resection. Doxorubicin was additionally instilled intravesically as one dose in two patients. The Foley catheter was left in the bladder for 1 to 4 days (median 1.85 days). The follow-up period ranged from 10 months to 10 years (median 4 years).
  
  
  RESULTS
  Papillary urothelial neoplasm of low malignant potential (PUNLMP) was diagnosed in 5 patients and urothelial papilloma in 2. Local recurrence was observed in one case two years after the resection. In all other cases complete remission was achieved.
  
  
  CONCLUSIONS
  Transitional cell carcinoma of the bladder in children is usually benign and endoscopic treatment (TUR-BT) seems to be the treatment of choice. To determine a follow-up schedule a more substantial group of children with bladder cancer should be analysed.
authors.affiliation: Department of Paediatric Surgery and Urology, Wroclaw Medical University, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Apoznański
authors.affiliation: Department of Paediatric Surgery and Urology, Wroclaw Medical University, Poland.
authors.forename: Jolanta
authors.initials: J
authors.lastname: Rysiakiewicz
authors.affiliation: Department of Paediatric Surgery and Urology, Wroclaw Medical University, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Polok
authors.affiliation: Department of Paediatric Surgery and Urology, Wroclaw Medical University, Poland.
authors.forename: Konrad
authors.initials: K
authors.lastname: Rysiakiewicz
authors.affiliation: Department of Paediatric Surgery and Urology, Wroclaw Medical University, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Siekanowicz
authors.affiliation: Department of Paediatric Surgery and Traumatology, Bieganski Regional Specialist Hospital, Grudziądz, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Hilger
authors.affiliation: Department of Paediatric Surgery and Traumatology, Bieganski Regional Specialist Hospital, Grudziądz, Poland.
authors.forename: Jan
authors.initials: J
authors.lastname: Zagierski
authors.affiliation: Department of Paediatry, Bieganski Regional Specialist Hospital, Grudziądz, Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Hilger
authors.affiliation: Department of Paediatry, Bieganski Regional Specialist Hospital, Grudziądz, Poland.
authors.forename: Irena
authors.initials: I
authors.lastname: Nowak
authors.affiliation: Department of Pathophysiology, Wroclaw Medical University, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Kolęda
authors.affiliation: Department of Palliative Care Nursing, Wroclaw Medical University, Poland; Department of Urology, 4th Military Clinical Hospital with Polyclinic, Wrocław, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Szydełko
mesh_terms: D000283:Administration, Intravesical; D000293:Adolescent; D000367:Age Factors; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D002295:Carcinoma, Transitional Cell / Q000473:pathology / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D002648:Child; D002675:Child, Preschool; D015653:Cystectomy / Q000009:adverse effects / Q000379:methods*; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D011044:Poland; D012074:Remission Induction; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000601:surgery*
chemical_list: D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin