title: Unique presentation of a plasmablastic lymphoma superficially involving the entire large bowel.
abstract: Plasmablastic lymphoma (PBL) is an uncommon, aggressive B-cell lymphoma mostly occurring in the oral cavity of human immunodeficiency virus (HIV) positive patients, but also described in extraoral sites and in HIV negative patients. One of the relatively common extraoral sites of PBL is the gastrointestinal (GI) tract. Few cases of PBL have been reported in association with inflammatory bowel disease (IBD). Here, we describe the unique presentation of a PBL involving the large bowel superficially along its entire length and without forming a tumor mass in an HIV negative patient with a recent diagnosis of ulcerative colitis.
authors.affiliation: Anatomic Pathology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors.forename: Magda
authors.initials: M
authors.lastname: Zanelli
authors.affiliation: Anatomic Pathology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy. Electronic address: moira.ragazzi@asmn.re.it.
authors.forename: Moira
authors.initials: M
authors.lastname: Ragazzi
authors.affiliation: Anatomic Pathology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Valli
authors.affiliation: Anatomic Pathology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors.forename: Loredana
authors.initials: L
authors.lastname: De Marco
authors.affiliation: Unit of Gastroenterology and Digestive Endoscopy, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Cecinato
authors.affiliation: Unit of Gastroenterology and Digestive Endoscopy, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Azzolini
authors.affiliation: Hematology Unit, IRCCS Santa Maria Nuova Hospital, Reggio Emilia, Italy.
authors.forename: Angela
authors.initials: A
authors.lastname: Ferrari
authors.affiliation: Hematopathology Section, Department of Experimental Diagnostic and Specialty Medicine, S.Orsola-Malpighi Hospital, Bologna University Medical School, Bologna, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Bacci
authors.affiliation: Institute of Pathology, Ospedale di Terni, University of Perugia, Perugia, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Ascani
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D059248:Chemoradiotherapy / Q000379:methods; D003093:Colitis, Ulcerative / Q000150:complications; D006801:Humans; D007414:Intestinal Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D007420:Intestine, Large / Q000473:pathology*; D008297:Male; D000069293:Plasmablastic Lymphoma / Q000150:complications / Q000473:pathology* / Q000628:therapy; D011878:Radiotherapy
keywords: Epstein–Barr virus; Immunosuppressive therapy; Inflammatory bowel disease; Plasmablastic lymphoma; Ulcerative colitis