title: Profile analysis of patients with HIV/AIDS hospitalized after the introduction of antiretroviral therapy.
abstract: Since the introduction of highly active antiretroviral therapy (HAART) in 1996, there have been worldwide shifts in the causes of hospitalization for patients with HIV/AIDS. The aim of this study was to describe the characteristics of HIV/AIDS patient hospitalizations between 1997 and 2012. This cross-sectional study used a hospital database that centralizes records of admissions in 31 hospitals, both public and private, across 26 municipalities in the interior of São Paulo. In order to verify associations between the variables, we used the prevalence ratio (PR) and a 95% confidence interval. Among 9,797 adults and children, 10,696 admissions were registered, which was equal to 1.09 admissions per patient. Most (62%) of the patients were male, and the predominant age group was 21 and 50 years (63.5%). Mortality was higher among male patients from all age groups (PR= 1.42 [95% CI: 1.28-1.57]; p < 0.05). The main cause of hospitalization (54.5% of the total) was infectious disease, whether opportunistic or not. This was true, even in the post-HAART era. Furthermore, gender and age differences were noted in patient mortality rates.
authors.affiliation: Departamento de Medicina Social, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil, altacilio@fmrp.usp.br.
authors.forename: Altacílio Aparecido
authors.initials: AA
authors.lastname: Nunes
authors.affiliation: Hospital das Clínicas, FMRP, Universidade de São Paulo, Brasil.
authors.forename: Laís Scalone
authors.initials: LS
authors.lastname: Caliani
authors.affiliation: Faculdade de Medicina de Itajubá, Brasil.
authors.forename: Maíra Souza
authors.initials: MS
authors.lastname: Nunes
authors.affiliation: Departamento de Medicina Social, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil, altacilio@fmrp.usp.br.
authors.forename: Anderson Soares
authors.initials: AS
authors.lastname: da Silva
authors.affiliation: Departamento de Medicina Social, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil, altacilio@fmrp.usp.br.
authors.forename: Luane Marques
authors.initials: LM
authors.lastname: de Mello
mesh_terms: D000163:Acquired Immunodeficiency Syndrome; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult