title: microRNAs calibrate T cell responses by regulating mTOR.
authors.affiliation: MRC Clinical Sciences Centre, Imperial College London, London, UK.
authors.forename: Matthias
authors.initials: M
authors.lastname: Merkenschlager
authors.affiliation: CIRI, International Center for Infectiology Research, Université de Lyon, Inserm, CNRS, Ecole Normale Supérieure, Lyon, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Marcais
mesh_terms: D053487:DEAD-box RNA Helicases / Q000235:genetics; D005786:Gene Expression Regulation / Q000276:immunology*; D006801:Humans; D008213:Lymphocyte Activation / Q000276:immunology*; D000076222:Mechanistic Target of Rapamycin Complex 1; D000076225:Mechanistic Target of Rapamycin Complex 2; D035683:MicroRNAs / Q000235:genetics* / Q000276:immunology; D046912:Multiprotein Complexes / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D043244:Ribonuclease III / Q000235:genetics; D013601:T-Lymphocytes / Q000276:immunology*; D058570:TOR Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism*
chemical_list: D035683:MicroRNAs; D046912:Multiprotein Complexes; D012333:RNA, Messenger; D011948:Receptors, Antigen, T-Cell; C546842:MTOR protein, human; D000076222:Mechanistic Target of Rapamycin Complex 1; D000076225:Mechanistic Target of Rapamycin Complex 2; D058570:TOR Serine-Threonine Kinases; C408087:DICER1 protein, human; D043244:Ribonuclease III; D053487:DEAD-box RNA Helicases
keywords: T cell activation; anergy; interleukin-2; mTOR; microRNA