title: [Comparison of the effectiveness of percutaneous microwave ablation versus hepatectomy for hepatocellular carcinoma].
abstract: OBJECTIVE
  To compare the effectiveness of percutaneous microwave ablation ( MWA) versus hepatectomy for multifocal hepatocellular carcinoma.
  
  
  METHODS
  From August 2002 to March 2012, one hundred and twenty-two patients with multifocal hepatocellular carcinoma (diameters 1 to 7 cm, 2 to 4 lesions) were treated by either complete MWA or radical hepatectomy, and their clinical data were collected and analyzed.The patients were divided into MWA group (n = 50) and resection group (n = 72), and the resection group was matched by MWA group based on clinical parameters. The survival and complications in the two groups were compared.
  
  
  RESULTS
  The overall 1-, 3- and 5-year survival rates were 100.0%, 73.0% and 62.0%, respectively, in the MWA group, and 80.0%, 56.0%, and 41.0%, respectively, in the resection group (P < 0.05). The corresponding recurrence-free survival rates were 88.0%, 63.0%, and 52.0% in the MWA group, and 68.0%, 45.0%, and 36.0%, respectively, in the resection group (P< 0.05). The multivariate Cox regression analysis indicated that albumin level, performance status, treatment modality, and tumor size were independent prognostic factors.
  
  
  CONCLUSIONS
  Compared with hepatectomy, percutaneous microwave ablation is a minimally invasive and reproducible procedure, and can improve the survival in patients with multifocal hepatocellular carcinoma.
authors.forename: Li
authors.initials: L
authors.lastname: Sheng
authors.forename: Yiqi
authors.initials: Y
authors.lastname: Wang
authors.forename: Dong
authors.initials: D
authors.lastname: Jun
authors.forename: Wu
authors.initials: W
authors.lastname: Peihong
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery*; D017115:Catheter Ablation; D005818:Genetic Engineering; D006498:Hepatectomy / Q000401:mortality; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery*; D008872:Microwaves / Q000627:therapeutic use*; D012044:Regression Analysis; D015996:Survival Rate; D016896:Treatment Outcome