title: The reason sickle reticulocytes expose PS.
abstract: In this issue of Blood, Mankelow et al link phosphatidylserine (PS) exposure in sickle erythrocytes to a physiological event in reticulocyte maturation. This discovery has implications for efforts to prevent thrombosis in sickle cell disease (SCD).
authors.affiliation: UNIVERSITY OF PENNSYLVANIA;
authors.forename: Dennis E
authors.initials: DE
authors.lastname: Discher
authors.affiliation: THE NEW YORK BLOOD CENTER.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Ney
mesh_terms: D000755:Anemia, Sickle Cell / Q000097:blood* / Q000473:pathology*; D001343:Autophagy; D004912:Erythrocytes / Q000473:pathology*; D006801:Humans; D010718:Phosphatidylserines / Q000378:metabolism*; D012156:Reticulocytes / Q000473:pathology*
chemical_list: D010718:Phosphatidylserines