title: Streptococcal M1 Strikes by Neutralizing Cathelicidins.
abstract: Virulent group A streptococci have become a serious threat, with the emergence of the hypervirulent lineage M1T1. In this issue of Cell Host & Microbe, LaRock et al. (2015), uncover a role for the streptococcal M1 protein in neutralizing a key human antimicrobial peptide, cathelicidin.
authors.affiliation: Department of Microbiology, Cell Biology and Tumorbiology, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Clinical Microbiology, Karolinska University Hospital, 171 76 Stockholm, Sweden. Electronic address: birgitta.henriques@ki.se.
authors.forename: Birgitta
authors.initials: B
authors.lastname: Henriques-Normark
authors.affiliation: Department of Microbiology, Cell Biology and Tumorbiology, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Clinical Microbiology, Karolinska University Hospital, 171 76 Stockholm, Sweden.
authors.forename: Staffan
authors.initials: S
authors.lastname: Normark
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000378:metabolism*; D023181:Antimicrobial Cationic Peptides / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D006801:Humans; D057131:Immune Evasion; D013297:Streptococcus pyogenes / Q000276:immunology* / Q000378:metabolism*
chemical_list: D000942:Antigens, Bacterial; D023181:Antimicrobial Cationic Peptides; D001425:Bacterial Outer Membrane Proteins; D002352:Carrier Proteins