title: A case report on 1-year follow-up of bilateral thalamic glioma.
abstract: Bilateral thalamic glioma is one of the rarest tumor occurrences, representing a small fraction of thalamic gliomas, which only accounts for 1-1.5% of all brain tumors. It is usually a diffuse, low-grade astrocytoma (WHO grade II), seen mainly in adults, with approximately 25% of them involving children under the age of 15. Radiotherapy is the main mode of treatment since surgical intervention is limited to a role of biopsy and management of secondary effects, due to the deep brain location of the lesion and the complexity of the involved structures. We report a 1-year follow-up of a 55-year-old female patient with bilateral WHO grade II thalamic astrocytoma. Following histological and neuroradiological consensus regarding the diagnosis, the patient was referred for radiotherapy. The effectiveness of available therapy and long-term neuroradiological follow-up is not reliably established due to rapid fatal evolution following diagnosis. Contrary to the norm, our patient showed stable disease with radiotherapy for a 1-year period.
authors.affiliation: Institute for Neuroradiology University Hospital of Zurich, Switzerland Royal Melbourne Hospital, Melbourne, Australia erangaganewatte@ymail.com.
authors.forename: Eranga
authors.initials: E
authors.lastname: Ganewatte
authors.affiliation: Institute for Neuroradiology University Hospital of Zurich, Switzerland.
authors.forename: Yahea
authors.initials: Y
authors.lastname: Al-Zahrani
authors.affiliation: Institute for Neuroradiology University Hospital of Zurich, Switzerland.
authors.forename: Bela
authors.initials: B
authors.lastname: Purohit
authors.affiliation: Institute for Neuroradiology University Hospital of Zurich, Switzerland.
authors.forename: Spyros
authors.initials: S
authors.lastname: Kollias
mesh_terms: D001254:Astrocytoma / Q000000981:diagnostic imaging / Q000473:pathology; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011877:Radionuclide Imaging; D013786:Thalamic Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D013787:Thalamic Nuclei / Q000000981:diagnostic imaging / Q000473:pathology; D013788:Thalamus / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Thalamic; bilateral; glioma