title: Major depression treatment in Germany-descriptive analysis of health insurance fund routine data and assessment of guideline-adherence.
abstract: BACKGROUND
  Guideline oriented treatment strategies of Major depressive disorder (MDD) improve treatment outcomes and reduce risks of chronicity and recurrence.
  
  
  OBJECTIVE
  Description of routine treatment reality and analysis of guideline fidelity in first episode MDD in Germany. Indicators: patients with severe or psychotic depression or severe psychiatric comorbidities' treatment by specialists, adequate antidepressant pharmacotherapy, permanent treatment with more than one antidepressant, long-term benzodiazepine treatment and provision of psychotherapy.
  
  
  METHODS
  Descriptive analysis of routine data of the German statutory health insurance fund Barmer GEK in the index year 2011 that covers a population of 7,501,110.
  
  
  RESULTS
  236,843 patients were diagnosed a depressive episode. 53.0% of the patients with severe depression, 34.4% with psychotic depression and 50.9% with severe psychiatric comorbidities were treated by specialists; of the patients treated by a general practitioner 48.1% with severe and 47.3% with psychotic depression received an antidepressant; 9.7% of all patients with MDD got two antidepressants simultaneously; 8.3% received longterm benzodiazepine prescriptions; 26.1% got psychotherapy.
  
  
  CONCLUSIONS
  the analyses depends on the indicators definitions that cannot cope with the variety of individual treatment path; comparison with guidelines was complicated by a large fraction of patients with recurrent MDD that was wrongly diagnosed with first episode depression; due to the data structure, not all guideline recommendations could be examined
  
  
  CONCLUSIONS
  Routine practice was oriented upon the guidelines recommendations. However some aspects could be identified that bear potential for improvements.
authors.affiliation: Department of Psychiatry, Psychotherapy and Psychosomatics, St. Joseph-Krankenhaus Berlin Weißensee, Gartenstr. 1-3, 13088 Berlin, Germany. Electronic address: hauke.wiegand@gmx.net.
authors.forename: Hauke Felix
authors.initials: HF
authors.lastname: Wiegand
authors.affiliation: BARMER GEK Hauptverwaltung Strategische Analysen/Risikomanagement, Lichtscheider Str. 89, 42285 Wuppertal, Germany. Electronic address: christoph.sievers@barmer-gek.de.
authors.forename: Christoph
authors.initials: C
authors.lastname: Sievers
authors.affiliation: St. Joseph-Krankenhaus Berlin Weißensee Gartenstr. 1-3, 13088 Berlin, Germany. Electronic address: m.schillinger@alexius.de.
authors.forename: Matthias
authors.initials: M
authors.lastname: Schillinger
authors.affiliation: Department of Psychiatry and Behavioural Medicine, St. Joseph-Krankenhaus Berlin Weißensee Gartenstr. 1-3, 13088 Berlin, Germany. Electronic address: f.godemann@alexius.de.
authors.forename: Frank
authors.initials: F
authors.lastname: Godemann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000928:Antidepressive Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D005858:Germany; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006801:Humans; D007348:Insurance, Health; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D011613:Psychotherapy; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000928:Antidepressive Agents
keywords: Antidepressants; Guideline adherence; Major depressive disorder; Psychotherapy; Public health