title: Roth Spots in Ocular Toxoplasmosis.
abstract: OBJECTIVE
  To report a case with unilateral preexisting ocular toxoplasmosis (OT) and newly occurred active retinochoroidal inflammation associated with white-centered retinal hemorrhages (Roth spots) in the healthy eye.
  
  
  METHODS
  Case report.
  
  
  METHODS
  A 20 year-old man presented with a decrease of visual acuity in his right eye associated with 2+ cells in the anterior chamber. Ophthalmoscopy revealed an active retinochoroidal lesion on the upper nasal border of the optic disc associated with local hemorrhage and vitritis. The posterior pole presented white-centered flame-shaped retinal hemorrhages.
  
  
  RESULTS
  Toxoplasmosis serology showed an IgG titer >300IU/ml and a negative IgM titer. A complete blood count revealed no abnormalities; other serologies were negative. After 2 weeks of treatment with sulfadiazine, pyrimethamine, folinic acid and prednisone, although the peripapillary lesion was still active, the Roth spots disappeared.
  
  
  CONCLUSIONS
  OT may be one differential diagnosis of patients suffering Roth spots in association with retinochoroidal inflammation.
authors.affiliation: a Departamento de Oftalmologia , Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo , São Paulo , Brazil.
authors.forename: João M
authors.initials: JM
authors.lastname: Furtado
authors.affiliation: a Departamento de Oftalmologia , Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo , São Paulo , Brazil.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Toscano
authors.affiliation: a Departamento de Oftalmologia , Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo , São Paulo , Brazil.
authors.forename: Vinicius
authors.initials: V
authors.lastname: Castro
authors.affiliation: a Departamento de Oftalmologia , Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo , São Paulo , Brazil.
authors.forename: Murilo W
authors.initials: MW
authors.lastname: Rodrigues
mesh_terms: D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002825:Chorioretinitis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D009887:Ophthalmoscopy; D011739:Pyrimethamine / Q000627:therapeutic use; D012166:Retinal Hemorrhage / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D013411:Sulfadiazine / Q000627:therapeutic use; D041623:Tomography, Optical Coherence; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D014786:Vision Disorders / Q000175:diagnosis; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D000981:Antiprotozoal Agents; D007074:Immunoglobulin G; D013411:Sulfadiazine; D011739:Pyrimethamine
keywords: Roth Spots; Toxoplasma gondii; Uveitis; intraocular infection; ocular toxoplasmosis