title: Implantable atrial flow regulator for severe, irreversible pulmonary arterial hypertension.
abstract: Pulmonary arterial hypertension (PAH) is a severe, progressive and fatal disease. The creation of an interatrial right-to-left shunt in patients with PAH may enhance systemic ventricular output at the expense of desaturation. However, creating sustainable restricted interatrial communication is challenging. We describe the successful use of an atrial flow regulator, a novel implantable atrial communication device, in a 54-year-old female with severe irreversible PAH.
authors.affiliation: Congenital Heart Center, Helen DeVos Children's Hospital of Spectrum Health, Grand Rapids, MI, USA.
authors.forename: Mehul B
authors.initials: MB
authors.lastname: Patel
authors.forename: Bennett P
authors.initials: BP
authors.lastname: Samuel
authors.forename: Reda E
authors.initials: RE
authors.lastname: Girgis
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Parlmer
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Vettukattil
mesh_terms: D016279:Atrial Function, Left; D016280:Atrial Function, Right; D006328:Cardiac Catheterization / Q000295:instrumentation*; D003326:Coronary Circulation; D018618:Echocardiography, Doppler, Color; D019560:Echocardiography, Three-Dimensional; D004630:Emergencies; D004867:Equipment Design; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D008875:Middle Aged; D012720:Severity of Illness Index; D016896:Treatment Outcome