title: Cobalt-Catalyzed Alkylation of Aromatic Amines by Alcohols.
abstract: The implementation of inexpensive, Earth-abundant metals in typical noble-metal-mediated chemistry is a major goal in homogeneous catalysis. A sustainable or green reaction that has received a lot of attention in recent years and is preferentially catalyzed by Ir or Ru complexes is the alkylation of amines by alcohols. It is based on the borrowing hydrogen or hydrogen autotransfer concept. Herein, we report on the Co-catalyzed alkylation of aromatic amines by alcohols. The reaction proceeds under mild conditions, and selectively generates monoalkylated amines. The observed selectivity allows the synthesis of unsymmetrically substituted diamines. A novel Co complex stabilized by a PN5 P ligand catalyzes the reactions most efficiently.
authors.affiliation: Anorganische Chemie II-Katalysatordesign, Universität Bayreuth, 95440 Bayreuth (Germany).
authors.forename: Sina
authors.initials: S
authors.lastname: Rösler
authors.affiliation: Anorganische Chemie II-Katalysatordesign, Universität Bayreuth, 95440 Bayreuth (Germany).
authors.forename: Michael
authors.initials: M
authors.lastname: Ertl
authors.affiliation: Anorganische Chemie II-Katalysatordesign, Universität Bayreuth, 95440 Bayreuth (Germany).
authors.forename: Torsten
authors.initials: T
authors.lastname: Irrgang
authors.affiliation: Anorganische Chemie II-Katalysatordesign, Universität Bayreuth, 95440 Bayreuth (Germany). kempe@uni-bayreuth.de.
authors.forename: Rhett
authors.initials: R
authors.lastname: Kempe
keywords: alcohols; amine alkylation; base metals; cobalt; hydrogen-transfer catalysis