title: Biological activity of Stevia rebaudiana Bertoni and their relationship to health.
abstract: The leaves of Stevia rebaudiana Bertoni has nutrients and phytochemicals, which make it an adequate source for the extraction and production of functional food ingredients. Preclinical and clinical studies suggest therapeutic and pharmacological applications for stevia and their extracts because they are not toxic and exhibit several biological activities. This review presents the biological activity of Stevia rebaudiana Bertoni and their relationship to antidiabetic, anticariogenic, antioxidant, hypotensive, antihypertensive, antimicrobial, anti-inflammatory and antitumor activities. Consumption and adverse effects were also reviewed.
authors.affiliation: a Departamento de Ingeniería Química-Bioquímica , Instituto Tecnológico de Mérida , Mérida, Yucatán , México.
authors.forename: Jorge Carlos
authors.initials: JC
authors.lastname: Ruiz-Ruiz
authors.affiliation: b Instituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias, Campo Experimental Mococh , Carretera Mérida-Motul, Yucatán , México.
authors.forename: Yolanda Beatriz
authors.initials: YB
authors.lastname: Moguel-Ordoñez
authors.affiliation: c Facultad de Ingeniería Química , Universidad Autónoma de Yucatán Col. Chuburná de Hidalgo Inn, Mérida, Yucatán , México.
authors.forename: Maira Rubi
authors.initials: MR
authors.lastname: Segura-Campos
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D045786:Diterpenes, Kaurane; D006801:Humans; D064209:Phytochemicals; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D036625:Stevia / Q000737:chemistry*; D013549:Sweetening Agents
chemical_list: D000975:Antioxidants; D045786:Diterpenes, Kaurane; D064209:Phytochemicals; D010936:Plant Extracts; D013549:Sweetening Agents
keywords: Stevia rebaudiana; bioactivity; extracts; steviol glycosides