title: Antibacterial Coatings: Challenges, Perspectives, and Opportunities.
abstract: Antibacterial coatings are rapidly emerging as a primary component of the global mitigation strategy of bacterial pathogens. Thanks to recent concurrent advances in materials science and biotechnology methodologies, and a growing understanding of environmental microbiology, an extensive variety of options are now available to design surfaces with antibacterial properties. However, progress towards a more widespread use in clinical settings crucially depends on addressing the key outstanding issues. We review release-based antibacterial coatings and focus on the challenges and opportunities presented by the latest generation of these materials. In particular, we highlight recent approaches aimed at controlling the release of antibacterial agents, imparting multi-functionality, and enhancing long-term stability.
authors.affiliation: Laboratory for Biomaterials and Bioengineering, Department of Min-Met-Materials Engineering, and Centre Hospitalier Universitaire de Québec Research Center, Laval University, Pavillon Pouliot, Local 1745-E, Québec, QC, G1V 0A6, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Cloutier
authors.affiliation: Laboratory for Biomaterials and Bioengineering, Department of Min-Met-Materials Engineering, and Centre Hospitalier Universitaire de Québec Research Center, Laval University, Pavillon Pouliot, Local 1745-E, Québec, QC, G1V 0A6, Canada. Electronic address: diego.mantovani@gmn.ulaval.ca.
authors.forename: D
authors.initials: D
authors.lastname: Mantovani
authors.affiliation: Institut National de la Recherche Scientifique (INRS), 1650 Boulevard Lionel Boulet, Varennes, QC, J3X 1S2 Canada; Institute for Fundamental and Frontier Science, University of Electronic Science and Technology of China, Chengdu 610054, PR China. Electronic address: rosei@emt.inrs.ca.
authors.forename: F
authors.initials: F
authors.lastname: Rosei
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004783:Environmental Microbiology; D012834:Silver / Q000494:pharmacology*; D013499:Surface Properties
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver
keywords: antibacterial agent release; antibacterial coatings; controlled release; multifunctional coatings; stability