title: On the role of HNS and HSN as light-sensitive NO-donors for delivery in biological media.
abstract: Results are presented that suggest that thiazyl hydride (HSN)/thionitrosyl hydride (sulfimide, HNS) can be used as light-sensitive compounds for NO-delivery in biological media, as well as markers for the possible detection of intermediates in nitrites + H2S reactions at the cellular level. They are expected to be more efficient than the HNO/HON isovalent species and hence they should be considered instead. A set of characteristic spectroscopic features are identified that could aid in the possible detection of these species in the gas phase or in biological environments. The possibility of intramolecular dynamical processes involving excited states that are capable of interconverting HNS and its isomeric form HSN is examined.
authors.affiliation: Laboratoire de Spectroscopie Atomique, Moléculaire et Applications-LSAMA, Université de Tunis El Manar, Tunis, Tunisia.
authors.forename: Tarek
authors.initials: T
authors.lastname: Trabelsi
authors.affiliation: Laboratoire Modélisation et Simulation Multi Echelle, MSME UMR 8208 CNRS, Université Paris-Est, 5 bd Descartes, 77454 Marne-la-Vallée, France.
authors.forename: Roberto
authors.initials: R
authors.lastname: Linguerri
authors.affiliation: Laboratoire de Spectroscopie Atomique, Moléculaire et Applications-LSAMA, Université de Tunis El Manar, Tunis, Tunisia.
authors.forename: Saida
authors.initials: S
authors.lastname: Ben Yaghlane
authors.affiliation: Laboratoire de Spectroscopie Atomique, Moléculaire et Applications-LSAMA, Université de Tunis El Manar, Tunis, Tunisia.
authors.forename: Nejm-Eddine
authors.initials: NE
authors.lastname: Jaidane
authors.affiliation: Chemistry Department, Faculty of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Kingdom of Saudi Arabia.
authors.forename: Muneerah
authors.initials: M
authors.lastname: Mogren Al-Mogren
authors.affiliation: Department of Chemistry and Department of Earth and Atmospheric Sciences, Purdue University, West Lafayette, Indiana 47906, USA.
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Francisco
authors.affiliation: Laboratoire Modélisation et Simulation Multi Echelle, MSME UMR 8208 CNRS, Université Paris-Est, 5 bd Descartes, 77454 Marne-la-Vallée, France.
authors.forename: Majdi
authors.initials: M
authors.lastname: Hochlaf
mesh_terms: D004583:Electrons; D008027:Light; D009569:Nitric Oxide / Q000737:chemistry*; D009589:Nitrogen Oxides / Q000737:chemistry*; D011789:Quantum Theory; D013844:Thiazoles / Q000737:chemistry*
chemical_list: D009589:Nitrogen Oxides; D013844:Thiazoles; D009569:Nitric Oxide; C087991:nitrosyl chloride