title: Malignant melanoma in organ transplant recipients: incidence, outcomes, and management strategies: a review of literature.
abstract: Malignant melanoma is considered to be an immunogenic tumor, which is expected to change its behaviour in the field of immunosuppression. Although the incidence of melanoma in organ transplant recipients is increased to a smaller degree than in non-melanoma skin cancer, its potential morbidity and mortality has to be considered in the posttransplant care. The aim of this review is to investigate the relationship between melanoma and immunosuppression and to discuss management strategies for different melanoma scenarios in pre-transplant as well as posttransplant period.
authors.affiliation: Department of Dermatology, 2nd Medical Faculty, Charles University in Prague and Bulovka Hospital, Prague, Czech Republic.
authors.forename: Martina
authors.initials: M
authors.lastname: Džambová
authors.affiliation: Department of Dermatology, 2nd Medical Faculty, Charles University in Prague and Bulovka Hospital, Prague, Czech Republic.
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Sečníková
authors.affiliation: Department of Dermatology, 2nd Medical Faculty, Charles University in Prague and Bulovka Hospital, Prague, Czech Republic.
authors.forename: Anna
authors.initials: A
authors.lastname: Jiráková
authors.affiliation: Department of Dermatology, 2nd Medical Faculty, Charles University in Prague and Bulovka Hospital, Prague, Czech Republic.
authors.forename: Kateřina
authors.initials: K
authors.lastname: Jůzlová
authors.affiliation: Department of Nephrology, Institute of Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Ondřej
authors.initials: O
authors.lastname: Viklický
authors.affiliation: Department of Cardiology, Institute of Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Lenka
authors.initials: L
authors.lastname: Hošková
authors.affiliation: Department of Epidemiology, 2nd Medical Faculty, Charles University in Prague, Prague, Czech Republic.
authors.forename: Dana
authors.initials: D
authors.lastname: Göpfertovà
authors.affiliation: Department of Dermatology, 2nd Medical Faculty, Charles University in Prague and Bulovka Hospital, Prague, Czech Republic.
authors.forename: Jana
authors.initials: J
authors.lastname: Hercogová
mesh_terms: D046148:Donor Selection; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D015994:Incidence; D008545:Melanoma / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy*; D016377:Organ Transplantation / Q000009:adverse effects*; D018570:Risk Assessment; D012307:Risk Factors; D012878:Skin Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy*; D013997:Time Factors; D014019:Tissue Donors; D066027:Transplant Recipients; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents
keywords: immunosuppression; malignant melanoma; prognosis; therapy