title: [The role of hematopoietic stem cell transplantation for acute myeloid leukemia].
abstract: Hematopoietic stem cell transplantation (HSCT) plays an important role in treating younger patients with acute myeloid leukemia (AML). Reduced-intensity conditioning regimens allow increased use of allogeneic HSCT for older patients. Current HSCT decisions in patients with AML are being made according to cytogenetic analysis results. A more comprehensive and detailed understanding of the genetic and epigenetic changes that are related to the pathogenesis of AML is required for better classification of risk and for improving approaches to therapy as they pertain to future HSCT decisions.
authors.affiliation: Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science.
authors.forename: Koji
authors.initials: K
authors.lastname: Kato
mesh_terms: D000367:Age Factors; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000628:therapy*; D017410:Practice Guidelines as Topic; D012008:Recurrence; D012307:Risk Factors; D016896:Treatment Outcome