title: It's "PT" for SCD!
abstract: In this issue of Blood, Arumugam et al report that long-term reduction of prothrombin (PT) expression results in diminished vascular inflammation, attenuation of multiple organ damage, and survival advantage in a mouse model of sickle cell disease (SCD).
authors.affiliation: UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL.
authors.forename: Rafal
authors.initials: R
authors.lastname: Pawlinski
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications*; D000818:Animals; D015316:Genetic Therapy; D006976:Hypertension, Pulmonary / Q000517:prevention & control*; D007249:Inflammation / Q000517:prevention & control*; D008297:Male; D011516:Prothrombin / Q000502:physiology*; D014652:Vascular Diseases / Q000517:prevention & control*
chemical_list: D011516:Prothrombin