title: Primary non-Hodgkin lymphoma of the vulva in an immunocompetent patient.
abstract: The primary non-Hodgkin lymphoma of the vulva is a very rare pathological entity. We report a case of 37-year-old patient that presented a germinating ulcerating tumor in the small right vulva. The histology objectified a B lymphoma with a positive CD20 reaction. The patient underwent three typical chemotherapy sessions by rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone, followed by external radiotherapy on the pelvis and bilateral inguinal lymph nodes areas with an excellent answer and survival without particular events within 36 months of recession. Through this case report, we discuss the diagnostic features of this pathological entity, considering diagnosis and treatment are different compared to other tumors that are commonly found in the vulva.
authors.affiliation: Department of Radiotherapy, National Institute of Oncology, Faculty of Medicine and Pharmacy of Rabat, Morocco.
authors.forename: Hanan
authors.initials: H
authors.lastname: El Kacemi
authors.forename: Issam
authors.initials: I
authors.lastname: Lalya
authors.forename: Tayeb
authors.initials: T
authors.lastname: Kebdani
authors.forename: Noureddine
authors.initials: N
authors.lastname: Benjaafar
mesh_terms: D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000378:metabolism; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000378:metabolism; D011859:Radiography; D014846:Vulvar Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000378:metabolism
chemical_list: D015703:Antigens, CD; D014408:Biomarkers, Tumor