title: [Renal damage caused by Rhupus syndrome associated with anti-neutrophil cytoplasmic antibodies vasculitis and cryoglobulinemia].
abstract: We analyzed the clinicopathological characteristics of one patient with Rhupus syndrome associated nephropathy in Peking University People's Hospital, and reviewed the related literature. The patient was a middle aged female. She developed rheumatoid arthritis first, and then manifested mild systemic lupus erythematosus together with positive anti-neutrophil cytoplasmic antibodies (ANCA) and cryoglobulinemia several years later. The renal biopsy was performed and manifested as lupus nephritis. The transmission electron microscopy revealed cryoglobulinemia associated renal damage. This report shows that the clinicopathological characteristics in patients with Rhupus syndrome associated nephropathy are complicated. The renal pathology can be used as a diagnostic tool.
authors.affiliation: Department of Nephrology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Xin-ju
authors.initials: XJ
authors.lastname: Zhao
authors.affiliation: Department of Nephrology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wei
authors.affiliation: Department of Nephrology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Bao
authors.initials: B
authors.lastname: Dong
authors.affiliation: Department of Rheumatology and Immunology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Jia
authors.affiliation: Department of Nephrology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Mei
authors.initials: M
authors.lastname: Wang
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic; D001172:Arthritis, Rheumatoid; D000068476:Beijing; D003449:Cryoglobulinemia / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008180:Lupus Erythematosus, Systemic; D008181:Lupus Nephritis; D008875:Middle Aged; D014657:Vasculitis
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic