title: Glomus tumor of the trachea: a rare case report.
abstract: A tracheal glomus tumor is extremely rare. There were approximately 18 reported cases before in China. Here we report a 48-year-old male with glomus tumor of the trachea. The computed tomography (CT) scan of the chest showed a nodulein the basalsegmentof right lower lobe, focal uplift in the left-posterior wall of the trachea, measured 1.5×1.2×1.0 cm. Microscopically, the tumor tissue was rich with vessels, shaped flake-nest, and the tumor consisted of a sheet of uniform cells surrounding the vascular spaces. Immumohistochemical staining were positive for SMA, vimentin, collagen IV, CD34, the Ki-67 proliferation activity was low (<1%), and were negative for Syn, CgA, S-100, AE1/AE3 and EMA. PSA staining showing clear cell borders. With a review of the literature, the clinical, pathological characteristics and treatment modalities of this rare tumor are discussed.
authors.affiliation: Department of Pathology, The Third Affiliated Hospital of Soochow University 185 Juqian Street, Changzhou 213003, P. R. China.
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Pathology, The Third Affiliated Hospital of Soochow University 185 Juqian Street, Changzhou 213003, P. R. China.
authors.forename: Jun
authors.initials: J
authors.lastname: Xie
authors.affiliation: Department of Pathology, The Third Affiliated Hospital of Soochow University 185 Juqian Street, Changzhou 213003, P. R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Tan
authors.affiliation: Department of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University Changzhou 213003, P. R. China.
authors.forename: Jingting
authors.initials: J
authors.lastname: Jiang
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D005918:Glomus Tumor / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D014134:Tracheal Neoplasms / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: Glomus tumor; differential diagnosis; immunohistochemistry; trachea