title: Clinical application value of preoperative selective partial splenic embolization before splenectomy plus portal-azygous disconnection.
abstract: The aim of this study is to explore the clinical application value of preoperative selective partial splenic embolization before splenectomy plus portal-azygous disconnection. 158 cases of liver cirrhosis combined with upper gastrointestinal hemorrhage patients were selected, which were randomly divided into splenic embolization group (S, n=77) and the non-splenic embolization group (U, n=81). Group S patients were firstly performed partial splenic embolization (PSE), and then underwent splenectomy plus portal-azygous disconnection, and the group U patients were directly performed splenectomy plus portal-azygous disconnection. Statistical analysis was used SAS8.0 statistical analysis software. One week after partial splenic embolization, the platelet of group S returned to normal, and the rise of white blood cells and hemoglobin, and shorten of prothrombin time in group S were much better than that in group U (P<0.01, P<0.05); the indexes, such as the intraoperative blood loss, the blood transfusion amount, the amount of platelet infusion, and the incidence of complications in group S were more superior than that in group U (P<0.05). Preoperative selective splenic artery embolization before splenectomy plus portal-azygous disconnection can restore the spleen function, and reduce the risk of surgery and incidence of complications.
authors.affiliation: Department of The Second General Surgery, People's Hospital of Zhengzhou Zhengzhou 450053, Henan, China.
authors.forename: Shengxing
authors.initials: S
authors.lastname: Zhu
authors.affiliation: Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 430030, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Chang
mesh_terms: D000328:Adult; D000368:Aged; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology / Q000601:surgery; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D011300:Preoperative Care / Q000009:adverse effects / Q000379:methods*; D013156:Splenectomy / Q000379:methods*
keywords: Liver cirrhosis; hypersplenism; splenectomy; splenic embolization; the portal-azygous disconnection