title: The Association of Individual and Regional Socioeconomic Status on Initial Peritonitis and Outcomes in Peritoneal Dialysis Patients: A Propensity Score-Matched Cohort Study.
abstract: ♦
  
  
  
  Research indicates that the socioeconomic status (SES) of individuals and the area where they live are related to initial peritonitis and outcomes in peritoneal dialysis (PD). We conducted a retrospective, multi-center cohort study in China to examine these associations. ♦
  
  
  
  Data on 2,171 PD patients were collected from 7 centers, including baseline demographic, socioeconomic, and laboratory data. We explored the potential risk factors for initial peritonitis and outcomes using univariate Cox regression and unadjusted binary logistic regression. Then, we used propensity score matching to balance statistically significant risk factors for initial peritonitis and outcomes, and Kaplan-Meier survival analysis to compare differences in peritonitis-free rates between different groups of participants after matching. ♦
  
  
  
  A total of 563 (25.9%) initial episodes of peritonitis occurred during the study period. The Kaplan-Meier peritonitis-free rate curve showed high-income patients had a significantly lower risk than low-income patients (p = 0.007) after matching for age, hemoglobin, albumin, and regional SES and PD center. The risk of treatment failure was significantly lower in the high-income than the low-income group after matching for the organism causing peritonitis and PD center: odds ratio (OR) = 0.27 (0.09 - 0.80, p = 0.018). Regional SES and education were not associated with initial peritonitis and outcomes. ♦
  
  
  
  Our study demonstrates low individual income is a risk factor for the initial onset of peritonitis and treatment failure after initial peritonitis.
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Harbin Medical University, Heilongjiang, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Harbin Medical University, Heilongjiang, China.
authors.forename: Ke-Jie
authors.initials: KJ
authors.lastname: Hu
authors.affiliation: Department of Nephrology, Second Affiliated Hospital of Harbin Medical University, Heilongjiang, China renyeping123@126.com.
authors.forename: Ye-Ping
authors.initials: YP
authors.lastname: Ren
authors.affiliation: Renal Division, Department of Medicine, Peking University First Hospital, and Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, and Key Laboratory of Chronic Kidney Disease Prevention and Treatment (Peking University), Ministry of Education, Beijing, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Dong
authors.affiliation: Department of Nephrology, Peking University Third Hospital, Beijing, China.
authors.forename: Qing-Feng
authors.initials: QF
authors.lastname: Han
authors.affiliation: Department of Nephrology, Huashan Hospital of Fudan University, Shanghai, China.
authors.forename: Tong-Ying
authors.initials: TY
authors.lastname: Zhu
authors.affiliation: Kidney Disease Center, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Jiang-Hua
authors.initials: JH
authors.lastname: Chen
authors.affiliation: Department of Nephrology, Peking University People's Hospital, Beijing, China.
authors.forename: Hui-Ping
authors.initials: HP
authors.lastname: Zhao
authors.affiliation: Department of Nephrology, General Hospital of Ningxia Medical University, Ningxia, China.
authors.forename: Meng-Hua
authors.initials: MH
authors.lastname: Chen
authors.affiliation: Renal Division, Department of Medicine, Peking University First Hospital, and Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, and Key Laboratory of Chronic Kidney Disease Prevention and Treatment (Peking University), Ministry of Education, Beijing, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Xu
authors.affiliation: Department of Nephrology, Peking University Third Hospital, Beijing, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Nephrology, Huashan Hospital of Fudan University, Shanghai, China.
authors.forename: Chuan-Ming
authors.initials: CM
authors.lastname: Hao
authors.affiliation: Kidney Disease Center, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
authors.forename: Xiao-Hui
authors.initials: XH
authors.lastname: Zhang
authors.affiliation: Department of Nephrology, Peking University People's Hospital, Beijing, China.
authors.forename: Mei
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Nephrology, General Hospital of Ningxia Medical University, Ningxia, China.
authors.forename: Na
authors.initials: N
authors.lastname: Tian
authors.affiliation: Renal Division, Department of Medicine, Peking University First Hospital, and Institute of Nephrology, Peking University, Key Laboratory of Renal Disease, Ministry of Health of China, and Key Laboratory of Chronic Kidney Disease Prevention and Treatment (Peking University), Ministry of Education, Beijing, China.
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D002681:China; D004522:Educational Status; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007676:Kidney Failure, Chronic / Q000628:therapy*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010538:Peritonitis / Q000453:epidemiology*; D057216:Propensity Score; D012189:Retrospective Studies; D012307:Risk Factors; D012923:Social Class; D016896:Treatment Outcome
keywords: Initial peritonitis; peritoneal dialysis; propensity score matching; socioeconomic status