title: The complete mitochondrial genome of rabbit pinworm Passalurus ambiguus: genome characterization and phylogenetic analysis.
abstract: Passalurus ambiguus (Nematda: Oxyuridae) is a common pinworm which parasitizes in the caecum and colon of rabbits. Despite its significance as a pathogen, the epidemiology, genetics, systematics, and biology of this pinworm remain poorly understood. In the present study, we sequenced the complete mitochondrial (mt) genome of P. ambiguus. The circular mt genome is 14,023 bp in size and encodes of 36 genes, including 12 protein-coding, two ribosomal RNA, and 22 transfer RNA genes. The mt gene order of P. ambiguus is the same as that of Wellcomia siamensis, but distinct from that of Enterobius vermicularis. Phylogenetic analyses based on concatenated amino acid sequences of 12 protein-coding genes by Bayesian inference (BI) showed that P. ambiguus was more closely related to W. siamensis than to E. vermicularis. This mt genome provides novel genetic markers for studying the molecular epidemiology, population genetics, systematics of pinworm of animals and humans, and should have implications for the diagnosis, prevention, and control of passaluriasis in rabbits and other animals.
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, Gansu, People's Republic of China.
authors.forename: Guo-Hua
authors.initials: GH
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, Gansu, People's Republic of China.|College of Animal Science and Technology, Yunnan Agricultural University, Kunming, 650201, Yunnan, People's Republic of China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Li
authors.affiliation: College of Animal Science and Technology, Yunnan Agricultural University, Kunming, 650201, Yunnan, People's Republic of China.
authors.forename: Feng-Cai
authors.initials: FC
authors.lastname: Zou
authors.affiliation: College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, 163319, Heilongjiang, People's Republic of China. chunrenwang@sohu.com.
authors.forename: Chun-Ren
authors.initials: CR
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, Gansu, People's Republic of China. xingquanzhu1@hotmail.com.|College of Animal Science and Technology, Yunnan Agricultural University, Kunming, 650201, Yunnan, People's Republic of China. xingquanzhu1@hotmail.com.|College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, 163319, Heilongjiang, People's Republic of China. xingquanzhu1@hotmail.com.
authors.forename: Xing-Quan
authors.initials: XQ
authors.lastname: Zhu
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001499:Bayes Theorem; D004272:DNA, Mitochondrial / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification; D004757:Enterobius / Q000145:classification / Q000235:genetics; D023061:Gene Order; D050259:Genes, Mitochondrial; D005819:Genetic Markers; D054629:Genome, Mitochondrial; D015801:Helminth Proteins / Q000737:chemistry / Q000235:genetics; D010123:Oxyuriasis / Q000469:parasitology / Q000662:veterinary*; D010124:Oxyuroidea / Q000145:classification / Q000235:genetics*; D010802:Phylogeny; D012335:RNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D012343:RNA, Transfer / Q000737:chemistry / Q000235:genetics; D011817:Rabbits / Q000469:parasitology*; D016415:Sequence Alignment
chemical_list: D004272:DNA, Mitochondrial; D005819:Genetic Markers; D015801:Helminth Proteins; D012335:RNA, Ribosomal; D012343:RNA, Transfer
keywords: Genetics; Mitochondrial genome; Phylogenetic analyses; Pinworm