title: Flavonoids modify root growth and modulate expression of SHORT-ROOT and HD-ZIP III.
abstract: Flavonoids are a class of distinct compounds produced by plant secondary metabolism that inhibit or promote plant development and have a relationship with auxin transport. We showed that, in terms of root development, Copaifera langsdorffii leaf extracts has an inhibitory effect on most flavonoid components compared with the application of exogenous flavonoids (glycosides and aglycones). These compounds alter the pattern of expression of the SHORT-ROOT and HD-ZIP III transcription factor gene family and cause morpho-physiological alterations in sorghum roots. In addition, to examine the flavonoid auxin interaction in stress, we correlated the responses with the effects of exogenous application of auxin and an auxin transport inhibitor. The results show that exogenous flavonoids inhibit primary root growth and increase the development of lateral roots. Exogenous flavonoids also change the pattern of expression of specific genes associated with root tissue differentiation. These findings indicate that flavonoid glycosides can influence the polar transport of auxin, leading to stress responses that depend on auxin.
authors.affiliation: Department of Botany, Institute of Bioscience of Botucatu, Univ. Estadual Paulista (UNESP), 18618-689 Botucatu, Sao Paulo, Brazil.
authors.forename: Danilo Miralha
authors.initials: DM
authors.lastname: Franco
authors.affiliation: Department of Biological Sciences, ESALQ/USP, 13418-260 Piracicaba, Sao Paulo, Brazil.
authors.forename: Eder Marques
authors.initials: EM
authors.lastname: Silva
authors.affiliation: Department of Botany, Institute of Bioscience of Botucatu, Univ. Estadual Paulista (UNESP), 18618-689 Botucatu, Sao Paulo, Brazil; Department of Biological Science, Science Faculty, Univ. Estadual Paulista (UNESP), 17033-360 Bauru, Sao Paulo, Brazil.
authors.forename: Luiz Leonardo
authors.initials: LL
authors.lastname: Saldanha
authors.affiliation: Department of Botany, Institute of Bioscience of Botucatu, Univ. Estadual Paulista (UNESP), 18618-689 Botucatu, Sao Paulo, Brazil.
authors.forename: Sérgio Akira
authors.initials: SA
authors.lastname: Adachi
authors.affiliation: Department of Botany, Institute of Bioscience of Botucatu, Univ. Estadual Paulista (UNESP), 18618-689 Botucatu, Sao Paulo, Brazil.
authors.forename: Thayssa Rabelo
authors.initials: TR
authors.lastname: Schley
authors.affiliation: Department of Botany, Institute of Bioscience of Botucatu, Univ. Estadual Paulista (UNESP), 18618-689 Botucatu, Sao Paulo, Brazil.
authors.forename: Tatiane Maria
authors.initials: TM
authors.lastname: Rodrigues
authors.affiliation: Department of Biological Science, Science Faculty, Univ. Estadual Paulista (UNESP), 17033-360 Bauru, Sao Paulo, Brazil.
authors.forename: Anne Ligia
authors.initials: AL
authors.lastname: Dokkedal
authors.affiliation: Department of Biological Sciences, ESALQ/USP, 13418-260 Piracicaba, Sao Paulo, Brazil.
authors.forename: Fabio Tebaldi Silveira
authors.initials: FT
authors.lastname: Nogueira
authors.affiliation: Department of Botany, Institute of Bioscience of Botucatu, Univ. Estadual Paulista (UNESP), 18618-689 Botucatu, Sao Paulo, Brazil. Electronic address: luizfernando@ibb.unesp.br.
authors.forename: Luiz Fernando
authors.initials: LF
authors.lastname: Rolim de Almeida
mesh_terms: D064089:Allelopathy / Q000187:drug effects*; D001692:Biological Transport / Q000187:drug effects; D007887:Fabaceae / Q000737:chemistry; D005419:Flavonoids / Q000494:pharmacology*; D018506:Gene Expression Regulation, Plant / Q000187:drug effects*; D007210:Indoleacetic Acids / Q000378:metabolism; D010936:Plant Extracts / Q000494:pharmacology; D010937:Plant Growth Regulators / Q000378:metabolism; D018515:Plant Leaves / Q000737:chemistry; D018517:Plant Roots / Q000187:drug effects / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D036226:Seedlings / Q000187:drug effects / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D012639:Seeds / Q000187:drug effects / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D045868:Sorghum / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development / Q000378:metabolism
chemical_list: D005419:Flavonoids; D007210:Indoleacetic Acids; D010936:Plant Extracts; D010937:Plant Growth Regulators
keywords: Allelopathic stress; Differential gene expression; Kaempferol-3-O-alpha-rhamnoside; Quercetin-3-O-alpha-rhamnoside; Root development