title: [The possibility of prenatal diagnosis of autism spectrum disorder].
abstract: Autism spectrum disorder (ASD) is an idiopathic multifactorial disease. Chromosomal abnormalities could be found only in a few percent (0.3-0.6) of cases. The estimated prevalence is 0.6 in Europe and the prevalence of the disease has been increased in last few decades. ASD have an impact on the quality of life of the patient and his family. The early diagnosis of ASD is most important. There are limited data regarding the measure of biparietal diameter (BPD) of the fetus in the first trimester of pregnancy. These data suggested the BPD is an important screening marker for ASD, but the complex prenatal screening is unresolved. There is a need for further investigations of the genetic background of ASD and to identify potentially first trimester ultrasound markers for ASD.
authors.affiliation: Szegedi Tudomanyegyetem, Szent-Gyorgyi Albert Klinikai Kozpont, Szuleszeti es Nogyogyaszati Klinika, Szeged, Hungary, E-mail: vanya.melinda@med.u-szeged.hu.
authors.forename: Melinda
authors.initials: M
authors.lastname: Vanya
authors.forename: Szabina
authors.initials: S
authors.lastname: Szücs
authors.forename: Károly
authors.initials: K
authors.lastname: Szili
authors.forename: Ágnes
authors.initials: Á
authors.lastname: Vetró
authors.forename: György
authors.initials: G
authors.lastname: Bártfai
mesh_terms: D000067877:Autism Spectrum Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D002648:Child; D002657:Child Development; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis / Q000209:etiology; D002675:Child, Preschool; D015897:Comorbidity; D042241:Early Diagnosis; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008403:Mass Screening / Q000379:methods; D010296:Parietal Lobe / Q000473:pathology*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D015995:Prevalence; D011788:Quality of Life; D012307:Risk Factors; D057566:Self Report; D012959:Socioeconomic Factors; D014743:Videotape Recording