title: [THE CHARACTERISTICS OF CYTOKINE STATUS UNDER DIFFERENT CLINICAL VARIANTS OF GLOMERULONEPHRITIS].
abstract: The article presents results of identification of indicators of cytokine status in 58 patients with glomerulonephritis using solid-phase immunoenzyme analysis. It is established that in patients with glomerulonephritis the level of pro-inflammatory and anti-inflammatory cytokines (IL-lβ, IL-2, IL-10 and Ra-IL-1β) circulating in blood is augmented. The differences are established concerning cytokine status of patients depending on clinical type of disease. The level of production of IL-10, correlating with glomerular, tubular and erythropoietic functions of kidneys significantly effected formation of various clinical types of glomerulonephritis.
authors.forename: L M
authors.initials: LM
authors.lastname: Karzakova
authors.forename: O I
authors.initials: OI
authors.lastname: Avtonomova
authors.forename: I M
authors.initials: IM
authors.lastname: Stepanova
authors.forename: N A
authors.initials: NA
authors.lastname: Komeliagina
authors.forename: S I
authors.initials: SI
authors.lastname: Kudriashov
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000097:blood* / Q000276:immunology / Q000503:physiopathology; D005923:Glomerulosclerosis, Focal Segmental / Q000097:blood* / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D007371:Interferon-gamma / Q000097:blood; D016753:Interleukin-10 / Q000097:blood; D053583:Interleukin-1beta / Q000097:blood; D007376:Interleukin-2 / Q000097:blood; D007668:Kidney / Q000276:immunology / Q000378:metabolism* / Q000503:physiopathology; D008181:Lupus Nephritis / Q000097:blood* / Q000276:immunology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D053573:Receptors, Interleukin-1 Type I / Q000097:blood
chemical_list: C508609:IL10 protein, human; D053583:Interleukin-1beta; D007376:Interleukin-2; D053573:Receptors, Interleukin-1 Type I; D016753:Interleukin-10; D007371:Interferon-gamma