title: Novel Risk Factors for Type 2 Diabetes in African-Americans.
abstract: In the USA, compared to whites, African-Americans are disproportionately impacted by the diabetes epidemic. Traditional diabetes risk factors, such as obesity, are more common among African-Americans, but these traditional risk factors do not explain all of the disparity in diabetes risk. Recent research has identified novel environmental, lifestyle, physiologic, and genetic risk factors for diabetes, some of which appear to impact African-Americans more than whites. This manuscript reviews the recent literature to highlight some of these novel risk factors that may be contributing to the racial disparity in diabetes risk. Further study is needed of the modifiable risk factors for development of interventions to reduce the risk of diabetes in African-Americans, as well as other high-risk populations.
authors.affiliation: Division of General Internal Medicine, Duke University, 411 West Chapel Hill Street, Suite 500, Durham, NC, 27701, USA. ranee.chatterjee@duke.edu.
authors.forename: Ranee
authors.initials: R
authors.lastname: Chatterjee
authors.affiliation: Division of General Internal Medicine, Johns Hopkins University, 2024 E Monument St., Baltimore, MD, 21287, USA. maruthur@jhmi.edu.
authors.forename: Nisa M
authors.initials: NM
authors.lastname: Maruthur
authors.affiliation: Division of General Internal Medicine, Duke University, 411 West Chapel Hill Street, Suite 500, Durham, NC, 27701, USA. david.edelman@duke.edu.
authors.forename: David
authors.initials: D
authors.lastname: Edelman
mesh_terms: D001741:Black or African American; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000208:ethnology*; D004032:Diet; D005247:Feeding Behavior; D006801:Humans; D009765:Obesity / Q000209:etiology; D012307:Risk Factors; D014481:United States / Q000208:ethnology; D044465:White People
keywords: Diabetes risk; Novel risk factors; Racial disparity