title: Rhodium(II)-Catalyzed Formal [3 + 2] Cycloaddition of N-Sulfonyl-1,2,3-triazoles with Isoxazoles: Entry to Polysubstituted 3-Aminopyrroles.
abstract: A novel rhodium(II)-catalyzed formal [3 + 2] cycloaddition of N-sulfonyl-1,2,3-triazoles with isoxazoles has been achieved that provides an efficient method for the synthesis of polysubstituted 3-aminopyrrole derivatives. An operationally simple one-pot synthesis of the titled compounds from terminal alkynes, tosyl azide, and isoxazoles was also developed. The presented reaction affords an illustrative example of employing 1,2,3-triazoles as the [2C]-component in relevant cycloaddition reactions.
authors.affiliation: College of Chemistry, Chemical Engineering and Environmental Engineering, Liaoning Shihua University , Dandong Lu West 1, Fushun 113001, China.|Comprehensive AIDS Research Center, Department of Pharmacology & Pharmaceutical Sciences, School of Medicine, Tsinghua University , Beijing 100084, China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Lei
authors.affiliation: Comprehensive AIDS Research Center, Department of Pharmacology & Pharmaceutical Sciences, School of Medicine, Tsinghua University , Beijing 100084, China.
authors.forename: Longbo
authors.initials: L
authors.lastname: Li
authors.affiliation: College of Chemistry, Chemical Engineering and Environmental Engineering, Liaoning Shihua University , Dandong Lu West 1, Fushun 113001, China.
authors.forename: Yu-Peng
authors.initials: YP
authors.lastname: He
authors.affiliation: Comprehensive AIDS Research Center, Department of Pharmacology & Pharmaceutical Sciences, School of Medicine, Tsinghua University , Beijing 100084, China.|Collaborative Innovation Center for Biotherapy, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University , Chengdu 610041, China.
authors.forename: Yefeng
authors.initials: Y
authors.lastname: Tang