title: The vitamin D status and its effects on life quality among the elderly in Jinan, China.
abstract: A challenge for researchers is that vitamin D has many functions in the body, and vitamin D status across the world is not optimistic. There was little data regarding insufficient vitamin D status and its adverse effect on health of elderly Chinese people. So we selected 686 subjects (310 men and 376 women) aged 60-89 years to explore the correlation between vitamin D status and their life quality in a community-based osteoporosis prevention study at Qianfoshan Hospital of Shandong University from 2009 to 2010. All subjects were divided into three groups: vitamin D adequacy [serum 25(OH)D ≧ 75 nmol/L], hypovitaminosis D (50-74.9 nmol/L), and vitamin D insufficiency (<50 nmol/L). Participants were requested to complete SF-36 health survey. The regression models were used to evaluate respectively the association between 25(OH)D levels and parameters of SF-36. As a result, serum 25(OH)D levels were 58.60 nmol/L in male [95% confidence interval (95% CI): 56.7-60.5 nmol/L] and 54.17 nmol/L in female (95% CI: 52.8-55.8 nmol/L). Vitamin D adequacy was in 19.4% of male and 14.4% of female. With aging, proportions of insufficient vitamin D increased significantly in male (P=0.004), and in female (P<0.001). The elderly with hypovitaminosis D got lower scores than that with vitamin D adequacy (almost P<0.01). Regression analysis showed that vitamin D appeared a positive association with parameters of SF-36 (almost P<0.001). In conclusion, vitamin D status in the elderly was severely inadequate, which decreased their life quality and cause adverse effect on their health.
authors.affiliation: Department of Endocrinology, Qianfoshan Hospital, Shandong University, Jinan 250014, China.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Feng
authors.affiliation: Department of Endocrinology, Qianfoshan Hospital, Shandong University, Jinan 250014, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Guo
authors.affiliation: Department of Endocrinology, Qianfoshan Hospital, Shandong University, Jinan 250014, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Endocrinology, Qianfoshan Hospital, Shandong University, Jinan 250014, China. Electronic address: kdh_2011@hotmail.com.
authors.forename: Donghong
authors.initials: D
authors.lastname: Kang
authors.affiliation: Department of Endocrinology, Qianfoshan Hospital, Shandong University, Jinan 250014, China.
authors.forename: Xuanqiang
authors.initials: X
authors.lastname: Che
authors.affiliation: Department of Endocrinology, Qianfoshan Hospital, Shandong University, Jinan 250014, China.
authors.forename: Hongmei
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Endocrinology, Qianfoshan Hospital, Shandong University, Jinan 250014, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Cao
authors.affiliation: Department of Endocrinology, Qianfoshan Hospital, Shandong University, Jinan 250014, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
mesh_terms: D015652:25-Hydroxyvitamin D 2 / Q000097:blood*; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood* / Q000523:psychology; D044466:Asian People / Q000523:psychology* / Q000706:statistics & numerical data; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life; D012044:Regression Analysis; D012111:Residence Characteristics; D014808:Vitamin D Deficiency / Q000097:blood* / Q000453:epidemiology / Q000523:psychology*
chemical_list: D015652:25-Hydroxyvitamin D 2
keywords: Elderly; Health; Hypovitaminosis; Insufficiency; Vitamin D