title: Pregnancy outcomes in substance-misusing pregnant women: A 10-year retrospective study.
abstract: In this ten-year retrospective study we were able to show that Maltese substance-misusing mothers (SMMs) have significantly different socio-biological characteristics from mothers in the general population which seem to impact on neonatal outcomes. Significant differences from the general population were noted in the SMM's age, age at first pregnancy, marital status, educational background, number of cigarettes smoked, number of offspring and weight gained in pregnancy. SMMs booked their pregnancy in hospital later than the general population. On the other hand their infants had a lower mean birth weight and head circumference, had lower Apgar scores, were of lesser gestational age and premature. They were less breast-fed and stayed longer in hospital after their birth.
authors.affiliation: a Sedqa, National Agency for Addiction, Substance Misuse Out-Patients Unit, St Luke's Hospital , Guardamangia , Malta.|b Institute of Pharmaceutical Science, King's College London , London , UK.
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Vella
authors.affiliation: c Department of Obstetrics and Gynaecology , University of Malta.
authors.forename: Charles
authors.initials: C
authors.lastname: Savona Ventura
authors.affiliation: d Institute of Pharmaceutical Science, King's College London , UK.
authors.forename: Kim
authors.initials: K
authors.lastname: Wolff
mesh_terms: D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D004522:Educational Status; D005260:Female; D005865:Gestational Age; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008319:Malta; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced*; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000139:chemically induced; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D012959:Socioeconomic Factors; D019966:Substance-Related Disorders / Q000150:complications*; D055815:Young Adult
keywords: Malta; Pregnancy; methadone; substance misuse