title: Do Placental Histopathologic Characteristics Differ with Gestational Ages in Preterm and Term Deliveries?
abstract: The study aim is to evaluate the placental histopathological characteristics and maternal risk factors in preterm and term births according to their weeks of gestation. We designed a prospective study involving a patient population (n = 355) composed of pregnant women who delivered preterm (n = 216) and term neonates (n = 139). The preterm births were divided into three groups as extremely (n = 22), moderate (n = 96) and late preterm (n = 98) births. The statistical analyses were performed using SPSS version 15 software. There was significant difference regarding maternal vascular underperfusion and inflammation in the extremely preterm group compared with the other groups (P = 0.001), but fetal vascular obstruction and villitis of unknown etiology were not found significantly different. According to our study results, the careful examination of the placenta of premature babies, particularly those of extremely preterm births, should be part of routine obstetrical management to determine the causes of preterm birth.
authors.affiliation: a Obstetrics and Gynecology, Bakirkoy Dr Sadi Konuk Teaching and Research Hospital , Istanbul , Turkey.
authors.forename: Keziban
authors.initials: K
authors.lastname: Doğan
authors.affiliation: b Neonatal Intensive Care Unit, Department of Pediatrics , Bakirkoy Dr Sadi Konuk Teaching and Research Hospital , Istanbul , Turkey.
authors.forename: Ozgul
authors.initials: O
authors.lastname: Salihoglu
authors.affiliation: c Pathology, Bakirkoy Dr Sadi Konuk Teaching and Research Hospital , Istanbul , Turkey.
authors.forename: Nurten
authors.initials: N
authors.lastname: Sever
authors.affiliation: a Obstetrics and Gynecology, Bakirkoy Dr Sadi Konuk Teaching and Research Hospital , Istanbul , Turkey.
authors.forename: Tuba
authors.initials: T
authors.lastname: Tombul
authors.affiliation: d Department of Pediatrics , Bakirkoy Dr Sadi Konuk Teaching and Research Hospital , Istanbul , Turkey.
authors.forename: Ergül
authors.initials: E
authors.lastname: Sari
authors.affiliation: a Obstetrics and Gynecology, Bakirkoy Dr Sadi Konuk Teaching and Research Hospital , Istanbul , Turkey.
authors.forename: Levent
authors.initials: L
authors.lastname: Yaşar
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D047928:Premature Birth / Q000473:pathology*; D011446:Prospective Studies; D047929:Term Birth
keywords: Placenta; histopathology; neonate; pregnancy; preterm birth; term birth