title: Management status and its predictive factors in patients with type 2 diabetes in China: A Nationwide Multicenter Study: A Nationwide Multicenter Study.
abstract: BACKGROUND
  The prevalence of type 2 diabetes in China is increasing rapidly. Appropriate management of glycemia, blood pressure and dyslipidemia in this population is a major public health concern.
  
  
  OBJECTIVE
  The aim of this study was to assess metabolic control including glycated hemoglobin A1c (HbA1c ), blood pressure (BP) and low density lipoprotein cholesterol (LDL-c), in a large sample of patients with type 2 diabetes in China and to identify factors that correlated with the achievement of HbA1c, BP and LDL-c goals (ABCs).
  
  
  METHODS
  A nationwide survey was conducted in 50 medical centres across China from April to July of 2010. Baseline information on demographics, medical history, HbA1c , BP and LDL-c levels were measured in 5961 patients with type 2 diabetes.
  
  
  RESULTS
  Mean age, body mass index (BMI) and HbA1c were 59.5 ± 1.3 years, 24.5 ± 4.1 kg/m(2) and 8.3 ± 2.2%, respectively. With respect to generally accepted ABC treatment goals, 35.2% of participants had HbA1c <7%; 35.5% had BP < 140/80 mmHg, and 45.1% had LDL-c < 100 mg/dl. The proportion of patients who met all three targets was only 5.4%. Logistic regression revealed that smoking (P=0.000), higher BMI (P=0.001) and insulin use (P=0.000) were statistically significant predictors of failing to meet ABC targets.
  
  
  CONCLUSIONS
  The percentage of Chinese patients with type 2 diabetes who met recommended targets for HbA1c , BP and LDL-c in 2010 was low. Smoking, higher BMI and insulin use were the strongest determinants of failing to meet ABC targets.
authors.affiliation: Jiangsu Province Hospital on Integration of Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Liu
authors.affiliation: Jiangsu Province Hospital on Integration of Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
authors.forename: Qingqing
authors.initials: Q
authors.lastname: Lou
authors.affiliation: Department of Endocrinology, Peking University First Hospital, #8 Xishiku Street, Beijing, China.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Guo
authors.affiliation: Department of Endocrinology, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, China.
authors.forename: Li
authors.initials: L
authors.lastname: Yuan
authors.affiliation: Department of Endocrinology, Peking University First Hospital, Beijing, 100034, China.
authors.forename: Li
authors.initials: L
authors.lastname: Shen
authors.affiliation: Institute of Diabetes, Zhongda Hospital, Medical School, Southeast University, Nanjing, Jiangsu, 210009, China.
authors.forename: Zilin
authors.initials: Z
authors.lastname: Sun
authors.affiliation: Department of Endocrinology, China-Japan Friendship Hospital, Beijing, 100029, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Zhao
authors.affiliation: Department of Endocrinology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, 530021, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Dai
authors.affiliation: Nursing Department, Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Huang
authors.affiliation: Department of Endocrinology, Metabolism, First Affiliated Hospital of Kunming Medical College, Kunming, Yunnan, 650032, China.
authors.forename: Huiying
authors.initials: H
authors.lastname: Yang
authors.affiliation: UMass Medical School, 364 Plantation Street LRB 222, Worcester.
authors.forename: John P
authors.initials: JP
authors.lastname: Mordes
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis*; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002681:China; D008078:Cholesterol, LDL / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000188:drug therapy; D019468:Disease Management; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012907:Smoking
chemical_list: D001786:Blood Glucose; D008078:Cholesterol, LDL; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: blood pressure; cholesterol; hemoglobin A1c; type 2 diabetes