title: Quality of Life Assessment Using EuroQOL EQ-5D Questionnaire in Patients with Deep Infiltrating Endometriosis: The Relation with Symptoms and Locations.
abstract: The objective of this study was to evaluate the quality of life (QOL) of patients with deep infiltrating endometriosis (DIE) using EuroQOL (EQ-5D) and its correlation with symptoms and locations of endometriotic lesions. One hundred and fifty-nine patients referred for DIE from January 2011 to April 2011 were prospectively invited to complete questionnaires evaluating symptoms associated with endometriosis as well as the EQ-5D questionnaire and health state. Patients also had locations of DIE evaluated by clinical examination and magnetic resonance imaging (MRI). All 159 patients completed the questionnaires. Item response rate was 91.1%. The most intense symptoms were dysmenorrhea (7.1/10), painful defecation (6.3/10), and fatigue (6.0/10). Mean (SD) scores were 77 (14) for the EQ-5D questionnaire and 63.4 (21) for the health state. A relation was observed between the EQ-5D questionnaire and the presence of dysmenorrhea, dyspareunia, cyclic pelvic pain, painful defecation, and diarrhea or constipation. Vaginal and rectal infiltrations were significantly associated with altered EQ-5D and health state scores. The EQ-5D questionnaire is easy to complete and well related to symptoms of DIE. Rectal and vaginal infiltrations were found to be determinant factors of altered QOL by the EQ-5D questionnaire and health state.
authors.affiliation: Service de Gynécologie-Obstétrique, GRC-UPMC 6: Centre Expert en Endometriose (C3E), Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris VI, 4 rue de la Chine, 75020 Paris, France ; Service de Gynécologie-Obstétrique, Hôpital Tenon, 4 rue de la Chine, 75020 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Touboul
authors.affiliation: Service de Gynécologie-Obstétrique, GRC-UPMC 6: Centre Expert en Endometriose (C3E), Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris VI, 4 rue de la Chine, 75020 Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Amate
authors.affiliation: Service de Gynécologie-Obstétrique, GRC-UPMC 6: Centre Expert en Endometriose (C3E), Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris VI, 4 rue de la Chine, 75020 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Ballester
authors.affiliation: Service de Radiologie, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris VI, 4 rue de la Chine, 75020 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Bazot
authors.affiliation: Service de Gynécologie-Obstétrique, Centre Hospitalier Interrégional de Poissy, Université Paris XIV Saint Quentin en Yvelynes, 10 Rue du Champ Gaillard, 78300 Poissy, France.
authors.forename: A
authors.initials: A
authors.lastname: Fauconnier
authors.affiliation: Service de Gynécologie-Obstétrique, GRC-UPMC 6: Centre Expert en Endometriose (C3E), Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris VI, 4 rue de la Chine, 75020 Paris, France ; Service de Gynécologie-Obstétrique, Hôpital Tenon, 4 rue de la Chine, 75020 Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Daraï