title: Retrograde intrarenal surgery for urinary stone disease in patients with solitary kidney: A retrospective analysis of the efficacy and safety.
abstract: OBJECTIVE
  To compare outcomes of retrograde intrarenal surgery for urolithiasis between patients with solitary kidneys and patients who have single-side urolithiasis with bilateral kidneys.
  
  
  METHODS
  We retrospectively analyzed outcomes of retrograde intrarenal surgery in solitary kidney patients (group A) carried out during 2007-2014, and in patients with bilateral kidneys with comparable stone burdens (group B). Stone-free status was defined as no residual fragment on computed tomography 1 month later.
  
  
  RESULTS
  There were 19 patients in group A (mean age 62.5 ± 18.4 years, range 14-76 years). The mean stone diameter and burden were 6.0 mm (range 3-24 mm) and 10.42 ± 6.92 mm, respectively. The stone-free rate was 94.7%, and no repeat procedure was required. The glomerular filtration rate tended to rise post-surgery (postoperative day 1: 48.67 ± 15.92 mL/min, 100.2%, P = 0.940; postoperative month 1: 51.32 ± 16.90 mL/min, 105.7%, P = 0.101) compared with preoperative rates. The stone-free rate and surgery time were not significantly different between the two groups, although post-surgical hospitalization time was longer for group A (4.05 vs 3.08 days, P = 0.037). The change in glomerular filtration rate was not significantly different between groups A and B (postoperative day 1: +0.101 vs +0.547 mL/min, respectively, P = 0.857; postoperative month 1: +2.749 vs 3.161 mL/min, respectively, P = 0.882). No significant difference was found in terms of complication rate.
  
  
  CONCLUSIONS
  Retrograde intrarenal surgery in solitary kidney patients is as safe and effective as in bilateral kidney patients.
authors.affiliation: Department of Urology, Ohguchi Higashi General Hospital, Yokohama, Kanagawa, Japan.
authors.forename: Shinnosuke
authors.initials: S
authors.lastname: Kuroda
authors.affiliation: Department of Urology, Ohguchi Higashi General Hospital, Yokohama, Kanagawa, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Fujikawa
authors.affiliation: Department of Urology, Ohguchi Higashi General Hospital, Yokohama, Kanagawa, Japan.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Tabei
authors.affiliation: Department of Urology, Ohguchi Higashi General Hospital, Yokohama, Kanagawa, Japan.|Department of Urology, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Ito
authors.affiliation: Department of Urology, Ohguchi Higashi General Hospital, Yokohama, Kanagawa, Japan.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Terao
authors.affiliation: Department of Urology, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yao
authors.affiliation: Department of Urology, Ohguchi Higashi General Hospital, Yokohama, Kanagawa, Japan.
authors.forename: Junichi
authors.initials: J
authors.lastname: Matsuzaki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000503:physiopathology / Q000601:surgery*; D007669:Kidney Calculi / Q000601:surgery*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D012189:Retrospective Studies; D016896:Treatment Outcome; D013520:Urologic Surgical Procedures / Q000009:adverse effects; D055815:Young Adult
keywords: calculi; glomerular filtration rate; retrograde intrarenal surgery; solitary kidney; urolithiasis