title: [THE APPLICATION OF TECHNOLOGY OF IMMUNE CHIPS FOSFANTM FOR INVESTIGATION OF MARKERS OF THYROID GLAND].
abstract: The set of reagents was developed on the basis of technology of immune chips in flatbed format FOSFANTM to apply in multiplex detection of markers of functional state of thyroid gland. It is demonstrated that the set permits carrying out quantitative measurements of level of free thyroxine and thyrotropic hormone in human blood serum within clinically valuable ranges of concentration. The high sensitivity and good concordance with results of immune enzyme analysis under examination of clinical samples were demonstrated.
authors.forename: N I
authors.initials: NI
authors.lastname: Beckman
authors.forename: S Yu
authors.initials: SY
authors.lastname: Laritcheva
authors.forename: T A
authors.initials: TA
authors.lastname: Bichenkova
authors.forename: V G
authors.initials: VG
authors.lastname: Pomelova
authors.forename: N S
authors.initials: NS
authors.lastname: Osin
mesh_terms: D015415:Biomarkers / Q000097:blood; D006801:Humans; D046228:Microarray Analysis / Q000295:instrumentation* / Q000379:methods*; D013961:Thyroid Gland / Q000378:metabolism*; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*
chemical_list: D015415:Biomarkers; D013972:Thyrotropin; D013974:Thyroxine