title: Isoniazid Induced Metabolic Acidosis and Renal Dysfunction in an Elderly Patient with Chronic Renal Disease.
abstract: Metabolic acidosis is one of the common manifestations of Isoniazid toxicity but rare with normally used doses of the drug. Among anti tubercular drugs, rifampicin, streptomycin and capreomycin are commonly implicated in renal injury. Here we report the first case of metabolic acidosis and renal injury caused by isoniazid at normal prescribed dose.
authors.forename: Upinder
authors.initials: U
authors.lastname: Kaur
authors.forename: Sankha S
authors.initials: SS
authors.lastname: Chakrabarti
authors.affiliation: Division of Geriatrics, Department of General Medicine Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, UP, India. iac2k10@gmail.com.
authors.forename: Indrajeet S
authors.initials: IS
authors.lastname: Gambhir
mesh_terms: D000138:Acidosis / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis*; D000368:Aged; D000995:Antitubercular Agents / Q000009:adverse effects*; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects*; D008297:Male; D051436:Renal Insufficiency, Chronic / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis*
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid