title: An unusual lipomatous brain mass in a Golden Retriever dog.
abstract: A 9-year-old Golden Retriever dog was presented to the Veterinary Medical Center with a 3-week history of grand mal seizures and was subsequently euthanized. At autopsy, a discrete, firm, expansile mass was found in the right pyriform lobe, which compressed the ipsilateral hippocampus, thalamus, and cerebral cortex. Histologically, the mass was composed of well-differentiated adipose tissue supported by fibrous and mucinous stroma. Adipocytes exhibited strong immunoreactivity for vimentin and were negative for pancytokeratin (AE1/AE3), glial fibrillary acidic protein, neuron-specific enolase, and synaptophysin. These findings are most compatible with an intracranial lipomatous hamartoma, which is an extraparenchymal lesion that has been identified in several species. The current report describes an intracerebral lipomatous hamartoma in a veterinary species.
authors.affiliation: Prairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada (Godson)Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Scott, Elliot, Philibert, Singh, Simko)True North Veterinary Diagnostics Inc., Langley, British Columbia, Canada (Scott)University of Melbourne, Melbourne, Australia (Summers) steven.scott@usask.ca.
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Scott
authors.affiliation: Prairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada (Godson)Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Scott, Elliot, Philibert, Singh, Simko)True North Veterinary Diagnostics Inc., Langley, British Columbia, Canada (Scott)University of Melbourne, Melbourne, Australia (Summers).
authors.forename: Kirsty
authors.initials: K
authors.lastname: Elliot
authors.affiliation: Prairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada (Godson)Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Scott, Elliot, Philibert, Singh, Simko)True North Veterinary Diagnostics Inc., Langley, British Columbia, Canada (Scott)University of Melbourne, Melbourne, Australia (Summers).
authors.forename: Helene
authors.initials: H
authors.lastname: Philibert
authors.affiliation: Prairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada (Godson)Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Scott, Elliot, Philibert, Singh, Simko)True North Veterinary Diagnostics Inc., Langley, British Columbia, Canada (Scott)University of Melbourne, Melbourne, Australia (Summers).
authors.forename: Brian A
authors.initials: BA
authors.lastname: Summers
authors.affiliation: Prairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada (Godson)Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Scott, Elliot, Philibert, Singh, Simko)True North Veterinary Diagnostics Inc., Langley, British Columbia, Canada (Scott)University of Melbourne, Melbourne, Australia (Summers).
authors.forename: Dale
authors.initials: D
authors.lastname: Godson
authors.affiliation: Prairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada (Godson)Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Scott, Elliot, Philibert, Singh, Simko)True North Veterinary Diagnostics Inc., Langley, British Columbia, Canada (Scott)University of Melbourne, Melbourne, Australia (Summers).
authors.forename: Baljit
authors.initials: B
authors.lastname: Singh
authors.affiliation: Prairie Diagnostic Services Inc., Saskatoon, Saskatchewan, Canada (Godson)Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Scott, Elliot, Philibert, Singh, Simko)True North Veterinary Diagnostics Inc., Langley, British Columbia, Canada (Scott)University of Melbourne, Melbourne, Australia (Summers).
authors.forename: Elemir
authors.initials: E
authors.lastname: Simko
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D006222:Hamartoma / Q000473:pathology / Q000662:veterinary*; D008297:Male; D066195:Piriform Cortex / Q000473:pathology*
keywords: Brain; choristoma; dogs; hamartoma; lipoma; mass; neuropathology; seizures