title: Emerging Technologies for Next-Generation Point-of-Care Testing.
abstract: Considerable advances in point-of-care testing (POCT) devices stem from innovations in cellphone (CP)-based technologies, paper-based assays (PBAs), lab-on-a-chip (LOC) platforms, novel assay formats, and strategies for long-term reagent storage. Various commercial CP platforms have emerged to provide cost-effective mobile health care and personalized medicine. Such assay formats, as well as low-cost PBAs and LOC-based assays, are paving the way to robust, automated, simplified, and cost-effective POCT. Strategies have also been devised to stabilize reagent storage and usage at ambient temperature. Nevertheless, successful commercialization and widespread implementation of such clinically viable technologies remain subject to several challenges and pending issues.
authors.affiliation: Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Strasse 22, D-81675 Munich, Germany. Electronic address: sandeep.vashist@tum.de.
authors.forename: Sandeep Kumar
authors.initials: SK
authors.lastname: Vashist
authors.affiliation: Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Strasse 22, D-81675 Munich, Germany.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Luppa
authors.affiliation: Micro/Nanophysics Research Laboratory, RMIT University, Melbourne, VIC 3001, Australia.
authors.forename: Leslie Y
authors.initials: LY
authors.lastname: Yeo
authors.affiliation: Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA; Bioengineering Department, University of California, Los Angeles, CA 90095, USA; California NanoSystems Institute (CNSI), University of California, Los Angeles, CA 90095, USA.
authors.forename: Aydogan
authors.initials: A
authors.lastname: Ozcan
authors.affiliation: Innovative Chromatography Group, Irish Separation Science Cluster (ISSC), Department of Chemistry and Analytical, Biological Chemistry Research Facility (ABCRF), University College Cork, Cork, Ireland. Electronic address: j.luong@ucc.ie.
authors.forename: John H T
authors.initials: JHT
authors.lastname: Luong
mesh_terms: D003955:Diagnostic Tests, Routine / Q000379:methods*; D006801:Humans; D000067716:Point-of-Care Testing
keywords: assays; cellphone; lab on a chip; paper; point-of-care testing; reagent storage