title: Plant-Specific Features of Ribosome Biogenesis.
abstract: The biogenesis of eukaryotic ribosomes is a fundamental process involving hundreds of ribosome biogenesis factors (RBFs) in three compartments of the cell, namely the nucleolus, nucleus, and cytoplasm. Many RBFs are involved in the processing of the primary ribosomal (r)RNA transcript, in which three of the four rRNAs are imbedded. While pre-rRNA processing is well described for yeast and mammals, a detailed processing scheme for plants is lacking. Here, we discuss the emerging scheme of pre-rRNA processing in Arabidopsis thaliana in comparison to other eukaryotes, with a focus on plant characteristics. In addition, we highlight the impact of the ribosome and its biogenesis on developmental processes because common phenotypes can be observed for ribosomal protein and RBF mutants.
authors.affiliation: Department of Biosciences, Molecular Cell Biology of Plants, Goethe University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany.
authors.forename: Benjamin L
authors.initials: BL
authors.lastname: Weis
authors.affiliation: Department of Biosciences, Molecular Cell Biology of Plants, Goethe University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany.
authors.forename: Jelena
authors.initials: J
authors.lastname: Kovacevic
authors.affiliation: Department of Biosciences, Molecular Cell Biology of Plants, Goethe University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany; Current address: Sanofi-Aventis GmbH, Industriepark Höchst, K703, 65926 Frankfurt am Main, Germany.
authors.forename: Sandra
authors.initials: S
authors.lastname: Missbach
authors.affiliation: Department of Biosciences, Molecular Cell Biology of Plants, Goethe University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany; Cluster of Excellence Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany; Buchman Institute for Molecular Life Sciences, Max-von-Laue-Str. 15, 60438 Frankfurt am Main, Germany. Electronic address: schleiff@bio.uni-frankfurt.de.
authors.forename: Enrico
authors.initials: E
authors.lastname: Schleiff
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000502:physiology*; D001678:Organelle Biogenesis; D012322:RNA Precursors / Q000235:genetics* / Q000378:metabolism; D018749:RNA, Plant / Q000235:genetics* / Q000378:metabolism; D012269:Ribosomal Proteins / Q000378:metabolism; D012270:Ribosomes / Q000235:genetics / Q000502:physiology*
chemical_list: D012322:RNA Precursors; D018749:RNA, Plant; D012269:Ribosomal Proteins
keywords: embryogenesis; plant development; rRNA processing; ribosome biogenesis; ribosome heterogeneity