title: Genetic drift: A case of abuse.
abstract: In this essay, an infant with multiple fractures is removed from the custody of her parents because of suspected child abuse. Subsequently studies reveal that the child has osteogenesis imperfecta, type III. Though the child is eventually returned to the mother's custody, her entire first year has been spent in foster care. The essay illustrates the toll taken on families when a diagnosis of OI is missed or delayed.
authors.forename: Robert
authors.initials: R
authors.lastname: Marion
mesh_terms: D002649:Child Abuse / Q000175:diagnosis*; D024042:Collagen Type I / Q000235:genetics; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D050723:Fractures, Bone / Q000175:diagnosis*; D000069076:Fractures, Multiple / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D010013:Osteogenesis Imperfecta / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography
chemical_list: D024042:Collagen Type I
keywords: child abuse; medical genetics; osteogenesis imperfecta; skeletal fractures