title: 1,3-Dipolar Cycloadditions of 4-Acetoxy Allenoates: Access to 2,3-Dihydropyrazoles, 2,3-Dihydroisoxazoles, and Indolizines.
abstract: The thermal 1,3-dipolar cycloadditions of 4-acetoxyallenoates 1 with various dipoles have been reported. When azomethine imines and nitrones are used as the 1,3-dipole partner, the corresponding reactions afford 2,3-dihydropyrazole and 2,3-dihydroisoxazole derivatives, respectively. These reactions might proceed via a thermal 1,3-dipolar cycloaddition and the subsequent elimination of HOAc. In addition, allenoates 1 react well with in situ generated azomethine ylides in which a similar cycloaddition pathway is followed by oxidative aromatization to give indolizine derivatives.
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology , 130 Meilong Road, Shanghai 200237, China.
authors.forename: Falin
authors.initials: F
authors.lastname: Li
authors.affiliation: Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University , 1 Gehu Road, Changzhou 213164, China.
authors.forename: Jiangfei
authors.initials: J
authors.lastname: Chen
authors.affiliation: Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University , 1 Gehu Road, Changzhou 213164, China.
authors.forename: Yading
authors.initials: Y
authors.lastname: Hou
authors.affiliation: Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University , 1 Gehu Road, Changzhou 213164, China.
authors.forename: Yujie
authors.initials: Y
authors.lastname: Li
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology , 130 Meilong Road, Shanghai 200237, China.
authors.forename: Xin-Yan
authors.initials: XY
authors.lastname: Wu
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology , 130 Meilong Road, Shanghai 200237, China.|Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University , 1 Gehu Road, Changzhou 213164, China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Tong