title: Targeting leukemia's "fatty tooth".
abstract: In this issue of Blood, Ricciardi et al report a novel fatty acid oxidation (FAO) inhibitor, ST1326, that effectively inhibits proliferation, survival, and chemoresistance in leukemia cell lines and primary samples.
authors.affiliation: CENTRE FOR DRUG RESEARCH AND DEVELOPMENT;
authors.forename: Ismael
authors.initials: I
authors.lastname: Samudio
authors.affiliation: THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER.
authors.forename: Marina
authors.initials: M
authors.lastname: Konopleva
mesh_terms: D002331:Carnitine / Q000031:analogs & derivatives*; D002334:Carnitine O-Palmitoyltransferase / Q000037:antagonists & inhibitors*; D016503:Drug Delivery Systems; D005227:Fatty Acids / Q000378:metabolism*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D009363:Neoplasm Proteins / Q000037:antagonists & inhibitors*
chemical_list: D005227:Fatty Acids; D009363:Neoplasm Proteins; D002334:Carnitine O-Palmitoyltransferase; D002331:Carnitine