title: Challenges in the successful management of a case of acute intermittent porphyria in India.
abstract: Acute intermittent porphyria (AIP) is a rare metabolic disease involving a defect in haem biosynthesis resulting in the accumulation and excessive secretion of porphyrins and its precursors. Acute attacks present with episodes of severe abdominal pain, nausea, confusion and severe life-threatening seizures. A high index of suspicion is required for the initial diagnosis of AIP.
authors.affiliation: Resident, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
authors.forename: Rushad
authors.initials: R
authors.lastname: Patell
authors.affiliation: Professor, Medical College Baroda, Vadodara, India.
authors.forename: Rupal
authors.initials: R
authors.lastname: Dosi
authors.affiliation: Assistant Professor, Medical College Baroda, Vadodara, India.
authors.forename: Harsh
authors.initials: H
authors.lastname: Joshi
authors.affiliation: Resident, Mount Sinai Icahn School of Medicine, St Luke's Roosevelt Hospital Center, NY.
authors.forename: Purav
authors.initials: P
authors.lastname: Shah
authors.affiliation: Intern, Krishna Institute of Medical Sciences, Karad, India rishi.r.tripathi@gmail.com.
authors.forename: Rishi
authors.initials: R
authors.lastname: Tripathi
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D061605:Administration, Intravenous; D000293:Adolescent; D001120:Arginine / Q000008:administration & dosage*; D006418:Heme / Q000008:administration & dosage*; D006801:Humans; D007194:India; D008297:Male; D011162:Porphobilinogen / Q000652:urine*; D017118:Porphyria, Acute Intermittent / Q000175:diagnosis* / Q000628:therapy* / Q000652:urine; D012640:Seizures; D016896:Treatment Outcome
chemical_list: D006418:Heme; D011162:Porphobilinogen; D001120:Arginine; C048849:heme arginate
keywords: Acute intermittent porphyria; human haematin