title: OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN EARLY TYPE 3 NEOVASCULARIZATION.
abstract: OBJECTIVE
  To report the imaging features of Type 3 neovascularization secondary to exudative age-related macular degeneration on optical coherence tomography angiography (OCTA).
  
  
  METHODS
  All consecutive treatment-naive patients diagnosed with early-stage Type 3 neovascularization underwent imaging by color retinal photographs or multicolor imaging, fluorescein angiography, indocyanine green angiography, spectral domain optical coherence tomography, and OCTA. The OCTA features were analyzed and correlated with the findings of conventional angiography and spectral domain optical coherence tomography.
  
  
  RESULTS
  A total of 18 treatment-naive eyes of 18 consecutive patients (13 females and 5 males; mean age 81.3 ± 6.0) were included in the analysis. Optical coherence tomography angiography showed lesions characterized by a retinal-retinal anastomosis that emerged from the deep capillary plexus, forming in all 18 eyes a clear tuft-shaped high-flow network in the outer retinal segmentation, finally abutting in the subretinal pigment epithelium space. In 15 of 18 eyes, in the choriocapillaris segmentation, there appeared a small clew-like lesion, which in 2 cases seemed connected with the choroid through a small caliber vessel.
  
  
  CONCLUSIONS
  Optical coherence tomography angiography of treatment-naive Type 3 neovascularization showed almost constantly a high-flow, tuft-shaped abnormal outer retinal proliferation, frequently associated to a small clew-like lesion in the choriocapillaris layer.
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université Paris EstCréteil, France.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Miere
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Querques
authors.forename: Oudy
authors.initials: O
authors.lastname: Semoun
authors.forename: Ala'a
authors.initials: A
authors.lastname: El Ameen
authors.forename: Vittorio
authors.initials: V
authors.lastname: Capuano
authors.forename: Eric H
authors.initials: EH
authors.lastname: Souied
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001159:Arterio-Arterial Fistula / Q000175:diagnosis* / Q000209:etiology; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D011446:Prospective Studies; D012161:Retinal Artery / Q000473:pathology*; D015861:Retinal Neovascularization / Q000145:classification / Q000175:diagnosis* / Q000209:etiology; D055213:Retinal Pigment Epithelium / Q000473:pathology; D041623:Tomography, Optical Coherence; D057135:Wet Macular Degeneration / Q000150:complications*
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green