title: Effects of Ethacrynic Acid Addition to Diet on Fitness and Development in the Psocid Liposcelis bostrychophila Badonnel.
abstract: Fertility life table provides a comprehensive description of arthropod population dynamics by the estimation of parameters about arthropod population growth potential. It can also clarify the sublethal effects of chemicals on insects. Ethacrynic acid (EA), an inhibitor of glutathione S-transferases, is a diuretic compound that has been confirmed to modulate drug resistance in organisms. In this study, the effects of EA on growth and development of Liposcelis bostrychophila Badonnel were investigated in the laboratory to explore the potential possibilities of EA as an active agent to manage insecticide-resistant psocids. The treatment of psocids was obtained by feeding on the routine diet containing 3% EA for three successive generations, and psocids on routine diet served as control. The results indicated that EA possessed some negative effects on the life-table parameters of the psocid in F1 and F2 generations. The addition of EA to diet stunted psocids growth by lengthening development time and increasing mortality with a greater effect in the F2 generation. In the third generation of psocids on EA diet, it seemed there was a return to normal. Psocid fitness was influenced by addition of EA to standard diet. Using rm values, the fitness for EA diet in F1, F2, and F3 compared with the counterpart of routine diet was calculated as 0.80, 0.74, and 0.87, respectively.
authors.affiliation: Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing 400715, P. R. China (douwei80@swu.edu.cn; 30356404@qq.com; 419093553@qq.com; weidandande@163.com; wangjinjun@swu.edu.cn).
authors.forename: Wei
authors.initials: W
authors.lastname: Dou
authors.affiliation: Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing 400715, P. R. China (douwei80@swu.edu.cn; 30356404@qq.com; 419093553@qq.com; weidandande@163.com; wangjinjun@swu.edu.cn).
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Wu
authors.affiliation: Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing 400715, P. R. China (douwei80@swu.edu.cn; 30356404@qq.com; 419093553@qq.com; weidandande@163.com; wangjinjun@swu.edu.cn).
authors.forename: Shi-Chun
authors.initials: SC
authors.lastname: Chen
authors.affiliation: Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing 400715, P. R. China (douwei80@swu.edu.cn; 30356404@qq.com; 419093553@qq.com; weidandande@163.com; wangjinjun@swu.edu.cn).
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Wei
authors.affiliation: Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing 400715, P. R. China (douwei80@swu.edu.cn; 30356404@qq.com; 419093553@qq.com; weidandande@163.com; wangjinjun@swu.edu.cn), wangjinjun@swu.edu.cn.
authors.forename: Jin-Jun
authors.initials: JJ
authors.lastname: Wang
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D004032:Diet; D004976:Ethacrynic Acid / Q000494:pharmacology*; D005298:Fertility / Q000187:drug effects; D056084:Genetic Fitness / Q000187:drug effects*; D007313:Insecta / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D015993:Life Tables
chemical_list: D004976:Ethacrynic Acid
keywords: Liposcelis bostrychophila; development; ethacrynic acid; life table