title: Synthesis of Biaryls via Benzylic C-C Bond Cleavage of Styrenes and Benzyl Alcohols.
abstract: A metal-free oxidative coupling of styrenes and benzyl alcohols with arenes has been developed for the synthesis of biaryls. The reaction features a conspicuous benzylic C-C bond cleavage of styrenes and benzyl alcohols. The reaction with both substrates proceeds through a common aldehydic intermediate formed through oxidative C-C bond cleavage of alkene and oxidation of benzyl alcohols. The reaction proceeds efficiently over a broad range of substrates with excellent functional group tolerance.
authors.affiliation: Academy of Scientific and Innovative Research and Natural Product Microbes, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-Tawi 180001, India.
authors.forename: Arvind
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Academy of Scientific and Innovative Research and Natural Product Microbes, CSIR-Indian Institute of Integrative Medicine , Canal Road, Jammu-Tawi 180001, India.
authors.forename: Bhahwal Ali
authors.initials: BA
authors.lastname: Shah