title: Comparing the Duration of Spinal Anesthesia Induced With Bupivacaine and a Bupivacaince-Lidocaine Combination in Trans-Urethral Resection of the Prostate (TURP).
abstract: BACKGROUND
  Spinal anesthesia is a safe anesthetic mode for transurethral prostate resection (TUPR). There are several studies assessing the effect of bupivacaine, lonely or accompanied by other drugs, on short duration operations. However, there is controversy regarding the exact combination.
  
  
  OBJECTIVE
  The aim of the study was to compare the effects of spinal anesthesia with bupivacaine and low dose lidocaine with bupivacaine alone on postoperative pain in those undergoing transurethral resection of prostate (TURP).
  
  
  METHODS
  This was a randomized clinical trial performed in Shiraz university of medical sciences during one year. Eighty men scheduled for TURP were randomly assigned to receive spinal anesthesia with 1.5 mL bupivacaine 0.6% and 0.6 mL Lidocaine 1% or spinal anesthesia with 1.5 mL bupivacaine 0.5% in combination with 0.6 mL normal saline. The primary endpoint was the time lag between induction of spinal anesthesia and reaching the highest spinal block level. We also recorded the duration of spinal block declining to L1 level, operation duration and the admission duration.
  
  
  RESULTS
  Both study groups were comparable regarding the baseline characteristics. We did not find any difference between the two study groups regarding the duration of anesthetic block reaching the maximum level (P = 0.433) and duration of decreasing it to L1 (P = 0.189). The course of postoperative recovery and duration of hospital admission were also comparable between the groups (P = 0.661).
  
  
  CONCLUSIONS
  Lidocaine does not have additive effects on duration and quality of spinal anesthesia with bupivacaine in those undergoing TURP.
authors.affiliation: Shiraz Anesthesiology and Critical Care Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Abdolhamid
authors.initials: A
authors.lastname: Chohedri
authors.affiliation: Shiraz Anesthesiology and Critical Care Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Raeesi Estabragh
authors.affiliation: Shiraz Anesthesiology and Critical Care Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Eghbal
authors.affiliation: Shiraz Anesthesiology and Critical Care Research Center, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Sahmeddini
authors.affiliation: Department of Oral and Maxillofacial Surgery, Shahid Rajaei Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Hamidreza
authors.initials: H
authors.lastname: Eftekharian
authors.affiliation: Student Research Committee, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Ramita
authors.initials: R
authors.lastname: Shahabifar
keywords: Bupivacaine; Lidocaine; Spinal Anesthesia