title: Signs and Symptoms of Food Allergy and Food-Induced Anaphylaxis.
abstract: Food allergies are increasing in prevalence. In order for pediatric clinicians to appropriately diagnose and manage food allergies, the characteristic signs and symptoms of these potentially severe reactions must be recognized. Unlike nonimmunologic adverse food reactions (such as lactose intolerance and food poisoning), food allergies by definition are immune-mediated responses that occur reproducibly on food ingestion. The varying clinical presentations of food allergy include IgE-mediated disorders, mixed IgE- and cell-mediated disorders, and cell-mediated food allergies. This review describes the clinical manifestations of each of these categories of food allergy, with special emphasis on recognition of food-induced anaphylaxis.
authors.affiliation: Division of Allergy and Immunology, Children's National Health System, George Washington University School of Medicine and Health Sciences, Washington, DC, USA. Electronic address: hsharma@childrensnational.org.
authors.forename: Hemant P
authors.initials: HP
authors.lastname: Sharma
authors.affiliation: Division of Allergy and Immunology, Children's National Health System, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
authors.forename: Shweta
authors.initials: S
authors.lastname: Bansil
authors.affiliation: Division of Allergy and Immunology, Children's National Health System, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
authors.forename: Burcin
authors.initials: B
authors.lastname: Uygungil
mesh_terms: D000707:Anaphylaxis / Q000175:diagnosis* / Q000276:immunology; D002648:Child; D003937:Diagnosis, Differential; D005512:Food Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007073:Immunoglobulin E / Q000276:immunology
chemical_list: D007073:Immunoglobulin E
keywords: Anaphylaxis; Food allergy; History; Presentation; Symptoms