title: Tissue Expander Placement to Prevent the Adverse Intestinal Effects of Radiotherapy in Malignant Pelvic Tumors.
abstract: We herein report the findings of 3 patients with primary Ewing sarcoma in a pelvic lesion who underwent the placement of a tissue expander (TE) before radiation therapy to prevent the adverse effects of radiotherapy. The simulation study showed that the TE drastically reduced volume of the intestine that was irradiated at all dose levels. All patients could receive the scheduled dose of radiotherapy without any acute and late complications such as diarrhea, melena, the dislodging of the TE, infection, or the formation of fistulae. In the 4-year (minimum) observation period, we did not observe intestinal complications in any of our patients. TE placement is considered to be a safe and effective method for preventing the adverse effects of radiotherapy in pediatric malignant pelvic tumors.
authors.affiliation: Departments of *Pediatric Surgery †Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors.forename: Shuichiro
authors.initials: S
authors.lastname: Uehara
authors.forename: Takaharu
authors.initials: T
authors.lastname: Oue
authors.forename: Kana
authors.initials: K
authors.lastname: Adachi
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Yoshioka
authors.forename: Kengo
authors.initials: K
authors.lastname: Nakahata
authors.forename: Takehisa
authors.initials: T
authors.lastname: Ueno
authors.forename: Hiroomi
authors.initials: H
authors.lastname: Okuyama
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000532:radiotherapy*; D002648:Child; D005260:Female; D006801:Humans; D007422:Intestines / Q000528:radiation effects*; D010386:Pelvic Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000517:prevention & control*; D011878:Radiotherapy / Q000009:adverse effects; D012512:Sarcoma, Ewing / Q000532:radiotherapy*; D015625:Tissue Expansion Devices