title: [PROGRESS OF MESENCHYMAL STEM CELL-DERIVED Exosomes IN TISSUE REPAIR].
abstract: OBJECTIVE
  To comprehensively analyze the recent advancements in the field of mesenchymal stem cells (MSCs) derived exosomes (MSCs-exosomes) in tissue repair.
  
  
  METHODS
  The literature about MSCs-exosomes in tissue repair was reviewed and analyzed.
  
  
  RESULTS
  Exosomes are biologically active microvesicles released from MSCs which are loaded with functional proteins, RNA, and microRNA. Exosomes can inhibit apoptosis, stimulate proliferation, alter cell phenotype in tissue repair of several diseases through cell-to-cell communication.
  
  
  CONCLUSIONS
  MSCs-exosomes is a novel source for the treatment of tissue repair. Further research of MSCs-exosomes biofunction, paracellular transport, and treatment mechanism will help the transform to clinical application.
authors.forename: Xiao
authors.initials: X
authors.lastname: Li
authors.forename: Lingying
authors.initials: L
authors.lastname: Liu
authors.forename: Jiake
authors.initials: J
authors.lastname: Chai
mesh_terms: D017209:Apoptosis; D002450:Cell Communication / Q000502:physiology*; D055354:Exosomes / Q000378:metabolism*; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000378:metabolism* / Q000502:physiology*; D035683:MicroRNAs; D012038:Regeneration; D014945:Wound Healing
chemical_list: D035683:MicroRNAs