title: Toxicity of Turmeric Extracts to the Termite Reticulitermes flavipes (Blattodea: Rhinotermitidae).
abstract: Turmeric is an important spice crop with documented human health benefits associated with chemicals called curcuminoids. In this study, the termite Reticulitermes flavipes (Kollar) was exposed to different solvent extracts of turmeric to investigate potential termiticidal properties. Treating termites with hexane extracts of purified lab-grade curcuminoids had no effect on termites. However, in continuous exposure assays, the LC(50) for hexane extracts of crude turmeric powder was 9.6 mg, or 1.0 mg starting material per square centimeter of filter paper substrate. These active components were soluble in a range of polar and apolar solvents, but only hexane could selectively fractionate active components away from the inactive curcuminoids. The active constituents of turmeric separated by thin layer chromatography (TLC) fluoresced in short-wave UV light but were not visible in long-wave UV light. By re-extracting TLC-separated bands in hexane and performing bioassays and gas chromatography-mass spectrometry, we demonstrated that termiticidal components of turmeric are extractable as a blend containing mainly ar-turmerone, turmerone, and curlone. This determination is consistent with findings of preceding work by other researchers that investigated insecticidal properties of turmeric in other pest insects.
authors.affiliation: Department of Entomology, Purdue University, West Lafayette, IN.
authors.forename: Kapil R
authors.initials: KR
authors.lastname: Raje
authors.affiliation: Department of Entomology, Purdue University, West Lafayette, IN.
authors.forename: Gabriel P
authors.initials: GP
authors.lastname: Hughes
authors.affiliation: Department of Entomology, Purdue University, West Lafayette, IN.
authors.forename: Ameya D
authors.initials: AD
authors.lastname: Gondhalekar
authors.affiliation: Department of Entomology, Purdue University, West Lafayette, IN.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Ginzel
authors.affiliation: Department of Entomology, Purdue University, West Lafayette, IN. mscharf@purdue.edu.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Scharf
mesh_terms: D000818:Animals; D030024:Curcuma; D007306:Insecticides; D020049:Isoptera; D007928:Lethal Dose 50; D010936:Plant Extracts
chemical_list: D007306:Insecticides; D010936:Plant Extracts; C012596:turmeric extract
keywords: curcumin; natural product; solvent extract; turmeric; turmerone