title: Keratitis by Paecilomyces lilacinus: A case report from Sub-Himalayan region.
abstract: Paecilomyces lilacinus is a filamentous fungus found in soil and air, which is a rare cause of ocular infection. The majority of case reports involving P. lilacinus among healthy hosts are of endophthalmitis and keratitis. We report a rare case of keratomycosis by P. lilacinus, in an immunocompetent, which responded well to treatment with ketoconazole. Some species belonging to the genus Paecilomyces such as P. lilacinus generally shows a poor response to conventional antifungal drugs. Therefore, correct identification of clinical isolates to the species level is mandatory for the appropriate treatment of the disease.
authors.affiliation: Department of Microbiology, IGMC, Shimla, Himachal Pradesh, India.
authors.forename: V
authors.initials: V
authors.lastname: Sharma
authors.forename: A
authors.initials: A
authors.lastname: Angrup
authors.forename: P
authors.initials: P
authors.lastname: Panwar
authors.forename: S
authors.initials: S
authors.lastname: Verma
authors.forename: D
authors.initials: D
authors.lastname: Singh
authors.forename: A
authors.initials: A
authors.lastname: Kanga
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage; D006801:Humans; D007194:India; D007634:Keratitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D007654:Ketoconazole / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010143:Paecilomyces / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D007654:Ketoconazole