title: Marine-Based Nutraceuticals: An Innovative Trend in the Food and Supplement Industries.
abstract: Recent trends in functional foods and supplements have demonstrated that bioactive molecules play a major therapeutic role in human disease. Nutritionists and biomedical and food scientists are working together to discover new bioactive molecules that have increased potency and therapeutic benefits. Marine life constitutes almost 80% of the world biota with thousands of bioactive compounds and secondary metabolites derived from marine invertebrates such as tunicates, sponges, molluscs, bryozoans, sea slugs and many other marine organisms. These bioactive molecules and secondary metabolites possess antibiotic, antiparasitic, antiviral, anti-inflammatory, antifibrotic and anticancer activities. They are also inhibitors or activators of critical enzymes and transcription factors, competitors of transporters and sequestrants that modulate various physiological pathways. The current review summaries the widely available marine-based nutraceuticals and recent research carried out for the purposes of isolation, identification and characterization of marine-derived bioactive compounds with various therapeutic potentials.
authors.affiliation: School of Medicine, the University of Queensland, Translational Research Institute, Kent Street, Woolloongabba, Brisbane 4102, Australia. hafiz.suleria@uqconnect.edu.au.|CSIRO Agriculture Flagship, 306 Carmody Road, St Lucia, QLD 4067, Australia. hafiz.suleria@uqconnect.edu.au.
authors.forename: Hafiz Ansar Rasul
authors.initials: HA
authors.lastname: Suleria
authors.affiliation: CSIRO Agriculture Flagship, 306 Carmody Road, St Lucia, QLD 4067, Australia. simone.osborne@csiro.au.
authors.forename: Simone
authors.initials: S
authors.lastname: Osborne
authors.affiliation: School of Medicine, the University of Queensland, Translational Research Institute, Kent Street, Woolloongabba, Brisbane 4102, Australia. p.masci@uq.edu.au.
authors.forename: Paul
authors.initials: P
authors.lastname: Masci
authors.affiliation: School of Medicine, the University of Queensland, Translational Research Institute, Kent Street, Woolloongabba, Brisbane 4102, Australia. g.gobe@uq.edu.au.
authors.forename: Glenda
authors.initials: G
authors.lastname: Gobe
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000378:metabolism*; D019587:Dietary Supplements; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D064210:Secondary Metabolism
keywords: bioactive molecules; functional foods; marine nutraceuticals; supplements and health perspectives