title: PBP2a substitutions linked to ceftaroline resistance in MRSA isolates from the UK.
authors.affiliation: Department of Medicine, University of Cambridge, Cambridge, UK eh439@cam.ac.uk.
authors.forename: Ewan M
authors.initials: EM
authors.lastname: Harrison
authors.affiliation: Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
authors.forename: Xiaoliang
authors.initials: X
authors.lastname: Ba
authors.affiliation: Department of Medicine, University of Cambridge, Cambridge, UK.
authors.forename: Beth
authors.initials: B
authors.lastname: Blane
authors.affiliation: Clinical Microbiology and Public Health Laboratory, Public Health England, Cambridge, UK.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Ellington
authors.affiliation: Royal Veterinary College, Hawkshead Campus, University of London, London, UK.
authors.forename: Anette
authors.initials: A
authors.lastname: Loeffler
authors.affiliation: Antimicrobial Resistance and Healthcare Associated Infections Reference Unit, Public Health England, London, UK.
authors.forename: Robert L R
authors.initials: RL
authors.lastname: Hill
authors.affiliation: Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Holmes
authors.affiliation: Department of Medicine, University of Cambridge, Cambridge, UK Clinical Microbiology and Public Health Laboratory, Public Health England, Cambridge, UK Wellcome Trust Sanger Institute, Hinxton, UK.
authors.forename: Sharon J
authors.initials: SJ
authors.lastname: Peacock
mesh_terms: D019943:Amino Acid Substitution; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics*; D002511:Cephalosporins / Q000494:pharmacology*; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D046915:Penicillin-Binding Proteins / Q000235:genetics*; D013203:Staphylococcal Infections / Q000382:microbiology; D006113:United Kingdom; D018440:beta-Lactam Resistance; D000097583:Ceftaroline
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002511:Cephalosporins; D046915:Penicillin-Binding Proteins; D000097583:Ceftaroline; C487789:mecA protein, Staphylococcus aureus