title: The impact of obsessive dimension on symptoms and functioning in schizophrenia.
abstract: Obsessive Compulsive Symptoms (OCS) and Disorder (OCD) occur frequently in patients with schizophrenia. Nevertheless the impact of OCS/OCD on clinical characteristics and outcome of schizophrenia remains controversial. The aim of the present study is to examine the effect of obsessive-compulsive dimension on symptom expression and functioning in schizophrenia. Sixty patients affected by schizophrenia completed the SCID-IV, the Positive and Negative Syndrome Scale, the Yale-Brown Obsessive-Compulsive Scale, the Social and Occupational Functioning Assessment Scale and the Strauss and Carpenter Level of Functioning Rating Scale. Obsessive-compulsive dimension was associated neither with positive or disorganization symptoms nor with negative symptoms. By contrast, it adversely affected levels of functioning, with a major impact exerted by compulsions rather than obsessions. Obsessive-compulsive dimension appears to be independent from negative and positive symptoms of schizophrenia and independently decreases social functioning.
authors.affiliation: Department of Mental Health, Local Health Service, Parma, Italy. Electronic address: mtonna@ausl.pr.it.
authors.forename: Matteo
authors.initials: M
authors.lastname: Tonna
authors.affiliation: Department of Neuroscience, Psychiatric Unit, University of Parma, Italy.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Ottoni
authors.affiliation: Department of Mental Health, Local Health Service, Parma, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Affaticati
authors.affiliation: Department of Mental Health, Local Health Service, Parma, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Ferrari
authors.affiliation: Department of Mental Health, Local Health Service, Parma, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Monici
authors.affiliation: Department of Neuroscience, Psychiatric Unit, University of Parma, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Ossola
authors.affiliation: Department of Neuroscience, Psychiatric Unit, University of Parma, Italy; Department of Mental Health, Local Health Service, Parma, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: De Panfilis
authors.affiliation: Department of Neuroscience, Psychiatric Unit, University of Parma, Italy; Department of Mental Health, Local Health Service, Parma, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Marchesi
mesh_terms: D000328:Adult; D003192:Compulsive Behavior / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009770:Obsessive Behavior / Q000209:etiology / Q000503:physiopathology*; D012559:Schizophrenia / Q000150:complications / Q000503:physiopathology*; D066107:Social Skills
keywords: Functioning; Negative symptoms; Obsessive–compulsive symptoms; Positive symptoms; Schizophrenia