title: Male hormonal contraception: looking back and moving forward.
abstract: Despite numerous contraceptive options available to women, approximately half of all pregnancies in the United States and worldwide are unplanned. Women and men support the development of reversible male contraception strategies, but none have been brought to market. Herein we review the physiologic basis for male hormonal contraception, the history of male hormonal contraception development, currents agents in development as well as the potential risks and benefits of male hormonal contraception for men.
authors.affiliation: Department of Medicine and Center for Research in Reproduction and Contraception, University of Washington, Seattle, WA, USA.
authors.forename: M Y
authors.initials: MY
authors.lastname: Roth
authors.affiliation: Department of Medicine and Center for Research in Reproduction and Contraception, University of Washington, Seattle, WA, USA.
authors.forename: S T
authors.initials: ST
authors.lastname: Page
authors.affiliation: Department of Medicine and Center for Research in Reproduction and Contraception, University of Washington, Seattle, WA, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Bremner
mesh_terms: D003267:Contraception / Q000379:methods*; D003272:Contraceptive Agents, Male / Q000494:pharmacology*; D006801:Humans; D008297:Male; D009653:Norprogesterones / Q000494:pharmacology; D013739:Testosterone / Q000494:pharmacology; D045165:Testosterone Congeners / Q000494:pharmacology
chemical_list: D003272:Contraceptive Agents, Male; D009653:Norprogesterones; D045165:Testosterone Congeners; D013739:Testosterone; C029167:ST 1435
keywords: contraception; spermatogenesis; testosterone