title: Prenatal Magnetic Resonance Imaging of Atypical Partial Rhombencephalosynapsis with Involvement of the Anterior Vermis: Two Case Reports.
abstract: Rhombencephalosynapsis is a hindbrain malformation characterized by complete or partial absence of the cerebellar vermis, with varying degrees of midline continuity of cerebellar hemispheres, dentate nuclei, and in some patients of the superior cerebellar peduncles. Partial rhombencephalosynapsis usually consists of a segmental deficiency of posterior vermis. Although prenatal diagnosis of rhombencephalosynapsis is feasible by ultrasound and magnetic resonance imaging both, partial rhombencephalosynapsis might be difficult to detect, especially at an early gestational age. We report two fetal cases of atypical partial rhombencephalosynapsis, with deficiency of anterior vermis, detected by prenatal magnetic resonance imaging at 21st and 23rd week of gestation, respectively.
authors.affiliation: Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Via Castelvetro, Milan, Italy.
authors.forename: Giana
authors.initials: G
authors.lastname: Izzo
authors.affiliation: Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Via Castelvetro, Milan, Italy.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Conte
authors.affiliation: Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Via Castelvetro, Milan, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Cesaretti
authors.affiliation: Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Via Castelvetro, Milan, Italy.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Parazzini
authors.affiliation: Department of Pathology, San Paolo Hospital, Via Antonio di Rudini, Milan, Italy.
authors.forename: Gaetano
authors.initials: G
authors.lastname: Bulfamante
authors.affiliation: Radiology and Neuroradiology Department, Children's Hospital V. Buzzi, Via Castelvetro, Milan, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Righini
mesh_terms: D000328:Adult; D002526:Cerebellar Diseases / Q000175:diagnosis* / Q000473:pathology; D065814:Cerebellar Vermis / Q000473:pathology*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009421:Nervous System Malformations / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications; D011296:Prenatal Diagnosis