title: Chemical profile, antiproliferative and antioxidant activities of rhizome oil of Zingiber anamalayanum from Western Ghats in India.
abstract: Volatile oil from fresh rhizomes of Zingiber anamalayanum was isolated by hydrodistillation and characterised by GC-FID and GC-MS. Twenty-one out of 24 constituents comprising 99.47% of the oil were identified. Major components in Z. anamalayanum rhizome oil were δ-2-carene (52.83%), camphene (9.83%), endo-fenchol (9.42%), iso-dihydrocarveol (6.44%) and cis-p-mentha-2,8-dien-1-ol (5.19%). Monoterpene hydrocarbons in the rhizome oil were 65.81%, followed by oxygenated monoterpenes (23.78%) and sesquiterpene hydrocarbons (9.87%). Physical parameters of rhizome oil were [Formula: see text] 1.4031, [Formula: see text] - 16.097(o) (c = 1, CHCl3) and [Formula: see text] 0.9202. Z. anamalayanum rhizome oil showed significant anti-Dalton's Lymphoma Ascitic activity.
authors.affiliation: a Phytochemistry and Phytopharmacology Division , Jawaharlal Nehru Tropical Botanic Garden and Research Institute , Thiruvananthapuram , India.|b Plant Genetic Resource Division , Jawaharlal Nehru Tropical Botanic Garden and Research Institute , Thiruvananthapuram , India.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Salim
authors.affiliation: c Department of Botany , University of Calicut , Malappuram , India.
authors.forename: T K Ahmedul
authors.initials: TK
authors.lastname: Kabeer
authors.affiliation: a Phytochemistry and Phytopharmacology Division , Jawaharlal Nehru Tropical Botanic Garden and Research Institute , Thiruvananthapuram , India.
authors.forename: S Ajikumaran
authors.initials: SA
authors.lastname: Nair
authors.affiliation: b Plant Genetic Resource Division , Jawaharlal Nehru Tropical Botanic Garden and Research Institute , Thiruvananthapuram , India.
authors.forename: Mathew
authors.initials: M
authors.lastname: Dan
authors.affiliation: c Department of Botany , University of Calicut , Malappuram , India.
authors.forename: M
authors.initials: M
authors.lastname: Sabu
authors.affiliation: a Phytochemistry and Phytopharmacology Division , Jawaharlal Nehru Tropical Botanic Garden and Research Institute , Thiruvananthapuram , India.
authors.forename: Sabulal
authors.initials: S
authors.lastname: Baby
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D000081008:Bicyclic Monoterpenes; D001892:Camphanes; D049109:Cell Proliferation / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007194:India; D008223:Lymphoma / Q000473:pathology; D039821:Monoterpenes / Q000032:analysis; D009636:Norbornanes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D027343:Rhizome / Q000737:chemistry*; D012717:Sesquiterpenes / Q000032:analysis; D013729:Terpenes / Q000032:analysis; D030521:Zingiberaceae
chemical_list: D000975:Antioxidants; D000081008:Bicyclic Monoterpenes; D001892:Camphanes; D039821:Monoterpenes; D009636:Norbornanes; D009822:Oils, Volatile; D012717:Sesquiterpenes; D013729:Terpenes; C027328:fenchol; C113988:2-carene; C019286:camphene; C534305:2-methyl-5-(1-methylethenyl)cyclohexanol
keywords: Zingiber anamalayanum; camphene; cytotoxic activity; essential oil; gas chromatography; δ-2-carene