title: Optimizing calcium selective fluorimetric nanospheres.
abstract: Recently it was shown that optical nanosensors based on alternating polymers e.g. poly(maleic anhydride-alt-1-octadecene) were characterized by a linear dependence of emission intensity on logarithm of concentration over a few of orders of magnitude range. In this work we focus on the material used to prepare calcium selective nanosensors. It is shown that alternating polymer nanosensors offer competitive performance in the absence of calcium ionophore, due to interaction of the nanospheres building blocks with analyte ions. The emission increase corresponds to increase of calcium ions contents in the sample within the range from 10(-4) to 10(-1) M. Further improvement in sensitivity (from 10(-6) to 10(-1) M) and selectivity can be achieved by incorporating calcium ionophore in the nanospheres. The optimal results were obtained for core-shell nanospheres, where the core was prepared from poly(styrene-co-maleic anhydride) and the outer layer from poly(maleic anhydride-alt-1-octadecene). Thus obtained chemosensors were showing linear dependence of emission on logarithm of calcium ions concentration within the range from 10(-7) to 10(-1) M.
authors.affiliation: Department of Chemistry, Warsaw University, Pasteura 1, 02-093 Warsaw, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Kisiel
authors.affiliation: Department of Chemistry, Warsaw University, Pasteura 1, 02-093 Warsaw, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kłucińska
authors.affiliation: Department of Chemistry, Warsaw University, Pasteura 1, 02-093 Warsaw, Poland.
authors.forename: Marianna
authors.initials: M
authors.lastname: Gniadek
authors.affiliation: Department of Chemistry, Warsaw University, Pasteura 1, 02-093 Warsaw, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Maksymiuk
authors.affiliation: Department of Chemistry, Warsaw University, Pasteura 1, 02-093 Warsaw, Poland. Electronic address: agatam@chem.uw.edu.pl.
authors.forename: Agata
authors.initials: A
authors.lastname: Michalska
keywords: Alternating polymer; Calcium ions; Fluorimetric chemosensors; Ion-exchanger; Nanospheres; Synthesis