title: Cationic Porphyrin-Anionic Surfactant Mixtures for the Promotion of Self-Organized 1:4 Ion Pairs in Water with Strong Aggregation Properties.
abstract: We performed a systematic study on the spectroscopic and aggregation properties of stoichiometric mixtures (1:4) of the tetracationic meso-tetrakis(4-N-methylpyridinium)porphyrin (H2 TMPyP) and three sodium alkylsulfate surfactants (tetradecyl, hexadecyl, and octadecylsulfate) in an aqueous solution. The objective was to build a supramolecular aggregate, which would favor the internalization of tetracationic porphyrins in cells without chemical modification of the structure of the porphyrin. We show that stoichiometric H2 TMPyP/alkylsulfate (1:4) mixtures lead to the formation of large hollow spherical aggregates (60-160 nm). The TEM images show that the membrane of these aggregates are composed of smaller aggregates, which are probably rod-like micelles. These rod-like micelles have a hydrophobic core composed of the alkyl chains of the alkylsulfate surfactant, whereas the charged surface corresponds to the tetracationic porphyrins.
authors.affiliation: Laboratoire de Chimie de Coordination CNRS, UPR 8241, 205 route de Narbonne, BP 44099, 31077, Toulouse cedex 4, France.|Université de Toulouse, Université Paul Sabatier UPS, INPT, Toulouse, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Pradines
authors.affiliation: Laboratoire de Chimie de Coordination CNRS, UPR 8241, 205 route de Narbonne, BP 44099, 31077, Toulouse cedex 4, France.|Université de Toulouse, Université Paul Sabatier UPS, INPT, Toulouse, France.
authors.forename: Christian
authors.initials: C
authors.lastname: Bijani
authors.affiliation: Laboratoire de Chimie de Coordination CNRS, UPR 8241, 205 route de Narbonne, BP 44099, 31077, Toulouse cedex 4, France.|Université de Toulouse, Université Paul Sabatier UPS, INPT, Toulouse, France.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Stigliani
authors.affiliation: Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique, UMR 5623 CNRS, 118 route de Narbonne, 31062, Toulouse cedex 9, France.|Université de Toulouse, Université Paul Sabatier UPS, INPT, Toulouse, France.
authors.forename: Muriel
authors.initials: M
authors.lastname: Blanzat
authors.affiliation: Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique, UMR 5623 CNRS, 118 route de Narbonne, 31062, Toulouse cedex 9, France.|Université de Toulouse, Université Paul Sabatier UPS, INPT, Toulouse, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Rico-Lattes
authors.affiliation: Laboratoire de Chimie de Coordination CNRS, UPR 8241, 205 route de Narbonne, BP 44099, 31077, Toulouse cedex 4, France.|Université de Toulouse, Université Paul Sabatier UPS, INPT, Toulouse, France.
authors.forename: Geneviève
authors.initials: G
authors.lastname: Pratviel
mesh_terms: D000838:Anions; D002412:Cations; D046529:Microscopy, Electron, Transmission; D011166:Porphyrins / Q000737:chemistry*; D066244:Proton Magnetic Resonance Spectroscopy; D013501:Surface-Active Agents / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D000838:Anions; D002412:Cations; D011166:Porphyrins; D013501:Surface-Active Agents; D014867:Water
keywords: aggregation; cationic porphyrins; ion pairs; spherical aggregates; surfactants