title: Autoimmune lymphoproliferative syndrome caused by a homozygous FasL mutation that disrupts FasL assembly.
authors.affiliation: Division of Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors.forename: Ali
authors.initials: A
authors.lastname: Sobh
authors.affiliation: Division of Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors.forename: Elena
authors.initials: E
authors.lastname: Crestani
authors.affiliation: Division of Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors.forename: Brittney
authors.initials: B
authors.lastname: Cangemi
authors.affiliation: Division of Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Kane
authors.affiliation: Division of Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors.forename: Janet
authors.initials: J
authors.lastname: Chou
authors.affiliation: Division of Hematology-Oncology, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
authors.forename: Sung-Yun
authors.initials: SY
authors.lastname: Pai
authors.affiliation: Division of Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors.forename: Luigi D
authors.initials: LD
authors.lastname: Notarangelo
authors.affiliation: Allergy and Clinical Immunology Unit, Department of Pediatrics, Al-Sabah Hospital, Kuwait City, Kuwait; Department of Pediatrics, Kuwait University, Kuwait City, Kuwait.
authors.forename: Waleed
authors.initials: W
authors.lastname: Al-Herz
authors.affiliation: Division of Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors.forename: Raif S
authors.initials: RS
authors.lastname: Geha
authors.affiliation: Division of Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass. Electronic address: michel.massaad@childrens.harvard.edu.
authors.forename: Michel J
authors.initials: MJ
authors.lastname: Massaad
mesh_terms: D000818:Animals; D056735:Autoimmune Lymphoproliferative Syndrome / Q000235:genetics*; D016466:CHO Cells; D003412:Cricetulus; D053222:Fas Ligand Protein / Q000235:genetics* / Q000378:metabolism; D005260:Female; D006720:Homozygote; D006801:Humans; D007223:Infant; D007963:Leukocytes, Mononuclear / Q000378:metabolism; D008297:Male; D009154:Mutation
chemical_list: C505661:FASLG protein, human; D053222:Fas Ligand Protein