title: Case Presentation of Concomitant and Contiguous Adenomatoid Odontogenic Tumor and Focal Cemento-Ossifying Dysplasia.
abstract: A 24 year-old male was presented for the diagnosis of an asymptomatic bony expansion in relation to the right maxillary canine and first premolar. The unilocular radiolucent lesion with central foci of calcification had caused divergence of canine and first premolar roots without any resorption. This case report details a diagnosis of two distinct disease processes of different cellular origin namely, focal cemento-ossifying dysplasia and adenomatoid odontogenic tumor in a previously unreported concomitant and contiguous relationship. The diagnosis was determined by a combination of clinical, radiographic, histopathological and surgical evidence. This case highlights two points, first the need to examine all mixed radiolucent-radiopaque lesions with advanced imaging techniques to assess the number and extent of the lesions prior to treatment planning. Second a likely role of periodontal ligament as the tissue source for odontogenic epithelial cells and mesenchymal stem cells required for the development of odontogenic tumors and cemento-osseous dysplasias.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Shahed University, Tehran, Iran.
authors.forename: Gita
authors.initials: G
authors.lastname: Rezvani
authors.affiliation: OMFP Center, Belgaum, India.
authors.forename: Mandana
authors.initials: M
authors.lastname: Donoghue
authors.affiliation: University Professor emeritus, Charité, Department of Oral Medicine, Dental Radiology and Oral Surgery (Prof A.M. Schmidt- Westhausen) CC3, Assmannshauser str. 4-6, 14197, Berlin, Germany.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Reichart
authors.affiliation: Department of Conservative Dentistry, Faculty of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Neda
authors.initials: N
authors.lastname: Pazuhi
keywords: Adenomatoid odontogenic tumor; cemento-osseous dysplasia; cone beam-CT; extrafollicular; focal cemento-osseous dysplasia; odontogenic tumor; periodontal ligament