title: A randomised controlled trial of bilateral dual transversus abdominis plane blockade for laparoscopic appendicectomy.
abstract: We investigated the effects of pre-operative ultrasound-guided bilateral dual transversus abdominis plane blocks on pain when sitting up and pain at rest after laparoscopic appendicectomy. We allocated 28 participants to injection with 60 ml ropivacaine 0.375% and 28 participants to 60 ml isotonic saline. The median (IQR [range]) cumulative pain scores during the first 12 postoperative hours were less after ropivacaine than saline (maximum 120): on sitting, 34 (19-46 [0-59]) vs 50 (30-59 [0-97]), respectively, p = 0.009; and at rest, 25 (10-33 [0-49]) vs 31 (24-43 [0-72]), respectively, p = 0.035. There were no differences in morphine consumption, nausea, vomiting, time in recovery or time to walk.
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Copenhagen University Hospital - Roskilde, Roskilde, Denmark.
authors.forename: K
authors.initials: K
authors.lastname: Tanggaard
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: K
authors.initials: K
authors.lastname: Jensen
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: K
authors.initials: K
authors.lastname: Lenz
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Vazin
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: J
authors.initials: J
authors.lastname: Binzer
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: V O
authors.initials: VO
authors.lastname: Lindberg-Larsen
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Niegsch
authors.affiliation: Department of Anaesthesia, Aarhus University Hospital, Aarhus, Denmark.
authors.forename: T F
authors.initials: TF
authors.lastname: Bendtsen
authors.affiliation: Digestive Disease Centre, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: L N
authors.initials: LN
authors.lastname: Jorgensen
authors.affiliation: Department of Anaesthesia and Intensive Care Medicine, Copenhagen University Hospital - Roskilde, Roskilde, Denmark.
authors.forename: J
authors.initials: J
authors.lastname: Børglum
mesh_terms: D000009:Abdominal Muscles / Q000294:innervation*; D000328:Adult; D000577:Amides / Q000494:pharmacology; D001062:Appendectomy / Q000379:methods*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage; D009407:Nerve Block / Q000379:methods*; D000077212:Ropivacaine
chemical_list: D000577:Amides; D009020:Morphine; D000077212:Ropivacaine