title: Conformational promiscuity in triazolamers derived from quaternary amino acids mimics peptide behaviour.
abstract: 1,4-Substituted triazole oligomers made from quaternary amino acid derivatives present a conformational behaviour with similarities to that of natural peptides. Twisted strand and zig-zag type conformations have both been obtained in the crystal state. In a solution signs of weakly ordered structures have been detected depending on the substituents and the solvents used.
authors.affiliation: Department of Biological Chemistry and Molecular Modelling, Institute of Advanced Chemistry of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain. jordi.sola@iqac.csic.es ignacio.alfonso@iqac.csic.es.
authors.forename: Jordi
authors.initials: J
authors.lastname: Solà
authors.forename: Michael
authors.initials: M
authors.lastname: Bolte
authors.forename: Ignacio
authors.initials: I
authors.lastname: Alfonso
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry*; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary; D012997:Solvents; D014230:Triazoles / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D010455:Peptides; D012997:Solvents; D014230:Triazoles