title: Nitrogen-doped carbon nanospheres derived from cocoon silk as metal-free electrocatalyst for glucose sensing.
abstract: Nitrogen-doped carbon materials have attracted tremendous attention because of their high activity in electrocatalysis. In the present work, cocoon silk -- a biomass material is used to prepare porous carbon fibers due to its abundant nitrogen content. The as-prepared carbon microfibers have been activated and disintegrated into carbon nanospheres (CNS) with a diameter of 20--60 nm by a simple nitric acid refluxing process. Considering their excellent electrocatalytic activity towards the reduction of oxygen, the CNS modified electrodes are further applied in the construction of glucose amperometric biosensor using glucose oxidase as a model. The proposed biosensor exhibits fast response, high sensitivity, good stability and selectivity for glucose detection with a wide linear range from 79.7 to 2038.9 μM, and a detection limit of 39.1 μM. The performance is comparable to leading literature results indicating a great potential for electrochemical sensing application.
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China.
authors.forename: Tongtong
authors.initials: T
authors.lastname: Li
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China.
authors.forename: Yahang
authors.initials: Y
authors.lastname: Li
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China.
authors.forename: Chunyu
authors.initials: C
authors.lastname: Wang
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China; Lab of Solid State Microstructures, Nanjing University, Nanjing 210093, China.
authors.forename: Zhi-Da
authors.initials: ZD
authors.lastname: Gao
authors.affiliation: College of Sciences, Northeastern University, Shenyang 110004, China. Electronic address: yysong@mail.neu.edu.cn.
authors.forename: Yan-Yan
authors.initials: YY
authors.lastname: Song
mesh_terms: D000818:Animals; D001234:Aspergillus niger / Q000201:enzymology; D015374:Biosensing Techniques / Q000379:methods*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D004563:Electrochemistry; D004566:Electrodes; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D005949:Glucose Oxidase / Q000737:chemistry / Q000378:metabolism; D054118:Nanospheres / Q000737:chemistry*; D017942:Nitric Acid / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D016062:Porosity; D011679:Pupa / Q000737:chemistry; D047011:Silk / Q000737:chemistry*; D012995:Solubility; D014867:Water / Q000737:chemistry
chemical_list: D047011:Silk; D014867:Water; D017942:Nitric Acid; D002244:Carbon; D005949:Glucose Oxidase; D005947:Glucose; D009584:Nitrogen; D010100:Oxygen
keywords: Biosensor; Carbon nanospheres; Carbonization; Glucose; Oxygen reduction