title: "A Sledgehammer Breaks Glass but Forges Steel": Bacteria Adhesion Shapes Gut Immunity.
abstract: Gut bacteria are known to affect immune cell development, but most intestinal lymphocytes have no direct contact with luminal bacteria. Two studies by Atarashi et al. and Sano et al. shed light on how bacterial adhesion can cue intestinal epithelial cells to direct differentiation of gut T cells.
authors.affiliation: Laboratory of Mucosal Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA.
authors.forename: Virginia A
authors.initials: VA
authors.lastname: Pedicord
authors.affiliation: Laboratory of Mucosal Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA. Electronic address: mucida@rockefeller.edu.
authors.forename: Daniel
authors.initials: D
authors.lastname: Mucida
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion; D044082:Citrobacter rodentium / Q000502:physiology*; D004756:Enterobacteriaceae Infections / Q000276:immunology*; D004927:Escherichia coli Infections / Q000276:immunology*; D019453:Escherichia coli O157 / Q000502:physiology*; D000069196:Gastrointestinal Microbiome; D006801:Humans; D007378:Interleukins / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000276:immunology*; D007422:Intestines / Q000276:immunology*; D018123:Receptors, Interleukin / Q000378:metabolism*; D000685:Serum Amyloid A Protein / Q000378:metabolism*; D058504:Th17 Cells / Q000276:immunology*
chemical_list: D007378:Interleukins; D018123:Receptors, Interleukin; D000685:Serum Amyloid A Protein