title: Association of Systemic Anaplastic Large Cell Lymphoma and Active Toxoplasmosis in a Child.
abstract: BACKGROUND
  Anaplastic large cell lymphoma is a subset of non-Hodgkin lymphoma and an unusual disease in children.
  
  
  METHODS
  Herein we have reported a 7- year- old girl with a large necrotic skin ulcer on the chest caused by systemic form of anaplastic large-cell lymphoma and simultaneous active toxoplasmosis diagnosed by PCR on lymph node specimen. There were few reports showing a role for toxoplasma infection to cause some malignancies such as lymphoma in adults.
  
  
  CONCLUSIONS
  Based to our knowledge, this has been the first report of simultaneous systemic anaplastic large cell lymphoma and active toxoplasmosis, documented by positive PCR on tissue biopsy in a child. This case report has suggested more attention to the accompanying Toxoplasma gondii infection as a probable cause of some types of lymphomas.
authors.affiliation: Department of Paediatrics, Ali Asghar Children Hospital, Iran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Shirin
authors.initials: S
authors.lastname: Sayyahfar
authors.affiliation: Paediatric Infection Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
authors.forename: Abdollah
authors.initials: A
authors.lastname: Karimi
authors.affiliation: Department of Pathology, Imam Hosein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
authors.forename: Atoosa
authors.initials: A
authors.lastname: Gharib
authors.affiliation: Paediatric Infection Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Fahimzad
keywords: Anaplastic Large-Cell Lymphoma; Non-Hodgkin Lymphoma; Toxoplasmosis