title: Determination of four paraben-type preservatives and three benzophenone-type ultraviolet light filters in seafoods by LC-QqLIT-MS/MS.
abstract: For the first time, an efficient and sensitive analytical method based on liquid chromatography-quadrupole linear ion trap-tandem mass spectrometry (LC-QqLIT-MS/MS) was developed for the simultaneous determination of four paraben-type preservatives and three benzophenone-type ultraviolet light filters in both plant (Sargassum fusiforme, porphyra, kelp) and animal (hairtail, yellow croaker, shrimp) seafood. The samples were extracted in methanol by pressurized liquid extraction (PLE), and the extracts were then cleaned up by mixed-mode cationic exchange (MCX) solid-phase extraction cartridges. Both isotope-labeled internal standards and matrix-matched calibration standards were used to alleviate and correct for the matrix effects, and the limits of quantification (LOQs) were 10.0μg kg(-1) for all target compounds. The average recoveries were in the range of 80.6-107.8% at three spiked concentration levels (10, 50 and 100μgkg(-1)) with relative standard deviations (RSDs) below 8.5%. The results suggest that very limited contamination of these seven emerging contaminants, mainly associated with PCPs, occurred in these common seafoods.
authors.affiliation: Wenzhou Entry-Exit Inspection and Quarantine Bureau of P.R.C, Wenzhou 325027, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Han
authors.affiliation: Wenzhou Entry-Exit Inspection and Quarantine Bureau of P.R.C, Wenzhou 325027, China.
authors.forename: Biqi
authors.initials: B
authors.lastname: Xia
authors.affiliation: Wenzhou Entry-Exit Inspection and Quarantine Bureau of P.R.C, Wenzhou 325027, China.
authors.forename: Xiangzhun
authors.initials: X
authors.lastname: Chen
authors.affiliation: Food Inspection Center of Shenzhen Entry-Exit Inspection and Quarantine, Shenzhen 518045, China.
authors.forename: Jincan
authors.initials: J
authors.lastname: Shen
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Miao
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China. Electronic address: shenyan@wzu.edu.cn.
authors.forename: Yan
authors.initials: Y
authors.lastname: Shen
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D005506:Food Contamination / Q000032:analysis; D005520:Food Preservatives / Q000032:analysis* / Q000302:isolation & purification; D033541:Palaemonidae / Q000737:chemistry; D010226:Parabens / Q000032:analysis* / Q000302:isolation & purification; D010473:Perciformes; D017747:Seafood / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods; D053719:Tandem Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D014466:Ultraviolet Rays
chemical_list: D005520:Food Preservatives; D010226:Parabens
keywords: Benzophenone-type ultraviolet light filters; LC-QqLIT-MS/MS; Paraben-type preservatives; Seafood