title: [Current prevention and treatment strategies for osteoporosis. Fracture-oriented, effective, low side effects and inexpensive].
abstract: Osteoporosis is still an underdiagnosed and insufficiently therapied widespread disease in Germany. Of the estimated 7 million osteoporosis patients only 1.5 million receive a guideline conform diagnosis and even less receive appropriate treatment. Some 90 % of patients are provided with analgesics but only 10 % receive an effective therapy, although efficacious, well-tested and affordable medications are available. In addition, approximately one half of the patients terminate treatment after only 1 year although according to the results of recent studies the duration of therapy should be at least 3-5 years. In view of the increasing average life expectancy, a consistent management for prevention of fractures associated with osteoporosis is always most important for society, even if only for reasons of costs. Achievement of this target depends on four circumstances: clarification of the origin of osteoporosis and fractures (bone consciousness), prophylaxis of bone loss and fractures (primary prevention), consistent guideline conform diagnostics and therapy (secondary and tertiary prevention) and cooperation of all disciplines in medicine (bone is everybody's business). This article describes the current state of diagnostics (bone density measurement with dual X-ray absorptiometry, FRAX®), prophylaxis of fractures (screening program) and therapy (use of economic and effective medications with low side effects). Novel medications are already undergoing clinical testing and a "healing" of bone reduction with restoration of the normal bone structure is to be expected.
authors.affiliation: Osteoporosezentrum am Dom, Kaufingerstr. 15, 80331, München, Deutschland. reiner.bartl@osteologie-online.de.
authors.forename: R
authors.initials: R
authors.lastname: Bartl
authors.affiliation: Osteoporosezentrum am Dom, Kaufingerstr. 15, 80331, München, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Bartl
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D050071:Bone Density Conservation Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D058866:Osteoporotic Fractures / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D050071:Bone Density Conservation Agents
keywords: Absorptiometry, dual energy X-ray; Drug therapy, osteoporosis; Osteoporotic fractures; Prevention and control, fractures; Risk assessment