title: [Rhino-orbito-cerebral mucormycosis: two case reports in the light of the literature].
abstract: Rhino-orbito-cerebral mucormycosis is an acute onset and often fatal disease. Risk factors include uncontrolled diabetes mellitus, hematological malignancies, and long-term corticosteroid use. Early diagnosis and treatment are important. The underlying causes should be treated, surgical debridement should be performed and appropriate antifungal drugs should be given. In this article, we report two diabetic ketoacidosis patients who developed rhino-orbito-cerebral mucormycosis and were treated with surgical debridement and amphotericin B therapy.
authors.affiliation: Department of Otolaryngology, Medical Faculty of Çanakkale Onsekiz Mart University, 17020 Kepez, Çanakkale, Turkey. medinekara@gmail.com.
authors.forename: Medine
authors.initials: M
authors.lastname: Kara
authors.forename: Halil
authors.initials: H
authors.lastname: Erdoğan
authors.forename: Tolgahan
authors.initials: T
authors.lastname: Toroslu
authors.forename: Alper
authors.initials: A
authors.lastname: Akçalı
authors.forename: Müşerref
authors.initials: M
authors.lastname: Tatman Okun
authors.forename: Mustafa
authors.initials: M
authors.lastname: Reşorlu
authors.forename: Fevzi Sefa
authors.initials: FS
authors.lastname: Dereköy
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001927:Brain Diseases / Q000382:microbiology*; D020314:Central Nervous System Fungal Infections / Q000175:diagnosis; D003646:Debridement / Q000379:methods; D016883:Diabetic Ketoacidosis / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000175:diagnosis*; D009668:Nose Diseases / Q000382:microbiology*; D009916:Orbital Diseases / Q000382:microbiology*; D012307:Risk Factors
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B