title: Achiral Dye/Surfactant Heteroaggregates for Chiral Sensing of Phosphocholines.
abstract: An investigation, based on absorption and circular dichroism spectroscopy, was carried out on assemblies formed in water upon the interaction of heteroaggregates, composed of dyes (Congo Red or Evans Blue) and cetyltrimethylammonium bromide (CTAB), with four enantiopure phopshocholines (DMPC, DPPC, DOPC, and POPC) characterized by the same polar head and different hydrophobic tails. The results show that the nature of the lipid as well as the concentration ratios influence sensitively the absorption and chiroptical properties of the supramolecular structure. Intriguingly, the transfer of chirality from the lipid to the assembly may be triggered or not, depending on the nature of the lipid hydrophobic chain. These findings confirm the fundamental role of hydrophobic interactions in the transcription of chirality from molecules to complex architectures.
authors.affiliation: CNR-IMC-Sezione Meccanismi di Reazione c/o Dipartimento di Chimica, Sapienza, Università di Roma, Rome, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Ceccacci
authors.affiliation: Dipartimento di Chimica, Sapienza, Università di Roma, Rome, Italy.
authors.forename: Anita
authors.initials: A
authors.lastname: Scipioni
authors.affiliation: Dipartimento di Chimica, Università dell'Aquila, Coppito, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Altieri
authors.affiliation: Dipartimento di Chimica, Università dell'Aquila, Coppito, Italy.
authors.forename: Luisa
authors.initials: L
authors.lastname: Giansanti
authors.affiliation: CNR-IMC Istituto di Metodologie Chimiche, Monterotondo, Italy.
authors.forename: Giovanna
authors.initials: G
authors.lastname: Mancini
keywords: chiral architecture; chiral information; chiral lipid; circular dichroism; dye; heteroaggregate