title: The stiff elastographic change of submandibular glands rapidly improves after the introduction of glucocorticoid treatment in patients with IgG4-related dacryoadenitis and sialoadenitis.
abstract: In three patients with immunoglobulin G4-related dacryoadenitis and sialoadenitis (IgG4-DS), we assessed the changes in the hardness of affected submandibular glands by the real-time tissue elastography at baseline and 2 weeks after the initiation of treatment with oral glucocorticoids. Elastography revealed "blue" meaning to be a hard tissue matched the hypoechoic areas inside the enlarged submandibular glands before treatment. The stiff elastographic changes rapidly improved after 2 weeks. This may relate with the reversibility of salivary function by glucocorticoid treatment in patients with IgG4-DS.
authors.affiliation: a Department of Public Health .|b Department of Immunology and Rheumatology , and.
authors.forename: Shin-Ya
authors.initials: SY
authors.lastname: Kawashiri
authors.affiliation: b Department of Immunology and Rheumatology , and.
authors.forename: Ayako
authors.initials: A
authors.lastname: Nishino
authors.affiliation: b Department of Immunology and Rheumatology , and.
authors.forename: Hideki
authors.initials: H
authors.lastname: Nakamura
authors.affiliation: c Department of Health Sciences , Nagasaki University Graduate School of Biomedical Sciences , Nagasaki , Japan.
authors.forename: Tomoki
authors.initials: T
authors.lastname: Origuchi
authors.affiliation: b Department of Immunology and Rheumatology , and.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Aoyagi
authors.affiliation: a Department of Public Health .
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawakami
mesh_terms: D003607:Dacryocystitis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000276:immunology; D054459:Elasticity Imaging Techniques; D005260:Female; D005938:Glucocorticoids / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008875:Middle Aged; D012793:Sialadenitis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000276:immunology; D013363:Submandibular Gland / Q000000981:diagnostic imaging* / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D007074:Immunoglobulin G
keywords: Elastography; Glucocorticoid; IgG4-related dacryoadenitis and sialoadenitis