title: Laparoscopic Indocyanine Green Sentinel Lymph Node Mapping in Pregnant Cervical Cancer Patients.
abstract: We present cases of 2 pregnant patients with early-stage cervical cancer who have undergone indocyanine green (ICG) sentinel lymph node (SLN) mapping followed by laparoscopic SLN biopsy, pelvic lymphadenectomy, and cervical conization. Eight milliliters of ICG were injected in the 4 quadrants of the cervix after having obtained an adequate pneumoperitoneum and having inspected the abdominal cavity. SLNs were identified in both hemipelvises in both patients. In the final pathologic analysis, both SLNs and non-SLNs were negative for metastatic disease. No adverse events from ICG injection were recorded. ICG SLN mapping seems to be feasible in pregnant cervical cancer patients.
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Berne and University of Berne, Berne, Switzerland. Electronic address: andrea.papadia@insel.ch.
authors.forename: Andrea
authors.initials: A
authors.lastname: Papadia
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Berne and University of Berne, Berne, Switzerland.
authors.forename: Stefan
authors.initials: S
authors.lastname: Mohr
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Berne and University of Berne, Berne, Switzerland.
authors.forename: Sara
authors.initials: S
authors.lastname: Imboden
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Berne and University of Berne, Berne, Switzerland.
authors.forename: Susanne
authors.initials: S
authors.lastname: Lanz
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Berne and University of Berne, Berne, Switzerland.
authors.forename: Daniele
authors.initials: D
authors.lastname: Bolla
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital of Berne and University of Berne, Berne, Switzerland.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Mueller
mesh_terms: D000328:Adult; D004396:Coloring Agents; D019092:Conization; D005260:Female; D006801:Humans; D007208:Indocyanine Green; D010535:Laparoscopy; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000601:surgery; D011256:Pregnancy Outcome; D021701:Sentinel Lymph Node Biopsy; D019265:Spectroscopy, Near-Infrared; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green
keywords: Cervical cancer; Indocyanine green; Laparoscopy; Near infrared fluorescence imaging; Pregnancy; Sentinel lymph node mapping