title: Hematological Alterations in Common Carp (Cyprinus carpio L.) Exposed to Herbicides: Pendimethalin and Ethofumesate Tested Separately and in Mixture.
abstract: Herbicides are used in large amounts in agriculture and the evaluation of their toxic effects is of major concern to environmental safety. The aim of the present study was to investigate common carp hematological alterations caused by herbicide exposure. Fish were treated with pendimethalin and ethofumesate tested separately and in mixture administered to aquarium water. Peripheral blood of treated fish was collected after 1, 3 and 7 days of exposure and compared to control. The total number of erythrocytes (RBC), total number of leukocytes (WBC), hematocrit value (Hct), total hemoglobin concentration (Hb), mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC) and leukograms were determined at once. The results indicate that herbicide exposure caused different changes in the hematological profile of the fish. In the case of exposure to individual herbicides, short-term fluctuations of various hematological indices were noted. Moreover, a significant increase in RBC and Hct after a short period of exposure (1-3 days) in fish exposed simultaneously to both tested herbicides was observed. Exposure to herbicides affected the leukocyte profile after 3 and 7 days of duration. Fluctuations of hematological parameters are a typical change in fish exposed to pesticides.
authors.forename: Bartosz
authors.initials: B
authors.lastname: Bojarski
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Ludwikowska
authors.forename: Anna
authors.initials: A
authors.lastname: Kurek
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Pawlak
authors.forename: Barbara
authors.initials: B
authors.lastname: Tombarkiewicz
authors.forename: Hanna
authors.initials: H
authors.lastname: Lutnicka
mesh_terms: D000814:Aniline Compounds / Q000633:toxicity*; D000818:Animals; D001572:Benzofurans / Q000633:toxicity*; D002347:Carps; D006403:Hematologic Tests; D006540:Herbicides / Q000633:toxicity*; D008698:Mesylates / Q000633:toxicity*
chemical_list: D000814:Aniline Compounds; D001572:Benzofurans; D006540:Herbicides; D008698:Mesylates; C412911:ethofumesate; C030856:pendimethalin