title: The effect of serum and follicular fluid amyloid-associated protein levels on in vitro fertilization outcome in patients with polycystic ovary syndrome.
abstract: OBJECTIVE
  In this study, we aimed to investigate serum and follicular fluid amyloid A protein levels in non-obese non-hyperandrogenic patients with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization (IVF) and IVF outcome.
  
  
  METHODS
  A total of 81 patients undergoing IVF treatment, 41 patients diagnosed as PCOS according to the Rotterdam criteria (group I) and 40 patients with the etiology of male factor infertility (group II), were included in the study. On the day of oocyte pickup, serum and follicular fluid samples were collected from all patients.
  
  
  RESULTS
  Serum E2 level on the day of hCG (2849.93 ± 541.54 vs. 2494.28 ± 712.98) and total number of retrieved oocytes (13.73 ± 3.57 vs. 10.53 ± 4.07) were significantly higher in group I when compared to group II (p < 0.05). However, number of mature oocytes, fertilization rate, and clinical pregnancy rate did not differ (p > 0.05). No significant difference was found between two groups regarding the serum and follicular fluid amyloid A protein levels on the day of oocyte retrieval (p > 0.05).
authors.affiliation: Department of Reproductive Endocrinology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, ZTB, Hamaonu, Altindag, 06500, Ankara, Turkey. drhakantimur@gmail.com.
authors.forename: Hakan
authors.initials: H
authors.lastname: Timur
authors.affiliation: Department of Reproductive Endocrinology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, ZTB, Hamaonu, Altindag, 06500, Ankara, Turkey.
authors.forename: Nafiye
authors.initials: N
authors.lastname: Yimaz
authors.affiliation: Department of Reproductive Endocrinology, Etlik Zubeyde Hanim Women's Health Education and Research Hospital, Ankara, Turkey.
authors.forename: Inci
authors.initials: I
authors.lastname: Kahyaoglu
authors.affiliation: Department of Obstetrics and Gynecology, Konya Education and Research Hospital, Konya, Turkey.
authors.forename: Hasan Ali
authors.initials: HA
authors.lastname: Inal
authors.affiliation: Department of Reproductive Endocrinology, Dr. Zekai Tahir Burak Women's Health Education and Research Hospital, ZTB, Hamaonu, Altindag, 06500, Ankara, Turkey.
authors.forename: Salim
authors.initials: S
authors.lastname: Erkaya
mesh_terms: D000328:Adult; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D015571:Follicular Fluid / Q000378:metabolism*; D006801:Humans; D007247:Infertility, Female / Q000097:blood; D016015:Logistic Models; D008297:Male; D054315:Oocyte Retrieval; D011085:Polycystic Ovary Syndrome / Q000097:blood*; D011247:Pregnancy; D018873:Pregnancy Rate; D000685:Serum Amyloid A Protein / Q000032:analysis*; D016896:Treatment Outcome
chemical_list: D000685:Serum Amyloid A Protein; D004958:Estradiol
keywords: Adipokine; Amyloid A; In vitro fertilization; Polycystic ovary syndrome