title: miTRATA: a web-based tool for microRNA Truncation and Tailing Analysis.
abstract: CONCLUSIONS
  We describe miTRATA, the first web-based tool for microRNA Truncation and Tailing Analysis--the analysis of 3' modifications of microRNAs including the loss or gain of nucleotides relative to the canonical sequence. miTRATA is implemented in Python (version 3) and employs parallel processing modules to enhance its scalability when analyzing multiple small RNA (sRNA) sequencing datasets. It utilizes miRBase, currently version 21, as a source of known microRNAs for analysis. miTRATA notifies user(s) via email to download as well as visualize the results online. miTRATA's strengths lie in (i) its biologist-focused web interface, (ii) improved scalability via parallel processing and (iii) its uniqueness as a webtool to perform microRNA truncation and tailing analysis.
  
  
  METHODS
  miTRATA is developed in Python and PHP. It is available as a web-based application from https://wasabi.dbi.udel.edu/∼apps/ta/.
  
  
  BACKGROUND
  meyers@dbi.udel.edu
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Center for Bioinformatics and Computational Biology and Delaware Biotechnology Institute and.
authors.forename: Parth
authors.initials: P
authors.lastname: Patel
authors.affiliation: Delaware Biotechnology Institute and.
authors.forename: S Deepthi
authors.initials: SD
authors.lastname: Ramachandruni
authors.affiliation: Center for Bioinformatics and Computational Biology and Delaware Biotechnology Institute and.
authors.forename: Atul
authors.initials: A
authors.lastname: Kakrana
authors.affiliation: Department of Plant and Soil Sciences, University of Delaware, Newark, DE 19711, USA.
authors.forename: Mayumi
authors.initials: M
authors.lastname: Nakano
authors.affiliation: Delaware Biotechnology Institute and Department of Plant and Soil Sciences, University of Delaware, Newark, DE 19711, USA.
authors.forename: Blake C
authors.initials: BC
authors.lastname: Meyers
mesh_terms: D000465:Algorithms; D000818:Animals; D019295:Computational Biology / Q000379:methods*; D020407:Internet; D035683:MicroRNAs / Q000235:genetics*; D010944:Plants / Q000235:genetics; D017423:Sequence Analysis, RNA / Q000379:methods*; D012984:Software
chemical_list: D035683:MicroRNAs