title: Relationships between the resting-state network and the P3: Evidence from a scalp EEG study.
abstract: The P3 is an important event-related potential that can be used to identify neural activity related to the cognitive processes of the human brain. However, the relationships, especially the functional correlations, between resting-state brain activity and the P3 have not been well established. In this study, we investigated the relationships between P3 properties (i.e., amplitude and latency) and resting-state brain networks. The results indicated that P3 amplitude was significantly correlated with resting-state network topology, and in general, larger P3 amplitudes could be evoked when the resting-state brain network was more efficient. However, no significant relationships were found for the corresponding P3 latency. Additionally, the long-range connections between the prefrontal/frontal and parietal/occipital brain regions, which represent the synchronous activity of these areas, were functionally related to the P3 parameters, especially P3 amplitude. The findings of the current study may help us better understand inter-subject variation in the P3, which may be instructive for clinical diagnosis, cognitive neuroscience studies, and potential subject selection for brain-computer interface applications.
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Fali
authors.initials: F
authors.lastname: Li
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.|Center for Information in BioMedicine, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Tiejun
authors.initials: T
authors.lastname: Liu
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: He
authors.initials: H
authors.lastname: Li
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Diankun
authors.initials: D
authors.lastname: Gong
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: College of Bio-information, ChongQing University of Posts and Telecommunications, Chongqing, 400065, China.
authors.forename: Yin
authors.initials: Y
authors.lastname: Tian
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.|Center for Information in BioMedicine, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Daqing
authors.initials: D
authors.lastname: Guo
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.|Center for Information in BioMedicine, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Dezhong
authors.initials: D
authors.lastname: Yao
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, 610054, China.|Center for Information in BioMedicine, University of Electronic Science and Technology of China, Chengdu, 610054, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Xu
mesh_terms: D000328:Adult; D062207:Brain-Computer Interfaces; D004569:Electroencephalography; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005625:Frontal Lobe / Q000502:physiology; D006801:Humans; D008297:Male; D009415:Nerve Net / Q000502:physiology*; D009778:Occipital Lobe / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology; D012146:Rest / Q000502:physiology*; D012535:Scalp / Q000502:physiology; D013647:Task Performance and Analysis