title: Esthesioneuroblastoma With Poor Outcome Despite Extensive Treatment.
abstract: Esthesioneuroblastoma is a rare malignant tumor of neuroectodermal origin. It usually presents with nonspecific symptoms, such as nasal obstruction, epistaxis, and pain, but has an aggressive course if the treatment is delayed. The authors report a case of esthesioneuroblastoma in a 47-year-old woman, treated with extensive surgical resection, radiotherapy, and chemotherapy. Despite intensive treatment, the patient developed a local recurrence with systemic metastasis and succumbed 4 months later.
authors.affiliation: *Department of Ophthalmology, Medical Faculty, Ondokuz Mayis University, Samsun †Department of Ophthalmology ‡Department of Ear Nose and Throat §Department of Pathology, Medical Faculty, Ankara University, Ankara, Turkey.
authors.forename: Leyla
authors.initials: L
authors.lastname: Niyaz
authors.forename: Kaan
authors.initials: K
authors.lastname: Gunduz
authors.forename: Cem
authors.initials: C
authors.lastname: Meco
authors.forename: Duygu
authors.initials: D
authors.lastname: Kankaya
mesh_terms: D001932:Brain Neoplasms / Q000556:secondary; D017024:Chemotherapy, Adjuvant; D018304:Esthesioneuroblastoma, Olfactory / Q000556:secondary / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis / Q000473:pathology; D008875:Middle Aged; D009296:Nasal Cavity / Q000601:surgery*; D015508:Nasal Obstruction / Q000175:diagnosis; D020360:Neoadjuvant Therapy / Q000379:methods; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009669:Nose Neoplasms / Q000601:surgery*; D009918:Orbital Neoplasms / Q000556:secondary; D018714:Radiotherapy, Adjuvant