title: Interaction between the Kansas City Cardiomyopathy Questionnaire and the Pocock's clinical score in predicting heart failure outcomes.
abstract: OBJECTIVE
  Heart failure (HF) is a complex syndrome. Its appropriate management should combine several health measurements. We assessed the relationship between the Kansas City Cardiomyopathy Questionnaire (KCCQ) and the Pocock's clinical score.
  
  
  METHODS
  We conducted a prospective registry of HF outpatients. The main outcome was occurrence of death or hospitalization during a 6-month follow-up. A multivariate logistic regression was performed, including the KCCQ overall summary score, the Pocock's clinical score and their interaction in the model.
  
  
  RESULTS
  From January 2008 to December 2010, 143 patients were involved. Mean age of patients was 68 years, and 74% were men. KCCQ's overall summary score and Pocock's clinical score were inversely correlated (r = -0.24, p = 0.026). A total of 61 (42.7%) events occurred. There was a high proportion of events (77.8%) in patients with a Pocock's clinical score > 50%, whatever the KCCQ score value. When the KCCQ score was ≤ 50 %, there was a low increase in risk as the Pocock's clinical score increased (OR 2.0 [0.6; 6.6]). However, when the KCCQ score was between 50 and 75 or ≥ 75 %, there was a high increase in risk as the Pocock's clinical score increased (OR 6.9 [1.2; 38.9] and OR 7.4 [0.8; 69.7], respectively).
  
  
  CONCLUSIONS
  Patients with a high Pocock's clinical score are at a high risk of death or hospitalization. For patients with a low Pocock's clinical score, the KCCQ score can identify those at risk of these events.
authors.affiliation: The Pôle de recherche Epidémiologie et Biostatistique, Institut de Recherche Expérimentale et Clinique (IREC-EPID), Université catholique de Louvain, Clos Chapelle-aux-Champs 30, Box B1.30.13, 1200, Brussels, Belgium. kiswendsida.sawadogo@uclouvain.be.
authors.forename: Kiswendsida
authors.initials: K
authors.lastname: Sawadogo
authors.affiliation: The Pôle de recherche Epidémiologie et Biostatistique, Institut de Recherche Expérimentale et Clinique (IREC-EPID), Université catholique de Louvain, Clos Chapelle-aux-Champs 30, Box B1.30.13, 1200, Brussels, Belgium.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Ambroise
authors.affiliation: The Brussels Heart Centre (BHC), Clinique Saint Jean, Boulevard du Jardin Botanique 32, 1000, Brussels, Belgium.
authors.forename: Steven
authors.initials: S
authors.lastname: Vercauteren
authors.affiliation: The Brussels Heart Centre (BHC), Clinique Saint Jean, Boulevard du Jardin Botanique 32, 1000, Brussels, Belgium.
authors.forename: Marc
authors.initials: M
authors.lastname: Castadot
authors.affiliation: Société Scientifique de Médecine Générale (SSMG), Rue de Suisse 8, 1060, Brussels, Belgium.
authors.forename: Michel
authors.initials: M
authors.lastname: Vanhalewyn
authors.affiliation: The Brussels Heart Centre (BHC), Clinique Saint Jean, Boulevard du Jardin Botanique 32, 1000, Brussels, Belgium.
authors.forename: Jacques
authors.initials: J
authors.lastname: Col
authors.affiliation: The Pôle de recherche Epidémiologie et Biostatistique, Institut de Recherche Expérimentale et Clinique (IREC-EPID), Université catholique de Louvain, Clos Chapelle-aux-Champs 30, Box B1.30.13, 1200, Brussels, Belgium.
authors.forename: Annie
authors.initials: A
authors.lastname: Robert
mesh_terms: D000368:Aged; D009202:Cardiomyopathies / Q000188:drug therapy* / Q000401:mortality*; D005260:Female; D006304:Health Status; D006333:Heart Failure / Q000188:drug therapy* / Q000401:mortality*; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D007615:Kansas; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
keywords: Heart failure; Kansas City Cardiomyopathy Questionnaire; Quality of life