title: An automated real-time integration and interoperability framework for bioinformatics.
abstract: BACKGROUND
  In recent years data integration has become an everyday undertaking for life sciences researchers. Aggregating and processing data from disparate sources, whether through specific developed software or via manual processes, is a common task for scientists. However, the scope and usability of the majority of current integration tools fail to deal with the fast growing and highly dynamic nature of biomedical data.
  
  
  RESULTS
  In this work we introduce a reactive and event-driven framework that simplifies real-time data integration and interoperability. This platform facilitates otherwise difficult tasks, such as connecting heterogeneous services, indexing, linking and transferring data from distinct resources, or subscribing to notifications regarding the timeliness of dynamic data. For developers, the framework automates the deployment of integrative and interoperable bioinformatics applications, using atomic data storage for content change detection, and enabling agent-based intelligent extract, transform and load tasks.
  
  
  CONCLUSIONS
  This work bridges the gap between the growing number of services, accessing specific data sources or algorithms, and the growing number of users, performing simple integration tasks on a recurring basis, through a streamlined workspace available to researchers and developers alike.
authors.affiliation: DETI/IEETA, Universidade de Aveiro, Campus Universitario de Santiago, Aveiro, 3810-193, Portugal. pedrolopes@ua.pt.
authors.forename: Pedro
authors.initials: P
authors.lastname: Lopes
authors.affiliation: DETI/IEETA, Universidade de Aveiro, Campus Universitario de Santiago, Aveiro, 3810-193, Portugal. jlo@ua.pt.
authors.forename: José Luís
authors.initials: JL
authors.lastname: Oliveira
mesh_terms: D001331:Automation; D000067917:Cloud Computing; D019295:Computational Biology; D006801:Humans; D012984:Software