title: Renal tumor in developing countries: 142 cases from a single institution at Shanghai, China.
abstract: BACKGROUND
  The clinical management of children with renal tumors including Wilms' tumor, clear cell sarcoma, rhabdoid tumor and other renal tumors in our center was designed according to the National Wilms' Tumor Study Group protocols.
  
  
  METHODS
  A total of 142 consecutive patients who had been diagnosed as having renal tumors at Shanghai Children's Medical Center were reviewed retrospectively in the period of December 1998 and September 2012. Diagnosis and treatment were decided by a multidisciplinary team including oncologists, surgeons, pathologists and sub-specialized radiologists.
  
  
  RESULTS
  The median age of the patients at the time of diagnosis was 27 months. The tumor stages of the patients were as follows: stage I 24.6%, stage II 23.2%, stage III 32.3%, stage IV 14.1%, and stage V 5.6%. Favorable histology was diagnosed in 80.3%, anaplasia in 4.2%, clear cell sarcoma in 9.8%, rhabdoid tumor in 4.9%, and other renal tumors in 0.7% of the patients. The event-free and overall 5-year survival rates were 80% and 83%, respectively. Tumor relapse and progress was seen in 25 patients (17.6%). The median relapse time was 6 months (range: 2-37 months). Seven relapsing patients were retreated and four of them got second complete remission (three in stage II, one in stage I).
  
  
  CONCLUSIONS
  A multi-disciplinary team work model is feasible in developing countries, and the renal tumors protocols basically from developed countries are safe in developing countries.
authors.affiliation: , Shanghai, China.|Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Ci
authors.initials: C
authors.lastname: Pan
authors.affiliation: , Shanghai, China.|Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Jiao-Yang
authors.initials: JY
authors.lastname: Cai
authors.affiliation: , Shanghai, China.|Department of Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Min
authors.initials: M
authors.lastname: Xu
authors.affiliation: , Shanghai, China.|Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Qi-Dong
authors.initials: QD
authors.lastname: Ye
authors.affiliation: , Shanghai, China.|Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhou
authors.affiliation: , Shanghai, China.|Department of Pathology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Min-Zhi
authors.initials: MZ
authors.lastname: Yin
authors.affiliation: , Shanghai, China.|Department of Radiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Yu-Min
authors.initials: YM
authors.lastname: Zhong
authors.affiliation: , Shanghai, China.|Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Chen
authors.affiliation: , Shanghai, China.|Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
authors.forename: Shu-Hong
authors.initials: SH
authors.lastname: Shen
authors.affiliation: , Shanghai, China. tangjingyan@scmc.com.cn.|Department of Hematology/Oncology, Shanghai Children's Medical Center, Shanghai Jiao Tong University, School of Medicine, Shanghai, China. tangjingyan@scmc.com.cn.
authors.forename: Jing-Yan
authors.initials: JY
authors.lastname: Tang
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003131:Combined Modality Therapy; D003906:Developing Countries; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D008297:Male; D009367:Neoplasm Staging; D010348:Patient Care Team; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome
keywords: China; developing country; multi-disciplinary team; renal tumors