title: Hybrid Intercalated Duct Lesion of the Parotid: Diagnostic Challenges of a Recently Described Entity with Fine Needle Aspiration Findings.
abstract: Intercalated duct lesions (IDL) of the salivary glands are recently described, and encompass both hyperplasia and benign neoplasms that remain incompletely understood. IDLs have been linked to various benign and low-grade malignant salivary gland neoplasms. We herein present a case of a 77 year old woman with an IDL of the parotid composed of both a hyperplastic and an adenomatous component and report, for the first time, the fine needle aspiration findings of such a lesion. This case illustrates the morphologic spectrum of an IDL, as well as challenges in rendering an accurate cytological and histologic diagnosis. The potential diagnostic pitfalls presented by the hybrid pattern of this lesion are also discussed.
authors.affiliation: Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
authors.forename: Yingting
authors.initials: Y
authors.lastname: Mok
authors.affiliation: Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
authors.forename: Yin Huei
authors.initials: YH
authors.lastname: Pang
authors.affiliation: Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
authors.forename: Ming
authors.initials: M
authors.lastname: Teh
authors.affiliation: Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore. fredrikpetersson@live.se.
authors.forename: Fredrik
authors.initials: F
authors.lastname: Petersson
mesh_terms: D000236:Adenoma / Q000473:pathology*; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D044963:Biopsy, Fine-Needle; D002277:Carcinoma / Q000473:pathology / Q000628:therapy; D002291:Carcinoma, Papillary; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology*; D007150:Immunohistochemistry; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D016609:Neoplasms, Second Primary / Q000473:pathology*; D010307:Parotid Neoplasms / Q000473:pathology*; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000473:pathology / Q000628:therapy
chemical_list: D014408:Biomarkers, Tumor; D007457:Iodine Radioisotopes
keywords: Fine needle aspiration cytology; Intercalated duct adenoma; Intercalated duct hyperplasia; Intercalated duct lesion; Parotid; Salivary gland