title: NYPD Cancer Incidence Rates 1995-2014 Encompassing the Entire World Trade Center Cohort.
abstract: OBJECTIVE
  The aim of this study was to compare cancer incidence rates (CIRs), between preexposure (1995-2000) and postexposure (2002-2014) periods in the entire New York City Police Department cohort exposed to the 2001 World Trade Center (WTC) disaster.
  
  
  METHODS
  CIR derived from active duty officer records, including postexposure data on retired officers.
  
  
  RESULTS
  We observed 870 cancer cases in 859 officers (1995-2014), including 193 active duty cases pre-WTC and 677 cases (484 active duty, 193 retired) post-WTC. Overall, median CIR increased 1.44-fold compared with pre-WTC, with brain cancer increasing 3.27-fold, and kidney cancer increasing similarly. Thyroid cancer and non-Hodgkin's lymphoma increased 2.29 and 1.68-fold, respectively.
  
  
  CONCLUSIONS
  Findings should be interpreted cautiously, given the small number of cancers at specific sites, and possibility of confounders. However, apparent increases in cancers overall, and in highlighted sites, remain of concern, underscoring the need for continued monitoring of this cohort.
authors.affiliation: Office of the Supervising Chief Surgeon and Medical Division, Personnel Bureau, New York City Police Department, New York, NY, Department of Medicine, Division of Hematology, Bronx, NY (Dr Kleinman); Division of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY (Drs Christos and Gerber); Medical Division, New York City Police Department, New York, NY (Dr Reilly); Office of the Supervising Chief Surgeon, New York City Police Department, New York, NY (Lt Moran); Department of Medicine, Division of Cardiology, Department of Radiology, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University Medical Center and New York-Presbyterian Hospital, New York, NY (Dr Einstein); Department of Medicine, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY (Dr Neugut).
authors.forename: Eli J
authors.initials: EJ
authors.lastname: Kleinman
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Christos
authors.forename: Linda M
authors.initials: LM
authors.lastname: Gerber
authors.forename: John P
authors.initials: JP
authors.lastname: Reilly
authors.forename: William F
authors.initials: WF
authors.lastname: Moran
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Einstein
authors.forename: Alfred I
authors.initials: AI
authors.lastname: Neugut
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology / Q000209:etiology*; D009519:New York City; D009784:Occupational Diseases / Q000453:epidemiology / Q000209:etiology*; D016273:Occupational Exposure / Q000009:adverse effects*; D016495:Police / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D047851:September 11 Terrorist Attacks