title: Surgical treatment of bronchial asthma by resection of the laryngeal nerve.
abstract: BACKGROUND
  Management of asthma in chronically affected patients is a serious health problem. Our aim was to show that surgical treatment of chronic bronchial asthma by unilateral resection of the internal branch of the superior laryngeal nerve (ib-SLN) is an adequateand lasting remedial response.
  
  
  METHODS
  In a retrospective study, 41 (26 male and 15 female) patients with bronchial chronic asthma were treated surgically during the period between 2005 and 2013. It consisted of a unilateral resection of the ib-SLN under optical zoom, on patients placed in supinator position. 35 patients (24 male and 11 female) who were un-operated were included as a control.
  
  
  RESULTS
  In all patients, medication was reduced progressively. When the results were compared with the control group, it was seen that in 26% of the patients, both forced expiratory volume (FEV) and peak expiratory flow (PEF) increased significantly (p <05) and only modestly in 53.6% of patients (FEV, p <05 and PEF, p <05). In the remaining 20% of patients, these parameters remained however unchanged. Overall, in 80% of patients unilateral resection of the ib-SLN gave satisfactory results because it shortened the intervals and duration of asthmatic attacks, rendering thereby a reduction in medication.
  
  
  CONCLUSIONS
  This minimal-invasive method helped prevent/cure asphyxias in chronic bronchial asthma without affecting cough reflex,respiratory control and phonation and it helped patients avoid severe crisis. This approach is of interest for patients with severe and/or uncontrolled bronchial asthma in settings with limited access to drug treatment.
authors.affiliation: Department of Plastic, Reconstructive Microsurgery and Regenerative Medicine, Avicenna Tajik State Medical University, Dushanbe, Tajikistan.
authors.forename: Ubaidullo
authors.initials: U
authors.lastname: Kurbon
authors.affiliation: Department of Plastic, Reconstructive Microsurgery and Regenerative Medicine, Avicenna Tajik State Medical University, Dushanbe, Tajikistan.
authors.forename: Hamza
authors.initials: H
authors.lastname: Dodariyon
authors.affiliation: Department of Plastic, Reconstructive Microsurgery and Regenerative Medicine, Avicenna Tajik State Medical University, Dushanbe, Tajikistan.
authors.forename: Abdumalik
authors.initials: A
authors.lastname: Davlatov
authors.affiliation: Department of Plastic, Reconstructive Microsurgery and Regenerative Medicine, Avicenna Tajik State Medical University, Dushanbe, Tajikistan.
authors.forename: Sitora
authors.initials: S
authors.lastname: Janobilova
authors.affiliation: Sorbonne Cité Paris, INSERM U965, University Paris 7, Lariboisiere Hospital, 41 bd de la Chapelle, 75010, Paris, France.
authors.forename: Amu
authors.initials: A
authors.lastname: Therwath
authors.affiliation: Department of Plastic, Reconstructive Microsurgery and Regenerative Medicine, Avicenna Tajik State Medical University, Dushanbe, Tajikistan. massoud.mirshahi@inserm.fr.|Sorbonne Cité Paris, INSERM U965, University Paris 7, Lariboisiere Hospital, 41 bd de la Chapelle, 75010, Paris, France. massoud.mirshahi@inserm.fr.
authors.forename: Massoud
authors.initials: M
authors.lastname: Mirshahi
mesh_terms: D000328:Adult; D000368:Aged; D001249:Asthma / Q000503:physiopathology / Q000601:surgery*; D002908:Chronic Disease; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D007823:Laryngeal Nerves / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods*; D010366:Peak Expiratory Flow Rate; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult