title: Autoimmune-Like Hepatitis: A "Hepatitic" Manifestation of Chronic Graft Versus Host Disease in Post-Stem Cell Transplant.
abstract: A 59-year-old female received a matched related donor stem cell transplant for chronic myelogenous leukemia. After being successfully treated with prednisone for chronic graft versus host disease that initially started 50 days posttransplant, she developed hepatic dysfunction during the steroid taper on day 531, as evidenced by jaundice, elevated liver enzymes, and increased bilirubin. Liver biopsy showed histology suggestive of autoimmune-like hepatitis, which is a rare manifestation of chronic "hepatitic" graft versus host disease.
authors.affiliation: University of Saskatchewan, Saskatoon, Saskatchewan, Canada nmb509@mail.usask.ca.
authors.forename: Nick M
authors.initials: NM
authors.lastname: Baniak
authors.affiliation: University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
authors.forename: Rani
authors.initials: R
authors.lastname: Kanthan
mesh_terms: D017809:Fatal Outcome; D005260:Female; D006086:Graft vs Host Disease / Q000473:pathology*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D019693:Hepatitis, Autoimmune / Q000209:etiology / Q000473:pathology*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy*; D008875:Middle Aged
keywords: autoimmune hepatitis; autoimmune-like hepatitis; chronic graft versus host disease; stem cell transplant