title: Two New Cytoarchitectonic Areas on the Human Mid-Fusiform Gyrus.
abstract: Areas of the fusiform gyrus (FG) within human ventral temporal cortex (VTC) process high-level visual information associated with faces, limbs, words, and places. Since classical cytoarchitectonic maps do not adequately reflect the functional and structural heterogeneity of the VTC, we studied the cytoarchitectonic segregation in a region, which is rostral to the recently identified cytoarchitectonic areas FG1 and FG2. Using an observer-independent and statistically testable parcellation method, we identify 2 new areas, FG3 and FG4, in 10 human postmortem brains on the mid-FG. The mid-fusiform sulcus reliably identifies the cytoarchitectonic transition between FG3 and FG4. We registered these cytoarchitectonic areas to the common reference space of the single-subject Montreal Neurological Institute (MNI) template and generated probability maps, which reflect the intersubject variability of both areas. Future studies can relate in vivo neuroimaging data with these microscopically defined cortical areas to functional parcellations. We discuss these results in the context of both large-scale functional maps and fine-scale functional clusters that have been identified within the human VTC. We propose that our observer-independent cytoarchitectonic parcellation of the FG better explains the functional heterogeneity of the FG compared with the homogeneity of classic cytoarchitectonic maps.
authors.affiliation: Institute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
authors.forename: Simon
authors.initials: S
authors.lastname: Lorenz
authors.affiliation: Department of Psychology.
authors.forename: Kevin S
authors.initials: KS
authors.lastname: Weiner
authors.affiliation: Institute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.|Department of Diagnostic and Interventional Radiology, University Düsseldorf, Medical Faculty, Düsseldorf, Germany.
authors.forename: Julian
authors.initials: J
authors.lastname: Caspers
authors.affiliation: Institute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
authors.forename: Hartmut
authors.initials: H
authors.lastname: Mohlberg
authors.affiliation: Institute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
authors.forename: Axel
authors.initials: A
authors.lastname: Schleicher
authors.affiliation: Institute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Bludau
authors.affiliation: Institute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.|Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Düsseldorf, Germany.
authors.forename: Simon B
authors.initials: SB
authors.lastname: Eickhoff
authors.affiliation: Department of Psychology.|Neuroscience Institute, Stanford University, Stanford, CA, USA.
authors.forename: Kalanit
authors.initials: K
authors.lastname: Grill-Spector
authors.affiliation: Institute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.|Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany.|JARA-BRAIN, Jülich-Aachen Research Alliance, Jülich, Germany.
authors.forename: Karl
authors.initials: K
authors.lastname: Zilles
authors.affiliation: Institute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.|C. & O. Vogt Institute for Brain Research, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.|JARA-BRAIN, Jülich-Aachen Research Alliance, Jülich, Germany.
authors.forename: Katrin
authors.initials: K
authors.lastname: Amunts
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013702:Temporal Lobe / Q000033:anatomy & histology*
keywords: cytoarchitecture; fusiform gyrus; mid-fusiform sulcus (MFS); probabilistic mapping; ventral temporal cortex (VTC)