title: Pleuroparenchymal fibroelastosis in association with carcinomas.
abstract: PPFE is a rare disease characterized by upper lobe pleural fibrosis and parenchymal fibroelastosis. Its aetiology is considered idiopathic, although possible causative factors have been described. An association of PPFE with solid tumours is unknown and has not been considered previously. We identified six patients with PPFE, four of them with a coexisting malignancy. The case series suggests that PPFE might be an implication of varying factors rather than being an exclusively idiopathic condition.
authors.affiliation: Department of Pneumology and Respiratory Critical Care Medicine, Center for Interstitial and Rare Lung Diseases, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.|Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Eva
authors.initials: E
authors.lastname: Baroke
authors.affiliation: Department of Diagnostic and Interventional Radiology, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.|Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Claus Peter
authors.initials: CP
authors.lastname: Heussel
authors.affiliation: Translational Lung Research Center Heidelberg, Heidelberg, Germany.|Institute of Pathology, University of Heidelberg, Heidelberg, Germany.
authors.forename: Arne
authors.initials: A
authors.lastname: Warth
authors.affiliation: Department of Diagnostic and Interventional Radiology, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.|Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Monika
authors.initials: M
authors.lastname: Eichinger
authors.affiliation: Department of Pneumology and Respiratory Critical Care Medicine, Center for Interstitial and Rare Lung Diseases, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.|Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Ute
authors.initials: U
authors.lastname: Oltmanns
authors.affiliation: Department of Pneumology and Respiratory Critical Care Medicine, Center for Interstitial and Rare Lung Diseases, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.|Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Karin
authors.initials: K
authors.lastname: Palmowski
authors.affiliation: Department of Pneumology and Respiratory Critical Care Medicine, Center for Interstitial and Rare Lung Diseases, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.|Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Felix J F
authors.initials: FJ
authors.lastname: Herth
authors.affiliation: Department of Pneumology and Respiratory Critical Care Medicine, Center for Interstitial and Rare Lung Diseases, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.|Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Kreuter
mesh_terms: D000368:Aged; D001706:Biopsy; D001943:Breast Neoplasms / Q000150:complications / Q000473:pathology; D018278:Carcinoma, Neuroendocrine / Q000150:complications / Q000473:pathology; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000150:complications / Q000473:pathology; D063868:Patient Outcome Assessment; D010995:Pleural Diseases / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D011658:Pulmonary Fibrosis / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D012129:Respiratory Function Tests / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: cancer; interstitial lung disease; lung fibrosis; pleuroparenchymal fibroelastosis