title: Clinical Clues to Predict the Presence of Parafoveal Scotoma on Humphrey 10-2 Visual Field Using a Humphrey 24-2 Visual Field.
abstract: OBJECTIVE
  To investigate characteristics related to the presence of parafoveal scotoma on Humphrey 10-2 visual field (VF) in early glaucoma patients.
  
  
  METHODS
  Prospective, cross-sectional study.
  
  
  METHODS
  participants: Ninety-one eyes from 91 patients with glaucomatous optic neuropathy were prospectively tested with a 10-2 VF test.
  
  
  METHODS
  Glaucoma patients were classified into eyes with or without parafoveal scotoma on 10-2 VF based on pattern deviation plot. The central 10 degree region of Humphrey 24-2 VF test comprised 12 points and any abnormal VF points depressed <5%, <2%, <1%, or <0.5% from the normal database on pattern deviation plot were analyzed. Various factors related to the presence of parafoveal scotoma on 10-2 VF were analyzed.
  
  
  METHODS
  Abnormal 24-2 VF points, macular ganglion cell-inner plexiform layer thickness.
  
  
  RESULTS
  The presence of abnormal 24-2 VF points <0.5% was significantly different between eyes with and without parafoveal scotoma on 10-2 VF (P < .01). The minimum macular ganglion cell-inner plexiform layer thickness (P = .04), any central 12 points depressed <0.5% on 24-2 VF (P < .01), and any central 12 points depressed <5% on 24-2 VF that spatially corresponds to macular ganglion cell-inner plexiform layer thinning (P < 0.01) were related factors to the presence of parafoveal scotoma on 10-2 VF.
  
  
  CONCLUSIONS
  Glaucomatous eyes with any abnormal 24-2 VF points on the central 10 degree region that are depressed <0.5% or <5% that correlates to macular ganglion cell-inner plexiform layer thinning should receive attention and be further evaluated with a 10-2 VF test.
authors.affiliation: Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Seoul St Mary's Hospital, Seoul, South Korea.
authors.forename: Hae-Young Lopilly
authors.initials: HY
authors.lastname: Park
authors.affiliation: Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Seoul St Mary's Hospital, Seoul, South Korea.
authors.forename: Bo-Een
authors.initials: BE
authors.lastname: Hwang
authors.affiliation: Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Uijeongbu St Mary's Hospital, Uijeongbu, South Korea.
authors.forename: Hye-Young
authors.initials: HY
authors.lastname: Shin
authors.affiliation: Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Seoul St Mary's Hospital, Seoul, South Korea. Electronic address: ckpark@catholic.ac.kr.
authors.forename: Chan Kee
authors.initials: CK
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D005584:Fovea Centralis; D005901:Glaucoma / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis* / Q000503:physiopathology; D011446:Prospective Studies; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012607:Scotoma / Q000175:diagnosis* / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields / Q000502:physiology*