title: [Serological Investigation of Toxoplasma gondii on Pregnant Women and Toxoplasmosis Suspected Patients Between 2012-2014 Years on a Tertiary Training Hospital].
abstract: OBJECTIVE
  Toxoplasmosis is a zoonotic disease which is still an important health issue in both developing and developed countries. We aimed to evaluate Toxoplasma gondii (T. gondii) seropositivity on toxoplasmosis suspected patients and pregnant women, retrospectively.
  
  
  METHODS
  Blood samples taken from toxoplasmosis suspected patients (n=1296) and pregnant women (1737) on our tertiary training hospital between 2012-2014 years. Anti-T. gondii IgG and IgM seropositivity analyzed with chemiluminescent microparticle immunological assay (CMIA) method. Also IgG avidity index were evaluated on patients who had both antibodies.
  
  
  RESULTS
  Of 1269 toxoplasmosis suspected patients, 37% (n=479) had only T. gondii IgG positive while 1.9% (n=25) had both IgG and IgM antibodies. Of 1737 pregnant women, 24.2% (n=421) had only T. gondii IgG positive while 0.7% (n=13) of women were found positive for both antibodies. None of the total 3033 patients were seropositive for sole IgG antibody. Avidity tests were applied to the double positive patients and low avidity were detected on only one person from each group.
  
  
  CONCLUSIONS
  Nationwide, high throughput, systemic seroprevalance studies is needed in order to take precautions for the public health to protect sensitive groups and pregnant women especially because of congenital toxoplasmosis risk.
authors.affiliation: GATA Haydarpaşa Eğitim Hastanesi, Tıbbi Mikrobiyoloji Servisi, İstanbul, Türkiye. mbselek@gata.edu.tr.
authors.forename: Mehmet Burak
authors.initials: MB
authors.lastname: Selek
authors.forename: Bayhan
authors.initials: B
authors.lastname: Bektöre
authors.forename: Orhan
authors.initials: O
authors.lastname: Baylan
authors.forename: Mustafa
authors.initials: M
authors.lastname: Özyurt
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D000915:Antibody Affinity; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D011634:Public Health; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D014125:Toxoplasmosis, Congenital / Q000517:prevention & control; D055815:Young Adult; D015047:Zoonoses / Q000453:epidemiology / Q000276:immunology
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D007075:Immunoglobulin M