title: Objective assessment of intensive targeted treatment for solar lentigines using intense pulsed light with wavelengths between 500 and 635 nm.
abstract: OBJECTIVE
  Solar lentigines are commonly found in sun-exposed areas of the body including hands, neck, or face. This study evaluates the efficacy of an intense pulsed light (IPL) device, with wavelengths between 500 and 635 nm and delivered with a targeted tip, for the treatment of solar lentigines on Japanese skin.
  
  
  METHODS
  Forty Japanese patients with solar lentigines received one IPL treatment with a targeted treatment tip that emits wavelengths between 500 and 635 nm and contact cooling. Pulses were delivered through a targeted tip to each lentigo until mild swelling and a gray color were observed. Digital photographs and gray level histogram values were taken pre- and post-treatment, and patient assessments were recorded post-treatment.
  
  
  RESULTS
  Significant improvement was observed for all patients in digital photographs and mean values of gray level histograms (P < 0.0001). Ninety percent of patients reported satisfaction with the improvement of the treatment area and convenience of the procedure. Complications were minor and transitory, consisting of a slight burning sensation and mild erythema which resolved within 5 hours of treatment. No serious adverse events were observed.
  
  
  CONCLUSIONS
  A short-wavelength IPL, delivered with a targeted tip and contact cooling, offers a highly efficacious treatment for solar lentigines in Japanese skin with minimal downtime and complications.
authors.affiliation: Clinica Tanaka Plastic, Reconstructive Surgery and Anti-aging Center, Matsumoto, Nagano, 390-0874, Japan.|Department of Dermatology, Tokyo Women's Medical University, Tokyo, 162-8666, Japan.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Tanaka
authors.affiliation: Department of Dermatology, Tokyo Women's Medical University, Tokyo, 162-8666, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Tsunemi
authors.affiliation: Department of Dermatology, Tokyo Women's Medical University, Tokyo, 162-8666, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Kawashima
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D062325:Intense Pulsed Light Therapy / Q000379:methods; D007911:Lentigo / Q000209:etiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D013472:Sunlight / Q000009:adverse effects; D016896:Treatment Outcome
keywords: Asian patients; gray level histogram values; minimally invasive treatment; photorejuvenation; short-wavelength intense pulsed light