title: Impact of a nutrition and physical activity intervention (ENRICH: Exercise and Nutrition Routine Improving Cancer Health) on health behaviors of cancer survivors and carers: a pragmatic randomized controlled trial.
abstract: BACKGROUND
  Physical activity and consuming a healthy diet have clear benefits to the physical and psychosocial health of cancer survivors, with guidelines recognising the importance of these behaviors for cancer survivors. Interventions to promote physical activity and improve dietary behaviors among cancer survivors and carers are needed. The aim of this study was to determine the effects of a group-based, face-to-face multiple health behavior change intervention on behavioral outcomes among cancer survivors of mixed diagnoses and carers.
  
  
  METHODS
  The Exercise and Nutrition Routine Improving Cancer Health (ENRICH) intervention was evaluated using a two-group pragmatic randomized controlled trial. Cancer survivors and carers (n = 174) were randomly allocated to the face-to-face, group-based intervention (six, theory-based two-hour sessions delivered over 8 weeks targeting healthy eating and physical activity [PA]) or wait-list control (after completion of 20-week data collection). Assessment of the primary outcome (pedometer-assessed mean daily step counts) and secondary outcomes (diet and alcohol intake [Food Frequency Questionnaire], self-reported PA, weight, body mass index, and waist circumference) were assessed at baseline, 8-and 20-weeks.
  
  
  RESULTS
  There was a significant difference between the change over time in the intervention group and the control group. At 20 weeks, the intervention group had increased by 478 steps, and the control group had decreased by 1282 steps; this represented an adjusted mean difference of 1761 steps (184 to 3337; P = 0.0028). Significant intervention effects for secondary outcomes, included a half serving increase in vegetable intake (difference 39 g/day; 95 % CI: 12 to 67; P = 0.02), weight loss (kg) (difference -1.5 kg; 95 % CI, -2.6 to -0.3; P = 0.014) and change in body mass index (kg/m(2)) (difference -0.55 kg/m(2); 95 % CI, -0.97 to -0.13; P = 0.012). No significant intervention effects were found for self-reported PA, total sitting time, waist circumference, fruit, energy, fibre, alcohol, meat, or fat consumption.
  
  
  CONCLUSIONS
  The ENRICH intervention was effective for improving PA, weight, body mass index, and vegetable consumption even with the inclusion of multiple cancer types and carers. As an example of successful research translation, the Cancer Council NSW has subsequently adopted ENRICH as a state-wide program.
  
  
  BACKGROUND
  Australian New Zealand Clinical Trials Register identifier: ANZCTRN1260901086257.
authors.affiliation: School of Medicine and Public Health, Priority Research Centre for Health Behavior, Priority Research Centre in Physical Activity and Nutrition, The University of Newcastle, Callaghan, NSW, Australia.|Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.
authors.forename: E L
authors.initials: EL
authors.lastname: James
authors.affiliation: School of Medicine and Public Health, Priority Research Centre for Health Behavior, Priority Research Centre in Physical Activity and Nutrition, The University of Newcastle, Callaghan, NSW, Australia. fiona.stacey@newcastle.edu.au.|Hunter Medical Research Institute, New Lambton Heights, NSW, Australia. fiona.stacey@newcastle.edu.au.
authors.forename: F G
authors.initials: FG
authors.lastname: Stacey
authors.affiliation: Cancer Council New South Wales, Woolloomooloo, NSW, Australia.
authors.forename: K
authors.initials: K
authors.lastname: Chapman
authors.affiliation: Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.|Priority Research Centre for Health Behavior, School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
authors.forename: A W
authors.initials: AW
authors.lastname: Boyes
authors.affiliation: School of Health Sciences, Priority Research Centre in Physical Activity and Nutrition, The University of Newcastle, Callaghan, NSW, Australia.
authors.forename: T
authors.initials: T
authors.lastname: Burrows
authors.affiliation: Centre for Oncology Education and Research Translation (CONCERT), Ingham Institute for Applied Medical Research, UNSW Medicine, Liverpool, NSW, Australia.
authors.forename: A
authors.initials: A
authors.lastname: Girgis
authors.affiliation: Cancer Council New South Wales, Woolloomooloo, NSW, Australia.
authors.forename: G
authors.initials: G
authors.lastname: Asprey
authors.affiliation: Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.
authors.forename: A
authors.initials: A
authors.lastname: Bisquera
authors.affiliation: School of Education, Priority Research Centre in Physical Activity and Nutrition, The University of Newcastle, Callaghan, NSW, Australia.
authors.forename: D R
authors.initials: DR
authors.lastname: Lubans
mesh_terms: D000328:Adult; D000368:Aged; D001315:Australia; D015992:Body Mass Index; D005260:Female; D015438:Health Behavior; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009369:Neoplasms / Q000178:diet therapy* / Q000503:physiopathology / Q000534:rehabilitation*; D009520:New Zealand; D009752:Nutritional Status; D011788:Quality of Life; D017741:Survivors; D014675:Vegetables