title: Quantification of the Visual Field Loss in Retinitis Pigmentosa Using Semi-Automated Kinetic Perimetry.
abstract: To assess quantitatively the natural course of the visual field (VF) loss in patients with retinitis pigmentosa (RP) during 2-year period of observation.
  
  
  
  VFs were obtained by semi-automated kinetic perimetry (SKP) during four examinations of 16 patients suffering from RP. Three stimulus conditions (V4e, III4e and I4e) with a constant stimulus angular velocity of 3°/s were used to assess the hill of vision in both eyes of each patient. The area of each isopter was measured in square degrees and corrected for the individual reaction time (RT).
  
  
  
  There were four patients with mild restriction of VF, six with ring scotomas and six with advanced concentric constrictions of VF. Only I4e isopter area decreased significantly from the first to the last session (p = 0.006), the difference was 154 deg(2) being 13% of initial isopter area. The difference was not significant for V4e and III4e isopters. RT values did not differ significantly between four sessions.
  
  
  
  Only I4e isopter's area was decreased significantly during two years of observation. SKP provides a method of assessment of progression of the VF loss in patients suffering from RP by measurement of the isopters' area over time.
authors.affiliation: a Department of General Ophthalmology , Medical University in Lublin , Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Nowomiejska
authors.affiliation: b Department of Mathematics and Medical Biostatistics , Medical University , Lublin , Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Brzozowska
authors.affiliation: c Department of Ophthalmology , University of Heidelberg , Heidelberg , Germany.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Koss
authors.affiliation: d Casey Eye Institute Oregon Retinal Degeneration Center, Oregon Health & Science University , Portland , USA.
authors.forename: Richard G
authors.initials: RG
authors.lastname: Weleber
authors.affiliation: e Centre for Ophthalmology/Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany; Competence Centre "Vision Research", University of Applied Science , Aalen , Germany.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Schiefer
authors.affiliation: f Department of Neurology , Medical University , Lublin , Poland.
authors.forename: Konrad
authors.initials: K
authors.lastname: Rejdak
authors.affiliation: g Department of Ophthalmology , University of Rostock , Rostock , Germany.
authors.forename: Anselm G
authors.initials: AG
authors.lastname: Juenemann
authors.affiliation: h Human Anatomy Department , Medical University , Lublin , Poland.
authors.forename: Ryszard
authors.initials: R
authors.lastname: Maciejewski
authors.affiliation: a Department of General Ophthalmology , Medical University in Lublin , Poland.|i Department of Experimental Pharmacology , Medical Research Centre, Polish Academy of Sciences , Warsaw , Poland.
authors.forename: Robert
authors.initials: R
authors.lastname: Rejdak
mesh_terms: D000293:Adolescent; D000328:Adult; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012174:Retinitis Pigmentosa / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D012607:Scotoma / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D013997:Time Factors; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields / Q000502:physiology*; D055815:Young Adult
keywords: Isopter; perimetry; reaction time; retinitis pigmentosa; visual field