title: Resection of Late Pulmonary Metastases from Pancreatic Adenocarcinoma: Is Surgery an Option?
abstract: Patients with recurrences from pancreas adenocarcinoma have a poor survival rate despite new chemotherapy treatment options. Recurrences are mainly hepatic metastases or peritoneal dissemination and surgical treatment is not recommended. Late and single metachronous pulmonary recurrences are uncommon and may mimic primary lung carcinoma. We report two patients with late and unique pulmonary metastasis from pancreatic cancer. These two patients underwent surgical resection; three and five years later, they did not experience recurrences. Cases called for a surgical approach in late and unique pulmonary metastases from pancreatic cancer, and paved the way for a prolonged chemotherapy free period.
authors.affiliation: a Department of Gastroenterology and Digestive Oncology, Cochin Teaching Hospital , Paris Descartes University , Paris , France.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Brieau
authors.affiliation: a Department of Gastroenterology and Digestive Oncology, Cochin Teaching Hospital , Paris Descartes University , Paris , France.
authors.forename: Maximilien
authors.initials: M
authors.lastname: Barret
authors.affiliation: b Pathology Department, Cochin Teaching Hospital , Paris Descartes University , Paris , France.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Rouquette
authors.affiliation: a Department of Gastroenterology and Digestive Oncology, Cochin Teaching Hospital , Paris Descartes University , Paris , France.
authors.forename: Johann
authors.initials: J
authors.lastname: Dréanic
authors.affiliation: a Department of Gastroenterology and Digestive Oncology, Cochin Teaching Hospital , Paris Descartes University , Paris , France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Brezault
authors.affiliation: c Department of Thoracic Surgery, Cochin Teaching Hospital , Paris Descartes University , Paris , France.
authors.forename: Jean François
authors.initials: JF
authors.lastname: Regnard
authors.affiliation: a Department of Gastroenterology and Digestive Oncology, Cochin Teaching Hospital , Paris Descartes University , Paris , France.|d U-1016 INSERM, Paris Descartes University , Paris , France.
authors.forename: Romain
authors.initials: R
authors.lastname: Coriat
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000368:Aged; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D012008:Recurrence; D015996:Survival Rate
keywords: Late and unique metastasis; Lung recurrence; Pancreatic cancer; Prolonged survival; Surgical management