title: Alterations in bone marrow metabolism are an early and consistent feature during the development of MGUS and multiple myeloma.
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: C
authors.initials: C
authors.lastname: Ludwig
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: D S
authors.initials: DS
authors.lastname: Williams
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: D B
authors.initials: DB
authors.lastname: Bartlett
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: S J
authors.initials: SJ
authors.lastname: Essex
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: G
authors.initials: G
authors.lastname: McNee
authors.affiliation: School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: J W
authors.initials: JW
authors.lastname: Allwood
authors.affiliation: School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: E
authors.initials: E
authors.lastname: Jewell
authors.affiliation: Department of Haematology, The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
authors.forename: A
authors.initials: A
authors.lastname: Barkhuisen
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: H
authors.initials: H
authors.lastname: Parry
authors.affiliation: Department of Haematology, The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
authors.forename: S
authors.initials: S
authors.lastname: Anandram
authors.affiliation: Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.
authors.forename: P
authors.initials: P
authors.lastname: Nicolson
authors.affiliation: Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.
authors.forename: C
authors.initials: C
authors.lastname: Gardener
authors.affiliation: Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.
authors.forename: F
authors.initials: F
authors.lastname: Seymour
authors.affiliation: Department of Haematology, The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
authors.forename: S
authors.initials: S
authors.lastname: Basu
authors.affiliation: School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: W B
authors.initials: WB
authors.lastname: Dunn
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: P A H
authors.initials: PA
authors.lastname: Moss
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.|Department of Haematology, Birmingham Heartlands Hospital, Birmingham, UK.
authors.forename: G
authors.initials: G
authors.lastname: Pratt
authors.affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
authors.forename: D A
authors.initials: DA
authors.lastname: Tennant
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D001853:Bone Marrow / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D055442:Metabolome; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000378:metabolism* / Q000473:pathology; D009101:Multiple Myeloma / Q000378:metabolism*; D025341:Principal Component Analysis
chemical_list: D014408:Biomarkers, Tumor