title: Clinical Application of AIMS65 Scores to Predict Outcomes in Patients with Upper Gastrointestinal Hemorrhage.
abstract: OBJECTIVE
  To evaluate the ability of the recently proposed albumin, international normalized ratio (INR), mental status, systolic blood pressure, age >65 years (AIMS65) score to predict mortality in patients with acute upper gastrointestinal bleeding (UGIB).
  
  
  METHODS
  AIMS65 scores were calculated in 251 consecutive patients presenting with acute UGIB by allotting 1 point each for albumin level <30 g/L, INR >1.5, alteration in mental status, systolic blood pressure ≤90 mm Hg, and age ≥65 years. Risk stratification was done during the initial 12 hours of hospital admission.
  
  
  RESULTS
  Intensive care unit (ICU) admission, endoscopic therapy, or surgery were required in 51 patients (20.3%), 64 (25.5%), and 12 (4.8%), respectively. The predictive accuracy of AIMS65 scores ≥2 was high for blood transfusion (area under the receiver operator characteristic curve [AUROC], 0.59), ICU admission (AUROC, 0.61), and mortality (AUROC, 0.74). The overall mortality was 10.3% (n=26), and was 3%, 7.8%, 20%, 36%, and 40% for AIMS65 scores of 0, 1, 2, 3, and 4, respectively; these values were significantly higher in those with scores ≥2 (30.9%) than in those with scores <2 (4.5%, p<0.001).
  
  
  CONCLUSIONS
  AIMS65 is a simple, accurate, non-endoscopic risk score that can be applied early (within 12 hours of hospital admission) in patients with acute UGIB. AIMS65 scores ≥2 predict high in-hospital mortality.
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Ragesh Babu
authors.initials: RB
authors.lastname: Thandassery
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Manik
authors.initials: M
authors.lastname: Sharma
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Anil K
authors.initials: AK
authors.lastname: John
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Khalid Mohsin
authors.initials: KM
authors.lastname: Al-Ejji
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Hamidulla
authors.initials: H
authors.lastname: Wani
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Khaleel
authors.initials: K
authors.lastname: Sultan
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Muneera
authors.initials: M
authors.lastname: Al-Mohannadi
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Rafie
authors.initials: R
authors.lastname: Yakoob
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Moutaz
authors.initials: M
authors.lastname: Derbala
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Nazeeh
authors.initials: N
authors.lastname: Al-Dweik
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Muhammed Tariq
authors.initials: MT
authors.lastname: Butt
authors.affiliation: Division of Gastroenterology, Department of Medicine, Hamad General Hospital, Doha, Qatar.
authors.forename: Saad Rashid
authors.initials: SR
authors.lastname: Al-Kaabi
keywords: AIMS65 score; Endoscopy; Mortality; Upper gastrointestinal bleed