title: Intraoperative OCT-Assisted Subretinal Perfluorocarbon Liquid Removal in the DISCOVER Study.
abstract: OBJECTIVE
  To assess the role for intraoperative optical coherence tomography (iOCT) during subretinal perfluoro-n-octane (PFO) removal and evaluate it as an assistive technique during surgical maneuvers.
  
  
  METHODS
  DISCOVER is a prospective study examining microscope-integrated iOCT systems in ophthalmic surgery. The authors report a technique utilizing iOCT guidance and feedback for surgical removal of chronic subretinal PFO.
  
  
  RESULTS
  In this technique, real-time iOCT feedback successfully guided surgical maneuvers to facilitate removal of PFO. Due to the chronicity of the PFO, it was loculated and resistant to multiple maneuvers. Utilizing real-time feedback, additional maneuvers were attempted with feedback to the surgeon regarding the success of removal. Postoperatively, visual acuity improved with anatomic normalization.
  
  
  CONCLUSIONS
  Microscope-integrated iOCT with real-time feedback provided important information to the surgeon that helped facilitate subretinal PFO removal and guided surgical maneuvers.
authors.forename: Adiel G
authors.initials: AG
authors.lastname: Smith
authors.forename: Brian M
authors.initials: BM
authors.lastname: Cost
authors.forename: Justis P
authors.initials: JP
authors.lastname: Ehlers
mesh_terms: D004322:Drainage / Q000379:methods*; D058450:Endotamponade; D005260:Female; D005466:Fluorocarbons; D006801:Humans; D019654:Lens Implantation, Intraocular; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D018918:Phacoemulsification; D011446:Prospective Studies; D012163:Retinal Detachment / Q000601:surgery; D012167:Retinal Perforations / Q000601:surgery*; D025321:Surgery, Computer-Assisted; D041623:Tomography, Optical Coherence; D014821:Vitrectomy
chemical_list: D005466:Fluorocarbons; C073608:perfluorooctane