title: [Cerebral vascular lesions in diabetes mellitus: solved and unresolved questions].
abstract: A review of the Russian and international publications on the frequency, risk factors and characteristics of ischemic stroke in patients with type 2 diabetes mellitus (DM-2) is presented. We present a detailed description of specific risk factors for DM-2 (chronic and acute hyperglycemia, recurrent hypoglycemia, insulin resistance and hyperinsulinemia). Current demands to targeted glucose control in patients who survived vascular events are presented. Attention is drawn to the high frequency of complex multiple vessel lesion in patients with DM-2.
authors.affiliation: Endocrinology Researh Center, Moscow.
authors.forename: I I
authors.initials: II
authors.lastname: Dedov
authors.affiliation: Endocrinology Researh Center, Moscow; Sechenov First Moscow State Medical University, Moscow.
authors.forename: M V
authors.initials: MV
authors.lastname: Shestakova
mesh_terms: D000208:Acute Disease; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000453:epidemiology; D006946:Hyperinsulinism / Q000453:epidemiology; D007003:Hypoglycemia / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D012306:Risk; D020521:Stroke / Q000453:epidemiology*