title: IgG4-Related Lung Disease - Three Untreated Cases with a Benign Outcome.
abstract: IgG4-related disease is a fibroinflammatory disease in which the organs involved share similar pathological findings. Chest disease has been recently clinically and radiologically characterized. Most reports advocate prompt immunosuppressive therapy and describe a fast and good response. We report 3 cases of untreated IgG4-related lung disease that on follow-up have been clinically asymptomatic and radiologically stable or improved. In some cases of IgG4-related lung disease immunosuppressive therapy may not be warranted.
authors.affiliation: Institute of Pulmonary Diseases, Chaim Sheba Medical Center, Ramat Gan, Israel. Electronic address: erik.baltaxe@sheba.health.gov.il.
authors.forename: Erik
authors.initials: E
authors.lastname: Baltaxe
authors.affiliation: Institute of Pulmonary Diseases, Chaim Sheba Medical Center, Ramat Gan, Israel.
authors.forename: Tiberiu
authors.initials: T
authors.lastname: Shulimzon
authors.affiliation: Department of Diagnostic Imaging, Chaim Sheba Medical Center, Ramat Gan, Israel.
authors.forename: Sivan
authors.initials: S
authors.lastname: Lieberman
authors.affiliation: Department of Diagnostic Imaging, Chaim Sheba Medical Center, Ramat Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Judith
authors.initials: J
authors.lastname: Rozenman
authors.affiliation: Institute of Pathology, Chaim Sheba Medical Center, Ramat Gan, Israel.
authors.forename: Marina
authors.initials: M
authors.lastname: Perelman
authors.affiliation: Institute of Pulmonary Diseases, Chaim Sheba Medical Center, Ramat Gan, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Segel
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D008171:Lung Diseases / Q000276:immunology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D007074:Immunoglobulin G
keywords: Enfermedad pulmonar; Immunoglobulin G4; Immunosuppressive therapy; Inmunoglobulina G4; Lung disease; Terapia inmunosupresora