title: Bariatric Surgery in Type 1 Diabetes Mellitus: A Systematic Review.
abstract: Bariatric surgery is recognised as an effective treatment strategy for obese patients with type 2 diabetes mellitus. An increasing number of patients with type 1 diabetes mellitus also suffer with obesity and obesity-associated comorbidities but the role of bariatric and metabolic surgery in this group of patients is unclear. This systematic review investigates published English language scientific literature to understand the results of bariatric surgery in obese patients with type 1 diabetes mellitus. We found that these patients can experience significant weight loss and comorbidity resolution with bariatric surgery. Though most patients also see a decline in total insulin requirement, glycaemic control remains difficult. Most of the patients reported in literature have undergone gastric bypass but data is insufficient to recommend any particular procedure.
authors.affiliation: Bariatric Unit, Sunderland Royal Hospital, Sunderland, SR4 7TP, UK. kamal_mahawar@hotmail.com.
authors.forename: Kamal K
authors.initials: KK
authors.lastname: Mahawar
authors.affiliation: Bariatric Unit, Sunderland Royal Hospital, Sunderland, SR4 7TP, UK.
authors.forename: Nimantha
authors.initials: N
authors.lastname: De Alwis
authors.affiliation: Bariatric Unit, Sunderland Royal Hospital, Sunderland, SR4 7TP, UK.
authors.forename: William R J
authors.initials: WR
authors.lastname: Carr
authors.affiliation: Bariatric Unit, Sunderland Royal Hospital, Sunderland, SR4 7TP, UK.
authors.forename: Neil
authors.initials: N
authors.lastname: Jennings
authors.affiliation: Bariatric Unit, Sunderland Royal Hospital, Sunderland, SR4 7TP, UK.
authors.forename: Norbert
authors.initials: N
authors.lastname: Schroeder
authors.affiliation: Bariatric Unit, Sunderland Royal Hospital, Sunderland, SR4 7TP, UK.
authors.forename: Peter K
authors.initials: PK
authors.lastname: Small
mesh_terms: D050110:Bariatric Surgery; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000628:therapy*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D007328:Insulin / Q000008:administration & dosage; D009765:Obesity / Q000150:complications / Q000601:surgery*; D015431:Weight Loss
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin
keywords: Bariatric surgery; Biliopancreatic diversion; Gastric banding; Gastric bypass; Obesity surgery; Roux-en-Y gastric bypass; Sleeve gastrectomy; Type 1 diabetes mellitus