title: Cu(ii)-catalyzed enantioselective oxygen atom transfer from oxaziridine to oxindole derivatives with chiral phenanthroline.
abstract: In the presence of a Cu(ii) complex of axially chiral, N,N,O-tridentate phenanthroline ligand (S)-2, asymmetric oxygen atom transfer of oxindole derivatives (3) using Davis' oxaziridine (4) occurred to give the corresponding 3-aryl-3-hydroxy-2-oxindole derivatives (1) with excellent enantioselectivity (up to 96% ee). The X-ray crystallographic analysis of the isolated Cu(ii) complex disclosed its N,N,O-tridentate coordination, which is critical to realize effective catalytic activity.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Chikusa, Nagoya 464-8603, Japan. yuki.n@apchem.nagoya-u.ac.jp hnishi@apchem.nagoya-u.ac.jp.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Naganawa
authors.forename: Tomotaka
authors.initials: T
authors.lastname: Aoyama
authors.forename: Hisao
authors.initials: H
authors.lastname: Nishiyama