title: Mesoporous structured estrone imprinted Fe3O4@SiO2@mSiO2 for highly sensitive and selective detection of estrogens from water samples by HPLC.
abstract: In the present work, mesoporous structured estrone (E1) imprinted Fe3O4@SiO2@mSiO2 (MM-MIPs) was prepared and applied as extraction sorbent for selective pre-concentration and specific recognition of E1, 17β-estradiol (E2) and estriol (E3) from water samples. MM-MIPs present higher binding capacity, faster mass transfer and higher extraction efficiency for three estrogens than the non-porous structured Fe3O4@SiO2. Application of MM-MIPs to dispersive solid phase extraction of three estrogens from spiked tap, river and lake water samples at 0.5, 1.0, 10 μg L(-1) resulted in good recoveries ranging from 85% to 95% with relative standard deviation values lower than 6.0% in all cases. Limits of detection were in the range of 0.086-0.43 μg L(-1). The extraction method based on MM-MIPs proved to be a highly-effective enrichment method with enrichment factor about 1700, which is much higher than the value nearly 620 obtained by non-mesoporous Fe3O4@SiO2, during the process of simultaneous separation and sensitive determination of estrogens in complicated water samples. Furthermore, the mesoporous silica could be expanded to imprint other compounds.
authors.affiliation: School of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Lu
authors.affiliation: School of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, China. Electronic address: shfxu1981@163.com.
authors.forename: Shoufang
authors.initials: S
authors.lastname: Xu
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004967:Estrogens / Q000032:analysis*; D004970:Estrone / Q000737:chemistry*; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D054802:Molecular Imprinting; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D014867:Water / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis
chemical_list: D004967:Estrogens; D014874:Water Pollutants, Chemical; D014867:Water; D004970:Estrone; D012822:Silicon Dioxide; D052203:Ferrosoferric Oxide
keywords: Estrogens; Mesoporous silica; Molecularly imprinted polymers; Sample pretreatment