title: [Myocardial infarction due to the left main coronary artery disease in men and women--does accompanying multivessel disease matter?].
abstract: OBJECTIVE
  The prognosis in men and women with myocardial infarction due to left main coronary artery disease (LM) in relation to the presence of isolated LM disease or accompanying one-, two- or multivessel disease.
  
  
  METHODS
  A total of 643 consecutive patients (184 females, 459 males) with acute myocardial infarction due to LM stenosis or occlusion were enrolled. Data on clinical presentation, management and in-hospital mortality derived from the Polish Registry of Acute Coronary Syndromes PL-ACS, data on 12-month mortality derived from the Civil Registry. Patients with isolated LM disease were compared with patients in whom significant stenosis in artery another than LM was present. In-hospital, 30-day, 6- and 12-month mortality in both genders were analyzed.
  
  
  RESULTS
  The disease severity was similar in men and women. No difference in mortality between all subgroups was observed. A non-significant trend towards higher mortality in patients with multivessel disease accompanying to LM disease when compared to patients with isolated LM disease (34.2% vs. 25.2%; p log rank = 0.06).
  
  
  CONCLUSIONS
  There was no difference in in-hospital and long-term mortality between patients with isolated LM disease vs. patients with accompanying multivessel disease. No difference in mortality between genders was noticed. A longer follow-up is needed to confirm the significance of higher mortality in patients with multivessel disease.
authors.forename: Marcin
authors.initials: M
authors.lastname: Sadowski
authors.forename: Wojciech
authors.initials: W
authors.lastname: Gutkowski
authors.forename: Jacek
authors.initials: J
authors.lastname: Kurzawski
authors.forename: Marek
authors.initials: M
authors.lastname: Gierlotka
authors.forename: Lech
authors.initials: L
authors.lastname: Poloński
mesh_terms: D015897:Comorbidity; D003324:Coronary Artery Disease / Q000145:classification / Q000453:epidemiology*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000453:epidemiology*; D011044:Poland / Q000453:epidemiology; D011379:Prognosis; D015996:Survival Rate