title: Advanced Pyoderma Gangrenosum Previously Treated as Squamous Cell Carcinoma.
abstract: Pyoderma gangrenosum is a rare, neutrophilic ulcerative skin disease of unknown etiology often associated with an underlying systemic disease. We present a case of a pyoderma gangrenosum that was initially misdiagnosed and treated as squamous cell carcinoma in another hospital. Multiple surgical treatments triggered postoperative exacerbations and further rapid progression of the lesions. History of pathergy, clinical findings, and histopathological features examined at our Department indicated pyoderma gangrenosum. The diagnosis was confirmed by excluding other diseases that could cause similar-appearing cutaneous lesions. No associated underlying disease was determined. After the diagnosis was confirmed, corticosteroid therapy was initiated until complete remission of ulcerations.
authors.forename: Tamara
authors.initials: T
authors.lastname: Čuk Radović
authors.affiliation: Assist. Prof. Krešimir Kostović, MD, PhD, Department of Dermatology and Venereology, University Hospital Center Zagreb, Universtiy of Zagreb, School of Medicine, Šalata 4, 10000 Zagreb, Croatia; kreso.kostovic@zg.t-com.hr.
authors.forename: Krešimir
authors.initials: K
authors.lastname: Kostović
authors.forename: Jaka
authors.initials: J
authors.lastname: Radoš
authors.forename: Zrinjka
authors.initials: Z
authors.lastname: Paštar
authors.forename: Gordana
authors.initials: G
authors.lastname: Pavliša
authors.forename: Branka
authors.initials: B
authors.lastname: Marinović
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000628:therapy; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D018450:Disease Progression; D006801:Humans; D008297:Male; D017511:Pyoderma Gangrenosum / Q000175:diagnosis* / Q000188:drug therapy; D012871:Skin Diseases / Q000175:diagnosis* / Q000188:drug therapy; D012878:Skin Neoplasms / Q000175:diagnosis / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones