title: [Cross-sectional Study on the Relationship among Syndrome of TCM, BODE Index and Qulity of Life, in Patients with COPD at Stable Phase].
abstract: OBJECTIVE
  To study the syndrome of traditional Chinese medicine (TCM) and relevant indexes of conventional Western medicine for patients with chronic obstructive pulmonary disease (COPD) at stable phase, and further explore the trend of change of the deficiency syndrome of TCM, and the correlation of each syndrome with the BODE index (body mass index, airflow obstruction, dyspnea, and exercise capacity index) and quality of life.
  
  
  METHODS
  300 cases with COPD which were in line with the standard were differentiated to 5 groups (60 cases for each group) by the symptoms. which were Lung Qi deficiency (Group A), Lung and Spleen Qi deficiency (Group B), Lung and Kidney Qi deficiency (Group C), Lung, Spleen and Kidney Qi deficiency (Group D), and deficiency of both Qi and Yin (Group E). Some basic details about the patients were recorded, such as body mass and height. Also BODE index and COPD assessment test were conducted. And then the differences of the indexes among groups, the relationship between the BODE index and the COPD assessment test (CAT) score were analyzed.
  
  
  RESULTS
  Comparison in 5 groups, the body mass index (BMD and forced expiratory volume in 1 s to forced vital capacity ratio (FEV1%) of Group A was the highest, the 6-min walk distance (6MWD) of Group A was the longest, but the degree of dyspnea, BODE index and CAT score of patients in Group A were the lowest (P < 0.05) No statistical significance of above index and score between Group D and E was observed (P > 0.05). In Group D and E, the BMI and FEV1% was the lowest, 6MWD was the shortest, and the degree of dyspnea of patients was the highest (P < 0.05). A positive correlation between BODE index and CAT score observed (r = 0.883, P < 0.05).
  
  
  CONCLUSIONS
  With the progress of COPD, disease from single viscera gradually accumulated to multiple viscera, from Group A --> Group B/Group C --> Group D, with the gradually increasing of BODE index and CAT score.
authors.forename: Hua-nan
authors.initials: HN
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhou
authors.forename: Bing
authors.initials: B
authors.lastname: Mao
mesh_terms: D015992:Body Mass Index; D003430:Cross-Sectional Studies; D004417:Dyspnea; D017079:Exercise Tolerance; D005541:Forced Expiratory Volume; D006801:Humans; D008516:Medicine, Chinese Traditional; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis*; D011788:Quality of Life