title: Underactive Bladder in Older Adults.
abstract: Overactive bladder is one of the most common bladder problems, but an estimated 20 million Americans have underactive bladder (UAB), which makes going to the bathroom difficult, increases the risk of urinary tract infections, and even leads to institutionalization. This article provides an overview of UAB in older adults, and discusses the prevalence, predisposing factors, cause, clinical investigations, and treatments. At present, there is no effective therapy for UAB. A great deal of work still needs to be done on understanding the pathogenesis and the development of effective therapies.
authors.affiliation: Department of Urology, Kaohsiung Chang Gung Memorial Hospital, Chung Shan Medical University Institute of Medicine, Kaohsiung, Taiwan.
authors.forename: Yao-Chi
authors.initials: YC
authors.lastname: Chuang
authors.affiliation: Department of Urology, Fundación Santa Fe de Bogotá University Hospital, Universidad de los Andes School of Medicine, Bogotá, Colombia.
authors.forename: Mauricio
authors.initials: M
authors.lastname: Plata
authors.affiliation: Department of Urology, Aikens Neurourology Research Center, Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA.
authors.forename: Laura E
authors.initials: LE
authors.lastname: Lamb
authors.affiliation: Department of Urology, Aikens Neurourology Research Center, Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA. Electronic address: chancellormb@gmail.com.
authors.forename: Michael B
authors.initials: MB
authors.lastname: Chancellor
mesh_terms: D000328:Adult; D000368:Aged; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D015444:Exercise; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology; D018721:Muscarinic Agonists / Q000009:adverse effects / Q000627:therapeutic use*; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000503:physiopathology*; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000503:physiopathology*; D001745:Urinary Bladder Diseases / Q000150:complications / Q000628:therapy*
chemical_list: D002800:Cholinesterase Inhibitors; D018721:Muscarinic Agonists
keywords: Aging; Overactive bladder; Underactive bladder; Urinary incontinence