title: The Infectious Cause of the Chronic Effect.
abstract: While acute infections cause short-term tissue damage, their long-term impact remains unknown. In a recent publication in Cell, Morais da Fonseca et al. (2015) demonstrate disruption of mesenteric lymph nodes and associated lymphatics after Yersinia pseudotuberculosis infection and clearance. This leads to chronic inflammation and an inability to initiate subsequent intestinal immune responses.
authors.affiliation: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030, USA.
authors.forename: Andrea A
authors.initials: AA
authors.lastname: Hill
authors.affiliation: Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX 77030, USA; Biology of Inflammation Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: gretchen.diehl@bcm.edu.
authors.forename: Gretchen E
authors.initials: GE
authors.lastname: Diehl
mesh_terms: D005260:Female; D000069196:Gastrointestinal Microbiome; D006801:Humans; D007154:Immune System Diseases / Q000382:microbiology* / Q000473:pathology*; D008206:Lymphatic Diseases / Q000473:pathology*; D008297:Male; D015011:Yersinia pseudotuberculosis / Q000502:physiology*; D015012:Yersinia pseudotuberculosis Infections / Q000276:immunology*