title: Evaluation of Hepatitis C Patients in the Direct-Acting Antiviral Era.
abstract: Hepatitis C is a major worldwide cause of liver morbidity and mortality. A substantial proportion of infected patients will develop chronic disease, which may progress over decades to cirrhosis. This can lead to decompensation and hepatocellular carcinoma. With the advent of the direct-acting antivirals, hepatitis C has become increasingly curable with limited adverse events and a shorter duration of therapy. This review discusses the evaluation process of the hepatitis C patient in the direct-acting antiviral era, including screening, clinical evaluation, drug-drug interactions, treatment urgency, and counseling.
authors.affiliation: Department of Medicine, Center for Liver Diseases, University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL 60637, USA. Electronic address: ateriaky@yahoo.com.
authors.forename: Anouar
authors.initials: A
authors.lastname: Teriaky
authors.affiliation: Department of Medicine, Center for Liver Diseases, University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL 60637, USA.
authors.forename: Nancy
authors.initials: N
authors.lastname: Reau
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use*; D037001:Directive Counseling; D004347:Drug Interactions; D016174:Hepacivirus / Q000235:genetics; D019698:Hepatitis C, Chronic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008103:Liver Cirrhosis / Q000473:pathology / Q000821:virology; D008403:Mass Screening; D055118:Medication Adherence
chemical_list: D000998:Antiviral Agents
keywords: Assessment; Diagnosis; Direct-acting antivirals; Evaluation; Hepatitis C