title: A Randomized, Controlled Clinical Trial of Honey-Impregnated Dressing for Treating Diabetic Foot Ulcer.
abstract: OBJECTIVE
  To investigate the effect of Beri-honey-impregnated dressing on diabetic foot ulcer and compare it with normal saline dressing.
  
  
  METHODS
  A randomized, controlled trial.
  
  
  METHODS
  Sughra Shafi Medical Complex, Narowal, Pakistan and Bhatti International Trust (BIT) Hospital, Affiliated with Central Park Medical College, Lahore, from February 2006 to February 2010.
  
  
  METHODS
  Patients with Wagner's grade 1 and 2 ulcers were enrolled. Those patients were divided in two groups; group A (n=179) treated with honey dressing and group B (n=169) treated with normal saline dressing. Outcome measures were calculated in terms of proportion of wounds completely healed (primary outcome), wound healing time, and deterioration of wounds. Patients were followed-up for a maximum of 120 days.
  
  
  RESULTS
  One hundred and thirty six wounds (75.97%) out of 179 were completely healed with honey dressing and 97 (57.39%) out of 169 wtih saline dressing (p=0.001). The median wound healing time was 18.00 (6 - 120) days (Median with IQR) in group A and 29.00 (7 - 120) days (Median with IQR) in group B (p < 0.001).
  
  
  CONCLUSIONS
  The present results showed that honey is an effective dressing agent instead of conventional dressings, in treating patients of diabetic foot ulcer.
authors.affiliation: Department of General Surgery, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Imran
authors.affiliation: Department of Microbiology, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Muhammad Barkaat
authors.initials: MB
authors.lastname: Hussain
authors.affiliation: Department of Biochemistry, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Mukhtiar
authors.initials: M
authors.lastname: Baig
mesh_terms: D000328:Adult; D000368:Aged; D056705:Apitherapy; D001458:Bandages; D017719:Diabetic Foot / Q000150:complications / Q000188:drug therapy; D005260:Female; D016523:Foot Ulcer / Q000209:etiology / Q000628:therapy*; D006722:Honey; D006801:Humans; D008297:Male; D008875:Middle Aged; D010154:Pakistan; D011446:Prospective Studies; D012965:Sodium Chloride / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D012965:Sodium Chloride