title: Chalcane-stilbene conjugates and oligomeric flavonoids from Chinese Dragon's Blood produced from Dracaena cochinchinensis.
abstract: A detailed chemical investigation of Chinese Dragon's Blood, which is a traditional medicine produced form the red resin of Dracaena cochinchinensis, yielded two chalcane-stilbene conjugates, named cochinchinenenes G and H, together with 25 known compounds. The structures of these compounds were determined by spectroscopic examination. HPLC analysis of the resin indicated that the major constituents were a complex mixture of oligomeric polyphenols, which were detected as a broad hump on the base line of a HPLC chromatogram. (13)C NMR analysis indicated that the oligomers were mainly composed of oxygenated chalcane units. This suggestion was supported by the results of a thiol degradation experiment with mercaptoethanol, which yielded a thioether of 4-[(4-hydroxyphenyl)propyl]-3-methoxyphenol. Furthermore, methylation followed by electrospray ionization mass spectroscopic analysis of the resulting fractions established the presence of at least one heptamer of chalcane units.
authors.affiliation: Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-Machi, Nagasaki 852-8521, Japan.
authors.forename: Qian
authors.initials: Q
authors.lastname: Hao
authors.affiliation: Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-Machi, Nagasaki 852-8521, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Saito
authors.affiliation: Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-Machi, Nagasaki 852-8521, Japan.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Matsuo
authors.affiliation: Faculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan 650500, People's Republic of China.
authors.forename: Hai-Zhou
authors.initials: HZ
authors.lastname: Li
authors.affiliation: Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-Machi, Nagasaki 852-8521, Japan. Electronic address: t-tanaka@nagasaki-u.ac.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tanaka
mesh_terms: D047188:Chalcones / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D031409:Dracaena / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D008519:Medicine, Traditional; D010936:Plant Extracts / Q000737:chemistry; D012116:Resins, Plant / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D047188:Chalcones; D005419:Flavonoids; D010936:Plant Extracts; D012116:Resins, Plant; C525191:dragon's blood
keywords: Asparagaceae; Chalcane; Chinese Dragon’s Blood; Dracaena cochinchinensis; Flavonoid; Stilbene