title: Effect of diets enriched with rutin on blood parameters,  oxidative biomarkers and pituitary hormone expression  in silver catfish (Rhamdia quelen).
abstract: The effects of adding rutin to the diet (0, 0.15 or 0.30%) of silver catfish for 21 days on blood parameters, oxidative stress biomarkers and pituitary hormones expression were investigated. Fish that received the diet containing 0.15% rutin exhibited reduced plasma cortisol levels. The levels of lipid peroxidation were lowered in the all tissues of animals receiving the diet containing rutin. Rutin increased the activity of the superoxide dismutase (SOD), catalase (CAT), nonprotein thiols (NPSH), ascorbic acid content (AA) and total reactive antioxidant potential (TRAP) in the brain; glutathione S-transferase (GST) activity and TRAP in the gills; SOD, CAT and GST activity, NPSH, AA levels and TRAP in the liver; CAT and GST activity and TRAP levels in the kidneys; and glutathione peroxidase activity, NPSH, AA levels and TRAP in the muscle. There were no changes regarding the expression of growth hormone, prolactin and somatolactin in fish fed with the diet containing rutin when compared with the control. The supplementation of rutin to the diet of fish is beneficial because it increases the antioxidant responses of tissues.
authors.forename: Tanise S
authors.initials: TS
authors.lastname: Pês
authors.forename: Etiane M H
authors.initials: EM
authors.lastname: Saccol
authors.forename: Giovana M
authors.initials: GM
authors.lastname: Ourique
authors.forename: Érika P
authors.initials: ÉP
authors.lastname: Londero
authors.forename: Luciane T
authors.initials: LT
authors.lastname: Gressler
authors.forename: Isabela A
authors.initials: IA
authors.lastname: Finamor
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Rotili
authors.forename: Jaqueline I
authors.initials: JI
authors.lastname: Golombieski
authors.forename: Werner G
authors.initials: WG
authors.lastname: Glanzner
authors.forename: Susana F
authors.initials: SF
authors.lastname: Llesuy
authors.forename: Paulo B D
authors.initials: PB
authors.lastname: Gonçalves
authors.forename: João
authors.initials: J
authors.lastname: Radünz Neto
authors.forename: Bernardo
authors.initials: B
authors.lastname: Baldisserotto
authors.forename: Maria A
authors.initials: MA
authors.lastname: Pavanato
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D002397:Catfishes / Q000097:blood / Q000235:genetics / Q000378:metabolism; D018076:DNA, Complementary / Q000235:genetics; D004032:Diet; D005880:Gills / Q000187:drug effects / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D006854:Hydrocortisone / Q000097:blood; D007668:Kidney / Q000187:drug effects / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D009132:Muscles / Q000187:drug effects / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects*; D010636:Phenols / Q000032:analysis; D010907:Pituitary Hormones / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism; D012431:Rutin / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D015415:Biomarkers; D018076:DNA, Complementary; D010636:Phenols; D010907:Pituitary Hormones; D012333:RNA, Messenger; D012431:Rutin; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005982:Glutathione Transferase; D006854:Hydrocortisone