title: [ROLE OF p53 IN THE REGULATION OF NEURONAL DIFFERENTIATION].
abstract: Beyond the well-known role of p53 as a tumor suppressor, an increasing number of data demonstrated the multiple roles of p53 in the regulation of various aspects of normal life. Diverse effects ofp53 based on different mechanisms its action, such as regulation of genes' transcription, protein-protein interactions and post-translation modifications. In this review, it was summarized recent studies on the mechanisms underlying the p53-dependent regulation of neuronal differentiation.
authors.forename: M B
authors.initials: MB
authors.lastname: Glazova
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D051379:Mice; D018345:Mice, Knockout; D055495:Neurogenesis / Q000502:physiology*; D009474:Neurons / Q000378:metabolism*; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000378:metabolism*
chemical_list: D016159:Tumor Suppressor Protein p53