title: A mammalian pexophagy target.
abstract: Protein ubiquitylation in mammals is known to trigger selective autophagy of peroxisomes through a process termed pexophagy. The physiological peroxisomal target for pexophagy-related ubiquitylation has been controversial, but two studies have now identified the protein PEX5 as the real candidate.
authors.affiliation: Section of Molecular Biology, Division of Biological Sciences, University California, San Diego, California 92093-0322, USA.
authors.forename: Suresh
authors.initials: S
authors.lastname: Subramani
mesh_terms: D000818:Animals; D064007:Ataxia Telangiectasia Mutated Proteins / Q000378:metabolism*; D001343:Autophagy; D006801:Humans; D020675:Peroxisomes / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism*
chemical_list: D017382:Reactive Oxygen Species; D018160:Receptors, Cytoplasmic and Nuclear; D064007:Ataxia Telangiectasia Mutated Proteins