title: Sleep quality in patients with xerostomia: a prospective and randomized case-control study.
abstract: Objectives To investigate sleep quality, anxiety/depression and quality-of-life in patients with xerostomia. Materials and methods This prospective, observational, cross-sectional study was conducted among a group of xerostomia patients (n = 30) compared with 30 matched control subjects. The following evaluation scales were used to assess the psychological profile of each patient: the Hospital Anxiety and Depression Scale, the Oral Health Impact Profile-14 (OHIP-14), the Xerostomia Inventory, the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS). Results The PSQI obtained 5.3 3 ± 1.78 for patients with xerostomia compared with 4.26 ± 1.01 for control subjects (p = 0.006); ESS obtained 5.7 ± 2.1 for test patients vs 4.4 0 ± 1 for control subjects (p = 0.010). Statistical regression analysis showed that xerostomia was significantly associated with depression (p = 0.027). Conclusions Patients with xerostomia exhibited significant decreases in sleep quality compared with control subjects.
authors.affiliation: a Oral Medicine University , Murcia , Spain ;
authors.forename: Pia
authors.initials: P
authors.lastname: Lopez-Jornet
authors.affiliation: a Oral Medicine University , Murcia , Spain ;
authors.forename: Maira
authors.initials: M
authors.lastname: Lucero Berdugo
authors.affiliation: a Oral Medicine University , Murcia , Spain ;
authors.forename: Alba
authors.initials: A
authors.lastname: Fernandez-Pujante
authors.affiliation: a Oral Medicine University , Murcia , Spain ;
authors.forename: Castillo Felipe
authors.initials: CF
authors.lastname: C
authors.affiliation: a Oral Medicine University , Murcia , Spain ;
authors.forename: Zamora
authors.initials: Z
authors.lastname: Lavella C
authors.affiliation: a Oral Medicine University , Murcia , Spain ;
authors.forename: Pons-Fuster
authors.initials: PF
authors.lastname: A
authors.affiliation: b Unidad De Estomatología, Hospital Universitario Dr Peset Valencia , Spain.
authors.forename: Silvestre Rangil
authors.initials: SR
authors.lastname: J
authors.affiliation: b Unidad De Estomatología, Hospital Universitario Dr Peset Valencia , Spain.
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Silvestre
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000428:Alcohol Drinking; D001007:Anxiety / Q000523:psychology; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D003863:Depression / Q000523:psychology; D009909:Oral Health; D011446:Prospective Studies; D011788:Quality of Life; D012890:Sleep / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology; D012893:Sleep Wake Disorders / Q000150:complications / Q000523:psychology; D012907:Smoking; D014987:Xerostomia / Q000150:complications / Q000523:psychology
keywords: Xerostomia; anxiety; depression; oral quality-of-life; sleep; sleep disorders