title: [Peritoneal dialysis adequacy in pediatrics. From the peritoneal equilibration test to the aquaporins].
abstract: An evaluation of the characteristics of peritoneal solute and water transport is essential to assess the suitability of prescribing dialysis in patients suffering from chronic renal disease. There are currently a series of models to perform this evaluation. The peritoneal equilibration test (PET) evaluates the peritoneal transport capacity, classifying the patients into four transport categories: high, high-average, low-average, and low. The short PET enables the same evaluation to be made in only 2hours, and has been validated in paediatric patients. On the other hand, the MiniPET provides additional information by evaluating the free water transport capacity by the ultra-small pores, and the Accelerated Peritoneal Examination Time (APEX) evaluates the time when the glucose and urea equilibration curves cross, and has been proposed as the optimum dwell time to achieve adequate ultrafiltration. An analysis is presented on the current information on these diagnostic methods as regards free water transport via aquaporins, which could be an important tool in optimising solute and water transport in patients on chronic peritoneal dialysis, particularly as regards the cardiovascular prognosis.
authors.affiliation: Programa de Especialista en Nefrología Pediátrica, Escuela de Postgrado, Facultad de Medicina, Universidad de Chile, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile. Electronic address: lbolte3@gmail.com.
authors.forename: Lillian
authors.initials: L
authors.lastname: Bolte
authors.affiliation: Departamento de Pediatría y Cirugía Infantil Oriente, Facultad de Medicina, Universidad de Chile, Hospital Dr. Luis Calvo Mackenna, Santiago, Chile.
authors.forename: Francisco
authors.initials: F
authors.lastname: Cano
mesh_terms: D020346:Aquaporins / Q000378:metabolism*; D001692:Biological Transport; D002648:Child; D015314:Dialysis Solutions; D006801:Humans; D008954:Models, Biological; D010530:Peritoneal Dialysis / Q000379:methods*; D051436:Renal Insufficiency, Chronic / Q000628:therapy*; D014867:Water / Q000378:metabolism
chemical_list: D020346:Aquaporins; D015314:Dialysis Solutions; D014867:Water
keywords: APEX; Diálisis peritoneal; Mini PET; Peritoneal dialysis; Peritoneal equilibration test; Short PET; Test de equilibrio peritoneal