title: Antracyclin toxicity in a child with primitive neuroectodermal tumor of the chest wall with and brain metastasis.
abstract: Chemotherapy regimens, including doxorubicin used in primitive neuroectodermal tumor's (PNET) treatment can cause life-threatening disorders in cardiac functions. Follow-up of cardiac functions in the clinical course is very important during treatment with ejection fraction (EF) and shortening fraction (SF). However, sometimes the detection of cardiac failure with EF and SF cannot be possible. In this condition, we may need new evaluation test. Herein, we wanted to present a child with PNET of the chest wall suffered from antracycline toxicity and indicate that close monitoring of cardiac function could be important.
authors.affiliation: Department of Pediatric Oncology, Gülhane Military Medical Academy, Ankara, Turkey.
authors.forename: Erman
authors.initials: E
authors.lastname: Atas
authors.forename: Vural
authors.initials: V
authors.lastname: Kesik
mesh_terms: D018943:Anthracyclines / Q000009:adverse effects* / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000556:secondary; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D018242:Neuroectodermal Tumors, Primitive / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000556:secondary; D011859:Radiography; D013899:Thoracic Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D035441:Thoracic Wall / Q000473:pathology
chemical_list: D018943:Anthracyclines