title: Streptavidin functionalized nickel nanowires: A new ferromagnetic platform for biotinylated-based assays.
abstract: Herein we present highly stable ferromagnetic nickel nanowires modified with streptavidin (NiNW-STR). This versatile functionalized nanomaterial works as an excellent biosensing platform for the immobilization of a wide range of biotinylated molecules. Moreover, these NWs can be employed in magnetic-based assays. Different proofs-of-concept such as streptavidin-biotin assays and capture of single and double stranded DNA were successfully carried out, corroborating NiNW-STR usefulness. Moreover, repeatability and stability studies were also effectively performed.
authors.affiliation: DropSens, S.L., Edificio CEEI, Parque Tecnológico de Asturias, 33428 Llanera, Asturias, Spain. Electronic address: mmpereira@dropsens.com.
authors.forename: M M P S
authors.initials: MM
authors.lastname: Neves
authors.affiliation: DropSens, S.L., Edificio CEEI, Parque Tecnológico de Asturias, 33428 Llanera, Asturias, Spain.
authors.forename: M B
authors.initials: MB
authors.lastname: González-García
authors.affiliation: DropSens, S.L., Edificio CEEI, Parque Tecnológico de Asturias, 33428 Llanera, Asturias, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Hernández-Santos
authors.affiliation: DropSens, S.L., Edificio CEEI, Parque Tecnológico de Asturias, 33428 Llanera, Asturias, Spain. Electronic address: pfanjul@dropsens.com.
authors.forename: P
authors.initials: P
authors.lastname: Fanjul-Bolado
mesh_terms: D015374:Biosensing Techniques; D001710:Biotin / Q000737:chemistry; D019921:Biotinylation; D061925:Immobilized Nucleic Acids / Q000737:chemistry; D060328:Magnetic Phenomena; D059346:Magnets; D053770:Nanowires / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D019809:Streptavidin / Q000737:chemistry*
chemical_list: D061925:Immobilized Nucleic Acids; D001710:Biotin; D009532:Nickel; D019809:Streptavidin
keywords: Bioconjugation; Magnetic assays; Nanomaterials; Nickel nanowires; Screen-printed electrodes; Streptavidin