title: Eosinophilic oesophagitis: a systematic review for otolaryngologists.
abstract: BACKGROUND
  Eosinophilic oesophagitis is a chronic, immune/antigen-mediated oesophageal disease, only recently, but increasingly, recognised in the world literature. It is diagnosed and managed primarily by medical gastroenterologists and allergy specialists, and is a distinct disease entity, affecting both children and adults. Few studies have been published in otolaryngology journals, although otolaryngologists will encounter patients with undiagnosed eosinophilic oesophagitis. Patients may present with dysphagia, bolus obstruction or with other ENT disorders, such as atopic rhinitis, reflecting the underlying systemic allergic disorder.
  
  
  OBJECTIVE
  This paper systematically reviews the evidence base published on the epidemiology, clinical presentation, diagnosis, treatment and prognosis of eosinophilic oesophagitis, particularly as it relates to otolaryngology practice.
authors.affiliation: Department of ENT,James Cook University Hospital,Middlesbrough,UK.
authors.forename: M
authors.initials: M
authors.lastname: Bahgat
authors.affiliation: Department of ENT,James Cook University Hospital,Middlesbrough,UK.
authors.forename: N
authors.initials: N
authors.lastname: Dawe
authors.affiliation: Department of ENT,James Cook University Hospital,Middlesbrough,UK.
authors.forename: L
authors.initials: L
authors.lastname: Flood
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001688:Biological Products / Q000627:therapeutic use; D001707:Biopsy, Needle; D002648:Child; D003680:Deglutition Disorders / Q000209:etiology / Q000503:physiopathology; D004032:Diet; D057765:Eosinophilic Esophagitis / Q000175:diagnosis* / Q000628:therapy*; D004945:Esophagoscopy / Q000379:methods*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010036:Otolaryngology / Q000193:education*; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones; D001688:Biological Products
keywords: Allergy; Dysphagia; Eosinophilic Esophagitis; Esophagitis; Gastro-Esophageal Reflux; Meta-Analysis as Topic; Otolaryngology; Randomized Controlled Trials as Topic; Review; Systematic