title: One-year follow-up of Atraumatic Restorative Treatment(ART) for dental caries in children undergoing oncohematological treatment: a pragmatic trial.
abstract: BACKGROUND
  The oral condition in children undergoing oncohematological treatment can have a negative impact on the course of disease. Little is known about survival of tooth restorations in these patients. The aim of this study was to evaluate the longevity of restorations and sealants performed by Atraumatic Restoration Treatment (ART) in patients undergoing oncohematological treatment.
  
  
  METHODS
  ART single surface restorations and sealants were performed in the experimental group (E), which comprised children (2-13 years old) undergoing oncohematological treatment, and in the control group (C), in which patients did not undergo such treatment. The same examiner evaluated the ART at 1, 3, 6 and 12 months after preparation, using the same criteria for restorations and sealants. ART was successful if the sealant or restoration did not need a repair in the follow-up assessment. Descriptive, bivariate and Cox's proportional hazard analyses were performed at a significance level of 5 %.
  
  
  RESULTS
  The two groups, one including 24 children (E) and the other 14 children (C), received 101 and 52 ART procedures, respectively. The success rates were 95.0 % (E) and 100 % (C) at 1 month (P = 0.233); 81.2 % (E) and 92.3 % (C) at 3 months (P = 0.009); 72.2 % (E) and 80.8 % (C) at 6 months (P = 0.050) and 48.5 % (E) and 73.1 % (C) at 12 months (P = 0.001). The final Cox's regression model for occurrence of ART failure needing repair did not show differences between groups (E: OR = 1.6, 95 % CI 0.8-2.9); primary teeth had a shorter survival than permanent teeth (OR = 2.1, 95 % CI 1.2-3.7).
  
  
  CONCLUSIONS
  Oncohematological treatment did not interfere with the longevity of ART restorations and sealants, which suggests the potential use of this technique in children undergoing chemotherapy.
  
  
  BACKGROUND
  Brazilian Clinical Trials Registry (REBEC) RBR-2c3c52. Registered 5 June 2014. http://www.ensaiosclinicos.gov.br/rg/RBR-2c3c52/.
authors.affiliation: Health Sciences Graduate Program, University of Brasília, Brasília, Federal District, Brazil. cintiafg@uol.com.br.|, Avenida Teotônio Segurado, Cj. 01, Lt. 01, Sl. 508, Plano Diretor Sul, Palmas, TO, CEP: 77061-002, Brazil. cintiafg@uol.com.br.
authors.forename: Cíntia Ferreira
authors.initials: CF
authors.lastname: Gonçalves
authors.affiliation: Dentistry Graduate Program, São Leopoldo MandicUniversity, Campinas, São Paulo, Brazil. marianalindemaier@hotmail.com.
authors.forename: Mariana Vargas Lindemaier
authors.initials: MV
authors.lastname: E Silva
authors.affiliation: Division of Pediatric Dentistry, Faculdade de Odontologia, Universidade Federal de Goiás, Goiânia, Goiás, Brazil. lsucasas@ufg.br.
authors.forename: Luciane Rezende
authors.initials: LR
authors.lastname: Costa
authors.affiliation: Health Sciences Graduate Program, University of Brasília, Brasília, Federal District, Brazil. ayrtontoledo@gmail.com.
authors.forename: Orlando Ayrton
authors.initials: OA
authors.lastname: de Toledo
mesh_terms: D002648:Child; D057087:Dental Atraumatic Restorative Treatment / Q000379:methods; D003731:Dental Caries / Q000628:therapy; D019232:Dental Restoration Failure; D005500:Follow-Up Studies; D019337:Hematologic Neoplasms / Q000628:therapy; D006801:Humans; D014094:Tooth, Deciduous