title: Quantification of prebiotics in commercial infant formulas.
abstract: Since breastfeeding is not always possible, infant formulas (IFs) are supplemented with prebiotic oligosaccharides, such as galactooligosaccharides (GOS) and/or fructooligosaccharides (FOS) to exert similar effects to those of the breast milk. Nowadays, a great number of infant formulas enriched with prebiotics are disposal in the market, however there are scarce data about their composition. In this study, the combined use of two chromatographic methods (GC-FID and HPLC-RID) for the quantification of carbohydrates present in commercial infant formulas have been used. According to the results obtained by GC-FID for products containing prebiotics, the content of FOS, GOS and GOS/FOS was in the ranges of 1.6-5.0, 1.7-3.2, and 0.08-0.25/2.3-3.8g/100g of product, respectively. HPLC-RID analysis allowed quantification of maltodextrins with degree of polymerization (DP) up to 19. The methodology proposed here may be used for routine quality control of infant formula and other food ingredients containing prebiotics.
authors.affiliation: Instituto de Investigación en Ciencias de la Alimentación CIAL, (CSIC-UAM) CEI (UAM+CSIC), C/Nicolás Cabrera, 9, E-28049 Madrid, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Sabater
authors.affiliation: Instituto de Investigación en Ciencias de la Alimentación CIAL, (CSIC-UAM) CEI (UAM+CSIC), C/Nicolás Cabrera, 9, E-28049 Madrid, Spain.
authors.forename: Marin
authors.initials: M
authors.lastname: Prodanov
authors.affiliation: Instituto de Investigación en Ciencias de la Alimentación CIAL, (CSIC-UAM) CEI (UAM+CSIC), C/Nicolás Cabrera, 9, E-28049 Madrid, Spain.
authors.forename: Agustín
authors.initials: A
authors.lastname: Olano
authors.affiliation: Instituto de Investigación en Ciencias de la Alimentación CIAL, (CSIC-UAM) CEI (UAM+CSIC), C/Nicolás Cabrera, 9, E-28049 Madrid, Spain. Electronic address: nieves.corzo@csic.es.
authors.forename: Nieves
authors.initials: N
authors.lastname: Corzo
authors.affiliation: Instituto de Investigación en Ciencias de la Alimentación CIAL, (CSIC-UAM) CEI (UAM+CSIC), C/Nicolás Cabrera, 9, E-28049 Madrid, Spain.
authors.forename: Antonia
authors.initials: A
authors.lastname: Montilla
mesh_terms: D000818:Animals; D005260:Female; D006801:Humans; D007223:Infant; D041943:Infant Formula / Q000737:chemistry*; D008297:Male; D056692:Prebiotics / Q000032:analysis*
chemical_list: D056692:Prebiotics
keywords: FOS; GOS; Infant formula; Maltodextrins; Prebiotics