title: [Association between metabolic syndrome and its components with presbycusis].
abstract: OBJECTIVE
  To investigate the effect of metabolic syndrome and its components on presbycusis.
  
  
  METHODS
  Total of 165 cases and 202 controls were continuously collected in Harbin Ninth Hospital from June 2013 to August 2014, these subjects were investigated and received anthropometry and received biochemical test in hospital laboratory. Statistics analysis was adopted by χ2 test, t test and logistic regression model.
  
  
  RESULTS
  Only triglyceride abnormal proportion of case group was higher than that of control group among components of metabolic syndrome, and it were associated with age-related hearing loss whether before adjustment or not after adjustment, OR (95% CI) were 1.69 (1.09-2.63) and 1.96 (1.08-3.54) respectively, and others were not associated with presbycusis. In addition, among all of the various combinations of the components of the metabolic syndrome, combination of triglycerides and high-density lipoprotein, combination of triglycerides and blood glucose, combination of triglycerides and blood pressure were associated with age-related hearing loss before adjustment and after adjustment, OR were 5.31 (95% CI 1.63-17.27), 2.66 (95% CI 1.04-6.85) and 2.09 (95% CI 1.04-4.18) respectively. Further more, the metabolic syndrome was not statistically associated with presbycusis, OR were 1.27 (95% CI 0.83-1.94) and 0.92 (95% CI 0.54-1.57) respectively before adjustment and after adjustment. In addition, stratified by age, the metabolic syndrome was still not statistically associated with presbycusis in each stratification, OR were 0.89 (95% CI 0.44-1.82) and 1.49 (95% CI 0.67-3.30) respectively.
  
  
  CONCLUSIONS
  The triglyceride was associated with presbycusis. Among all of combinations of the components of the metabolic syndrome, combination of triglycerides and high-density lipoprotein, combination of triglycerides and blood glucose, combination of triglycerides and blood pressure were associated with age-related hearing loss.
authors.forename: Jingbo
authors.initials: J
authors.lastname: Zhao
authors.forename: Mengsi
authors.initials: M
authors.lastname: Zhang
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Li
authors.forename: Jiarui
authors.initials: J
authors.lastname: Zhang
authors.forename: Ningning
authors.initials: N
authors.lastname: Wang
authors.forename: Xiaoshan
authors.initials: X
authors.lastname: Yang
mesh_terms: D000367:Age Factors; D000375:Aging; D001786:Blood Glucose / Q000378:metabolism*; D001794:Blood Pressure; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D006801:Humans; D008075:Lipoproteins, HDL; D016015:Logistic Models; D024821:Metabolic Syndrome / Q000097:blood*; D011304:Presbycusis / Q000097:blood* / Q000453:epidemiology; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D008075:Lipoproteins, HDL; D014280:Triglycerides