title: MIRD Pamphlet No. 26: Joint EANM/MIRD Guidelines for Quantitative 177Lu SPECT Applied for Dosimetry of Radiopharmaceutical Therapy.
abstract: The accuracy of absorbed dose calculations in personalized internal radionuclide therapy is directly related to the accuracy of the activity (or activity concentration) estimates obtained at each of the imaging time points. MIRD Pamphlet no. 23 presented a general overview of methods that are required for quantitative SPECT imaging. The present document is next in a series of isotope-specific guidelines and recommendations that follow the general information that was provided in MIRD 23. This paper focuses on (177)Lu (lutetium) and its application in radiopharmaceutical therapy.
authors.affiliation: Department of Medical Radiation Physics, Lund University, Lund, Sweden michael.ljungberg@med.lu.se.
authors.forename: Michael
authors.initials: M
authors.lastname: Ljungberg
authors.affiliation: Radiology Department, Medical Imaging Research Group, University of British Columbia, Vancouver, Canada.
authors.forename: Anna
authors.initials: A
authors.lastname: Celler
authors.affiliation: Department of Nuclear Medicine, Erasmus University Medical Center, Rotterdam, Holland.
authors.forename: Mark W
authors.initials: MW
authors.lastname: Konijnenberg
authors.affiliation: Easterly Scientific, Knoxville, Tennessee; and.
authors.forename: Keith F
authors.initials: KF
authors.lastname: Eckerman
authors.affiliation: Department of Radiology, University of Michigan Medical School, Ann Arbor, Michigan.
authors.forename: Yuni K
authors.initials: YK
authors.lastname: Dewaraja
authors.affiliation: Department of Medical Radiation Physics, Lund University, Lund, Sweden.
authors.forename: Katarina
authors.initials: K
authors.lastname: Sjögreen-Gleisner
authors.forename: Wesley E
authors.initials: WE
authors.lastname: Bolch
authors.forename: A Bertrand
authors.initials: AB
authors.lastname: Brill
authors.forename: Frederic
authors.initials: F
authors.lastname: Fahey
authors.forename: Darrell R
authors.initials: DR
authors.lastname: Fisher
authors.forename: Robert
authors.initials: R
authors.lastname: Hobbs
authors.forename: Roger W
authors.initials: RW
authors.lastname: Howell
authors.forename: Ruby F
authors.initials: RF
authors.lastname: Meredith
authors.forename: George
authors.initials: G
authors.lastname: Sgouros
authors.forename: Pat
authors.initials: P
authors.lastname: Zanzonico
authors.forename: Klaus
authors.initials: K
authors.lastname: Bacher
authors.forename: Carlo
authors.initials: C
authors.lastname: Chiesa
authors.forename: Glenn
authors.initials: G
authors.lastname: Flux
authors.forename: Michael
authors.initials: M
authors.lastname: Lassmann
authors.forename: Lidia
authors.initials: L
authors.lastname: Strigari
authors.forename: Stephan
authors.initials: S
authors.lastname: Walrand
mesh_terms: D000818:Animals; D002138:Calibration; D004282:Documentation; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008187:Lutetium / Q000627:therapeutic use*; D019047:Phantoms, Imaging; D017785:Photons; D017410:Practice Guidelines as Topic; D011868:Radioisotopes / Q000627:therapeutic use*; D011874:Radiometry; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D011879:Radiotherapy Dosage; D012542:Scattering, Radiation; D012958:Societies, Scientific; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation / Q000379:methods*
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals; D008187:Lutetium
keywords: SPECT/CT; endocrine; guideline; image processing; lutetium; oncology; quantitative SPECT; radiobiology/dosimetry; radionuclide therapy