title: Negative pressure wound therapy and skin grafting for necrotizing fasciitis in a patient with rheumatoid arthritis treated with abatacept: A case report.
abstract: Herein, we present a case of necrotizing fasciitis (NF) in a patient with rheumatoid arthritis (RA) treated with abatacept. Cultures of the patient's leg effusion revealed group A Streptococcus. Treatment included antibiological drugs, repeat debridement, negative pressure wound therapy (NPWT), and skin grafting. This case highlights the need for suspicion of severe bacterial infection for early diagnosis and effective treatment. NF with RA can be treated effectively with repeat debridement and NPWT.
authors.affiliation: a Department of Orthopedic Surgery , Kamagaya General Hospital , Chiba , Japan and.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Mochizuki
authors.affiliation: b Institute of Rheumatology, Tokyo Women's Medical University , Tokyo , Japan.
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ikari
authors.affiliation: a Department of Orthopedic Surgery , Kamagaya General Hospital , Chiba , Japan and.
authors.forename: Ryo
authors.initials: R
authors.lastname: Hiroshima
authors.affiliation: a Department of Orthopedic Surgery , Kamagaya General Hospital , Chiba , Japan and.
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Takaoka
authors.affiliation: a Department of Orthopedic Surgery , Kamagaya General Hospital , Chiba , Japan and.
authors.forename: Kosei
authors.initials: K
authors.lastname: Kawakami
authors.affiliation: a Department of Orthopedic Surgery , Kamagaya General Hospital , Chiba , Japan and.
authors.forename: Naoko
authors.initials: N
authors.lastname: Koenuma
authors.affiliation: a Department of Orthopedic Surgery , Kamagaya General Hospital , Chiba , Japan and.
authors.forename: Mina
authors.initials: M
authors.lastname: Ishibashi
authors.affiliation: b Institute of Rheumatology, Tokyo Women's Medical University , Tokyo , Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Momohara
mesh_terms: D000069594:Abatacept / Q000627:therapeutic use; D000368:Aged; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D003646:Debridement; D019115:Fasciitis, Necrotizing / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D054843:Negative-Pressure Wound Therapy; D016038:Skin Transplantation; D013290:Streptococcal Infections / Q000150:complications / Q000601:surgery*
chemical_list: D018501:Antirheumatic Agents; D000069594:Abatacept
keywords: Abatacept; Necrotizing fasciitis; Negative pressure wound therapy; Rheumatoid arthritis