title: Neural mechanisms supporting maladaptive food choices in anorexia nervosa.
abstract: People routinely make poor choices, despite knowledge of negative consequences. The authors found that individuals with anorexia nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day.
authors.affiliation: Psychology Department, New York University, New York, New York, USA.|Division of Clinical Therapeutics, New York State Psychiatric Institute, New York, New York, USA.
authors.forename: Karin
authors.initials: K
authors.lastname: Foerde
authors.affiliation: Division of Clinical Therapeutics, New York State Psychiatric Institute, New York, New York, USA.|Department of Psychiatry, Columbia University Medical Center, New York, New York, USA.
authors.forename: Joanna E
authors.initials: JE
authors.lastname: Steinglass
authors.affiliation: Department of Psychology, Zuckerman Mind Brain Behavior Institute, and Kavli Institute for Brain Science, Columbia University, New York, New York, USA.
authors.forename: Daphna
authors.initials: D
authors.lastname: Shohamy
authors.affiliation: Division of Clinical Therapeutics, New York State Psychiatric Institute, New York, New York, USA.|Department of Psychiatry, Columbia University Medical Center, New York, New York, USA.
authors.forename: B Timothy
authors.initials: BT
authors.lastname: Walsh
mesh_terms: D000222:Adaptation, Physiological; D000856:Anorexia Nervosa / Q000503:physiopathology*; D003342:Corpus Striatum / Q000503:physiopathology*; D003657:Decision Making / Q000502:physiology; D005518:Food Preferences; D006801:Humans; D009415:Nerve Net / Q000503:physiopathology*; D013217:Starvation / Q000523:psychology*