title: Latent tuberculous infection in schoolchildren and contact tracing in Matlosana, North West Province, South Africa.
abstract: This is a cross-sectional study to estimate the prevalence of latent tuberculous infection (LTBI) and the annual risk of tuberculous infection (ARTI) among a sample of children aged 5 and 7 years in Matlosana, South Africa. LTBI prevalence was significantly higher in children aged 7 years (n = 704) (19.7%, 95%CI 16.75-22.65) than in those aged 5 years (212/1401, 15.1%, 95%CI 13.23-16.97) (P = 0.0075). The ARI was 2.9% (95%CI 2.2-3.6).
authors.affiliation: Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: L
authors.initials: L
authors.lastname: Lebina
authors.affiliation: Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: P M
authors.initials: PM
authors.lastname: Abraham
authors.affiliation: Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: M
authors.initials: M
authors.lastname: Milovanovic
authors.affiliation: Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: K
authors.initials: K
authors.lastname: Motlhaoleng
authors.affiliation: Johns Hopkins University Center for TB Research, Baltimore, Maryland, USA.
authors.forename: R E
authors.initials: RE
authors.lastname: Chaisson
authors.affiliation: Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: M
authors.initials: M
authors.lastname: Rakgokong
authors.affiliation: Johns Hopkins University Center for TB Research, Baltimore, Maryland, USA.
authors.forename: J
authors.initials: J
authors.lastname: Golub
authors.affiliation: Department of Medicine, Klerksdorp-Tshepong Hospital Complex, North West Department of Health, Johannesburg, South Africa.
authors.forename: E
authors.initials: E
authors.lastname: Variava
authors.affiliation: Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa; Johns Hopkins University Center for TB Research, Baltimore, Maryland, USA; Department of Science and Technology/National Research Foundation Centre of Excellence for Biomedical TB Research, University of the Witwatersrand, Johannesburg, South Africa; Soweto Matlosana Collaborative Centre for HIV/AIDS & TB, Medical Research Council, Tygerberg, Cape Town, South Africa.
authors.forename: N A
authors.initials: NA
authors.lastname: Martinson
mesh_terms: D002648:Child; D002675:Child, Preschool; D016358:Contact Tracing / Q000379:methods*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D055985:Latent Tuberculosis / Q000453:epidemiology*; D008297:Male; D012574:Schools; D013019:South Africa / Q000453:epidemiology; D014374:Tuberculin Test