title: Calcifications and tungsten deposits after breast-conserving surgery and intraoperative radiotherapy for breast cancer.
abstract: OBJECTIVE
  To describe the presence of atypical calcifications on post-operative mammography after breast-conserving surgery (BCS) and intraoperative radiotherapy (IORT).
  
  
  METHODS
  We retrospectively include all patients followed after BCS and IORT for breast cancer (n=271). All follow-up mammograms at 6 months after surgery were retrospectively evaluated by two board-certified radiologists. The radiologists had to notify the presence or the absence of atypical calcifications.
  
  
  RESULTS
  Five patients had on follow-up mammography the presence of atypical calcifications. Two patients had a stereotactic breast biopsy. The pathologic examination showed the presence of small tungsten particles located in the breast parenchyma.
  
  
  CONCLUSIONS
  The presence of atypical calcifications after BCS and IORT, presenting as multiple, scattered, round calcifications, should be rated as BIRADS 2 and do not require biopsy. They corresponded on tungsten deposits.
authors.affiliation: Department of Radiology, Institut Paoli-Calmettes, Marseille, France. Electronic address: aureliejalaguier@yahoo.fr.
authors.forename: Aurélie
authors.initials: A
authors.lastname: Jalaguier-Coudray
authors.affiliation: Department of Gynecology, Institut Paoli-Calmettes, Marseille, France. Electronic address: cohenm@ipc.unicancer.fr.
authors.forename: M
authors.initials: M
authors.lastname: Cohen
authors.affiliation: Department of Biopathology, Institut Paoli-Calmettes, Marseille, France. Electronic address: thomassinj@ipc.unicancer.fr.
authors.forename: J
authors.initials: J
authors.lastname: Thomassin-Piana
authors.affiliation: Department of Gynecology, Institut Paoli-Calmettes, Marseille, France; CRCM and Université Aix-Marseille (G.H.), Marseille, France. Electronic address: houvenaeghelg@ipc.unicancer.fr.
authors.forename: G
authors.initials: G
authors.lastname: Houvenaeghel
authors.affiliation: Department of Radiology, Institut Paoli-Calmettes, Marseille, France. Electronic address: mahjoubr@ipc.unicancer.fr.
authors.forename: R
authors.initials: R
authors.lastname: Villard-Mahjoub
authors.affiliation: Department of Radiotherapy, Institut Paoli-Calmettes, Marseille, France. Electronic address: talleta@ipc.unicancer.fr.
authors.forename: A
authors.initials: A
authors.lastname: Tallet
authors.affiliation: Department of Radiotherapy, Institut Paoli-Calmettes, Marseille, France. Electronic address: minsatm@ipc.unicancer.fr.
authors.forename: M
authors.initials: M
authors.lastname: Minsat
authors.affiliation: Department of Radiotherapy, Institut Paoli-Calmettes, Marseille, France. Electronic address: resbeutm@ipc.unicancer.fr.
authors.forename: M
authors.initials: M
authors.lastname: Resbeut
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D002114:Calcinosis / Q000139:chemically induced / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D008327:Mammography; D015412:Mastectomy, Segmental; D008875:Middle Aged; D012189:Retrospective Studies; D014414:Tungsten / Q000009:adverse effects*
chemical_list: D014414:Tungsten
keywords: Breast; Calcification; Intraoperative radiotherapy; Mammography; Tungsten