title: Prothrombin Complex Concentrate for Intracerebral Hemorrhage Secondary to Vitamin K Deficiency Bleeding in a 6-Week-Old Child.
abstract: Four-factor prothrombin complex concentrate is approved for use of life-threatening bleeding secondary to vitamin K antagonism in adults. We describe the use of four-factor prothrombin complex concentrate for hemostasis in a 6-week-old child with life-threatening vitamin K dependent-bleeding who never received vitamin K prophylaxis at birth.
authors.affiliation: Department of Pharmacy, Loyola University Medical Center, Maywood, IL; Department of Emergency Medicine, Loyola University Medical Center, Maywood, IL. Electronic address: Mrech@lumc.edu.
authors.forename: Megan A
authors.initials: MA
authors.lastname: Rech
authors.affiliation: Department of Pharmacy, Loyola University Medical Center, Maywood, IL; Department of Pediatrics, Loyola University Medical Center, Maywood, IL.
authors.forename: Lindsay
authors.initials: L
authors.lastname: Wittekindt
authors.affiliation: Department of Pediatrics, Loyola University Medical Center, Maywood, IL.
authors.forename: Samantha D
authors.initials: SD
authors.lastname: Friedman
authors.affiliation: Stritch School of Medicine, Loyola University Chicago, Chicago, IL.
authors.forename: Kendall
authors.initials: K
authors.lastname: Kling
authors.affiliation: Department of Pediatrics, Loyola University Medical Center, Maywood, IL; Stritch School of Medicine, Loyola University Chicago, Chicago, IL.
authors.forename: David
authors.initials: D
authors.lastname: Ubogy
mesh_terms: D001777:Blood Coagulation / Q000187:drug effects*; D001779:Blood Coagulation Factors / Q000008:administration & dosage*; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007275:Injections, Intravenous; D006475:Vitamin K Deficiency Bleeding / Q000097:blood / Q000150:complications / Q000188:drug therapy*
chemical_list: D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates