title: Some of the most interesting CASP11 targets through the eyes of their authors.
abstract: The Critical Assessment of protein Structure Prediction (CASP) experiment would not have been possible without the prediction targets provided by the experimental structural biology community. In this article, selected crystallographers providing targets for the CASP11 experiment discuss the functional and biological significance of the target proteins, highlight their most interesting structural features, and assess whether these features were correctly reproduced in the predictions submitted to CASP11. Proteins 2016; 84(Suppl 1):34-50. © 2015 The Authors. Proteins: Structure, Function, and Bioinformatics Published by Wiley Periodicals, Inc.
authors.affiliation: Genome Center, University of California, Davis, California, 95616.
authors.forename: Andriy
authors.initials: A
authors.lastname: Kryshtafovych
authors.affiliation: Department of Cell Biology and Molecular Genetics, Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland, 20850.
authors.forename: John
authors.initials: J
authors.lastname: Moult
authors.affiliation: Institute for Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne, NE2 4HH, United Kingdom.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Baslé
authors.affiliation: Broad Institute, Cambridge, Massachusetts, 02142.
authors.forename: Alex
authors.initials: A
authors.lastname: Burgin
authors.affiliation: TimPharma, Santa Clarita, California, 91350.
authors.forename: Timothy K
authors.initials: TK
authors.lastname: Craig
authors.affiliation: Department of Biology, San Diego State University, San Diego, California, 92182.|Department of Computer Science, San Diego State University, San Diego, California, 92182.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Edwards
authors.affiliation: Department of Structural Biology, Weizmann Institute of Science, Rehovot, 76100, Israel.
authors.forename: Deborah
authors.initials: D
authors.lastname: Fass
authors.affiliation: Department of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.
authors.forename: Marcus D
authors.initials: MD
authors.lastname: Hartmann
authors.affiliation: Department of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Korycinski
authors.affiliation: Institute for Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne, NE2 4HH, United Kingdom.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Lewis
authors.affiliation: Beryllium, Bainbridge Island, Washington D.C, 98110.
authors.forename: Donald
authors.initials: D
authors.lastname: Lorimer
authors.affiliation: Department of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.
authors.forename: Andrei N
authors.initials: AN
authors.lastname: Lupas
authors.affiliation: Biomedical Manufacturing Program, CSIRO, Parkville, VIC, Australia.
authors.forename: Janet
authors.initials: J
authors.lastname: Newman
authors.affiliation: Biomedical Manufacturing Program, CSIRO, Parkville, VIC, Australia.
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Peat
authors.affiliation: Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, 21201.
authors.forename: Kurt H
authors.initials: KH
authors.lastname: Piepenbrink
authors.affiliation: Department of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588.
authors.forename: Janani
authors.initials: J
authors.lastname: Prahlad
authors.affiliation: Centro Nactional De Biotecnologia (CNB-CSIC), Madrid, E-28049, Spain.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: van Raaij
authors.affiliation: Department of Biology and Viral Information Institute, San Diego State University, San Diego, California, 92182.
authors.forename: Forest
authors.initials: F
authors.lastname: Rohwer
authors.affiliation: Department of Biology and Viral Information Institute, San Diego State University, San Diego, California, 92182.
authors.forename: Anca M
authors.initials: AM
authors.lastname: Segall
authors.affiliation: Human Longevity Inc, La Jolla, California, 92121.
authors.forename: Victor
authors.initials: V
authors.lastname: Seguritan
authors.affiliation: Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, 21201.|Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, 21201.|Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, 21201.
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Sundberg
authors.affiliation: School of Biosciences, University of Kent, Canterbury, Kent, United Kingdom.
authors.forename: Abhimanyu K
authors.initials: AK
authors.lastname: Singh
authors.affiliation: Department of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Wilson
authors.affiliation: Biozentrum, University of Basel, Basel, 4056, Switzerland. Torsten.Schwede@unibas.ch.|SIB Swiss Institute of Bioinformatics, Basel, 4056, Switzerland. Torsten.Schwede@unibas.ch.
authors.forename: Torsten
authors.initials: T
authors.lastname: Schwede
mesh_terms: D001419:Bacteria / Q000737:chemistry; D019295:Computational Biology / Q000379:methods / Q000706:statistics & numerical data*; D003196:Computer Graphics; D018360:Crystallography, X-Ray; D030562:Databases, Protein; D006801:Humans; D007391:International Cooperation; D008958:Models, Molecular; D015233:Models, Statistical; D017510:Protein Folding; D054730:Protein Interaction Domains and Motifs; D055503:Protein Multimerization; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*; D017386:Sequence Homology, Amino Acid; D012984:Software; D014780:Viruses / Q000737:chemistry
chemical_list: D011506:Proteins
keywords: CASP; NMR; X-ray crystallography; protein structure prediction