title: Chemical Constituents of Plants from the Genus Eupatorium (1904-2014).
abstract: Eupatorium (family: Compositae), which comprises nearly 1200 species, is distributed throughout tropical America, Europe, Africa, and Asia. Up to now, the reported constituents from the genus Eupatorium involve flavonoids, terpenoids, pyrrolizidine alkaloids, phenylpropanoids, quinonoids, essential oils, and some others, altogether more than 300 compounds. Studies have shown that Eupatorium and its active principles possess a wide range of pharmacological activities, such as cytotoxic, antifungal, insecticidal, antibacterial, anti-inflammatory, and antinociceptive activities. Currently, effective monomeric compounds or active parts have been screened for pharmacological activities from Eupatorium in vivo and in vitro. Increasing amount of data supports application and exploitation for new drug development.
authors.affiliation: Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634).
authors.forename: Pei-Yu
authors.initials: PY
authors.lastname: Liu
authors.affiliation: Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634).
authors.forename: Dan
authors.initials: D
authors.lastname: Liu
authors.affiliation: Hebei United University Affiliated Hospital, Tangshan, P. R. China.
authors.forename: Wei-Huan
authors.initials: WH
authors.lastname: Li
authors.affiliation: Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634).
authors.forename: Ting
authors.initials: T
authors.lastname: Zhao
authors.affiliation: Department of Chemistry, Queen's University, Kingston, Ontario K7L 3N6, Canada.
authors.forename: Françoise
authors.initials: F
authors.lastname: Sauriol
authors.affiliation: Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634).|Jealott's Hill International Research Centre, Syngenta, Berkshire RG42 6EY, UK.
authors.forename: Yu-Cheng
authors.initials: YC
authors.lastname: Gu
authors.affiliation: Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634). shiqingwen@hebmu.edu.cn.
authors.forename: Qing-Wen
authors.initials: QW
authors.lastname: Shi
authors.affiliation: Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017 , P. R. China, (phone: +86-311-86265634). zhang-manli@163.com.
authors.forename: Man-Li
authors.initials: ML
authors.lastname: Zhang
mesh_terms: D000700:Analgesics / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D036602:Eupatorium / Q000737:chemistry*; D006801:Humans; D009930:Organic Chemicals / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000700:Analgesics; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D009930:Organic Chemicals; D010936:Plant Extracts
keywords: Cytotoxic activity; Eupatorium; Flavonoids; Insecticidal activity; Pharmacological activity; Terpenoids