title: Open-closed switching of synthetic tubular pores.
abstract: While encouraging progress has been made on switchable nanopores to mimic biological channels and pores, it remains a great challenge to realize long tubular pores with a dynamic open-closed motion. Here we report μm-long, dynamic tubular pores that undergo rapid switching between open and closed states in response to a thermal signal in water. The tubular walls consist of laterally associated primary fibrils stacked from disc-shaped molecules in which the discs readily tilt by means of thermally regulated dehydration of the oligoether chains placed on the wall surfaces. Notably, this pore switching mediates a controlled water-pumping catalytic action for the dehydrative cyclization of adenosine monophosphate to produce metabolically active cyclic adenosine monophosphate. We believe that our work may allow the creation of a variety of dynamic pore structures with complex functions arising from open-closed motion.
authors.affiliation: State Key Laboratory for Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.
authors.forename: Yongju
authors.initials: Y
authors.lastname: Kim
authors.affiliation: Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Jiheong
authors.initials: J
authors.lastname: Kang
authors.affiliation: State Key Laboratory for Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.
authors.forename: Bowen
authors.initials: B
authors.lastname: Shen
authors.affiliation: State Key Laboratory for Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.
authors.forename: Yanqiu
authors.initials: Y
authors.lastname: Wang
authors.affiliation: State Key Laboratory for Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: He
authors.affiliation: State Key Laboratory for Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China.
authors.forename: Myongsoo
authors.initials: M
authors.lastname: Lee
mesh_terms: D000249:Adenosine Monophosphate; D000242:Cyclic AMP / Q000138:chemical synthesis; D006358:Hot Temperature; D058608:Nanopores / Q000648:ultrastructure
chemical_list: D000249:Adenosine Monophosphate; D000242:Cyclic AMP