title: Palladium-Catalyzed Regioselective Diarylation of o-Carboranes By Direct Cage B-H Activation.
abstract: Palladium-catalyzed intermolecular coupling of o-carborane with aromatics by direct cage B-H bond activation has been achieved, leading to the synthesis of a series of cage B(4,5)-diarylated-o-carboranes in high yields with excellent regioselectivity. Traceless directing group -COOH plays a crucial role for site- and di-selectivity of such intermolecular coupling reaction. A Pd(II)-Pd(IV)-Pd(II) catalytic cycle is proposed to be responsible for the stepwise arylation.
authors.affiliation: Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
authors.forename: Yangjian
authors.initials: Y
authors.lastname: Quan
authors.affiliation: Department of Chemistry and State Key Laboratory of Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. zxie@cuhk.edu.hk.
authors.forename: Zuowei
authors.initials: Z
authors.lastname: Xie
keywords: B-H activation; arylation; carborane; coupling reactions; homogeneous catalysis