title: IRE1α Stands astride Many Paths to Insulin Production.
abstract: A new study shows that components of the unfolded protein pathway are needed to help manage the production of vast amounts of insulin by pancreatic β cells in response to glucose stimulation. Read the Research Article.
authors.affiliation: Freelance Science Writer, San Diego, California, United States of America.
authors.forename: Caitlin
authors.initials: C
authors.lastname: Sedwick
mesh_terms: D017398:Alternative Splicing; D000818:Animals; D004268:DNA-Binding Proteins / Q000378:metabolism*; D004722:Endoribonucleases / Q000378:metabolism*; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D050417:Insulin-Secreting Cells / Q000378:metabolism*; D008297:Male; D018384:Oxidative Stress; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism*
chemical_list: D004268:DNA-Binding Proteins; D007328:Insulin; D014157:Transcription Factors; D017346:Protein Serine-Threonine Kinases; D004722:Endoribonucleases