title: Hierarchically Structured Porous Poly(2-oxazoline) Hydrogels.
abstract: A new method for fabricating hydrogels with intricate control over hierarchical 3D porosity using microfiber porogens is presented. Melt electrospinning writing of poly(ε-caprolactone) is used to create the sacrificial template leading to hierarchical structuring consisting of pores inside the denser poly(2-oxazoline) hydrogel mesh. This versatile approach provides new opportunities to create well-defined multilevel control over interconnected pores with diameters in the lower micrometer range inside hydrogels with potential applications as cell scaffolds with tunable diffusion and transport of, e.g., nutrients, growth factors or therapeutics.
authors.affiliation: Nanotechnology and Molecular Science Discipline, Science and Engineering Faculty, Queensland University of Technology, Queensland, 4001, Australia.
authors.forename: Jodie N
authors.initials: JN
authors.lastname: Haigh
authors.affiliation: Nanotechnology and Molecular Science Discipline, Science and Engineering Faculty, Queensland University of Technology, Queensland, 4001, Australia.
authors.forename: Ya-Mi
authors.initials: YM
authors.lastname: Chuang
authors.affiliation: Graduate School of Biomedical Engineering, Faculty of Engineering, University of New South Wales, Sydney, 2052, Australia.
authors.forename: Brooke
authors.initials: B
authors.lastname: Farrugia
authors.affiliation: Supramolecular Chemistry Group, Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, B-9000, Ghent, Belgium.
authors.forename: Richard
authors.initials: R
authors.lastname: Hoogenboom
authors.affiliation: Department for Functional Materials in Medicine and Dentistry, Universität Würzburg, Pleicherwall 2, D97070, Germany.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Dalton
authors.affiliation: Nanotechnology and Molecular Science Discipline, Science and Engineering Faculty, Queensland University of Technology, Queensland, 4001, Australia.
authors.forename: Tim R
authors.initials: TR
authors.lastname: Dargaville
keywords: ;hydrogels; ;melt electrospinning; ;poly(2-oxazoline)s; ;porous materials; fibers