title: Prevalence of Splanchnic Vein Thrombosis in Pancreatitis: A Systematic Review and Meta-Analysis of Observational Studies.
abstract: Splanchnic vein thrombosis (SVT) may be negatively associated with the prognosis of pancreatitis. We performed a systematic review and meta-analysis of literatures to explore the prevalence of SVT in pancreatitis. All observational studies regarding the prevalence of SVT in pancreatitis were identified via PubMed and EMBASE databases. The prevalence of SVT was pooled in the total of patients with pancreatitis. And it was also pooled in the subgroup analyses according to the stage and causes of pancreatitis, location of SVT, and regions where the studies were performed. After the review of 714 studies, 44 studies fulfilled the inclusion criteria. Meta-analyses showed a pooled prevalence of SVT of 13.6% in pancreatitis. According to the stage of pancreatitis, the pooled prevalence of SVT was 16.6% and 11.6% in patients with acute and chronic pancreatitis, respectively. According to the causes of pancreatitis, the pooled prevalence of SVT was 12.2% and 14.6% in patients with hereditary and autoimmune pancreatitis. According to the location of SVT, the pooled prevalence of portal vein, splenic vein, and mesenteric vein thrombosis was 6.2%, 11.2%, and 2.7% in pancreatitis. The prevalence of SVT in pancreatitis was 16.9%, 11.5%, and 8.5% in Europe, America, and Asia, respectively.
authors.affiliation: The 251st Hospital of PLA, Zhangjiakou 075000, China.
authors.forename: Wenda
authors.initials: W
authors.lastname: Xu
authors.affiliation: Department of Gastroenterology, Shenyang General Hospital of PLA, Shenyang 110840, China.
authors.forename: Xingshun
authors.initials: X
authors.lastname: Qi
authors.affiliation: Department of Gastroenterology, Shenyang General Hospital of PLA, Shenyang 110840, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Chen
authors.affiliation: Library of Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Chunping
authors.initials: C
authors.lastname: Su
authors.affiliation: Department of Gastroenterology, Shenyang General Hospital of PLA, Shenyang 110840, China.
authors.forename: Xiaozhong
authors.initials: X
authors.lastname: Guo