title: Increasing antibiotic production yields by favoring the biosynthesis of precursor metabolites glucose-1-phosphate and/or malonyl-CoA in Streptomyces producer strains.
authors.affiliation: Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo, Spain.
authors.forename: Daniel
authors.initials: D
authors.lastname: Zabala
authors.affiliation: Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo, Spain.
authors.forename: Alfredo F
authors.initials: AF
authors.lastname: Braña
authors.affiliation: Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo, Spain.
authors.forename: José A
authors.initials: JA
authors.lastname: Salas
authors.affiliation: Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Méndez
mesh_terms: D000103:Acetyl-CoA Carboxylase / Q000235:genetics / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D005958:Glucosephosphates / Q000096:biosynthesis* / Q000494:pharmacology; D008316:Malonyl Coenzyme A / Q000096:biosynthesis* / Q000494:pharmacology; D010733:Phosphoglucomutase / Q000235:genetics / Q000378:metabolism; D010957:Plasmids / Q000235:genetics; D013302:Streptomyces / Q000201:enzymology* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D005958:Glucosephosphates; D008316:Malonyl Coenzyme A; C031590:glucose-1-phosphate; D010733:Phosphoglucomutase; D000103:Acetyl-CoA Carboxylase