title: Old enemies meet new friends for colon cancer prevention.
abstract: Our studies in mice have suggested that the immunological microenvironment of preneoplastic lesions could determine their fate toward neoplasia or regression. A role for gastrointestinal tract bacteria antigens in modulating cancer-related immune responses in the tumor micro- and macro-environment is emerging, thus opening new possibilities for colon cancer prevention.
authors.affiliation: Laboratory of Pathology; Faculty of Health Sciences; School of Veterinary Medicine; Aristotle University of Thessaloniki ; Thessaloniki, Greece.
authors.forename: Theofilos
authors.initials: T
authors.lastname: Poutahidis
authors.affiliation: Laboratory of Biochemistry and Toxicology; Faculty of Health Sciences; School of Veterinary Medicine; Aristotle University of Thessaloniki ; Thessaloniki, Greece.
authors.forename: Katerina
authors.initials: K
authors.lastname: Angelopoulou
authors.affiliation: Division of Comparative Medicine; Massachusetts Institute of Technology ; Cambridge, MA USA.
authors.forename: Suzan E
authors.initials: SE
authors.lastname: Erdman
keywords: cholera-toxin; colitis; colon cancer; mice; tumor microenvironment