title: Early Psoriatic Arthritis.
abstract: Skin psoriasis is a major risk factor for the development of psoriatic arthritis. Recent studies have shown that delayed diagnosis is associated with long-term adverse outcomes. Screening questionnaires have revealed a potential burden of undiagnosed disease. Lifestyle factors and genetic and soluble biomarkers have come under scrutiny as risk factors. Imaging modalities may have an important role in detecting early change. With more effective treatments, it may be possible to prevent significant joint damage and associated disability. However, the precise nature of accurate and cost-effective screening strategies remains to be determined.
authors.affiliation: Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK. Electronic address: prsnjm@bath.ac.uk.
authors.forename: Neil John
authors.initials: NJ
authors.lastname: McHugh
mesh_terms: D015535:Arthritis, Psoriatic / Q000175:diagnosis*; D003952:Diagnostic Imaging / Q000379:methods*; D042241:Early Diagnosis; D005820:Genetic Testing / Q000379:methods*; D006801:Humans
keywords: Biomarkers; Genetic screening; Psoriasis; Psoriatic arthritis