title: Biocorrosion behavior of biodegradable nanocomposite fibers coated layer-by-layer on AM50 magnesium implant.
abstract: This article demonstrates the use of hybrid nanofibers to improve the biodegradation rate and biocompatibility of AM50 magnesium alloy. Biodegradable hybrid membrane fiber layers containing nano-hydroxyapatite (nHA) particles and poly(lactide)(PLA) nanofibers were coated layer-by-layer (LbL) on AM50 coupons using a facile single-step air jet spinning (AJS) approach. The corrosion performance of coated and uncoated coupon samples was investigated by means of electrochemical measurements. The results showed that the AJS 3D membrane fiber layers, particularly the hybrid membrane layers containing a small amount of nHA (3 wt.%), induce a higher biocorrosion resistance and effectively decrease the initial degradation rate compared with the neat AM50 coupon samples. The adhesion strength improved highly due to the presence of nHA particles in the AJS layer. Furthermore, the long biodegradation rates of AM50 alloy in Hank's balanced salt solution (HBSS) were significantly controlled by the AJS-coatings. The results showed a higher cytocompatibility for AJS-coatings compared to that for neat Mg alloys. The nanostructured nHA embedded hybrid PLA nanofiber coating can therefore be a suitable coating material for Mg alloy as a potential material for biodegradable metallic orthopedic implants.
authors.affiliation: Dept. of Engineering Materials and Mechanical Design, Faculty of Engineering, South Valley University, Qena, Egypt. Electronic address: abd_55@jbnu.ac.kr.
authors.forename: Abdalla
authors.initials: A
authors.lastname: Abdal-Hay
authors.affiliation: Dept. of Mechanical and Biomedical Engineering, American University of Beirut, Beirut, Lebanon; Dept of Mechanical and Industrial Engineering, College of Engineering, Qatar University, P.O. Box 2713, Doha, Qatar.
authors.forename: Anwarul
authors.initials: A
authors.lastname: Hasan
authors.forename: Yu-Kyoung
authors.initials: YK
authors.lastname: Kim
authors.affiliation: Dept of Dental Biomaterials and Institute of Biodegradable Materials, Institute of Oral Bioscience and School of Dentistry (plus BK21 program), Chonbuk National University, Jeon Ju, 561-756, South Korea.
authors.lastname: Yu-Kyoung
authors.affiliation: Dept of Dental Biomaterials and Institute of Biodegradable Materials, Institute of Oral Bioscience and School of Dentistry (plus BK21 program), Chonbuk National University, Jeon Ju, 561-756, South Korea.
authors.forename: Min-Ho
authors.initials: MH
authors.lastname: Lee
authors.affiliation: Dept. of Manufacturing and Industrial Engineering, College of Engineering and Computer Science, University of Texas Rio Grande Valley, 1201 West University Dr., Edinburg, TX 78541-2999, USA.
authors.forename: Abdel Salam
authors.initials: AS
authors.lastname: Hamdy
authors.affiliation: Dept. of Mechanical Engineering, College of Engineering King Saud University, P.O. Box 800, Riyadh 11421, Saudi Arabia; Dept. of Mechanical Engineering, Faculty of Energy Engineering, Aswan University, Aswan, Egypt. Electronic address: kabdelmawgoud@ksu.edu.sa.
authors.forename: Khalil Abdelrazek
authors.initials: KA
authors.lastname: Khalil
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D002460:Cell Line; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D003343:Corrosion; D008274:Magnesium / Q000737:chemistry*; D051379:Mice; D053761:Nanocomposites / Q000737:chemistry*; D057139:Nanofibers / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*
chemical_list: D020099:Coated Materials, Biocompatible; D008274:Magnesium
keywords: Air jet spinning; Biocorrosion; Biodegradable coatings; Implant biomaterials; Magnesium alloys; Nano-hydroxyapatite; Nanofibers