title: Lysoglyceroglycolipids Improve the Intestinal Absorption of Micellar Fucoxanthin by Caco-2 Cells.
abstract: To improve the intestinal absorption of fucoxanthin, we evaluated the effects of dietary glyceroglycolipids on the uptake and secretion of fucoxanthin solubilized in mixed micelles by human intestinal Caco-2 cells. Although digalactosyldiacylglycerol and sulfoquinovosyldiacylglycerol suppressed fucoxanthin uptake and secretion, their lyso-types, digalactosylmonoacylglycerol and sulfoquinovosylmonoa cylglycerol, remarkably enhanced them. Thus, some dietary glyceroglycolipids may be potential enhancers of fucoxanthin bioavailability in humans.
authors.affiliation: National Food Research Institute, National Agriculture and Food Research Organization.
authors.forename: Eiichi
authors.initials: E
authors.lastname: Kotake-Nara
authors.forename: Lina
authors.initials: L
authors.lastname: Yonekura
authors.forename: Akihiko
authors.initials: A
authors.lastname: Nagao
mesh_terms: D001682:Biological Availability; D018938:Caco-2 Cells; D019587:Dietary Supplements; D006017:Glycolipids / Q000494:pharmacology*; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects*; D008823:Micelles; D012995:Solubility; D024341:Xanthophylls / Q000737:chemistry / Q000378:metabolism*
chemical_list: D006017:Glycolipids; D008823:Micelles; D024341:Xanthophylls; C016476:glyceroglucolipids; C025164:fucoxanthin