title: Bowel occult microscopic endometriosis in resection margins in deep colorectal endometriosis specimens has no impact on short-term postoperative outcomes.
abstract: OBJECTIVE
  To evaluate the impact of bowel occult microscopic endometriosis (BOME) implants on postoperative outcomes in patients treated with colorectal resection for deep infiltrating digestive endometriosis.
  
  
  METHODS
  Prospective series of consecutive patients with deep colorectal endometriosis managed by colorectal resection in our department from June 2009 to November 2014 and enrolled in the CIRENDO database (NCT02294825).
  
  
  METHODS
  University tertiary referral center.
  
  
  METHODS
  One hundred three patients managed by colorectal resection for deep infiltrating endometriosis.
  
  
  METHODS
  Histologic examination of colorectal resection specimens.
  
  
  METHODS
  Patient characteristics, preoperative and 1-year postoperative symptoms and intraoperative findings were compared between women with and without BOME on specimen resection margins.
  
  
  RESULTS
  In 15 cases, BOME was found in one (nine cases) or both resection limits (six cases). No statistical significance was found between BOME and height of colorectal anastomosis, length of the resected bowel specimen or depth of rectal wall infiltration. One patient with BOME underwent a second colorectal resection 5 years later for rectal recurrence. Comparison between the rates of dyschezia, diarrhea, constipation, bloating and overall values of GIQLI and KESS scores 1 and 3 years postoperatively showed no statistical significance between women with and without BOME.
  
  
  CONCLUSIONS
  BOME was found in 14.6% of specimen resection margins. No impact on either pelvic or digestive symptoms was observed after 1-year follow-up postoperatively.
  
  
  BACKGROUND
  NCT02294825.
authors.affiliation: Department of Gynecology and Obstetrics, Rouen University Hospital, Rouen, France; Research Group 4308, Spermatogenesis and Gamete Quality, IHU Rouen Normandy, IFRMP23, Reproductive Biology Laboratory, Rouen University Hospital, Rouen, France. Electronic address: horace.roman@gmail.com.
authors.forename: Horace
authors.initials: H
authors.lastname: Roman
authors.affiliation: Department of Gynecology and Obstetrics, Rouen University Hospital, Rouen, France.
authors.forename: Clotilde
authors.initials: C
authors.lastname: Hennetier
authors.affiliation: Department of Gynecology and Obstetrics, Rouen University Hospital, Rouen, France.
authors.forename: Basma
authors.initials: B
authors.lastname: Darwish
authors.affiliation: Department of Gynecology and Obstetrics, Rouen University Hospital, Rouen, France; University of Medicine and Pharmacy of Targu Mures, Targu Mures, Romania.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Badescu
authors.affiliation: Department of Pathology, Rouen University Hospital, Rouen, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Csanyi
authors.affiliation: Department of Pathology, Rouen University Hospital, Rouen, France.
authors.forename: Moutaz
authors.initials: M
authors.lastname: Aziz
authors.affiliation: Department of Surgery, Rouen University Hospital, Rouen, France.
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Tuech
authors.affiliation: Department of Gynecology and Obstetrics, Rouen University Hospital, Rouen, France.
authors.forename: Carole
authors.initials: C
authors.lastname: Abo
mesh_terms: D000328:Adult; D003082:Colectomy / Q000009:adverse effects; D003106:Colon / Q000473:pathology / Q000601:surgery*; D003108:Colonic Diseases / Q000175:diagnosis / Q000601:surgery*; D016208:Databases, Factual; D004715:Endometriosis / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D005602:France; D006785:Hospitals, University; D006801:Humans; D011446:Prospective Studies; D012002:Rectal Diseases / Q000175:diagnosis / Q000601:surgery*; D012007:Rectum / Q000473:pathology / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation; D062606:Tertiary Care Centers; D013997:Time Factors; D016896:Treatment Outcome
keywords: Bowel occult microscopic endometriosis; colorectal resection; endometriosis; microscopic implants; recurrence; resection margins