title: Palladium-Catalyzed Carbonylative Annulation Reactions Using Aryl Formate as a CO Source: Synthesis of 2-Substituted Indene-1,3(2H)-dione Derivatives.
abstract: An efficient synthesis of 2-substituted indene-1,3(2H)-diones from stable and readily available 1-(2-halophenyl)-1,3-diones by employing phenyl formate as a CO source has been developed. The reaction occurred via palladium-catalyzed intramolecular carbonylative annulation using K3PO4 as a base and DMSO as a solvent at 95 °C. In this protocol, the reaction showed a broad substrate scope with good to excellent yields.
authors.affiliation: College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
authors.forename: Jing-Lei
authors.initials: JL
authors.lastname: Chen
authors.affiliation: College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
authors.forename: Zhen-Bang
authors.initials: ZB
authors.lastname: Chen
authors.affiliation: College of Pharmaceutical Sciences, Soochow University , Suzhou 215123, China.
authors.forename: Yong-Ming
authors.initials: YM
authors.lastname: Zhu
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Soochow University , Suzhou 215123, China.
authors.forename: Shun-Jun
authors.initials: SJ
authors.lastname: Ji