title: FlyBase: establishing a Gene Group resource for Drosophila melanogaster.
abstract: Many publications describe sets of genes or gene products that share a common biology. For example, genome-wide studies and phylogenetic analyses identify genes related in sequence; high-throughput genetic and molecular screens reveal functionally related gene products; and advanced proteomic methods can determine the subunit composition of multi-protein complexes. It is useful for such gene collections to be presented as discrete lists within the appropriate Model Organism Database (MOD) so that researchers can readily access these data alongside other relevant information. To this end, FlyBase (flybase.org), the MOD for Drosophila melanogaster, has established a 'Gene Group' resource: high-quality sets of genes derived from the published literature and organized into individual report pages. To facilitate further analyses, Gene Group Reports also include convenient download and analysis options, together with links to equivalent gene groups at other databases. This new resource will enable researchers with diverse backgrounds and interests to easily view and analyse acknowledged D. melanogaster gene sets and compare them with those of other species.
authors.affiliation: Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK.
authors.forename: Helen
authors.initials: H
authors.lastname: Attrill
authors.affiliation: The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Falls
authors.affiliation: Department of Biology, Indiana University, Bloomington, IN 47405, USA.
authors.forename: Joshua L
authors.initials: JL
authors.lastname: Goodman
authors.affiliation: Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK.
authors.forename: Gillian H
authors.initials: GH
authors.lastname: Millburn
authors.affiliation: Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK.
authors.forename: Giulia
authors.initials: G
authors.lastname: Antonazzo
authors.affiliation: Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK.
authors.forename: Alix J
authors.initials: AJ
authors.lastname: Rey
authors.affiliation: Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK sjm41@cam.ac.uk.
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Marygold
mesh_terms: D000818:Animals; D030541:Databases, Genetic; D029721:Drosophila Proteins / Q000235:genetics; D004331:Drosophila melanogaster / Q000235:genetics*; D017344:Genes, Insect
chemical_list: D029721:Drosophila Proteins