title: [Recent Advances in Vaccines and Drugs Against the Ebola Virus].
abstract: The Ebola virus belongs to the Filovirus family, which causes Ebola hemorrhagic fever (mortality, 25%-90%). An outbreak of infection by the Ebola virus is sweeping across West Africa, leading to high mortality and worldwide panic. The Ebola virus has caused a serious threat to public health, so intensive scientific studies have been carried out. Several vaccines (e.g., rVSV-ZEBOV, ChAd3-ZEBOV) have been put into clinical trials and antiviral drugs (e.g., TKM-Ebola, ZMAPP) have been administered in the emergency setting to patients infected by the Ebola virus. Here, recent advances in vaccines and drugs against the Ebola virus are reviewed.
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhu
authors.forename: Chenguang
authors.initials: C
authors.lastname: Yao
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Wei
authors.forename: Zheng
authors.initials: Z
authors.lastname: Kou
authors.forename: Kanghong
authors.initials: K
authors.lastname: Hu
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000008:administration & dosage*; D046129:Ebola Vaccines / Q000008:administration & dosage / Q000235:genetics / Q000276:immunology*; D029043:Ebolavirus / Q000187:drug effects / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D019142:Hemorrhagic Fever, Ebola / Q000188:drug therapy* / Q000517:prevention & control / Q000821:virology; D006801:Humans
chemical_list: D000998:Antiviral Agents; D046129:Ebola Vaccines