title: [Rocuronium anesthesia induced anaphylactic shock: a case report].
abstract: Anaphylaxis is an acute and fatal systemic allergic reaction to an allergen, and it could be an unpredictable and life-threatening cause during anesthesia. The main purpose of this paper is to report a case of anaphylactic shock during the anesthesia induction and to review the prophylaxis and treatment of anaphylactic reactions and anaphylactoid reactions during the anesthesia period. A 63-year-old man, with a mass on his adrenal, was scheduled to a laparoscopic adrenal tumor excision. During the anesthesia induction period, after administrated sulfentanil, propofol and rocuronium, the blood pressure was decreased and the heart rate was increased. Then, the patient had rash on his whole body and developed an anaphylactic shock. After being treated with the anti-allergic agents and norepinephrine, the rash disappeared and the vital sign become stable. The patient felt nothing uncomfortable during the two weeks'follow-up. Anaphylactic reactions and anaphylactoid reactions are not rare during the anesthesia period. The most common inducements are muscle relaxant, latex and antibiotics. Anaphylactic reactions in the perioperative period are often serious and potentially life-threatening conditions, involving multiple organ systems in which the clinical manifestations are the consequence of the release of preformed mediators from mast cells and basophils. Before anesthesia, we should acquire the allergic history. During the anesthesia period, the vital sign and the skin should be observed carefully.
authors.affiliation: Department of Urology, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Min
authors.initials: M
authors.lastname: Qiu
authors.affiliation: Department of Anesthesiology,Peking University Third Hospital, Beijing 100191, China.
authors.forename: Ya-nan
authors.initials: YN
authors.lastname: Zong
authors.affiliation: Department of Urology, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Lu
authors.affiliation: Department of Urology, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Lu-lin
authors.initials: LL
authors.lastname: Ma
authors.affiliation: Department of Anesthesiology,Peking University Third Hospital, Beijing 100191, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zheng
authors.affiliation: Department of Anesthesiology,Peking University Third Hospital, Beijing 100191, China.
authors.forename: Xiang-yang
authors.initials: XY
authors.lastname: Guo
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000601:surgery; D000707:Anaphylaxis / Q000139:chemically induced*; D000732:Androstanols / Q000009:adverse effects*; D000758:Anesthesia / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D059035:Perioperative Period; D000077123:Rocuronium; D012867:Skin / Q000473:pathology
chemical_list: D000732:Androstanols; D000077123:Rocuronium