title: Adhesion with a Sumo.
abstract: Adherens junctions (AJs) play a crucial role in epithelial tissue development and tumorigenesis, and the mechanisms controlling their assembly and disassembly have therefore attracted considerable attention. A paper from Tsur et al. (2015) in this issue of Developmental Cell now shows how sumoylation and desumoylation of E-cadherin promotes its recruitment to AJs.
authors.affiliation: Laboratoire de Biologie du Développement, CNRS-UMR7622, Institut de Biologie Paris-Seine, Université Pierre et Marie Curie, Sorbonne Universités, 75005 Paris, France. Electronic address: michel.labouesse@upmc.fr.
authors.forename: Michel
authors.initials: M
authors.lastname: Labouesse
mesh_terms: D022005:Adherens Junctions / Q000502:physiology*; D000818:Animals; D015820:Cadherins / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000378:metabolism*; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D025841:Small Ubiquitin-Related Modifier Proteins / Q000378:metabolism*
chemical_list: D015820:Cadherins; D029742:Caenorhabditis elegans Proteins; D025841:Small Ubiquitin-Related Modifier Proteins