title: Diagnosis of Food Allergy.
abstract: The prevalence of food allergies has been on the increase over the last 2 decades. Diagnosing food allergies can be complicated, as there are multiple types that have distinct clinical and immunologic features. Food allergies are broadly classified into immunoglobulin E (IgE)-mediated, non-IgE-mediated, or mixed food allergic reactions. This review focuses on the clinical manifestations of the different categories of food allergies and the different tests available to guide the clinician toward an accurate diagnosis.
authors.affiliation: Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Sean N Parker Center for Allergy Research, Stanford University, Stanford University School of Medicine, 269 Campus Drive, CCSR 3215, MC 5366, Stanford, CA 94305-5101, USA. Electronic address: schinths@stanford.edu.
authors.forename: Rebecca Sharon
authors.initials: RS
authors.lastname: Chinthrajah
authors.affiliation: Sean N Parker Center for Allergy Research, Stanford University, Stanford University School of Medicine, 1291 Welch Road, Grant Building S303, Stanford, CA 94305, USA.
authors.forename: Dana
authors.initials: D
authors.lastname: Tupa
authors.affiliation: Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Feinberg School of Medicine, 225 East Chicago Avenue Box 60, Chicago, IL, USA.
authors.forename: Benjamin T
authors.initials: BT
authors.lastname: Prince
authors.affiliation: Sean N Parker Center for Allergy Research, Stanford University, 2500 Grant Road, PEC, 4th Floor Tower C, Mountain View, CA 94040, USA.
authors.forename: Whitney Morgan
authors.initials: WM
authors.lastname: Block
authors.affiliation: Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Sean N Parker Center for Allergy Research, Stanford University, Stanford University School of Medicine, 269 Campus Drive, CCSR 3215, MC 5366, Stanford, CA 94305-5101, USA.
authors.forename: Jaime Sou
authors.initials: JS
authors.lastname: Rosa
authors.affiliation: Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, 240 East Huron Street, M-317, McGaw Pavilion, Chicago, IL 60611, USA.
authors.forename: Anne Marie
authors.initials: AM
authors.lastname: Singh
authors.affiliation: Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, Sean N Parker Center for Allergy Research, Stanford University, Stanford University School of Medicine, 269 Campus Drive, CCSR 3215, MC 5366, Stanford, CA 94305-5101, USA.
authors.forename: Kari
authors.initials: K
authors.lastname: Nadeau
mesh_terms: D000707:Anaphylaxis / Q000175:diagnosis / Q000276:immunology; D002648:Child; D003937:Diagnosis, Differential; D005512:Food Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007159:Immunologic Tests; D008487:Medical History Taking; D010808:Physical Examination
chemical_list: D007073:Immunoglobulin E
keywords: Component testing; Elimination diets; Food allergy; IgE-mediated; Non–IgE-mediated; Oral food challenge; Skin-prick testing