title: Nickel-catalysed para-CH activation of pyridine with switchable regioselective hydroheteroarylation of allylarenes.
abstract: para-CH activation of pyridine with allylbenzene is described by Ni/Al cooperative catalysis in combination with a bulkier NHC ligand and a Lewis acid, leading to linear hydroheteroarylation products. Interestingly, the branch selectivity can be achieved by using the combination of a less sterically hindered amino-NHC ligand and AlMe3 through tandem reaction of facile alkene isomerization followed by a slow CH bond activation process.
authors.affiliation: Institute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China. tgong@gate.sinica.edu.tw.
authors.forename: Wei-Chih
authors.initials: WC
authors.lastname: Lee
authors.affiliation: Institute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China. tgong@gate.sinica.edu.tw and National Chiao Tung University, Dept. of Applied Chemistry, Taiwan.
authors.forename: Chien-Hung
authors.initials: CH
authors.lastname: Chen
authors.affiliation: Institute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China. tgong@gate.sinica.edu.tw.
authors.forename: Cheng-Yuan
authors.initials: CY
authors.lastname: Liu
authors.affiliation: Institute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China. tgong@gate.sinica.edu.tw.
authors.forename: Ming-Shiuan
authors.initials: MS
authors.lastname: Yu
authors.affiliation: Institute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China. tgong@gate.sinica.edu.tw.
authors.forename: Yung-Huei
authors.initials: YH
authors.lastname: Lin
authors.affiliation: Institute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China. tgong@gate.sinica.edu.tw and National Chiao Tung University, Dept. of Applied Chemistry, Taiwan.
authors.forename: Tiow-Gan
authors.initials: TG
authors.lastname: Ong