title: ALL and osteonecrosis.
abstract: In this issue of Blood, Karol et al establish a link between glutamate receptor polymorphisms and osteonecrosis, using a large discovery cohort and 2 validation cohorts. One validation cohort included patients under treatment of acute lymphoblastic leukemia (ALL) and the second is patients receiving glucocorticoid treatment of various other indications.
authors.affiliation: UNIVERSITY OF SOUTHERN CALIFORNIA.
authors.forename: Paul S
authors.initials: PS
authors.lastname: Gaynon
mesh_terms: D015415:Biomarkers / Q000378:metabolism*; D003907:Dexamethasone / Q000009:adverse effects*; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010020:Osteonecrosis / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D016194:Receptors, N-Methyl-D-Aspartate / Q000235:genetics*
chemical_list: D015415:Biomarkers; D005938:Glucocorticoids; D016194:Receptors, N-Methyl-D-Aspartate; D003907:Dexamethasone