title: Man-Made Synthetic Receptors for Capture and Analysis of Ochratoxin A.
abstract: Contemporary analytical methods have the sensitivity required for Ochratoxin A detection and quantification, but direct application of these methods on real samples can be rarely performed because of matrix complexity. Thus, efficient sample pre-treatment methods are needed. Recent years have seen the increasing use of artificial recognition systems as a viable alternative to natural receptors, because these materials seem to be particularly suitable for applications where selectivity for Ochratoxin A is essential. In this review, molecularly imprinted polymers, aptamers and tailor-made peptides for Ochratoxin A capture and analysis with particular attention to solid phase extraction applications will be discussed.
authors.affiliation: Laboratory of Bioanalytical Chemistry, Department of Chemistry, University of Torino, Torino 10125, Italy. claudio.baggiani@unito.it.|Nanostructured Interfaces and Surfaces Interdepartmental Centre, University of Torino, Torino 10125, Italy. claudio.baggiani@unito.it.
authors.forename: Claudio
authors.initials: C
authors.lastname: Baggiani
authors.affiliation: Laboratory of Bioanalytical Chemistry, Department of Chemistry, University of Torino, Torino 10125, Italy. cristina.giovannoli@unito.it.|Nanostructured Interfaces and Surfaces Interdepartmental Centre, University of Torino, Torino 10125, Italy. cristina.giovannoli@unito.it.
authors.forename: Cristina
authors.initials: C
authors.lastname: Giovannoli
authors.affiliation: Laboratory of Bioanalytical Chemistry, Department of Chemistry, University of Torino, Torino 10125, Italy. laura.anfossi@unito.it.|Nanostructured Interfaces and Surfaces Interdepartmental Centre, University of Torino, Torino 10125, Italy. laura.anfossi@unito.it.
authors.forename: Laura
authors.initials: L
authors.lastname: Anfossi
mesh_terms: D052157:Aptamers, Nucleotide / Q000235:genetics; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D015394:Molecular Structure; D009793:Ochratoxins / Q000032:analysis*; D019151:Peptide Library; D062165:Receptors, Artificial / Q000737:chemistry* / Q000235:genetics; D052616:Solid Phase Extraction
chemical_list: D052157:Aptamers, Nucleotide; D009793:Ochratoxins; D019151:Peptide Library; D062165:Receptors, Artificial; C025589:ochratoxin A
keywords: Ochratoxin A; aptamer; binding peptide; molecularly imprinted polymer; mycotoxin; oligosorbent; peptide library; solid phase extraction