title: Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family.
abstract: Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped bacillus. A transmission electron microscopy analysis displayed an abundance of lipid bodies in the cytosol. The genome of the M. tuberculosis K strain was sequenced using two independent sequencing methods (Sanger and Illumina). Here, we present the genomic features of the 4,385,518-bp-long complete genome sequence of M. tuberculosis K (one chromosome, no plasmid, and 65.59 % G + C content) and its annotation, which consists of 4194 genes (3447 genes with predicted functions), 48 RNA genes (3 rRNA and 45 tRNA) and 261 genes with peptide signals.
authors.affiliation: Department of Microbiology, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.|Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Seung Jung
authors.initials: SJ
authors.lastname: Han
authors.affiliation: Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Taeksun
authors.initials: T
authors.lastname: Song
authors.affiliation: ChunLab Inc., Seoul National University, Seoul, South Korea.
authors.forename: Yong-Joon
authors.initials: YJ
authors.lastname: Cho
authors.affiliation: Department of Microbiology, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.|Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Jong-Seok
authors.initials: JS
authors.lastname: Kim
authors.affiliation: Department of Microbiology, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Soo Young
authors.initials: SY
authors.lastname: Choi
authors.affiliation: ChunLab Inc., Seoul National University, Seoul, South Korea.
authors.forename: Hye-Eun
authors.initials: HE
authors.lastname: Bang
authors.affiliation: ChunLab Inc., Seoul National University, Seoul, South Korea.
authors.forename: Jongsik
authors.initials: J
authors.lastname: Chun
authors.affiliation: Korean Institute of Tuberculosis, Korean National Tuberculosis Association, Osong, South Korea.
authors.forename: Gill-Han
authors.initials: GH
authors.lastname: Bai
authors.affiliation: Department of Microbiology, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.|Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Sang-Nae
authors.initials: SN
authors.lastname: Cho
authors.affiliation: Department of Microbiology, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.|Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Sung Jae
authors.initials: SJ
authors.lastname: Shin
keywords: Korean Beijing strain; M. tuberculosis K complete genome; Mycobacterium tuberculosis; Outbreak; TB Beijing family; TB clinical strain