title: A Strained Disilane-Promoted Carboxylation of Organic Halides with CO2 under Transition-Metal-Free Conditions.
abstract: By using a strained four-membered ring disilane (3,4-benzo-1,1,2,2-tetraethyldisilacyclobutene) and CsF, a wide range of aryl, alkenyl, alkynyl, benzyl, allyl, and alkyl halides was successfully carboxylated under an ambient CO2 atmosphere (CO2 balloon) at room temperature within 2 h. In this carboxylation, a highly reactive silyl anion, which is generated from the disilane and CsF, is a key to facilitating the formation of a carbanion equivalent. The resulting anionic species can be trapped with CO2 to produce carboxylic acids with high efficiency.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Mita
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.
authors.forename: Kenta
authors.initials: K
authors.lastname: Suga
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.
authors.forename: Kaori
authors.initials: K
authors.lastname: Sato
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.|ACT-C, Japan Science and Technology Agency (JST), Sapporo 060-0812, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sato