title: Sexually Transmitted Infections.
abstract: Sexually transmitted infections (STIs) remain a significant burden on public health in the United States. Primary prevention counseling with early diagnosis and treatment remain the best methods to decrease the incidence of STIs. Through significant public heath interventions, the incidence of gonorrhea, Chlamydia, and trichomoniasis is decreasing; however, the incidence of primary and secondary syphilis is increasing. Human papilloma virus remains the most common STI, but new vaccinations have the possibility of having a significant impact on this virus's disease potential. This review discusses the most common STIs in the United States, focusing on clinical presentation, diagnosis, and treatment.
authors.affiliation: Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue, Suite 900, Chicago, IL 60611, USA.
authors.forename: Lindsay
authors.initials: L
authors.lastname: Smith
authors.affiliation: Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue, Suite 900, Chicago, IL 60611, USA. Electronic address: m-angarone@northwestern.edu.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Angarone
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002602:Chancroid / Q000150:complications; D002690:Chlamydia Infections / Q000188:drug therapy; D003218:Condylomata Acuminata / Q000628:therapy / Q000821:virology; D016358:Contact Tracing; D004823:Epididymitis / Q000382:microbiology; D005260:Female; D006069:Gonorrhea / Q000150:complications / Q000188:drug therapy; D006100:Granuloma Inguinale / Q000150:complications; D006558:Herpes Genitalis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000150:complications; D008297:Male; D053918:Papillomavirus Vaccines; D013587:Syphilis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D014247:Trichomonas Vaginitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D014456:Ulcer / Q000382:microbiology; D014526:Urethritis / Q000382:microbiology; D002575:Uterine Cervicitis / Q000382:microbiology; D019522:Vaginal Discharge / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000981:Antiprotozoal Agents; D053918:Papillomavirus Vaccines
keywords: Chlamydia; Gonorrhea; HPV; HSV; STI; Syphilis