title: Thoracic aortic aneurysms and pregnancy.
abstract: Half of acute aortic dissection in women under the age of 40 occurs during pregnancy or peripartum period. Marfan syndrome is the most common syndromic presentation of ascending aortic aneurysm, but other syndromes such as vascular Ehlers-Danlos syndrome, Loeys-Dietz syndrome and Turner syndrome also have ascending aortic aneurysms and the associated cardiovascular risk of aortic dissection and rupture. Management of aortic root aneurysm has been established in recent recommendations, even if levels of evidence are weak. Pregnancy and postpartum period should be followed very closely and determined to be at high risk. Guidelines suggest that women with aortopathy should be counseled against the risk of pregnancy and about the heritable nature of the disease prior to pregnancy.
authors.affiliation: CHRU de Lille, hôpital Jeanne-de-Flandres, clinique d'obstétrique, 59037 Lille cedex, France. Electronic address: capucine.coulon@chru-lille.fr.
authors.forename: Capucine
authors.initials: C
authors.lastname: Coulon
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control / Q000601:surgery; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D017545:Aortic Aneurysm, Thoracic / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control / Q000601:surgery; D001019:Aortic Rupture / Q000209:etiology / Q000517:prevention & control / Q000601:surgery; D001021:Aortic Valve / Q000002:abnormalities / Q000000981:diagnostic imaging; D002585:Cesarean Section; D036861:Delivery, Obstetric / Q000379:methods; D004535:Ehlers-Danlos Syndrome / Q000150:complications; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D055947:Loeys-Dietz Syndrome / Q000150:complications; D008382:Marfan Syndrome / Q000150:complications; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control / Q000601:surgery; D018566:Pregnancy, High-Risk; D064186:Prenatal Education; D011446:Prospective Studies; D011644:Puerperal Disorders / Q000453:epidemiology / Q000209:etiology / Q000601:surgery; D012307:Risk Factors; D014424:Turner Syndrome / Q000150:complications; D014463:Ultrasonography; D055815:Young Adult