title: Extensive osteolytic skull base amyloidoma simulating malignancy: A rare pseudotumor producing a diagnostic dilemma.
abstract: Although amyloidomas are quite well-known, intracranial, and especially skull base lesions have been rarely reported. Extensive lesions in the skull base frequently simulate malignancy clinicoradiologically. Diagnosis of these lesions is important as they offer a favorable prognosis. We describe a large infiltrating osteolytic skull base tumor-like lesion in a 45-year-old male without evidence of associated plasma cell dyscrasia. Squash smears and histopathology revealed a plasma cell-rich lesion with abundant amyloid, confirming amyloidoma. To conclude, amyloidoma of the skull base is a rare tumor-like lesion, with timely diagnosis and management offering a good prognosis.
authors.forename: Meetu
authors.initials: M
authors.lastname: Agrawal
authors.affiliation: Department of Pathology, Govind Ballabh Pant Hospital, New Delhi, India.
authors.forename: Vineeta V
authors.initials: VV
authors.lastname: Batra
authors.forename: Kaushik
authors.initials: K
authors.lastname: Majumdar
authors.forename: Lalendra
authors.initials: L
authors.lastname: Upreti
authors.forename: Daljit
authors.initials: D
authors.lastname: Singh
mesh_terms: D000686:Amyloidosis / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D006104:Granuloma, Plasma Cell / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000000981:diagnostic imaging*; D011859:Radiography; D019291:Skull Base / Q000473:pathology; D019292:Skull Base Neoplasms / Q000000981:diagnostic imaging*