Palm oil and cardiovascular disease: a randomized trial of the effects of hybrid palm oil supplementation on human plasma lipid patterns.
This study examines, for the first time, the effect of hybrid Elaeis oleifera × E. guineensis palm oil supplementation on human plasma lipids related to CVD risk factors. One hundred sixty eligible participants were randomized and assigned to one of the two treatments: 25 mL hybrid palm oil (HPO group) or 25 mL extra virgin olive oil (EVOO group) daily for 3 months. Fasting venous samples were obtained at baseline and after 1, 2 and 3 months for measurement of plasma lipids (TC, LDL-C, HDL-C and TAGs). Changes in body mass index and waist circumference were also assessed. Although there was an overall reduction in TC (7.4%, p < 0.001) and in LDL-C (15.6%, p < 0.001), no significant differences were found between the treatment groups in a repeated measures analysis of variance for TC (p = 0.0525), LDL-C (p = 0.2356), HDL-C (p = 0.8293) or TAGs (p = 0.3749). Furthermore, HPO consumption had similar effects on plasma lipids to EVOO, thus providing additional support for the concept that hybrid Elaeis oleifera × E. guineensis palm oil can be seen as a "tropical equivalent of olive oil".
Department of Food Science, University of Udine Via Sondrio 2/a, 33100 Udine, Italy. paololucci2001@yahoo.it.
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Lucci
Department of Nutrition and Biochemistry, Faculty of Sciences, Pontificia Universidad Javeriana, KR 7 # 40-62, Bogota D.C., Colombia.
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Borrero
Department of Internal Medicine, School of Medicine, Pontificia Universidad Javeriana, KR 7 # 40-62, Bogota D.C., Colombia.
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Ruiz
Department of Agricultural, Food, and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131, Ancona, Italy.
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Pacetti
Department of Agricultural, Food, and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131, Ancona, Italy.
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Frega
Department of Microbiology, Faculty of Sciences, Pontificia Universidad Javeriana, KR 7 # 40-62, Bogota D.C., Colombia.
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Diez
Department of Nutrition and Biochemistry, Faculty of Sciences, Pontificia Universidad Javeriana, KR 7 # 40-62, Bogota D.C., Colombia.
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Ojeda
Department of Agricultural, Food, and Environmental Sciences, Università Politecnica delle Marche, Via Brecce Bianche, 60131, Ancona, Italy.
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Gagliardi
Department of Nutrition and Biochemistry, Faculty of Sciences, Pontificia Universidad Javeriana, KR 7 # 40-62, Bogota D.C., Colombia.
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Parra
Department of Nutrition and Biochemistry, Faculty of Sciences, Pontificia Universidad Javeriana, KR 7 # 40-62, Bogota D.C., Colombia.
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Angel
D000368:Aged; D002318:Cardiovascular Diseases / Q000097:blood* / Q000517:prevention & control*; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D000073878:Palm Oil; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*; D012307:Risk Factors
D008055:Lipids; D010938:Plant Oils; D000073878:Palm Oil