Neurobehavioral development of common marmoset monkeys.
Common marmoset (Callithrix jacchus) monkeys are a resource for biomedical research and their use is predicted to increase due to the suitability of this species for transgenic approaches. Identification of abnormal neurodevelopment due to genetic modification relies upon the comparison with validated patterns of normal behavior defined by unbiased methods. As scientists unfamiliar with nonhuman primate development are interested to apply genomic editing techniques in marmosets, it would be beneficial to the field that the investigators use validated methods of postnatal evaluation that are age and species appropriate. This review aims to analyze current available data on marmoset physical and behavioral postnatal development, describe the methods used and discuss next steps to better understand and evaluate marmoset normal and abnormal postnatal neurodevelopment.
Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI.
Nancy
N
Schultz-Darken
Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI.|Medical Scientist Training Program, University of Wisconsin, Madison, WI.
Katarina M
KM
Braun
Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI.|Medical Scientist Training Program, University of Wisconsin, Madison, WI.|Department of Medical Physics, University of Wisconsin, Madison, WI.
Marina E
ME
Emborg
D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D002144:Callithrix / Q000502:physiology* / Q000523:psychology; D008426:Maternal Deprivation; D023421:Models, Animal
assessment scales; behavior; common marmoset; developmental stages; neurodevelopment