Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo.
Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Saxony-Anhalt, Germany.
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Arreba-Tutusaus
Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Saxony-Anhalt, Germany.
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Mack
Department of Internal Medicine III, University of Ulm, Ulm, Baden-Württemberg, Germany.|Department of Pediatric Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
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Bullinger
Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Saxony-Anhalt, Germany.
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Schnöder
Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Saxony-Anhalt, Germany.
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Polanetzki
Department of Cardiology and Angiology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Saxony-Anhalt, Germany.
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Weinert
Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Saxony-Anhalt, Germany.
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Ballaschk
Department of Pediatric Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.
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Wang
Department of Pediatric Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.|Tumor Initiation and Maintenance, Sanford Burnham Medical Research Institute, La Jolla, CA, USA.
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Deshpande
Department of Pediatric Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.|Human Oncology and Pathogenesis Program and Department of Pediatrics, Memorial Sloan-Kettering Cancer Institute, New York, NY, USA.
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Armstrong
Department of Internal Medicine III, University of Ulm, Ulm, Baden-Württemberg, Germany.
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Döhner
Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Saxony-Anhalt, Germany.
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Fischer
Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Saxony-Anhalt, Germany.
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Heidel
D000595:Amino Acid Sequence; D000818:Animals; D049109:Cell Proliferation; D004305:Dose-Response Relationship, Drug; D006801:Humans; D066298:In Vitro Techniques; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D009154:Mutation; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors*; D051941:fms-Like Tyrosine Kinase 3 / Q000235:genetics*
D047428:Protein Kinase Inhibitors; C497970:FLT3 protein, human; D011505:Protein-Tyrosine Kinases; D051941:fms-Like Tyrosine Kinase 3