Subcutaneous Infection Associated with Trichosporon ovoides: A Case Report and Review of Literature.
Trichosporon species are opportunistic yeasts which can cause infections, especially in immunocompromised patients. This is a report of Trichosporon ovoides that caused subcutaneous infection in a patient with underlying ischemic heart disease. The identification of fungal isolate was confirmed by PCR sequencing of ITS and large subunit regions in rRNA gene. In vitro susceptibility study showed that the isolate was susceptible to amphotericin B, fluconazole and voriconazole, and resistant to caspofungin, anidulafungin and itraconazole. The lesion improved after treatment with oral fluconazole and topical miconazole.
Bacteriology Unit, Infectious Diseases Research Center, Institute for Medical Research, Jalan Pahang, 50588, Kuala Lumpur, Malaysia. ratna@imr.gov.my.
Ratna
R
Mohd Tap
Bacteriology Unit, Infectious Diseases Research Center, Institute for Medical Research, Jalan Pahang, 50588, Kuala Lumpur, Malaysia.
Parameswari
P
Sabaratnam
Bacteriology Unit, Infectious Diseases Research Center, Institute for Medical Research, Jalan Pahang, 50588, Kuala Lumpur, Malaysia.
Nur Yasmin
NY
Ramli
Bacteriology Unit, Infectious Diseases Research Center, Institute for Medical Research, Jalan Pahang, 50588, Kuala Lumpur, Malaysia.
Rohaidah
R
Hashim
Bacteriology Unit, Infectious Diseases Research Center, Institute for Medical Research, Jalan Pahang, 50588, Kuala Lumpur, Malaysia.
Abd Razak
AR
Mohd Fuat
Microbiology Unit, Pathology Department, Sultanah Bahiyah Hospital, Alor Setar, Kedah, Malaysia.
Pey Peng
PP
Ng
Microbiology Unit, Pathology Department, Sultanah Bahiyah Hospital, Alor Setar, Kedah, Malaysia.
Husna
H
Khairam
Bacteriology Unit, Infectious Diseases Research Center, Institute for Medical Research, Jalan Pahang, 50588, Kuala Lumpur, Malaysia.
Norazah
N
Ahmad
D000935:Antifungal Agents / Q000627:therapeutic use*; D021901:DNA, Intergenic / Q000235:genetics; D003881:Dermatomycoses / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D008825:Miconazole / Q000627:therapeutic use; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009894:Opportunistic Infections / Q000188:drug therapy* / Q000382:microbiology; D016133:Polymerase Chain Reaction; D014250:Trichosporon / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D060586:Trichosporonosis / Q000188:drug therapy* / Q000382:microbiology
D000935:Antifungal Agents; D021901:DNA, Intergenic; D008825:Miconazole; D015725:Fluconazole
Subcutaneous infection; Trichosporon ovoides; Trichosporonosis