Digital phantoms generated by spectral and spatial light modulators.
A hyperspectral image projector (HIP) based on liquid crystal on silicon spatial light modulators is explained and demonstrated to generate data cubes. The HIP-constructed data cubes are three-dimensional images of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxyhemoglobin molecules in single erythrocytes. Spectrally and spatially resolved image data indistinguishable from the real scene may be used as standard data cubes, so-called digital phantoms, to calibrate image sensors and validate image analysis algorithms for their measurement quality, performance consistency, and interlaboratory comparisons for quantitative biomedical imaging applications.
National Institute of Standards and Technology, Quantum Electronics and Photonics Division, 325 Broadway Street, Boulder, Colorado 80305, United States.
Bonghwan
B
Chon
National Institutes of Health, Laboratory of Malaria and Vector Research, 9000 Rockville Pike, Bethesda, Maryland 20892, United States.
Fuyuki
F
Tokumasu
National Institute of Standards and Technology, Quantum Electronics and Photonics Division, 325 Broadway Street, Boulder, Colorado 80305, United States.
Ji Youn
JY
Lee
National Institute of Standards and Technology, Sensor Science Division, 100 Bureau Drive, Gaithersburg, Maryland 20899, United States.
David W
DW
Allen
National Institute of Standards and Technology, Sensor Science Division, 100 Bureau Drive, Gaithersburg, Maryland 20899, United States.
Joseph P
JP
Rice
National Institute of Standards and Technology, Quantum Electronics and Photonics Division, 325 Broadway Street, Boulder, Colorado 80305, United States.
Jeeseong
J
Hwang