Ancient mitochondrial genome reveals trace of prehistoric migration in the east Pamir by pastoralists.
The complete mitochondrial genome of one 700-year-old individual found in Tashkurgan, Xinjiang was target enriched and sequenced in order to shed light on the population history of Tashkurgan and determine the phylogenetic relationship of haplogroup U5a. The ancient sample was assigned to a subclade of haplogroup U5a2a1, which is defined by two rare and stable transversions at 16114A and 13928C. Phylogenetic analysis shows a distribution pattern for U5a2a that is indicative of an origin in the Volga-Ural region and exhibits a clear eastward geographical expansion that correlates with the pastoral culture also entering the Eurasian steppe. The haplogroup U5a2a present in the ancient Tashkurgan individual reveals prehistoric migration in the East Pamir by pastoralists. This study shows that studying an ancient mitochondrial genome is a useful approach for studying the evolutionary process and population history of Eastern Pamir.
School of Life Sciences, Jilin University, Changchun, China.|Research Center for Chinese Frontier Archaeology, Jilin University, Changchun, China.
Chao
C
Ning
College of Pharmacia Sciences, Jilin University, Changchun, China.
Shizhu
S
Gao
School of Life Sciences, Jilin University, Changchun, China.
Boping
B
Deng
Ministry of Education Key Laboratory of Contemporary Anthropology and State Key Laboratory of Genetic Engineering, Fudan University, Shanghai, China.
Hongxiang
H
Zheng
Research Center for Chinese Frontier Archaeology, Jilin University, Changchun, China.
Dong
D
Wei
School of Life Sciences, Jilin University, Changchun, China.|School of Clinical Medicine, Jilin University, Changchun, China.
Haoze
H
Lv
School of Life Sciences, Jilin University, Changchun, China.|Research Center for Chinese Frontier Archaeology, Jilin University, Changchun, China.
Hongjie
H
Li
School of Life Sciences, Jilin University, Changchun, China.
Li
L
Song
Xinjiang Cultural Relics and Archaeology Institute, Ürümchi, China.
Yong
Y
Wu
School of Life Sciences, Jilin University, Changchun, China.|Research Center for Chinese Frontier Archaeology, Jilin University, Changchun, China.
Hui
H
Zhou
School of Life Sciences, Jilin University, Changchun, China.|Research Center for Chinese Frontier Archaeology, Jilin University, Changchun, China.
Yinqiu
Y
Cui
D002681:China; D000072441:DNA, Ancient / Q000737:chemistry; D054629:Genome, Mitochondrial; D049691:History, Medieval; D063426:Human Migration / Q000266:history*; D006801:Humans; D010802:Phylogeny; D017422:Sequence Analysis, DNA
D000072441:DNA, Ancient