[Bilateral scleritis and extra-ocular inflammation in a patient with undiagnosed chronic lymphatic leukaemia].
A 55-year-old healthy man presented with redness and pain in both eyes and was diagnosed with bilateral scleritis. A year later impairment of ocular movement and cervical adenopathy appeared. Laboratory tests revealed signs of inflammation: increased erythrocyte sedimentation rate, lymphocytosis, lactate dehydrogenase, S-ACE converting enzyme and interleukin-2-antibody. An orbital MR-scan revealed inflammation of the extra-ocular muscles. PET-CT showed vascular changes consistent with vasculitis. Lymph node biopsy confirmed the diagnosis chronic lymphatic leukaemia (CLL). This is a rare case - presentation of bilateral scleritis in a patient with undiagnosed CLL, increased inflammatory markers and vasculitis - a possible ocular manifestation of a paraneoplastic syndrome.
Jakob Schüllhammer
JS
Knudsen
Kristian
K
Aasbjerg
Signe Schüllhammer
SS
Knudsen
davm@rn.dk.
Danson
D
Muttuvelu
D057210:Delayed Diagnosis; D005128:Eye Diseases / Q000209:etiology / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000473:pathology; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D015423:Scleritis / Q000209:etiology / Q000473:pathology