Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome.
BACKGROUND
Idiopathic Pulmonary Hemosiderosis (IPH) is a rare cause of alveolar hemorrhage, which is seen primarily in childhood. Celiac disease is defined as a chronic, immune-mediated enteropathy of the small intestine, caused by exposure to dietary gluten in genetically pre-disposed individuals. Association of IPH and celiac disease is known as Lane Hamilton syndrome. There are limited number of case reports of this syndrome in literature.


METHODS
Although there were no growth and developmental delay and gastrointestinal symptoms like chronic diarrhea, chronic constipation, vomiting, abdominal bloating and pain in the two patients with IPH, they were diagnosed with Lane Hamilton Syndrome. After initiation of gluten-free diet, their IPH symptoms disappeared and hemoglobin levels were observed to return to normal.


CONCLUSIONS
Even if there were no gastrointestinal symptoms in a patient with IPH, celiac disease should be investigated. These patients may benefit from gluten free diet and IPH symptoms may disappear.
Department of Pediatric Allergy, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
Hikmet Tekin
HT
Nacaroglu
Department of Pediatric Allergy, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
Ozlem Sarac
OS
Sandal
Clinics of Pediatrics, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
Ozlem
O
Bag
Department of Pediatric Allergy, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
Semiha Bahceci
SB
Erdem
Department of Pediatric Gastroenterology, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
Ozlem
O
Bekem Soylu
Department of Pathology, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
Gulden
G
Diniz
Clinics of Pediatrics, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
Aysel
A
Ozturk
Department of Pediatric Allergy, Dr. Behcet Uz Children's Hospital, Izmir, Turkey.
Demet
D
Can
Celiac Disease; Gluten-Free Diet; Idiopathic Pulmonary Hemosiderosis; Lane-Hamilton Syndrome