Challenges of Clinical Research on Hepatocellular Carcinoma.
Challenges of clinical practice and research on hepatocellular carcinoma (HCC) were reviewed. There are several differences in clinical practice between Japan and the Western countries such as tumor markers, understanding of pathological early HCC, imaging diagnosis, treatment strategy, staging system and subclassification of HCC. Further studies are warranted for the clinical practices of Japan to be adopted in the rest of the world.
Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Osaka-Sayama, Osaka, Japan.
Masatoshi
M
Kudo
Masayuki
M
Kitano
Toshiharu
T
Sakurai
Naoshi
N
Nishida
D000465:Algorithms; D014408:Biomarkers, Tumor / Q000032:analysis; D035843:Biomedical Research; D006528:Carcinoma, Hepatocellular / Q000145:classification / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D007564:Japan; D008113:Liver Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000628:therapy*; D011379:Prognosis; D019366:Western World
D014408:Biomarkers, Tumor