[LEFT VENTRICULAR MYOCARDIAL REMODELING IN PATIENTS WITH ARTERIAL HYPERTENSION ASSOCIATED WITH ACID-DEPENDENT DISEASES].
Comorbid pathologies remain a serious challenge for researchers and practitioners. According to different authors, from 11.6 to 50% therapeutic patients suffer arterial hypertension (AH) concomitant with acid-dependent diseases (ADD). Peculiarities of such combination are poorly known. The aim of this work was to evaluate the structural and functional status of left ventricular (LV) myocardium in patients with AH and ADD. It included 127 patients of mean age 42.44:2.78 years. Control group consisted of 25 age-matched patients with isolated AH. The ultrasound study of structural and functional parameters of LV myocardium was followed by the analysis of various types of its remodeling. It was shown that patients with isolated AH are characterized by significantly higher structural and functional parameters of LV myocardium remodeling compared with the patients having AH and concomitant ADD. It suggests a specific type of remodeling in the former group that can be used as a predictor of higher cardiovascular risk in these patients.
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Beresneva
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Khlynova
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LM
Vasilets
D000328:Adult; D015897:Comorbidity; D005260:Female; D005744:Gastric Acid; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D013272:Stomach Diseases / Q000453:epidemiology*; D020257:Ventricular Remodeling / Q000502:physiology*