Association of Torsion With Testicular Cancer: A Retrospective Study.
Testicular torsion is a medical emergency that usually requires surgical exploration. However, testicular malignancy has been anecdotally reported with the association of torsion in surgical specimens, and the published data remain scant on the association of torsion with testicular tumors. By retrospective medical record review, we identified 32 patients who had been diagnosed with testicular torsion, 20 of whom had undergone orchiectomy. Of these 20 patients, 2 were diagnosed with a malignancy. Our study, the largest case series to date, has shown an association between testicular torsion and testicular cancer of 6.4%.


BACKGROUND
Testicular torsion is a medical emergency that usually requires surgical exploration. However, testicular malignancy has been anecdotally reported in association with torsion in surgical specimens. However, the published data remain scant on the association between torsion and the presence of testicular tumors. The present retrospective study explored the association between torsion and testicular cancer in patients with testicular torsion undergoing orchiectomy during scrotal exploration.


METHODS
A medical record review was performed of patients who had had a diagnosis of testicular torsion from January 2003 to February 2015. The clinicopathologic characteristics of the patients were recorded.


RESULTS
A total of 32 patients were identified. Their mean age was 21.1 years (range, 7-39 years). All the patients had unilateral testicular torsion, which affected the left side in 17 and the right side in 15. Manual detorsion was successful in 6 patients, and 26 patients underwent emergency surgery with testicular detorsion (6 fixation surgery and 20 orchiectomy). The type of incision was scrotal in 6, inguinal in 10, and unspecified in 4. Pathologic examination of the orchiectomy specimens showed malignancy in 2 cases (seminoma and malign mixed germ cell tumor).


CONCLUSIONS
To the best of our knowledge, the present single-center case series is the largest case series to date of testicular torsion and showed an association between testicular torsion and testicular cancer of 6.4%. However, further larger series of the association between testicular torsion and cancer are needed to explore the relationship between testicular torsion and testicular cancer.
Department of Urology, Gulhane Military Medical Academy, Ankara, Turkey.
Sami
S
Uguz
Department of Urology, Gulhane Military Medical Academy, Ankara, Turkey. Electronic address: drsercanyilmaz@gmail.com.
Sercan
S
Yilmaz
Department of Urology, Gulhane Military Medical Academy, Ankara, Turkey.
Ali
A
Guragac
Department of Urology, Gulhane Military Medical Academy, Ankara, Turkey.
Bahadır
B
Topuz
Department of Urology, Gulhane Military Medical Academy, Ankara, Turkey.
Emin
E
Aydur
D000293:Adolescent; D000328:Adult; D002648:Child; D006801:Humans; D033162:Incidental Findings; D008297:Male; D009919:Orchiectomy; D012189:Retrospective Studies; D018239:Seminoma / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D013086:Spermatic Cord Torsion / Q000453:epidemiology / Q000601:surgery*; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D055815:Young Adult
Malign mixed germ cell tumor; Orchiectomy; Seminoma; Testicular malignancy; Testicular pain