Relationship between weight gain and metabolic syndrome in non-obese Japanese adults.
OBJECTIVE
To examine the effects of weight gain (in kg) on the parameters of metabolic syndrome (MetS) in non-obese Japanese adults over a period of 1 year.


METHODS
We analyzed data on 1653 workers in a financial corporation (698 males and 955 females) who may have gained weight during 1 year but nevertheless remained non-obese. Data were collected twice: baseline data were collected between April 2010 and March 2011, and follow-up data were collected the next year. We calculated weight gains over the year and assigned all subjects into one of four groups according to the amount of weight gained: 0-0.99kg weight gain (reference), 1.00-1.99kg, 2.00-2.99kg, and more than 3.00kg. We compared changes in MetS parameters between the reference and other groups using Analysis of covariance (ANCOVA).


RESULTS
Significant between-group differences were evident among males in terms of abdominal circumference (AC), blood pressure, and triglyceride (TG) levels. More weight gain was associated with worse results with regard to these MetS parameters. The AC changes were 0.60, 1.55, 2.86, and 4.42cm in the reference group, those who gained 1.00-1.99kg, those who gained 2.00-2.99kg, and those who gained over 3.00kg, respectively; the differences between the reference group and all other groups were significant (all p values <0.001).


CONCLUSIONS
Weight gain (in kg) is a useful index of weight change and influences several parameters of MetS even over the course of 1 year.
Graduate School of Humanities and Sciences, Ochanomizu University, c/o Rie Akamatau, 2-1-1, Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan.
Shiori
S
Toga
Graduate School of Humanities and Sciences, Ochanomizu University, c/o Rie Akamatau, 2-1-1, Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan.
Yuko
Y
Fukkoshi
Natural Science Division, Faculty of Core Research, Ochanomizu University, 2-1-1, Otsuka, Bunkyo-ku, Tokyo 112-8610, Japan. Electronic address: akamatsu.rie@ocha.ac.jp.
Rie
R
Akamatsu
D000328:Adult; D001794:Blood Pressure; D005260:Female; D006801:Humans; D007564:Japan; D008137:Longitudinal Studies; D008297:Male; D024821:Metabolic Syndrome / Q000473:pathology*; D012307:Risk Factors; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference; D015430:Weight Gain
D014280:Triglycerides
Adults; Japanese; Metabolic syndrome X; Non-obese; Wight gain