First report of New Delhi metallo-β-lactamase 5 (NDM-5)-producing Escherichia coli from blood cultures of three leukemia patients.
We report the first occurrence of New Delhi metallo-β-lactamase 5 (NDM-5) in carbapenem-resistant Escherichia coli isolated from blood cultures of three leukemia patients in northern China. These patients had at some time been hospitalized in the hematology department of the same hospital. All isolates were ST167 with identical pulsed-field gel electrophoresis patterns, suggesting a likely hospital transmission.
Postgraduate Training Base of General Hospital of Shenyang Military Command, Liaoning Medical University, Jinzhou, China.
Li-Ping
LP
Zhang
Clinical Laboratory, General Hospital of Shenyang Military Command, Shenyang, China.
Wen-Cheng
WC
Xue
Clinical Laboratory, General Hospital of Shenyang Military Command, Shenyang, China. Electronic address: 13309889399@189.cn.
Dong-Ya
DY
Meng
D000328:Adult; D016470:Bacteremia / Q000382:microbiology*; D015780:Carbapenems / Q000494:pharmacology; D002681:China; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology*; D006801:Humans; D007938:Leukemia / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D001618:beta-Lactamases / Q000096:biosynthesis*
D015780:Carbapenems; D001618:beta-Lactamases
Carbapenem-resistant; Escherichia coli; Multilocus sequence typing (MLST); New Delhi metallo-β-lactamase 5 (NDM-5); Pulsed-field gel electrophoresis (PFGE)