Synchronous Pulmonary Malignancies: Atypical Presentation of Mantle Cell Lymphoma Masking a Lung Malignancy.
We present a case of a pleural space malignancy masked by an atypical presentation of mantle cell lymphoma. Our patient presented with a large pleural effusion and right sided pleural studding, initially attributed to a new diagnosis of mantle cell lymphoma. Rare atypical epithelial cells were also seen amongst the clonal population of lymphocytes. The patient lacked systemic manifestations of mantle cell lymphoma and did not improve with chemotherapy. A pleural biopsy ultimately revealed the presence of an undifferentiated carcinoma, favoring a lung primary. A discussion of synchronous pleural space malignancies involving lymphomas is given.
Department of Internal Medicine, Boston University , MA, USA.
Luke
L
Masha
Section of Pulmonary and Critical Care Medicine, Yale New Haven Hospital , New Haven, CT, USA.
Andrey
A
Zinchuk
Section of Hematology/Oncology, Boston VA Healthcare System , MA, USA.
Valia
V
Boosalis
Lymphoma; lung cancer; mantle cell; pleural effusion