[Fluorescein angiography and optical coherence tomography findings in central fundus of myopic patients].
Myopia prevalence grows alike in many countries, including Russia, regardless of geographical and population conditions.


OBJECTIVE
to assess fundus changes in myopic patients at different ocular axial lengths by means of modern diagnostic tools.


METHODS
The study enrolled 97 patients (194 eyes) aged 45 ± 20.17 years with myopia of different degrees. Besides a standard ophthalmic examination, all patients underwent fundus fluorescein angiography and optical coherence tomography.


RESULTS
The occurrence of retinal pigment epithelium (RPE) atrophy (diffuse or focal) has been shown to increase with increasing ocular axial length. Only 27 eyes (28.1%) appeared intact. As myopia progression implies axial growth of the eye, it is associated with a more severe decrease in choroid, RPE, and photoreceptor layer thicknesses: the longer the anterior-posterior axis, the thinner the above mentioned fundus structures. Age-related changes in the fundus are also likely to be more pronounced in longer axes. Myopic traction maculopathy, which in our case appeared the main cause of increased retinal thickness, was diagnosed in 105 eyes, "outer" macular retinoschisis--in 40 eyes.


CONCLUSIONS
Thus, modern diagnostic tools, such as fluorescein angiography and optical coherence tomography, enable objective assessment of the central fundus.
Research Institute of Eye Diseases, 11 A,B Rossolimo St., Moscow, Russian Federation, 119021; I.M. Sechenov First Moscow State Medical University, 8-2 Trubetskaya St., Moscow, Russian Federation, 119048.
S E
SE
Avetisov
Research Institute of Eye Diseases, 11 A,B Rossolimo St., Moscow, Russian Federation, 119021.
M V
MV
Budzinskaya
Research Institute of Eye Diseases, 11 A,B Rossolimo St., Moscow, Russian Federation, 119021.
O A
OA
Zhabina
Research Institute of Eye Diseases, 11 A,B Rossolimo St., Moscow, Russian Federation, 119021.
I V
IV
Andreeva
Research Institute of Eye Diseases, 11 A,B Rossolimo St., Moscow, Russian Federation, 119021.
A A
AA
Plyukhova
I.M. Sechenov First Moscow State Medical University, 8-2 Trubetskaya St., Moscow, Russian Federation, 119048.
M V
MV
Kobzova
I.M. Sechenov First Moscow State Medical University, 8-2 Trubetskaya St., Moscow, Russian Federation, 119048.
G M
GM
Musaeva
D000328:Adult; D000367:Age Factors; D000368:Aged; D001284:Atrophy; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000175:diagnosis / Q000503:physiopathology; D015203:Reproducibility of Results; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence / Q000379:methods*