Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants.
The nanocrystals of a porphyrin-based zirconium(IV) metal-organic framework (MOF) are used as a dual-function catalyst for the simultaneous detoxification of two chemical warfare agent simulants at room temperature. Simulants of nerve agent (such as GD, VX) and mustard gas, dimethyl 4-nitrophenyl phosphate and 2-chloroethyl ethyl sulfide, have been hydrolyzed and oxidized, respectively, to nontoxic products via a pair of pathways catalyzed by the same MOF. Phosphotriesterase-like activity of the Zr6-containing node combined with photoactivity of the porphyrin linker gives rise to a versatile MOF catalyst. In addition, bringing the MOF crystals down to the nanoregime leads to acceleration of the catalysis.
Department of Chemistry, Northwestern University , 2145 Sheridan Road, Evanston, Illinois 60208, United States.
Yangyang
Y
Liu
Department of Chemistry, Northwestern University , 2145 Sheridan Road, Evanston, Illinois 60208, United States.
Su-Young
SY
Moon
Department of Chemistry, Northwestern University , 2145 Sheridan Road, Evanston, Illinois 60208, United States.
Joseph T
JT
Hupp
Department of Chemistry, Northwestern University , 2145 Sheridan Road, Evanston, Illinois 60208, United States.|Department of Chemistry, Faculty of Science, King Abdulaziz University , Jeddah 22254, Saudi Arabia.
Omar K
OK
Farha
D002384:Catalysis; D002619:Chemical Warfare Agents / Q000032:analysis / Q000737:chemistry*; D007700:Kinetics; D036103:Nanotechnology / Q000379:methods*; D011166:Porphyrins / Q000737:chemistry*; D015040:Zirconium / Q000737:chemistry*
D002619:Chemical Warfare Agents; D011166:Porphyrins; D015040:Zirconium
CEES; DMNP; GD; Simulant; Soman; VX; chemical warfare agents; dual function; heterogeneous catalysis; metal−organic frameworks