[Exploration of the Essence of "Endogenous Turbidity" in Chinese Medicine].
The essence of endogenous turbidity in Chinese medicine (CM) is different from cream, fat, phlegm, retention, damp, toxicity, and stasis. Along with the development of modern scientific technologies and biology, researches on the essence of endogenous turbidity should keep pace with the time. Its material bases should be defined and new connotation endowed at the microscopic level. The essence of turbidity lies in abnormal functions of zang-fu organs. Sugar, fat, protein, and other nutrient substances cannot be properly decomposed, but into semi-finished products or intermediate metabolites. They are inactive and cannot participate in normal material syntheses and decomposition. They cannot be transformed to energy metabolism, but also cannot be synthesized as executive functioning of active proteins. If they cannot be degraded by autophagy-lysosome or ubiquitin-prosome into glucose, fatty acids, amino acids, and other basic nutrients to be used again, they will accumulate inside the human body and become endogenous turbidity. Therefore, endogenous turbidity is different from final metabolites such as urea, carbon dioxide, etc., which can transform vital qi. How to improve the function of zang-fu organs, enhance its degradation by autophagy-lysosome or ubiquitin-prosome is of great significance in normal operating of zang-fu organs and preventing the emergence and progress of related diseases.
Xin-rong
XR
Fan
Nong
N
Tang
Yun-xi
YX
Ji
Yao-zhong
YZ
Zhang
Li
L
Jiang
Gui-hua
GH
Huang
Sheng
S
Xie
Liu-mei
LM
Li
Chun-hui
CH
Song
Jiang-hong
JH
Ling
D001343:Autophagy; D006801:Humans; D008516:Medicine, Chinese Traditional; D046988:Proteasome Endopeptidase Complex
D046988:Proteasome Endopeptidase Complex