Micro and Macro Element Composition of Kalanchoe integra Leaves: An Adjuvant Treatment for Hypertension in Ghana.
Two samples, water extract and blended whole leaves, of fresh Kalanchoe integra leaves (Crassulaceae), a traditional antihypertensive medicine used in Ghana, were analyzed with Energy Dispersive X-Ray Fluorescence spectroscopy (EDXRF). Analysis revealed 12 macro and 26 micro elements in both extracts. Further quantitative assessment of the results for amounts of elements that are pharmacologically significant revealed that the amounts of calcium, potassium, and magnesium present in the extracts could be correlated to its traditional usage in managing hypertension and arrhythmias. However, heavy metals (lead and inorganic arsenic) detected in the extracts may pose a threat at doses normally used traditionally for the treatment of hypertension.
Department of Pharmaceutical Chemistry, UGSOP, Legon, Ghana.
S
S
Frimpong-Manso
Department of Pharmacology and Toxicology, UGSOP, Legon, Ghana.
I J
IJ
Asiedu-Gyekye
Department of Pharmaceutical Chemistry, UGSOP, Legon, Ghana.
J P
JP
Naadu
Department of Pharmaceutical Chemistry, UGSOP, Legon, Ghana.
G T
GT
Magnus-Aryitey
Department of Pharmacology and Toxicology, UGSOP, Legon, Ghana.
A K
AK
Nyarko
Geological Survey Department, Accra, Ghana.
D
D
Boamah
Geological Survey Department, Accra, Ghana.
M
M
Awan