SEOM clinical guidelines for the treatment of Hodgkin's lymphoma.
Hodgkin lymphoma (HL) is an uncommon B cell lymphoid malignancy representing approximately 10-15 % of all lymphomas. HL is composed of two distinct disease entities; the more commonly diagnosed classical HL and the rare nodular lymphocyte-predominant HL. An accurate assessment of the stage of disease and prognostic factors that identify patients at low or high risk for recurrence are used to optimize therapy. Patients with early stage disease are treated with combined modality strategies using abbreviated courses of combination chemotherapy followed by involved-field radiation therapy, while those with advanced stage disease receive a longer course of chemotherapy often without radiation therapy. High-dose chemotherapy (HDCT) followed by an autologous stem cell transplant (ASCT) is the standard of care for most patients who relapse following initial therapy. Brentuximab vedotin should be considered for patients who fail HDCT with ASCT.
Área de Oncología y Hematología, Hospital Costa del Sol, Autovía A-7, km 187, 29603, Marbella, Málaga, Spain. arueda@hcs.es.
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A
Rueda Domínguez
Servicio de Oncología Médica, Instituto Oncológico de Guipúzcoa, San Sebastian, Spain.
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J
Alfaro Lizaso
Servicio de Oncología Médica, Complejo Hospitalario Regional Virgen Macarena, Seville, Spain.
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L
de la Cruz Merino
Servicio de Oncología Médica, Hospital Universitari de Sant Joan de Reus, Reus, Spain.
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J
Gumá I Padró
Servicio de Oncología Médica, Complejo Hospitalario Regional y Virgen de la Victoria, Málaga, Spain.
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C
Quero Blanco
Servicio de Oncología Médica, Hospital Universitari i Politècnic la Fe, Valencia, Spain.
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J
Gómez Codina
Servicio de Oncología Médica, Hospital Universitario de Canarias (H.U.C), San Cristóbal De La Laguna, Tenerife, Spain.
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M
Llanos Muñoz
Servicio de Oncología Médica, Hospital General Universitario de Elche y Vega Baja, Elche, Spain.
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N
Martinez Banaclocha
Servicio de Oncología Médica, Hospital Universitario Insular de Gran Canaria, Las Palmas De Gran Canarias, Spain.
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Rodriguez Abreu
Servicio de Oncología Médica, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
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M
Provencio Pulla
D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D019468:Disease Management; D055088:Early Detection of Cancer; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008495:Medical Oncology; D009367:Neoplasm Staging; D017410:Practice Guidelines as Topic / Q000592:standards*; D011379:Prognosis; D012955:Societies, Medical
Hodgkin lymphoma; Hodgkin lymphoma therapy; Oncohematology malignancies