[Chemical Constituents from Melissa officinalis Leaves].
OBJECTIVE
To investigate the chemical constituents of Melissa officinalis leaves.


METHODS
The chemical constituents were separated by silica gel column chromatography and their structures were determined by spectroscopic experiments.


RESULTS
13 compounds were isolated and identified as protocatechuyl aldehyde(1), serratagenic acid(2), vanillin(3), 2α,3β-dihydroxy-urs-12-en-28-oic acid(4), ursolic acid(5), oleanolic acid(6), daucosterol(7),2α,3β,23,29-tetrahydroxyolean-12-en-28-oic acid-29-O-β-D-gluco- pyranoside(8), luteolin(9) rosmarinic acid(10), luteolin-7-O-β-D-glucoside (11), β-stitosterol(12) and palmitic acid(13).


CONCLUSIONS
Compounds 1 ~ 8 are separated from this plant for the first time and compounds 1-4 and 8 are isolated from this genus for the first time.
Zi-yang
ZY
Ji
Yan-xia
YX
Yang
Fang-fang
FF
Zhuang
Fu-lin
FL
Yan
Chang-hong
CH
Wang
D001547:Benzaldehydes; D002934:Cinnamates; D053630:Depsides; D031334:Melissa / Q000737:chemistry*; D009828:Oleanolic Acid; D019308:Palmitic Acid; D064209:Phytochemicals / Q000737:chemistry* / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry*; D012855:Sitosterols; D014315:Triterpenes; D000097123:Rosmarinic Acid; D000097245:Ursolic Acid
D001547:Benzaldehydes; D002934:Cinnamates; D053630:Depsides; D009828:Oleanolic Acid; D019308:Palmitic Acid; D064209:Phytochemicals; D010936:Plant Extracts; D012855:Sitosterols; D014315:Triterpenes; D000097123:Rosmarinic Acid; D000097245:Ursolic Acid; C025473:gamma-sitosterol; C064859:serratagenic acid; C100058:vanillin; C011015:lyoniside