[A Case of Esophageal Cancer in a Patient with CMV Reactivation after Neoadjuvant Chemoradiation Therapy].
A 68-year-old woman was diagnosed with advanced esophageal cancer with lymph node metastasis, for which she received neoadjuvant chemoradiotherapy. During therapy, she had loss of appetite and weight; therefore, we inserted a nasal feeding tube for her nutrition, after which, she gained weight soon. After therapy, she had a high fever with lymphocytopenia and was diagnosed with cytomegalovirus infection because of significantly high CMV antigenemia. Ganciclovir was administered immediately, and she recovered soon. Two months later, we performed esophagectomy, and she recovered without complications. Immediate diagnosis of CMV infection, ganciclovir administration, and nutrition through a feeding tube were useful for the esophageal cancer patient in this report who had immunosuppression and malnutrition during chemoradiation.
Dept. of Digestive Surgery, Breast and Thyroid Surgery.
Koichi
K
Megumi
Hiroshi
H
Okumura
Masataka
M
Shimonosono
Tetsuya
T
Ijichi
Yasuto
Y
Uchikado
Itaru
I
Omoto
Hiroyoshi
H
Yo
Yoshiaki
Y
Kita
Yoshikazu
Y
Uenosono
Takaaki
T
Arigami
Shinichiro
S
Mori
Kenji
K
Baba
Sumiya
S
Ishigami
Tetsuhiro
T
Owaki
Shoji
S
Natsugoe
D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use; D059248:Chemoradiotherapy / Q000009:adverse effects; D003587:Cytomegalovirus / Q000502:physiology*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000188:drug therapy*; D004938:Esophageal Neoplasms / Q000473:pathology / Q000628:therapy* / Q000821:virology; D016629:Esophagectomy; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D008207:Lymphatic Metastasis; D016896:Treatment Outcome; D014775:Virus Activation
D000998:Antiviral Agents; D015774:Ganciclovir