[THE ROLE OF VEGETATIVE DYSREGULATION IN THE FORMING OF BRONCHIAL ASTHMA IN CHILDREN].
To study the heart rate variability (HRV) in bronchial asthma (BA) examined 107 children aged 10 to 18 years old with asthma exacerbation. As a result of the application of asthma control test (GINA, 2011) on the level of controlled asthma children were distributed as follows: 34 (31.8%)--with controlled (CBA), 47 (43.9%)--is partly controlled (PCBA) and 26 (24.3%)--with uncontrolled asthma (UCBA). The control group consisted of 10 healthy children of similar age. All investigated HRV measured on the device "KardyLab BCC" (Kharkov, 2009) with holding orthostatic test to assess the type of autonomic regulation, changes in autonomic balance and adaptive reserves. Analyzed time (SDNN, IN, IWT) and spectral (TP, HF, LF, VLF, LF/HF) HRV indices. Investigation of heart rate variability in children with different degrees of severity of asthma indicated presence of autonomic dysfunction syndrome. It is shown that changes in the autonomic nervous system patients differ depending on the degree controlled asthma. Thus, in children with CBA tendency to sympathicotonia in patients with UCBA often reveals signs of parasympathetic and autonomic imbalance. Severe asthma accompaniedby signs. of autonomic dysfunction: increase vagotonia, the reaction to stress and'rapid depletion of compensatory mechanisms in the restoration of homeostasis against parasympathetic dominance.
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D000222:Adaptation, Physiological; D000293:Adolescent; D001249:Asthma / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D001341:Autonomic Nervous System / Q000503:physiopathology*; D001342:Autonomic Nervous System Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D016022:Case-Control Studies; D002648:Child; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D012720:Severity of Illness Index