Opinion of the Scientific Committee on Consumer Safety (SCCS)--Opinion on the safety of the use of β-arbutin in cosmetic products.
The SCCS considers the use of β-arbutin to be safe for consumers in cosmetic products in a concentration up to 7% in face creams provided that the contamination of hydroquinone in the cosmetic formulations remain below 1 ppm. A potential combined use of β-arbutin and other hydroquinone releasing substances in cosmetic products has not been evaluated in this Opinion.
SCCS Secretariat at the European Commission, Directorate General for Health and Food Safety, 11, rue E. Ruppert, L-2920 Luxembourg, Luxembourg. Electronic address: SANTE-C2-SCCS@ec.europa.eu.
Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany.
Gisela H
GH
Degen
D000279:Administration, Cutaneous; D000818:Animals; D001104:Arbutin / Q000008:administration & dosage / Q000009:adverse effects*; D003257:Consumer Product Safety / Q000592:standards*; D003358:Cosmetics / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D006873:Hydroquinones / Q000008:administration & dosage / Q000009:adverse effects; D018570:Risk Assessment; D012307:Risk Factors
D003358:Cosmetics; D006873:Hydroquinones; D001104:Arbutin; C031927:hydroquinone
CAS: 497-76-7; EC: 207-850-3; Regulation 1223/2009; SCCS; Scientific opinion; β-arbutin