Conduction abnormalities during dipyridamole stress testing.
Pharmacological stress tests using dipyridamole are considered to be safe. However, cases of atrioventricular (AV) block have been reported. We retrospectively analyzed ECG at baseline and during dipyridamole stress tests of 2010 consecutive patients (patients with second or third degree AV block were excluded). At baseline, 350 (17.4%) patients had conduction abnormalities. Following dipyridamole infusion 16 patients (0.8%) developed a transient change in AV conduction (15 patients) and or sinus arrest (1 patient). Compared to patients without baseline conduction abnormalities, patients with any conduction abnormalities at baseline were at a higher risk for the development of AV block after dipyridamole infusion [0.3% vs 3.14%, respectively; P < .0001].
Department of Cardiology, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, 31096, Haifa, Israel.|Department of Nuclear medicine, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Samia
S
Massalha
Department of Nuclear medicine, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Ilya
I
Reizberg
Department of Nuclear medicine, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Ora
O
Israel
Department of Cardiology, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, 31096, Haifa, Israel.
Michael
M
Kapeliovich
Department of Cardiology, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, 31096, Haifa, Israel.
Haitham
H
Sholy
Department of Nuclear medicine, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Amjad
A
Koskosi
Department of Nuclear medicine, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Zohar
Z
Keidar
Department of Cardiology, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, 31096, Haifa, Israel. i_marai@rambam.health.gov.il.
Ibrahim
I
Marai
D054537:Atrioventricular Block / Q000175:diagnosis / Q000453:epidemiology*; D001919:Bradycardia / Q000175:diagnosis / Q000453:epidemiology*; D015984:Causality; D015897:Comorbidity; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D004176:Dipyridamole; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology*; D005080:Exercise Test / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D007557:Israel / Q000453:epidemiology; D008297:Male; D019275:Radiopharmaceuticals; D012307:Risk Factors; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000706:statistics & numerical data; D014665:Vasodilator Agents
D019275:Radiopharmaceuticals; D014665:Vasodilator Agents; D004176:Dipyridamole; D017256:Technetium Tc 99m Sestamibi
Dipyridamole; atrioventricular block; sinus arrest