Genome-wide gene expression profiling to investigate molecular phenotypes of Arabidopsis mutants deprived in distinct histone methyltransferases and demethylases.
Histone lysine (K) methylation is a type of epigenetic modification involved in regulation of DNA-based processes, including transcription, replication and repair. It can either activate or repress transcription depending on the histone K residue on which methylation occurs and on chromatin context of additional other modifications. In both animals and plants, methylation on one histone K residue can be deposited by several different histone methyltransferases and vice versa removed by different histone demethylases. It is of great interest to know which histone enzyme regulates which genes in the genome. Here we describe in details the contents and quality controls for the gene expression data of Arabidopsis mutants deprived in distinct histone methyltransferases (SDG26, SDG25, ATX1, CLF) and histone demethylases (LDL1, LDL2), in association with the study recently published by Berr and colleagues in The Plant Journal (Berr et al., 2015). The microarray dataset has been deposited in Gene Expression Omnibus with accession number GSE55167.
Institut de Biologie Moléculaire des Plantes, UPR2357 CNRS, Université de Strasbourg, 12 rue du Général Zimmer, 67084 Strasbourg, France.
Wei
W
Zhao
Institut de Biologie Moléculaire des Plantes, UPR2357 CNRS, Université de Strasbourg, 12 rue du Général Zimmer, 67084 Strasbourg, France.
Sarfraz
S
Shafiq
Institut de Biologie Moléculaire des Plantes, UPR2357 CNRS, Université de Strasbourg, 12 rue du Général Zimmer, 67084 Strasbourg, France.
Alexandre
A
Berr
Institut de Biologie Moléculaire des Plantes, UPR2357 CNRS, Université de Strasbourg, 12 rue du Général Zimmer, 67084 Strasbourg, France.
Wen-Hui
WH
Shen
Arabidopsis; Chromatin; Histone methylation; Transcription