The effect of controlled microrobotized blasting on implant surface texturing and early osseointegration.
Surface topography modifications have become a key strategy for hastening the host-to-implant response to implantable materials. The present study evaluated the effect of three different carefully controlled surface texture patterns achieved through microrobotized blasting (controlled to high, medium and low roughness) relative to a larger scale blasting procedure (control) in early osseointegration in a canine model. Four commercially pure grade 2 titanium alloy implants (one of each surface) were bilaterally placed in the radii of six beagle dogs and allowed end points of 1 and 6 weeks in vivo. Following sacrifice, implants in bone were non-decalcified processed for bone morphologic and histometric (bone-to-implant contact; bone area fraction occupancy) evaluation. Surface topography was characterized by scanning electron microscopy and optical interferometry. Results showed initial osteogenic tissue interaction at one week and new bone in intimate contact with all implant surfaces at 6 weeks. At 1 and 6 weeks in vivo, higher bone-to-implant and bone area fraction occupancy were observed for the high texture pattern microrobotized blasted surface relative to others.
Universidade Federal de Santa Catarina, Department of Dentistry, Florianopolis, Brazil.
Luiz F
LF
Gil
UNIGRANRIO University, Postgraduate Program in Dentistry, Duque de Caxias, Brazil.
Charles
C
Marin
University of Pennsylvania, School of Dental Medicine, Department of Orthodontics, Philadelphia, PA, USA (for Dr. Hellen Teixeira).
Hellen
H
Teixeira
São Paulo State University, Department of Surgery and Integrated Clinics, Araçatuba, Brazil.
Heloisa F
HF
Marão
New York University, Department of Biomaterials and Biomimetics, New York, USA.
Nick
N
Tovar
New York University, Department of Biomaterials and Biomimetics, New York, USA.
Rehan
R
Khan
University of Sao Paulo - Bauru College of Dentistry, Department of Prosthodontics, Bauru, SP, Brazil (for Estevam A. Bonfante) estevamab@gmail.com.
Estevam A
EA
Bonfante
Department of Epidemiology and Health Promotion, New York University College of Dentistry (for Dr. Malvin Janal).
Malvin
M
Janal
University of Pennsylvania, School of Dental Medicine, Department of Orthodontics, Philadelphia, PA, USA (for Dr. Hellen Teixeira) New York University, Department of Biomaterials and Biomimetics, New York, USA Director for Implant Research, Department of Periodontology and Implant Dentistry, New York University, New York, NY, USA (For Dr. Paulo G. Coelho) Affiliated Faculty, Department of Engineering, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates. (For Dr. Paulo G. Coelho).
Paulo G
PG
Coelho
D000497:Alloys; D000818:Animals; D018786:Bone Substitutes; D001842:Bone and Bones; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D015921:Dental Implants; D004285:Dogs; D007368:Interferometry; D008297:Male; D008855:Microscopy, Electron, Scanning; D008904:Miniaturization; D055095:Optics and Photonics; D016348:Osseointegration / Q000502:physiology*; D011474:Prosthesis Design; D012371:Robotics; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry
D000497:Alloys; D018786:Bone Substitutes; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D014025:Titanium
Implant surface; bone; histology; osseointegration; surface roughness