[Stereotactic Body Radiotherapy with CyberKnife®for Liver Metastases from Colorectal Cancer].
For treatment of colorectal liver metastases, liver resection is recommended for resectable cases in the clinical guidelines for colorectal cancer. On the other hand, there are currently no data supporting the efficacy of radiation therapy as a topical treatment, and this treatment can therefore not presently be recommended. With CyberKnife®, it is possible to perform stereotactic radiation therapy using a linear accelerator with high accuracy, even for lesions in the trunk area such as liver metastases. Between December 2009 and September 2014 in our hospital, we performed radiation treatment using CyberKnife® for 14 cases with 22 colorectal liver metastases. As a result, we obtained response and local control rates of 76.2%and 81.0%, respectively. Moreover, no advanced adverse events were observed. Thus, we consider that CyberKnife® treatment for colorectal liver metastases is effective as a topical treatment, with low invasiveness and high safety.
Dept. of Surgery, Saiseikai Yokohamashi Tobu Hospital.
Koki
K
Mihara
Masaki
M
Kaihara
Sayaka
S
Sunahori
Naotsugu
N
Yamashiro
Shin
S
Nishiya
Yasuhiro
Y
Ito
Kazuto
K
Funakoshi
Tomohisa
T
Egawa
Nobuhiro
N
Tsukamoto
Atsushi
A
Nagashima
D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016634:Radiosurgery; D014057:Tomography, X-Ray Computed