ABO/Rh Blood Groups and Risk of HIV Infection and Hepatitis B Among Blood Donors of Abidjan, Côte D'ivoire.
Hepatitis B and HIV infection are two viral infections that represent real global public health problems. In order to improve their management, some hypotheses suggest that genetic predispositions like ABO and Rh blood groups would influence the occurrence of these diseases. The aim of the present study was to examine the association between ABO and Rhesus blood groups and the susceptibility to HIV infection and hepatitis B. We conducted a cross-sectional and analytical study in a population of voluntary blood donors in the Blood Transfusion Center of Abidjan. All blood donors who donated blood between January and June 2014 were tested for HBs antigen and anti-HIV antibodies (ELISA tests) and were ABO typed. The total number of examined blood donors during this period was 45,538, of which 0.32% and 8.07% were respectively infected with HIV and hepatitis B virus. O-group donors were more infected than non-O donors. Our study is an outline concerning the search for a link between ABO and Rh blood groups and hepatitis B and HIV infection. Further studies should be conducted to confirm the interaction between these two infections and contribute to the search for new therapeutic approaches.
Immunology-Allergology Department, UFR Medical Sciences, Felix Houphouet Boigny University , Abidjan, Côte d'Ivoire.
Liliane Kouabla
LK
Siransy
Faculty of Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University , Abidjan, Côte d'Ivoire ; National Public Health Laboratory , Abidjan, Côte d'Ivoire.
Zizendorf Yves
ZY
Nanga
Bacteriology-Virology Department, Central Laboratory of the University Hospital of Yopougon , Côte d'Ivoire.
Flore Sandrine
FS
Zaba
Laboratory of Microbiology - CNR/HIV, University Hospital Sylvanus Olympio , Togo.
Nyasenu Yawo
NY
Tufa
Immunology-Allergology Department, UFR Medical Sciences, Felix Houphouet Boigny University , Abidjan, Côte d'Ivoire.
Sery Romuald
SR
Dasse
ABO blood group; Côte d’Ivoire; HIV infection; Rh blood groups; blood donors; hepatitis B