Preparation of γ-aminopropyltriethoxysilane cross-linked poly(aspartic acid) superabsorbent hydrogels without organic solvent.
Poly(aspartic acid) (PASP) hydrogel is a type of biodegradable and biocompatible polymer with high water absorbing ability. Traditionally, the production of PASP hydrogel is expensive, complex, environmentally unfriendly, and consumes a large amount of organic solvents, e.g. dimethylformamide or dimethylsulfoxide. This study introduces a one-step synthesis of PASP resin, in which the organic phase was replaced by distilled water and γ-aminopropyltriethoxysilane was used as the cross-linker. Absorbent ability and characteristics were determined by swelling ratio, FTIR, (13)C SSNMR, and SEM. In vitro cytotoxicity evaluation and animal skin irritation tests showed the hydrogel has body-friendly properties. Preparing PASP hydrogel in aqueous solution is promising and finds its use in many applications.
a Beijing Key Laboratory of Bioprocess , College of Life Science and Technology, Beijing University of Chemical Technology , Beijing , China.
Hongyu
H
Meng
a Beijing Key Laboratory of Bioprocess , College of Life Science and Technology, Beijing University of Chemical Technology , Beijing , China.
Xin
X
Zhang
a Beijing Key Laboratory of Bioprocess , College of Life Science and Technology, Beijing University of Chemical Technology , Beijing , China.
Shenyu
S
Sun
a Beijing Key Laboratory of Bioprocess , College of Life Science and Technology, Beijing University of Chemical Technology , Beijing , China.
Tianwei
T
Tan
a Beijing Key Laboratory of Bioprocess , College of Life Science and Technology, Beijing University of Chemical Technology , Beijing , China.
Hui
H
Cao
D065966:Absorption, Physicochemical; D000818:Animals; D002460:Cell Line; D020100:Hydrogels / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry* / Q000633:toxicity; D011312:Pressure; D011437:Propylamines; D011817:Rabbits; D012821:Silanes / Q000737:chemistry*; D023422:Skin Irritancy Tests; D012972:Sodium Hydroxide / Q000737:chemistry; D014867:Water / Q000737:chemistry
D020100:Hydrogels; D010455:Peptides; D011437:Propylamines; D012821:Silanes; D014867:Water; C017645:polyaspartate; D012972:Sodium Hydroxide; C477625:amino-propyl-triethoxysilane
Poly(aspartic acid); organic solution free; superabsorbent; synthesis; γ-aminopropyltriethoxysilane