SPOP the mutation.
Prostate cancers with mutations to a protein called SPOP use an error-prone method to repair broken DNA strands.
Department of Pharmacology and Molecular Sciences, University of Colorado, Aurora, United States.
Leah
L
Rider
Department of Pharmacology, University of Colorado, Aurora, United States.
Scott D
SD
Cramer
D000818:Animals; D042822:Genomic Instability; D006801:Humans; D008297:Male; D009687:Nuclear Proteins / Q000172:deficiency*; D011471:Prostatic Neoplasms / Q000473:pathology*; D012097:Repressor Proteins / Q000172:deficiency*
D009687:Nuclear Proteins; D012097:Repressor Proteins
DNA repair; SPOP; cancer genomics; cell biology; human; human biology; medicine; mouse; prostate cancer; zebrafish