Metabolomics to Decipher the Chemical Defense of Cereals against Fusarium graminearum and Deoxynivalenol Accumulation.
Fusarium graminearum is the causal agent of Fusarium head blight (FHB) and Gibberella ear rot (GER), two devastating diseases of wheat, barley, and maize. Furthermore, F. graminearum species can produce type B trichothecene mycotoxins that accumulate in grains. Use of FHB and GER resistant cultivars is one of the most promising strategies to reduce damage induced by F. graminearum. Combined with genetic approaches, metabolomic ones can provide powerful opportunities for plant breeding through the identification of resistant biomarker metabolites which have the advantage of integrating the genetic background and the influence of the environment. In the past decade, several metabolomics attempts have been made to decipher the chemical defense that cereals employ to counteract F. graminearum. By covering the major classes of metabolites that have been highlighted and addressing their potential role, this review demonstrates the complex and integrated network of events that cereals can orchestrate to resist to F. graminearum.
Euralis, Domaine de Sandreau, 6 chemin de Panedeautes, Mondonville CS 60224, 31705 Blagnac Cedex, France. lea.gauthier@bordeaux.inra.fr.|INRA, UR1264 MycSA, 71 avenue Edouard Bourleaux, CS20032, 33882 Villenave d'Ornon Cedex, France. lea.gauthier@bordeaux.inra.fr.
Léa
L
Gauthier
INRA, UR1264 MycSA, 71 avenue Edouard Bourleaux, CS20032, 33882 Villenave d'Ornon Cedex, France. vatanaso@bordeaux.inra.fr.
Vessela
V
Atanasova-Penichon
INRA, UR1264 MycSA, 71 avenue Edouard Bourleaux, CS20032, 33882 Villenave d'Ornon Cedex, France. sylvain.chereau@bordeaux.inra.fr.
Sylvain
S
Chéreau
INRA, UR1264 MycSA, 71 avenue Edouard Bourleaux, CS20032, 33882 Villenave d'Ornon Cedex, France. fforget@bordeaux.inra.fr.
Florence
F
Richard-Forget
D002523:Edible Grain / Q000378:metabolism* / Q000382:microbiology*; D005670:Fusarium / Q000378:metabolism*; D055432:Metabolomics; D009183:Mycotoxins / Q000378:metabolism; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology; D014255:Trichothecenes / Q000378:metabolism*
D009183:Mycotoxins; D014255:Trichothecenes; C007262:deoxynivalenol
fatty acids derivatives; metabolites; phenylpropanoids; plant resistance; terpenoids; toxigenic fungi