Heterotopic Gastric Mucosa in the Distal Part of Esophagus in a Teenager: Case Report.
Heterotopic gastric mucosa (HGM) of the esophagus is a congenital anomaly consisting of ectopic gastric mucosa. It may be connected with disorders of the upper gastrointestinal tract, exacerbated by Helicobacter pylori. The diagnosis of HGM is confirmed via endoscopy with biopsy. Histopathology provides the definitive diagnosis by demonstrating gastric mucosa adjacent to normal esophageal mucosa. HGM located in the distal esophagus needs differentiation from Barrett's esophagus. Barrett's esophagus is a well-known premalignant injury for adenocarcinoma of the esophagus. Malignant progression of HGM occurs in a stepwise pattern, following the metaplasia-dysplasia-adenocarcinoma sequence.We present a rare case of a teenage girl with HGM located in the distal esophagus, associated with chronic gastritis and biliary duodenogastric reflux. Endoscopy combined with biopsies is a mandatory method in clinical evaluation of metaplastic and nonmetaplastic changes within HGM of the esophagus.
From the Pediatrics Department (VVL, AI, GP, MB), University of Medicine and Pharmacy "Gr. T. Popa"; Pathology Department (DM), "St Mary" Children's Emergency Hospital; and Psychiatry Department (AC), University of Medicine and Pharmacy "Gr. T. Popa," Iasi, Romania.
Vasile Valeriu
VV
Lupu
Ancuta
A
Ignat
Gabriela
G
Paduraru
Doina
D
Mihaila
Marin
M
Burlea
Anamaria
A
Ciubara
D000293:Adolescent; D002828:Choristoma / Q000473:pathology*; D004935:Esophageal Diseases / Q000473:pathology*; D005260:Female; D005753:Gastric Mucosa; D006801:Humans