Massive pneumatosis without necrosis: A case report of Clostridium perfringens sepsis in an extremely low birth weight infant.
Pneumatosis intestinalis and free intraperitoneal air on abdominal radiographs are considered pathognomonic signs of necrotizing enterocolitis (NEC). We report a unique case of late-onset fulminant sepsis due to Clostridium perfringens presenting with shock, extensive pneumatosis intestinalis and free intraperitoneal air in an extremely low birth weight infant without histopathological evidence of bowel necrosis or NEC.
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Loma Linda University, Loma Linda, CA, USA.
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Nicolau
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of California Irvine, Irvine, CA,USA.
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Bany-Mohammed
Department of Pathology and Laboratory Medicine, University of California Irvine, Irvine, CA, and University of Southern California, Los Angeles, CA, USA.
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Carpenter
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of California Irvine, Irvine, CA,USA.
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D003015:Clostridium Infections / Q000150:complications* / Q000175:diagnosis; D003016:Clostridium perfringens / Q000302:isolation & purification*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000209:etiology*; D008297:Male; D011006:Pneumatosis Cystoides Intestinalis / Q000150:complications* / Q000175:diagnosis; D018805:Sepsis / Q000175:diagnosis / Q000209:etiology*
ELBW; NEC; anaerobic; bowel; preterm; sepsis