An Unusual Bone Metastasis Mimicking SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis) Syndrome on Bone Scintigraphy.
The costosternoclavicular region is not a common bone metastasis site, and symmetrical involvement is even rarer. Increased tracer uptake in the manubrium and sternoclavicular joints usually gives the typical "bull-horn" appearance seen in SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis). Herein, we report a case of a 47-year-old woman with a history of invasive ductal carcinoma who had undergone left radical mastectomy 3 years earlier and presented with typical increased tracer uptake in the bilateral sternocostoclavicular region resembling the so-called bull horn. The final diagnosis of metastasis from breast cancer was made histopathologically following biopsy.
From the Department of Nuclear Medicine, Wuxi Second Hospital Affiliated Nanjing Medical University, Jiangsu, China.
Jianming
J
Ni
Ping
P
Tang
D020083:Acquired Hyperostosis Syndrome / Q000000981:diagnostic imaging*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008875:Middle Aged; D011877:Radionuclide Imaging