Enantioselective Addition of Diethylzinc to Aldehydes Catalyzed by Chiral O,N,O-tridentate Phenol Ligands Derived From Camphor.
Chiral O,N,O-tridentate phenol ligands bearing a camphor backbone were found to be effective chiral catalysts for the enantioselective addition of diethylzinc to aromatic aldehydes, resulting in high enantioselectivities (80-95% ee) at room temperature.
Department of Chemistry, National Chung-Hsing University, Taichung, Taiwan, R.O.C.
Dong-Sheng
DS
Lee
Department of Chemistry, National Chung-Hsing University, Taichung, Taiwan, R.O.C.
Shu-Ming
SM
Chang
Department of Chemistry, National Chung-Hsing University, Taichung, Taiwan, R.O.C.
Chun-Ying
CY
Ho
Department of Chemistry, National Chung-Hsing University, Taichung, Taiwan, R.O.C.
Ta-Jung
TJ
Lu
asymmetric catalysis; enantioselective addition; tridentate chiral ligand