[A Case of Radical Resection of Rectal Cancer with Multiple Liver and Lung Metastases after Preoperative Chemotherapy].
We report a case of radical resection of rectal cancer with multiple liver and lung metastases after preoperative chemotherapy. A 54-year-old woman presented with abdominal pain and loss of body weight due to rectal cancer with multiple liver and lung metastases. Therefore, the patient received 14 courses of bevacizumab+mFOLFOX6, and 7 courses of panitumumab+FOLFIRI. After the chemotherapy, the size of the distant metastases reduced by 62% on computed tomography, according to RECIST. Due to the reduction in size, a conversion surgery was attempted. First, an abdominal operation with laparoscopy was performed, and 2 months later an operation to resect the lung metastases via thoracoscopy was performed. Currently, 3 months after surgery, the patient is alive, without recurrence.
Dept. of Surgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center.
Shinya
S
Yamashita
Yosuke
Y
Shimizu
Harumi
H
Tominaga
Yuri
Y
Kimura
Kazuki
K
Odagiri
Tomoaki
T
Kurokawa
Megumi
M
Yamaguchi
Gen
G
Takahashi
Genta
G
Sawada
JeongHo
J
Moon
Masashi
M
Inoue
Toshimitsu
T
Irei
Shin
S
Nakahira
Nobutaka
N
Hatanaka
D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000077544:Panitumumab; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery
D000911:Antibodies, Monoclonal; D009944:Organoplatinum Compounds; D000077544:Panitumumab; D002955:Leucovorin; D005472:Fluorouracil