Next Generation of Pancreatic Enzyme Replacement Therapy: Recombinant Microbial Enzymes and Finding the Perfect Lipase.
Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania. Electronic address: loweme2@upmc.edu.
Mark E
ME
Lowe
Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh/UPMC, Pittsburgh, Pennsylvania.
David C
DC
Whitcomb
D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000494:pharmacology*; D056947:Enzyme Replacement Therapy; D010188:Exocrine Pancreatic Insufficiency / Q000188:drug therapy*; D005656:Fungal Proteins / Q000494:pharmacology*; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects*; D008049:Lipase / Q000494:pharmacology*; D008066:Lipolysis / Q000187:drug effects*; D014280:Triglycerides / Q000378:metabolism*; D025062:Yarrowia / Q000201:enzymology*
D005656:Fungal Proteins; D014280:Triglycerides; D002265:Carboxylic Ester Hydrolases; D008049:Lipase