Surgical complications due to postnatal cytomegalovirus infection in a preterm infant with malrotation.
We report a case of an extremely preterm infant with intestinal malrotation who contracted postnatal systemic cytomegalovirus (CMV) infection with a complicated intestinal evolution requiring repeated surgical interventions and antiviral treatment. This report is to emphasize that prolonged gastrointestinal symptoms in extremely preterm infants fed with non-pasteurized breast milk should lead to suspicion of CMV infection. The importance of preventive measures when feeding very preterm infants with breast milk needs to be considered. Furthermore, the indications for antiviral treatment, in particular in preterm infants, need to be clarified.
Clinics of Neonatology, University Hospital and University of Lausanne, Switzerland.
Anaïs
A
Torregrossa
Pediatric Surgery, University Hospital and University of Lausanne, Switzerland.
Olivier
O
Reinberg
Department of Medical Radiology, Institutes of Pathology, Switzerland.
Leonor
L
Alamo
Institutes of Pathology, University Hospital and University of Lausanne, Switzerland.
Rosella
R
Sarro
Microbiology, University Hospital and University of Lausanne, Switzerland.
Pascal
P
Meylan
Clinics of Neonatology, University Hospital and University of Lausanne, Switzerland.
Matthias
M
Roth-Kleiner
D001942:Breast Feeding / Q000009:adverse effects*; D003587:Cytomegalovirus / Q000235:genetics; D003586:Cytomegalovirus Infections / Q000209:etiology* / Q000821:virology; D004279:DNA, Viral / Q000032:analysis; D004065:Digestive System Abnormalities / Q000601:surgery*; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D018445:Infectious Disease Transmission, Vertical; D045822:Intestinal Volvulus / Q000601:surgery*; D008297:Male; D008895:Milk, Human / Q000821:virology*; D013530:Surgical Wound Infection / Q000209:etiology* / Q000821:virology
D004279:DNA, Viral
cytomegalovirus; ganciclovir; intestinal malformation; postnatal CMV infection; prematurity