A ratiometric two-photon fluorescent probe for hydrazine and its applications.
A ratiometric two-photon fluorescent probeTNQwas developed based on quinoline platform to detect hydrazine (N2H4) with high selectivity.TNQexhibited large two-photon absorption cross sections at 710 nm (250 GM) and excellent ratiometric two-photon fluorescent detection signal for hydrazine.TNQwas also successfully applied to selectively detect hydrazine vapor even at a concentration down to 0.05%. Cell cytotoxicity and bio-imaging studies revealed that probeTNQwas cell-permeable and could be used to detect hydrazine in living cells with low cytotoxicity under two-photon excitation.
Department of Chemistry, Anhui University, Hefei, 230601, China. ; Center for Atomic Engineering of Advanced Material, Anhui University, Hefei, 230601, China.
Shenglong
S
Yu
Department of Chemistry, Anhui University, Hefei, 230601, China. ; Center for Atomic Engineering of Advanced Material, Anhui University, Hefei, 230601, China.
Shuxin
S
Wang
Department of Chemistry, Anhui University, Hefei, 230601, China. ; Center for Atomic Engineering of Advanced Material, Anhui University, Hefei, 230601, China.
Haizhu
H
Yu
Department of Chemistry, Anhui University, Hefei, 230601, China. ; Center for Atomic Engineering of Advanced Material, Anhui University, Hefei, 230601, China.
Yan
Y
Feng
Department of Chemistry and Biochemistry, BioFrontiers Institute, University of Colorado at Boulder, Boulder, CO 80309, USA.
Shuting
S
Zhang
Department of Chemistry, Anhui University, Hefei, 230601, China. ; Center for Atomic Engineering of Advanced Material, Anhui University, Hefei, 230601, China.
Manzhou
M
Zhu
Department of Chemistry and Biochemistry, BioFrontiers Institute, University of Colorado at Boulder, Boulder, CO 80309, USA.
Hang
H
Yin
Department of Chemistry, Anhui University, Hefei, 230601, China. ; Center for Atomic Engineering of Advanced Material, Anhui University, Hefei, 230601, China.
Xiangming
X
Meng
Fluorescent probe; Hydrazine; Hydrazine vapor detection; Ratiometric; Two-photon