Peptide Microarrays for Medical Applications in Autoimmunity, Infection, and Cancer.
The diversity of the antigen-specific humoral immune response reflects the interaction of the immune system with pathogens and autoantigens. Peptide microarray analysis opens up new perspectives for the use of antibodies as diagnostic biomarkers and provides unique access to a more differentiated serological diagnosis. This review focusses on latest applications of peptide microarrays for the serologic medical diagnosis of autoimmunity, infectious diseases, and cancer.
Department of Gastroenterology and Molecular Cancer Research Center (MKFZ), Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany. carsten.groetzinger@charite.de.
Carsten
C
Grötzinger
D000818:Animals; D001323:Autoantibodies / Q000276:immunology; D015551:Autoimmunity; D001424:Bacterial Infections / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D009369:Neoplasms / Q000276:immunology*; D040081:Protein Array Analysis / Q000379:methods*; D014777:Virus Diseases / Q000175:diagnosis / Q000276:immunology
D001323:Autoantibodies
Autoantibody; Cancer; Infection; Peptide microarray; Serodiagnostics