Visible light-initiated interfacial thiol-norbornene photopolymerization for forming islet surface conformal coating.
A cytocompatible visible light-mediated interfacial thiol-norbornene photopolymerization scheme was developed for creating hydrogel conformal coating on pancreatic islets. The step-growth thiol-norbornene reaction affords high consistency and tunability in gel coating thickness. Furthermore, isolated islets coated with thiol-norbornene gel maintained their viability and functionin vitro.
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Han
H
Shih
Departments of Pediatrics, Medicine, Cellular and Integrative Physiology, and Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
Raghavendra G
RG
Mirmira
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA. ; Department of Biomedical Engineering, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Chien-Chi
CC
Lin