Reusable acoustic tweezers for disposable devices.
We demonstrate acoustic tweezers used for disposable devices. Rather than forming an acoustic resonance, we locally transmitted standing surface acoustic waves into a removable, independent polydimethylsiloxane (PDMS)-glass hybridized microfluidic superstrate device for micromanipulation. By configuring and regulating the displacement nodes on a piezoelectric substrate, cells and particles were effectively patterned and transported into said superstrate, accordingly. With the label-free and contactless nature of acoustic waves, the presented technology could offer a simple, accurate, low-cost, biocompatible, and disposable method for applications in the fields of point-of-care diagnostics and fundamental biomedical studies.
Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA. junhuang@psu.edu.
Feng
F
Guo
Yuliang
Y
Xie
Sixing
S
Li
James
J
Lata
Liqiang
L
Ren
Zhangming
Z
Mao
Baiyang
B
Ren
Mengxi
M
Wu
Adem
A
Ozcelik
Tony Jun
TJ
Huang
D000162:Acoustics / Q000295:instrumentation*; D004129:Dimethylpolysiloxanes / Q000737:chemistry*; D004867:Equipment Design; D005898:Glass / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D056656:Lab-On-A-Chip Devices / Q000191:economics; D008846:Micromanipulation / Q000191:economics / Q000295:instrumentation*; D019095:Point-of-Care Systems / Q000191:economics; D013016:Sound
D004129:Dimethylpolysiloxanes; C013830:baysilon