Resolution of Hepatic Artery Thrombosis in 2 Pediatric Liver Transplant Patients.
Hepatic artery thrombosis (HAT) is a serious complication after liver transplantation. This is the first report of spontaneous resolution of HAT in pediatric liver transplant patients on low molecular weight heparin therapy. A total of 2 patients, a 26-month-old boy who presented with acute liver failure and required emergent liver transplantation and a 15-year-old boy with ulcerative colitis and autoimmune hepatitis-primary sclerosing cholangitis overlap underwent liver transplantation for progressive cirrhosis; both developed HAT during the postoperative period. They were both treated with low molecular weight heparin. Follow-up imaging for both patients showed resolution of HAT without evidence of collateral flow.
*Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania †Division of Gastroenterology, Hepatology and Nutrition ‡Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA.
Anna M
AM
Banc-Husu
Sudha A
SA
Anupindi
Henry C
HC
Lin
D000293:Adolescent; D000925:Anticoagulants / Q000627:therapeutic use; D002675:Child, Preschool; D000072226:Computed Tomography Angiography; D042241:Early Diagnosis; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006499:Hepatic Artery / Q000000981:diagnostic imaging / Q000187:drug effects / Q000503:physiopathology* / Q000637:transplantation; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery; D017114:Liver Failure, Acute / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000517:prevention & control; D012075:Remission, Spontaneous; D055502:Secondary Prevention; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control; D018615:Ultrasonography, Doppler, Color
D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight