SnapShot: antiviral restriction factors.
Restriction factors are cellular proteins that inhibit viruses at different steps of their replication cycle and represent an important first line of defense against viral pathogens. This SnapShot provides an overview of cell-intrinsic antiviral factors, describes their properties, and illustrates the striking variety of antiviral mechanisms as well the sophisticated viral countermeasures. To view this SnapShot, open or download the PDF.
Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
Silvia F
SF
Kluge
Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
Daniel
D
Sauter
Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.
Frank
F
Kirchhoff
D000818:Animals; D002477:Cells / Q000821:virology*; D054884:Host-Pathogen Interactions; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism; D014777:Virus Diseases / Q000276:immunology / Q000378:metabolism*; D014780:Viruses / Q000378:metabolism
D047908:Intracellular Signaling Peptides and Proteins