Coincidence of obesity associated with cardio-renal abnormalities in Thais obese population.
OBJECTIVE
To investigate the patterns and relationship among the metabolic syndrome (MS), coronary heart disease (CHD) and kidney function.


METHODS
A cross-sectional secondary data set of 9359 individuals, age 30-74 years, receiving annual health check-up in 2012 were used in this studied. Identification of MS and CHD development was determined by International Diabetes Federation criteria and Framingham risk score, respectively, while kidney function was assessed by using the estimate glomerulus filtration rate (eGFR) and chronic kidney disease epidemiology (CKD-EPI) formula.


RESULTS
The prevalence of MS was 16.1%. The majority pattern of MS in male displayed abnormalities of body mass index (BMI) plus triglyceride and blood pressure (BP). Most of them had high risk of CHD, and kidney function in stage 1 and 2. Furthermore, abnormalities of BMI plus BP and blood glucose were the main components related to high risk of CHD, and stage 1 of kidney function in female.


CONCLUSIONS
This finding showed the cleared pattern of the sequential abnormality factors which potentially use for setting the activity and empowerment team to prevention, promotion, and treatment strategy in MS patients. Particularly, BMI is the first assessment and then follow by blood pressure and blood sugar which could be used as the guideline for reducing MS associated with CHD and kidney disorder in Thai population.
Department of Clinical Chemistry, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand. Electronic address: prabhop.dan@mahidol.ac.th.
Prabhop
P
Dansethakul
Center of Medical Laboratory Services, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand.
Arunsri
A
Chuedoung
Center of Data Mining and Biomedical Informatics, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand.
Apilak
A
Worachartcheewan
Center of Medical Laboratory Services, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand.
Pradit
P
Panichanapan
Department of Clinical Chemistry, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand.
Phannee
P
Pidetcha
D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000150:complications / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D015994:Incidence; D007674:Kidney Diseases / Q000150:complications / Q000453:epidemiology*; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000453:epidemiology*; D015995:Prevalence; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology; D013785:Thailand / Q000453:epidemiology
Chronic kidney disease; Coronary heart disease; Metabolic syndrome; Obesity; eGFR