Draft genome sequences of three chemically rich actinomycetes isolated from Mediterranean sponges.
Metabolomic analysis has shown the chemical richness of the sponge-associated actinomycetes Streptomyces sp. SBT349, Nonomureae sp. SBT364, and Nocardiopsis sp. SBT366. The genomes of these actinomycetes were sequenced and the genomic potential for secondary metabolism was evaluated. Their draft genomes have sizes of 8.0, 10, and 5.8 Mb having 687, 367, and 179 contigs with a GC content of 71.6, 70.7, and 72.7%, respectively. Moreover, antiSMASH 3.0 predicted 108, 149, and 75 secondary metabolite gene clusters, respectively which highlight the metabolic capacity of the three actinomycete species to produce diverse classes of natural products.
Department of Marine Microbiology, GEOMAR Helmholtz Centre for Ocean Research, Kiel, Germany.
Hannes
H
Horn
Department of Marine Microbiology, GEOMAR Helmholtz Centre for Ocean Research, Kiel, Germany.
Cheng
C
Cheng
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, The John Arbuthnott Building, Glasgow, UK.
RuAngelie
R
Edrada-Ebel
Department of Marine Microbiology, GEOMAR Helmholtz Centre for Ocean Research, Kiel, Germany.
Ute
U
Hentschel
Department of Marine Microbiology, GEOMAR Helmholtz Centre for Ocean Research, Kiel, Germany. Electronic address: usama.ramadan@uni-wuerzburg.de.
Usama Ramadan
UR
Abdelmohsen
D039903:Actinobacteria / Q000235:genetics* / Q000302:isolation & purification* / Q000378:metabolism; D000818:Animals; D004269:DNA, Bacterial / Q000235:genetics; D015964:Gene Expression Regulation, Bacterial; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D011161:Porifera / Q000382:microbiology*; D012329:RNA, Bacterial / Q000235:genetics; D013302:Streptomyces / Q000235:genetics* / Q000302:isolation & purification* / Q000378:metabolism
D004269:DNA, Bacterial; D012329:RNA, Bacterial