A Strategy to Develop Bioactive Nanoarchitecture Cellulose: Sustained Release and Multifarious Applications.
Cellulose membranes were engineered to produce hydrophobic surfaces via a simple and soft chemical process to introduce multifunctional properties of an otherwise hydrophilic cellulose surface with polymer-grafted nanosilver to form a core-shell nanostructure. A superhydrophobic domain of the polymer on cellulose was created through the amide bond formation between the anhydride units of the polymer and the aminosiloxane-functionalized cellulose through layer-over-layer formulation. This formulation was confirmed through XPS, XRD, 29Si-NMR, and FTIR studies. Further, SEM and TEM analysis revealed that short linear silver nanowires were uniformly obtained with an average diameter of 60 nm and length of 288 nm, using a mild reducing agent at 60 degrees C, which resulted in a hierarchical cellulose surface. The nanosilver colloids released from the hierarchical cellulose surface were stabilized by the polymer matrix in solution, which led to a decrease in the rate of formation of Ag+ enhancing the material's killing efficacy against microbes. This biodegradable nanocomposite-based cellulose hierarchical surface development has potential for application as superhydrophobic membranes for oil-water separation, antimicrobial activity, and pH-triggered sustained release of colloidal silver for wound healing, which could possibly be applied for use as smart bandages.
Sembanadar
S
Karuppusamy
Annamalai
A
Pratheepkumar
Perumal
P
Dhandapani
Sundaram
S
Maruthamuthu
Manickam Anbu
MA
Kulandainathan
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000138:chemical synthesis; D018407:Bacterial Physiological Phenomena / Q000187:drug effects*; D002470:Cell Survival / Q000187:drug effects; D002482:Cellulose / Q000138:chemical synthesis*; D003460:Crystallization / Q000379:methods; D003692:Delayed-Action Preparations / Q000008:administration & dosage / Q000138:chemical synthesis*; D004058:Diffusion; D015195:Drug Design; D057927:Hydrophobic and Hydrophilic Interactions; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry* / Q000648:ultrastructure; D053769:Nanocapsules / Q000008:administration & dosage / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D012834:Silver / Q000008:administration & dosage / Q000737:chemistry; D013499:Surface Properties
D000900:Anti-Bacterial Agents; D003692:Delayed-Action Preparations; D053769:Nanocapsules; D012834:Silver; D002482:Cellulose