Transcriptome analysis of bladder biopsy from interstitial cystitis/bladder pain syndrome patients.
Interstitial cystitis and bladder pain syndrome (IC/BPS) are terms used to describe a heterogeneous chronic pelvic and bladder pain disorder. Despite its significant prevalence, the disease etiology is not well understood and providing diagnosis and treatment can be challenging. In our study, published recently in the Journal of Urology (Colaco et al., 2014), we describe the use of microarrays as a tool to characterize IC/BPS and to determine if there are clinical factors that correlate with gene expression. This data-in-brief article describes the methodology for that study, including data analysis, in further detail. Deposited data can be found in the Gene Expression Omnibus (GEO) database: GSE57560.
Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; Department of Urology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Stephen J
SJ
Walker
Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; Department of Urology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Marc
M
Colaco
Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; Department of Urology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
David S
DS
Koslov
Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA ; Department of Urology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Tristan
T
Keys
Department of Urology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Robert J
RJ
Evans
Department of Urology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Gopal H
GH
Badlani
Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Karl-Erik
KE
Andersson
Biomarker profiling; Gene expression; Interstitial cystitis