Endometriosis in a kidney with focal xanthogranulomatous pyelonephritis and a perinephric abscess.
BACKGROUND
The presence of endometriosis in the kidney is extremely rare. We report a case of endometriosis in renal parenchyma incidentally found in a malfunctioning kidney removed because of xanthogranulomatous pyelonephritis.


METHODS
A 53-year-old Chinese premenopausal woman presented with intermittent right flank pain for many years. Imaging studies revealed a contracted non-functioning right kidney and a perinephric abscess. The contracted kidney was considered to have resulted from chronic pyelonephritis. The abscess was drained. The patient subsequently underwent a right nephrectomy. Histology revealed endometriosis of renal parenchyma in addition to xanthogranulomatous pyelonephritis and a perinephric abscess. No evidence of endometriosis was identified at the pelvic site. The patient was symptom-free after operation.


CONCLUSIONS
Endometriosis is a common benign condition in women of reproductive age that is characterized by the presence of endometrial glands and stroma outside the uterine cavity, which affects either genital or extragenital sites. Involvement of the urinary tract is rare. Among the urinary tract endometriosis, only a few cases involve the kidney. Renal endometriosis is difficult to diagnose; a final diagnosis relies on the pathohistologic findings. Treatment involves hormonal manipulation or a hysterectomy with bilateral salpingo-oophorectomy. Whether a nephrectomy required depends on the level of renal function. Although extremely rare, renal endometriosis should be part of the differential diagnostic spectrum when a contracted, non-functioning kidney is present. Early diagnosis might have prevented an unnecessary nephrectomy in cases of uncomplicated renal endometriosis.
Department of Pathology, Buddhist Tzu Chi General Hospital, 707 Chung Yang Road, Section 3, Hualien, Taiwan. chiuhsuan.cheng@gmail.com.
Chiu-Hsuan
CH
Cheng
Department of Urology, Buddhist Tzu Chi General Hospital, 707 Chung Yang Road, Section 3, Hualien, Taiwan. hck@tzuchi.com.tw.
Hann-Chorng
HC
Kuo
Department of Pathology, Buddhist Tzu Chi General Hospital, 707 Chung Yang Road, Section 3, Hualien, Taiwan. pathology@email.com.|School of Medicine, Tzu Chi University, Hualien, Taiwan. pathology@email.com.
Borcherng
B
Su
D000038:Abscess / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D004715:Endometriosis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D033162:Incidental Findings; D007668:Kidney / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009392:Nephrectomy; D017697:Premenopause; D011705:Pyelonephritis, Xanthogranulomatous / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery