Periarrest intestinal bacterial translocation and resuscitation outcome.
During the periarrest period, intestinal ischemia may result in barrier dysfunction and bacterial translocation, which has clear mechanistic links to inflammation and cascade stimulation, especially in patients who are treated with therapeutic hypothermia. Despite optimal management, periarrest bacterial translocation may worsen the outcome of cardiac arrest victims.
National and Kapodistrian University of Athens, Medical School, MSc "Cardiopulmonary Resuscitation", Athens, Greece; Hellenic Society of Cardiopulmonary Resuscitation, Athens, Greece. Electronic address: thanoschalkias@yahoo.gr.
Athanasios
A
Chalkias
Department of Pharmacy Practice, Midwestern University, Chicago College of Pharmacy, Downers Grove, IL, USA.
Marc H
MH
Scheetz
Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, USA.
Anil
A
Gulati
National and Kapodistrian University of Athens, Medical School, MSc "Cardiopulmonary Resuscitation", Athens, Greece; Hellenic Society of Cardiopulmonary Resuscitation, Athens, Greece; Department of Pharmaceutical Sciences, Midwestern University, Chicago, IL, USA.
Theodoros
T
Xanthos
D016470:Bacteremia / Q000276:immunology*; D018988:Bacterial Translocation; D016887:Cardiopulmonary Resuscitation; D006323:Heart Arrest / Q000378:metabolism / Q000628:therapy*; D006801:Humans; D007036:Hypothermia, Induced; D007249:Inflammation; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000098:blood supply; D065666:Mesenteric Ischemia / Q000378:metabolism*; D018384:Oxidative Stress
Bacterial translocation; Cardiac arrest; Cardiopulmonary resuscitation; Intestine; Ischemia