Successful treatment of fetal hemolytic disease due to glucose phosphate isomerase deficiency (GPI) using repeated intrauterine transfusions: a case report.
Hemolytic anemia due to GPI deficiency can be severe and life threatening during fetal life. When parents decline invasive testing, ultrasound monitoring of fetuses at risk is feasible. Intrauterine transfusion can be effective for the treatment of severe fetal anemia due to GPI deficiency.
Department of Prenatal Diagnosis and Therapy, Leiden University Medical Center Leiden, the Netherlands.
Phebe N
PN
Adama van Scheltema
Department of Prenatal Diagnosis and Therapy, Leiden University Medical Center Leiden, the Netherlands.
Ai
A
Zhang
Department of Pediatric Hematology, Leiden University Medical Center Leiden, the Netherlands.
Lynne M
LM
Ball
Department of Neonatology, Leiden University Medical Center Leiden, the Netherlands.
Sylke J
SJ
Steggerda
Department of Clinical Chemistry and Hematology, University Medical Center Utrecht Utrecht, the Netherlands.
Richard
R
van Wijk
Department of Clinical Genetics, Leiden University Medical Center Utrecht, the Netherlands.
Dietje E
DE
Fransen van de Putte
Department of Prenatal Diagnosis and Therapy, Leiden University Medical Center Leiden, the Netherlands.
Inge L
IL
van Kamp
Fetal anemia; GPI deficiency; intrauterine transfusion