BGT: efficient and flexible genotype query across many samples.
BGT is a compact format, a fast command line tool and a simple web application for efficient and convenient query of whole-genome genotypes and frequencies across tens to hundreds of thousands of samples. On real data, it encodes the haplotypes of 32 488 samples across 39.2 million SNPs into a 7.4 GB database and decodes up to 420 million genotypes per CPU second. The high performance enables real-time responses to complex queries.


METHODS
https://github.com/lh3/bgt.
Medical Population Genetics Program, Broad Institute, Cambridge, MA 02142, USA.
Heng
H
Li
D000465:Algorithms; D016208:Databases, Factual; D066264:Datasets as Topic; D014644:Genetic Variation / Q000235:genetics*; D015894:Genome, Human; D005838:Genotype; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D012984:Software