Ethanol Lock Therapy for the Treatment of Intravenous Catheter Infections That Have Failed Standard Treatment.
This study used ethanol lock therapy (ELT) to treat intravenous catheter infections that had failed standard intravenous antimicrobial treatment. Of 15 patients enrolled, 13 were successfully treated with ELT. Twenty-one organisms were identified: 12 bacteria, 9 fungi. Eight of the 9 fungi were eradicated, and no patient became hemodynamically unstable on treatment.
University of Michigan, Ann Arbor, Michigan.
Roland Alexander
RA
Blackwood
University of Michigan, Ann Arbor, Michigan.
Mohamad
M
Issa
University of Michigan, Ann Arbor, Michigan.
Kristin
K
Klein
University of Michigan, Ann Arbor, Michigan.
Rajen
R
Mody
University of Michigan, Ann Arbor, Michigan.
Michelle
M
Willers
University of Michigan, Ann Arbor, Michigan.
Daniel
D
Teitelbaum
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy*; D055499:Catheter-Related Infections / Q000188:drug therapy*; D062905:Central Venous Catheters / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D004203:Disinfection; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male
D000900:Anti-Bacterial Agents; D000431:Ethanol
catheter infections; ethanol locks; fungal infections