Toxoplasma gondii seroprevalence: 30-year trend in an HIV-infected US military cohort.
To determine if Toxoplasma gondii IgG antibody prevalence is declining in HIV-infected persons, we analyzed data (1984-2013) from the US Military HIV Natural History Study. We found that T. gondii seroprevalence at enrollment was associated with age and decreased significantly after 1995 (P=0.004), similar to the general US population.
Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, TX, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. Electronic address: thomas.a.obryan2.ctr@mail.mil.
Thomas A
TA
O'Bryan
Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, TX, USA.
Jason F
JF
Okulicz
Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, TX, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
William P
WP
Bradley
Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; Walter Reed National Military Medical Center, Bethesda, MD, USA.
Anuradha
A
Ganesan
Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, TX, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Scott E
SE
Merritt
Infectious Disease Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Brian K
BK
Agan
D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008889:Military Personnel; D016036:Seroepidemiologic Studies; D014123:Toxoplasmosis / Q000453:epidemiology*; D014481:United States / Q000453:epidemiology
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G
Antibody; Human immunodeficiency virus; Prevalence; Toxoplasma gondii; Trend