Corticosteroids and Spontaneous Coronary Artery Dissection: A New Predisposing Factor?
We describe the case of a 39-year-old woman with spontaneous coronary artery dissection (SCAD) of the left circumflex artery. We postulate that her SCAD was precipitated by high-dose corticosteroid use for the treatment of optic neuritis. The epidemiology and known risk factors of SCAD are reviewed with an additional focus on the effect of corticosteroids on the cardiovascular system.
University of Toronto Adult Congenital Heart Disease Program, Toronto, Ontario, Canada.
Michelle L
ML
Keir
Prairie Vascular Research Network, University of Saskatchewan, Regina, Saskatchewan, Canada. Electronic address: payamde@gmail.com.
Payam
P
Dehghani
D000328:Adult; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D003330:Coronary Vessel Anomalies / Q000139:chemically induced* / Q000175:diagnosis; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage / Q000009:adverse effects*; D007275:Injections, Intravenous; D009902:Optic Neuritis / Q000188:drug therapy*; D012307:Risk Factors; D014652:Vascular Diseases / Q000139:chemically induced / Q000151:congenital* / Q000175:diagnosis
D005938:Glucocorticoids; D006854:Hydrocortisone