Antipsychotic Use in a Diverse Population With Dementia: A Retrospective Review of the National Alzheimer's Coordinating Center Database.
A cross-sectional analysis examined medication records in the National Alzheimer's Coordinating Center Database for community-dwelling patients with dementia who visited an Alzheimer's Disease Center between 2008 and 2014. Hispanic participants had a 1.62-fold greater use of antipsychotic medications, which was largely accounted for by a higher prevalence of neuropsychiatric symptoms and more severe dementia compared with non-Hispanic whites. These results are consistent with reports of later transition to nursing home care among Hispanic participants. Further studies are needed to clarify ethnic differences in how families and physicians address dementia progression and neuropsychiatric symptoms in community-dwelling patients with dementia.
From the Dept. of Psychiatry and Behavioral Sciences (GLX, LH) and the Division of Biostatistics, Dept. of Public Health Sciences (TF, LAB), Alzheimer's Disease Center, and the Latino Aging Resource Center (LH), University of California, Davis.
Glen L
GL
Xiong
From the Dept. of Psychiatry and Behavioral Sciences (GLX, LH) and the Division of Biostatistics, Dept. of Public Health Sciences (TF, LAB), Alzheimer's Disease Center, and the Latino Aging Resource Center (LH), University of California, Davis.
Teresa
T
Filshtein
From the Dept. of Psychiatry and Behavioral Sciences (GLX, LH) and the Division of Biostatistics, Dept. of Public Health Sciences (TF, LAB), Alzheimer's Disease Center, and the Latino Aging Resource Center (LH), University of California, Davis.
Laurel A
LA
Beckett
From the Dept. of Psychiatry and Behavioral Sciences (GLX, LH) and the Division of Biostatistics, Dept. of Public Health Sciences (TF, LAB), Alzheimer's Disease Center, and the Latino Aging Resource Center (LH), University of California, Davis.
Ladson
L
Hinton
D001741:Black or African American; D000368:Aged; D000369:Aged, 80 and over; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D016208:Databases, Factual; D003704:Dementia / Q000175:diagnosis* / Q000188:drug therapy*; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome; D044465:White People
D014150:Antipsychotic Agents