[Low grade parosteal osteosarcoma. Clinical and oncological outcomes].
The objective of the study was to analyze a group of patients with low grade parosteal osteosarcoma treated with limb salvage surgery and reconstructed with bone allograft. A retrospective review from our oncologic data base between 1980 and 2010 was done and all patients with diagnosis of low grade parosteal osteosarcoma, treated with limb salvage surgery and reconstructed with allograft were included. Twenty-two patients were included for the analysis. The mean age was 32±11 years (10-59) y the mean follow-up 93±69 months (8-237). Ten year overall survival of the series was 91% (95% CI: 79-100). Four patients developed local recurrence, 2 of them histological classified after the resection dedifferentiated parosteal osteosarcoma. Two patients developed distant recurrence, being the lung the only site of metastasis. Ten year limb salvage reconstruction survival was 65% (95% CI: 44-86). Long term survival rate in low grade parosteal osteosarcoma is over 90%. Surgical resection wide margin should be the elective treatment and biological limb salvage reconstruction is a good alternative.
Servicio de Ortopedia y Traumatología, Hospital Italiano de Buenos Aires, Argentina. E-mail: nachoalbergo@hotmail.com.
José I
JI
Albergo
Germán L
GL
Farfalli
Miguel A
MA
Ayerza
Domingo L
DL
Muscolo
Luis A
LA
Aponte-Tinao
D000293:Adolescent; D000328:Adult; D016025:Bone Transplantation / Q000401:mortality*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D023821:Limb Salvage / Q000379:methods*; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D012516:Osteosarcoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D035583:Rare Diseases / Q000401:mortality / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D017741:Survivors; D016896:Treatment Outcome; D055815:Young Adult
allograft reconstruction; local recurrence; overall survival; parosteal osteosarcoma