Frozen Autograft-Prosthesis Composite Reconstruction in Malignant Bone Tumors.
Several methods are available using an endoprosthesis or biological reconstruction for malignant bone tumors. Methods that use allograft-prosthesis composites have shown promising results. In 1999, the authors developed a method of reconstruction that uses a tumor-bearing autograft treated with liquid nitrogen. This technique was modified to produce a pedicle frozen autograft to maintain anatomical continuity on one side. In this study, the results of bone reconstructions using frozen autograft-prosthesis composites were retrospectively evaluated. The demographic data, histological records, surgical procedures, functional scores, and complications of 22 patients who had bone sarcoma or metastasis and at least 2 years of follow-up were reviewed. There were 19 patients with primary bone sarcoma and 3 with bone metastasis. Average age was 36 years (range, 9-73 years), and mean follow-up was 63 months (range, 24-176 months). Reconstructions were performed on 10 proximal femurs, 5 distal femurs, 4 proximal tibias, 1 proximal humerus, 1 proximal radius, and 1 hemipelvis. There were 12 pedicle-freezing and 10 free-freezing procedures. Union rate was 90% (9/10), and average union time was 9.5 months. Average Musculoskeletal Tumor Society score was 89.3%. Complications included 1 fracture, 2 infections, 3 soft tissue recurrences, and 1 posterior interosseous nerve palsy. The authors concluded that the frozen autograft-prosthesis composite demonstrated excellent Musculoskeletal Tumor Society scores, a low complication rate, and a good union rate and was superior when used with the pedicle-freezing technique.
Saran
S
Subhadrabandhu
Akihiko
A
Takeuchi
Norio
N
Yamamoto
Toshiharu
T
Shirai
Hideji
H
Nishida
Katsuhiro
K
Hayashi
Shinji
S
Miwa
Hiroyuki
H
Tsuchiya
D000293:Adolescent; D000328:Adult; D000368:Aged; D064592:Autografts; D001859:Bone Neoplasms / Q000556:secondary / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods*; D002277:Carcinoma / Q000556:secondary / Q000601:surgery; D002292:Carcinoma, Renal Cell / Q000556:secondary / Q000601:surgery; D002648:Child; D002813:Chondrosarcoma / Q000601:surgery*; D005260:Female; D005269:Femur / Q000601:surgery*; D006801:Humans; D006811:Humerus / Q000601:surgery; D007680:Kidney Neoplasms / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D012516:Osteosarcoma / Q000601:surgery*; D010384:Pelvic Bones / Q000601:surgery; D019919:Prosthesis Implantation / Q000379:methods*; D011884:Radius / Q000601:surgery; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D012782:Shoulder / Q000601:surgery; D013977:Tibia / Q000601:surgery*; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D055815:Young Adult