Selective effects of acute alcohol intake on the prospective and retrospective components of a prospective-memory task with emotional targets.
BACKGROUND
Prospective memory involves remembering to do something in the future and has a prospective component (remembering that something must be done) and a retrospective component (remembering what must be done and when it must be done). Initial studies reported an impairment in prospective-memory performance due to acute alcohol consumption. Retrospective-memory studies demonstrated that alcohol effects vary depending on the emotionality of the information that needs to be learned.


OBJECTIVE
The aim of the present study was to investigate possible differential effects of a mild acute alcohol dose (0.4 g/kg) on the prospective and retrospective components of prospective memory depending on cue valence.


METHODS
Seventy-five participants were allocated to an alcohol or placebo group and performed a prospective-memory task in which prospective-memory cue valence was manipulated (negative, neutral, positive). The multinomial model of event-based prospective memory (Smith and Bayen 2004) was used to measure alcohol and valence effects on the two prospective-memory components separately.


RESULTS
Overall, no main effect of alcohol or valence on prospective-memory performance occurred. However, model-based analyses demonstrated a significantly higher retrospective component for positive compared with negative cues in the placebo group. In the alcohol group, the prospective component was weaker for negative than for neutral cues and the retrospective component was stronger for positive than for neutral cues. Group comparisons showed that the alcohol group had a significantly lower prospective component for negative cues and a lower retrospective component for neutral cues.


CONCLUSIONS
This is the first study to demonstrate selective alcohol effects on prospective-memory components depending on prospective-memory cue valence.
Nora T
NT
Walter
Ute J
UJ
Bayen
D000293:Adolescent; D000328:Adult; D000339:Affect / Q000187:drug effects; D000428:Alcohol Drinking / Q000523:psychology*; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D003118:Color Perception / Q000187:drug effects; D003463:Cues; D004311:Double-Blind Method; D004644:Emotions / Q000187:drug effects*; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D061212:Memory, Episodic; D011597:Psychomotor Performance / Q000187:drug effects; D021641:Recognition, Psychology / Q000187:drug effects; D055815:Young Adult
D002492:Central Nervous System Depressants; D000431:Ethanol