A Direct Path to Action Initiation.
In this issue of Neuron, Sippy et al. (2015) provide the clearest evidence to date that information is differentially encoded in the direct and indirect pathways of the striatum. The results support the classical notion that the direct pathway plays a critical role in initiating actions.
The Gladstone Institutes, San Francisco, CA, 94158, USA.
Christopher H
CH
Donahue
The Gladstone Institutes, San Francisco, CA, 94158, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: akreitzer@gladstone.ucsf.edu.
Anatol C
AC
Kreitzer
D000818:Animals; D003342:Corpus Striatum / Q000166:cytology* / Q000502:physiology*; D006040:Goals; D009474:Neurons / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D012201:Reward
action; basal ganglia; direct pathway; indirect pathway