The PHD2 oxygen sensor paves the way to metastasis.
Laboratory of Angiogenesis and Neurovascular Link, Department of Oncology, KU Leuven, Leuven, Belgium.|Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, VIB, Leuven, Belgium.
Anna
A
Kuchnio
Laboratory of Angiogenesis and Neurovascular Link, Department of Oncology, KU Leuven, Leuven, Belgium.|Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, VIB, Leuven, Belgium.
Mieke
M
Dewerchin
Laboratory of Angiogenesis and Neurovascular Link, Department of Oncology, KU Leuven, Leuven, Belgium.|Laboratory of Angiogenesis and Neurovascular Link, Vesalius Research Center, VIB, Leuven, Belgium.
Peter
P
Carmeliet
D000818:Animals; D001943:Breast Neoplasms / Q000201:enzymology* / Q000473:pathology*; D015687:Cell Hypoxia / Q000502:physiology; D005260:Female; D006801:Humans; D064799:Hypoxia-Inducible Factor-Proline Dioxygenases / Q000378:metabolism*; D051379:Mice; D009362:Neoplasm Metastasis; D010100:Oxygen / Q000378:metabolism
C490190:EGLN1 protein, human; D064799:Hypoxia-Inducible Factor-Proline Dioxygenases; D010100:Oxygen
breast cancer; cancer associated fibroblast; metastasis; vessel normalization