Rapid retraction of microvolume aqueous plugs traveling in a wettable capillary.
We report a transport behavior-specifically, rapid retraction movement-of small (∼μL) deionized water plugs traveling in series within a small wettable tubular geometry. In this study, two water plugs separated by a certain distance in a dry cylindrical glass capillary were moved by positive pressure airflow applied at the tube inlet. As the plugs travel, a thin aqueous film is generated between the plugs as a result of the leading plug's aqueous deposition onto the inner surface of the tube. The leading plug continuously loses volume by film deposition onto the surface and eventually ruptures. Then, the lagging plug quickly travels the distance initially separating the two plugs (plug retraction). Our studies show that the rapid retraction of the lagging plug is caused by surface tension in addition to the positive pressure applied. Furthermore, the plug retraction speed is strongly affected by tube radius and the distance between the plugs.
Department of Biomedical Engineering, Columbia University , New York, New York 10027, USA.
Jinho
J
Kim
Department of Biomedical Engineering, Columbia University , New York, New York 10027, USA.
John D
JD
O'Neill
Gordana
G
Vunjak-Novakovic