Functionalized nanomaterials: are they effective to perform gene delivery to difficult-to-transfect cells with no cytotoxicity?
Nanodiamonds (NDs), multiwalled carbon nanotubes (MWCNTs) and gold nanorods (NRs) can be functionalized to promote gene delivery to hard-to-transfect cells with higher transfection efficiency than cationic lipids, and inducing less cell death.
Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. rrresende@hotmail.com contato@institutonanocell.org.br and Nanocell Institute, Divinópolis, Brazil.
F M P
FM
Tonelli
Cell Biology Laboratory, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
S M S N
SM
Lacerda
Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. rrresende@hotmail.com contato@institutonanocell.org.br and Nanocell Institute, Divinópolis, Brazil.
N C O
NC
Paiva
Chemistry of Nanostructures Laboratory, Nuclear Technology Development Center, Federal University of Minas Gerais, Belo Horizonte, Brazil.
F G
FG
Pacheco
Cell Electrophysiology Laboratory, Department of Physiology and Pharmacology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
S R A
SR
Scalzo Junior
Excitable Membranes Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
F H P
FH
de Macedo
Excitable Membranes Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
J S
JS
Cruz
Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. rrresende@hotmail.com contato@institutonanocell.org.br and Nanocell Institute, Divinópolis, Brazil.
M C X
MC
Pinto
Laboratory of Chemical-Biological Interactions and Animal Reproduction, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
J D
JD
Corrêa Junior
Nanomaterials Laboratory, Department of Physics, Federal University of Minas Gerais, Belo Horizonte, Brazil.
L O
LO
Ladeira
Cell Biology Laboratory, Department of Morphology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
L R
LR
França
Cell Electrophysiology Laboratory, Department of Physiology and Pharmacology, Federal University of Minas Gerais, Belo Horizonte, Brazil.
S
S
Guatimosim
Cell Signaling and Nanobiotechnology Laboratory, Department of Biochemistry and Immunology, Federal University of Minas Gerais, Belo Horizonte, Brazil. rrresende@hotmail.com contato@institutonanocell.org.br and Nanocell Institute, Divinópolis, Brazil.
R R
RR
Resende
D000818:Animals; D002460:Cell Line; D051379:Mice; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D014162:Transfection / Q000379:methods*