Schistosoma haematobium Infection That Mimics Bladder Cancer in a 66-Year-Old Ethnic Egyptian Man.
METHODS
66-year-old ethnic Egyptian man.
Hematuria.
The patient had a history of multiple episodes of gross hematuria for the past 5 years. Because the hematuria usually resolved on its own, he did not seek medical attention during that time. Bladder cancer was suspected.
The patient had a history of coronary artery disease, hypertension, nephrolithiasis, congestive heart failure, lifelong smoking, and ischemic cardiomyopathy. He has been taking the anticoagulants clopidogrel (Plavix) and warfarin (Coumadin).
The patient is originally from Egypt and has been living in the United States for the past 10 years.


RESULTS
A complete blood count showed a hemoglobin of 13.0 g per dL (reference range, 14.0 to 18.0 g per dL), hematocrit 40% (40% to 54%), red blood cell count (RBC) 4.65 × 10(9) per L (4.60 to 6.00), and platelet count 179 × 10(9) per L (150 to 450). The urinalysis results showed 3+ protein, 4+ blood, and urine RBC of greater than 100 per high power field (hpf). The urinalysis results did not indicate the presence of parasitic ova or adult parasites. Based on these results, the physician ordered cystoscopic testing, suspecting bladder cancer. Analysis of the bladder tissue showed inflammation (Image 1) and several ova that were consistent with developing Schistosoma (Image 2). Many of the ova were calcified and surrounded by severely inflamed tissue (Image 3).
Laboratory, USA Children's & Women's Hospital, Mobile, Alabama.
Celenne Morfin
CM
Zepeda
Department of Clinical Laboratory Sciences, University of West Florida, Pensacola, Florida kcoffey@uwf.edu.
Kristen H
KH
Coffey
D000368:Aged; D000818:Animals; D003937:Diagnosis, Differential; D004534:Egypt; D006801:Humans; D008297:Male; D012548:Schistosoma haematobium; D012553:Schistosomiasis haematobia / Q000175:diagnosis / Q000469:parasitology / Q000473:pathology; D001743:Urinary Bladder / Q000469:parasitology / Q000473:pathology; D001749:Urinary Bladder Neoplasms
Schistosoma haematobium; bladder cancer; clinical pathology; hematuria; infectious disease; microbiology; urinary schistosomiasis; uropathology