[Chemical Constituents of Euphorbia lunulata].
OBJECTIVE
To investigate the chemical constituents in the ethanol extract from the whole plant of Euphorbia lunulata.


METHODS
The whole plant of Euphorbia lunulata was extracted by 95% ethanol, then partitioned by system solvents with different polarity. The ethyl acetate and n-butyl alcohol extracts were separated on silica gel, Sephadex LH-20,and MCI columns. The isolated compounds were determined by detailed analysis of their spectral data.


RESULTS
Twelve compounds were isolated and identified from the ethyl acetate and n-butyl alcohol extracts of Euphorbia lunulata and the structures were identified as 7β-methoxy-stigmast-5-ene-3β-ol (1), 7β-methoxy-stigmast-5-ene-3β,22β-diol(2), asperglaucide(3), moscatin (4), p-hydroxybenzoic acid (5),3-methoxy-4-hydroxy benzoic acid(6), erigeside C(7),5,7,4'-trihydroxy flavanone(8), kaempferol(9), quercetin(10), corosolic acid(11) and acacetin (12).


CONCLUSIONS
All compounds except for 9 and 10 are reported from this plant for the first time.
Chao
C
Liu
Hui
H
Sun
Wei-ting
WT
Wang
Jin-yue
JY
Sun
Mark A
MA
Smith
D028481:Euphorbia / Q000737:chemistry*; D044949:Kaempferols; D064209:Phytochemicals / Q000737:chemistry* / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry*; D011794:Quercetin
D044949:Kaempferols; D064209:Phytochemicals; D010936:Plant Extracts; C006552:kaempferol; D011794:Quercetin