A Case Series & Review of Literature of Angiomyolipoma with Medical & Surgical Perspective.
The angiomyolipoma of renal origin is a rare benign tumour composed of fat cells, smooth muscle cells, and thick-wall blood vessels. Mostly these are sporadic origin, asymptomatic and benign in nature. Here we present two cases of Renal angiomyolipoma (AML) presenting as fever, pain, perirenal haematoma & frank haematuria. After initial stabilization, evaluated by contrast enhanced computer tomography (CECT) & diagnosed as renal angiomyolipoma because of low Hounsfield areas (10-20HU) suggestive for fat. Patient later underwent angiography with selective angioembolisation. Post intervention period was uneventful and was treated by an oral Everolimus 10 mg daily for a period of one year in first case & partial resection was done in second case. On two year follow-up both patients were doing well & had normal renal function without any recurrence. Embolisation is the emergency treatment of choice for bleeding angiomyolipoma. When preventive treatment is considered a nephron sparing approach by either transarterial embolisation or partial nephrectomy is clearly important. While angiomyolipoma in both kidneys or in solitary functioning kidneys, renal preservation is mandatory in order to avoid need for renal replacement therapy. Also, recently approved drug Everolimus may be considered for patients not suitable for surgery particularly in tumour seen with tuberous sclerosis.
Assistant Professor, Department of Urology, Postgraduate Institute of Medical Education and Research , Chandigarh, India .
Santosh
S
Kumar
Resident, Department of Urology, Postgraduate Institute of Medical Education and Research , Chandigarh, India .
Kumar
K
Jayant
Professor, Department of Urology, Postgraduate Institute of Medical Education and Research , Chandigarh, India .
Shrawan Kumar
SK
Singh
Faculty, Department of Maternal & Fetal Medicine, The University of Chicago Medicine 5841 S. Maryland Avenue, Chicago, IL 60637 .
Swati
S
Agrawal
Embolisation; Mesenchymal renal tumours; Tuberous sclerosis