[Local Microwave Hyperthermia for Advanced or Recurrent Breast Cancer].
The purpose of our study was to test the efficacy and toxicity of hyperthermia for treating breast cancer. Ten patients received treatment (AC, paclitaxel, S-1, and aromatase inhibitor) in combination with hyperthermia. The hyperthermia device was a microwave heating device with water loaded and water-cooled waveguides. The temperature was monitored subcutaneously in the skin under the aperture of the waveguide. Two patients had a partial response to treatment with only mild toxicity (grade 1 acute skin toxicity). Therefore, hyperthermia combined with chemotherapy for treating breast cancer seems to be effective and generally tolerable. A larger patient cohort is needed to confirm these results in the future.
Dept. of Internal Medicine, Seiko Hospital.
Chizuko
C
Yamamoto
Daigo
D
Yamamoto
Yu
Y
Tsubota
Noriko
N
Sueoka
Katsuhiro
K
Kawakami
Mitsuo
M
Yamamoto
D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D006979:Hyperthermia, Induced; D008872:Microwaves; D008875:Middle Aged; D009367:Neoplasm Staging; D012008:Recurrence