Direct Synthesis of Thioethers from Carboxylates and Thiols Catalyzed by FeCl3.
A new and efficient method has been developed for the synthesis of thioethers from carboxylates and thiols. The reaction proceeds via a Fe(III)-catalyzed direct displacement of carboxylates from benzylic or allylic esters by heterocyclic thiols. Short reaction times, good to excellent yields of products, and few side reactions are the significant features of the new protocol.
Natural Products Laboratory, Natural Products Division, Indian Institute of Chemical Technology , Hyderabad, India , 500007.
Kunuru
K
Venkatesham
Natural Products Laboratory, Natural Products Division, Indian Institute of Chemical Technology , Hyderabad, India , 500007.
Chitturi
C
Bhujanga Rao
Natural Products Laboratory, Natural Products Division, Indian Institute of Chemical Technology , Hyderabad, India , 500007.
Chanti Babu
CB
Dokuburra
Department of Chemistry, Oklahoma State University , 107 Physical Sciences, Stillwater, Oklahoma 74078-3071, United States.
Richard A
RA
Bunce
Natural Products Laboratory, Natural Products Division, Indian Institute of Chemical Technology , Hyderabad, India , 500007.
Yenamandra
Y
Venkateswarlu