Inflammatory Myofibroblastic Tumours of the Respiratory Tract: A Series of Three Cases with Varying Clinical Presentations and Treatment.
BACKGROUND
Inflammatory myofibroblastic tumor in the respiratory system is a rare and controversial disease. It is macroscopically well-circumscribed, non-encapsulated, firm and usually a yellowish-white mass. Histologically it is composed of the following spindled and inflammatory cells: lymphocytes, plasma cells, and histiocytes, including Touton type multinucleated giant cells.


METHODS
The series included a 49-year-old man with a tracheal inflammatory myofibroblastic tumor who complained of hoarseness; a 42-year-old man who was coughing and had a blood-stained sputum, and inflammatory myofibroblastic tumor was in the right main and intermediate bronchus; and a 32-year-old man with chest pain and inflammatory myofibroblastic tumor as a solitary peripheral nodule in the left lower lobe. In all the cases, the tumor was resected bronchoscopically and surgically.


CONCLUSIONS
Inflammatory myofibroblastic tumor of the lung and the trachea is rare. Complete resection, when possible, should be the choice of treatment. After the complete removal, prognosis is generally excellent and recurrences are rare.
Dragana
D
Tegeltija
Aleksandra
A
Lovrenski
Goran
G
Stojanović
Milorad
M
Bijelović
Ivana
I
Jeličić
Živka
Ž
Eri
D000328:Adult; D006104:Granuloma, Plasma Cell / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016896:Treatment Outcome