The effect of immunization with pneumococcal conjugated vaccines on Streptococcus pneumoniae resistance patterns in acute otitis media.
Following the introduction of 7- and 13-pneumococcal conjugate vaccines (PCVs) in Israel, we demonstrated that within Streptococcus pneumoniae (Sp) positive middle ear cultures, obtained from young children with severe acute otitis media (AOM) episodes, there were more penicillin-susceptible and less multi-drug resistant Sp isolates in PCV immunized children.
Department of Otolaryngology-Head and Neck Surgery, Edith Wolfson Medical Center, Tel Aviv University Sackler School of Medicine, Holon, Israel.
Tal
T
Marom
Faculty of Medicine, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel.
Elad
E
Avraham
Department of Otolaryngology-Head and Neck Surgery, Edith Wolfson Medical Center, Tel Aviv University Sackler School of Medicine, Holon, Israel.
Udi
U
Cinamon
Department of Otolaryngology-Head and Neck Surgery, Edith Wolfson Medical Center, Tel Aviv University Sackler School of Medicine, Holon, Israel. Electronic address: sharontamir@gmail.com.
Sharon Ovnat
SO
Tamir
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002675:Child, Preschool; D024901:Drug Resistance, Multiple, Bacterial; D004432:Ear, Middle / Q000382:microbiology; D005260:Female; D006801:Humans; D007114:Immunization; D007223:Infant; D007557:Israel; D008297:Male; D008826:Microbial Sensitivity Tests; D010033:Otitis Media / Q000382:microbiology* / Q000517:prevention & control; D011008:Pneumococcal Infections / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D022242:Pneumococcal Vaccines / Q000276:immunology / Q000494:pharmacology*; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification; D018074:Vaccines, Conjugate / Q000276:immunology / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate
Streptococcus pneumoniae; acute otitis media; antibiotic resistance; pneumococcal conjugate vaccine