Quantitative analysis of mouse corpus callosum from electron microscopy images.
This article provides morphometric analysis of 72 electron microscopy images from control (n=4) and hypomyelinated (n=2) mouse corpus callosum. Measures of axon diameter and g-ratio were tabulated across all brains from two regions of the corpus callosum and a non-linear relationship between axon diameter and g-ratio was observed. These data are related to the accompanying research article comparing multiple methods of measuring g-ratio entitled 'A revised model for estimating g-ratio from MRI' (West et al., NeuroImage, 2015).
Department of Biomedical Engineering, Vanderbilt University, United States ; Vanderbilt University Institute of Imaging Science, Vanderbilt University, United States.
Kathryn L
KL
West
Department of Biomedical Engineering, Vanderbilt University, United States ; Vanderbilt University Institute of Imaging Science, Vanderbilt University, United States.
Nathaniel D
ND
Kelm
Department of Pediatric Neurology, United States.
Robert P
RP
Carson
Department of Biomedical Engineering, Vanderbilt University, United States ; Vanderbilt University Institute of Imaging Science, Vanderbilt University, United States ; Department of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, United States ; Department of Electrical Engineering, Vanderbilt University, United States.
Mark D
MD
Does
G ratio; Histology; Hypomyelinated; MRI; Tuberous sclerosis