[Chemical Constituents from Leaves of Acanthus ilicifolius and Their Anti-influenza Virus Activities].
OBJECTIVE
To study the chemical constituents from the leaves of Acanthus ilicifolius.


METHODS
The compounds were isolated by silica and gel column chromatographic methods and identified by spectoscopic analysis. The anti-influenza virus activities of these compounds were obtained by measuring the neuraminidase activity of influenza virus.


RESULTS
Five compounds were isolated and their structures were identified as blepharin(1), acteoside(2), isoverbascoside(3), daucosterol(4), and 3-O-β-D-glucopyranosyl-stigmasterol(5).


CONCLUSIONS
All the compounds are isolated from the leaves of Acanthus ilicifolius for the first time, and compounds 1 ~ 3 exhibit the anti-influenza virus activities.
Yan-ping
YP
Chen
Dao-peng
DP
Tan
Qi
Q
Zeng
Yu
Y
Wang
Qi-xin
QX
Yan
Ling-jie
LJ
Zeng
D027901:Acanthaceae / Q000737:chemistry*; D000998:Antiviral Agents / Q000737:chemistry* / Q000302:isolation & purification; D005960:Glucosides; D009975:Orthomyxoviridae / Q000187:drug effects*; D010636:Phenols; D064209:Phytochemicals / Q000737:chemistry* / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry*; D012855:Sitosterols; D013265:Stigmasterol; D059808:Polyphenols
D000998:Antiviral Agents; D005960:Glucosides; D010636:Phenols; D064209:Phytochemicals; D012855:Sitosterols; D013265:Stigmasterol; C058956:acteoside; D059808:Polyphenols; C064683:isoacteoside; C011015:lyoniside