Peritoneal Malignant Mesothelioma with Epithelioid Type, Demonstrating High Serum and Ascitic KL-6 Levels: Immunohistochemical Analyses.
We report a case of KL-6 producing peritoneal malignant mesothelioma. A 56-year-old woman was referred to our hospital on November 2005 with severe abdominal distention. Peritoneal malignant mesothelioma with epithelioid type was diagnosed by clinical symptoms, laboratory investigations, imaging studies, and immunohistochemical examination of known tumor markers. In addition, high serum and ascitic KL-6 levels were observed and the immunostaining of the tumor for KL-6 was evident. We thus consider KL-6 to be a potential novel marker for peritoneal malignant mesothelioma with epithelioid type.
Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus , Nishihnara, Japan.
Saifun
S
Nahar
Department of Endoscopy, University of the Ryukyus , Nishihnara, Japan.
Manabu
M
Nakamoto
Department of Endoscopy, University of the Ryukyus , Nishihnara, Japan.
Akira
A
Hokama
Department of Endoscopy, University of the Ryukyus , Nishihnara, Japan.
Chiharu
C
Kobashigawa
Department of Endoscopy, University of the Ryukyus , Nishihnara, Japan.
Masatoshi
M
Kaida
Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus , Nishihnara, Japan.
Tetsu
T
Kinjo
Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus , Nishihnara, Japan.
Tetsuo
T
Hirata
Department of Endoscopy, University of the Ryukyus , Nishihnara, Japan.
Nagisa
N
Kinjo
Department of Pathology and Oncology, University of the Ryukyus , Nishihnara, Japan.
Masanao
M
Saio
Department of Pathology and Oncology, University of the Ryukyus , Nishihnara, Japan.
Naoki
N
Yoshimi
Division of Pathology, Matsuyama-shimin Hospital , Japan.
Yuji
Y
Ohtsuki
Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus , Nishihnara, Japan.
Jiro
J
Fujita
KL-6; Malignant mesothelioma; peritoneum