Acute coronary syndrome: a rare case of multiple endocrine neoplasia syndromes with pheochromocytoma and medullary thyroid carcinoma.
Pheochromocytoma is a tumor arising from neuroectodermal chromaffin tissues in the adrenal gland or extra-adrenal paraganglia (paragangliomas). The prevalence of the tumor is 0.1%-0.6% in the hypertensive population, of which 10%-20% are malignant. Pheochromocytoma produces, stores, and secretes catecholamines, as well as leads to hypertensive crisis, arrhythmia, angina, and acute myocardial infarction without coronary artery diseases. We report a case of acute coronary syndrome (ACS) with a final diagnosis of multiple endocrine neoplasia with pheochromocytoma and medullary thyroid carcinoma (MTC).
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Alessadro
A
Maloberti
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Paolo
P
Meani
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Roberto
R
Pirola
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Marisa
M
Varrenti
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Marco
M
Boniardi
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Anna Maria
AM
De Biase
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Paola
P
Vallerio
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Edgardo
E
Bonacina
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Giuseppe
G
Mancia
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Paola
P
Loli
1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.
Cristina
C
Giannattasio
Secondary hypertension; echocardiography; medullary thyroid carcinoma; multiple endocrine neoplasia; pheochromocytoma