The genomic landscape of adult T cell leukemia/lymphoma.
Adult T cell leukemia/lymphoma (ATL) is a neoplasm linked to human T-lymphotropic virus type-1 (HTLV-1) infection and is refractory to current combination chemotherapy. A large genomic and transcriptomic study of ATL now provides detailed insight into the molecular lesions implicated in the development of this T cell malignancy.
Center for Human Genetics, KU Leuven, Leuven, Belgium, and at the Center for the Biology of Disease, VIB, Leuven, Belgium.
Carmen
C
Vicente
Center for Human Genetics, KU Leuven, Leuven, Belgium, and at the Center for the Biology of Disease, VIB, Leuven, Belgium.
Jan
J
Cools
D019175:DNA Methylation; D059472:Exome / Q000235:genetics*; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*; D059467:Transcriptome / Q000235:genetics*