Endometriosis Under Estradiol Stimulation Imaged Using 18F-FDG and Its Control After Estradiol Cessation and Progesterone Hormonal Replacement.
Endometriosis is a frequent and benign cause of disabling abdominal pain, for which a diagnosis suspicion is clinically raised, but its confirmation necessitates a surgical exploration by laparoscopy. Foci of endometriosis proliferate under estrogen stimulation, like normal endometrium. We present a patient under estradiol stimulation for a history of endometrial cancer who underwent a PET/CT scan to assess an abdominal lesion showing a high F-FDG uptake, which normalized under progesterone hormonal replacement and cessation of estradiol. Two consecutive biopsies confirmed endometriosis. F-FDG evaluation of endometriosis under estrogen stimulation could be a promising approach to refractory endometriosis assessment.
From the *Department of Nuclear Medicine, Centre Hospitalier Universitaire de Montréal (CHUM), Hôpital Hôtel-Dieu de Montréal, Montréal; and †Sherbrooke Molecular Imaging Center (CIMS), Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.
Frédéric
F
Arsenault
Éric
É
Turcotte
D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D004715:Endometriosis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D004958:Estradiol / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D019788:Fluorodeoxyglucose F18; D020249:Hormone Replacement Therapy; D006801:Humans; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011374:Progesterone / Q000008:administration & dosage / Q000627:therapeutic use; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D011374:Progesterone; D004958:Estradiol