A Convenient Palladium-Catalyzed Carbonylative Suzuki Coupling of Aryl Halides with Formic Acid as the Carbon Monoxide Source.
A practical palladium-catalyzed carbonylative Suzuki coupling of aryl halides under carbon monoxide gas-free conditions has been developed. Here, formic acid was utilized as the carbon monoxide source for the first time with acetic anhydride as the additive. A variety of diarylketones were produced in moderate to excellent yields from the corresponding aryl halides and arylboronic acids.
Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018 (P.R. China).
Xinxin
X
Qi
Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018 (P.R. China).
Li-Bing
LB
Jiang
Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018 (P.R. China).
Hao-Peng
HP
Li
Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou 310018 (P.R. China). xiao-feng.wu@catalysis.de.|Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock (Germany). xiao-feng.wu@catalysis.de.
Xiao-Feng
XF
Wu
carbonylation; cross-coupling; heterogeneous catalysis; palladium; synthesis design