Molecular weight-gyration radius relation of globular proteins: a comparison of light scattering, small-angle X-ray scattering and structure-based data.
The molecular weight-gyration radius relation for a number of globular proteins based on experimental light scattering data is compared with small-angle X-ray scattering data recently published by Mylonas & Svergun [J. Appl. Cryst.(2007 ▸),40, s245-s249]. In addition, other recent experimental data and theoretical calculations are reviewed. It is found that theMW-Rgrelation for the globular proteins is well represented by a power law with an exponent of 0.37 (2).
CHESS, Cornell University , Ithaca, NY 14850, USA.
Detlef-M
DM
Smilgies
W. M. Keck Biophysical Resource Laboratory, Yale School of Medicine , New Haven, CT 06511, USA.
Ewa
E
Folta-Stogniew
globular proteins; light scattering; radius of gyration; small-angle scattering