Cutaneous asthenia (Ehlers-Danlos-like syndrome) of Burmese cats.
A 6-month-old Burmese kitten developed focal skin lesions following a routine ovariohysterectomy. These were eventually attributed to the patient struggling during catheter placement and induction of anaesthesia. The lesions were caused by fluid extravasation in the subcutis and ischaemic necrosis of the overlying dermis, giving rise to an eschar-like appearance. Such lesions have been seen previously in Burmese cats with cutaneous asthenia and it is thought that they arise due to poor collagenous support for dermal blood vessels. An increased skin extensibility index (>23%) supported a diagnosis of cutaneous asthenia (Ehlers-Danlos-like syndrome), which has been reported as an inherited condition of Burmese cats in Australia, New Zealand and Europe. An additional Burmese cat with cutaneous asthenia is presented in detail, with lifetime follow-up and further salient observations by the owner, a veterinarian. Photographs of three other affected Burmese cats are provided to illustrate the range of presentations encountered with this condition. All five affected cats were presented with eschars, atrophic alopecia and increased skin extensibility, while one cat also had skin ulcers. Routine histopathological examination, including use of special stains such as trichrome, was unhelpful in establishing the diagnosis.
The clinical features of this genetic disease of Burmese cats are reviewed, especially in relation to the postulated 'vasculopathy' that gives rise to characteristic skin lesions. Long term management of this condition is discussed briefly.
Greencross Noosa Veterinary Clinic, 15 Hilton Terrace, Tewantin, QLD 4565, Australia.
Naomi
N
Hansen
Vetnostics, 60 Waterloo Rd, North Ryde, NSW 2060, Australia.
Susan F
SF
Foster
Murdoch University Veterinary Teaching Hospital, Murdoch, WA, Australia.
Amanda K
AK
Burrows
Vepalabs, 36 Balaclava St, Woolloongabba, QLD 4102, Australia.
John
J
Mackie
Centre for Veterinary Education, Building B22, The University of Sydney, NSW 2006, Australia richard.malik@sydney.edu.au.
Richard
R
Malik
D000758:Anesthesia / Q000009:adverse effects* / Q000662:veterinary; D000818:Animals; D001247:Asthenia / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis* / Q000209:etiology*; D002415:Cats; D004535:Ehlers-Danlos Syndrome / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D005260:Female; D010052:Ovariectomy / Q000009:adverse effects; D012867:Skin / Q000473:pathology