Differential relationships between chronic hormone profiles in pregnancy and maternal investment in rhesus monkey mothers with hair loss in the neonatal period.
Hair loss is commonly used as an indicator of well being in primate facilities, yet it has been shown to also occur in otherwise healthy pregnant and postpartum females. There is significant variability in the incidence of hair loss during these important developmental periods, reasons for which remain unclear. We studied female rhesus monkeys (Macaca mulatta, n = 47) with and without hair loss in pregnancy/postpartum. We hypothesized that, similar to previously published reports, pregnancy would result in an increased likelihood of hair loss, and that hair loss would be correlated with higher hair cortisol concentrations (HCCs). We further hypothesized that hair loss among pregnant females is related to differential maternal investment. We studied a subset of monkeys (n = 26) from mid-to-late pregnancy through peak lactation, some of which exhibited hair loss in the perinatal period (n = 15), and some of which did not (n = 11). We examined fetal measurements, infant birth weight, infant growth rate, and milk yield volume (MYV) in the first 30 days as indices of investment. We found that pregnant monkeys showed a greater incidence of hair loss across the study year (χ2(2)= 6.55, P = 0.038), and that mothers with hair loss had significantly higher HCCs in pregnancy than those without (F(2,28)= 3.8, P = 0.017, ηp2= 0.21). HCCs in pregnancy were correlated with severity of hair loss in the neonatal period (r(37)= 0.42, P = 0.008). Moreover, HCCs in pregnancy were positively correlated with infant birth weight (r(12)= 0.56, P = 0.038), infant growth rate (r(12)= 0.64, P = 0.014), and MYV (r(11)= 0.85, P < 0.001) for alopecic but not non-alopecic mothers. These mothers did not differ in fetal measurements, infant birth weight/growth rate, or MYV. Our results suggest that hair loss in some monkeys, especially during the birthing season, may be a signal of greater physiological stress during pregnancy and differential investment by mothers to their offspring. Am. J. Primatol. 79:e22489, 2017. © 2015 Wiley Periodicals, Inc.
Laboratory of Comparative Ethology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Poolesville, Maryland.
Amanda M
AM
Dettmer
Department of Psychology, University of Massachusetts Amherst, Amherst, Massachusetts.
Kendra
K
Rosenberg
Department of Psychology, University of Massachusetts Amherst, Amherst, Massachusetts.
Mark T
MT
Menard
Department of Psychology, University of Massachusetts Amherst, Amherst, Massachusetts.
Saif N
SN
El-Mallah
Research Animal Management Branch, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Poolesville, Maryland.
Ruth A
RA
Woodward
Laboratory of Comparative Ethology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Poolesville, Maryland.
Stephen J
SJ
Suomi
Department of Psychology, University of Massachusetts Amherst, Amherst, Massachusetts.
Jerrold S
JS
Meyer
D000505:Alopecia / Q000662:veterinary*; D000818:Animals; D005260:Female; D006197:Hair; D007774:Lactation; D008253:Macaca mulatta; D009035:Mothers; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*
alopecia; hair loss; infant growth; maternal investment; pregnancy