Evaluation of the effects of silicone implants on the breast parenchyma.
BACKGROUND
Despite being the cosmetic procedure most performed worldwide, there are still few objective measurements of postoperative volumetric analysis of breast augmentation available in the literature.


OBJECTIVE
The aim of this study was to evaluate volumetric changes in the breast parenchyma after the placement of silicone implants in the subglandular plane.


METHODS
Thirty-four women were randomly allocated to the intervention group (n = 24), who underwent breast augmentation in the subglandular plane, or to the control group (n = 10), who received no intervention. Volumetric magnetic resonance imaging was performed at inclusion, and after 6 and 12 months in all participants. The non-parametric Friedman's test was used for statistical analysis.


RESULTS
There was a significant reduction in glandular volume (mean, 22%) at 12 months postoperatively in patients who underwent breast augmentation.


CONCLUSIONS
Breast augmentation caused reduction in the volume of the breast parenchyma.


METHODS
3 Therapeutic.
Dr Roxo is a PhD Student, Graduate Program in Physiopathology and Surgical Sciences, and Drs Nahas, de Castro, and Aboudib are Associate Professors, Division of Plastic and Reconstructive Surgery, "Pedro Ernesto" University Hospital, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil. Dr Bazi is a Radiologist, Breast Division, Rio Imagem Center for Diagnostic Imaging of the State of Rio de Janeiro, Rio de Janeiro, Brazil. Dr Marques is an Assistant Professor, Graduate Program in Physiopathology and Surgical Sciences, Department of General Surgery, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.
Ana Claudia Weck
AC
Roxo
Dr Roxo is a PhD Student, Graduate Program in Physiopathology and Surgical Sciences, and Drs Nahas, de Castro, and Aboudib are Associate Professors, Division of Plastic and Reconstructive Surgery, "Pedro Ernesto" University Hospital, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil. Dr Bazi is a Radiologist, Breast Division, Rio Imagem Center for Diagnostic Imaging of the State of Rio de Janeiro, Rio de Janeiro, Brazil. Dr Marques is an Assistant Professor, Graduate Program in Physiopathology and Surgical Sciences, Department of General Surgery, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.
Fabio Xerfan
FX
Nahas
Dr Roxo is a PhD Student, Graduate Program in Physiopathology and Surgical Sciences, and Drs Nahas, de Castro, and Aboudib are Associate Professors, Division of Plastic and Reconstructive Surgery, "Pedro Ernesto" University Hospital, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil. Dr Bazi is a Radiologist, Breast Division, Rio Imagem Center for Diagnostic Imaging of the State of Rio de Janeiro, Rio de Janeiro, Brazil. Dr Marques is an Assistant Professor, Graduate Program in Physiopathology and Surgical Sciences, Department of General Surgery, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.
Fernanda
F
Bazi
Dr Roxo is a PhD Student, Graduate Program in Physiopathology and Surgical Sciences, and Drs Nahas, de Castro, and Aboudib are Associate Professors, Division of Plastic and Reconstructive Surgery, "Pedro Ernesto" University Hospital, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil. Dr Bazi is a Radiologist, Breast Division, Rio Imagem Center for Diagnostic Imaging of the State of Rio de Janeiro, Rio de Janeiro, Brazil. Dr Marques is an Assistant Professor, Graduate Program in Physiopathology and Surgical Sciences, Department of General Surgery, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.
Claudio Cardoso
CC
de Castro
Dr Roxo is a PhD Student, Graduate Program in Physiopathology and Surgical Sciences, and Drs Nahas, de Castro, and Aboudib are Associate Professors, Division of Plastic and Reconstructive Surgery, "Pedro Ernesto" University Hospital, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil. Dr Bazi is a Radiologist, Breast Division, Rio Imagem Center for Diagnostic Imaging of the State of Rio de Janeiro, Rio de Janeiro, Brazil. Dr Marques is an Assistant Professor, Graduate Program in Physiopathology and Surgical Sciences, Department of General Surgery, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.
Jose Horacio
JH
Aboudib
Dr Roxo is a PhD Student, Graduate Program in Physiopathology and Surgical Sciences, and Drs Nahas, de Castro, and Aboudib are Associate Professors, Division of Plastic and Reconstructive Surgery, "Pedro Ernesto" University Hospital, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil. Dr Bazi is a Radiologist, Breast Division, Rio Imagem Center for Diagnostic Imaging of the State of Rio de Janeiro, Rio de Janeiro, Brazil. Dr Marques is an Assistant Professor, Graduate Program in Physiopathology and Surgical Sciences, Department of General Surgery, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.
Ruy Garcia
RG
Marques
D000293:Adolescent; D000328:Adult; D001938:Brazil; D001940:Breast / Q000033:anatomy & histology*; D019928:Breast Implantation / Q000009:adverse effects / Q000379:methods*; D018427:Breast Implants / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000379:methods; D008327:Mammography / Q000379:methods; D009929:Organ Size / Q000502:physiology; D011300:Preoperative Care / Q000379:methods; D011446:Prospective Studies; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012016:Reference Values; D018570:Risk Assessment; D020034:Silicone Gels / Q000009:adverse effects / Q000494:pharmacology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult
D020034:Silicone Gels