Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature.
OBJECTIVE
We report the results of the intralesional steroid injections for the management of central giant cell granuloma (CGCG) of the jaws.


METHODS
Seven CGCGs were treated with intralesional injection of corticosteroids. To accomplish this, 3.5 mL of triamcinolone and 3.5 mL of 0.5 % marcaine with 1/200,000 epinephrine (total 7 mL) were mixed. An adequate amount of steroid was injected into different areas of the lesion. This procedure was repeated on a weekly basis for 6 weeks.


RESULTS
Clinical and radiological examination showed complete resolution and ossification of the lesions in four patients. Partial recovery was achieved in two patients. One patient did not respond to the treatment and underwent surgical curettage.


CONCLUSIONS
We suggest that intralesional steroid injection is safe and effective for the treatment of CGCG, especially in non-aggressive lesions.
Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Selçuk University, Konya, Turkey.
Doğan
D
Dolanmaz
Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Necmettin Erbakan University, Ankara Cd. No:75/A, Konya, Turkey. dtaesen@hotmail.com.
Alparslan
A
Esen
Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Bezmialem University, Istanbul, Turkey.
Ahmet
A
Mihmanlı
Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Necmettin Erbakan University, Konya, Turkey.
Kubilay
K
Işık
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D004837:Epinephrine / Q000008:administration & dosage*; D006101:Granuloma, Giant Cell / Q000188:drug therapy*; D006801:Humans; D015552:Injections, Intralesional; D007571:Jaw Diseases / Q000188:drug therapy*; D019233:Retreatment; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
D000305:Adrenal Cortex Hormones; D004338:Drug Combinations; D014222:Triamcinolone Acetonide; D002045:Bupivacaine; D004837:Epinephrine
Corticosteroid; Giant cell granuloma; Intralesional injections; Triamcinolone acetonide