Central retinal vein occlusion in an otherwise healthy child treated successfully with a single injection of bevacizumab.
We describe the case of an otherwise healthy 13-year-old boy who presented with blurred vision and deteriorating visual acuity in his left eye. Fundus examination showed left optic disk swelling, exudates, and hemorrhages. He was found to have an elevated left central retinal venous pressure to the level of arterial diastolic pressure, an elevated left central macular thickness and a prolonged disk-to-disk transit time on fluorescein angiography, which confirmed the diagnosis of unilateral central retinal vein occlusion (CRVO). The child was treated with one injection of bevacizumab. He has maintained visual acuity of 6/6 for 2 years following treatment, despite persistent elevated left central venous pressure and chronic optic disk edema.
The Children's Hospital at Westmead, Sydney Medical School, University of Sydney, Sydney, Australia. Electronic address: lindazhengs@gmail.com.
Linda
L
Zheng
Save Sight Institute, Sydney Medical School, University of Sydney, Sydney, Australia; Eye Associates, Park House, Macquarie Street, Sydney, Australia.
Mark
M
Gillies
The Children's Hospital at Westmead, Sydney Medical School, University of Sydney, Sydney, Australia.
Frank J
FJ
Martin
D000293:Adolescent; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D000068258:Bevacizumab / Q000627:therapeutic use*; D005451:Fluorescein Angiography; D006801:Humans; D058449:Intravitreal Injections; D008279:Magnetic Resonance Imaging; D008297:Male; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D014057:Tomography, X-Ray Computed; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors; D014792:Visual Acuity / Q000187:drug effects
D020533:Angiogenesis Inhibitors; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D000068258:Bevacizumab