Aggregates of a cationic porphyrin as supramolecular probes for biopolymers.
The copper(II) derivative of the dicationic trans-bis(N-methylpyridinium-4-yl)diphenylporphyrin (t-CuPagg) forms large fractal aggregates in aqueous solution under moderate ionic strength conditions. A kinetic investigation of the aggregation process allows for a choice of experimental conditions to quickly obtain stable assemblies in solution. These positively charged aggregates are able to interact efficiently with negatively charged chiral species, (including bacterial spores) leading to induced circular dichroism signals in the Soret region of the porphyrin, now acting as a sensitive chiroptical probe.
Dipartimento di Scienze Chimiche, Via Marzolo 1, 35131 Padova, Italy.
Ilaria Giuseppina
IG
Occhiuto
Dipartimento di Scienze Chimiche and C.I.R.C.M.S.B., V.le F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Mario
M
Samperi
Istituto per lo Studio dei Materiali Nanostrutturati ISMN-CNR c/o Dipartimento di Scienze Chimiche, University of Messina, V.le F. Stagno D'Alcontres, 31-98166 Messina, Italy.
Mariachiara
M
Trapani
Dipartimento di Scienze del Farmaco e dei Prodotti per la Salute, V.le Annunziata, 98168 Messina, Italy.
Giovanna
G
De Luca
Dipartimento di Scienze Chimiche and C.I.R.C.M.S.B., V.le F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Andrea
A
Romeo
Department of Chemistry & Biochemistry, Swarthmore College, 500 College Avenue, Swarthmore, PA 19081, USA.
Robert F
RF
Pasternack
Dipartimento di Scienze Chimiche and C.I.R.C.M.S.B., V.le F. Stagno d'Alcontres 31, 98166 Messina, Italy; Istituto per lo Studio dei Materiali Nanostrutturati ISMN-CNR c/o Dipartimento di Scienze Chimiche, University of Messina, V.le F. Stagno D'Alcontres, 31-98166 Messina, Italy. Electronic address: lmonsu@unime.it.
Luigi Monsù
LM
Scolaro
D056831:Coordination Complexes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D003300:Copper / Q000737:chemistry*; D007536:Isomerism; D011166:Porphyrins / Q000737:chemistry*; D012965:Sodium Chloride / Q000737:chemistry; D013171:Spores, Bacterial / Q000187:drug effects; D055672:Static Electricity
D056831:Coordination Complexes; D011166:Porphyrins; D012965:Sodium Chloride; D003300:Copper
Chirality; Chiroptical sensor; Circular dichroism; Porphyrin; Supramolecular aggregate