Nanotechnology in dentistry: prevention, diagnosis, and therapy.
Nanotechnology has rapidly expanded into all areas of science; it offers significant alternative ways to solve scientific and medical questions and problems. In dentistry, nanotechnology has been exploited in the development of restorative materials with some significant success. This review discusses nanointerfaces that could compromise the longevity of dental restorations, and how nanotechnolgy has been employed to modify them for providing long-term successful restorations. It also focuses on some challenging areas in dentistry, eg, oral biofilm and cancers, and how nanotechnology overcomes these challenges. The recent advances in nanodentistry and innovations in oral health-related diagnostic, preventive, and therapeutic methods required to maintain and obtain perfect oral health, have been discussed. The recent advances in nanotechnology could hold promise in bringing a paradigm shift in dental field. Although there are numerous complex therapies being developed to treat many diseases, their clinical use requires careful consideration of the expense of synthesis and implementation.
Division of Biomaterials, Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia ; Biomaterials Department, Faculty of Dentistry, Tanta University, Tanta, Egypt ; UCL Eastman Dental Institute, Biomaterials and Tissue Engineering, London, UK.
Ensanya Ali
EA
Abou Neel
UCL Eastman Dental Institute, Biomaterials and Tissue Engineering, London, UK.
Laurent
L
Bozec
Institute of Tissue Regenerative Engineering (ITREN), Dankook University, Cheonan, Republic of Korea ; Department of Nanobiomedical Science and BK21 Plus NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, Republic of Korea.
Roman A
RA
Perez
Institute of Tissue Regenerative Engineering (ITREN), Dankook University, Cheonan, Republic of Korea ; Department of Nanobiomedical Science and BK21 Plus NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, Republic of Korea ; Department of Biomaterials Science, College of Dentistry, Dankook University, Cheonan, Republic of Korea.
Hae-Won
HW
Kim
UCL Eastman Dental Institute, Biomaterials and Tissue Engineering, London, UK ; Department of Nanobiomedical Science and BK21 Plus NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, Republic of Korea.
Jonathan C
JC
Knowles
D000818:Animals; D003813:Dentistry / Q000379:methods*; D019937:Diagnostic Techniques and Procedures; D006801:Humans; D036103:Nanotechnology / Q000379:methods*; D011313:Preventive Dentistry; D013812:Therapeutics
biofilm-related oral diseases; drug delivery; nanointerfaces; nanotechnology; tissue engineering; toxicity