Is It Better to Be Rich or Relaxed? Sociobiology Meets Bone Marrow Transplant.
Low socioeconomic status in hematopoietic cell transplant recipients is associated with increased treatment-related mortality and relapse, resulting in reduced survival. No biologic mechanism has been identified for these associations. The stress-related gene expression profile, termed the "conserved transcriptional response to adversity," may be a predictor of these negative outcomes.
Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.
Lucie M
LM
Turcotte
Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota. verneris@umn.edu.
Michael R
MR
Verneris
D016026:Bone Marrow Transplantation; D002908:Chronic Disease; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D012008:Recurrence; D035503:Sociobiology