Surface-enhanced Raman scattering imaging of cancer cells and tissues via sialic acid-imprinted nanotags.
Molecularly imprinted nanoparticles were prepared as surface-enhanced Raman scattering tags for the selective imaging of cancer cells and tissues against normal cells and tissues relying on the use of sialic acid-templated imprinting to recognize cancer cells, which are over-expressed with sialic acid at the surface.
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing 210093, China. zhenliu@nju.edu.cn.
Danyang
D
Yin
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing 210093, China. zhenliu@nju.edu.cn.
Shuangshou
S
Wang
The Comprehensive Cancer Center of Drum Tower Hospital, Clinical College of Nanjing Medical University, Zhongshan Road 321, Nanjing 21008, China.
Yunjie
Y
He
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing 210093, China. zhenliu@nju.edu.cn.
Jia
J
Liu
Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.
Min
M
Zhou
Department of Hematology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.
Jian
J
Ouyang
The Comprehensive Cancer Center of Drum Tower Hospital, Clinical College of Nanjing Medical University, Zhongshan Road 321, Nanjing 21008, China.
Baorui
B
Liu
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing 210093, China. zhenliu@nju.edu.cn.
Hong-Yuan
HY
Chen
State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, 22 Hankou Road, Nanjing 210093, China. zhenliu@nju.edu.cn.
Zhen
Z
Liu
D000814:Aniline Compounds / Q000737:chemistry; D001547:Benzaldehydes / Q000737:chemistry; D001897:Boronic Acids / Q000737:chemistry; D056945:Hep G2 Cells; D006801:Humans; D008113:Liver Neoplasms; D053768:Metal Nanoparticles / Q000737:chemistry*; D054802:Molecular Imprinting / Q000379:methods*; D019158:N-Acetylneuraminic Acid / Q000737:chemistry*; D011437:Propylamines; D012821:Silanes / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013059:Spectrum Analysis, Raman; D013438:Sulfhydryl Compounds / Q000737:chemistry
C000611982:4-formylphenylboronic acid; D000814:Aniline Compounds; D001547:Benzaldehydes; D001897:Boronic Acids; D011437:Propylamines; D012821:Silanes; D013438:Sulfhydryl Compounds; D012834:Silver; C040733:tetraethoxysilane; C064316:4-aminothiophenol; D019158:N-Acetylneuraminic Acid; C477625:amino-propyl-triethoxysilane