Analysis on the risk factors of intracranial infection secondary to traumatic brain injury.
OBJECTIVE
To discuss the characteristics and risk factors for intracranial infection post traumatic brain injury to prevent and better the clinical care.


METHODS
Retrospective study of 520 patients with traumatic brain injury were included, 308 male and 212 female. The risky factors of intracranial infection were identified.


RESULTS
Thirty two cases (6.54%, 32/520) of intracranial infection were diagnosed. Intracranial infection most likely happened 4-10 days after injury. Cerebrospinal fluid leakage, drainage, multiple craniotomies were significant related to intracranial infection. Logistic regression predicted cerebrospinal fluid leakage and drainage as independent factors.


CONCLUSIONS
Intracranial infection is a serious complication after traumatic brain injury. Patients with drainage or cerebrospinal fluid leakage are more risky for intracranial infection. Aggressive precaution should be taken to better outcome.
Department of Neurosurgery, Jinling Hospital, Nanjing University, China.
Chao
C
Lin
Xin
X
Zhao
Haichen
H
Sun
D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000209:etiology*; D000070642:Brain Injuries, Traumatic / Q000150:complications*; D020806:Central Nervous System Bacterial Infections / Q000209:etiology*; D065634:Cerebrospinal Fluid Leak / Q000150:complications; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors