[IMMUNOMODULATORY ACTIVITY OF NEW GALACTOSE-CONTAING POLYSACCHARIDES].
The immunomodulatory properties of perspective prebiotics--beta-galactose-containing--polysaccharides arabinogalactan, arabinogalactan with flavonoids, carrageenan, galaktomannan have been studied. It was established that oral administration of the studied beta-polysaccharides to experimental animals leads to a significant activation of immune cells and the synthesis of humoral factors in their organism which significantly increases the cytotoxic activity of blood serum. The most pronounced immunomodulatory effect exhibits arabinogalactan with flavonoids and carrageenan.
L A
LA
Safronova
G V
GV
Didenko
V S
VS
Podgorsky
B G
BG
Sukhov
Yu P
YP
Dzhioev
D000818:Animals; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology; D005685:Galactans / Q000737:chemistry / Q000494:pharmacology; D005690:Galactose / Q000737:chemistry / Q000494:pharmacology* / Q000031:analogs & derivatives; D007155:Immunologic Factors / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology; D008351:Mannans / Q000737:chemistry / Q000494:pharmacology; D008807:Mice, Inbred BALB C; D011134:Polysaccharides / Q000737:chemistry / Q000494:pharmacology*; D056692:Prebiotics
D005419:Flavonoids; D005685:Galactans; D007155:Immunologic Factors; D008351:Mannans; D011134:Polysaccharides; D056692:Prebiotics; C012990:galactomannan; D005690:Galactose