Visible-Light-Induced Direct Photocatalytic Carboxylation of Indoles with CBr4 /MeOH.
Photocatalysis enables the cascade reactions of indoles and CBr4 in MeOH through a C(sp(2) )H functionalization/methanolysis sequence. The title reaction provides an efficient access to indole 2- and 3-carboxylates in a single operation (no preinstallation of protecting as well as directing groups was required) with good yields under mild reaction conditions.
Department of Chemistry "G. Ciamician", Alma Mater Studiorum, University of Bologna, Via Selmi 2, 40126 Bologna (Italy) http://www.mbandini-group.com.|Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University (CCNU), 152 Luoyu Road, Wuhan, Hubei 430079 (China).
Qing-Qing
QQ
Yang
Department of Chemistry "G. Ciamician", Alma Mater Studiorum, University of Bologna, Via Selmi 2, 40126 Bologna (Italy) http://www.mbandini-group.com.
Marianna
M
Marchini
Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University (CCNU), 152 Luoyu Road, Wuhan, Hubei 430079 (China).
Wen-Jing
WJ
Xiao
Department of Chemistry "G. Ciamician", Alma Mater Studiorum, University of Bologna, Via Selmi 2, 40126 Bologna (Italy) http://www.mbandini-group.com. paola.ceroni@unibo.it.
Paola
P
Ceroni
Department of Chemistry "G. Ciamician", Alma Mater Studiorum, University of Bologna, Via Selmi 2, 40126 Bologna (Italy) http://www.mbandini-group.com. marco.bandini@unibo.it.
Marco
M
Bandini
carboxylation; indole functionalization; methanolysis; photocatalysis; visible light