Surface-Specific Functionalization of Nanoscale Metal-Organic Frameworks.
A method for modifying the external surfaces of a series of nanoscale metal-organic frameworks (MOFs) with 1,2-dioleoyl-sn-glycero-3-phosphate (DOPA) is presented. A series of zirconium-based nanoMOFs of the same topology (UiO-66, UiO-67, and BUT-30) were synthesized, isolated as aggregates, and then conjugated with DOPA to create stably dispersed colloids. BET surface area analysis revealed that these structures maintain their porosity after surface functionalization, providing evidence that DOPA functionalization only occurs on the external surface. Additionally, dye-labeled ligand loading studies revealed that the density of DOPA on the surface of the nanoscale MOF correlates to the density of metal nodes on the surface of each MOF. Importantly, the surface modification strategy described will allow for the general and divergent synthesis and study of a wide variety of nanoscale MOFs as stable colloidal materials.
Department of Chemistry, Northwestern University, Evanston, IL (USA).
Shunzhi
S
Wang
International Institute for Nanotechnology, Northwestern University, Evanston, IL (USA).
William
W
Morris
Department of Chemistry, Northwestern University, Evanston, IL (USA).
Yangyang
Y
Liu
Department of Chemistry, Northwestern University, Evanston, IL (USA).
C Michael
CM
McGuirk
Department of Material Science and Engineering, Northwestern University, Evanston, IL (USA).
Yu
Y
Zhou
Department of Chemistry, Northwestern University, Evanston, IL (USA).
Joseph T
JT
Hupp
Department of Chemistry, Northwestern University, Evanston, IL (USA).|Department of Chemistry, King Abdulaziz University, Jeddah (Saudi Arabia).
Omar K
OK
Farha
Department of Chemistry, Northwestern University, Evanston, IL (USA). chadnano@northwestern.edu.|International Institute for Nanotechnology, Northwestern University, Evanston, IL (USA). chadnano@northwestern.edu.|Department of Material Science and Engineering, Northwestern University, Evanston, IL (USA). chadnano@northwestern.edu.
Chad A
CA
Mirkin
metal-organic frameworks; phosphate lipids; post-synthetic modification; surface functionalization; zirconium oxo clusters