Update on Clinical Magnetic Resonance-Guided Focused Ultrasound Applications.
In this review, several clinical applications of magnetic resonance (MR)-guided focused ultrasound (FUS) are updated. MR-guided FUS is used clinically for thermal ablation of uterine fibroids and bone metastases. Thousands of patients have successfully been treated. Transcranial MR-guided FUS has received CE certification for ablation of deep, central locations in the brain. Thermal ablation of specific parts of the thalamus can result in relief of the symptoms in a number of neurological disorders. Several approaches have been proposed for ablation of prostate and breast cancer and clinical trials should show the potential of MR-guided FUS for these and other applications.
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, #521, Boston, MA 02115, USA; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Geert Grooteplein 10, 6500 HB, Nijmegen, Netherlands. Electronic address: tkobus@partners.org.
Thiele
T
Kobus
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue, #521, Boston, MA 02115, USA.
Nathan
N
McDannold
D005260:Female; D006801:Humans; D053783:Magnetic Resonance Imaging, Interventional; D008297:Male; D014464:Ultrasonic Therapy
Bone metastasis pain management; Brain disease; Breast cancer; Focused ultrasound; MR imaging; Thermal ablation prostate cancer; Uterine fibroids