The beneficial effects of honeybee-venom serum on facial wrinkles in humans.
Facial wrinkles are an undesirable outcome caused by extrinsic photodamage and intrinsic aging processes. Currently, no effective strategies are known to prevent facial wrinkles. We assessed the beneficial effects of bee-venom serum on the clinical signs of aging skin. Our results show that bee-venom serum treatment clinically improved facial wrinkles by decreasing total wrinkle area, total wrinkle count, and average wrinkle depth. Therefore, bee-venom serum may be effective for the improvement of skin wrinkles.
Department of Agricultural Biology, National Academy of Agricultural Science, Wanju, South Korea.
Sang Mi
SM
Han
Department of Agricultural Biology, National Academy of Agricultural Science, Wanju, South Korea.
In Phyo
IP
Hong
Department of Agricultural Biology, National Academy of Agricultural Science, Wanju, South Korea.
Soon Ok
SO
Woo
Dong Sung Pharmaceuticals Co Ltd, Seoul, South Korea.
Sung Nam
SN
Chun
Department of Pathology, School of Medicine, Catholic University of Daegu, Daegu, South Korea.
Kwan Kyu
KK
Park
Manuka Doctor Ltd, Auckland, New Zealand.
Young Mee
YM
Nicholls
School of Biomedical Sciences, Charles Sturt University, Bathurst, NSW, Australia.
Sok Cheon
SC
Pak
D000328:Adult; D000818:Animals; D001514:Bee Venoms / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D056910:Republic of Korea; D015595:Skin Aging / Q000187:drug effects*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
D001514:Bee Venoms
area; bee venom; count; depth; wrinkle