Hepatic ethoxyresorufin-O-deethylase induction in the common kingfisher from an electronic waste recycling site.
The health effects of exposure to electronic waste (e-waste)-derived pollutants are an important issue. The authors explored the association between the hepatic levels of e-waste-derived halogenated contaminants (including polychlorinated biphenyls [PCBs], polybrominated diphenyl ethers [PBDEs], and polybrominated biphenyls [PBBs]) and hepatic ethoxyresorufin-O-deethylase (EROD) activity of the common kingfisher (Alcedo atthis) from an e-waste site and 2 reference sites in South China. The summed concentrations of PCBs, PBDEs, and PBBs ranged from 620 ng/g to 15 000 ng/g, 25 ng/g to 900 ng/g, and 14 ng/g to 49 ng/g wet weight, respectively, in the kingfishers from the e-waste site, and these values were significantly greater (2-3 orders of magnitude) than those obtained at the 2 reference sites. Correspondingly, significant hepatic EROD induction was observed in the kingfishers from the e-waste site compared with the reference sites. The EROD activity was significantly correlated to the levels of most of the PCB and PBDE congeners examined as well as PBB 153, suggesting that EROD induction may be evoked by these e-waste-derived pollutants. Environ Toxicol Chem 2016;35:1594-1599. © 2015 SETAC.
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, China.
Jiang-Ping
JP
Wu
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, China.|Hainan Research Academy of Environmental Sciences, Haikou, China.
Ling
L
Mo
The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Hui
H
Zhi
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, China.
Ying
Y
Peng
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, China.
Lin
L
Tao
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, China.
Zi-He
ZH
Ren
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, China.
Xiao-Jun
XJ
Luo
State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Resources Utilization and Protection, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou, China.
Bi-Xian
BX
Mai
D000818:Animals; D001717:Birds / Q000378:metabolism*; D002681:China; D019363:Cytochrome P-450 CYP1A1 / Q000378:metabolism*; D059029:Electronic Waste / Q000032:analysis*; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000032:analysis / Q000633:toxicity; D008401:Gas Chromatography-Mass Spectrometry; D055768:Halogenated Diphenyl Ethers / Q000032:analysis / Q000633:toxicity; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D011075:Polybrominated Biphenyls / Q000032:analysis / Q000633:toxicity; D011078:Polychlorinated Biphenyls / Q000032:analysis / Q000633:toxicity; D059027:Recycling
D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; D011075:Polybrominated Biphenyls; D011078:Polychlorinated Biphenyls; D019363:Cytochrome P-450 CYP1A1
Bird; Ethoxyresorufin-O-deethylase (EROD); Flame retardants; Polybrominated diphenyl ethers (PBDEs); Polychlorinated biphenyls (PCBs)