Decellular Nerve Allografts.
Multiple treatment options are available for patients who have peripheral nerve injuries with a gap. Decellular nerve allografts are one option and provide an extracellular scaffold for neuronal cells to migrate for axonal regrowth. Immunosuppression is not needed because improved nerve processing technologies have rendered decellular nerve allografts nonimmunogenic. These allografts have also shown promising results in both animal and human studies as an alternative repair option.
Peter
P
Tang
Aakash
A
Chauhan
D064591:Allografts / Q000637:transplantation*; D000818:Animals; D006801:Humans; D007165:Immunosuppression Therapy; D016067:Nerve Transfer / Q000379:methods*; D059348:Peripheral Nerve Injuries / Q000601:surgery*; D014184:Transplantation, Homologous / Q000379:methods
Peripheral nerve injury; acellular nerve allograft; decellular nerve allograft; regeneration; repair