Periodontal Treatment Elevates Carotid Wall Shear Stress in the Medium Term.
Periodontal disease is associated with endothelial dysfunction of the brachial artery and hemodynamic alterations of the common carotid artery. Periodontal therapy improves endothelial function. It is not known if it is able also to improve the hemodynamics of the carotid artery. The aim of the current study was to evaluate the efficacy of 2 different periodontal treatments on carotid hemodynamics: scaling and root planing (SRP) alone or together with low-level laser therapy (LLLT). Forty patients were recruited and randomly treated with SRP (n = 20) or SRP + LLLT (n = 20). Periodontal indices (plaque, gingival, and probing depth indices) were measured before and 5 months after treatment. Blood viscosity, common carotid wall shear stress, circumferential wall tension, and Peterson elastic modulus were evaluated before, soon after and 5 months after treatment. It was found that the periodontal indices improved in both groups, but significantly more so for SRP + LLLT than for SRP (decrease in gingival index 69.3% versus 45.4%, respectively, P = 0.04). In the SRP + LLLT group, after a transient reduction by 5% immediately after therapy, shear stress increased by 11% after 5 months. In SRP only group, however, shear stress variations were less marked. No significant changes were found for the other hemodynamic parameters in either of the groups. Periodontal disease treatment by SRP + LLLT can therefore be said to improve common carotid wall shear stress. This suggests a possible mechanism by which the treatment of periodontal disease has beneficial effects on the cardiovascular system.
From the Department of Chemical Engineering, Imperial College London, London, United Kingdom (CC, SC); Department of Clinical and Experimental Medicine, Institute of Dentistry, "Magna Graecia" University (MSDF, CI, AG, AC, MF, LF); and Department of Clinical and Experimental Medicine, Metabolic Disease Unit, "Magna Graecia" University, Catanzaro, Italy (CC, MSDF, CT, CI, AG).
Claudio
C
Carallo
Maria Serena De
MS
Franceschi
Cesare
C
Tripolino
Claudio
C
Iovane
Serena
S
Catalano
Amerigo
A
Giudice
Antonio
A
Crispino
Michele
M
Figliuzzi
Concetta
C
Irace
Leonzio
L
Fortunato
Agostino
A
Gnasso
D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D002339:Carotid Arteries / Q000503:physiopathology; D012534:Dental Scaling; D006439:Hemodynamics; D016745:Root Planing; D013314:Stress, Mechanical; D013997:Time Factors