Custom-Made Antibiotic Cement Nails in Orthopaedic Trauma: Review of Outcomes, New Approaches, and Perspectives.
Since the first description in 2002 by Paley and Herzenberg, antibiotic bone cement nails (ACNs) have become an effective tool in the orthopaedic trauma surgeons' hands. They simultaneously elute high amounts of antibiotics into medullary canal dead space and provide limited stability to the debrided long bone. In this paper, we perform a systematic review of current evidence on ACNs in orthopaedic trauma and provide an up-to-date review of the indications, operative technique, failure mechanisms, complications, outcomes, and outlooks for the ACNs use in long bone infection.
Department of Orthopaedics and Rheumoortopaedics, Prof. A. Gruca Teaching Hospital, Konarskiego 13, 05-400 Otwock, Poland.
Marcin K
MK
Wasko
Department of Trauma Surgery and Orthopaedics, Prof. A. Gruca Teaching Hospital, Konarskiego 13, 05-400 Otwock, Poland.
Rafal
R
Kaminski
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001843:Bone Cements; D001858:Bone Nails; D003646:Debridement / Q000379:methods; D016503:Drug Delivery Systems; D004867:Equipment Design; D006801:Humans; D008422:Materials Testing / Q000379:methods; D009983:Orthopedic Equipment; D009985:Orthopedics / Q000379:methods*; D010019:Osteomyelitis / Q000188:drug therapy; D014947:Wounds and Injuries / Q000601:surgery
D000900:Anti-Bacterial Agents; D001843:Bone Cements