Innervation of the cricothyroid muscle by extralaryngeal branches of the recurrent laryngeal nerve.
A major concern in thyroid surgery is possible changes in the patient's voice due to dysfunction of the laryngeal muscles. The classical understanding of the anatomy is that the cricothyroid muscle (CTM) is innervated solely by the external branch of the superior laryngeal nerve (EBSLN), and the endolaryngeal muscles are covered only by the recurrent laryngeal nerve (RLN). Meticulous anatomical studies found communication between these nerves. Recent neurophysiological studies revealed cross-innervations among these nerve-muscle sets. Here, we report innervation of the CTM by extralaryngeal branches of the RLN.



Clinical observation during thyroid surgery at a hospital center for thyroid diseases.



During thyroid cancer surgeries, we encountered four adult Japanese patients who had an extralaryngeal branch of the RLN, the electrical stimulation of which showed contraction of the CTM. The EBSLN and RLN were electrically stimulated. Responses were evaluated by visual observation of contraction of the CTM and palpable laryngeal twitch of the endolaryngeal muscles. Electromyographic studies were also performed in two patients.



Five of the seven RLNs examined showed contraction of the CTM on stimulation. Four of these five RLNs had an extralaryngeal branch that showed contraction of the CTM on stimulation. Stimulation of the RLN proximal to the branch yielded contraction of the CTM and laryngeal twitch, whereas stimulation of the RLN distal to the branch yielded only laryngeal twitch.



Extralaryngeal branches of the RLN innervated the CTM in four patients. This phenomenon might influence voice changes following thyroid surgery.



4. Laryngoscope, 126:1157-1162, 2016.
Department of Surgery, Kuma Hospital, Kobe, Japan.
Akira
A
Miyauchi
Department of Surgery, Kuma Hospital, Kobe, Japan.
Hiroo
H
Masuoka
Department of Head and Neck Surgery, Kuma Hospital, Kobe, Japan.
Ayako
A
Nakayama
Department of Surgery, Kuma Hospital, Kobe, Japan.
Takuya
T
Higashiyama
D000328:Adult; D004576:Electromyography; D005260:Female; D006801:Humans; D007821:Laryngeal Muscles / Q000294:innervation* / Q000502:physiology; D008297:Male; D008875:Middle Aged; D010699:Phonation; D012009:Recurrent Laryngeal Nerve / Q000033:anatomy & histology* / Q000502:physiology; D013965:Thyroidectomy / Q000009:adverse effects; D014832:Voice Disorders / Q000209:etiology
Recurrent laryngeal nerve; cricothyroid muscle; extralaryngeal branch; innervation; voice change