Successful Treatment of Propafenone Intoxication With Intravenous Lipid Emulsion.
Severe cardiac effects, including cardiac arrest, are a rare complication of high-dose propafenone intake. Among patients who experience cardiac arrest, the survival rate is low. This report presents the case of a young female patient who developed cardiac arrest linked to propafenone intake. While spontaneous circulation was restored with cardiopulmonary resuscitation, vital signs did not recover despite supportive treatment. However, after the administration of intravenous lipid emulsion (ILE), vital signs and cardiac functions resolved and the patient survived. This case is the second to describe the successful use of ILE for propafenone intoxication. However, as all of the findings of this patient were clearly linked to propafenone, we believe the benefits of ILE were more clearly defined in this case than in the other.
Department of Emergency Medicine, Dokuz Eylul University School of Medicine, Inciralti, Izmir, Turkey.
Başak
B
Bayram
Clinic of Anesthesiology and Reanimation, Izmir Tepecik Training and Research Hospital, Izmir, Turkey.
Işıl
I
Köse
Department of Emergency Medicine, Dokuz Eylul University School of Medicine, Inciralti, Izmir, Turkey.
Sinem
S
Avcı
Department of Cardiology, Dokuz Eylul University School of Medicine, Inciralti, Izmir, Turkey.
Abdulla
A
Arslan
Department of Emergency Medicine, Dokuz Eylul University School of Medicine, Inciralti, Izmir, Turkey.
Çağdaş
Ç
Acara
D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000633:toxicity*; D062787:Drug Overdose / Q000628:therapy*; D004562:Electrocardiography; D005217:Fat Emulsions, Intravenous; D005260:Female; D006323:Heart Arrest / Q000139:chemically induced* / Q000628:therapy*; D006801:Humans; D011405:Propafenone / Q000633:toxicity*; D013406:Suicide, Attempted
D000889:Anti-Arrhythmia Agents; D005217:Fat Emulsions, Intravenous; D011405:Propafenone
Propafenone; intoxication; lipid emulsion; lipid rescue