Variation in dielectric properties due to pathological changes in human liver.
Dielectric properties of freshly excised human liver tissues (in vitro) with several pathological conditions including cancer were obtained in frequency range 100 MHz-5 GHz. Differences in dielectric behavior of normal and pathological tissues at microwave frequencies are discussed based on histological information for each tissue. Data presented are useful for many medical applications, in particular nanosecond pulsed electroporation techniques. Knowledge of dielectric properties is vital for mathematical calculations of local electric field distribution inside electroporated tissues and can be used to optimize the process of electroporation for treatment planning procedures.
Department of Physical Dosimetry, Centre for Radiation, Chemicals and Environmental Hazards, Public Health England, Didcot, UK.
Azadeh
A
Peyman
Laboratory of Biocybernetics, Faculty of Electrical Engineering, University of Ljubljana, Ljubljana, Slovenia.
Bor
B
Kos
University Medical Centre Ljubljana, Ljubljana, Slovenia.
Mihajlo
M
Djokić
University Medical Centre Ljubljana, Ljubljana, Slovenia.
Blaž
B
Trotovšek
Institute of Pathology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.
Clara
C
Limbaeck-Stokin
Department of Experimental Oncology, Institute of Oncology, Ljubljana, Slovenia.
Gregor
G
Serša
Laboratory of Biocybernetics, Faculty of Electrical Engineering, University of Ljubljana, Ljubljana, Slovenia.
Damijan
D
Miklavčič
D000368:Aged; D017097:Electric Impedance; D005260:Female; D006801:Humans; D008099:Liver / Q000166:cytology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000473:pathology*
cancer; conductivity; electroporation; pathology; permittivity; tumor