Videofluoroscopic Predictors of Penetration-Aspiration in Parkinson's Disease Patients.
Parkinson's disease (PD) patients show a high prevalence of swallowing disorders and tracheal aspiration of food. The videofluoroscopic study of swallowing (VFSS) allows clinicians to visualize the visuoperceptual and temporal parameters associated with swallowing disorders in an attempt to predict aspiration risk. However, this subject remains understudied in PD populations. Our aim was to identify the predictors of penetration-aspiration in PD patients using the VFSS. Consecutive patients were evaluated using VFSS with different consistencies and volumes of food. A speech-language pathologist measured the type of intra-oral bolus organization, loss of bolus control, bolus location at the initiation of the pharyngeal swallow, the presence of multiple swallows, piecemeal deglutition, bolus residue in the pharyngeal recesses and temporal measures. Scores ≥3 on the penetration-aspiration scale (PAS) indicated the occurrence of penetration-aspiration. Using logistic marginal regression, we found that residue in the vallecula, residue in the upper esophageal sphincter and piecemeal deglutition were associated with penetration-aspiration (odds ratio (OR) = 4.09, 2.87 and 3.83; P = 0.0040, 0.0071 and 0.0009, respectively). Penetration/aspiration occurred only with fluids (both of thin and thick consistency), and no significant differences were observed between fluid types or food volumes. The mechanisms underlying dysphagia and penetration/aspiration in PD patients and indications for further studies are discussed.
Division of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil. nataliefono@gmail.com.
Natalie
N
Argolo
Division of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil.|Department of Speech-Language Pathology, Health Sciences Institute, Federal University of Bahia, Salvador, Bahia, Brazil.
Marília
M
Sampaio
Division of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil.
Patrícia
P
Pinho
Division of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil.
Ailton
A
Melo
Division of Neurology and Epidemiology, Federal University of Bahia, Rua Padre Feijó, 29 (4° floor) - Canela, Salvador, Bahia, 40.110-170, Brazil.|Department of Speech-Language Pathology, Health Sciences Institute, Federal University of Bahia, Salvador, Bahia, Brazil.
Ana Caline
AC
Nóbrega
D001938:Brazil / Q000453:epidemiology; D003680:Deglutition Disorders / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D005471:Fluoroscopy / Q000379:methods*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009305:Nasopharynx / Q000000981:diagnostic imaging* / Q000503:physiopathology; D010300:Parkinson Disease / Q000150:complications* / Q000175:diagnosis; D053120:Respiratory Aspiration / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D014741:Video Recording
Deglutition disorders; Parkinson’s disease; Penetration/aspiration