Use of Whole-Genome Sequencing to Link Burkholderia pseudomallei from Air Sampling to Mediastinal Melioidosis, Australia.
The frequency with which melioidosis results from inhalation rather than percutaneous inoculation or ingestion is unknown. We recovered Burkholderia pseudomallei from air samples at the residence of a patient with presumptive inhalational melioidosis and used whole-genome sequencing to link the environmental bacteria to B. pseudomallei recovered from the patient.
Bart J
BJ
Currie
Erin P
EP
Price
Mark
M
Mayo
Mirjam
M
Kaestli
Vanessa
V
Theobald
Ian
I
Harrington
Glenda
G
Harrington
Derek S
DS
Sarovich
D000391:Air Microbiology; D001315:Australia; D016957:Burkholderia pseudomallei / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D018562:Disease Transmission, Infectious; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000209:etiology* / Q000235:genetics / Q000382:microbiology / Q000635:transmission; D008875:Middle Aged; D017422:Sequence Analysis, DNA / Q000379:methods / Q000706:statistics & numerical data
Australia; Burkholderia pseudomallei; bacteria; biothreat; genome; gram-negative bacterial infections; melioidosis; pathogen transmission; pneumonia; zoonoses