Case Report: Brown Fat Accumulation of Tc-99m Macroaggregated Albumin in a Lung Perfusion Study in a Patient With Multiple Lung Arteriovenous Malformations and Right-to-Left Shunting.
An 18-year-old man was preoperatively assessed for a varicocele and found to be hypoxemic. A Tc-99m macroaggregated albumin lung perfusion scan showed right-to-left shunting, evidenced by increased radiotracer uptake in the brain, kidneys, thyroid gland, and bilateral supraclavicular areas, a typical location for brown adipose tissue. Chest computerized tomography angiogram study showed supraclavicular fat density areas and multiple pulmonary arteriovenous malformations.The authors report a rare case of brown fat visualization on a lung perfusion scan in a patient with right-to-left shunting, likely because of increased perfusion to activated brown adipose tissue.
From the Department of Radiology and Radiological Science, Division of Nuclear Medicine, Russell H. Morgan, Johns-Hopkins University School ofMedicine, Baltimore, MD (WM); Mallinckrodt Institute of Radiology, Washington University in St. Louis School Of Medicine, St. Louis, MO (RLW).
Wael
W
Marashdeh
Richard L
RL
Wahl
D002001:Adipose Tissue, Brown / Q000000981:diagnostic imaging* / Q000378:metabolism*; D000293:Adolescent; D001165:Arteriovenous Malformations / Q000150:complications / Q000000981:diagnostic imaging* / Q000378:metabolism*; D006330:Heart Defects, Congenital / Q000150:complications / Q000000981:diagnostic imaging* / Q000196:embryology*; D006801:Humans; D008168:Lung / Q000098:blood supply* / Q000000981:diagnostic imaging*; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D013668:Technetium Tc 99m Aggregated Albumin / Q000493:pharmacokinetics*; D014018:Tissue Distribution
D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin