Unique electrocatalytic activity of a nucleic acid-mimicking coordination polymer for the sensitive detection of coenzyme A and histone acetyltransferase activity.
A nucleic acid-mimicking CoA-Ag(I) coordination polymer (CP) was in situ prepared and its unique electrocatalytic activity to H2O2 reduction was discovered. Based on it, a novel, label-free electrochemical sensor has been developed for the sensitive detection of coenzyme A (CoA) and histone acetyltransferase (HAT) activity.
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. niezhou.hnu@gmail.com.
Yufang
Y
Hu
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. niezhou.hnu@gmail.com.
Siyu
S
Chen
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. niezhou.hnu@gmail.com.
Yitao
Y
Han
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. niezhou.hnu@gmail.com.
Hongjun
H
Chen
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. niezhou.hnu@gmail.com.
Qin
Q
Wang
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. niezhou.hnu@gmail.com.
Zhou
Z
Nie
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. niezhou.hnu@gmail.com.
Yan
Y
Huang
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. niezhou.hnu@gmail.com.
Shouzhuo
S
Yao
D002384:Catalysis; D003065:Coenzyme A / Q000032:analysis*; D004563:Electrochemistry; D051548:Histone Acetyltransferases / Q000378:metabolism*; D057230:Limit of Detection; D018625:Microscopy, Atomic Force; D009696:Nucleic Acids / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
D009696:Nucleic Acids; D011108:Polymers; D051548:Histone Acetyltransferases; D003065:Coenzyme A