Transcriptional control of tissue formation throughout root development.
Tissue patterns are dynamically maintained. Continuous formation of plant tissues during postembryonic growth requires asymmetric divisions and the specification of cell lineages. We show that the BIRDs and SCARECROW regulate lineage identity, positional signals, patterning, and formative divisions throughout Arabidopsis root growth. These transcription factors are postembryonic determinants of the ground tissue stem cells and their lineage. Upon further activation by the positional signal SHORT-ROOT (a mobile transcription factor), they direct asymmetric cell divisions and patterning of cell types. The BIRDs and SCARECROW with SHORT-ROOT organize tissue patterns at all formative steps during growth, ensuring developmental plasticity.
Department of Biotechnology, Center for Plant Genomics and Biotechnology, Universidad Politecnica de Madrid, 28223 Pozuelo de Alarcón (Madrid), Spain.
Miguel A
MA
Moreno-Risueno
Department of Biology and Howard Hughes Medical Institute, Duke University, Durham, NC 27708, USA.
Rosangela
R
Sozzani
Department of Biology and Howard Hughes Medical Institute, Duke University, Durham, NC 27708, USA.
Galip Gürkan
GG
Yardımcı
Department of Biology and Howard Hughes Medical Institute, Duke University, Durham, NC 27708, USA.
Jalean J
JJ
Petricka
Laboratoire de Reproduction et Développement des Plantes, CNRS, INRA, ENS Lyon, UCBL, Université de Lyon, 69364 Lyon, France.
Teva
T
Vernoux
Department of Plant Biology, Wageningen University Research, Wageningen, Netherlands.
Ikram
I
Blilou
Department of Plant and Microbial Biology, North Carolina State University, Raleigh, NC 27695, USA.
Jose
J
Alonso
Department of Biology and Howard Hughes Medical Institute, Duke University, Durham, NC 27708, USA.
Cara M
CM
Winter
Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany.
Uwe
U
Ohler
Department of Plant Biology, Wageningen University Research, Wageningen, Netherlands.
Ben
B
Scheres
Department of Biology and Howard Hughes Medical Institute, Duke University, Durham, NC 27708, USA. philip.benfey@duke.edu.
Philip N
PN
Benfey
D017360:Arabidopsis / Q000166:cytology / Q000235:genetics* / Q000254:growth & development*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D002455:Cell Division / Q000235:genetics; D019070:Cell Lineage / Q000235:genetics; D018506:Gene Expression Regulation, Plant; D018517:Plant Roots / Q000166:cytology / Q000235:genetics* / Q000254:growth & development*; D014157:Transcription Factors / Q000378:metabolism*; D014158:Transcription, Genetic
D029681:Arabidopsis Proteins; C100978:SCR protein, Arabidopsis; C410510:SHORT ROOT protein, Arabidopsis; D014157:Transcription Factors