Statin protects endothelial cell against ischemia reperfusion injury through HMGB1/TLR4 pathway.
Department of Cardiology, Second Xiangya Hospital of Central South University, Changsha, PR China.
Zhaowei
Z
Zhu
Department of Cardiology, Second Xiangya Hospital of Central South University, Changsha, PR China.
Zhenfei
Z
Fang
D004247:DNA / Q000235:genetics*; D005786:Gene Expression Regulation / Q000187:drug effects*; D024243:HMGB1 Protein / Q000235:genetics*; D006801:Humans; D015428:Myocardial Reperfusion Injury; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics*; D051057:Proto-Oncogene Proteins c-akt / Q000235:genetics*; D019821:Simvastatin / Q000008:administration & dosage*
D024243:HMGB1 Protein; D004247:DNA; D019821:Simvastatin; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt
Endothelial cell; HMGB1; Statin