Clinical perspectives on osteogenesis imperfecta versus non-accidental injury.
Although non-accidental injuries (NAI) are more common in cases of unexplained fractures than rare disorders such as osteogenesis imperfecta (OI), ruling out OI and other medical causes of fracture is always indicated. The majority of OI patients can be diagnosed with the help of family history, physical examination, and radiographic findings. In particular, there are a few radiological findings which are seen more commonly in NAI than in OI which may help guide clinician considerations regarding the probability of either of these diagnoses. At the same time, molecular testing still merits careful consideration in cases with unexplained fractures without obvious additional signs of abuse.
Elaine Maria
EM
Pereira
D002648:Child; D002649:Child Abuse / Q000175:diagnosis*; D003937:Diagnosis, Differential; D050723:Fractures, Bone / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D010013:Osteogenesis Imperfecta / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000235:genetics; D011859:Radiography; D014947:Wounds and Injuries / Q000000981:diagnostic imaging / Q000209:etiology*
child abuse; non-accidental injury; osteogenesis imperfecta; rib fractures