Delayed diagnosis leading to accelerated-phase chronic eosinophilic leukemia due to a cytogenetically cryptic, imatinib-responsive TNIP1-PDFGRB fusion gene.
Haematology Directorate, SA Pathology, Adelaide, South Australia, Australia.|Flinders University and Medical Centre, Adelaide, South Australia, Australia.|School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
D M
DM
Ross
Genetics and Molecular Pathology Directorate, SA Pathology, Adelaide, South Australia, Australia.
H K
HK
Altamura
School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.|Genetics and Molecular Pathology Directorate, SA Pathology, Adelaide, South Australia, Australia.|Centre for Cancer Biology, SA Pathology, Adelaide, South Australia, Australia.
C N
CN
Hahn
Genetics and Molecular Pathology Directorate, SA Pathology, Adelaide, South Australia, Australia.
M
M
Nicola
Genetics and Molecular Pathology Directorate, SA Pathology, Adelaide, South Australia, Australia.
A L
AL
Yeoman
Genetics and Molecular Pathology Directorate, SA Pathology, Adelaide, South Australia, Australia.
M R
MR
Holloway
Australian Cancer Research Foundation Genomics Facility, SA Pathology, Adelaide, South Australia, Australia.
J
J
Geoghegan
Centre for Cancer Biology, SA Pathology, Adelaide, South Australia, Australia.|Australian Cancer Research Foundation Genomics Facility, SA Pathology, Adelaide, South Australia, Australia.|School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
J
J
Feng
Centre for Cancer Biology, SA Pathology, Adelaide, South Australia, Australia.|Australian Cancer Research Foundation Genomics Facility, SA Pathology, Adelaide, South Australia, Australia.|School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.
A W
AW
Schreiber
Genetics and Molecular Pathology Directorate, SA Pathology, Adelaide, South Australia, Australia.|Centre for Cancer Biology, SA Pathology, Adelaide, South Australia, Australia.|School of Pharmacy and Medical Science, University of South Australia, Adelaide, South Australia, Australia.
S
S
Branford
Genetics and Molecular Pathology Directorate, SA Pathology, Adelaide, South Australia, Australia.
S
S
Moore
School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.|Genetics and Molecular Pathology Directorate, SA Pathology, Adelaide, South Australia, Australia.|Centre for Cancer Biology, SA Pathology, Adelaide, South Australia, Australia.|Australian Cancer Research Foundation Genomics Facility, SA Pathology, Adelaide, South Australia, Australia.|School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.|School of Pharmacy and Medical Science, University of South Australia, Adelaide, South Australia, Australia.
H S
HS
Scott
D000368:Aged; D000074322:Antineoplastic Agents, Immunological / Q000494:pharmacology*; D002908:Chronic Disease; D004268:DNA-Binding Proteins / Q000235:genetics*; D057210:Delayed Diagnosis; D050939:Gene Fusion; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000235:genetics; D000068877:Imatinib Mesylate / Q000494:pharmacology*; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D020641:Polymorphism, Single Nucleotide; D020574:Proto-Oncogene Proteins c-sis / Q000235:genetics*
D000074322:Antineoplastic Agents, Immunological; D004268:DNA-Binding Proteins; D020574:Proto-Oncogene Proteins c-sis; C117046:TNIP1 protein, human; D000068877:Imatinib Mesylate