Evaluation of the Lyra Direct Strep Assay To Detect Group A Streptococcus and Group C and G Beta-Hemolytic Streptococcus from Pharyngeal Specimens.
The Lyra Direct strep assay was compared to culture for its ability to detect Streptococcus group A and β-hemolytic groups C/G using rapid antigen-negative pharyngeal specimens (n = 161). The Lyra assay correctly detected all β-hemolytic streptococci (group A, n = 19; group C/G, n = 5). In batch mode, the Lyra assay reduced intralaboratory turnaround time by 60% (18.1 h versus 45.0 h) but increased hands-on time by 96% (3 min 16 s versus 1 min 40 s per specimen).
Department of Pathology & Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA Oakland University William Beaumont School of Medicine, Rochester, Michigan, USA bobby.boyanton@beaumont.edu.
Bobby L
BL
Boyanton
Department of Pathology & Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA.
Elizabeth M
EM
Darnell
Department of Pathology & Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA.
Anne E
AE
Prada
Department of Pathology & Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA.
Dana M
DM
Hansz
Department of Pathology & Laboratory Medicine, Beaumont Health, Royal Oak, Michigan, USA Oakland University William Beaumont School of Medicine, Rochester, Michigan, USA.
Barbara
B
Robinson-Dunn
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001431:Bacteriological Techniques / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000382:microbiology; D013291:Streptococcus / Q000145:classification* / Q000302:isolation & purification*; D013997:Time Factors; D055815:Young Adult