Predictors of Mortality in Patients Undergoing Mitral Valve Replacement.
OBJECTIVE
Although mitral valve replacement is frequently performed in patients of all age groups, there are few studies available which determine the causes of operative mortality in mitral valve replacement especially in our region. Therefore, the objective of this study was to identify factors that are significantly associated with operative mortality in mitral valve replacement.


METHODS
From August 2012 to March 2013, 80 consecutive patients undergoing mitral valve replacement in a single tertiary hospital were included. Patients with a history of previous coronary artery bypass graft surgery or congenital heart problems were excluded from the sample. The included patients were observed for a period of 30 days. Pre and post-operative variables were used to identify significant predictors of mortality.


RESULTS
The overall hospital mortality (30 days) was 15%. High post-perative creatinine (P =0.05), high ASO titre (P=0.03), young age (P=0.011), low cardiac output (P=0.0001), small mitral valve size (P=0.002) and new onset of atrial fibrillation (P=0.007) were the significant independent predictors of operative morality.


CONCLUSIONS
Mitral valve replacement can be performed in third world countries with limited resources with low mortality. However, optimal selection of mitral valve size can help to improve operative mortality.
Civil Hospital, Dow University of Health Sciences. dowite_mfk@hotmail.com.
Muhammad Farhan
MF
Khan
Muhammad Shahzeb
MS
Khan
Faizan Imran
FI
Bawany
Mudassir Iqbal
MI
Dar
Mehwish
M
Hussain
Saima
S
Farhan
Kaneez
K
Fatima
Khizar
K
Hamid
Mohammad Hussham
MH
Arshad
Maira
M
Aziz
Uswah
U
Siddiqi
Nashit Irfan
NI
Aziz
Muhammad Bazil
MB
Musharraf
Abdul Bari
AB
Khan
D000328:Adult; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000401:mortality* / Q000601:surgery*; D010154:Pakistan; D011183:Postoperative Complications / Q000401:mortality*; D011446:Prospective Studies; D012307:Risk Factors