Hierarchically micro-patterned nanofibrous scaffolds with a nanosized bio-glass surface for accelerating wound healing.
A composite scaffold with a controlled micro-pattern, nano-sized fiber matrix and surface-modified nanobioglass component was successfully prepared for skin wound healing by combining the patterning electrospinning with pulsed laser deposition strategies, and the hierarchical micro/nano structures and nano-sized bioglass in the scaffolds could synergistically improve the efficiency and re-epithelialization of wound healing.
College of Life and Environmental Sciences, Shanghai Normal University, No. 100 Guilin Road, Shanghai 200234, China. kqf@shnu.edu.cn.
He
H
Xu
Fang
F
Lv
Yali
Y
Zhang
Zhengfang
Z
Yi
Qinfei
Q
Ke
Chengtie
C
Wu
Mingyao
M
Liu
Jiang
J
Chang
D000818:Animals; D002516:Ceramics / Q000737:chemistry / Q000494:pharmacology; D061307:Human Umbilical Vein Endothelial Cells / Q000378:metabolism; D006801:Humans; D051379:Mice; D057139:Nanofibers / Q000737:chemistry / Q000648:ultrastructure; D054457:Tissue Scaffolds / Q000737:chemistry*; D014945:Wound Healing / Q000187:drug effects*
C022107:Bioglass