Loss of autoregulation in patients with intracerebral hemorrhage.
We evaluated cerebral vasomotor reactivity to acetazolamide in seven consecutive patients with intracerebral hemorrhage (ICH) with transcranial Doppler to evaluate autoregulation of cerebral blood flow in acute ICH. Two patients had prominent loss of vasoreactivity to acetazolamide stimulation. This suggests that autoregulation may be impaired in some patients with acute ICH. Further studies are required to determine the clinical implications of loss of autoregulation in acute phase of ICH.
A I
AI
Qureshi
J R
JR
Ottenlips
A R
AR
Colohan
M R
MR
Frankel