Analysis of factors in successful nasal endoscopic resection of nasopharyngeal angiofibroma.
CONCLUSIONS
Endoscopic resection of nasopharyngeal angiofibroma is less traumatic, causes less bleeding, and provides a good curative effect. Using pre-operative embolization and controlled hypotension, reasonable surgical strategies and techniques lead to successful resection tumors of a maximum Andrews-Fisch classification stage of III.


OBJECTIVE
To investigate surgical indications, methods, surgical technique, and curative effects of transnasal endoscopic resection of nasopharyngeal angiofibroma, this study evaluated factors that improve diagnosis and treatment, prevent large intra-operative blood loss and residual tumor, and increase the cure rate.


METHODS
A retrospective analysis was performed of the clinical data and treatment programs of 23 patients with nasopharyngeal angiofibroma who underwent endoscopic resection with pre-operative embolization and controlled hypotension. The surgical method applied was based on the size of tumor and extent of invasion. Curative effects were observed.


RESULTS
No intra-operative or perioperative complications were observed in 22 patients. Upon removal of nasal packing material 3-7 days post-operatively, one patient experienced heavy bleeding of the nasopharyngeal wound, which was treated compression hemostasis using post-nasal packing. Twenty-three patients were followed up for 6-60 months. Twenty-two patients experienced cure; one patient experienced recurrence 10 months post-operatively, and repeat nasal endoscopic surgery was performed and resulted in cure.
a Department of Otorhinolaryngology - Head and Neck Surgery , Lihuili Hospital of Ningbo University , Ningbo , PR China.
Dong
D
Ye
a Department of Otorhinolaryngology - Head and Neck Surgery , Lihuili Hospital of Ningbo University , Ningbo , PR China.
Zhisen
Z
Shen
a Department of Otorhinolaryngology - Head and Neck Surgery , Lihuili Hospital of Ningbo University , Ningbo , PR China.
Guoli
G
Wang
a Department of Otorhinolaryngology - Head and Neck Surgery , Lihuili Hospital of Ningbo University , Ningbo , PR China.
Hongxia
H
Deng
a Department of Otorhinolaryngology - Head and Neck Surgery , Lihuili Hospital of Ningbo University , Ningbo , PR China.
Shijie
S
Qiu
a Department of Otorhinolaryngology - Head and Neck Surgery , Lihuili Hospital of Ningbo University , Ningbo , PR China.
Yuna
Y
Zhang
D000293:Adolescent; D000328:Adult; D018322:Angiofibroma / Q000473:pathology / Q000601:surgery*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002648:Child; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D059747:Nasal Surgical Procedures / Q000379:methods*; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
Nasal endoscopy; prognosis; surgery; treatment