Maternal pre-pregnancy BMI and adverse pregnancy outcomes among Chinese women: Results from the C-ABCS.
The aim of this study was to investigate associations between pre-pregnancy body mass index (BMI) and adverse pregnancy outcomes among Chinese pregnant women. A prospective population-based cohort study was performed using data collected as part of the China-Anhui Birth Cohort Study or C-ABCS. A total of 13,121 pregnant women who received the ﬁrst prenatal visit were enrolled from November 2008 to October 2010. Logistic regression analysis was used to calculate associations between pre-pregnancy BMI and pregnancy outcomes. Results indicated that the increased pre-pregnancy BMI was associated with a number of adverse pregnancy outcomes such as hypertensive disorder (adjusted relative risk (ARR) 2.3, 95% confidence interval [CI] 1.5-3.6), gestational diabetes (ARR 3.5, 95% CI 2.3-5.2), caesarean delivery (ARR 2.0, 95% CI 1.6-2.4), and medically indicated preterm delivery (ARR 1.8, 95% CI 1.1-2.9). Women with pre-pregnancy BMI above the normal range pose an increased risk of adverse pregnancy outcomes.
a Department of Maternal , Child and Adolescent Health, School of Public Health, Anhui Medical University , Anhui , China.|b Anhui Provincial Key Laboratory of Population Health & Aristogenics , Anhui , China.
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Ding
a Department of Maternal , Child and Adolescent Health, School of Public Health, Anhui Medical University , Anhui , China.|b Anhui Provincial Key Laboratory of Population Health & Aristogenics , Anhui , China.
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Xu
a Department of Maternal , Child and Adolescent Health, School of Public Health, Anhui Medical University , Anhui , China.|b Anhui Provincial Key Laboratory of Population Health & Aristogenics , Anhui , China.
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Hao
a Department of Maternal , Child and Adolescent Health, School of Public Health, Anhui Medical University , Anhui , China.|b Anhui Provincial Key Laboratory of Population Health & Aristogenics , Anhui , China.
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Huang
a Department of Maternal , Child and Adolescent Health, School of Public Health, Anhui Medical University , Anhui , China.|b Anhui Provincial Key Laboratory of Population Health & Aristogenics , Anhui , China.
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Su
a Department of Maternal , Child and Adolescent Health, School of Public Health, Anhui Medical University , Anhui , China.|b Anhui Provincial Key Laboratory of Population Health & Aristogenics , Anhui , China.
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Tao
D000328:Adult; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D055815:Young Adult
Obesity; gestational diabetes; hypertensive disorder; overweight; preterm