Migraine with aura and TCD bubble-test: The significance of positive result.
OBJECTIVE
The association between the right-to-left shunt (RLS) and migraine with aura (MA) has been proven so far. The aim of this study was to determine if the presence of RLS detected as a result of transcranial doppler (TCD) bubble-test, makes any difference in clinical presentation, aura and headache in patients with MA.


METHODS
A single-group descriptive study was conducted on 153 patients diagnosed with MA. TCD bubble-test was performed on 135 of them. The recorded demographic and clinical features of patients were analyzed and compared with the results of the TCD bubble test.


RESULTS
In the group of 135 patients, 88 (65.2%) had positive TCD bubble-test. The difference in the investigated clinical features of patients of the patients and aura between the patients with and without RLS, was not found.


CONCLUSIONS
The results of our study confirm a high prevalence of right-to-left shunt in patients with MA, but the clinical relevance of this association was not shown.
Ana Lj
ALj
Podgorac
Jasna J
JJ
Zidverc-Trajković
Zagorka B
ZB
Jovanović
Aleksandra P
AP
Radojičić
Aleksandra M
AM
Pavlović
Milija D
MD
Mijajlović
Tamara
T
Svabić-Medjedović
Nadežda M
NM
Covičkovič-Šternič
D000328:Adult; D002560:Cerebrovascular Circulation / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020325:Migraine with Aura / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D011237:Predictive Value of Tests; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods*; D055815:Young Adult