Computational analysis of miRNA-target community network reveals cross talk among different metabolisms.
To date, only a few conserved miRNAs have been predicted in hexaploid (AABBDD) bread wheat and till now community behavior among miRNA is still in dark. Analysis of publically available 1287279 ESTs from NCBI resulted 262 putative pre-miRNAs and 39 novel mature miRNAs. A total 22,468 targets were identified on 21 chromosomes. MiRNA target community was identified for genomes with different levels of cross talks. Gene ontology of these community targets suggests their differential involvement in different metabolisms along with common and stringent involvement in nitrogen metabolism.
Centre for Agricultural Bio-Informatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi, India.
Deepti
D
Nigam
Centre for Agricultural Bio-Informatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi, India.
Puneet K
PK
Kadimi
Centre for Agricultural Bio-Informatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi, India.
Sanjeev
S
Kumar
Centre for Agricultural Bio-Informatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi, India.
Dwijesh Chandra
DC
Mishra
Centre for Agricultural Bio-Informatics, ICAR-Indian Agricultural Statistics Research Institute, Library Avenue, PUSA, New Delhi, India.
Anil
A
Rai
EST; FDR, false discovery rate; GRN, Gene Regulatory Network; MiRNA community; MicroRNAs; Nitrogen metabolism; miRNAs, microRNAs