Acute dapsone poisoning in a 3-year-old child: Case report with review of literature.
Dapsone (DDS-diamino diphenyl sulphone) is a sulfone antibiotic being used for a variety of clinical conditions. Poisoning in children by DDS is rarely reported. Poisoning in acute cases will be frequently unrecognized due to relative lack of severe signs and symptoms. Methemoglobinemia is the major life-threatening situation associated with poisoning of DDS. Hence, any delay for medical attention can lead to increased rate of mortality. In this case, we describe acute DDS poisoning in a 3-year-old child and the successful management using intravenous methylene blue.
Menon Narayanankutty Sunilkumar, Vadakut Krishnan Parvathy, Department of Paediatrics, Amala Institute of Medical Sciences, Amala Nagar, Thrissur 680555, Kerala, India.
Menon Narayanankutty
MN
Sunilkumar
Menon Narayanankutty Sunilkumar, Vadakut Krishnan Parvathy, Department of Paediatrics, Amala Institute of Medical Sciences, Amala Nagar, Thrissur 680555, Kerala, India.
Thekkuttuparambil Ananthanarayanan
TA
Ajith
Menon Narayanankutty Sunilkumar, Vadakut Krishnan Parvathy, Department of Paediatrics, Amala Institute of Medical Sciences, Amala Nagar, Thrissur 680555, Kerala, India.
Vadakut Krishnan
VK
Parvathy
Ascorbic acid; Dapsone; Hemolysis; Methemoglobinemia; Methylene blue