Adrenocortical tumor with precocious puberty in a 2-month-old girl.
Adrenocortical tumor is a rare childhood tumor with a median age at onset of 3.2 years. Virilization is the most common sign. Laparotomy is the reference treatment and has a favorable course. The diagnosis of adrenal tumor can be difficult. The main parameters of malignant tumors are size and metastasis. Analysis of TP53 mutation can facilitate final diagnosis. We report a case of virilizing adrenal tumor that developed in a 2-month-old girl, and which was treated with laparoscopic adrenalectomy.
Department of Pediatric Surgery, University of Caen Hospital, Caen, France.
Jean-Baptiste
JB
Marret
Department of Pediatric Surgery, University of Necker Hospital, Paris, France.
Lara
L
Raffoul
Department of Pediatric Endocrinology, University of Caen Hospital, Caen, France.|University of Caen Hospital, Caen, France.|University of Caen Normandy, UFR Medicine, Caen, France.
Virginie
V
Ribault
Department of Pediatric Surgery, University of Caen Hospital, Caen, France.|University of Caen Hospital, Caen, France.|University of Caen Normandy, UFR Medicine, Caen, France.
Philippe
P
Ravasse
Department of Pediatric Surgery, University of Caen Hospital, Caen, France.|University of Caen Hospital, Caen, France.|University of Caen Normandy, UFR Medicine, Caen, France.
Julien
J
Rod
D000306:Adrenal Cortex Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000315:Adrenalectomy / Q000379:methods*; D018268:Adrenocortical Carcinoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D010535:Laparoscopy / Q000379:methods*; D011629:Puberty, Precocious / Q000175:diagnosis / Q000209:etiology*; D014057:Tomography, X-Ray Computed
adrenocortical tumor; pediatric; virilization; young