Advances in Dental Materials through Nanotechnology: Facts, Perspectives and Toxicological Aspects.
Nanotechnology is currently driving the dental materials industry to substantial growth, thus reflecting on improvements in materials available for oral prevention and treatment. The present review discusses new developments in nanotechnology applied to dentistry, focusing on the use of nanomaterials for improving the quality of oral care, the perspectives of research in this arena, and discussions on safety concerns regarding the use of dental nanomaterials. Details are provided on the cutting-edge properties (morphological, antibacterial, mechanical, fluorescence, antitumoral, and remineralization and regeneration potential) of polymeric, metallic and inorganic nano-based materials, as well as their use as nanocluster fillers, in nanocomposites, mouthwashes, medicines, and biomimetic dental materials. Nanotoxicological aspects, clinical applications, and perspectives for these nanomaterials are also discussed.
Solid-Biological Interface Group (SolBIN), Departamento de Física, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
Gislaine C
GC
Padovani
Department of Restorative Dentistry, Faculdade de Farmácia, Odontologia e Enfermagem, Universidade Federal do Ceará, Fortaleza-CE, Brazil.
Victor P
VP
Feitosa
Department of Restorative Dentistry, Faculdade de Farmácia, Odontologia e Enfermagem, Universidade Federal do Ceará, Fortaleza-CE, Brazil; Dental Biomaterials and Minimally Invasive Dentistry, Departamento de Odontologia, Facultad de Ciencias de la Salud, Universidad CEU Cardenal Herrera, Valencia, Spain.
Salvatore
S
Sauro
Department of Endodontics, Georgia Regents University, College of Dental Medicine, Augusta, GA, USA.
Franklin R
FR
Tay
Faculdade de Odontologia, Pontifícia Universidade Católica de Campinas, Campinas-SP, Brazil.
Gabriela
G
Durán
Solid-Biological Interface Group (SolBIN), Departamento de Física, Universidade Federal do Ceará, Fortaleza-CE, Brazil. Electronic address: amaurijp@gmail.com.
Amauri J
AJ
Paula
Laboratory of Biological Chemistry, Intituto de Química, Universidade Estadual de Campinas (UNICAMP), Campinas-SP, Brazil; NanoBioss, Intituto de Química, UNICAMP, Campinas-SP, Brazil. Electronic address: duran@iqm.unicamp.br.
Nelson
N
Durán
D035843:Biomedical Research / Q000639:trends; D003764:Dental Materials / Q000009:adverse effects* / Q000627:therapeutic use*; D003813:Dentistry / Q000379:methods* / Q000639:trends; D049329:Nanostructures / Q000009:adverse effects* / Q000627:therapeutic use*; D036103:Nanotechnology / Q000379:methods*
D003764:Dental Materials
dental materials; dentistry; nanobiotechnology; nanotechnology