Bilateral Optic Pathway Ganglioglioma: The Fifth Case in the Literature.
Gangliogliomas are mixed tumors which contain both glial and neuronal elements. The optic pathway is a very rare location for gangliogliomas, with less than 23 cases reported in the literature. Bilateral involvement of the entire optic pathway was reported in only 4 cases before. Because of similar radiological appearance of other pathological entities such as gliomas and craniopharyngiomas, histopathological diagnosis is essential. We report a ganglioglioma case that involved both optic pathways. A 12-year-old patient suffering from visual deterioration for 6 months was evaluated. After a visual field test and radiological examinations, a microsurgical biopsy procedure was performed. Pathological examination revealed dysplastic/neoplastic ganglion cells and neoplastic glial cells, and the diagnosis was a World Health Organization (WHO) grade 1 ganglioglioma. The patient is scheduled for adjuvant radiotherapy with the hope of prevention of progression.
Division of Pediatric Neurosurgery, Gazi University Faculty of Medicine, Ankara, Turkey.
Burak
B
Karaaslan
Murat
M
Uçar
Gamze
G
Kulduk
Alp Özgün
AÖ
Börcek
M Kemali
MK
Baykaner
D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002648:Child; D003399:Craniotomy; D003937:Diagnosis, Differential; D005260:Female; D018303:Ganglioglioma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D014786:Vision Disorders / Q000209:etiology