Feasibility of a Text Messaging Intervention to Promote Self-Management for Patients Prescribed Oral Anticancer Agents.
OBJECTIVE
To determine proof of concept of a mobile health (mHealth) intervention delivering text messages (texts) to self-manage among patients prescribed oral anticancer agents (OAs) and to examine preliminary efficacy on symptoms and medication adherence.


METHODS
A longitudinal randomized, controlled trial.


METHODS
Two community cancer centers in the midwestern United States and a national specialty pharmacy.


METHODS
80 adults with cancer who were newly prescribed OAs .


METHODS
Adherence and symptoms were assessed weekly for 10 weeks in both groups. The intervention group received daily texts for adherence and weekly for symptoms for 21-28 days, and satisfaction with the intervention was assessed .


METHODS
Medication adherence and symptom severity.


RESULTS
Mean age was 58.5 years (SD = 10.7 years), 48 participants were female, and 48 were Caucasian. Fewer symptoms were found in the intervention group with a moderate effect size. Adherence was higher in the text group using medical record and prescription data (n = 26) with greater relative dose intensity of moderate to large effect size. Regarding acceptability, 57% (83 of 145) of eligible participants consented, 39 of 40 participants completed the entire intervention, 30 participants read texts all of the time, and 34 participants were satisfied with the intervention.


CONCLUSIONS
Proof of concept and preliminary efficacy of an mHealth intervention using texts to promote self-management for patients prescribed OAs was demonstrated. Patients had high satisfaction with the texts, and adherence and symptoms improved after the intervention.


CONCLUSIONS
Texts show promise for patients with cancer who must manage their OAs. Additional research is needed prior to use in practice.
Michigan State University in East Lansing.
Sandra L
SL
Spoelstra
Michigan State University.
Charles W
CW
Given
Michigan State University.
Alla
A
Sikorskii
Michigan State University.
Constantinos K
CK
Coursaris
Michigan State University.
Atreyee
A
Majumder
Michigan State University.
Tracy
T
DeKoekkoek
Michigan State University.
Monica
M
Schueller
College of Nursing, Michigan State University in East Lansing.
Barbara A
BA
Given
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*; D017060:Patient Satisfaction; D012648:Self Care; D011795:Surveys and Questionnaires; D060145:Text Messaging; D016903:Drug Monitoring
D000970:Antineoplastic Agents
PROMIS; SMS; cancer; mHealth; medication adherence; mobile phone; oral agent; text messaging