CREATION OF OINTMENT COMPOSITIONS CONTAINING PHENOL COMPOUNDS FOR MEDICAL TREATMENT.
The research was aimed at studying the possibility of obtaining drug ointments with a potential anti-mycotic activity by using thick extracts obtained from the leaves of fustic, hazel, nut and bark of the oak. There were prepared the ointment compositions on different bases. As a methodology for studying the properties of the obtained ointments, there have been used the studies of colloidal stability and resorption of tanning substances in agar. The obtained results allow for making conclusion that the selected ointments are colloidally stable, and the values of movement of zones of biologically active substances in the agar body are large enough. These data allow for forecasting both the possibility of creating the similar ointment systems and their rather high properties. Based on the obtained data, there have been selected the ointment composition variants for further studies.
Akaki Tsereteli State University, Kutaisi; I. Kutateladze Institute of Pharmacochemistry, Tbilisi, Georgia.
N
N
Abuladze
Akaki Tsereteli State University, Kutaisi; I. Kutateladze Institute of Pharmacochemistry, Tbilisi, Georgia.
M
M
Javakhia
Akaki Tsereteli State University, Kutaisi; I. Kutateladze Institute of Pharmacochemistry, Tbilisi, Georgia.
K
K
Gabunia
Akaki Tsereteli State University, Kutaisi; I. Kutateladze Institute of Pharmacochemistry, Tbilisi, Georgia.
P
P
Iavich
Akaki Tsereteli State University, Kutaisi; I. Kutateladze Institute of Pharmacochemistry, Tbilisi, Georgia.
M
M
Gabelashvili
D031162:Achillea / Q000737:chemistry; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D019306:Artemisia / Q000737:chemistry; D001234:Aspergillus niger / Q000187:drug effects / Q000254:growth & development; D031176:Bidens / Q000737:chemistry; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development; D041022:Candida tropicalis / Q000187:drug effects / Q000254:growth & development; D005079:Excipients / Q000737:chemistry / Q000494:pharmacology; D031315:Geranium / Q000737:chemistry; D036142:Mentha piperita / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D050178:Monoglycerides / Q000737:chemistry / Q000494:pharmacology; D009824:Ointments / Q000737:chemistry / Q000494:pharmacology*; D031316:Pelargonium / Q000737:chemistry; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry*; D010946:Plants, Medicinal; D027544:Salvia / Q000737:chemistry; D031362:Satureja / Q000737:chemistry; D014249:Trichophyton / Q000187:drug effects / Q000254:growth & development
D000935:Antifungal Agents; D005079:Excipients; D050178:Monoglycerides; D009824:Ointments; D010636:Phenols; D010936:Plant Extracts