Management of Indeterminate Cystic Kidney Lesions: Review of Contrast-enhanced Ultrasound as a Diagnostic Tool.
Indeterminate cystic kidney lesions found incidentally are an increasingly prevalent diagnostic challenge. Standard workup includes Bosniak classification with contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI). However, these tests are costly and not without risks. Contrast-enhanced ultrasound (CEUS) is a relatively new technique with lower risk of adverse events than iodine-containing contrast or gadolinium. In our review of the evidence for characterization of cystic kidney lesions with CEUS, CEUS displayed sensitivity (89%-100%) and negative predictive value (86%-100%) comparable to contrast-enhanced CT or MRI, with no decrease in specificity compared with CT and only a slight decrease compared with MRI.
Department of Medicine, Division of Nephrology and Hypertension, UNC Kidney Center, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address: emily_chang@med.unc.edu.
Emily H
EH
Chang
Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Wui K
WK
Chong
Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC and North Carolina State at Raleigh, Raleigh, NC.
Sandeep K
SK
Kasoji
Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC and North Carolina State at Raleigh, Raleigh, NC.
Paul A
PA
Dayton
Department of Medicine, Division of Hematology and Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.
W Kimryn
WK
Rathmell
D003287:Contrast Media; D003937:Diagnosis, Differential; D019468:Disease Management; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging*; D014463:Ultrasonography
D003287:Contrast Media