Hypoxia-recruited angiogenic neutrophils.
In this issue of Blood, Massena et al identify a novel CD49d+CXCR4highVEGFR1high population of neutrophils that specifically migrate to sites of hypoxia and enhance angiogenesis.
UNIVERSITY OF COLORADO.
Eric L
http://orcid.org/0000-0003-0744-6577
EL
Campbell
D000818:Animals; D005260:Female; D006801:Humans; D039441:Integrin alpha4 / Q000378:metabolism*; D007515:Islets of Langerhans / Q000378:metabolism*; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism*; D009504:Neutrophils / Q000378:metabolism*; D019718:Receptors, CXCR4 / Q000378:metabolism*; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism*; D040281:Vascular Endothelial Growth Factor Receptor-1 / Q000502:physiology*
D019718:Receptors, CXCR4; D042461:Vascular Endothelial Growth Factor A; D039441:Integrin alpha4; D040281:Vascular Endothelial Growth Factor Receptor-1