Platelet-Derived Growth Factor-Mediated Guided Bone Regeneration in Immediate Implant Placement in Molar Sites with Buccal Bone Defects.
This study compared the clinical outcomes of recombinant human platelet-derived growth factor BB and beta-tricalcium phosphate (rhPDGF-BB/βTCP) with guided bone regeneration (GBR) in immediate implant placement in molar extraction sockets with buccal bone defects versus conventional implant placement. Twenty-eight implants were placed in fourteen patients. Clinical and radiographic evaluations assessed peri-implant soft and hard tissue parameters after 12 months. No implants were lost during the 1-year observation period, yielding a survival rate of 100%. Similar clinical and radiographic parameters were observed for both treatment groups. Use of rhPDGF-BB/βTCP and GBR in immediate implants in molars was as successful as conventional implant placement in fully healed extraction sites.
Ronaldo B
RB
Santana
Carolina Mm
CM
Santana
Serge
S
Dibart
D000328:Adult; D001861:Bone Regeneration / Q000187:drug effects*; D002130:Calcium Phosphates / Q000008:administration & dosage; D003758:Dental Implantation, Endosseous / Q000379:methods*; D048091:Guided Tissue Regeneration / Q000379:methods*; D006801:Humans; D008963:Molar; D010982:Platelet-Derived Growth Factor / Q000008:administration & dosage*; D011446:Prospective Studies; D011861:Radiography, Dental; D011994:Recombinant Proteins / Q000008:administration & dosage; D014081:Tooth Extraction; D016896:Treatment Outcome
D002130:Calcium Phosphates; D010982:Platelet-Derived Growth Factor; D011994:Recombinant Proteins; C485817:beta-tricalcium phosphate