[ANTIPLATELET THERAPY INFLUENCE ON IMMUNOLOGICAL STATUS OF PROGRESSIVE ANGINA PATIENTS].
The study involved 65 progressive angina patients (PA) aged 67 to 73 years. Determination of lymphocytes population and subpopulation was performed by monoclonal antibodies. Immunoglobulin G, A, M and circulating immune complexes (CIC) determination in the blood serum was performed by the Mancini method. The results showed that the clopidogrel with aspirin (aspihrel) combination in the basic treatment of PA patients is more effective than the basic treatment that included only clopidogrel, as evidenced by the positive trend of more indicators of immune status of patients.
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D000368:Aged; D000787:Angina Pectoris / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use*; D000077144:Clopidogrel; D018450:Disease Progression; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D056724:Immunity, Humoral / Q000187:drug effects*; D007136:Immunoglobulins / Q000097:blood; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016896:Treatment Outcome
D007136:Immunoglobulins; D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin