Analysis of chemical properties of edible and medicinal ginger by metabolomics approach.
In traditional herbal medicine, comprehensive understanding of bioactive constituent is important in order to analyze its true medicinal function. We investigated the chemical properties of medicinal and edible ginger cultivars using a liquid-chromatography mass spectrometry (LC-MS) approach. Our PCA results indicate the importance of acetylated derivatives of gingerol, not gingerol or shogaol, as the medicinal indicator. A newly developed ginger cultivar, Z. officinale cv. Ogawa Umare or "Ogawa Umare" (OG), contains more active ingredients, showing properties as a new resource for the production of herbal medicines derived from ginger in terms of its chemical constituents and rhizome yield.
College of Pharmaceutical Science, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga 525-8577, Japan.
Ken
K
Tanaka
Center for Information Biology, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan ; RIKEN Center for Sustainable Resource Science, Yokohama, Tsurumi 230-0045, Japan.
Masanori
M
Arita
Department of Cancer Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan.
Hiroaki
H
Sakurai
Graduate School of Information Science, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan.
Naoaki
N
Ono
Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan.
Yasuhiro
Y
Tezuka
D000284:Administration, Oral; D002853:Chromatography, Liquid / Q000379:methods; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000378:metabolism; D005504:Food Analysis / Q000379:methods*; D020939:Zingiber officinale / Q000737:chemistry* / Q000378:metabolism; D055442:Metabolome; D055432:Metabolomics / Q000379:methods*; D010936:Plant Extracts / Q000008:administration & dosage; D017365:Spices / Q000032:analysis*
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts