Novel Analytical Workflow for Comprehensive Non-targeted Phytochemical Metabolic Profiling.
The understanding and interpretation of pharmacological properties on a molecular level is of great importance for many different fields of research. Our study provides a novel model work-flow for comprehensive metabolic profiling by structural identification of relevant metabolites not limited to phytochemistry applications. High resolution liquid chromatography mass spectrometry LC-MS/MS data can be directly correlated with pharmacological test results on a molecular level. Thus the understanding and interpretation of pharmacological properties is supported by structural and chemical information.
University of Applied Sciences, Northwestern Switzerland, School of Life Sciences, Institute for Chemistry and Bioanalytics, Gründenstrasse 40, CH-4132 Muttenz, Switzerland.
Timm
T
Hettich
University of Applied Sciences, Northwestern Switzerland, School of Life Sciences, Institute for Chemistry and Bioanalytics, Gründenstrasse 40, CH-4132 Muttenz, Switzerland. goetz.schlotterbeck@fhnw.ch.
Götz
G
Schlotterbeck
D000367:Age Factors; D031723:Bambusa / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D062126:Databases, Chemical; D016208:Databases, Factual; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D055442:Metabolome; D055432:Metabolomics / Q000295:instrumentation / Q000379:methods*; D018515:Plant Leaves / Q000737:chemistry*; D053719:Tandem Mass Spectrometry; D057188:Workflow