Patient reported outcomes following stereotactic ablative radiotherapy or surgery for stage IA non-small-cell lung cancer: Results from the ROSEL multicenter randomized trial.
We report quality of life and indirect costs from patient reported outcomes from the ROSEL randomized control trial comparing stereotactic ablative radiotherapy (SABR, also known as stereotactic body radiotherapy or SBRT) versus surgical resection for medically operable stage IA non-small cell lung cancer. ROSEL closed prematurely after accruing and randomizing 22 patients. This exploratory analysis found the global health related quality of life and indirect costs to be significantly favorable and cheaper, with SABR.
Department of Radiation Oncology, VU University Medical Center, Amsterdam, Netherlands; Department of Radiation Oncology, London Regional Cancer Program, Canada. Electronic address: dr.alexlouie@gmail.com.
Alexander V
AV
Louie
Department of Biometrics, Netherlands Cancer Institute, Amsterdam, Netherlands.
Erik
E
van Werkhoven
Department of Radiation Oncology, London Regional Cancer Program, Canada.
Hanbo
H
Chen
Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, Netherlands.
Egbert F
EF
Smit
Department of Cardiothoracic Surgery, VU University Medical Center, Amsterdam, Netherlands.
Marinus A
MA
Paul
Department of Radiation Oncology, University Medical Center Groningen, Netherlands.
Joachim
J
Widder
Department of Pulmonary Diseases, University Medical Center Groningen, Netherlands.
Harry J M
HJ
Groen
Department of Pulmonary Diseases, Catharina Hospital, Eindhoven, Netherlands.
Ben E E M
BE
van den Borne
Department of Radiation Oncology, Catharina Hospital, Eindhoven, Netherlands.
Katrien
K
De Jaeger
Department of Radiation Oncology, VU University Medical Center, Amsterdam, Netherlands.
Ben J
BJ
Slotman
Department of Radiation Oncology, VU University Medical Center, Amsterdam, Netherlands.
Suresh
S
Senan
D002289:Carcinoma, Non-Small-Cell Lung / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D013510:Pulmonary Surgical Procedures; D011788:Quality of Life; D016634:Radiosurgery; D057566:Self Report; D016896:Treatment Outcome
Lung cancer; Patient reported outcomes; Quality of life; SABR; SBRT; Surgery