Oral cavity squamous cell carcinoma metastatic to central compartment (level 6) lymph nodes.
Alterations to drainage pathways in the head and neck as a result of surgical manipulation are not well understood. We present two unusual cases of oral squamous cell carcinoma metastatic to the level 6 nodal compartment following extensive treatment. Both oral squamous cell carcinoma cases exhibited metastases to the central neck compartment following extensive surgery and radiation. Each patient had prior history of multifocal oral cavity disease and recurrent neck metastases requiring salvage lymphadenectomy. Surgical interventions may alter the usual lymphatic drainage patterns. In cases of extensive treatment, all levels of the neck should be monitored for lymph node recurrence. Laryngoscope, 126:1803-1805, 2016.
Department of Otolaryngology, Mount Sinai Beth Israel, New York, New York.
Ilya
I
Likhterov
Department of Otolaryngology, Mount Sinai Beth Israel, New York, New York.|Thyroid, Head and Neck Cancer (THANC) Foundation, New York, New York.
Meghan E
ME
Rowe
Department of Radiology, Mount Sinai Beth Israel, New York, New York, U.S.A.
Azita S
AS
Khorsandi
Department of Otolaryngology, Mount Sinai Beth Israel, New York, New York.|Thyroid, Head and Neck Cancer (THANC) Foundation, New York, New York.|Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, New York.
Mark L
ML
Urken
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D009062:Mouth Neoplasms / Q000473:pathology*; D009333:Neck
Oral cavity; central neck metastasis; lymphatic drainage; radiation therapy; reconstructive surgery