[Explorations of epileptic network with cortico-cortical evoked potential].
OBJECTIVE
To evaluate the cortico-cortical evoked potential (CCEP) in exploring the network in epileptics.


METHODS
Two patients with intractable epilepsy underwent chronic intracranial electrode placement. According to the distribution of icta onset zones and the functional brain mapping, alternating 1 Hz electrical stimuli were delivered to the target electrodes. And CCEPs were recorded by averaging electrocorticograms time-locked to stimuli from subdural electrodes. Then icta onset zones, eloquent areas identified by electrical cortical mapping and CCEP distributions were compared.


RESULTS
Typical CCEP responses were observed. The data of one patient was useful for investigating the connectivity associated with various brain networks while another patient was useful for evaluating the cortical excitability.


CONCLUSIONS
The exploration of epileptic network is achieved through cortico-cortical evoked potential by investigating the connectivity associated with various brain networks and cortical excitability.
Huang
H
Chaoyang
Zhang
Z
Guojun
Wang
W
Yuping
Ni
N
Duanyu
Yu
Y
Tao
Chen
C
Nan
Du
D
Wei
Ren
R
Zhiwei
D001921:Brain; D001931:Brain Mapping; D004558:Electric Stimulation; D004566:Electrodes; D004827:Epilepsy; D005071:Evoked Potentials; D006801:Humans