Robotic, laparoscopic and open surgery for gastric cancer compared on surgical, clinical and oncological outcomes: a multi-institutional chart review. A study protocol of the International study group on Minimally Invasive surgery for GASTRIc Cancer-IMIGASTRIC.
BACKGROUND
Gastric cancer represents a great challenge for healthcare providers and requires a multidisciplinary treatment approach in which surgery plays a major role. Minimally invasive surgery has been progressively developed, first with the advent of laparoscopy and recently with the spread of robotic surgery, but a number of issues are currently being debated, including the limitations in performing an effective extended lymph node dissection, the real advantages of robotic systems, the role of laparoscopy for Advanced Gastric Cancer, the reproducibility of a total intracorporeal technique and the oncological results achievable during long-term follow-up.


METHODS
A multi-institutional international database will be established to evaluate the role of robotic, laparoscopic and open approaches in gastric cancer, comprising of information regarding surgical, clinical and oncological features. A chart review will be conducted to enter data of participants with gastric cancer, previously treated at the participating institutions. The database is the first of its kind, through an international electronic submission system and a HIPPA protected real time data repository from high volume gastric cancer centres.


BACKGROUND
This study is conducted in compliance with ethical principles originating from the Helsinki Declaration, within the guidelines of Good Clinical Practice and relevant laws/regulations. A multicentre study with a large number of patients will permit further investigation of the safety and efficacy as well as the long-term outcomes of robotic, laparoscopic and open approaches for the management of gastric cancer.


BACKGROUND
NCT02325453; Pre-results.
Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy.
Jacopo
J
Desiderio
Department of General Surgery, Jinling Hospital, Medical School, Nanjing University, Nanjing, China.
Zhi-Wei
ZW
Jiang
Department of Surgery, Division of Gastrointestinal Surgery, University of California, Irvine Medical Center, Orange, California, USA.
Ninh T
NT
Nguyen
Department of General Surgery, Jinling Hospital, Medical School, Nanjing University, Nanjing, China.
Shu
S
Zhang
Chirurgische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universität München, München, Germany.
Daniel
D
Reim
Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
Orhan
O
Alimoglu
Unité des Maladies de l'Appareil Digestif et Endocrine (UMADE), Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg.
Juan-Santiago
JS
Azagra
Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China.
Pei-Wu
PW
Yu
Division of General Surgery, Sunnybrook Health Sciences Centre, Toronto, Canada.
Natalie G
NG
Coburn
Department of Gastrointestinal Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Feng
F
Qi
Division of General Surgery, Medstar Georgetown University Hospital, Washington DC, USA.
Patrick G
PG
Jackson
Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Lu
L
Zang
Department of Surgical Oncology and HPB Surgery, Englewood Hospital and Medical Center, Englewood, New Jersey, USA.
Steven T
ST
Brower
Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Yukinori
Y
Kurokawa
Service de chirurgie digestive et cancérologique CHU Bocage. Dijon, France.
Olivier
O
Facy
Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Hironori
H
Tsujimoto
Division of Oncological and Robotic Surgery, Department of Oncology, Careggi University Hospital, Florence, Italy.
Andrea
A
Coratti
Division of Oncological and Robotic Surgery, Department of Oncology, Careggi University Hospital, Florence, Italy.
Mario
M
Annecchiarico
Department of General Surgery, Division of General, Gastroenterologic and Minimally Invasive Surgery, GB Morgagni Hospital, Forlì, Italy.
Francesca
F
Bazzocchi
Department of General Surgery, Division of General, Gastroenterologic and Minimally Invasive Surgery, GB Morgagni Hospital, Forlì, Italy.
Andrea
A
Avanzolini
Digestive and Hepatobiliary Surgery Department, University of Auvergne, University Hospital Estaing, Clermont-Ferrand, France.
Johan
J
Gagniere
Digestive and Hepatobiliary Surgery Department, University of Auvergne, University Hospital Estaing, Clermont-Ferrand, France.
Denis
D
Pezet
Department of Surgery and Translational Medicine, Center of Oncological Minimally Invasive Surgery (COMIS), University of Florence, Florence, Italy.
Fabio
F
Cianchi
Department of Surgery and Translational Medicine, Center of Oncological Minimally Invasive Surgery (COMIS), University of Florence, Florence, Italy.
Benedetta
B
Badii
Chirurgische Klinik und Poliklinik, Klinikum Rechts der Isar der Technischen Universität München, München, Germany.
Alexander
A
Novotny
Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
Tunc
http://orcid.org/0000-0001-7651-4321
T
Eren
Department of General Surgery, School of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
Metin
M
Leblebici
Unité des Maladies de l'Appareil Digestif et Endocrine (UMADE), Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg.
Martine
M
Goergen
Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China.
Ben
B
Zhang
Department of General Surgery, Third Military Medical University Southwest Hospital, Chongqing, China.
Yong-Liang
YL
Zhao
Department of Gastrointestinal Surgery, Tianjin Medical University General Hospital, Tianjin, China.
Tong
T
Liu
Division of General Surgery, Medstar Georgetown University Hospital, Washington DC, USA.
Waddah
W
Al-Refaie
Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China.
Junjun
J
Ma
Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
Shuji
S
Takiguchi
Service de chirurgie digestive et cancérologique CHU Bocage. Dijon, France.
Jean-Baptiste
JB
Lequeu
Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy.
Stefano
S
Trastulli
Department of Digestive Surgery, St Mary's Hospital, University of Perugia, Terni, Italy.
Amilcare
A
Parisi
D016208:Databases, Factual; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D015203:Reproducibility of Results; D012107:Research Design; D012189:Retrospective Studies; D012371:Robotics / Q000295:instrumentation*; D013274:Stomach Neoplasms / Q000601:surgery*; D016896:Treatment Outcome
SURGERY