The Relationship between Corvis ST Tonometry Measured Corneal Parameters and Intraocular Pressure, Corneal Thickness and Corneal Curvature.
The purpose of the study was to investigate the correlation between Corneal Visualization Scheimpflug Technology (Corvis ST tonometry: CST) parameters and various other ocular parameters, including intraocular pressure (IOP) with Goldmann applanation tonometry. IOP with Goldmann applanation tonometry (IOP-G), central corneal thickness (CCT), axial length (AL), corneal curvature, and CST parameters were measured in 94 eyes of 94 normal subjects. The relationship between ten CST parameters against age, gender, IOP-G, AL, CST-determined CCT and average corneal curvature was investigated using linear modeling. In addition, the relationship between IOP-G versus CST-determined CCT, AL, and other CST parameters was also investigated using linear modeling. Linear modeling showed that the CST measurement 'A time-1' is dependent on IOP-G, age, AL, and average corneal curvature; 'A length-1' depends on age and average corneal curvature; 'A velocity-1' depends on IOP-G and AL; 'A time-2' depends on IOP-G, age, and AL; 'A length-2' depends on CCT; 'A velocity-2' depends on IOP-G, age, AL, CCT, and average corneal curvature; 'peak distance' depends on gender; 'maximum deformation amplitude' depends on IOP-G, age, and AL. In the optimal model for IOP-G, A time-1, A velocity-1, and highest concavity curvature, but not CCT, were selected as the most important explanatory variables. In conclusion, many CST parameters were not significantly related to CCT, but IOP usually was a significant predictor, suggesting that an adjustment should be made to improve their usefulness for clinical investigations. It was also suggested CST parameters were more influential for IOP-G than CCT and average corneal curvature.
Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Ryo
R
Asaoka
Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan.
Shunsuke
S
Nakakura
Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan.
Hitoshi
H
Tabuchi
Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Hiroshi
H
Murata
Department of Ophthalmology and Visual Science, Hiroshima University, Hiroshima Japan.
Yoshitaka
Y
Nakao
Department of Ophthalmology and Visual Science, Hiroshima University, Hiroshima Japan.
Noriko
N
Ihara
Department of Ophthalmology and Visual Science, Hiroshima University, Hiroshima Japan; Faculty of Health Science, UIN Alauddin Makassar, Sulawesi Selatan, Indonesia.
Ulfah
U
Rimayanti
Department of Ophthalmology, The University of Tokyo, Tokyo, Japan.
Makoto
M
Aihara
Department of Ophthalmology and Visual Science, Hiroshima University, Hiroshima Japan.
Yoshiaki
Y
Kiuchi
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000502:physiology*; D004548:Elasticity; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011446:Prospective Studies; D014065:Tonometry, Ocular / Q000379:methods*; D055815:Young Adult