Risk of decline and chance of improvement in olfaction among patients with post-traumatic olfactory loss.
OBJECTIVE
To evaluate the chance of improvement and risk of decline in olfaction among patients with post-traumatic olfactory loss.


METHODS
This study comprised 80 patients. Changes in olfaction were determined using a visual analogue scale and the 'Sniffin' Sticks' test. Logistic regression was used to identify predictors for olfactory changes.


RESULTS
Olfactory changes were observed in 9-35 per cent of patients. The rates of improvement and decline according to visual analogue scale scores were 35 per cent and 10 per cent respectively, whereas those in the Sniffin' Sticks test were 9 per cent and 11 per cent respectively. There was a predictive link between non-anosmia and decline in Sniffin' Sticks test scores (odds ratio = 16.61, p = 0.003). A positive correlation was observed between the scores in the first and last examinations (rho = 0.532, p < 0.001).


CONCLUSIONS
Patients should be informed that they may experience an improvement or decline in olfaction following post-traumatic olfactory dysfunction. This study provides evidence to support comprehensive counselling regarding prognosis as an integral part of management strategies.
Department of Otolaryngology - Head and Neck Surgery,Taipei Veterans General Hospital,Taipei,Taiwan,Republic of China.
C-L
CL
Kuo
Department of Otolaryngology - Head and Neck Surgery,Taipei Veterans General Hospital,Taipei,Taiwan,Republic of China.
C-H
CH
Shu
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D015331:Cohort Studies; D006259:Craniocerebral Trauma / Q000150:complications* / Q000175:diagnosis; D018450:Disease Progression; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D000857:Olfaction Disorders / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology*; D011379:Prognosis; D011788:Quality of Life; D012075:Remission, Spontaneous; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors; D055815:Young Adult
Head Injuries; Olfaction Disorders; Post-Traumatic; Smell