Gene expression analysis of laryngeal squamous cell carcinoma.
Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignancies of the head and neck tumors Zhang et al., 2013 [1]). Previous studies have associated its occurrence with social activities, such as tobacco and alcohol consumption (Hashibe et al., 2007a [2]; Hashibe et al., 2007b [3]; Shangina et al., 2006 [4]). Here, we performed a genome-wide gene expression profiling in thirty-one patients positively diagnosed for LSCC, in order to investigate new targets involved in tumorigenesis.
National Institute of Science and Technology in Stem Cell and Cell Therapy and Center For Cell-Based Therapy, Rua Tenente Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil ; Center for Integrative Systems Biology, CISBi, NAP/USP, Rua Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil.
Jessica Rodrigues
JR
Plaça
Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, SP CEP 14049-900, Brazil ; National Institute of Science and Technology in Stem Cell and Cell Therapy and Center For Cell-Based Therapy, Rua Tenente Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil.
Rafaela de Barros E Lima
Rde B
Bueno
Department of Technology, College of Agriculture and Veterinary Sciences, UNESP, Via de acesso Prof. Paulo Donato Castellane, s/n, Jaboticabal, SP CEP 14884-900, Brazil.
Daniel Guariz
DG
Pinheiro
National Institute of Science and Technology in Stem Cell and Cell Therapy and Center For Cell-Based Therapy, Rua Tenente Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil.
Rodrigo Alexandre
RA
Panepucci
Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, SP CEP 14049-900, Brazil ; National Institute of Science and Technology in Stem Cell and Cell Therapy and Center For Cell-Based Therapy, Rua Tenente Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil.
Luiza Ferreira
LF
de Araújo
Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Ribeirão Preto Medical School, University of São Paulo, Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, SP CEP 14049-900, Brazil.
Rui Celso Martins
RC
Mamede
University of Centro-Oeste, Rua Padre Salvador, 875, Santa Cruz, Guarapuava, PR CEP 85015-430, Brazil.
David Livingstone Alves
DL
Figueiredo
Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Avenida Bandeirantes 3900, Monte Alegre, Ribeirão Preto, SP CEP 14049-900, Brazil ; National Institute of Science and Technology in Stem Cell and Cell Therapy and Center For Cell-Based Therapy, Rua Tenente Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil ; Center for Integrative Systems Biology, CISBi, NAP/USP, Rua Catão Roxo, 2501, Monte Alegre, Ribeirão Preto, SP CEP 14051-140, Brazil.
Wilson Araújo
WA
Silva
Gene expression profile; Laryngeal squamous cell carcinoma tumor; Microarray