title: Patterns of Change During the Dermoscopic Follow-Up of Melanocytic Lesions in High Risk Patients.
abstract: BACKGROUND
  Melanomas and melanocytic nevi that change over time display different change patterns, correlated with histopathological features.
  
  
  METHODS
  We performed a retrospective analysis of the dermoscopic images corresponding to 86 lesions excised due to the changes occurred during the follow-up period in patients at high risk for melanoma, and we drew a comparison between the changes occurring in melanomas and those occurring in melanocytic nevi.
  
  
  RESULTS
  There were significant differences between the models of dermoscopic change characteristic to melanoma and those characteristic to melanocytic nevi. We observed changes with high specificity for the diagnosis of melanoma - asymmetric growth (Sp=90%), new structureless grey-blue areas (Sp=97.5%) or new grey-blue network (Sp=96.25%), new pseudopods or radial streaks (Sp=95%).
  
  
  CONCLUSIONS
  Our study highlights highly specific changes whose presence should raise the suspicion of melanoma and lead to the excision of the lesion.
authors.affiliation: Department of Dermatology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Loredana
authors.initials: L
authors.lastname: Ungureanu
authors.affiliation: Department of Dermatology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Alina
authors.initials: A
authors.lastname: Letcă
authors.affiliation: Department of Dermatology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Simona Corina
authors.initials: SC
authors.lastname: Șenilă
authors.affiliation: Department of Dermatology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Ana Sorina
authors.initials: AS
authors.lastname: Dănescu
authors.affiliation: Department of Dermatology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Rodica
authors.initials: R
authors.lastname: Cosgarea
keywords: dermoscopy; melanocytic nevi; melanoma