title: Parameters of Microcirculation in the Broad Ligament of the Uterus in Wistar Rats after Injection of Autologous Biomedical Cell Product.
abstract: We studied the effects of autologous biomedical cell product (bone marrow multipotent mesenchymal stromal cells and their conditioned media) on the parameters of the microcirculatory bed in the broad ligament of the uterus of normal Wistar rats were studied. The parameters of microcirculation and lymph drainage in the broad ligament changed in opposite directions in response to injection of autologous biomedical cell product via different routes. This fact should be taken into consideration when prescribing cell therapy for inflammatory degenerative processes in the pelvic organs.
authors.affiliation: Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia. dr-tanja@yandex.ru.
authors.forename: T I
authors.initials: TI
authors.lastname: Dergacheva
authors.affiliation: Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: A P
authors.initials: AP
authors.lastname: Lykov
authors.affiliation: Institute of Physiology and Basic Medicine, Novosibirsk, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Shurlygina
authors.affiliation: Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Starkova
authors.affiliation: Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Poveshchenko
authors.affiliation: Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Bondarenko
authors.affiliation: Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: I I
authors.initials: II
authors.lastname: Kim
authors.affiliation: Institute of Physiology and Basic Medicine, Novosibirsk, Russia.
authors.forename: M V
authors.initials: MV
authors.lastname: Tenditnik
authors.affiliation: Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: Yu I
authors.initials: YI
authors.lastname: Borodin
authors.affiliation: Institute of Clinical and Experimental Lymphology, Novosibirsk, Russia.
authors.forename: V I
authors.initials: VI
authors.lastname: Konenkov
mesh_terms: D000818:Animals; D001956:Broad Ligament / Q000098:blood supply* / Q000187:drug effects; D002478:Cells, Cultured; D017077:Culture Media, Conditioned / Q000737:chemistry / Q000494:pharmacology; D005260:Female; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D008833:Microcirculation / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D014182:Transplantation, Autologous; D014599:Uterus / Q000098:blood supply* / Q000187:drug effects
chemical_list: D017077:Culture Media, Conditioned
keywords: autologous biomedical cell product; broad ligament of the uterus; conditioned medium; microcirculation; multipotent mesenchymal stromal cells