title: NOVEL INSIGHTS ON INTAKE OF MEAT AND PREVENTION OF SARCOPENIA: ALL REASONS FOR AN ADEQUATE CONSUMPTION.
abstract: BACKGROUND
  sarcopenia is defined as a syndrome characterized by progressive and generalized loss of muscle mass and strength. The main cause of sarcopenia is the alteration of protein metabolism, in which the proteolytic processes are not accompanied by an appropriate protein synthesis and muscle cells lose progressively the sensitivity to the anabolic stimulus. The most rational approach to delay the progression of sarcopenia and counteract the anabolic resistance is proper nutrition. Meat contains biologically active compounds, such as creatine, carnitine, Conjugated Linoleic Acid (CLA) which have significant impacts upon human protein metabolism.
  
  
  METHODS
  we performed a narrative literature review to evaluate the till-now evidence regarding: 1. adequate intake of meat in elderly as a topic for prevention of sarcopenia; 2. the correct intake of biologically active compounds contain in meat, which have significant impacts upon human protein metabolism and so have beneficial effects on prevention of sarcopenia. This review included 62 eligible studies.
  
  
  RESULTS
  the results demonstrated that in elderly the optimum diet therapy for the sarcopenia prevention and treatment, which must aim at achieving specific metabolic goals, must recommend the consumption of 113 g of meat (220 kcal; 30 g protein) five time a week.
  
  
  CONCLUSIONS
  in a varied and balanced diet, for preventing sarcopenia, it is recommended to assume meat 4-5 times a week (white meat 2 times per week, lean red meat less than 2 times per week, processed meat less than 1 time per week), as suggested in the diet pyramid for elderly.
authors.affiliation: University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona, Pavia, Italy.. mariangela.rondanelli@unipv.it.
authors.forename: Mariangela
authors.initials: M
authors.lastname: Rondanelli
authors.affiliation: University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona, Pavia, Italy.. simoneperna@hotmail.it.
authors.forename: Simone
authors.initials: S
authors.lastname: Perna
authors.affiliation: University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona, Pavia, Italy.. milo.milena87@hotmail.it.
authors.forename: Milena Anna
authors.initials: MA
authors.lastname: Faliva
authors.affiliation: University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona, Pavia, Italy.. gabriella.peroni01@universitadipavia.it.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Peroni
authors.affiliation: University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona, Pavia, Italy.. viriainfantino@hotmail.it.
authors.forename: Vittoria
authors.initials: V
authors.lastname: Infantino
authors.affiliation: University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona, Pavia, Italy.. raffaella.pozzi@gmail.com.
authors.forename: Raffaella
authors.initials: R
authors.lastname: Pozzi
mesh_terms: D000368:Aged; D004044:Dietary Proteins / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008460:Meat; D053580:Muscle Strength; D044623:Nutrition Therapy / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D055948:Sarcopenia / Q000178:diet therapy* / Q000517:prevention & control*
chemical_list: D004044:Dietary Proteins