title: Environmental persistence of OXA-48-producing Klebsiella pneumoniae in a French intensive care unit.
abstract: The spread of carbapenemase-producing Gram-negative rods is an emerging global problem. This study describes the epidemiologic features of an outbreak caused by an environmental reservoir of OXA-48-producing Klebsiella pneumoniae caused by persistence of the bacteria during 20 months in an intensive care unit in France. This report emphasizes the importance of early environmental screening to interrupt the transmission of carbapenemase-producingEnterobacteriaceae.
authors.affiliation: Institut National de la Santé et de la Recherche Medicale, Universite of Montpellier, Nîmes, France; Department of Microbiology, Caremeau University Hospital, Nîmes, France.
authors.forename: Alix
authors.initials: A
authors.lastname: Pantel
authors.affiliation: Department of Infection Control, Caremeau University Hospital, Nîmes, France.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Richaud-Morel
authors.affiliation: Department of Infection Control, Caremeau University Hospital, Nîmes, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Cazaban
authors.affiliation: Institut National de la Santé et de la Recherche Medicale, Universite of Montpellier, Nîmes, France; Department of Microbiology, Caremeau University Hospital, Nîmes, France.
authors.forename: Nicole
authors.initials: N
authors.lastname: Bouziges
authors.affiliation: Institut National de la Santé et de la Recherche Medicale, Universite of Montpellier, Nîmes, France; Department of Infectious Diseases, Caremeau University Hospital, Nîmes, France.
authors.forename: Albert
authors.initials: A
authors.lastname: Sotto
authors.affiliation: Institut National de la Santé et de la Recherche Medicale, Universite of Montpellier, Nîmes, France; Department of Microbiology, Caremeau University Hospital, Nîmes, France. Electronic address: jean.philippe.lavigne@chu-nimes.fr.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Lavigne
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000453:epidemiology*; D004196:Disease Outbreaks; D004783:Environmental Microbiology; D005602:France; D005838:Genotype; D006801:Humans; D007362:Intensive Care Units; D007710:Klebsiella Infections / Q000453:epidemiology*; D007711:Klebsiella pneumoniae / Q000145:classification / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D001618:beta-Lactamases; C108449:oxacillinase
keywords: Carbapenemase; Enterobacteriaceae; Environment; France; Klebsiella pneumoniae; OXA-48; Persistence