title: Papillary tumor of the pineal region with extended clinical and radiologic follow-up.
abstract: BACKGROUND
  Papillary tumor of the pineal region (PTPR) is a rare neoplasm with only anecdotal data to guide the treatment. Results of treatment with surgery, radiation therapy, and chemotherapy have been reported to have varying degrees of success. Here we report a patient with a PTPR, who underwent subtotal resection, gamma knife stereotactic radiosurgery, and adjuvant temozolomide chemotherapy.
  
  
  METHODS
  During 9 years of clinical and radiographic follow-up, the patient has had regression of residual tumor and remains asymptomatic.
  
  
  CONCLUSIONS
  When gross total resection of a PTPR is not possible, treatment with gamma knife stereotactic radiosurgery and temozolomide chemotherapy may provide long-term tumor control.
authors.affiliation: Department of Neurosurgery, Roswell Park Cancer Institute, University at Buffalo, State University of New York, Buffalo, NY, USA ; Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
authors.forename: Hakeem J
authors.initials: HJ
authors.lastname: Shakir
authors.affiliation: Department of Pathology, Roswell Park Cancer Institute, University at Buffalo, State University of New York, Buffalo, NY, USA.
authors.forename: Jingxin
authors.initials: J
authors.lastname: Qiu
authors.affiliation: Department of Neurosurgery, Roswell Park Cancer Institute, University at Buffalo, State University of New York, Buffalo, NY, USA ; Department of Radiation Medicine, Roswell Park Cancer Institute, University at Buffalo, State University of New York, Buffalo, NY, USA.
authors.forename: Dheerendra
authors.initials: D
authors.lastname: Prasad
authors.affiliation: Department of Neuro oncology, Roswell Park Cancer Institute, University at Buffalo, State University of New York, Buffalo, NY ; Dent Neurologic Institute, Amherst, NY, USA.
authors.forename: Laszlo L
authors.initials: LL
authors.lastname: Mechtler
authors.affiliation: Department of Neurosurgery, Roswell Park Cancer Institute, University at Buffalo, State University of New York, Buffalo, NY, USA ; Department of Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Fenstermaker
keywords: Craniotomy; gamma knife; papillary tumor; pineal gland; radiosurgery; temozolomide