title: Serologic Evidence of Flavivirus Infections in Peridomestic Rodents in Merida, Mexico.
abstract: We conducted surveillance for flavivirus infection in peridomestic rodents in Merida, Mexico in 2011-12. We captured 161 rodents inside private residences, using Sherman traps, including 86 house mice (Mus musculus) and 75 black rats (Rattus rattus). Serum from each animal was assayed by plaque reduction neutralization test (PRNT) using two vertebrate-specific flaviviruses (Apoi and Modoc viruses) and five mosquito-borne flaviviruses (dengue 2, dengue 4, St. Louis encephalitis virus, West Nile, and yellow fever viruses). Sixty-one (37.9%) rodents had antibodies that neutralized at least one virus. Prevalences for flaviviruses were 64.0% and 15.1% for black rats and house mice, respectively. None of the PRNT90 titers exceeded 80, and often they were highest for Modoc virus. These data suggest that a subset of rodents had been infected with Modoc virus or a closely related flavivirus that was not included in the PRNT analysis.
authors.affiliation: 1 Laboratorio de Arbovirología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Calle 43 No. 613 x Calle 90 Colonia Inalámbrica CP, 97069 Mérida, Yucatán, México.
authors.forename: Nohemi
authors.initials: N
authors.lastname: Cigarroa-Toledo
authors.affiliation: 1 Laboratorio de Arbovirología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Calle 43 No. 613 x Calle 90 Colonia Inalámbrica CP, 97069 Mérida, Yucatán, México.
authors.forename: Lourdes G
authors.initials: LG
authors.lastname: Talavera-Aguilar
authors.affiliation: 1 Laboratorio de Arbovirología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Calle 43 No. 613 x Calle 90 Colonia Inalámbrica CP, 97069 Mérida, Yucatán, México.
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Baak-Baak
authors.affiliation: 1 Laboratorio de Arbovirología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Calle 43 No. 613 x Calle 90 Colonia Inalámbrica CP, 97069 Mérida, Yucatán, México.
authors.forename: Julián E
authors.initials: JE
authors.lastname: García-Rejón
authors.affiliation: 2 Departamento de Zoología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Yucatán, Carretera Mérida-Xmatkuil, Yucatán 97100, México.
authors.forename: Silvia
authors.initials: S
authors.lastname: Hernandez-Betancourt
authors.affiliation: 3 Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, 2116 Veterinary Medicine, Ames, Iowa 50011, USA.
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Blitvich
authors.affiliation: 1 Laboratorio de Arbovirología, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán, Calle 43 No. 613 x Calle 90 Colonia Inalámbrica CP, 97069 Mérida, Yucatán, México.
authors.forename: Carlos
authors.initials: C
authors.lastname: Machain-Williams
mesh_terms: D000818:Animals; D057134:Antibodies, Neutralizing / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D005416:Flavivirus / Q000276:immunology*; D018177:Flavivirus Infections / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary*; D008800:Mexico / Q000453:epidemiology; D051379:Mice; D009500:Neutralization Tests / Q000662:veterinary; D015995:Prevalence; D051381:Rats; D012376:Rodent Diseases / Q000453:epidemiology* / Q000821:virology
chemical_list: D057134:Antibodies, Neutralizing; D000914:Antibodies, Viral
keywords: Flavivirus; Mexico; Modoc virus; rodents; surveillance