title: [Portopulmonary hypertension with recurrent syncope:  a case report and review of literature].
abstract: A case of portopulmonary hypertension characterized by repeated syncope was retrospectively analyzed. Intrahepatic or extrahepatic factor-induced portal hypertension complicated with metabolic disorder of vasoactive substances, vascular pressure, inflammation, etc. may result in systolic and diastolic dysfunction of pulmonary arteries and systemic hyperdynamic circulation, the long-term effect of which can induce vascular remodeling and consequently, pulmonary hypertension. The pathogenic process is rather insidious. Pulmonary hypertension is clinically characterized by the raised average pulmonary artery pressure, normal pulmonary capillary wedge pressure and high pulmonary vascular resistance. Currently available therapeutic approaches include drug therapy targeting on pulmonary hypertension and liver transplantation.
authors.affiliation: Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Mengling
authors.initials: M
authors.lastname: Hou
authors.affiliation: Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Daoquan
authors.initials: D
authors.lastname: Peng
authors.affiliation: Department of Cardiology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Li
mesh_terms: D001794:Blood Pressure; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications / Q000175:diagnosis*; D006976:Hypertension, Pulmonary / Q000150:complications / Q000175:diagnosis*; D016031:Liver Transplantation; D013575:Syncope / Q000150:complications / Q000175:diagnosis*