title: [Chronic Duodenitis and Celiac Disease: a path between the nonspecific and the early stages of Marsh].
abstract: Given the advances in diagnosis for CD, some patients are detected with symptoms and signs of food intolerance, which have positive antibodies and autoantibodies for coeliac disease, whom present proximal bowel biopsies with chronic nonspecific duodenitis and are not associated with stages 0 and 1 Marsh. On the other hand, patients with bloating, abdominal pain, pondostatural delay, negative antibodies for CD, and chronic nonspecific duodenitis in whom removing cow's milk or gluten, the symptoms remit. There are also celiac patients with biopsies before diagnosis, with chronic nonspecific duodenitis. In this paper, we summarize three brothers with different degrees of chronic duodenitis, one with chronic nonspecific duodenitis, and two with histopathological sings of coeliac disease. It is an invitation to think that chronic nonspecific duodenitis in some patients may be an earlier manifestation of celiac disease.
authors.forename: Andrea Helena
authors.initials: AH
authors.lastname: Passera
authors.forename: Mario Luis
authors.initials: ML
authors.lastname: Passera
authors.forename: Antonio Luis
authors.initials: AL
authors.lastname: Higa
authors.forename: Maria
authors.initials: M
authors.lastname: Nuñez
authors.forename: Lucas
authors.initials: L
authors.lastname: Armando
authors.forename: Silvia
authors.initials: S
authors.lastname: Barzón
mesh_terms: D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004382:Duodenitis / Q000150:complications* / Q000175:diagnosis; D006683:HLA-DQ Antigens / Q000097:blood; D006801:Humans; D008297:Male; D011503:Transglutaminases / Q000276:immunology
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; D006683:HLA-DQ Antigens; D011503:Transglutaminases