title: Intra- and Intersession Repeatability of an Optical Quality and Intraocular Scattering Measurement System in Children.
abstract: OBJECTIVE
  To evaluate intra- and intersession repeatability of objective optical quality and intraocular scattering measurements with a double-pass system in children.
  
  
  METHODS
  Forty-two eyes of 42 children were included in the study. An optical quality analysis system (OQAS) was used to measure optical quality parameters, including modulation transfer function cutoff frequency (MTFcutoff), Strehl ratio (SR), OQAS values (OV) at 3 different contrasts and objective scatter index (OSI). Three measurement sessions with 10-min intervals were operated by the same technician, and in each session four consecutive measurements were obtained.
  
  
  RESULTS
  Mean values for MTFcutoff, SR and OSI were 46.85 ± 7.45cpd, 0.27 ± 0.06 and 0.34 ± 0.22 respectively. 1) The intraclass correlation coefficients were ranged from 0.89 to 0.97 and coefficients of variation from 0.06 to 0.16 for all the parameters in the first session; the relative repeatability were 11.1% (MTFcutoff), 22.5% (SR), 10.9% (OV100%), 16.6% (OV2%), 22.4% (OV9%) and 56.3% (OSI). Similar results were found in the second and third sessions. 2) Bland-Altman analysis showed that narrow 95% confidence intervals (compared between the first and second sessions) ranged from -5.42 to 5.28 (MTFcutoff), -0.05 to 0.07 (SR), -0.18 to 0.18 (OV100%), -0.26 to 0.29 (OV20%), -0.33 to 0.39 (OV9%) and -0.11 to 0.09 (OSI); the comparison between any two of the three sessions showed similar results.
  
  
  CONCLUSIONS
  Measurements of optical quality and intraocular scattering in children by the double-pass system showed good intra- and intersession repeatability. Retinal image quality is high and intraocular scattering is low in children.
authors.affiliation: Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Myopia Key Laboratory of the Health Ministry, Shanghai, People's Republic of China.
authors.forename: Mi
authors.initials: M
authors.lastname: Tian
authors.affiliation: Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Myopia Key Laboratory of the Health Ministry, Shanghai, People's Republic of China.
authors.forename: Huamao
authors.initials: H
authors.lastname: Miao
authors.affiliation: Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Myopia Key Laboratory of the Health Ministry, Shanghai, People's Republic of China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Shen
authors.affiliation: Center of Clinical Epidemiology and Evidence-based Medicine, Fudan University, Shanghai, People's Republic of China.
authors.forename: Jian
authors.initials: J
authors.lastname: Gao
authors.affiliation: Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Myopia Key Laboratory of the Health Ministry, Shanghai, People's Republic of China.
authors.forename: Xiaofen
authors.initials: X
authors.lastname: Mo
authors.affiliation: Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Myopia Key Laboratory of the Health Ministry, Shanghai, People's Republic of China.
authors.forename: Xingtao
authors.initials: X
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D014787:Vision Tests / Q000379:methods*; D014785:Vision, Ocular