title: Paratrimerins A and B, Two New Dimeric Monoterpene-Linked Coumarin Glycosides from the Roots and Stems of Paramignya trimera.
abstract: Two new dimeric monoterpene-linked coumarin glucosides, paratrimerins A (1) and B (2), and three known coumarins, 6-(6-hydroxy-3,7-dimethylocta-2,7-dienyl)-7-hydroxycoumarin (3), ostruthin (4), and ninhvanin (5), were isolated from the roots and stems of Paramignya trimera (OLIV.) GUILL. collected in Khanh Hoa province, Vietnam. Compound 1 comprises two 7-O-β-D-glucopyranoside coumarins linked at positions 6,6' via a 1,3,4,4-tetrasubstituted cyclohexene containing a monoterpene bridge, whereas compound 2 is a β-D-apiofuranosyl(1→6)-β-D-glucopyranosyl derivative of 1. The chemical structures of these compounds were determined by one dimensional (1D) and 2D-NMR and high resolution-electrospray ionization (HR-ESI)-MS spectroscopy.
authors.affiliation: Department of Bioactive Products, Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST).
authors.forename: Nguyen Manh
authors.initials: NM
authors.lastname: Cuong
authors.forename: Tran Thu
authors.initials: TT
authors.lastname: Huong
authors.forename: Pham Ngoc
authors.initials: PN
authors.lastname: Khanh
authors.forename: Nguyen Van
authors.initials: NV
authors.lastname: Tai
authors.forename: Vu Thi
authors.initials: VT
authors.lastname: Ha
authors.forename: Ninh The
authors.initials: NT
authors.lastname: Son
authors.forename: Bui Huu
authors.initials: BH
authors.lastname: Tai
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
mesh_terms: D003374:Coumarins / Q000032:analysis*; D006027:Glycosides / Q000032:analysis*; D039821:Monoterpenes / Q000032:analysis*; D018517:Plant Roots / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D027821:Rutaceae / Q000737:chemistry*
chemical_list: D003374:Coumarins; D006027:Glycosides; D039821:Monoterpenes; C030123:coumarin