title: Mind the gap: Signal movement through plasmodesmata is critical for the manifestation of SAR.
abstract: Systemic acquired resistance (SAR) is a plant defense response in which an initial localized infection affords enhanced pathogen resistance to distant, uninfected leaves. SAR requires efficient long-distance signaling between the infected leaf, where SAR signals are generated, and the distant uninfected leaves that receive them. A growing body of evidence indicates that the lipid transfer protein DIR1 (Defective in Induced Resistance) is an important mediator of long-distance SAR signaling. In a recent publication, we investigated if cell-to-cell movement through plasmodesmata is required for long-distance movement of DIR1 during SAR. We determined that overexpression of Plasmodesmata-Located Proteins (PDLP1 and 5) negatively impacted long-distance DIR1 movement and SAR competence, suggesting that movement through plasmodesmata contributes to long-distance signal movement during SAR.
authors.affiliation: a Department of Biology; McMaster University ; Hamilton , Ontario , Canada.
authors.forename: Philip
authors.initials: P
authors.lastname: Carella
authors.affiliation: a Department of Biology; McMaster University ; Hamilton , Ontario , Canada.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Wilson
authors.affiliation: a Department of Biology; McMaster University ; Hamilton , Ontario , Canada.
authors.forename: Robin K
authors.initials: RK
authors.lastname: Cameron
mesh_terms: D017360:Arabidopsis / Q000378:metabolism* / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D050556:Fatty Acid-Binding Proteins; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins / Q000378:metabolism; D010935:Plant Diseases / Q000382:microbiology*; D057865:Plant Immunity; D018515:Plant Leaves / Q000378:metabolism* / Q000382:microbiology; D031425:Plasmodesmata / Q000378:metabolism*; D044224:Pseudomonas syringae; D015398:Signal Transduction
chemical_list: D029681:Arabidopsis Proteins; D002352:Carrier Proteins; D050556:Fatty Acid-Binding Proteins; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins; C528450:PDLP1a protein, Arabidopsis; C586778:PDLP5 protein, Arabidopsis; C466483:dir1-1 protein, Arabidopsis; C030363:lipid transfer protein
keywords: Arabidopsis; DIR1; Pseudomonas syringae; cell-to-cell movement; phloem; plasmodesmata; systemic acquired resistance