title: Composition of the SAGA complex in plants and its role in controlling gene expression in response to abiotic stresses.
abstract: Protein complexes involved in epigenetic regulation of transcription have evolved as molecular strategies to face environmental stress in plants. SAGA (Spt-Ada-Gcn5 Acetyltransferase) is a transcriptional co-activator complex that regulates numerous cellular processes through the coordination of multiple post-translational histone modifications, including acetylation, deubiquitination, and chromatin recognition. The diverse functions of the SAGA complex involve distinct modules that are highly conserved between yeast, flies, and mammals. In this review, the composition of the SAGA complex in plants is described and its role in gene expression regulation under stress conditions summarized. Some of these proteins are likely involved in the regulation of the inducible expression of genes under light, cold, drought, salt, and iron stress, although the functions of several of its components remain unknown.
authors.affiliation: Laboratorio de Bioingeniería, Facultad de Ingeniería y Ciencias, Universidad Adolfo Ibáñez Santiago, Chile.
authors.forename: Felipe
authors.initials: F
authors.lastname: Moraga
authors.affiliation: Laboratorio de Bioingeniería, Facultad de Ingeniería y Ciencias, Universidad Adolfo Ibáñez Santiago, Chile ; Center for Applied Ecology and Sustainability Santiago, Chile.
authors.forename: Felipe
authors.initials: F
authors.lastname: Aquea
keywords: SAGA complex; abiotic stress; chromatin remodeling; histone acetyltransferase; protein complex; transcriptional coactivator