title: Laparoscopy Reveals a Diversity of Peritoneal Change in Patients with Long-Term Vintage of Peritoneal Dialysis.
abstract: BACKGROUND
  Although laparoscopy may provide more detailed morphological and histological information about peritoneal damage, its significance in patients with long vintage of peritoneal dialysis (PD) is not elucidated.
  
  
  METHODS
  Findings in 12 patients with PD vintage of 7.3 (5.0-8.4) years who had undergone laparoscopy between 2007 and 2011 were reviewed. Macroscopic (peritoneal change, hypervascular change, adhesion, encapsulation) and histopathological peritoneal findings (interstitial fibrosis, microvascular change, fibrin deposition, inflammatory cell infiltration) were scored and summed as Macro-total score (Macro-TS) and Micro-total score (Micro-TS), respectively. Factors associated with these scores and the relationship between these scores were investigated.
  
  
  RESULTS
  Neither Macro-TS nor Micro-TS were related to PD vintage (p = 0.069 and p = 0.769, respectively); moreover, Macro-TS varied from patient to patient regardless of similar PD vintage. However, Macro-TS showed a significant association with duration of acidic dialysate (p = 0.003).
  
  
  CONCLUSIONS
  Macroscopic and microscopic findings via laparoscopy may help the assessment of peritoneal damage in patients with long PD vintage.
authors.affiliation: Department of Nephrology, Japan Community Health Care Organization Osaka Hospital, Osaka, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Sasaki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Mizuno
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Iwamoto
authors.forename: Masami
authors.initials: M
authors.lastname: Imakita
authors.forename: Keiko
authors.initials: K
authors.lastname: Yasuda
authors.forename: Tomonori
authors.initials: T
authors.lastname: Kimura
authors.forename: Hiromi
authors.initials: H
authors.lastname: Rakugi
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Isaka
authors.forename: Terumasa
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D000368:Aged; D005260:Female; D005355:Fibrosis / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D010535:Laparoscopy; D017254:Leukemic Infiltration / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010537:Peritoneum / Q000098:blood supply / Q000473:pathology* / Q000601:surgery; D013997:Time Factors; D000267:Tissue Adhesions / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology