title: The Microbiota and Transgenomic Networks: Potential Implications for Maternal-Fetal Medicine.
abstract: The maternal microbiota has long been considered a potential cause for adverse perinatal outcomes. Gene expression regulators in prokaryotic and eukaryotic cells are influenced by changes in their microenvironments. We propose the novel idea that during in utero development, an adaptive and dynamic gene-regulatory cross talk might exist between the host genome and the maternal microbiota. Understanding these cross talks could increase the appreciation for the discovery of new diagnostics and therapeutics in maternal-fetal medicine.
authors.affiliation: The Perinatal Institute, Jersey Shore University Medical Center, Neptune, N.J., USA.
authors.forename: Joaquin
authors.initials: J
authors.lastname: Santolaya-Forgas
authors.forename: Ryan
authors.initials: R
authors.lastname: Townsend
authors.forename: Jacobo L
authors.initials: JL
authors.lastname: Santolaya
authors.forename: Priya
authors.initials: P
authors.lastname: Patel
authors.forename: Guadalupe
authors.initials: G
authors.lastname: Herrera-Garcia
authors.forename: V Daniel
authors.initials: VD
authors.lastname: Castracane
mesh_terms: D005260:Female; D053263:Gene Regulatory Networks; D006801:Humans; D064307:Microbiota; D010500:Perinatology; D011247:Pregnancy