title: Antifungal Substances from Streptomyces sp. A3265 Antagonistic to Plant Pathogenic Fungi.
abstract: In a previous study, we identified a Streptomyces sp., A3265, as exhibiting potent antifungal activity against various plant pathogenic fungi, including Botrytis cinerea, Colletotrichum gloeosporioides, and Rhizoctonia solani. This strain also exhibited a biocontrolling effect against ginseng root rot and damping-off disease, common diseases of ginseng and other crops. In this study, we isolated two antifungal substances responsible for this biocontrolling effect via Diaion HP-20 and Sephadex LH-20 column chromatography, medium pressure liquid chromatography, and high-performance liquid chromatography. These compounds were identified as guanidylfungin A and methyl guanidylfungin A by spectroscopic methods. These compounds exhibited potent antimicrobial activity against various plant pathogenic fungi as well as against bacteria.
authors.affiliation: Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea.
authors.forename: Nguyen
authors.initials: N
authors.lastname: Van Minh
authors.affiliation: Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea.
authors.forename: E-Eum
authors.initials: EE
authors.lastname: Woo
authors.affiliation: Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea.
authors.forename: Ji-Yul
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea.
authors.forename: Dae-Won
authors.initials: DW
authors.lastname: Kim
authors.affiliation: Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea.
authors.forename: Byung Soon
authors.initials: BS
authors.lastname: Hwang
authors.affiliation: Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea.
authors.forename: Yoon-Ju
authors.initials: YJ
authors.lastname: Lee
authors.affiliation: Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea.
authors.forename: In-Kyoung
authors.initials: IK
authors.lastname: Lee
authors.affiliation: Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea.
authors.forename: Bong-Sik
authors.initials: BS
authors.lastname: Yun
keywords: Biocontrol agent; Damping-off; Guanidylfungin; Streptomyces sp. A3265