title: Aleukemic Myeloid Sarcoma of the Breast.
abstract: Myeloid sarcoma is a solid collection of leukemic blast cells outside bone marrow. It is seen infrequently in association with overt Acute Myeloid Leukemia (AML), however, it invariably transforms into this aggressive condition. A28-year woman presented with a lump in left breast for last 2 years. Morphological and immunophenotypic results of breast mass were consistent with myeloid sarcoma. Bone marrow aspirate and biopsy were normal, however, patient died after one and a half years of diagnosis. Myeloid sarcoma at any extramedullary site heralds development of overt acute myeloid leukemia and should be appropriately managed at the time of diagnosis.
authors.affiliation: Department of Pathology and Laboratory Medicine, The Aga Khan University Hospital, Karachi-74800.
authors.forename: Muhammad Shariq
authors.initials: MS
authors.lastname: Shaikh
authors.affiliation: Department of Pathology and Laboratory Medicine, The Aga Khan University Hospital, Karachi-74800.
authors.forename: Naila
authors.initials: N
authors.lastname: Kayani
mesh_terms: D000328:Adult; D001706:Biopsy; D001940:Breast / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000473:pathology*; D023981:Sarcoma, Myeloid / Q000473:pathology*; D014463:Ultrasonography