title: Cystic Fibrosis Nutrition--Chewing the Fat.
abstract: Survival data for successive birth cohorts of cystic fibrosis infants born in the twentieth century have shown consistent improvements. More recent UK and US data suggest a plateau in improvements for clinically relevant outcomes. Better treatment of malnutrition has arguably been the most important advance in CF care, but despite this nearly a half of the UK CF population has a sub-optimal BMI. Nutritional decline typically occurs in late childhood and early adult life. Addressing poor adherence and more targeted multi-disciplinary interventions to prevent or reverse this pattern are key to achieving better outcomes for CF patients in the future.
authors.affiliation: Consultant in Paediatric Respiratory Medicine, Southampton Children's Hospital, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD, UK. Electronic address: gary.connett@uhs.nhs.uk.
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Connett
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications / Q000628:therapy*; D004035:Diet Therapy / Q000379:methods*; D056947:Enzyme Replacement Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000209:etiology / Q000628:therapy*; D010348:Patient Care Team; D010349:Patient Compliance; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D054328:Proton Pump Inhibitors
keywords: Adherence.; Body Mass Index; Cystic Fibrosis; Lean Body Mass; Nutrition