title: PPIs: between overuse and underprescription when really necessary.
abstract: Hydrochloric acid gastric secretion plays, among its primary physiological foundations, a role as protective barrier against infection with external agents from the diet and also contributes to the digestion of ingested food. However, this secretion is a critical factor shared by a number of highly prevalent diseases involving the upper gastrointestinal tract. Paradigms of such conditions include gastroduodenal peptic ulcer and gastroesophageal reflux disease.
authors.affiliation: Servicio de Gastroenterología, Hospital Universitario Ramón y Cajal. Madrid, España.
authors.forename: Carlos
authors.initials: C
authors.lastname: Martín de Argila de Prados
authors.affiliation: Hospital Universitario Ramón y Cajal.
authors.forename: Lara
authors.initials: L
authors.lastname: Aguilera Castro
authors.affiliation: Hospital Universitario Ramón y Cajal.
authors.forename: Enrique
authors.initials: E
authors.lastname: Rodríguez de Santiago
mesh_terms: D004363:Drug Utilization; D006801:Humans; D057970:Inappropriate Prescribing; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*; D013030:Spain
chemical_list: D054328:Proton Pump Inhibitors