title: Tropane alkaloids and calystegines as chemotaxonomic markers in the Solanaceae.
abstract: This study assessed the occurrence and distribution of tropane alkaloids and calystegines in genera of the family Solanaceae to identify patterns of distribution and make evolutionary inferences. A database of tropane alkaloids and calystegines occurrences was constructed from the results of a search of scientific websites and a hand search of periodicals. The terms "Solanaceae", "tropane alkaloids", and "calystegines" were used as index terms for a full-text article search unrestricted by date of publications. The number of occurrence and chemical diversity indices were calculated and cluster analysis and principal components analysis were performed. Overall, 996 occurrences were reported, 879 of tropane alkaloids (88.3%) and 117 of calystegines (11.7%). The calystegines were significantly more relevant than tropane alkaloids for characterization of distinct groups of genera on both analyses performed here. This corroborates the trend toward a chemical dichotomy observed on database analysis and somewhat reinforces the correlation between geographic distribution and occurrence of secondary metabolites, as the presence of calystegines alone (without tropane alkaloids) was only reported in genera that have South America as their center of diversity.
authors.affiliation: Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Aline G S
authors.initials: AG
authors.lastname: Pigatto
authors.affiliation: Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Carolina C
authors.initials: CC
authors.lastname: Blanco
authors.affiliation: Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Lilian A
authors.initials: LA
authors.lastname: Mentz
authors.affiliation: Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Geraldo L G
authors.initials: GL
authors.lastname: Soares
mesh_terms: D015415:Biomarkers / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D019657:Solanaceae / Q000737:chemistry* / Q000145:classification; D012991:Solanaceous Alkaloids / Q000032:analysis*; D014326:Tropanes / Q000032:analysis*
chemical_list: D015415:Biomarkers; D012991:Solanaceous Alkaloids; D014326:Tropanes; C055033:calystegin