title: Cardiovascular Implantable Electronic Device Infections: Risk Scoring and Role of Antibiotic Envelope in Prevention.
abstract: Cardiac implantable electronic device (CIED) has been increasingly used with expanding indications in patients with cardiac diseases. There is substantial evidence to suggest of their role in improving outcomes in patients with and without heart failure. Complications of the device implantation including infections are associated with increased morbidity and mortality and also substantial financial burden to the society. Several clinical characteristics have been recognized as risk factors for the occurrence of the infections. Considering that infections occur in the presence of multiple risk factors acting together, scoring systems have been developed in identifying patients at risk. Despite preventive measures, the rates of infections associated with CIEDs have increased over the last decade. Recent studies have documented the role of implantable antibiotic eluting pouches in reducing infections in patients undergoing CIED implantation. The present review will address the risk scoring systems studied and also address the role of antibiotic pouch and the recent patents in developing this technology.
authors.affiliation: 1802 S. Yakima Avenue, Suite 302, Tacoma, WA 98405, USA. nasirshariff@gmail.com.
authors.forename: Nasir
authors.initials: N
authors.lastname: Shariff
authors.forename: Tauseef
authors.initials: T
authors.lastname: Akthar
authors.forename: Eathar
authors.initials: E
authors.lastname: Razak
authors.forename: Nathan
authors.initials: N
authors.lastname: Segerson
authors.forename: David
authors.initials: D
authors.lastname: Schwartzman
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control; D053821:Cardiovascular Infections / Q000209:etiology / Q000517:prevention & control*; D017147:Defibrillators, Implantable / Q000009:adverse effects* / Q000382:microbiology; D006331:Heart Diseases / Q000628:therapy; D006333:Heart Failure / Q000150:complications / Q000628:therapy; D006801:Humans; D016459:Prosthesis-Related Infections / Q000517:prevention & control; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents