title: Sedentary behaviour patterns and arterial stiffness in a Spanish adult population - The EVIDENT trial.
abstract: OBJECTIVE
  Arterial stiffness is a contributor to the development of atherosclerosis and cardiovascular disease. The aim of the study was to analyse the relationship between sedentary behaviour and arterial stiffness in a Spanish adult population.
  
  
  METHODS
  This cross-sectional study included 1365 subjects belonging to the EVIDENT project. Physical activity and sedentary behaviour were measured objectively over 7 days using ActiGraph accelerometers. Thresholds of 10 consecutive minutes were used to estimate the daily sedentary time in bouts ≥10 min. Each interruption in sedentary time (counts/min ≥100) was considered a break. Arterial stiffness was evaluated using the B-pro device through the following indicators: radial Augmentation Index (rAIx), Ambulatory Arterial Stiffness Index (AASI), and central and peripheral pulse pressure (PP).
  
  
  RESULTS
  We found a positive relationship between central and peripheral pulse pressure (office, 24 h, awake and sleep PP) and total sedentary time. These arterial stiffness parameters were also associated with sedentary time in bouts ≥10 min. Significance disappeared in both cases, however, after adjusting for MVPA and breaks per sedentary hour. Adults who reported fewer breaks per sedentary hour (25th percentile < 2 n/day) had higher levels of AASI, awake and sleep PP.
  
  
  CONCLUSIONS
  In a medium-sized sample of adult attenders of community clinics our data showed that it seems to be important to avoid prolonged uninterrupted periods of sedentary time.
authors.affiliation: Laboratorio de Ciencias de la Actividad Física, el Deporte y la Salud, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, USACH, Chile.
authors.forename: A
authors.initials: A
authors.lastname: García-Hermoso
authors.affiliation: Universidad de Castilla-La Mancha, Health and Social Research Center, Cuenca, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Notario-Pacheco
authors.affiliation: EVIDENT Group. redIAPP: Red de Investigación en Actividades Preventivas y Promoción de la Salud (Research Network on Preventive Activities and Health Promotion), Spain.
authors.forename: J I
authors.initials: JI
authors.lastname: Recio-Rodríguez
authors.affiliation: Universidad de Castilla-La Mancha, Health and Social Research Center, Cuenca, Spain. Electronic address: Vicente.Martinez@uclm.es.
authors.forename: V
authors.initials: V
authors.lastname: Martínez-Vizcaíno
authors.affiliation: CAP Passeig de Sant Joan, Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Rodrigo de Pablo
authors.affiliation: Centro de Salud Torre Ramona, Zaragoza, Spain.
authors.forename: J F
authors.initials: JF
authors.lastname: Magdalena Belio
authors.affiliation: The Alamedilla Health Center, Castilla y León Health Service-SACYL, USAL, IBSAL, Salamanca, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Gómez-Marcos
authors.affiliation: The Alamedilla Health Center, Castilla y León Health Service-SACYL, USAL, IBSAL, Salamanca, Spain.
authors.forename: L
authors.initials: L
authors.lastname: García-Ortiz
mesh_terms: D056044:Actigraphy / Q000295:instrumentation; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D018570:Risk Assessment; D012307:Risk Factors; D057185:Sedentary Behavior; D013030:Spain / Q000453:epidemiology; D013997:Time Factors; D059289:Vascular Stiffness; D055815:Young Adult
keywords: Ambulatory arterial stiffness index; Ambulatory blood pressure monitoring; Arterial stiffness; Breaks in sedentary time; Cardiovascular risk factors