title: A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments.
abstract: Nerium oleander is a popular ornamental plant grown in many tropical and subtropical countries and in the Mediterranean region. It is dangerous because it has been shown to contain several types of cardiac glycosides, and hence can cause cardiac arrhythmias resembling digoxin in their toxicologic manifestations. We report a patient presenting to our hospital with Mobitz type II atrioventricular block after drinking herbal tea prepared from oleander leaves. Three hours after admission, a 200-mg empiric dose of digoxin-specific Fab antibody fragments was administered intravenously over 30 minutes. A 12-lead electrocardiogram (ECG) revealed sinus rhythm at the end of infusion. After 72 hours, the patient was discharged without any symptoms.
authors.affiliation: Department of Cardiology, Sivas Numune State Hospital, Sivas, Turkey.
authors.forename: Mustafa Adem
authors.initials: MA
authors.lastname: Tatlısu
authors.affiliation: Department of Cardiology, Corlu State Hospital, Tekirdag, Turkey.
authors.forename: Elif İjlal
authors.initials: Eİ
authors.lastname: Çekirdekçi
authors.affiliation: Department of Cardiology, Dr. Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, Istanbul, Turkey.
authors.forename: Şükrü
authors.initials: Ş
authors.lastname: Akyüz
authors.affiliation: Department of Cardiology, Istanbul Medipol University Faculty of Medicine, Istanbul, Turkey.
authors.forename: Zekeriya
authors.initials: Z
authors.lastname: Nurkalem
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000293:Adolescent; D054537:Atrioventricular Block / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005260:Female; D006801:Humans; D009325:Nausea / Q000209:etiology; D030007:Nerium / Q000506:poisoning*; D018515:Plant Leaves; D010939:Plant Poisoning / Q000150:complications*