title: One-stage posterior focus debridement, fusion, and instrumentation in the surgical treatment of lumbar spinal tuberculosis with kyphosis in children.
abstract: OBJECTIVE
  The purpose of this study is to investigate the clinical efficacy and feasibility of one-stage posterior focus debridement, fusion, and instrumentation in the surgical treatment of lumbar spinal tuberculosis with kyphosis in children.
  
  
  METHODS
  From December 2007 to May 2012, 13 patients (six males and seven females) suffering from lumbar spinal tuberculosis with kyphosis were admitted. All patients were treated with one-stage posterior focus debridement, fusion, and instrumentation. Then, the clinical efficacy was estimated by statistical analysis based on the data about Frankel grade, the Cobb angle of kyphosis, and erythrocyte sedimentation rate (ESR), which were collected at certain time.
  
  
  RESULTS
  The age of all patients ranged from 5 to 13 years (average, 8.8 years). Operation time ranged from 120 to 190 min (average, 165 min). Intraoperative blood loss ranged from 200 to 800 ml (average, 460 ml). All patients were followed up for 24 to 57 months postoperatively (average, 33.5 months). The Cobb angle was changed significantly between preoperation and postoperation (P < 0.05), and there was no significant loss at the last follow-up. The preoperation ESR (62.5 ± 15.7) returned to normal (16.6 ± 8.1) within 3 months postoperatively in all patients (P < 0.05). Bone fusion was achieved within 3-5 months (average, 3.5 months). In the 13 cases, no postoperative severe complications occurred and neurologic function improved in various degrees.
  
  
  CONCLUSIONS
  The outcomes of follow-up showed that one-stage posterior focus debridement, fusion, and instrumentation can be an effective treatment method for the lumbar spinal tuberculosis with kyphosis in children.
authors.affiliation: Department of Spine Surgery, Xiangya Hospital of Central South University, Changsha, 410008, China. huxiongke@163.com.
authors.forename: Xiongke
authors.initials: X
authors.lastname: Hu
authors.affiliation: Department of Spine Surgery, Xiangya Hospital of Central South University, Changsha, 410008, China. zhq9006@163.com.
authors.forename: Hongqi
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Spine Surgery, Xiangya Hospital of Central South University, Changsha, 410008, China.
authors.forename: Xinhua
authors.initials: X
authors.lastname: Yin
authors.affiliation: Department of Spine Surgery, Xiangya Hospital of Central South University, Changsha, 410008, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Spine Surgery, Xiangya Hospital of Central South University, Changsha, 410008, China.
authors.forename: Honggui
authors.initials: H
authors.lastname: Yu
authors.affiliation: Department of Spine Surgery, Xiangya Hospital of Central South University, Changsha, 410008, China.
authors.forename: Zhenhai
authors.initials: Z
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003646:Debridement / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000209:etiology / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D013123:Spinal Fusion / Q000379:methods*; D014399:Tuberculosis, Spinal / Q000150:complications / Q000601:surgery*
keywords: Children; Instrumentation; Lumbar; Posterior; Spinal tuberculosis