title: Modification research on in wall of capillary copper tube with Norland optical adhesive 68 in a double stereo PCR microfluidic chip.
abstract: In this study, a Norland optical adhesive 68 (NOA68) film, approximately 2.2 μm thick, was manufactured using ultraviolet solidified NOA68 in apparatus manufacturing film on the inwall of a capillary copper pipe, developed in our laboratory. The roughness of the inwall of capillary copper pipe was improved from Ra = 0.766 to 0.204 μm and the contact angle was improved from approximately 96° to 55°, increasing hydrophilicity. Polymerase chain reaction experiments indicated that the ratio of work pressure in the microfluidic chip before modification to that after modification was 2.71/1, indicating that the extension efficiency increased. Our results provide a basis for the construction of a microform chip based on function integration.
authors.affiliation: Institute of Laser Engineering, Beijing University of Technology, Beijing, China.
authors.forename: J
authors.initials: J
authors.lastname: Wu
authors.affiliation: Institute of Laser Engineering, Beijing University of Technology, Beijing, China.
authors.forename: F J
authors.initials: FJ
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Space Medicine Fundamentals and Application, Chinese Astronaut Science Researching and Training Center, Beijing, China.
authors.forename: C Y
authors.initials: CY
authors.lastname: Wang
authors.affiliation: College of Applied Sciences, Beijing University of Technology, Beijing, China.
authors.forename: K X
authors.initials: KX
authors.lastname: Yu
authors.affiliation: Institute of Laser Engineering, Beijing University of Technology, Beijing, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Ma
authors.affiliation: Institute of Laser Engineering, Beijing University of Technology, Beijing, China.
authors.forename: T
authors.initials: T
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Space Medicine Fundamentals and Application, Chinese Astronaut Science Researching and Training Center, Beijing, China.
authors.forename: Y H
authors.initials: YH
authors.lastname: Li
authors.affiliation: Institute of Laser Engineering, Beijing University of Technology, Beijing, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D003300:Copper / Q000737:chemistry; D044085:Microfluidics / Q000295:instrumentation* / Q000379:methods*; D016133:Polymerase Chain Reaction / Q000295:instrumentation* / Q000379:methods*
chemical_list: D003300:Copper