title: Immune Response Modulation by Vitamin D: Role in Systemic Lupus Erythematosus.
abstract: Vitamin D plays key roles as a natural immune modulator and has been implicated in the pathophysiology of autoimmune diseases, including systemic lupus erythematosus (SLE). This review presents a summary and analysis of the recent literature regarding immunoregulatory effects of vitamin D as well as its importance in SLE development, clinical severity, and possible effects of supplementation in disease treatment.
authors.affiliation: Departamento de Inmunología Clínica y Reumatología, Facultad de Medicina, Pontificia Universidad Católica de Chile , Santiago , Chile.
authors.forename: Mirentxu
authors.initials: M
authors.lastname: Iruretagoyena
authors.affiliation: Departamento de Inmunología Clínica y Reumatología, Facultad de Medicina, Pontificia Universidad Católica de Chile , Santiago , Chile.
authors.forename: Daniela
authors.initials: D
authors.lastname: Hirigoyen
authors.affiliation: Programa de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile , Santiago , Chile.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Naves
authors.affiliation: Departamento de Inmunología Clínica y Reumatología, Facultad de Medicina, Pontificia Universidad Católica de Chile , Santiago , Chile.
authors.forename: Paula Isabel
authors.initials: PI
authors.lastname: Burgos
keywords: systemic lupus erythematosus; vitamin D