title: Clinical, dermoscopic, and pathologic features of onychopapilloma: A review of 47 cases.
abstract: BACKGROUND
  Onychopapilloma is a benign neoplasm of the nail bed and the distal matrix. Although not uncommon in our experience, only up to 32 cases of this tumor have been reported in the literature.
  
  
  OBJECTIVE
  We sought to review the clinical, dermoscopic, and pathologic features of onychopapilloma.
  
  
  METHODS
  We retrospectively analyzed the clinical features of 47 patients with pathologically confirmed onychopapilloma diagnosed within the last 5 years, and reviewed the published literature.
  
  
  RESULTS
  The most common clinical presentation was longitudinal erythronychia (n = 25); followed by longitudinal leukonychia (n = 7); longitudinal melanonychia (n = 4); long splinter hemorrhages without erythronychia, leukonychia, or melanonychia (n = 8); and short splinter hemorrhages without erythronychia, leukonychia, or melanonychia (n = 3), with subungual mass (n = 47) and distal fissuring (n = 11). Pathology was consistent with acanthosis of the nail bed and distal matrix, with matrix metaplasia underlying distal subungual hyperkeratosis.
  
  
  CONCLUSIONS
  This was a retrospective analysis.
  
  
  CONCLUSIONS
  To our knowledge, our series of onychopapilloma is the largest so far. Among various clinical presentations, longitudinal erythronychia is the most common. Dermoscopy of the free edge of the nail plate showing a small subungual keratotic mass where the band reaches the nail plate margin provides a clue for the diagnosis.
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.
authors.forename: Antonella
authors.initials: A
authors.lastname: Tosti
authors.affiliation: Albert Einstein College of Medicine, Bronx, New York.
authors.forename: Samantha L
authors.initials: SL
authors.lastname: Schneider
authors.affiliation: University of the Philippines-Philippine General Hospital, St Luke's Medical Center, Global City, Taguig, Philippines.
authors.forename: Mae N
authors.initials: MN
authors.lastname: Ramirez-Quizon
authors.affiliation: Greater Miami Laser and Skin Center, Miami, Florida.
authors.forename: Martin
authors.initials: M
authors.lastname: Zaiac
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: mmiteva@med.miami.edu.
authors.forename: Mariya
authors.initials: M
authors.lastname: Miteva
mesh_terms: D046169:Dermoscopy; D005260:Female; D006801:Humans; D008297:Male; D009260:Nail Diseases / Q000473:pathology*; D010212:Papilloma / Q000473:pathology*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000473:pathology*
keywords: nail; nail bed; nail dermoscopy; nail matrix; nail pathology; nail tumor