title: Outcomes of endothelial keratoplasty in pseudophakic corneal oedema: with or without Descemet's membrane stripping.
abstract: OBJECTIVE
  To evaluate and compare outcomes of Descemet's stripping endothelial keratoplasty (DSEK) with non-DSEK (nDSEK) in pseudophakic corneal oedema (PCE).
  
  
  METHODS
  The study was a prospective, non-consecutive, comparative, interventional case series. Twenty-six patients with PCE were randomised into two groups. Group 1 comprised of those cases that had undergone conventional DSEK, and group 2 consisted of those that had nDSEK for PCE between 2010 and 2012. The data on demographics and clinical characteristics were collected from all patients. Any intraoperative and early and late postoperative complications were also noted. The primary outcome measure was postoperative functional success. Graft survival and complications were analysed as secondary outcomes.
  
  
  RESULTS
  The median best-corrected visual acuities at 6 months postoperatively in groups 1 and 2 were 0.18 (IQR 0.10-0.30) and 0.44 (IQR 0.18-0.51), respectively (p=0.11). Corneal oedema cleared in all patients. During the early postoperative period, a patient in group 2 had lenticule detachment managed by rebubbling.
  
  
  CONCLUSIONS
  nDSEK has outcomes similar to DSEK in PCE with advantages of decreased surgical time and avoidance of inadvertent pull on the posterior stromal fibres that may occur during Descemet's stripping.
authors.affiliation: Prof. Brien Holden Eye Research Centre, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: Ashik
authors.initials: A
authors.lastname: Mohamed
authors.affiliation: Cornea and Anterior Segment Services, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: Anil Raj
authors.initials: AR
authors.lastname: Ks
authors.affiliation: Cornea and Anterior Segment Services, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: Sunita
authors.initials: S
authors.lastname: Chaurasia
authors.affiliation: Cornea and Anterior Segment Services, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: Muralidhar
authors.initials: M
authors.lastname: Ramappa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015715:Corneal Edema / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000379:methods*; D004728:Endothelium, Corneal / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D019591:Pseudophakia / Q000150:complications* / Q000601:surgery; D012029:Refraction, Ocular; D016896:Treatment Outcome; D014792:Visual Acuity
keywords: Cornea; Treatment Surgery