title: [New advances in hereditary colorectal cancer].
abstract: Colorectal cancer is the most frequent malignancy in both sexes in Spain. Between 20% and 25% of affected individuals have a family history of the disease, and 5% to 6% have a germ mutation, i.e. the disease develops in the context of a hereditary syndrome. The importance of identifying patients with hereditary syndromes predisposing them to colorectal cancer lies in the possibility of applying preventive measures, screening, and more appropriate management of both patients and their families. The present article outlines the most important studies presented at the congress of the American Gastroenterological Association.
authors.affiliation: Servicio de Gastroenterología, Hospital Clínic, Barcelona, España. Electronic address: lmoreira@clinic.ub.es.
authors.forename: Leticia
authors.initials: L
authors.lastname: Moreira
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics; D015179:Colorectal Neoplasms / Q000453:epidemiology / Q000235:genetics* / Q000517:prevention & control; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000453:epidemiology / Q000235:genetics; D055088:Early Detection of Cancer; D052138:Genes, Neoplasm; D005820:Genetic Testing; D006801:Humans; D015994:Incidence; D009154:Mutation; D009386:Neoplastic Syndromes, Hereditary / Q000453:epidemiology / Q000235:genetics*; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
keywords: Adenomatous polyposis; Colorectal cancer; Cáncer colorrectal; Hereditary syndrome; Lynch syndrome; Mutación; Mutation; Poliposis adenomatosa; Poliposis serrada; Serrated polyposis; Síndrome de Lynch; Síndrome hereditario