title: Kidney transplantation in the Hispanic population.
abstract: Hispanic race and low socioeconomic status are established predictors of disparity in access to kidney transplantation. This single-center retrospective review was undertaken to determine whether Hispanic race predicted kidney transplant outcomes. A total of 720 patients underwent kidney transplantation from January 1, 2004 to December 31, 2013, including 398 Hispanic patients and 322 non-Hispanic patients. Hispanic patients were significantly younger (p < 0.0001), on hemodialysis for longer (p = 0.0018), had a greater percentage with public insurance (p < 0.0001), more commonly had diabetes as the cause of end-stage renal disease (p = 0.0167), and had a lower percentage of living donors (p = 0.0013) compared to non-Hispanic patients. There was no difference in one-, five-, and 10-yr graft (97%, 81%, and 61% vs. 95%, 76%, and 42% p = 0.18) or patient survival (98%, 90%, and 84% vs. 97%, 87%, and 69% p = 0.11) between the Hispanic and non-Hispanic recipients. Multivariate analysis identified increased recipient age and kidney donor profile index to be predictive of lower graft survival and increasing recipient age to be predictive of lower patient survival. In the largest single-center study on kidney transplantation outcomes in Hispanic patients, there is no difference in graft and recipient survival between Hispanic and non-Hispanic kidney transplant patients, and in multivariate analysis, Hispanic race is not a risk factor for graft or patient survival.
authors.affiliation: Department of Surgery, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Lea
authors.initials: L
authors.lastname: Matsuoka
authors.affiliation: Department of Surgery, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Evan
authors.initials: E
authors.lastname: Alicuben
authors.affiliation: Department of Surgery, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Karen
authors.initials: K
authors.lastname: Woo
authors.affiliation: Department of Preventive Medicine, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Shu
authors.initials: S
authors.lastname: Cao
authors.affiliation: Department of Preventive Medicine, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Susan
authors.initials: S
authors.lastname: Groshen
authors.affiliation: Department of Medicine, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Yasir
authors.initials: Y
authors.lastname: Qazi
authors.affiliation: Department of Medicine, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Miroslaw
authors.initials: M
authors.lastname: Smogorzewski
authors.affiliation: Department of Surgery, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Rick
authors.initials: R
authors.lastname: Selby
authors.affiliation: Department of Surgery, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA.
authors.forename: Sophoclis
authors.initials: S
authors.lastname: Alexopoulos
mesh_terms: D000328:Adult; D000367:Age Factors; D002140:California / Q000453:epidemiology; D016022:Case-Control Studies; D005006:Ethnicity / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006084:Graft Rejection / Q000453:epidemiology*; D006085:Graft Survival; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000706:statistics & numerical data*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Hispanic; graft survival; kidney transplant