title: Vulval Microglandular Adenosis-like Neoplasm With Chondromyxoid Stroma: Report of a Unique Case.
abstract: Microglandular adenosis of the breast is an uncommon lesion which can mimic tubular carcinoma. It is composed of small round tubules lined by a single layer of flat or cuboidal epithelial cells, often with eosinophilic colloid-like material within the lumen. The absence of a myoepithelial cell layer and preservation of basement membrane around the tubules are characteristic features. We report the first case of a vulval "neoplasm" in a 60-yr-old woman showing features identical to microglandular adenosis of the breast except for the presence of an unusual chondromyxoid stroma. This case reinforces the analogy between vulval lesions derived from anogenital mammary-like glands and breast lesions and also adds a new entity to the list of lesions arising from these glands.
authors.affiliation: Departments of Pathology (A.R., A.M, A.G.N.) Gynaecology and Obstetrics (A.O.), Princess Royal University Hospital, Orpington, Kent Department of Pathology (L.V., W.G.M.), Belfast Health and Social Care Trust, Belfast, Northern Ireland, UK.
authors.forename: Anirudha
authors.initials: A
authors.lastname: Rajguru
authors.forename: Alexandra
authors.initials: A
authors.lastname: Moulla
authors.forename: Adeyemi
authors.initials: A
authors.lastname: Ogunremi
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Venkatraman
authors.forename: W Glenn
authors.initials: WG
authors.lastname: McCluggage
authors.forename: Anitha G
authors.initials: AG
authors.lastname: Nayar
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001940:Breast; D002828:Choristoma; D005260:Female; D005348:Fibrocystic Breast Disease; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D014845:Vulvar Diseases / Q000473:pathology*
chemical_list: D015415:Biomarkers