title: Cancer Characteristics and Current Treatments of Patients with Renal Cell Carcinoma in Sweden.
abstract: METHODS
  Since the start in 2005 virtually all patients with newly diagnosed renal cell carcinoma (RCC) in Sweden are reported to the National Swedish Kidney Cancer Register (NSKCR). The register contains information on histopathology, nuclear grade, clinical stage, preoperative work-up, treatment, recurrence, and survival.
  
  
  RESULTS
  A total of 8556 patients with newly diagnosed RCC were registered in the NSKCR from 2005 to 2013 resulting in a coverage of 99% as compared to the Swedish Cancer Registry. The mean tumor size at detection decreased from 70 mm in 2005 to 64 mm in 2010. The proportion of patients who were incidentally detected increased. The proportion of patients with tumor stage T1a who underwent partial nephrectomy increased from 22% in 2005 to 56% in 2012. Similarly, the proportion of laparoscopically performed radical nephrectomies increased from 6% in 2005 to 17% in 2010. During the five years of follow-up 20% of the patients had a recurrence.
  
  
  CONCLUSIONS
  Over the last decade there has been a trend of earlier detection and less advanced tumors at detection in patients with RCC. An increasing proportion of the patients undergo laparoscopic and nephron-sparing procedures.
authors.affiliation: Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, 901 87 Umeå, Sweden ; Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institute, 171 76 Stockholm, Sweden ; Surgical Intervention Trials Unit, Nuffield Department of Surgical Sciences, University of Oxford, Oxford OX3 7DQ, UK.
authors.forename: Andreas
authors.initials: A
authors.lastname: Thorstenson
authors.affiliation: Department of Oncology, Karolinska University Hospital, Solna, 171 76 Stockholm, Sweden.
authors.forename: Ulrika
authors.initials: U
authors.lastname: Harmenberg
authors.affiliation: Department of Urology, Faculty of Medicine and Health, Örebro University, 701 82 Örebro, Sweden.
authors.forename: Per
authors.initials: P
authors.lastname: Lindblad
authors.affiliation: Department of Urology, Akademiska University Hospital, 751 85 Uppsala, Sweden.
authors.forename: Benny
authors.initials: B
authors.lastname: Holmström
authors.affiliation: Department of Urology, Sahlgrenska University Hospital, 431 45 Göteborg, Sweden.
authors.forename: Sven
authors.initials: S
authors.lastname: Lundstam
authors.affiliation: Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, 901 87 Umeå, Sweden.
authors.forename: Börje
authors.initials: B
authors.lastname: Ljungberg
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D009392:Nephrectomy; D009399:Nephrons / Q000473:pathology* / Q000601:surgery; D013548:Sweden / Q000453:epidemiology