title: Macular edema with serous retinal detachment post-phacoemulsification followed by spectral domain optical coherence tomography: a report of two cases.
abstract: BACKGROUND
  Macular edema and detachment at the first day after an uneventful cataract surgery is very rare, and has been reported previously with the use of high concentrations of intra-cameral cefuroxime. However, we hereby reported two cases of macular edema with extensive serous retinal detachment the first day after an uneventful phacoemulsification with intra-cameral injection of a standard dose of cefuroxime during the procedure.
  
  
  METHODS
  A 68-year-old female and a 63-year-old male without any special history both underwent an uneventful phacoemulsification surgery and 1 mg/0.1 ml of cefuroxime solution was injected into the anterior chamber at the end of the procedure. Macular edema with extensive serous retinal detachment around macula and optic disc area were observed the first day after surgery. Without surgical intervention, a quick recovery of the macular edema and retinal detachment was observed by spectral domain optical coherence tomography 1 week later in both cases.
  
  
  CONCLUSIONS
  We presume that the retina injury in the two cases may be attributed to cefuroxime toxicity even under a use of a standard dose. But the retinal damages are restorable and routine anti-inflammatory treatment is enough.
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sun University, Xianlie South Road No 54, Guangzhou, 510060, China. drxh81@163.com.
authors.forename: Hui
authors.initials: H
authors.lastname: Xiao
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sun University, Xianlie South Road No 54, Guangzhou, 510060, China. drliuxing@163.com.
authors.forename: Xing
authors.initials: X
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sun University, Xianlie South Road No 54, Guangzhou, 510060, China. 582803057@qq.com.
authors.forename: Xinxing
authors.initials: X
authors.lastname: Guo
mesh_terms: D000368:Aged; D000867:Anterior Chamber; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D002444:Cefuroxime / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006801:Humans; D008269:Macular Edema / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000009:adverse effects / Q000379:methods*; D012163:Retinal Detachment / Q000175:diagnosis* / Q000209:etiology; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents; D002444:Cefuroxime