title: Plasma Membrane Repair: A Central Process for Maintaining Cellular Homeostasis.
abstract: Plasma membrane repair is a conserved cellular response mediating active resealing of membrane disruptions to maintain homeostasis and prevent cell death and progression of multiple diseases. Cell membrane repair repurposes mechanisms from various cellular functions, including vesicle trafficking, exocytosis, and endocytosis, to mend the broken membrane. Recent studies increased our understanding of membrane repair by establishing the molecular machinery contributing to membrane resealing. Here, we review some of the key proteins linked to cell membrane repair.
authors.affiliation: Department of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio.
authors.forename: Alisa D
authors.initials: AD
authors.lastname: Blazek
authors.affiliation: Department of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio.
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Paleo
authors.affiliation: Department of Physiology and Cell Biology, Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio noah.weisleder@osumc.edu.
authors.forename: Noah
authors.initials: N
authors.lastname: Weisleder
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000378:metabolism* / Q000473:pathology; D006706:Homeostasis; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D012038:Regeneration; D015398:Signal Transduction
chemical_list: D008565:Membrane Proteins