title: Synaptosome-associated protein 25 (SNAP25) synthesis in terminal buttons of mouse motor neuron.
abstract: Previously, we formulated the hypothesis of compartmentalized protein synthesis in axons of motor neurons. In the axon hillock, along the entire length of the axon and in its ending, specific proteins are locally synthesized, which ensure the function of each compartment. In support of this hypothesis, in this work we studied the local protein synthesis in mouse motor nerve ending.
authors.affiliation: Kazan State Medical University, ul. Butlerova 49, Kazan, 420012, Tatarstan, Russia.
authors.forename: R R
authors.initials: RR
authors.lastname: Islamov
authors.affiliation: Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, ul. Lobachevskogo 2/31, Kazan, 420111, Russia. samid75@mail.ru.|Kazan (Volga Region) Federal University, ul. Kremlevskaya 18, Kazan, 420008, Tatarstan, Russia. samid75@mail.ru.
authors.forename: D V
authors.initials: DV
authors.lastname: Samigullin
authors.affiliation: Kazan (Volga Region) Federal University, ul. Kremlevskaya 18, Kazan, 420008, Tatarstan, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Rizvanov
authors.affiliation: Kazan (Volga Region) Federal University, ul. Kremlevskaya 18, Kazan, 420008, Tatarstan, Russia.
authors.forename: N I
authors.initials: NI
authors.lastname: Bondarenko
authors.affiliation: Kazan State Medical University, ul. Butlerova 49, Kazan, 420012, Tatarstan, Russia.|Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, ul. Lobachevskogo 2/31, Kazan, 420111, Russia.|Kazan (Volga Region) Federal University, ul. Kremlevskaya 18, Kazan, 420008, Tatarstan, Russia.
authors.forename: E E
authors.initials: EE
authors.lastname: Nikolskiy
mesh_terms: D000818:Animals; D018920:Coculture Techniques; D005089:Exocytosis / Q000502:physiology; D049452:Green Fluorescent Proteins / Q000008:administration & dosage / Q000378:metabolism; D008564:Membrane Potentials; D008810:Mice, Inbred C57BL; D008839:Microelectrodes; D008856:Microscopy, Fluorescence; D009046:Motor Neurons / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000294:innervation; D017729:Presynaptic Terminals / Q000378:metabolism*; D012333:RNA, Messenger / Q000008:administration & dosage / Q000378:metabolism; D034741:RNA, Small Interfering / Q000008:administration & dosage; D050825:Synaptosomal-Associated Protein 25 / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D012333:RNA, Messenger; D034741:RNA, Small Interfering; C494209:Snap25 protein, mouse; D050825:Synaptosomal-Associated Protein 25; D049452:Green Fluorescent Proteins