title: Polyaromatic Profluorescent Nitroxide Probes with Enhanced Photostability.
abstract: Novel profluorescent mono- and bis-isoindoline nitroxides linked to napthalimide and perylene diimide structural cores are described. These nitroxide-fluorophore probes display strongly suppressed fluorescence in comparison to their corresponding non-radical diamagnetic methoxyamine derivatives. The perylene-based probe possessing two isoindoline systems tethered through ethynyl linkages was shown to be the most photostable in solution, demonstrating significantly enhanced longevity over the 9,10-bis(phenylethynyl)anthracene fluorophore used in previous profluorescent nitroxide probes.
authors.affiliation: ARC Centre of Excellence for Free Radical Chemistry and Biotechnology, School of Chemistry, Physics and Mechanical Engineering, Faculty of Science and Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, QLD 4001 (Australia).|Defence Materials Technology Centre, Level 2 Wakefield Street, Hawthorne, VIC 3122 (Australia).
authors.forename: Vanessa C
authors.initials: VC
authors.lastname: Lussini
authors.affiliation: ARC Centre of Excellence for Free Radical Chemistry and Biotechnology, School of Chemistry, Physics and Mechanical Engineering, Faculty of Science and Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, QLD 4001 (Australia).
authors.forename: James P
authors.initials: JP
authors.lastname: Blinco
authors.affiliation: ARC Centre of Excellence for Free Radical Chemistry and Biotechnology, School of Chemistry, Physics and Mechanical Engineering, Faculty of Science and Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, QLD 4001 (Australia). k.fairfull-smith@qut.edu.au.
authors.forename: Kathryn E
authors.initials: KE
authors.lastname: Fairfull-Smith
authors.affiliation: ARC Centre of Excellence for Free Radical Chemistry and Biotechnology, School of Chemistry, Physics and Mechanical Engineering, Faculty of Science and Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, QLD 4001 (Australia). s.bottle@qut.edu.au.|Defence Materials Technology Centre, Level 2 Wakefield Street, Hawthorne, VIC 3122 (Australia). s.bottle@qut.edu.au.
authors.forename: Steven E
authors.initials: SE
authors.lastname: Bottle
keywords: fluorescence; fluorescent probes; nitroxides; photooxidation; radicals