title: Primary Gingival Tuberculosis Diagnosed Based on Genetic Identification.
abstract: A case of primary gingival tuberculosis in a 71-year-old Japanese woman is herein presented. A serous saliva culture was positive for tuberculosis, and we recognized that the origin of the tuberculosis infection was the gingiva based on the genetic identification in gingival biopsy tissue. The definitive diagnosis was facilitated by the genetic identification, a useful modern tool for diagnosing infectious diseases. The location and clinical presentation of this lesion were unusual, which underlines the importance of considering tuberculosis in the differential diagnosis of oral lesions that affect the gingiva.
authors.affiliation: Respiratory Medicine, National Hospital Organization, National Kochi Hospital, Japan.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Okano
authors.forename: Shiomi
authors.initials: S
authors.lastname: Yoshida
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Shinohara
authors.forename: Naoki
authors.initials: N
authors.lastname: Takahashi
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Naito
authors.forename: Kozo
authors.initials: K
authors.lastname: Kagawa
authors.forename: Hisanori
authors.initials: H
authors.lastname: Machida
authors.forename: Nobuo
authors.initials: N
authors.lastname: Hatakeyama
authors.forename: Akihiko
authors.initials: A
authors.lastname: Ohno
authors.forename: Takayuki
authors.initials: T
authors.lastname: Wada
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Ogushi
mesh_terms: D000368:Aged; D000995:Antitubercular Agents / Q000008:administration & dosage*; D001706:Biopsy; D004269:DNA, Bacterial / Q000302:isolation & purification*; D003937:Diagnosis, Differential; D004977:Ethambutol / Q000008:administration & dosage; D005260:Female; D005882:Gingival Diseases / Q000175:diagnosis* / Q000382:microbiology*; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D011718:Pyrazinamide / Q000008:administration & dosage; D012293:Rifampin / Q000008:administration & dosage; D016896:Treatment Outcome; D014393:Tuberculosis, Oral / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents; D004269:DNA, Bacterial; D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin