title: Isolation of an NDM-5-producing ST16 Klebsiella pneumoniae from a Dutch patient without travel history abroad, August 2015.
abstract: A New Delhi Metallo-beta-lactamase-5 (NDM-5)-producing ST16 Klebsiella pneumoniae strain was isolated from a Dutch patient in a long-term care facility without recent travel history abroad. Core genome multilocus sequence typing (cgMLST) revealed that the Dutch isolate was clonally related to isolates detected in four patients in Denmark in 2014. Public health experts and clinicians need to be informed; repetitive screening may be needed in patients without known risk factors for carbapenemases-producing Enterobacteriaceae who have undergone antibiotic treatment.
authors.affiliation: Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
authors.forename: Erik
authors.initials: E
authors.lastname: Bathoorn
authors.forename: John W
authors.initials: JW
authors.lastname: Rossen
authors.forename: Mariëtte
authors.initials: M
authors.lastname: Lokate
authors.forename: Alexander W
authors.initials: AW
authors.lastname: Friedrich
authors.forename: Anette M
authors.initials: AM
authors.lastname: Hammerum
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004269:DNA, Bacterial / Q000235:genetics; D005838:Genotype; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D007711:Klebsiella pneumoniae / Q000145:classification / Q000201:enzymology* / Q000235:genetics* / Q000302:isolation & purification; D008134:Long-Term Care; D008875:Middle Aged; D058885:Multilocus Sequence Typing; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1
keywords: CPE; Klebsiella pneumoniae; NDM; surveillance