title: Plastid control of abaxial-adaxial patterning.
abstract: Translational regulation, exerted by the cytosolic ribosome, has been shown to participate in the establishment of abaxial-adaxial polarity in Arabidopsis thaliana: many hypomorphic and null alleles of genes encoding proteins of the cytosolic ribosome enhance the leaf polarity defects of asymmetric leaves1 (as1) and as2 mutants. Here, we report the identification of the SCABRA1 (SCA1) nuclear gene, whose loss-of-function mutations also enhance the polarity defects of the as2 mutants. In striking contrast to other previously known enhancers of the phenotypes caused by the as1 and as2 mutations, we found that SCA1 encodes a plastid-type ribosomal protein that functions as a structural component of the 70S plastid ribosome and, therefore, its role in abaxial-adaxial patterning was not expected.
authors.affiliation: Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Mateo-Bonmatí
authors.affiliation: Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.
authors.forename: Rubén
authors.initials: R
authors.lastname: Casanova-Sáez
authors.affiliation: Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.
authors.forename: Víctor
authors.initials: V
authors.lastname: Quesada
authors.affiliation: Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.
authors.forename: Andrea
authors.initials: A
authors.lastname: Hricová
authors.affiliation: Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.
authors.forename: Héctor
authors.initials: H
authors.lastname: Candela
authors.affiliation: Instituto de Bioingeniería, Universidad Miguel Hernández, Campus de Elche, 03202 Elche, Spain.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Micol
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics; D000067696:Ataxin-1 / Q000235:genetics; D018506:Gene Expression Regulation, Plant / Q000235:genetics; D009154:Mutation / Q000235:genetics; D010641:Phenotype; D018515:Plant Leaves / Q000235:genetics / Q000502:physiology; D018087:Plastids / Q000235:genetics*; D012269:Ribosomal Proteins / Q000235:genetics
chemical_list: D029681:Arabidopsis Proteins; D000067696:Ataxin-1; D012269:Ribosomal Proteins