title: Major publications in the critical care pharmacotherapy literature: January-December 2014.
abstract: OBJECTIVE
  Nine recently published articles and one guideline with important implications for critical care pharmacy practice are summarized.
  
  
  CONCLUSIONS
  The Critical Care Pharmacotherapy Literature Update (CCPLU) group includes more than 40 experienced critical care pharmacists across the United States. Group members monitor 29 peer-reviewed journals on an ongoing basis to identify literature relevant to pharmacy practice in the critical care setting. After evaluation by CCPLU group members, selected articles are chosen for summarization and distribution to group members nationwide based on applicability to practice, relevance, and study design and strength. Hundreds of relevant articles were evaluated by the group in 2014, of which 114 were summarized and disseminated to CCPLU group members. From among those 114 publications, 10 deemed to be of particularly high utility to the critical care practitioner were selected for inclusion in this review for their potential to change practice or reinforce current evidence-based practice. One of the selected articles presents updated recommendations on the management of patients with atrial fibrillation (AF); the other 9 address topics such as albumin replacement in patients with severe sepsis, use of enteral statins for acute respiratory distress syndrome, fibrinolysis for patients with intermediate-risk pulmonary embolism, the use of unfractionated heparin versus bivalirudin for primary percutaneous coronary intervention, and early protocol-based care for septic shock.
  
  
  CONCLUSIONS
  There were many important additions to the critical care pharmacotherapy literature in 2014, including a joint guideline for the management of AF and reports of clinical trials.
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Day
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Michaelia
authors.initials: M
authors.lastname: Cucci
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Molly E
authors.initials: ME
authors.lastname: Droege
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Jenna M
authors.initials: JM
authors.lastname: Holzhausen
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Bridgette
authors.initials: B
authors.lastname: Kram
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Shawn
authors.initials: S
authors.lastname: Kram
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Mehrnaz
authors.initials: M
authors.lastname: Pajoumand
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Christine R
authors.initials: CR
authors.lastname: Parker
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Mona K
authors.initials: MK
authors.lastname: Patel
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Peitz
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Alia
authors.initials: A
authors.lastname: Poore
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Charles J
authors.initials: CJ
authors.lastname: Turck
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Megan A
authors.initials: MA
authors.lastname: Van Berkel
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Adrian
authors.initials: A
authors.lastname: Wong
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Amanda
authors.initials: A
authors.lastname: Zomp
authors.affiliation: Sarah A. Day, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Doctors Hospital OhioHealth, Columbus, OH. Michaelia Cucci, Pharm.D., BCPS, is Pharmacy Clinical Specialist-Critical Care, Pharmacy Department, Lakewood Hospital, Lakewood, OH. Molly E. Droege, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgery, Orthopedics, and Trauma, UC Health-University of Cincinnati Medical Center, Cincinnati, OH. Jenna M. Holzhausen, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Critical Care, Beaumont Hospital, Royal Oak, MI. Bridgette Kram, Pharm.D., BCPS, is Clinical Pharmacist, Department of Pharmacy, Duke University Medical Center, Durham, NC. Shawn Kram, Pharm.D., BCPS, is Clinical Pharmacist, Medical and Cardiothoracic ICUs, Department of Pharmacy, Duke University Medical Center. Mehrnaz Pajoumand, Pharm.D., is Clinical Specialist, Trauma Critical Care, University of Maryland Medical Center, Baltimore. Christine R. Parker, Pharm.D., BCPS, is Clinical Pharmacy Specialist, Surgical Critical Care, New York-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY. Mona K. Patel, Pharm.D., is Clinical Pharmacy Manager, Surgical Intensive Care Unit, New York-Presbyterian Hospital, Columbia University Medical Center, New York. Gregory J. Peitz, Pharm.D., is Adult Intensive Care Pharmacy Coordinator, Nebraska Medicine, Nebraska Medical Center, Omaha. Alia Poore, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Critical Care, Fairview Hospital, Cleveland, OH. Charles J Turck, Pharm.D., BCPS, is President and CEO, ScientiaCME, LLC, and Scientia Perpetuam, LLC, Highwood, IL. Megan A. Van Berkel, Pharm.D., BCPS, is Clinical Pharmacy Specialist-Emergency Department, Department of Pharmacy, Methodist LeBohneur Healthcare Methodist University Hospital, Memphis, TN. Adrian Wong, Pharm.D., BCPS, is Critical Care Clinical Pharmacist, MountainView Hospital, Las Vegas, NV. Amanda Zomp, Pharm.D., BCPS, is Clinical Pharmacist, Critical Care, Department of Pharmacy Services,
authors.forename: Megan A
authors.initials: MA
authors.lastname: Rech
mesh_terms: D003422:Critical Care; D004358:Drug Therapy; D006801:Humans; D010380:Peer Review; D010506:Periodicals as Topic / Q000706:statistics & numerical data*; D011642:Publications / Q000706:statistics & numerical data