title: Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015.
abstract: Increased febrile reactions in Australian children from one influenza vaccine brand in 2010 diminished confidence in influenza immunisation, highlighting the need for improved vaccine safety surveillance. AusVaxSafety, a national vaccine safety surveillance system collected adverse events in young children for 2015 influenza vaccine brands in real time through parent/carer reports via SMS/email. Weekly cumulative data on 3,340 children demonstrated low rates of fever (4.4%) and medical attendance (1.1%). Fever was more frequent with concomitant vaccination.
authors.affiliation: National Centre for Immunisation Research and Surveillance, The Children's Hospital at Westmead, NSW, Australia.
authors.forename: Alexis
authors.initials: A
authors.lastname: Pillsbury
authors.forename: Patrick
authors.initials: P
authors.lastname: Cashman
authors.forename: Alan
authors.initials: A
authors.lastname: Leeb
authors.forename: Annette
authors.initials: A
authors.lastname: Regan
authors.forename: Darren
authors.initials: D
authors.lastname: Westphal
authors.forename: Tom
authors.initials: T
authors.lastname: Snelling
authors.forename: Christopher
authors.initials: C
authors.lastname: Blyth
authors.forename: Nigel
authors.initials: N
authors.lastname: Crawford
authors.forename: Nicholas
authors.initials: N
authors.lastname: Wood
authors.forename: Kristine
authors.initials: K
authors.lastname: Macartney
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D001315:Australia / Q000453:epidemiology; D001499:Bayes Theorem; D040421:Cell Phone; D002675:Child, Preschool; D034742:Electronic Mail; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D007223:Infant; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000009:adverse effects*; D007251:Influenza, Human / Q000517:prevention & control*; D008297:Male; D010290:Parents; D011159:Population Surveillance / Q000379:methods*; D011446:Prospective Studies; D012621:Seasons; D060145:Text Messaging; D014611:Vaccination
chemical_list: D007252:Influenza Vaccines
keywords: Australia; Influenza; active surveillance; vaccine safety