title: The relationship between insomnia with short sleep duration is associated with hypercholesterolemia: a cross-sectional study.
abstract: OBJECTIVE
  To examine the association between insomnia with short sleep duration and hypercholesterolemia in Taiwanese adults.
  
  
  BACKGROUND
  Previous studies mostly focused on the association between sleep duration and hyperlipidemia, but the results were not consistent. Besides, very few studies extensively examined the association between insomnia and hypercholesterolemia. This study hypothesized that insomnia with short sleep duration is associated with hypercholesterolemia.
  
  
  METHODS
  Secondary data analysis. This study analysed the latest database of the cross-sectional Nutrition and Health Survey in Taiwan which was released on 2011 (data collected between 2005-2008) and collected data using stratified three-staged probability sampling design.
  
  
  METHODS
  This study analysed 1533 participants aged between 19-64 (733 males and 800 females) and used logistic regression model to calculate the odds ratio and the 95% confidence interval of insomnia with short sleep duration to hypercholesterolemia. Controlled confounders included age, gender, sample weight, body mass index, waist circumference, fasting plasma glucose, hypertension and diabetes.
  
  
  RESULTS
  Insomnia with 5-6 hours of sleep duration was significantly associated with hypercholesterolemia. The odds ratio of mild insomnia or moderate/severe insomnia with 5-6 hours of sleep duration to hypercholesterolemia was higher, compared with the reference group (without insomnia and >6 hours of sleep duration).
  
  
  CONCLUSIONS
  Insomnia with short sleep duration was associated with increased odds of hypercholesterolemia. Caregivers in clinical practice should watch out for the effect brought by this novel factor.
authors.affiliation: School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.|Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan.
authors.forename: Chia-Ling
authors.initials: CL
authors.lastname: Lin
authors.affiliation: School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.|School of Nursing, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
authors.forename: Yu-Hsia
authors.initials: YH
authors.lastname: Tsai
authors.affiliation: School of Nursing, College of Medicine, National Taiwan University, Taipei, Taiwan.
authors.forename: Mei Chang
authors.initials: MC
authors.lastname: Yeh
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D012892:Sleep Deprivation / Q000209:etiology*; D007319:Sleep Initiation and Maintenance Disorders / Q000209:etiology*; D013624:Taiwan; D013997:Time Factors; D055815:Young Adult
keywords: adult; hypercholesterolemia; insomnia; nursing; sleep duration