title: Immune recovery uveitis in a patient with previously undiagnosed cytomegalovirus retinitis.
abstract: A 40-year-old man presented to the emergency service of the Department of Ophthalmology, Fundación Oftalmológica de Santander, Floridablanca, Colombia, with blurred vision in his right eye. Anamnesis revealed that he also had newly diagnosed stage C HIV. He had recently started highly active antiretroviral therapy (HAART). Examination disclosed intraocular inflammation, along with plain white peripheral non-exudative lesions with sparse haemorrhaging. The differential diagnosis included cytomegalovirus (CMV) retinitis and immune recovery uveitis (IRU). On follow-up, the patient's left eye presented with decreased visual acuity and increased vitreous haze. A vitrectomy with vitreous tap was performed for microbiological studies. PCR for CMV in the vitreous sample was negative. The patient was discharged with the final diagnosis of IRU. In HIV patients with uveitis, the knowledge of characteristic signs and symptoms of particular entities such as opportunistic infections and IRU will enable the clinician to give the appropriate treatment.
authors.affiliation: Fundación Oftalmologica de Santander, Floridablanca, Colombia.
authors.forename: Carlos Mario
authors.initials: CM
authors.lastname: Rangel
authors.affiliation: Department of Ophthalmology, Fundación Oftalmológica de Santander (FOSCAL)/Universidad Autónoma de Bucaramanga, Floridablanca, Santander, Colombia.
authors.forename: Angélica M
authors.initials: AM
authors.lastname: Prada
authors.affiliation: Department of Ophthalmology, Fundación Oftalmologica de Santander, Floridablanca, Santander, Colombia.
authors.forename: Clara
authors.initials: C
authors.lastname: Varon
authors.affiliation: Instituto Universitario Fernández-Vega. Universidad de Oviedo.
authors.forename: Jesus
authors.initials: J
authors.lastname: Merayo-Lloves
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000276:immunology; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D017726:Cytomegalovirus Retinitis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000150:complications* / Q000276:immunology; D008297:Male; D014605:Uveitis / Q000276:immunology / Q000821:virology*