title: Successful treatment of an adult with symptomatic attention deficit, hyperactivity, and impulsivity after temporal lobe resection: case report.
abstract: Attention deficit hyperactivity disorder (ADHD) is defined by inattentiveness, impulsivity, and/or hyperactivity and mandatorily requires an onset in childhood. Structural or functional anatomical abnormalities have mostly been found in the prefrontal cortex, the corpus callosum, the striatum, and the cerebellum. We here present the case of an adult woman who developed severe symptoms analogous to ADHD after right temporal lobectomy. Surgery had been necessary because of a large temporobasal arterio-venous malformation (AVM). The patient's childhood and personal history before surgery had been without any indication of ADHD or any other mental disorder. Because of her distinct and impairing symptoms of ADHD, we initiated off-label methylphenidate treatment, achieving strong reduction in the symptoms. This proves further similarity of her symptomatic disorder to ADHD and supports a role of the right temporal lobe in ADHD.
authors.affiliation: Department of Neurology, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany. r_untucht@gmx.net.|Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Würzburg, Germany. r_untucht@gmx.net.
authors.forename: Robert
authors.identifier: http://orcid.org/0000-0002-3287-5878
authors.initials: R
authors.lastname: Untucht
authors.affiliation: Department of Psychiatry, Psychosomatics and Psychotherapy, Goethe-University Frankfurt, Frankfurt am Main, Germany.|Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, Würzburg, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Reif
mesh_terms: D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy* / Q000209:etiology*; D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007175:Impulsive Behavior; D008774:Methylphenidate / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D013702:Temporal Lobe / Q000601:surgery*
chemical_list: D000697:Central Nervous System Stimulants; D008774:Methylphenidate
keywords: Methylphenidate; Secondary ADHD; Symptomatic ADHD; Temporal lobe; Temporal lobectomy