title: Central Apneas and REM Sleep Behavior Disorder as an Initial Presentation of Multiple System Atrophy.
abstract: We present the case of a patient with multiple system atrophy who presented with central apnea as the only sleep disordered breathing, associated with REM behavior disorder and restless legs syndrome. This presentation of the disease is unusual and probably reflects more widespread involvement at the onset. With this case, we show the importance of considering this kind of disease in the differential diagnosis of central sleep apnea syndromes.
authors.affiliation: Respiratory Medicine, La Paz Hospital, Autónoma University of Madrid, idiPAZ, CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.
authors.forename: Aldara
authors.initials: A
authors.lastname: Garcia-Sanchez
authors.affiliation: Respiratory Medicine, La Paz Hospital, Autónoma University of Madrid, idiPAZ, CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: Fernandez-Navarro
authors.affiliation: Respiratory Medicine, La Paz Hospital, Autónoma University of Madrid, idiPAZ, CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Garcia-Rio
mesh_terms: D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019578:Multiple System Atrophy / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D059906:Neuroimaging; D017286:Polysomnography; D020187:REM Sleep Behavior Disorder / Q000150:complications* / Q000175:diagnosis; D020182:Sleep Apnea, Central / Q000150:complications* / Q000175:diagnosis
keywords: REM behavior disorder; central apnea; multiple system atrophy; neurodegenerative disorders