title: The management of autoimmunity in patients with cholestatic liver diseases.
abstract: Cholestatic liver diseases are rare diseases that often lead to cirrhosis and its consequent complications. In addition to liver-related morbidity, patients with cholestatic liver diseases often suffer from autoimmune diseases that affect several organs and tissues. The robust and efficient data collection and collaboration between hepatologists and rheumatologists have led to significant advancements in understanding the relationship between the cholestatic liver diseases and associated autoimmune diseases. In this paper, we discuss the cholestatic liver diseases (primary biliary cirrhosis, primary sclerosing cholangitis and immunoglobulin G4 associated cholangitis) and associated autoimmune diseases.
authors.affiliation: a 1 Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Ahmad H
authors.initials: AH
authors.lastname: Ali
authors.affiliation: a 1 Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Carey
authors.affiliation: a 1 Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ, USA.|b 2 Arizona State University, College of Health Solutions, Phoenix, AZ, USA.
authors.forename: Keith D
authors.initials: KD
authors.lastname: Lindor
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D015551:Autoimmunity; D002446:Celiac Disease / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D015209:Cholangitis, Sclerosing / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology*; D018450:Disease Progression; D019693:Hepatitis, Autoimmune / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood* / Q000276:immunology; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D010195:Pancreatitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology; D017285:Polymyositis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D011379:Prognosis; D045743:Scleroderma, Diffuse / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D012871:Skin Diseases / Q000150:complications / Q000209:etiology; D013959:Thyroid Diseases / Q000150:complications / Q000628:therapy
chemical_list: D007074:Immunoglobulin G
keywords: IgG4-associated cholangitis; antimitochondrial antibody; autoimmune; primary biliary cirrhosis; primary sclerosing cholangitis