title: Herpes Zoster as a Predictor of HIV Infection in Taiwan: A Population-Based Study.
abstract: This study aimed to investigate the association between herpes zoster (HZ) and human immunodeficiency virus (HIV). Data were retrieved from the Longitudinal Health Insurance Databases (LHID 2005 and 2010), Taiwan. The International Classification of Diseases, 9th Revision, Clinical Modification [ICD-9-CM] codes were used to identify Hz from 2001-2004. Identification of HIV infection was from 2005-2010. The hazard ratios of HIV among herpes zoster infected and non-herpes zoster infected patients were estimated using multiple Cox proportional hazard model. In general, 19685 participants were identified with Hz. The HIV incidence rates (per 104 person-months) in herpes zoster infected and non-infected patients were 0.191(95% CI 0.130-0.280) and 0.079 (95% CI 0.074-0.084), respectively while the hazard ratio (HR) of HIV among infected individuals was 3.518 (95% CI 2.375-5.211). This study concludes that herpes zoster could be considered as a predictor of HIV infection especially among Asian populations, hence it is vital to test herpes zoster infected individuals for HIV antibodies.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC.|School of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC.|Institute of Medicine and School of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC.
authors.forename: Yuan-Ti
authors.initials: YT
authors.lastname: Lee
authors.affiliation: Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City 40201, Taiwan.
authors.forename: Oswald Ndi
authors.initials: ON
authors.lastname: Nfor
authors.affiliation: Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City 40201, Taiwan.
authors.forename: Disline Manli
authors.initials: DM
authors.lastname: Tantoh
authors.affiliation: Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City 40201, Taiwan.
authors.forename: Jing-Yang
authors.initials: JY
authors.lastname: Huang
authors.affiliation: Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City 40201, Taiwan.
authors.forename: Wen-Yuan
authors.initials: WY
authors.lastname: Ku
authors.affiliation: Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City 40201, Taiwan.
authors.forename: Shu-Yi
authors.initials: SY
authors.lastname: Hsu
authors.affiliation: Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City 40201, Taiwan.
authors.forename: Pei-Chieh
authors.initials: PC
authors.lastname: Ko
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Nantou Hospital, Ministry of Health and Welfare, Nantou, Taiwan, ROC.
authors.forename: Hung-Chang
authors.initials: HC
authors.lastname: Hung
authors.affiliation: Office of Physical Education, Chung Yuan Christian University, 200, Chung Pei Rd, Chung Li, Taiwan.
authors.forename: Cheng-Feng
authors.initials: CF
authors.lastname: Jan
authors.affiliation: Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City 40201, Taiwan.|Department of Family and Community Medicine, Chung Shan Medical University Hospital, Taichung City 40201, Taiwan.
authors.forename: Yung-Po
authors.initials: YP
authors.lastname: Liaw
mesh_terms: D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D006562:Herpes Zoster / Q000150:complications*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D013624:Taiwan / Q000453:epidemiology