title: Spinal Surgery and Abrupt Intrathecal Baclofen Withdrawal.
abstract: Abrupt cessation of intrathecal baclofen can lead to a serious withdrawal syndrome. The anesthesiologist must be prepared to avoid intraoperative interruption of baclofen delivery before starting spinal surgery and to recognize and treat the symptoms of baclofen withdrawal in the immediate postoperative period.
authors.affiliation: From the Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University Medical Center, Stanford, California.
authors.forename: Karl
authors.initials: K
authors.lastname: Zheng
authors.forename: Jay B
authors.initials: JB
authors.lastname: Brodsky
mesh_terms: D001418:Baclofen / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015918:Infusion Pumps, Implantable; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*; D009128:Muscle Spasticity / Q000188:drug therapy; D013131:Spine / Q000601:surgery*; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen