title: The biphasic bioresorbable scaffold (Trufit(®)) in the osteochondral knee lesions: long-term clinical and MRI assessment in 30 patients.
abstract: BACKGROUND
  Chondral or osteochondral defects have been reported in 60-67 % of patients in studies reporting knee arthroscopies. The surgical management of chondral and osteochondral defects (OCD's) of the articular surface of the knee joint remains a controversial topic. Osteochondral injuries can be treated with transfer cartilage procedure and with implantation of biodegradable scaffolds. For patients over 50 years old with largest osteochondral lesions, we prefer to use the biodegradable scaffold, like Trufit(®) plug (Smith & Nephew, Andover, MA). The purpose of this study is to evaluate the outcome of this series of surgical procedure with Trufit.
  
  
  METHODS
  In our institute, the Trufit was used for the treatment of one or more focal osteochondral lesions of the femoral condyles positive MRI with or without concomitant ligamentous or meniscal pathology. We reviewed 30 patients with mean age of 60.57 years (range 32-79 years) with a clinical and imaging control at 6, 12, 24 and 48 months of follow-up.
  
  
  RESULTS
  The clinical evaluation has shown the good outcome. The MRI conducted has shown the progressive partial integration of the scaffolds.
  
  
  CONCLUSIONS
  The results obtained indicate a clear improvement of the clinical symptoms and slowing joint degeneration. The clinical and imaging results confirm that the Trufit constitutes a valid surgical alternative in case of focal osteochondral.
authors.affiliation: IInd Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Dell'Osso
authors.affiliation: IInd Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Bottai
authors.affiliation: IInd Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Bugelli
authors.affiliation: IInd Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Manisco
authors.affiliation: IInd Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Cazzella
authors.affiliation: IInd Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Celli
authors.affiliation: IInd Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Guido
authors.affiliation: IInd Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy. s.giannotti@med.unipi.it.
authors.forename: S
authors.initials: S
authors.lastname: Giannotti
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D000368:Aged; D001182:Arthroscopy; D002358:Cartilage, Articular / Q000293:injuries / Q000502:physiology / Q000601:surgery*; D005260:Female; D006801:Humans; D007718:Knee Injuries / Q000000981:diagnostic imaging / Q000601:surgery*; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012038:Regeneration; D012189:Retrospective Studies; D054457:Tissue Scaffolds; D016896:Treatment Outcome
keywords: Knee; Osteochondral lesions; Scaffold