title: Recent Updates on the Association Between Alzheimer's Disease and Vascular Dementia.
abstract: The two most common forms of dementia are Alzheimer's disease (AD) followed by vascular dementia (VaD), together accounting for a whopping 60-80% of total dementia cases worldwide. Even though these diseases are recognized as 'common', they still remain underdiagnosed. Recent research suggests that AD and VaD are closely intertwined. The symptoms of AD and VaD can be similar and the two conditions can occur simultaneously. A large number of patients diagnosed with AD have also been reported with VaD-caused brain damage. Moreover, both the diseases have been reported to have similar risk factors. The overlap between these diseases is important because the lifestyle changes and medications prescribed to curb one of these diseases may also help curb the other. In the present review, we present an inclusive outline of parallelism between AD and VaD by exploring the potential commonalities at the mechanistic and therapeutic levels.
authors.affiliation: King Fahd Medical Research Center, King Abdulaziz University, P. O. Box 80216, Jeddah 21589, Saudi Arabia. gashraf@kau.edu.sa.
authors.forename: Ghulam M
authors.initials: GM
authors.lastname: Ashraf
authors.forename: Sandesh
authors.initials: S
authors.lastname: Chibber
authors.lastname: Mohammad
authors.forename: Syed K
authors.initials: SK
authors.lastname: Zaidi
authors.forename: Shams
authors.initials: S
authors.lastname: Tabrez
authors.forename: Ausaf
authors.initials: A
authors.lastname: Ahmad
authors.forename: Shazi
authors.initials: S
authors.lastname: Shakil
authors.forename: Gohar
authors.initials: G
authors.lastname: Mushtaq
authors.forename: Saleh S
authors.initials: SS
authors.lastname: Baeesa
authors.affiliation: prof.makamal@lycos.com.
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Kamal
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D000818:Animals; D015140:Dementia, Vascular / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D006801:Humans; D012307:Risk Factors