title: Resistance to Antibiotics and Antifungal Medicinal Products: Can Complementary and Alternative Medicine Help Solve the Problem in Common Infection Diseases? The Introduction of a Dutch Research Consortium.
abstract: The increase of antibiotic resistance worldwide, rising numbers of deaths and costs associated with this, and the fact that hardly any new antimicrobial drugs have been developed during the last decade have increased the interest in Complementary and Alternative Medicine (CAM) therapeutic interventions, if proven safe and effective. Observational studies on clinical CAM practices demonstrate positive effects of treatment of infections with CAM therapies (clinical effects, patient satisfaction) in combination with small percentages of antibiotics prescription. However, Cochrane reviews and other studies demonstrate that in most instances the quality of clinical trials on CAM treatment of infections is currently too low to provide sufficient evidence. Therefore a Dutch consortium on (in vitro and clinical) scientific research on CAM and antibiotic resistance has been formed. The aim and objective of the consortium is to establish an enduring partnership and to develop expertise to further develop and investigate safe and effective CAM treatments for infectious diseases of humans (and animals). A first ongoing project on the development of safe and effective biobased CAM antimycotics in women with (recurrent) vaginal candidiasis infection is introduced.
authors.affiliation: University of Applied Sciences, 2333 CK Leiden, Netherlands ; Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol, Bristol BS8 2PS, UK.
authors.forename: Esther T
authors.initials: ET
authors.lastname: Kok
authors.affiliation: Department of Healthcare and Nutrition, Louis Bolk Institute, 2972 LA Driebergen, Netherlands ; Department of Health Sciences, Mid Sweden University, 871 31 Sundsvall, Sweden ; National Information and Knowledge Centre on Integrative Medicine (NIKIM), Amsterdam, Netherlands.
authors.forename: Miek C
authors.initials: MC
authors.lastname: Jong
authors.affiliation: University of Applied Sciences, 2333 CK Leiden, Netherlands ; Naturalis Biodiversity Center, 2333 CR Leiden, Netherlands.
authors.forename: Barbara
authors.initials: B
authors.lastname: Gravendeel
authors.affiliation: University of Applied Sciences, 2333 CK Leiden, Netherlands.
authors.forename: Willem B
authors.initials: WB
authors.lastname: Van Leeuwen
authors.affiliation: University of Applied Sciences, 2333 CK Leiden, Netherlands ; Department of Healthcare and Nutrition, Louis Bolk Institute, 2972 LA Driebergen, Netherlands.
authors.forename: Erik W
authors.initials: EW
authors.lastname: Baars