title: [Proton pump inhibitors (PPI): may be not as harmless as believed].
abstract: Proton pump inhibitors (PPIs) are among the most widely prescribed medications worldwide and their use is increasing. Their efficiency has been proven and the short term tolerance is good with few reversible side effects. However concerns about possible long term side effects continue to arise. This article reviews proven and potential side effects associated with PPI especially on the long term use.
authors.forename: O
authors.initials: O
authors.lastname: Reinberg
mesh_terms: D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004347:Drug Interactions; D019317:Evidence-Based Medicine; D050723:Fractures, Bone / Q000139:chemically induced; D005759:Gastroenteritis / Q000139:chemically induced; D005764:Gastroesophageal Reflux / Q000188:drug therapy*; D006801:Humans; D009203:Myocardial Infarction / Q000139:chemically induced; D009395:Nephritis, Interstitial / Q000139:chemically induced; D011230:Precancerous Conditions / Q000139:chemically induced; D054328:Proton Pump Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors