title: Predicting cardiovascular disease from handgrip strength: the potential clinical implications.
abstract: The measurement of handgrip strength has proven prognostic value for all-cause and cardiovascular death, and for cardiovascular disease. It is also an important indicator of frailty and vulnerability. The measurement of handgrip strength may be most useful in the context of multi-morbidity, where it may be a simple tool to identify the individual at particularly high risk of adverse outcomes, who may benefit from closer clinical attention. Research into dietary, exercise, and pharmacologic strategies to increase muscle strength is ongoing. Important issues will be the feasibility and sustainability of increases in muscle strength, and whether these increases translate into clinical benefit.
authors.affiliation: a Population Health Research Institute , McMaster University and Hamilton Health Sciences , Hamilton , Canada.
authors.forename: Darryl P
authors.initials: DP
authors.lastname: Leong
authors.affiliation: a Population Health Research Institute , McMaster University and Hamilton Health Sciences , Hamilton , Canada.
authors.forename: Koon K
authors.initials: KK
authors.lastname: Teo
mesh_terms: D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D019468:Disease Management; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D011379:Prognosis; D018570:Risk Assessment; D055948:Sarcopenia / Q000503:physiopathology / Q000517:prevention & control
keywords: cardiovascular; frailty; handgrip strength; multi-morbidity; muscle strength; prognosis; sarcopenia