title: Seventh INTERMACS annual report: 15,000 patients and counting.
abstract: The seventh annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) summarizes the first 9 years of patient enrollment. The Registry includes >15,000 patients from 158 participating hospitals. Trends in device strategy, patient profile at implant and survival are presented. Risk factors for mortality with continuous-flow pumps are updated, and the major causes/modes of death are presented. The adverse event burden is compared between eras, and health-related quality of life is reviewed. A detailed analysis of outcomes after mechanical circulatory support for ambulatory heart failure is presented. Recent summary data from PediMACS and MedaMACS is included. With the current continuous-flow devices, survival at 1 and 2 years is 80% and 70%, respectively.
authors.affiliation: Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: jkirklin@uab.edu.
authors.forename: James K
authors.initials: JK
authors.lastname: Kirklin
authors.affiliation: Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.
authors.forename: David C
authors.initials: DC
authors.lastname: Naftel
authors.affiliation: Department of Surgery, University of Michigan, Ann Arbor, Michigan.
authors.forename: Francis D
authors.initials: FD
authors.lastname: Pagani
authors.affiliation: Department of Surgery, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Kormos
authors.affiliation: Department of Medicine, Brigham & Women's Hospital, Boston, Massachusetts.
authors.forename: Lynne W
authors.initials: LW
authors.lastname: Stevenson
authors.affiliation: Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.
authors.forename: Elizabeth D
authors.initials: ED
authors.lastname: Blume
authors.affiliation: Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.
authors.forename: Susan L
authors.initials: SL
authors.lastname: Myers
authors.affiliation: Division of Cardiovascular Diseases, Advanced Technologies and Surgery Branch, National Heart Lung and Blood Institute, Bethesda, Maryland.
authors.forename: Marissa A
authors.initials: MA
authors.lastname: Miller
authors.affiliation: Division of Cardiovascular Diseases, Advanced Technologies and Surgery Branch, National Heart Lung and Blood Institute, Bethesda, Maryland.
authors.forename: J Timothy
authors.initials: JT
authors.lastname: Baldwin
authors.affiliation: Department of Medicine, Cleveland Clinic Foundation Lerner College of Medicine, Cleveland, Ohio.
authors.forename: James B
authors.initials: JB
authors.lastname: Young
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000847:Annual Reports as Topic; D005260:Female; D006333:Heart Failure / Q000601:surgery*; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D012042:Registries; D055815:Young Adult
keywords: INTERMACS; advanced heart failure; destination therapy; mechanical support; ventricular assist device