title: Palladium-Catalyzed Aerobic Aminooxygenation of Alkenes for Preparation of Isoindolinones.
abstract: A palladium-catalyzed intramolecular isoindolinone-forming aminooxygenation of alkenes with 1 atm of oxygen as oxidant is reported. A variety of functionalized alkenes and carboxylic acids can be used, and high yields were observed. Preliminary mechanistic studies revealed that the aminooxygenation products were formed through the oxidation of a C-Pd(II) species using a strong oxidant, peroxide, which is generated in situ from a Pd(OAc)2/bpy/O2/HOAc catalytic system.
authors.affiliation: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, China.
authors.forename: Xuezhen
authors.initials: X
authors.lastname: Kou
authors.affiliation: School of Chemical and Environmental Engineering, Shanghai Institute of Technology , 100 Haiquan Road, Shanghai 201418, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Li
authors.affiliation: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Wu
authors.affiliation: School of Chemical and Environmental Engineering, Shanghai Institute of Technology , 100 Haiquan Road, Shanghai 201418, China.
authors.forename: Xinghua
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, China.
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Yang
authors.affiliation: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, China.
authors.forename: Wanbin
authors.initials: W
authors.lastname: Zhang