title: Hemoperitoneum Due to Warfarin Toxicity Presenting as Intestinal Obstruction.
abstract: The patients on anticoagulation therapy especially warfarin can develop gastrointestinal bleed, gum bleeding, hematuria or ecchymosis. Rarely do such patients present with hemoperitoneum producing symptoms. Hemoperitoneum can produce shock, cause compression symptoms or may even be fatal. Such patients can be managed conservatively or may need surgical exploration for ongoing bleeding or decompression. We had a patient taking warfarin who presented with hemoperitoneum producing intestinal symptoms. The patient was managed conservatively with fluid and blood product replacement and stopping warfarin. The benefits of thromboprophylaxis and the risks of bleeding should be carefully evaluated and the dose of warfarin carefully adjusted.
authors.affiliation: Department of General Surgery, Services Hospital, Lahore.
authors.forename: Huma Sabir
authors.initials: HS
authors.lastname: Khan
authors.affiliation: Department of General Surgery, Services Hospital, Lahore.
authors.forename: Awais
authors.initials: A
authors.lastname: Naeem
authors.affiliation: Department of General Surgery, Services Hospital, Lahore.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Ayyaz
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006465:Hemoperitoneum / Q000139:chemically induced*; D006801:Humans; D019934:International Normalized Ratio; D007415:Intestinal Obstruction / Q000209:etiology*; D008297:Male; D016896:Treatment Outcome; D014859:Warfarin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin