title: Palmar-plantar erythrodysesthesia associated with capecitabine chemotherapy: a case report.
abstract: We report a case of a 62 year-old patient who developed Palmar-plantar erythrodysesthesia upon receiving four cycles of capacitabine-based chemotherapy. She was on post surgical adjuvant treatment for invasive well differentiated adenocarcinoma of the colon. The clinical and therapeutic aspects of this chemotherapeutic adverse effect are discussed.
authors.affiliation: Department of Pharmacology &Toxicology, Moi University School of Medicine, Eldoret, Kenya ; Department of Haematology and Oncology, Moi University School of Medicine, Eldoret, Kenya.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Kigen
authors.affiliation: Department of Pharmacology &Toxicology, Moi University School of Medicine, Eldoret, Kenya ; Department of Haematology and Oncology, Moi University School of Medicine, Eldoret, Kenya.
authors.forename: Naftali
authors.initials: N
authors.lastname: Busakhala
authors.affiliation: Department of Haematology and Oncology, Moi University School of Medicine, Eldoret, Kenya ; Department of Medicine, Moi University School of Medicine, Eldoret, Kenya.
authors.forename: Evangeline
authors.initials: E
authors.lastname: Njiru
authors.affiliation: Department of Haematology and Oncology, Moi University School of Medicine, Eldoret, Kenya ; Department of Medicine, Moi University School of Medicine, Eldoret, Kenya.
authors.forename: Fredrick
authors.initials: F
authors.lastname: Chite
authors.affiliation: Indiana University Simon Cancer Center, Barnhill Dr, Indianapolis, United States.
authors.forename: Patrick
authors.initials: P
authors.lastname: Loehrer
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects* / Q000627:therapeutic use; D000069287:Capecitabine / Q000009:adverse effects* / Q000627:therapeutic use; D003110:Colonic Neoplasms / Q000188:drug therapy / Q000473:pathology; D005260:Female; D060831:Hand-Foot Syndrome / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008875:Middle Aged
chemical_list: D000964:Antimetabolites, Antineoplastic; D000069287:Capecitabine
keywords: Kenya; Palmar-plantar erythrodysesthesia; capecitabine