title: Energy metabolism, liver and kidney function in adolescent marathon runners.
abstract: BACKGROUND
  To study parameters of energy metabolism, liver and kidney function in adolescent runners completing a standard 42·2-km marathon run.
  
  
  METHODS
  Observational field study.
  
  
  METHODS
  Fifty adolescents (30 healthy males and 20 healthy females) aged between 13 and 17 years participated in the study. All participants underwent routine medical screening. Blood samples were taken before, at the end and 24 h after a competitive marathon to investigate parameters of metabolism, liver and kidney function.
  
  
  RESULTS
  Forty-seven runners completed the race with a mean finishing time of 4 h 57 min 24 s (range: 3 h 17 min 09 s to 6 h 14 min 01 s). None of the participants experienced an adverse medical event during or postmarathon. Findings indicate predominant lipid oxidation during and postmarathon, signs of minor hepatic injury and only transiently reduced kidney function caused by marathon running in adolescents.
  
  
  CONCLUSIONS
  The observed findings are very similar to those reported in healthy adults. There is no evidence of liver or kidney injury in adolescent runners participating in a standard marathon run.
authors.affiliation: Department of Sport Science, Medical Section, University of Innsbruck, Innsbruck, Austria.|Department of Applied Science and Engineering, Khon Kaen University, Nong Khai Campus, Nong Khai, Thailand.
authors.forename: Natthapon
authors.initials: N
authors.lastname: Traiperm
authors.affiliation: Department of Sport Science, Medical Section, University of Innsbruck, Innsbruck, Austria.
authors.forename: Hannes
authors.initials: H
authors.lastname: Gatterer
authors.affiliation: Department of Applied Science and Engineering, Khon Kaen University, Nong Khai Campus, Nong Khai, Thailand.
authors.forename: Prapapimon
authors.initials: P
authors.lastname: Pariwat
authors.affiliation: Department of Sport Science, Medical Section, University of Innsbruck, Innsbruck, Austria.
authors.forename: Martin
authors.initials: M
authors.lastname: Burtscher
mesh_terms: D000293:Adolescent; D000410:Alanine Transaminase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D001219:Aspartate Aminotransferases / Q000378:metabolism; D056352:Athletes; D001663:Bilirubin / Q000378:metabolism; D001786:Blood Glucose / Q000378:metabolism; D001806:Blood Urea Nitrogen; D008076:Cholesterol, HDL / Q000378:metabolism; D008078:Cholesterol, LDL / Q000378:metabolism; D003404:Creatinine / Q000378:metabolism; D004734:Energy Metabolism; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D007677:Kidney Function Tests; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism*; D008111:Liver Function Tests; D008297:Male; D012420:Running / Q000502:physiology*; D014280:Triglycerides / Q000378:metabolism; D014527:Uric Acid / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D014527:Uric Acid; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin
keywords: Adolescents; biochemical parameters; metabolism; running