title: Reducing Sitting Time After Stroke: A Phase II Safety and Feasibility Randomized Controlled Trial.
abstract: OBJECTIVE
  To test the safety, feasibility, and effectiveness of reducing sitting time in stroke survivors.
  
  
  METHODS
  Randomized controlled trial with attention-matched controls and blinded assessments.
  
  
  METHODS
  Community.
  
  
  METHODS
  Stroke survivors (N=35; 22 men; mean age, 66.9±12.7y).
  
  
  METHODS
  Four counseling sessions over 7 weeks with a message of sit less and move more (intervention group) or calcium for bone health (attention-matched control group).
  
  
  METHODS
  Measures included safety (adverse events, increases in pain, spasticity, or fatigue) and feasibility (adherence to trial protocol). Secondary measures included time spent sitting (including in prolonged bouts ≥30min), standing, and stepping as measured by the thigh-worn inclinometer (7d, 24h/d protocol) and time spent in physical activity of at least moderate intensity as measured by a triaxial accelerometer. The Multimedia Activity Recall for Children and Adults was used to describe changes in use of time.
  
  
  RESULTS
  Thirty-three participants completed the full protocol. Four participants reported falls during the intervention period with no other adverse events. From a baseline average of 640.7±99.6min/d, daily sitting time reduced on average by 30±50.6min/d (95% confidence interval [CI], 5.8-54.6) in the intervention group and 40.4±92.5min/d in the control group (95% CI, 13.0-93.8). Participants in both groups also reduced their time spent in prolonged sitting bouts (≥30min) and increased time spent standing and stepping.
  
  
  CONCLUSIONS
  Our protocol was both safe and feasible. Participants in both groups spent less time sitting and more time standing and stepping postintervention, but outcomes were not superior for intervention participants. Attention matching is desirable in clinical trials and may have contributed to the positive outcomes for control participants.
authors.affiliation: Alliance for Research in Exercise, Nutrition and Activity, Sansom Institute of Health Research, University of South Australia, Adelaide, SA, Australia; Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia. Electronic address: Coralie.english@newcastle.edu.au.
authors.forename: Coralie
authors.initials: C
authors.lastname: English
authors.affiliation: School of Public Health, The University of Queensland, Brisbane, QLD, Australia; Baker International Diabetes Institute Heart and Diabetes Institute, Melbourne, VIC, Australia; School of Physiotherapy, Curtin University, Perth, WA, Australia.
authors.forename: Genevieve N
authors.initials: GN
authors.lastname: Healy
authors.affiliation: Alliance for Research in Exercise, Nutrition and Activity, Sansom Institute of Health Research, University of South Australia, Adelaide, SA, Australia.
authors.forename: Tim
authors.initials: T
authors.lastname: Olds
authors.affiliation: Alliance for Research in Exercise, Nutrition and Activity, Sansom Institute of Health Research, University of South Australia, Adelaide, SA, Australia.
authors.forename: Gaynor
authors.initials: G
authors.lastname: Parfitt
authors.affiliation: Faculty of Management, Bournemouth University, Poole, Dorset, United Kingdom; College of Sport and Exercise, Victoria University, Melbourne, VIC, Australia.
authors.forename: Erika
authors.initials: E
authors.lastname: Borkoles
authors.affiliation: Alliance for Research in Exercise, Nutrition and Activity, Sansom Institute of Health Research, University of South Australia, Adelaide, SA, Australia.
authors.forename: Alison
authors.initials: A
authors.lastname: Coates
authors.affiliation: Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia.
authors.forename: Sharon
authors.initials: S
authors.lastname: Kramer
authors.affiliation: Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia.
authors.forename: Julie
authors.initials: J
authors.lastname: Bernhardt
mesh_terms: D000058:Accidental Falls / Q000706:statistics & numerical data; D000368:Aged; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D062405:Motivational Interviewing; D009043:Motor Activity / Q000502:physiology*; D010865:Pilot Projects; D011187:Posture / Q000502:physiology*; D055502:Secondary Prevention; D020521:Stroke / Q000503:physiopathology / Q000517:prevention & control; D000071939:Stroke Rehabilitation
keywords: Exercise; Rehabilitation; Sedentary lifestyle; Stroke; Walking