title: Paraplegia after contrast media application: a transient or devastating rare complication? Case report.
abstract: The authors report the case of a 76-year-old man with a spinal dural arteriovenous fistula. The patient suffered from sudden repeated reversible paraplegia after spinal digital subtraction angiography as well as CT angiography. Neurotoxicity of contrast media (CM) is the most probable cause for this repeated short-lasting paraplegia. Intolerance to toxicity of CM to the vulnerable spinal cord is rare, and probably depends on the individual patient. This phenomenon is transient and can occur after both intraarterial and intravenous CM application.
authors.affiliation: Departments of 1 Neurosurgery and.
authors.forename: Dorothee
authors.initials: D
authors.lastname: Mielke
authors.affiliation: Neuroradiology, Georg-August-University, Göttingen; and.
authors.forename: Kai
authors.initials: K
authors.lastname: Kallenberg
authors.affiliation: Department of Neuroradiology, HELIOS Hospital Berlin-Buch, Berlin, Germany.
authors.forename: Marius
authors.initials: M
authors.lastname: Hartmann
authors.affiliation: Departments of 1 Neurosurgery and.
authors.forename: Veit
authors.initials: V
authors.lastname: Rohde
mesh_terms: D000368:Aged; D015901:Angiography, Digital Subtraction / Q000009:adverse effects*; D020785:Central Nervous System Vascular Malformations / Q000000981:diagnostic imaging*; D000072226:Computed Tomography Angiography / Q000009:adverse effects*; D003287:Contrast Media / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010264:Paraplegia / Q000139:chemically induced*; D013118:Spinal Cord Diseases / Q000000981:diagnostic imaging*
chemical_list: D003287:Contrast Media
keywords: BBB = blood-brain barrier; CM = contrast media; CT angiography; CTA = CT angiography; DSA = digital subtraction angiography; MRC = Medical Research Council; complication; contrast media application; dAVF = dural arteriovenous fistula; digital subtraction angiography; paraplegia