title: Successful Multidisciplinary Therapy for Small Cell Carcinomas Arising from the Extrahepatic Bile Duct.
abstract: A 74-year-old man was diagnosed with small cell carcinoma arising from the extrahepatic bile duct according to a histological examination of the biopsy specimen obtained during endoscopic retrograde cholangiopancreatography. Additionally, bulky hilar lymphadenopathy was observed, and the patient was treated with the combination of radiation and chemotherapy (cisplatin and irinotecan). Post-therapy, he underwent pancreaticoduodenectomy. The histological examination of the resected specimen revealed no residual cancer cells in the bile duct wall and a small amount of cancer cells in only a single lymph node. Due to this multidisciplinary therapy, the patient showed no signs of recurrence 12 months postoperatively.
authors.affiliation: The Third Department of Internal Medicine, Kansai Medical University, Japan.
authors.forename: Koh
authors.initials: K
authors.lastname: Nakamaru
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Ikeura
authors.forename: Hideaki
authors.initials: H
authors.lastname: Miyoshi
authors.forename: Makoto
authors.initials: M
authors.lastname: Takaoka
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Danbara
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Horitani
authors.forename: Masataka
authors.initials: M
authors.lastname: Masuda
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Yamada
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Uemura
authors.forename: Hideyoshi
authors.initials: H
authors.lastname: Toyokawa
authors.forename: Sohei
authors.initials: S
authors.lastname: Satoi
authors.forename: A-Hon
authors.initials: AH
authors.lastname: Kwon
authors.forename: Kazuichi
authors.initials: K
authors.lastname: Okazaki
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D017734:Bile Ducts, Extrahepatic / Q000000981:diagnostic imaging; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D018288:Carcinoma, Small Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002945:Cisplatin / Q000008:administration & dosage; D003135:Common Bile Duct / Q000473:pathology*; D006801:Humans; D000077146:Irinotecan; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D016577:Pancreaticoduodenectomy / Q000379:methods; D011838:Radiation-Sensitizing Agents / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D011838:Radiation-Sensitizing Agents; D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin