title: In-Hospital Pneumococcal Polysaccharide Vaccination Is Associated With Detection of Pneumococcal Vaccine Serotypes in Adults Hospitalized for Community-Acquired Pneumonia.
abstract: During an etiology study of adults hospitalized for pneumonia, in which urine specimens were examined for serotype-specific pneumococcal antigen detection, we observed that some patients received 23-valent pneumococcal polysaccharide vaccine before urine collection. Some urine samples became positive for specific vaccine pneumococcal serotypes shortly after vaccination, suggesting false-positive test results.
authors.affiliation: Vanderbilt University School of Medicine , Nashville, Tennessee ; Geriatric Research Education Clinical Center , VA Tennessee Valley , Nashville.
authors.forename: Carlos G
authors.initials: CG
authors.lastname: Grijalva
authors.affiliation: Northwestern University-Feinberg School of Medicine.
authors.forename: Richard G
authors.initials: RG
authors.lastname: Wunderink
authors.affiliation: Vanderbilt University School of Medicine , Nashville, Tennessee.
authors.forename: Yuwei
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Vanderbilt University School of Medicine , Nashville, Tennessee.
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Williams
authors.affiliation: Rush University School of Medicine.
authors.forename: Robert
authors.initials: R
authors.lastname: Balk
authors.affiliation: John H. Stroger, Jr. Hospital of Cook County , Chicago, Illinois.
authors.forename: Sherene
authors.initials: S
authors.lastname: Fakhran
authors.affiliation: Northwestern University-Feinberg School of Medicine.
authors.forename: D Mark
authors.initials: DM
authors.lastname: Courtney
authors.affiliation: Emory University School of Medicine , Atlanta, Georgia.
authors.forename: Evan J
authors.initials: EJ
authors.lastname: Anderson
authors.affiliation: Northwestern University-Feinberg School of Medicine.
authors.forename: Chao
authors.initials: C
authors.lastname: Qi
authors.affiliation: University of Tennessee Health Science Center/Saint Thomas Health , Nashville.
authors.forename: Christopher
authors.initials: C
authors.lastname: Trabue
authors.affiliation: University of Utah School of Medicine , Salt Lake City.
authors.forename: Andrew T
authors.initials: AT
authors.lastname: Pavia
authors.affiliation: Centers for Disease Control and Prevention , Atlanta, Georgia.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Moore
authors.affiliation: Centers for Disease Control and Prevention , Atlanta, Georgia.
authors.forename: Seema
authors.initials: S
authors.lastname: Jain
authors.affiliation: Vanderbilt University School of Medicine , Nashville, Tennessee.
authors.forename: Kathryn M
authors.initials: KM
authors.lastname: Edwards
authors.affiliation: Vanderbilt University School of Medicine , Nashville, Tennessee.
authors.forename: Wesley H
authors.initials: WH
authors.lastname: Self
keywords: antigen; pneumococcal conjugate vaccine; pneumonia; serotype; urine