title: Computational Fluid Dynamics-Based Design Optimization Method for Archimedes Screw Blood Pumps.
abstract: An optimization method suitable for improving the performance of Archimedes screw axial rotary blood pumps is described in the present article. In order to achieve a more robust design and to save computational resources, this method combines the advantages of the established pump design theory with modern computer-aided, computational fluid dynamics (CFD)-based design optimization (CFD-O) relying on evolutionary algorithms and computational fluid dynamics. The main purposes of this project are to: (i) integrate pump design theory within the already existing CFD-based optimization; (ii) demonstrate that the resulting procedure is suitable for optimizing an Archimedes screw blood pump in terms of efficiency. Results obtained in this study demonstrate that the developed tool is able to meet both objectives. Finally, the resulting level of hemolysis can be numerically assessed for the optimal design, as hemolysis is an issue of overwhelming importance for blood pumps.
authors.affiliation: Laboratory of Fluid Dynamics & Technical Flows, University of Magdeburg "Otto von Guericke, Magdeburg, Germany.
authors.forename: Hai
authors.initials: H
authors.lastname: Yu
authors.affiliation: Laboratory of Fluid Dynamics & Technical Flows, University of Magdeburg "Otto von Guericke, Magdeburg, Germany.
authors.forename: Gábor
authors.initials: G
authors.lastname: Janiga
authors.affiliation: Laboratory of Fluid Dynamics & Technical Flows, University of Magdeburg "Otto von Guericke, Magdeburg, Germany.
authors.forename: Dominique
authors.identifier: http://orcid.org/0000-0001-7599-9574
authors.initials: D
authors.lastname: Thévenin
mesh_terms: D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design; D006353:Heart-Assist Devices; D018056:Hemorheology; D006801:Humans; D057446:Hydrodynamics; D008955:Models, Cardiovascular
keywords: Computational fluid dynamics; Hemolysis; Left ventricular assist device; Pump design; Pump optimization; Screw blood pump