title: Novel mode of liquid-phase microextraction: A magnetic stirrer as the extractant phase holder.
abstract: In the present study, a novel configuration of liquid-phase microextraction was proposed, in which a magnetic stirrer with a groove was used as the extractant phase holder. It was termed as magnetic stirrer liquid-phase microextraction. In this way, the stability of the organic solvent was much improved under high stirring speed; the extraction efficiency was enhanced due to the enormously enlarged contact area between the organic solvent and aqueous phase. The extraction performance of the magnetic stirrer liquid-phase microextraction was studied using chlorobenzenes as the probe analytes. A wide linearity range (20 pg/mL to 200 ng/mL) with a satisfactory linearity coefficient (r(2) > 0.998) was obtained. Limits of detection ranged from 9.0 to 12.0 pg/mL. Good reproducibility was achieved with intra- and inter-day relative standard deviations <4.8%. The proposed magnetic stirrer liquid-phase microextraction was simple, environmentally friendly and efficient; compared to single-drop microextraction, it had obvious advantages in terms of reproducibility and extraction efficiency. It is a promising miniaturized liquid-phase technology for real applications.
authors.affiliation: Department of Chemistry, Wuhan University, Wuhan, 430072, China.
authors.forename: Zhi-Yuan
authors.initials: ZY
authors.lastname: Luo
authors.affiliation: Department of Chemistry, Wuhan University, Wuhan, 430072, China.
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Liu
authors.affiliation: Department of Chemistry, Wuhan University, Wuhan, 430072, China.
authors.forename: Zhi-Guo
authors.initials: ZG
authors.lastname: Shi
keywords: Chlorobenzene; Gas chromatography with mass spectrometry; Liquid-phase microextraction; Magnetic stirrers