title: Higher prevalence of oral human papillomavirus infection in HIV-positive than HIV-negative Thai men and women.
abstract: OBJECTIVE
  This study was designed to investigate the prevalence of oral human papillomavirus (HPV) infection among HIV-positive and HIV-negative Thai men and women.
  
  
  METHODS
  Participants including men who have sex with men (MSM) and heterosexual women were enrolled at the Thai Red Cross Anonymous Clinic in Bangkok. History taking and oral examination were performed by three independent dentists after calibration. HPV infection was evaluated from oral rinse with mouthwash collected at the time of examination. HPV typing was performed by PCR and nucleic acid hybridization to detect thirty-seven HPV DNA genotypes using Linear Array(®) HPV Genotyping Test (Roche Molecular System, Inc.).
  
  
  RESULTS
  244 subjects were enrolled in the study, consisted of 187 HIV-positive (51.9% women and 48.1% MSM) and 57 HIV-negative (21.0% women and 79.0% MSM) Thai subjects. The prevalence of oral HPV infection was 17.2% in HIV-positive subjects whereas only 5.3% of HIV-negative cases had HPV detected in their oral rinses (p=0.0346). Among HIV positive subjects, MSM had higher chance of having HPV infection than females (25% vs. 9.4%, p=0.0074).
  
  
  CONCLUSIONS
  HIV-positive Thai MSM and women had higher prevalence of oral HPV infection than those without HIV.
authors.affiliation: Faculty of Dentistry, Srinakharinwirot University, 114 Sukhumvit 23 Road, Wattana, Bangkok 10110, Thailand. Electronic address: piamkamonv@yahoo.com.
authors.forename: Piamkamon
authors.initials: P
authors.lastname: Vacharotayangul
authors.affiliation: Faculty of Dentistry, Srinakharinwirot University, 114 Sukhumvit 23 Road, Wattana, Bangkok 10110, Thailand.
authors.forename: Sorasun
authors.initials: S
authors.lastname: Rungsiyanont
authors.affiliation: Faculty of Dentistry, Srinakharinwirot University, 114 Sukhumvit 23 Road, Wattana, Bangkok 10110, Thailand.
authors.forename: Aroonwan
authors.initials: A
authors.lastname: Lam-Ubol
authors.affiliation: The Thai Red Cross AIDS Research Centre, 104 Ratchadamri Road, Pathumwan, Bangkok 10330, Thailand.
authors.forename: Tippawan
authors.initials: T
authors.lastname: Pankam
authors.affiliation: The Thai Red Cross AIDS Research Centre, 104 Ratchadamri Road, Pathumwan, Bangkok 10330, Thailand.
authors.forename: Piyanee
authors.initials: P
authors.lastname: Rodbamrung
authors.affiliation: Faculty of Dentistry, Prince of Songkla University, 15 Karnjanavanich Rd., Hat Yai, Songkhla 90112, Thailand.
authors.forename: Supawadee
authors.initials: S
authors.lastname: Naorungroj
authors.affiliation: The Thai Red Cross AIDS Research Centre, 104 Ratchadamri Road, Pathumwan, Bangkok 10330, Thailand; SEARCH, 104 Ratchadamri Road, Pathumwan, Bangkok 10330, Thailand.
authors.forename: Nittaya
authors.initials: N
authors.lastname: Phanuphak
mesh_terms: D000328:Adult; D005260:Female; D005838:Genotype; D015658:HIV Infections / Q000453:epidemiology; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000453:epidemiology* / Q000821:virology*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology; D015995:Prevalence; D013785:Thailand / Q000453:epidemiology; D055815:Young Adult
keywords: HIV; HPV; MSM; Oral cavity; Oropharyngeal cancer