title: Asymmetric Brønsted Acid Catalyzed Synthesis of Triarylmethanes-Construction of Communesin and Spiroindoline Scaffolds.
abstract: Aza-ortho-quinone methides allow the straightforward asymmetric synthesis of natural-product-inspired indole scaffolds possessing a quaternary stereocenter. Our approach provides access to diverse communesin and spiroindoline derivatives with high enantioselectivity under mild reaction conditions. Predictable substitution patterns are found to be the key to our regiodivergent protocols.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen, Landoltweg 1, 52074 Aachen (Germany), Fax: (+49) 241-809-2665.
authors.forename: Hsuan-Hung
authors.initials: HH
authors.lastname: Liao
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen, Landoltweg 1, 52074 Aachen (Germany), Fax: (+49) 241-809-2665.
authors.forename: Adisak
authors.initials: A
authors.lastname: Chatupheeraphat
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen, Landoltweg 1, 52074 Aachen (Germany), Fax: (+49) 241-809-2665.
authors.forename: Chien-Chi
authors.initials: CC
authors.lastname: Hsiao
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen, Landoltweg 1, 52074 Aachen (Germany), Fax: (+49) 241-809-2665.
authors.forename: Iuliana
authors.initials: I
authors.lastname: Atodiresei
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen, Landoltweg 1, 52074 Aachen (Germany), Fax: (+49) 241-809-2665. magnus.rueping@rwth-aachen.de.
authors.forename: Magnus
authors.initials: M
authors.lastname: Rueping
keywords: Michael addition; counterions; fluorine; organocatalysis; rearrangements