title: TRPV1 channel modulation by hyaluronan reduces pain.
authors.affiliation: a Instituto de Neurociencias , Universidad Miguel Hernández-CSIC , Alicante , Spain.
authors.forename: Elvira
authors.initials: E
authors.lastname: de la Peña
authors.affiliation: a Instituto de Neurociencias , Universidad Miguel Hernández-CSIC , Alicante , Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Gomis
authors.affiliation: b Instituto de Biología Molecular y Celular , Universidad Miguel Hernández , Alicante , Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Ferrer-Montiel
authors.affiliation: a Instituto de Neurociencias , Universidad Miguel Hernández-CSIC , Alicante , Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Belmonte
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000700:Analgesics / Q000494:pharmacology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002211:Capsaicin / Q000037:antagonists & inhibitors / Q000494:pharmacology; D005109:Extracellular Matrix / Q000187:drug effects / Q000378:metabolism; D057809:HEK293 Cells; D006358:Hot Temperature; D006801:Humans; D006820:Hyaluronic Acid / Q000494:pharmacology*; D007249:Inflammation; D007270:Injections, Intra-Articular; D015640:Ion Channel Gating / Q000187:drug effects; D007719:Knee Joint / Q000187:drug effects* / Q000294:innervation / Q000378:metabolism / Q000473:pathology; D009437:Neuralgia / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*; D050916:TRPV Cation Channels / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D050916:TRPV Cation Channels; C494482:TRPV1 protein, human; D006820:Hyaluronic Acid; D002211:Capsaicin
keywords: TRPV1; analgesic; arthritis; hyaluronan; nociceptive; osteoarthritis; pain; strectch-activated channels