title: Can Head and Neck Cancers Be Detected with Mean Platelet Volume?
abstract: BACKGROUND
  Mean platelet volume (MPV) is a marker which has been investigated in many cancers but data for head and neck lesions are limited. We aimed to study the MPV levels in head and neck cancers as a diagnostic marker.
  
  
  METHODS
  A total of 96 head and neck cancer patients and 31 control patients who did not meet exclusion criteria were enrolled in the study. The cancer locations, the platelet and MPV levels at the first diagnosis time were collected.
  
  
  RESULTS
  The head and neck cancer location distribution between these patients was 2 (2.1%) buccal, 9 (9.4%) tongue, 6 (6.3) lip, 1 (1%) gingiva, 1 (1%) hypopharynx, 1 (1%) ear, 58 (60.4%) larynx, 2 (2.1%) maxilla, 2 (2.1%) nasal, 1 (1%) nasopharynx, 2 (2.1%) palatal, 3 (3.1%) primary unknown, 1 (1%) retromolar, 1 (1%) thyroid, 2 (2.1%) tonsil, and 4 (4.2%) salivary gland. MPV levels were significantly different between cancer and control group (p=0.002). The cut-off point for MPV predicting head and neck cancer is >10 fL (sensitivity=55.21, specificity=87.10).
  
  
  CONCLUSIONS
  MPV level increase, a readily assessable parameter which does not bring extra costs can warn us regarding head and neck cancer risk.
authors.affiliation: Otorhinolaryngology, Medical School, Adnan Menderes University School of Medicine, Aydin, Turkey E-mail : draylineryilmaz@gmail.com.
authors.forename: Aylin
authors.initials: A
authors.lastname: Eryilmaz
authors.forename: Yesim
authors.initials: Y
authors.lastname: Basal
authors.forename: Imran Kurt
authors.initials: IK
authors.lastname: Omurlu
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006258:Head and Neck Neoplasms / Q000097:blood* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D012372:ROC Curve
chemical_list: D014408:Biomarkers, Tumor