title: Foot-and-Mouth Disease Seroprevalence in Cattle in Eritrea.
abstract: Information about seroprevalence of foot-and-mouth disease (FMD) and virus serotypes in Eritrea is unavailable, but is very important as it may guide the choice of intervention measures including vaccination to be implemented. We carried out a cross-sectional study from February to June 2011 in Eritrea with a two-stage cluster design, sampling cattle in 155 villages with the objective of determining the seroprevalence of FMD in four administrative regions of the country. We analysed cattle sera (n = 2429) for FMD virus antibodies using the non-structural ELISA (NS ELISA) and virus neutralization test (VNT). The overall seroprevalence was 26% and 30% for the NS ELISA and VNT, respectively. FMD virus serotypes O (14%) and A (11%) were the most prevalent. Gash Barka showed the highest (39%) seroprevalence both in NS ELISA and VNT compared to the other three administrative regions. Strategic FMD virus vaccination with type O and A (matching circulating strains) in combination of zoo-sanitary measures would be the best control option for Eritrea which could be started in areas where the disease is less endemic.
authors.affiliation: Central Veterinary Institute (Part of Wageningen UR), Lelystad, The Netherlands.|National Veterinary Laboratory, Ministry of Agriculture, Asmara, Eritrea.
authors.forename: T
authors.initials: T
authors.lastname: Tekleghiorghis
authors.affiliation: Central Veterinary Institute (Part of Wageningen UR), Lelystad, The Netherlands.
authors.forename: K
authors.initials: K
authors.lastname: Weerdmeester
authors.affiliation: Central Veterinary Institute (Part of Wageningen UR), Lelystad, The Netherlands.
authors.forename: F
authors.initials: F
authors.lastname: van Hemert-Kluitenberg
authors.affiliation: Central Veterinary Institute (Part of Wageningen UR), Lelystad, The Netherlands.|Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
authors.forename: R J M
authors.initials: RJM
authors.lastname: Moormann
authors.affiliation: Central Veterinary Institute (Part of Wageningen UR), Lelystad, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Dekker
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000453:epidemiology / Q000821:virology*; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D019017:Eritrea / Q000453:epidemiology; D005536:Foot-and-Mouth Disease / Q000097:blood / Q000453:epidemiology*; D029544:Foot-and-Mouth Disease Virus / Q000145:classification / Q000276:immunology; D015995:Prevalence; D016036:Seroepidemiologic Studies; D065288:Serogroup
chemical_list: D000914:Antibodies, Viral
keywords: Eritrea; administrative regions; foot-and-mouth disease virus; seroprevalence; serotypes; vaccination