title: Self-disseminating vaccines for emerging infectious diseases.
abstract: Modern human activity fueled by economic development is profoundly altering our relationship with microorganisms. This altered interaction with microbes is believed to be the major driving force behind the increased rate of emerging infectious diseases from animals. The spate of recent infectious disease outbreaks, including Ebola virus disease and Middle East respiratory syndrome, emphasize the need for development of new innovative tools to manage these emerging diseases. Disseminating vaccines are one such novel approach to potentially interrupt animal to human (zoonotic) transmission of these pathogens.
authors.affiliation: a School of Biomedical and Healthcare Sciences , Plymouth University , Plymouth , UK.
authors.forename: Aisling A
authors.initials: AA
authors.lastname: Murphy
authors.affiliation: b The Institute for Immunology and Infectious Diseases , Murdoch University , Murdoch , Western Australia , Australia.
authors.forename: Alec J
authors.initials: AJ
authors.lastname: Redwood
authors.affiliation: a School of Biomedical and Healthcare Sciences , Plymouth University , Plymouth , UK.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Jarvis
mesh_terms: D000818:Animals; D021821:Communicable Diseases, Emerging / Q000453:epidemiology* / Q000517:prevention & control* / Q000635:transmission; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D006801:Humans; D007114:Immunization / Q000379:methods*; D014612:Vaccines / Q000008:administration & dosage / Q000276:immunology* / Q000302:isolation & purification; D015047:Zoonoses / Q000453:epidemiology* / Q000517:prevention & control* / Q000635:transmission
chemical_list: D014612:Vaccines
keywords: CMV; Disseminating; Ebola; cytomegalovirus; emerging infectious disease; epidemic; transmission; vaccine; wildlife; zoonosis