title: Electrochemical Determination of Uric Acid at CdTe Quantum Dot Modified Glassy Carbon Electrodes.
abstract: Cyclic voltammetry and differential pulse voltammetry were used to investigate the electrochemical behavior of uric acid (UA) at a CdTe quantum dot (QD) modified the glassy carbon electrode (GCE). CdTe QDs, as new semiconductor nanocrystals, can greatly improve the peak current of UA. The anodic peak current of UA was linear with its concentration between 1.0×10(-6) and 4.0×10(-4) M in 0.1 M pH 5.0 phosphate buffer solution. The LOD for UA at the CdTe electrode (1.0×10(-7) M) was superior to that of the GCE. In addition, we also determined the effects of scan rate, pH, and interferences of UA for the voltammetric behavior and detection. The results indicated that modified electrode possessed excellent reproducibility and stability. Finally, a new and efficient electrochemical sensor for detecting UA was developed.
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health School of Harbin Medical University, Harbin, Heilongjiang, 150081, China.
authors.forename: Deng
authors.initials: D
authors.lastname: Pan
authors.forename: Shengzhong
authors.initials: S
authors.lastname: Rong
authors.forename: Guangteng
authors.initials: G
authors.lastname: Zhang
authors.forename: Yannan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhou
authors.forename: Fenghai
authors.initials: F
authors.lastname: Liu
authors.forename: Miaojing
authors.initials: M
authors.lastname: Li
authors.forename: Dong
authors.initials: D
authors.lastname: Chang
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Pan
mesh_terms: D002021:Buffers; D019187:Cadmium Compounds / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004566:Electrodes; D006801:Humans; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D045663:Quantum Dots / Q000737:chemistry*; D015203:Reproducibility of Results; D013691:Tellurium / Q000737:chemistry*; D014527:Uric Acid / Q000097:blood*
chemical_list: D002021:Buffers; D019187:Cadmium Compounds; D014527:Uric Acid; D002244:Carbon; D013691:Tellurium; C028337:cadmium telluride