title: Synthesis at the Speed of Codons.
abstract: The possibility that different mRNA sequences encoding identical peptides are translated dissimilarly has long been of great interest. Recent work by Yu and co-workers provides striking evidence that mRNA sequences influence the rate of protein synthesis, and lends support to the emerging idea that mRNA sequence informs protein folding.
authors.affiliation: Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
authors.forename: Kristin S
authors.initials: KS
authors.lastname: Koutmou
authors.affiliation: Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
authors.forename: Aditya
authors.initials: A
authors.lastname: Radhakrishnan
authors.affiliation: Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address: ragreen@jhmi.edu.
authors.forename: Rachel
authors.initials: R
authors.lastname: Green
mesh_terms: D000818:Animals; D003062:Codon / Q000235:genetics*; D010441:Peptide Chain Elongation, Translational; D017510:Protein Folding
chemical_list: D003062:Codon