title: [Exploring a non-inflammatory clinical breast mass: Clinical practice guidelines].
abstract: OBJECTIVE
  The aim of the study was to assess the diagnostic value of physical examination, radiologic explorations and percutaneous procedures of the breast in the exploration of a non-inflammatory palpable mass, in order to propose guidelines.
  
  
  METHODS
  A systematic literature review was conducted in the Medline and Cochrane library databases. International guidelines in French and English language were also consulted until April 30th 2015.
  
  
  RESULTS
  Physical examination of a non-inflammatory palpable breast mass is not sufficient to eliminate a breast cancer (LE2). Mammography alone has a sensitivity between 70 and 95% for the diagnosis of breast cancer (LE3). Echography alone has a sensitivity of 98 to 100% for the diagnosis of breast cancer (LE2). The core needle biopsy has a better sensitivity and specificity than the fine-needle aspiration for breast cancer diagnosis (LE2). The association of mammography and 2D echography presents excellent sensitivity and negative predictive value (close to 100 %) to exclude a breast cancer (LE3). A double evaluation using mammography and echography is recommended in the exploration of a non-inflammatory palpable breast mass (grade B).
authors.affiliation: Service de gynécologie-obstétrique, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 01, France; CESP-Inserm, U1018, équipe 7, genre, santé sexuelle et reproductive, université Paris Sud, 94276 Le Kremlin-Bicêtre, France. Electronic address: g_legendre@hotmail.com.
authors.forename: G
authors.initials: G
authors.lastname: Legendre
authors.affiliation: Service de gynécologie-obstétrique, CHU de Poitiers, 2, rue de la Milétrie, BP 577, 86021 Poitiers cedex, France.
authors.forename: N
authors.initials: N
authors.lastname: Guilhen
authors.affiliation: Service de gynécologie-obstétrique, CHU de Poitiers, 2, rue de la Milétrie, BP 577, 86021 Poitiers cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Nadeau
authors.affiliation: Service de gynécologie-obstétrique, CHU de Poitiers, 2, rue de la Milétrie, BP 577, 86021 Poitiers cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Brossard
authors.affiliation: Service de gynécologie-obstétrique, CHU de Caen, avenue de la Côte-de-Nacre, 14033 Caen cedex 09, France; Inserm U1199, unité « Biologie et thérapies innovantes des cancers localement agressifs » (BioTICLA), université de Caen Basse-Normandie, centre de lutte contre le cancer François-Baclesse, 14076 Caen cedex 05, France.
authors.forename: R
authors.initials: R
authors.lastname: Fauvet
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D017410:Practice Guidelines as Topic; D011859:Radiography; D014463:Ultrasonography
keywords: Biopsie percutanée; Clinical examination; Cytoponction; Examen clinique; Fine-needle aspiration biopsy; Mammographie; Mammography; Percutaneous biopsy; Ultrasound; Échographie