title: Understanding leukemic hematopoiesis as a complex adaptive system.
abstract: Normal and abnormal hematopoiesis is working as a complex adaptive system. From this perspective, the development and the behavior of hematopoietic cell lineages appear as a balance between normal and abnormal hematopoiesis in the setting of a functioning or malfunctioning microenvironment under the control of the immune system and the influence of hereditary and environmental events.
authors.affiliation: Xavier Thomas, Department of Hematology, Lyon-Sud Hospital, 69495 Pierre Bénite Cedex, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Thomas
keywords: Acute leukemia; Complex adaptive system; Hematopoiesis; Stem cells; Treatment