title: Prevalence of Schistosomes and Soil-Transmitted Helminths and Morbidity Associated with Schistosomiasis among Adult Population in Lake Victoria Basin, Tanzania.
abstract: The objective of this study was to carry out a community survey on schistosomiais and soil-transmitted helminth (STH) infections in order to suggest feasible and effective intervention strategies in Lake Victoria basin, Tanzania. A total of 37 communities selected from 23 districts of the 4 regions in the Lake Victoria basin of Tanzania were involved in the study. From each of the selected locality, 50 adult community members, 25 males and 25 females, were recruited for the study. Each study participant was requested to submit stool and urine specimens. From each stool specimen, duplicate Kato-Katz thick smears were prepared and microscopically examined for Schistosoma mansoni and STH eggs. Urine specimens were processed by the filtration technique and microscopically examined for Schistosoma haematobium eggs. Ultrasound examination for morbidity due to schistosomiasis was performed. Mass treatment was done using praziquantel and albendazole for schistosome and STHs infections, respectively. Out of 1,606 adults who provided stool specimens, 199 (12.4%) were positive for S. mansoni, 349 (21.7%) for hookworms, 133 (8.3%) for Ascaris lumbricoides, and 33 (2.0%) for Trichuris trichiura. Out of 1,400 participants who provided urine specimens, 25 (1.8%) were positive for S. haematobium eggs. Because of the co-endemicity of these afflictions and their impact on vulnerable population groups, the helminthiasis could be simultaneously treated with 2 drugs, praziquantel for schistosomiasis and albendazole for STHs.
authors.affiliation: National Institute of Medical Research, P.O. Box 1462, Mwanza, Tanzania.
authors.forename: Julius E
authors.initials: JE
authors.lastname: Siza
authors.affiliation: National Institute of Medical Research, P.O. Box 1462, Mwanza, Tanzania.
authors.forename: Godfrey M
authors.initials: GM
authors.lastname: Kaatano
authors.affiliation: Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.
authors.forename: Jong-Yil
authors.initials: JY
authors.lastname: Chai
authors.affiliation: Department of Parasitology and Medical Research Institute, Chungbuk National University School of Medicine, Cheongju 28644, Korea.
authors.forename: Keeseon S
authors.initials: KS
authors.lastname: Eom
authors.affiliation: Department of Parasitology, College of Medicine, Korea University, Seoul 02841, Korea.
authors.forename: Han-Jong
authors.initials: HJ
authors.lastname: Rim
authors.affiliation: Department of Environmental Medical Biology and Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul 03722, Korea.
authors.forename: Tai-Soon
authors.initials: TS
authors.lastname: Yong
authors.affiliation: Department of Microbiology and Immunology, Eulji University College of Medicine, Daejeon 35233, Korea.
authors.forename: Duk-Young
authors.initials: DY
authors.lastname: Min
authors.affiliation: Good Neighbors International, Tanzania Western Chapter, P.O. Box 367, Mwanza, Tanzania.
authors.forename: Su Young
authors.initials: SY
authors.lastname: Chang
authors.affiliation: Good Neighbors International, Tanzania Western Chapter, P.O. Box 367, Mwanza, Tanzania.
authors.forename: Yunsuk
authors.initials: Y
authors.lastname: Ko
authors.affiliation: National Institute of Medical Research, P.O. Box 1462, Mwanza, Tanzania.
authors.forename: John M
authors.initials: JM
authors.lastname: Changalucha
mesh_terms: D000328:Adult; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D005243:Feces / Q000469:parasitology; D005260:Female; D006373:Helminthiasis / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology / Q000473:pathology*; D006376:Helminths / Q000145:classification* / Q000302:isolation & purification*; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology / Q000473:pathology*; D060106:Lakes; D008297:Male; D008853:Microscopy; D011223:Praziquantel / Q000627:therapeutic use; D015995:Prevalence; D012552:Schistosomiasis / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology / Q000473:pathology*; D013636:Tanzania / Q000453:epidemiology; D014556:Urine / Q000469:parasitology
chemical_list: D000871:Anthelmintics; D011223:Praziquantel; D015766:Albendazole
keywords: Lake Victoria basin; Schistosoma haematobium; Schistosoma mansoni; Tanzania; adult population; soil-transmitted helminth (STH)