title: Molecular characterization of group A rotavirus before and after the introduction of vaccines in Brazil.
abstract: BACKGROUND
  In this study, the molecular characteristics of group A rotavirus (RVA) were compared in samples obtained before and after RVA vaccine-introduction in Brazil.
  
  
  METHODS
  Eighty samples were screened for the presence of RVA. Positive samples were molecularly analyzed.
  
  
  RESULTS
  RVA positivity was 16.9%, with a predominance of G2P[4]. Periods: pre-vaccination: predominance of IId (G1), IId (G2) lineages, and I1 and E1 genotypes; post-vaccination: predominance of Ib (G1), IIa, and IIc (G2) lineages and I2 and E2 genotypes.
  
  
  CONCLUSIONS
  Although changes in RVA-circulation pattern were observed in the post-vaccination period, it could not be attributed to vaccination process.
authors.affiliation: Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
authors.forename: Tâmera Nunes Vieira
authors.initials: TN
authors.lastname: Almeida
authors.affiliation: Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
authors.forename: Fabíola Souza
authors.initials: FS
authors.lastname: Fiaccadori
authors.affiliation: Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
authors.forename: Menira
authors.initials: M
authors.lastname: Souza
authors.affiliation: Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
authors.forename: Ana Maria Tavares
authors.initials: AM
authors.lastname: Borges
authors.affiliation: Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
authors.forename: Divina das Dôres de Paula
authors.initials: Dd
authors.lastname: Cardoso
mesh_terms: D000956:Antigens, Viral / Q000276:immunology; D001938:Brazil; D005243:Feces / Q000821:virology; D005838:Genotype; D006801:Humans; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D012401:Rotavirus / Q000235:genetics* / Q000276:immunology; D012400:Rotavirus Infections / Q000517:prevention & control / Q000821:virology*; D022243:Rotavirus Vaccines / Q000008:administration & dosage*; D014611:Vaccination
chemical_list: D000956:Antigens, Viral; D012367:RNA, Viral; D022243:Rotavirus Vaccines