title: [Cases of non-standard approach to treatment of super-refractory status epilepticus].
abstract: Authors assume that super-refractoriness is probably characterized by the specific pathophysiological mechanisms of status epilepticus development and can't be treated using standard treatment schemes. By the example of two clinical cases, we have analyzed the efficacy of complex treatment of super-refractory nonconvulsive and myoclonic status using intravenous valproate, central anesthetics (thiopental sodium, propofol), levetiracetam and cortexin. Preliminary results suggest that cortexin and levetiracetam as add-on to standard treatment may be vitally important drugs for the patients.
authors.affiliation: Evdokimov Moscow State University of Dentistry, Moscow.
authors.forename: V A
authors.initials: VA
authors.lastname: Karlov
authors.affiliation: Evdokimov Moscow State University of Dentistry, Moscow.
authors.forename: P N
authors.initials: PN
authors.lastname: Vlasov
authors.affiliation: Evdokimov Moscow State University of Dentistry, Moscow.
authors.forename: B P
authors.initials: BP
authors.lastname: Gladov
authors.affiliation: Evdokimov Moscow State University of Dentistry, Moscow.
authors.forename: E G
authors.initials: EG
authors.lastname: Kamelkova
mesh_terms: D000328:Adult; D018686:Anesthetics, Intravenous / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D002985:Clinical Protocols; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D005260:Female; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D000077287:Levetiracetam; D010455:Peptides / Q000627:therapeutic use; D010889:Piracetam / Q000031:analogs & derivatives / Q000627:therapeutic use; D015742:Propofol / Q000627:therapeutic use; D013226:Status Epilepticus / Q000188:drug therapy* / Q000503:physiopathology; D013874:Thiopental / Q000627:therapeutic use; D016896:Treatment Outcome; D014635:Valproic Acid / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D018686:Anesthetics, Intravenous; D000927:Anticonvulsants; D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; D000077287:Levetiracetam; D014635:Valproic Acid; C056590:cortexin; D013874:Thiopental; D015742:Propofol; D010889:Piracetam