title: [Comparative oncologic and functional outcomes of prostate cancer surgery with other curative treatments].
abstract: OBJECTIVE
  Review of the comparative results of different treatment strategies (surgery, radiotherapy, ultrasound, surveillance) of prostate cancer, in which the main goal is the local control and the second target is the tolerance of the side effects of those treatments.
  
  
  METHODS
  Review of literature using Medline databases selected based on scientific relevance. Clinical keys centered on the oncological and functional outcomes of comparative series between different curative treatments.
  
  
  RESULTS
  The numerous comparative series between surgery and other therapeutic modalities are essentially retrospective with significant methodological bias that is difficult to overcome in order to formulate the optimal thesis. However, there is a clear tendency toward surgery usually with young patients who have intermediate risk tumors without important comorbidity.
  
  
  CONCLUSIONS
  In the absence of randomized comparative series with significant power, the oncological and functional results of the radical prostatectomy with or without adjuvant treatment seem at least the same, in a selected population of patients, compared with the combination of radiotherapy-hormonotherapy in terms of survival, without biochemical recurrence, disease-specific survival and overall survival, for the aggressive tumors necessitating curative local treatments.
authors.affiliation: Département d'urologie-andrologie-transplantation rénale, CHU Rangueil, 1, avenue Jean-Poulhès, 31059 Toulouse cedex 9, France. Electronic address: soulie.m@chu-toulouse.fr.
authors.forename: M
authors.initials: M
authors.lastname: Soulié
authors.affiliation: Service d'urologie et de transplantation rénale et pancréatique, CHU Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France.
authors.forename: L
authors.initials: L
authors.lastname: Salomon
mesh_terms: D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000601:surgery / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Brachytherapy; Cancer de la prostate; Cryotherapy; Cryothérapie; Curiethérapie; Dysfonction érectile; Erectile dysfunction; Functional results; High-intensity focused ultrasound; Hormonal treatment; Hormonothérapie; Incontinence urinaire; Oncological outcomes; Overall survival; Prostate cancer; Prostatectomie totale; Radical prostatectomy; Radiotherapy; Radiothérapie; Résultats fonctionnels; Résultats oncologiques; Specific survival; Surveillance; Survie globale; Survie spécifique; Ultrasons focalisés; Urinary incontinence