title: [Development of Determination Method of Ipfencarbazone in Agricultural Products, Livestock Products and Seafood by LC-MS/MS].
abstract: A method for the determination of ipfencarbazone in agricultural products, livestock products and seafood by LC-MS/MS was developed. Agricultural samples were extracted with acetone. An aliquot of crude extract was partitioned with n-hexane and sat. sodium chloride solution. Clean-up was performed using GC/PSA and C18 cartridges. In the case of livestock products and seafood, samples were extracted with a mixture of acetone and n-hexane, and the organic layer was collected. After acetonitrile-hexane partitioning, the extract was cleaned up using PAS and C18 cartridges. The gradient LC separation was performed on a C18 column with acetonitrile-water containing acetic acid as a mobile phase, and MS with positive ion electrospray ionization was used for detection. The average recoveries (n=5) of ipfencarbazone from 16 kinds of agricultural products, livestock products and seafood spiked at the MRLs or at the uniform limits (0.01 ppm) were 73-101%, and the relative standard deviations were 1.3-5.1%. The limit of quantitation of the developed method was 0.01 mg/kg for ipfencarbazone.
authors.affiliation: Saitama Prefectural Institute of Public Health.
authors.forename: Koichi
authors.initials: K
authors.lastname: Imai
authors.forename: Keiko
authors.initials: K
authors.lastname: Onoue
authors.forename: Rie
authors.initials: R
authors.lastname: Ishii
authors.forename: Mariko
authors.initials: M
authors.lastname: Takano
authors.forename: Satoru
authors.initials: S
authors.lastname: Nemoto
authors.forename: Reiko
authors.initials: R
authors.lastname: Teshima
mesh_terms: D000813:Anilides / Q000032:analysis* / Q000737:chemistry; D000818:Animals; D002853:Chromatography, Liquid / Q000379:methods*; D018556:Crops, Agricultural / Q000737:chemistry*; D004531:Eggs / Q000032:analysis; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D006540:Herbicides / Q000032:analysis*; D008461:Meat Products / Q000032:analysis*; D008892:Milk / Q000737:chemistry; D017747:Seafood / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014230:Triazoles / Q000032:analysis* / Q000737:chemistry
chemical_list: D000813:Anilides; D006540:Herbicides; D014230:Triazoles; C000608242:ipfencarbazone