title: Very late scaffold thrombosis of everolimus-eluting bioresorbable scaffold following implantation in STEMI after discontinuation of dual antiplatelet therapy.
abstract: A 42-year-old male with a history of smoking and dyslipidemia was admitted due to ST-elevation myocardial infarction. Coronary angiography showed severe stenosis in proximal right coronary artery (RCA) and total occlusion in mid RCA. Absorb everolimus-eluting bioresorbable scaffolds were deployed in mid and proximal RCA. The patient was discharged with dual anti-platelet therapy. Patient was admitted 15-months later due to acute coronary syndrome with scaffold thrombosis. Both aspirin and clopidogrel had been discontinued 1 month prior to the second event because of general malaise. Therefore, either aspirin or clopidogrel should have been continued even after 1 year following stent implantation.
authors.affiliation: CVPath Institute, Gaithersburg, MD, USA.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Yahagi
authors.affiliation: CVPath Institute, Gaithersburg, MD, USA.
authors.forename: Renu
authors.initials: R
authors.lastname: Virmani
authors.affiliation: Meenakshi Hospital, Thanjavur, 613007, Tamil Nadu, India. drbkesav@gmail.com.
authors.forename: Bhoopalan
authors.initials: B
authors.lastname: Kesavamoorthy
mesh_terms: D020341:Absorbable Implants / Q000009:adverse effects*; D000328:Adult; D000077144:Clopidogrel; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000209:etiology*; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000601:surgery*; D054855:Drug-Eluting Stents; D000068338:Everolimus / Q000494:pharmacology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011183:Postoperative Complications; D011474:Prosthesis Design; D000072657:ST Elevation Myocardial Infarction / Q000175:diagnosis / Q000601:surgery*; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D054457:Tissue Scaffolds / Q000009:adverse effects*; D028761:Withholding Treatment
chemical_list: D007166:Immunosuppressive Agents; D010975:Platelet Aggregation Inhibitors; D000068338:Everolimus; D000077144:Clopidogrel; D013988:Ticlopidine
keywords: BRS; BVS; DAPT; Stent thrombosis; Very late scaffold thrombosis