title: Osseointegration of Plateau Root Form Implants: Unique Healing Pathway Leading to Haversian-Like Long-Term Morphology.
abstract: Endosteal dental implants have been utilized as anchors for dental and orthopedic rehabilitations for decades with one of the highest treatment success rates in medicine. Such success is due to the phenomenon of osseointegration where after the implant surgical placement, bone healing results into an intimate contact between bone and implant surface. While osseointegration is an established phenomenon, the route which osseointegration occurs around endosteal implants is related to various implant design factors including surgical instrumentation and implant macro, micro, and nanometer scale geometry. In an implant system where void spaces (healing chambers) are present between the implant and bone immediately after placement, its inherent bone healing pathway results in unique opportunities to accelerate the osseointegration phenomenon at the short-term and its maintenance on the long-term through a haversian-like bone morphology and mechanical properties.
authors.affiliation: Department of Biomaterials and Biomimetics, New York University, New York, NY, USA. pgcoelho@gmail.com.|Department of Periodontology and Implant Dentistry, New York University, New York, NY, USA. pgcoelho@gmail.com.|Department of Engineering, New York University Abu Dhabi, Abu Dhabi, UAE. pgcoelho@gmail.com.
authors.forename: Paulo G
authors.initials: PG
authors.lastname: Coelho
authors.affiliation: Department of Operative Dentistry and Prosthodontics, Tufts University School of Dental Medicine, Boston, MA, USA.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Suzuki
authors.affiliation: Postgraduate Program in Dentistry, UNIGRANRIO University, Duque de Caxias, RJ, Brasil.
authors.forename: Charles
authors.initials: C
authors.lastname: Marin
authors.affiliation: Postgraduate Program in Dentistry, UNIGRANRIO University, Duque de Caxias, RJ, Brasil.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Granato
authors.affiliation: Department of Dentistry, Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Luis F
authors.initials: LF
authors.lastname: Gil
authors.affiliation: Department of Biomaterials and Biomimetics, New York University, New York, NY, USA.
authors.forename: Nick
authors.initials: N
authors.lastname: Tovar
authors.affiliation: Faculty of Odontology, Department of Prosthodontics, Malmö University, Malmö, Sweden.
authors.forename: Ryo
authors.initials: R
authors.lastname: Jimbo
authors.affiliation: Department of Periodontology, University of Florida, Gainesville, FL, USA.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Neiva
authors.affiliation: Department of Prosthodontics, University of Sao Paulo - Bauru College of Dentistry, Bauru, SP, Brazil.
authors.forename: Estevam A
authors.initials: EA
authors.lastname: Bonfante
mesh_terms: D000818:Animals; D016723:Bone Remodeling / Q000502:physiology; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry; D017267:Dental Prosthesis Design; D055119:Elastic Modulus / Q000502:physiology; D006801:Humans; D016348:Osseointegration / Q000502:physiology*; D010012:Osteogenesis / Q000502:physiology; D013499:Surface Properties; D013997:Time Factors; D014945:Wound Healing / Q000502:physiology*
chemical_list: D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D003764:Dental Materials
keywords: Bone healing; Bone regeneration; Implants; Osseointegration; Plateau root form; Tissue engineering