title: Anatomical variation in bifurcation and trifurcations of sciatic nerve and its clinical implications: in selected university in Ethiopia.
abstract: BACKGROUND
  The Sciatic nerve is the widest nerve of the body. It consists of two components, namely: the tibia and the common peroneal components derived from the ventral rami of L4 to S3 spinal nerves of the lumbosacral plexus. It exits the pelvis through the greater sciatic foramen below the Piriformis muscle and descends between the greater trochanter of the femur and ischial tuberosity of the pelvis to the knee. The purpose of this study is to identify the course and variations in branching pattern of the sciatic nerve which may lead to various clinical manifestations.
  
  
  METHODS
  Twenty-eight formalin fixed cadavers comprising of 56 lower limbs are used for this study, of which six specimens were female cadavers. Dissection of gluteal region and posterior compartment of the thigh was done to expose the sciatic nerve. Variations in the sciatic nerve anatomy; their relationship to Piriformis muscle and a point of bifurcation and trifurcation were noted and recorded.
  
  
  RESULTS
  Forty-two lower limbs (75 %) showed normal anatomy of sciatic nerve. Fourteen regions (25 %) showed variations in the sciatic nerve, of which six regions (11 %) showed a variation of the sciatic nerve in relation to Piriformis muscle, three regions (5 %) showed trifurcation of the sciatic nerve and five regions (9 %) showed variation in the origin of the sural nerve.
  
  
  CONCLUSIONS
  The knowledge regarding the level of division and distribution of the sciatic nerve and its location is of great importance. The sciatic nerve is frequently involved in daily medical practice of neurology, orthopedics, rehabilitation and anesthesia. Its long course makes it vulnerable to nerve injury. Even in this era the cadaver is the best means to study anatomy. It emphasizes proper clinical implications, for the surgeons to practice efficient surgical recombination and avoid errors.
authors.affiliation: Department of Anatomy and Histology, Institute of Biomedical Sciences, College of Health Sciences, Mekelle University, Mekelle, Ethiopia. birhane.visionary27@gmail.com.
authors.forename: Birhane Alem
authors.initials: BA
authors.lastname: Berihu
authors.affiliation: Department of Physiology, Institute of Bio-Medical Sciences, College of Health Sciences, Mekelle University, Mekelle, Ethiopia. godefayy@yahoo.com.
authors.forename: Yared Godefa
authors.initials: YG
authors.lastname: Debeb
mesh_terms: D002081:Buttocks / Q000294:innervation; D002102:Cadaver; D005002:Ethiopia; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000294:innervation*; D008297:Male; D018482:Muscle, Skeletal / Q000294:innervation*; D010543:Peroneal Nerve / Q000033:anatomy & histology / Q000502:physiology; D012584:Sciatic Nerve / Q000033:anatomy & histology* / Q000502:physiology*; D013497:Sural Nerve / Q000033:anatomy & histology / Q000502:physiology; D013848:Thigh / Q000294:innervation; D013979:Tibial Nerve / Q000033:anatomy & histology / Q000502:physiology; D014495:Universities