title: [The long-term clinical efficacy of endoscopic surgery of primary sinonasal malignant neoplasms].
abstract: OBJECTIVE
  To assess the long-term clinical efficacy of endoscopic surgery of primary sinonasal malignant neoplasms and find out the potential postoperative prognostic factors.
  
  
  METHODS
  Forty-three clinical cases of primary sinonasal malignant neoplasms treated under endoscopy were analyzed retrospectively.
  
  
  RESULTS
  Fifteen patients died. The 1-year, 2-year, 3-year and 5-year survival rates were 83. 7% (36/43), 74. 4% (32/43), 69. 8% (30/43) and 65. 1% (28/43), respectively. Kaplan-Meier single-variable analysis showed that gender, T grade, TNM stage and pathological types of olfactory neuroblastoma were statistically significant prognostic factors (P< 0. 05). COX Pro-Portional hazard models showed that TNM stage was an independent prognostic factors.
  
  
  CONCLUSIONS
  Endoscopic surgery for primary sinonasal malignant neoplasms is a safe and effective minimally invasive surgical treatment, and it is an important supplement to the traditional surgery. Gender, T grade, TNM stage and pathological types of olfactory neuroblastoma might be significant prognostic factors.
authors.forename: Yudong
authors.initials: Y
authors.lastname: Ye
authors.forename: Qianhui
authors.initials: Q
authors.lastname: Qiu
authors.forename: Shuixing
authors.initials: S
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Huang
authors.forename: Jiandong
authors.initials: J
authors.lastname: Zhan
authors.forename: Mimi
authors.initials: M
authors.lastname: Xu
mesh_terms: D004724:Endoscopy; D018304:Esthesioneuroblastoma, Olfactory / Q000601:surgery*; D006801:Humans; D009296:Nasal Cavity / Q000473:pathology / Q000601:surgery; D009669:Nose Neoplasms / Q000601:surgery*; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome