title: BEHAVIOR OF ADIPOKINES AFTER A YEAR FOLLOW-UP IN THE OBESITY OUTPATIENT CLINIC FOR CHILDREN AND ADOLESCENTS.
abstract: OBJECTIVE
  demonstrate adipokines progression, along 12 months, in obese children and adolescents who attend the Obesity Outpatient Clinic for Children and Adolescents of the HCPA.
  
  
  METHODS
  children and adolescents in medical treatment for obesity were followed for 12 months, assessing anthropometry, blood pressure, waist circumference, lipid profile, fasting blood sugar and insulin, inter leukine- 6, tumor necrosis factor alpha, and adiponectin in two points in time: at inclusion and after 12 months follow-up in the Obesity Outpatient Clinic for Children and Adolescents.
  
  
  RESULTS
  27 children and adolescents were assessed with median age of 10.3 years. The mean BMI z-scores lowered during this period (p < 0.01), HDL-c increased in the period (p = 0.025). The medians of adipokines did not vary during the period: IL-6 (p = 0.470), TNF-α (p = 0.753) and adiponectin (p = 0.943). There was no correlation of IL-6 and TNF-α with central and global obesity along the 12-months follow-up. Adiponectin increased in 45% of the sample, the increase being more pronounced in females.
  
  
  CONCLUSIONS
  children and adolescents in medical treatment for obesity, after one-year follow-up, did not improve their adiponectin profile.
authors.affiliation: Nutritionist, Master in Medical Sciences: Nephrology (FAMED/UFRGS), PhD in Children and Adolescents Health, Professor in the Nutrition Course and Graduation Course in Health and Human Development of the Centro Universitário La Salle, Canoas, RS.. fernandamiraglia@terra.com.br.
authors.forename: Fernanda
authors.initials: F
authors.lastname: Miraglia
authors.affiliation: Nutritionist, Master in Children and Adolescents Health, Clinical Nutritionist at the Hospital de Clínicas de Porto Alegre, Nutrology Service, Porto Alegre, RS.. elzadmello@gmail.com.
authors.forename: Carla Rosane
authors.initials: CR
authors.lastname: de Moraes Silveira
authors.affiliation: Doctor in Epidemiology, Department of Professional Help and Guidance (DAOP) of the Nursing School of the Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS.. elzadmello@gmail.com.
authors.forename: Mariur
authors.initials: M
authors.lastname: Gomes Beghetto
authors.affiliation: PhD in Children and Adolescents Health, UFRGS. Reviewer for the Journal of Pediatric Surgery (Print), Porto Alegre, RS.. elzadmello@gmail.com.
authors.forename: Fernanda
authors.initials: F
authors.lastname: dos Santos Oliveira
authors.affiliation: PhD in Pediatrics, Nutrology Service of the HCPA and Pediatrics Department (FAMED/UFRGS), Porto Alegre, RS, Brazil.. elzadmello@gmail.com.
authors.forename: Elza Daniel
authors.initials: ED
authors.lastname: de Mello
mesh_terms: D054392:Adipokines / Q000097:blood*; D052242:Adiponectin / Q000097:blood; D000293:Adolescent; D000554:Ambulatory Care Facilities; D015992:Body Mass Index; D002648:Child; D015331:Cohort Studies; D016207:Cytokines / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009765:Obesity / Q000097:blood* / Q000628:therapy*; D055105:Waist Circumference
chemical_list: C499918:ADIPOQ protein, human; D054392:Adipokines; D052242:Adiponectin; D016207:Cytokines