title: A novel characterization of posterior keratoconus using anterior segment optical coherence tomography in an infant: a case report.
abstract: BACKGROUND
  Posterior keratoconus is a rare cause of a corneal opacity in an infant. It is characterized by thinning of the posterior cornea without ectasia of the anterior cornea. Imaging of this condition with anterior segment optical coherence tomography (AS-OCT) has not been reported in the literature.
  
  
  METHODS
  A six week old African-American male presented with a congenital corneal opacity of the right eye. He underwent an examination under anesthesia in which photography and AS-OCT were performed. AS-OCT confirmed the diagnosis of posterior keratoconus. The patient subsequently underwent an optical iridectomy for visual development.
  
  
  CONCLUSIONS
  AS-OCT is a useful tool in cases when a child presents with a corneal opacity of unknown or unclear etiology. In our patient, AS-OCT showed the classic description of central corneal thinning seen in this condition. Additionally, it revealed an associated detached Descemet membrane, a feature which has not been previously described in posterior keratoconus.
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St, Miami, FL, 33136, USA. nisha.garg@med.miami.edu.
authors.forename: Nisha
authors.initials: N
authors.lastname: Garg
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St, Miami, FL, 33136, USA. t.chang@med.miami.edu.
authors.forename: Ta C
authors.initials: TC
authors.lastname: Chang
authors.affiliation: Children's Hospital Los Angeles, 4650 Sunset Blvd., Los Angeles, CA, 90027, USA. Bibiana.Reiser@med.usc.edu.|University of Southern California Eye Institute, 1450 San Pablo Street, Los Angeles, CA, 90033-4682, USA. Bibiana.Reiser@med.usc.edu.
authors.forename: Bibiana Jin
authors.initials: BJ
authors.lastname: Reiser
authors.affiliation: Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St, Miami, FL, 33136, USA. kcavuoto@med.miami.edu.
authors.forename: Kara M
authors.initials: KM
authors.lastname: Cavuoto
mesh_terms: D000869:Anterior Eye Segment / Q000473:pathology*; D003318:Corneal Opacity / Q000151:congenital / Q000175:diagnosis*; D063171:Corneal Pachymetry; D005865:Gestational Age; D006801:Humans; D007223:Infant; D032801:Iridectomy; D007640:Keratoconus / Q000151:congenital / Q000175:diagnosis*; D008297:Male; D041623:Tomography, Optical Coherence / Q000379:methods*