title: [Formation of paroxysmal brain activity in the liquidators of the consequences of the Chernobyl nuclear disaster].
abstract: OBJECTIVE
  To investigate the effect of ionizing radiation on the formation of paroxysmal brain activity (PBA) in the liquidators of the consequences of the Chernobyl nuclear disaster in view of their age on the date of exposure to radiation.
  
  
  METHODS
  EEG examinations were performed in 105 liquidators of the consequences of the nuclear disaster (LCND) and 90 people without radiation anamnesis (control group).
  
  
  CONCLUSIONS
  It has been determined that the formation of paroxysmal brain activity in LCND occurs 3.5 times more frequent (p<0.001) and 15-17 years earlier (p<0.001) than in the control group and mainly during the first 10 years after the exposure to radiation. The history of the exposure to ionizing radiation is associated with the increased risk of the development of convulsive PBA as focal seizures by 5.5 times (p<0.001), interictal epileptiform discharges (IED) in EEG by 3.3 times (p<0.001). Radiation effect on LCND under 30 years old increases (as compared to the control group) the risk of the formation of elevated paroxysmal brain activity by 19 times (p<0.001), convulsive epileptic seizures by 33.3 times (p<0.001), interictal epileptiform discharges in EEG by 12 times (p<0.001), asymptomatic focal epileptoid nidus in EEG by 9.3 times (p<0.001). Stimulating effect of ionizing radiation on the development of PBA related to the age on the date of exposure to radiation was found.
authors.affiliation: Altai Regional Hospital for Veterans of Wars, Barnaul.
authors.forename: I V
authors.initials: IV
authors.lastname: Podsonnaya
authors.affiliation: Altai State Medical University, Barnaul.
authors.forename: G I
authors.initials: GI
authors.lastname: Shumacher
authors.affiliation: Altai State Medical University, Barnaul.
authors.forename: G G
authors.initials: GG
authors.lastname: Efremushkin
authors.affiliation: Altai Regional Hospital for Veterans of Wars, Barnaul.
authors.forename: E D
authors.initials: ED
authors.lastname: Gelobetskaya
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001921:Brain / Q000503:physiopathology* / Q000528:radiation effects*; D047852:Chernobyl Nuclear Accident; D004569:Electroencephalography; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D011832:Radiation Injuries / Q000209:etiology* / Q000503:physiopathology; D011839:Radiation, Ionizing; D012640:Seizures / Q000209:etiology* / Q000503:physiopathology; D055815:Young Adult