title: A working model for the type III secretion mechanism in Chlamydia.
abstract: It has been appreciated for almost 20 years that members of the Chlamydiales possess a virulence-associated type III secretion mechanism. Given the obligate intracellular nature of these bacteria, defining exactly how type III secretion functions to promote pathogenesis has been challenging. We present a working model herein that is based on current evidence.
authors.affiliation: Department of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
authors.forename: Joshua C
authors.initials: JC
authors.lastname: Ferrell
authors.affiliation: Department of Microbiology, Immunology & Molecular Genetics, University of Kentucky College of Medicine, Lexington, KY 40536, USA. Electronic address: Ken.fields@uky.edu.
authors.forename: Kenneth A
authors.initials: KA
authors.lastname: Fields
mesh_terms: D002689:Chlamydia / Q000737:chemistry / Q000378:metabolism / Q000472:pathogenicity*; D008954:Models, Biological; D008958:Models, Molecular; D000069296:Type III Secretion Systems / Q000737:chemistry / Q000378:metabolism*; D037521:Virulence Factors / Q000378:metabolism*
chemical_list: D000069296:Type III Secretion Systems; D037521:Virulence Factors
keywords: Effector; Pathogenesis; Secretion