title: Optimization of a Cemented Femoral Prosthesis Considering Bone Remodeling.
abstract: The study presents a numerical methodology for minimizing the bone loss in human femur submitted to total hip replacement (THR) procedure with focus on cemented femoral stem. Three-dimensional computational models were used to describe the femoral bone behavior. An optimization procedure using the genetic algorithm (GA) method was applied in order to minimize the bone loss, considering the geometry and the material of the prosthesis as well as the design of the stem. Internal and external bone remodeling were analyzed numerically. The numerical method proposed here showed that the bone mass loss could be reduced by 24%, changing the design parameters.
authors.forename: Leandro Luis
authors.initials: LL
authors.lastname: Corso
authors.forename: Leandro de Freitas
authors.initials: Lde F
authors.lastname: Spinelli
authors.forename: Fernando
authors.initials: F
authors.lastname: Schnaid
authors.forename: Crisley Dossin
authors.initials: CD
authors.lastname: Zanrosso
authors.forename: Rogério José
authors.initials: RJ
authors.lastname: Marczak
mesh_terms: D000465:Algorithms; D019644:Arthroplasty, Replacement, Hip; D001843:Bone Cements; D016723:Bone Remodeling; D005269:Femur / Q000000981:diagnostic imaging / Q000502:physiology* / Q000601:surgery; D000066506:Heuristics; D006801:Humans; D011474:Prosthesis Design; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D001843:Bone Cements