title: Effects of Osmotic Changes on Measuring Relative Blood Volume: Comparison of Three Hemodialysis Devices.
abstract: Recording the relative blood volume is a standard feature of modern dialysis devices. Three different measurement systems are incorporated in currently available dialysis machines. The Gambro-Hospal group and Nikkiso feature blood volume monitors based on different optical methods. The Fresenius Medical Care machines perform blood volume monitoring with an ultrasonic method. On grounds of clinical evidence suggesting a malfunction of the optical methods in the presence of sodium changes, we compared these three systems. Under the tested conditions, both optical systems show opposite and nonplausible courses of blood volume changes. The ultrasonic system seems to be less susceptible to osmotic changes.
authors.affiliation: From the *Department of Nephrology, Charite Universitätsmedizin Berlin, Berlin, Germany; and †KfH Kidney Center Berlin-Köpenick, Berlin, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Kron
authors.forename: Reinhard
authors.initials: R
authors.lastname: Wenkel
authors.forename: Til
authors.initials: T
authors.lastname: Leimbach
authors.forename: Sabine
authors.initials: S
authors.lastname: Aign
authors.forename: Joachim
authors.initials: J
authors.lastname: Kron
mesh_terms: D001810:Blood Volume / Q000502:physiology*; D001811:Blood Volume Determination / Q000295:instrumentation*; D006801:Humans; D009995:Osmosis; D006435:Renal Dialysis / Q000295:instrumentation*