title: [The efficacy of cytoflavin in the treatment of burnout syndrome].
abstract: OBJECTIVE
  To evaluate the efficacy of cytoflavin in the treatment of patients with burnout syndrome.
  
  
  METHODS
  Authors performed clinical, psychological and neurophysiological examinations of 60 patients, aged 34-43 years. Results of pharmacological therapy with cytoflavin (30 patients) or ethylmethylhydroxypyridine succinate (30 patients) were compared. Control examination was conducted immediately after treatment and then after 30 days to assess the stability of the resulting effect.
  
  
  CONCLUSIONS
  The higher efficacy of cytoflavin (improvement in 80% of cases) as compared to ethylmethylhydroxypyridine succinate (improvement in 70% of cases) was identified. After cytoflavin treatment, the improvement was more persistent. These clinical results are confirmed by the results of psychological and neurophysiological research.
authors.affiliation: Bekhterev Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: L S
authors.initials: LS
authors.lastname: Chutko
authors.affiliation: Bekhterev Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: S Yu
authors.initials: SY
authors.lastname: Surushkina
authors.affiliation: Bekhterev Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: E A
authors.initials: EA
authors.lastname: Yakovenko
authors.affiliation: Bekhterev Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: A V
authors.initials: AV
authors.lastname: Rozhkova
authors.affiliation: Bekhterev Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: T I
authors.initials: TI
authors.lastname: Anisimova
authors.affiliation: Bekhterev Institute of Human Brain, Russian Academy of Sciences, St. Petersburg.
authors.forename: Yu L
authors.initials: YL
authors.lastname: Bondarchuk
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D002055:Burnout, Professional / Q000188:drug therapy*; D004338:Drug Combinations; D005260:Female; D005486:Flavin Mononucleotide / Q000627:therapeutic use*; D006801:Humans; D007290:Inosine Diphosphate / Q000627:therapeutic use*; D008297:Male; D009536:Niacinamide / Q000627:therapeutic use*; D013386:Succinates / Q000627:therapeutic use*; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D004338:Drug Combinations; D013386:Succinates; C507879:cytoflavin; D009536:Niacinamide; D005486:Flavin Mononucleotide; D007290:Inosine Diphosphate