title: Evaluation of N-terminal pro-B-type natriuretic peptide and high-sensitivity C-reactive protein relationship with features of metabolic syndrome in high-risk subgroups for cardiovascular disease.
abstract: OBJECTIVE
  This study evaluating N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) and high-sensitivity C-reactive protein (hs-CRP) relationship with features of the metabolic syndrome (MS) in high risk subgroups for cardiovascular disease (CVD) in Trinidad.
  
  
  METHODS
  The sample population consisted of 160 subjects, 78 of whom were African and 82 East Indian attending medical outpatient clinics of regional health authority hospitals of Trinidad.
  
  
  RESULTS
  Systolic blood pressure, triglycerides, glucose and insulin as well as NT-pro-BNP were elevated among the East Indian sub-population, with only systolic blood pressure being significantly elevated among the African sub-population. NT-pro-BNP and hs-CRP demonstrated significant correlations with respect to the majority of independent risk factors inclusive of Adult Treatment Panel III and American Association of Clinical Endocrinologists defined criteria for MS. NT-pro-BNP demonstrated stronger association among the East Indian sub-population as compared to that of the African sub-population.
  
  
  CONCLUSIONS
  Our study showed that the East Indian subgroup was more at risk for CVD as evidenced by the fulfillment of the criteria for diagnosis of MS and therefore NT-pro-BNP and hs-CRP can be deemed a suitable marker for MS.
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Bijoor Shivananda
authors.initials: BS
authors.lastname: Nayak
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Avinas
authors.initials: A
authors.lastname: Jagessar
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Zaryd
authors.initials: Z
authors.lastname: Mohammed
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Jarryd
authors.initials: J
authors.lastname: Rampersad
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Solange
authors.initials: S
authors.lastname: Ramkissoon
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Shivonne
authors.initials: S
authors.lastname: Biswah
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Amisha
authors.initials: A
authors.lastname: Mohammed
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Aneela
authors.initials: A
authors.lastname: Maraj
authors.affiliation: Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
authors.forename: Christina
authors.initials: C
authors.lastname: Rampersad
keywords: Cardiovascular disease; N-terminal pro-B-type natriuretic peptide; high-sensitivity C-reactive protein; metabolic syndrome