title: Seasons of Risk: Anticipated Behavior on Vacation and Interest in Episodic Antiretroviral Pre-exposure Prophylaxis (PrEP) Among a Large National Sample of U.S. Men Who have Sex with Men (MSM).
abstract: The current analysis evaluates interest in and acceptability of daily PrEP during short episodes of anticipated increased risk (i.e. Epi-PrEP). In 2013, U.S. members of an internet-based MSM sexual networking site were invited to complete a survey about HIV prevention practices in the context of vacationing. 7305 MSM responded to the survey. Of respondents who had vacationed in the past year, 25.6 % reported condomless anal sex (CAS) with new male sex partners while vacationing. Most (92.6 %) respondents agreed that having to use PrEP every day was a barrier to PrEP use and 74.3 % indicated they would take PrEP if they knew it would be helpful for short periods of anticipated increased risk. MSM who reported increased CAS while on vacation in the past year were more likely to indicate that they would take PrEP if it were helpful when used for short periods than respondents who did not (aOR = 2.02, 95 % CI 1.59-2.56, p < 0.001). Studies designed to evaluate uptake, adherence, and protective benefit of short PrEP courses are warranted.
authors.affiliation: The Fenway Institute, Fenway Health, 8th floor, 1340 Boylston Street, Boston, MA, 02115, USA.
authors.forename: Steven A
authors.initials: SA
authors.lastname: Elsesser
authors.affiliation: The Fenway Institute, Fenway Health, 8th floor, 1340 Boylston Street, Boston, MA, 02115, USA.|Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
authors.forename: Catherine E
authors.initials: CE
authors.lastname: Oldenburg
authors.affiliation: The Fenway Institute, Fenway Health, 8th floor, 1340 Boylston Street, Boston, MA, 02115, USA.|Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
authors.forename: Katie B
authors.initials: KB
authors.lastname: Biello
authors.affiliation: The Fenway Institute, Fenway Health, 8th floor, 1340 Boylston Street, Boston, MA, 02115, USA.|Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.|Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Mimiaga
authors.affiliation: The Fenway Institute, Fenway Health, 8th floor, 1340 Boylston Street, Boston, MA, 02115, USA.|Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.|Department of Medicine, Harvard Medical School, Boston, MA, USA.
authors.forename: Steven A
authors.initials: SA
authors.lastname: Safren
authors.affiliation: Department of Behavioral and Community Health Sciences, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: James E
authors.initials: JE
authors.lastname: Egan
authors.affiliation: OLB Research Institute, Online Buddies, Inc., Cambridge, USA.
authors.forename: David S
authors.initials: DS
authors.lastname: Novak
authors.affiliation: The Fenway Institute, Fenway Health, 8th floor, 1340 Boylston Street, Boston, MA, 02115, USA.|Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
authors.forename: Douglas S
authors.initials: DS
authors.lastname: Krakower
authors.affiliation: Department of Behavioral and Social Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: Ron
authors.initials: R
authors.lastname: Stall
authors.affiliation: The Fenway Institute, Fenway Health, 8th floor, 1340 Boylston Street, Boston, MA, 02115, USA. kmayer@fenwayhealth.org.|Department of Medicine, Harvard Medical School, Boston, MA, USA. kmayer@fenwayhealth.org.|Department of Global Health and Population, Harvard School of Public Health, Boston, MA, USA. kmayer@fenwayhealth.org.
authors.forename: Kenneth H
authors.initials: KH
authors.lastname: Mayer
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage*; D015658:HIV Infections / Q000517:prevention & control* / Q000523:psychology; D018451:Homosexuality, Male / Q000523:psychology / Q000706:statistics & numerical data*; D006801:Humans; D020407:Internet; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data; D065129:Pre-Exposure Prophylaxis / Q000379:methods*; D012309:Risk-Taking; D021841:Safe Sex; D012621:Seasons; D012725:Sexual Behavior / Q000706:statistics & numerical data; D012747:Sexual Partners; D011795:Surveys and Questionnaires; D014481:United States; D047568:Unsafe Sex / Q000523:psychology; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents
keywords: Epi-PrEP; Episodic PrEP; HIV; MSM; PrEP