title: The effectiveness of misoprostol or dinoprostone in neonatal outcome after labour induction in post-term nulliparas.
abstract: OBJECTIVE
  The object of this study was to investigate the efficacy of vaginal administration of misoprostol versus dinoprostone in neonatal outcome.
  
  
  METHODS
  The first Group A included 77 pregnant women, who requested pregnancy termination one week after labour term and received vaginally misoprostol 50 µg, while the other 69 pregnant women in Group B were vaginally administrated three mg dinoprostone. According to the authors' protocol this procedure was repeated after six hours for a maximum of two times.
  
  
  RESULTS
  The labour duration was longer in Group B (p = 0.000), while the APGAR score was better in Group A (p = 0.015). In Group A the labour modus was as follows: 86.9% normal vaginal labour, 3.8% vacuum extraction, and 9.3% cesarean section, while in Group B it was 82.83% normal vaginal labour, 3.07% vacuum extraction, and 14.1% cesarean section.
  
  
  CONCLUSIONS
  Misoprostol has advantages according to neonatal outcome compared to administration of dinoprostone.
authors.forename: M
authors.initials: M
authors.lastname: Soilemetzidis
authors.forename: P
authors.initials: P
authors.lastname: Pinidis
authors.forename: N
authors.initials: N
authors.lastname: Tsagias
authors.forename: A
authors.initials: A
authors.lastname: Ammari
authors.forename: A
authors.initials: A
authors.lastname: Liberis
authors.forename: V
authors.initials: V
authors.lastname: Liberis
authors.forename: G
authors.initials: G
authors.lastname: Galazios
authors.forename: P
authors.initials: P
authors.lastname: Tsikouras
mesh_terms: D000282:Administration, Intravaginal; D000293:Adolescent; D000328:Adult; D001034:Apgar Score; D002585:Cesarean Section; D015232:Dinoprostone / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced / Q000379:methods*; D007743:Labor, Obstetric; D016595:Misoprostol / Q000008:administration & dosage*; D010120:Oxytocics / Q000008:administration & dosage*; D010298:Parity; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D014620:Vacuum Extraction, Obstetrical; D055815:Young Adult
chemical_list: D010120:Oxytocics; D016595:Misoprostol; D015232:Dinoprostone