title: The First Case of Pulmonary Alveolar Proteinosis With Small Cell Lung Carcinoma.
abstract: Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disease characterized by alveolar accumulation of surfactant lipids and proteins. It is usually autoimmune and secondary to hematologic malignancy or infection. To date, only 5 case reports of PAP associated with lung cancers, including 2 cases of squamous cell carcinoma and 3 cases of adenocarcinoma, have been published. To the best of our knowledge, no case of PAP with small cell lung carcinoma has been reported thus far. We herein report the first case of PAP associated with small cell lung carcinoma.
authors.affiliation: Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
authors.forename: Tsubasa
authors.initials: T
authors.lastname: Hiraki
authors.affiliation: Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Goto
authors.affiliation: Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
authors.forename: Ikumi
authors.initials: I
authors.lastname: Kitazono
authors.affiliation: Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tasaki
authors.affiliation: Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
authors.forename: Michiyo
authors.initials: M
authors.lastname: Higashi
authors.affiliation: Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan kh1966@m2.kufm.kagoshima-u.ac.jp.
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Hatanaka
authors.affiliation: Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
authors.forename: Akihide
authors.initials: A
authors.lastname: Tanimoto
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011649:Pulmonary Alveolar Proteinosis / Q000150:complications*; D055752:Small Cell Lung Carcinoma / Q000150:complications*
chemical_list: D014408:Biomarkers, Tumor
keywords: lung cancer; pulmonary alveolar proteinosis; small cell carcinoma