title: Ni-catalyzed reductive addition of alkyl halides to isocyanides.
abstract: This paper highlights Ni-catalyzed reductive trapping of secondary and tertiary alkyl radicals with both electron-rich and electron-deficient aryl isocyanides using zinc as the terminal reductant, affording 6-alkylated phenanthridine in good yields. The employment of carbene ligands necessitates the alkyl radical process, and represents the first utility in the Ni-catalyzed reductive conditions for the generation of unactivated alkyl radicals from the halide precursors.
authors.affiliation: Shanghai University, Department of Chemistry, 99 Shang-Da Road, Shanghai 200444, China. Hegui_gong@shu.edu.cn tongwq@staff.shu.edu.cn.
authors.forename: Bo
authors.initials: B
authors.lastname: Wang
authors.forename: Yijing
authors.initials: Y
authors.lastname: Dai
authors.forename: Weiqi
authors.initials: W
authors.lastname: Tong
authors.forename: Hegui
authors.initials: H
authors.lastname: Gong