title: The Complexity of Pain Management in Patients with Erythromelalgia.
abstract: A 15-year-old girl diagnosed with erythromelalgia was admitted to the hospital with severe pain in her feet associated with burning, pruritus, erythema, and swelling. She had not responded to conventional management and received some relief only from cold bath immersions, which resulted in chronic blistering and multiple episodes of superinfection. After a successful trial of spinal cord stimulation, she had a permanent implantation procedure. The spinal cord stimulator relieved her pain and improved function but not the sensation of burning pain. However, this pain resolved after she started daily mexiletine. This case demonstrates that erythromelalgia sometimes can be managed successfully with a combination of pharmacologic and interventional procedures.
authors.affiliation: From the *Department of Anesthesiology, and †Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, California.
authors.forename: Neha
authors.initials: N
authors.lastname: Patel
authors.forename: Emily
authors.initials: E
authors.lastname: Chen
authors.forename: Giovanni
authors.initials: G
authors.lastname: Cucchiaro
mesh_terms: D000293:Adolescent; D003131:Combined Modality Therapy; D004599:Electric Stimulation Therapy; D004916:Erythromelalgia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008801:Mexiletine / Q000627:therapeutic use*; D059408:Pain Management; D061567:Voltage-Gated Sodium Channel Blockers / Q000627:therapeutic use*
chemical_list: D061567:Voltage-Gated Sodium Channel Blockers; D008801:Mexiletine