title: Out of body, out of space: Impaired reference frame processing in eating disorders.
abstract: A distorted body representation is a core symptom in eating disorders (EDs), though its mechanism is unclear. Allocentric lock theory, emphasising the role of reference frame processing in body image, suggests that ED patients may be (b)locked to an (allocentric) representation of their own body stored in long-term memory (e.g., my body is fat) that is not updated (modified) by the (real-time egocentric) perception-driven experience of the physical body. Employing a well-validated virtual reality-based procedure, relative to healthy controls, ED patients showed deficits in the ability to refer to and update a long-term stored (allocentric) representation with (egocentric) perceptual-driven inputs.
authors.affiliation: Applied Technology for Neuro-Psychology Lab, IRCCS Istituto Auxologico Italiano, Via Magnasco 2, 20149 Milan, Italy. Electronic address: s.serino@auxologico.it.
authors.forename: Silvia
authors.initials: S
authors.lastname: Serino
authors.affiliation: Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy; Department of Surgery and Interdisciplinary Medicine, University of Milano-Bicocca, Milan, Italy.
authors.forename: Antonios
authors.initials: A
authors.lastname: Dakanalis
authors.affiliation: Centre for Integrated Research-Area of Diagnostic Imaging, University Campus Bio-Medico, Rome, Italy.
authors.forename: Santino
authors.initials: S
authors.lastname: Gaudio
authors.affiliation: Division of Psychiatry, Faculty of Brain Sciences, University College of London, London, UK.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Carrà
authors.affiliation: Applied Technology for Neuro-Psychology Lab, IRCCS Istituto Auxologico Italiano, Via Magnasco 2, 20149 Milan, Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Cipresso
authors.affiliation: Department of Surgery and Interdisciplinary Medicine, University of Milano-Bicocca, Milan, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Clerici
authors.affiliation: Applied Technology for Neuro-Psychology Lab, IRCCS Istituto Auxologico Italiano, Via Magnasco 2, 20149 Milan, Italy; Department of Psychology, Catholic University of the Sacred Heart, Milan, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Riva
mesh_terms: D000293:Adolescent; D000328:Adult; D001828:Body Image / Q000523:psychology*; D003198:Computer Simulation; D001068:Feeding and Eating Disorders / Q000175:diagnosis* / Q000523:psychology*; D005260:Female; D006801:Humans; D057567:Memory, Long-Term / Q000502:physiology; D010775:Photic Stimulation / Q000379:methods; D013028:Space Perception; D055815:Young Adult
keywords: Body image; Eating disorders; Spatial reference frame