title: Lactate as predictor of mortality in polytrauma.
abstract: BACKGROUND
  The lactate is a product of anaerobic metabolism; it can be used as a marker on demand and availability of oxygen. Changes in lactate levels can be effectively used as a marker in resuscitation maneuvers, even in patients with stable vital signs.
  
  
  OBJECTIVE
  To verify the lactate clearance as a predictor of mortality in trauma patients, in need of intensive care.
  
  
  METHODS
  A total of 851 patients were admitted in ICU, in which 146 were victims of multiple trauma; due to the exclusion criteria, were included 117.
  
  
  RESULTS
  Patients were 87% male, mean age 32.4 years, motorcycle drivers, Glasgow coma scale between 3-8, affected by cranial trauma, followed by abdominal trauma. Was verified mortality up to 48 h and global mortality, that did not show statistical relationship between lactate clearance and mortality (p=0.928).
  
  
  CONCLUSIONS
  There is no correlation between admission lactate or lactate clearance and mortality in patients treated with multiple trauma.
authors.affiliation: Hospital Regional Homero de Miranda Gomes, Secretaria de Estado da Saúde, São José, SC, Brazil.
authors.forename: Andréia Diane
authors.initials: AD
authors.lastname: Freitas
authors.affiliation: Hospital Regional Homero de Miranda Gomes, Secretaria de Estado da Saúde, São José, SC, Brazil.
authors.forename: Orli
authors.initials: O
authors.lastname: Franzon
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000097:blood*; D008297:Male; D009104:Multiple Trauma / Q000097:blood* / Q000401:mortality*; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D019344:Lactic Acid