title: The Effect of Plant Proteins Derived from Cereals and Legumes on Heme Iron Absorption.
abstract: The aim of this study is to determine the effect of proteins from cereals and legumes on heme iron (Fe) absorption. The absorption of heme Fe without its native globin was measured. Thirty adult females participated in two experimental studies (15 per study). Study I focused on the effects of cereal proteins (zein, gliadin and glutelin) and study II on the effects of legume proteins (soy, pea and lentil) on heme Fe absorption. When heme was given alone (as a control), study I and II yielded 6.2% and 11.0% heme absorption (p > 0.05). In study I, heme Fe absorption was 7.2%, 7.5% and 5.9% when zein, gliadin and glutelin were added, respectively. From this, it was concluded that cereal proteins did not affect heme Fe absorption. In study II, heme Fe absorption was 7.3%, 8.1% and 9.1% with the addition of soy, pea and lentil proteins, respectively. Only soy proteins decreased heme Fe absorption (p < 0.05). These results suggest that with the exception of soy proteins, which decreased absorption, proteins derived from cereals and legumes do not affect heme Fe absorption.
authors.affiliation: Department of Food Science and Technology, University of California, Davis. 1 Shields Avenue, University of California, Davis, CA 95616, USA. vweinborn@ucdavis.edu.
authors.forename: Valerie
authors.initials: V
authors.lastname: Weinborn
authors.affiliation: Micronutrients Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Avda. El Líbano 5524, Casilla 13811, Santiago, Chile. fpizarro@inta.uchile.cl.
authors.forename: Fernando
authors.initials: F
authors.lastname: Pizarro
authors.affiliation: Micronutrients Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Avda. El Líbano 5524, Casilla 13811, Santiago, Chile. molivare@inta.uchile.cl.
authors.forename: Manuel
authors.initials: M
authors.lastname: Olivares
authors.affiliation: United States Department of Agriculture, Western Human Nutrition Research Center, University of California, 430 W. Health Sciences Drive, Davis, CA 95616, USA. abrito@ucdavis.edu.
authors.forename: Alex
authors.initials: A
authors.lastname: Brito
authors.affiliation: Micronutrients Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Avda. El Líbano 5524, Casilla 13811, Santiago, Chile. marredon@inta.uchile.cl.
authors.forename: Miguel
authors.initials: M
authors.lastname: Arredondo
authors.affiliation: Micronutrients Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Avda. El Líbano 5524, Casilla 13811, Santiago, Chile. seb.flores@postgrad.otago.ac.nz.
authors.forename: Sebastián
authors.initials: S
authors.lastname: Flores
authors.affiliation: Faculty of Veterinary and Animal Sciences, University of Chile (FAVET), Santa Rosa 11.735, La Pintana, Casilla 2, La Granja, Santiago, Chile. cvalenzuelav@u.uchile.cl.
authors.forename: Carolina
authors.initials: C
authors.lastname: Valenzuela
mesh_terms: D000328:Adult; D001682:Biological Availability; D004032:Diet; D004044:Dietary Proteins / Q000494:pharmacology*; D002523:Edible Grain / Q000737:chemistry*; D007887:Fabaceae / Q000737:chemistry*; D005260:Female; D005903:Gliadin / Q000494:pharmacology; D005983:Glutens / Q000494:pharmacology; D006418:Heme / Q000378:metabolism*; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects*; D007501:Iron / Q000493:pharmacokinetics*; D019266:Iron, Dietary / Q000493:pharmacokinetics; D027806:Lens Plant / Q000737:chemistry; D018532:Pisum sativum / Q000737:chemistry; D010940:Plant Proteins / Q000494:pharmacology*; D030262:Soybean Proteins / Q000494:pharmacology; D013025:Glycine max / Q000737:chemistry; D015028:Zein / Q000494:pharmacology
chemical_list: D004044:Dietary Proteins; D019266:Iron, Dietary; D010940:Plant Proteins; D030262:Soybean Proteins; D006418:Heme; D005983:Glutens; D005903:Gliadin; D015028:Zein; D007501:Iron
keywords: heme iron; human; iron absorption; plant protein