title: A randomised controlled trial comparing highly cross-linked and contemporary annealed polyethylene after a minimal eight-year follow-up in total hip arthroplasty using cemented acetabular components.
abstract: Most published randomised controlled trials which compare the rates of wear of conventional and cross-linked (XL) polyethylene (PE) in total hip arthroplasty (THA) have described their use with a cementless acetabular component. We conducted a prospective randomised study to assess the rates of penetration of two distinct types of PE in otherwise identical cemented all-PE acetabular components. A total of 100 consecutive patients for THA were randomised to receive an acetabular component which had been either highly XL then remelted or moderately XL then annealed. After a minimum of eight years follow-up, 38 hips in the XL group and 30 hips in the annealed group had complete data (mean follow-up of 9.1 years (7.6 to 10.7) and 8.7 years (7.2 to 10.2), respectively). In the XL group, the steady state rate of penetration from one year onwards was -0.0002 mm/year (sd 0.108): in the annealed group it was 0.1382 mm/year (sd 0.129) (Mann-Whitney U test, p < 0.001). No complication specific to either material was recorded. These results show that the yearly linear rate of femoral head penetration can be significantly reduced by using a highly XLPE cemented acetabular component.
authors.affiliation: Université Paris Descartes, 27 rue du Faubourg Saint-Jacques, 75679 Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Langlois
authors.affiliation: Université Paris Descartes, 27 rue du Faubourg Saint-Jacques, 75679 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Atlan
authors.affiliation: Université Paris Descartes, 27 rue du Faubourg Saint-Jacques, 75679 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Scemama
authors.affiliation: Université Paris Descartes, 27 rue du Faubourg Saint-Jacques, 75679 Paris, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Courpied
authors.affiliation: Université Paris Descartes, 27 rue du Faubourg Saint-Jacques, 75679 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Hamadouche
mesh_terms: D000077:Acetabulum / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D001843:Bone Cements; D002484:Cementation; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000601:surgery; D020959:Polyethylene / Q000737:chemistry*; D011095:Polyethylenes; D011474:Prosthesis Design; D011475:Prosthesis Failure / Q000209:etiology; D055815:Young Adult
chemical_list: D001843:Bone Cements; D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; D020959:Polyethylene
keywords: cemented cup; highly cross-linked polyethylene; total hip arthroplasty