title: [Treatment of postoperative cystoid macular edema (Irvine-Gass syndrome) with dexamethasone 0.7 mg intravitreal implant].
abstract: OBJECTIVE
  To evaluate the efficacy of dexamethasone 0.7 mg intravitreal implant in patients with postoperative cystoid macular edema.
  
  
  METHODS
  Fourteen patients' charts with postoperative cystoid macular edema were retrospectively reviewed. The main outcome measures were best-corrected visual acuity (BCVA) and mean central retinal thickness (CRT).
  
  
  RESULTS
  Patients' mean age was 72.1 years old. Five patients were diabetic. All patients had previously been treated with non-steroidal anti-inflammatory drops. Four patients had received a previous treatment with intravitreal ranibizumab. The mean follow-up period was 8.7 months. Mean BCVA before intravitreal dexamethasone was 0.72 logMAR. After injection, it improved to 0.50 at month 1, was 0.47 at month 3, and 0.60 logMAR at month 12. The pre-injection mean CRT was 598 μm. It improved to 286 μm at month 1, 338 μm at month 3, and was 441 μm at month 12. Eight patients received 2 intravitreal injections of dexamethasone. Five patients presented with elevated intraocular pressure during follow-up, which was treated with drops.
  
  
  CONCLUSIONS
  Intravitreal dexamethasone injection improved visual acuity and macular thickness at month 1 and month 3 in patients with postoperative cystoid macular edema. A second injection was necessary after a mean period of 5 months.
authors.affiliation: Hôpital Pasteur 2, 30, avenue de la Voie-Romaine, 06000 Nice, France.
authors.forename: C
authors.initials: C
authors.lastname: Landré
authors.affiliation: Cabinet Nice-Retina, 5, rue Eugène-Emmanuel, 06000 Nice, France.
authors.forename: A
authors.initials: A
authors.lastname: Zourdani
authors.affiliation: Hôpital Pasteur 2, 30, avenue de la Voie-Romaine, 06000 Nice, France.
authors.forename: P
authors.initials: P
authors.lastname: Gastaud
authors.affiliation: Hôpital Pasteur 2, 30, avenue de la Voie-Romaine, 06000 Nice, France. Electronic address: baillif.s@chu-nice.fr.
authors.forename: S
authors.initials: S
authors.lastname: Baillif
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002387:Cataract Extraction; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D003930:Diabetic Retinopathy / Q000188:drug therapy; D004341:Drug Evaluation; D004343:Drug Implants; D006801:Humans; D058449:Intravitreal Injections; D008269:Macular Edema / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D009798:Ocular Hypertension / Q000139:chemically induced; D011183:Postoperative Complications / Q000188:drug therapy*; D000069579:Ranibizumab / Q000627:therapeutic use; D012008:Recurrence; D012074:Remission Induction; D012163:Retinal Detachment / Q000601:surgery; D012189:Retrospective Studies; D016896:Treatment Outcome; D014221:Triamcinolone / Q000627:therapeutic use; D014792:Visual Acuity; D014821:Vitrectomy
chemical_list: D000893:Anti-Inflammatory Agents; D004343:Drug Implants; D014221:Triamcinolone; D003907:Dexamethasone; D000069579:Ranibizumab
keywords: Cataract surgery; Chirurgie de la cataracte; Implant intravitréen de déxamethasone; Intravitreal dexamethasone implant; Irvine-Gass syndrome; Postoperative cystoid macular edema; Syndrome d’Irvine-Gass; Œdème maculaire postopératoire