title: [RESEARCH PROGRESS OF STRATEGIES TO AUGMENT TENDON-TO-BONE HEALING].
abstract: OBJECTIVE
  To summarize the application status and progress of the strategies to augment tendon-to-bone healing.
  
  
  METHODS
  The present researches focused on augmentation of tendon-to-bone healing were extensively reviewed.
  
  
  RESULTS
  The present strategies to augment healing of tendon-to-bone by enhancing the location environment, and increasing the cell numbers and relative growth factor. The mainly strategies include using calcium phosphate materials, biocompatible scaffolds and glue, growth factors, cell matrix, platelet-rich plasma, and periosteum. Although periosteum have been used in clinical and got some possitive effects, the others still not be used in clinical and needs further studies.
  
  
  CONCLUSIONS
  There are many strategies to enhance the ability of tendon-to-bone healing, which got some positive results, but results of studies were varied. Thus, further fundamental research and clinical studies are required to achieve the best effects.
authors.forename: Chenghao
authors.initials: C
authors.lastname: Zhang
authors.forename: Qi
authors.initials: Q
authors.lastname: Li
authors.forename: Xin
authors.initials: X
authors.lastname: Tang
authors.forename: Jian
authors.initials: J
authors.lastname: Li
mesh_terms: D001672:Biocompatible Materials / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D002130:Calcium Phosphates; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D019637:Orthopedic Procedures; D010521:Periosteum; D053657:Platelet-Rich Plasma; D019651:Plastic Surgery Procedures / Q000379:methods* / Q000639:trends; D013708:Tendon Injuries / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy; D013710:Tendons / Q000637:transplantation*; D014182:Transplantation, Autologous; D014945:Wound Healing / Q000502:physiology*
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D036341:Intercellular Signaling Peptides and Proteins; C020243:calcium phosphate