title: Interventions for Hirsutism.
abstract: OBJECTIVE
  What medical therapies are associated with greatest efficacy and fewest adverse events for treating hirsutism?
  
  
  CONCLUSIONS
  Oral contraceptive pills (OCPs) have been associated with improvement for mild hirsutism, as has flutamide (250 mg) twice daily and spironolactone for more severe cases. Finasteride and gonadotropin-releasing analogues are associated with inconsistent results and metformin is not associated with benefit.
authors.affiliation: Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands.
authors.forename: Esther J
authors.initials: EJ
authors.lastname: van Zuuren
authors.affiliation: Bahrain Branch of Cochrane, Awali, Bahrain.
authors.forename: Zbys
authors.initials: Z
authors.lastname: Fedorowicz
mesh_terms: D058891:5-alpha Reductase Inhibitors / Q000627:therapeutic use*; D000726:Androgen Antagonists / Q000627:therapeutic use*; D003271:Contraceptive Agents, Female / Q000627:therapeutic use*; D005260:Female; D006628:Hirsutism / Q000188:drug therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*
chemical_list: D058891:5-alpha Reductase Inhibitors; D000726:Androgen Antagonists; D003271:Contraceptive Agents, Female; D007004:Hypoglycemic Agents