title: Trigeminal neuropathic pain as a complication of anterior temporal lobectomy: report of 2 cases.
abstract: Cranial nerve (CN) deficits following anterior temporal lobectomy (ATL) are an uncommon but well-recognized complication. The usual CNs implicated in post-ATL complications include the oculomotor, trochlear, and facial nerves. To the authors' knowledge, injury to the trigeminal nerve leading to neuropathic pain has not been previously described in the literature. This paper presents 2 cases of trigeminal neuropathic pain following temporal lobe resections for pharmacoresistant epilepsy. The possible pathophysiological mechanisms are discussed and the microsurgical anatomy of surgically relevant structures is reviewed.
authors.affiliation: Schulich School of Medicine and Dentistry and Faculty of Science; and.
authors.forename: Impreet
authors.initials: I
authors.lastname: Gill
authors.affiliation: Division of Neurosurgery, Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Parrent
authors.affiliation: Division of Neurosurgery, Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
authors.forename: David A
authors.initials: DA
authors.lastname: Steven
mesh_terms: D000588:Amines / Q000627:therapeutic use; D000700:Analgesics / Q000627:therapeutic use; D038481:Anterior Temporal Lobectomy / Q000009:adverse effects*; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use; D000069279:Drug Resistant Epilepsy / Q000601:surgery; D004569:Electroencephalography; D000077206:Gabapentin; D006801:Humans; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000209:etiology*; D010149:Postoperative Pain / Q000628:therapy*; D016896:Treatment Outcome; D014277:Trigeminal Neuralgia / Q000209:etiology*; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use
chemical_list: D000588:Amines; D000700:Analgesics; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin
keywords: ATL = anterior temporal lobectomy; CN = cranial nerve; EEG = electroencephalography; anterior temporal lobectomy; complications; epilepsy; pain; trigeminal nerve