title: Retrobulbar pigmented peripheral nerve sheath tumor in a dog.
abstract: A 1-year-old male castrated Pug was referred for unilateral exophthalmos unresponsive to oral antibiotic and anti-inflammatory therapy. Clinical findings included exophthalmos of the left eye with lateral strabismus, resistance to retropulsion, and an elevated nictitans. Hematologic and biochemical analyses were within normal limits. Findings following computed tomography (CT) of the head included an expansile retrobulbar soft tissue mass with bony lysis extending into the left nasal cavity and nasopharynx. Ultrasound-guided fine-needle aspirates and biopsy samples obtained via rhinoscopy were nondiagnostic. Palliative exenteration was elected; the patient was euthanized 13 weeks following exenteration due to development of neurologic signs and perceived poor quality of life. The histopathologic diagnosis was a malignant pigmented peripheral nerve sheath tumor.
authors.affiliation: College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27607, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Curto
authors.affiliation: Port City Veterinary Referral Hospital, Portsmouth, NH, 03801, USA.
authors.forename: Alison B
authors.initials: AB
authors.lastname: Clode
authors.affiliation: College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27607, USA.
authors.forename: Jessica
authors.initials: J
authors.lastname: Durrant
authors.affiliation: Southern New Hampshire Veterinary Referral Hospital, Manchester, NH, 03103, USA.
authors.forename: Keith W
authors.identifier: http://orcid.org/0000-0002-4742-7488
authors.initials: KW
authors.lastname: Montgomery
authors.affiliation: College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27607, USA. brian_gilger@ncsu.edu.
authors.forename: Brian C
authors.initials: BC
authors.lastname: Gilger
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005094:Exophthalmos; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000473:pathology / Q000662:veterinary*; D009915:Orbit; D011788:Quality of Life; D014057:Tomography, X-Ray Computed
keywords: exophthalmos; peripheral nerve sheath tumor; pigmented; pug; retrobulbar; sarcoma