title: Upper gastrointestinal bleed in a post menopausal woman due to combination of high first dose aspirin and clopidogrel prescribed for acute coronary syndrome.
abstract: Combination of aspirin, clopidogrel and enoxaparin remains the standard treatment for acute coronary syndrome (ACS) but is known to increase the incidence of upper gastrointestinal bleed (UGIB). We hereby report an unusual case of gastrointestinal bleed (GIB) as it resulted inspite of proton pump inhibitor (PPI) prophylaxis within the second day of treatment in a post-menopausal woman (PMW) with high first dose of aspirin clopidogrel dual combination in a patient of ACS.
authors.affiliation: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors.forename: Vishal R
authors.initials: VR
authors.lastname: Tandon
authors.affiliation: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors.forename: Rubeena
authors.initials: R
authors.lastname: Maqbool
authors.affiliation: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors.forename: Iram
authors.initials: I
authors.lastname: Kahkashan
authors.affiliation: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors.forename: Vijay
authors.initials: V
authors.lastname: Khajuria
authors.affiliation: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors.forename: Zahid
authors.initials: Z
authors.lastname: Gillani
keywords: Acute coronary syndrome; aspirin; clopidogrel; enoxaparin; gastrointestinal bleed