title: Successful treatment of a cat with primary hypoadrenocorticism and severe hyponatremia with desoxycorticosterone pivalate (DOCP).
abstract: A 6-year-old, castrated male Siamese cat was diagnosed with primary hypoadrenocorticism, confirmed by an adrenocorticotopic hormone (ACTH) stimulation test documenting both hypocortisolism and hypoaldosteronism. The cat was successfully treated using a combination of prednisolone and desoxycorticosterone pivalate (DOCP). This case demonstrates that DOCP can be used successfully as mineralocorticoid supplementation in cats with hypoadrenocorticism and may have a longer therapeutic duration than that in dogs.
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Woolcock
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Ward
mesh_terms: D000309:Adrenal Insufficiency / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D003900:Desoxycorticosterone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D007010:Hyponatremia / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D008901:Mineralocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D008901:Mineralocorticoids; C019323:deoxycortone pivalate; D003900:Desoxycorticosterone; D011239:Prednisolone