title: Erythema Dyschromicum Perstans: Response to Topical Tacrolimus.
abstract: BACKGROUND
  Erythema dyschromicum perstans, a rare dermatosis of obscure etiopathogenesis and significant cosmetic morbidity, have no satisfactory treatment.
  
  
  METHODS
  Two patients with having characteristic asymptomatic and slowly progressive, slate-grey macular lesions with distinct red borders involving the face, neck, upper trunk and limbs were diagnosed clinicopathologically as erythema dyschromicum perstans. Both were treated successfully with topical tacrolimus 0.1% ointment.
  
  
  CONCLUSIONS
  Overall, response to several therapeutic modalities including clofazimine and dapsone therapy is said to vary from complete failure to variable or inconsistent. Topical tarolimus provides an effective and safe alternative therapeutic option in erythema dyschromicum perstans.
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Kangra, Tanda, Himachal Pradesh, India.
authors.forename: Vikram K
authors.initials: VK
authors.lastname: Mahajan
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Kangra, Tanda, Himachal Pradesh, India.
authors.forename: Pushpinder S
authors.initials: PS
authors.lastname: Chauhan
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Kangra, Tanda, Himachal Pradesh, India.
authors.forename: Karaninder S
authors.initials: KS
authors.lastname: Mehta
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Kangra, Tanda, Himachal Pradesh, India.
authors.forename: Anju Lath
authors.initials: AL
authors.lastname: Sharma
keywords: Ashy dermatosis; clofazimine; dapsone; lichen planus pigmentosus; lichenoid dermatitis; post-inflammatory hyperpigmentation