title: The effectiveness of a program of physical activity and diet to modify cardiovascular risk factors in patients with severe mental illness after 3-month follow-up: CAPiCOR randomized clinical trial.
abstract: BACKGROUND
  The aim of this randomized clinical trial follow-up at three months was to evaluate the effectiveness of an educational intervention with a focus on diet and physical activity (PA) to change the amount of PA, body mass index (BMI) and the waist circumference (WC) in patients with severe mental illness.
  
  
  METHODS
  We recruited 332 outpatients with severe mental disorders undergoing treatment with antipsychotic medication from Mental Healthcare Centers of Barcelona. They were randomly assigned to an intervention or a control group. The patients in the intervention group participated in a group PA and diet educational program. The blinded measurements at 0 and 3 months were: the level of PA (IPAQ questionnaire), BMI, WC, blood pressure, dietary habits (PREDIMED questionnaire), quality of life (SF-36 questionnaire) and laboratory parameters (cholesterol, triglycerides, glucose).
  
  
  RESULTS
  The average age was 46.7 years and 55% were males. Schizophrenia had been diagnosed in 67.1% of them. At 3 months, the average weekly walking METs rose significantly in the IG 266.05 METs (95%CI: 16.86 to 515.25; P=0.036). The total MET average also rose although not significantly: 191.38 METs (95%CI: 1.38 to 381.38; P=0.086). However, the BMI decreased significantly more in the CG, by 0.26kg/m(2) (95%CI: 0.02 to 0.51; P=0.038), than in the IG. There were no significant differences in the WC.
  
  
  CONCLUSIONS
  The short-term results suggest that the intervention increases the level of PA, but does not improve physical or laboratory parameters.
  
  
  BACKGROUND
  Clinicaltrials.gov NCT01729650 (effectiveness of a physical activity and diet program in patients with psychotic disorder [CAPiCOR]).
authors.affiliation: EAP Besòs, Institut Català de la Salut (ICS), C/Alfons el Magnànim 57, 08019 Barcelona, Spain. Electronic address: rosermasa@gmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Masa-Font
authors.affiliation: Unitat Docent de Medicina Familiar i Comunitària, C/Sardenya 375, 08025 Barcelona, Spain.
authors.forename: M I
authors.initials: MI
authors.lastname: Fernández-San-Martín
authors.affiliation: Centre Institut de Neuropsiquiatria i Addiccions (INAD), Parc de Salut Mar Hospital del Mar, Passeig Marítím, 25-29, 08003 Barcelona, Spain.
authors.forename: L M
authors.initials: LM
authors.lastname: Martín López
authors.affiliation: Centre Salut Mental Ciutat Vella, Parc Sanitari Sant Joan de Déu, C/Via Laietana 19, 08003 Barcelona, Spain.
authors.forename: A M
authors.initials: AM
authors.lastname: Alba Muñoz
authors.affiliation: Centre Salut Mental Martí i Juliá (INAD), C/President Lluís Companys 8, 08921 Santa Coloma de Gramenet, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Oller Canet
authors.affiliation: CUAP Casernes (ICS), C/Fernando Pessoa 47-51, 08030 Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Martín Royo
authors.affiliation: Centre Salut Mental Sant Martí Nord (INAD), Pl Infància, s/n, 08020 Barcelona, Spain.
authors.forename: L
authors.initials: L
authors.lastname: San Emeterio Echevarría
authors.affiliation: Àmbit d'Atenció Primària Barcelona Ciutat, Unitat d'Avaluació, Sistemes d'Informació i Qualitat, C/Numància 23, Barcelona, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Olona Tabueña
authors.affiliation: Centre Salut Mental Sant Martí Nord (INAD), Pl Infància, s/n, 08020 Barcelona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Ibarra Jato
authors.affiliation: EAP Sant Martí (ICS), C/Fluvià 211, 08020 Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Barroso García
authors.affiliation: EAP Raval Sud (ICS), Av/Drassanes 17-21, 08001 Barcelona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: González Tejón
authors.affiliation: EAP Doctor Vilaseca (Can Mariner), C/Sant Carles 79, 08921 Santa Coloma de Gramenet, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Tajada Vitales
authors.affiliation: Centre Salut Mental Sant Martí Sud (INAD), Passeig Marítim 25-29, 08003 Barcelona, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Díaz Mújica
authors.affiliation: EAP Poblenou (ICS), C/Lope de Vega 138, 08005 Barcelona, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Viñas Cabrera
authors.affiliation: Centre Salut Mental Sant Martí Sud (INAD), Passeig Marítim 25-29, 08003 Barcelona, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Sanchís Catalán
authors.affiliation: Centre Salut Mental Sant Martí Nord (INAD), Pl Infància, s/n, 08020 Barcelona, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Salvador Barbarroja
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000150:complications / Q000523:psychology / Q000628:therapy; D002784:Cholesterol / Q000097:blood; D004035:Diet Therapy / Q000379:methods*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D011618:Psychotic Disorders / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
chemical_list: D014150:Antipsychotic Agents; D014280:Triglycerides; D002784:Cholesterol
keywords: Bipolar disorder; Cardiovascular risk factors; Diet; Physical activity; Quality of life; Schizophrenia