title: [Analysis of Optical Coherence Tomography Based on Monte Carlo Simulation Model].
abstract: A Monte Carlo model for optical coherence tomography of human skin is proposed. The new model includes importance sampling technique which is designed to suit for the multi-layer human skin, new rules for back scattered photon classification are correspondingly proposed. Based on the new simulation model, we analyzed the focusing of Gaussian beam through skin and the maximum detecting depth of optical coherence tomography. The experimental results show that there exists focus distortion when beam propagates in skin, including focus shift and diffusion. Object lens with greater NA will lower the maximum detecting depth of optical coherence tomography.
authors.forename: Liuping
authors.initials: L
authors.lastname: Lu
authors.forename: Ping
authors.initials: P
authors.lastname: Zhou
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.forename: Shijing
authors.initials: S
authors.lastname: Xue
mesh_terms: D006801:Humans; D008962:Models, Theoretical; D009010:Monte Carlo Method; D017785:Photons; D012867:Skin; D041623:Tomography, Optical Coherence