title: EFFECTS OF OATS ON LIPID PROFILE, INSULIN RESISTANCE AND WEIGHT LOSS.
abstract: BACKGROUND
  cardiovascular diseases are the main cause of morbidity worldwide. Such prevalence justifies the importance of functional foods that promote cardiovascular health, like -glucan present in oats, with potential hypocholesterolemic and hypoglycemic effects.
  
  
  OBJECTIVE
  to evaluate the effects of an intervention with oats in blood glucose levels, HOMA-IR index, lipid profile, weight and Body Mass Index (BMI) of adult users of a health service in the interior of Rio Grande do Sul, Brazil.
  
  
  METHODS
  longitudinal study, case-control type with before and after experiment, conducted with individuals that are 22-60 years old, users of a health service. The individuals were distributed in Control (usual diet) and Case (usual diet + 40 g oats/day) groups. There was performed, at the beginning of the study and after eight weeks of monitoring, measuring of height and weight, calculation of BMI (kg/m²), blood collection for measurement of fasting glucose, insulin, total cholesterol, triglycerides and HDL cholesterol; and there were calculated the LDL cholesterol and HOMA-IR index. The data was expressed as mean ± standard deviation and percentages. The Kolmogorov-Smirnov test, Student t test, Mann-Whitney and Wilcoxon tests were applied. A significance level of 5% was adopted (p < 0.05).
  
  
  RESULTS
  the sample consisted of 82 subjects, divided into cases (n = 38) and controls (n = 44), mean age 40.07 ± 10.49 years old, 58.5% were women. Comparing the results of all measured parameters at baseline and after eight weeks of monitoring, the Control group did not achieve a significant reduction in any parameter, showing a significant increase in blood glucose and HOMA- IR (p < 0.05). The Intervention group had a significant reduction of all anthropometric and biochemical parameters analyzed (p < 0.001).
  
  
  CONCLUSIONS
  the findings demonstrate the beneficial effects of oats to cardiovascular health through significantly improving of the lipid and glycemic profiles, being a potential adjuvant in the prevention and treatment of metabolic disorders.
authors.affiliation: Centro de Ciências Biológicas e da Saúde, Centro Universitário UNIVATES.. simonedb@ufcspa.edu.br.
authors.forename: Jessica
authors.initials: J
authors.lastname: Schuster
authors.affiliation: Centro de Ciências Biológicas e da Saúde, Centro Universitário UNIVATES.. simonedb@ufcspa.edu.br.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Benincá
authors.affiliation: Centro de Ciências Biológicas e da Saúde, Centro Universitário UNIVATES.. simonedb@ufcspa.edu.br.
authors.forename: Renata
authors.initials: R
authors.lastname: Vitorazzi
authors.affiliation: Centro de Ciências Biológicas e da Saúde, Centro Universitário UNIVATES. Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Brazil.. simonedb@ufcspa.edu.br.
authors.forename: Simone
authors.initials: S
authors.lastname: Morelo Dal Bosco
mesh_terms: D000328:Adult; D000368:Aged; D018554:Avena; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D016022:Case-Control Studies; D004032:Diet; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015431:Weight Loss
chemical_list: D001786:Blood Glucose; D008055:Lipids