title: Cariogenic Potential of Inhaled Antiasthmatic Drugs.
abstract: BACKGROUND
  The organism of children with asthma is exposed to the effects of the disease but also the drugs for its treatment. Antiasthmatic drugs have different modes that promote the caries formation which varies according to their basic pharmacological composition. Namely, these drugs have a relatively low pH (5.5), can contain sweeteners such as lactose monohydrate in order to improve the drug taste or both. Frequent consumption of these inhalers in combination with reduced secretion of saliva increases the risk of caries.
  
  
  METHODS
  The study sample consisted of 200 patients, age from 7-14 years, divided into two groups: control group (n1 = 100) consisted of healthy children and the experimental group consisted of children suffering from asthma (n2 = 100). In both groups of respondents are determined the DMFT index, plaque index value and hygienic-dietary habits using the questionnaire. The subjects in the control group had significantly higher DMFT index than subjects in the experimental group (p = 0.004). It is determined that there are no significant differences in the values of plaque index (p>0.05).
  
  
  CONCLUSIONS
  The effect of different diseases or medications from their treatment, diet and fermentable carbohydrates in the etiology of dental caries cannot be observed outside the living conditions of subjects, their social epidemiologic status, age, habits, oral hygiene, fluoride use, etc.
authors.affiliation: Pediatric Clinic, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.
authors.forename: Amela
authors.initials: A
authors.lastname: Brigic
authors.affiliation: Pediatric Clinic, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.
authors.forename: Sedin
authors.initials: S
authors.lastname: Kobaslija
authors.affiliation: Pediatric Clinic, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.
authors.forename: Amila
authors.initials: A
authors.lastname: Zukanovic
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D016022:Case-Control Studies; D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000139:chemically induced*; D003774:Dental Plaque Index; D005260:Female; D006801:Humans; D008297:Male; D009910:Oral Hygiene; D011795:Surveys and Questionnaires
chemical_list: D018927:Anti-Asthmatic Agents
keywords: asthma; caries; inhalers