title: A Rhodamine-Benzimidazole Based Chemosensor for Fe(3+) and its Application in Living Cells.
abstract: A rhodamine-benzimidazole based chemosensor was designed and prepared for Fe(3+) via opening of the spiro-ring to give fluorescent and colored species. L exhibited high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Fe(3+) in aqueous solution with comparatively wide pH range (5.8-7.4). The detection limit of this newly developed probe was shown to be up to 2.74 μM. The reversibility establishes the potential of both probes as chemosensors for Fe(3+) detection. Fluorescence imaging experiments of Fe(3+) in living MGC803 cells demonstrated its value of practical applications in biological systems.
authors.affiliation: School of Chemistry and Chemical Engineering, Xuchang University, Xuchang, 461000, China.
authors.forename: Gongchun
authors.initials: G
authors.lastname: Li
authors.affiliation: Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450052, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Tang
authors.affiliation: Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450052, China.
authors.forename: Peigang
authors.initials: P
authors.lastname: Ding
authors.affiliation: Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450052, China. yeyong03@tsinghua.org.cn.
authors.forename: Yong
authors.initials: Y
authors.lastname: Ye
mesh_terms: D001562:Benzimidazoles / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival; D005290:Ferric Compounds / Q000032:analysis*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D001562:Benzimidazoles; D005290:Ferric Compounds; D005456:Fluorescent Dyes; D012235:Rhodamines; C031000:benzimidazole
keywords: Fe3+; Fluorescence; Rhodamine