title: Large eccrine angiomatous hamartoma: a novel clinical presentation of disease.
abstract: BACKGROUND
  Eccrine angiomatous hamartoma is a rare benign cutaneous malformation with a diverse clinical appearance, therefore likely to be misdiagnosed and underreported.
  
  
  METHODS
  A 44-year-old man presented with a congenital erythematous hyperhidrotic plaque on the left upper back measuring 18 x 25 cm. No pain or tenderness nor hypertrichosis were observed. Histopathology was consistent with the mucinous variant of eccrine angiomatous hamartoma. Intralesional injection of botulinum toxin type A greatly reduced localized sweating, improving patient quality of life.
  
  
  CONCLUSIONS
  This article describes a novel clinical presentation of eccrine angiomatous hamartoma: large, erythematous, and slightly indurated plaque localized on the upper back. It emphasizes the role of histopathology in the diagnostic process and botulinum toxin as a viable treatment option.
authors.affiliation: Department of Dermatology and Venerology, Aarhus University Hospital, University of Aarhus, 8000 Aarhus, Denmark;
authors.forename: Uffe
authors.initials: U
authors.lastname: Nygaard
authors.affiliation: Institute of Pathology, Aarhus University Hospital, University of Aarhus, 8000 Aarhus, Denmark.
authors.forename: Søren
authors.initials: S
authors.lastname: Dalager
authors.affiliation: Institute of Pathology, Aarhus University Hospital, University of Aarhus, 8000 Aarhus, Denmark.
authors.forename: Eva
authors.initials: E
authors.lastname: Spaun
authors.affiliation: Department of Dermatology and Venerology, Aarhus University Hospital, University of Aarhus, 8000 Aarhus, Denmark;
authors.forename: Lene
authors.initials: L
authors.lastname: Hedelund
keywords: botulinum toxin; eccrine angiomatous hamartoma; eccrine naevus