title: Synthetic Biology Open Language (SBOL) Version 2.0.0.
abstract: Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.0 of SBOL, introducing a standardized format for the electronic exchange of information on the structural and functional aspects of biological designs. The standard has been designed to support the explicit and unambiguous description of biological designs by means of a well defined data model. The standard also includes rules and best practices on how to use this data model and populate it with relevant design details. The publication of this specification is intended to make these capabilities more widely accessible to potential developers and users in the synthetic biology community and beyond.
authors.forename: Bryan
authors.initials: B
authors.lastname: Bartley
authors.forename: Jacob
authors.initials: J
authors.lastname: Beal
authors.forename: Kevin
authors.initials: K
authors.lastname: Clancy
authors.forename: Goksel
authors.initials: G
authors.lastname: Misirli
authors.forename: Nicholas
authors.initials: N
authors.lastname: Roehner
authors.forename: Ernst
authors.initials: E
authors.lastname: Oberortner
authors.forename: Matthew
authors.initials: M
authors.lastname: Pocock
authors.forename: Michael
authors.initials: M
authors.lastname: Bissell
authors.forename: Curtis
authors.initials: C
authors.lastname: Madsen
authors.forename: Tramy
authors.initials: T
authors.lastname: Nguyen
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.forename: John H
authors.initials: JH
authors.lastname: Gennari
authors.forename: Chris
authors.initials: C
authors.lastname: Myers
authors.forename: Anil
authors.initials: A
authors.lastname: Wipat
authors.forename: Herbert
authors.initials: H
authors.lastname: Sauro
mesh_terms: D000818:Animals; D064229:Biological Ontologies; D003196:Computer Graphics / Q000592:standards*; D066264:Datasets as Topic / Q000592:standards; D004282:Documentation / Q000592:standards; D006801:Humans; D016247:Information Storage and Retrieval / Q000592:standards; D038622:Internationality; D008954:Models, Biological; D011381:Programming Languages; D020543:Proteome / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D058615:Synthetic Biology / Q000592:standards*
chemical_list: D020543:Proteome