title: [Progress in study of selective ERβ ligands].
abstract: Estrogen receptors (ERs) are members of nuclear receptors and related to several diseases such as cancer, inflammation and osteoporosis. ERs have two forms, ERα and ERβ, which have different functions and organism distributions. Compounds selectively targeting ERβ can regulate important physiological functions and avoid the side effects caused by targeting ERα. Therefore, selective ERβ ligands have received considerable research interest in recent years. In this article, different kinds of selective ERβ ligands were summarized and their structure-activity relationships were also analyzed.
authors.forename: Jin-ya
authors.initials: JY
authors.lastname: Cai
authors.forename: Jun-hao
authors.initials: JH
authors.lastname: Li
authors.forename: Shi-hui
authors.initials: SH
authors.lastname: Ding
authors.forename: Juan
authors.initials: J
authors.lastname: Zhang
authors.forename: Gui-xia
authors.initials: GX
authors.lastname: Liu
authors.forename: Wei-hua
authors.initials: WH
authors.lastname: Li
authors.forename: Yun
authors.initials: Y
authors.lastname: Tang
mesh_terms: D047629:Estrogen Receptor beta / Q000737:chemistry*; D006801:Humans; D008024:Ligands; D013329:Structure-Activity Relationship
chemical_list: D047629:Estrogen Receptor beta; D008024:Ligands