title: Electrochemical Biosensor Based on Nanoporous Au/CoO Core-Shell Material with Synergistic Catalysis.
abstract: An ultrathin CoO layer is deposited on the skeleton surfaces of a nanoporous gold (NPG) film by using atomic layer deposition, creating a flexible electrode. Detailed characterization demonstrates the superior performance of the flexible NPG/CoO hybrids for electrochemical catalysis. The NPG/CoO hybrid not only achieves high catalytic activity for glucose oxidation and H2O2 reduction, but also exhibits a linear dependence of the electrical signal on the concentration of glucose and H2O2 molecules in the electrolyte. Meanwhile, the sensitivity for H2O2 reduction can be as high as 62.5 μA mm(-1)  cm(-2) with linear dependence on the concentration in the range of 0.1-92.9 mm. The high sensitivity is proposed to result from the synergistic effect of Au and CoO at the interfaces, and the high conductivity of the gold skeleton with a large surface area. The superior electrochemical performance of this hybrid electrode is promising for future potential applications in various transitional-metal-oxide-based electrochemical electrodes.
authors.affiliation: School of Physics, Huazhong University of Science and Technology, 1037, Luoyu Road, Hongshan District, Wuhan, 430074, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Zhang
authors.affiliation: School of Mechanical Science and Engineering, Huazhong University of Science and Technology, 1037, Luoyu Road, Hongshan District, Wuhan, 430074, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Huang
authors.affiliation: School of Physics, Huazhong University of Science and Technology, 1037, Luoyu Road, Hongshan District, Wuhan, 430074, China. lhqian@hust.edu.cn.
authors.forename: Lihua
authors.initials: L
authors.lastname: Qian
authors.affiliation: School of Physics, Huazhong University of Science and Technology, 1037, Luoyu Road, Hongshan District, Wuhan, 430074, China.
authors.forename: Songliu
authors.initials: S
authors.lastname: Yuan
authors.affiliation: School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037, Luoyu Road, Hongshan District, Wuhan, 430074, China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Wang
authors.affiliation: School of Mechanical Science and Engineering, Huazhong University of Science and Technology, 1037, Luoyu Road, Hongshan District, Wuhan, 430074, China. rongchen@mail.hust.edu.cn.
authors.forename: Rong
authors.initials: R
authors.lastname: Chen
mesh_terms: D015374:Biosensing Techniques; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D055664:Electrochemical Techniques; D004566:Electrodes; D005947:Glucose / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry*; D016062:Porosity
chemical_list: D010087:Oxides; D003035:Cobalt; D006046:Gold; D006861:Hydrogen Peroxide; D005947:Glucose; C060728:cobalt oxide
keywords: atomic layer deposition; biosensors; cobalt monoxide; electrochemical catalysis; nanoporous gold