title: Selective extraction and determination of fluoroquinolones in bovine milk samples with montmorillonite magnetic molecularly imprinted polymers and capillary electrophoresis.
abstract: A sensitive and selective method for separating fluoroquinolones (FQs) from bovine milk samples was successfully developed using montmorillonite magnetic molecularly imprinted polymers (MMMIPs) as adsorbents. MMMIPs were prepared using montmorillonite as carrier, fleroxacin (FLE) as template molecule, and Fe3O4 magnetite as magnetic component. MMMIPs possessed high adsorption capacity of 46.3 mg g(-1) for FLE. A rapid and convenient magnetic solid-phase extraction procedure coupled with capillary electrophoresis was established with MMMIPs as adsorbents for simultaneous and selective extraction of four FQs in bovine milk samples. Limits of detection ranged between 12.9 and 18.8 μg L(-1), and the RSDs were between 1.8% and 8.6%. The proposed method was successfully applied to spike bovine milk samples with recoveries of 92.7%-108.6%.
authors.affiliation: School of Chemistry & Chemical Engineering, Zhaoqing University, Zhaoqing, 526061, China. hwwangcn@hotmail.com.
authors.forename: Hongwu
authors.initials: H
authors.lastname: Wang
authors.affiliation: School of Chemistry & Chemical Engineering, Zhaoqing University, Zhaoqing, 526061, China.
authors.forename: Yanqing
authors.initials: Y
authors.lastname: Liu
authors.affiliation: School of Chemistry & Chemical Engineering, Zhaoqing University, Zhaoqing, 526061, China. weishlmary@126.com.
authors.forename: Shoulian
authors.initials: S
authors.lastname: Wei
authors.affiliation: School of Chemistry & Chemical Engineering, Zhaoqing University, Zhaoqing, 526061, China.
authors.forename: Su
authors.initials: S
authors.lastname: Yao
authors.affiliation: Department of Chemistry, East China Jiaotong University, Nanchang, 330013, China.
authors.forename: Jiali
authors.initials: J
authors.lastname: Zhang
authors.affiliation: School of Chemistry & Chemical Engineering, Zhaoqing University, Zhaoqing, 526061, China.
authors.forename: Huichang
authors.initials: H
authors.lastname: Huang
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification*; D002417:Cattle; D004350:Drug Residues / Q000032:analysis / Q000302:isolation & purification*; D019075:Electrophoresis, Capillary / Q000379:methods*; D024841:Fluoroquinolones / Q000032:analysis / Q000302:isolation & purification*; D005506:Food Contamination / Q000032:analysis; D008280:Magnetics; D008892:Milk / Q000737:chemistry*; D054802:Molecular Imprinting; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D011108:Polymers
keywords: Bovine milk; Capillary electrophoresis; Fluoroquinolone; Magnetic solid-phase extraction; Montmorillonite magnetic molecularly imprinted polymer