title: Pityriasis rosea-like cutaneous eruption as the presenting symptom of Hodgkin lymphoma. Case report and review of the literature.
abstract: BACKGROUND
  Cutaneous involvement by Hodgkin lymphoma is extremely rare and usually follows extensive involvement of the lymph nodes. Cutaneous manifestations of Hodgkin lymphoma may be divided into specific and non-specific. Generalized pruritus is one of the most common non-specific presentations of Hodgkin lymphoma as is cutaneous granulomas. Such signs and symptoms should prompt thorough physical exam, including evaluation of lymph nodes, especially in a young patient.
  
  
  METHODS
  We report a case of a 22-year-old man who presented with night sweats, weight loss, dry cough, and generalized maculopapular eruption that started with a large patch in the center of the chest and spread to the extremities. Biopsy of the rash revealed pityriasis rosea-like findings. A computerized tomography scan of the chest revealed a mediastinal mass. Biopsy of the mediastinal mass revealed Reed-Sternberg cells in a fibrotic background, diagnostic of Hodgkin lymphoma, nodular sclerosis type.
  
  
  CONCLUSIONS
  In conclusion, the presentation of Hodgkin lymphoma as a pityriasis rosea-like cutaneous eruption is rare and clinicians should be aware of this presentation. In this paper we review the non-specific cutaneous manifestations of Hodgkin lymphoma in an effort to raise awareness of the diversity of early cutaneous signs of Hodgkin lymphoma.
authors.affiliation: Mount Sinai Medical Center, Department of Pathology and Laboratory Medicine, Miami Beach, Florida, USA;
authors.forename: Elena
authors.initials: E
authors.lastname: Vrotsos
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Jacquelyn
authors.initials: J
authors.lastname: Dosal
authors.affiliation: Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Martin
authors.initials: M
authors.lastname: Zaiac
authors.affiliation: Mount Sinai Medical Center, Department of Pathology and Laboratory Medicine, Miami Beach, Florida, USA;
authors.forename: John
authors.initials: J
authors.lastname: Alexis
keywords: Hodgkin lymphoma; atypical pityriasis rosea; cutaneous manifestation