title: Middle ear function in sinonasal polyposis.
abstract: Nasal airway patency has long been considered a major factor in ear health. The aim of this study was to determine the effect of sinonasal polyposis on middle ear and eustachian tube (ET) functionality. Forty-four individuals with polyposis, 23 with non-polyposis nasal obstruction, and 23 healthy controls were enrolled. Demographic, clinical and imaging data of all participants were collected and ET function tests and audiologic tests were performed. Hearing loss (p = 0.02), flat tympanogram (p = 0.02), disturbed Toynbee and Valsalva tests (p = 0.01), and the prevalence of allergy (p = 0.04) and purulent nasal discharge (p < 0.001) were significantly higher in the polyposis group than the other groups. Regression analysis revealed that infection and allergy have more important roles in ET function than the nasal obstruction. Polyposis could impede ET function; however, it is probably not because of its obstructive nature, but because of the associated increased risk of infection.
authors.affiliation: Faculty of Medicine, Sinus and Surgical Endoscopic Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Bakhshaee
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Hossein Payedar
authors.initials: HP
authors.lastname: Ardakani
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Amir Hossain
authors.initials: AH
authors.lastname: Ghazizadeh
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Rahman
authors.initials: R
authors.lastname: Movahed
authors.affiliation: Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Lida
authors.initials: L
authors.lastname: Jarahi
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Ghaem Educational Hospital, Mashhad University of Medical Sciences, Mashhad, Iran. rajatim@mums.ac.ir.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Rajati
mesh_terms: D000158:Acoustic Impedance Tests; D000328:Adult; D016022:Case-Control Studies; D004432:Ear, Middle / Q000503:physiopathology*; D005064:Eustachian Tube / Q000503:physiopathology; D005260:Female; D034381:Hearing Loss / Q000209:etiology; D006801:Humans; D008297:Male; D015508:Nasal Obstruction / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D009298:Nasal Polyps / Q000150:complications / Q000503:physiopathology*; D009303:Nasopharyngeal Neoplasms / Q000150:complications; D010254:Paranasal Sinus Diseases / Q000503:physiopathology*; D012044:Regression Analysis; D012220:Rhinitis / Q000209:etiology; D013492:Suppuration / Q000209:etiology
keywords: Eustachian tube function; Middle ear; Nasal obstruction; Nasal polyposis