title: [Determination of strontium content in whole blood and urine by icp-ms].
abstract: Parameters of strontium determination in the whole blood and urine of children living near ore deposits containing up to 20% strontium sulfate have been determined. The average strontium content in the whole blood of two children groups of 109.52 ± 11.07 mg/L and 131.62 ± 12.95 mg/L, significantly exceeded the level in the comparison group 44.2 ± 4.24 mg/L. The average strontium contents of two groups of children in urine were 1252.3 ± 332.2 mg/L and 1341.5 ± 241.8 mg/L, these values were 4.2 and 4.5 times higher than in the comparison group 296.4 ± 61.5 mg/L. The conditions for blood and urine sample preparation were optimized to reduce measure errors and to determine strontium at the reference concentration level. The accuracy of the results has been confirmed by analysis of the standard samples Seronorm™ Whole Blood L1, L2, L3 and Seronorm™ Urine.
authors.affiliation: Federal Scientific Center for Medical and Prophylactic Health Risk Management Technologies, Perm, Russia.
authors.forename: T S
authors.initials: TS
authors.lastname: Ulanova
authors.affiliation: Federal Scientific Center for Medical and Prophylactic Health Risk Management Technologies, Perm, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Gileva
authors.affiliation: Federal Scientific Center for Medical and Prophylactic Health Risk Management Technologies, Perm, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Stenno
authors.affiliation: Federal Scientific Center for Medical and Prophylactic Health Risk Management Technologies, Perm, Russia.
authors.forename: G A
authors.initials: GA
authors.lastname: Veikhman
authors.affiliation: Federal Scientific Center for Medical and Prophylactic Health Risk Management Technologies, Perm, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Nedochitova
mesh_terms: D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D060766:Drinking Water / Q000032:analysis / Q000737:chemistry; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D012426:Russia; D013054:Spectrophotometry, Atomic; D013324:Strontium / Q000008:administration & dosage / Q000097:blood* / Q000652:urine*
chemical_list: D060766:Drinking Water; D013324:Strontium
keywords: inductively coupled plasma; internal standard; mass spectrometry; reaction/collision cell; strontium; urine; whole blood