title: Induction chemotherapy for oral cavity cancer patients: Current status and future perspectives.
abstract: There is a lack of data from phase III randomized studies to support an ideal approach for locally advanced oral cavity cancer patients. In general, surgery, radiotherapy and chemotherapy are valid treatment options, and combined approach is usually indicated given poor clinical outcomes with single modality therapy. The aim of this study is to review the current status and future perspectives of induction chemotherapy for locally advanced oral cavity cancer patients.
authors.affiliation: Department of Radiation Oncology, Hospital Sírio-Libanês and Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, Brazil. Electronic address: gnmarta@uol.com.br.
authors.forename: Gustavo Nader
authors.initials: GN
authors.lastname: Marta
authors.affiliation: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, USA. Electronic address: wnwillia@mdanderson.org.
authors.forename: William N
authors.initials: WN
authors.lastname: William
authors.affiliation: Department of Medical Oncology, Hospital Sírio-Libanês and Instituto do Câncer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, Brazil. Electronic address: omfeher@gmail.com.
authors.forename: Olavo
authors.initials: O
authors.lastname: Feher
authors.affiliation: Department of Head and Neck Cancer, Hospital do Câncer de Barretos, Fundação Pio XII, Brazil. Electronic address: alopescarvalho@uol.com.br.
authors.forename: André Lopes
authors.initials: AL
authors.lastname: Carvalho
authors.affiliation: Department of Head and Neck Surgery and Otorhinolaryngology, A.C. Camargo Cancer Center, Brazil. Electronic address: lp_kowalski@uol.com.br.
authors.forename: Luiz Paulo
authors.initials: LP
authors.lastname: Kowalski
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D060828:Induction Chemotherapy / Q000379:methods*; D007822:Laryngeal Neoplasms / Q000188:drug therapy*; D009062:Mouth Neoplasms / Q000188:drug therapy*; D009959:Oropharyngeal Neoplasms / Q000188:drug therapy; D010610:Pharyngeal Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
keywords: Induction chemotherapy; Neoplasms; Oral cavity; Radiotherapy; Surgery; Treatment