title: Emerging interactions between matrix components during biofilm development.
abstract: Bacterial cells are most often found in the form of multicellular aggregates commonly referred to as biofilms. Biofilms offer their member cells several benefits, such as resistance to killing by antimicrobials and predation. During biofilm formation there is a production of extracellular substances that, upon assembly, constitute an extracellular matrix. The ability to generate a matrix encasing the microbial cells is a common feature of biofilms, but there is diversity in matrix composition and in interaction between matrix components. The different components of bacterial biofilm extracellular matrixes, known as matrix interactions, and resulting implications are discussed in this review.
authors.affiliation: Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
authors.forename: David E
authors.initials: DE
authors.lastname: Payne
authors.affiliation: Department of Microbiology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA. blaise-boles@uiowa.edu.
authors.forename: Blaise R
authors.initials: BR
authors.lastname: Boles
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism; D018441:Biofilms; D004269:DNA, Bacterial; D005109:Extracellular Matrix / Q000378:metabolism*; D005110:Extracellular Space; D016680:Genome, Bacterial; D011135:Polysaccharides, Bacterial / Q000378:metabolism; D013211:Staphylococcus aureus / Q000502:physiology
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D011135:Polysaccharides, Bacterial
keywords: Biofilm; Functional amyloids; Polysaccharide; Staphylococcus aureus; eDNA