title: Tablet: Visualizing Next-Generation Sequence Assemblies and Mappings.
abstract: This chapter is designed to be a practical guide to using Tablet for the visualization of next/second-generation (NGS) sequencing data. NGS data is being produced more frequently and in greater data volumes every year. As such, it is increasingly important to have tools which enable biologists and bioinformaticians to understand and gain key insights into their data. Visualization can play a key role in the exploration of such data as well as aid in the visual validation of sequence assemblies and features such as single nucleotide polymorphisms (SNPs). We aim to show several use cases which demonstrate Tablet's ability to visually highlight various situations of interest which can arise in NGS data.
authors.affiliation: Information and Computational Sciences, The James Hutton Institute, Invergowrie, Dundee, Scotland, UK. iain.milne@hutton.ac.uk.
authors.forename: Iain
authors.initials: I
authors.lastname: Milne
authors.affiliation: Information and Computational Sciences, The James Hutton Institute, Invergowrie, Dundee, Scotland, UK.
authors.forename: Micha
authors.initials: M
authors.lastname: Bayer
authors.affiliation: Information and Computational Sciences, The James Hutton Institute, Invergowrie, Dundee, Scotland, UK.
authors.forename: Gordon
authors.initials: G
authors.lastname: Stephen
authors.affiliation: Information and Computational Sciences, The James Hutton Institute, Invergowrie, Dundee, Scotland, UK.
authors.forename: Linda
authors.initials: L
authors.lastname: Cardle
authors.affiliation: Information and Computational Sciences, The James Hutton Institute, Invergowrie, Dundee, Scotland, UK.
authors.forename: David
authors.initials: D
authors.lastname: Marshall
mesh_terms: D002874:Chromosome Mapping / Q000379:methods*; D019295:Computational Biology / Q000379:methods*; D023281:Genomics / Q000379:methods*; D059014:High-Throughput Nucleotide Sequencing; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D064878:Web Browser
keywords: Assembly; Mapping; Next-generation sequencing; SNP discovery; Visualization