title: Percutaneous aortic valve closure for patients with left ventricular assist device-associated aortic insufficiency.
abstract: The development of de novo aortic insufficiency (AI) is a significant complication of long-term LVAD support, which can lead to ineffective support, decreased device durability, end organ malperfusion, and increased mortality. Surgical aortic valve (AV) closure has been the standard treatment for symptomatic patients, but is associated with high mortality and recurrence of AI. Percutaneous AV closure using the Amplatzer cribriform device is a feasible and may be the preferable option to treat LVAD-associated severe AI in high-surgical risk patients. Certain technical issues with this procedure should be taken into consideration to achieve optimal results. © 2015 Wiley Periodicals, Inc.
authors.affiliation: Division of Cardiovascular Diseases, University of Rochester Medical Center, Rochester, New York.
authors.forename: Mohamad
authors.initials: M
authors.lastname: Alkhouli
authors.affiliation: Division of Cardiovascular Diseases, University of Rochester Medical Center, Rochester, New York.
authors.forename: Betsy
authors.initials: B
authors.lastname: Melito
authors.affiliation: Division of Cardiovascular Diseases, University of Rochester Medical Center, Rochester, New York.
authors.forename: Frederick S
authors.initials: FS
authors.lastname: Ling
mesh_terms: D000369:Aged, 80 and over; D000497:Alloys; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006328:Cardiac Catheterization / Q000295:instrumentation; D018618:Echocardiography, Doppler, Color; D017548:Echocardiography, Transesophageal; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008297:Male; D016062:Porosity; D011474:Prosthesis Design; D015641:Radiography, Interventional; D055989:Septal Occluder Device; D016896:Treatment Outcome; D016277:Ventricular Function, Left
chemical_list: D000497:Alloys; C013616:nitinol
keywords: amplatzer cribriform septal occlude; aortic insufficiency; aortic valve closure; left ventricular assist device