title: [Development of a New Method for Determination of Sodium Saccharin and Acesulfame Potassium with the Aid of Coagulant].
abstract: An HPLC method for determination of sodium saccharin and acesulfame potassium was newly developed, employing coagulant pretreatment to remove particles dispersed in the sample extract. The method showed recovery of 96-101% for both analytes with a repeatability of less than 1% and a reproducibility of less than 2%. The limit of quantification for sodium saccharin was 0.025 g/kg and that for acesulfame potassium was 0.025 g/kg. Only about 20 min was required for preparation of the test solution, whereas the dialysis method takes much longer.
authors.affiliation: Nagoya City Public Health Research Institute.
authors.forename: Jun
authors.initials: J
authors.lastname: Sugiura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakajima
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003029:Coagulants; D005504:Food Analysis / Q000379:methods*; D015203:Reproducibility of Results; D012439:Saccharin / Q000032:analysis*; D012996:Solutions; D013549:Sweetening Agents / Q000032:analysis*; D013843:Thiazines / Q000032:analysis*; D013997:Time Factors
chemical_list: D003029:Coagulants; D012996:Solutions; D013549:Sweetening Agents; D013843:Thiazines; D012439:Saccharin; C006362:acetosulfame