title: Fatty acids composition of human milk fed to small for gestational age infants.
abstract: OBJECTIVE
  To test the null hypothesis that mothers of asymmetric small for gestational age (SGA) infants produce milk with fatty acids composition similar to that of lactating mothers of appropriate-for-gestational-age (AGA) infants.
  
  
  METHODS
  We obtained human milk (HM) from 2 groups of lactating volunteers that gave birth to asymmetric SGA (study group) or AGA infants (control group). Each mother was asked to contribute by manual expression at least one of 3 samples: first 72 hours after labor (colostrum), day 2-7 postpartum (transitional milk) and 14 days post partum (mature milk). After lipid extraction using Folch's cold-extraction procedure fatty acids were analyzed using gas chromatography.
  
  
  RESULTS
  A total of 108 samples were obtained in 60 women. In univariate analysis, there were no significant differences in any of the fatty acids concentrations examined between groups. This remained true when timing of the sample (colostrum, transitional or mature milk) or gestational age were introduced as confounders in analysis of variance (general linear model).
  
  
  CONCLUSIONS
  Fatty acid composition of human milk is not affected by whether or not the infant was fetal growth restricted. We suggest that mothers of SGA infants may be reassured about the fat quality of their milk.
authors.affiliation: a Departments of Neonatology and Pediatrics , Tel Aviv Medical Center , Tel Aviv , Israel .|b Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.
authors.forename: Ronit
authors.initials: R
authors.lastname: Lubetzky
authors.affiliation: c Departments of Animal Science and Biochemistry and Food , The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem , Israel.
authors.forename: Nurit
authors.initials: N
authors.lastname: Argov-Argaman
authors.affiliation: a Departments of Neonatology and Pediatrics , Tel Aviv Medical Center , Tel Aviv , Israel .|b Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.
authors.forename: Francis B
authors.initials: FB
authors.lastname: Mimouni
authors.affiliation: a Departments of Neonatology and Pediatrics , Tel Aviv Medical Center , Tel Aviv , Israel .
authors.forename: Keren
authors.initials: K
authors.lastname: Armoni Domany
authors.affiliation: a Departments of Neonatology and Pediatrics , Tel Aviv Medical Center , Tel Aviv , Israel .
authors.forename: Yaffa
authors.initials: Y
authors.lastname: Shiff
authors.affiliation: c Departments of Animal Science and Biochemistry and Food , The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem , Israel.
authors.forename: Zipi
authors.initials: Z
authors.lastname: Berkovitz
authors.affiliation: c Departments of Animal Science and Biochemistry and Food , The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem , Israel.
authors.forename: Ram
authors.initials: R
authors.lastname: Reifen
authors.affiliation: a Departments of Neonatology and Pediatrics , Tel Aviv Medical Center , Tel Aviv , Israel .|b Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.
authors.forename: Dror
authors.initials: D
authors.lastname: Mandel
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003126:Colostrum / Q000737:chemistry; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D016014:Linear Models; D008895:Milk, Human / Q000737:chemistry*
chemical_list: D005227:Fatty Acids
keywords: Fat; fatty acids; human milk; small for gestation