title: Epidemiological characterization of diabetic patients on therapy with continuous subcutaneous insulin infusion and continuous glucose monitoring in real time.
abstract: OBJECTIVE
  To describe baseline characteristics of diabetic patients who were started on insulin pump and real time continuous glucose monitor (CSII-rtCGM) in a specialized center in Medellin, Colombia.
  
  
  METHODS
  All patients with diabetes with complete data who were started on CSII-rtCGM between February 2010 and May 2014 were included. This is a descriptive analysis of the sociodemographic and clinical characteristics.
  
  
  RESULTS
  141 of 174 patients attending the clinic were included. 90,1% had type 1diabetes (T1D). The average age of T1D patients at the beginning of therapy was 31,4 years (SD 14,1). 75.8% of patients had normal weight (BMI<25), 21.0% were overweight (BMI 25-30) and 2,3% were obese (BMI>30). The median duration of T1D was 13 years (P25-P75=10.7-22.0). 14,2% of the patients were admitted at least once in the year preceding the start of CSII-rtCGM because of diabetes related complications. Mean A1c was 8.6%±1.46%. The main reasons for starting CSII-rtCGM were: poor glycemic control (50.2%); frequent hypoglycemia, nocturnal hypoglycemia, hypoglycemia related to exercise, asymptomatic hypoglycemia (30.2%); severe hypoglycemia (16.44%) and dawn phenomena (3.1%).
  
  
  CONCLUSIONS
  Baseline characteristics of patients included in this study who were started on CSII-rtCGM are similar to those reported in the literature. The Clinic starts CSII-rtCGM mainly in T1D patients with poor glycemic control, frequent or severe hypoglycemia despite being on basal/bolus therapy.
authors.affiliation: Universidad Pontificia Bolivariana, Medellín, Colombia; Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia. Electronic address: direccion.cientifica@clidiabetes.com.
authors.forename: Natalia
authors.initials: N
authors.lastname: Aristizábal
authors.affiliation: Universidad Pontificia Bolivariana, Medellín, Colombia; Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia.
authors.forename: Alex
authors.initials: A
authors.lastname: Ramírez
authors.affiliation: Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia; Clínica Integral de Diabetes , Medellín, Colombia; Grupo de Promoción y Prevención Farmacéutica, Universidad de Antioquía, Medellín, Colombia.
authors.forename: Jaime
authors.initials: J
authors.lastname: Hincapié-García
authors.affiliation: Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia; Clínica Integral de Diabetes , Medellín, Colombia.
authors.forename: Estefany
authors.initials: E
authors.lastname: Laiton
authors.affiliation: Universidad CES , Medellín, Colombia.
authors.forename: Carolina
authors.initials: C
authors.lastname: Aristizábal
authors.affiliation: Universidad Pontificia Bolivariana, Medellín, Colombia.
authors.forename: Diana
authors.initials: D
authors.lastname: Cuesta
authors.affiliation: Universidad Pontificia Bolivariana, Medellín, Colombia; Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia; Clínica Integral de Diabetes , Medellín, Colombia.
authors.forename: Claudia
authors.initials: C
authors.lastname: Monsalve
authors.affiliation: Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia; Clínica Integral de Diabetes , Medellín, Colombia.
authors.forename: Gloria
authors.initials: G
authors.lastname: Hincapié
authors.affiliation: Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia; Clínica Integral de Diabetes , Medellín, Colombia.
authors.forename: Eliana
authors.initials: E
authors.lastname: Zapata
authors.affiliation: Clínica Integral de Diabetes , Medellín, Colombia.
authors.forename: Verónica
authors.initials: V
authors.lastname: Abad
authors.affiliation: Clínica Integral de Diabetes , Medellín, Colombia.
authors.forename: Maria-Rocio
authors.initials: MR
authors.lastname: Delgado
authors.affiliation: Universidad Pontificia Bolivariana, Medellín, Colombia; Servicio Endocrinología, Clínica Las Américas, Medellín, Colombia.
authors.forename: José-Luis
authors.initials: JL
authors.lastname: Torres
authors.affiliation: Universidad Pontificia Bolivariana, Medellín, Colombia; Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia; Clínica Integral de Diabetes , Medellín, Colombia.
authors.forename: Andrés
authors.initials: A
authors.lastname: Palacio
authors.affiliation: Universidad Pontificia Bolivariana, Medellín, Colombia; Grupo de investigación Innovación, Desarrollos y Avances en Endocrinología IDEAS , Medellín, Colombia; Clínica Integral de Diabetes , Medellín, Colombia.
authors.forename: José
authors.initials: J
authors.lastname: Botero
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000886:Anthropometry; D001786:Blood Glucose / Q000032:analysis; D015190:Blood Glucose Self-Monitoring / Q000295:instrumentation / Q000379:methods*; D015897:Comorbidity; D003199:Computer Systems; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D015918:Infusion Pumps, Implantable; D055104:Infusions, Subcutaneous; D007328:Insulin / Q000008:administration & dosage* / Q000627:therapeutic use; D007332:Insulin Infusion Systems; D008297:Male; D008875:Middle Aged; D050177:Overweight / Q000453:epidemiology; D012959:Socioeconomic Factors; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin
keywords: Continuous insulin infusion system; Diabetes; Sistemas de infusión de insulina