title: Dataset for the quantitative proteomics analysis of the primary hepatocellular carcinoma with single and multiple lesions.
abstract: Hepatocellular Carcinoma (HCC) is one of the most common malignant tumor, which is causing the second leading cancer-related death worldwide. The tumor tissues and the adjacent noncancerous tissues obtained from HCC patients with single and multiple lesions were quantified using iTRAQ. A total of 5513 proteins (FDR of 1%) were identified which correspond to roughly 27% of the total liver proteome. And 107 and 330 proteins were dysregulated in HCC tissue with multiple lesions (MC group) and HCC tissue with a single lesion (SC group), compared with their noncancerous tissue (MN and SN group) respectively. Bioinformatics analysis (GO, KEGG and IPA) allowed these data to be organized into distinct categories. The data accompanying the manuscript on this approach (Xing et al., J. Proteomics (2015), http://dx.doi.org/10.1016/j.jprot.2015.08.007[1]) have been deposited to the iProX with identifier IPX00037601.
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China.
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Xing
authors.affiliation: Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People's Republic of China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Huang
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China.
authors.forename: Sen
authors.initials: S
authors.lastname: Wang
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China ; Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People's Republic of China.
authors.forename: Minhui
authors.initials: M
authors.lastname: Chi
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China ; Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People's Republic of China.
authors.forename: Yongyi
authors.initials: Y
authors.lastname: Zeng
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China ; Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People's Republic of China.
authors.forename: Lihong
authors.initials: L
authors.lastname: Chen
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China ; Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People's Republic of China.
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China ; Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People's Republic of China.
authors.forename: Jinhua
authors.initials: J
authors.lastname: Zeng
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China.
authors.forename: Minjie
authors.initials: M
authors.lastname: Lin
authors.affiliation: Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, People's Republic of China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Han
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China ; Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350007, People's Republic of China.
authors.forename: Jingfeng
authors.initials: J
authors.lastname: Liu
authors.affiliation: The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, People's Republic of China ; The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, People's Republic of China.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Liu