title: Prevalence and Determinants of Metabolic Health in Subjects with Obesity in Chinese Population.
abstract: BACKGROUND
  The study was to investigate the prevalence of metabolic health in subjects with obesity in the Chinese population and to identify the determinants related to metabolic abnormality in obese individuals.
  
  
  METHODS
  5013 subjects were recruited from seven provincial capitals in China. The obesity and metabolic status were classified based on body mass index (BMI) and the number of abnormalities in common components of metabolic syndrome.
  
  
  RESULTS
  27.9% of individuals with obesity were metabolically healthy. The prevalence of the metabolically healthy obese (MHO) phenotype was significantly decreased with age in women (p trend < 0.001), but not significantly in men (p trend = 0.349). Central obesity (odds ratio [OR] = 4.07, 95% confidence interval [CI] = 1.93-8.59), longer sedentary time (OR = 1.97, 95%CI = 1.27-3.06), and with a family history of obesity related diseases (hypertension, diabetes, dyslipidemia) (OR = 1.85, 95%CI = 1.26-2.71) were significantly associated with having metabolic abnormality in obese individuals. Higher levels of physical activity and more fruit/vegetable intake had decreased ORs of 0.67 (95%CI = 0.45-0.98) and 0.44 (95%CI = 0.28-0.70), respectively.
  
  
  CONCLUSIONS
  27.9% of obese participants are in metabolic health. Central obesity, physical activity, sedentary time, fruits/vegetables intake and family history of diseases are the determinants associated with metabolic status in obesity.
authors.affiliation: Department of Epidemiology & Biostatistics, School of Public Health, Zhejiang University, Hangzhou 310058, China. canprezrz@126.com.
authors.forename: Ruizhi
authors.initials: R
authors.lastname: Zheng
authors.affiliation: Department of Nutrition, School of Public Health, Zhejiang University, Hangzhou 310058, China. ymin36@zju.edu.cn.
authors.forename: Min
authors.initials: M
authors.lastname: Yang
authors.affiliation: Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China. byq522@163.com.
authors.forename: Yuqian
authors.initials: Y
authors.lastname: Bao
authors.affiliation: Department of Endocrinology, Sir Run Run Shaw Hospital, Affiliated to School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang, China. lihongheyi@126.com.
authors.forename: Hong
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Endocrinology and Metabolism, The First Affiliated Hospital, China Medical University, Beier Road No. 92, Shenyang 110001, China. shanzhongyan@medmail.com.cn.
authors.forename: Zhongyan
authors.initials: Z
authors.lastname: Shan
authors.affiliation: Department of Endocrinology, China-Japan Friendship Hospital, Beijing 100029, China. drbozhang@yahoo.com.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.affiliation: Department of Endocrinology and Diabetes Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China. Liujuan8093@126.com.
authors.forename: Juan
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China. lqg3713@163.com.
authors.forename: Qinguo
authors.initials: Q
authors.lastname: Lv
authors.affiliation: Department of Chronic and Noncommunicable Disease Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou 310021, China. wuou1@163.com.
authors.forename: Ou
authors.initials: O
authors.lastname: Wu
authors.affiliation: Department of Epidemiology & Biostatistics, School of Public Health, Zhejiang University, Hangzhou 310058, China. zhuym@zju.edu.cn.
authors.forename: Yimin
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Department of Pathology, Zhejiang University School of Medicine, Hangzhou 310058, China. lmp@zju.edu.cn.
authors.forename: Maode
authors.initials: M
authors.lastname: Lai
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D002947:Cities / Q000453:epidemiology; D003920:Diabetes Mellitus; D004032:Diet; D050171:Dyslipidemias; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000378:metabolism; D056128:Obesity, Abdominal / Q000453:epidemiology; D016017:Odds Ratio; D015995:Prevalence
keywords: dietary; metabolic; obesity; prevalence; public health