title: MicroRNA-7: a promising new target in cancer therapy.
abstract: The incidence of tumors with life-threatening effects has increased gradually over time; however, the mechanisms involved in tumor development have not been fully elucidated. Recent studies have shown that microRNA-7 (miR-7), which is endogenous non-coding RNA molecules of approximately 23 nucleotides, plays an important role in the occurrence and development of tumors as a key tumor suppressor. Mechanistic evidence showed that miR-7 is closely related to the growth, metastasis, and prognosis of various malignant tumors through regulating different target molecules, which suggest that miR-7 may be a new target for the clinical diagnosis and treatment of various tumors. In this review, we summarize current knowledge of the relationship between miR-7 and tumor development, diagnosis, and treatment.
authors.affiliation: Department of Immunology, Zunyi Medical College, Guizhou, 563000 People's Republic of China.
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Department of Immunology, Zunyi Medical College, Guizhou, 563000 People's Republic of China.
authors.forename: Yijing
authors.initials: Y
authors.lastname: Tao
authors.affiliation: Department of Medical Physics, Zunyi Medical College, Guizhou, 563000 China.
authors.forename: Ya
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Department of Immunology, Zunyi Medical College, Guizhou, 563000 People's Republic of China.
authors.forename: Nalin
authors.initials: N
authors.lastname: Qin
authors.affiliation: Department of Immunology, Zunyi Medical College, Guizhou, 563000 People's Republic of China.
authors.forename: Chao
authors.initials: C
authors.lastname: Chen
authors.affiliation: Department of Immunology, Zunyi Medical College, Guizhou, 563000 People's Republic of China.
authors.forename: Dan
authors.initials: D
authors.lastname: Tian
authors.affiliation: Department of Immunology, Zunyi Medical College, Guizhou, 563000 People's Republic of China.
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
keywords: Diagnosis; MiR-7; Treatment; Tumors