title: Stevens-Johnson syndrome induced by a combination of lamotrigine and valproic acid.
abstract: Lamotrigine and valproic acid are well-tolerated anticonvulsants, but frequently associated with severe cutaneous reactions, such as the Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis, when used in combination. We report a case of SJS likely induced by the use of a lamotrigine and valproic acid regimen and as a dental surgeon it is important to identify such lesion and report to pharmacovigilance.
authors.affiliation: Department of Oral Pathology and Microbiology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Kavitha
authors.affiliation: Department of Pharmacology, Tagore Medical College, Chennai, Tamil Nadu, India.
authors.forename: T
authors.initials: T
authors.lastname: Anbuchelvan
authors.affiliation: Department of Oral Pathology and Microbiology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India.
authors.forename: V
authors.initials: V
authors.lastname: Mahalakshmi
authors.affiliation: Department of Oral Pathology and Microbiology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India.
authors.forename: R
authors.initials: R
authors.lastname: Sathya
authors.affiliation: Department of Oral Pathology and Microbiology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India.
authors.forename: T R
authors.initials: TR
authors.lastname: Sabarinath
authors.affiliation: Department of Oral Pathology and Microbiology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India.
authors.forename: N
authors.initials: N
authors.lastname: Gururaj
authors.affiliation: Department of Periodontics, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Kalaivani
keywords: Lamotrigine; Stevens–Johnson syndrome; toxic epidermal necrolysis; valproic acid