title: [Yellow-nail-Syndrome associated with chronic sinusitis and recurrent pneumonias].
abstract: METHODS
  In a 58-year-old man progressive yellowing of all nails was associated with the diagnosis of chronic rhinosinusitis and COPD, later the COPD exacerbated with pneumonias.
  
  
  METHODS
  Repeated fungal cultures and polymerase chain reactions to detect fungal DNA in order to exclude Onychomycosis, chest X-ray, computed tomography of the lung, extended pulmonary function tests, ECG, echocardiography and abdominal ultrasonography were performed and had normal results.
  
  
  METHODS
  Normal fingernails regrew after a 6 month-course of vitamin E intake, most of the toenails remained coloured and thickened. After the initial presentation at the dermatological outpatient department the pulmonary situation remained stable, there was no need for additional pulmonary interventions.
  
  
  CONCLUSIONS
  Yellowing of all nails is a diagnostic sign of the Yellow-nail-Syndrome, which is associated with respiratory diseases, the treatment is often difficult and also an interdisciplinary approach is needed.
authors.affiliation: Klinik für Hautkrankheiten des Universitätsklinikums Jena.
authors.forename: Claudia
authors.initials: C
authors.lastname: Schummer
authors.affiliation: Klinik für Hautkrankheiten des Universitätsklinikums Jena.
authors.forename: Jörg
authors.initials: J
authors.lastname: Tittelbach
authors.affiliation: Klinik für Innere Medizin, Hufeland Klinikum, Standort Bad Langensalza.
authors.forename: Matthias
authors.initials: M
authors.lastname: Oehler
authors.affiliation: Klinik für Innere Medizin, Hufeland Klinikum, Standort Bad Langensalza.
authors.forename: Thomas
authors.initials: T
authors.lastname: Höhn
authors.affiliation: Klinik für Hautkrankheiten des Universitätsklinikums Jena.
authors.forename: Peter
authors.initials: P
authors.lastname: Elsner
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009262:Nails / Q000473:pathology; D011014:Pneumonia; D012852:Sinusitis; D056684:Yellow Nail Syndrome