title: Anti-IFN-γ autoantibodies are strongly associated with HLA-DR*15:02/16:02 and HLA-DQ*05:01/05:02 across Southeast Asia.
authors.affiliation: Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan; Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan; Chang Gung Immunology Consortium, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan. Electronic address: clku@mail.cgu.edu.tw.
authors.forename: Cheng-Lung
authors.initials: CL
authors.lastname: Ku
authors.affiliation: Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.
authors.forename: Chia-Hao
authors.initials: CH
authors.lastname: Lin
authors.affiliation: Clinical Informatics and Medical Statistics Research Center, Chang Gung University, Taoyuan, Taiwan.
authors.forename: Su-Wei
authors.initials: SW
authors.lastname: Chang
authors.affiliation: Immunogenetics Laboratory, Medical Research Department, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Chen-Chung
authors.initials: CC
authors.lastname: Chu
authors.affiliation: State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, The University of Hong Kong Queen Mary Hospital, Hong Kong, China.
authors.forename: Jasper F W
authors.initials: JF
authors.lastname: Chan
authors.affiliation: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY.
authors.forename: Xiao-Fei
authors.initials: XF
authors.lastname: Kong
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
authors.forename: Chen-Hsiang
authors.initials: CH
authors.lastname: Lee
authors.affiliation: Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
authors.forename: Emily A
authors.initials: EA
authors.lastname: Rosen
authors.affiliation: Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.
authors.forename: Jing-Ya
authors.initials: JY
authors.lastname: Ding
authors.affiliation: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Wen-I
authors.initials: WI
authors.lastname: Lee
authors.affiliation: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM-U1163, Paris, France; Imagine Institute, Paris Descartes University, Paris, France.
authors.forename: Jacinta
authors.initials: J
authors.lastname: Bustamante
authors.affiliation: Clinic for Immunology and Rheumatology, Medical School of Hanover, Hanover, Germany.
authors.forename: Torsten
authors.initials: T
authors.lastname: Witte
authors.affiliation: Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.
authors.forename: Han-Po
authors.initials: HP
authors.lastname: Shih
authors.affiliation: Laboratory of Human Immunology and Infectious Diseases, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan; Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
authors.forename: Chen-Yen
authors.initials: CY
authors.lastname: Kuo
authors.affiliation: Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand.
authors.forename: Ploenchan
authors.initials: P
authors.lastname: Chetchotisakd
authors.affiliation: Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand.
authors.forename: Sasisopin
authors.initials: S
authors.lastname: Kiertiburanakul
authors.affiliation: Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Yupin
authors.initials: Y
authors.lastname: Suputtamongkol
authors.affiliation: State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, The University of Hong Kong Queen Mary Hospital, Hong Kong, China.
authors.forename: Kwok-Yung
authors.initials: KY
authors.lastname: Yuen
authors.affiliation: St Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM-U1163, Paris, France; Imagine Institute, Paris Descartes University, Paris, France; Howard Hughes Medical Institute, New York, NY; Pediatric Immuno-Hematology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.
authors.forename: Jean-Laurent
authors.initials: JL
authors.lastname: Casanova
authors.affiliation: Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Holland
authors.affiliation: Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, United Kingdom; National Institute for Health Research, Cambridge Biomedical Research Center, Cambridge, United Kingdom.
authors.forename: Rainer
authors.initials: R
authors.lastname: Doffinger
authors.affiliation: Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
authors.forename: Sarah K
authors.initials: SK
authors.lastname: Browne
authors.affiliation: Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
authors.forename: Chih-Yu
authors.initials: CY
authors.lastname: Chi
mesh_terms: D000483:Alleles; D001210:Asia, Southeastern; D044466:Asian People / Q000235:genetics*; D001323:Autoantibodies / Q000276:immunology*; D056726:Genetic Association Studies; D006683:HLA-DQ Antigens / Q000235:genetics* / Q000276:immunology*; D059866:HLA-DQ beta-Chains / Q000235:genetics / Q000276:immunology; D006684:HLA-DR Antigens / Q000235:genetics* / Q000276:immunology*; D059811:HLA-DRB1 Chains / Q000235:genetics / Q000276:immunology; D006650:Histocompatibility Testing; D006801:Humans; D007371:Interferon-gamma / Q000037:antagonists & inhibitors*
chemical_list: D001323:Autoantibodies; D006683:HLA-DQ Antigens; D059866:HLA-DQ beta-Chains; C069051:HLA-DQB1 antigen; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D007371:Interferon-gamma