title: [Bisphosphonate].
abstract: Bisphosphonates (BPs) are first-line drugs in the management of osteoporosis. BPs' significant efficacy in the prevention of vertebral, non-vertebral, and hip fractures has been proven. BPs are now available as an injection as well as as oral administration in Japan. This review gives an overview of the efficacy as well as the clinical issues of the bisphosphonates.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hagino
mesh_terms: D015519:Bone Density / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004164:Diphosphonates / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy*; D058866:Osteoporotic Fractures / Q000188:drug therapy; D011379:Prognosis
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates