title: [Preliminary results of chronic intrathecal therapy in treatment of spastic syndromes of various etiologies].
abstract: To estimate the effectiveness of the chronic intrathecal baclofen infusion (ITB) for the treatment of botuloresistant spastic disorders.
  
  
  
  ITB have been performed in 15 cases of spastic disorders. In 8 cases spasticity was the result of cerebral palsy, 5 - spinal cord injure, 1 - cerebral injure, 1 - pyogenic spinal epiduritis. The results of surgical treatment were estimated with the Ashworth, GMFM-88 and Arens scales. These data have been exposed statistically analysis.
  
  
  
  Significantly decrease of spasticity have been revealed in most cases: from 4.26±0.7 points before the operation to 1.8±0.67 points after the operation (p<0.004). In 8 cases we have observed improvement in motor functions.
  
  
  
  ITB is an effective procedure which leads to decreasing of spasticity, incree of movement volume and improvement in motor functions in patients with spastic disorders.
authors.affiliation: Burdenko Neurosurgical Institute, Moscow, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Dekopov
authors.affiliation: Burdenko Neurosurgical Institute, Moscow, Russia.
authors.forename: V A
authors.initials: VA
authors.lastname: Shabalov
authors.affiliation: Burdenko Neurosurgical Institute, Moscow, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Tomskiy
authors.affiliation: Burdenko Neurosurgical Institute, Moscow, Russia.
authors.forename: I O
authors.initials: IO
authors.lastname: Gaevyi
authors.affiliation: Burdenko Neurosurgical Institute, Moscow, Russia.
authors.forename: E M
authors.initials: EM
authors.lastname: Salova
mesh_terms: D000328:Adult; D001418:Baclofen / Q000008:administration & dosage / Q000627:therapeutic use*; D001930:Brain Injuries / Q000188:drug therapy*; D002547:Cerebral Palsy / Q000188:drug therapy*; D002648:Child; D006801:Humans; D060186:Infusions, Spinal; D009125:Muscle Relaxants, Central / Q000008:administration & dosage / Q000627:therapeutic use*; D013119:Spinal Cord Injuries / Q000188:drug therapy*
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen