title: Chemical composition of the essential oil from Thapsia garganica L. (Apiaceae) grown wild in Sicily and its antimicrobial activity.
abstract: In this study, the chemical composition of the essential oil from flowers and leaves of Thapsia garganica L. collected in Sicily was evaluated by GC and GC-MS. The main components of T. garganica flower oil (T.f.) were chamazulene (58.3%), humulene oxide II (9.0%), tricosane (8.2%) and pentacosane (8.2%). Also the oil from leaves (T.l.) was characterised by high content of chamazulene (49.2%). Other abundant metabolites were 1,4-dimethylazulene (18.5%), (E)-phytol (6.3%) and neophytadiene (5.1%). The comparison with other studied oils of genus Thapsia is discussed. Antimicrobial activity against several micro-organisms, including some ones infesting historical art craft, was also determined.
authors.affiliation: a Department STEBICEF , University of Palermo , Palermo , Italy.
authors.forename: Simona
authors.initials: S
authors.lastname: Casiglia
authors.affiliation: a Department STEBICEF , University of Palermo , Palermo , Italy.
authors.forename: Luana
authors.initials: L
authors.lastname: Riccobono
authors.affiliation: a Department STEBICEF , University of Palermo , Palermo , Italy.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bruno
authors.affiliation: a Department STEBICEF , University of Palermo , Palermo , Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Rosselli
authors.affiliation: b Department of Pharmacy , University of Salerno , Fisciano , Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Senatore
authors.affiliation: c Department of Pharmacy , University of Naples "Federico II" , Naples , Italy.
authors.forename: Felice
authors.initials: F
authors.lastname: Senatore
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D035264:Flowers / Q000737:chemistry; D005658:Fungi / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D012802:Sicily; D053629:Thapsia / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D009822:Oils, Volatile
keywords: 1,4-dimethylazulene; Apiaceae; Thapsia garganica; antimicrobial activity; chamazulene; humulene oxide II; volatile components