title: [Economic evaluation of the treatments of non-metastatic prostate cancer].
abstract: OBJECTIVE
  Prostate cancer is the most frequent cancer and the third leading cause of cancer death in men in France. The development of treatment for prostate cancer is fast and sometimes relies on costly innovations. Medico-economic studies are however rare in this area. This literature review aims to summarize available medico-economic data on the initial management of localized prostate cancer and discuss the quality and usability of existing economic studies on the subject.
  
  
  METHODS
  Literature review was done using PubMed and Cochrane databases. Studies and articles were selected based on several criteria: population with initial treatment for localized prostate cancer (without metastasis), comparative studies with surgery as control treatment, studies in countries members of the OECD, articles in English or French published between 2004 and 2014.
  
  
  RESULTS
  The surgical robot, one of the newest innovations, is more expensive than conventional open surgery or no robotic laparoscopy, even if it is associated with a reduction of the original period of stay. Radiation therapy seems more expensive than surgery as initial therapy of localized prostate cancer.
  
  
  CONCLUSIONS
  Conclusions remain limited because of the rarity of reliable health economic studies on the subject.
authors.affiliation: URC-Eco (unité de recherche clinique spécialisée en économie de la santé), Hôtel-Dieu, AP-HP, 1, place du Parvis-Notre-Dame, 75004 Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Perlbarg
authors.affiliation: URC-Eco (unité de recherche clinique spécialisée en économie de la santé), Hôtel-Dieu, AP-HP, 1, place du Parvis-Notre-Dame, 75004 Paris, France.
authors.forename: H
authors.initials: H
authors.lastname: Rabetrano
authors.affiliation: Département d'urologie-andrologie-transplantation rénale, CHU Rangueil, 1, avenue Jean-Poulhès, 31059 Toulouse cedex 9, France.
authors.forename: M
authors.initials: M
authors.lastname: Soulié
authors.affiliation: Service d'urologie et de transplantation rénale et pancréatique, CHU Mondor, 51, avenue Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France. Electronic address: laurent.salomon@aphp.fr.
authors.forename: L
authors.initials: L
authors.lastname: Salomon
authors.affiliation: URC-Eco (unité de recherche clinique spécialisée en économie de la santé), Hôtel-Dieu, AP-HP, 1, place du Parvis-Notre-Dame, 75004 Paris, France.
authors.forename: I
authors.initials: I
authors.lastname: Durand-Zaleski
mesh_terms: D003362:Cost-Benefit Analysis; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000191:economics* / Q000628:therapy*
keywords: Aspects médico-économiques; Cancer de la prostate; Costs; Coûts; Medico-economic aspects; Prostate cancer; Prostatectomie totale; Public health; Radiothérapie; Santé publique