title: Peripheral Ulcerative Keratitis with Pyoderma Gangrenosum.
abstract: Pyoderma gangrenosum is an unusual necrotizing noninfective and ulcerative skin disease whose cause is unknown. Ophthalmic involvement in pyoderma gangrenosum is an unusual event. Only a few cases have been reported, from which we can highlight scleral, corneal, and orbital cases. Peripheral ulcerative keratitis is a process which destroys the peripheral cornea. Its cause is still unknown although it is often associated with autoimmune conditions. Pyoderma gangrenosum should be included in the differential diagnosis of peripheral ulcerative keratitis. Early recognition of these manifestations can vary the prognosis by applying the appropriate treatment. We introduce a 70-year-old woman who suffered pyoderma gangrenosum associated with peripheral ulcerative keratitis in her left eye. The patient's skin lesions and peripheral keratitis responded successfully to systemic steroids and cyclosporine A.
authors.affiliation: Department of Dermatology, Hospital Universitario Severo Ochoa, Avenida de Orellana, Leganés, 28911 Madrid, Spain.
authors.forename: Adrián
authors.initials: A
authors.lastname: Imbernón-Moya
authors.affiliation: Department of Dermatology, Hospital Universitario Severo Ochoa, Avenida de Orellana, Leganés, 28911 Madrid, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Vargas-Laguna
authors.affiliation: Department of Dermatology, Hospital Universitario Severo Ochoa, Avenida de Orellana, Leganés, 28911 Madrid, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Aguilar
authors.affiliation: Department of Dermatology, Hospital Universitario Severo Ochoa, Avenida de Orellana, Leganés, 28911 Madrid, Spain.
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Gallego
authors.affiliation: Department of Ophthalmology, Hospital Universitario Severo Ochoa, Avenida de Orellana, Leganés, 28911 Madrid, Spain.
authors.forename: Claudia
authors.initials: C
authors.lastname: Vergara
authors.affiliation: Department of Ophthalmology, Hospital Universitario Severo Ochoa, Avenida de Orellana, Leganés, 28911 Madrid, Spain.
authors.forename: María Fernanda
authors.initials: MF
authors.lastname: Nistal