title: [A MULTICENTER STUDY ON CHILDHOOD ALLERGIC RHINITIS TREATMENT IN THE TOHOKU REGION].
abstract: BACKGROUND
  We performed a multicenter study in order to clarify the present conditions of the childhood allergic rhinitis treatment in many departments of otorhinolaryngology and pediatrics/internal medicine in the Tohoku region, northern Japan.
  
  
  METHODS
  We performed a questionnaire survey about patient backgrounds, nasal symptoms, QOL disturbance, and treatment agents, for childhood allergic rhinitis patients under age 12.
  
  
  RESULTS
  The total number of cases was 814, the mean age of the patients seen in pediatrics/internal medicine departments was significantly lower than that in otorhinolaryngology. The merger rate of bronchial asthma of the patients seen in pediatrics/internal medicine was significantly higher, and nasal symptoms and QOL disturbance of the patients seen in otorhinolaryngology were significantly more severe. For therapeutic agents, antihistamines were most prescribed, and the combination of LT receptor antagonist and intranasal steroids was used for the cases in which nasal symptoms were severe. The nasal symptoms in the combination group were significantly improved compared with the antihistamine monotherapy group.
  
  
  CONCLUSIONS
  It was indicated that the combination therapy was useful in the severe cases of childhood allergic rhinitis.
authors.affiliation: Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Matsubara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ogawa
authors.forename: Nobuo
authors.initials: N
authors.lastname: Ohta
authors.forename: Takeshi
authors.initials: T
authors.lastname: Oshima
authors.forename: Kohei
authors.initials: K
authors.lastname: Honda
authors.forename: Morito
authors.initials: M
authors.lastname: Satoh
authors.forename: Yoko
authors.initials: Y
authors.lastname: Ichikawa
authors.forename: Yukitoshi
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Miki
authors.initials: M
authors.lastname: Morikawa
authors.forename: Masaki
authors.initials: M
authors.lastname: Komatsu
authors.forename: Shinichi
authors.initials: S
authors.lastname: Yoshida
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Tsuruta
authors.forename: Gen
authors.initials: G
authors.lastname: Tamura
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male; D011788:Quality of Life; D065631:Rhinitis, Allergic / Q000188:drug therapy* / Q000453:epidemiology; D011795:Surveys and Questionnaires
chemical_list: D006634:Histamine H1 Antagonists