title: Patients' Knowledge About Analgesic-Antipyretic Medications Purchased in Community Pharmacies: A Descriptive Study.
abstract: The objective of this study was to describe the level of knowledge about paracetamol (acetaminophen), ibuprofen, and aspirin of subjects who purchased nonprescription medications containing one of these drugs. We conducted this cross-sectional descriptive study in 42 community pharmacies located in southwestern France between July and November 2013. A six-item self-administered questionnaire was used. Participants were asked to identify the active ingredient contained in 14 brand-name analgesic-antipyretics, to state the maximum daily dose of paracetamol, ibuprofen, and aspirin, the recommended first-line analgesic, and precautions of use or contraindications for paracetamol, ibuprofen, and aspirin. Among 576 participants, the identification of paracetamol ranged from 58% (for Dafalgan or Efferalgan) to 90% (for Doliprane), the identification of ibuprofen from 34% (for Nureflex) to 63% (for Nurofen), and the identification of aspirin was 70% (for Aspegic). The maximum recommended daily dose of paracetamol, ibuprofen, and aspirin was known by 58.3%, 17.7%, and 19.3% of participants, respectively, whereas 6.8%, 17.2%, and 13.2% stated supratherapeutic daily doses. Paracetamol was correctly stated as the first-line analgesic-antipyretic by 76.2% of participants. Knowledge on major precautions of use or contraindications was poor (45.8% and 53.6% for ibuprofen and aspirin use during pregnancy, and 14.1% for concurrent use of anticoagulants and ibuprofen). Purchasers of nonprescription analgesic-antipyretics had poor knowledge on the medication they purchased.
authors.forename: Claire
authors.initials: C
authors.lastname: Grézy-Chabardès
authors.forename: Jean-Pascal
authors.initials: JP
authors.lastname: Fournier
authors.forename: Julie
authors.initials: J
authors.lastname: Dupouy
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Poutrain
authors.forename: Stéphane
authors.initials: S
authors.lastname: Oustric
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000737:chemistry*; D058633:Antipyretics / Q000008:administration & dosage / Q000737:chemistry*; D001241:Aspirin / Q000008:administration & dosage; D003157:Community Pharmacy Services; D000075202:Contraindications; D005260:Female; D005602:France; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D004366:Nonprescription Drugs / Q000008:administration & dosage / Q000737:chemistry; D055815:Young Adult
chemical_list: D018712:Analgesics, Non-Narcotic; D058633:Antipyretics; D004366:Nonprescription Drugs; D000082:Acetaminophen; D001241:Aspirin; D007052:Ibuprofen
keywords: analgesics; antipyretics; nonprescription drugs; patient medication knowledge; patient safety; primary care