title: Guaiasistanol: A new guaiane sesquiterpenoid from Teucrium persicum Boiss.
abstract: In this study, a new guaiane type skeleton sesquiterpenoid named guaiasistanol (6α, 10α-epoxy-4α-hydroxyguaiane) was isolated from chloroform part of the Teucrium persicum extract, also chrysothol. Spectroscopic means explained the structures. This compound was evaluated for inhibitory activity against acetylcholinesterase and it showed a moderate activity with 28% inhibition.
authors.affiliation: Zabol University of Medical Sciences Zabol Medicinal Plants Research Center Zabol Iran.
authors.forename: A
authors.initials: A
authors.lastname: Miri
authors.affiliation: Zabol University of Medical Sciences Zabol Medicinal Plants Research Center Zabol Iran javad.sharifirad&commat;gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Sharifi-Rad
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism*; D002800:Cholinesterase Inhibitors / Q000032:analysis / Q000737:chemistry* / Q000494:pharmacology; D007492:Iran; D009682:Magnetic Resonance Spectroscopy; D008519:Medicine, Traditional; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry* / Q000494:pharmacology; D045789:Sesquiterpenes, Guaiane / Q000032:analysis / Q000737:chemistry* / Q000494:pharmacology*; D031367:Teucrium / Q000737:chemistry / Q000378:metabolism*
chemical_list: D002800:Cholinesterase Inhibitors; D010936:Plant Extracts; D045789:Sesquiterpenes, Guaiane; C040618:teucrium extract; D000110:Acetylcholinesterase