title: Evaluation of obstetrical patients with disseminated intravascular coagulopathy - tertiary center experience.
abstract: OBJECTIVE
  The purpose of the present study is twofold: (a) to investigate the etiology of disseminated intravascular coagulopathy (DIC) caused by obstetrical conditions and (b) to present parameters that can be used in predicting DIC-related mortality in obstetrical patients.
  
  
  METHODS
  Obstetrical patients who had a delivery at or were referred (after delivery) to Obstetrics and Gynecology Clinic of Dicle University between July 2006 and December 2013 were retrospectively analyzed in this study. Those patients diagnosed with DIC were included in the study.
  
  
  RESULTS
  Fifty-six obstetrical patients carrying the diagnosis of DIC were included in this study. The overall mortality rate was 25% among these patients. More specifically, the mortality rate was 10.7% among patients with a DIC score ≤5 and 40.7% among those with a DIC score > 5. Multiple logistic regression analysis resulted in the finding that international normalized ratio (INR) and urea were among those factors affecting mortality in obstetrical DIC [OR: 8.44 (CI: 1.9-36.8), OR: 1.05 (CI: 1.0-1.1), respectively].
  
  
  CONCLUSIONS
  DIC is a syndrome that might be caused by obstetrical conditions. It is associated with high mortality and morbidity rates. In obstetrical DIC, urea is the most important factor affecting mortality. In addition, we are of the opinion that DIC score might guide mortality predictions as a determinant of prognosis.
authors.affiliation: a Department of Obstetrics and Gynecology , School of Medicine, Fatih University , Istanbul , Turkey .
authors.forename: Serdar
authors.initials: S
authors.lastname: Başaranoğlu
authors.affiliation: b Department of Obstetrics and Gynecology , School of Medicine, Dicle University , Diyarbakir , Turkey .
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sıddık Evsen
authors.affiliation: b Department of Obstetrics and Gynecology , School of Medicine, Dicle University , Diyarbakir , Turkey .
authors.forename: Elif
authors.initials: E
authors.lastname: Ağaçayak
authors.affiliation: b Department of Obstetrics and Gynecology , School of Medicine, Dicle University , Diyarbakir , Turkey .
authors.forename: Senem Yaman
authors.initials: SY
authors.lastname: Tunç
authors.affiliation: c Department of Nephrology , School of Medicine, Dicle University , Diyarbakir , Turkey , and.
authors.forename: Zülfikar
authors.initials: Z
authors.lastname: Yılmaz
authors.affiliation: c Department of Nephrology , School of Medicine, Dicle University , Diyarbakir , Turkey , and.
authors.forename: Yaşar
authors.initials: Y
authors.lastname: Yıldırım
authors.affiliation: a Department of Obstetrics and Gynecology , School of Medicine, Fatih University , Istanbul , Turkey .
authors.forename: Avşeqüi
authors.initials: A
authors.lastname: Deregözü
authors.affiliation: b Department of Obstetrics and Gynecology , School of Medicine, Dicle University , Diyarbakir , Turkey .
authors.forename: Muhammet Erdal
authors.initials: ME
authors.lastname: Sak
authors.affiliation: d Department of Anesthesiology , School of Medicine, Dicle University , Diyarbakir , Turkey.
authors.forename: Zeynep Baysal
authors.initials: ZB
authors.lastname: Yıldırım
authors.affiliation: d Department of Anesthesiology , School of Medicine, Dicle University , Diyarbakir , Turkey.
authors.forename: Gönül Ölmez
authors.initials: GÖ
authors.lastname: Kavak
authors.affiliation: b Department of Obstetrics and Gynecology , School of Medicine, Dicle University , Diyarbakir , Turkey .
authors.forename: Talip
authors.initials: T
authors.lastname: Gül
mesh_terms: D000328:Adult; D036861:Delivery, Obstetric / Q000379:methods; D004211:Disseminated Intravascular Coagulation / Q000145:classification / Q000209:etiology* / Q000401:mortality*; D005260:Female; D006801:Humans; D015994:Incidence; D019934:International Normalized Ratio; D016015:Logistic Models; D008428:Maternal Mortality; D049590:Postpartum Period / Q000097:blood; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000145:classification / Q000209:etiology* / Q000401:mortality*; D012189:Retrospective Studies; D012307:Risk Factors; D062606:Tertiary Care Centers; D014508:Urea
chemical_list: D014508:Urea
keywords: Diagnosis; disseminated intravascular coagulopathy; obstetrical bleeding; relaparotomy; treatment