title: Moderate alcohol intake reduces risk of ischemic stroke in Korea.
abstract: OBJECTIVE
  We undertook a population-based, case-control study to examine a dose-response relationship between alcohol intake and risk of ischemic stroke in Koreans who had different alcoholic beverage type preferences than Western populations and to examine the effect modifications by sex and ischemic stroke subtypes.
  
  
  METHODS
  Cases (n = 1,848) were recruited from patients aged 20 years or older with first-ever ischemic stroke. Stroke-free controls (n = 3,589) were from the fourth and fifth Korean National Health and Nutrition Examination Survey and were matched to the cases by age (±3 years), sex, and education level. All participants completed an interview using a structured questionnaire about alcohol intake.
  
  
  RESULTS
  Light to moderate alcohol intake, 3 or 4 drinks (1 drink = 10 g ethanol) per day, was significantly associated with a lower odds of ischemic stroke after adjusting for potential confounders (no drinks: reference; <1 drink: odds ratio 0.38, 95% confidence interval 0.32-0.45; 1-2 drinks: 0.45, 0.36-0.57; and 3-4 drinks: 0.54, 0.39-0.74). The threshold of alcohol effect in women was slightly lower than that in men (up to 1-2 drinks in women vs up to 3-4 drinks in men), but this difference was not statistically significant. There was no statistical interaction between alcohol intake and the subtypes of ischemic stroke (p = 0.50). The most frequently used alcoholic beverage was one native to Korea, soju (78% of the cases), a distilled beverage with 20% ethanol by volume.
  
  
  CONCLUSIONS
  Our findings suggest that light to moderate distilled alcohol consumption may reduce the risk of ischemic stroke in Koreans.
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Soo Joo
authors.initials: SJ
authors.lastname: Lee
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Yong-Jin
authors.initials: YJ
authors.lastname: Cho
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Jae Guk
authors.initials: JG
authors.lastname: Kim
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Youngchai
authors.initials: Y
authors.lastname: Ko
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Keun-Sik
authors.initials: KS
authors.lastname: Hong
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Jong-Moo
authors.initials: JM
authors.lastname: Park
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Kyusik
authors.initials: K
authors.lastname: Kang
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Tai Hwan
authors.initials: TH
authors.lastname: Park
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Sang-Soon
authors.initials: SS
authors.lastname: Park
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Kyung Bok
authors.initials: KB
authors.lastname: Lee
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Jae Kwan
authors.initials: JK
authors.lastname: Cha
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Dae-Hyun
authors.initials: DH
authors.lastname: Kim
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Jun
authors.initials: J
authors.lastname: Lee
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Joon-Tae
authors.initials: JT
authors.lastname: Kim
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Juneyoung
authors.initials: J
authors.lastname: Lee
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Ji Sung
authors.initials: JS
authors.lastname: Lee
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Myung Suk
authors.initials: MS
authors.lastname: Jang
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Moon-Ku
authors.initials: MK
authors.lastname: Han
authors.affiliation: From the Department of Neurology (S.J.L., J.G.K., Y.K.), Eulji University Hospital, Daejeon; Department of Neurology (Y.-J.C., K.-S.H.), Inje University Ilsan Paik Hospital, Goyang-si, Gyeonggi-do; Department of Neurology (J.-M.P., K.K.), Eulji General Hospital, Seoul; Department of Neurology (T.H.P., S.-S.P.), Seoul Medical Center; Department of Neurology (K.B.L.), Soonchunhyang University Hospital Seoul; Department of Neurology (J.K.C., D.-H.K.), Dong-A University Hospital, Busan; Department of Neurology (Jun Lee), Yeungnam University Medical Center, Daegu; Department of Neurology (J.-T.K.), Chonnam National University Hospital, Gwangju; Department of Biostatistics (Juneyoung Lee), Korea University College of Medicine, Seoul; Clinical Research Center (J.S.L.), Asan Medical Center, Seoul; Department of Neurology and Cerebrovascular Center (M.S.J., M.-K.H., H.-J.B.), Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea; and Department of Translational Science & Molecular Medicine (P.B.G.), Michigan State University College of Human Medicine and Medical Director, Mercy Health Hauenstein Neurosciences, Grand Rapids, MI.
authors.forename: Philip B
authors.initials: PB
authors.lastname: Gorelick
authors.forename: Hee-Joon
authors.initials: HJ
authors.lastname: Bae
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000453:epidemiology*; D002545:Brain Ischemia / Q000453:epidemiology*; D016022:Case-Control Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D056910:Republic of Korea; D012306:Risk; D020521:Stroke / Q000453:epidemiology*; D055815:Young Adult