title: Numb chin syndrome as a manifestation of jaw metastasis diagnosed in a bone scan.
abstract: In many cases, numb chin syndrome (NCS) may represent a banal pathology. However, as it can be associated with malignant processes, its presence should alert the clinician of a possible occult disease. In patients already diagnosed with cancer, it often represents an ominous sign that indicates poor prognosis, due to the rapid progress of the disease. The case is presented of a 62-year-old man diagnosed with synchronous lung and bladder cancer, who suddenly complained of numbness in the chin. The bone scan confirmed the suspicion of metastastic bone disease, and the patient died two months after the appearance of this sign.
authors.affiliation: Servei de Medicina Nuclear, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, España. Electronic address: edelnoriega@gmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Noriega
authors.affiliation: Servei de Medicina Nuclear, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Sabaté-Llobera
authors.affiliation: Servei de Medicina Nuclear, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Benítez
authors.affiliation: Servei de Medicina Nuclear, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, España.
authors.forename: G A
authors.initials: GA
authors.lastname: Martínez
authors.affiliation: Servei de Medicina Nuclear, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Rodríguez-Rubio
authors.affiliation: Servei de Medicina Nuclear, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Mora
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D002277:Carcinoma / Q000150:complications / Q000000981:diagnostic imaging / Q000556:secondary*; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging / Q000473:pathology; D002680:Chin / Q000294:innervation; D017809:Fatal Outcome; D006801:Humans; D006987:Hypesthesia / Q000209:etiology*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008339:Mandibular Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000556:secondary*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals / Q000032:analysis; D000072098:Single Photon Emission Computed Tomography Computed Tomography; D013577:Syndrome; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives / Q000032:analysis; D014057:Tomography, X-Ray Computed; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D019275:Radiopharmaceuticals; C024226:technetium Tc 99m hydroxymethylene diphosphonate; D013669:Technetium Tc 99m Medronate
keywords: Bone scan; Facial numbness; Gammagrafía ósea; Hipoestesia; Hypoaesthesia; Mandibular metastasis; Mentón entumecido; Metástasis mandibular; Numb chin syndrome; SPECT/CT; SPECT/TC; Signo de Roger