title: Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom.
abstract: OBJECTIVE
  To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome.
  
  
  METHODS
  A retrospective study was conducted with patients with temporal low-grade gliomas (LGG).
  
  
  RESULTS
  Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection.
  
  
  CONCLUSIONS
  Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom.
authors.affiliation: Departamento de Ciências Neurológica, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Lucas Crociati
authors.initials: LC
authors.lastname: Meguins
authors.affiliation: Departamento de Ciências Neurológica, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Rodrigo Antônio Rocha da Cruz
authors.initials: RA
authors.lastname: Adry
authors.affiliation: Departamento de Ciências Neurológica, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Sebastião Carlos da
authors.initials: SC
authors.lastname: Silva Júnior
authors.affiliation: Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Carlos Umberto
authors.initials: CU
authors.lastname: Pereira
authors.affiliation: Departamento de Ciências Medicas, Faculdade de Medicina, Universidade Nove de Julho, São Paulo, SP, Brazil.
authors.forename: Jean Gonçalves de
authors.initials: JG
authors.lastname: Oliveira
authors.affiliation: Departamento de Ciências Neurológica, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Dionei Freitas de
authors.initials: DF
authors.lastname: Morais
authors.affiliation: Departamento de Psiquiatria e Medicina Psicológica, Faculdade de Medicina de São José do Rio Preto, São Paulo, SP, Brazil.
authors.forename: Gerardo Maria de
authors.initials: GM
authors.lastname: Araújo Filho
authors.affiliation: Departamento de Ciências Neurológica, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Lúcia Helena Neves
authors.initials: LH
authors.lastname: Marques
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D002648:Child; D000069279:Drug Resistant Epilepsy / Q000209:etiology / Q000517:prevention & control / Q000601:surgery*; D004569:Electroencephalography; D005260:Female; D005910:Glioma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology / Q000517:prevention & control / Q000601:surgery*; D013702:Temporal Lobe / Q000473:pathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult