title: Prevalence and clinical characteristics of adrenal incidentalomas in potential kidney donors.
abstract: BACKGROUND
  The prevalence of adrenal incidentalomas (AIs) in asymptomatic individuals is unknown. This study evaluated the prevalence of AIs in healthy kidney donors in whom pre-operative computed tomography (CT) is performed routinely.
  
  
  METHODS
  All potential kidney donors evaluated at the Rabin Medical Center who had routine abdominal CT were identified and their medical records were retrospectively reviewed. Subjects who had normal CT scans were compared with those with a finding of an AI, evaluating demographic (age, body mass index, systolic and diastolic blood pressure) and laboratory variables (glucose, sodium, potassium, calcium, phosphorus, albumin and creatinine). In addition, prevalence of hypertension, rate of donation and surgical mortality were compared between the two groups.
  
  
  RESULTS
  CT was performed in 673 potential kidney donors. Of these, 645 had a normal CT and 28 (4.2%) had evidence of an AI. Those with AIs had a similar prevalence of hypertension, kidney donation and surgical mortality as those with a normal CT. Those with AIs were older (50.93 ± 11.1 versus 43.76 ± 11.1 years) but other demographic variables were similar; laboratory variables were also similar except for slightly lower albumin and creatinine in those with AIs.
  
  
  CONCLUSIONS
  The prevalence of AIs is high even in healthy asymptomatic individuals.
authors.affiliation: a Endocrinology and Metabolism Unit , Rabin Medical Center , Petah Tikva , Israel.|b Sackler Faculty of Medicine , Tel Aviv University.
authors.forename: Alon
authors.initials: A
authors.lastname: Grossman
authors.affiliation: a Endocrinology and Metabolism Unit , Rabin Medical Center , Petah Tikva , Israel.|b Sackler Faculty of Medicine , Tel Aviv University.
authors.forename: Ronit
authors.initials: R
authors.lastname: Koren
authors.affiliation: a Endocrinology and Metabolism Unit , Rabin Medical Center , Petah Tikva , Israel.|b Sackler Faculty of Medicine , Tel Aviv University.
authors.forename: Amit
authors.initials: A
authors.lastname: Tirosh
authors.affiliation: b Sackler Faculty of Medicine , Tel Aviv University.|c Department of Transplantation , Rabin Medical Center, Beilinson Campus , Israel.
authors.forename: Rachel
authors.initials: R
authors.lastname: Michowiz
authors.affiliation: d Bio-Statistical Unit , Rabin Medical Center, Beilinson Campus , Israel.
authors.forename: Zippora
authors.initials: Z
authors.lastname: Shohat
authors.affiliation: b Sackler Faculty of Medicine , Tel Aviv University.|c Department of Transplantation , Rabin Medical Center, Beilinson Campus , Israel.
authors.forename: Ruth
authors.initials: R
authors.lastname: Rahamimov
authors.affiliation: b Sackler Faculty of Medicine , Tel Aviv University.|c Department of Transplantation , Rabin Medical Center, Beilinson Campus , Israel.
authors.forename: Eytan
authors.initials: E
authors.lastname: Mor
authors.affiliation: a Endocrinology and Metabolism Unit , Rabin Medical Center , Petah Tikva , Israel.|b Sackler Faculty of Medicine , Tel Aviv University.
authors.forename: Ilan
authors.initials: I
authors.lastname: Shimon
authors.affiliation: a Endocrinology and Metabolism Unit , Rabin Medical Center , Petah Tikva , Israel.|b Sackler Faculty of Medicine , Tel Aviv University.
authors.forename: Eyal
authors.initials: E
authors.lastname: Robenshtok
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000453:epidemiology*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000706:statistics & numerical data*; D019520:Living Donors / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D015995:Prevalence; D055815:Young Adult
keywords: Adrenal; incidentaloma; kidney donors