title: FDG-PET/CT for Detection of Extramedullary Disease in 2 Pediatric Patients With AML.
abstract: Positron emission tomography combined with computed tomography (PET/CT) is a promising diagnostic procedure for the detection of extramedullary disease (EMD) in acute myeloid leukemia. We studied 2 children with acute myeloid leukemia who underwent PET to assess for EMD at diagnosis as well as in remission. We detected 5 EMD lesions in 2 cases with PET, only 2 of which were detectable on clinical examination. Our cases show PET's increased sensitivity over physical examination alone in assessing and monitoring the extent of this disease.
authors.affiliation: Departments of *Pediatrics †Radiology, Division of Nuclear Medicine, National Center for Global Health and Medicine, Tokyo, Japan.
authors.forename: Motohiro
authors.initials: M
authors.lastname: Matsui
authors.forename: Junko
authors.initials: J
authors.lastname: Yamanaka
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Shichino
authors.forename: Noriko
authors.initials: N
authors.lastname: Sato
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kubota
authors.forename: Takeji
authors.initials: T
authors.lastname: Matsushita
mesh_terms: D002648:Child; D002968:Clavicle / Q000000981:diagnostic imaging / Q000473:pathology; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007223:Infant; D015470:Leukemia, Myeloid, Acute / Q000000981:diagnostic imaging*; D008297:Male; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D023981:Sarcoma, Myeloid / Q000000981:diagnostic imaging*
chemical_list: D019788:Fluorodeoxyglucose F18