title: Death domain associated protein (Daxx), a multi-functional protein.
abstract: Death domain associated protein (Daxx), a multi-functional protein, plays an important role in transcriptional regulation, cell apoptosis, carcinogenesis, anti-virus infection and so on. However, its regulatory mechanisms for both cell survival and apoptosis remain largely obscure. Our review of recent studies shows that Daxx has many interesting functional dualities and can provide a reference for further research on Daxx.
authors.forename: Shuang-Yang
authors.initials: SY
authors.lastname: Tang
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Wan
authors.forename: Yi-Mou
authors.initials: YM
authors.lastname: Wu
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002843:Chromatin / Q000378:metabolism; D056970:Co-Repressor Proteins; D004265:DNA Helicases / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D018832:Molecular Chaperones; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D025841:Small Ubiquitin-Related Modifier Proteins / Q000378:metabolism; D019098:Telomerase / Q000378:metabolism; D000075924:X-linked Nuclear Protein
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D002843:Chromatin; D056970:Co-Repressor Proteins; C106985:DAXX protein, human; D018832:Molecular Chaperones; D009687:Nuclear Proteins; D025841:Small Ubiquitin-Related Modifier Proteins; D019098:Telomerase; D004265:DNA Helicases; C092332:ATRX protein, human; D000075924:X-linked Nuclear Protein