title: Low miR-19b-1-5p expression in isolated platelets after aspirin use is related to aspirin insensitivity.
authors.affiliation: Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Experimental Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: M G M
authors.initials: MG
authors.lastname: Kok
authors.affiliation: Department of Experimental Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Hypertension and Dyslipidemia, Geriatric Clinic and European Center on Atherosclerosis, G. D'Annunzio University, Chieti, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Mandolini
authors.affiliation: Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: P D
authors.initials: PD
authors.lastname: Moerland
authors.affiliation: Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Experimental Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: M W J
authors.initials: MW
authors.lastname: de Ronde
authors.affiliation: Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: B M
authors.initials: BM
authors.lastname: Sondermeijer
authors.affiliation: Department of Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Halliani
authors.affiliation: Department of Clinical Chemistry, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: Nieuwland
authors.affiliation: Department of Hypertension and Dyslipidemia, Geriatric Clinic and European Center on Atherosclerosis, G. D'Annunzio University, Chieti, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Cipollone
authors.affiliation: Department of Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: E E
authors.initials: EE
authors.lastname: Creemers
authors.affiliation: Department of Experimental Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Plasma Proteins, Sanquin, Amsterdam, The Netherlands.
authors.forename: J C M
authors.initials: JC
authors.lastname: Meijers
authors.affiliation: Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: S.J.Pinto@amc.uva.nl.
authors.forename: S J
authors.initials: SJ
authors.lastname: Pinto-Sietsma
mesh_terms: D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D000924:Anticholesteremic Agents / Q000008:administration & dosage; D001241:Aspirin / Q000008:administration & dosage*; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D003324:Coronary Artery Disease / Q000097:blood / Q000188:drug therapy / Q000235:genetics; D004351:Drug Resistance; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage; D008297:Male; D035683:MicroRNAs / Q000096:biosynthesis / Q000097:blood* / Q000235:genetics; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D012313:RNA / Q000097:blood / Q000235:genetics; D019821:Simvastatin / Q000008:administration & dosage
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000924:Anticholesteremic Agents; C549214:MIRN19A microRNA, human; D035683:MicroRNAs; D010975:Platelet Aggregation Inhibitors; D012313:RNA; D019821:Simvastatin; D001241:Aspirin; D007213:Indomethacin
keywords: Antiplatelet agents; Aspirin resistance; Prevention; miRNA