title: Disseminated mucormycosis with myocardial involvement in a renal transplant recipient.
abstract: We report the case of a renal transplant recipient with pulmonary and splenic mucormycosis whose demise was accelerated by a myocardial abscess. Once pulmonary and splenic mucormycosis was diagnosed, liposomal amphotericin B was started and immunosuppressant treatments were discontinued. The pulmonary cavities regressed during treatment, but new myocardial and peri-allograft abscesses developed. The myocardial abscess diffusely infiltrated the left ventricular wall and was associated with akinesia, which led to sudden cardiac arrest. This case demonstrates a rare manifestation of mucormycosis and highlights the fatality and invasiveness of this infection.
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.
authors.forename: Y
authors.initials: Y
authors.lastname: Nam
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.
authors.forename: J
authors.initials: J
authors.lastname: Jung
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.
authors.forename: S S
authors.initials: SS
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.|Division of Nephrology, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea.
authors.forename: S J
authors.initials: SJ
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.|Division of Nephrology, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea.
authors.forename: S J
authors.initials: SJ
authors.lastname: Shin
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.|Division of Infectious Disease, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.|Division of Cardiology, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea.
authors.forename: M
authors.initials: M
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Incheon, Korea.|Division of Nephrology, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea.
authors.forename: H E
authors.initials: HE
authors.lastname: Yoon
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006331:Heart Diseases / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000009:adverse effects*; D009091:Mucormycosis / Q000188:drug therapy / Q000473:pathology*; D009206:Myocardium
chemical_list: D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B
keywords: mucormycosis; myocardial abscess; renal transplantation