title: Sensitive electrochemical nonenzymatic glucose sensing based on anodized CuO nanowires on three-dimensional porous copper foam.
abstract: In this work, we proposed to utilize three-dimensional porous copper foam (CF) as conductive substrate and precursor of in-situ growth CuO nanowires (NWs) for fabricating electrochemical nonenzymatic glucose sensors. The CF supplied high surface area due to its unique three-dimensional porous foam structure, and thus resulted in high sensitivity for glucose detection. The CuO NWs/CF based nonenzymatic sensors presented reliable selectivity, good repeatability, reproducibility, and stability. In addition, the CuO NWs/CF based nonenzymatic sensors have been employed for practical applications, and the glucose concentration in human serum was measured to be 4.96 ± 0.06 mM, agreed well with the value measured from the commercial available glucose sensor in hospital, and the glucose concentration in saliva was also estimated to be 0.91 ± 0.04 mM, which indicated that the CuO NWs/CF owned the possibility for noninvasive glucose detection. The rational design of CuO NWs/CF provided an efficient strategy for fabricating of electrochemical nonenzymatic biosensors.
authors.affiliation: School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
authors.forename: Zhenzhen
authors.initials: Z
authors.lastname: Li
authors.affiliation: School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.affiliation: School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
authors.forename: Yanmei
authors.initials: Y
authors.lastname: Xin
authors.affiliation: School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
authors.forename: Zhonghai
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D003300:Copper / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000379:methods; D004563:Electrochemistry / Q000379:methods; D004566:Electrodes; D005947:Glucose / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D053770:Nanowires / Q000737:chemistry*; D010084:Oxidation-Reduction; D016062:Porosity; D015203:Reproducibility of Results; D012463:Saliva / Q000737:chemistry; D044967:Serum / Q000737:chemistry
chemical_list: D003300:Copper; D005947:Glucose