title: Atypical Fast-Slow Atrioventricular Nodal Reentrant Tachycardia Incorporating a "Superior" Slow Pathway: A Distinct Supraventricular Tachyarrhythmia.
abstract: BACKGROUND
  The existence of an atypical fast-slow (F/S) atrioventricular nodal reentrant tachycardia (AVNRT) including a superior (sup) pathway with slow conductive properties and an atrial exit near the His bundle has not been confirmed.
  
  
  RESULTS
  We studied 6 women and 2 men (age, 74 ± 7 years) with sup-F/S-AVNRT who underwent successful radiofrequency ablation near the His bundle. Programmed ventricular stimulation induced retrograde conduction over a superior SP with an earliest atrial activation near the His bundle, a mean shortest spike-atrial interval of 378 ± 119 milliseconds, and decremental properties in all patients. sup-F/S-AVNRT was characterized by a long-RP interval; a retrograde atrial activation sequence during tachycardia identical to that over a sup-SP during ventricular pacing; ventriculoatrial dissociation during ventricular overdrive pacing of the tachycardia in 5 patients or atrioventricular block occurring during tachycardia in 3 patients, excluding atrioventricular reentrant tachycardia; termination of the tachycardia by ATP; and a V-A-V activation sequence immediately after ventricular induction or entrainment of the tachycardia, including dual atrial responses in 2 patients. Elimination or modification of retrograde conduction over the sup-SP by ablation near the right perinodal region or from the noncoronary cusp of Valsalva eliminated and confirmed the diagnosis of AVNRT in 4 patients each.
  
  
  CONCLUSIONS
  sup-F/S-AVNRT is a distinct supraventricular tachycardia, incorporating an SP located above the Koch triangle as the retrograde limb, that can be eliminated by radiofrequency ablation.
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.). kanekoy@gunma-u.ac.jp.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kaneko
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Shigeto
authors.initials: S
authors.lastname: Naito
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Kaoru
authors.initials: K
authors.lastname: Okishige
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Itsuro
authors.initials: I
authors.lastname: Morishima
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tobiume
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Tadashi
authors.initials: T
authors.lastname: Nakajima
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Tadanobu
authors.initials: T
authors.lastname: Irie
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Masaki
authors.initials: M
authors.lastname: Ota
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Takafumi
authors.initials: T
authors.lastname: Iijima
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Takashi
authors.initials: T
authors.lastname: Iizuka
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Mio
authors.initials: M
authors.lastname: Tamura
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Shuntaro
authors.initials: S
authors.lastname: Tamura
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Akihiro
authors.initials: A
authors.lastname: Saito
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Osamu
authors.initials: O
authors.lastname: Igawa
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Ritsushi
authors.initials: R
authors.lastname: Kato
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Kazuo
authors.initials: K
authors.lastname: Matsumoto
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Fumio
authors.initials: F
authors.lastname: Suzuki
authors.affiliation: From Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (Y.K., T.N., T.I., M.O., T.I., T.I., M.T., S.T., A.S., M.K.); Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan (S.N.); Heart Center, Yokohama-City Bay Red Cross Hospital, Japan (K.O.); Department of Cardiology, Ogaki Municipal Hospital, Gifu, Japan (I.M.); Department of Cardiology, Tokushima University, Japan (T.T.); Division of Cardiology, International Medical Center, Saitama Medical University, Hidaka, Japan (T.T., R.K., K.M.); Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan (O.I.); and Department of Cardiology, Fukujuji Hospital, Kiyose, Tokyo, Japan (F.S.).
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kurabayashi
mesh_terms: D000255:Adenosine Triphosphate / Q000494:pharmacology; D000359:Aftercare; D000368:Aged; D000369:Aged, 80 and over; D001283:Atrioventricular Node / Q000503:physiopathology; D002036:Bundle of His / Q000503:physiopathology; D006328:Cardiac Catheterization; D002304:Cardiac Pacing, Artificial; D017115:Catheter Ablation; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D013617:Tachycardia, Supraventricular / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery
chemical_list: D000255:Adenosine Triphosphate; D007545:Isoproterenol
keywords: ablation techniques; arrhythmias, cardiac; atrioventricular node; electrophysiology; tachycardia