title: Trends in Nanomaterials and Processing for Drug Delivery of Polyphenols in the Treatment of Cancer and Other Therapies.
abstract: For decades polyphenols have been considered to be sound, naturally occurring therapeutic compounds. While there are several polyphenols with special applications used in the treatment of cancer and other diseases, they need a specific carrier in order to reach the cells targeted for treatment. Recently, a number of new technologies have been developed on a nanoscale, such as nanoparticles, nanocapsules and nanofibers that can provide targeted delivery of polyphenols for medical purposes. This work summarizes the current trends in nanoscale delivery technology for polyphenols in cancer treatment and outlines its capabilities and the significant improvements that have been made. Special emphasis is given to the materials and to the manufacturing processes used to produce these kinds of drug delivery system nanostructures.
authors.affiliation: Department of Mechanical Engineering and Civil Construction, Universitat de Girona, C/ Maria Aurèlia Capmany, 61, 17003 Girona, Spain.
authors.forename: Joaquim
authors.initials: J
authors.lastname: Ciurana
authors.forename: Ciro A
authors.initials: CA
authors.lastname: Rodríguez
mesh_terms: D004339:Drug Compounding; D016503:Drug Delivery Systems; D006801:Humans; D049329:Nanostructures / Q000737:chemistry; D009369:Neoplasms / Q000188:drug therapy*; D059808:Polyphenols / Q000627:therapeutic use*
chemical_list: D059808:Polyphenols
keywords: Drug deliver; nanocapsules; nanofibers.; polyphenols