title: Prevent and Cure: RPA Cooperates with Mre11-Sae2 in DNA Secondary Structure Repair.
abstract: DNA inversion duplications are genome rearrangements observed in cancer. In this issue, Deng et al. (2015) demonstrate that in S. cerevisiae RPA and Mre11-Sae2 cooperate to prevent the formation of inversion duplications initiated at short DNA secondary structures.
authors.affiliation: The Institute of Cell Biology, School of Biological Sciences, The University of Edinburgh, Edinburgh EH9 3FF, UK. Electronic address: d.leach@ed.ac.uk.
authors.forename: David R F
authors.initials: DR
authors.lastname: Leach
mesh_terms: D004706:Endodeoxyribonucleases / Q000378:metabolism*; D004720:Endonucleases / Q000378:metabolism*; D005090:Exodeoxyribonucleases / Q000378:metabolism*; D005784:Gene Amplification; D055029:Inverted Repeat Sequences; D051716:Replication Protein A / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*
chemical_list: D051716:Replication Protein A; D029701:Saccharomyces cerevisiae Proteins; D004706:Endodeoxyribonucleases; D004720:Endonucleases; D005090:Exodeoxyribonucleases