title: Diagnosis of prostate cancer via nanotechnological approach.
abstract: Prostate cancer is one of the leading causes of cancer-related deaths among the Caucasian adult males in Europe and the USA. Currently available diagnostic strategies for patients with prostate cancer are invasive and unpleasant and have poor accuracy. Many patients have been overly or underly treated resulting in a controversy regarding the reliability of current conventional diagnostic approaches. This review discusses the state-of-the-art research in the development of novel noninvasive prostate cancer diagnostics using nanotechnology coupled with suggested diagnostic strategies for their clinical implication.
authors.affiliation: KIST Biomedical Research Institute, Korea University of Science and Technology (UST), Seoul, Republic of Korea ; Department of Biomedical Engineering, Korea University of Science and Technology (UST), Seoul, Republic of Korea.
authors.forename: Benedict J
authors.initials: BJ
authors.lastname: Kang
authors.affiliation: KIST Biomedical Research Institute, Korea University of Science and Technology (UST), Seoul, Republic of Korea ; Department of Biomedical Engineering, Korea University of Science and Technology (UST), Seoul, Republic of Korea.
authors.forename: Minhong
authors.initials: M
authors.lastname: Jeun
authors.affiliation: KIST Biomedical Research Institute, Korea University of Science and Technology (UST), Seoul, Republic of Korea ; Department of Biomedical Engineering, Korea University of Science and Technology (UST), Seoul, Republic of Korea.
authors.forename: Gun Hyuk
authors.initials: GH
authors.lastname: Jang
authors.affiliation: Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Song
authors.affiliation: Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors.forename: In Gab
authors.initials: IG
authors.lastname: Jeong
authors.affiliation: Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors.forename: Choung-Soo
authors.initials: CS
authors.lastname: Kim
authors.affiliation: Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Peter C
authors.initials: PC
authors.lastname: Searson
authors.affiliation: KIST Biomedical Research Institute, Korea University of Science and Technology (UST), Seoul, Republic of Korea ; Department of Biomedical Engineering, Korea University of Science and Technology (UST), Seoul, Republic of Korea.
authors.forename: Kwan Hyi
authors.initials: KH
authors.lastname: Lee
mesh_terms: D001681:Biological Assay; D001826:Body Fluids / Q000378:metabolism; D006801:Humans; D008297:Male; D050997:Nanomedicine / Q000295:instrumentation / Q000379:methods*; D017430:Prostate-Specific Antigen / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D017430:Prostate-Specific Antigen
keywords: PSA; bioassay; bodily fluid; nanodevice; nanomaterial; non-PSA biomarker