title: Cytoreductive Surgery and HIPEC in the Baltic States: An International Scientific Workshop with Live Surgery.
abstract: BACKGROUND
  Around the globe a new interest in the multidisciplinary management of peritoneal metastases using neoadjuvant chemotherapy, cytoreductive surgery (CRS), hyperthermic intraperitoneal chemotherapy (HIPEC), and adjuvant systemic chemotherapy has occurred. The combined use of these treatment modalities has required the creation of centers of excellence to manage patients with peritoneal metastases with a high level of success as well as a low incidence of adverse events.
  
  
  METHODS
  A 2-day workshop hosted by the Center of Abdominal Surgery, Vilnius University Hospital, with 230 participants was organized to explore the current practice in the Baltic states. Live surgery with video transmission initiated the efforts. Then, presentations by five experts from high-volume peritoneal surface malignancy centers were made and discussed. A summary of the efforts to date in Lithuania and Estonia was presented and collected for publication.
  
  
  RESULTS
  The live surgery served as a focal point for all subsequent presentations. The five invited speakers reviewed the rationale, current literature, indications and contraindications, implementation, and current European guidelines for management. The results of CRS and HIPEC from five centers in Lithuania and Estonia currently active revealed 127 patients treated to date, half of whom carried a diagnosis of ovarian cancer. There was an incidence of major complications of 11.8% and a mortality of 1.6%. Data regarding long-term survival benefits will require further follow-up.
  
  
  CONCLUSIONS
  Progress in peritoneal surface oncology in the Baltic states was confirmed. With a low morbidity and mortality, these clinical programs promise to provide continued benefit for patients with peritoneal metastases - a condition judged to be terminal in the past.
authors.affiliation: Center of Abdominal Surgery, Vilnius University Hospital, Vilnius, Lithuania.
authors.forename: Eligijus
authors.initials: E
authors.lastname: Poskus
authors.affiliation: Clinic of Gastroenterology, Nephrourology and Surgery, Center of Abdominal Surgery, Faculty of Medicine, Vilnius University, Santariskiu Clinics, Vilnius, Lithuania.
authors.forename: Kestutis
authors.initials: K
authors.lastname: Strupas
authors.affiliation: Center for Cancer Care, Mercy Hospital, Baltimore, MD, USA.
authors.forename: Vadim
authors.initials: V
authors.lastname: Gushchin
authors.affiliation: Center for Gastrointestinal Malignancies, MedStar Washington Hospital Center, Washington, DC, USA.
authors.forename: Paul H
authors.initials: PH
authors.lastname: Sugarbaker
keywords: CRS; Colorectal cancer; Cytoreductive surgery; HIPEC; Hyperthermic intraperitoneal chemotherapy; Ovarian cancer; Peritoneal metastases; Peritonectomy; Pseudomyxoma peritonei