title: GITIRBio: A Semantic and Distributed Service Oriented-Architecture for Bioinformatics Pipeline.
abstract: The need to process large quantities of data generated from genomic sequencing has resulted in a difficult task for life scientists who are not familiar with the use of command-line operations or developments in high performance computing and parallelization. This knowledge gap, along with unfamiliarity with necessary processes, can hinder the execution of data processing tasks. Furthermore, many of the commonly used bioinformatics tools for the scientific community are presented as isolated, unrelated entities that do not provide an integrated, guided, and assisted interaction with the scheduling facilities of computational resources or distribution, processing and mapping with runtime analysis. This paper presents the first approximation of a Web Services platform-based architecture (GITIRBio) that acts as a distributed front-end system for autonomous and assisted processing of parallel bioinformatics pipelines that has been validated using multiple sequences. Additionally, this platform allows integration with semantic repositories of genes for search annotations. GITIRBio is available at: http://c-head.ucaldas.edu.co:8080/gitirbio.
authors.affiliation: GITIR Research Group / Universidad de Caldas.
authors.forename: Luis F
authors.initials: LF
authors.lastname: Castillo
authors.affiliation: GITIR Research Group / Bioinformatics Line / Biology Department / Universidad de Caldas.
authors.forename: Germán
authors.initials: G
authors.lastname: López-Gartner
authors.affiliation: GITIR Research Group / Systems and Informatics Department / Bioinformatics Line / Universidad de Caldas / Calle 65 # 26-10 Manizales.
authors.forename: Gustavo A
authors.initials: GA
authors.lastname: Isaza
authors.affiliation: GITIR Research Group / Bioinformatics Line / Biology Department / Universidad de Caldas.
authors.forename: Mariana
authors.initials: M
authors.lastname: Sánchez
authors.affiliation: GITIR research Group / Universidad de Caldas.
authors.forename: Jeferson
authors.initials: J
authors.lastname: Arango
authors.affiliation: GITIR Research Group, Universidad de Caldas, Biolo.
authors.forename: Daniel
authors.initials: D
authors.lastname: Agudelo-Valencia
authors.affiliation: GITIR Research Group / Universidad de Caldas.
authors.forename: Sergio
authors.initials: S
authors.lastname: Castaño
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000295:instrumentation / Q000379:methods; D015894:Genome, Human / Q000502:physiology*; D006801:Humans; D020407:Internet; D058977:Molecular Sequence Annotation / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000295:instrumentation / Q000379:methods