title: MicroRNAs with Specific Roles in Diabetes and Psychiatric Diseases.
abstract: Diabetes mellitus is one of the most cited non communicable diseases and the most common metabolic disorder. Epigenetics represents the field of study of heritable changes in gene expression which are not directly related to DNA. Epigenetics is concerned, alongside histone modifications, short interfering RNAs etc., with microRNAs (miRNAs) as well. These are small noncoding RNAs, 21 to 23 nucleotides in length, which either inhibit translation or affect mRNA stability and degradation. At present, there are dozens of miRNAs which have been proven to be involved in the animal and human pathology of diabetes (type 1 or 2). This review focuses on the miRNAs which have been identified as playing a role in both psychiatric diseases and diabetes.
authors.affiliation: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Valentin
authors.initials: V
authors.lastname: Radoi
authors.affiliation: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania ; C. I. Parhon National Institute of Endocrinology, Bucharest, Romania.
authors.forename: Mara
authors.initials: M
authors.lastname: Carsote
authors.affiliation: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania ; C. I. Parhon National Institute of Endocrinology, Bucharest, Romania.
authors.forename: Rodica
authors.initials: R
authors.lastname: Petris
authors.affiliation: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania ; C. I. Parhon National Institute of Endocrinology, Bucharest, Romania.
authors.forename: Diana
authors.initials: D
authors.lastname: Paun
authors.affiliation: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania ; C. I. Parhon National Institute of Endocrinology, Bucharest, Romania.
authors.forename: Catalina
authors.initials: C
authors.lastname: Poiana
keywords: diabetes mellitus; microRNA