title: The Impacts of Early Hip Surgery in High-Risk Elderly Taking Antithrombotic Agents and Afflicted with Intertrochanteric Fracture.
abstract: OBJECTIVE
  To compare the outcome of early hip surgery in intertrochanteric fracture between high surgical risk patients receiving antiplatelet and anticoagulant drugs and those who did not.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  One hundred and four elderly patients with intertrochanteric fracture and having American Society of Anesthesiologist grade III-IV who underwent early hip surgery (within 72 hours after admission) with proximalfemoral nail anti-rotation (PFNA), were recruited and allocated into two group: antiplatelet and anticoagulant (AA-AC) group (n = 65), and no drug group (n = 39). Perioperative and postoperative outcomes were recorded and analyzed.
  
  
  RESULTS
  The mean age was 81?8 years. The overall 1-year mortality was 6.7% (7 patients: 5 AA-AC group, and 2 no drug group, p = 0.7). Intra-operative blood loss in AA-AC group and No drug group were 87 ± 70 and 91 ± 65 ml, respectively (p = 0.74). There was no significant difference in blood transfusion, postoperative complications, and 1-year ambulatory status between both groups (p > 0.05 all). However, AA-AC group showed significant longer in duration of hospital stay compared with no drug group (p = 0.02).
  
  
  CONCLUSIONS
  Early hip fracture surgery with PFNA in patients who received antiplatelet and anticoagulant medications is safe and does not significantly increase perioperative blood loss, blood transfusion, and postoperative mortality and morbidity.
authors.forename: Noratep
authors.initials: N
authors.lastname: Kulachote
authors.forename: Paphon
authors.initials: P
authors.lastname: Sa-Ngasoongsong
authors.forename: Norachart
authors.initials: N
authors.lastname: Sirisreetreerux
authors.forename: Siwadol
authors.initials: S
authors.lastname: Wongsak
authors.forename: Chanyut
authors.initials: C
authors.lastname: Suphachatwong
authors.forename: Wiwat
authors.initials: W
authors.lastname: Wajanavisit
authors.forename: Viroj
authors.initials: V
authors.lastname: Kawinwonggowit
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects; D016063:Blood Loss, Surgical; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006620:Hip Fractures / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects; D011183:Postoperative Complications / Q000601:surgery; D012189:Retrospective Studies; D012306:Risk
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors