title: Effects of soybean milk, chitosan, and anti-Streptococcus mutans IgY in malnourished rats' dental biofilm and the IgY persistency in saliva.
abstract: OBJECTIVE
  This study aims to evaluate the eff ect of soybean milk containing a combination of anti-Streptococcus mutans IgY and chitosan to the colonization of S. mutans in the saliva and to the IgY persistency in the saliva.
  
  
  METHODS
  Experimental malnourished Sprague-Dawley rats were fed with soybean milk that is enriched with anti-S. mutans IgY and chitosan. After 15 days of feeding, we evaluated the S. mutans in dental biofilm, in addition to the persistency level of anti-S. mutans IgY.
  
  
  RESULTS
  The rats that received soybean milk supplemented with anti-S. mutans IgY had the lowest number of S. mutans colonies (p < 0.05). Anti-S. mutans IgY was detected in saliva after 15 days of feeding.
  
  
  CONCLUSIONS
  Soybean milk supplemented with anti-S. mutans IgY and chitosan could signifi cantly reduce S. mutans biofilm, and the supplemented anti-S. mutans IgY persisted in these rats' saliva following the feeding period.
authors.forename: Endang W
authors.initials: EW
authors.lastname: Bachtiar
authors.forename: Retno D
authors.initials: RD
authors.lastname: Soejoedono
authors.forename: Boy M
authors.initials: BM
authors.lastname: Bachtiar
authors.forename: Alisya
authors.initials: A
authors.lastname: Henrietta
authors.forename: Nur
authors.initials: N
authors.lastname: Farhana
authors.forename: Mindya
authors.initials: M
authors.lastname: Yuniastuti
keywords: IgY; S. mutans; biofilm; chitosan; soy milk