title: Marine polysaccharide-based nanomaterials as a novel source of nanobiotechnological applications.
abstract: Research on marine polysaccharide-based nanomaterials is emerging in nanobiotechnological fields such as drug delivery, gene delivery, tissue engineering, cancer therapy, wound dressing, biosensors, and water treatment. Important properties of the marine polysaccharides include biocompatibility, biodegradability, nontoxicity, low cost, and abundance. Most of the marine polysaccharides are derived from natural sources such as fucoidan, alginates, carrageenan, agarose, porphyran, ulvan, mauran, chitin, chitosan, and chitooligosaccharide. Marine polysaccharides are very important biological macromolecules that widely exist in marine organisms. Marine polysaccharides exhibit a vast variety of structures and are still under-exploited and thus should be considered as a novel source of natural products for drug discovery. An enormous variety of polysaccharides can be extracted from marine organisms such as algae, crustaceans, and microorganisms. Marine polysaccharides have been shown to have a variety of biological and biomedical properties. Recently, research and development of marine polysaccharide-based nanomaterials have received considerable attention as one of the major resources for nanotechnological applications. This review highlights the recent research on marine polysaccharide-based nanomaterials for biotechnological and biomedical applications.
authors.affiliation: Marine-Integrated Bionics Research Center, Pukyong National University, Busan 608-737, Republic of Korea.
authors.forename: Panchanathan
authors.initials: P
authors.lastname: Manivasagan
authors.affiliation: Marine-Integrated Bionics Research Center, Pukyong National University, Busan 608-737, Republic of Korea; Department of Biomedical Engineering and Center for Marine-Integrated Biotechnology (BK21 Plus), Pukyong National University, Busan 608-737, Republic of Korea. Electronic address: jungoh@pknu.ac.kr.
authors.forename: Junghwan
authors.initials: J
authors.lastname: Oh
mesh_terms: D059001:Aquatic Organisms / Q000737:chemistry*; D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D001709:Biotechnology; D004337:Drug Carriers / Q000737:chemistry; D016503:Drug Delivery Systems; D018973:Intellectual Property; D049329:Nanostructures / Q000737:chemistry* / Q000627:therapeutic use; D036103:Nanotechnology; D011134:Polysaccharides / Q000737:chemistry*; D023822:Tissue Engineering
chemical_list: D001672:Biocompatible Materials; D004337:Drug Carriers; D011134:Polysaccharides
keywords: Biomedical applications; Drug delivery; Marine polysaccharides; Nanomaterials; Nanoparticles