title: Neuromyelitis Optica (NMO) with Abdominal Tuberculosis (TB).
abstract: Neuromyelitis Optica (NMO), previously regarded as a form of multiple sclerosis, is defined by Gault and Devic, as a retrobulbar neuritis or papillitis accompanied by acute myelitis and occasionally other neurological symptom or signs not restricted to the spinal cord or optic nerves. With the diagnosis of specific antibodies, probable role of humoral immunity supports its pathogenesis. Only a few cases of NMO have been reported in association with pulmonary tuberculosis (TB). Here we report a case of young girl with acute onset paraplegia diagnosed to have NMO, who later on during hospital stay developed ascites which cultured positive for Mycobacterium tuberculosis. This association of abdominal TB with NMO is under-reported in literature.
authors.affiliation: Department of Medicine, Dow Medical College, Karachi.
authors.forename: Shaheen A
authors.initials: SA
authors.lastname: Bhatty
authors.affiliation: Department of Medicine, Dow Medical College, Karachi.
authors.forename: Hari
authors.initials: H
authors.lastname: Lal
authors.affiliation: Department of Medicine, Dow Medical College, Karachi.
authors.forename: Abu
authors.initials: A
authors.lastname: Talib
authors.affiliation: Department of Medicine, Dow Medical College, Karachi.
authors.forename: Khalid
authors.initials: K
authors.lastname: Mahmood
authors.affiliation: Department of Medicine, Dow Medical College, Karachi.
authors.forename: Iftekhar
authors.initials: I
authors.lastname: Naqvi
authors.affiliation: Department of Medicine, Dow Medical College, Karachi.
authors.forename: Syeda Shaheera
authors.initials: SS
authors.lastname: Zaidi
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D009471:Neuromyelitis Optica / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D010264:Paraplegia / Q000209:etiology; D013116:Spinal Cord / Q000473:pathology; D016896:Treatment Outcome; D014376:Tuberculosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents; D008775:Methylprednisolone