title: Altered Basal Ganglia Network Integration in Schizophrenia.
abstract: The basal ganglia involve in a range of functions that are disturbed in schizophrenia patients. This study decomposed the resting-state data of 28 schizophrenia patients and 31 healthy controls with spatial independent component analysis and identified increased functional integration in the bilateral caudate nucleus in schizophrenia patients. Further, the caudate nucleus in patients showed altered functional connection with the prefrontal area and cerebellum. These results identified the importance of basal ganglia in schizophrenia patients.
  
  
  BACKGROUND
  Chinese Clinical Trial Registry. Registration number ChiCTR-RCS-14004878.
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China ; The Fourth People's Hospital of Chengdu , Chengdu , China.
authors.forename: Mingjun
authors.initials: M
authors.lastname: Duan
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China.
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China.
authors.forename: Hui
authors.initials: H
authors.lastname: He
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China.
authors.forename: Yuchao
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China.
authors.forename: Sisi
authors.initials: S
authors.lastname: Jiang
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China.
authors.forename: Qiankun
authors.initials: Q
authors.lastname: Xie
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China.
authors.forename: Yongxiu
authors.initials: Y
authors.lastname: Lai
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Luo
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, Center for Information in Medicine, High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province, School of Life Science and Technology, University of Electronic Science and Technology of China , Chengdu , China.
authors.forename: Dezhong
authors.initials: D
authors.lastname: Yao
keywords: basal ganglia network; functional connectivity; independent component analysis; resting-state fMRI; schizophrenia