title: Endocrine tumours in the guinea pig.
abstract: Functional endocrine tumours have long been thought to be rare in guinea pigs, although conditions such as hyperthyroidism and hyperadrenocorticism have been documented with increasing frequency so the prevalence of hormonal disorders may have been underestimated. Both the clinical signs and diagnosis of hyperthyroidism in guinea pigs appear to be very similar to those described in feline hyperthyroidism, and methimazole has been proven to be a practical therapy option. Hyperadrenocorticism has been confirmed in several guinea pigs with an adrenocorticotropic hormone stimulation test using saliva as a non-invasive sample matrix; trilostane has been successfully used to treat a guinea pig with hyperadrenocorticism. Insulinomas have only rarely been documented in guinea pigs and one animal was effectively treated with diazoxide.
authors.affiliation: Clinical Department of Small Animals and Horses, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210 Vienna, Austria. Electronic address: Frank.Kuenzel@vetmeduni.ac.at.
authors.forename: Frank
authors.initials: F
authors.lastname: Künzel
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
authors.forename: Jörg
authors.initials: J
authors.lastname: Mayer
mesh_terms: D000308:Adrenocortical Hyperfunction / Q000662:veterinary; D000818:Animals; D004701:Endocrine Gland Neoplasms / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D006168:Guinea Pigs; D006980:Hyperthyroidism / Q000662:veterinary; D007340:Insulinoma / Q000662:veterinary
keywords: Guinea pig; Hyperadrenocorticism; Hyperthyroidism; Insulinoma; Thyroid gland tumours