title: Burkholderia pseudomallei Genotype Distribution in the Northern Territory, Australia.
abstract: Melioidosis is a tropical disease of high mortality caused by the environmental bacterium, Burkholderia pseudomallei. We have collected clinical isolates from the highly endemic Northern Territory of Australia routinely since 1989, and animal and environmental B. pseudomallei isolates since 1991. Here we provide a complete record of all B. pseudomallei multilocus sequence types (STs) found in the Northern Territory to date, and distribution maps of the eight most common environmental STs. We observed surprisingly restricted geographic distributions of STs, which is contrary to previous reports suggesting widespread environmental dissemination of this bacterium. Our data suggest that B. pseudomallei from soil and water does not frequently disperse long distances following severe weather events or by migration of infected animals.
authors.affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia; Imperial College, London, United Kingdom; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
authors.forename: Stephanie N J
authors.initials: SN
authors.lastname: Chapple
authors.affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia; Imperial College, London, United Kingdom; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
authors.forename: Erin P
authors.initials: EP
authors.lastname: Price
authors.affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia; Imperial College, London, United Kingdom; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
authors.forename: Derek S
authors.initials: DS
authors.lastname: Sarovich
authors.affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia; Imperial College, London, United Kingdom; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
authors.forename: Evan
authors.initials: E
authors.lastname: McRobb
authors.affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia; Imperial College, London, United Kingdom; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
authors.forename: Mark
authors.initials: M
authors.lastname: Mayo
authors.affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia; Imperial College, London, United Kingdom; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
authors.forename: Mirjam
authors.initials: M
authors.lastname: Kaestli
authors.affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia; Imperial College, London, United Kingdom; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
authors.forename: Brian G
authors.initials: BG
authors.lastname: Spratt
authors.affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia; Imperial College, London, United Kingdom; Department of Infectious Diseases and Northern Territory Medical Program, Royal Darwin Hospital, Darwin, Northern Territory, Australia bart.currie@menzies.edu.au.
authors.forename: Bart J
authors.initials: BJ
authors.lastname: Currie
mesh_terms: D000818:Animals; D016957:Burkholderia pseudomallei / Q000235:genetics*; D005838:Genotype; D006801:Humans; D008554:Melioidosis / Q000453:epidemiology / Q000382:microbiology*; D015876:Northern Territory / Q000453:epidemiology; D010802:Phylogeny; D012988:Soil Microbiology; D014871:Water Microbiology