title: Role of proteomics in physiologic and pathologic conditions of dentistry: Overview.
abstract: Proteomics is the study of structure and function of proteins in a large scale. For any living organism, preteins are considered to be the vital part because of its role in metabolic pathways of cells. These proteins not only play a role in physiological condition of the cell but also in altered manner during pathologic conditions. These altered proteins in diseased conditions are called as biomarkers. Several such biomarkers were identified in oral diseaes. This review is a brief note on proteins involved in odontogenesis and list of altered proteins proteins identified in various dental and oral diseases. The knowledge about the role of proteomics in dentistry and the importance of proteomic studies in early diagnosis and prognostic part of oral diseases helps in appliction of precised and sucessful treatment.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Vivekanandha Dental College for Women, Tiruchengode, Tamilnadu, India.
authors.forename: Thukanayakanpalayam Ragunathan
authors.initials: TR
authors.lastname: Yoithapprabhunath
authors.affiliation: Department of Oral and Maxillofacial Pathology, Rajah Muthiah Dental College and Hospital, Chidambaram, Tamilnadu, India.
authors.forename: Ramadas Madhavan
authors.initials: RM
authors.lastname: Nirmal
authors.affiliation: Department of Oral and Maxillofacial Pathology, Indhra Gandhi Institute of Dental Sciences, Pudhucherry, India.
authors.forename: Arumugam
authors.initials: A
authors.lastname: Santhadevy
authors.affiliation: Department of Oral Medicine and Radiology, Educare Institute of Dental Sciences, Kerela, India.
authors.forename: Abraham
authors.initials: A
authors.lastname: Anusushanth
authors.affiliation: Department of Oral Medicine and Radiology, Madha Dental College and Hospital, Tamilnadu, India.
authors.forename: Duraisamy
authors.initials: D
authors.lastname: Charanya
authors.affiliation: Department of Periodontia, Educare Institute of Dental Sciences, Malappuram, Kerela, India.
authors.lastname: Rojiluke
authors.affiliation: Department of Oral Medicine and Radiology, K.S.R. Institute of Dental Science and Research, Tamil Nadu, India.
authors.forename: K K
authors.initials: KK
authors.lastname: Sri Chinthu
authors.affiliation: Department of Oral and Maxillofacial Pathology, Vivekanandha Dental College for Women, Tiruchengode, Tamilnadu, India.
authors.forename: Andamuthu
authors.initials: A
authors.lastname: Yamunadevi
keywords: Biomarkers; cancer proteomics; proteins