title: Photoresponsive molecular switch for regulating transmembrane proton-transfer kinetics.
abstract: To control proton delivery across biological membranes, we synthesized a photoresponsive molecular switch and incorporated it in a lipid layer. This proton gate was reversibly activated with 390 nm light (Z-isomer) and then deactivated by 360 nm irradiation (E-isomer). In a lipid layer this stimuli responsive proton gate allowed the regulation of proton flux with irradiation to a lipid-buried O2 reduction electrocatalyst. Thus, the catalyst was turned on and off with the E-to-Z interconversion. This light-induced membrane proton delivery system may be useful in developing any functional device that performs proton-coupled electron-transfer reactions.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Edmund C M
authors.initials: EC
authors.lastname: Tse
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Barile
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.|International Institute for Carbon Neutral Energy Research (WPI-I2CNER), Kyushu University , Fukuoka 812-8581, Japan.
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Gewirth
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Steven C
authors.initials: SC
authors.lastname: Zimmerman
mesh_terms: D004579:Electron Transport; D007700:Kinetics; D008027:Light; D008051:Lipid Bilayers / Q000737:chemistry*; D015394:Molecular Structure; D055668:Photochemical Processes; D011522:Protons; D013237:Stereoisomerism; D013267:Stilbenes / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D008051:Lipid Bilayers; D011522:Protons; D013267:Stilbenes