title: Riboswitch Scanner: an efficient pHMM-based web-server to detect riboswitches in genomic sequences.
abstract: Riboswitches are non-coding RNA located in the 5' untranslated regions where they bind a target metabolite used to specify the riboswitch class and control the expression of associated genes. Accurate identification of riboswitches is the first step towards understanding their regulatory and functional roles in the cell. In this article, we describe a new web application named Riboswitch Scanner which provides an automated pipeline for pHMM-based detection of riboswitches in partial as well as complete genomic sequences rapidly, with high sensitivity and specificity.
  
  
  
  Riboswitch Scanner can be freely accessed on the web at http://service.iiserkol.ac.in/∼riboscan/
  
  
  
  mukherjee.sumit89@gmail.com
  
  
  
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Department of Physical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur-741246, West Bengal, India.
authors.forename: Sumit
authors.initials: S
authors.lastname: Mukherjee
authors.affiliation: Department of Physical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur-741246, West Bengal, India.
authors.forename: Supratim
authors.initials: S
authors.lastname: Sengupta
mesh_terms: D023281:Genomics; D058928:Riboswitch
chemical_list: D058928:Riboswitch