title: Symptoms of Central Anticholinergic Syndrome After Glycopyrrolate Administration in a 5-Year-Old Child.
abstract: Anesthesia-related central anticholinergic syndrome (CAS) is most commonly associated with administration of atropine or scopolamine, whereas glycopyrrolate is an extremely rare cause of CAS. Here, we report a case of CAS in a 5-year-old boy admitted to the intensive care unit. Immediately after the administration of glycopyrrolate, he became agitated and developed apnea, hypertension, tachycardia, and anuria. Although the present case describes a rare cause of CAS, it is an important reminder of an iatrogenic condition that is presumably underdiagnosed in the operating theater as well as the intensive care unit.
authors.affiliation: From the *Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark; †Department of Anaesthesiology, Køge Sygehus, Køge, Denmark; and ‡Department of Intensive Care, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
authors.forename: Linea Natalie
authors.initials: LN
authors.lastname: Toksvang
authors.forename: Ronni R
authors.initials: RR
authors.lastname: Plovsing
mesh_terms: D064807:Anticholinergic Syndrome / Q000209:etiology* / Q000473:pathology; D002675:Child, Preschool; D017809:Fatal Outcome; D006024:Glycopyrrolate / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male
chemical_list: D006024:Glycopyrrolate