title: [The use of piribedil in early and late stages of Parkinson's disease].
abstract: In this article, we present clinical cases at an early stage of Parkinson's disease with mild affective and cognitive disorders, and at a later stage with motor fluctuations and levodopa-induced dyskinesia. The efficacy of dopamine receptor agonists in treatment of Parkinson's disease in the early and late stages is illustrated by the example of piribedil.
authors.affiliation: Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia; Center of Extrapyramidal Disorders, Moscow.
authors.forename: N V
authors.initials: NV
authors.lastname: Fedorova
authors.affiliation: Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia; Center of Extrapyramidal Disorders, Moscow.
authors.forename: T K
authors.initials: TK
authors.lastname: Kulua
authors.affiliation: Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia; Center of Extrapyramidal Disorders, Moscow.
authors.forename: Е N
authors.initials: ЕN
authors.lastname: Gubanova
mesh_terms: D000978:Antiparkinson Agents / Q000627:therapeutic use*; D018491:Dopamine Agonists / Q000627:therapeutic use*; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy* / Q000523:psychology; D010891:Piribedil / Q000627:therapeutic use*
chemical_list: D000978:Antiparkinson Agents; D018491:Dopamine Agonists; D007980:Levodopa; D010891:Piribedil