title: Bone health and its correlates in Korean prostate cancer patients receiving androgen deprivation therapy.
abstract: OBJECTIVE
  This study aimed to examine bone health status, identify factors associated with bone mineral density (BMD), and determine potential risk factors for osteoporosis in Korean prostate cancer patients receiving androgen deprivation therapy (ADT).
  
  
  METHODS
  Using a cross-sectional descriptive design, we recruited 139 men with prostate cancer receiving ADT at two university-based hospitals in South Korea. Participants completed a self-reported questionnaire and underwent dual energy X-ray absorptiometry testing. BMD (gm/cm(2)), bone health status (normal BMD, osteopenia, and osteoporosis), and lifestyle variables (physical activity, smoking, and alcohol consumption) were measured.
  
  
  RESULTS
  The prevalence in our sample was 49.6% for osteopenia and 17.3% for osteoporosis. In multivariate linear regression analyses, BMD was positively associated with body mass index, number of comorbidities, and level of physical activity and negatively associated with being unemployed or retired, having a lower monthly income, and being treated with gonadotropin-releasing hormone therapy alone. In logistic regression analyses, potential risk factors for osteoporosis were low monthly income (OR = 4.33, p = 0.011), receipt of radiation therapy (OR = 4.69, p = 0.018), and lack of regular physical activity (OR = 2.63, p = 0.035).
  
  
  CONCLUSIONS
  Our results suggest that a proportion of prostate cancer survivors who are receiving ADT warrant monitoring to prevent osteoporosis, particularly men of lower economic status and those having lower levels of physical activity. Nurses can play an important role in screening these high risk groups.
authors.affiliation: Department of Nursing, Inha University, Incheon, South Korea. Electronic address: soohyun@inha.ac.kr.
authors.forename: Soo Hyun
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Urology, Inha University Hospital and College of Medicine, Inha University, Incheon, South Korea.
authors.forename: Do Hwan
authors.initials: do H
authors.lastname: Seong
authors.affiliation: Department of Urology, Inha University Hospital and College of Medicine, Inha University, Incheon, South Korea.
authors.forename: Sang Min
authors.initials: SM
authors.lastname: Yoon
authors.affiliation: Department of Urology, Clinical Trials Center for Medical Devices, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Young Deuk
authors.initials: YD
authors.lastname: Choi
authors.affiliation: Graduate School, Catholic University, Seoul, South Korea.
authors.forename: Youngkyu
authors.initials: Y
authors.lastname: Song
authors.affiliation: Department of Urology, Inha University Hospital, Incheon; College of Nursing, Ajou University, Suwon, South Korea.
authors.forename: Hosook
authors.initials: H
authors.lastname: Song
authors.affiliation: Department of Nursing, Inha University, Incheon, South Korea.
authors.forename: Eunju
authors.initials: E
authors.lastname: Choi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000726:Androgen Antagonists / Q000627:therapeutic use*; D015519:Bone Density; D003430:Cross-Sectional Studies; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology*; D015995:Prevalence; D011471:Prostatic Neoplasms / Q000150:complications / Q000188:drug therapy*; D056910:Republic of Korea; D012307:Risk Factors; D012959:Socioeconomic Factors
chemical_list: D000726:Androgen Antagonists
keywords: Bone density; Exercise; Osteoporosis; Prostate cancer; Smoking