title: The Tussle Between Mycobacteria and Host: To Eat or Not To Eat.
abstract: Autophagy is a catabolic process of cellular homeostasis evolutionarily conserved in eukaryotes. To block infection of intracellular bacterial pathogens, metazoans deploy autophagy for pathogen clearance through phago-lysosome formation and specific bactericidal peptides. Although an array of research have publicized the host regulatory factors, the function of bacterial effectors are yet to be understood in detail. In this article, we focus on the autophagic response to one of the most successful intracellular bacteria Mycobacterium tuberculosis.
authors.affiliation: Cluster Innovation Centre, University of Delhi, Delhi, 110007 India.
authors.forename: Asani
authors.initials: A
authors.lastname: Bhaduri
authors.affiliation: Miranda House, University of Delhi, Delhi, 110007 India.
authors.forename: Richa
authors.initials: R
authors.lastname: Misra
authors.affiliation: Daulat Ram College, University of Delhi, Delhi, 110007 India.
authors.forename: Neeru
authors.initials: N
authors.lastname: Dhamija
keywords: Autophagy; Host–pathogen interaction; Mycobacteria; Mycobacterium tuberculosis; Tuberculosis; Virulence factors