title: Implication of Sarcopenia and Sarcopenic Obesity on Lung Function in Healthy Elderly: Using Korean National Health and Nutrition Examination Survey.
abstract: Previous studies have demonstrated a positive association between obesity and decreased lung function. However, the effect of muscle and fat has not been fully assessed, especially in a healthy elderly population. In this study, we evaluated the impact of low muscle mass (LMM) and LMM with obesity on pulmonary impairment in healthy elderly subjects. Our study used data from the Korea National Health and Nutrition Examination Survey from 2008 to 2011. Men and women aged 65 yr or older were included. Muscle mass was measured by dual-energy X-ray absorptiometry. LMM was defined as two standard deviations below the sex-specific mean for young healthy adults. Obesity was defined as body mass index ≥ 25 kg/m(2). The prevalence of LMM in individuals aged over 65 was 11.9%. LMM and pulmonary function (forced vital capacity and forced expiratory volume in 1 second) were independently associated after adjusting for age, sex, body mass index, smoking status, alcohol consumption, and frequency of exercise. LMM with obesity was also related to a decrease in pulmonary function. This study revealed that LMM is an independent risk factor of decreased pulmonary function in healthy Korean men and women over 65 yr of age.
authors.affiliation: Department of Family Medicine, Jeju National University Hospital, Jeju, Korea. ; Graduate School of Jeju National University, Jeju, Korea.
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Moon
authors.affiliation: Department of Family Medicine, Jeju National University Hospital, Jeju, Korea. ; Department of Family Medicine, School of Medicine, Jeju National University, Jeju, Korea.
authors.forename: Mi Hee
authors.initials: MH
authors.lastname: Kong
authors.affiliation: Department of Family Medicine, Jeju National University Hospital, Jeju, Korea. ; Department of Family Medicine, School of Medicine, Jeju National University, Jeju, Korea.
authors.forename: Hyeon Ju
authors.initials: HJ
authors.lastname: Kim
mesh_terms: D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015984:Causality; D015897:Comorbidity; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000453:epidemiology* / Q000473:pathology*; D008297:Male; D009749:Nutrition Surveys; D009765:Obesity / Q000453:epidemiology* / Q000473:pathology; D009929:Organ Size; D015995:Prevalence; D012016:Reference Values; D015203:Reproducibility of Results; D056910:Republic of Korea / Q000453:epidemiology; D012129:Respiratory Function Tests; D012132:Respiratory Muscles / Q000473:pathology*; D012307:Risk Factors; D055948:Sarcopenia / Q000453:epidemiology* / Q000473:pathology*; D012680:Sensitivity and Specificity; D017678:Sex Distribution
keywords: Aged; Body Mass Index; Low Muscle Mass; Obesity; Respiratory Function Tests