title: Risperidone, quetiapine and chlorpromazine may have induced priapism in an adolescent.
abstract: Priapism is the prolonged, painful erection of penile tissue not accompanied by sexual arousal. Priapism has been established as a rare adverse drug reaction to drugs such as antipsychotics, psychostimulants, antidepressants, and mood stabilizers. Immediate intervention is needed to prevent destructive and irreversible complications, such as erectile dysfunction, disfigurement, inability of the penis to stay erect, and related social/emotional problems. Antipsychotic-induced priapism may result from the alpha receptor occupancy property of those drugs. We report the case of a 13-year-old suffering from attention deficit-hyperactivity disorder plus conduct disorder with priapism related to antipsychotics. Episodes occurred with risperidone plus methylphenidate, quetiapine plus methylphenidate, and chlorpromazine alone.
authors.affiliation: Child and Adolescent Psychiatry Department, School of Medicine, Ege University, Izmir, Turkey.
authors.forename: Muharrem Burak
authors.initials: MB
authors.lastname: Baytunca
authors.affiliation: Child and Adolescent Psychiatry Department, School of Medicine, Ege University, Izmir, Turkey.
authors.forename: Sezen
authors.initials: S
authors.lastname: Kose
authors.affiliation: Child and Adolescent Psychiatry Department, School of Medicine, Ege University, Izmir, Turkey.
authors.forename: Burcu
authors.initials: B
authors.lastname: Ozbaran
authors.affiliation: Child and Adolescent Psychiatry Department, School of Medicine, Ege University, Izmir, Turkey.
authors.forename: Serpil
authors.initials: S
authors.lastname: Erermis
mesh_terms: D000293:Adolescent; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy*; D002746:Chlorpromazine / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D010413:Penis / Q000000981:diagnostic imaging* / Q000187:drug effects; D011317:Priapism / Q000139:chemically induced* / Q000175:diagnosis; D000069348:Quetiapine Fumarate / Q000009:adverse effects* / Q000627:therapeutic use; D018967:Risperidone / Q000009:adverse effects* / Q000627:therapeutic use; D018608:Ultrasonography, Doppler
chemical_list: D014150:Antipsychotic Agents; D000069348:Quetiapine Fumarate; D018967:Risperidone; D002746:Chlorpromazine
keywords: children; chlorpromazine; priapism; quetiapine; risperidone