title: Translational progress on tumor biomarkers.
abstract: There is an urgent need to apply basic research achievements to the clinic. In particular, mechanistic studies should be developed by bench researchers, depending upon clinical demands, in order to improve the survival and quality of life of cancer patients. To date, translational medicine has been addressed in cancer biology, particularly in the identification and characterization of novel tumor biomarkers. This review focuses on the recent achievements and clinical application prospects in tumor biomarkers based on translational medicine.
authors.affiliation: Key Laboratory of Longevity and Aging-Related Diseases, Ministry of Education Nanning, China ; Center for Translational Medicine, Guangxi Medical University Nanning, China.
authors.forename: Hongwei
authors.initials: H
authors.lastname: Guo
authors.affiliation: Key Laboratory of Longevity and Aging-Related Diseases, Ministry of Education Nanning, China ; Center for Translational Medicine, Guangxi Medical University Nanning, China.
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Longevity and Aging-Related Diseases, Ministry of Education Nanning, China ; Center for Translational Medicine, Guangxi Medical University Nanning, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Key Laboratory of Longevity and Aging-Related Diseases, Ministry of Education Nanning, China ; Center for Translational Medicine, Guangxi Medical University Nanning, China.
authors.forename: Liye
authors.initials: L
authors.lastname: Xie
authors.affiliation: Key Laboratory of Longevity and Aging-Related Diseases, Ministry of Education Nanning, China ; Center for Translational Medicine, Guangxi Medical University Nanning, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Department of Urology and Pathology, School of Medicine, University of Michigan Ann Arbor, Michigan, USA.
authors.forename: Evan T
authors.initials: ET
authors.lastname: Keller
authors.affiliation: Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital Tianjin, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Lung Cancer Center, Huaxi Hospital, Sichuan University Chengdu, China.
authors.forename: Qinghua
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Longevity and Aging-Related Diseases, Ministry of Education Nanning, China ; Center for Translational Medicine, Guangxi Medical University Nanning, China ; Department of Urology and Pathology, School of Medicine, University of Michigan Ann Arbor, Michigan, USA.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
keywords: Targeted therapy; translational medicine; tumor biomarkers