title: [Hyperechoic Breast Lesions on Ultrasound:Easily Misdiagnosed Conditions].
abstract: OBJECTIVE
  To evaluate the incidences of hyperechoic breast lesions and hyperechoic breast cancers in lesions categorized as Breast Imaging Reporting and Data System (BI-RADS) 4 and 5 on ultrasound and investigate their sonographic features and the underlying histological causes.
  
  
  METHODS
  The pathologic records for 848 sonographically guided core needle biopsies or surgical resection were retrospectively reviewed from June 2012 to March 2014. Hyperechoic lesions were identified and their sonographic features were evaluated. The incidence of hyperechoic breast lesions and the frequency of hyperechoic cancers among all hyperechoic breast lesions were calculated.
  
  
  RESULTS
  Of all 848 lesions, 0.9% (8/848) were hyperechoic. Twenty-five percent (2/8) of the hyperechoic lesions were malignant and the remaining six were benign. Among the 280 malignant lesions, 0.7%(2/280) were hyperechoic. The pathological basis of breast lesions presenting as hyperechoic nodules included inflammatory edema, galactoceles, and grit calcifications. Little difference of sonographic feature was found between benign and malignant hyperechoic lesions in this study.
  
  
  CONCLUSIONS
  Hyperechoic breast lesions are rare conditions but can be associated with a high ratio of breast cancer. History-taking and imaging techniques may help to avoid misdiagnosis.
authors.affiliation: Department of Diagnostic Ultrasound,Peking University Third Hospital,100191 Beijing,China2Breast Center,Peking University Cancer Hospital,100142 Beijing,China.
authors.forename: Xin-yi
authors.initials: XY
authors.lastname: Wang
authors.affiliation: Department of Diagnostic Ultrasound,Peking University Third Hospital,100191 Beijing,China2Breast Center,Peking University Cancer Hospital,100142 Beijing,China.
authors.forename: Li-gang
authors.initials: LG
authors.lastname: Cui
authors.forename: Ling
authors.initials: L
authors.lastname: Huo
mesh_terms: D047688:Breast Cyst; D001943:Breast Neoplasms; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D015994:Incidence; D012189:Retrospective Studies; D016217:Ultrasonography, Mammary