title: Concomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma.
abstract: A 10-year-old girl with a family history of Hodgkin's lymphoma presented with a 2 month history of cervical lymphadenopathy and weight loss. Biopsy indicated concomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma. Such an association is rare, especially so in children, but is not an isolated phenomenon, thereby prompting the question of whether Langerhans cell histiocytosis is a reactive or a neoplastic process.
authors.affiliation: Faculty of Medicine, University of Liege.
authors.forename: Claire
authors.initials: C
authors.lastname: Geurten
authors.affiliation: Department of Anatomopathology, Clinique CHR de la Citadelle, Liège, Belgium.
authors.forename: Albert
authors.initials: A
authors.lastname: Thiry
authors.affiliation: Department of Radiology, Clinique CHR de la Citadelle, Liège, Belgium.
authors.forename: Paul
authors.initials: P
authors.lastname: Jamblin
authors.affiliation: Division of Pediatric surgery, Department of General Surgery, Clinique CHR de la Citadelle, Liège, Belgium.
authors.forename: Martine
authors.initials: M
authors.lastname: Demarche
authors.affiliation: Division of Pediatric Hematology-Oncology, Department of Pediatrics, La Citadelle Regional Hospital, Liège, Belgium.
authors.forename: Claire
authors.initials: C
authors.lastname: Hoyoux
mesh_terms: D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000209:etiology*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
keywords: Hodgkin's lymphoma; Langerhans cell histiocytosis; neoplasm; pediatric; synchronous