title: Transcriptional control of cell fate in the stomatal lineage.
abstract: The Arabidopsis stomatal lineage is a microcosm of development; it undergoes selection of precursor cells, asymmetric and stem cell-like divisions, cell commitment and finally, acquisition of terminal cell fates. Recent transcriptomic approaches revealed major shifts in gene expression accompanying each fate transition, and mechanistic analysis of key bHLH transcription factors, along with mathematical modeling, has begun to unravel how these major shifts are coordinated. In addition, stomatal initiation is proving to be a tractable model for defining the genetic and epigenetic basis of stable cell identities and for understanding the integration of environmental responses into developmental programs.
authors.affiliation: Department of Biology, Stanford University, Stanford, CA 94305-5020, USA.
authors.forename: Abigail R
authors.initials: AR
authors.lastname: Simmons
authors.affiliation: Department of Biology, Stanford University, Stanford, CA 94305-5020, USA; HHMI, 371 Serra Mall, Stanford University, Stanford, CA 94305-5020, USA. Electronic address: dbergmann@stanford.edu.
authors.forename: Dominique C
authors.initials: DC
authors.lastname: Bergmann
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development*; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics* / Q000378:metabolism; D002454:Cell Differentiation; D018506:Gene Expression Regulation, Plant; D008954:Models, Biological; D054046:Plant Stomata / Q000235:genetics / Q000254:growth & development
chemical_list: D029681:Arabidopsis Proteins; D051792:Basic Helix-Loop-Helix Proteins