title: The relationship between glycated hemoglobin and blood glucose levels of 75 and 100 gram oral glucose tolerance test during gestational diabetes diagnosis.
abstract: OBJECTIVE
  The diagnosis of gestational diabetes mellitus (GDM) is an important issue in terms of prevention of maternal and fetal complications. In our study we aimed to evaluate the relation of HbA1c and blood glucose levels of 75 and 50-100 gram oral glucose tolerance test (OGTT) in pregnant patients who were screened for GDM.
  
  
  METHODS
  The parameters of 913 pregnant women screened for GDM are evaluated retrospectively. The two steps screening with 50-100 gram OGTT were used in 576 patients. The remaining 337 patients were screened with 75 gram OGTT.
  
  
  RESULTS
  The HbA1c levels of patients having high blood glucose (≥153 mg/dl) levels at 2(nd) hour in 75 gram OGTT were significantly higher than patients having normal blood glucose levels at 2(nd) hour of 75 gram OGTT (P=0.038). Correlation analyses showed no significant relation between any blood glucose level of 100 gram OGTT and HbA1c level. Whereas in 75 gram OGTT 1(st) and 2(nd) hour blood glucose levels were found to have a significant relation with A1c levels (P=0.001, P=0.001 respectively).
  
  
  CONCLUSIONS
  HbA1c may be used as an important tool in the diagnosis of GDM. But due to the variation of HbA1c in pregnant women and there is not an absolute cut-off level for A1c, it may be more reliable to evaluate HbA1c level together with the blood glucose levels in OGTT.
authors.affiliation: Department of Endocrinology and Metabolism, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Meral
authors.initials: M
authors.lastname: Mert
authors.affiliation: Department of Family Medicine, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Serhat
authors.initials: S
authors.lastname: Purcu
authors.affiliation: Department of Endocrinology and Metabolism, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Soyluk
authors.affiliation: Department of Internal Medicine, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Yildiz
authors.initials: Y
authors.lastname: Okuturlar
authors.affiliation: Department of Endocrinology and Metabolism, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Karakaya
authors.affiliation: Department of Endocrinology and Metabolism, Istanbul Medeniyet University, Goztepe Education and Research Hospital Istanbul, Turkey.
authors.forename: Gonca
authors.initials: G
authors.lastname: Tamer
authors.affiliation: Department of Endocrinology and Metabolism, Okmeydani Education and Research Hospital Istanbul, Turkey.
authors.forename: Mine
authors.initials: M
authors.lastname: Adas
authors.affiliation: Department of Obstetrics and Gynecology, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Ekin
authors.affiliation: Department of Pediatrics, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Sami
authors.initials: S
authors.lastname: Hatipoglu
authors.affiliation: Department of Internal Medicine, Kecioren Education and Research Hospital Ankara, Turkey.
authors.forename: Oznur Sari
authors.initials: OS
authors.lastname: Ure
authors.affiliation: Department of Internal Medicine, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Harmankaya
authors.affiliation: Department of Internal Medicine, Bakirkoy Dr. Sadi Konuk Education and Research Hospital Istanbul, Turkey.
authors.forename: Abdulbaki
authors.initials: A
authors.lastname: Kumbasar
keywords: A1c; Gestational diabetes mellitus; postload glucose