title: High rate of vaccine failure after administration of acellular pertussis vaccine pre- and post-liver transplantation in children at a children's hospital in Japan.
abstract: We assessed the serological response to pertussis vaccines administered pre- and post-liver transplantation in 58 pediatric patients at a children's hospital in Japan. A high rate of pertussis vaccine failure was observed, 44.8% against the pertussis toxin and 69.0% against filamentous hemagglutinin, with no difference in the seropositivity rate with respect to the timing of the vaccination during the peritransplant period.
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Medical Specialties, National Center for Child Health and Development, Tokyo, Japan.|Department of Infectious Diseases, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ito
authors.affiliation: Division of Transplant Surgery, Department of Surgical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kasahara
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Medical Specialties, National Center for Child Health and Development, Tokyo, Japan.|Department of Pediatrics, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Saitoh
authors.affiliation: Division of Infectious Diseases, Tokyo Metropolitan Tama General Medical Center, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Honda
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Medical Specialties, National Center for Child Health and Development, Tokyo, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Miyairi
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood*; D001886:Bordetella pertussis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D007564:Japan; D016031:Liver Transplantation; D008297:Male; D010567:Pertussis Vaccine / Q000276:immunology*; D012189:Retrospective Studies; D014611:Vaccination; D014917:Whooping Cough / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D000907:Antibodies, Bacterial; D010567:Pertussis Vaccine
keywords: acellular pertussis vaccine; liver transplantation; pediatrics