title: Association of Metabolic Syndrome with the Adiponectin to Homeostasis Model Assessment of Insulin Resistance Ratio.
abstract: This study aimed at determining whether the adiponectin to HOMA-IR (A/H) ratio is associated with MetS and MetS components and comparing the diagnostic efficacy of adiponectin, HOMA-IR, and the A/H ratio in healthy, middle-aged participants. MetS was assessed in 1628 Kazakh participants (men, 768; women, 860). The associations between adiponectin, HOMA-IR, and the A/H ratio with the components of MetS and MetS were examined using logistic regression analysis and receiver operating characteristic (ROC) curves. Our results show that A/H ratio may be a better diagnostic marker for MetS than either HOMA-IR or adiponectin alone, and it may serve as an important biomarker to determine an increased risk for MetS in healthy middle-aged population.
authors.affiliation: Department of Nutrition and Food Hygiene, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China ; Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Yu-Song
authors.initials: YS
authors.lastname: Ding
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China ; Department of Pathology and Key Laboratory of Xinjiang Endemic and Ethnic Diseases (Ministry of Education), Shihezi University School of Medicine, Shihezi, Xinjiang 832002, China.
authors.forename: Shu-Xia
authors.initials: SX
authors.lastname: Guo
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Ru-Lin
authors.initials: RL
authors.lastname: Ma
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Shu-Gang
authors.initials: SG
authors.lastname: Li
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Heng
authors.initials: H
authors.lastname: Guo
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Jing-Yu
authors.initials: JY
authors.lastname: Zhang
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Mei
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Jia-Ming
authors.initials: JM
authors.lastname: Liu
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Jia
authors.initials: J
authors.lastname: He
authors.affiliation: Department of Public Health, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Yi-Zhong
authors.initials: YZ
authors.lastname: Yan
authors.affiliation: Department of Pathology and Key Laboratory of Xinjiang Endemic and Ethnic Diseases (Ministry of Education), Shihezi University School of Medicine, Shihezi, Xinjiang 832002, China.
authors.forename: Wen-Jie
authors.initials: WJ
authors.lastname: Zhang
authors.affiliation: Department of Nutrition and Food Hygiene, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Lie-Gang
authors.initials: LG
authors.lastname: Liu
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000328:Adult; D000368:Aged; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D006706:Homeostasis; D006801:Humans; D007333:Insulin Resistance; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis* / Q000378:metabolism; D008875:Middle Aged
chemical_list: C499918:ADIPOQ protein, human; D052242:Adiponectin; D008076:Cholesterol, HDL; D015850:Interleukin-6