title: Continuous postoperative pain control using a multiple-hole catheter after iliac bone grafting: comparison between ropivacaine and levobupivacaine.
abstract: The aim of this study was to compare the analgesic effects of ropivacaine and levobupivacaine in continuous infiltration anaesthesia delivered via a multiple-hole catheter for the purpose of postoperative analgesia after iliac bone grafting. Thirty-four patients scheduled for iliac bone grafting in the maxillofacial region participated in this study. The patients were randomized to a ropivacaine group (Ropi group) and a levobupivacaine group (Levo group). After harvesting the iliac bone for grafting, a multiple-hole catheter was placed on the periosteum of the iliac bone. When surgery was completed, continuous administration was started at 4 ml/h of 0.2% ropivacaine (Ropi group) or 0.25% levobupivacaine (Levo group). Pain was evaluated in the recovery room and at 4h after surgery, as well as at 9:00 and 18:00 on postoperative days 1, 2, and 3, using a visual analogue scale. Side effects were also recorded. No significant difference in the visual analogue scale scores at rest or in motion was observed between the two groups. In addition, there were no side effects in the two groups. Both 0.2% ropivacaine and 0.25% levobupivacaine provided comparable analgesic effects in continuous infiltration anaesthesia delivered via a multiple-hole catheter after iliac bone grafting.
authors.affiliation: Department of Dental Anaesthesiology, Tokyo Dental College, Chiba, Japan. Electronic address: kukidomehirokazu@tdc.ac.jp.
authors.forename: H
authors.initials: H
authors.lastname: Kukidome
authors.affiliation: Department of Dental Anaesthesiology, Tokyo Dental College, Chiba, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Matsuura
authors.affiliation: Department of Pharmacology, Tokyo Dental College, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kasahara
authors.affiliation: Department of Dental Anaesthesiology, Tokyo Dental College, Chiba, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ichinohe
mesh_terms: D000328:Adult; D000577:Amides / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D016025:Bone Transplantation / Q000379:methods*; D002045:Bupivacaine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002404:Catheterization / Q000379:methods; D005260:Female; D006801:Humans; D007085:Ilium / Q000637:transplantation*; D015918:Infusion Pumps, Implantable; D000077554:Levobupivacaine; D008297:Male; D059408:Pain Management / Q000379:methods*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D000077212:Ropivacaine; D016896:Treatment Outcome
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine; D000077554:Levobupivacaine; D002045:Bupivacaine
keywords: iliac bone grafting; levobupivacaine; local anaesthesia; postoperative pain; ropivacaine