title: OsteoRheumatology: a new discipline?
abstract: This review summarises recent evidence about the interaction between bone, the immune system and cartilage in disabling conditions such as osteoarthritis, rheumatoid arthritis and spondyloarthritis. These topics have been recently discussed at the 'OsteoRheumatology' conference held in Genoa in October 2014. The meeting, at its 10th edition, has been conceived to bring together distinguished international experts in the fields of rheumatic and metabolic bone diseases with the aim of discussing emerging knowledge regarding the role of the bone tissue in rheumatic diseases. Moreover, this review focuses on new treatments based on underlying the pathophysiological processes in rheumatic diseases. Although, a number of issues still remain to be clarified, it seems quite clear that in clinical practice, as well as in basic and translational research, there is a need for more knowledge of the interactions between the cartilage, the immune system and the bone. In this context, 'OsteoRheumatology' represents a potential new discipline providing a greater insight into this interplay, in order to face the multifactorial and complex issues underlying common and disabling rheumatic diseases.
authors.affiliation: Rheumatology Unit, Department of Medicine-DIMED , University Hospital of Padova , Padova , Italy ; Laboratory of Immunorheumatology and Tissue Regeneration/RAMSES , Rizzoli Orthopedic Research Institute , Bologna , Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Favero
authors.affiliation: Bone Clinic, Department of Gerontology and Musculoskeletal Sciences , Galliera Hospital , Genoa , Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Giusti
authors.affiliation: Department of Internal Medicine, Subdivision of Rheumatology , CAPHRI/NUTRIM, Maastricht University Medical Centre , Maastricht , The Netherlands & UHasselt, Belgium.
authors.forename: Piet
authors.initials: P
authors.lastname: Geusens
authors.affiliation: Hospital for Special Surgery and Weill Cornell Medical College , New York, New York , USA.
authors.forename: Steven R
authors.initials: SR
authors.lastname: Goldring
authors.affiliation: Department of Rheumatology , VU Medical Centre , Amsterdam , The Netherlands.
authors.forename: Willem
authors.initials: W
authors.lastname: Lems
authors.affiliation: Department of Internal Medicine 3 , University of Erlangen-Nuremberg , Erlangen , Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Schett
authors.affiliation: Department of Locomotor System, Division of Rheumatology , ASL3 Genovese , Genoa , Italy.
authors.forename: Gerolamo
authors.initials: G
authors.lastname: Bianchi
keywords: Osteoarthritis; Osteoporosis; Rheumatoid Arthritis; Spondyloarthritis; Treatment