title: Comparison of Anterior Segment Biometric Measurements between Pentacam HR and IOLMaster in Normal and High Myopic Eyes.
abstract: OBJECTIVE
  To compare the anterior chamber depth (ACD), keratometry (K) and astigmatism measurements taken by IOLMaster and Pentacam HR in normal and high myopic (HM) eyes.
  
  
  METHODS
  A prospective observational case series.
  
  
  METHODS
  Sixty-six normal eyes and 59 HM eyes underwent ACD, keratometry and astigmatism measurements with both devices. Axial length (AL) was measured on IOLMaster. The interdevice agreement was evaluated using the Bland-Altman analysis and paired t-test. The correlations between age and AL & ACD were analyzed. Vector analysis was used to compare astigmatism measurements.
  
  
  RESULTS
  The ACD from IOLMaster and Pentacam HR was different for the normal group (P = 0.003) but not for the HM group (P = 0.280). IOLMaster demonstrated higher steep K and mean K values than Pentacam HR for both normal and HM groups (P<0.001 for all). IOLMaster also have higher flat K values for the HM groups (P<0.001) but were statistically equivalent with Pentacam HR for the normal group (P = 0.119) IOLMaster and Pentacam HR were different in astigmatism measurements for the normal group but were statistically equivalent for the HM group. For the normal group, age was negatively correlated with AL, IOLMaster ACD and Pentacam HR ACD (r = -0.395, P = 0.001; r = -0.715, P < 0.001; r = -0.643, P < 0.001). For the HM group, age was positively correlated with AL but negatively correlated with IOLMaster ACD and Pentacam HR ACD (r = 0.377, P = 0.003; r = -0.392, P = 0.002; r = -0.616, P < 0.001).
  
  
  CONCLUSIONS
  The IOLMaster and Pentacam HR have significant difference in corneal power measurements for both normal and HM groups. The two instruments also differ in ACD and astigmatism measurement for the normal group. Therefore, a single instrument is recommended for studying longitudinal changes in anterior segment biometric measurements. Age should be considered as an influencing factor for both AL and ACD values in the normal and HM group.
authors.affiliation: The First Hospital of Shanxi Medical University, Shanxi, P.R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Dong
authors.affiliation: Casey Eye Institute, Oregon Health and Science University, Portland, Oregon, United States of America.
authors.forename: Maolong
authors.initials: M
authors.lastname: Tang
authors.affiliation: Shanxi Eye Hospital, Shanxi, P.R. China.
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Shanxi Eye Hospital, Shanxi, P.R. China.
authors.forename: Yading
authors.initials: Y
authors.lastname: Jia
authors.affiliation: Shanxi Eye Hospital, Shanxi, P.R. China.
authors.forename: Haining
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Shanxi Eye Hospital, Shanxi, P.R. China.
authors.forename: Zhijie
authors.initials: Z
authors.lastname: Jia
authors.affiliation: Shanxi Eye Hospital, Shanxi, P.R. China.
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000867:Anterior Chamber / Q000502:physiology*; D001251:Astigmatism / Q000503:physiopathology; D001699:Biometry; D003315:Cornea / Q000503:physiopathology; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology*; D011446:Prospective Studies