title: [Combined treatment in malignant tumors of the head and neck with reconstructive-plastic surgery].
abstract: The article is devoted to conservative and reconstructive-plastic surgical interventions using biocompatible implants accompanied by various types of radiotherapy and modern anticancer drugs that have allowed improving basic survival with maintaining a high level of quality of life. Our method of combined treatment for larynx, hypopharynx, oral cavity and oropharynx cancer of stage II-III by chemoradotherapy shows high immediate effectiveness and allows achieving statistically significant increase of overall and disease-free survival in the remote period of observation. The use of NiTi implants provides reliable recovery of deleted structures, pressurization of the cranial cavity, reduces the duration of surgery, shortens the time of wound healing.
authors.forename: E L
authors.initials: EL
authors.lastname: Choinzonov
authors.forename: V A
authors.initials: VA
authors.lastname: Novikov
authors.forename: M R
authors.initials: MR
authors.lastname: Mukhamedov
authors.forename: D A
authors.initials: DA
authors.lastname: Shishkin
authors.forename: S Yu
authors.initials: SY
authors.lastname: Chizhevskaya
authors.forename: V A
authors.initials: VA
authors.lastname: Syrkashev
authors.forename: V I
authors.initials: VI
authors.lastname: Shtin
authors.forename: D E
authors.initials: DE
authors.lastname: Kulbakin
mesh_terms: D000328:Adult; D000368:Aged; D001672:Biocompatible Materials / Q000627:therapeutic use*; D059186:Chemoradiotherapy, Adjuvant; D018572:Disease-Free Survival; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011788:Quality of Life; D019651:Plastic Surgery Procedures / Q000379:methods; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials