title: [Two Cases of Rapidly Progressive Community-acquired Pneumonia Due to Pseudomonas aeruginosa].
abstract: Pseudomonas aeruginosa is a significant causative bacterium in hospital-acquired pneumonia and nursing and healthcare-associated pneumonia, but it seems to be rare in community-acquired pneumonia (CAP). We report two cases of severe CAP due to P. aeruginosa. Case 1: A 52-year-old man was referred to our hospital for chest and back pain. He was being treated for diabetes mellitus and had a long history of smoking. Chest images showed consolidation in the right upper lobe. Soon after hospitalization, he developed sepsis shock and died seven hours later. Case 2: A 73-year-old man with a history of heavy smoking was referred to our hospital for right chest pain. Chest images showed right upper lobe pneumonia. Although wide-spectrum antimicrobial agents were administrated, he died ten hours after admission. In both cases, there was a rapid progression to death, despite administration of a broad spectrum of antibiotics and treatment for sepsis. In cases of CAP involving the right upper lobe, the possibility of bacteremia and rapid progress should be considered.
authors.forename: Akira
authors.initials: A
authors.lastname: Takakura
authors.forename: Ken
authors.initials: K
authors.lastname: Katono
authors.forename: Shinya
authors.initials: S
authors.lastname: Harada
authors.forename: Satoshi
authors.initials: S
authors.lastname: Igawa
authors.forename: Masato
authors.initials: M
authors.lastname: Katagiri
authors.forename: Nobuo
authors.initials: N
authors.lastname: Yanase
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Masuda
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents