title: [Effectiveness of Meibomian Gland Tube Massage in Treating Meibomian Gland Dysfunction].
abstract: OBJECTIVE
  To observe the clinical effectiveness of meibomian gland tube massage in treating meibomian gland dysfunction (MGD).
  
  
  METHODS
  All patients were divided into medicine group (tropically administered with corticosteroid eye ointment and artificial tears)and massage group (meibomian gland tube massage in addition to these drugs) using random numbers. At different period(before treatment and after treatment 2,4 weeks), the slip-lamp microscopy and intraocular pressure measurement were performed. Ocular symptoms were evaluated by questionnaire of ocular surface disease index (OSDI), and corneal fluorescein staining scores (CFS) was used for checking the epithelial integrity,tear film breakup time (TBUT), and tear secretion (Schirmer I test,SIt).
  
  
  RESULTS
  Before the treatment, the OSDI score,TBUT, CFS, and SIt showed no statistical significance between these two groups (all P>0.05). After the treatment, the symptoms, damage of corneal epithelium, quality of tear film,tear secretion were significantly improved in both groups(P<0.05), and were significantly superior in the massage group than in the medicine group (all P<0.01; but CFS t4w=6.60,P>0.05).
  
  
  CONCLUSIONS
  The meibomian gland tube massage in combination with drug therapy can improve the treatment effectives for MGD.
authors.affiliation: Department of Ophthalmology,the Second Hospital of Shandong University,Ophthalmic Center of Shandong University,Jinan 250033,China.
authors.forename: Guo-ling
authors.initials: GL
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology,the Second Hospital of Shandong University,Ophthalmic Center of Shandong University,Jinan 250033,China.
authors.forename: Xin
authors.initials: X
authors.lastname: Kao
authors.affiliation: Department of Ophthalmology,the Second Hospital of Shandong University,Ophthalmic Center of Shandong University,Jinan 250033,China.
authors.forename: Han
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Ophthalmology,the Second Hospital of Shandong University,Ophthalmic Center of Shandong University,Jinan 250033,China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Xiao
authors.affiliation: Department of Ophthalmology,the Second Hospital of Shandong University,Ophthalmic Center of Shandong University,Jinan 250033,China.
authors.forename: Shao-hua
authors.initials: SH
authors.lastname: Liu
authors.affiliation: Department of Ophthalmology,the Second Hospital of Shandong University,Ophthalmic Center of Shandong University,Jinan 250033,China.
authors.forename: Guang-feng
authors.initials: GF
authors.lastname: Ma
authors.affiliation: Department of Ophthalmology,the Second Hospital of Shandong University,Ophthalmic Center of Shandong University,Jinan 250033,China.
authors.forename: Jing
authors.initials: J
authors.lastname: Hou
mesh_terms: D003315:Cornea; D005141:Eyelid Diseases; D019793:Fluorescein; D006801:Humans; D008537:Meibomian Glands; D011795:Surveys and Questionnaires; D013666:Tears
chemical_list: D019793:Fluorescein