title: Zn-Mediated Reduction of Oxalyl Chloride Forming CO and Its Application in Carbonylation Reactions.
abstract: An efficient protocol for the generation of carbon monoxide by Zn-mediated reduction of oxalyl chloride has been developed. Oxalyl chloride was applied as an extremely effective substitute for toxic gaseous CO in the palladium-catalyzed alkoxy-/amino-/hydrogen-/hydroxycarbonylation processes providing industrially interesting esters, amides, aldehydes, and carboxylic acids in good to excellent yields. This new procedure can be applied to various carbonylation reactions in the presence of a transition metal catalyst under mild conditions and with a stoichiometric amount of CO source.
authors.affiliation: Department of Organic Chemistry, Institute of Organic Chemistry, Catalysis and Petrochemistry, Slovak University of Technology , Radlinského 9, SK-812 37 Bratislava, Slovakia.
authors.forename: Martin
authors.initials: M
authors.lastname: Markovič
authors.affiliation: Department of Organic Chemistry, Institute of Organic Chemistry, Catalysis and Petrochemistry, Slovak University of Technology , Radlinského 9, SK-812 37 Bratislava, Slovakia.
authors.forename: Pavol
authors.initials: P
authors.lastname: Lopatka
authors.affiliation: Georganics Ltd., Koreničova 1, SK-811 03 Bratislava, Slovakia.
authors.forename: Peter
authors.initials: P
authors.lastname: Koóš
authors.affiliation: Department of Organic Chemistry, Institute of Organic Chemistry, Catalysis and Petrochemistry, Slovak University of Technology , Radlinského 9, SK-812 37 Bratislava, Slovakia.
authors.forename: Tibor
authors.initials: T
authors.lastname: Gracza