title: Visit-to-visit blood pressure variability and classes of antihypertensive agents; associations with artery remodeling and the risk of stroke.
abstract: Recent studies have shown that visit-to-visit blood pressure (BP) variability was emerging as an independent risk factor for stroke. Although the mechanism is not fully understood, artery remodeling would be closely associated with the relationship between visit-to-visit BP variability and stroke. In addition, the class of antihypertensive agents is suggested to be an important determinant of visit-to-visit BP variability. This review article summarizes the recent literature on these topics. In the elderly hypertensives, strict BP control using calcium channel blockade would play a crucial role to prevent stroke via reducing the visit-to-visit BP variability.
authors.affiliation: Department of Cardiology, Hiroshima City Asa Hospital 2-1-1, Kabeminami, Aaskita-ku, Hiroshima 731-0293, JAPAN. nagai10m@r6.dion.ne.jp.
authors.forename: Michiaki
authors.initials: M
authors.lastname: Nagai
authors.forename: Keigo
authors.initials: K
authors.lastname: Dote
authors.forename: Masaya
authors.initials: M
authors.lastname: Kato
authors.forename: Shota
authors.initials: S
authors.lastname: Sasaki
authors.forename: Noboru
authors.initials: N
authors.lastname: Oda
authors.forename: Eisuke
authors.initials: E
authors.lastname: Kagawa
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Nakano
authors.forename: Aya
authors.initials: A
authors.lastname: Yamane
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Kubo
authors.forename: Tasuku
authors.initials: T
authors.lastname: Higashihara
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Miyauchi
authors.forename: Wakako
authors.initials: W
authors.lastname: Harada
mesh_terms: D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000145:classification / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects*; D001795:Blood Pressure Determination; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000145:classification / Q000627:therapeutic use; D002339:Carotid Arteries / Q000187:drug effects* / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology; D012306:Risk; D020521:Stroke / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D066253:Vascular Remodeling / Q000187:drug effects*
chemical_list: D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers