title: [A cohort study on dietary cholesterol intake and hypercholesterolemia among adults in 9 provinces and autonomous regions].
abstract: OBJECTIVE
  To explore the association between dietary cholesterol intake and hypercholesterolemia among Chinese adults.
  
  
  METHODS
  In 2009, 4 244 adults aged 25-65 years old who participated in both 2004 and 2009 China Health and Nutrition Surveys, and with complete biochemical and dietary data were selected. Hypercholesterolemia were defined as with total cholesterol ≥ 6.22 mmol/L, according to 2007 Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. Non-conditional logistic regression was used to investigate association between dietary cholesterol intake and hypercholesterolemia.
  
  
  RESULTS
  The average total cholesterol was 4.9 mmol/L, with prevalence of hypercholesterolemia as 9.6%, in 2009. During 2004 to 2009, dietary cholesterol showed a dramatical increase, with lower intake groups the most. Males who consumed middle or lower dietary cholesterol in 2004 and high intake in 2009 had significantly higher risk of having hypercholesterolemia. However, similar findings did not appear in females.
  
  
  CONCLUSIONS
  The associations between dietary cholesterol intake and hypercholesterolemia were different among Chinese males and females. Dramatic increase of dietary cholesterol intake was related to higher risk of hypercholesterolemia in males.
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Wenwen
authors.initials: W
authors.lastname: Du
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Yifei
authors.initials: Y
authors.lastname: Ouyang
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Huijun
authors.initials: H
authors.lastname: Wang
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Wang
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Chang
authors.initials: C
authors.lastname: Su
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Jiguo
authors.initials: J
authors.lastname: Zhang
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Ji
authors.initials: J
authors.lastname: Zhang
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
authors.forename: Hongru
authors.initials: H
authors.lastname: Jiang
authors.affiliation: National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China; Email: zzhangb327@aliyun.com.
authors.forename: Bing
authors.initials: B
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D002784:Cholesterol; D002791:Cholesterol, Dietary / Q000008:administration & dosage*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D015995:Prevalence; D012307:Risk Factors; D017678:Sex Distribution
chemical_list: D002791:Cholesterol, Dietary; D002784:Cholesterol