title: Anti-dandruff Hair Tonic Containing Lemongrass (Cymbopogon flexuosus) Oil.
abstract: BACKGROUND
  Natural remedies for treating dandruff are becoming popular.
  
  
  METHODS
  A randomized, double-blind, placebo-controlled, split-head efficacy evaluation was conducted 30 Thai volunteers aged 20-60 years experiencing dandruff measured at level 3 on D-Squame® scale. An easy to use hair tonic containing essential oil of lemongrass (Cymbopogon flexuosus) active against lipophilic yeasts was developed and then evaluated for efficacy and preference. The base formulation with the significantly highest preference (p < 0.05) was stowed with the oil at 5, 10 or 15%. Subjects applied the formulation twice a day, and an efficacy assessment with D-Squame® scale was conducted on days 7 and 14 of application.
  
  
  RESULTS
  The application of lemongrass oil hair tonics with 5, 10, or 15% reduced dandruff significant (p < 0.005) at day 7 (33, 75, and 51%) and increased the effect even more (p < 0.005) at day 14 (52, 81, and 74%).
  
  
  CONCLUSIONS
  The hair tonic formulation with 10% of lemongrass oil seems to be the most effective preparation.
authors.affiliation: School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand.
authors.forename: Wannee
authors.initials: W
authors.lastname: Chaisripipat
authors.forename: Nattaya
authors.initials: N
authors.lastname: Lourith
authors.forename: Mayuree
authors.initials: M
authors.lastname: Kanlayavattanakul
mesh_terms: D000328:Adult; D002626:Chemistry, Pharmaceutical; D063807:Dandruff / Q000628:therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010938:Plant Oils / Q000008:administration & dosage / Q000627:therapeutic use*; D013729:Terpenes / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D010938:Plant Oils; D013729:Terpenes; C052901:lemongrass oil