title: InterPregGen: genetic studies of pre-eclampsia in three continents.
abstract: Pre-eclampsia is a major cause of maternal and fetal mortality in pregnancy. The identification of genetic variants which predispose to pre-eclampsia demands large DNA collections from affected mothers and babies and controls, with reliable supporting phenotypic data. The InterPregGen study has assembled a consortium of researchers from Europe, Central Asia and South America with the aim of elucidating the genetic architecture of pre-eclampsia. The MoBa collection is playing a vital role in this collaborative venture, which has the potential to provide new insights into the causes of pre-eclampsia, and provide a rational basis for novel approaches to prevention and treatment.
authors.affiliation: School of Life Sciences, University of Nottingham, UK.
authors.forename: Linda
authors.initials: L
authors.lastname: Morgan
authors.affiliation: Wellcome Trust Sanger Institute, UK.
authors.forename: Ralph
authors.initials: R
authors.lastname: McGinnis
authors.affiliation: deCODE Genetics, Iceland.
authors.forename: Valgerdur
authors.initials: V
authors.lastname: Steinthorsdottir
authors.affiliation: Scientific Centre of Obstetrics, Gynaecology and Perinatology of Ministry of Health, Kazakhstan.
authors.forename: Gulnara
authors.initials: G
authors.lastname: Svyatova
authors.affiliation: Institute of Immunology, Uzbek Academy of Science, Uzbekistan.
authors.forename: Nodira
authors.initials: N
authors.lastname: Zakhidova
authors.affiliation: BHF Glasgow Cardiovascular Research Centre, University of Glasgow, UK.
authors.forename: Wai Kwong
authors.initials: WK
authors.lastname: Lee
authors.affiliation: Department of Cancer Research and Molecular Medicine and Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Norway.
authors.forename: Ann-Charlotte
authors.initials: AC
authors.lastname: Iversen
authors.affiliation: Norwegian Institute of Public Health, Norway.
authors.forename: Per
authors.initials: P
authors.lastname: Magnus
authors.affiliation: Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, UK.
authors.forename: James
authors.initials: J
authors.lastname: Walker
authors.affiliation: London School of Hygiene and Tropical Medicine and University College London, UK.
authors.forename: Juan Pablo
authors.initials: JP
authors.lastname: Casas
authors.affiliation: Republic Specialized Scientific-Practical Medical Centre of Obstetrics and Gynaecology, Uzbekistan.
authors.forename: Saidazim
authors.initials: S
authors.lastname: Sultanov
authors.affiliation: Haartman Institute, Medical Genetics, University of Helsinki, Finland.
authors.forename: Hannele
authors.initials: H
authors.lastname: Laivuori