title: Cancer therapy: know your enemy?
abstract: BACKGROUND
  Most cancer therapies are devised for adult or even elder patients. However, when dealing with pediatric cancers, additional considerations are needed.
  
  
  CONCLUSIONS
  This review discusses non-classic components of tumors and highlights possible treatment approaches which might be of particular benefit for children and adolescents.
authors.affiliation: Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Eythstrasse 24, 89075, Ulm, Germany. andrew.westhoff@uniklinik-ulm.de.
authors.forename: Mike-Andrew
authors.initials: MA
authors.lastname: Westhoff
authors.affiliation: Laboratorio Analisi Sicilia Catania, 96016, Lentini (SR), Italy. kontakt@oliverbruehl.de.
authors.forename: Oliver
authors.initials: O
authors.lastname: Brühl
authors.affiliation: Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Eythstrasse 24, 89075, Ulm, Germany. klaus-michael.debatin@uniklinik-ulm.de.
authors.forename: Klaus-Michael
authors.initials: KM
authors.lastname: Debatin
keywords: Adhesion-mediated apoptosis resistance; Tumor microenvironment; Tumor-associated macrophages