title: CRISPR sabotage.
abstract: The biological arms race generally involves the rapid co-evolution of anti-virus systems in host organisms and of anti-anti-virus systems in their viral parasites. The CRISPR-Cas system is an example of a prokaryotic immune system in which such co-evolution occurs, as was recently demonstrated by the characterization of a set of viral anti-CRISPR proteins.
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein, 6703, HB, Wageningen, The Netherlands. john.vanderoost@wur.nl.
authors.forename: John
authors.initials: J
authors.lastname: van der Oost
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein, 6703, HB, Wageningen, The Netherlands.
authors.forename: Stan J J
authors.initials: SJ
authors.lastname: Brouns
mesh_terms: D064113:CRISPR-Cas Systems / Q000235:genetics* / Q000276:immunology; D019143:Evolution, Molecular; D016679:Genome, Viral / Q000235:genetics / Q000276:immunology; D054884:Host-Pathogen Interactions / Q000235:genetics / Q000276:immunology; D006801:Humans; D034622:RNA Interference / Q000276:immunology; D014764:Viral Proteins / Q000235:genetics* / Q000276:immunology
chemical_list: D014764:Viral Proteins