title: Efficient and synergetic DNA delivery with pyridinium amphiphiles-gold nanoparticle composite systems having different packing parameters.
abstract: Mixtures of highly curved pyridinium-decorated Au nanoparticles and standard pyridinium cationic lipids efficiently and synergetically transfected DNA in vitro, while displaying an excellent cytotoxic profile.
authors.affiliation: College of Science and Technology, Temple University, 1803 N Broad Street, Philadelphia, PA-19122, USA.
authors.forename: Adrian
authors.initials: A
authors.lastname: Kizewski
authors.affiliation: Department of Pharmaceutical Sciences and Moulder Center of Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA-19140, USA. mailies@temple.edu and Temple Materials Institute, 1803 N Broad Street, Philadelphia, PA-19122, USA.
authors.forename: Marc A
authors.initials: MA
authors.lastname: Ilies
mesh_terms: D045744:Cell Line, Tumor; D004247:DNA / Q000008:administration & dosage* / Q000235:genetics; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D011726:Pyridinium Compounds / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry*; D014162:Transfection
chemical_list: D011726:Pyridinium Compounds; D013501:Surface-Active Agents; D006046:Gold; D004247:DNA