title: Resolution of P-stereogenic P-heterocycles via the formation of diastereomeric molecular and coordination complexes (a review).
abstract: TADDOL derivatives and the Ca(2+)-salts of tartaric acid derivatives were found to be versatile and generally applicable resolving agents for the preparation of the enantiomers of P-stereogenic heterocyclic phosphine oxides and phosphinates via the formation of the corresponding diastereomeric molecular and coordination complexes. A few of the diastereomeric intermediates were characterized by single crystal X-ray crystallography to gain insights into the binding mode of the corresponding heterocyclic phosphine oxide ("guest") and the resolving agent ("host") and to study the underlying phenomenon of enantiomeric recognition.
authors.affiliation: Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, 1521 Budapest, Hungary. gkeglevich@mail.bme.hu.
authors.forename: Péter
authors.initials: P
authors.lastname: Bagi
authors.forename: Viktória
authors.initials: V
authors.lastname: Ujj
authors.forename: Mátyás
authors.initials: M
authors.lastname: Czugler
authors.forename: Elemér
authors.initials: E
authors.lastname: Fogassy
authors.forename: György
authors.initials: G
authors.lastname: Keglevich
mesh_terms: D056831:Coordination Complexes / Q000737:chemistry*; D004148:Dioxolanes / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000737:chemistry*; D000432:Methanol / Q000031:analogs & derivatives / Q000737:chemistry; D017553:Phosphorus Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013644:Tartrates / Q000737:chemistry
chemical_list: D056831:Coordination Complexes; D004148:Dioxolanes; D006571:Heterocyclic Compounds; D017553:Phosphorus Compounds; D013644:Tartrates; C516101:alpha,alpha,alpha',alpha'-tetraaryl-1,3-dioxolane-4,5-dimethanol; C029768:tartaric acid; D000432:Methanol