title: The evaluation of risk factors for recurrent hospitalizations resulting from wheezing attacks in preschool children.
abstract: BACKGROUND
  We aimed to evaluate the risk factors in preschool children admitted to inpatient services with a diagnosis of recurrent attacks of wheezing.
  
  
  METHODS
  The medical files of 44 preschool children with 2 or more recurrent hospitalizations resulting from wheezing between November 2011 and January 2012 were retrospectively investigated.
  
  
  RESULTS
  There were 28 males (64 %) and 16 females. The median age was 14 months (2.0-50). The median numbers of previous wheezing attacks and hospitalizations were 4 (2-10) and 2 (2-8), respectively. Fourteen patients (32 %) had been treated for gastroesophageal reflux (GER). The previous and recent hospital evaluations were investigated. Bronchopulmonary dysplasia and anemia were significantly more common in patients with 3 or more hospitalizations for wheezing than in those with 2 hospitalizations (p = 0.010 and p < 0.001, respectively). A review of the cases with 3 or more hospitalizations revealed that a history of GER and anemia were significant risk factors.
  
  
  CONCLUSIONS
  Anemia and GER are risk factors for recurrent hospitalizations resulting from wheezing and should be treated. If the history and physical examination suggest asthma, inhaler therapy treatment should be administered, with other investigations planned for patients who do not respond to treatment as expected.
authors.affiliation: Sisli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey. Ozdogan65@hotmail.com.|Sinan Ercan Sok, Isiklar 1 Apt. No 34, Da: 23, 34742, Kozyataği, Istanbul, Turkey. Ozdogan65@hotmail.com.
authors.forename: Sebnem
authors.initials: S
authors.lastname: Ozdogan
authors.affiliation: Sisli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey. dr.bytr@hotmail.com.
authors.forename: Burcu
authors.initials: B
authors.lastname: Tabakci
authors.affiliation: Sisli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey. aysesirinaslan@hotmail.com.
authors.forename: Ayse Sirin
authors.initials: AS
authors.lastname: Demirel
authors.affiliation: Sisli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey. bilge.atl@gmail.com.
authors.forename: Bilge
authors.initials: B
authors.lastname: Atli
authors.affiliation: Istanbul Medeniyet University, Faculty of Medicine, Goztepe, Turkey. esenbesli@yahoo.com.
authors.forename: Gulser Esen
authors.initials: GE
authors.lastname: Besli
authors.affiliation: Sisli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey. Gulsenkose81@yahoo.com.
authors.forename: Gulsen
authors.initials: G
authors.lastname: Kose
mesh_terms: D000740:Anemia / Q000150:complications* / Q000628:therapy; D001999:Bronchoscopy; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000628:therapy; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D010359:Patient Readmission / Q000706:statistics & numerical data*; D013902:Radiography, Thoracic; D012008:Recurrence; D012135:Respiratory Sounds / Q000175:diagnosis / Q000209:etiology*; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D014421:Turkey / Q000453:epidemiology