title: Feruloyl glycerol and 1,3-diferuloyl glycerol antioxidant behavior in phospholipid vesicles.
abstract: Feruloyl-sn-glycerol (FG) and 1,3-diferuloyl-sn-glycerol (F2G), the by-product of biocatalytic transesterification soybean oil and ethyl ferulate, were examined for their behavior in phospholipid vesicles. Based on absorbance and fluorescence methods, FG and F2G both were found to partition into vesicles and incorporate well into 1,2-dioleoylphosphocholine (DOPC) vesicles. FG and F2G incorporation resulted in vesicles that were as or slightly more stable than the unloaded vesicles. FG and F2G both demonstrated the ability to maintain antioxidant properties within the lipid bilayer. Bilayer depth analysis was conducted using the parallax method and molecular modeling.
authors.affiliation: Renewable Products Technology Research Unit, National Center of Agricultural Utilization Research Center, Agricultural Research Service, U.S. Department of Agriculture, 1815 N. University Street, Peoria, IL 61604, USA. Electronic address: Kervin.Evans@ars.usda.gov.
authors.forename: Kervin O
authors.initials: KO
authors.lastname: Evans
authors.affiliation: Renewable Products Technology Research Unit, National Center of Agricultural Utilization Research Center, Agricultural Research Service, U.S. Department of Agriculture, 1815 N. University Street, Peoria, IL 61604, USA.
authors.forename: David L
authors.initials: DL
authors.lastname: Compton
authors.affiliation: Renewable Products Technology Research Unit, National Center of Agricultural Utilization Research Center, Agricultural Research Service, U.S. Department of Agriculture, 1815 N. University Street, Peoria, IL 61604, USA.
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Laszlo
authors.affiliation: Bacterial Foodborne Pathogens & Mycology Research Unit, National Center of Agricultural Utilization Research Center, Agricultural Research Service, U.S. Department of Agriculture, 1815 N. University Street, Peoria, IL 61604, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Appell
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000378:metabolism; D003373:Coumaric Acids / Q000737:chemistry* / Q000378:metabolism; D004075:Diglycerides / Q000737:chemistry* / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry* / Q000378:metabolism; D015227:Lipid Peroxidation; D056004:Molecular Dynamics Simulation; D050178:Monoglycerides / Q000737:chemistry* / Q000378:metabolism; D010713:Phosphatidylcholines / Q000737:chemistry; D010743:Phospholipids / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: C000611059:1,3-diferuloylglycerol; C000611058:1-feruloylglycerol; D000975:Antioxidants; D003373:Coumaric Acids; D004075:Diglycerides; D008051:Lipid Bilayers; D050178:Monoglycerides; D010713:Phosphatidylcholines; D010743:Phospholipids; C017251:1,2-oleoylphosphatidylcholine
keywords: Antioxidation; Diferuloyl glycerol; Feruloyl glycerol; Fluorescence; Vesicles