title: Overactive Performance Monitoring Resulting from Chronic Exposure to High Altitude.
abstract: BACKGROUND
  The neural mechanisms underlying the influence of chronic exposure to high altitude on performance monitoring are not clear. We investigated performance monitoring in the context of chronic exposure to high altitude.
  
  
  METHODS
  A go/no-go task was used to obtain event-related potentials (ERP). The error-related negativity (ERN), correct-related negativity (CRN), and error positivity (Pe) components were measured in high-altitude and low-altitude groups. The high-altitude group had lived at high altitude for 3 yr, but were born and raised at low altitude, whereas the low-altitude group had lived at low altitude only.
  
  
  RESULTS
  The ERN amplitudes were larger in the high-altitude group compared with the low-altitude group (-14.00 ± 8.34 μV vs. -7.82 ± 8.42 μV, respectively). Moreover, the CRN amplitudes were larger in the high-altitude group (3.51 ± 4.50 μV vs. 8.65 ± 3.23 μV, respectively). Group differences were not significant for the Pe component.
  
  
  CONCLUSIONS
  These results suggest that chronic exposure to high altitude can cause overactive performance monitoring in the high-altitude group, but the later stage of error monitoring was not influenced.
authors.affiliation: Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
authors.forename: Hailin
authors.initials: H
authors.lastname: Ma
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Jianhui
authors.initials: J
authors.lastname: Wu
authors.forename: Hailan
authors.initials: H
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Luo
authors.forename: Buxin
authors.initials: B
authors.lastname: Han
mesh_terms: D000328:Adult; D000531:Altitude; D001921:Brain / Q000502:physiology; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology*; D012111:Residence Characteristics; D055815:Young Adult