title: Intestinal Current Measurements Detect Activation of Mutant CFTR in Patients with Cystic Fibrosis with the G551D Mutation Treated with Ivacaftor.
authors.affiliation: 1 University of Heidelberg Heidelberg, Germany.|6 German Center for Lung Research (DZL).
authors.forename: Simon Y
authors.initials: SY
authors.lastname: Graeber
authors.affiliation: 2 University Medical Center Freiburg Freiburg, Germany.
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Hug
authors.affiliation: 1 University of Heidelberg Heidelberg, Germany.
authors.forename: Olaf
authors.initials: O
authors.lastname: Sommerburg
authors.affiliation: 1 University of Heidelberg Heidelberg, Germany.|6 German Center for Lung Research (DZL).
authors.forename: Stephanie
authors.initials: S
authors.lastname: Hirtz
authors.affiliation: 3 Jena University Hospital Jena, Germany.
authors.forename: Julia
authors.initials: J
authors.lastname: Hentschel
authors.affiliation: 4 University of Freiburg Freiburg, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Heinzmann
authors.affiliation: 5 Hannover Medical School Hannover, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Dopfer
authors.affiliation: 5 Hannover Medical School Hannover, Germany.|6 German Center for Lung Research (DZL).
authors.forename: Angela
authors.initials: A
authors.lastname: Schulz
authors.affiliation: 3 Jena University Hospital Jena, Germany.
authors.forename: Jochen G
authors.initials: JG
authors.lastname: Mainz
authors.affiliation: 5 Hannover Medical School Hannover, Germany.|6 German Center for Lung Research (DZL).
authors.forename: Burkhard
authors.initials: B
authors.lastname: Tümmler
authors.affiliation: 1 University of Heidelberg Heidelberg, Germany.|6 German Center for Lung Research (DZL).
authors.forename: Marcus A
authors.initials: MA
authors.lastname: Mall
mesh_terms: D000293:Adolescent; D000627:Aminophenols / Q000627:therapeutic use*; D003550:Cystic Fibrosis / Q000188:drug therapy* / Q000235:genetics*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000187:drug effects* / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D009154:Mutation / Q000187:drug effects / Q000235:genetics; D057285:Precision Medicine / Q000379:methods; D015363:Quinolones / Q000627:therapeutic use*
chemical_list: D000627:Aminophenols; C505032:CFTR protein, human; D015363:Quinolones; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; C545203:ivacaftor