title: Out of the Mouth of Minnows.
abstract: The skeleton articulates at specialized junctions, or joints. Although many factors that specify joints are known, how these different mechanisms are integrated to define the joint remains unclear. In this issue of Developmental Cell, Askary et al. (2015) utilize zebrafish to identify genetic regulatory mechanisms of joint specification and differentiation.
authors.affiliation: Department of Genetics, Harvard Medical School, Orthopaedic Research Laboratories, Boston Children's Hospital, 300 Longwood Avenue Enders 260, Mail Stop 3096, Boston, MA 02115, USA. Electronic address: harris@genetics.med.harvard.edu.
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Harris
authors.affiliation: Department of Genetics, Harvard Medical School, Orthopaedic Research Laboratories, Boston Children's Hospital, 300 Longwood Avenue Enders 260, Mail Stop 3096, Boston, MA 02115, USA; Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA.
authors.forename: M Brent
authors.initials: MB
authors.lastname: Hawkins
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D002358:Cartilage, Articular / Q000378:metabolism*; D002454:Cell Differentiation / Q000502:physiology*; D019902:Chondrocytes / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism*; D015027:Zebrafish / Q000378:metabolism*
chemical_list: D014157:Transcription Factors