title: Candida albicans pancreatitis in a child with cystic fibrosis post lung transplantation.
abstract: We present a case of Candida albicans infection of a previously intact pancreas in a child with cystic fibrosis status post lung transplantation. Although Candida superinfection in necrotizing pancreatitis is not uncommon, this is a unique case of Candida infection of non-necrotic pancreatic parenchyma. This case presented a diagnostic dilemma for radiologists because it appeared virtually identical to acute interstitial edematous pancreatitis on imaging. Ultimately, endoscopic US-based biopsy was pursued for diagnosis. Although difficult to treat and compounded by the immunocompromised status of the child, the pancreatic infection improved with antifungal therapy.
authors.affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd., Campus Box 8131, St. Louis, MO, 63110, USA.
authors.forename: Mark M
authors.initials: MM
authors.lastname: Hammer
authors.affiliation: Department of Pathology, Washington University School of Medicine, St. Louis, MO, USA.
authors.forename: Lingxin
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Division of Gastroenterology, Hepatology and Nutrition, Washington University School of Medicine, St. Louis, MO, USA.
authors.forename: Janis M
authors.initials: JM
authors.lastname: Stoll
authors.affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd., Campus Box 8131, St. Louis, MO, 63110, USA. elizabeth.sheybani@gmail.com.
authors.forename: Elizabeth F
authors.initials: EF
authors.lastname: Sheybani
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000209:etiology* / Q000473:pathology*; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications / Q000601:surgery*; D003937:Diagnosis, Differential; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects*; D010195:Pancreatitis / Q000209:etiology* / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents
keywords: Candida albicans; Child; Cystic fibrosis; Fungus; Infection; Magnetic resonance imaging; Pancreas; Pancreatitis; Positron emission tomography