title: Enhanced sensing performance of supported graphitic carbon nitride nanosheets and the fabrication of electrochemiluminescent biosensors for IgG.
abstract: The key challenge for fabricating electrogenerated chemiluminescence (ECL) biosensors still lies in the improvement of the sensing performance of ECL luminophores. Graphite-like carbon nitride (g-C3N4) nanosheets were prepared and the cathodic ECL performance was investigated. The ECL emission of g-C3N4 nanosheets was greatly enhanced and higher sensing sensitivity towards copper ions was achieved by a "space effect", the incorporation of g-C3N4 nanosheets into a top-down prepared nanoporous matrix. Label-free ECL immunosensors were fabricated based on this simple sensing platform. The unique signal amplification strategy and simple fabrication procedure guarantee the sensor stability and production reproducibility. Nanoporous matrix supported ECL probes have potential as a versatile sensing strategy for the fabrication of ECL biosensors.
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. sdjndxwq@163.com.
authors.forename: Xiaojian
authors.initials: X
authors.lastname: Li
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. sdjndxwq@163.com.
authors.forename: Hongmin
authors.initials: H
authors.lastname: Ma
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. sdjndxwq@163.com.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. sdjndxwq@163.com.
authors.forename: Dan
authors.initials: D
authors.lastname: Wu
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. sdjndxwq@163.com.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Lv
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. sdjndxwq@163.com.
authors.forename: Bin
authors.initials: B
authors.lastname: Du
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. sdjndxwq@163.com.
authors.forename: Qin
authors.initials: Q
authors.lastname: Wei
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation* / Q000379:methods*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis* / Q000737:chemistry; D057230:Limit of Detection; D046529:Microscopy, Electron, Transmission; D049329:Nanostructures / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D012815:Signal Processing, Computer-Assisted; D014867:Water / Q000737:chemistry
chemical_list: D007074:Immunoglobulin G; D009570:Nitriles; D014867:Water; C011206:cyanogen; D006108:Graphite