title: Harnessing the alarmin HMGN1 for anticancer therapy.
authors.affiliation: Laboratory of Molecular Immunoregulation, Cancer & Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA.
authors.forename: De
authors.initials: D
authors.lastname: Yang
authors.affiliation: Protein Section, Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute at Bethesda, Bethesda, MD 20892, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Bustin
authors.affiliation: Laboratory of Molecular Immunoregulation, Cancer & Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702, USA.
authors.forename: Joost J
authors.initials: JJ
authors.lastname: Oppenheim
mesh_terms: D000067531:Alarmins / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003713:Dendritic Cells / Q000502:physiology*; D015972:Gene Expression Regulation, Neoplastic; D024241:HMGN1 Protein / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D056747:Immunomodulation; D008213:Lymphocyte Activation; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy; D018417:Th1 Cells / Q000276:immunology*; D059016:Tumor Microenvironment
chemical_list: D000067531:Alarmins; D024241:HMGN1 Protein
keywords: G protein-coupled receptor; HMG protein; HMGN1; TLR4; alarmin; antitumor immunity; cancer therapy; chromatin modification; dendritic cell; gene regulation