title: [Epidemiological survey of high-risk human papillomavirus among 2501 woman].
abstract: OBJECTIVE
  To survey the prevalence of high-risk human papillomavirus (HPV) in woman in Guangzhou during the period from 2013 to 2014.
  
  
  METHODS
  A total of 2501 women in Guangzhou seeking medical attention in our hospital underwent high-risk HPV genotype screening of cervical specimens using real-time PCR.
  
  
  RESULTS
  The prevalence of high-risk HPV infection among the women was 14.85% (146/983) in the year 2013, similar to the rate of 14.56% (221/1518) in 2014 (Χ(2)=0.041, P=0.839); no significant differences were found in the high-risk HPV infection rates between different age groups in either 2013 (Χ(2)=2.916, P=0.572) or 2014 (Χ(2)=6.494, P=0.165). The constituent ratio of the 13 types of high-risk HPV showed no significant difference between 2013 and 2014 (Χ(2)=11.872, P=0.452). The 13 HPV genotypes detected, listed in a descending order of the constituent ratios, included HPV-52, -16, -58, -56, -39, -51, -68, -59, -31, -35, -18, -33 and -45 in 2013, and were HPV-52, -16, -58, -68, -18, -51, -56, -39, -31, -33, -59, -35 and-45 in 2014.
  
  
  CONCLUSIONS
  We report a high prevalence of high-risk HPV among women in Guangzhou, which suggests the necessity of screening for high-risk HPV-DNA among women at all ages for prevention and early detection of cervical cancer.
authors.affiliation: Department of Laboratory Medicine, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, China. E-mail: yxchenjingna@163.com.
authors.forename: Jing-Na
authors.initials: JN
authors.lastname: Chen
authors.forename: Li-Dan
authors.initials: LD
authors.lastname: Chen
authors.forename: Wei-Yun
authors.initials: WY
authors.lastname: Zhang
authors.forename: Yong-Quan
authors.initials: YQ
authors.lastname: Yang
authors.forename: Rong-Zhi
authors.initials: RZ
authors.lastname: Tang
authors.forename: Zhao-Hui
authors.initials: ZH
authors.lastname: Sun
authors.forename: Lin-Hai
authors.initials: LH
authors.lastname: Li
mesh_terms: D002681:China / Q000453:epidemiology; D005260:Female; D005838:Genotype; D006801:Humans; D027383:Papillomaviridae / Q000145:classification / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology; D015995:Prevalence; D060888:Real-Time Polymerase Chain Reaction; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000821:virology