title: Chemical Composition and Medicinal Value of Fruiting Bodies and Submerged Cultured Mycelia of Caterpillar Medicinal Fungus Cordyceps militaris CBS-132098 (Ascomycetes).
abstract: In this paper, we report the results of a proximate analysis (i.e., moisture, ash, protein, fat, carbohydrates, and energy); a bioactive compounds analysis (i.e., cordycepin and ergothioneine); fatty and amino acid analysis; and analyses of vitamin content, macro- and microelement composition of fruiting body (FB), and mycelial biomass (MB) of medicinal caterpillar fungus Cordyceps militaris strain CBS-132098. These results demonstrate that the FB and MB of C. militaris are good sources of proteins: 59.8% protein content in the FB and 39.5% in the MB. The MB was distinguished by its carbohydrate content (39.6%), which was higher than that of the FB (29.1% carbohydrate). In the FB of C. militaris, the total amino acid content was 57.39 mg/g and in the MB it was 24.98 mg/g. The quantification of the identified fatty acids indicated that palmitic acid, oleic acid, linoleic acid, and linolenic acid were the major fatty acids. The micro- and macroelement compositions were studied. The highest results were calcium (797 mg/kg FB; 11 mg/kg MB); potassium (15,938 mg/kg FB 12,183 mg/kg MB); magnesium (4,227 mg/kg FB; 3,414 mg/kg MB); sodium (171 mg/kg FB; 1,567 mg/kg MB); phosphorus (7,196 mg/kg FB; 14,293 mg/kg MB); and sulfur (5,088 mg/kg FB; 2,558 mg/kg MB). The vitamin composition was studied, and the most abundant vitamins were vitamin A, vitamin B3, and vitamin E. The bioactive components were cordycepin, cordycepic acid (D-mannitol), and ergothioneine. There were differences in cordycepin and ergothioneine contents between the FB and the MB. The cordycepin concentration was 0.11% in the FB and 0.182% in the MB, the cordycepic acid was 4.7 mg/100g in the FB and 5.2 mg/100 g in the MB, and the ergothioneine content was 782.37 mg/kg in the FB and 130.65 mg/kg in the MB. The nutritional values of the FB and the MB of C. militaris detected indicate its potential use in well-balanced diets and sources of bioactive compounds.
authors.affiliation: Phyto Pharma Ltd., Singapore.
authors.forename: Jannie Siew Lee
authors.initials: JS
authors.lastname: Chan
authors.affiliation: Institute of Evolution and Department of Evolutionary & Environmental Biology, Faculty of Natural Sciences, University of Haifa, Mt. Carmel, Haifa 31905, Israel.
authors.forename: Gayane S
authors.initials: GS
authors.lastname: Barseghyan
authors.affiliation: Department of Evolutionary and Environmental Biology, Faculty of Natural Sciences & Institute of Evolution, University of Haifa; Department of Anatomy and Cell Biology, Faculty of Medicine, Technion, Haifa; Agricultural University of Georgia, Tbilisi.
authors.forename: Mikheil D
authors.initials: MD
authors.lastname: Asatiani
authors.affiliation: International Centre for Cryptogamic Plants and Fungi, Institute of Evolution, University of Haifa, Mt. Carmel, Haifa, Israel; and N.G. Kholodny Institute of Botany, National Academy of Sciences of Ukraine, Kiev, Ukraine.
authors.forename: Solomon P
authors.initials: SP
authors.lastname: Wasser
mesh_terms: D000596:Amino Acids / Q000032:analysis; D032661:Cordyceps / Q000737:chemistry*; D005227:Fatty Acids / Q000032:analysis; D048690:Fruiting Bodies, Fungal / Q000737:chemistry*; D025282:Mycelium / Q000737:chemistry*; D014815:Vitamins / Q000032:analysis
chemical_list: D000596:Amino Acids; D005227:Fatty Acids; D014815:Vitamins