title: [Experience with the use of palonosetron (onicit) in patients with solid tumors receiving cytostatic therapy].
abstract: Nausea and vomiting are among adverse effects of chemotherapy that significantly worsen quality of life of patients. 5-HT3 receptor antagonists have been used in recent decades to prevent and arrest these complications. Palonosetron is the most modern drug in this group. Palonosetron application during highly and moderately emetogenic chemotherapy showed its high effectiveness for nausea and vomiting prevention.
authors.forename: L Yu
authors.initials: LY
authors.lastname: Vladimirova
authors.forename: I S
authors.initials: IS
authors.lastname: Mitashok
authors.forename: A E
authors.initials: AE
authors.lastname: Storozhakova
authors.forename: E A
authors.initials: EA
authors.lastname: Kalabanova
authors.forename: Ya V
authors.initials: YV
authors.lastname: Svetitskaya
authors.forename: S N
authors.initials: SN
authors.lastname: Kabanov
mesh_terms: D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007546:Isoquinolines / Q000627:therapeutic use*; D009325:Nausea / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control*; D009369:Neoplasms / Q000188:drug therapy; D000077924:Palonosetron; D011812:Quinuclidines / Q000627:therapeutic use*; D058831:Serotonin 5-HT3 Receptor Antagonists / Q000627:therapeutic use*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014839:Vomiting / Q000139:chemically induced / Q000188:drug therapy / Q000517:prevention & control*
chemical_list: D000932:Antiemetics; D000970:Antineoplastic Agents; D007546:Isoquinolines; D011812:Quinuclidines; D058831:Serotonin 5-HT3 Receptor Antagonists; D000077924:Palonosetron