title: Hypoallergenic molecules for subcutaneous immunotherapy.
abstract: Although a large part of the population suffers from allergies, a cure is not yet available. Allergen-specific immunotherapy (AIT) offers promise for these patients. AIT has proven successful in insect and venom allergies; however, for food allergy this is still unclear. In this editorial we focus on the recent advances in a proof of concept study in food allergy, FAST (Food allergy specific immunotherapy), which may increase interest within the biomolecular and pharmaceutical industry to embark on similar projects of immunology driven precision medicine within the allergy field.
authors.affiliation: a Department of Experimental Immunology , Academic Medical Center , Amsterdam , The Netherlands.
authors.forename: Laurian
authors.initials: L
authors.lastname: Jongejan
authors.affiliation: a Department of Experimental Immunology , Academic Medical Center , Amsterdam , The Netherlands.|b Department of Otorhinolaryngology , Academic Medical Center , Amsterdam , The Netherlands.
authors.forename: Ronald
authors.initials: R
authors.lastname: van Ree
authors.affiliation: b Department of Otorhinolaryngology , Academic Medical Center , Amsterdam , The Netherlands.
authors.forename: Lars K
authors.initials: LK
authors.lastname: Poulsen
mesh_terms: D000485:Allergens / Q000276:immunology; D000818:Animals; D003888:Desensitization, Immunologic; D029941:Fish Proteins / Q000276:immunology; D005502:Food; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology / Q000628:therapy*; D007279:Injections, Subcutaneous; D014688:Venoms / Q000276:immunology
chemical_list: D000485:Allergens; D029941:Fish Proteins; D014688:Venoms
keywords: FAST; allergy; fish; hypoallergen; immunotherapy; parvalbumin; peach