title: Sequential brief neuropsychological evaluation of migraineurs is identical to controls.
abstract: BACKGROUND
  Evidence of attack-related cognitive dysfunction in migraine is growing. Controversy exists on whether cognitive dysfunction, mainly executive, may persist between attacks. Measuring the impact of cognitive function is gaining importance in clinical and research settings in migraine.
  
  
  OBJECTIVE
  To compare the performance of interictal migraine patients to controls in an assembled neuropsychological battery focused on executive functions and to study the practice effect of its repeated applications.
  
  
  METHODS
  Assembly of the battery that was then applied twice within 6 weeks to interictal migraineurs and matched healthy controls.
  
  
  RESULTS
  Migraine patients (n = 24) and controls (n = 24) had similar performance in both applications of the battery. There was a slight practice effect between the first and second evaluation, significant in Stroop Interference test (P = 0.002, multiplicity corrected); a meaningful score change was determined for each raw test scores.
  
  
  CONCLUSIONS
  Interictal migraineurs and controls performance is identical in a brief cognitive battery focused on executive functions. Repeated applications produced a practice effect that was quantified.
authors.affiliation: Department of Clinical Neurosciences, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.|Headache Center, Hospital da Luz, Lisboa, Portugal.
authors.forename: R
authors.initials: R
authors.lastname: Gil-Gouveia
authors.affiliation: Pharmacy Department, Universidade Federal do Rio Grande do Norte, Petrópolis, Brasil.
authors.forename: A G
authors.initials: AG
authors.lastname: Oliveira
authors.affiliation: Department of Clinical Neurosciences, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
authors.forename: I P
authors.initials: IP
authors.lastname: Martins
mesh_terms: D000328:Adult; D060825:Cognitive Dysfunction / Q000209:etiology / Q000503:physiopathology*; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications / Q000503:physiopathology*; D009483:Neuropsychological Tests; D055815:Young Adult
keywords: cognitive symptoms; executive dysfunction; migraine; neuropsychological testing; practice effect