title: QCM-D study of nanoparticle interactions.
abstract: Quartz crystal microbalance with dissipation monitoring (QCM-D) has been proven to be a powerful research tool to investigate in situ interactions between nanoparticles and different functionalized surfaces in liquids. QCM-D can also be used to quantitatively determine adsorption kinetics of polymers, DNA and proteins from solutions on various substrate surfaces while providing insights into conformations of adsorbed molecules. This review aims to provide a comprehensive overview on various important applications of QCM-D, focusing on deposition of nanoparticles and attachment-detachment of nanoparticles on model membranes in complex fluid systems. We will first describe the working principle of QCM-D and DLVO theory pertinent to understanding nanoparticle deposition phenomena. The interactions between different nanoparticles and functionalized surfaces for different application areas are then critically reviewed. Finally, the potential applications of QCM-D in other important fields are proposed and knowledge gaps are identified.
authors.affiliation: Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China; Beijing Key Lab of Fine Ceramics, Tsinghua University, Beijing 100084, China.
authors.forename: Shengming
authors.initials: S
authors.lastname: Xu
authors.affiliation: Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 1H9, Canada.
authors.forename: Qingxia
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 1H9, Canada.
authors.forename: Jacob
authors.initials: J
authors.lastname: Masliyah
authors.affiliation: Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China; Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB T6G 1H9, Canada. Electronic address: zhenghe.xu@ualberta.ca.
authors.forename: Zhenghe
authors.initials: Z
authors.lastname: Xu
keywords: Classic and extend DLVO theory; Nanoparticle deposition and detachment; QCM-D sensors; Quartz crystal microbalance with dissipation monitoring (QCM-D)