title: Accuracy and usefulness of noninvasive fractional flow reserve from computed tomographic coronary angiography: comparison with myocardial perfusion imaging, echocardiographic coronary flow reserve, and invasive fractional flow reserve.
abstract: We present a case of coronary artery disease with intermediate stenosis in the proximal left anterior descending artery, which was evaluated using multiple functional modalities. FFRCTdemonstrated a significant perfusion abnormality in the LAD, and the value of FFRCT(0.68) was similar to the value measured by invasive FFR (0.67). However, the other modalities gave discrepant results. In particular, perfusion scintigraphy with thallium showed no evidence of an inducible perfusion abnormality in the LAD territory. The patient was treated by PCI for two tandem lesions in the LAD. FFRCTmay have potential as a default noninvasive method for assessment of coronary anatomy and physiology.
authors.affiliation: Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Kumamoto, Saiseikai Kumamoto Hospital, 5-3-1 Chikami, Minami-ku, Kumamoto, 861-4193, Japan. eiji-taguchi@saiseikaikumamoto.jp.
authors.forename: Eiji
authors.initials: E
authors.lastname: Taguchi
authors.affiliation: Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Kumamoto, Saiseikai Kumamoto Hospital, 5-3-1 Chikami, Minami-ku, Kumamoto, 861-4193, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Nakao
authors.affiliation: Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Kumamoto, Saiseikai Kumamoto Hospital, 5-3-1 Chikami, Minami-ku, Kumamoto, 861-4193, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Hirakawa
authors.affiliation: Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Kumamoto, Saiseikai Kumamoto Hospital, 5-3-1 Chikami, Minami-ku, Kumamoto, 861-4193, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Fukunaga
authors.affiliation: Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Kumamoto, Saiseikai Kumamoto Hospital, 5-3-1 Chikami, Minami-ku, Kumamoto, 861-4193, Japan.
authors.forename: Shinzo
authors.initials: S
authors.lastname: Miyamoto
authors.affiliation: Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Kumamoto, Saiseikai Kumamoto Hospital, 5-3-1 Chikami, Minami-ku, Kumamoto, 861-4193, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Sakamoto
mesh_terms: D000368:Aged; D000072226:Computed Tomography Angiography / Q000379:methods*; D017023:Coronary Angiography / Q000379:methods*; D023921:Coronary Stenosis / Q000175:diagnosis*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D053805:Fractional Flow Reserve, Myocardial / Q000502:physiology*; D006801:Humans; D008297:Male; D055414:Myocardial Perfusion Imaging / Q000379:methods*; D015203:Reproducibility of Results; D012720:Severity of Illness Index
keywords: Computed tomography-derived computed fractional flow reserve; Invasively measured FFR