title: MALDI MS analysis, disk diffusion and optical density measurements for the antimicrobial effect of zinc oxide nanorods integrated in graphene oxide nanostructures.
abstract: Graphene oxide-zinc oxide hybrid nanostructures were synthesized and they demonstrated significant and promising antimicrobial activity on pathogenic bacteria. The combination of graphene oxide with zinc oxide nanorods showed an impressive antibacterial effect under intense scrutiny as compared with individual graphene oxide or zinc oxide nanomaterials. The characterization and investigation of GO-ZnO nanorod hybrid nanostructures were conducted using UV, FTIR, XRD, SEM, EDX and TEM measurements. The antimicrobial activity of the above hybrid material was evaluated by various methods including MALDI-MS analysis, a disk diffusion assay and optical density measurements.
authors.affiliation: Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan. hwu@faculty.nsysu.edu.tw.
authors.forename: Mukesh Lavkush
authors.initials: ML
authors.lastname: Bhaisare
authors.affiliation: Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan. hwu@faculty.nsysu.edu.tw.
authors.forename: Bo-Sgum
authors.initials: BS
authors.lastname: Wu
authors.affiliation: Department of Applied Physics and Chemistry, University of Taipei, Taipei, 10048, Taiwan.
authors.forename: Mon-Chun
authors.initials: MC
authors.lastname: Wu
authors.affiliation: Doctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University and Academia Sinica, Kaohsiung, 80424, Taiwan.
authors.forename: M Shahnawaz
authors.initials: MS
authors.lastname: Khan
authors.affiliation: Department of Applied Physics and Chemistry, University of Taipei, Taipei, 10048, Taiwan.
authors.forename: Mei-Hwei
authors.initials: MH
authors.lastname: Tseng
authors.affiliation: Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, 80424, Taiwan. hwu@faculty.nsysu.edu.tw and Doctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University and Academia Sinica, Kaohsiung, 80424, Taiwan.
authors.forename: Hui-Fen
authors.initials: HF
authors.lastname: Wu
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D004058:Diffusion; D006108:Graphite / Q000737:chemistry* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology; D043942:Nanotubes / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction; D015034:Zinc Oxide / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D006108:Graphite; D015034:Zinc Oxide