title: Intramolecular, Pd/Cu-Co-catalyzed P-C Bond Cleavage and Addition onto an Alkyne: A Route to Benzophospholes.
abstract: Under Pd(II)/CuI cocatalysis, o-diarylphosphinophenylalkynes cyclize in boiling toluene via C-P bond cleavage and arylphosphination of the C≡C bond. This protocol provides an unprecedented atom- and step-efficient access to optoelectronically and biologically interesting benzophospholes.
authors.affiliation: College of Chemistry and Molecular Engineering, International Phosphorus Laboratory, International Joint Research Laboratory for Functional Organophosphorus Materials of Henan Province, Zhengzhou University , Zhengzhou 450001, P.R. China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: College of Chemistry and Molecular Engineering, International Phosphorus Laboratory, International Joint Research Laboratory for Functional Organophosphorus Materials of Henan Province, Zhengzhou University , Zhengzhou 450001, P.R. China.
authors.forename: Zhenjie
authors.initials: Z
authors.lastname: Gan
authors.affiliation: College of Chemistry and Molecular Engineering, International Phosphorus Laboratory, International Joint Research Laboratory for Functional Organophosphorus Materials of Henan Province, Zhengzhou University , Zhengzhou 450001, P.R. China.
authors.forename: Bo
authors.initials: B
authors.lastname: Su
authors.affiliation: College of Chemistry and Molecular Engineering, International Phosphorus Laboratory, International Joint Research Laboratory for Functional Organophosphorus Materials of Henan Province, Zhengzhou University , Zhengzhou 450001, P.R. China.
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.affiliation: College of Chemistry and Molecular Engineering, International Phosphorus Laboratory, International Joint Research Laboratory for Functional Organophosphorus Materials of Henan Province, Zhengzhou University , Zhengzhou 450001, P.R. China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Duan
authors.affiliation: College of Chemistry and Molecular Engineering, International Phosphorus Laboratory, International Joint Research Laboratory for Functional Organophosphorus Materials of Henan Province, Zhengzhou University , Zhengzhou 450001, P.R. China.|Nanyang Technological University , Division of Chemistry & Biological Chemistry, 21 Nanyang Link, Singapore 637371.
authors.forename: François
authors.initials: F
authors.lastname: Mathey
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D007454:Iodides / Q000737:chemistry; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001555:Benzene Derivatives; D007454:Iodides; D009943:Organophosphorus Compounds; D010165:Palladium; D003300:Copper; C073870:cuprous iodide