title: Sequential Multicomponent Reactions and a Cu-Mediated Rearrangement: Diastereoselective Synthesis of Tricyclic Ketones.
abstract: A novel Cu-mediated rearrangement reaction based on bisamides containing a thiazolidine substructure opens the possibility for diastereoselective synthesis toward a tricyclic annulated and bridged heterocyclic system. The required precursors are easily synthesizable by a two-step synthetic pathway using the concept of sequential multicomponent reactions, i.e. the Asinger and Ugi reactions. Due to this synthesis strategy, a number of unique tricyclic heterocycles, characterized by high diversity, are synthesized in an effective manner.
authors.affiliation: Carl von Ossietzky Universität Oldenburg, Fakultät für Mathematik und Naturwissenschaften, Institut für Chemie, Carl-von-Ossietzky-Str. 9-11, 26129 Oldenburg, Germany.
authors.forename: Denis
authors.initials: D
authors.lastname: Kröger
authors.affiliation: Carl von Ossietzky Universität Oldenburg, Fakultät für Mathematik und Naturwissenschaften, Institut für Chemie, Carl-von-Ossietzky-Str. 9-11, 26129 Oldenburg, Germany.
authors.forename: Max
authors.initials: M
authors.lastname: Franz
authors.affiliation: Carl von Ossietzky Universität Oldenburg, Fakultät für Mathematik und Naturwissenschaften, Institut für Chemie, Carl-von-Ossietzky-Str. 9-11, 26129 Oldenburg, Germany.
authors.forename: Marc
authors.initials: M
authors.lastname: Schmidtmann
authors.affiliation: Carl von Ossietzky Universität Oldenburg, Fakultät für Mathematik und Naturwissenschaften, Institut für Chemie, Carl-von-Ossietzky-Str. 9-11, 26129 Oldenburg, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Martens