title: Aspirin resistance and other aspirin-related concerns.
abstract: Aspirin is a widely used medication and has become a cornerstone for treating cardiovascular disease. Aspirin can significantly reduce the incidence of cardiovascular ischemic events, recurrence and mortality, thereby improving the long-term prognosis of patients. However, there has been a staggering increase in the volume of literature addressing the issue of so-called "aspirin resistance" in recent years, and for some patients, it is difficult to avoid adverse reactions to aspirin. In this review, we present both the historical aspects of aspirin use and contemporary developments in its clinical use.
authors.affiliation: Department of Neurology and Institute of Neurology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China.
authors.forename: Gaoyu
authors.initials: G
authors.lastname: Cai
authors.affiliation: Department of Emergency, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China.
authors.forename: Weijun
authors.initials: W
authors.lastname: Zhou
authors.affiliation: Shanghai Wusong Street Community Health Service Center, Shanghai, 200940, China.
authors.forename: Ya
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Department of Emergency, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China.
authors.forename: Peili
authors.initials: P
authors.lastname: Chen
authors.affiliation: Department of Neurology and Institute of Neurology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China.
authors.forename: Zhongjiao
authors.initials: Z
authors.lastname: Lu
authors.affiliation: Department of Neurology and Institute of Neurology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China. fuyiki@sina.com.
authors.forename: Yi
authors.initials: Y
authors.lastname: Fu
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use*; D001241:Aspirin / Q000009:adverse effects* / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000517:prevention & control; D004351:Drug Resistance; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control; D012307:Risk Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin
keywords: Adverse effects; Aspirin; Clinical use; Resistance phenomenon