title: MRSA in Croatia: prevalence and management.
abstract: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are associated with increased morbidity, mortality and length of hospital stay. MRSA is a major pathogen in hospitals and an important pathogen in community infections with few severe and fatal cases. However, MRSA causes the majority of skin and soft tissue infections in the US. The burden of community MRSA is much smaller in Europe, but there are reports of livestock-associated MRSA (LA-MRSA) isolated from pigs and cattle causing significant infections in the people who are connected to these farms. MRSA has been present in Croatia for more than 45 years, and it exerts a different impact on health-care infections. A remarkable increase in MRSA percentage was noted in primarily sterile samples in 2002 (37%) in comparison to 2001 (31%). This percentage remained quite high until 2008, when the first signs of a reduced trend were observed. The lowest percentage was 22% in 2012.
authors.affiliation: a Department of Clinical and Molecular Microbiology , University Hospital Centre Zagreb , Zagreb , Croatia.
authors.forename: Ana
authors.initials: A
authors.lastname: Budimir
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology; D002417:Cattle; D017523:Croatia / Q000453:epidemiology; D017576:Daptomycin / Q000627:therapeutic use; D006801:Humans; D000069349:Linezolid / Q000627:therapeutic use; D058751:Livestock; D055624:Methicillin-Resistant Staphylococcus aureus; D008911:Minocycline / Q000031:analogs & derivatives / Q000627:therapeutic use; D015995:Prevalence; D018461:Soft Tissue Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D013207:Staphylococcal Skin Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D013552:Swine; D017334:Teicoplanin / Q000627:therapeutic use; D000078304:Tigecycline; D014640:Vancomycin / Q000627:therapeutic use; D015047:Zoonoses / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D017334:Teicoplanin; D014640:Vancomycin; D000078304:Tigecycline; D008911:Minocycline; D000069349:Linezolid; D017576:Daptomycin
keywords: MRSA; prevalence; primarily sterile samples; resistance; treatment