title: Improved predictive ability of the Montreal Cognitive Assessment for diagnosing dementia in a community-based study.
abstract: BACKGROUND
  We compared the predictive ability of the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) to diagnose dementia in a community-based study.
  
  
  METHODS
  A total of 276 people aged 60 years or older were enrolled. All of the participants were administered face-to-face interview questionnaires and MoCA and MMSE examinations. The receiver operating characteristic curve method and area under curve were performed to assess the predictive ability for diagnosing dementia.
  
  
  RESULTS
  The 276 participants had a mean age of 67.9 ± 6.1 years and mean education duration of 11.4 ± 4.0 years. In general, the MoCA yielded higher AUCs (0.891) with favorable sensitivity (78 %) and excellent specificity (94 %) compared with the MMSE in differentiating the participants with and without dementia in either the total sample or all subgroups.
  
  
  CONCLUSIONS
  Our study determined a higher predictive ability in the MoCA than in the MMSE for diagnosing dementia according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria in a community-based sample with a broader range of education level.
authors.affiliation: Graduate Institute of Humanities in Medicine, Taipei Medical University, Taipei, Taiwan. tulu@ms36.hinet.net.|Brain and Consciousness Research Center, Taipei Medical University, Shuang Ho Hospital, New Taipei City, Taiwan. tulu@ms36.hinet.net.|Section of Dementia and Cognitive Impairment, Department of Neurology, Chang Gung Memorial Hospital, Linkou, Taiwan. tulu@ms36.hinet.net.
authors.forename: Jung-Lung
authors.initials: JL
authors.lastname: Hsu
authors.affiliation: School of Public Health, College of Public Health and Nutrition, Taipei Medical University, 250 Wu-Hsing Street, Taipei City, 110, Taiwan. elvics@gmail.com.
authors.forename: Yen-Chun
authors.initials: YC
authors.lastname: Fan
authors.affiliation: School of Public Health, College of Public Health and Nutrition, Taipei Medical University, 250 Wu-Hsing Street, Taipei City, 110, Taiwan. ylhuang@tmu.edu.tw.|Department of Public Health, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei City, 110, Taiwan. ylhuang@tmu.edu.tw.
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Huang
authors.affiliation: Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan. romanray92@gmail.com.
authors.forename: Jui
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan. m000735@ms.skh.org.tw.
authors.forename: Wei-Hung
authors.initials: WH
authors.lastname: Chen
authors.affiliation: Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan. m001012@ms.skh.org.tw.
authors.forename: Hou-Chang
authors.initials: HC
authors.lastname: Chiu
authors.affiliation: School of Public Health, College of Public Health and Nutrition, Taipei Medical University, 250 Wu-Hsing Street, Taipei City, 110, Taiwan. baich@tmu.edu.tw.|Department of Public Health, College of Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei City, 110, Taiwan. baich@tmu.edu.tw.
authors.forename: Chyi-Huey
authors.initials: CH
authors.lastname: Bai
mesh_terms: D000368:Aged; D019540:Area Under Curve; D003704:Dementia / Q000175:diagnosis*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004522:Educational Status; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012372:ROC Curve; D012680:Sensitivity and Specificity