title: Formal [3 + 2]-Cycloaddition of Donor-Acceptor Cyclopropanes to 1,3-Dienes: Cyclopentane Assembly.
abstract: We report a new simple method to access highly substituted cyclopentanes via Lewis acid-initiated formal [3 + 2]-cycloaddition of donor-acceptor cyclopropanes to 1,3-dienes. This process displays exceptional chemo- and regioselectivity as well as high diastereoselectivity, allowing for the synthesis of functionalized cyclopentanes and bicyclic cyclopentane-based structures in moderate to high yields. Moreover, one-pot synthesis of biologically relevant cyclopentafuranones, based on reaction of donor-acceptor cyclopropanes with dienes, has been developed.
authors.affiliation: Department of Chemistry, M.V. Lomonosov Moscow State University , Leninskie Gory 1-3, Moscow 119991, Russia.|Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitrii Rogachev , Samory Mashela 1, Moscow 117997, Russia.
authors.forename: Ekaterina M
authors.initials: EM
authors.lastname: Budynina
authors.affiliation: Department of Chemistry, M.V. Lomonosov Moscow State University , Leninskie Gory 1-3, Moscow 119991, Russia.|Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitrii Rogachev , Samory Mashela 1, Moscow 117997, Russia.
authors.forename: Olga A
authors.initials: OA
authors.lastname: Ivanova
authors.affiliation: Department of Chemistry, M.V. Lomonosov Moscow State University , Leninskie Gory 1-3, Moscow 119991, Russia.|Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitrii Rogachev , Samory Mashela 1, Moscow 117997, Russia.
authors.forename: Alexey O
authors.initials: AO
authors.lastname: Chagarovskiy
authors.affiliation: Department of Chemistry, M.V. Lomonosov Moscow State University , Leninskie Gory 1-3, Moscow 119991, Russia.
authors.forename: Yuri K
authors.initials: YK
authors.lastname: Grishin
authors.affiliation: Department of Chemistry, M.V. Lomonosov Moscow State University , Leninskie Gory 1-3, Moscow 119991, Russia.|Federal Research Center of Pediatric Hematology, Oncology and Immunology named after Dmitrii Rogachev , Samory Mashela 1, Moscow 117997, Russia.
authors.forename: Igor V
authors.initials: IV
authors.lastname: Trushkov
authors.affiliation: Department of Chemistry, M.V. Lomonosov Moscow State University , Leninskie Gory 1-3, Moscow 119991, Russia.
authors.forename: Mikhail Ya
authors.initials: MY
authors.lastname: Melnikov