title: Depression, anxiety and stress among patients with dialysis and the association with quality of life.
abstract: Studies addressing the nature of relationship between psychological symptoms and quality of life among dialysis patients in Malaysia are scarce. Hence, this study is intended to investigate the association between psychological symptoms such as depression, anxiety and stress on the quality of life in dialysis patients. A cross sectional multicentre study was conducted from May to October 2012 at 15 centres that provide haemodialysis and/or peritoneal dialysis. Apart from socio-demographic profile data collection, WHOQOL-BREF and DASS21 questionnaires were administered to study subjects. All three psychological symptoms had significant impact on quality of life domains of physical health, psychological health, social impact, perceived environment and overall quality of life. These findings suggest that subjects with symptoms of depression, anxiety and stress had poorer quality of life than those without, highlighting the negative impact of psychological symptoms.
authors.affiliation: Biostatistics Unit, Clinical Research Centre, 1st Floor, MMA Building, 124 Jalan Pahang, 53000 Kuala Lumpur, Malaysia. Electronic address: adam@crc.gov.my.
authors.forename: Mohamad A
authors.initials: MA
authors.lastname: Bujang
authors.affiliation: Department of Psychiatry, International Islamic University, Kuantan, Malaysia.
authors.forename: Ramli
authors.initials: R
authors.lastname: Musa
authors.affiliation: Department of Medicine, Sultanah Aminah Hospital, Johor Bahru, Malaysia.
authors.forename: Wen J
authors.initials: WJ
authors.lastname: Liu
authors.affiliation: Seremban KPJ Specialist Hospital, Seremban, Malaysia.
authors.forename: Thian F
authors.initials: TF
authors.lastname: Chew
authors.affiliation: Universiti Putra Malaysia, Serdang, Malaysia.
authors.forename: Christopher T S
authors.initials: CT
authors.lastname: Lim
authors.affiliation: Ampang Puteri Hospital, Kuala Lumpur, Malaysia.
authors.forename: Zaki
authors.initials: Z
authors.lastname: Morad
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D006435:Renal Dialysis / Q000009:adverse effects / Q000523:psychology; D013315:Stress, Psychological / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D011795:Surveys and Questionnaires
keywords: Anxiety; Depression; Dialysis patients; Quality of life; Stress