title: Polymer-Decorated Carbon Nanotubes as Transducers for Label-Free Photonic Biosensors.
abstract: A biosensor taking advantage of the optical properties of sorted carbon nanotubes has been developed. A polyfluorene polymer bearing azido groups was synthesized and used for the selective extraction of semi-conducting nanotubes from the bulk population. The resulting polymer-decorated nanotubes were then conjugated by click-chemistry to a ligand unit (biotin), and the sensing properties of the biotinylated nanotubes were investigated by photoluminescence measurements, upon interaction with the streptavidin target.
authors.affiliation: CEA, IBITECS, Service de Chimie Bioorganique et de Marquage, 91191 Gif-sur-Yvette (France).
authors.forename: Elise
authors.initials: E
authors.lastname: Villemin
authors.affiliation: CEA, IBITECS, Service de Chimie Bioorganique et de Marquage, 91191 Gif-sur-Yvette (France).
authors.forename: Edmond
authors.initials: E
authors.lastname: Gravel
authors.affiliation: Institut d'Electronique Fondamentale, UMR8622, CNRS-Univ. Paris-Sud, 91405 Orsay (France).|Laboratoire Charles Coulomb, CNRS-UMR 5221, Univ. Montpellier, 34095 Montpellier (France).
authors.forename: Nicolas
authors.initials: N
authors.lastname: Izard
authors.affiliation: CEA, IRAMIS, Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie, LICSEN, 91191 Gif-sur-Yvette (France).
authors.forename: Arianna
authors.initials: A
authors.lastname: Filoramo
authors.affiliation: Institut d'Electronique Fondamentale, UMR8622, CNRS-Univ. Paris-Sud, 91405 Orsay (France). laurent.vivien@u-psud.fr.
authors.forename: Laurent
authors.initials: L
authors.lastname: Vivien
authors.affiliation: CEA, IBITECS, Service de Chimie Bioorganique et de Marquage, 91191 Gif-sur-Yvette (France). eric.doris@cea.fr.
authors.forename: Eric
authors.initials: E
authors.lastname: Doris
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D001710:Biotin / Q000737:chemistry*; D057930:Click Chemistry; D037742:Nanotubes, Carbon / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D019809:Streptavidin / Q000737:chemistry*; D014159:Transducers
chemical_list: D037742:Nanotubes, Carbon; D011108:Polymers; D001710:Biotin; D019809:Streptavidin
keywords: biosensor; carbon nanotubes; click; extracting polymer; photoluminescence