title: BNP and NT-proBNP elevation after running--a systematic review.
abstract: OBJECTIVE
  A systematic review was carried out to study the pattern of BNP and NT-proBNP release after running.
  
  
  METHODS
  Data were collected by searching the PubMed, ISI Web of Knowledge and Scopus databases.
  
  
  RESULTS
  Fifty-three reports were identified as meeting the pre-specified criteria. Twenty-seven reports, representing 1,034 participants, presented data comparing post-running BNP or NT-proBNP levels with a pre-specified cut-off. Values exceeding the upper reference limit were seen in 22.9% and 35.9% of runners, respectively.
  
  
  CONCLUSIONS
  Studies have shown post-running values exceeding the upper reference limit in up to a third of runners.
authors.forename: Eduardo M
authors.initials: EM
authors.lastname: Vilela
authors.forename: Rita
authors.initials: R
authors.lastname: Bettencourt-Silva
authors.forename: José P L
authors.initials: JP
authors.lastname: Nunes
authors.forename: Vasco G
authors.initials: VG
authors.lastname: Ribeiro
mesh_terms: D015415:Biomarkers / Q000097:blood; D015444:Exercise / Q000502:physiology*; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D012420:Running; D013997:Time Factors; D015854:Up-Regulation
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain
keywords: NT-proBNP; Running; brain natriuretic peptide