title: A Handy Field-Portable ELISA System for Rapid Onsite Diagnosis of Infectious Diseases.
abstract: Enzyme-linked immunosorbent assays (ELISAs) are considered the gold standard for the detection of various immunological reactions and can be used for the detection of infectious diseases during outbreaks or in the care of individual patients. To be useful in the timely implementation of prevention and control measures against infectious diseases, a diagnostic modality should be rapid, accurate, and affordable. In the current study, we demonstrate the efficiency (90% less time and volume consumption compared with those of a standard 96-well ELISA), detection capability, and ease of operation of a field-portable, battery-operated ELISA system, approximately the size of a cellular phone (12 × 6 × 5.5 cm), in the serological diagnosis of measles and rubella viruses that has the potential for onsite testing such as during disease outbreaks.
authors.affiliation: Department of Intelligent Mechanical Systems, Graduate School of System Design, Tokyo Metropolitan University.
authors.forename: Harpal
authors.initials: H
authors.lastname: Singh
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Morioka
authors.forename: Masayuki
authors.initials: M
authors.lastname: Shimojima
authors.forename: Le
authors.initials: L
authors.lastname: Van An
authors.forename: Hizuru
authors.initials: H
authors.lastname: Nakajima
authors.forename: Akihide
authors.initials: A
authors.lastname: Hemmi
authors.forename: Katsumi
authors.initials: K
authors.lastname: Uchiyama
authors.forename: Shih Keng
authors.initials: SK
authors.lastname: Loong
authors.forename: Sazaly
authors.initials: S
authors.lastname: AbuBakar
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
authors.forename: Masami
authors.initials: M
authors.lastname: Sugamata
mesh_terms: D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D006801:Humans; D008457:Measles / Q000175:diagnosis*; D019095:Point-of-Care Systems; D012409:Rubella / Q000175:diagnosis*; D012698:Serologic Tests / Q000379:methods*; D013997:Time Factors