title: Occupational Airborne Contact Dermatitis From Proton Pump Inhibitors.
abstract: Few published reports have described occupational contact dermatitis from proton pump inhibitor (PPI) exposure in the literature. We present an additional case of a 58-year-old male pharmaceutical worker with an occupational airborne allergic contact dermatitis to PPIs confirmed by patch testing. This is a novel report of workplace exposure to dexlansoprazole and esomeprazole PPIs with resultant clinical contact allergy and relevant positive patch test results to these 2 agents. A literature review of all previously reported cases of occupational contact dermatitis to PPI is summarized. The case also emphasizes the importance of even minute exposures when considering workplace accommodation.
authors.affiliation: From the *Division of Dermatology, University of Toronto; and †Department of Occupational and Environmental Health, St. Michael's Hospital, Toronto; and ‡University of Ottawa, Ontario, Canada.
authors.forename: Joel G
authors.initials: JG
authors.lastname: DeKoven
authors.forename: Ashley M
authors.initials: AM
authors.lastname: Yu
mesh_terms: D000395:Air Pollutants, Occupational / Q000633:toxicity*; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000209:etiology*; D005143:Eyelids; D005148:Facial Dermatoses / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck; D054328:Proton Pump Inhibitors / Q000633:toxicity*
chemical_list: D000395:Air Pollutants, Occupational; D054328:Proton Pump Inhibitors