title: The association between SDF-1 G801A polymorphism and non-small cell lung cancer risk in a Chinese Han population.
abstract: BACKGROUND
  SDF-1 G801A polymorphism is reported to correlate with cancer susceptibility. However, the association between SDF-1 G801A polymorphism and non-small cell lung cancer (NSCLC) risk in Chinese populations remains unknown.
  
  
  METHODS
  A total of 408 NSCLC patients and 303 health controls included in this study. Restriction length fragment polymorphism (RFLP) analysis was used to assess the frequencies of SDF-1 G801A polymorphic variant.
  
  
  RESULTS
  No significant association was found between SDF-1 G801A polymorphism and NSCLC risk (OR=1.268, 95% CI 0.811-2.583, P=0.361). Furthermore, SDF-1 G801A polymorphism was not correlated with histological type (P=0.697) and TNM stage (P=0.276).
  
  
  CONCLUSIONS
  SDF-1 G801A polymorphism was not a risk factor for NSCLC in Chinese Han population.
authors.affiliation: Department of Respiratory, Zhujiang Hospital, Southern Medical University Guangzhou, China ; Department of Respiratory, Mianyang Central Hospital Mianyang, China.
authors.forename: Weiguo
authors.initials: W
authors.lastname: Xu
authors.affiliation: Department of Respiratory, Mianyang Central Hospital Mianyang, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Cui
authors.affiliation: Department of Respiratory, Zhujiang Hospital, Southern Medical University Guangzhou, China.
authors.forename: Huapeng
authors.initials: H
authors.lastname: Yu
keywords: Non-small cell lung cancer; SDF-1; genetics; polymorphism