title: [Impact of air pollution on the development of asthma].
abstract: Air pollution affects the origin and evolution of respiratory diseases. The increased frequency of asthma in recent years has been associated with growth air pollutants and small particles produced from the combustion of petroleum or cigarette smoke. Some mechanisms of how these contaminants can influence asthma and other allergic diseases are known: 1) acting as irritating on alveolar epithelial cells, 2) actin as adjuvant for allergens inflammation, 3) and epigenetic mechanisms. In this review, we discuss the pathophysiological mechanisms by which air pollutants become risk factors for the development of asthma and other allergic diseases.
authors.affiliation: Grupo de Alergia Clínica y Experimental. IPS Universitaria, Universidad de Antioquia, Medellín, Antioquia, Colombia. jotamsc@yahoo.com.
authors.forename: Jorge
authors.initials: J
authors.lastname: Sánchez
authors.forename: Luis
authors.initials: L
authors.lastname: Caraballo
keywords: adjuvant allergen; air pollution; asthma; inflammation; oxidative stress