title: The Changes of Retinal Saturation after Long-Term Tamponade with Silicone Oil.
abstract: OBJECTIVE
  To evaluate the effects of long-term tamponade with silicone oil on retinal saturation.
  
  
  METHODS
  A total of 49 eyes that received tamponade with silicone oil were included. The patients were divided into 3 groups (3-6 months, 6-9 months, and >9 months) according to the duration of silicone oil tamponade. Retinal oximetry was performed using the Oxymap system before and 2 months after silicone oil removal.
  
  
  RESULTS
  The mean retinal oxygen saturation before silicone oil removal was 107% ± 12% in the arterioles and 60% ± 10% in the venules, with an overall arteriovenous difference (AVD) of 47% ± 14%. The AVD in the >9-month group was significantly higher than that in the 3-6-month group (54% ± 16% versus 44% ± 11%, P = 0.042). After silicone oil removal, the AVD in the >9-month group was significantly decreased (45% ± 9% versus 54% ± 16%, P = 0.009); additionally, the arterioles were significantly wider than before surgery (10.8 ± 0.7 pixels versus 10.4 ± 0.9 pixels, P = 0.015).
  
  
  CONCLUSIONS
  The tamponade with silicone oil for more than 9 months will cause the alterations of retinal saturation and the narrowing of retinal arterioles, which may further interfere with the oxygen metabolism in the retina.
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.
authors.forename: Bingsheng
authors.initials: B
authors.lastname: Lou
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Yuan
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.
authors.forename: Liwen
authors.initials: L
authors.lastname: He
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.
authors.forename: Lixia
authors.initials: L
authors.lastname: Lin
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.
authors.forename: Qianying
authors.initials: Q
authors.lastname: Gao
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Lin
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry; D010100:Oxygen / Q000032:analysis*; D011446:Prospective Studies; D012160:Retina / Q000187:drug effects* / Q000601:surgery; D012163:Retinal Detachment / Q000601:surgery; D012171:Retinal Vessels / Q000187:drug effects* / Q000473:pathology / Q000502:physiology; D012827:Silicone Oils / Q000009:adverse effects* / Q000627:therapeutic use*; D060205:Therapeutic Occlusion / Q000009:adverse effects / Q000379:methods; D014821:Vitrectomy
chemical_list: D012827:Silicone Oils; D010100:Oxygen