title: Phosphinic acid-promoted addition reaction of isocyanides to (Z)-hydroximoyl chlorides: efficient synthesis of α-(hydroxyimino)amides.
abstract: The reaction of (Z)-hydroximoyl chlorides with isocyanides promoted by phosphinic acid in the presence of triethylamine proceeds smoothly to afford α-(hydroxyimino)amides in good to high yields. Phosphinic acid plays an important role in effectively promoting the reaction. A wide range of (Z)-hydroximoyl chlorides and isocyanides were found to be suitable for this reaction.
authors.affiliation: Division of Material Chemistry, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa 920-1192, Japan. soeta@se.kanazawa-u.ac.jp ukaji@staff.kanazawa-u.ac.jp.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Soeta
authors.forename: Suguru
authors.initials: S
authors.lastname: Takashita
authors.forename: Yoko
authors.initials: Y
authors.lastname: Sakata
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Ukaji