title: Flexible fibers wet-spun from formic acid modified chitosan.
abstract: The rigidity and low strain of chitosan fibers hindered their broader utility for biomedical applications. In present work, formic acid was employed as an efficient modifier for chitosan to prepare flexible fibers wet-spun from the formic acid modified chitosan solution. The formation of amide linkages between chitosan and formic acid was confirmed by FTIR, (13)C NMR, (1)H NMR and XRD measurements. The degree of formylation evaluated by (1)H NMR spectra was varied from 14.1% to 37.2% as a function of the reaction temperature. The results of the mechanical properties showed that the as-spun fibers exhibited an enhanced ductility with a maximum elongation at break of 21.7% compared with that spun from the chitosan dissolved in diluted acetic acid. The novel flexible chitosan fibers were anticipated to be used as comfortable wound dressing and bandages in biomedical fields.
authors.affiliation: Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing 210044, China.
authors.forename: Jinlei
authors.initials: J
authors.lastname: Li
authors.affiliation: Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing 210044, China. Electronic address: dagang@nuist.edu.cn.
authors.forename: Dagang
authors.initials: D
authors.lastname: Liu
authors.affiliation: Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing 210044, China.
authors.forename: Chengming
authors.initials: C
authors.lastname: Hu
authors.affiliation: Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing 210044, China.
authors.forename: Fengxiang
authors.initials: F
authors.lastname: Sun
authors.affiliation: Collaborative Innovation Center of Atmospheric Environment and Equipment Technology, Nanjing University of Information Science & Technology, Nanjing 210044, China.
authors.forename: Williamson
authors.initials: W
authors.lastname: Gustave
authors.affiliation: Department of Materials Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.
authors.forename: Huafeng
authors.initials: H
authors.lastname: Tian
authors.affiliation: State Key Laboratory For Modification of Chemical Fibers and Polymer Materials, College of Material Science and Engineering, Donghua University, Shanghai 201620, China.
authors.forename: Shuguang
authors.initials: S
authors.lastname: Yang
mesh_terms: D000577:Amides / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry*; D048271:Chitosan / Q000737:chemistry*; D005561:Formates / Q000737:chemistry*; D055595:Mechanical Phenomena
chemical_list: D000577:Amides; D001672:Biocompatible Materials; D005561:Formates; C030544:formic acid; D048271:Chitosan
keywords: Chitosan; Fibers; Formic acid; Modification