title: Serum inoculation as a possibility for elimination of porcine reproductive and respiratory syndrome (PRRS) from a farrow-to-finish pig farm.
abstract: The large heterogeneity among porcine reproductive and respiratory syndrome virus (PRRSV) isolates is probably the main obstacle to its effective control using current commercial vaccines. Intentionally exposing all breeding pigs to PRRSV circulating on the farm could eliminate porcine reproductive and respiratory syndrome (PRRS) from the herd. The objective of this study was to eliminate PRRS from a farrow-to-finish pig farm by serum inoculation. The owner was acquainted with the strict biosecurity measures. Breeding pigs were immunised with serum, which was obtained from PRRSV-positive weaners from the same farm. The percent of antibody high positive breeding pigs decreased six months after serum inoculation, while 34 months after serum inoculation no more antibody high positive pigs were detected and 56.8% of breeding pigs and all other categories were free of antibodies. In the breeding herd no virus was detected during all testing while PRRSV circulated in 2-month-old weaners until 12 months after serum inoculation. Later all tested samples from weaners, growers and fatteners were negative. Herd closure and the adoption of strict biosecurity measures are essential. Serum inoculation of the breeding herd proved to be a successful measure for eliminating PRRS from this farrow-to-finish farm.
authors.affiliation: Institute for the Health Care of Pigs, University of Ljubljana , Gerbičeva 60, 1000 Ljubljana , Slovenia.
authors.forename: Marina
authors.initials: M
authors.lastname: Štukelj
authors.affiliation: Institute for the Health Care of Pigs, University of Ljubljana , Gerbičeva 60, 1000 Ljubljana , Slovenia.
authors.forename: Jan
authors.initials: J
authors.lastname: Plut
authors.affiliation: Institute for Microbiology and Parasitology, Veterinary Faculty, University of Ljubljana , Gerbičeva 60, 1000 Ljubljana , Slovenia.
authors.forename: Ivan
authors.initials: I
authors.lastname: Toplak
keywords: PRRS; Porcine; elimination; immunisation; serum inoculation