title: Haploidentical Hematopoietic Stem Cell Transplantation: A Global Overview Comparing Asia, the European Union, and the United States.
abstract: One of the major projects of the Worldwide Network for Blood and Marrow Transplantation (WBMT) is to promote hematopoietic stem cell transplantation (HSCT) in emerging countries in the world. For these countries, HLA haploidentical HSCT (haplo-HSCT) from family members is an attractive approach because of its cost effectiveness. To learn the current status, including recent trends, of haplo-HSCT, the WBMT invited speakers from major transplant centers in 3 regions (Asia, Europe, and North America) to present at its annual WBMT Joint Session. This article represents the direct reports from these 3 speakers in addition to introductions by 2 WBMT speakers who address data from the Global Transplant Activity survey. It must be emphasized, however, that certain promising results of haplo-HSCT presented in this article were obtained at well-experienced institutes.
authors.affiliation: Haematology Department, Imperial College, Hammersmith Hospital, London, United Kingdom.
authors.forename: Jane
authors.initials: J
authors.lastname: Apperley
authors.affiliation: Division of Hematology and Medical Oncology, University of Leipzig, Leipzig, Germany.
authors.forename: Dietger
authors.initials: D
authors.lastname: Niederwieser
authors.affiliation: Peking University Institute of Hematology, Peking University People's Hospital, Beijing Key Laboratory of HSCT, Beijing, Peoples Republic of China.
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Huang
authors.affiliation: Hematology Division BMT and Cord Blood Bank, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
authors.forename: Arnon
authors.initials: A
authors.lastname: Nagler
authors.affiliation: Sidney Kimmel Comprehensive Cancer Center, Blood and Bone Marrow Cancers Program, The Johns Hopkins University, Baltimore, Maryland.
authors.forename: Ephraim
authors.initials: E
authors.lastname: Fuchs
authors.affiliation: Department of Clinical Haematology & BMT Service, The Royal Melbourne Hospital, Melbourne, Australia.
authors.forename: Jeff
authors.initials: J
authors.lastname: Szer
authors.affiliation: Department of Promotion for Blood and Marrow Transplantation, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan. Electronic address: ykodera@river.ocn.ne.jp.
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Kodera
mesh_terms: D064591:Allografts; D001208:Asia; D005062:European Union; D018380:Hematopoietic Stem Cell Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D014481:United States
keywords: Beijing Protocol; Europe; Global Activity Survey; Haplo-HSCT; Haplo-transplantation; United States