title: A comparison of the femur heads histomorphometrically regarding trabecular bone properties in the patients with osteoporosis and osteoarthritis.
abstract: The purpose was to compare the bone samples histomorphometrically regarding trabecular bone properties in the patients with osteoarthritis (OA) and osteoporosis (OP). Femoral head specimens were obtained from 18 patients with OA and 17 patients with femoral neck fracture due to OP during hip arthroplasty. Histomorphometric analyses were performed by soft ware program (Carl Zeiss) to measure trabecular area (Tb.a, mm(3)), trabecular thickness (Tb.th, µm) and trabecular separation (Tb.s, µm). In the results, Tb.a and Tb.th values were significantly lower (p < 0.05), Tb.s was higher in the patients with OP (p < 0.05). Bone metabolism parameters were different between the groups (p < 0.05). All histomorphometric parameters were highly correlated with the BMDs (p < 0.01). This study showed inverse relation between OA and OP regarding trabecular bone properties, BMD and bone turnover metabolism markers. The strong relations between results suggest that either BMDs or bone turnover markers can be used for prescience of the fractures.
authors.affiliation: Fiziksel Tıp ve Rehabilitasyon Anabilim Dali, Ege Universitesi Tip Fakultesi, Bornova, Izmir, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Cınar
authors.affiliation: Fiziksel Tıp ve Rehabilitasyon Anabilim Dali, Ege Universitesi Tip Fakultesi, Bornova, Izmir, Turkey. atamaz_02@yahoo.com.
authors.forename: F C
authors.initials: FC
authors.lastname: Atamaz
authors.affiliation: Fiziksel Tıp ve Rehabilitasyon Anabilim Dali, Ege Universitesi Tip Fakultesi, Bornova, Izmir, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Kirazli
authors.affiliation: Department of Pathology, Ege University Medical Faculty, Bornova, Izmir, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Doganavsargil
authors.affiliation: Department of Pathology, Ege University Medical Faculty, Bornova, Izmir, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Sezak
authors.affiliation: Department of Orthopaedic Surgery, Ege University Medical Faculty, Bornova, Izmir, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Ozkayin
authors.affiliation: Department of Orthopaedic Surgery, Ege University Medical Faculty, Bornova, Izmir, Turkey.
authors.forename: K
authors.initials: K
authors.lastname: Aktuglu
authors.affiliation: Department of Orthopaedic Surgery, Ege University Medical Faculty, Bornova, Izmir, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Aydogdu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000071556:Cancellous Bone / Q000473:pathology*; D005260:Female; D005270:Femur Head / Q000473:pathology*; D050723:Fractures, Bone / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000473:pathology*; D010024:Osteoporosis / Q000473:pathology*
keywords: Bone Turnover Marker; Bone densitometry; Osteoarthritis; Osteoporosis