title: Bedside heart type fatty acid binding protein (H-FABP): Is an early predictive marker of cardiac syncope.
abstract: OBJECTIVE
  To determine the value of bedside heart-type fatty acid binding protein in diagnosis of cardiac syncope in patients presenting with syncope or presyncope.
  
  
  METHODS
  The prospective study was conducted at Ankara Numune Training and Research Hospital, Ankara, Turkey, between September 1, 2010, and January 1, 2011, and comprised patients aged over 18 years who presented with syncope or presyncope. Patients presenting to emergency department within 4 hours of syncope or presyncope underwent a bedside heart-type fatty acid binding protein test measurement. SPSS 16 was used for statistical analysis.
  
  
  RESULTS
  Of the 100 patients evaluated, 22(22%) were diagnosed with cardiac syncope. Of them, 13(59.1%) patients had a positive and 9(40.9%) had a negative heart-type fatty acid binding protein result. Consequently, the test result was 12.64 times more positive in patients with cardiac syncope compared to those without.
  
  
  CONCLUSIONS
  Bedside heart-type fatty acid binding protein, particularly at early phase of myocardial injury, reduces diagnostic and therapeutic uncertainity of cardiac origin in syncope patients.
authors.affiliation: Department of Emergency Medicine, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Bedriye Muge
authors.initials: BM
authors.lastname: Sonmez
authors.affiliation: Emergency Medicine Department, Sisli Etfal Education and Research Hospital, Istanbul, Turkey.
authors.forename: Derya
authors.initials: D
authors.lastname: Ozturk
authors.affiliation: Department of Emergency Medicine, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Fevzi
authors.initials: F
authors.lastname: Yilmaz
authors.affiliation: Emergency Medicine Department, Sisli Etfal Education and Research Hospital, Istanbul, Turkey.
authors.forename: Ertugrul
authors.initials: E
authors.lastname: Altinbilek
authors.affiliation: Department of Emergency, Faculty of Medicine, Baskent Univercity, Ankara, Turkey.
authors.forename: Cemil
authors.initials: C
authors.lastname: Kavalci
authors.affiliation: Department of Emergency Medicine, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Tamer
authors.initials: T
authors.lastname: Durdu
authors.affiliation: Department of Emergency Medicine, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Oktay
authors.initials: O
authors.lastname: Hakbilir
authors.affiliation: Department of Biochemistry, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Turan
authors.initials: T
authors.lastname: Turhan
authors.affiliation: Department of Emergency Medicine, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Ongar
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D004636:Emergency Service, Hospital; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins / Q000097:blood*; D005260:Female; D006331:Heart Diseases / Q000097:blood* / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000067716:Point-of-Care Testing; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013575:Syncope / Q000097:blood* / Q000209:etiology*; D014421:Turkey; D055815:Young Adult
chemical_list: D015415:Biomarkers; C493408:FABP3 protein, human; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins
keywords: Syncope, H-FABP, Emergency department.