title: Triterpenoids from the Herbs of Salicornia bigelovii.
abstract: A new nortriterpene saponin, 3-O-β-d-glucuronopyranosyl-30-norolean-12,20(29)-dien-23- oxo-28-oic acid, namely bigelovii D (11), was isolated from the hydroalcoholic extract of herbs of Salicornia bigelovii along with 10 known saponins (1-10). Their chemical structures were identified on the basis of spectroscopic analyses including two-dimensional NMR and a comparison with literature data. Some of these compounds showed potent antifungal activities in vitro. Compounds 3, 4, 5, 6, 7, 10 and 11 demonstrated potent inhibitory activities against Colletotrichum gloeosporioides and compound 11 displayed broad-spectrum inhibitory activity against Alternaria alternata, A. solani, Botrytis cinerea, C. gloeosporioides, Fusarium graminearum, F. verticilloides, Thanatephorus cucumeris and Sclerotinia sclerotiorum, with EC50 values ranging from 13.6 to 36.3 μg/mL.
authors.affiliation: Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. attilayu@hotmail.com.|Jiangsu Provincial Platform for Conservation and Utilization of Agricultural Germplasm, Nanjing 210014, China. attilayu@hotmail.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Shan
authors.affiliation: Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. lihuan405@sina.cn.
authors.forename: Huan
authors.initials: H
authors.lastname: Li
authors.affiliation: Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. tube1031aaa@126.com.
authors.forename: Fuqin
authors.initials: F
authors.lastname: Guan
authors.affiliation: Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. chenyu.1007@163.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. epmin@sohu.com.
authors.forename: Min
authors.initials: M
authors.lastname: Yin
authors.affiliation: Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. wangmingwm0208@sina.com.
authors.forename: Ming
authors.initials: M
authors.lastname: Wang
authors.affiliation: Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. fengxucnbg@cnbg.net.
authors.forename: Xu
authors.initials: X
authors.lastname: Feng
authors.affiliation: Jiangsu Key Laboratory for Bioresources of Saline Soils, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China. wangqizhi@cnbg.net.
authors.forename: Qizhi
authors.initials: Q
authors.lastname: Wang
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology; D019663:Chenopodiaceae / Q000737:chemistry*; D020231:Colletotrichum / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts; D014315:Triterpenes
keywords: Salicornia bigelovii Torr.; antifungal activity; nortriterpenoid saponins