title: Relationship between etonogestrel level and BMI in women using the contraceptive implant for more than 1 year.
abstract: Progestin-only contraceptive methods, including the 3-year, single-rod etonogestrel (ENG) implant, may be preferred for obese women to avoid additional estrogen-related thrombosis risk; however, whether obese women receive an ENG sufficient dose to suppress ovulation is understudied. Our analysis expands on the limited information currently available by studying ENG levels related to body mass index (BMI) in a community sample of primarily Hispanic women. This cross-sectional, descriptive study of 52 long-term implant users found comparable ENG levels across a wide BMI range (p=.1). These results further support that ENG levels are independent of BMI through 3 years of implant use and are thus reassuring that ENG implants will be effective for women of all BMIs.
authors.affiliation: Department of Obstetrics and Gynecology, Columbia University Medical Center, 622 W 168th Street, PH 16-69, New York, NY, 10032, USA. Electronic address: kmm2112@columbia.edu.
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Morrell
authors.affiliation: Biomarkers Core Laboratory, Irving Institute for Clinical and Translational Research, Columbia University Medical Center, 630 W 168th Street, PH 10-105b, New York, NY, 10027, USA. Electronic address: sc2752@columbia.edu.
authors.forename: Serge
authors.initials: S
authors.lastname: Cremers
authors.affiliation: Department of Obstetrics and Gynecology and Epidemiology, Columbia University Medical Center, 622 W 168th Street, PH 16-69, New York, NY, USA. Electronic address: clw3@columbia.edu.
authors.forename: Carolyn L
authors.initials: CL
authors.lastname: Westhoff
authors.affiliation: Department of Obstetrics and Gynecology, Columbia University Medical Center, 622 W 168th Street, PH 16-69, New York, NY, 10032, USA. Electronic address: ard4@columbia.edu.
authors.forename: Anne R
authors.initials: AR
authors.lastname: Davis
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D017135:Desogestrel / Q000008:administration & dosage* / Q000097:blood*; D004343:Drug Implants; D005260:Female; D006801:Humans; D009765:Obesity / Q000097:blood; D034445:Ovulation Inhibition; D055815:Young Adult
chemical_list: D004343:Drug Implants; C044815:etonogestrel; D017135:Desogestrel
keywords: Contraception; Etonogestrel; Implant; Obesity