title: The Role of Maternal Dietary Proteins in Development of Metabolic Syndrome in Offspring.
abstract: The prevalence of metabolic syndrome and obesity has been increasing. Pre-natal environment has been suggested as a factor influencing the risk of metabolic syndrome in adulthood. Both observational and experimental studies showed that maternal diet is a major modifier of the development of regulatory systems in the offspring in utero and post-natally. Both protein content and source in maternal diet influence pre- and early post-natal development. High and low protein dams' diets have detrimental effect on body weight, blood pressure191 and metabolic and intake regulatory systems in the offspring. Moreover, the role of the source of protein in a nutritionally adequate maternal diet in programming of food intake regulatory system, body weight, glucose metabolism and blood pressure in offspring is studied. However, underlying mechanisms are still elusive. The purpose of this review is to examine the current literature related to the role of proteins in maternal diets in development of characteristics of the metabolic syndrome in offspring.
authors.affiliation: Department of Nutrition and Dietetics, Brook College of Health, University of North Florida, UNF Dr. Bldg 39, Room 3057A, Jacksonville, FL 32224, USA. alireza.jahan-mihan@unf.edu.
authors.forename: Alireza
authors.initials: A
authors.lastname: Jahan-Mihan
authors.affiliation: Department of Nutrition and Dietetics, Brook College of Health, University of North Florida, UNF Dr. Bldg 39, Room 3057A, Jacksonville, FL 32224, USA. jrodrigu@unf.edu.
authors.forename: Judith
authors.initials: J
authors.lastname: Rodriguez
authors.affiliation: Department of Nutrition and Dietetics, Brook College of Health, University of North Florida, UNF Dr. Bldg 39, Room 3057A, Jacksonville, FL 32224, USA. c.christie@unf.edu.
authors.forename: Catherine
authors.initials: C
authors.lastname: Christie
authors.affiliation: Department of Nutrition and Dietetics, Brook College of Health, University of North Florida, UNF Dr. Bldg 39, Room 3057A, Jacksonville, FL 32224, USA. n00961956@ospreys.unf.edu.
authors.forename: Marjan
authors.initials: M
authors.lastname: Sadeghi
authors.affiliation: Department of Nutrition and Dietetics, Brook College of Health, University of North Florida, UNF Dr. Bldg 39, Room 3057A, Jacksonville, FL 32224, USA. tjz1973@comcast.net.
authors.forename: Tara
authors.initials: T
authors.lastname: Zerbe
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D001823:Body Composition; D001835:Body Weight; D002784:Cholesterol / Q000378:metabolism; D059305:Diet, High-Fat; D018753:Diet, Protein-Restricted; D004044:Dietary Proteins / Q000008:administration & dosage*; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D008099:Liver / Q000378:metabolism; D039382:Maternal Nutritional Physiological Phenomena; D024821:Metabolic Syndrome / Q000517:prevention & control*; D009765:Obesity / Q000517:prevention & control*; D064887:Observational Studies as Topic; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012307:Risk Factors; D014280:Triglycerides / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D004044:Dietary Proteins; D014280:Triglycerides; D002784:Cholesterol
keywords: fetal programming; metabolic syndrome; protein