title: LONG-TERM RESULTS OF COMBINED AB INTERNO TRABECULOTOMY (TRABECTOME) AND SMALL-GAUGE PARS PLANA VITRECTOMY.
abstract: OBJECTIVE
  To report outcomes of patients who have undergone combined Trabectome and pars plana vitrectomy.
  
  
  METHODS
  Institutional Review Board-approved retrospective chart review of patients seen at the Cincinnati Eye Institute before January 2014 undergoing combined Trabectome and pars plana vitrectomy for uncontrolled glaucoma and visually significant retina pathology. Charts were reviewed to identify changes in intraocular pressure, visual acuity, and change in glaucoma medication requirement up to 1 year after surgery.
  
  
  RESULTS
  Four patients met the inclusion criteria with 12-month follow-up, and two of the patients were male. All patients underwent 25-gauge pars plana vitrectomy and Trabectome surgery. Mean preoperative LogMAR visual acuity was 0.39 (20/49) and 12-month LogMAR visual acuity was 0.21 (20/32) (P = 0.06). Mean preoperative intraocular pressure was 17 mmHg and mean preoperative glaucoma medication requirement was 2.5 topical medications. Twelve-month mean intraocular pressure was 12.8 mmHg (P = 0.07), and mean topical glaucoma medication requirement was 2.3 medications (P = 0.39). All patients were off steroids and anti-inflammatories at the final visit. One patient developed a hyphema requiring anterior chamber washout at 1 week. No other complications occurred.
  
  
  CONCLUSIONS
  The results suggest that combined Trabectome and pars plana vitrectomy seems effective in the management of glaucoma in patients with visually significant retina pathology.
authors.affiliation: Department of Ophthalmology, University of Cincinnati, Cincinnati Eye Institute, Cincinnati, Ohio.
authors.forename: Brian
authors.initials: B
authors.lastname: Toussaint
authors.forename: Michael R
authors.initials: MR
authors.lastname: Petersen
authors.forename: Robert A
authors.initials: RA
authors.lastname: Sisk
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Riemann
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Miller
authors.forename: Robert E
authors.initials: RE
authors.lastname: Foster
authors.forename: Adeel H
authors.initials: AH
authors.lastname: Shaikh
authors.forename: Anup H
authors.initials: AH
authors.lastname: Khatana
authors.forename: Jeff
authors.initials: J
authors.lastname: Zink
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Greff
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D019654:Lens Implantation, Intraocular; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D018918:Phacoemulsification; D011379:Prognosis; D012164:Retinal Diseases / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D014129:Trabecular Meshwork / Q000601:surgery; D014130:Trabeculectomy / Q000379:methods*; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000379:methods*