title: [Immune response and oxidative stress in hepatitis C virus infection].
abstract: This review summarizes our current knowledge of the innate and adaptive immune responses induced by hepatitis C virus, and of the genetic polymorphisms that may determine the outcome of the disease. In addition, the authors discuss the role of reactive oxygen species and oxidative stress in hepatitis C virus-related pathogenic processess, such as hepatitis, fibrosis, hepatocellular carcinoma, steatosis and insulin resistance.
authors.affiliation: I. Belgyógyászati Klinika, Pécsi Tudományegyetem, Általános Orvostudományi Kar, Klinikai Központ Pécs, Ifjúság útja 13., 7624.
authors.forename: Alajos
authors.initials: A
authors.lastname: Pár
authors.affiliation: I. Belgyógyászati Klinika, Pécsi Tudományegyetem, Általános Orvostudományi Kar, Klinikai Központ Pécs, Ifjúság útja 13., 7624.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Pár
mesh_terms: D056704:Adaptive Immunity; D006528:Carcinoma, Hepatocellular / Q000276:immunology* / Q000378:metabolism; D005234:Fatty Liver / Q000276:immunology / Q000378:metabolism*; D016174:Hepacivirus / Q000276:immunology / Q000472:pathogenicity; D006526:Hepatitis C / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D007113:Immunity, Innate; D007333:Insulin Resistance; D008113:Liver Neoplasms / Q000276:immunology* / Q000378:metabolism; D018384:Oxidative Stress / Q000276:immunology; D020641:Polymorphism, Single Nucleotide; D017382:Reactive Oxygen Species / Q000276:immunology / Q000378:metabolism*
chemical_list: D017382:Reactive Oxygen Species
keywords: genetic polymorphisms; genetikai polimorfizmusok; hepatitis C virus; hepatitis C-vírus; immune response; immunválasz; oxidative stress; oxidatív stressz