title: [Anticonvulsant Hypersensitivity Syndrome: A Case Report].
abstract: DRESS syndrome (skin reaction with eosinophilia and systemic symptoms) is an idiosyncratic drug reaction characterized by rash, fever, lymphadenopathy, and internal organ dysfunction. This case report is on a patient with bipolar affective disorder who presented with a systemic inflammatory response associated with the use of valproic acid, and an important activation of symptoms when used with other drugs with a different pharmacological action mechanism. The diagnosis of DRESS syndrome is primarily by exclusion, and its detection may be difficult, which could potentially become fatal for the patient.
authors.affiliation: Médico psiquiatra, Profesor vinculado en pregrado y posgrado, Universidad CES, Medellín, Colombia.
authors.forename: Felipe
authors.initials: F
authors.lastname: Valderrama Escudero
authors.affiliation: Residente de tercer año de Psiquiatría, Universidad CES, Medellín, Colombia. Electronic address: lauraelisamontoya@gmail.com.
authors.forename: Laura Elisa
authors.initials: LE
authors.lastname: Montoya González
keywords: Bipolar disorder; Disfunción hepática; Hepatic dysfunction; Trastorno afectivo bipolar; Valproic acid; Ácido valproico