title: C-reactive protein, physical activity and cardiorespiratory fitness in Portuguese adolescents: a cross-sectional study.
abstract: The goal of this study was to investigate the association of physical activity (PA) and cardiorespiratory fitness with C-reactive protein (CRP) concentration in adolescents. The sample included 386 Portuguese adolescents (n = 207, female), age 12-18 years, assessed in the year 2012. The PA was assessed with the use of accelerometers, and the cardiorespiratory fitness was assessed by the Fitnessgram Pacer test. Blood samples were collected after a 10-hour fasting, and high-sensitivity PCR concentration was further assessed. Significant associations between CRP and cardiorespiratory fitness were found for females (r = -0.313; p < 0.001) and males (r = -0.163; p < 0.05); however, when adjusted by the BMI, the associations remained significant only for females (r = -0.215; p < 0.001). Regarding the association between CRP and PA, no significant associations were found for both genders. Therefore, CRP is apparently negatively associated with cardiorespiratory fitness, with differences between males and females; for females it seems less dependent than BMI.
authors.affiliation: Universidade do Porto, Porto, Portugal.
authors.forename: Cesar Aparecido
authors.initials: CA
authors.lastname: Agostinis Sobrinho
authors.affiliation: Universidade do Porto, Porto, Portugal.
authors.forename: Carla Marisa Maia
authors.initials: CM
authors.lastname: Moreira
authors.affiliation: Universidade do Porto, Porto, Portugal.
authors.forename: Jorge Augusto Pinto da Silva
authors.initials: JA
authors.lastname: Mota
authors.affiliation: Instituto Universitário da Maia, Porto, Portugal.
authors.forename: Rute Marina Roberto
authors.initials: RM
authors.lastname: Santos
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism*; D002319:Cardiovascular System / Q000378:metabolism*; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D009043:Motor Activity; D010809:Physical Fitness; D011174:Portugal; D012737:Sex Factors
chemical_list: D002097:C-Reactive Protein