title: Primary conjunctival follicular lymphoma mimicking chronic conjunctivitis.
abstract: METHODS
  The case is presented of a 43 year-old male patient with chronic follicular conjunctivitis, negative bacterial serology, and refractory to local treatment. The incisional biopsy performed showed to be consistent with reactive lymphoid hyperplasia. A year later, a new incisional biopsy showed follicular lymphoma, with no systemic involvement, and he was treated with local radiotherapy.
  
  
  CONCLUSIONS
  When a chronic follicular conjunctivitis is refractory to treatment, it is essential to perform an incisional biopsy to establish the histopathological diagnosis that can range from chronic inflammation, reactive lymphoid hyperplasia to lymphoma. Follicular lymphoma is rare among conjunctival lymphomas, and the staging is indispensable for the correct therapeutic approach.
authors.affiliation: Servicio de Oftalmología, Hospital Clínico Universitario, Valladolid, España. Electronic address: sonia_labrador@hotmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Labrador Velandia
authors.affiliation: Servicio de Anatomía Patológica, Hospital Clínico Universitario, Valladolid, España.
authors.forename: E
authors.initials: E
authors.lastname: García Lagarto
authors.affiliation: Unidad de Tumores Intraoculares, Hospital Clínico Universitario, Valladolid, España.
authors.forename: M A
authors.initials: MA
authors.lastname: Saornil
authors.affiliation: Unidad de Tumores Intraoculares, Hospital Clínico Universitario, Valladolid, España.
authors.forename: C
authors.initials: C
authors.lastname: García Álvarez
authors.affiliation: Servicio de Hematología, Hospital Clínico Universitario, Valladolid, España.
authors.forename: R
authors.initials: R
authors.lastname: Cuello
authors.affiliation: Servicio de Oncología Radioterápica, Hospital Clínico Universitario, Valladolid, España.
authors.forename: P
authors.initials: P
authors.lastname: Diezhandino
mesh_terms: D000328:Adult; D003228:Conjunctiva; D003230:Conjunctival Neoplasms / Q000175:diagnosis*; D003231:Conjunctivitis / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D008224:Lymphoma, Follicular / Q000175:diagnosis*; D008297:Male
keywords: Chronic conjunctivitis; Conjunctival lymphoma; Conjuntivitis crónica; Conjuntivitis folicular; Follicular conjunctivitis; Follicular lymphoma; Hiperplasia reactiva linfoide; Linfoma de la conjuntiva; Linfoma folicular; Reactive lymphoid hyperplasia