title: Patient-specific geometrical modeling of orthopedic structures with high efficiency and accuracy for finite element modeling and 3D printing.
abstract: We improved the geometrical modeling procedure for fast and accurate reconstruction of orthopedic structures. This procedure consists of medical image segmentation, three-dimensional geometrical reconstruction, and assignment of material properties. The patient-specific orthopedic structures reconstructed by this improved procedure can be used in the virtual surgical planning, 3D printing of real orthopedic structures and finite element analysis. A conventional modeling consists of: image segmentation, geometrical reconstruction, mesh generation, and assignment of material properties. The present study modified the conventional method to enhance software operating procedures. Patient's CT images of different bones were acquired and subsequently reconstructed to give models. The reconstruction procedures were three-dimensional image segmentation, modification of the edge length and quantity of meshes, and the assignment of material properties according to the intensity of gravy value. We compared the performance of our procedures to the conventional procedures modeling in terms of software operating time, success rate and mesh quality. Our proposed framework has the following improvements in the geometrical modeling: (1) processing time: (femur: 87.16 ± 5.90 %; pelvis: 80.16 ± 7.67 %; thoracic vertebra: 17.81 ± 4.36 %; P < 0.05); (2) least volume reduction (femur: 0.26 ± 0.06 %; pelvis: 0.70 ± 0.47, thoracic vertebra: 3.70 ± 1.75 %; P < 0.01) and (3) mesh quality in terms of aspect ratio (femur: 8.00 ± 7.38 %; pelvis: 17.70 ± 9.82 %; thoracic vertebra: 13.93 ± 9.79 %; P < 0.05) and maximum angle (femur: 4.90 ± 5.28 %; pelvis: 17.20 ± 19.29 %; thoracic vertebra: 3.86 ± 3.82 %; P < 0.05). Our proposed patient-specific geometrical modeling requires less operating time and workload, but the orthopedic structures were generated at a higher rate of success as compared with the conventional method. It is expected to benefit the surgical planning of orthopedic structures with less operating time and high accuracy of modeling.
authors.affiliation: Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopedics · Guangdong Province), Guangzhou, 510630, China. tianjixuanying@163.com.
authors.forename: Huajun
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Orthopedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
authors.forename: Chunling
authors.initials: C
authors.lastname: Xiang
authors.affiliation: Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University (Academy of Orthopedics · Guangdong Province), Guangzhou, 510630, China.|Department of Anatomy, Guangdong Provincial Key Laboratory of Medical Biomechanics, School of Basic Medical Sciences, Southern Medical University, North-1838, Guangzhou, 510515, China.
authors.forename: Canjun
authors.initials: C
authors.lastname: Zeng
authors.affiliation: Department of Anatomy, Guangdong Provincial Key Laboratory of Medical Biomechanics, School of Basic Medical Sciences, Southern Medical University, North-1838, Guangzhou, 510515, China.
authors.forename: Hanbin
authors.initials: H
authors.lastname: Ouyang
authors.affiliation: Engineering Computational Biology, School of Computer Science and Software Engineering, The University of Western Australia, 35 Stirling Highway, Crawley, WA, 6000, Australia.
authors.forename: Kelvin Kian Loong
authors.initials: KK
authors.lastname: Wong
authors.affiliation: Department of Anatomy, Guangdong Provincial Key Laboratory of Medical Biomechanics, School of Basic Medical Sciences, Southern Medical University, North-1838, Guangzhou, 510515, China. hwh@smu.edu.cn.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001696:Biomechanical Phenomena; D005260:Female; D005269:Femur / Q000033:anatomy & histology / Q000502:physiology; D020342:Finite Element Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D019637:Orthopedic Procedures; D066330:Printing, Three-Dimensional; D013131:Spine / Q000033:anatomy & histology / Q000502:physiology; D014057:Tomography, X-Ray Computed; D055815:Young Adult
keywords: Digitalization; Image segmentation; Medical imaging; Mesh quality; Orthopedic reconstruction