title: Primary orbital neuroblastoma with intraocular extension.
abstract: Neuroblastoma is an undifferentiated malignancy of primitive neuroblasts. Neuroblastoma is among the most common solid tumors of childhood. Orbital neuroblastoma is typically a metastatic tumor. In this case report, we describe a 2-year-old child with a rapidly progressing orbital tumor. Computed tomography revealed an orbital mass lesion with extraocular and intraocular components. An incisional biopsy was done, and a histopathological examination showed features suggestive of neuroblastoma. Systemic workup including ultrasonography of the abdomen, chest roentgenogram, whole body computed tomography, and bone scintigraphy showed no evidence of systemic involvement. The diagnosis of primary orbital neuroblastoma was made, and the child was subjected to chemotherapy followed by rapid melting of the tumor. Neuroblastoma should be considered in the differential diagnosis of childhood orbital tumors.
authors.affiliation: Department of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
authors.forename: Muthukrishnan
authors.initials: M
authors.lastname: Vallinayagam
authors.forename: Vasudev Anand
authors.initials: VA
authors.lastname: Rao
authors.forename: Datta Gulnar
authors.initials: DG
authors.lastname: Pandian
authors.forename: John Davis
authors.initials: JD
authors.lastname: Akkara
authors.forename: Niruban
authors.initials: N
authors.lastname: Ganesan
mesh_terms: D001706:Biopsy; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009447:Neuroblastoma / Q000175:diagnosis*; D009918:Orbital Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed