title: Iron-catalyzed transfer hydrogenation of imines assisted by an iron-based Lewis acid.
abstract: An iron-catalyzed transfer hydrogenation of N-aryl and N-alkyl imines using isopropanol as the hydrogen donor is reported for the first time. A combination of two iron complexes serving different roles is the key for the success of this catalytic system. As a result, an environmentally friendly and precious metal-free transfer hydrogenation of imines has been developed. The use of a suitable co-catalyst as an activator not only led to efficient transfer hydrogenation, but also showed potential in enantioselective transformation.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Republic of Singapore. zhaoyu@nus.edu.sg.
authors.forename: Hui-Jie
authors.initials: HJ
authors.lastname: Pan
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Republic of Singapore. zhaoyu@nus.edu.sg.
authors.forename: Teng Wei
authors.initials: TW
authors.lastname: Ng
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Republic of Singapore. zhaoyu@nus.edu.sg.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhao