title: Giant mediastinal thymolipoma in a patient with Gardner's syndrome.
abstract: Gardner's syndrome is a hereditary disorder inherited as an autosomal dominant with high penetrance and variable expression that is caused by a mutation of the adenomatous polyposis coli gene. It is characterized by gastrointestinal polyps associated with multiple osteomas, dental anomalies, and skin and soft tissue tumors. We present a case of 30-year-old female patient with Gardner's syndrome who presented with a giant mediastinal thymolipoma. The tumor was completely excised through a bilateral posterolateral thoracotomy. There was no recurrence after 20 months of follow-up. We therefore suggest that physicians who regularly treat patients with Gardner's syndrome carefully examine for thoracic manifestations.
authors.affiliation: Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University Beijing, China.
authors.forename: Guotian
authors.initials: G
authors.lastname: Pei
authors.affiliation: Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University Beijing, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Han
authors.affiliation: Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University Beijing, China.
authors.forename: Shijie
authors.initials: S
authors.lastname: Zhou
authors.affiliation: Department of Thoracic Surgery, Beijing Chest Hospital, Capital Medical University Beijing, China.
authors.forename: Zhidong
authors.initials: Z
authors.lastname: Liu
keywords: Gardner syndrome; mediastinum; thymus tumor