title: Serum pentraxin-3 levels in acute stroke: No association with stroke prognosis.
abstract: BACKGROUND
  Stroke is the leading cause of serious disability. Estimating severity of the disease and early risk assessment is crucial. Several studies have been carried on and several biomarkers have been proposed in the literature for risk assessment and to estimate the stroke prognosis. In this study we assessed the association of predictors such as patient age, gender, stroke volume and NIHS scores on prognosis of stroke event. We investigated whether the serum pentraxin-3 levels are linked with stroke prognosis.
  
  
  METHODS
  Forty-four stroke patients without cardiovascular risk factors were included in this study. Initial NIHS scores, stroke volumes, serum pentraxin-3 levels and the data regarding the risk factors were collected in the first and seventh days of event. Association of predictors with final NIHS scores were investigated using multivariate regression model.
  
  
  RESULTS
  Initial NIHS score, initial and final stroke volumes were independently associated with final NIHS score whereas serum pentraxin-3 levels, whether acquired at the first or seventh day of stroke, were not associated with final NIHS score.
  
  
  CONCLUSIONS
  In stroke patients without cardiovascular, cardiopulmonary and infectious diseases, serum pentraxin-3 levels are not associated with stroke prognosis.
authors.affiliation: Section of Neurology, Regional Education and Research Hospital, Erzurum, Turkey. Electronic address: drmuson16@hotmail.com.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ceylan
authors.affiliation: Section of Radiology, Regional Education and Research Hospital, Erzurum, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Yalcin
authors.affiliation: Section of Neurology, Regional Education and Research Hospital, Erzurum, Turkey.
authors.forename: O Faruk
authors.initials: OF
authors.lastname: Bayraktutan
authors.affiliation: Department of Medical Biology, School of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Omer
authors.initials: O
authors.lastname: Atis
authors.affiliation: Department of Emergency Medicine, School of Medicine, Sitki Kocman University, Mugla, Turkey.
authors.forename: Ethem
authors.initials: E
authors.lastname: Acar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism*; D038524:Diffusion Magnetic Resonance Imaging; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D011379:Prognosis; D012044:Regression Analysis; D000683:Serum Amyloid P-Component / Q000378:metabolism*; D020521:Stroke / Q000097:blood* / Q000175:diagnosis / Q000628:therapy; D013997:Time Factors; D000099153:Pentraxins
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein; D000683:Serum Amyloid P-Component; D000099153:Pentraxins
keywords: Acute stroke; Pentraxin-3; Prognosis