title: A Clinical Picture of the Visual Outcome in Adamantiades-Behçet's Disease.
abstract: Adamantiades-Behçet's disease is a multisystemic vasculitis with multiorgan involvement. Ocular disorders occur often in this syndrome typically in the form of a relapsing-remitting panuveitis and vasculitis and can lead to blindness as one of its most disabling complications if left untreated. There are known risk factors related with the worst visual prognosis, which require early and intensive treatment in order to obtain a rapid suppression of inflammation and to prevent future relapses. The management strategy to avoid vision loss and blindness currently involves the use of local and systemic drugs including steroids and immunosuppressive and biologic agents. This review aims to demonstrate how the introduction and the use of biologic agents improves the visual outcome of patients with Adamantiades-Behçet's disease.
authors.affiliation: Department of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Figus
authors.affiliation: Department of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Posarelli
authors.affiliation: Department of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, Italy.
authors.forename: Timothy G
authors.initials: TG
authors.lastname: Albert
authors.affiliation: Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, 56100 Pisa, Italy.
authors.forename: Rosaria
authors.initials: R
authors.lastname: Talarico
authors.affiliation: Department of Surgical, Medical, Molecular Pathology and Department of Emergency, University of Pisa, 56100 Pisa, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Nardi
mesh_terms: D001528:Behcet Syndrome / Q000188:drug therapy* / Q000503:physiopathology; D001685:Biological Factors / Q000627:therapeutic use; D001766:Blindness / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D011379:Prognosis; D014792:Visual Acuity / Q000502:physiology*
chemical_list: D001685:Biological Factors; D007166:Immunosuppressive Agents