title: Study on the sorption process of triclosan on cationic microfibrillated cellulose and its antibacterial activity.
abstract: Cationic microfibrillated cellulose (CMFC), as one kind of cellulose-based materials, is widely used in many fields. In this work, it was functionalized with a traditional antibacterial agent (triclosan, TCS). The sorption process of TCS onto CMFC was expressed by kinetic and isotherm models. The results showed that there was a high correlation coefficient (R(2)>0.9) in the pseudo-second-order model and the isotherm models, indicating that CMFC had a good sorption capacity for TCS. The sorption type was chemisorption, and the reaction power was electrostatic interactions. The antibacterial activity of the assembled TCS/CMFC compound was tested by disk diffusion method, and it was found a higher antibacterial activity than CMFC alone (bigger inhibition zone diameters). Further, the functionalized TCS/CMFC compound was used in the fiber network during handsheets making, and it had a higher antibacterial rate than TCS alone (increase by 45.1% against Escherichia coli and by 54.8% against Staphylococcus aureus, respectively).
authors.affiliation: Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, PR China. Electronic address: hongjiezhang@tust.edu.cn.
authors.forename: Hongjie
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, PR China.
authors.forename: Xu
authors.initials: X
authors.lastname: Zeng
authors.affiliation: Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, PR China.
authors.forename: Jinglei
authors.initials: J
authors.lastname: Xie
authors.affiliation: Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, PR China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Li
authors.affiliation: Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, PR China.
authors.forename: Hailong
authors.initials: H
authors.lastname: Li
mesh_terms: D065966:Absorption, Physicochemical; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D014260:Triclosan / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D014260:Triclosan; D002482:Cellulose
keywords: Antibacterial activity; Cationic microfibrillated cellulose; Functionalization; Sorption models; Triclosan