title: The impact of off-pump surgery in end-organ function: practical end-points.
abstract: Most surgeons perform coronary bypass surgery with the aid of cardiopulmonary bypass, which inflicts a massive systemic inflammatory response to the body leading to adverse clinical outcome. In an attempt to make CABG less invasive, interest have been diverted to the off pump technique.The current review attempts to bring an insight onto the last ten years knowledge on the off-pump impact in end organ function, with an aim to draw some clear conclusions in order to allow practitioners to reflect on the subject.
authors.affiliation: Cardiothoracic Department, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland. hparissis@yahoo.co.uk.
authors.forename: Haralabos
authors.initials: H
authors.lastname: Parissis
authors.affiliation: Cardiothoracic Department, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland. simon.mbarushimana2@nhs.net.
authors.forename: Simon
authors.initials: S
authors.lastname: Mbarushimana
authors.affiliation: Cardiopulmonary Transplantation Department, Freeman Hospital, Newcastle Upon Tyne, NE7 7DN, UK. B.C.Ramesh@nuth.nhs.uk.
authors.forename: Bandigowdanapalya C
authors.initials: BC
authors.lastname: Ramesh
authors.affiliation: Cardiothoracic Department, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland. mond.woolley@gmail.com.
authors.forename: Mondrian
authors.initials: M
authors.lastname: Parissis
authors.affiliation: Cardiothoracic Department, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland. savvas.lampridis@gmail.com.
authors.forename: Savvas
authors.initials: S
authors.lastname: Lampridis
authors.affiliation: Cardiothoracic Department, Royal Victoria Hospital, Grosvenor Road, Belfast, BT12 6BA, Northern Ireland. pmhandu@icloud.com.
authors.forename: Peter
authors.initials: P
authors.lastname: Mhandu
authors.affiliation: Thoracic Department, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. basselalalao@yahoo.com.
authors.forename: Bassel
authors.initials: B
authors.lastname: Al-Alao
mesh_terms: D047549:Coronary Artery Bypass, Off-Pump / Q000379:methods*; D003324:Coronary Artery Disease / Q000503:physiopathology / Q000601:surgery*; D003326:Coronary Circulation / Q000502:physiology*; D006801:Humans; D009206:Myocardium / Q000378:metabolism*; D018384:Oxidative Stress