title: Viral Regulation of Cell Tropism in Human Cytomegalovirus.
abstract: The viral glycoproteins that decorate enveloped viruses play crucial roles in cell entry and in large part dictate the spectrum of cell types that a virus can infect. The identification in human cytomegalovirus (HCMV) of a viral endoplasmic reticulum (ER)-resident glycoprotein that regulates the composition of alternative viral envelope glycoprotein complexes raises the intriguing possibility that certain viruses might actively regulate the tropism of progeny virions to improve their fitness or to navigate through the host.
authors.affiliation: Department of Microbiology and Immunology and Center for Molecular and Tumor Virology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
authors.forename: Gang
authors.identifier: http://orcid.org/0000-0002-1441-7531
authors.initials: G
authors.lastname: Li
authors.affiliation: Department of Microbiology and Immunology and Center for Molecular and Tumor Virology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA jkamil@lsuhsc.edu.
authors.forename: Jeremy P
authors.identifier: http://orcid.org/0000-0001-8422-7656
authors.initials: JP
authors.lastname: Kamil
mesh_terms: D003587:Cytomegalovirus / Q000502:physiology*; D003586:Cytomegalovirus Infections / Q000821:virology*; D004721:Endoplasmic Reticulum / Q000378:metabolism / Q000821:virology; D006801:Humans; D014760:Viral Fusion Proteins / Q000378:metabolism; D014764:Viral Proteins / Q000378:metabolism*; D056189:Viral Tropism
chemical_list: C000598883:UL148 protein, human cytomegalovirus; D014760:Viral Fusion Proteins; D014764:Viral Proteins