title: Uptake, translocation and biotransformation kinetics of BDE-47, 6-OH-BDE-47 and 6-MeO-BDE-47 in maize (Zea mays L.).
abstract: This study presents a detailed kinetic investigation on the uptake, acropetal translocation and transformation of BDE-47, 6-OH-BDE-47 and 6-MeO-BDE-47 in maize (Zea mays L.) by hydroponic exposure. Root uptake followed the order: BDE-47 > 6-MeO-BDE-47 > 6-OH-BDE-47, while 6-OH-BDE-47 was the most prone to acropetal translocation. Debromination rates of BDE-47 were 1.31 and 1.46 times greater than the hydroxylation and methoxylation rates, respectively. Transformation from BDE-47 to lower brominated OH/MeO-PBDEs occurred mainly through debromination first followed by hydroxylation or methoxylation. There was no transformation from 6-OH-BDE-47 or 6-MeO-BDE-47 to PBDEs. Methylation rate of 6-OH-BDE-47 was twice as high as that of 6-MeO-BDE-47 hydroxylation, indicating methylation of 6-OH-BDE-47 was easier and more rapid than hydroxylation of 6-MeO-BDE-47. Debromination and isomerization were potential metabolic pathways for 6-OH-BDE-47 and 6-MeO-BDE-47 in maize. This study provides important information for better understanding the mechanism on plant uptake and transformation of PBDEs.
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing, 100085, China.
authors.forename: Xuehui
authors.initials: X
authors.lastname: Xu
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing, 100085, China.
authors.forename: Bei
authors.initials: B
authors.lastname: Wen
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing, 100085, China.
authors.forename: Honglin
authors.initials: H
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing, 100085, China; Department of Environmental Sciences, College of Urban and Environmental Sciences, Northwest University, Xi'an, 710027, China.
authors.forename: Sen
authors.initials: S
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing, 100085, China.
authors.forename: Ruixia
authors.initials: R
authors.lastname: Han
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, P.O. Box 2871, Beijing, 100085, China. Electronic address: szzhang@rcees.ac.cn.
authors.forename: Shuzhen
authors.initials: S
authors.lastname: Zhang
mesh_terms: D000840:Anisoles / Q000032:analysis / Q000378:metabolism*; D001711:Biotransformation; D055768:Halogenated Diphenyl Ethers / Q000032:analysis / Q000378:metabolism*; D054879:Halogenation; D018527:Hydroponics; D006900:Hydroxylation; D007700:Kinetics; D053858:Metabolic Networks and Pathways; D018517:Plant Roots / Q000737:chemistry / Q000378:metabolism; D011075:Polybrominated Biphenyls / Q000032:analysis / Q000378:metabolism*; D003313:Zea mays / Q000737:chemistry / Q000254:growth & development / Q000378:metabolism*
chemical_list: C496823:2-(2',4'-dibromophenoxy)-3,5-dibromoanisole; C580599:6-OH-BDE-47; D000840:Anisoles; D055768:Halogenated Diphenyl Ethers; D011075:Polybrominated Biphenyls; C511295:2,2',4,4'-tetrabromodiphenyl ether
keywords: Biotransformation; Maize; MeO-PBDEs; OH-PBDEs; PBDEs