title: A case of methylprednisolone treatment for interstitial pneumonia induced by gefitinibin.
abstract: In this case, an old man was diagnosed as lung cancer, clinical stage IV. In order to alleviate cancer, this patient was treated with gefitinib. Three months later, symptoms such as a significant weakness, chest tightness and shortness of breath after sports arised and intensifying. Implosive therapy with high dose methylprednisolone is used to control the weakness caused by gefitinib. Eight days after treatment, patient's condition significantly improved. The use of methylprednisolone can effectively treat interstitial pneumonia induced by gefitinibin, help patients get better from critical condition such as type I respiratory failure. This new discovery is a good guidance for clinical treatment of gefitinibin caused interstitial pneumonia.
authors.affiliation: Department of Oncology, Shanghai Jiading District Central Hospital Shanghai 201800, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Yan
authors.affiliation: Department of Oncology, Shanghai Jiading District Central Hospital Shanghai 201800, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Oncology, Shanghai Jiading District Central Hospital Shanghai 201800, China.
authors.forename: Qinfang
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Department of Oncology, Shanghai Jiading District Central Hospital Shanghai 201800, China.
authors.forename: Xiaoou
authors.initials: X
authors.lastname: Chen
authors.affiliation: Department of Oncology, Shanghai Jiading District Central Hospital Shanghai 201800, China ; Departments of Adiotherapy, Sixth People's Hospital Affiliated to Shanghai Jiaotong University Shanghai 200233, China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Yu
keywords: Methylprednisolone; gefitinibin; interstitial pneumonia