title: A Delphi consensus study on salvage brachytherapy for prostate cancer relapse after radiotherapy, a Uro-GEC study.
abstract: OBJECTIVE
  Patients treated with low radiotherapy dose or treated at young age are at a risk of developing local relapse. Although data are preliminary, brachytherapy seems an attractive treatment option for recurrent prostate cancer after previous radiotherapy. Therefore, the UroGEC group of the GEC-ESTRO conducted a Delphi study, to explore expert opinion on the management of salvage prostate brachytherapy.
  
  
  METHODS
  For this study, a series of digital questionnaires were sent, which enabled data collection from an international group of experienced participants. Consensus was defined as 80% agreement for each question.
  
  
  RESULTS
  Eighteen experts completed all rounds of the Delphi study. After the final round consensus was reached on 17 out of 38 (45%) questions. Consensus was reached in 52% of questions about patient selection, in 50% of the questions about diagnostic tests and in 22% of the questions on performing salvage prostate brachytherapy.
  
  
  CONCLUSIONS
  The group was able to find consensus on less than half of the questions. Most consensus was reached on topics involving patient selection and diagnostic tests, where participants could build on their experience of daily practice. However, the way to perform the salvage treatment is less established and results in more disagreement between participants.
authors.affiliation: Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands. Electronic address: m.kaljouw@amc.uva.nl.
authors.forename: Emmie
authors.initials: E
authors.lastname: Kaljouw
authors.affiliation: Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Bradley R
authors.initials: BR
authors.lastname: Pieters
authors.affiliation: Interdisciplinary Brachytherapy Unit, University of Lübeck, Germany.
authors.forename: György
authors.initials: G
authors.lastname: Kovács
authors.affiliation: Mount Vernon Cancer Centre, UK.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Hoskin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000379:methods*; D032921:Consensus; D003697:Delphi Technique; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000532:radiotherapy*; D018579:Patient Selection; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D016879:Salvage Therapy / Q000379:methods
chemical_list: D017430:Prostate-Specific Antigen
keywords: Delphi study; Prostate neoplasms; Recurrent prostate cancer; Salvage brachytherapy