title: Synthesis, Structural Characterization of a Novel Ferrocene Derivative and Preliminarily Anticancer Activity.
abstract: A novel structure of ferrocene derivative 1 was synthesized with cyanuric chloride and ferrocenemethanol as starting materials. The synthesized compound was fully characterized using 1H NMR, 13C NMR, MS and XRD. Subsequently, the in vitro anticancer effect against A549, HCT116 and MCF-7 cell lines was preliminarily evaluated by the MTT method. The result showed that this compound exhibits good cytotoxic effect on A549, HCT116 and MCF-7 cell lines.
authors.affiliation: Xiamen Institute of Rare-earth Materials, Chinese Academy of Sciences, Xiamen, 361021, China. jpyong@fjirsm.ac.cn.
authors.forename: Jianping
authors.initials: J
authors.lastname: Yong
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Wu
authors.forename: Jianzhen
authors.initials: J
authors.lastname: Liao
authors.affiliation: czlu@fjirsm.ac.cn.
authors.forename: Canzhong
authors.initials: C
authors.lastname: Lu
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Liu
mesh_terms: D000072283:A549 Cells; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D005296:Ferrous Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D045325:HCT116 Cells; D006801:Humans; D061986:MCF-7 Cells; D066244:Proton Magnetic Resonance Spectroscopy; D014227:Triazines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D005296:Ferrous Compounds; D014227:Triazines