title: Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
abstract: Hair health is an important attribute to women globally--specifically attributes such as shine, healthy tips, frizz-free and strength. However, many women will claim to have at least moderate hair damage caused by habits and practices such as washing, combing and brushing, use of heated implements and regular use of chemical treatments. The objective of this work was to investigate two mechanisms of damage--hair colouring and UV exposure--where oxidative processes are involved. The role of copper in these oxidative processes was then investigated: its presence in hair and its consequent impact on hair damage via free radical formation. Finally, the role of chelants N,N'-ethylene diamine disuccinic acid (EDDS) and histidine in preventing free radical formation was investigated and shown to improve hair health.
authors.affiliation: The Procter & Gamble Company, Mason Business Center, 8700 Mason Montgomery Road, Mason, OH, 45040, U.S.A.
authors.forename: J M
authors.initials: JM
authors.lastname: Marsh
authors.affiliation: The Procter & Gamble Company, Mason Business Center, 8700 Mason Montgomery Road, Mason, OH, 45040, U.S.A.
authors.forename: M G
authors.initials: MG
authors.lastname: Davis
authors.affiliation: The Procter & Gamble Company, Mason Business Center, 8700 Mason Montgomery Road, Mason, OH, 45040, U.S.A.
authors.forename: R L
authors.initials: RL
authors.lastname: Lucas
authors.affiliation: The Procter & Gamble Company, Mason Business Center, 8700 Mason Montgomery Road, Mason, OH, 45040, U.S.A.
authors.forename: R
authors.initials: R
authors.lastname: Reilman
authors.affiliation: The Procter & Gamble Company, Mason Business Center, 8700 Mason Montgomery Road, Mason, OH, 45040, U.S.A.
authors.forename: P B
authors.initials: PB
authors.lastname: Styczynski
authors.affiliation: The Procter & Gamble Company, Mason Business Center, 8700 Mason Montgomery Road, Mason, OH, 45040, U.S.A.
authors.forename: C
authors.initials: C
authors.lastname: Li
authors.affiliation: The Procter & Gamble Company, Mason Business Center, 8700 Mason Montgomery Road, Mason, OH, 45040, U.S.A.
authors.forename: M
authors.initials: M
authors.lastname: Mamak
authors.affiliation: Center for Electron Microscopy and Analysis, The Ohio State University, 1305 Kinnear Road, Columbus, OH, 43212, U.S.A.
authors.forename: D W
authors.initials: DW
authors.lastname: McComb
authors.affiliation: Center for Electron Microscopy and Analysis, The Ohio State University, 1305 Kinnear Road, Columbus, OH, 43212, U.S.A.
authors.forename: R E A
authors.initials: RE
authors.lastname: Williams
authors.affiliation: Procter & Gamble Service GmbH, Berliner Allee 65, D-64274, Darmstadt, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Godfrey
authors.affiliation: Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
authors.forename: K R
authors.initials: KR
authors.lastname: Navqi
authors.affiliation: Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
authors.forename: V
authors.initials: V
authors.lastname: Chechik
mesh_terms: D005260:Female; D006197:Hair / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D006202:Hair Dyes; D006801:Humans; D018384:Oxidative Stress; D014466:Ultraviolet Rays
chemical_list: D006202:Hair Dyes
keywords: N,N’-ethylenediamine disuccinic acid; TEM; UV; X-ray energy-dispersive spectroscopy; chelants; copper; free radicals; hair; hair colouring; histidine; mass spectrometry