title: Dietary supplements and pediatric non-alcoholic fatty liver disease: Present and the future.
abstract: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children. High prevalence of pediatric obesity and sedentary lifestyle has augmented the incidence of NAFLD in children. Obesity is associated with an increased risk of NAFLD through various mechanisms such as intensification of insulin resistance and increased levels of inflammatory markers. There is no approved medical intervention for treatment of pediatric NAFLD; the only proven strategy in management of pediatric NAFLD is lifestyle modification. Recently, the effects of nutritional supplements have been examined in the management of pediatric NAFLD. The purpose of this review is to summarize the studies evaluating the effects of nutritional supplements on pediatric NAFLD and explain the future direction in this field.
authors.affiliation: Mehran Rahimlou, Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran 1948141556, Iran.
authors.forename: Mehran
authors.initials: M
authors.lastname: Rahimlou
authors.affiliation: Mehran Rahimlou, Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran 1948141556, Iran.
authors.forename: Hoda
authors.initials: H
authors.lastname: Ahmadnia
authors.affiliation: Mehran Rahimlou, Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran 1948141556, Iran.
authors.forename: Azita
authors.initials: A
authors.lastname: Hekmatdoost
keywords: Diet; Dietary supplement; Fatty liver; Nutrition; Pediatric non-alcoholic fatty liver disease