title: A novel aptasensor for thrombin detection based on alkaline phosphatase decorated ZnO/Pt nanoflowers as signal amplifiers.
abstract: To remedy the problems caused by the introduction of an additional electron mediator and realize signal amplification, a new strategy has been presented to construct an electrochemical aptasensor for thrombin detection based on the cascade electrocatalysis of alkaline phosphatase (ALP) and Pt nanoparticle (PtNP)-functionalized ZnO nanoflowers.
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
authors.forename: J J
authors.initials: JJ
authors.lastname: Lv
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
authors.forename: Z H
authors.initials: ZH
authors.lastname: Yang
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhuo
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
authors.forename: R
authors.initials: R
authors.lastname: Yuan
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. yuanruo@swu.edu.cn yqchai@swu.edu.cn.
authors.forename: Y Q
authors.initials: YQ
authors.lastname: Chai
mesh_terms: D000469:Alkaline Phosphatase / Q000737:chemistry*; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D004563:Electrochemistry; D004566:Electrodes; D053758:Nanoparticles / Q000737:chemistry*; D012815:Signal Processing, Computer-Assisted; D013917:Thrombin / Q000032:analysis*; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D052157:Aptamers, Nucleotide; D000469:Alkaline Phosphatase; D013917:Thrombin; D015034:Zinc Oxide