title: [Nasopharyngeal Hib Carriage Among Healthy Children Attending Daycare Centers in Yokohama After One Year of a Publicly Funded Vaccine Program].
abstract: Yokohama city started a regular, free vaccine program for Haemophilus influenzae type b (Hib) from February of 2011. This study was completed to verify the effectiveness of the vaccine on the nasopharyngeal Hib carriage among healthy children attending daycare centers in the Isogo area. The research was conducted during the late spring (Jun--Jul) and fall (Oct-Nov) of 2012. There was a significant decrease in the Hib carriage rate (spring 8.8%, fall 1.6%). During this period there was no increase in the Hib vaccine coverage. The Hib carriage rate of each daycare center was 0-18.4% in spring and 0-4.9% in fall. There was no significant relationship between the rate of non immunized children and that of Hib carriage. This improvement in nasopharyngeal Hib carriage shows the impact of community immunity.
authors.forename: Ayako
authors.initials: A
authors.lastname: Saito
authors.forename: Hiroko
authors.initials: H
authors.lastname: Sumita
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Minohara
authors.forename: Shinji
authors.initials: S
authors.lastname: Fujita
authors.forename: Shigeyoshi
authors.initials: S
authors.lastname: Yazaki
authors.forename: Miyoshi
authors.initials: M
authors.lastname: Kitamura
authors.forename: Shigehiko
authors.initials: S
authors.lastname: Kawai
authors.forename: Kazumi
authors.initials: K
authors.lastname: Kamata
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Oota
authors.forename: Mikiko
authors.initials: M
authors.lastname: Yamada
authors.forename: Yuko
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Takeyasu
mesh_terms: D016667:Bacterial Capsules / Q000276:immunology*; D001428:Bacterial Vaccines / Q000627:therapeutic use*; D002656:Child Day Care Centers; D002675:Child, Preschool; D006192:Haemophilus Infections / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control*; D018073:Haemophilus Vaccines / Q000276:immunology*; D019741:Haemophilus influenzae type b / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007564:Japan; D014611:Vaccination
chemical_list: D001428:Bacterial Vaccines; D018073:Haemophilus Vaccines; C044237:Haemophilus influenzae type b polysaccharide vaccine