title: Extraction of quinolones from milk samples using bentonite/magnetite nanoparticles before determination by high-performance liquid chromatography with fluorimetric detection.
abstract: In this work, bentonite magnetic nanoparticles synthesized by a typical coprecipitation method were used as the adsorbent for the magnetic solid-phase extraction of six quinolones (ciprofloxacin, difloxacin, enrofloxacin, norfloxacin, sarafloxacin, and lomefloxacin) from milk samples followed by high-performance liquid chromatography with fluorimetric detection. Under the optimized conditions, the linear quantitation range for the six quinolones was 0.3-200 ng/mL, and the correlation coefficients of the calibration curves ranged from 0.9994 to 0.9999. The detection limit of the method was 0.1 ng/mL. Recoveries of quinolones from pure and low-fat spiked milk samples varied from 80.4 to 92.7% and from 81.3 to 93.5%, respectively. These results demonstrated that the proposed method for the determination of six quinolones in milk samples was rapid, reliable, and efficient.
authors.affiliation: Analyzing and Testing Center of Guangzhou Institute of Chemistry, Chinese Academy of Sciences, Guangzhou, P. R. China.
authors.forename: Tao
authors.initials: T
authors.lastname: Jin
authors.affiliation: School of Chemistry and Material Science, Shanxi Normal University, Shanxi Linfen, P. R. China.
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.affiliation: School of Chemistry and Material Science, Shanxi Normal University, Shanxi Linfen, P. R. China.
authors.forename: Nannan
authors.initials: N
authors.lastname: Gao
authors.affiliation: Analyzing and Testing Center of Guangzhou Institute of Chemistry, Chinese Academy of Sciences, Guangzhou, P. R. China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Chen
authors.affiliation: Analyzing and Testing Center of Guangzhou Institute of Chemistry, Chinese Academy of Sciences, Guangzhou, P. R. China.
authors.forename: Huajie
authors.initials: H
authors.lastname: Lai
authors.affiliation: School of Chemistry and Material Science, Shanxi Normal University, Shanxi Linfen, P. R. China.
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Zheng
authors.affiliation: School of Chemistry and Material Science, Shanxi Normal University, Shanxi Linfen, P. R. China.
authors.forename: Liming
authors.initials: L
authors.lastname: Du
mesh_terms: D000327:Adsorption; D001546:Bentonite / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005470:Fluorometry / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D058185:Magnetite Nanoparticles; D008855:Microscopy, Electron, Scanning; D015203:Reproducibility of Results; D052617:Solid Phase Microextraction
chemical_list: D058185:Magnetite Nanoparticles; D001546:Bentonite
keywords: High-performance liquid chromatography; Magnetic solid-phase extraction; Milk; Quinolones