title: Giant Septic Lymphadenitis with Marked Gas Formation Caused by Bacteroides fragilis in a Patient with Adult T-cell Leukemia/lymphoma.
abstract: Adult T-cell leukemia/lymphoma (ATL) sometimes causes opportunistic infections. A 53-year-old woman with systemic lymphadenopathies was diagnosed with ATL by inguinal lymph node biopsies and underwent oral chemotherapy. Two months later, high grade fever, lower abdominal pain and lymphadenopathy recurred. Computed tomography revealed the presence of lymphadenopathy with marked gas formation in the pelvic lesion. Blood cultures were suggestive of septic lymphadenitis by Bacteroides fragilis (BF). This represents the first demonstration of giant lymphadenitis with gas formation caused by BF in a patient with ATL. Notably, septic lymphadenitis is pivotal in the differential diagnosis of systemic lymphadenopathy in ATL.
authors.affiliation: Division of Endocrinology, Diabetes and Metabolism, Hematology and Rheumatology, Second Department of Internal Medicine, Graduate School of Medicine, University of the Ryukyus, Japan.
authors.forename: Takeaki
authors.initials: T
authors.lastname: Tomoyose
authors.forename: Sawako
authors.initials: S
authors.lastname: Nakachi
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Nishi
authors.forename: Kazuho
authors.initials: K
authors.lastname: Morichika
authors.forename: Iori
authors.initials: I
authors.lastname: Tedokon
authors.forename: Keita
authors.initials: K
authors.lastname: Tamaki
authors.forename: Natsuki
authors.initials: N
authors.lastname: Shimabukuro
authors.forename: Taeko
authors.initials: T
authors.lastname: Hanashiro
authors.forename: Hironori
authors.initials: H
authors.lastname: Samura
authors.forename: Takuya
authors.initials: T
authors.lastname: Fukushima
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Masuzaki
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D001442:Bacteroides Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D001441:Bacteroides fragilis / Q000302:isolation & purification*; D001706:Biopsy; D003520:Cyclophosphamide; D003937:Diagnosis, Differential; D004317:Doxorubicin; D005260:Female; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008198:Lymph Nodes / Q000473:pathology; D008199:Lymphadenitis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D011241:Prednisone; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014750:Vincristine
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone