title: Examination of the interaction of different lighting conditions and chronic mild stress in animal model.
abstract: We examined the effects of different shift work schedules and chronic mild stress (CMS) on mood using animal model. The most common international shift work schedules in nursing were applied by three groups of Wistar-rats and a control group with normal light-dark cycle. One subgroup from each group was subjected to CMS. Levels of anxiety and emotional life were evaluated in light-dark box. Differences between the groups according to independent and dependent variables were examined with one- and two-way analysis of variance, with a significance level defined at p < 0.05. Interaction of lighting regimen and CMS was proved to be significant according to time spent in the light compartment and the average number of changes between the light and dark compartments. Results of our examination confirm that the changes of lighting conditions evocate anxiety more prominently than CMS. No significant differences were found between the results of the low rotating group and the control group, supposing that this schedule is the least harmful to health. Our results on the association between the use of lighting regimens and the level of CMS provide evidence that the fast rotating shift work schedule puts the heaviest load on the organism of animals.
authors.affiliation: Institute of Emergency Care and Pedagogy of Health, Faculty of Health Sciences, University of Pécs , Pécs , Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Muller
authors.affiliation: Institute of Nursing Sciences, Basic Health Sciences and Health Visiting, Faculty of Health Sciences, University of Pécs , Pécs , Hungary.
authors.forename: N
authors.initials: N
authors.lastname: Gal
authors.affiliation: Institute of Emergency Care and Pedagogy of Health, Faculty of Health Sciences, University of Pécs , Pécs , Hungary.
authors.forename: J
authors.initials: J
authors.lastname: Betlehem
authors.affiliation: Institute of Nursing Sciences, Basic Health Sciences and Health Visiting, Faculty of Health Sciences, University of Pécs , Pécs , Hungary.
authors.forename: N
authors.initials: N
authors.lastname: Fuller
authors.affiliation: Institute of Physiotherapy and Sport Sciences, Faculty of Health Sciences , University of Pécs, Pécs , Hungary.
authors.forename: P
authors.initials: P
authors.lastname: Acs
authors.affiliation: Institute of Diagnostics, Faculty of Health Sciences, University of Pécs , Pécs , Hungary.
authors.forename: G L
authors.initials: GL
authors.lastname: Kovacs
authors.affiliation: Institute of Nursing Sciences, Basic Health Sciences and Health Visiting, Faculty of Health Sciences, University of Pécs , Pécs , Hungary.
authors.forename: K
authors.initials: K
authors.lastname: Fusz
authors.affiliation: Department of Anatomy, Medical School, University of Pécs , Pécs , Hungary.
authors.forename: R
authors.initials: R
authors.lastname: Jozsa
authors.affiliation: Institute of Nursing Sciences, Basic Health Sciences and Health Visiting, Faculty of Health Sciences, University of Pécs , Pécs , Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Olah
mesh_terms: D000818:Animals; D001007:Anxiety / Q000209:etiology / Q000523:psychology; D001522:Behavior, Animal; D004644:Emotions; D006799:Housing, Animal; D008029:Lighting / Q000379:methods*; D009043:Motor Activity; D017440:Photoperiod; D017208:Rats, Wistar; D012720:Severity of Illness Index; D013315:Stress, Psychological / Q000175:diagnosis / Q000209:etiology / Q000523:psychology*; D013997:Time Factors
keywords: animal models; anxiety; chronic mild stress; light-dark box test; modelling of shift work; shift work