title: Associations between Carotid Artery Plaque Score, Carotid Hemodynamics and Coronary Heart Disease.
abstract: BACKGROUND
  The carotid artery plaque score (PS) is an independent predictor of Coronary Heart Disease (CHD). This study aims to evaluate the combination of PS and carotid hemodynamics to predict CHD.
  
  
  METHODS
  A total of 476 patients who underwent carotid ultrasonography and coronary angiography were divided into two groups depending on the presence of CHD. PS, carotid intima-media thickness, and carotid blood flow were measured. Receiver operating characteristic curve analysis was performed to establish the best prediction model for CHD presence.
  
  
  RESULTS
  Age, sex, carotid intima-media thickness of internal carotid artery and carotid bifurcation, PS, peak systolic velocity (PSA) of right internal carotid artery (RICA), and most resistance index data were significantly related with the presence of CHD. The area under the curve for a collective model, which included factors of the PS, carotid hemodynamics and age, was significantly higher than the other model. Age, PS, and PSA of RICA were significant contributors for predicting CHD presence.
  
  
  CONCLUSIONS
  The model of PS and PSA of RICA has greater predictive value for CHD than PS alone. Adding age to PS and PSA of RICA further improves predictive value over PS alone.
authors.affiliation: Department of Medical Ultrasonics, Ma'anshan People's Hospital, Ma'anshan 243000, China. zhhp1216@sina.com.
authors.forename: Huiping
authors.initials: H
authors.lastname: Zhang
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241000, China. lmxsnow11@sina.com.
authors.forename: Mengxue
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department of Medical Ultrasonics, Ma'anshan People's Hospital, Ma'anshan 243000, China. rtt7219@sina.com.
authors.forename: Tiantian
authors.initials: T
authors.lastname: Ren
authors.affiliation: Department of Medical Ultrasonics, Ma'anshan People's Hospital, Ma'anshan 243000, China. wangxq0314@sina.com.
authors.forename: Xiangqian
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Medical Ultrasonics, Ma'anshan People's Hospital, Ma'anshan 243000, China. ldd1020@sina.com.
authors.forename: Dandan
authors.initials: D
authors.lastname: Liu
authors.affiliation: Department of Medical Ultrasonics, Ma'anshan People's Hospital, Ma'anshan 243000, China. xml7498@sina.com.
authors.forename: Mingliang
authors.initials: M
authors.lastname: Xu
authors.affiliation: Center of Clinical Laboratory, Ma'anshan Medical Group, Ma'anshan 243000, China. e76402664@sina.com.
authors.forename: LingFei
authors.initials: L
authors.lastname: Han
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241000, China. wzwwnmc@sina.com.
authors.forename: Zewei
authors.initials: Z
authors.lastname: Wu
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241000, China. haiboli89@gmali.com.
authors.forename: Haibo
authors.initials: H
authors.lastname: Li
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241000, China. kutuomonk@foxmail.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241000, China. wyf@wnmc.edu.cn.
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Wen
authors.affiliation: School of Food Science, Guangdong Pharmaceutical University, Zhongshan 528458, China. wsun3@tulane.edu.|School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA. wsun3@tulane.edu.
authors.forename: Wenjie
authors.initials: W
authors.lastname: Sun
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity; D059168:Carotid Intima-Media Thickness; D016893:Carotid Stenosis / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D002681:China; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D012307:Risk Factors; D012737:Sex Factors
keywords: carotid intima-media thickness; carotid ultrasonography; coronary angiograph