title: Facial emotion recognition in alcohol and substance use disorders: A meta-analysis.
abstract: People with alcohol and substance use disorders (AUDs/SUDs) show worse facial emotion recognition (FER) than controls, though magnitude and potential moderators remain unknown. The aim of this meta-analysis was to estimate the association between AUDs, SUDs and FER impairment. Electronic databases were searched through April 2015. Pooled analyses were based on standardized mean differences between index and control groups with 95% confidence intervals, weighting each study with random effects inverse variance models. Risk of publication bias and role of potential moderators, including task type, were explored. Nineteen of 70 studies assessed for eligibility met the inclusion criteria, comprising 1352 individuals, of whom 714 (53%) had AUDs or SUDs. The association between substance related disorders and FER performance showed an effect size of -0.67 (-0.95, -0.39), and -0.65 (-0.93, -0.37) for AUDs and SUDs, respectively. There was no publication bias and subgroup and sensitivity analyses based on potential moderators confirmed core results. Future longitudinal research should confirm these findings, clarifying the role of specific clinical issues of AUDs and SUDs.
authors.affiliation: Department of Surgery and Translational Medicine, University of Milano Bicocca, Via Cadore 48, 20900 Monza (MB), Italy; PhD Program in Neuroscience, University of Milano Bicocca, Via Cadore 48, 20900 Monza (MB), Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Castellano
authors.affiliation: Department of Surgery and Translational Medicine, University of Milano Bicocca, Via Cadore 48, 20900 Monza (MB), Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Bartoli
authors.affiliation: Department of Surgery and Translational Medicine, University of Milano Bicocca, Via Cadore 48, 20900 Monza (MB), Italy. Electronic address: cristina.crocamo@unimib.it.
authors.forename: Cristina
authors.initials: C
authors.lastname: Crocamo
authors.affiliation: Department of Surgery and Translational Medicine, University of Milano Bicocca, Via Cadore 48, 20900 Monza (MB), Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Gamba
authors.affiliation: Department of Surgery and Translational Medicine, University of Milano Bicocca, Via Cadore 48, 20900 Monza (MB), Italy.
authors.forename: Martina
authors.initials: M
authors.lastname: Tremolada
authors.affiliation: Department of Surgery and Translational Medicine, University of Milano Bicocca, Via Cadore 48, 20900 Monza (MB), Italy.
authors.forename: Jacopo
authors.initials: J
authors.lastname: Santambrogio
authors.affiliation: Department of Surgery and Translational Medicine, University of Milano Bicocca, Via Cadore 48, 20900 Monza (MB), Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Clerici
authors.affiliation: Division of Psychiatry, University College London, 6th Floor, Maple House, 149 Tottenham Court Road, London W1T 7NF, UK.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Carrà
mesh_terms: D000428:Alcohol Drinking / Q000009:adverse effects*; D000438:Alcohols / Q000009:adverse effects*; D001835:Body Weight / Q000187:drug effects; D004644:Emotions / Q000502:physiology*; D006801:Humans; D021641:Recognition, Psychology / Q000502:physiology*; D019966:Substance-Related Disorders / Q000209:etiology*
chemical_list: D000438:Alcohols
keywords: Alcohol-related disorders; Facial expression; Meta-analysis; Substance-related disorders