title: Immunotherapy for Infectious Diseases: Past, Present, and Future.
abstract: Passive immunotherapy for established infections, as opposed to active immunization to prevent disease, remains a tiny niche in the world of antimicrobial therapies. Many of the passive immunotherapies currently available are directed against bacterial toxins, such as botulism, or are intended for agents of bioterrorism such as anthrax, which fortunately has remained rare. The emergence of Ebola virus and multi-drug resistant pathogens, however, may breathe new life into the immunotherapy field as researchers seek non-antibiotic interventions for infectious diseases.
authors.affiliation: a Division of Infectious Diseases , University at Buffalo , Buffalo , NY 14215 , USA.
authors.forename: Akshay
authors.initials: A
authors.lastname: Manohar
authors.affiliation: a Division of Infectious Diseases , University at Buffalo , Buffalo , NY 14215 , USA.
authors.forename: Jasmine
authors.initials: J
authors.lastname: Ahuja
authors.affiliation: a Division of Infectious Diseases , University at Buffalo , Buffalo , NY 14215 , USA.
authors.forename: John K
authors.initials: JK
authors.lastname: Crane
mesh_terms: D000818:Animals; D000906:Antibodies / Q000378:metabolism*; D001408:Bacillus anthracis / Q000276:immunology*; D001427:Bacterial Toxins / Q000276:immunology; D023482:Bioterrorism / Q000517:prevention & control*; D016207:Cytokines / Q000276:immunology / Q000378:metabolism*; D029043:Ebolavirus / Q000276:immunology*; D006801:Humans; D007116:Immunization, Passive; D007239:Infections / Q000276:immunology / Q000628:therapy*; D014764:Viral Proteins / Q000276:immunology
chemical_list: D000906:Antibodies; D001427:Bacterial Toxins; D016207:Cytokines; D014764:Viral Proteins
keywords: Antiserum; Iditarod race; immune globulin; passive immunity