title: [Spatial clustering of hand-foot-mouth disease in Gansu, 2012].
abstract: OBJECTIVE
  The purpose of this study was to explore the spatial distribution and spatial clustering of hand-foot-mouth disease (HFMD) in Gansu, 2012.
  
  
  METHODS
  Spatial autocorrelation and Spatial scanning analysis were used to conduct spatial statistical analyses for the HFMD at the county/district level.
  
  
  RESULTS
  HFMD cases did not show a random distribution but with significant spatial aggregation. When Local Autocorrelation analysis was applied at the county/district level, with nine hot spot areas as Jiayuguan, Yumen, Dunhuang, Jinta, Suzhou, Chengguan, Anning, Xigu and Gaolan, were discovered. Four statistically significant HFMD clusters were identified by spatial scan statistics.
  
  
  CONCLUSIONS
  HFMD was noticed geographically clustered in Gansu in 2012. Results from this study indicated that the spatial autocorrelation and spatial scanning analysis could effectively detect the areas which presenting significant clusters. Cluster Detection System (CDS) could provide evidence for the development of an effective measure concerning the prevention and control of HFMD.
authors.affiliation: School of Public Health, Lanzhou University, Lanzhou 730000, China.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Ren
authors.affiliation: School of Public Health, Lanzhou University, Lanzhou 730000, China.
authors.forename: Yana
authors.initials: Y
authors.lastname: Bai
authors.affiliation: Gansu Provincial Center for Disease Control and Prevention.
authors.forename: Xinfeng
authors.initials: X
authors.lastname: Liu
authors.affiliation: School of Public Health, Lanzhou University, Lanzhou 730000, China.
authors.forename: Juansheng
authors.initials: J
authors.lastname: Li
authors.affiliation: Gansu Provincial Center for Disease Control and Prevention.
authors.forename: Yunhe
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: School of Public Health, Lanzhou University, Lanzhou 730000, China.
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Liu
authors.affiliation: Gansu Provincial Center for Disease Control and Prevention.
authors.forename: Dongpeng
authors.initials: D
authors.lastname: Liu
authors.affiliation: School of Public Health, Lanzhou University, Lanzhou 730000, China.
authors.forename: Xiping
authors.initials: X
authors.lastname: Shen
authors.affiliation: School of Public Health, Lanzhou University, Lanzhou 730000, China.
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Hu
authors.affiliation: School of Public Health, Lanzhou University, Lanzhou 730000, China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Pei
authors.affiliation: Gansu Provincial Center for Disease Control and Prevention; Email: ccdcusc101@163.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Meng
mesh_terms: D002681:China / Q000453:epidemiology; D016000:Cluster Analysis; D006232:Hand, Foot and Mouth Disease / Q000453:epidemiology*; D006801:Humans; D062206:Spatial Analysis