title: Cementation of Glass-Ceramic Posterior Restorations: A Systematic Review.
abstract: OBJECTIVE
  The aim of this comprehensive review is to systematically organize the current knowledge regarding the cementation of glass-ceramic materials and restorations, with an additional focus on the benefits of Immediate Dentin Sealing (IDS).
  
  
  METHODS
  An extensive literature search concerning the cementation of single-unit glass-ceramic posterior restorations was conducted in the databases of MEDLINE (Pubmed), CENTRAL (Cochrane Central Register of Controlled Trials), and EMBASE. To be considered for inclusion, in vitro and in vivo studies should compare different cementation regimes involving a "glass-ceramic/cement/human tooth" complex.
  
  
  CONCLUSIONS
  88 studies were included in total. The in vitro data were organized according to the following topics: (micro)shear and (micro)tensile bond strength, fracture strength, and marginal gap and integrity. For in vivo studies survival and quality of survival were considered. In vitro studies showed that adhesive systems (3-step, etch-and-rinse) result in the best (micro)shear bond strength values compared to self-adhesive and self-etch systems when luting glass-ceramic substrates to human dentin. The highest fracture strength is obtained with adhesive cements in particular. No marked clinical preference for one specific procedure could be demonstrated on the basis of the reviewed literature. The possible merits of IDS are most convincingly illustrated by the favorable microtensile bond strengths. No clinical studies regarding IDS were found.
authors.affiliation: University Medical Center Groningen, Center for Dentistry and Oral Hygiene, Department of Fixed and Removable Prosthodontics and Biomaterials, The University of Groningen, Groningen, Netherlands.
authors.forename: Carline R G
authors.initials: CR
authors.lastname: van den Breemer
authors.affiliation: University Medical Center Groningen, Center for Dentistry and Oral Hygiene, Department of Fixed and Removable Prosthodontics and Biomaterials, The University of Groningen, Groningen, Netherlands.
authors.forename: Marco M M
authors.initials: MM
authors.lastname: Gresnigt
authors.affiliation: University Medical Center Groningen, Center for Dentistry and Oral Hygiene, Department of Fixed and Removable Prosthodontics and Biomaterials, The University of Groningen, Groningen, Netherlands ; St. Antonius Hospital Nieuwegein, Department of Oral-Maxillofacial Surgery, Prosthodontics and Special Dental Care, Nieuwegein, Netherlands.
authors.forename: Marco S
authors.initials: MS
authors.lastname: Cune
mesh_terms: D002484:Cementation; D002516:Ceramics / Q000737:chemistry*; D003738:Dental Cements / Q000737:chemistry*; D058250:Dental Restoration Repair; D003799:Dental Stress Analysis; D006801:Humans; D013718:Tensile Strength
chemical_list: D003738:Dental Cements; C023506:Glass ceramics