title: Matrix metalloproteinases and epileptogenesis.
abstract: Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
authors.affiliation: Department of Neurology, University of Wisconsin, Madison, WI, 53705, USA. ikonomidou@neurology.wisc.edu.
authors.forename: Chrysanthy
authors.initials: C
authors.lastname: Ikonomidou
keywords: Cell death; Epilepsy; Extracellular matrix; Neuroinflammation; Prevention; Synaptic plasticity