title: Development of novel magnetic solid phase extraction materials based on Fe3O4/SiO2/poly(acrylamide-N,N'-methylene bisacrylamide)-Pluronic L64 composite microspheres and their application to the enrichment of natamycin.
abstract: Novel magnetic adsorbents based on Fe3O4/SiO2/poly(acrylamide-N,N'-methylene bisacrylamide) magnetic microspheres modified with non-ionic triblock copolymer surfactant were successfully prepared as a magnetic solid phase extraction adsorbent for the determination of trace natamycin in jam samples. The adsorbent was characterized by scanning electron microscopy, transmission electron microscopy, Fourier transformed infrared spectroscopy, vibrating sample magnetometer, and X-ray diffractometer analysis, confirming that Pluronic L64 was effectively functionalized on the magnetic materials. Various experimental parameters affecting the extraction capacity were investigated including adsorbent amount, extraction time, desorption time, sample pH, and ionic strength. For recovery evaluations, the jam samples were spiked at two concentration levels of 100 and 200μgkg(-1) of natamycin and the recovery values were in the range of 78.8-93.4%. The relative standard deviations (RSD) for the recoveries were less than 3.5%. The novel magnetic solid phase extraction method provided several advantages, such as simplicity, low environmental impact, convenient extraction procedure, and short analysis time when used for natamycin analysis.
authors.affiliation: College of Chemistry, Jilin University, Changchun 130012, PR China; College of Chemistry and Chemical Engineering, Harbin Normal University, Harbin 150025, PR China.
authors.forename: Miaomiao
authors.initials: M
authors.lastname: Tian
authors.affiliation: State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, PR China.
authors.forename: Yongcun
authors.initials: Y
authors.lastname: Zou
authors.affiliation: College of Chemistry, Jilin University, Changchun 130012, PR China.
authors.forename: Shaoyan
authors.initials: S
authors.lastname: Zhou
authors.affiliation: College of Life Sciences, Jilin University, Changchun 130012, PR China.
authors.forename: Tianpeng
authors.initials: T
authors.lastname: Wang
authors.affiliation: College of Chemistry, Jilin University, Changchun 130012, PR China.
authors.forename: Xueju
authors.initials: X
authors.lastname: Lv
authors.affiliation: College of Chemistry, Jilin University, Changchun 130012, PR China. Electronic address: jiaqiong@jlu.edu.cn.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Jia
mesh_terms: D000178:Acrylamides / Q000737:chemistry*; D000180:Acrylic Resins / Q000737:chemistry*; D000891:Anti-Infective Agents, Local / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D005290:Ferric Compounds / Q000737:chemistry*; D008280:Magnetics; D008855:Microscopy, Electron, Scanning; D010866:Natamycin / Q000737:chemistry / Q000302:isolation & purification*; D020442:Poloxamer / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000379:methods*; D017550:Spectroscopy, Fourier Transform Infrared; D000099166:Polyacrylamides
chemical_list: D000178:Acrylamides; D000180:Acrylic Resins; D000891:Anti-Infective Agents, Local; D005290:Ferric Compounds; D010866:Natamycin; D020442:Poloxamer; D012822:Silicon Dioxide; D000099166:Polyacrylamides; C000499:ferric oxide; C514452:pluronic L64; C021221:N,N'-methylenebisacrylamide
keywords: Jam; Magnetic solid phase extraction; Natamycin; Non-ionic triblock copolymers