title: FRET-Based Probe for Monitoring pH Changes in Lipid-Dense Region of Hct116 Cells.
abstract: A rhodamine conjugate (L) with a pseudo Stokes shift of 165 nm is used for probing changes in solution pH under physiological conditions. This reagent is found to be nontoxic, and the luminescence response could be used for imaging changes in endogenous pH induced by dexamethanose (DMT) in the endoplasmic reticulum.
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory , Pune 411008, India.
authors.forename: Upendar
authors.initials: U
authors.lastname: Reddy G
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory , Pune 411008, India.
authors.forename: Anila H
authors.initials: AH
authors.lastname: A
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory , Pune 411008, India.
authors.forename: Firoj
authors.initials: F
authors.lastname: Ali
authors.affiliation: Chromatin and Disease Biology Laboratory, National Centre for Cell Science , Pune 411007, India.
authors.forename: Nandaraj
authors.initials: N
authors.lastname: Taye
authors.affiliation: Chromatin and Disease Biology Laboratory, National Centre for Cell Science , Pune 411007, India.
authors.forename: Samit
authors.initials: S
authors.lastname: Chattopadhyay
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory , Pune 411008, India.
authors.forename: Amitava
authors.initials: A
authors.lastname: Das
mesh_terms: D000818:Animals; D004721:Endoplasmic Reticulum / Q000187:drug effects; D005456:Fluorescent Dyes / Q000737:chemistry*; D045325:HCT116 Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008055:Lipids / Q000032:analysis*; D049449:Luminescence; D015394:Molecular Structure; D012235:Rhodamines / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D008055:Lipids; D012235:Rhodamines