title: Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report.
abstract: Nicolau syndrome is a rare drug reaction due to intramuscular injection administration that can lead to limb loss or even death. A 3.8-year-old Iranian boy received an intramuscular injection of Benzathine Penicillin. Immediately after injection the child developed lower limb pain and livedoid discolouration and was referred to our department. The patient was diagnosed to develop Nicolau syndrome and fasciotomy carried out due to compartment syndrome. Pharmacologic therapy with Heparin, Cefazolin and Methylprednisolone was initiated. On 18(th) day, he was discharged, although he was not able to move. Finally, after 6 months of care at home, physiotherapy and Electromyography (EMG) at regular intervals, the child was gradually able to move and his claudication improved.
authors.affiliation: Neurosurgeon, Department of Neurosurgery, Medicine Faculty, Ilam University of Medical Science , Ilam, IR-Iran .
authors.forename: Masoud
authors.initials: M
authors.lastname: Hatefi
authors.affiliation: Orthopaedist, Department of Orthopaedics, Medicine Faculty, Ilam University of Medical Science , Ilam, IR-Iran .
authors.forename: Nabi Ramezani
authors.initials: NR
authors.lastname: Pirabadi
authors.affiliation: Anaesthesiologist, Department of Anesthesiology, Medicine Faculty, Ilam University of Medical Science , Ilam, IR-Iran .
authors.forename: Javaher
authors.initials: J
authors.lastname: Khajavikhan
authors.affiliation: MSc of Midwifery, Department of Midwifery, Nursing & Midwifery Faculty, Ilam University of Medical Science , Ilam, IR-Iran .
authors.forename: Molouk
authors.initials: M
authors.lastname: Jaafarpour
keywords: Benzathine penicillin; Child; Compartment syndrome; Drug reaction