title: Bioinspired pH and magnetic responsive catechol-functionalized chitosan hydrogels with tunable elastic properties.
abstract: We have developed pH- and magnetic-responsive hydrogels that are stabilized by both covalent bonding and catechol/Fe(3+) ligands. The viscoelastic properties of the gels are regulated by the complexation valence and can be used to tune drug release profiles. The stable incorporation of magnetic nanoparticles further expands control over the mechanical response and drug release, in addition to providing magnetic stimuli-responsivity to the gels.
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ali.miserez@ntu.edu.sg and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Drive, Singapore 637553, Singapore.
authors.forename: Ali
authors.initials: A
authors.lastname: Ghadban
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ali.miserez@ntu.edu.sg.
authors.forename: Anansa S
authors.initials: AS
authors.lastname: Ahmed
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ali.miserez@ntu.edu.sg and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Drive, Singapore 637553, Singapore.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Ping
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ali.miserez@ntu.edu.sg and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Drive, Singapore 637553, Singapore.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Ramos
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ali.miserez@ntu.edu.sg and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Drive, Singapore 637553, Singapore.
authors.forename: Najmul
authors.initials: N
authors.lastname: Arfin
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ali.miserez@ntu.edu.sg and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Drive, Singapore 637553, Singapore.
authors.forename: Bram
authors.initials: B
authors.lastname: Cantaert
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ali.miserez@ntu.edu.sg.
authors.forename: Raju V
authors.initials: RV
authors.lastname: Ramanujan
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore. ali.miserez@ntu.edu.sg and Centre for Biomimetic Sensor Science, Nanyang Technological University, 50 Nanyang Drive, Singapore 637553, Singapore.
authors.forename: Ali
authors.initials: A
authors.lastname: Miserez
mesh_terms: D002396:Catechols / Q000737:chemistry*; D048271:Chitosan / Q000737:chemistry*; D065546:Drug Liberation; D020100:Hydrogels / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D053758:Nanoparticles / Q000737:chemistry
chemical_list: D002396:Catechols; D020100:Hydrogels; D048271:Chitosan