title: Two new abietane diterpenoid glycosides from Clinopodium chinense.
abstract: Two new abietane diterpenoid glycosides, named clinopoditerpenes B (1) and C (2), were isolated from Clinopodium chinese. The structures of the new compounds were determined on the basis of extensive spectral analysis. Compound 1 exhibited cardioprotective effect against H2O2-induced apoptosis in H9c2 cells.
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.
authors.forename: Yin-Di
authors.initials: YD
authors.lastname: Zhu
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.
authors.forename: Jing-Yi
authors.initials: JY
authors.lastname: Zhang
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Li
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.
authors.forename: Hai-Feng
authors.initials: HF
authors.lastname: Wu
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.
authors.forename: Nai-Liang
authors.initials: NL
authors.lastname: Zhu
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.|b Key Laboratory of Chinese Materia Medica, Ministry of Education , Heilongjiang University of Chinese Medicine , Harbin , People's Republic of China.
authors.forename: Hai
authors.initials: H
authors.lastname: Jiang
authors.affiliation: c Department of Nephrology , Beijing Hospital of Traditional Chinese Medicine, Capital Medical University , Beijing , People's Republic of China.
authors.forename: Cui-Yan
authors.initials: CY
authors.lastname: Lv
authors.affiliation: d Health-cultivation Laboratory of the Ministry Education , Beijing University of Chinese Medicine , Beijing , People's Republic of China.
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Wu
authors.affiliation: e The Museum of Chinese Medicine , Beijing University of Chinese Medicine , Beijing , People's Republic of China.
authors.forename: Ze-Xin
authors.initials: ZX
authors.lastname: Ma
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Xu
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.
authors.forename: Guo-Xu
authors.initials: GX
authors.lastname: Ma
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education , Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing , People's Republic of China.
authors.forename: Jun-Shan
authors.initials: JS
authors.lastname: Yang
mesh_terms: D045784:Abietanes / Q000737:chemistry / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D002316:Cardiotonic Agents / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D006801:Humans; D006861:Hydrogen Peroxide / Q000633:toxicity*; D019686:Lamiaceae / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D045784:Abietanes; D002316:Cardiotonic Agents; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D010936:Plant Extracts; C000611802:clinopoditerpene B; C000611803:clinopoditerpene C; D006861:Hydrogen Peroxide
keywords: Clinopodium chinese; cardioprotective effect; diterpenoid glycoside