title: 980-Nm Diode Laser Vaporization versus Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia: Randomized Controlled Study.
abstract: OBJECTIVE
  We compared the effectiveness and complications of 980-nm diode laser vaporization and transurethral resection of the prostate (TURP) in patients with benign prostatic hyperplasia (BPH).
  
  
  METHODS
  In total, 72 consecutive patients with BPH entered the study. All patients underwent general and urological evaluations. The primary outcome was improvement in the International Prostate Symptom Score (IPSS). The secondary outcomes were IPSS quality of life (QoL), maximum urinary flow rate (Qmax), residual volume, and complications. Patients were allocated randomly to the TURP and laser groups. The Ceralas HPD120, a diode laser system emitting at a wavelength of 980 nm, was used for photoselective vaporization of the prostate (PVP). TURP was performed with a monopolar 26 French resectoscope. Preoperative and operative parameters and surgical outcomes were compared.
  
  
  RESULTS
  In total, 36 patients in each group underwent PVP and TURP. The mean age ± standard deviation was 63.1 ± 9.1 years and 64.7 ± 10.2 years in the PVP and TURP groups, respectively. There were no statistically significant differences in age, prostate size, prostate-specific antigen concentration, Qmax, preoperative IPSS, or preoperative Qmax between the two groups. The operation duration was also similar between the groups (P = .36). The catheterization time was 1.45 ± 0.75 and 2.63 ± 0.49 days in the PVP and TURP groups, respectively (P < .01). The PVP group had a shorter hospital stay than the TURP group. The 3-month postoperative Qmax increased to 9.90 ± 3.61 and 6.59 ± 6.06 mL/s from baseline in the TURP and PVP groups, respectively; there was no difference in the increases between the groups (P = .08). The IPSS and IPSS-QoL were significantly improved with the operation (P < .01), and this improvement was similar in both groups P = .3 and P = .8, respectively . The complication rate was also similar between the two groups.
  
  
  CONCLUSIONS
  PVP with a diode laser is as safe and effective as TURP in the treatment of BPH, and the techniques have similar complication rates and functional results. PVP has the advantage of shorter hospitalization and catheter indwelling times and no need for discontinuation of anticoagulant therapy.
authors.affiliation: Department of Urology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey. drmemoly@yahoo.com.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Cetinkaya
authors.affiliation: Department of Urology, Ondokuz Mayis Medical Faculty, Ondokuz Mayis University, Samsun, Turkey.
authors.forename: Kadir
authors.initials: K
authors.lastname: Onem
authors.affiliation: Department of Urology, Medical Faculty, Mustafa Kemal University, Hatay, Turkey.
authors.forename: Mehmet Murat
authors.initials: MM
authors.lastname: Rifaioglu
authors.affiliation: Department of Urology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors.forename: Veli
authors.initials: V
authors.lastname: Yalcin
mesh_terms: D000368:Aged; D006801:Humans; D054023:Lasers, Semiconductor / Q000009:adverse effects / Q000627:therapeutic use*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000150:complications / Q000473:pathology / Q000601:surgery*; D053448:Prostatism / Q000209:etiology / Q000503:physiopathology; D011788:Quality of Life; D012720:Severity of Illness Index; D013997:Time Factors; D020728:Transurethral Resection of Prostate / Q000009:adverse effects; D016896:Treatment Outcome; D014546:Urinary Catheterization; D014563:Urodynamics