title: Pharmacology Portal: An Open Database for Clinical Pharmacologic Laboratory Services.
abstract: OBJECTIVE
  More than 50 Norwegian public and private laboratories provide one or more analyses for therapeutic drug monitoring or testing for drugs of abuse. Practices differ among laboratories, and analytical repertoires can change rapidly as new substances become available for analysis.
  
  
  METHODS
  The Pharmacology Portal was developed to provide an overview of these activities and to standardize the practices and terminology among laboratories. The Pharmacology Portal is a modern dynamic web database comprising all available analyses within therapeutic drug monitoring and testing for drugs of abuse in Norway. Content can be retrieved by using the search engine or by scrolling through substance lists. The core content is a substance registry updated by a national editorial board of experts within the field of clinical pharmacology. This ensures quality and consistency regarding substance terminologies and classification.
  
  
  RESULTS
  All laboratories publish their own repertoires in a user-friendly workflow, adding laboratory-specific details to the core information in the substance registry. The user management system ensures that laboratories are restricted from editing content in the database core or in repertoires within other laboratory subpages. The portal is for nonprofit use, and has been fully funded by the Norwegian Medical Association, the Norwegian Society of Clinical Pharmacology, and the 8 largest pharmacologic institutions in Norway.
  
  
  CONCLUSIONS
  The database server runs an open-source content management system that ensures flexibility with respect to further development projects, including the potential expansion of the Pharmacology Portal to other countries.
authors.affiliation: Laboratory of Clinical Biochemistry, Section of Clinical Pharmacology, Haukeland University Hospital, Bergen, Norway. Electronic address: tormod.karlsen.bjanes@helse-bergen.no.
authors.forename: Tormod
authors.initials: T
authors.lastname: Karlsen Bjånes
authors.affiliation: Kantega AS, Trondheim, Norway.
authors.forename: Espen
authors.initials: E
authors.lastname: Mjåset Hjertø
authors.affiliation: Kantega AS, Trondheim, Norway.
authors.forename: Lars
authors.initials: L
authors.lastname: Lønne
authors.affiliation: Clinical Pharmacology, Department of Laboratory Medicine, University Hospital of North Norway, Tromsø, Norway.
authors.forename: Lena
authors.initials: L
authors.lastname: Aronsen
authors.affiliation: Laboratory of Clinical Biochemistry, Section of Clinical Pharmacology, Haukeland University Hospital, Bergen, Norway.
authors.forename: Jon
authors.initials: J
authors.lastname: Andsnes Berg
authors.affiliation: Department of Pharmacology, Oslo University Hospital, Oslo, Norway.
authors.forename: Stein
authors.initials: S
authors.lastname: Bergan
authors.affiliation: Norwegian Institute of Public Health, Division of Forensic Medicine, Oslo, Norway.
authors.forename: Grim
authors.initials: G
authors.lastname: Otto Berg-Hansen
authors.affiliation: The Centre for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Bernard
authors.affiliation: Department of Pharmacology, Oslo University Hospital, Oslo, Norway.
authors.forename: Margrete
authors.initials: M
authors.lastname: Larsen Burns
authors.affiliation: Norwegian Institute of Public Health, Division of Forensic Medicine, Oslo, Norway.
authors.forename: Jan
authors.initials: J
authors.lastname: Toralf Fosen
authors.affiliation: Department of Clinical Pharmacology, St Olav University Hospital, Trondheim, Norway.
authors.forename: Joachim
authors.initials: J
authors.lastname: Frost
authors.affiliation: Fürst Medical Laboratory, Oslo, Norway.
authors.forename: Thor
authors.initials: T
authors.lastname: Hilberg
authors.affiliation: Department of Pharmacology, Oslo University Hospital, Oslo, Norway.
authors.forename: Hege-Merete
authors.initials: HM
authors.lastname: Krabseth
authors.affiliation: Department of Medical Biochemistry, Vestre Viken Hospital Trust, Drammen, Norway.
authors.forename: Elena
authors.initials: E
authors.lastname: Kvan
authors.affiliation: The Centre for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway.
authors.forename: Sigrid
authors.initials: S
authors.lastname: Narum
authors.affiliation: Department of Clinical Pharmacology, St Olav University Hospital, Trondheim, Norway.
authors.forename: Andreas
authors.initials: A
authors.lastname: Austgulen Westin
mesh_terms: D016208:Databases, Factual; D016903:Drug Monitoring; D006801:Humans; D020407:Internet; D007753:Laboratories; D009664:Norway; D010601:Pharmacology, Clinical; D015813:Substance Abuse Detection
keywords: Norway; analysis; clinical pharmacology; database; laboratory; standardization