title: Cytoskeletal motor-driven active self-assembly in in vitro systems.
abstract: Molecular motor-driven self-assembly has been an active area of soft matter research for the past decade. Because molecular motors transform chemical energy into mechanical work, systems which employ molecular motors to drive self-assembly processes are able to overcome kinetic and thermodynamic limits on assembly time, size, complexity, and structure. Here, we review the progress in elucidating and demonstrating the rules and capabilities of motor-driven active self-assembly. We focus on the types of structures created and the degree of control realized over these structures, and discuss the next steps necessary to achieve the full potential of this assembly mode which complements robotic manipulation and passive self-assembly.
authors.affiliation: Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, 1210 Amsterdam Avenue, MC 8904, New York, NY 10027, USA. hhess@columbia.edu.
authors.forename: A T
authors.initials: AT
authors.lastname: Lam
authors.affiliation: Sandia National Laboratories, Nanosystems Synthesis/Analysis Dept., Albuquerque, NM, USA. gdbacha@sandia.gov.
authors.forename: V
authors.initials: V
authors.lastname: VanDelinder
authors.affiliation: Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
authors.forename: A M R
authors.initials: AM
authors.lastname: Kabir
authors.affiliation: Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace, 1210 Amsterdam Avenue, MC 8904, New York, NY 10027, USA. hhess@columbia.edu.
authors.forename: H
authors.initials: H
authors.lastname: Hess
authors.affiliation: Sandia National Laboratories, Nanosystems Synthesis/Analysis Dept., Albuquerque, NM, USA. gdbacha@sandia.gov.
authors.forename: G D
authors.initials: GD
authors.lastname: Bachand
authors.affiliation: Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan and Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0810, Japan. kakugo@sci.hokudai.ac.jp.
authors.forename: A
authors.initials: A
authors.lastname: Kakugo
mesh_terms: D000818:Animals; D001692:Biological Transport; D003599:Cytoskeleton / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D020409:Molecular Motor Proteins / Q000737:chemistry / Q000378:metabolism*; D011485:Protein Binding
chemical_list: D020409:Molecular Motor Proteins