title: Oxidative stress parameters and serum magnesium levels in patients with seasonal allergic conjunctivitis.
abstract: OBJECTIVE
  To evaluate oxidative stress parameters and serum magnesium (Mg) levels in patients with seasonal allergic conjunctivitis (SAC) during the pollen season.
  
  
  METHODS
  This observational cross-sectional study involved 35 patients with SAC without any other ocular and systemic diseases, and 38 consecutive, age- and sex-matched healthy subjects. Serum malondialdehyde (MDA), adjusted ischemia modified albumin (IMA), and Mg levels were quantified, and the results were compared between the groups.
  
  
  RESULTS
  No significant differences were found between the groups with respect to age (p = 0.416) and sex (p = 0.362). Serum MDA and adjusted IMA levels of the subjects with SAC (69.54 ± 7.71 μM and 0.74 ± 0.39 ABSU) were significantly higher than the control group (64.61 ± 5.89 μM and 0.57 ± 0.19 ABSU) (p = 0.002 and p = 0.025, respectively). There was no significant difference for serum Mg levels between the groups (p = 0.177).
  
  
  CONCLUSIONS
  We demonstrated higher levels of oxidative stress parameters in patients with SAC compared to the control group, which imply a possible role of oxidative stress in the pathogenesis of SAC.
authors.affiliation: a Department of Ophthalmology , Mevlana (Rumi) University School of Medicine , Konya , Turkey and.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Dadaci
authors.affiliation: b Department of Clinical Biochemistry , Mevlana (Rumi) University School of Medicine , Konya , Turkey.
authors.forename: Mufide
authors.initials: M
authors.lastname: Oncel
authors.affiliation: a Department of Ophthalmology , Mevlana (Rumi) University School of Medicine , Konya , Turkey and.
authors.forename: Nursen
authors.initials: N
authors.lastname: Oncel Acir
authors.affiliation: b Department of Clinical Biochemistry , Mevlana (Rumi) University School of Medicine , Konya , Turkey.
authors.forename: Emel
authors.initials: E
authors.lastname: Sahin
authors.affiliation: a Department of Ophthalmology , Mevlana (Rumi) University School of Medicine , Konya , Turkey and.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Borazan
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D003233:Conjunctivitis, Allergic / Q000097:blood* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008274:Magnesium / Q000097:blood*; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D018384:Oxidative Stress; D012709:Serum Albumin; D000075462:Serum Albumin, Human; D055815:Young Adult
chemical_list: D015415:Biomarkers; D012709:Serum Albumin; C561522:ischemia-modified albumin; D008315:Malondialdehyde; D008274:Magnesium; D000075462:Serum Albumin, Human
keywords: Adjusted ischemia modified albumin; allergy; magnesium; malondialdehyde; oxidative stress; seasonal allergic conjunctivitis