title: Nanoparticle Vesicles with Controllable Surface Topographies through Block Copolymer-Mediated Self-Assembly of Silica Nanospheres.
abstract: Silica nanoparticle vesicles (NPVs) with encapsulating capability and surface permeability are highly attractive in nanocatalysis, biosensing, and drug delivery systems. Herein, we report the facile fabrication of silica NPVs composed of a monolayer of silica nanospheres (SNSs, ca. 15 nm in diameter) through the block copolymer-mediated self-assembly of SNSs. The silica NPVs gain different surface topographies, such as raspberry- and brain coral-like topographies, under controlled heat treatment conditions. The vesicular assembly of SNSs is successful with a series of poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) block copolymers, and the size of NPVs can be tuned by changing their molecular weight. The polymer is easily extracted from the NPVs with their colloidal dispersibility and structural integrity intact. The polymer-free silica NPVs further serve as a reaction vessel and host for functional materials such as tin oxide nanoparticles.
authors.affiliation: Department of Chemical System Engineering, The University of Tokyo , Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Shujun
authors.initials: S
authors.lastname: Zhou
authors.affiliation: Department of Chemical System Engineering, The University of Tokyo , Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Ayae
authors.initials: A
authors.lastname: Sugawara-Narutaki
authors.affiliation: Department of Chemical System Engineering, The University of Tokyo , Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Sachio
authors.initials: S
authors.lastname: Tsuboike
authors.affiliation: Department of Chemical System Engineering, The University of Tokyo , Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Junzheng
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Chemical System Engineering, The University of Tokyo , Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Shimojima
authors.affiliation: Department of Chemical System Engineering, The University of Tokyo , Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Okubo
mesh_terms: D016503:Drug Delivery Systems; D054118:Nanospheres / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D011095:Polyethylenes / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D011095:Polyethylenes; D011108:Polymers; D011092:Polyethylene Glycols; D012822:Silicon Dioxide