title: Termination patterns of complex partial seizures: An intracranial EEG study.
abstract: OBJECTIVE
  While seizure onset patterns have been the subject of many reports, there have been few studies of seizure termination. In this study we report the incidence of synchronous and asynchronous termination patterns of partial seizures recorded with intracranial arrays.
  
  
  METHODS
  Data were collected from patients with intractable complex partial seizures undergoing presurgical evaluations with intracranial electrodes. Patients with seizures originating from mesial temporal and neocortical regions were grouped into three groups based on patterns of seizure termination: synchronous only (So), asynchronous only (Ao), or mixed (S/A, with both synchronous and asynchronous termination patterns).
  
  
  RESULTS
  88% of the patients in the MT group had seizures with a synchronous pattern of termination exclusively (38%) or mixed (50%). 82% of the NC group had seizures with synchronous pattern of termination exclusively (52%) or mixed (30%). In the NC group, there was a significant difference of the range of seizure durations between So and Ao groups, with Ao exhibiting higher variability. Seizures with synchronous termination had low variability in both groups.
  
  
  CONCLUSIONS
  Synchronous seizure termination is a common pattern for complex partials seizures of both mesial temporal or neocortical onset. This may reflect stereotyped network behavior or dynamics at the seizure focus.
authors.affiliation: Department of Neurology, School of Medicine, University of Utah, Salt Lake City, UT, United States. Electronic address: pegah.afra@hsc.utah.edu.
authors.forename: Pegah
authors.initials: P
authors.lastname: Afra
authors.affiliation: Department of Neurology, Johns Hopkins Epilepsy Center, Johns Hopkins University School of Medicine, United States.
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Jouny
authors.affiliation: Department of Neurology, Johns Hopkins Epilepsy Center, Johns Hopkins University School of Medicine, United States.
authors.forename: Gregory K
authors.initials: GK
authors.lastname: Bergey
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000503:physiopathology* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D000069279:Drug Resistant Epilepsy / Q000503:physiopathology* / Q000601:surgery; D000069280:Electrocorticography; D004567:Electrodes, Implanted; D004828:Epilepsies, Partial / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D057234:Preoperative Period; D012640:Seizures / Q000503:physiopathology* / Q000601:surgery; D055815:Young Adult
keywords: Complex partial seizure; Intracranial EEG; Seizure dynamics; Seizure termination