title: Management of infection and febrile neutropenia in patients with solid cancer.
abstract: An expert group from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC, for its acronym in Spanish) and the Spanish Society of Medical Oncology (SEOM, for its acronym in Spanish) have reviewed the main aspects to be considered when evaluating patients with solid cancer and infectious complications contained in this article. Recommendations have, therefore, been put forth regarding the prophylaxis of the most prevalent infections in these patients, the use of vaccines, measures to control infection through vascular catheters, and preventing infection in light of certain surgical maneuvers. The following is a revision of the criteria for febrile neutropenia management and the use of colony-stimulating factors and closes with several guidelines for treating the cancer patient with serious infection. The document concludes with a series of measures to control hospital infection.
authors.affiliation: Servicio de Oncología Médica, Hospital Universitario Virgen de Macarena, Avda. Doctor Fedriani, 3, 41071, Seville, Spain. javirizuelae@seom.org.
authors.forename: J A
authors.initials: JA
authors.lastname: Virizuela
authors.affiliation: Servicio de Enfermedades Infecciosas, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Carratalà
authors.affiliation: Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Aguado
authors.affiliation: Servicio de Oncología Médica, Hospital Universitario Virgen de Macarena, Avda. Doctor Fedriani, 3, 41071, Seville, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Vicente
authors.affiliation: Unidad de Enfermedades Infecciosas, Hospital Universitari i Politècnic La Fe, Valencia, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Salavert
authors.affiliation: Servicio de Oncología Médica, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Ruiz
authors.affiliation: Unidad de Enfermedades Infecciosas, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Ruiz
authors.affiliation: Laboratori de Microbiologia, Centre de Diagnòstic Biomèdic (CDB), ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Marco
authors.affiliation: Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Lizasoain
authors.affiliation: Servicio de Oncología Médica, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Jiménez-Fonseca
authors.affiliation: Servicio de Enfermedades Infecciosas, Hospital Universitari de Bellvitge-IDIBELL, Universitat de Barcelona, Barcelona, Spain.|Institut Català d'Oncologia, Barcelona, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Gudiol
authors.affiliation: Servicio de Oncología Médica, Hospital Universitario de Guadalajara, Guadalajara, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Cassinello
authors.affiliation: Servicio de Hematología y Oncología Médica, Hospital General Universitario Morales Meseguer, Murcia, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Carmona-Bayonas
authors.affiliation: Unidad de Enfermedades Infecciosas, Hospital Universitario Virgen del Rocío, Seville, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Aguilar
authors.affiliation: Servicio de Oncología Médica, Hospital Clínico Universitario de Salamanca, Salamanca, Spain.
authors.forename: J J
authors.initials: JJ
authors.lastname: Cruz
mesh_terms: D064146:Chemotherapy-Induced Febrile Neutropenia / Q000628:therapy*; D006801:Humans; D007239:Infections / Q000150:complications* / Q000628:therapy*; D009369:Neoplasms / Q000150:complications*; D013030:Spain
keywords: Cancer; Febrile neutropenia; Infection; Prophylaxis; Risk factors