title: Comparison of functional magnetic resonance imaging in cerebral activation between normal Uygur and Mandarin participants in semantic identification task.
abstract: OBJECTIVE
  This study utilized blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI) technology to study the activated cerebral regions in normal participants whose native language was Uyghur or Chinese.
  
  
  METHODS
  We collected the fMRI data from 15 Uyghur-speaking volunteers and 15 Mandarin-speaking volunteers when executing the semantic identification task and compared the results of two groups.
  
  
  RESULTS
  Statistically significant difference of brain activation was found primarily in the left anterior cingulate gyrus (BA23) and the midline precuneus (P<0.05). When performing the semantic identification task, the Uyghur group exhibited significant activation in these two regions, whereas the Chinese group demonstrated relatively weak activation in these areas.
  
  
  CONCLUSIONS
  The cerebral regions activated by Uyghur and Chinese semantic identification are not identical, the dominant hemisphere for both languages is the left cerebral hemisphere. The left anterior cingulate gyrus might have a language function in Uyghur semantic processing.
authors.affiliation: Department of Rehabilitation Medicine, The First Affiliation Hospital of Xinjiang Medical University Urumqi 830054, China.
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: Xi
authors.affiliation: Department of Rehabilitation, Kashgar Region's First People's Hospital Kashgar 844000, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Tian
authors.affiliation: Department of Neurology, The First Affiliation Hospital of Xinjiang Medical University Urumqi 830054, China.
authors.forename: Tuerhong
authors.initials: T
authors.lastname: Tuerxun
authors.affiliation: Department of Rehabilitation Medicine, The First Affiliation Hospital of Xinjiang Medical University Urumqi 830054, China.
authors.forename: Kuerbannaimu
authors.initials: K
authors.lastname: Kaheman
authors.affiliation: Center of Image, The First Affiliation Hospital of Xinjiang Medical University Urumqi 830054, China.
authors.forename: Chun-Hui
authors.initials: CH
authors.lastname: Jiang
authors.affiliation: Department of Rehabilitation Medicine, The First Affiliation Hospital of Xinjiang Medical University Urumqi 830054, China.
authors.forename: Hai-Xia
authors.initials: HX
authors.lastname: Huang
authors.affiliation: Department of Rehabilitation Medicine, The First Affiliation Hospital of Xinjiang Medical University Urumqi 830054, China.
authors.forename: Bao-Lan
authors.initials: BL
authors.lastname: Wang
keywords: Magnetic resonance imaging; Uyghu; cerebral hemisphere; mandarin