title: Analysis of the healing process of the wounds occurring in rats using laser therapy in association with hydrocolloid.
abstract: OBJECTIVE
  To evaluate wound healing in rats by using low-level laser therapy (LLLT) associated with hydrocolloid occlusive dressing.
  
  
  METHODS
  Forty male, adult, Wistar rats were used, distributed into four groups: LG (received 2 J/cm² of laser therapy); HG (treated with hydrocolloid); LHG (treated with 2 J/cm² of laser therapy and hydrocolloid); and the CG (treated with 1 mL of 0.9% saline). The wound was evaluated at pre-determined periods 3rd and 7th days, considering the macroscopic and histological parameters (inflammatory cells, capillary neoformation, fibroblasts, collagen formation and reepithelialization).
  
  
  RESULTS
  The LG group at seven days showed increased collagen formation, the LHG group at 3 days showed mild collagen formation. The HG group and the CG at 7 days showed complete reepithelialization.
  
  
  CONCLUSIONS
  Low-level laser therapy as well as the hydrocolloid dressing have favored the wound-healing process in rats.
authors.affiliation: Hospital Universitário de Presidente Dutra, Universidade Federal do Maranhão, Sao Luis, MA, Brazil.
authors.forename: Shirley Santos
authors.initials: SS
authors.lastname: Martins
authors.affiliation: Department of Medicine II, UFMA, Sao Luis, MA, Brazil.
authors.forename: Orlando Jorge Martins
authors.initials: OJ
authors.lastname: Torres
authors.affiliation: Department of Medicine II, UFMA, Sao Luis, MA, Brazil.
authors.forename: Orlando José dos
authors.initials: OJ
authors.lastname: Santos
authors.affiliation: Department of Morphology, Universidade Federal da Paraíba, Joao Pessoa, PB, Brazil.
authors.forename: Francisco de Assis
authors.initials: Fde A
authors.lastname: Limeira Júnior
authors.affiliation: Hospital Universitário de Presidente Dutra, UFMA, Sao Luis, MA, Brazil.
authors.forename: Euler Nicolau
authors.initials: EN
authors.lastname: Sauaia Filho
authors.affiliation: Hospital Universitário de Presidente Dutra, UFMA, Sao Luis, MA, Brazil.
authors.forename: Syomara Pereira da Costa
authors.initials: SP
authors.lastname: Melo
authors.affiliation: Hospital Universitário de Presidente Dutra, UFMA, Sao Luis, MA, Brazil.
authors.forename: Rayan Haquim Pinheiro
authors.initials: RH
authors.lastname: Santos
authors.affiliation: Hospital Universitário de Presidente Dutra, UFMA, Sao Luis, MA, Brazil.
authors.forename: Vivian Brito
authors.initials: VB
authors.lastname: Silva
mesh_terms: D000818:Animals; D047070:Bandages, Hydrocolloid; D003094:Collagen / Q000032:analysis / Q000528:radiation effects; D003131:Combined Modality Therapy; D005347:Fibroblasts / Q000528:radiation effects; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D009779:Occlusive Dressings; D011897:Random Allocation; D017208:Rats, Wistar; D015203:Reproducibility of Results; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing / Q000528:radiation effects*
chemical_list: D003094:Collagen