title: Remote ischemic preconditioning enhances fracture healing.
abstract: OBJECTIVE
  We hypothesized that RIP accelerates fracture healing.
  
  
  METHODS
  Rats (n = 48) were used for the technique of ischemic preconditioning involved applying 35 min of intermittent pneumatic tourniquet for 7 cycles of 5 min each to the fractured hind limb.
  
  
  RESULTS
  We observed greater callus maturity in RIP group at first week after fracture when compared to controls (p < 0,0001). The serum MDA levels demonstrated statistically lower values at the RIP group at the first week after fracture; however, there were not significant differences at 3rd and 5th weeks (p = 0.0001, p = 0.725, p = 0.271, respectively).
  
  
  CONCLUSIONS
  Greater callus maturity was obtained in RIP group.
authors.affiliation: Departments of Orthopaedics and Traumatology, Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey.
authors.forename: Mehmet Faruk
authors.initials: MF
authors.lastname: Çatma
authors.affiliation: Departments of Orthopaedics and Traumatology, Ankara Keçiören Education and Research Hospital, Ankara, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Şeşen
authors.affiliation: Departments of Orthopaedics and Traumatology, Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey.
authors.forename: Aytekin
authors.initials: A
authors.lastname: Aydın
authors.affiliation: Departments of Orthopaedics and Traumatology, Dışkapı Yıldırım Beyazıt Education and Research Hospital, Ankara, Turkey.
authors.forename: Serhan
authors.initials: S
authors.lastname: Ünlü
authors.affiliation: Departments of Orthopaedics and Traumatology, Ankara Keçiören Education and Research Hospital, Ankara, Turkey.
authors.forename: İsmail
authors.initials: İ
authors.lastname: Demirkale
authors.affiliation: Departments of Orthopaedics and Traumatology, Ankara Keçiören Education and Research Hospital, Ankara, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Altay
keywords: Fracture; Ischemia; Malondialdehyde