title: Endovascular Therapy for Femoropopliteal Artery Disease and Association of Risk Factors With Primary Patency: The Implication of Critical Limb Ischemia and TASC II C/D Disease.
abstract: The treatment of femoropopliteal artery disease remains controversial, without clear guidelines specifying the indications for endovascular therapy (EVT). Accordingly, we retrospectively examined our experience of using EVT to treat femoropopliteal artery disease. A total of 91 limbs in 82 patients underwent EVT for the treatment of femoropopliteal artery disease. Percutaneous transluminal angioplasty alone was performed in 20 limbs, and additional stenting was performed in 71 limbs. The 1-year primary patency, primary-assisted patency, limb salvage, and survival rates were 76%, 88%, 96%, and 92%, respectively. Multivariate Cox analysis of primary patency showed that critical limb ischemia (CLI; hazard ratio [HR], 2.53; 95% confidence interval [CI], 1.08-5.33; P < .01) and TASC II C/D disease (HR, 2.70; 95% CI, 1.14-6.39; P < .05) were independent predictors of decreased primary patency. In conclusion, patients with CLI or extensive lesions have reduced patency after EVT for femoropopliteal artery disease.
authors.affiliation: Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan toshiyanishibe@yahoo.co.jp.
authors.forename: Toshiya
authors.initials: T
authors.lastname: Nishibe
authors.affiliation: Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan.
authors.forename: Kiyohito
authors.initials: K
authors.lastname: Yamamoto
authors.affiliation: Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan.
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Seike
authors.affiliation: Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ogino
authors.affiliation: Department of Surgery, Eniwa Midorino Clinic, Eniwa, Japan.
authors.forename: Masayasu
authors.initials: M
authors.lastname: Nishibe
authors.affiliation: Department of Diagnostic Radiology, Tokai University School of Medicine, Isehara, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Koizumi
authors.affiliation: Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: Alan
authors.initials: A
authors.lastname: Dardik
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical; D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000295:instrumentation / Q000401:mortality; D016638:Critical Illness; D005260:Female; D005263:Femoral Artery / Q000503:physiopathology*; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D007564:Japan; D053208:Kaplan-Meier Estimate; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011150:Popliteal Artery / Q000503:physiopathology*; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency
keywords: endovascular therapy; femoropopliteal artery; peripheral artery disease