title: [Indications and contraindications for radiosynoviorthesis].
abstract: BACKGROUND
  Radiosynoviorthesis (RSO) provides a simple method for the treatment of patients with chronic synovitis and has only few side effects.
  
  
  OBJECTIVE
  Evidence-based indications and contraindications for performing RSO based on the current literature are presented.
  
  
  METHODS
  Published information on the indications and contraindications for performing RSO in chronic synovitis were analyzed and summarized.
  
  
  RESULTS
  According to the guideline recommendations of the German Society of Rheumatology indications for RSO are given in patients with rheumatoid arthritis, seronegative spondyloarthropathy, crystal arthropathy, villonodular synovitis and hemophilia with recurrent joint bleeding. Osteoarthritis with documented reactive synovitis is also regarded as an indication in the guidelines of the nuclear medicine societies. The European League Against Rheumatism (EULAR) and the German Society of Rheumatology (DGRh) have given no recommendations for using RSO in osteoarthritis. Given the correct indications RSO shows high success rates.
  
  
  CONCLUSIONS
  The effects of RSO with the named secondary side effects last on average for 5 years. Crucial for the success of RSO are the correct indications, the correct timing and combination with other therapeutic procedures, such as surgical synovectomy.
authors.affiliation: Klinik und Poliklinik für Orthopädie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland. t.beil@klinikumbb.de.|Klinik für Orthopädie und Orthopädische Rheumatologie, Klinikum Bad Bramstedt, Universitätsklinikum Hamburg-Eppendorf, Oskar-Alexander-Str. 26, 24576, Bad Bramstedt, Deutschland. t.beil@klinikumbb.de.
authors.forename: F T
authors.initials: FT
authors.lastname: Beil
authors.affiliation: Klinik und Poliklinik für Orthopädie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.|Klinik für Orthopädie und Orthopädische Rheumatologie, Klinikum Bad Bramstedt, Universitätsklinikum Hamburg-Eppendorf, Oskar-Alexander-Str. 26, 24576, Bad Bramstedt, Deutschland.
authors.forename: W
authors.initials: W
authors.lastname: Rüther
mesh_terms: D004305:Dose-Response Relationship, Drug; D019317:Evidence-Based Medicine; D006801:Humans; D007270:Injections, Intra-Articular / Q000009:adverse effects / Q000379:methods / Q000592:standards; D038622:Internationality; D017410:Practice Guidelines as Topic; D011832:Radiation Injuries / Q000209:etiology* / Q000517:prevention & control; D011868:Radioisotopes / Q000008:administration & dosage* / Q000009:adverse effects*; D019275:Radiopharmaceuticals / Q000008:administration & dosage; D012216:Rheumatic Diseases / Q000175:diagnosis / Q000532:radiotherapy*; D012219:Rheumatology / Q000592:standards*; D016896:Treatment Outcome
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals
keywords: Indications; Joint effusion; Radionuclide; Synovectomy; Synovitis