title: New ultrasensitive resonant photonic platform for label-free biosensing.
abstract: A multi-analyte biosensing platform with ultra-high resolution ( = 0.2 ng/mL),-which is appropriate for the detection in the human serum of a wide range of biomarkers, e.g. those allowing the lung cancer early diagnosis, has been designed. The platform is based on a new configuration of planar ring resonator. The very strong light-matter interaction enabled by the micro-cavity allows a record limit-of-detection of 0.06 pg/mm(2), five times better than the state-of-the-art. The device with footprint = 2,200 μm(2) for each ring, due to its features, has the potential to be integrated in lab-on-chip microsystems for large-scale screenings of people with high risk of developing cancer.
authors.forename: Francesco
authors.initials: F
authors.lastname: Dell'Olio
authors.forename: Donato
authors.initials: D
authors.lastname: Conteduca
authors.forename: Caterina
authors.initials: C
authors.lastname: Ciminelli
authors.forename: Mario Nicola
authors.initials: MN
authors.lastname: Armenise