title: Clinical comparison of percutaneous coronary intervention with domestic drug-eluting stents versus off pump coronary artery bypass grafting in unprotected left main coronary artery disease.
abstract: OBJECTIVE
  The aim of our study was to compare the clinical outcomes of percutaneous coronary intervention (PCI) with domestic drug-eluting stents (DES) and off pump coronary artery bypass grafting (CABG) for the treatment of unprotected left main coronary artery (ULMCA) disease.
  
  
  METHODS
  A total of 227 patients with ULMCA disease and underwent revascularization was included. One hundred and six patients were treated with PCI with domestic DES implantation and 121 patients with off pump CABG. Clinical outcomes with respect to the major adverse cardiovascular and cerebrovascular events (MACCE) including death any cause, non-fatal myocardial infarction (MI), stroke, and target vessel revascularization (TVR) during hospitalization and at 12-month follow-up were recorded.
  
  
  RESULTS
  There was no significant difference between the domestic DES and off pump CABG groups in the risk of death, non-fatal MI, stroke, and TVR during hospitalization and at 12-month follow-up. Overall in-hospital MACCE in PCI versus CABG was 0.94% versus 5.78% (P<0.05). The overall MACCE at 12-month follow up in PCI versus CABG was in 3.77% versus 3.31% (P>0.05).
  
  
  CONCLUSIONS
  Domestic DES is feasible and safety in the treatment of ULMCA lesions. When compared with off-pump CABG, domestic DES achieved similar completeness of revascularization, similar in-hospital and 12-month follow-up outcomes. A longer follow-up is needed.
authors.affiliation: Department of Cardiology, Cangzhou Central Hospital Cangzhou 061001, P. R. China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Yin
authors.affiliation: Department of Cardiology, Cangzhou Central Hospital Cangzhou 061001, P. R. China.
authors.forename: Xingli
authors.initials: X
authors.lastname: Xin
authors.affiliation: Department of Cardiology, Cangzhou Central Hospital Cangzhou 061001, P. R. China.
authors.forename: Tao
authors.initials: T
authors.lastname: Geng
authors.affiliation: Department of Cardiology, Cangzhou Central Hospital Cangzhou 061001, P. R. China.
authors.forename: Zesheng
authors.initials: Z
authors.lastname: Xu
keywords: Unprotected left main coronary artery; coronary artery bypass grafting; drug-eluting stents; percutaneous coronary intervention