title: Cutaneous leishmaniasis mimicking granulomatous cheilitis and treated successfully with oral fluconazole in a boy.
abstract: Cutaneous leishmaniasis is a protozoan infectious disease and widespread in Mediterranean basin including Turkey. Lesions usually start with erythematous papules, gradually enlarges and afterwards it ulcerates. We present a 12-year-old boy with diffuse persistent lip swelling mimicking granulomatous cheilitis. Systemic glucantime was started. However, severe hypotension and bradycardia was developed after injection. Oral fluconazole was started and the lesion resolved completely. Cutaneous leishmaniasis can have varied clinical manifestations and should be suspected especially in endemic areas. Oral fluconazole seems to be safe and effective treatment modality in paediatric cases.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Mustafa Kemal University, İskenderun St., Hatay 31100, Turkey.
authors.forename: Gamze
authors.initials: G
authors.lastname: Serarslan
authors.affiliation: Department of Dermatology, Faculty of Medicine, Mustafa Kemal University, İskenderun St., Hatay 31100, Turkey.
authors.forename: Metin
authors.initials: M
authors.lastname: Aksakal
mesh_terms: D000981:Antiprotozoal Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D003937:Diagnosis, Differential; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy; D008046:Lip / Q000473:pathology; D008297:Male; D008536:Meglumine / Q000009:adverse effects / Q000627:therapeutic use*; D000077485:Meglumine Antimoniate; D008556:Melkersson-Rosenthal Syndrome / Q000175:diagnosis; D009942:Organometallic Compounds / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate; D015725:Fluconazole