title: Tinea profunda of the genital area. Successful treatment of a rare skin disease.
abstract: We present a rare case of 36-year-old female patient, who developed a severe Majocchi granuloma in the pubis after waxing, with isolated causative agent Trichophyton mentagrophytes. The condition was initially misdiagnosed as a bacterial folliculitis and treated unsuccessfully with topical corticosteroids and antibiotics. After the adequate diagnose was confirmed by mycological examination, followed by histopathological verification, complete remission of the symptoms was achieved at the 4th week after initiating 6 weeks course of antifungal therapy with Terbinafine 250 mg/daily dose, while good therapeutic response was observed even in the 10th day. The etiopathogenesis of the disease, as well as its current treatment options are considered, in respect to the rare occurrence of this condition in the pubic area and its frequent misdiagnosis.
authors.affiliation: Medical College, Medical University of Varna, 84 Tzar Osvoboditel str., Varna, 9000, Bulgaria.
authors.forename: Ilko
authors.initials: I
authors.lastname: Bakardzhiev
authors.affiliation: "Onkoderma"-Policlinic for Dermatology and Dermatologic Surgery, General Skobelev 26 blvd., Sofia, Bulgaria.
authors.forename: Anastasiya
authors.initials: A
authors.lastname: Chokoeva
authors.affiliation: Medical Faculty, Policlinic for Dermatology and Venereology, Saint Kliment Ohridski University, University Hospital Lozenetz, Koziak street 1, Sofia, 1407, Bulgaria.
authors.forename: Georgi
authors.initials: G
authors.lastname: Tchernev
authors.affiliation: Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
authors.forename: Uwe
authors.initials: U
authors.lastname: Wollina
authors.affiliation: University of Rome "G. Marconi", Rome, Italy.|Department of Biotechnology, Delft University of Technology, 2628, BC, Delft, The Netherlands.
authors.forename: Torello
authors.initials: T
authors.lastname: Lotti
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D003951:Diagnostic Errors; D005260:Female; D005499:Folliculitis / Q000175:diagnosis / Q000382:microbiology; D005831:Genital Diseases, Female / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D009281:Naphthalenes / Q000627:therapeutic use*; D011237:Predictive Value of Tests; D012074:Remission Induction; D012867:Skin / Q000187:drug effects* / Q000382:microbiology / Q000473:pathology; D000077291:Terbinafine; D013997:Time Factors; D014006:Tinea Capitis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D016896:Treatment Outcome; D014249:Trichophyton / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine
keywords: Majocchi granuloma; Trichophyton mentagrophytes; pubis; tinea genitalis profunda