title: Acute Respiratory Distress Syndrome Manifested by Leptospirosis Successfully Teated by Extracorporeal Membrane Oxygenation (ECMO).
abstract: Leptospirosis is recognized as a zoonotic disease that is emerging worldwide. Severe manifestations are associated with high morbidity and mortality rates and may therefore pose an important risk to public health, especially in certain high prevalence areas like Taiwan. The severe pulmonary form of leptospirosis is a lesser known entity and is characterized by intra-alveolar hemorrhage and can lead to acute respiratory failure with resistant hypoxemia, which leads to high mortality rates despite maximally invasive mechanical ventilation and adequate treatment. We herein present a case of severe leptospirosis complicated by massive pulmonary hemorrhage, which was successfully managed by extra corporeal membrane oxygenation.
authors.affiliation: Department of Medicine, Kaohsiung Armed Forces General Hospital, Taiwan.
authors.forename: Chen-Yi
authors.initials: CY
authors.lastname: Liao
authors.forename: Ren-Jy
authors.initials: RJ
authors.lastname: Ben
authors.forename: Hau-Ming
authors.initials: HM
authors.lastname: Wu
authors.forename: Shih-Kun
authors.initials: SK
authors.lastname: Chang
authors.forename: Mei-Yu
authors.initials: MY
authors.lastname: Liu
authors.forename: Hsien-Kuo
authors.initials: HK
authors.lastname: Chin
authors.forename: Yen-Cheng
authors.initials: YC
authors.lastname: Yeh
mesh_terms: D000328:Adult; D000818:Animals; D001803:Blood Transfusion; D015199:Extracorporeal Membrane Oxygenation; D006801:Humans; D007919:Leptospira / Q000302:isolation & purification*; D007922:Leptospirosis / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D015995:Prevalence; D012121:Respiration, Artificial / Q000009:adverse effects; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D013624:Taiwan; D016896:Treatment Outcome