title: Percutaneous Pulmonary Valve Implantation: Present Status and Evolving Future.
abstract: Due to recurrent right ventricular outflow tract (RVOT) dysfunction, patients with complex congenital heart disease of the RVOT traditionally require multiple surgical interventions during their lifetimes. Percutaneous pulmonary valve implantation (PPVI) has been developed as a nonsurgical alternative for the treatment of right ventricular to pulmonary artery stenosis or pulmonary regurgitation. PPVI has been shown to be a safe and effective procedure in patients with dysfunctional surgical RVOT conduits. In this population, PPVI has the potential to improve symptoms, functional capacity, and biventricular hemodynamics. However, limitations to the anatomical substrate and size of the RVOT currently restrict PPVI eligibility to less than one-quarter of patients with RVOT dysfunction. The current review discusses contemporary practices in PPVI, evidence supporting the procedure, and future technologies and developments in the field.
authors.affiliation: Metro Heart and Vascular Institute, Metro Health Hospital, Michigan State University, Wyoming, Michigan. Electronic address: mmansarimd@gmail.com.
authors.forename: Mohammad M
authors.initials: MM
authors.lastname: Ansari
authors.affiliation: Division of Cardiology, Department of Medicine, University of Miami Jackson Memorial Hospital, Miami, Florida.
authors.forename: Rhanderson
authors.initials: R
authors.lastname: Cardoso
authors.affiliation: Division of Cardiology, Department of Medicine, University of Miami Jackson Memorial Hospital, Miami, Florida.
authors.forename: Daniel
authors.initials: D
authors.lastname: Garcia
authors.affiliation: Division of Pediatric Cardiology, Department of Medicine, University of Miami-Jackson Memorial Hospital, Miami, Florida.
authors.forename: Satinder
authors.initials: S
authors.lastname: Sandhu
authors.affiliation: Division of Cardiology, Department of Medicine, Peter Munk Cardiac Centre, Toronto General Hospital, Toronto, Ontario, Canada.
authors.forename: Eric
authors.initials: E
authors.lastname: Horlick
authors.affiliation: Department of Cardiothoracic Surgery, Lenox Hill Heart and Vascular Institute, New York, New York.
authors.forename: Derek
authors.initials: D
authors.lastname: Brinster
authors.affiliation: Division of Cardiology, Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Martucci
authors.affiliation: Division of Cardiology, Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada.
authors.forename: Nicolo
authors.initials: N
authors.lastname: Piazza
mesh_terms: D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D011664:Pulmonary Valve / Q000601:surgery*; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000601:surgery*
keywords: congenital heart disease; outcome assessment (health care); pulmonary regurgitation; right ventricular outflow tract dysfunction; transcatheter pulmonary valve