title: Use of Lidocaine 2% Gel Does Not Reduce Pain during Flexible Cystoscopy and Is Not Cost-Effective.
abstract: OBJECTIVE
  To compare the use of lubricant gel with lidocaine versus lubricant gel without anesthetic in flexible cystoscopy in terms of pain and tolerability.
  
  
  METHODS
  In this observational non-randomized study, 72 patients were divided into two groups. Group 1 included 38 patients in whom lidocaine gel 2% was used and group 2 included 34 patients in whom lubricant gel without anesthetic was administered. The main variables analyzed were score in visual analogue scale (VAS) and score in Spanish Pain Questionnaire (SPQ). Student's t-test and Chi-square test were used to compare differences between 2 groups. The P values < .05% were considered statistically significant.
  
  
  RESULTS
  Mean age of patients in group 1 was 64.50 ± 12.39 years and 67.79 ± 10.87 years in group 2 (P = .23). The distribution according to sex was 29 men and 9 women in group 1 and 25 men and 9 women in group 2 (P = .78). The total VAS score was 2.21 ± 2.05 in group 1 versus 1.59 ± 1.61 in group 2 (P = .16). In the SPQ, the current intensity value was 1.82 ± 0.86 in group 1 versus 1.53 ± 0.74 in group 2 (P = .14), and the total intensity value was 1.92 ± 1.86 in group 1 versus 1.03 ± 1.75 in group 2 (P = .04). The cost of gel with lidocaine is 1.25 euro and gel without anesthetic 0.22 euro.
  
  
  CONCLUSIONS
  The use of lidocaine gel does not produce benefit in terms of pain relief in flexible cystoscopy and also is costly.
authors.affiliation: Department of Urology, La Inmaculada Hospital, Huercal Overa (Almeria), Spain.
authors.forename: Maria Del Carmen
authors.initials: Mdel C
authors.lastname: Cano-Garcia
authors.affiliation: Department of Urology, La Inmaculada Hospital, Huercal Overa (Almeria), Spain.
authors.forename: Rosario
authors.initials: R
authors.lastname: Casares-Perez
authors.affiliation: Department of Urology, Granada Universitary Hospital, IBS Granada, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Arrabal-Martin
authors.affiliation: Department of Urology, Poniente Hospital, El Ejido (Almería), Spain.
authors.forename: Sergio
authors.initials: S
authors.lastname: Merino-Salas
authors.affiliation: San Cecilio University Hospital. arrabalp@ono.com.
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Arrabal-Polo
mesh_terms: D000368:Aged; D000779:Anesthetics, Local / Q000191:economics / Q000627:therapeutic use*; D003362:Cost-Benefit Analysis; D003558:Cystoscopy / Q000009:adverse effects* / Q000379:methods; D004359:Drug Therapy, Combination; D005260:Female; D005782:Gels; D006801:Humans; D008012:Lidocaine / Q000191:economics / Q000627:therapeutic use*; D054327:Lubricants / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology / Q000517:prevention & control*; D010147:Pain Measurement; D016037:Single-Blind Method; D011795:Surveys and Questionnaires
chemical_list: D000779:Anesthetics, Local; D005782:Gels; D054327:Lubricants; D008012:Lidocaine