title: Predicting Lens Diameter: Ocular Biometry With High-Resolution MRI.
abstract: OBJECTIVE
  The aim of this study was to correlate different biometric dimensions of the eye as measured from ocular magnetic resonance imaging (MRI) scans to predict the lens diameter.
  
  
  METHODS
  High-resolution ocular MRI scans of 100 eyes of 100 patients were reviewed. Various anatomical variables of the eye such as the axial length, the globe diameter, and the lens dimensions were measured. Also, the distances between the ciliary sulcus and angle-to-angle were measured. A partial least square (PLS) regression model was built to analyze which variables influence the model regarding the lens dimensions.
  
  
  RESULTS
  Sixty-two eyes of 62 patients were included in the final analysis. The lens diameter ratio (horizontal to vertical) was 0.93 (SD: 0.04; 0.83-1.00). The partial least square regression showed a significant connection (P < 0.001) between the horizontal and vertical diameter. The partial least square regression model that included the globe diameter and the axis length resulted in the best prediction for the horizontal lens diameter. Similar to the horizontal lens diameter, globe diameter was the best predictor for the vertical lens diameter followed by the distance of the ciliary sulcus. White-to-white distance, distance of the ciliary sulcus, and axial eye length were found to have a high influence on the angle-to-angle distance.
  
  
  CONCLUSIONS
  The introduced models may serve as tools to predict the capsular bag biometry in a preoperative setting for cataract surgery or lens refilling procedures.
authors.affiliation: Department of Radiology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Erb-Eigner
authors.affiliation: Vienna Institute for Research in Ocular Surgery (VIROS), a Karl Landsteiner Institute, Hanusch Hospital, Vienna, Austria.
authors.forename: Nino
authors.initials: N
authors.lastname: Hirnschall
authors.affiliation: Vienna Institute for Research in Ocular Surgery (VIROS), a Karl Landsteiner Institute, Hanusch Hospital, Vienna, Austria.
authors.forename: Christoph
authors.initials: C
authors.lastname: Hackl
authors.affiliation: Department of Radiology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Schmidt
authors.affiliation: Department of Radiology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.
authors.forename: Patrick
authors.initials: P
authors.lastname: Asbach
authors.affiliation: Vienna Institute for Research in Ocular Surgery (VIROS), a Karl Landsteiner Institute, Hanusch Hospital, Vienna, Austria 3Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.
authors.forename: Oliver
authors.initials: O
authors.lastname: Findl
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D058452:Axial Length, Eye / Q000033:anatomy & histology; D001699:Biometry / Q000379:methods*; D005123:Eye / Q000033:anatomy & histology; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000033:anatomy & histology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012044:Regression Analysis