title: Intrinsic Hydrophobic Cairnlike Multilayer Films for Antibacterial Effect with Enhanced Durability.
abstract: One important aspect of nanotechnology includes thin films capable of being applied to a wide variety of surfaces. Indispensable functions of films include controlled surface energy, stability, and biocompatibility in physiological systems. In this study, we explored the ancient Asian coating material "lacquer" to enhance the physiological and mechanical stability of nanofilms. Lacquer is extracted from the lacquer tree and its main component called urushiol, which is a small molecule that can produce an extremely strong coating. Taking full advantage of layer-by-layer assembly techniques, we successfully fabricated urushiol-based thin films composed of small molecule/polymer multilayers by controlling their molecular interaction. Unique cairnlike nanostructures in this film, produced by urushiol particles, have advantages of intrinsic hydrophobicity and durability against mechanical stimuli at physiological environment. We demonstrated the stability tests as well as the antimicrobial effects of this film.
authors.affiliation: School of Chemical Engineering and Material Science, Chung-Ang University , 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.
authors.forename: Hyejoong
authors.initials: H
authors.lastname: Jeong
authors.affiliation: School of Chemical Engineering and Material Science, Chung-Ang University , 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.
authors.forename: Jiwoong
authors.initials: J
authors.lastname: Heo
authors.affiliation: School of Chemical and Biological Engineering, Seoul National University , 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.
authors.forename: Boram
authors.initials: B
authors.lastname: Son
authors.affiliation: School of Chemical Engineering and Material Science, Chung-Ang University , 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.
authors.forename: Daheui
authors.initials: D
authors.lastname: Choi
authors.affiliation: School of Chemical and Biological Engineering, Seoul National University , 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.|Advanced Institutes of Convergence Technology , 145 Gwanggyo-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do 16229, Republic of Korea.
authors.forename: Tai Hyun
authors.initials: TH
authors.lastname: Park
authors.affiliation: Department of Ophthalmology, Dongguk University Ilsan Hospital , 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 10326, Republic of Korea.
authors.forename: Minwook
authors.initials: M
authors.lastname: Chang
authors.affiliation: School of Chemical Engineering and Material Science, Chung-Ang University , 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.
authors.forename: Jinkee
authors.initials: J
authors.lastname: Hong
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003102:Colloids / Q000737:chemistry; D055119:Elastic Modulus; D006244:Hardness; D006367:HeLa Cells; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008826:Microbial Sensitivity Tests; D018625:Microscopy, Atomic Force; D011094:Polyethyleneimine / Q000737:chemistry; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013056:Spectrophotometry, Ultraviolet; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D003102:Colloids; D011094:Polyethyleneimine
keywords: antibacteria; intrinsic hydrophobicity; layer-by-layer; mechanical stability; urushiol