title: Successful laparoscopic common bile duct exploration in a patient with factor V deficiency, a case report and review of literature.
abstract: Factor V deficiency is a rare bleeding disorder. Fresh frozen plasma (FFP) is the only source of factor V because factor V concentrates is not available now. We present here a patient had concomitant gallbladder and common bile (CBD) stones with factor V deficiency. The patient is successfully treated by laparoscopic CBD exploration and cholecystectomy with perioperative fresh frozen plasma transfusion. To best of our knowledge, this is the first report of laparoscopic surgery successfully performed in a factor V deficiency patient. Our result suggest that laparoscopic surgery in a factor V deficient patient can be performed safely if normal coagulation profile is achieved after injection of FFP. Our experience in this case also indicate that the incidence of delayed bleeding after surgery is low once hemostasis is successfully obtained during operation and there is no need to continue FFP infusion beyond day 2 postoperative.
authors.affiliation: Department of Hepatobiliary, Pancreatic and Minimal Invasive Surgery, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, China.
authors.forename: Yu-Hua
authors.initials: YH
authors.lastname: Zhang
authors.affiliation: Department of Hepatobiliary, Pancreatic and Minimal Invasive Surgery, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, China.
authors.forename: De-Fei
authors.initials: DF
authors.lastname: Hong
authors.affiliation: Department of Hepatobiliary, Pancreatic and Minimal Invasive Surgery, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, China.
authors.forename: Zhi-Ming
authors.initials: ZM
authors.lastname: Hu
authors.affiliation: Department of Hepatobiliary, Pancreatic and Minimal Invasive Surgery, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, China.
authors.forename: Wei-Ding
authors.initials: WD
authors.lastname: Wu
authors.affiliation: Department of Hepatobiliary, Pancreatic and Minimal Invasive Surgery, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, China.
authors.forename: Cheng-Wu
authors.initials: CW
authors.lastname: Zhang
keywords: FFP transfusion; Laparoscopic; factor V deficiency; surgery