title: Epidemiological Aspects of Neonatal Mortality Due To Intrauterine Infection in Kazakhstan.
abstract: BACKGROUND
  In this study, we examined the epidemiological aspects of neonatal mortality due to intrauterine infections with regard to regional characteristics.
  
  
  METHODS
  Consolidated report of the Ministry of Health and Social Development of the Republic of Kazakhstan on children deceased during their first 28 days of life due to intrauterine infections (P23 - congenital pneumonia, P35-39 - infectious diseases specific to the perinatal period) in the country and its regions for 2010 - 2014 was used in this investigation. Descriptive and analytical methods of medical statistics and epidemiology were used as the main method of this 5-year (2010-2014) retrospective study.
  
  
  RESULTS
  Overall, 3,298 neonatal deaths from intrauterine infections were recorded in Kazakhstan during the period of 2010-2014, 1,925 of which were early and 1,373 were late neonatal deaths. The average annual rate of neonatal mortality rate from intrauterine infection in the country amounted to 1.73±0.23‰ (95% CI=1.27-2.19‰), whereas trends during the study period decreased (T=-15.3%). Regional characteristics of neonatal mortality were established. Different levels for cartograms of neonatal mortality from intrauterine infections were defined: low (up to 1.28‰), average (from 1.28‰ to 2.12‰) and high (by 2.12‰ and above). Neonatal mortality in the early and late periods was also analyzed.
  
  
  CONCLUSIONS
  This is the first epidemiological study of neonatal mortality from intrauterine infection, which contains a detailed space-time evaluation. The results of this investigation can be used to improve the state program to combat infant mortality.
authors.affiliation: Dept. of General Practitioner Nº 1 and Communicative Skills, West-Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan.
authors.forename: Marzya
authors.initials: M
authors.lastname: Mamyrbayeva
authors.affiliation: Central Asian Cancer Institute, Astana, Kazakhstan.
authors.forename: Nurbek
authors.initials: N
authors.lastname: Igissinov
authors.affiliation: Dept. of Infectious Diseases and Children's Infections, West-Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan.
authors.forename: Galina
authors.initials: G
authors.lastname: Zhumagaliyeva
authors.affiliation: Dept. of General Practitioner Nº 1 and Communicative Skills, West-Kazakhstan Marat Ospanov State Medical University, Aktobe, Kazakhstan.
authors.forename: Akmanat
authors.initials: A
authors.lastname: Shilmanova
keywords: Cartograms; Intrauterine infections; Kazakhstan; Neonatal mortality; Trends