title: Male Obesity.
abstract: Many cross-sectional analyses and longitudinal studies have examined the association between adiposity and pubertal development. In addition, the impact of an increased fat mass on reproduction and fertility in human obese men and in male animal models of obesity has been studied. A trend toward earlier pubertal development and maturation in both sexes has been shown, and the notion that obese boys might progress to puberty at a slower pace than their nonobese peers can no longer be substantiated. Impaired fertility markers and reduced reproductive functions have been observed in obesity. Obesity affects both pubertal development and fertility in men.
authors.affiliation: Department of Women & Child Health, Hospital for Children and Adolescents, University of Leipzig, Liebigstr. 20a, Leipzig D 04103, Germany; Leipzig University Medical Centre, LIFE, Leipzig Civilization Diseases Research Centre, LIFE Child, Centre for Paediatric Research, Leipzig, Germany. Electronic address: Wieland.kiess@medizin.uni-leipzig.de.
authors.forename: Wieland
authors.initials: W
authors.lastname: Kiess
authors.affiliation: Department of Women & Child Health, Hospital for Children and Adolescents, University of Leipzig, Liebigstr. 20a, Leipzig D 04103, Germany; Leipzig University Medical Centre, LIFE, Leipzig Civilization Diseases Research Centre, LIFE Child, Centre for Paediatric Research, Leipzig, Germany; IFB Adiposity Diseases, University of Leipzig, Liebigstr. 20a, Leipzig D 04103, Germany.
authors.forename: Isabel V
authors.initials: IV
authors.lastname: Wagner
authors.affiliation: Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Paul-List-Street 13-15, Leipzig 04103, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Kratzsch
authors.affiliation: Department of Women & Child Health, Hospital for Children and Adolescents, University of Leipzig, Liebigstr. 20a, Leipzig D 04103, Germany; Leipzig University Medical Centre, LIFE, Leipzig Civilization Diseases Research Centre, LIFE Child, Centre for Paediatric Research, Leipzig, Germany; IFB Adiposity Diseases, University of Leipzig, Liebigstr. 20a, Leipzig D 04103, Germany.
authors.forename: Antje
authors.initials: A
authors.lastname: Körner
mesh_terms: D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D008297:Male; D009765:Obesity / Q000150:complications*
keywords: Adipocytokines; Male fertility; Male puberty; Obesity; Reproduction; Testis