title: Pseudorabies in farmed foxes fed pig offal in Shandong province, China.
abstract: Pseudorabies (PR, Aujeszky's disease) is an acute, highly contagious viral disease resulting in major economic losses to the swine industry. PR is endemic in wild and domestic animals, although its natural host is the pig. Here, we report an outbreak of PR in foxes on a fur-producing farm in Yuncheng county, Shandong, China, that were fed pig offal. The diagnosis of PR was based on nervous signs and standard PCR methods and by isolation of PRV from fox brain tissue in Vero cells. The diagnosis was confirmed by an indirect immunofluorescence assay and electron microscopy. Phylogenetic analysis of a partial (804 nt) viral glycoprotein gC gene sequence indicated that it was likely to be a field strain closely related to a cluster of PRV previously identified in China.
authors.affiliation: Laboratory of Epidemiology, Military Veterinary Research Institute, Academy of Military Medical Sciences, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, 666 Liuying West Road, Changchun, 130122, China.
authors.forename: Hong-Liang
authors.initials: HL
authors.lastname: Jin
authors.affiliation: Laboratory of Epidemiology, Military Veterinary Research Institute, Academy of Military Medical Sciences, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, 666 Liuying West Road, Changchun, 130122, China.
authors.forename: Shu-Man
authors.initials: SM
authors.lastname: Gao
authors.affiliation: Laboratory of Epidemiology, Military Veterinary Research Institute, Academy of Military Medical Sciences, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, 666 Liuying West Road, Changchun, 130122, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Laboratory of Epidemiology, Military Veterinary Research Institute, Academy of Military Medical Sciences, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, 666 Liuying West Road, Changchun, 130122, China.
authors.forename: Shou-Feng
authors.initials: SF
authors.lastname: Zhang
authors.affiliation: Laboratory of Epidemiology, Military Veterinary Research Institute, Academy of Military Medical Sciences, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, 666 Liuying West Road, Changchun, 130122, China. ronglianghu@hotmail.com.
authors.forename: Rong-Liang
authors.initials: RL
authors.lastname: Hu
mesh_terms: D000821:Animal Feed; D000818:Animals; D001482:Base Composition; D002681:China / Q000453:epidemiology; D002522:Chlorocebus aethiops; D016000:Cluster Analysis; D004196:Disease Outbreaks; D005589:Foxes / Q000821:virology*; D011558:Herpesvirus 1, Suid / Q000235:genetics / Q000302:isolation & purification / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011557:Pseudorabies / Q000453:epidemiology* / Q000473:pathology / Q000821:virology; D017422:Sequence Analysis, DNA; D013552:Swine; D014709:Vero Cells; D014759:Viral Envelope Proteins / Q000235:genetics; D014776:Virus Cultivation
chemical_list: D014759:Viral Envelope Proteins