title: Giant pediatric glioblastoma multiforme causing primary calvarial erosion and sutural diastasis presenting with enlarged head.
abstract: Authors report a rare case of supratentorial glioblastoma multiforme in a 13-year-old boy, who had headache, vomiting and left sided hemiparesis for last 6 months. On evaluation by primary physician he was labeled as hydrocephalus in view of enlarged head with papilledema on fundoscopic evaluation and no imaging was carried out. On current admission, magnetic resonance imaging brain revealed a large heterogeneous mass lesion involving right frontoparietal region associated with massive perilesional edema causing significant mass effect. He underwent right fronto-temporal craniotomy and intraoperatively erosion of parietal bone was observed, unassociated with any extradural deposit of tumor. After surgery, he noticed improvement in headache along with hemiparesis. Primary calvarial erosion in glioblastoma is extremely rare, and there is paucity of literature as evident from the few case reports reported previously and all occurred in elderly, so current case is the first pediatric case having primary calvarial erosion. Management of such case and pertinent literature is briefly discussed.
authors.affiliation: Department of Neurosurgery, Neurosciences Centre, AIIMS, New Delhi, India.
authors.forename: Guru Dutta
authors.initials: GD
authors.lastname: Satyarthee
authors.affiliation: Department of Neurosurgery, AIIMS, Bhubaneshwar, Odisha, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Mahapatra
keywords: Calvarial destruction; enlarged skull; pediatric glioblastoma multiforme; sutural diastasis