title: [On-site fine-needle aspiration cytology of thyroid nodules. Quality assurance of the Bethesda System for Reporting Thyroid Cytopathology (2008)].
abstract: BACKGROUND
  The methods available for the diagnosis of thyroid nodules include physical examination, imaging, laboratory and fine-needle aspiration cytology tests.
  
  
  OBJECTIVE
  The aim of this study was to determine the quality assurance of fine-needle aspiration cytology of thyroid nodules.
  
  
  METHODS
  Cytology results were rated to 6 categories according to the Bethesda System for Reporting Thyroid Cytopathology (2008) (I. nondiagnostic; II. benign; III. atypia of undetermined significance; IV. follicular neoplasia; V. suspicious for malignancy; VI. malignant). All cytology reports were compared with the final histology diagnosis.
  
  
  RESULTS
  A total of 1384 patient with thyroid nodule underwent fine-needle aspiration biopsy cytology. Smears were classified I. inadequate in 214 (15.9%); II. benign 986; III. atypical 56; IV. follicular neoplasm 41; V. suspicious for malignancy 18; VI. malignant 33 cases. Two hundred and twenty seven (16.8%) of the cases were operated and histologically verified. The positive predictive value in the benign category was 98.25% and in the malignant 88.46%. The sensitivity of the follicular neoplasm was 66.67%.
  
  
  CONCLUSIONS
  The results suggest that fine-needle aspiration cytology of thyroid nodules using the Bethesda System for Reporting Thyroid Cytopathology has a high diagnostic accuracy. The auditing values of the results meet the proposed threshold values.
authors.affiliation: Országos Onkológiai Intézet Budapest, Ráth Gy. u. 7-9., 1122.
authors.forename: Mihály
authors.initials: M
authors.lastname: Bak
authors.affiliation: Országos Onkológiai Intézet Budapest, Ráth Gy. u. 7-9., 1122.
authors.forename: Ilona
authors.initials: I
authors.lastname: Péter
authors.affiliation: Fizikai és Orvosi Informatikai Intézet, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.
authors.forename: Tibor
authors.initials: T
authors.lastname: Nyári
authors.affiliation: Országos Onkológiai Intézet Budapest, Ráth Gy. u. 7-9., 1122.
authors.forename: Péter
authors.initials: P
authors.lastname: Simon
authors.affiliation: Országos Onkológiai Intézet Budapest, Ráth Gy. u. 7-9., 1122.
authors.forename: Mátyás
authors.initials: M
authors.lastname: Újlaky
authors.affiliation: Országos Onkológiai Intézet Budapest, Ráth Gy. u. 7-9., 1122.
authors.forename: András
authors.initials: A
authors.lastname: Boér
authors.affiliation: Országos Onkológiai Intézet Budapest, Ráth Gy. u. 7-9., 1122.
authors.forename: Miklós
authors.initials: M
authors.lastname: Kásler
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle / Q000592:standards; D002277:Carcinoma / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008499:Medical Records / Q000592:standards*; D008875:Middle Aged; D010338:Pathology, Clinical / Q000592:standards; D000067716:Point-of-Care Testing / Q000592:standards; D011237:Predictive Value of Tests; D011785:Quality Assurance, Health Care; D012680:Sensitivity and Specificity; D013961:Thyroid Gland / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000175:diagnosis; D016606:Thyroid Nodule / Q000175:diagnosis* / Q000473:pathology
keywords: Bethesda System for Reporting Thyroid Cytopathology (2008); citohisztológiai korreláció; cytologic-histologic correlation; fine-needle aspiration cytology; minőségbiztosítás; pajzsmirigygöb; quality assurance; thyroid nodule; vékonytű-aspirációs citológia