title: Metastatic cardiac tumor from urothelial carcinoma detected by transthoracic echocardiography: a case report.
abstract: BACKGROUND
  Cardiac metastasis of urothelial carcinoma is a very rare but clinically important complication. Most cardiac metastases are asymptomatic; symptoms from cardiac metastasis were seen in advanced stage and many of these cases were reported to have a poor prognosis. So it is important to find asymptomatic cardiac metastasis and to start chemotherapy early in order to improve the patient's prognosis.
  
  
  METHODS
  A 73-year-old Asian man was referred to our hospital because of a right ventricular tumor. He had a history of left ureteral cancer 9 years ago. In screening echocardiography for paroxysmal atrial fibrillation, a low echogenic tumor was detected in his right ventricular apex, and characteristic ST segment elevation was detected in electrocardiography. An (18)F-fluorodeoxyglucose positron emission tomography revealed abnormal uptake in his right ventricular apex tumor and prostate, and a biopsy of the prostatic tumor showed urothelial carcinoma cells. He received systemic gemcitabine, paclitaxel and cisplatin chemotherapy for the urothelial carcinoma, and the cardiac tumor size was reduced temporarily. Finally, he died of multiple organ failure 16 months after his first admission, but his survival period was relatively longer than previous reports.
  
  
  CONCLUSIONS
  We experienced a case of a metastatic cardiac tumor from urothelial carcinoma. We found asymptomatic cardiac metastasis by screening echocardiography and electrocardiography. Our patient received systemic chemotherapy and his survival period was relatively longer than previous reports. Electrocardiography and echocardiography may be useful to find asymptomatic cardiac metastasis of neoplasms.
authors.affiliation: Department of Cardiology, Neurology and Aging Science, Kochi Medical School, Kochi University, Oko-cho, Nankoku-city, Kochi, 783-8505, Japan. nakashimayasuteru@yahoo.co.jp.
authors.forename: Yasuteru
authors.initials: Y
authors.lastname: Nakashima
authors.affiliation: Department of Cardiology, Neurology and Aging Science, Kochi Medical School, Kochi University, Oko-cho, Nankoku-city, Kochi, 783-8505, Japan.
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Tanioka
authors.affiliation: Department of Cardiology, Neurology and Aging Science, Kochi Medical School, Kochi University, Oko-cho, Nankoku-city, Kochi, 783-8505, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Kubo
authors.affiliation: Department of Cardiology, Neurology and Aging Science, Kochi Medical School, Kochi University, Oko-cho, Nankoku-city, Kochi, 783-8505, Japan.
authors.forename: Naohito
authors.initials: N
authors.lastname: Yamasaki
authors.affiliation: Department of Urology, Kochi Medical School, Kochi University, Oko-cho, Nankoku-city, Kochi, 783-8505, Japan.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Yamasaki
authors.affiliation: Department of Urology, Kochi Medical School, Kochi University, Oko-cho, Nankoku-city, Kochi, 783-8505, Japan.
authors.forename: Taro
authors.initials: T
authors.lastname: Syuin
authors.affiliation: Department of Cardiology, Neurology and Aging Science, Kochi Medical School, Kochi University, Oko-cho, Nankoku-city, Kochi, 783-8505, Japan. kitaokah@kochi-u.ac.jp.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kitaoka
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D004452:Echocardiography; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D009102:Multiple Organ Failure; D017239:Paclitaxel / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D019459:Urothelium / Q000473:pathology*; D000093542:Gemcitabine
chemical_list: D003841:Deoxycytidine; D017239:Paclitaxel; D000093542:Gemcitabine