title: [Preliminary results from the French study on prenatal repair for fetal myelomeningoceles (the PRIUM study)].
abstract: OBJECTIVE
  To present the preliminary results of the PRIUM study, a French pilot study of prenatal repair for myelomeningoceles (MMC).
  
  
  METHODS
  The fetal surgery for MMC is offered in cases of patients that did not opt for termination of pregnancy.
  
  
  RESULTS
  Thirty-six patients were referred in an 18-month period. Eight patients were not eligible for prenatal repair. Another type of dysraphism was made in 6 cases (one spina-lipoma, 5 cases of limited dorsal myeloschisis). Twenty-two patients were eligible to fetal surgery. A prenatal repair was performed in three cases (14%). Four patients opted for a conventional postnatal treatment. Fifteen patients opted for termination of the pregnancy.
  
  
  CONCLUSIONS
  The establishment of a prenatal repair of MMC protocol in France was justified. The experience of the first 18months of this study however suggests that only a limited number of couples will choose this procedure after specialized counseling in a reference center.
authors.affiliation: Service de médecine fœtale, centre pluridisciplinaire de l'Est Parisien, hôpital Armand-Trousseau, AP-HP, Paris 6, 26, avenue Arnold-Netter, 75012 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Friszer
authors.affiliation: Service de médecine fœtale, centre pluridisciplinaire de l'Est Parisien, hôpital Armand-Trousseau, AP-HP, Paris 6, 26, avenue Arnold-Netter, 75012 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Dhombres
authors.affiliation: Service de neurochirurgie pédiatrique, hôpital Necker-Enfants-Malades, AP-HP, Paris 5, 49, rue de Sèvres, 75015 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Di Rocco
authors.affiliation: Département d'anesthésie, hôpital Armand-Trousseau, AP-HP, Paris 6, 26, avenue Arnold-Netter, 75012 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Rigouzzo
authors.affiliation: Service de radiopédiatrie, hôpital Armand-Trousseau, AP-HP, Paris 6, 26, avenue Arnold-Netter, 75012 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Garel
authors.affiliation: Service de médecine fœtale, centre pluridisciplinaire de l'Est Parisien, hôpital Armand-Trousseau, AP-HP, Paris 6, 26, avenue Arnold-Netter, 75012 Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Guilbaud
authors.affiliation: Unité pédiatrique de médecine physique et de réadaptation, hôpital Armand-Trousseau, AP-HP, Paris 6, 26, avenue Arnold-Netter, 75012 Paris, France.
authors.forename: V
authors.initials: V
authors.lastname: Forin
authors.affiliation: Service de neuropédiatrie, hôpital Armand-Trousseau, AP-HP, Paris 6, 26, avenue Arnold-Netter, 75012 Paris, France.
authors.forename: M-L
authors.initials: ML
authors.lastname: Moutard
authors.affiliation: Service de neurochirurgie pédiatrique, hôpital Necker-Enfants-Malades, AP-HP, Paris 5, 49, rue de Sèvres, 75015 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Zerah
authors.affiliation: Service de médecine fœtale, centre pluridisciplinaire de l'Est Parisien, hôpital Armand-Trousseau, AP-HP, Paris 6, 26, avenue Arnold-Netter, 75012 Paris, France. Electronic address: jean-marie.jouannic@trs.aphp.fr.
authors.forename: J-M
authors.initials: JM
authors.lastname: Jouannic
mesh_terms: D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000601:surgery*; D046128:Fetal Therapies / Q000379:methods* / Q000592:standards; D005602:France; D006801:Humans; D008591:Meningomyelocele / Q000601:surgery*; D010865:Pilot Projects; D011247:Pregnancy; D055815:Young Adult
keywords: Chirurgie fœtale; Diagnostic prénatal; Fetal surgery; Myelomeningocele; Myéloméningocèle; Prenatal diagnosis