title: HemaSpot, a Novel Blood Storage Device for HIV-1 Drug Resistance Testing.
abstract: HemaSpot, a novel dried-blood storage filter device, was used for HIV-1 pol resistance testing in 30 fresh United States blood samples and 54 previously frozen Kenyan blood samples. Genotyping succeeded in 79% and 58% of samples, respectively, improved with shorter storage and higher viral load, and had good (86%) resistance mutation concordance to plasma.
authors.affiliation: Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
authors.forename: K
authors.initials: K
authors.lastname: Brooks
authors.affiliation: Center for Statistical Sciences, School of Public Health, Brown University, Providence, Rhode Island, USA.
authors.forename: A
authors.initials: A
authors.lastname: DeLong
authors.affiliation: Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
authors.forename: M
authors.initials: M
authors.lastname: Balamane
authors.affiliation: Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
authors.forename: L
authors.initials: L
authors.lastname: Schreier
authors.affiliation: Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
authors.forename: M
authors.initials: M
authors.lastname: Orido
authors.affiliation: Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
authors.forename: M
authors.initials: M
authors.lastname: Chepkenja
authors.affiliation: Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
authors.forename: E
authors.initials: E
authors.lastname: Kemboi
authors.affiliation: Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
authors.forename: M
authors.initials: M
authors.lastname: D'Antuono
authors.affiliation: Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Chan
authors.affiliation: Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya Department of Medicine, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
authors.forename: W
authors.initials: W
authors.lastname: Emonyi
authors.affiliation: Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya Department of Medicine, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya.
authors.forename: L
authors.initials: L
authors.lastname: Diero
authors.affiliation: Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA.
authors.forename: M
authors.initials: M
authors.lastname: Coetzer
authors.affiliation: Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA rkantor@brown.edu.
authors.forename: R
authors.initials: R
authors.lastname: Kantor
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001769:Blood / Q000821:virology*; D001793:Blood Preservation; D003890:Desiccation; D004864:Equipment and Supplies; D005260:Female; D060005:Genotyping Techniques / Q000379:methods*; D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000187:drug effects*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods*; D008875:Middle Aged; D013048:Specimen Handling / Q000295:instrumentation* / Q000379:methods; D014481:United States; D055815:Young Adult