title: Multicentric Primary Angiosarcoma of Bone Mimicking Metastasis on (18)F-FDG PET/CT in a Patient with a History of Sigmoid Colon Cancer: a Case Report.
abstract: Primary angiosarcoma of the bone (PAB) is a rare and fatal high-grade malignant vascular bone tumor. We report a rare case of multicentric PAB mimicking bone metastasis in a 59-year-old female patient with a history of sigmoid colon cancer. This patient complained of lower back and pelvic pain and presented with multiple osteolytic bone lesions on plain radiography and pelvic computed tomography. First, bone metastasis of sigmoid colon cancer was suspected. However, on the (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) scan, the patient presented unusual multiple hypermetabolic osteolytic bone lesions involving contiguous bones of the lower half of the body. After bone biopsy, these lesions were confirmed to be multicentric PAB. To the best of our knowledge, this is the first case report of an (18)F-FDG PET/CT scan in a patient with multicentric primary bone angiosarcoma.
authors.affiliation: Department of Nuclear Medicine, National Cancer Center, Goyang-si, Gyeonggi-go Korea ; Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Min Young
authors.initials: MY
authors.lastname: Yoo
authors.affiliation: Department of Nuclear Medicine, Chung-Ang University Hospital, Seoul, Korea.
authors.forename: Eun Seong
authors.initials: ES
authors.lastname: Lee
authors.affiliation: Department of Nuclear Medicine, National Cancer Center, Goyang-si, Gyeonggi-go Korea.
authors.forename: Seok-Ki
authors.initials: SK
authors.lastname: Kim
authors.affiliation: Department of Pathology, National Cancer Center, Goyang-si, Gyeonggi-do Korea.
authors.forename: Seog-Yun
authors.initials: SY
authors.lastname: Park
authors.affiliation: Department of Pathology, National Cancer Center, Goyang-si, Gyeonggi-do Korea.
authors.forename: Youngmee
authors.initials: Y
authors.lastname: Kwon
authors.affiliation: Hematologic Oncology Clinic, Center for Specific Organs Cancer, National Cancer Center, Research Institute and Hospital, Goyang, Gyeonggi-do Korea.
authors.forename: Tak
authors.initials: T
authors.lastname: Yun
authors.affiliation: Department of Nuclear Medicine, National Cancer Center, Goyang-si, Gyeonggi-go Korea.
authors.forename: Tae Sung
authors.initials: TS
authors.lastname: Kim
keywords: 18F-FDG positron-emission tomography; Bone; Primary angiosarcoma