title: Novel CT and scintigraphic findings of bone metastasis from invasive lobular breast cancer.
abstract: BACKGROUND
  The aim of this study is to identify and describe the computed tomography and scintigraphic imaging patterns of osseous metastasis from invasive lobular breast cancer (ILC).
  
  
  METHODS
  CT and skeletal scintigraphy (SS) studies of 23 patients with diagnosis of ILC and osseous metastasis on their initial presentation were reviewed.
  
  
  RESULTS
  Osseous metastases in 14 patients (60.8%) appear as uniform small sclerotic lesions (USSL) on CT scan. The SS in these patients were interpreted as negative for metastasis (either normal or with some equivocal findings not typical for metastasis).
  
  
  CONCLUSIONS
  Osseous metastasis from ILC can have a characteristic imaging pattern on CT and SS. The pattern of USSL on CT scan with negative SS is highly suggestive of osseous metastasis from ILC.
authors.affiliation: Molecular Imaging and Therapy Service, Fiona Stanley Hospital, Perth, Western Australia, Australia.|Molecular Imaging and Therapy Service, Royal Perth Hospital, Perth, Western Australia, Australia.
authors.forename: Zeyad
authors.initials: Z
authors.lastname: Al-Ogaili
authors.affiliation: Molecular Imaging and Therapy Service, Fiona Stanley Hospital, Perth, Western Australia, Australia.|Molecular Imaging and Therapy Service, Royal Perth Hospital, Perth, Western Australia, Australia.
authors.forename: Russell
authors.initials: R
authors.lastname: Troedson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging* / Q000556:secondary*; D005260:Female; D006801:Humans; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: body CT; breast imaging; musculoskeletal; nuclear medicine; oncologic imaging