title: Dual selective iron chelating probes with a potential to monitor mitochondrial labile iron pools.
abstract: Mitochondria-targeted peptides incorporating dual fluorescent and selective iron chelators have been designed as novel biosensors for the mitochondrial labile iron pool. The probes were demonstrated to specifically co-localize with mitochondria and their fluorescence emission was found to be sensitive to the presence of iron.
authors.affiliation: Institute of Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK. robert.hider@kcl.ac.uk.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Abbate
authors.affiliation: Department of Pharmacy & Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK.
authors.forename: Olivier
authors.initials: O
authors.lastname: Reelfs
authors.affiliation: Institute of Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK. robert.hider@kcl.ac.uk.
authors.forename: Xiaole
authors.initials: X
authors.lastname: Kong
authors.affiliation: Department of Pharmacy & Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK.
authors.forename: Charareh
authors.initials: C
authors.lastname: Pourzand
authors.affiliation: Institute of Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UK. robert.hider@kcl.ac.uk.
authors.forename: Robert C
authors.initials: RC
authors.lastname: Hider