title: Therapeutic management of cerebral arteriovenous malformations: a review.
abstract: The therapeutic management of cerebral arteriovenous malformations has undergone significant change over the past 40 years. Embolization, radiosurgery, advanced imaging modalities, neuropsychological testing and advances in surgical technique has both significantly improved our ability to treat patients, as well as confounding the landscape as to what constitutes best medical practice. Variability in natural history provides additional challenges in that it is challenging to determine an accurate estimate of the risk of hemorrhage, morbidity and mortality. It is clear that the complexity of the treatment of these lesions demands a multidisciplinary approach. The need for a team of neurosurgeons, interventional and diagnostic neuroradiologists, neurologists, radiation oncologists and neuropsychologists will improve outcomes and aid in determining best therapy for patients.
authors.affiliation: a Weill Cornell Medical Center - Neurosurgery , 525 East 68th Street Starr Pavilion, 10065 , NY , USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Crimmins
authors.affiliation: a Weill Cornell Medical Center - Neurosurgery , 525 East 68th Street Starr Pavilion, 10065 , NY , USA.
authors.forename: Y Pierre
authors.initials: YP
authors.lastname: Gobin
authors.affiliation: a Weill Cornell Medical Center - Neurosurgery , 525 East 68th Street Starr Pavilion, 10065 , NY , USA.
authors.forename: Athos
authors.initials: A
authors.lastname: Patsalides
authors.affiliation: a Weill Cornell Medical Center - Neurosurgery , 525 East 68th Street Starr Pavilion, 10065 , NY , USA.
authors.forename: Jared
authors.initials: J
authors.lastname: Knopman
mesh_terms: D004621:Embolization, Therapeutic; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000628:therapy*; D010348:Patient Care Team; D016634:Radiosurgery; D012306:Risk
keywords: ARUBA trial; Spetzler-Martin grade; arteriovenous malformation; arteriovenous malformations treatment; embolization; radiosurgery