title: [Results of complex treatment of patients with squamous cell carcinoma of the anal canal using advanced radiotherapy technologies].
abstract: During recent decades radiotherapy is the basis, on which it is built a medical complex that is the first-line treatment of patients with squamous cell carcinoma of the anal canal. An increase of overall and disease-free survival and quality of life of patients with squamous cell carcinoma of the anal canal at the present stage of development of a comprehensive medical treatment is largely due to the improvement of technical equipment of radiotherapy departments of oncology clinics. The use of modem linear electron accelerators and systems of computer dosimetric planning to create a 3D program of isodose distribution, diagnostic devices (computed tomography and magnetic resonance imaging) as well as a number of other conditions permit accurate summarizing of proposed dose, reducing of absorbed dose to critical structures, diminishing unplanned interruptions in chemoradiotherapy course by means of modern technologies of conformal radiotherapy (3D CRT, IMRT, VMAT). The paper presents the preliminary results of a comprehensive medical treatment of 14 patients with squamous cell carcinoma of the anal canal.
authors.forename: V V
authors.initials: VV
authors.lastname: Glebovskaya
authors.forename: S I
authors.initials: SI
authors.lastname: Tkachev
authors.forename: A O
authors.initials: AO
authors.lastname: Rasulov
authors.forename: V F
authors.initials: VF
authors.lastname: Tsaryuk
authors.forename: S S
authors.initials: SS
authors.lastname: Gordeev
authors.forename: M Yu
authors.initials: MY
authors.lastname: Fedyanin
authors.forename: V A
authors.initials: VA
authors.lastname: Aliev
authors.forename: Z Z
authors.initials: ZZ
authors.lastname: Mamedly
authors.forename: D V
authors.initials: DV
authors.lastname: Kuzmichev
authors.forename: O P
authors.initials: OP
authors.lastname: Trofimova
authors.forename: T N
authors.initials: TN
authors.lastname: Borisova
authors.forename: I P
authors.initials: IP
authors.lastname: Yazhgunovich
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001005:Anus Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy*; D059248:Chemoradiotherapy; D018572:Disease-Free Survival; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D016685:Mitomycin / Q000008:administration & dosage; D010315:Particle Accelerators; D011788:Quality of Life; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D020266:Radiotherapy, Conformal / Q000295:instrumentation / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D016685:Mitomycin; D005472:Fluorouracil