title: Biosorption and degradation of decabromodiphenyl ether by Brevibacillus brevis and the influence of decabromodiphenyl ether on cellular metabolic responses.
abstract: There is global concern about the effects of decabromodiphenyl ether (BDE209) on environmental and public health. The molecular properties, biosorption, degradation, accumulation, and cellular metabolic effects of BDE209 were investigated in this study to identify the mechanisms involved in the aerobic biodegradation of BDE209. BDE209 is initially absorbed by wall teichoic acid and N-acetylglucosamine side chains in peptidoglycan, and then, BDE209 is transported and debrominated through three pathways, giving tri-, hepta-, octa-, and nona-bromodiphenyl ethers. The C-C bond energies decrease as the number of bromine atoms on the diphenyl decreases. Polybrominated diphenyl ethers (PBDEs) inhibit protein expression or accelerate protein degradation and increase membrane permeability and the release of Cl(-), Na(+), NH4 (+), arabinose, proteins, acetic acid, and oxalic acid. However, PBDEs increase the amounts of K(+), Mg(2+), PO4 (3-), SO4 (2-), and NO3 (-) assimilated. The biosorption, degradation, accumulation, and removal efficiencies when Brevibacillus brevis (1 g L(-1)) was exposed to BDE209 (0.5 mg L(-1)) for 7 days were 7.4, 69.5, 16.3, and 94.6 %, respectively.
authors.affiliation: Research Center of Environmental Pollution Control and Remediation of Guangdong Province, Key Laboratory of Environmental Exposure and Health of Guangzhou City, School of Environment, Jinan University, Guangzhou, Guangdong, 510632, China.
authors.forename: Linlin
authors.initials: L
authors.lastname: Wang
authors.affiliation: Research Center of Environmental Pollution Control and Remediation of Guangdong Province, Key Laboratory of Environmental Exposure and Health of Guangzhou City, School of Environment, Jinan University, Guangzhou, Guangdong, 510632, China.
authors.forename: Litao
authors.initials: L
authors.lastname: Tang
authors.affiliation: Research Center of Environmental Pollution Control and Remediation of Guangdong Province, Key Laboratory of Environmental Exposure and Health of Guangzhou City, School of Environment, Jinan University, Guangzhou, Guangdong, 510632, China.
authors.forename: Ran
authors.initials: R
authors.lastname: Wang
authors.affiliation: Research Center of Environmental Pollution Control and Remediation of Guangdong Province, Key Laboratory of Environmental Exposure and Health of Guangzhou City, School of Environment, Jinan University, Guangzhou, Guangdong, 510632, China.
authors.forename: Xiaoya
authors.initials: X
authors.lastname: Wang
authors.affiliation: Research Center of Environmental Pollution Control and Remediation of Guangdong Province, Key Laboratory of Environmental Exposure and Health of Guangzhou City, School of Environment, Jinan University, Guangzhou, Guangdong, 510632, China. jsye@jnu.edu.cn.
authors.forename: Jinshao
authors.initials: J
authors.lastname: Ye
authors.affiliation: Research Center of Environmental Pollution Control and Remediation of Guangdong Province, Key Laboratory of Environmental Exposure and Health of Guangzhou City, School of Environment, Jinan University, Guangzhou, Guangdong, 510632, China. dragonflamely@163.com.
authors.forename: Yan
authors.initials: Y
authors.lastname: Long
mesh_terms: D001673:Biodegradation, Environmental; D058675:Brevibacillus / Q000378:metabolism*; D001966:Bromine / Q000737:chemistry; D055768:Halogenated Diphenyl Ethers / Q000737:chemistry / Q000378:metabolism*
chemical_list: D055768:Halogenated Diphenyl Ethers; C010902:decabromobiphenyl ether; D001966:Bromine
keywords: Bioaccumulation; Biotransformation; Cell wall; ChemOffice; Metabolism; Polybrominated diphenyl ether