title: The publication "Cyclohexane-1,2-dicarboxylic acid diisononyl ester and metabolite effects on rat epididymal stromal vascular fraction differentiation of adipose tissue" by Enrico Campioli, Tam B. Duong, François Deschamps, Vassilios Papadopoulos, Environmental Research 140 (2015), 145-156, merits some critical comments.
abstract: In essence, the authors report MINCH, a monoester and minor urinary metabolite (Koch et al., 2013) of a plasticizer marketed by BASF under the brandname Hexamoll(®) DINCH(®), promotes the differentiation of preadipocytes derived from rat epididymal stromal vascular fraction (SVF) to adipocytes. The authors have over-interpreted their in-vitro data and missed important publicly available in-vivo data.
authors.affiliation: BASF SE, E-CPI/R, Carl-Bosch-Str. 38, 67056 Ludwigshafen, Germany.
authors.forename: Rainer
authors.initials: R
authors.lastname: Otter
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects*; D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects*; D003509:Cyclohexanecarboxylic Acids / Q000633:toxicity*; D003998:Dicarboxylic Acids / Q000633:toxicity*; D004822:Epididymis / Q000187:drug effects*; D008297:Male
chemical_list: D003509:Cyclohexanecarboxylic Acids; D003998:Dicarboxylic Acids