title: Prevalence, risk factors, and prognosis of peritoneal metastasis from breast cancer.
abstract: Peritoneal metastasis from breast cancer is a serious and deadly condition only limited considered in the literature. Our aim was to study prevalence, risk factors, and prognosis of breast cancer peritoneal metastasis. We retrospectively analyzed 3096 women with a diagnosis of invasive breast cancer. We took into consideration presence and localization of breast cancer distant metastasis as well as the possible risk factors and survival from the diagnosis of the breast cancer metastasis. The prevalence of breast cancer peritoneal metastases was 0.7 % (22/3096), representing the 7.6 % (22/289) of women affected by distant metastases. Moreover, independent risk factors for breast cancer peritoneal metastases resulted high grading, lobular invasive histology, and advanced T and N stage at diagnosis. Overall survival after metastasis diagnosis was shorter in women affected by peritoneal metastases or brain metastases in comparison to other metastatic women. Breast cancer peritoneal metastases were uncommon but not rare events with a poor prognosis after standard treatments.
authors.affiliation: Clinic of Surgery, AOU "Santa Maria della Misericordia", DISM, DSMB, University of Udine, Piazzale Santa Maria della Misericordia 15, 33100 Udine, UD Italy.|Surgical Oncology Department, IRCSS CRO, Via Franco Gallini, 2, 33081 Aviano, PN Italy.
authors.forename: Serena
authors.identifier: 0000-0003-1173-220X
authors.initials: S
authors.lastname: Bertozzi
authors.affiliation: Unit of Obstetrics and Gynecology, S Polo Hospital, via Galvani 1, 34074 Monfalcone, GO Italy.
authors.forename: Ambrogio P
authors.initials: AP
authors.lastname: Londero
authors.affiliation: Clinic of Surgery, AOU "Santa Maria della Misericordia", DISM, DSMB, University of Udine, Piazzale Santa Maria della Misericordia 15, 33100 Udine, UD Italy.
authors.forename: Carla
authors.initials: C
authors.lastname: Cedolini
authors.affiliation: Clinic of Surgery, AOU "Santa Maria della Misericordia", DISM, DSMB, University of Udine, Piazzale Santa Maria della Misericordia 15, 33100 Udine, UD Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Uzzau
authors.affiliation: Clinic of Surgery, AOU "Santa Maria della Misericordia", DISM, DSMB, University of Udine, Piazzale Santa Maria della Misericordia 15, 33100 Udine, UD Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Seriau
authors.affiliation: Unit of Surgery, Hospital of Latisana, via Sabbionera 45, 33053 Latisana, UD Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Bernardi
authors.affiliation: Clinic of Surgery, AOU "Santa Maria della Misericordia", DISM, DSMB, University of Udine, Piazzale Santa Maria della Misericordia 15, 33100 Udine, UD Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Bacchetti
authors.affiliation: Clinic of Surgery, AOU "Santa Maria della Misericordia", DISM, DSMB, University of Udine, Piazzale Santa Maria della Misericordia 15, 33100 Udine, UD Italy.
authors.forename: Enrico Maria
authors.initials: EM
authors.lastname: Pasqual
authors.affiliation: Clinic of Surgery, AOU "Santa Maria della Misericordia", DISM, DSMB, University of Udine, Piazzale Santa Maria della Misericordia 15, 33100 Udine, UD Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Risaliti
keywords: Breast cancer; Distant metastasis, peritoneal metastasis; Overall survival; Peritoneal carcinomatosis