title: Evaluation of platelet distribution width in chronic obstructive pulmonary disease patients with pulmonary embolism.
abstract: Platelets play an important role in the pathogenesis of pulmonary embolism (PE). We aimed to investigate whether there is a correlation between platelet distribution width (PDW) and chronic obstructive pulmonary disease (COPD) patients with PE.
  
  
  
  We conducted a retrospective study using 126 COPD patients with PE and 51 COPD patients without PE. Blood biomarkers, including PDW and d-dimer, were included. Odds ratios (OR) associated with PDW and interactions with d-dimer, SpO2 were estimated for PE.
  
  
  
  PDW was higher in the COPD patients with PE group (p = 0.007). A higher PDW had a significantly increased risk of PE than a lower PDW (adjusted OR 2.724, 95% CI: 1.290-5.753).
  
  
  
  PDW are elevated in COPD patients with PE and are associated with the risk of PE.
authors.affiliation: Department of Clinical Laboratory, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310000, China.|Department of Biomedical Sciences Laboratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, 322100, China.
authors.forename: Maofeng
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Clinical Laboratory, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310000, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Respiratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, 322100, China.
authors.forename: Qiaoying
authors.initials: Q
authors.lastname: Ji
authors.affiliation: Department of Respiratory, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, 322100, China.
authors.forename: Qiongfang
authors.initials: Q
authors.lastname: Yang
authors.affiliation: Department of Radiology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, 322100, China.
authors.forename: Fenhua
authors.initials: F
authors.lastname: Zhao
authors.affiliation: Department of Cardiology, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, 322100, China.
authors.forename: Weimin
authors.initials: W
authors.lastname: Li
authors.affiliation: Graduate Institute of Basic Medical Science, College of Medicine, China Medical University, Taichung City, 40402, Taiwan.|Department of Computer Science and Information Engineering, Asia University, Taichung City 41354, Taiwan.
authors.forename: Hao-Teng
authors.initials: HT
authors.lastname: Chang
authors.affiliation: Department of Clinical Laboratory, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310000, China.
authors.forename: Xinyou
authors.initials: X
authors.lastname: Xie
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D001792:Blood Platelets / Q000166:cytology*; D017023:Coronary Angiography; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006403:Hematologic Tests; D006801:Humans; D016015:Logistic Models; D020097:Natriuretic Peptide, Brain / Q000032:analysis; D016017:Odds Ratio; D010446:Peptide Fragments / Q000032:analysis; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000175:diagnosis*; D011655:Pulmonary Embolism / Q000150:complications / Q000175:diagnosis*; D012189:Retrospective Studies; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; D010446:Peptide Fragments; C036309:fibrin fragment D; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain
keywords: chronic obstructive pulmonary disease; platelet distribution width; pulmonary embolism