title: Corneal Indocyanine Green Angiography to Guide Medical and Surgical Management of Corneal Neovascularization.
abstract: OBJECTIVE
  To illustrate the role of corneal angiography in the clinical assessment and surgical treatment of patients with complex corneal neovascularization (CoNV).
  
  
  METHODS
  A case series of 3 patients with CoNV is presented whose management was guided by indocyanine green (ICG) and fluorescein corneal angiography. In the first case, there was recurrent lipid exudation into an intrastromal cleft from CoNV; in the second, there was progressive exudation from CoNV at the graft-host interface; in the third, CoNV was associated with rejection after deep anterior lamellar keratoplasty.
  
  
  RESULTS
  In the first case, angiography helped to identify and treat the feeder vessels and stop further leakage. In the second case, it was possible using angiography to differentiate CoNV arising from iris and limbal vasculature enabling angiographic-guided fine-needle diathermy with cessation of exudation. In the third case, angiography revealed the location of CoNV in the host-graft interface after deep anterior lamellar keratoplasty, rather than within the corneal stroma.
  
  
  CONCLUSIONS
  Corneal angiography is a useful diagnostic tool to guide medical and surgical management of CoNV by enabling the localization of vessel depth and topography.
authors.affiliation: *Department of Corneal and External Eye Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom; †Department of Ophthalmology, Medical University of Innsbruck, Innsbruck, Austria; and ‡Department of Eye and Vision Science, University of Liverpool, Liverpool, United Kingdom.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Steger
authors.forename: Vito
authors.initials: V
authors.lastname: Romano
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Kaye
mesh_terms: D000293:Adolescent; D004396:Coloring Agents; D003315:Cornea / Q000098:blood supply*; D016510:Corneal Neovascularization / Q000175:diagnosis* / Q000601:surgery; D016039:Corneal Transplantation; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D057234:Preoperative Period; D055815:Young Adult
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green