title: The socioeconomic profile of a Barrett's oesophagus cohort assessed by the 2010 Index of Multiple Deprivation.
abstract: BACKGROUND
  Several reports have described the relationship between socioeconomic status and oesophageal adenocarcinoma but only one with its precursor condition, Barrett's oesophagus. We therefore investigated such an association.
  
  
  METHODS
  The majority (88%) of patients diagnosed with Barrett's at Rotherham District General Hospital between 28 April 1978 and 31 August 2012 consented to inclusion in the UK Barrett's Oesophagus Registry. Those residing within Rotherham form the basis of this study.
  
  
  METHODS
  We assessed socioeconomic status using the Index of Multiple Deprivation 2010 scores which can be assigned to every English postcode. The scores for the whole of England were divided into five equal groups; those of the 6257 postcodes within Rotherham (including those of Barrett's patients) were compared against the national quintile relevant to their score. We examined the ratio of observed against expected numbers of Barrett's in each quintile before and since 2001, the median year of diagnosis.
  
  
  RESULTS
  The study group comprised 1076 patients with Barrett's oesophagus. Before 2001 their distribution across the deprivation quintiles was similar to that expected. Since then it has changed significantly, with 37% more Barrett's patients than expected among the two least deprived quintiles, but 11% fewer than expected in the larger population comprising the two most deprived quintiles (P=0.0001). There was no significant difference in the distribution of sex (P=0.27), nor the mean age at diagnosis between the two time periods (P=0.92).
  
  
  CONCLUSIONS
  Since 2001, there has been a major change in the distribution of Barrett's in relation to socioeconomic status, measured by the Index of Multiple Deprivation.
authors.affiliation: aUK National Barrett's Oesophagus Registry, Division of Surgery and Interventional Science, University College London, Royal Free Hospital bStatistics, Modelling and Economics Department, Centre for Disease Surveillance and Control, Public Health England, London cDepartment of Gastroenterology, The Rotherham NHS Foundation Trust, Rotherham, UK.
authors.forename: Santanu
authors.initials: S
authors.lastname: Bhattacharjee
authors.forename: Christine P J
authors.initials: CP
authors.lastname: Caygill
authors.forename: Andre
authors.initials: A
authors.lastname: Charlett
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Fox
authors.forename: Piers A C
authors.initials: PA
authors.lastname: Gatenby
authors.forename: Anthony
authors.initials: A
authors.lastname: Watson
authors.forename: Christine
authors.initials: C
authors.lastname: Royston
authors.forename: Karna D
authors.initials: KD
authors.lastname: Bardhan
mesh_terms: D000368:Aged; D001471:Barrett Esophagus / Q000175:diagnosis / Q000191:economics* / Q000453:epidemiology*; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011203:Poverty / Q000639:trends*; D011204:Poverty Areas; D012042:Registries; D012189:Retrospective Studies; D013997:Time Factors