title: The Modalities of Nonadherence to Highly Active Antiretroviral Therapy and the Associated Factors Related to Patients' Sociodemographic Characteristics and Their Caregiving Perceptions in Ouagadougou (Burkina Faso).
abstract: The authors studied the modalities of nonadherence to highly active antiretroviral therapy (HAART) and its sociodemographic associated factors and those in relation to caregiving perception in Ouagadougou.
  
  
  
  A cross-sectional study was performed from December 2013 to February 2014 in 2 health centers. Adults receiving HAART for at least 3 months were included. Adherence was studied according to the quantitative, qualitative, and global criteria. Factors associated with nonadherence were analyzed with chi-square and Fisher tests. A logistic regression model was applied for multivariate analysis.
  
  
  
  The authors studied 152 patients: mean age 40.7 ± 7.8 years and sex ratio 0.34. Frequencies were 7.2% for self-reported quantitative, 20.4% for calculated quantitative, 31.6% for qualitative, and 38.2% for global nonadherence. Married status (P = .02), patient's dissatisfaction regarding clinical monitoring (P = .01), and therapeutic education (P = .03) were associated with nonadherence. In multivariate analysis, married status remains associated (odds ratio = 7.00, 95% confidence interval = 1.89-25.8, P = .0004).
  
  
  
  Nonadherence to HAART needs to be correctly managed during HIV/AIDS monitoring.
authors.affiliation: Unité de Formation et de Recherche en Sciences de la Santé, Université de Ouagadougou, Ouagadougou, Burkina Faso oumgui@yahoo.fr.
authors.forename: Oumar
authors.initials: O
authors.lastname: Guira
authors.affiliation: Centre Médical avec Antenne chirurgicale Saint Camille, Ouagadougou, Burkina Faso.
authors.forename: Delwendé S R
authors.initials: DS
authors.lastname: Kaboré
authors.affiliation: Centre Médical avec Antenne chirurgicale Saint Camille, Ouagadougou, Burkina Faso Centre de Recherche Biomoléculaire Pietro Annigoni, Ouagadougou, Burkina Faso.
authors.forename: Ginette
authors.initials: G
authors.lastname: Dao
authors.affiliation: Centre Médical avec Antenne chirurgicale Saint Camille, Ouagadougou, Burkina Faso Centre de Recherche Biomoléculaire Pietro Annigoni, Ouagadougou, Burkina Faso.
authors.forename: Nicaise
authors.initials: N
authors.lastname: Zagré
authors.affiliation: Centre Médical avec Antenne chirurgicale Saint Camille, Ouagadougou, Burkina Faso Centre de Recherche Biomoléculaire Pietro Annigoni, Ouagadougou, Burkina Faso.
authors.forename: Théodora M
authors.initials: TM
authors.lastname: Zohoncon
authors.affiliation: Centre Médical avec Antenne chirurgicale Saint Camille, Ouagadougou, Burkina Faso Centre de Recherche Biomoléculaire Pietro Annigoni, Ouagadougou, Burkina Faso.
authors.forename: Virginio
authors.initials: V
authors.lastname: Pietra
authors.affiliation: Unité de Formation et de Recherche en Sciences de la Santé, Université de Ouagadougou, Ouagadougou, Burkina Faso.
authors.forename: Joseph Y
authors.initials: JY
authors.lastname: Drabo
authors.affiliation: Centre Médical avec Antenne chirurgicale Saint Camille, Ouagadougou, Burkina Faso Centre de Recherche Biomoléculaire Pietro Annigoni, Ouagadougou, Burkina Faso.
authors.forename: Jacques
authors.initials: J
authors.lastname: Simporé
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D002050:Burkina Faso; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D044966:Anti-Retroviral Agents
keywords: Burkina Faso; HAART; HIV/AIDS; nonadherence