title: Image Quality of Coronary Computed Tomography Angiography with 320-Row Area Detector Computed Tomography in Children with Congenital Heart Disease.
abstract: The objective of this study was to assess factors affecting image quality of 320-row computed tomography angiography (CTA) of coronary arteries in children with congenital heart disease (CHD). We retrospectively reviewed 28 children up to 3 years of age with CHD who underwent prospective electrocardiography (ECG)-gated 320-row CTA with iterative reconstruction. We assessed image quality of proximal coronary artery segments using a five-point scale. Age, body weight, average heart rate, and heart rate variability were recorded and compared between two groups: patients with good diagnostic image quality in all four coronary artery segments and patients with at least one coronary artery segment with nondiagnostic image quality. Altogether, 96 of 112 segments (85.7 %) had diagnostic-quality images. Patients with nondiagnostic segments were significantly younger (10.0 ± 11.6 months) and had lower body weight (5.9 ± 2.9 kg) (each p < 0.05) than patients with diagnostic image quality of all four segments (20.6 ± 13.8 months and 8.4 ± 2.5 kg, respectively; each p < 0.05). Differences in heart rate and heart rate variability between the two imaging groups were not significant. Receiver operating characteristic analyses for predicting patients with nondiagnostic image quality revealed an optimal body weight cutoff of ≤5.6 kg and an optimal age cutoff of ≤12.5 months. Prospective ECG-gated 320-row CTA with iterative reconstruction provided feasible image quality of coronary arteries in children with CHD. Younger age and lower body weight were factors that led to poorer image quality of coronary arteries.
authors.affiliation: Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan. tada-a@cc.okayama-u.ac.jp.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tada
authors.affiliation: Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan.
authors.forename: Shuhei
authors.initials: S
authors.lastname: Sato
authors.affiliation: Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Kanie
authors.affiliation: Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Tanaka
authors.affiliation: Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan.
authors.forename: Ryota
authors.initials: R
authors.lastname: Inai
authors.affiliation: Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan.
authors.forename: Noriaki
authors.initials: N
authors.lastname: Akagi
authors.affiliation: Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Morimitsu
authors.affiliation: Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Kanazawa
mesh_terms: D002675:Child, Preschool; D000072226:Computed Tomography Angiography; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006339:Heart Rate; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D015588:Observer Variation; D012372:ROC Curve; D011829:Radiation Dosage; D012189:Retrospective Studies
keywords: 320-row CT; Congenital heart disease; Coronary CT angiography; ECG gated; Prospective