title: Do the Symptoms of Kleine-Levin Syndrome Correlate With the Hypometabolism of the Thalamus on FDG PET?
abstract: A 15-year-old adolescent boy had experienced intermittent, recurrent hypersomnia lasting for 1 week to 3 weeks for more than 3 years. He was diagnosed with Kleine-Levin Syndrome clinically. The brain MRI, video EEG, and serum and cerebrospinal fluid analysis did not show any abnormality. An FDG PET/CT scanning was acquired when the patient was symptomatic, showing marked symmetric hypometabolism in the thalamus and hypothalamus in the symptomatic phase, as well as mild homogeneous decreased glucose metabolism in the cortex. Interestingly, another FDG PET/CT scan acquired when the patient was asymptomatic found much less severe hypometabolism in the thalamus and hypothalamus.
authors.affiliation: From the Department of Nuclear Medicine, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, China.
authors.forename: Hongjun
authors.initials: H
authors.lastname: Xie
authors.forename: Jia
authors.initials: J
authors.lastname: Guo
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
authors.forename: Wenzhong
authors.initials: W
authors.lastname: Song
mesh_terms: D000293:Adolescent; D019788:Fluorodeoxyglucose F18; D006801:Humans; D017593:Kleine-Levin Syndrome / Q000000981:diagnostic imaging*; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013788:Thalamus / Q000000981:diagnostic imaging* / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18