title: Nutrient interface with biology and aging.
abstract: OBJECTIVE
  To highlight recent conundrums in the interface of nutrition, biology and aging.
  
  
  RESULTS
  A Mediterranean diet with extra virgin olive oil, or similar plant-based diets, including five helpings of fruit and vegetables, exercise and nonsmoking are the mainstays of aging successfully. Recent studies have questioned the utility of weight loss in older persons, the use of antioxidant vitamin supplements as well as the appropriate level of sodium intake. The understanding of the role of ethnicity in the levels of vitamin D-binding protein has questioned the measurement of 25(OH)vitamin D by itself. Gut microbiota may also appear important for aging.
  
  
  CONCLUSIONS
  Continuous scientific advances are leading us to question whether some of our nutrient beliefs need to be altered in older persons.
authors.affiliation: aDepartment of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University bDepartment of Geriatric Medicine, Uppsala University Hospital, Uppsala, Sweden cDivisions of Geriatric Medicine and Endocrinology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
authors.forename: Tommy
authors.initials: T
authors.lastname: Cederholm
authors.forename: John E
authors.initials: JE
authors.lastname: Morley
mesh_terms: D000375:Aging / Q000502:physiology*; D004032:Diet; D019587:Dietary Supplements; D006801:Humans; D009752:Nutritional Status