title: An extraneural primary anaplastic ependymoma at the subcutaneous inguinal region: Report of a rare case.
abstract: Ependymomas commonly arise in the central nervous system. Extraneural presentation is quite rare. Herein, we describe a primary extraneural ependymoma in a young female. The mass was located in the right inguinal area. The cut surface of the 7.5 mm × 6.5 mm × 4.5 mm sized tumor was brownish-yellow in color. Histologically, it was hypercellular exhibiting pseudorosette or rosette formations and some papillary structures. Mitosis was counted as high as 10 per 10 high power fields. Neither necrosis nor vascular endothelial proliferation within the tumor was observed. Tumor cells showed strong glial fibrillary acidic protein immunoreactivity. On epithelial membrane antigen, intracytoplasmic dot-like immunostaining was observed. This is the first report presenting a primary extraneural anaplastic ependymoma arising in the inguinal subcutaneous region.
authors.affiliation: Department of Pathology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.
authors.forename: Hamide
authors.initials: H
authors.lastname: Sayar
authors.forename: Ayca
authors.initials: A
authors.lastname: Ersen
authors.forename: Neslihan
authors.initials: N
authors.lastname: Kurtul
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Yazar
authors.forename: Ozan
authors.initials: O
authors.lastname: Balakan
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D014408:Biomarkers, Tumor / Q000378:metabolism*; D004806:Ependymoma / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D006801:Humans; D007264:Inguinal Canal / Q000473:pathology; D018396:Mucin-1 / Q000378:metabolism; D040521:Subcutaneous Tissue / Q000473:pathology; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor; D005904:Glial Fibrillary Acidic Protein; D018396:Mucin-1