title: Lichens as natural sources of biotechnologically relevant bacteria.
abstract: The search for microorganisms from novel sources and in particular microbial symbioses represents a promising approach in biotechnology. In this context, lichens have increasingly become a subject of research in microbial biotechnology, particularly after the recognition that a diverse community of bacteria other than cyanobacteria is an additional partner to the traditionally recognized algae-fungus mutualism. Here, we review recent studies using culture-dependent as well as culture-independent approaches showing that lichens can harbor diverse bacterial families known for the production of compounds of biotechnological interest and that several microorganisms isolated from lichens, in particular Actinobacteria and Cyanobacteria, can produce a number of bioactive compounds, many of them with biotechnological potential.
authors.affiliation: Sorbonne Universités, UPMC Univ. Paris 06, CNRS, Laboratoire de Biodiversité et Biotechnologie Microbiennes (LBBM), Observatoire Océanologique, F-66650, Banyuls/Mer, France. suzuki@obs-banyuls.fr.
authors.forename: Marcelino T
authors.identifier: http://orcid.org/0000-0003-3868-6362
authors.initials: MT
authors.lastname: Suzuki
authors.affiliation: UMR CNRS 6226, Institut des Sciences chimiques de Rennes, Equipe PNSCM "Produits Naturels - Synthèses - Chimie Médicinale", UFR Sciences Pharmaceutiques et Biologiques, Univ. Rennes 1, Université Européenne de Bretagne, 2 Avenue du Pr. Léon Bernard, F-35043, Rennes, France.
authors.forename: Delphine
authors.initials: D
authors.lastname: Parrot
authors.affiliation: Institute of Environmental Biotechnology, Graz University of Technology, Petersgasse 12, 8010, Graz, Austria.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Berg
authors.affiliation: Institute of Plant Sciences, University of Graz, Holteigasse 6, Graz, Austria.
authors.forename: Martin
authors.initials: M
authors.lastname: Grube
authors.affiliation: UMR CNRS 6226, Institut des Sciences chimiques de Rennes, Equipe PNSCM "Produits Naturels - Synthèses - Chimie Médicinale", UFR Sciences Pharmaceutiques et Biologiques, Univ. Rennes 1, Université Européenne de Bretagne, 2 Avenue du Pr. Léon Bernard, F-35043, Rennes, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Tomasi
mesh_terms: D039903:Actinobacteria / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D001709:Biotechnology; D000458:Cyanobacteria / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D005658:Fungi / Q000235:genetics / Q000378:metabolism; D008011:Lichens / Q000235:genetics / Q000382:microbiology*; D059013:Microbial Consortia; D013559:Symbiosis
keywords: Actinobacteria; Bacteria; Biotechnology; Cyanobacteria; Lichens