title: Secondary neurolymphomatosis of spinal nerve roots detected by ¹⁸F-FDG PET/CT: a case report and differential diagnosis of the case.
abstract: OBJECTIVE
  Neurolymphomatosis (NL) is a rare neurological manifestation of lymphoma. Clinical symptoms of NL differ greatly according to the sites involved and diagnosis with conventional imaging techniques may sometimes be difficult. We herein describe the case of a 58 years old man presenting as radiculopathy with a history of non-Hodgkin's lymphoma (NHL). Computed tomography (CT) was unrevealing and magnetic resonance imaging (MRI) was contraindicated. Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) was performed and revealed multiple hypermetabolic lesions along the nerve roots, which corresponded to the patient's neurological symptoms. A differential diagnosis of patients with lymphomatous involvement of spinal nerve roots has been presented.
  
  
  CONCLUSIONS
  Our case suggests that ¹⁸F-FDG PET/CT successfully detected the infiltration of spinal nerve roots of NL due to lymphoma.
authors.affiliation: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China. drmaxuelei@gmail.com.
authors.forename: Yihan
authors.initials: Y
authors.lastname: Wang
authors.forename: JianChao
authors.initials: J
authors.lastname: Wang
authors.forename: Chong
authors.initials: C
authors.lastname: Jiang
authors.forename: Qian
authors.initials: Q
authors.lastname: Peng
authors.forename: Mingpeng
authors.initials: M
authors.lastname: Wu
authors.forename: Xuelei
authors.initials: X
authors.lastname: Ma
mesh_terms: D003287:Contrast Media; D003937:Diagnosis, Differential; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods; D009361:Neoplasm Invasiveness; D010523:Peripheral Nervous System Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D013126:Spinal Nerve Roots / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18