title: Association between the abdominal obesity anthropometric indicators and metabolic disorders in a Chinese population.
abstract: BACKGROUND
  Obesity has become a major health problem in contemporary society and it is closely related to many chronic diseases, so it is an important issue for measuring adiposity accurately and predicting its future. Prevention and treatment of overweight and obesity has become one of the key prevention and treatment of metabolic disorders.
  
  
  OBJECTIVE
  In this study, we compared the ability of the four anthropometric indicators (body mass index, waist circumstance, waist-height ratio, waist-to-hip ratio) to identify metabolic disorders (hypertension, hyperlipidaemia, hyperglycemia and hyperuricemia) by receiver operating characteristic (ROC) curve analyses and to provide evidence for clinical practice.
  
  
  METHODS
  In this large scale cross-sectional study, 13,275 Han adults (including 7595 males and 5680 females) received physical examination between January, 2009 and January, 2010 in Xuanwu Hospital of Capital Medical University were investigated by the means of questionnaire, Meanwhile, the physical examination and serological results were recorded. A package known as Statistical Package for Social Scientist (SPSS) was employed to analyse the responses while t-test, one-way analysis of variance (ANOVA), ROC analysis and chi-square statistical methods were used to test the hypotheses.
  
  
  RESULTS
  WC, WHtR, WHR and BMI were all significantly (P < 0.001) correlated with all metabolic risk factors regardless of gender. And the area under the curve (AUC) of WHtR was significantly greater than that of WC, BMI or WHR in the prediction of hypertension, hyperlipidaemia, hyperglycemia and hyperuricemia.
  
  
  CONCLUSIONS
  Our data show that WHtR was the best predictor of various metabolic disorders. The diagnostic value in descending order was WHtR > WHR > WC > BMI. Therefore we recommend WHtR in assessment of obese patients, in order to better assess the risks of their metabolic diseases.
authors.affiliation: Physical Examination Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: J
authors.initials: J
authors.lastname: Dong
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, China.
authors.forename: Y-Q
authors.initials: YQ
authors.lastname: Ni
authors.affiliation: Physical Examination Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: X
authors.initials: X
authors.lastname: Chu
authors.affiliation: Physical Examination Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Y-Q
authors.initials: YQ
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, China; Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
authors.forename: G-X
authors.initials: GX
authors.lastname: Liu
authors.affiliation: Physical Examination Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: J
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Department of Thoracic Surgery I, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Beijing Cancer Hospital, Peking University School of Oncology, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. Electronic address: yyb997@126.com.
authors.forename: Y-B
authors.initials: YB
authors.lastname: Yang
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, China; Municipal Key Laboratory of Clinical Epidemiology, Beijing, China. Electronic address: yanyxepi@ccmu.edu.cn.
authors.forename: Y-X
authors.initials: YX
authors.lastname: Yan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000886:Anthropometry; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000453:epidemiology*; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000453:epidemiology*; D012307:Risk Factors; D055105:Waist Circumference; D065927:Waist-Height Ratio; D049629:Waist-Hip Ratio; D055815:Young Adult
keywords: Abdominal obesity; Body mass index (BMI); Hyperglycemia; Hyperlipidaemia; Hypertension; Hyperuricemia; Waist circumference (WC); Waist-to-hip ratio (WHR); Waist–height ratio (WHtR)