title: Management of thyroid gland invasion in laryngeal and hypopharyngeal squamous cell carcinoma.
abstract: The objective of this study was to determine the incidence of thyroid gland invasion in laryngeal and hypopharyngeal squamous cell carcinoma; and the association between clinicopathological parameters and thyroid gland invasion. Medical records of 75 patients with laryngeal and hypopharyngeal squamous cell carcinoma who underwent total laryngectomy with thyroidectomy were reviewed, retrospectively. Preoperative computed tomography scans, clinical and operative findings, and histopathological data of the specimens were evaluated. There were 73 male and two female patients with an age range of 41-88 years (mean 60.4 years). Hemithyroidectomy was performed in 62 (82.7 %) and total thyroidectomy was performed in 13 patients (17.3 %). Four patients had histopathologically proven thyroid gland invasion (5.3 %). In three patients, thyroid gland involvement was by means of direct invasion. Thyroid gland invasion was significantly correlated with thyroid cartilage invasion. Therefore, prophylactic thyroidectomy should not be a part of the treatment policy for these tumors.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, İzmir Atatürk Research and Training Hospital, İzmir, Turkey. secilarslanoglu@hotmail.com.
authors.forename: Seçil
authors.initials: S
authors.lastname: Arslanoğlu
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, İzmir Atatürk Research and Training Hospital, İzmir, Turkey.
authors.forename: Erdem
authors.initials: E
authors.lastname: Eren
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, İzmir Atatürk Research and Training Hospital, İzmir, Turkey.
authors.forename: Yılmaz
authors.initials: Y
authors.lastname: Özkul
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, İzmir Atatürk Research and Training Hospital, İzmir, Turkey.
authors.forename: Ejder
authors.initials: E
authors.lastname: Ciğer
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, İzmir Atatürk Research and Training Hospital, İzmir, Turkey.
authors.forename: Aylin
authors.initials: A
authors.lastname: Kopar
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, İzmir Atatürk Research and Training Hospital, İzmir, Turkey.
authors.forename: Kazım
authors.initials: K
authors.lastname: Önal
authors.affiliation: Department of Pathology, İzmir Atatürk Research and Training Hospital, İzmir, Turkey.
authors.forename: Demet
authors.initials: D
authors.lastname: Etit
authors.affiliation: Department of Mathematics, İzmir University of Economics, İzmir, Turkey.
authors.forename: G Yazgı
authors.initials: GY
authors.lastname: Tütüncü
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019468:Disease Management; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D015994:Incidence; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012189:Retrospective Studies; D013961:Thyroid Gland / Q000473:pathology* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*; D014057:Tomography, X-Ray Computed
keywords: Hypopharynx; Larynx; Squamous cell carcinoma; Thyroid gland