title: Viral Infection in Adults with Severe Acute Respiratory Infection in Colombia.
abstract: OBJECTIVE
  To identify the viral aetiology in adult patients with severe acute respiratory infection (SARI) admitted to sentinel surveillance institutions in Bogotá in 2012.
  
  
  METHODS
  A cross-sectional study was conducted in which microarray molecular techniques for viral identification were used on nasopharyngeal samples of adult patients submitted to the surveillance system, and further descriptions of clinical features and relevant clinical outcomes, such as mortality, need for critical care, use of mechanical ventilation and hospital stay, were obtained.
  
  
  METHODS
  Respiratory infections requiring hospital admission in surveillance centres in Bogotá, Colombia.
  
  
  METHODS
  Ninety-one adult patients with acute respiratory infection (55% were female).
  
  
  METHODS
  Viral identification, intensive care unit admission, hospital stay, and mortality.
  
  
  RESULTS
  Viral identification was achieved for 63 patients (69.2%). Comorbidity was frequently identified and mainly involved chronic pulmonary disease or pregnancy. Influenza, Bocavirus and Adenovirus were identified in 30.8%, 28.6% and 18.7% of the cases, respectively. Admission to the intensive care unit occurred in 42.9% of the cases, while mechanical ventilation was required for 36.3%. The average hospital stay was 9.9 days, and mortality was 15.4%. Antibiotics were empirically used in 90.1% of patients.
  
  
  CONCLUSIONS
  The prevalence of viral aetiology of SARI in this study was high, with adverse clinical outcomes, intensive care requirements and high mortality.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, National University of Colombia, Bogotá, Colombia.
authors.forename: Yuly Andrea
authors.initials: YA
authors.lastname: Remolina
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, National University of Colombia, Bogotá, Colombia.
authors.forename: María Mercedes
authors.initials: MM
authors.lastname: Ulloa
authors.affiliation: Public Health Laboratory, District Health Department, Bogota, Colombia.
authors.forename: Hernán
authors.initials: H
authors.lastname: Vargas
authors.affiliation: Public Health Laboratory, District Health Department, Bogota, Colombia.
authors.forename: Liliana
authors.initials: L
authors.lastname: Díaz
authors.affiliation: Public Health Laboratory, District Health Department, Bogota, Colombia.
authors.forename: Sandra Liliana
authors.initials: SL
authors.lastname: Gómez
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, National University of Colombia, Bogotá, Colombia.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Saavedra
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, National University of Colombia, Bogotá, Colombia.
authors.forename: Edgar
authors.initials: E
authors.lastname: Sánchez
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, National University of Colombia, Bogotá, Colombia.|Infectious Disease Research Group, Faculty of Medicine, National University of Colombia, Bogotá, Colombia.
authors.forename: Jorge Alberto
authors.initials: JA
authors.lastname: Cortés
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003105:Colombia / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology*; D012621:Seasons; D016896:Treatment Outcome; D055815:Young Adult