title: Electrochemical primer extension for the detection of single nucleotide polymorphisms in the cardiomyopathy associated MYH7 gene.
abstract: We report the labelling of dideoxy nucleotides (ddNTPs) for use in electrochemical array based primer extension for the detection of single nucleotide polymorphisms (SNPs). The results confirm the extension of the immobilised primers for each of the four ddNTPs, representing a significant advance in achieving a cost-effective platform for screening of disease-specific SNPs.
authors.affiliation: Departament d'Enginyeria Química, Universitat Rovira i Virgili, Avinguda Països Catalans 26, 43007 Tarragona, Spain. mayreli.ortiz@urv.cat ckosulli@etse.urv.es and Sorbonne Universités, UPMC Univ Paris 06 Institut Parisien de Chimie Moléculaire, UMR CNRS 8232, 4 place Jussieu, 75005 Paris, France.
authors.forename: A M
authors.initials: AM
authors.lastname: Debela
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06 Institut Parisien de Chimie Moléculaire, UMR CNRS 8232, 4 place Jussieu, 75005 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Thorimbert
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06 Institut Parisien de Chimie Moléculaire, UMR CNRS 8232, 4 place Jussieu, 75005 Paris, France.
authors.forename: B
authors.initials: B
authors.lastname: Hasenknopf
authors.affiliation: Departament d'Enginyeria Química, Universitat Rovira i Virgili, Avinguda Països Catalans 26, 43007 Tarragona, Spain. mayreli.ortiz@urv.cat ckosulli@etse.urv.es and ICREA, Passeig Lluis Companys 23, 08010 Barcelona, Spain.
authors.forename: C K
authors.initials: CK
authors.lastname: O'Sullivan
authors.affiliation: Departament d'Enginyeria Química, Universitat Rovira i Virgili, Avinguda Països Catalans 26, 43007 Tarragona, Spain. mayreli.ortiz@urv.cat ckosulli@etse.urv.es.
authors.forename: M
authors.initials: M
authors.lastname: Ortiz