title: [Evidence-based therapy of polycystic ovarian syndrome].
abstract: Polycystic ovary syndrome is recognized as the most common hormonal and metabolic disorder likely to affect women. The heterogeneous endocrinopathy is characterized by clinical and/or biochemical hyperandrogenism, oligo- or amenorrhoea, anovulatory infertility, and polycystic ovarian morphology. The syndrome is often associated with obesity, hyperinsulinemia and adversely affects endocrine, metabolic, and cardiovascular health. The symptoms and complaint of the patients vary with age. To maximise health gain of the syndrome, adequate, evidence based effective, efficient and safe treatment is necessary. This article summarises the highest available evidence provided by studies, meta-analysis and systematic reviews about the therapeutical possibilities for treating obesity, hyperandrogenism, menstrual abnormalities, infertility and psychological problems related to polycystic ovary syndrome.
authors.affiliation: Megelőző Orvostani Intézet, Debreceni Egyetem, Népegészségügyi Kar Debrecen, Kassai u. 26., 4028.
authors.forename: Sándor
authors.initials: S
authors.lastname: Gődény
authors.affiliation: Megelőző Orvostani Intézet, Debreceni Egyetem, Népegészségügyi Kar Debrecen, Kassai u. 26., 4028.
authors.forename: Orsolya Karola
authors.initials: OK
authors.lastname: Csenteri
mesh_terms: D000568:Amenorrhea / Q000188:drug therapy / Q000209:etiology; D000726:Androgen Antagonists / Q000627:therapeutic use*; D000858:Anovulation / Q000188:drug therapy / Q000209:etiology; D019440:Anti-Obesity Agents / Q000627:therapeutic use*; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D003278:Contraceptives, Oral, Hormonal / Q000627:therapeutic use*; D003863:Depression / Q000209:etiology / Q000628:therapy; D019317:Evidence-Based Medicine; D005260:Female; D006628:Hirsutism / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D017588:Hyperandrogenism / Q000209:etiology; D006946:Hyperinsulinism / Q000188:drug therapy / Q000209:etiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007247:Infertility, Female / Q000188:drug therapy / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D007333:Insulin Resistance; D008687:Metformin / Q000627:therapeutic use; D009765:Obesity / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000523:psychology / Q000601:surgery / Q000628:therapy*; D040242:Risk Reduction Behavior
chemical_list: D000726:Androgen Antagonists; D019440:Anti-Obesity Agents; D006063:Chorionic Gonadotropin; D003278:Contraceptives, Oral, Hormonal; D007004:Hypoglycemic Agents; D008687:Metformin
keywords: EBM; PCOS; clinical features; klinikai tünetek; terápia; therapy