title: [Prognostic Factors in Guillain-Barré Syndrome].
abstract: Clinical outcome of Guillain-Barré syndrome (GBS) is poorer than may be expected, despite recent applications of plasmapheresis and IVIg. Among prognostic factors of GBS, clinical factors are more useful compared to electrophysiological or biological factors. To improve the outcome of GBS patients with poor prognoses, a worldwide prospective survey (IGOS, International GBS Outcome Study) and a Japanese prospective GBS outcome study (JGOS) have been conducted. These surveys make it possible to define biomarkers for disease activity and recovery, and to develop prognostic models to precisely predict the clinical course and outcome in individual patients in the early stage of the disease.
authors.affiliation: Division of Neurology, Department of Internal Medicine, National Defense Medical College.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kaida
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D016756:Immunoglobulins, Intravenous