title: [Recovery of Cushing syndrome revealing McCune-Albright syndrome].
abstract: Cushing syndrome (CS) is a rare feature of McCune-Albright syndrome. Treatments consist of bilateral adrenalectomy followed by lifelong glucocorticoid and mineralocorticoid treatment. However, cases of spontaneous remission of CS have been reported in the literature. We report a case of McCune-Albright syndrome with CS treated with metyrapone for 30 months with prolonged remission after a 12-year follow-up. Adrenalectomy may be avoided in some cases of CS caused by McCune-Albright syndrome. Metyrapone could be a good alternative to surgical treatment.
authors.affiliation: Service de pédiatrie, hôpital Mongi Slim La Marsa, faculté de médecine de Tunis, université de Tunis El Manar, La Marsa, Tunisie. Electronic address: sonia.halioui@rns.tn.
authors.forename: S
authors.initials: S
authors.lastname: Halioui-Louhaichi
authors.affiliation: Service de pédiatrie, hôpital Mongi Slim La Marsa, faculté de médecine de Tunis, université de Tunis El Manar, La Marsa, Tunisie.
authors.forename: Y
authors.initials: Y
authors.lastname: Dridi
authors.affiliation: Service de pédiatrie, hôpital Mongi Slim La Marsa, faculté de médecine de Tunis, université de Tunis El Manar, La Marsa, Tunisie.
authors.forename: O
authors.initials: O
authors.lastname: Azzabi
authors.affiliation: Service de pédiatrie, hôpital Mongi Slim La Marsa, faculté de médecine de Tunis, université de Tunis El Manar, La Marsa, Tunisie.
authors.forename: I
authors.initials: I
authors.lastname: Selmi
authors.affiliation: Service de pédiatrie, hôpital Mongi Slim La Marsa, faculté de médecine de Tunis, université de Tunis El Manar, La Marsa, Tunisie.
authors.forename: I
authors.initials: I
authors.lastname: Fetni
authors.affiliation: Service de pédiatrie, hôpital Mongi Slim La Marsa, faculté de médecine de Tunis, université de Tunis El Manar, La Marsa, Tunisie.
authors.forename: N
authors.initials: N
authors.lastname: Siala
authors.affiliation: Service de pédiatrie, hôpital Mongi Slim La Marsa, faculté de médecine de Tunis, université de Tunis El Manar, La Marsa, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Maherzi
mesh_terms: D002648:Child; D003480:Cushing Syndrome / Q000188:drug therapy* / Q000209:etiology; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D005260:Female; D005359:Fibrous Dysplasia, Polyostotic / Q000150:complications*; D005500:Follow-Up Studies; D006801:Humans; D008797:Metyrapone / Q000627:therapeutic use*; D012074:Remission Induction
chemical_list: D004791:Enzyme Inhibitors; D008797:Metyrapone