title: Natural Products as Source of Therapeutics against Parasitic Diseases.
abstract: An end to suffering: Parasitic infections with protozoa and worms cause unimaginable misery, in particular in the tropics. Fortunately, natural products, such as the antimalarial artemisinin (1) and the anthelmintic avermectin (2) were discovered and developed into therapeutics. These major achievements now culminated in the 2015 Nobel Prize for Medicine.
authors.affiliation: Department of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Beutenbergstr. 11a, 07745 Jena (Germany). christian.hertweck@leibniz-hki.de.|Chair for Natural Product Chemistry, Friedrich Schiller University, Jena (Germany). christian.hertweck@leibniz-hki.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Hertweck
mesh_terms: D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008968:Molecular Conformation; D010272:Parasitic Diseases / Q000188:drug therapy*; D021261:Parasitic Sensitivity Tests; D013302:Streptomyces / Q000187:drug effects
chemical_list: D001688:Biological Products
keywords: Nobel Prize; antiparasitics; artemisinin; avermectin; malaria; natural products