title: Application of Efficient Nanoparticles for Early Diagnosis and Treatment of Cancer.
abstract: Cancer is considered as a prevalent cause of human deaths and undoubtedly, is the most complex disease with multiple cellular physiological systems involved. During the last decade, the application of nanotechnological products for cancer treatment has received considerable attention. These sophisticated tools and materials treat cancer though the early diagnosis, the prediction, the prevention and the personalized therapy. This technology enabled the development of nanoscale particles that can be conjugated with one or multiple functional molecules simultaneously. Nanoparticles have the capability to be delivered directly through blood vessels to the tumor site and interact with targeted tumor-specific proteins located inside or on the surface of cancer cells, since their size is a hundred to thousand times smaller than cancer cells. In this review, comprehensive outline of all the latest scientific and technological applications such as quantum dots and gold nanoparticles alongside with their applications in cancer diagnosis and treatment have been presented.
authors.affiliation: PostDoc Fellow Researcher, Bioinformatics & Human Electrophysiology Laboratory, Department of Informatics, IonianUniversity, Plateia Tsirigoti 7, 49100 Corfu, Greece. alexiou@ionio.gr.
authors.forename: Athanasios
authors.initials: A
authors.lastname: Alexiou
authors.forename: Charalampos
authors.initials: C
authors.lastname: Vairaktarakis
authors.forename: Vasilis
authors.initials: V
authors.lastname: Tsiamis
authors.forename: Ghulam Md
authors.initials: GM
authors.lastname: Ashraf
mesh_terms: D000818:Animals; D055088:Early Detection of Cancer; D006046:Gold / Q000627:therapeutic use*; D006801:Humans; D053768:Metal Nanoparticles / Q000627:therapeutic use*; D009369:Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D045663:Quantum Dots / Q000627:therapeutic use*
chemical_list: D006046:Gold