title: First case of congenital idiopathic hypohidrosis in China.
abstract: A 43-year-old Chinese man presented with generalized hypohidrosis, which he had had since birth, without obvious abnormalities of other skin appendages except a sparse beard and axillary hairs. The sweat test revealed localized sweating on the face, axillae and palms. Histopathologic examination showed that the sweat glands were absent in the forearm and thigh, but some eccrine and apocrine sweat glands were present in the right axilla. S-100 was expressed in the nerve terminals surrounding the acini and ducts of the eccrine sweat glands, while PGP9.5 was positive in the acini of apocrine glands and the nerve terminals surrounding the eccrine glands in the axilla. To our knowledge, this is the first case of congenital idiopathic hypohidrosis in China.
authors.affiliation: Guangdong Medical College, Guangdong, China.
authors.forename: Ge
authors.initials: G
authors.lastname: Shi
authors.affiliation: Guangdong Medical College, Guangdong, China.
authors.forename: Cheng-Yao
authors.initials: CY
authors.lastname: Zhu
authors.affiliation: Guangdong Medical College, Guangdong, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Guangdong Medical College, Guangdong, China.
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Yang
authors.affiliation: Guangdong Medical College, Guangdong, China.
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Fan
mesh_terms: D000328:Adult; D001050:Apocrine Glands / Q000002:abnormalities* / Q000473:pathology; D001365:Axilla; D002681:China; D004439:Eccrine Glands / Q000002:abnormalities* / Q000473:pathology; D006801:Humans; D007007:Hypohidrosis / Q000151:congenital* / Q000473:pathology*; D007150:Immunohistochemistry; D008297:Male