title: A review of the current and potential oxygen delivery systems and techniques utilized in cluster headache attacks.
abstract: BACKGROUND
  Despite oxygen therapy being one of the foremost acute treatments for cluster headache (CH) attacks, little is known about the different techniques and systems.
  
  
  OBJECTIVE
  In this review we will examine the efficacy of the standard non-rebreather mask (NRM) with room temperature oxygen in relieving pain in CH, and try to compare it with the diversity of other oxygen gas conditions and interfaces like partial rebreathers, simple masks, nasal cannulas, tusk masks, demand valve oxygen, hyperbaric and cooled oxygen.
  
  
  METHODS
  We searched non-structured Pubmed, Medline, the Cochrane online database and instruction protocols from various oxygen delivery devices.
  
  
  CONCLUSIONS
  Interfaces like demand valves and tusk masks are already proving to be superior or at least similar to the standard NRM in terms of fraction of inspired oxygen (FiO2), though the demand valve only showed better results than the NRM in a single study in only four participants. Furthermore, new research shows how lower temperatures of the gas may be an essential part of effective pain relief and hyperbaric treatments show potential in preventing night time attacks.
authors.affiliation: Department of Neurology, Atrium Medical Centre, Henri Dunantstraat 5, 6419 PC Heerlen, The Netherlands jerome.c.oudenijhuis@gmail.com.
authors.forename: Jerome C
authors.initials: JC
authors.lastname: Oude Nijhuis
authors.affiliation: Department of Neurology, Atrium Medical Centre, Henri Dunantstraat 5, 6419 PC Heerlen, The Netherlands.
authors.forename: Danielle Yp
authors.initials: DY
authors.lastname: Haane
authors.affiliation: Department of Neurology, Atrium Medical Centre, Henri Dunantstraat 5, 6419 PC Heerlen, The Netherlands.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Koehler
mesh_terms: D003027:Cluster Headache / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D016503:Drug Delivery Systems / Q000639:trends*; D006801:Humans; D008397:Masks / Q000706:statistics & numerical data / Q000639:trends*; D010100:Oxygen / Q000008:administration & dosage*; D010102:Oxygen Inhalation Therapy / Q000379:methods / Q000639:trends*
chemical_list: D010100:Oxygen
keywords: CPAP; cluster headache; demand valve oxygen; fraction of inspired oxygen; hyperbaric oxygen therapy; nasal cannula; non-rebreather mask; oxygen delivery system; oxygen temperature; oxygen therapy; simple mask; tusk mask