title: Osseous Metaplasia and Subsequent Spontaneous Pregnancy Chance: A Case Report and Review of the Literature.
abstract: BACKGROUND
  What is not clear as yet is not only the etiology, but also the management of osseous metaplasia. We describe an infertile patient with osseous metaplasia and subsequent pregnancy after treatment and review the literature from infertility perspective.
  
  
  METHODS
  We presented a 30-year-old woman with 8 years of secondary infertility who conceived spontaneously after removal of osseous tissue by operative hysteroscopy (HS) following one failed in vitro fertilization cycle. The current literature regarding the osseous metaplasia and fertility potential after removal of osseous tissue was also systematically reviewed in which 21 reports (n = 64 women) were eligible.
  
  
  RESULTS
  The available data suggest that restoration of endometrial cavity with HS or curettage provides a spontaneous pregnancy rate of 54.2% within 12 months.
  
  
  CONCLUSIONS
  According to the available data, irrespective from the duration of subfertility, spontaneous pregnancy should be expected for at least 1 year following the 'complete' restoration of endometrial cavity. In that context, further infertility treatments such as assisted reproduction cycles should be postponed, unless there is another reason for infertility.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Gurkan
authors.initials: G
authors.lastname: Bozdag
authors.forename: Sezcan
authors.initials: S
authors.lastname: Mumusoglu
authors.forename: Selen
authors.initials: S
authors.lastname: Dogan
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Esinler
authors.forename: Serdar
authors.initials: S
authors.lastname: Gunalp
mesh_terms: D000328:Adult; D003475:Curettage; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D007247:Infertility, Female / Q000209:etiology / Q000601:surgery*; D008679:Metaplasia / Q000601:surgery; D009999:Ossification, Heterotopic / Q000150:complications / Q000601:surgery*; D011247:Pregnancy; D014591:Uterine Diseases / Q000150:complications / Q000601:surgery*