title: Visible-Light/Photoredox-Mediated sp(3) C-H Functionalization and Coupling of Secondary Amines with Vinyl Azides in Flow Microreactors.
abstract: Structurally diverse imidazole derivatives were synthesized by a visible-light/[Ru(bpy)3 ][(PF6 )2 ]-mediated coupling of vinyl azides and secondary amines in flow microreactors. This operationally simple and atom-economical protocol allows the formation of three new C-N bonds through the functionalization of sp(3)  C-H bonds adjacent to the secondary nitrogen atom. In order to get mechanistic insight of the coupling reaction, several control experiments were carried out and discussed.
authors.affiliation: Department of Inorganic and Physical Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007 (India). dktiwari.iict@gov.in.
authors.forename: Dharmendra Kumar
authors.initials: DK
authors.lastname: Tiwari
authors.affiliation: Department of Medicinal Chemistry and Pharmacology, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007 (India). ramaurya.iict@gov.in.
authors.forename: Ram Awatar
authors.initials: RA
authors.lastname: Maurya
authors.affiliation: Centre for X-ray Crystallography, CSIR-Indian Institute of Chemical Technology, Hyderabad-500007 (India).
authors.forename: Jagadeesh Babu
authors.initials: JB
authors.lastname: Nanubolu
keywords: azides; nitrogen heterocycles; oxidation; photochemistry; redox chemistry; visible light