title: Coherence resonance in bursting neural networks.
abstract: Synchronized neural bursts are one of the most noticeable dynamic features of neural networks, being essential for various phenomena in neuroscience, yet their complex dynamics are not well understood. With extrinsic electrical and optical manipulations on cultured neural networks, we demonstrate that the regularity (or randomness) of burst sequences is in many cases determined by a (few) low-dimensional attractor(s) working under strong neural noise. Moreover, there is an optimal level of noise strength at which the regularity of the interburst interval sequence becomes maximal-a phenomenon of coherence resonance. The experimental observations are successfully reproduced through computer simulations on a well-established neural network model, suggesting that the same phenomena may occur in many in vivo as well as in vitro neural networks.
authors.affiliation: Department of Physics, Korea University, Seoul 136-713, Korea.
authors.forename: June Hoan
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Physics, Korea University, Seoul 136-713, Korea.
authors.forename: Ho Jun
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of Physics, Korea University, Seoul 136-713, Korea.
authors.forename: Cheol Hong
authors.initials: CH
authors.lastname: Min
authors.affiliation: Department of Physics, Korea University, Seoul 136-713, Korea.
authors.forename: Kyoung J
authors.initials: KJ
authors.lastname: Lee
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000465:Algorithms; D000818:Animals; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000502:physiology; D004566:Electrodes; D008959:Models, Neurological; D016571:Neural Networks, Computer; D009474:Neurons / Q000502:physiology*; D062308:Optogenetics; D010507:Periodicity; D010775:Photic Stimulation; D017207:Rats, Sprague-Dawley; D012243:Rhodopsin / Q000235:genetics / Q000378:metabolism; D012815:Signal Processing, Computer-Assisted; D013269:Stochastic Processes
chemical_list: D012243:Rhodopsin