title: Hemolytic Anemia after Aortic Valve Replacement: a Case Report.
abstract: Hemolytic anemia is exceedingly rare and an underestimated complication after aortic valve replacement (AVR).The mechanism responsible for hemolysis most commonly involves a regurgitated flow or jet that related to paravalvar leak or turbulence of subvalvar stenosis. It appears to be independent of its severity as assessed by echocardiography. We present a case of a 24-year-old man with a history of AVR in 10 year ago that developed severe hemolytic anemia due to a mild subvalvar stenosis caused by pannus formation and mild hypertrophic septum. After exclusion of other causes of hemolytic anemia and the lack of clinical and laboratory improvement, the patient underwent redo valve surgery with pannus and subvalvar hypertrophic septum resection. Anemia and heart failure symptoms gradually resolved after surgery.
authors.affiliation: Department of Cardiovascular Surgery, Imam Ali Heart Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
authors.forename: Feridoun
authors.initials: F
authors.lastname: Sabzi
authors.affiliation: Department of Gynecology and Obstetrics, Preventive Gynecology Research center, Imam Hussein Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.
authors.forename: Donya
authors.initials: D
authors.lastname: Khosravi
mesh_terms: D000743:Anemia, Hemolytic / Q000209:etiology*; D001021:Aortic Valve / Q000601:surgery*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D012086:Reoperation; D055815:Young Adult
keywords: Heart failure; Hemolytic anemia; Mitral valve repair; Regurgitated jet