title: Persistent docetaxel-induced supravenous erythematous eruption.
abstract: Taxanes are drugs used to treat many types of cancer, including breast and lung cancer. The most common side effects of these drugs are neutropenia and mucositis. Signs of skin toxicity are observed in about 65% of cases and include alopecia, hypersensitivity reactions, persistent supravenous erythematous eruption, nail changes, scleroderma reactions and others. We report two cases of skin reaction to docetaxel and warn that it is not necessary to interrupt the treatment in these cases.
authors.affiliation: Hospital Naval Marcílio Dias, Rio de Janeiro, RJ, Brazil.
authors.forename: Karina de Almeida Pinto
authors.initials: Kde A
authors.lastname: Fernandes
authors.affiliation: Hospital Naval Marcílio Dias, Rio de Janeiro, RJ, Brazil.
authors.forename: Paulo Antônio Oldani
authors.initials: PA
authors.lastname: Felix
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000077143:Docetaxel; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D004890:Erythema / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D012867:Skin / Q000473:pathology; D043823:Taxoids / Q000009:adverse effects*
chemical_list: D000970:Antineoplastic Agents; D043823:Taxoids; D000077143:Docetaxel