title: 2D mammography, digital breast tomosynthesis, and ultrasound: which should be used for the different breast densities in breast cancer screening?
abstract: OBJECTIVE
  To determine which modalities [2D mammography (2D), digital breast tomosynthesis (DBT), whole breast sonography (WBS)] are optimal for screening depending on breast density.
  
  
  METHODS
  Institutional retrospective cohort study of 2013 screening mammograms (16,789), sorted by modalities and density.
  
  
  RESULTS
  Cancer detection is increased by adding WBS to 2D (P=.02) for the overall study population. Recall rate was lowest with 2D+DBT (10.2%, P<.001) and highest with 2D+DBT+WBS (23.6%, P<.001) for the overall study population as well.
  
  
  CONCLUSIONS
  Women with dense and nondense breasts benefit from reduced recall rate with the addition of DBT; however, this benefit is negated with the addition of WBS.
authors.affiliation: New York-Presbyterian/Weill Cornell, Department of Radiology, 425 East 61st Street, 9th floor, New York, NY 10065.
authors.forename: Anna
authors.initials: A
authors.lastname: Starikov
authors.affiliation: New York-Presbyterian/Weill Cornell, Department of Radiology, 425 East 61st Street, 9th floor, New York, NY 10065.
authors.forename: Michele
authors.initials: M
authors.lastname: Drotman
authors.affiliation: New York-Presbyterian/Weill Cornell, Department of Radiology, 425 East 61st Street, 9th floor, New York, NY 10065.
authors.forename: Keith
authors.initials: K
authors.lastname: Hentel
authors.affiliation: New York-Presbyterian/Weill Cornell, Department of Radiology, 425 East 61st Street, 9th floor, New York, NY 10065.
authors.forename: Janine
authors.initials: J
authors.lastname: Katzen
authors.affiliation: New York-Presbyterian/Weill Cornell, Department of Radiology, 425 East 61st Street, 9th floor, New York, NY 10065.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Min
authors.affiliation: New York-Presbyterian/Weill Cornell, Department of Radiology, 425 East 61st Street, 9th floor, New York, NY 10065. Electronic address: ela9033@med.cornell.edu.
authors.forename: Elizabeth Kagan
authors.initials: EK
authors.lastname: Arleo
mesh_terms: D000328:Adult; D000071060:Breast Density; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D015331:Cohort Studies; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D006801:Humans; D042361:Mammary Glands, Human / Q000002:abnormalities*; D008327:Mammography / Q000379:methods*; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies; D016217:Ultrasonography, Mammary / Q000379:methods*
keywords: 2D mammography; 3D mammography; Breast density; Digital breast tomosynthesis; Keywords