title: Suspect screening of emerging pollutants and their major transformation products in wastewaters treated with fungi by liquid chromatography coupled to a high resolution mass spectrometry.
abstract: A new approach for the screening of 33 pharmaceuticals and 113 of their known transformation products in wastewaters was developed. The methodology is based on the analysis of samples by liquid chromatography coupled to high resolution mass spectrometry (HRMS) followed by data processing using specific software and manual confirmation. A home-made library was built with the transformation products reported in literature for the target pharmaceuticals after treatment with various fungi. The method was applied to the search of these contaminants in 67 samples generated along treatment of wastewaters with white-rot fungus Trametes versicolor. The screening methodology allowed the detection of different transformation products (TPs) generated from degradation of parent compounds after fungal treatment. This approach can be a useful tool for the rapid screening and tentative detection of emerging contaminants during water treatment in both full and batch-scale studies when pure standards are not available.
authors.affiliation: Catalan Institute for Water Research (ICRA), H(2)O Building, Scientific and Technological Park of the University of Girona, 101-E-17003 Girona, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Llorca
authors.affiliation: Catalan Institute for Water Research (ICRA), H(2)O Building, Scientific and Technological Park of the University of Girona, 101-E-17003 Girona, Spain.
authors.forename: Daniel
authors.initials: D
authors.lastname: Lucas
authors.affiliation: Catalan Institute for Water Research (ICRA), H(2)O Building, Scientific and Technological Park of the University of Girona, 101-E-17003 Girona, Spain; Tracer Technology Department, Oil and Gas section, Institute for Energy Technology, P.O. Box 40, NO-2027, Kjeller, Norway.
authors.forename: Laura
authors.initials: L
authors.lastname: Ferrando-Climent
authors.affiliation: Departament d⿿Enginyeria Química, Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Spain.
authors.forename: Marina
authors.initials: M
authors.lastname: Badia-Fabregat
authors.affiliation: Departament d⿿Enginyeria Química, Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Spain.
authors.forename: Carles
authors.initials: C
authors.lastname: Cruz-Morató
authors.affiliation: Catalan Institute for Water Research (ICRA), H(2)O Building, Scientific and Technological Park of the University of Girona, 101-E-17003 Girona, Spain; Water and Soil Quality Research Group Department of Environmental Chemistry, IDAEA-CSIC), Jordi Girona 18-26, 08034 Barcelona, Spain.
authors.forename: Damià
authors.initials: D
authors.lastname: Barceló
authors.affiliation: Catalan Institute for Water Research (ICRA), H(2)O Building, Scientific and Technological Park of the University of Girona, 101-E-17003 Girona, Spain. Electronic address: srodriguez@icra.cat.
authors.forename: Sara
authors.initials: S
authors.lastname: Rodríguez-Mozaz
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D004364:Pharmaceutical Preparations / Q000032:analysis*; D055454:Trametes; D062065:Wastewater / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D004364:Pharmaceutical Preparations; D062065:Wastewater; D014874:Water Pollutants, Chemical
keywords: Bioremediation of wastewaters; LC–HRMS; Post target screening; Suspect screening of transformation products; Trametes versicolor