title: A FRET-based ratiometric two-photon fluorescent probe for dual-channel imaging of nitroxyl in living cells and tissues.
abstract: A FRET-based two-photon fluorescent probe, , which exhibited a fast and high selective ratiometric response to nitroxyl, was first proposed. was successfully applied to two-photon dual-channel imaging of nitroxyl in living cells and tissues with less cross-talk between channels and satisfactory deep-tissue imaging depth.
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
authors.forename: Mengyi
authors.initials: M
authors.lastname: Xiong
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
authors.forename: Hong-wen
authors.initials: HW
authors.lastname: Liu
authors.affiliation: School of Chemistry and Chemical Engineering, Henan, Normal University, Xinxiang, Henan 453007, P. R. China.
authors.forename: Guo-jiang
authors.initials: GJ
authors.lastname: Mao
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
authors.forename: Liyi
authors.initials: L
authors.lastname: Zhou
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Hu
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
authors.forename: Xiao-Bing
authors.initials: XB
authors.lastname: Zhang
authors.affiliation: Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China. xbzhang@hnu.edu.cn tan@chem.ufl.edu.
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
mesh_terms: D002477:Cells / Q000648:ultrastructure*; D003952:Diagnostic Imaging; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D009589:Nitrogen Oxides / Q000032:analysis / Q000737:chemistry*; D017785:Photons
chemical_list: D005456:Fluorescent Dyes; D009589:Nitrogen Oxides; C039900:nitroxyl