title: A Metal-Organic Framework/DNA Hybrid System as a Novel Fluorescent Biosensor for Mercury(II) Ion Detection.
abstract: Mercury(II) ions have emerged as a widespread environmental hazard in recent decades. Despite different kinds of detection methods reported to sense Hg(2+) , it still remains a challenging task to develop new sensing molecules to replenish the fluorescence-based apparatus for Hg(2+) detection. This communication demonstrates a novel fluorescent sensor using UiO-66-NH2 and a T-rich FAM-labeled ssDNA as a hybrid system to detect Hg(2+) sensitively and selectively. To the best of our knowledge, it has rarely been reported that a MOF is utilized as the biosensing platform for Hg(2+) assay.
authors.affiliation: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022 (P. R. China).|University of Chinese Academy of Sciences, Beijing, 100049 (P. R. China).
authors.forename: Lan-Lan
authors.initials: LL
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022 (P. R. China).|University of Chinese Academy of Sciences, Beijing, 100049 (P. R. China).
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022 (P. R. China).|University of Chinese Academy of Sciences, Beijing, 100049 (P. R. China).
authors.forename: Shu-Na
authors.initials: SN
authors.lastname: Zhao
authors.affiliation: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022 (P. R. China).|University of Chinese Academy of Sciences, Beijing, 100049 (P. R. China).
authors.forename: Xing
authors.initials: X
authors.lastname: Meng
authors.affiliation: School of Petroleum and Chemical Engineering, Dalian University of Technology, 2 Dagong Road, Liaodongwan New District, Panjin 124221, Liaoning (P. R. China).
authors.forename: Xue-Zhi
authors.initials: XZ
authors.lastname: Song
authors.affiliation: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022 (P. R. China).
authors.forename: Jing
authors.initials: J
authors.lastname: Feng
authors.affiliation: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022 (P. R. China). songsy@ciac.ac.cn.
authors.forename: Shu-Yan
authors.initials: SY
authors.lastname: Song
authors.affiliation: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022 (P. R. China). hongjie@ciac.ac.cn.
authors.forename: Hong-Jie
authors.initials: HJ
authors.lastname: Zhang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry*; D007477:Ions / Q000737:chemistry*; D057230:Limit of Detection; D008628:Mercury / Q000032:analysis* / Q000737:chemistry*
chemical_list: D004277:DNA, Single-Stranded; D007477:Ions; D004247:DNA; D008628:Mercury
keywords: DNA; fluorescence; host-guest systems; mercury; metal-organic frameworks