title: Rescuers' physical fatigue with different chest compression to ventilation methods during simulated infant cardiopulmonary resuscitation.
abstract: OBJECTIVE
  To assess development of objective, subjective and indirect measures of fatigue during simulated infant cardiopulmonary resuscitation (CPR) with two different methods.
  
  
  METHODS
  Using a neonatal manikin, 17 subject-pairs were randomized in a crossover design to provide 5-min CPR with a 3:1 chest compression (CC) to ventilation (C:V) ratio and continuous CCs at a rate of 120 min(-1) with asynchronous ventilations (CCaV-120). We measured participants' changes in heart rate (HR) and mean arterial pressure (MAP); perceived level of fatigue on a validated Likert scale; and manikin CC measures.
  
  
  RESULTS
  CCaV-120 compared with a 3:1 C:V ratio resulted in a change during 5-min of CPR in HR 49 versus 40 bpm (p = 0.01), and MAP 1.7 versus -2.8 mmHg (p = 0.03); fatigue rated on a Likert scale 12.9 versus 11.4 (p = 0.2); and a significant decay in CC depth after 90 s (p = 0.03).
  
  
  CONCLUSIONS
  The results indicate a trend toward more fatigue during simulated CPR in CCaV-120 compared to the recommended 3:1 C:V CPR. These results support current guidelines.
authors.affiliation: a Department of Pediatric and Adolescent Medicine , Akershus University Hospital , Lørenskog , Norway and.|b Akershus Faculty Division, Institute of Clinical Medicine, University of Oslo , Lørenskog , Norway.
authors.forename: Anne Marthe
authors.initials: AM
authors.lastname: Boldingh
authors.affiliation: a Department of Pediatric and Adolescent Medicine , Akershus University Hospital , Lørenskog , Norway and.
authors.forename: Thomas Hagen
authors.initials: TH
authors.lastname: Jensen
authors.affiliation: a Department of Pediatric and Adolescent Medicine , Akershus University Hospital , Lørenskog , Norway and.
authors.forename: Ane Torvik
authors.initials: AT
authors.lastname: Bjørbekk
authors.affiliation: a Department of Pediatric and Adolescent Medicine , Akershus University Hospital , Lørenskog , Norway and.
authors.forename: Anne Lee
authors.initials: AL
authors.lastname: Solevåg
authors.affiliation: a Department of Pediatric and Adolescent Medicine , Akershus University Hospital , Lørenskog , Norway and.|b Akershus Faculty Division, Institute of Clinical Medicine, University of Oslo , Lørenskog , Norway.
authors.forename: Britt
authors.initials: B
authors.lastname: Nakstad
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D018592:Cross-Over Studies; D005221:Fatigue / Q000503:physiopathology*; D006282:Health Personnel / Q000706:statistics & numerical data; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008348:Manikins; D011897:Random Allocation; D000066908:Simulation Training; D013997:Time Factors
keywords: Manikin; neonatology; quality