title: Erectile Dysfunction Is Positively Correlated with Mean Platelet Volume and Platelet Count, but Not with Eosinophil Count in Peripheral Blood.
abstract: OBJECTIVE
  Increased eosinophil count (EC), mean platelet volume (MPV), and platelet count (PC) are important in vascular disorders which are main factors resulting in endothelial dysfunction. We aimed to investigate the association between MPV, and EC, with erectile dysfunction (ED).
  
  
  METHODS
  Two hundred thirty participants (130 patients with ED, and 100 healthy controls) were enrolled in this study. A detailed psychosexual history obtained, and physical, and laboratory examination were performed. International Index of Erectile Function (IIEF)-5 questionnaire was used to evaluate the erectile status objectively. IIEF-5 score was applied to all patients, and IIEF-5 score under 22 was considered as ED. The MPV, PC, and EC were compared between the two groups.
  
  
  RESULTS
  The mean age of the patients with ED and control group was 55.62 ± 8.90 years and 54.19 ± 4.10 years, respectively. MPV and PC levels were significantly higher in ED group (8.51± 1.00 fL and 8.16 ± 0.94 fL; 244.59 ± 57.3 cells/µL and 230.17 ± 48.44 cells/µL, respectively (P < .05). EC and white blood cell count were not significantly different between study and control groups.
  
  
  CONCLUSIONS
  In our study a relationship was found between elevated MPV, and PC with ED. MPV and PC may be used as a biomarker in patients with ED.
authors.affiliation: Department of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Otunctemur
authors.affiliation: Department of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey.
authors.forename: Muammer
authors.initials: M
authors.lastname: Bozkurt
authors.affiliation: Department of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Besiroglu
authors.affiliation: Department of Urology, Istanbul Medipol University, Istanbul, Turkey.
authors.forename: Emre Can
authors.initials: EC
authors.lastname: Polat
authors.affiliation: Department of Urology, Derince Training and Research Hospital, Kocaeli, Turkey.
authors.forename: Levent
authors.initials: L
authors.lastname: Ozcan
authors.affiliation: Department of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey.
authors.forename: Emin
authors.initials: E
authors.lastname: Ozbek
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D004804:Eosinophils; D007172:Erectile Dysfunction / Q000097:blood*; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D010976:Platelet Count; D011446:Prospective Studies; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D015415:Biomarkers