title: Surgical treatment for a paraplegic patient induced by congenital factor X deficiency.
abstract: Congenital factor X (FX) deficiency is a rare disease which usually leads to coagulation disorders. We reported a case of paraplegic patient induced by traumatic spinal epidural hematoma which was associated with congenital FX deficiency. The treatments of this patient included elevating FX activity (FX: C) by adding fresh-frozen plasma (FFP) or prothrombin complex concentration (PCC) to improve his coagulation function, and doing operation to remove his spinal hematoma. Symptoms started to resolve after operation. Besides, we found one of his elder brother had the same disease as the patient himself via family follow-up. They can survive because their FX: C are relatively high enough to keep them away from fatal bleeding.
authors.affiliation: Department of Orthopedic Trauma, Peking University People Trauma Beijing 100044, P. R. China.
authors.forename: Weicheng
authors.initials: W
authors.lastname: Lin
authors.affiliation: Department of Orthopedic Trauma, Peking University People Trauma Beijing 100044, P. R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Department of Orthopedic Trauma, Peking University People Trauma Beijing 100044, P. R. China.
authors.forename: Tianbing
authors.initials: T
authors.lastname: Wang
authors.affiliation: Department of Orthopedic Trauma, Peking University People Trauma Beijing 100044, P. R. China.
authors.forename: Peixun
authors.initials: P
authors.lastname: Zhang
keywords: Congenital factor X deficiency; spinal epidural hematoma