title: Vaccine candidates for malaria: what's new?
abstract: Although it is more than a decade since the parasite genome information was obtained, standardized novel genome-wide selection/prioritization strategies for candidacy of malaria vaccine antigens are still sought. In the quest to systematically identify candidates, it is impossible to overemphasize the usefulness of wheat germ cell-free technology in expressing quality proteins for the post-genome vaccine candidate discovery.
authors.affiliation: a Division of Malaria Research, Proteo-Science Center , Ehime University , Matsuyama , Ehime 790-8577 , Japan.
authors.forename: Eizo
authors.initials: E
authors.lastname: Takashima
authors.affiliation: a Division of Malaria Research, Proteo-Science Center , Ehime University , Matsuyama , Ehime 790-8577 , Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Morita
authors.affiliation: a Division of Malaria Research, Proteo-Science Center , Ehime University , Matsuyama , Ehime 790-8577 , Japan.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Tsuboi
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000235:genetics / Q000276:immunology; D002474:Cell-Free System; D055808:Drug Discovery / Q000379:methods* / Q000639:trends; D018503:Genome, Protozoan; D006801:Humans; D008288:Malaria / Q000453:epidemiology* / Q000517:prevention & control*; D017780:Malaria Vaccines / Q000276:immunology* / Q000302:isolation & purification*; D010961:Plasmodium / Q000235:genetics / Q000276:immunology; D014176:Protein Biosynthesis
chemical_list: D000953:Antigens, Protozoan; D017780:Malaria Vaccines
keywords: Plasmodium falciparum; RTSS/AS01; antibody profiling approach; malaria; post-genome; reverse vaccinology; subunit vaccine; vaccine candidate discovery; whole-parasite vaccine