title: A rare combination of amniotic constriction band with osteogenesis imperfecta.
abstract: Amniotic constriction bands and osteogenesis imperfecta are disorders arising from a collagen defect. We report a rare association of amniotic bands with osteogenesis imperfecta in a child. The child was born with multiple amniotic bands involving the right leg, both hands and both feet. Multiple fractures of long bones of lower limbs occurred in childhood due to trivial trauma. Deformities of the femur and tibia due to malunion with osteopenia and blue sclerae were present. The patient was treated with z plasty of constriction band of the right tibia and bisphosphonate for osteogenesis imperfecta. This rare association of both collagen diseases may provide further insight for the pathogenesis of these diseases.
authors.affiliation: Department of Obstetrics and Gynaecology, Melaka Manipal Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Krupa Hitesh
authors.initials: KH
authors.lastname: Shah
authors.affiliation: Department of Orthopaedics, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Hitesh
authors.initials: H
authors.lastname: Shah
mesh_terms: D019386:Alendronate / Q000627:therapeutic use; D000652:Amniotic Band Syndrome / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D001851:Bone Diseases, Metabolic / Q000150:complications / Q000473:pathology; D002675:Child, Preschool; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D050723:Fractures, Bone / Q000209:etiology / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010013:Osteogenesis Imperfecta / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D050071:Bone Density Conservation Agents; D019386:Alendronate