title: Long-term cognitive sequelae in a case of Wernicke's encephalopathy after allogeneic stem cell transplantation.
abstract: We describe the case of a non-alcoholic patient with chronic myeloid leukemia who developed iatrogenic Wernicke's encephalopathy (WE) following stem cell transplantation. Four years after the WE acute event, the patient's cognitive profile was mainly characterized by moderate memory impairment, and functional and daily-living difficulties. Our report sustains the hypothesis that a iatrogenic form of WE may produce long-term cognitive sequelae even when thiamine therapy is administered in the acute phase until the resolution of the neurological signs.
authors.affiliation: a Unit of Neurology , Florence Health Authority , Florence , Italy.|b Department of Psychology , University of Milano-Bicocca , Milan , Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Giovannelli
authors.affiliation: c Cardinal Ferrari Rehabilitation Center , Fontanellato , Italy.
authors.forename: Benedetta
authors.initials: B
authors.lastname: Basagni
authors.affiliation: d Section of Hematology, Department of Surgical and Medical Sciences , University of Modena and Reggio Emilia , Modena , Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Potenza
authors.affiliation: c Cardinal Ferrari Rehabilitation Center , Fontanellato , Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Foschi
authors.affiliation: c Cardinal Ferrari Rehabilitation Center , Fontanellato , Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: De Tanti
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000209:etiology*; D006801:Humans; D007951:Leukemia, Myeloid / Q000209:etiology; D008137:Longitudinal Studies; D008297:Male; D009483:Neuropsychological Tests; D011183:Postoperative Complications / Q000503:physiopathology; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D014184:Transplantation, Homologous; D014899:Wernicke Encephalopathy / Q000150:complications* / Q000601:surgery*
keywords: Wernicke’s encephalopathy; cognitive profile; stem cell transplantation