title: Metastasis to the Glans Penis: An Unusual Site of Rectal Cancer Recurrence.
abstract: Secondary malignancy of the penis is a rare clinical condition, often associated with disseminated genitourinary malignancies. The prognosis is poor and the treatment options include penectomy, local surgical excision, radiation therapy, chemotherapy and supportive therapy. Neither of these therapeutic options lead to superior treatment outcomes in the literature. The authors report the case of a 66 year-old man with a metastasis to the glans penis from a rectal adenocarcinoma, diagnosed two years after radical treatment for primary disease. The patient underwent palliative treatment with radiotherapy and chemotherapy, remaining asymptomatic and disease-free at one year follow-up. Close follow-up of patients with history of rectal adenocarcinoma is very important. Radiochemotherapy is a feasible and effective therapeutic option for penile metastasis, addressing both disease control and symptomatic improvement.
authors.affiliation: Serviço de Radioterapia. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Nunes
authors.affiliation: Serviço de Oncologia Médica. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.
authors.forename: Margarida
authors.initials: M
authors.lastname: Matias
authors.affiliation: Serviço de Anatomia Patológica. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.
authors.forename: António
authors.initials: A
authors.lastname: Alves
authors.affiliation: Serviço de Radioterapia. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.
authors.forename: Marília
authors.initials: M
authors.lastname: Jorge
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D010412:Penile Neoplasms / Q000175:diagnosis / Q000556:secondary*; D010413:Penis; D012004:Rectal Neoplasms / Q000473:pathology*