title: Synthesis, Characterization, and Anti-Inflammatory Activity of Newer Quinazolinone Analogs.
abstract: A series of 3-[2'-(Substitutedbenzylideneamino)phenyl]-2-methyl-6-substituted quinazolin-4-ones (5-10), 3-[2'-(3(″)-chloro-2(″)-oxo-4(″)-substitutedphenylazetidin-1(″)-yl)phenyl]-2-methyl-6-substitutedquinazolin-4-ones (11-16), and 3-[2'-(2(″)-substitutedphenyl-4(″)-oxo-1(″),3(″)-thiazolidin-3(″)-yl)phentl]-2-methyl-6-substitutedquinazolin-4-ones (17-22) have been synthesized in the present study. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR, (1)H NMR, and mass spectral data. All the newly synthesized compounds were screened for anti-inflammatory and analgesic activities.
authors.affiliation: Medicinal Chemistry Division, Department of Pharmacology, L.L.R.M. Medical College, Meerut 250002, India ; Jubilant Chemsys Ltd. R & D B-34, Sector 58, Noida 201301, India.
authors.forename: Chatrasal Singh
authors.initials: CS
authors.lastname: Rajput
authors.affiliation: Medicinal Chemistry Division, Department of Pharmacology, L.L.R.M. Medical College, Meerut 250002, India.
authors.forename: Shiwani
authors.initials: S
authors.lastname: Singhal