title: Frequency of preterm delivery in proteinuric verses non proteinuric pregnancy induced hypertension.
abstract: OBJECTIVE
  To compare the frequency of preterm labour associated with gestational proteinuric hypertension versus gestational non-proteinuric hypertension.
  
  
  METHODS
  The prospective cohort study was conducted at the Department of Obstetrics & Gynaecology, Dow University of Health Sciences and Civil Hospital Karachi, from April 1 to September 30, 2012, and comprised primigravidas of more than or equal to 20th weeks of gestation having blood pressure >140/90 mm Hg. Those with gestational hypertension with proteinuria represented the exposed group, while the non-exposed group had primigravidas with gestational hypertension without proteinuria. SPSS 10 was used to analyse data.
  
  
  RESULTS
  There were 112 subjects, with 56(50%) in each of the two groups. Mean maternal age in exposed group was 28.3±4.49 years and in the non-exposed group 26.08±0.04 years. Mean gestational age in the exposed group was 36.89±4.04 weeks and in the non-exposed group 37.75±3.428 weeks. Women with gestational hypertension with proteinuria were more likely to deliver preterm infants compared to women with gestational hypertension without proteinuria (p=0.009).
  
  
  CONCLUSIONS
  Gestational proteinuric hypertension increased the risk of preterm labour, therefore vigilant monitoring of gestational proteinuric hypertension is important.
authors.affiliation: Department of Obstetrics & Gynecology, Unit II, Dow Medical College & Civil Hospital, Karachi.
authors.forename: Saima
authors.initials: S
authors.lastname: Sheikh
authors.affiliation: Department of Obstetrics & Gynecology, Unit II, Dow University of Health Sciences, Karachi.
authors.forename: Gulfishan
authors.initials: G
authors.lastname: Haq
authors.affiliation: Department of Obstetrics & Gynecology, Unit II, Dow University of Health Sciences, Karachi.
authors.forename: Sarah
authors.initials: S
authors.lastname: Kazi
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000209:etiology*; D010154:Pakistan; D011247:Pregnancy; D047928:Premature Birth / Q000453:epidemiology*; D011446:Prospective Studies; D011507:Proteinuria / Q000150:complications*; D055815:Young Adult
keywords: Proteinuria, Gestational hypertension, Pregnancy-induced hypertension, Preterm labour.