title: Legal Barriers to Adolescent Participation in Research About HIV and Other Sexually Transmitted Infections.
abstract: Whether adolescents can participate in clinical trials of pharmacologic therapies for HIV prevention, such as preexposure prophylaxis, without parental permission hinges on state minor consent laws. Very few of these laws explicitly authorize adolescents to consent to preventive services for HIV and other sexually transmitted infections. Unclear state laws may lead to research cessation. We have summarized legal, ethical, and policy considerations related to adolescents' participation in HIV and sexually transmitted infection prevention research in the United States, and we have explored strategies for facilitating adolescents' access.
authors.affiliation: Quianta L. Moore, Amy L. McGuire, and Mary A. Majumder are with the Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX. Quianta L. Moore is also with the Baker Institute for Public Policy, Rice University, Houston. Mary E. Paul is with the Department of Pediatrics, Retrovirology, Baylor College of Medicine.
authors.forename: Quianta L
authors.initials: QL
authors.lastname: Moore
authors.affiliation: Quianta L. Moore, Amy L. McGuire, and Mary A. Majumder are with the Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX. Quianta L. Moore is also with the Baker Institute for Public Policy, Rice University, Houston. Mary E. Paul is with the Department of Pediatrics, Retrovirology, Baylor College of Medicine.
authors.forename: Mary E
authors.initials: ME
authors.lastname: Paul
authors.affiliation: Quianta L. Moore, Amy L. McGuire, and Mary A. Majumder are with the Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX. Quianta L. Moore is also with the Baker Institute for Public Policy, Rice University, Houston. Mary E. Paul is with the Department of Pediatrics, Retrovirology, Baylor College of Medicine.
authors.forename: Amy L
authors.initials: AL
authors.lastname: McGuire
authors.affiliation: Quianta L. Moore, Amy L. McGuire, and Mary A. Majumder are with the Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX. Quianta L. Moore is also with the Baker Institute for Public Policy, Rice University, Houston. Mary E. Paul is with the Department of Pediatrics, Retrovirology, Baylor College of Medicine.
authors.forename: Mary A
authors.initials: MA
authors.lastname: Majumder
mesh_terms: D000293:Adolescent; D018890:Chemoprevention / Q000941:ethics / Q000379:methods; D002986:Clinical Trials as Topic / Q000941:ethics / Q000331:legislation & jurisprudence*; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control*; D006291:Health Policy; D006801:Humans; D033242:Minors / Q000331:legislation & jurisprudence*; D033282:Parental Consent / Q000941:ethics / Q000331:legislation & jurisprudence*; D035842:Research Subjects / Q000331:legislation & jurisprudence*; D012749:Sexually Transmitted Diseases / Q000453:epidemiology / Q000517:prevention & control; D013219:State Government; D014481:United States / Q000453:epidemiology