title: Gorham-Stout disease of the proximal fibula treated with radiotherapy and zoledronic acid.
abstract: Gorham-Stout disease is a rare disease characterized by anarchic lymphovascular proliferation causing resorption of bone sometimes leading to disastrous complications. Bone tissue is progressively replaced by angiomatic and lymphangiomatic tissue and finally by fibrous tissue. This disease is known to be ubiquitous and of complex etiology. We present a case of Gorham-Stout disease of the proximal fibula invading the proximal tibia and soft tissues of the popliteal space that was successfully treated with radiotherapy and zoledronic acid.
authors.affiliation: Department of Orthopaedic Surgery, Institut Jules. Bordet, Université Libre de Bruxelles, Brussels, Belgium.
authors.forename: V V
authors.initials: VV
authors.lastname: Yerganyan
authors.affiliation: Department of Medicine, CHU Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
authors.forename: J J
authors.initials: JJ
authors.lastname: Body
authors.affiliation: Departement of Anatomopathology, Institut Jules. Bordet, Université Libre de Bruxelles, Brussels, Belgium.
authors.forename: N
authors.initials: N
authors.lastname: De Saint Aubain
authors.affiliation: Department of Orthopaedic Surgery, Institut Jules. Bordet, Université Libre de Bruxelles, Brussels, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Gebhart
keywords: Bisphosphonates; Bone radiotherapy; Bone resorption; Gorham–Stout disease; Pseudotumor of bone