title: Leproma Presenting as a Nasal Cavity Mass.
abstract: Leprosy is a rare disease and unfamiliar to many people. A 55-year-old woman was presented to our hospital complaining of nasal obstruction and anosmia. Nasal endoscopic examination revealed reddish-colored exophytic, nonulcerative masses in both nasal cavities. The authors performed endoscopic sinus surgery which involved endoscopic mass removal and synechiolysis. A biopsy sample stained with acid-fast stain and a rapid silver stain showed numerous filamentous organisms infiltrating macrophages, consistent with lepromatous leprosy. The patient was treated with a triple drug regimen of rifampin and dapsone with clofazimine. Herein, the authors present a case of nasal leproma as a differential diagnosis of a nasal cavity mass.
authors.affiliation: *Department of Otolaryngology-Head and Neck Surgery †Research Institute of Clinical Medicine, Chonbuk National University Hospital and Chonbuk National University ‡Department of Plastic and Reconstructive Surgery, Chonbuk National University, Jeonju, South Korea.
authors.forename: Jong Seung
authors.initials: JS
authors.lastname: Kim
authors.forename: Sam Hyun
authors.initials: SH
authors.lastname: Kwon
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Shin
mesh_terms: D001706:Biopsy / Q000379:methods; D002991:Clofazimine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004724:Endoscopy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007917:Leprostatic Agents / Q000627:therapeutic use; D015440:Leprosy, Lepromatous / Q000175:diagnosis*; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology*; D015508:Nasal Obstruction / Q000175:diagnosis*; D000857:Olfaction Disorders / Q000175:diagnosis; D012293:Rifampin / Q000627:therapeutic use; D000267:Tissue Adhesions / Q000175:diagnosis
chemical_list: D007917:Leprostatic Agents; D003622:Dapsone; D002991:Clofazimine; D012293:Rifampin