title: Phylogenetic relationships of Iranian infectious hematopoietic necrosis virus of rainbow trout (Oncorhynchus mykiss) based on the glycoprotein gene.
abstract: Infectious hematopoietic necrosis virus (IHNV), a member of family Rhabdoviridae and genus Novirhabdoviridae, causes a highly lethal disease of salmon and trout. In Iran IHNV was first detected in 2001 on farms rearing rainbow trout (Oncorhynchus mykiss). To evaluate the genetic relationships of IHNV from northern and western Iran, the sequences of a 651-nt region of the glycoprotein gene were determined for two Iranian isolates. These sequences were analyzed to evaluate their genetic relatedness to worldwide isolates representing the five known genogroups of IHNV. Iranian isolates were most closely related to European isolates within the genogroup E rather than those of North American genogroups U, M and L, or the Asian genogroup J. It appears that Iranian IHNV was most likely introduced to Iran from a source in Europe by the movement of contaminated fish eggs.
authors.affiliation: Department of Aquatic Animal Health and Diseases, Iranian Fisheries Research Center, Tehran, Iran.
authors.forename: Milad
authors.initials: M
authors.lastname: Adel
authors.affiliation: Department of Aquatic Animal Health and Diseases, Iranian Veterinary Organization, Sari, Iran.
authors.forename: Alireza Babaalian
authors.initials: AB
authors.lastname: Amiri
authors.affiliation: Center of Biotechnology and Biology Research, Chamran University, Ahvaz, Iran. dadar.m77@gmail.com.
authors.forename: Maryam
authors.initials: M
authors.lastname: Dadar
authors.affiliation: School of Aquatic and Fishery Sciences, University of Washington, Seattle, WA, 98105, USA.
authors.forename: Rachel
authors.initials: R
authors.lastname: Breyta
authors.affiliation: U.S. Geological Survey, Western Fisheries Research Center, Seattle, WA, 98115, USA.
authors.forename: Gael
authors.initials: G
authors.lastname: Kurath
authors.affiliation: Department of Aquatic Animal Health and Diseases, Iranian Veterinary Organization, Sari, Iran.
authors.forename: Bahram
authors.initials: B
authors.lastname: Laktarashi
authors.affiliation: Department of Aquatic Animal Health and Diseases, Iranian Veterinary Organization, Tehran, Iran.
authors.forename: Amrolah
authors.initials: A
authors.lastname: Ghajari
mesh_terms: D000818:Animals; D016000:Cluster Analysis; D005393:Fish Diseases / Q000821:virology*; D014644:Genetic Variation; D005838:Genotype; D006023:Glycoproteins / Q000235:genetics*; D029142:Infectious hematopoietic necrosis virus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D007492:Iran; D008969:Molecular Sequence Data; D017686:Oncorhynchus mykiss / Q000821:virology*; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D018353:Rhabdoviridae Infections / Q000821:virology*; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D014764:Viral Proteins / Q000235:genetics
chemical_list: D006023:Glycoproteins; D012367:RNA, Viral; D014764:Viral Proteins
keywords: Fish virus phylogeny; IHNV; IHNV genogroup E; IHNV phylogenetics; Infectious hematopoietic necrosis virus; Iran fish disease; Iran fish virus; Iran trout culture; Iranian virus strains