title: Consensus Paper: Probing Homeostatic Plasticity of Human Cortex With Non-invasive Transcranial Brain Stimulation.
abstract: Homeostatic plasticity is thought to stabilize neural activity around a set point within a physiologically reasonable dynamic range. Over the last ten years, a wide range of non-invasive transcranial brain stimulation (NTBS) techniques have been used to probe homeostatic control of cortical plasticity in the intact human brain. Here, we review different NTBS approaches to study homeostatic plasticity on a systems level and relate the findings to both, physiological evidence from in vitro studies and to a theoretical framework of homeostatic function. We highlight differences between homeostatic and other non-homeostatic forms of plasticity and we examine the contribution of sleep in restoring synaptic homeostasis. Finally, we discuss the growing number of studies showing that abnormal homeostatic plasticity may be associated to a range of neuropsychiatric diseases.
authors.forename: Anke
authors.initials: A
authors.lastname: Karabanov
authors.forename: Ulf
authors.initials: U
authors.lastname: Ziemann
authors.forename: Masashi
authors.initials: M
authors.lastname: Hamada
authors.forename: Mark S
authors.initials: MS
authors.lastname: George
authors.forename: Angelo
authors.initials: A
authors.lastname: Quartarone
authors.forename: Joseph
authors.initials: J
authors.lastname: Classen
authors.forename: Marcello
authors.initials: M
authors.lastname: Massimini
authors.forename: John
authors.initials: J
authors.lastname: Rothwell
authors.forename: Hartwig Roman
authors.initials: HR
authors.lastname: Siebner
mesh_terms: D002540:Cerebral Cortex / Q000502:physiology*; D006706:Homeostasis; D006801:Humans; D009473:Neuronal Plasticity; D065908:Transcranial Direct Current Stimulation; D050781:Transcranial Magnetic Stimulation