title: [Hepatic encephalopathy].
abstract: Hepatic encephalopathy is a severe complication of liver cirrhosis and is an important therapeutic challenge, with a social and economic issue. If, now, the pathophysiology is not totally understood (main role of ammonia, but a better understanding of cerebral mechanisms), the clinical presentation is well-known. Some treatments are useful (disaccharides, treatment of the trigger) but their efficiency is limited. Nevertheless, the emergence of new treatments, such as non-absorbable antibiotics (rifaximin essentially), is an interesting therapeutic tool.
authors.affiliation: CHU de Limoges, service d'hépato-gastroentérologie, 2, avenue Luther-King, 87042 Limoges, France.
authors.forename: Jérémie
authors.initials: J
authors.lastname: Jacques
authors.affiliation: CHU de Limoges, service d'hépato-gastroentérologie, 2, avenue Luther-King, 87042 Limoges, France. Electronic address: paul.carrier@chu-limoges.fr.
authors.forename: Paul
authors.initials: P
authors.lastname: Carrier
authors.affiliation: CHU de Limoges, service d'hépato-gastroentérologie, 2, avenue Luther-King, 87042 Limoges, France.
authors.forename: Marilyne
authors.initials: M
authors.lastname: Debette-Gratien
authors.affiliation: AP-HP, hôpital Paul-Brousse, université Paris-Sud, Hepatinov, centre hépato-biliaire, Inserm UMR-S 785, avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
authors.forename: Rodolphe
authors.initials: R
authors.lastname: Sobesky
authors.affiliation: CHU de Limoges, service d'hépato-gastroentérologie, 2, avenue Luther-King, 87042 Limoges, France; Université de Limoges, faculté de médecine, Inserm UMR 1092, 2, rue du Docteur-Marcland, 87025 Limoges cedex, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Loustaud-Ratti
mesh_terms: D006501:Hepatic Encephalopathy / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006801:Humans