title: Salmonella newport causing osteomyelitis in a patient with diabetes.
abstract: Salmonella is a foodborne pathogen that commonly causes intestinal symptoms. Bacteraemia and extraintestinal infections have been documented within the literature, and are more frequently associated with immunodeficiency and general debilitation. We discuss the case of a previously well 36-year-old man who presented with a septic knee and new-onset diabetes. Imaging confirmed osteomyelitis and a Brodie's abscess, with blood and tissue cultures revealing the isolate Salmonella enterica newport. He denied any previous gastrointestinal symptoms, recent travel, change in usual dietary habit or symptoms of diabetes. So far there have only been three reported cases of S. newport causing osteomyelitis. We discuss the incidence of Salmonella infections, including extraintestinal symptoms, its relation to immunodeficiency and the disease burden of S. newport.
authors.affiliation: The Heart of England NHS Trust, Birmingham, UK.
authors.forename: Natasha
authors.initials: N
authors.lastname: Weston
authors.affiliation: Department of Infectious Diseases and Tropical Medicine, Birmingham Heartlands Hospital, Heart of England NHS Hospital Trust, Birmingham, UK.
authors.forename: Ed
authors.initials: E
authors.lastname: Moran
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016883:Diabetic Ketoacidosis / Q000382:microbiology*; D006801:Humans; D007719:Knee Joint / Q000382:microbiology* / Q000473:pathology; D008297:Male; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D010146:Pain / Q000382:microbiology* / Q000473:pathology; D010400:Penicillin G / Q000627:therapeutic use; D012475:Salmonella / Q000302:isolation & purification*; D012480:Salmonella Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D013045:Species Specificity; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000658:Amoxicillin; D010400:Penicillin G