title: Spectral-Domain Optical Coherence Tomography of Polypoidal Choroidal Vasculopathy Associated With Benign Choroidal Nevus.
abstract: Two cases of polypoidal choroidal vasculopathy (PCV) complicating benign choroidal nevus and their tomographic features at spectral-domain optical coherence tomography (SD-OCT) are reported. Two eyes with choroidal nevus and associated subretinal fluid underwent complete ophthalmological examination, SD-OCT, fundus fluorescein angiography, and indocyanine green angiography (ICGA). SD-OCT and ICGA confirmed the diagnosis of PCV in both cases. Ophthalmologists should be aware of this rare combination between choroidal nevus and PCV. If a choroidal nevus presents with subretinal fluid, this does not always herald malignant transformation, and PCV should be ruled out so that the correct treatment can be planned.
authors.forename: Gabriella
authors.initials: G
authors.lastname: De Salvo
authors.forename: Sara
authors.initials: S
authors.lastname: Vaz-Pereira
authors.forename: Kulwant S
authors.initials: KS
authors.lastname: Sehmi
authors.forename: Richard M
authors.initials: RM
authors.lastname: Andrews
authors.forename: Mandeep S
authors.initials: MS
authors.lastname: Sagoo
mesh_terms: D000368:Aged; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D002199:Capillary Permeability; D002830:Choroid Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D020256:Choroidal Neovascularization / Q000175:diagnosis* / Q000188:drug therapy; D005122:Exudates and Transudates; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D009508:Nevus, Pigmented / Q000175:diagnosis* / Q000188:drug therapy; D010778:Photochemotherapy; D011127:Polyps / Q000175:diagnosis* / Q000188:drug therapy; D000069579:Ranibizumab / Q000627:therapeutic use; D012163:Retinal Detachment / Q000175:diagnosis; D055213:Retinal Pigment Epithelium / Q000473:pathology; D041623:Tomography, Optical Coherence; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors; D014792:Visual Acuity
chemical_list: D020533:Angiogenesis Inhibitors; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D000069579:Ranibizumab