title: Cancer Cells Hijack Gluconeogenic Enzymes to Fuel Cell Growth.
abstract: In this issue and the October 15th issue of Molecular Cell, studies by Montal et al. (2015) and Vincent et al. (2015) report that certain types of cancer cells utilize the gluconeogenic enzymes phosphoenolpyruvate carboxykinase (PEPCK) and phosphoenolpyruvate carboxykinase 2 (PCK2) to reprogram anabolic metabolism and support cell growth.
authors.affiliation: Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Balsa-Martinez
authors.affiliation: Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: pere_puigserver@dfci.harvard.edu.
authors.forename: Pere
authors.initials: P
authors.lastname: Puigserver
mesh_terms: D000818:Animals; D002289:Carcinoma, Non-Small-Cell Lung / Q000378:metabolism*; D015972:Gene Expression Regulation, Neoplastic; D005943:Gluconeogenesis / Q000235:genetics*; D006801:Humans; D008175:Lung Neoplasms / Q000378:metabolism*; D009369:Neoplasms / Q000378:metabolism*; D019764:Phosphoenolpyruvate Carboxykinase (ATP) / Q000378:metabolism*
chemical_list: D019764:Phosphoenolpyruvate Carboxykinase (ATP)