title: Emerging Technologies and their Applications in Lipid Compartment Measurement.
abstract: Non-Communicable diseases (NCDs), including obesity, are emerging as the major health concern of the 21st century. Excess adiposity and related NCD metabolic disturbances have stimulated development of new lipid compartment measurement technologies to help us to understand cellular energy exchange, to refine phenotypes, and to develop predictive markers of adverse clinical outcomes. Recent advances now allow quantification of multiple intracellular lipid and adipose tissue compartments that can be evaluated across the human lifespan. With magnetic resonance methods leading the way, newer approaches will give molecular structural and metabolic information beyond the laboratory in real-world settings. The union between these new technologies and the growing NCD population is creating an exciting interface in advancing our understanding of chronic disease mechanisms.
authors.affiliation: Pennington Biomedical Research Center, Louisiana State University (LSU) System, 6400 Perkins Road, Baton Rouge, LA 70808, USA. Electronic address: Steven.Heymsfield@pbrc.edu.
authors.forename: Steven B
authors.initials: SB
authors.lastname: Heymsfield
authors.affiliation: Phoenix Children's Hospital, Department of Radiology, 1919 East Thomas Road, Phoenix, AZ 85016, USA.
authors.forename: Houchun Harry
authors.initials: HH
authors.lastname: Hu
authors.affiliation: New York Obesity Research Center, Department of Pediatrics and Institute of Human Nutrition, Columbia University, New York, NY 10032, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Shen
authors.affiliation: Pennington Biomedical Research Center, Louisiana State University (LSU) System, 6400 Perkins Road, Baton Rouge, LA 70808, USA.
authors.forename: Owen
authors.initials: O
authors.lastname: Carmichael
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D050154:Adiposity / Q000502:physiology*; D001823:Body Composition / Q000502:physiology; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009765:Obesity / Q000378:metabolism*
chemical_list: D008055:Lipids
keywords: adiposity; body composition; imaging; metabolism; obesity