title: [Cardiac involvement in thrombotic microangiopathies].
abstract: OBJECTIVE
  To describe cardiac involvement in patients with acute thrombotic microangiopathy (TMA).
  
  
  METHODS
  The case histories of 46 patients with proven TMA, including 17 patients diagnosed with atypical hemolytic uremic syndrome (aHUS) and 29 patients with catastrophic antiphospholipid syndrome (CAPS), were analyzed.
  
  
  RESULTS
  Different documentarily verified signs of cardiac involvement were revealed in 6 (13%) patients (5 and 1 patients diagnosed as having aHUS and CAPS, respectively). Five patients developed myocardial involvement at disease onset in the presence of multiple organ dysfunction.
  
  
  CONCLUSIONS
  Cases of cardiac involvement in TMA of various genesis are presented. The exact incidence of myocardial involvement and its prognostic value are unknown so far.
authors.affiliation: Department of Preventive and Emergency Cardiology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia.
authors.forename: D S
authors.initials: DS
authors.lastname: Tuter
authors.affiliation: Department of Preventive and Emergency Cardiology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia.
authors.forename: F Yu
authors.initials: FY
authors.lastname: Kopylov
authors.affiliation: Department of Nephrology and Hemodialysis, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: N L
authors.initials: NL
authors.lastname: Kozlovskaya
authors.affiliation: Department of Nephrology and Hemodialysis, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: K A
authors.initials: KA
authors.lastname: Demyanova
authors.affiliation: Department of Preventive and Emergency Cardiology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia.
authors.forename: D Yu
authors.initials: DY
authors.lastname: Shchekochikhin
authors.affiliation: Department of Nephrology and Hemodialysis, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: E M
authors.initials: EM
authors.lastname: Shilov
authors.affiliation: Department of Preventive and Emergency Cardiology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia.
authors.forename: A L
authors.initials: AL
authors.lastname: Syrkin
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000503:physiopathology; D065766:Atypical Hemolytic Uremic Syndrome / Q000150:complications / Q000503:physiopathology; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008297:Male; D006435:Renal Dialysis / Q000379:methods*; D051437:Renal Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D057049:Thrombotic Microangiopathies / Q000097:blood / Q000150:complications / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents