title: Mismatch of delayed perfusion volume between TTP and Tmax map of perfusion MRI.
abstract: OBJECTIVE
  To look for another set of parameters to predict the change in infarct size in acute stroke patients with a perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch.
  
  
  METHODS
  We reviewed 54 patients who had PWI-DWI mismatch and vascular occlusion on initial MRI and no recanalization of occluded vessel.
  
  
  RESULTS
  Time-to-peak and time-to-max (TTP-Tmax) perfusion mismatch volume was independently significant as a correlate of infarct volume change (P=.004).
  
  
  CONCLUSIONS
  The finding of a large TTP-Tmax perfusion delay mismatch volume in patients with acute stroke who have a PWI-DWI mismatch on an initial MRI may predict that the infarct volume will not increase despite persistent vascular occlusion.
authors.affiliation: Department of Radiology, Dong-A University Medical Center, 1,3-ga, Dongdaeshin-dong, Seo-gu, Busan 602-715, Korea.
authors.forename: Sanghyeon
authors.initials: S
authors.lastname: Kim
authors.affiliation: Department of Radiology, Dong-A University Medical Center, 1,3-ga, Dongdaeshin-dong, Seo-gu, Busan 602-715, Korea. Electronic address: myongjin.kang@gmail.com.
authors.forename: Myongjin
authors.initials: M
authors.lastname: Kang
authors.affiliation: Department of Radiology, Dong-A University Medical Center, 1,3-ga, Dongdaeshin-dong, Seo-gu, Busan 602-715, Korea.
authors.forename: Sunseob
authors.initials: S
authors.lastname: Choi
authors.affiliation: Department of Radiology, Dong-A University Medical Center, 1,3-ga, Dongdaeshin-dong, Seo-gu, Busan 602-715, Korea.
authors.forename: Dong Won
authors.initials: DW
authors.lastname: Kim
mesh_terms: D000368:Aged; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D020521:Stroke / Q000097:blood* / Q000473:pathology*; D010959:Tissue Plasminogen Activator / Q000097:blood*
chemical_list: D010959:Tissue Plasminogen Activator
keywords: Ischemic stroke; Perfusion; Time to maximum; Time to peak