title: The Repeatability Assessment of Three-Dimensional Capsule-Intraocular Lens Complex Measurements by Means of High-Speed Swept-Source Optical Coherence Tomography.
abstract: OBJECTIVE
  To rebuild the three-dimensional (3-D) model of the anterior segment by high-speed swept-source optical coherence tomography (SSOCT) and evaluate the repeatability of measurement for the parameters of capsule-intraocular lens (C-IOL) complex.
  
  
  METHODS
  Twenty-two pseudophakic eyes from 22 patients were enrolled. Three continuous SSOCT measurements were performed in all eyes and the tomograms obtained were used for 3-D reconstruction. The output data were used to evaluate the measurement repeatability. The parameters included postoperative aqueous depth (PAD), the area and diameter of the anterior capsule opening (Area and D), IOL tilt (IOL-T), horizontal, vertical, and space decentration of the IOL, anterior capsule opening, and IOL-anterior capsule opening.
  
  
  RESULTS
  PAD, IOL-T, Area, D, and all decentration measurements showed high repeatability. Repeated measure analysis showed there was no statistically significant difference among the three continuous measurements (all P > .05). Pearson correlation analysis showed high correlation between each pair of them (all r >0.90, P<0.001). ICCs were all more than 0.9 for all parameters. The 95% LoAs of all parameters were narrow for comparison of three measurements, which showed high repeatability for three measurements.
  
  
  CONCLUSIONS
  SSOCT is available to be a new method for the 3-D measurement of C-IOL complex after cataract surgery. This method presented high repeatability in measuring the parameters of the C-IOL complex.
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Xixia
authors.initials: X
authors.lastname: Ding
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Qinmei
authors.initials: Q
authors.lastname: Wang
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Pingjun
authors.initials: P
authors.lastname: Chang
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.affiliation: G.B. Bietti Foundation IRCCS, Rome, Italy.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Savini
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Jinhai
authors.initials: J
authors.lastname: Huang
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Shenghai
authors.initials: S
authors.lastname: Huang
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Yinying
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Na
authors.initials: N
authors.lastname: Liao
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Lin
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Yu
authors.affiliation: School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.|Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
authors.forename: Yun-e
authors.initials: YE
authors.lastname: Zhao
mesh_terms: D000368:Aged; D000465:Algorithms; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007910:Lenses, Intraocular; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications; D012029:Refraction, Ocular; D015203:Reproducibility of Results; D012984:Software; D041623:Tomography, Optical Coherence / Q000379:methods*