title: Simultaneous sonochemical-enzymatic coating of medical textiles with antibacterial ZnO nanoparticles.
abstract: The antimicrobial finishing is a must for production of medical textiles, aiming at reducing the bioburden in clinical wards and consequently decreasing the risk of hospital-acquired infections. This work reports for the first time on a simultaneous sonochemical/enzymatic process for durable antibacterial coating of cotton with zinc oxide nanoparticles (ZnO NPs). The novel technology goes beyond the "stepwise" concept we proposed recently for enzymatic pre-activation of the fabrics and subsequent sonochemical nano-coating, and is designed to produce "ready-to-use" antibacterial medical textiles in a single step. A multilayer coating of uniformly dispersed NPs was obtained in the process. The enzymatic treatment provides better adhesion of the ZnO NPs and, as a consequence, enhanced coating stability during exploitation. The NPs-coated cotton fabrics inhibited the growth of the medically relevant Staphylococcus aureus and Escherichia coli respectively by 67% and 100%. The antibacterial efficiency of these textile materials resisted the intensive laundry regimes used in hospitals, though only 33% of the initially deposited NPs remained firmly fixed onto the fabrics after multiple washings.
authors.affiliation: Group of Molecular and Industrial Biotechnology, Department of Chemical Engineering, Universitat Politècnica de Catalunya, Rambla Sant Nebridi 22, 08222 Terrassa, Spain.
authors.forename: Petya
authors.initials: P
authors.lastname: Petkova
authors.affiliation: Group of Molecular and Industrial Biotechnology, Department of Chemical Engineering, Universitat Politècnica de Catalunya, Rambla Sant Nebridi 22, 08222 Terrassa, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Francesko
authors.affiliation: Department of Chemistry, Kanbar Laboratory for Nanomaterials, Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan 52900, Israel.
authors.forename: Ilana
authors.initials: I
authors.lastname: Perelshtein
authors.affiliation: Department of Chemistry, Kanbar Laboratory for Nanomaterials, Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan 52900, Israel; The Department of Materials Science & Engineering, National Cheng Kung University, Tainan 70101, Taiwan.
authors.forename: Aharon
authors.initials: A
authors.lastname: Gedanken
authors.affiliation: Group of Molecular and Industrial Biotechnology, Department of Chemical Engineering, Universitat Politècnica de Catalunya, Rambla Sant Nebridi 22, 08222 Terrassa, Spain. Electronic address: tzanko.tzanov@upc.edu.
authors.forename: Tzanko
authors.initials: T
authors.lastname: Tzanov
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D055162:Biocatalysis; D002480:Cellulase / Q000378:metabolism*; D032561:Cotton Fiber; D004926:Escherichia coli / Q000187:drug effects; D007221:Industry; D053758:Nanoparticles / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D000069453:Ultrasonic Waves; D015034:Zinc Oxide / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D002480:Cellulase; D015034:Zinc Oxide
keywords: Antibacterial coatings; Cellulase; Medical textiles; Nanoparticles; Sonochemistry; Zinc oxide