title: Burden of hypertension in China over the past decades: Systematic analysis of prevalence, treatment and control of hypertension.
abstract: To review comprehensively the prevalence, treatment and control of hypertension; and to estimate the burden of hypertension in China, thereby aiding Chinese health policies for better prevention and control of this condition.
  
  
  
  PubMed, EMbase, China National Knowledge Infrastructure, Wanfang and Chongqing VIP databases were searched for population-based studies published in English and Chinese that described prevalence, treatment and control of hypertension in China, as well as deaths and disabilities attributed to hypertension. All research papers were published between January 1999 and May 2014. Data from 178 studies involving over 2,901,464 participants covering 30 provinces were pooled. Overall, rates of prevalence, treatment and control of hypertension were 28.9%, 35.3% and 13.4% in China. A statistically significant association was observed between temperature gradient and the prevalence of hypertension. There were 10,667 (95% confidence interval 8063-13,345) disability-adjusted life years per 100,000 people. In total, 78.3% of disability-adjusted life years were from years lived with disability and 21.7% from years of life lost due to premature mortality.
  
  
  
  Although there has been a slight improvement in rates for the treatment and control of hypertension, these rates were still suboptimal, especially for men and people living in rural areas. Low and middle-income provinces had a comparatively huge burden of hypertension, which is a considerable risk factor for reducing life expectancy. Our analysis may be helpful in generating a current overview of hypertension in China.
authors.affiliation: Department of Cardiology, Beijing Chao-Yang Hospital, Capital Medical University, China.
authors.forename: Yixuan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, China Center of Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, China.
authors.forename: Xiaoxia
authors.initials: X
authors.lastname: Peng
authors.affiliation: Center of Clinical Epidemiology and Evidence-based Medicine, Beijing Children's Hospital, Capital Medical University, China.
authors.forename: Xiaolu
authors.initials: X
authors.lastname: Nie
authors.affiliation: Center for Molecular Medicine and Experimental Therapeutics, University of Houston, USA.
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.affiliation: Center for Molecular Medicine and Experimental Therapeutics, University of Houston, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Weldon
authors.affiliation: Fu-Wai Hospital, Chinese Academy of Medical Sciences, China.
authors.forename: Weili
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Respiratory Medicine, China-Japan Friendship Hospital, Capital Medical University, Beijing, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Xiao
authors.affiliation: Department of Cardiology, Beijing Chao-Yang Hospital, Capital Medical University, China caijun7879@hotmail.com.
authors.forename: Jun
authors.initials: J
authors.lastname: Cai
mesh_terms: D002681:China / Q000453:epidemiology; D017281:Cost of Illness; D019468:Disease Management; D006801:Humans; D006973:Hypertension / Q000191:economics / Q000453:epidemiology / Q000628:therapy; D015995:Prevalence; D019057:Quality-Adjusted Life Years; D012307:Risk Factors
keywords: Hypertension; burden of hypertension; control rate; prevalence; treatment rate