title: Extensive Melanotic Neuroectodermal Tumor of Infancy.
abstract: The melanotic neuroectodermal tumor of infancy (MNTI) is a rare childhood neoplasm with an alarming but classical clinical presentation. We present the case of a 2-month-old male infant treated with surgery for an aggressive MNTI on the alveolar process of the maxilla. Radiographic examination showed a diffuse osteolytic radiolucent lesion in the right maxilla, and displacement and dysmorphic changes in the developing primary tooth buds. The patient remained well without evidence of recurrence for 6 months after surgery. We discussed clinicopathological features, management alternatives, and outcome.
authors.affiliation: Oral and Maxillofacial Surgery Department, Federal University of Ceará, Fortaleza, Brazil.
authors.forename: Assis Filipe Medeiros
authors.initials: AF
authors.lastname: Albuquerque
authors.affiliation: Department of Oral and Maxillofacial, Albert Sabin Hospital, Fortaleza, Ceará, Brazil.
authors.forename: José Ferreira
authors.initials: JF
authors.lastname: Cunha
authors.affiliation: Department of Oral and Maxillofacial, University Center of Christus (Unichristus), Fortaleza, Brazil. rafael.linard@hotmail.com.|University Center Christus, João Adolfo Gurgel Street, 133, Fortaleza, CEP 140120, Brazil. rafael.linard@hotmail.com.
authors.forename: Rafael Linard
authors.initials: RL
authors.lastname: Avelar
authors.affiliation: Department of Neurosurgery, Albert Sabin Hospital of Fortaleza, Fortaleza, Ceará, Brazil.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Juca
authors.affiliation: Department of Stomatology, Federal University of Ceará, Fortaleza, Brazil.
authors.forename: Fabio Wildson Gurgel
authors.initials: FW
authors.lastname: Costa
authors.affiliation: Department of Head and Neck Surgery, Albert Sabin Hospital of Fortaleza, Fortaleza, Ceará, Brazil.
authors.forename: Mario Sérgio
authors.initials: MS
authors.lastname: Macedo
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D008441:Maxillary Neoplasms / Q000473:pathology* / Q000601:surgery; D017600:Neuroectodermal Tumor, Melanotic / Q000473:pathology* / Q000601:surgery; D019647:Oral Surgical Procedures
chemical_list: D014408:Biomarkers, Tumor
keywords: Intra-oral mass; Jaw neoplasm; Melanotic neuroectodermal tumor of infancy (MNTI); Surgical excision; Tumor recurrence