title: Magnetic Nanoparticles: Material Engineering and Emerging Applications in Lithography and Biomedicine.
abstract: We present an interdisciplinary overview of material engineering and emerging applications of iron oxide nanoparticles. We discuss material engineering of nanoparticles in the broadest sense, emphasizing size and shape control, large-area self-assembly, composite/hybrid structures, and surface engineering. This is followed by a discussion of several non-traditional, emerging applications of iron oxide nanoparticles, including nanoparticle lithography, magnetic particle imaging, magnetic guided drug delivery, and positive contrast agents for magnetic resonance imaging. We conclude with a succinct discussion of the pharmacokinetics pathways of iron oxide nanoparticles in the human body -- an important and required practical consideration for anyin vivobiomedical application, followed by a brief outlook of the field.
authors.affiliation: Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, AL 35487.
authors.forename: Yuping
authors.initials: Y
authors.lastname: Bao
authors.affiliation: State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu 610054, China.
authors.forename: Tianlong
authors.initials: T
authors.lastname: Wen
authors.affiliation: Chemistry, Case Western Reserve University, Cleveland, OH, 44106.
authors.forename: Anna Cristina S
authors.initials: AC
authors.lastname: Samia
authors.affiliation: Lodespin Labs, PO Box 95632, Seattle WA 98145.
authors.forename: Amit
authors.initials: A
authors.lastname: Khandhar
authors.affiliation: Materials Science and Engineering, University of Washington, Seattle, 98195.
authors.forename: Kannan M
authors.initials: KM
authors.lastname: Krishnan
keywords: composite/hybrid structures; imaging and magnetic guided drug delivery; iron oxide nanoparticle pharmacokinetics; magnetic nanoparticles; self-assembly and lithography