title: Personality disorders among Spanish prisoners starting hepatitis C treatment: Prevalence and associated factors.
abstract: The purpose of this study was to assess the prevalence of personality disorders (PDs) and their associated factors in prisoners who initiate chronic hepatitis C (CHC) treatment in 25 Spanish prisons. The Personality Diagnostic Questionnaire-4 was used to diagnose PDs according to DSM-IV criteria. Factors potentially associated with a PD diagnosis were evaluated by logistic regression analysis. Two hundred and fifty-five patients were initially assessed and 62 (24.3%) were excluded due to an incomplete or invalid self-report screening questionnaire. PD prevalence was 70.5%, with antisocial PD being the most prevalent (46.1%). In terms of PD clusters, the most prevalent was cluster-B (55.4%). PD diagnosis was associated with HCV genotypes 1, 2, or 3 (odds ratio [OR] 2.14, 95% confidence interval [CI] 1.02-4.49). Patients with a cluster-B PD were more likely to be infected with HCV genotypes 1, 2, or 3 (OR 2.37, 95% CI 1.08-5.23) and be HIV-infected (OR 2.20, 95% CI 1.10-4.39), to report past-year injection drug use (OR 7.17, 95% CI 1.49-34.58), and to have stage 3 or 4 fibrosis (OR 2.16, 95% CI 1.06-4.49). The prevalence of PDs in Spanish prisoners who initiate CHC treatment is very high. PD management issues should be considered in treating CHC patients in prisons.
authors.affiliation: Health Services of Barcelona Men's Penitentiary Centre, Barcelona, Spain.
authors.forename: Andrés
authors.initials: A
authors.lastname: Marco
authors.affiliation: Health Services of Albolote Penitentiary Centre, Granada, Spain.
authors.forename: José J
authors.initials: JJ
authors.lastname: Antón
authors.affiliation: Health Services of Fontcalent Penitentiary Centre, Alicante, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Saiz de la Hoya
authors.affiliation: Health Services of Córdoba Penitentiary Centre, Córdoba, Spain.
authors.forename: José
authors.initials: J
authors.lastname: de Juan
authors.affiliation: Health Services of Sevilla Penitentiary Centre, Sevilla, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Faraco
authors.affiliation: Epidemiology Service, Public Health Agency of Barcelona, CIBER de Epidemiología y Salud Pública (CIBERESP), Spain.
authors.forename: Joan A
authors.initials: JA
authors.lastname: Caylà
authors.affiliation: Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau), CIBER de Salud Mental (CIBERSAM), Barcelona, Spain. Electronic address: jtrujols@santpau.cat.
authors.forename: Joan
authors.initials: J
authors.lastname: Trujols
mesh_terms: D000328:Adult; D000987:Antisocial Personality Disorder / Q000453:epidemiology / Q000523:psychology; D000998:Antiviral Agents / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000523:psychology; D006526:Hepatitis C / Q000188:drug therapy / Q000523:psychology* / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010554:Personality Disorders / Q000453:epidemiology* / Q000523:psychology; D015995:Prevalence; D011329:Prisoners / Q000523:psychology* / Q000706:statistics & numerical data; D011330:Prisons / Q000706:statistics & numerical data; D012044:Regression Analysis; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D000998:Antiviral Agents
keywords: Chronic hepatitis C; Epidemiology; Personality Disorder Questionnaire-4 (PDQ-4); Personality disorder; Prevalence; Prisons