title: Pediatric Melanoma and Atypical Melanocytic Neoplasms.
abstract: Melanoma is uncommon in the pediatric age range, but is increasing in frequency and often presents with atypical features compared to the classic ABCDE criteria common to adult melanoma cases. Moreover, many melanocytic neoplasms in childhood pose diagnostic challenges to the pathologist, and sometimes cannot be unequivocally classified as benign nevi or melanoma. This chapter addresses the evaluation and management of pediatric patients with melanoma and atypical melanocytic neoplasms, including the roles of and unresolved questions surrounding sentinel lymph node biopsy, completion lymphadenectomy, adjuvant therapy, and treatment of advanced disease.
authors.affiliation: Department of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA.
authors.forename: Radhika
authors.initials: R
authors.lastname: Sreeraman Kumar
authors.affiliation: Department of Anatomic Pathology, Moffitt Cancer Center, Tampa, FL, USA.|Department of Cutaneous Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA.|Department of Pathology and Cell Biology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.|Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA.|Department of Dermatology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
authors.forename: Jane L
authors.initials: JL
authors.lastname: Messina
authors.affiliation: Department of Cutaneous Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA.|Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA.|Adolescent and Young Adult (AYA) Program, Sarcoma Department, Moffitt Cancer Center, Tampa, FL, USA.|Department of Hematology/Oncology , All Children's Hospital Johns Hopkins Medicine , St. Petersburg, FL, USA.
authors.forename: Damon
authors.initials: D
authors.lastname: Reed
authors.affiliation: Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
authors.forename: Fariba
authors.initials: F
authors.lastname: Navid
authors.affiliation: Department of Cutaneous Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA. vernon.sondak@moffitt.org.|Department of Oncologic Sciences and Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA. vernon.sondak@moffitt.org.
authors.forename: Vernon K
authors.initials: VK
authors.lastname: Sondak
mesh_terms: D002648:Child; D006801:Humans; D008197:Lymph Node Excision; D008545:Melanoma / Q000145:classification / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D018332:Nevus, Epithelioid and Spindle Cell / Q000145:classification / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D012307:Risk Factors; D021701:Sentinel Lymph Node Biopsy; D012878:Skin Neoplasms / Q000145:classification / Q000209:etiology / Q000473:pathology / Q000628:therapy*
keywords: Adolescent and young adult (AYA) oncology; Atypical melanocytic neoplasms; Melanoma; Pediatrics; Sentinel node biopsy