title: Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans, South Korea.
abstract: We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody responses developed by the third week of illness. Delayed antibody responses with the neutralization test were associated with more severe disease.
authors.forename: Wan Beom
authors.initials: WB
authors.lastname: Park
authors.forename: Ranawaka A P M
authors.initials: RA
authors.lastname: Perera
authors.forename: Pyoeng Gyun
authors.initials: PG
authors.lastname: Choe
authors.forename: Eric H Y
authors.initials: EH
authors.lastname: Lau
authors.forename: Seong Jin
authors.initials: SJ
authors.lastname: Choi
authors.forename: June Young
authors.initials: JY
authors.lastname: Chun
authors.forename: Hong Sang
authors.initials: HS
authors.lastname: Oh
authors.forename: Kyoung-Ho
authors.initials: KH
authors.lastname: Song
authors.forename: Ji Hwan
authors.initials: JH
authors.lastname: Bang
authors.forename: Eu Suk
authors.initials: ES
authors.lastname: Kim
authors.forename: Hong Bin
authors.initials: HB
authors.lastname: Kim
authors.forename: Sang Won
authors.initials: SW
authors.lastname: Park
authors.forename: Nam Joong
authors.initials: NJ
authors.lastname: Kim
authors.forename: Leo Lit
authors.initials: LL
authors.lastname: Man Poon
authors.forename: Malik
authors.initials: M
authors.lastname: Peiris
authors.forename: Myoung-Don
authors.initials: MD
authors.lastname: Oh
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D000915:Antibody Affinity; D000917:Antibody Formation / Q000276:immunology; D002162:Camelus / Q000276:immunology; D018352:Coronavirus Infections / Q000453:epidemiology / Q000276:immunology* / Q000473:pathology; D005260:Female; D006801:Humans / Q000097:blood / Q000821:virology; D007700:Kinetics; D008297:Male; D065207:Middle East Respiratory Syndrome Coronavirus / Q000276:immunology* / Q000472:pathogenicity*; D056910:Republic of Korea / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral
keywords: MERS; MERS-CoV; Middle East respiratory syndrome; Middle East respiratory syndrome coronavirus; South Korea; antibody; clinical correlates; coronavirus; diagnostics; humans; immunity; kinetics; seroepidemiologic data; serologic responses; severity; viruses