title: [CORRELATIONAL RELATIONSHIP BETWEEN DURATION OF A "COLD" ISCHEMIA PERIOD, THROMBOCYTOPENIA AND SEVERITY OF A HEPATIC REPERFUSIVE DAMAGE IN PATIENTS AFTER ITS TRANSPLANTATION].
abstract: Reperfusive hepatic damage, one of the severe complications after hepatic transplantation, occurs immediately after inclusion of the donor organ into the blood circulation of a recipient. It is considered one of principal causes of early rejection of the transplant. Connection between thrombocytopenia in a patient and duration of period of a donor's "cold" hepatic ischemia was studied. The changes in microcirculation due to the thrombocytes accumulation (sequestration) in a sinusoid vessels constitutes a main target in the ischemic-reperfusive damage of the liver. During the first days after hepatic transplantation the thrombocytes quantity have reduced, the correlation dependence between this process and duration of a "cold" ischemia and functional activity of a liver transplanted was established.
authors.forename: Iskandarov Emil
authors.initials: IE
authors.lastname: Alimamed Ogli
authors.forename: A G
authors.initials: AG
authors.lastname: Khandoga
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001792:Blood Platelets / Q000473:pathology*; D003080:Cold Temperature; D006801:Humans; D008099:Liver / Q000098:blood supply / Q000473:pathology; D016031:Liver Transplantation; D008833:Microcirculation; D019188:Organ Preservation Solutions / Q000737:chemistry; D015427:Reperfusion Injury / Q000150:complications / Q000473:pathology*; D012720:Severity of Illness Index; D013921:Thrombocytopenia / Q000150:complications / Q000473:pathology*; D013997:Time Factors
chemical_list: D015415:Biomarkers; D019188:Organ Preservation Solutions; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase