title: In vivo effects of Maillard reaction products derived from biscuits.
abstract: The antioxidant activity, antihypertensive effect and prebiotic activity of Maillard reaction products (MRPs) derived from biscuits were investigated in Wistar rats. Animals were fed the following diets for 6 weeks: control (AIN-93 diet); Asc-diet (AIN-93 diet with ascorbic acid in the drinking water); HT-B diet (containing high amount of MRP derived from biscuits) and LT-B diet (containing negligible amounts of biscuit MRP). Serum antioxidant activity (FRAP, ABTS), as well as lipid peroxidation (TBARS) were determined at the end of the experiment. Results showed that dietary MRP reduced the food efficiency, increased the antioxidant activity of serum, increased the ratio between lactic and total aerobic bacteria, increased water-holding capacity of faeces and reduced blood pressure, but did not reduce mineral absorption. Therefore, the biscuit MRP functional claims could be demonstrated by an in vivo study.
authors.affiliation: Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CIDCA), Facultad de Ciencias Exactas, UNLP - CCT La Plata - CONICET, 47 y 116, 1900 La Plata, Argentina.
authors.forename: Mariela
authors.initials: M
authors.lastname: Patrignani
authors.affiliation: Centro de Investigaciones Cardiovasculares, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Facultad de Ciencias Médicas, UNLP, 60 y 120, 1900, La Plata, Argentina.
authors.forename: Gustavo Juan
authors.initials: GJ
authors.lastname: Rinaldi
authors.affiliation: Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CIDCA), Facultad de Ciencias Exactas, UNLP - CCT La Plata - CONICET, 47 y 116, 1900 La Plata, Argentina. Electronic address: cel@quimica.unlp.edu.ar.
authors.forename: Cecilia Elena
authors.initials: CE
authors.lastname: Lupano
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000032:analysis*; D001205:Ascorbic Acid; D004032:Diet; D005243:Feces / Q000737:chemistry; D005502:Food; D000069196:Gastrointestinal Microbiome; D015227:Lipid Peroxidation; D015416:Maillard Reaction; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis; D014867:Water
chemical_list: D000975:Antioxidants; D017392:Thiobarbituric Acid Reactive Substances; D014867:Water; D001205:Ascorbic Acid
keywords: Antihypertensive activity; Antioxidant activity; Biscuits; In vivo; Maillard reaction products; Prebiotic effect