title: AdVanceXP male sling: 2-year results of a multicentre study.
abstract: OBJECTIVE
  For the treatment of persistent post-prostatectomy incontinence (PPI), several surgical treatment options including male slings are available. In 2010, the second generation of the retrourethral male sling Advance, AdVanceXP, was introduced. Aim of the study was to examine in a prospective multicentre study the outcome of AdVanceXP in the treatment of PPI.
  
  
  METHODS
  Ninety-four patients were treated with AdVanceXP. Patients with nocturnal incontinence, previous incontinence surgery, with coaptive zone <1 cm and irradiated patients were excluded. Measurements included: daily pad usage, 24-h pad weight test, post-operative pain in the visual analogue scale, International Quality of Life questionnaire, International Consultation on Incontinence Questionnaire short form, IEEF5 and Patient Global Impression of Improvement. Adverse events were recorded. All patients with no pads and 0-5 g in the 24-h pad test were defined as cured and those with a reduction in urine loss >50 % as improved.
  
  
  RESULTS
  Preoperatively, the median 24-h pad weight test was 274 g and daily pad usage was 3. At 1-year follow-up, 66.3 % of patients could be classified as cured and 25.3 % as improved. After 2 years, 73.1 % could be classified as cured and 19.6 % as improved. Urine loss decreased (p < 0.001), and quality of life improved significantly (p < 0.001). Mean PGI was 1.5 after 1 year and 1.4 after 2 years. Majority of complications were minor. No intraoperative complications and five serious post-operative events occurred (grade IIIB complications). No explantation was necessary.
  
  
  CONCLUSIONS
  AdVanceXP, when correctly indicated, shows good effectiveness and low complication rates after up to 2 years.
authors.affiliation: Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, Campus Grosshadern, 81377, Munich, Germany. Ricarda.Bauer@med.uni-muenchen.de.
authors.forename: Ricarda M
authors.initials: RM
authors.lastname: Bauer
authors.affiliation: Department of Urology, Marienklinik, Bolzano, Italy.
authors.forename: Christian
authors.initials: C
authors.lastname: Gozzi
authors.affiliation: Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, Campus Grosshadern, 81377, Munich, Germany.
authors.forename: Benedikt
authors.initials: B
authors.lastname: Klehr
authors.affiliation: Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, Campus Grosshadern, 81377, Munich, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Kretschmer
authors.affiliation: Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, Campus Grosshadern, 81377, Munich, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Grabbert
authors.affiliation: Department of Urology, Medical University, Innsbruck, Austria.
authors.forename: Peter
authors.initials: P
authors.lastname: Rehder
authors.affiliation: Helios Amper Klinik Dachau, Department of Urology, Ludwig-Maximilians-University Teaching Hospital, Dachau, Germany.
authors.forename: Florian
authors.initials: F
authors.lastname: May
authors.affiliation: Department of Urology, Ludwig-Maximilians-University, Marchioninistr. 15, Campus Grosshadern, 81377, Munich, Germany.
authors.forename: Christian G
authors.initials: CG
authors.lastname: Stief
authors.affiliation: Department of Urology, LKH Voecklabruck, Voecklabruck, Austria.
authors.forename: Peter
authors.initials: P
authors.lastname: Gebhartl
authors.affiliation: Urology, St. Josef-Krankenhaus, Hamm, Germany.
authors.forename: Roland
authors.initials: R
authors.lastname: Homberg
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000601:surgery*; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects; D011474:Prosthesis Design; D053825:Suburethral Slings; D013997:Time Factors; D014550:Urinary Incontinence, Stress / Q000209:etiology / Q000601:surgery*
keywords: AdVanceXP; Complications; Male sling; Post-prostatectomy incontinence; Quality of life; Retrourethral sling