title: [Effect of occupational stress on neurotransmitters in petroleum workers].
abstract: OBJECTIVE
  To explore the effects of occupational stress on neurotransmitters in petroleum workers.
  
  
  METHODS
  178 petroleum workers with the length of service ≥ 1 year were recruited to the subjects by the questionnaire of OSI-R. The levels of 5-hydroxy tryptamine (5-HT), norepinephrine (NE), neuropeptide Y (NPY) and substance P (SP) in serum were measured. The subjects were classified into 3 groups according to the scores of occupational stress.
  
  
  RESULTS
  The levels of 5-HT NE and SP for over 15 working years were higher than those of less than 15 years (P < 0. 05). There were differences (P < 0. 05) on 5-HT, NE, NPY and SP in different occupational stress degree groups, multiple comparison showed high. occupational stress group was higher than those of low occupational stress group. Multivariate correlation analysis showed that the occupational stress and sleep quality component scores correlated positively with the 5-HT, NE and SP (P < 0. 05) and correlated inversely with NPY in petroleum workers (P < 0. 05).
  
  
  CONCLUSIONS
  Occupational stress in petroleum workers is correlated with serum monoamine and neuropeptides neurotransmitters, and it may affect serum levels of monoamine and neuropeptides neurotransmitters.
authors.forename: Yu
authors.initials: Y
authors.lastname: Jiang
authors.forename: Yulong
authors.initials: Y
authors.lastname: Lian
authors.forename: Ning
authors.initials: N
authors.lastname: Tao
authors.forename: Hua
authors.initials: H
authors.lastname: Ge
authors.forename: Jiwen
authors.initials: J
authors.lastname: Liu
mesh_terms: D006801:Humans; D009478:Neuropeptide Y / Q000097:blood; D018377:Neurotransmitter Agents / Q000097:blood*; D009638:Norepinephrine / Q000097:blood; D009784:Occupational Diseases / Q000523:psychology*; D010578:Petroleum; D012701:Serotonin / Q000097:blood; D013315:Stress, Psychological / Q000523:psychology*; D011795:Surveys and Questionnaires
chemical_list: D009478:Neuropeptide Y; D018377:Neurotransmitter Agents; D010578:Petroleum; D012701:Serotonin; D009638:Norepinephrine