title: Automated Quantitative Nuclear Cardiology Methods.
abstract: Quantitative analysis of SPECT and PET has become a major part of nuclear cardiology practice. Current software tools can automatically segment the left ventricle, quantify function, establish myocardial perfusion maps, and estimate global and local measures of stress/rest perfusion, all with minimal user input. State-of-the-art automated techniques have been shown to offer high diagnostic accuracy for detecting coronary artery disease, as well as predict prognostic outcomes. This article briefly reviews these techniques, highlights several challenges, and discusses the latest developments.
authors.affiliation: Departments of Imaging and Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
authors.forename: Manish
authors.initials: M
authors.lastname: Motwani
authors.affiliation: Departments of Imaging and Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Berman
authors.affiliation: Departments of Imaging and Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
authors.forename: Guido
authors.initials: G
authors.lastname: Germano
authors.affiliation: Departments of Imaging and Medicine, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA; David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. Electronic address: piotr.slomka@cshs.org.
authors.forename: Piotr
authors.initials: P
authors.lastname: Slomka
mesh_terms: D006801:Humans; D055414:Myocardial Perfusion Imaging; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D015899:Tomography, Emission-Computed, Single-Photon
keywords: Automated quantitation; Ischemia; Left ventricular ejection fraction; Myocardial function; Myocardial perfusion; PET; SPECT; Total perfusion deficit