title: [Unraveling R₀: considerations for public health applications].
abstract: We assessed public health use of R0, the basic reproduction number, which estimates the speed at which a disease is capable of spreading in a population. These estimates are of great public health interest, as evidenced during the 2009 influenza A (H1N1) vírus pandemic. We reviewed methods commonly used to estimate R0, examined their practical utility, and assessed how estimates of this epidemiological parameter can inform mitigation strategy decisions. In isolation, R0 is a suboptimal gauge of infectious disease dynamics across populations; other disease parameters may provide more useful information. Nonetheless, estimation of R0 for a particular population is useful for understanding transmission in the study population. Considered in the context of other epidemiologically important parameters, the value of R0 may lie in better understanding an outbreak and in preparing a public health response.
authors.affiliation: Instituto Eck para la Salud Global.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Ridenhour
authors.affiliation: Instituto Eck para la Salud Global.
authors.forename: Jessica M
authors.initials: JM
authors.lastname: Kowalik
authors.affiliation: División de Gripe, Centros para el Control y la Prevención de Enfermedades, Atlanta, Georgia, Estados Unidos de América.
authors.forename: David K
authors.initials: DK
authors.lastname: Shay
mesh_terms: D050936:Basic Reproduction Number; D003141:Communicable Diseases / Q000453:epidemiology / Q000635:transmission*; D004196:Disease Outbreaks; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000453:epidemiology / Q000635:transmission; D008962:Models, Theoretical; D009656:North America / Q000453:epidemiology; D058873:Pandemics; D011634:Public Health / Q000379:methods*