title: [THE USE OF "REAMBERIN" AS BIOLOGICAL RESPONSE MODIFIER TO INCREASE THE NATURAL KILLER CELLS' CYTOTOXICITY IN PATIENTS WITH LUNG TUBERCULOSIS].
abstract: The effect of the drug "Reamberin" cytotoxic activity of natural killer cells (EC) in an experimental model in the blood samples of patients with pulmonary tuberculosis and healthy donors. Simulation acute systemic inflammation by adding to the culture medium of BCG. After 48 hours, selection was performed mononuclear peripheral blood by gradient centrifugation tests set cytotoxic tumor cell line K-562. Revealed the stimulating effect of the drug "Reamberin" cytotoxic activity of natural killer cells. Metabolic Correction has had a positive impact on the energy metabolism of blood natural killer cells, to increase their survial and cytotoxicity.
authors.forename: A I
authors.initials: AI
authors.lastname: Kholamov
authors.forename: V G
authors.initials: VG
authors.lastname: Mirzomogomedova
authors.forename: D A
authors.initials: DA
authors.lastname: Chernoshey
authors.forename: E S
authors.initials: ES
authors.lastname: Lizunov
mesh_terms: D000328:Adult; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D020014:K562 Cells; D007694:Killer Cells, Natural / Q000276:immunology* / Q000473:pathology; D008297:Male; D008536:Meglumine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D009163:Mycobacterium bovis / Q000276:immunology; D013386:Succinates / Q000008:administration & dosage*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000276:immunology* / Q000473:pathology
chemical_list: C549374:Reamberin; D013386:Succinates; D008536:Meglumine