title: Gabapentin Use in the Neonatal Intensive Care Unit.
abstract: Gabapentin was used for the treatment of term and preterm infants with suspected visceral hyperalgesia caused by a variety of neurologic and gastrointestinal morbidities. Improved feeding tolerance and decreased irritability were seen, as well as decreased usage of opioids and benzodiazepines. Adverse events occurred with abrupt discontinuation of this medication.
authors.affiliation: Division of Neonatology, Department of Pediatrics, Duke University Medical Center, Durham, NC.
authors.forename: Laura
authors.initials: L
authors.lastname: Edwards
authors.affiliation: Division of Neonatology, Department of Pediatrics, Duke University Medical Center, Durham, NC.
authors.forename: Stephen
authors.initials: S
authors.lastname: DeMeo
authors.affiliation: Department of Pharmacy, Duke University Medical Center, Durham, NC.
authors.forename: Chi D
authors.initials: CD
authors.lastname: Hornik
authors.affiliation: Division of Neonatology, Department of Pediatrics, Duke University Medical Center, Durham, NC.
authors.forename: C Michael
authors.initials: CM
authors.lastname: Cotten
authors.affiliation: Division of Neonatology, Department of Pediatrics, Duke University Medical Center, Durham, NC.
authors.forename: P Brian
authors.initials: PB
authors.lastname: Smith
authors.affiliation: Division of Pediatric Neurology, Department of Pediatrics, Duke University Medical Center, Durham, NC.
authors.forename: Carolyn
authors.initials: C
authors.lastname: Pizoli
authors.affiliation: Department of Pediatrics, Children's Hospital Boston, Boston, MA.
authors.forename: Julie M
authors.initials: JM
authors.lastname: Hauer
authors.affiliation: Division of Neonatology, Department of Pediatrics, Duke University Medical Center, Durham, NC. Electronic address: margarita.bidegain@dm.duke.edu.
authors.forename: Margarita
authors.initials: M
authors.lastname: Bidegain
mesh_terms: D000588:Amines / Q000008:administration & dosage* / Q000009:adverse effects; D000700:Analgesics / Q000008:administration & dosage* / Q000009:adverse effects; D001569:Benzodiazepines / Q000008:administration & dosage* / Q000009:adverse effects; D003509:Cyclohexanecarboxylic Acids / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D000077206:Gabapentin; D006801:Humans; D006930:Hyperalgesia / Q000188:drug therapy*; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data*; D008297:Male; D012189:Retrospective Studies; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D000588:Amines; D000700:Analgesics; D003509:Cyclohexanecarboxylic Acids; D001569:Benzodiazepines; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin