title: Noninferiority is almost certain with lenient noninferiority margins.
authors.affiliation: Department of Medicine and Aging Sciences, University of Chieti, Via dei Vestini 5, 66013 Chieti, Italy; Regional Health Care Agency of Abruzzo, Via Attilio Monti 9, Pescara, Italy.
authors.forename: Maria Elena
authors.initials: ME
authors.lastname: Flacco
authors.affiliation: Department of Medicine and Aging Sciences, University of Chieti, Via dei Vestini 5, 66013 Chieti, Italy; Regional Health Care Agency of Abruzzo, Via Attilio Monti 9, Pescara, Italy.
authors.forename: Lamberto
authors.initials: L
authors.lastname: Manzoli
authors.affiliation: Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA, USA; Department of Statistics, Stanford University School of Humanities and Sciences, Stanford, CA, USA; Meta-Research Innovation Center at Stanford (METRICS), Stanford, CA, USA. Electronic address: jioannid@stanford.edu.
authors.forename: John P A
authors.initials: JP
authors.lastname: Ioannidis
mesh_terms: D004345:Drug Industry / Q000191:economics*; D016032:Randomized Controlled Trials as Topic / Q000191:economics*; D012109:Research Support as Topic / Q000706:statistics & numerical data*