title: SNPTracker: A Swift Tool for Comprehensive Tracking and Unifying dbSNP rs IDs and Genomic Coordinates of Massive Sequence Variants.
abstract: The reference single nucleotide polymorphism (rs) ID in dbSNP (http://www.ncbi.nlm.nih.gov/SNP/) is a key resource identifier, which is widely used in human genetics and genomics studies. However, its application is often complicated by the varied IDs of different versions. Here, we developed a user-friendly tool, SNPTracker, for comprehensively tracking and unifying the rs IDs and genomic coordinates of massive sequence variants at a time. It worked perfectly, and had much higher accuracy and capacity than two alternative utilities in our proof-of-principle examples. SNPTracker will greatly facilitate genetic data exchange and integration in the postgenome-wide association study era.
authors.affiliation: Department of Psychiatry, University of Hong Kong.
authors.forename: Jia-En
authors.initials: JE
authors.lastname: Deng
authors.affiliation: Department of Psychiatry, University of Hong Kong Centre for Genomic Sciences, University of Hong Kong State Key Laboratory for Cognitive and Brain Sciences, University of Hong Kong Center for Reproduction, Development and Growth, University of Hong Kong, Hong Kong SAR, China.
authors.forename: Pak C
authors.initials: PC
authors.lastname: Sham
authors.affiliation: Department of Psychiatry, University of Hong Kong Centre for Genomic Sciences, University of Hong Kong State Key Laboratory for Cognitive and Brain Sciences, University of Hong Kong Center for Reproduction, Development and Growth, University of Hong Kong, Hong Kong SAR, China. mxli@hku.hk.
authors.forename: Miao-Xin
authors.identifier: http://orcid.org/0000-0002-4733-0109
authors.initials: MX
authors.lastname: Li
mesh_terms: D030561:Databases, Nucleic Acid; D023281:Genomics / Q000379:methods*; D020641:Polymorphism, Single Nucleotide; D012984:Software
keywords: RefSnp (rs) ID; dbSNP; genomic coordinate; sequence variant; single nucleotide polymorphism (SNP)