title: [THE TRUE OR FALSE BACTERIEMIA: THE SIGNIFICANCE OF EVALUATION CRITERIA OF CLINICAL SIGNIFICANCE OF POSITIVE HEMOCULTURE].
abstract: The diagnostic of infections of blood flow using technique of hemofermentation (blood inoculation) is one of the most significant functions of laboratory of clinical microbiology. The effectiveness of the given technique depends on many factors, including criteria of evaluation of clinical significance of episode of bacteriemia and isolated microorganism applied by physician-microbiologist. The intelligent analysis of received results is needed. The physician-microbiologist has to determine if microorganism isolated from given blood sample, is a genuine agent of infections of bloodflow or it is only effect of contamination of analyzed sample at certain stage. The article presents data concerning taxonomic structure of microorganisms isolated under episodes of bacteriemia of adult oncologic hematologic patients during 2005-2013. The criteria of evaluation of clinical significance of episode of bacteriemia and isolated microorganism are described. The given criteria are developed in the N.N. Blokhin Russian oncological research center and are applied since 1977. The cases of contamination and genuine bacteriemia are established. The comparative analysis of international data and results of one's own study are carried out.
authors.forename: N S
authors.initials: NS
authors.lastname: Bagirova
mesh_terms: D000328:Adult; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D001426:Bacterial Proteins / Q000302:isolation & purification*; D015373:Bacterial Typing Techniques; D002175:Candida / Q000737:chemistry / Q000254:growth & development / Q000302:isolation & purification; D002177:Candidiasis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D003470:Culture Media; D005189:False Positive Reactions; D005260:Female; D005656:Fungal Proteins / Q000302:isolation & purification*; D006090:Gram-Negative Bacteria / Q000737:chemistry / Q000254:growth & development / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D006094:Gram-Positive Bacteria / Q000737:chemistry / Q000254:growth & development / Q000302:isolation & purification; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D019337:Hematologic Neoplasms / Q000150:complications / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media; D005656:Fungal Proteins