title: Interventions for the management of external root resorption.
abstract: BACKGROUND
  External root resorption is a pathological process, which tends to occur following a wide range of mechanical or chemical stimuli such as infection, pressure, trauma or orthodontic tooth movement. Although it is predominantly detected by radiography, in some cases root resorption may be identified by clinical symptoms such as pain, swelling and mobility of the tooth. Treatment alternatives are case-dependent and aim to address the cause of the resorption and aid the regeneration of the resorptive lesion.
  
  
  OBJECTIVE
  To evaluate the effectiveness of any interventions that can be used in the management of external root resorption in permanent teeth.
  
  
  METHODS
  The following electronic databases were searched: the Cochrane Oral Health Group Trials Register (to 14 October 2015), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, 2015, Issue 9), MEDLINE via OVID (1946 to 14 October 2015) and EMBASE via OVID (1980 to 14 October 2015). We searched the US National Institutes of Health Trials Register (http://clinicaltrials.gov) and the WHO Clinical Trials Registry Platform for ongoing trials. No restrictions were placed on the language or date of publication when searching the electronic databases.
  
  
  METHODS
  We included randomised controlled trials of permanent teeth with any type of external root resorption, which has been confirmed by clinical and radiological examination, comparing one type of intervention (root canal medications and canal filling, splinting or extraction of teeth or the surgical removal of any relevant pathology) with another, or with placebo or no treatment.
  
  
  METHODS
  Two review authors screened search records independently. Full papers were obtained for potentially relevant trials. If data had been extracted, the statistical guidelines set out in the Cochrane Handbook would have been followed.
  
  
  RESULTS
  No randomised controlled trials that met the inclusion criteria were identified. However, we identified one ongoing study that is potentially relevant to this review and will be assessed when it is published.
  
  
  CONCLUSIONS
  We were unable to identify any reports of randomised controlled trials regarding the efficacy of different interventions for the management of external root resorption. In view of the lack of reliable evidence on this topic, clinicians must decide on the most appropriate means of managing this condition according to their clinical experience with regard to patient-related factors. There is a need for well designed and conducted clinical trials on this topic, which conform to the CONSORT statement (www.consort-statement.org/).
authors.affiliation: Department of Endodontics and Iranian Dental Research Centre, Shahid Beheshti School of Dentistry, Daneshjou Boulevard, Evin, Tehran, Iran, 19834.
authors.forename: Zohreh
authors.initials: Z
authors.lastname: Ahangari
authors.forename: Mona
authors.initials: M
authors.lastname: Nasser
authors.forename: Mina
authors.initials: M
authors.lastname: Mahdian
authors.forename: Zbys
authors.initials: Z
authors.lastname: Fedorowicz
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Marchesan
mesh_terms: D019229:Dentition, Permanent; D006801:Humans; D012391:Root Resorption / Q000628:therapy*