title: Update on diagnosis and treatment of idiopathic pulmonary fibrosis.
abstract: Idiopathic pulmonary fibrosis is a type of chronic fibrosing interstitial pneumonia, of unknown etiology, which is associated with a progressive decrease in pulmonary function and with high mortality rates. Interest in and knowledge of this disorder have grown substantially in recent years. In this review article, we broadly discuss distinct aspects related to the diagnosis and treatment of idiopathic pulmonary fibrosis. We list the current diagnostic criteria and describe the therapeutic approaches currently available, symptomatic treatments, the action of new drugs that are effective in slowing the decline in pulmonary function, and indications for lung transplantation.
authors.affiliation: Departamento de Clínica Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brasil.
authors.forename: José
authors.initials: J
authors.lastname: Baddini-Martinez
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil.
authors.forename: Bruno Guedes
authors.initials: BG
authors.lastname: Baldi
authors.affiliation: Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil.
authors.forename: Cláudia Henrique da
authors.initials: CH
authors.lastname: Costa
authors.affiliation: Hospital Ana Nery, Salvador, Brasil.
authors.forename: Sérgio
authors.initials: S
authors.lastname: Jezler
authors.affiliation: Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brasil.
authors.forename: Mariana Silva
authors.initials: MS
authors.lastname: Lima
authors.affiliation: Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil.
authors.forename: Rogério
authors.initials: R
authors.lastname: Rufino
mesh_terms: D015897:Comorbidity; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D012307:Risk Factors; D000067251:Symptom Flare Up; D016896:Treatment Outcome