title: [Pathological and clinical correlations in renal AA amyloidosis: A Moroccan series of 30 cases].
abstract: OBJECTIVE
  Study of histological and clinical correlations of 30 cases of renal amyloidosis AA diagnosed between November 2010 and December 2012.
  
  
  RESULTS
  The main causes associated with amyloidosis AA were represented by chronic infectious diseases (60%). Nephrotic syndrome and renal failure were observed in 94% and 73% respectively. The distribution of amyloid deposits: 90% of patients had a glomerular form and 10% had a vascular form. Inflammatory reaction associated with AA renal amyloidosis was present in 50% of cases. This inflammation was observed near amyloid deposits associated with a deposition of immunoglobulin chains and/or complement factors.
  
  
  CONCLUSIONS
  Our study confirms the predominance of AA amyloidosis complicating chronic infectious diseases, especially tuberculosis. Our data point out a relationship between the morphology of renal AA amyloidosis, its clinical presentation and prognosis.
authors.affiliation: Laboratoire d'anatomie cytologie pathologiques, faculté de médecine et de pharmacie, université Mohamed V, hôpital d'enfants, Rabat, Maroc. Electronic address: asmae.bziz@gmail.com.
authors.forename: Asmae
authors.initials: A
authors.lastname: Bziz
authors.affiliation: Laboratoire d'anatomie cytologie pathologiques, faculté de médecine et de pharmacie, université Mohamed V, hôpital d'enfants, Rabat, Maroc.
authors.forename: Lamia
authors.initials: L
authors.lastname: Rouas
authors.affiliation: Laboratoire d'anatomie cytologie pathologiques, faculté de médecine et de pharmacie, université Mohamed V, hôpital d'enfants, Rabat, Maroc.
authors.forename: Najat
authors.initials: N
authors.lastname: Lamalmi
authors.affiliation: Laboratoire d'anatomie cytologie pathologiques, faculté de médecine et de pharmacie, université Mohamed V, hôpital d'enfants, Rabat, Maroc.
authors.forename: Abderrahmane
authors.initials: A
authors.lastname: Malihy
authors.affiliation: Laboratoire d'anatomie cytologie pathologiques, faculté de médecine et de pharmacie, université Mohamed V, hôpital d'enfants, Rabat, Maroc.
authors.forename: Nadia
authors.initials: N
authors.lastname: Cherradi
authors.affiliation: Service de néphrologie, faculté de médecine et de pharmacie, université Mohamed V, hôpital Ibn Sina (Avicenne), Rabat, Maroc.
authors.forename: Naima
authors.initials: N
authors.lastname: Ouzeddoun
authors.affiliation: Service de néphrologie, faculté de médecine et de pharmacie, université Mohamed V, hôpital Ibn Sina (Avicenne), Rabat, Maroc.
authors.forename: Rabia
authors.initials: R
authors.lastname: Bayahia
authors.affiliation: Service de néphrologie, faculté de médecine et de pharmacie, université Mohamed V, hôpital Ibn Sina (Avicenne), Rabat, Maroc.
authors.forename: Kaoutar
authors.initials: K
authors.lastname: Flayou
authors.affiliation: Laboratoire de biostatistique, recherche clinique et épidémiologie (LBRCE), faculté de médecine et de pharmacie, université Mohamed V, Rabat, Maroc.
authors.forename: Sanae
authors.initials: S
authors.lastname: Chala
authors.affiliation: Plateau technique de recherche, faculté de médecine et de pharmacie, université Mohamed V, Rabat, Maroc.
authors.forename: Aziz
authors.initials: A
authors.lastname: Bouclouze
authors.affiliation: Centre de recherche clinique, épidémiologique et essais thérapeutiques (CRECET), faculté de médecine et pharmacie, Rabat, Maroc.
authors.forename: Ali
authors.initials: A
authors.lastname: Benomar
authors.affiliation: Laboratoire de biostatistique, recherche clinique et épidémiologie (LBRCE), faculté de médecine et de pharmacie, université Mohamed V, Rabat, Maroc.
authors.forename: Redouan
authors.initials: R
authors.lastname: Abouqal
authors.affiliation: Laboratoire d'anatomie cytologie pathologiques, faculté de médecine et de pharmacie, université Mohamed V, hôpital d'enfants, Rabat, Maroc.
authors.forename: Zaitouna
authors.initials: Z
authors.lastname: Alhamany
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000473:pathology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007249:Inflammation; D007668:Kidney / Q000473:pathology*; D007674:Kidney Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009018:Morocco; D058225:Plaque, Amyloid
keywords: AA amyloidosis; Amyloid deposit; Amylose AA; Chronic infections; Dépôts d’amylose; Maladies infectieuses