title: Anal Douche Practices and Willingness to Use a Rectal Microbicide Enema for HIV Prevention and Associated Factors Among an Internet Sample of HIV-Negative and HIV-Discordant Male Couples in the US.
abstract: A significant proportion of MSM acquire HIV from their primary relationship partners. Rectal microbicides are currently being studied to determine their efficacy for HIV prevention, yet willingness to use rectal microbicides among male couples is largely unknown. Dyadic data from 333 HIV-negative and HIV-discordant male couples, representing 631 HIV-negative men, were used to assess anal douching practices and willingness to use a rectal microbicide for HIV prevention. 17 % of men douched 100 % of the time before having anal sex within their primary partner. Among those who had sex outside of their relationship, 36 % had douched 100 % of the time before having anal sex with a casual MSM partner. Most men (63 %) indicated a willingness to use a theoretically effective rectal microbicide prior to anal sex for HIV prevention. If found effective, rectal microbicides delivered as an anal douche may be an acceptable format for HIV prevention to some MSM who already engage in anal douching. Understanding current douching practices will be important in successfully promoting the uptake of rectal microbicides.
authors.affiliation: Department of Public Health Sciences, University of Miami Miller School of Medicine, 1120 N.W. 14th Street, Suite 1021, Miami, FL, 33136, USA. jwm35@med.miami.edu.
authors.forename: Jason W
authors.initials: JW
authors.lastname: Mitchell
authors.affiliation: Department of Public Health Sciences, University of Miami Miller School of Medicine, 1120 N.W. 14th Street, Suite 1021, Miami, FL, 33136, USA.
authors.forename: Amber I
authors.initials: AI
authors.lastname: Sophus
authors.affiliation: Department of Public Health Sciences, University of Miami Miller School of Medicine, 1120 N.W. 14th Street, Suite 1021, Miami, FL, 33136, USA.
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Division of Infectious Diseases, Center for AIDS Intervention Research, Medical College of Wisconsin, Milwaukee, WI, USA.
authors.forename: Andrew E
authors.initials: AE
authors.lastname: Petroll
mesh_terms: D000285:Administration, Rectal; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D004733:Enema; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D018451:Homosexuality, Male / Q000523:psychology / Q000706:statistics & numerical data*; D006801:Humans; D020407:Internet; D008297:Male; D010342:Patient Acceptance of Health Care; D012725:Sexual Behavior / Q000523:psychology / Q000706:statistics & numerical data*; D012747:Sexual Partners; D007507:Therapeutic Irrigation; D047568:Unsafe Sex / Q000706:statistics & numerical data*
chemical_list: D000890:Anti-Infective Agents
keywords: Douche; Enema; HIV prevention; Male couples; Microbicide willingness