title: Surgical management of osteonecrosis of the femoral head in patients with sickle cell disease.
abstract: Sickle cell disease is a known risk factor for osteonecrosis of the hip. Necrosis within the femoral head may cause severe pain, functional limitations, and compromise quality of life in this patient population. Early stages of avascular necrosis of the hip may be managed surgically with core decompression with or without autologous bone grafting. Total hip arthroplasty is the mainstay of treatment of advanced stages of the disease in patients who have intractable pain and are medically fit to undergo the procedure. The management of hip pathology in sickle cell disease presents numerous medical and surgical challenges, and the careful perioperative management of patients is mandatory. Although there is an increased risk of medical and surgical complications in patients with sickle cell disease, total hip arthroplasty can provide substantial relief of pain and improvement of function in the appropriately selected patient.
authors.affiliation: Atul F Kamath, Michael H McGraw, Craig L Israelite, Department of Orthopedic Surgery, the Center for Hip Preservation, Penn Medicine, University of Pennsylvania, Philadelphia, PA 19107, United States.
authors.forename: Atul F
authors.initials: AF
authors.lastname: Kamath
authors.affiliation: Atul F Kamath, Michael H McGraw, Craig L Israelite, Department of Orthopedic Surgery, the Center for Hip Preservation, Penn Medicine, University of Pennsylvania, Philadelphia, PA 19107, United States.
authors.forename: Michael H
authors.initials: MH
authors.lastname: McGraw
authors.affiliation: Atul F Kamath, Michael H McGraw, Craig L Israelite, Department of Orthopedic Surgery, the Center for Hip Preservation, Penn Medicine, University of Pennsylvania, Philadelphia, PA 19107, United States.
authors.forename: Craig L
authors.initials: CL
authors.lastname: Israelite
keywords: Avascular necrosis; Core decompression; Hip; Orthopedic; Osteonecrosis; Sickle cell disease; Total hip arthroplasty