title: Response mode-dependent differences in neurofunctional networks during response inhibition: an EEG-beamforming study.
abstract: Response inhibition processes are one of the most important executive control functions and have been subject to intense research in cognitive neuroscience. However, knowledge on the neurophysiology and functional neuroanatomy on response inhibition is biased because studies usually employ experimental paradigms (e.g., sustained attention to response task, SART) in which behavior is susceptible to impulsive errors. Here, we investigate whether there are differences in neurophysiological mechanisms and networks depending on the response mode that predominates behavior in a response inhibition task. We do so comparing a SART with a traditionally formatted task paradigm. We use EEG-beamforming in two tasks inducing opposite response modes during action selection. We focus on theta frequency modulations, since these are implicated in cognitive control processes. The results show that a response mode that is susceptible to impulsive errors (response mode used in the SART) is associated with stronger theta band activity in the left temporo-parietal junction. The results suggest that the response modes applied during response inhibition differ in the encoding of surprise signals, or related processes of attentional sampling. Response modes during response inhibition seem to differ in processes necessary to update task representations relevant to behavioral control.
authors.affiliation: Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Dippel
authors.affiliation: Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany.
authors.forename: Witold
authors.initials: W
authors.lastname: Chmielewski
authors.affiliation: Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany.
authors.forename: Moritz
authors.initials: M
authors.lastname: Mückschel
authors.affiliation: Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Schubertstrasse 42, 01309, Dresden, Germany. christian.beste@uniklinikum-dresden.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Beste
mesh_terms: D000328:Adult; D001288:Attention / Q000502:physiology; D002540:Cerebral Cortex / Q000502:physiology*; D004569:Electroencephalography; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000502:physiology; D007266:Inhibition, Psychological; D008297:Male; D009483:Neuropsychological Tests; D011597:Psychomotor Performance; D012815:Signal Processing, Computer-Assisted; D013826:Theta Rhythm; D055815:Young Adult
keywords: Beamforming; EEG; Response inhibition; Temporo-parietal junction; Theta frequency