title: Greater sensitivity of the cortical face processing system to perceptually-equated face detection.
abstract: Face detection, the perceptual capacity to identify a visual stimulus as a face before probing deeper into specific attributes (such as its identity or emotion), is essential for social functioning. Despite the importance of this functional capacity, face detection and its underlying brain mechanisms are not well understood. This study evaluated the roles that the cortical face processing system, which is identified largely through studying other aspects of face perception, play in face detection. Specifically, we used functional magnetic resonance imaging (fMRI) to examine the activations of the fusifom face area (FFA), occipital face area (OFA) and superior temporal sulcus (STS) when face detection was isolated from other aspects of face perception and when face detection was perceptually-equated across individual human participants (n=20). During face detection, FFA and OFA were significantly activated, even for stimuli presented at perceptual-threshold levels, whereas STS was not. During tree detection, however, FFA and OFA were responsive only for highly salient (i.e., high contrast) stimuli. Moreover, activation of FFA during face detection predicted a significant portion of the perceptual performance levels that were determined psychophysically for each participant. This pattern of result indicates that FFA and OFA have a greater sensitivity to face detection signals and selectively support the initial process of face vs. non-face object perception.
authors.affiliation: McLean Hospital, Department of Psychiatry, Harvard Medical School, United States.
authors.forename: S
authors.initials: S
authors.lastname: Maher
authors.affiliation: McLean Hospital, Department of Psychiatry, Harvard Medical School, United States.
authors.forename: T
authors.initials: T
authors.lastname: Ekstrom
authors.affiliation: McLean Hospital, Department of Psychiatry, Harvard Medical School, United States.
authors.forename: Y
authors.initials: Y
authors.lastname: Tong
authors.affiliation: McLean Hospital, Department of Psychiatry, Harvard Medical School, United States.
authors.forename: L D
authors.initials: LD
authors.lastname: Nickerson
authors.affiliation: McLean Hospital, Department of Psychiatry, Harvard Medical School, United States.
authors.forename: B
authors.initials: B
authors.lastname: Frederick
authors.affiliation: McLean Hospital, Department of Psychiatry, Harvard Medical School, United States. Electronic address: ychen@mclean.harvard.edu.
authors.forename: Y
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D003071:Cognition / Q000502:physiology; D004644:Emotions / Q000502:physiology; D005145:Face / Q000502:physiology; D000066499:Facial Recognition / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe / Q000502:physiology; D010775:Photic Stimulation; D011601:Psychophysics; D012931:Social Environment; D013702:Temporal Lobe / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*
keywords: Cognition; Facial; Perception; Vision; Visual; fMRI