title: [CHANGE OF ANTICOAGULANT EFFECT OF RIVAROXABAN DURING A DAY].
abstract: The article presents an assessment of anticoagulant effect of rivaroxaban in 35 patients with thromboembolic diseases. The results of expressed anticoagulant effect of rivaroxaban were obtained during a day (or more). The data of increase in sensitivity to thrombomodulin indicated about work enchancement of protein C system against the background of rivaroxaban therapy.
authors.forename: I V
authors.initials: IV
authors.lastname: Gel'tser
authors.forename: O A
authors.initials: OA
authors.lastname: Smirnova
authors.forename: O Yu
authors.initials: OY
authors.lastname: Matvienko
authors.forename: O G
authors.initials: OG
authors.lastname: Golovina
authors.forename: L P
authors.initials: LP
authors.lastname: Papayan
mesh_terms: D000328:Adult; D000368:Aged; D001777:Blood Coagulation / Q000187:drug effects*; D002940:Circadian Rhythm; D004305:Dose-Response Relationship, Drug; D065427:Factor Xa Inhibitors / Q000493:pharmacokinetics / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069552:Rivaroxaban / Q000008:administration & dosage / Q000493:pharmacokinetics*; D013918:Thrombin Time; D013923:Thromboembolism / Q000097:blood / Q000517:prevention & control*
chemical_list: D065427:Factor Xa Inhibitors; D000069552:Rivaroxaban