title: Draft genome sequence of Janthinobacterium lividum strain MTR reveals its mechanism of capnophilic behavior.
abstract: Janthinobacterium lividum is a Gram-negative bacterium able to produce violacein, a pigment with antimicrobial and antitumor properties. Janthinobacterium lividum colonizes the skin of some amphibians and confers protection against fungal pathogens. The mechanisms underlying this association are not well understood. In order to identify the advantages for the bacterium to colonize amphibian skin we sequenced Janthinobacterium lividum strain MTR, a strain isolated from Cajón del Maipo, Chile. The strain has capnophilic behavior, with growth favored by high concentrations (5 %) of carbon dioxide. Its genome is 6,535,606 bp in size, with 5,362 coding sequences and a G + C content of 62.37 %. The presence of genes encoding for products that participate in the carbon fixation pathways (dark CAM pathways), and the entire set of genes encoding for the enzymes of the glyoxylate cycle may explain the capnophilic behavior and allow us to propose that the CO2 secreted by the skin of amphibians is the signal molecule that guides colonization by Janthinobacterium lividum.
authors.affiliation: Unidad de Apoyo Bioinformático, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Alameda, 3363 Santiago, Chile.
authors.forename: Natalia
authors.initials: N
authors.lastname: Valdes
authors.affiliation: Laboratorio de Metagenómica Bacteriana, Centro de Biotecnología Acuícola, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Alameda, 3363 Santiago, Chile.
authors.forename: Paola
authors.initials: P
authors.lastname: Soto
authors.affiliation: Laboratorio de Virología de Hongos, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Alameda, 3363 Santiago, Chile.
authors.forename: Luis
authors.initials: L
authors.lastname: Cottet
authors.affiliation: Laboratorio de Metagenómica Bacteriana, Centro de Biotecnología Acuícola, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Alameda, 3363 Santiago, Chile.
authors.forename: Paula
authors.initials: P
authors.lastname: Alarcon
authors.affiliation: Laboratorio de Microbiología Ambiental y Extremófilos, Departamento de Ciencias Biológicas y Biodiversidad, Universidad de los Lagos, Fuchslocher, 1305 Osorno, Chile.
authors.forename: Alex
authors.initials: A
authors.lastname: Gonzalez
authors.affiliation: Laboratorio de Virología de Hongos, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Alameda, 3363 Santiago, Chile.
authors.forename: Antonio
authors.initials: A
authors.lastname: Castillo
authors.affiliation: Centro de Investigación Biomédica, Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, El Llano Subercaseaux, 2801 Santiago, Chile ; Universidad Científica del Sur, Panamericana Sur Km. 19, Lima, Perú
authors.forename: Gino
authors.initials: G
authors.lastname: Corsini
authors.affiliation: Laboratorio de Metagenómica Bacteriana, Centro de Biotecnología Acuícola, Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Alameda, 3363 Santiago, Chile.
authors.forename: Mario
authors.initials: M
authors.lastname: Tello
keywords: Capnophilic; Carbon dioxide; Carbon fixation; Janthinobacterium lividum; Violacein