title: Screening neonatal jaundice based on the sclera color of the eye using digital photography.
abstract: A new screening technique for neonatal jaundice is proposed exploiting the yellow discoloration in the sclera. It involves taking digital photographs of newborn infants' eyes (n = 110) and processing the pixel colour values of the sclera to predict the total serum bilirubin (TSB) levels. This technique has linear and rank correlation coefficients of 0.75 and 0.72 (both p<0.01) with the measured TSB. The mean difference ( ± SD) is 0.00 ± 41.60 µmol/l. The receiver operating characteristic curve shows that this technique can identify subjects with TSB above 205 µmol/l with sensitivity of 1.00 and specificity of 0.50, showing its potential as a screening device.
authors.affiliation: Department of Medical Physics & Biomedical Engineering, University College London, UK.
authors.forename: Terence S
authors.initials: TS
authors.lastname: Leung
authors.affiliation: Department of Medical Physics & Biomedical Engineering, University College London, UK.
authors.forename: Karan
authors.initials: K
authors.lastname: Kapur
authors.affiliation: Department of Medical Physics & Biomedical Engineering, University College London, UK.
authors.forename: Ashley
authors.initials: A
authors.lastname: Guilliam
authors.affiliation: The Neonatal Care Unit, Elizabeth Garrett Anderson Wing, University College London Hospitals Trust, UK.
authors.forename: Jade
authors.initials: J
authors.lastname: Okell
authors.affiliation: The Neonatal Care Unit, Elizabeth Garrett Anderson Wing, University College London Hospitals Trust, UK.
authors.forename: Bee
authors.initials: B
authors.lastname: Lim
authors.affiliation: Department of Civil, Environmental & Geomatic Engineering, University College London, UK.
authors.forename: Lindsay W
authors.initials: LW
authors.lastname: MacDonald
authors.affiliation: The Neonatal Care Unit, Elizabeth Garrett Anderson Wing, University College London Hospitals Trust, UK.
authors.forename: Judith
authors.initials: J
authors.lastname: Meek
keywords: (300.6550) Spectroscopy, visible; (330.1710) Color, measurement