title: A novel biocompatible europium ligand for sensitive time-gated immunodetection.
abstract: We describe the synthesis of a novel hydrophilic derivative of a tetradentate β-diketone europium ligand that was used to prepare an immunoconjugate probe against Giardia lamblia cysts. We used a Gated Autosynchronous Luminescence Detector (GALD) to obtain high quality delayed luminescence images of cells 30-fold faster than ever previously reported.
authors.affiliation: ARC Centre of Excellence for Nanoscale Biophotonics (CNBP), Macquarie University, Sydney, Australia. Nima.Sayyadi@mq.edu.au and Department of Chemistry and Biomolecular Sciences Macquarie University, Sydney, Australia.
authors.forename: Nima
authors.initials: N
authors.lastname: Sayyadi
authors.affiliation: Department of Physics and Astronomy, Macquarie University Sydney, Australia.
authors.forename: Russell E
authors.initials: RE
authors.lastname: Connally
authors.affiliation: Department of Chemistry and Biomolecular Sciences Macquarie University, Sydney, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Try
mesh_terms: D001672:Biocompatible Materials; D005063:Europium / Q000737:chemistry*; D008024:Ligands; D057230:Limit of Detection
chemical_list: D001672:Biocompatible Materials; D008024:Ligands; D005063:Europium