title: Cerebellar Degeneration as a Rare Paraneoplastic Syndrome in a Child With Hodgkin Lymphoma.
abstract: We report a rare case of cerebellar degeneration as a paraneoplastic syndrome in an 8-year-old boy with Hodgkin lymphoma that presented during first-line treatment. Antibodies against Purkinje cells (anti-Tr antibodies) were detected in the serum of the patient. After successful treatment of the lymphoma, the cerebellar symptoms resolved partially. Childhood presentation of paraneoplastic cerebellar degeneration is extremely rare, with only a few reports in the literature. For this reason, the description of all such cases contributes to the enrichment of the medical knowledge and will improve the diagnosis and the treatment of this complication.
authors.affiliation: *Specialized Hospital for Pediatric Oncohaematology †Multispecialty Hospitals for Active Treatment in Neurology and Psychiatry "Saint Naum", Sofia, Bulgaria.
authors.forename: Boryana E
authors.initials: BE
authors.lastname: Avramova
authors.forename: Tanya
authors.initials: T
authors.lastname: Hristova
authors.forename: Maya
authors.initials: M
authors.lastname: Yordanova
authors.forename: Irena
authors.initials: I
authors.lastname: Vlahova
authors.forename: Albena
authors.initials: A
authors.lastname: Muchinova
authors.forename: Veneta
authors.initials: V
authors.lastname: Bojinova
authors.forename: Dobrin
authors.initials: D
authors.lastname: Konstantinov
mesh_terms: D002526:Cerebellar Diseases / Q000209:etiology*; D002648:Child; D006689:Hodgkin Disease / Q000150:complications* / Q000628:therapy; D006801:Humans; D008297:Male; D010257:Paraneoplastic Syndromes / Q000209:etiology*