title: Outcomes of wavefront-guided laser in situ keratomileusis using a new-generation Hartmann-Shack aberrometer in patients with high myopia.
abstract: OBJECTIVE
  To evaluate refractive and visual outcomes of wavefront-guided laser in situ keratomileusis (LASIK) to correct high myopia using a new Hartmann-Shack aberrometer.
  
  
  METHODS
  Optical Express, Glasgow, United Kingdom.
  
  
  METHODS
  Retrospective noncomparative case series.
  
  
  METHODS
  Data of eyes that had wavefront-guided LASIK for high myopia and myopic astigmatism (spherical equivalent [SE] between -6.00 diopters [D] and -10.25 D, up to 5.00 D of cylinder) were analyzed. The treatment profile was derived from a new-generation Hartmann-Shack aberrometer (iDesign Advanced Wavescan). Visual acuities, refractive outcomes, vector analysis of refractive cylinder, and patient satisfaction were assessed. Three-months data are presented.
  
  
  RESULTS
  Data were obtained for 621 eyes. The mean manifest SE reduced from -7.28 D ± 1.05 (SD) (range -10.25 to -6.00 D) preoperatively to -0.09 ± 0.44 D (range -2.13 to +1.38 D) at 3 months. The mean manifest cylinder changed from -1.02 ± 0.82 D (range -5.00 to 0.00 D) to -0.27 ± 0.33 D (range -1.75 to 0.00 D) postoperatively. The percentage of eyes achieving an uncorrected distance visual acuity 20/20 or better was 82.4% monocularly and 92.5% binocularly. The mean correction ratio of refractive cylinder was 1.02 ± 0.48, and the mean error of angle was -0.29 ± 14.56 degrees. A postoperative questionnaire revealed high satisfaction with the outcomes of the procedure, with low scores for night-vision phenomena.
  
  
  CONCLUSIONS
  The results in this study were promising in terms of safety, efficacy, and predictability in eyes with high degrees of myopia.
  
  
  BACKGROUND
  Dr. Schallhorn is a consultant to Abbott Medical Optics, Inc. No other author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the Department of Ophthalmology (Schallhorn), University of California, San Francisco, California, USA; Optical Express (Schallhorn, Venter, Hannan, Hettinger), Glasgow, United Kingdom. Electronic address: scschallhorn@yahoo.com.
authors.forename: Steven C
authors.initials: SC
authors.lastname: Schallhorn
authors.affiliation: From the Department of Ophthalmology (Schallhorn), University of California, San Francisco, California, USA; Optical Express (Schallhorn, Venter, Hannan, Hettinger), Glasgow, United Kingdom.
authors.forename: Jan A
authors.initials: JA
authors.lastname: Venter
authors.affiliation: From the Department of Ophthalmology (Schallhorn), University of California, San Francisco, California, USA; Optical Express (Schallhorn, Venter, Hannan, Hettinger), Glasgow, United Kingdom.
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Hannan
authors.affiliation: From the Department of Ophthalmology (Schallhorn), University of California, San Francisco, California, USA; Optical Express (Schallhorn, Venter, Hannan, Hettinger), Glasgow, United Kingdom.
authors.forename: Keith A
authors.initials: KA
authors.lastname: Hettinger
mesh_terms: D057128:Aberrometry / Q000295:instrumentation*; D000328:Adult; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D017060:Patient Satisfaction; D012029:Refraction, Ocular / Q000502:physiology; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult