title: The design-by-treatment interaction model: a unifying framework for modelling loop inconsistency in network meta-analysis.
abstract: In this note, we clarify and prove the claim made Higgins et al. () that the design-by-treatment interaction model contains all possible loop inconsistency models. This claim provides a strong argument for using the design-by-treatment interaction model to describe loop inconsistencies in network meta-analysis. © 2015 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd.
authors.affiliation: Biostatistics Unit, MRC, Cambridge, UK. daniel.jackson@mrc-bsu.cam.ac.uk.
authors.forename: Dan
authors.initials: D
authors.lastname: Jackson
authors.affiliation: Biostatistics Unit, MRC, Cambridge, UK.
authors.forename: Paul
authors.initials: P
authors.lastname: Boddington
authors.affiliation: Biostatistics Unit, MRC, Cambridge, UK.
authors.forename: Ian R
authors.initials: IR
authors.lastname: White
mesh_terms: D000465:Algorithms; D002986:Clinical Trials as Topic; D006801:Humans; D015203:Reproducibility of Results; D012107:Research Design; D013223:Statistics as Topic; D000071076:Network Meta-Analysis as Topic