title: Ready-to-Eat Cereal Consumption with Total and Cause-Specific Mortality: Prospective Analysis of 367,442 Individuals.
abstract: BACKGROUND
  Intakes of ready-to-eat cereal (RTEC) have been inversely associated with risk factors of chronic diseases such as cardiovascular disease (CVD), type 2 diabetes, and certain cancers; however, their relations with total and cause-specific mortality remain unclear.
  
  
  OBJECTIVE
  To prospectively assess the associations of RTEC intakes with all causes and disease-specific mortality risk.
  
  
  METHODS
  The study included 367,442 participants from the prospective National Institutes of Health (NIH)-AARP Diet and Health Study. Intakes of RTEC were assessed at baseline.
  
  
  RESULTS
  Over an average of 14 years of follow-up, 46,067 deaths were documented. Consumption of RTEC was significantly associated with reduced risk of mortality from all-cause mortality and death from CVD, diabetes, all cancer, and digestive cancer (all p for trend < 0.05). In multivariate models, compared to nonconsumers of RTEC, those in the highest intake of RTEC had a 15% lower risk of all-cause mortality and 10%-30% lower risk of disease-specific mortality. Within RTEC consumers, total fiber intakes were associated with reduced risk of mortality from all-cause mortality and deaths from CVD, all cancer, digestive cancer, and respiratory disease (all p for trend < 0.005).
  
  
  CONCLUSIONS
  Consumption of RTEC was associated with reduced risk of all-cause mortality and mortality from specific diseases such as CVD, diabetes, and cancer. This association may be mediated via greater fiber intake.
authors.affiliation: a Department of Nutrition, Harvard School of Public Health , Boston , Massachusetts.
authors.forename: Min
authors.initials: M
authors.lastname: Xu
authors.affiliation: a Department of Nutrition, Harvard School of Public Health , Boston , Massachusetts.
authors.forename: Tao
authors.initials: T
authors.lastname: Huang
authors.affiliation: b NutraSource , Royal Oak , Michigan.
authors.forename: Albert W
authors.initials: AW
authors.lastname: Lee
authors.affiliation: a Department of Nutrition, Harvard School of Public Health , Boston , Massachusetts.|c Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School , Boston , Massachusetts.
authors.forename: Lu
authors.initials: L
authors.lastname: Qi
authors.affiliation: b NutraSource , Royal Oak , Michigan.
authors.forename: Susan
authors.initials: S
authors.lastname: Cho
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000401:mortality*; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000401:mortality*; D004034:Diet Surveys; D002523:Edible Grain; D057140:Fast Foods; D005247:Feeding Behavior; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000453:epidemiology / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology / Q000401:mortality*; D011446:Prospective Studies; D014481:United States / Q000453:epidemiology
keywords: CVD; fiber; mortality; ready-to-eat cereals