title: [Adaptive clinical study methodologies in drug development].
abstract: The evolution of drug development in human, clinical phase studies triggers the overview of those technologies and procedures which are labelled as adaptive clinical trials. The most relevant procedural and operational aspects will be discussed in this overview from points of view of clinico-methodological aspect.
authors.affiliation: PAREXEL Magyarország Kft. Budapest, Hermina út 17., 1146.
authors.forename: János
authors.initials: J
authors.lastname: Antal
mesh_terms: D015415:Biomarkers; D035843:Biomedical Research / Q000379:methods* / Q000592:standards; D000068456:Clinical Studies as Topic / Q000379:methods* / Q000592:standards; D002986:Clinical Trials as Topic / Q000379:methods; D003661:Decision Support Techniques; D015195:Drug Design; D006801:Humans; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D012107:Research Design; D018401:Sample Size
chemical_list: D015415:Biomarkers
keywords: adaptive; adaptív; clinical study; drug development; gyógyszerfejlesztés; klinikai vizsgálat