title: End-tidal carbon dioxide monitoring may be associated with a higher possibility of return of spontaneous circulation during out-of-hospital cardiac arrest: a population-based study.
abstract: BACKGROUND
  During cardiac arrest, end-tidal carbon dioxide (ETCO2) monitoring is recommended as a chest compression performance indicator. However, its frequency of use during out-of-hospital cardiac arrest (OHCA) and its benefits have never been evaluated in real clinical situations.
  
  
  OBJECTIVE
  We investigated OHCA patients in Taiwan to evaluate the frequency of ETCO2 monitoring and its effects on sustained return of spontaneous circulation (ROSC).
  
  
  METHODS
  We sampled the Taiwan National Health Insurance claims database, which contains 1 million beneficiaries. All adult beneficiaries older than 18 years who presented with OHCA and received chest compression between 1 January 2005 and 31 December 2012 were enrolled. We further identified patients with ETCO2 monitoring and matched each 1 with 20 patients who did not receive ETCO2 monitoring based on their propensity scores. A simple conditional logistic regression model was applied to compare the odds ratio (OR) for sustained ROSC in the matched cohorts.
  
  
  RESULTS
  A total of 5041 OHCA patients were enrolled. The frequency of ETCO2 monitoring has increased since 2010 but still is low. After matching, 53 patients with ETCO2 monitoring and 1060 without ETCO2 monitoring were selected. The OR of sustained ROSC in the ETCO2 group was significantly increased (2.38, 95 % CI 1.28-4.42).
  
  
  CONCLUSIONS
  Patients who received ETCO2 monitoring during OHCA had a higher possibility of sustained ROSC, but the overall use of ETCO2 monitoring is still low despite strong recommendations for its use.
authors.affiliation: School of Medicine, Tzu Chi University, Hualien, Taiwan.|Emergency Department, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 2, Minsheng Rd., Dalin Township, Chiayi County 622, Taiwan, R.O.C.
authors.forename: Jiun-Jia
authors.initials: JJ
authors.lastname: Chen
authors.affiliation: School of Medicine, Tzu Chi University, Hualien, Taiwan.|Emergency Department, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 2, Minsheng Rd., Dalin Township, Chiayi County 622, Taiwan, R.O.C.
authors.forename: Yi-Kung
authors.initials: YK
authors.lastname: Lee
authors.affiliation: Emergency Department, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
authors.forename: Sheng-Wen
authors.initials: SW
authors.lastname: Hou
authors.affiliation: Department of Emergency Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Ming-Yuan
authors.initials: MY
authors.lastname: Huang
authors.affiliation: Department of Public Heath, National Taiwan University, Taipei, Taiwan.
authors.forename: Chen-Yang
authors.initials: CY
authors.lastname: Hsu
authors.affiliation: School of Medicine, Tzu Chi University, Hualien, Taiwan. drsu119@gmail.com.|Emergency Department, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 2, Minsheng Rd., Dalin Township, Chiayi County 622, Taiwan, R.O.C.. drsu119@gmail.com.
authors.forename: Yung-Cheng
authors.initials: YC
authors.lastname: Su
mesh_terms: D000328:Adult; D000368:Aged; D019296:Capnography / Q000379:methods*; D016887:Cardiopulmonary Resuscitation; D006801:Humans; D008875:Middle Aged; D058687:Out-of-Hospital Cardiac Arrest / Q000503:physiopathology*; D011237:Predictive Value of Tests; D057216:Propensity Score; D013624:Taiwan; D013990:Tidal Volume / Q000502:physiology