title: A Randomized Controlled Trial Translating the Diabetes Prevention Program to a University Worksite, Ohio, 2012-2014.
abstract: BACKGROUND
  Working adults spend much time at the workplace, an ideal setting for wellness programs targeting weight loss and disease prevention. Few randomized trials have evaluated the efficacy of worksite diabetes prevention programs. This study evaluated the efficacy of a worksite lifestyle intervention on metabolic and behavioral risk factors compared with usual care.
  
  
  METHODS
  A pretest-posttest control group design with 3-month follow-up was used. Participants with prediabetes were recruited from a university worksite and randomized to receive a 16-week lifestyle intervention (n = 35) or usual care (n = 34). Participants were evaluated at baseline, postintervention, and 3-month follow-up. Dietary intake was measured by a food frequency questionnaire and level of physical activity by accelerometers. Repeated measures analysis of variance compared the change in outcomes between and within groups.
  
  
  RESULTS
  Mean (standard error [SE]) weight loss was greater in the intervention (-5.5% [0.6%]) than in the control (-0.4% [0.5%]) group (P < .001) postintervention and was sustained at 3-month follow-up (P < .001). Mean (SE) reductions in fasting glucose were greater in the intervention (-8.6 [1.6] mg/dL) than in the control (-3.7 [1.6] mg/dL) group (P = .02) postintervention; both groups had significant glucose reductions at 3-month follow-up (P < .001). In the intervention group, the intake of total energy and the percentage of energy from all fats, saturated fats, and trans fats decreased, and the intake of dietary fiber increased (all P < .01) postintervention.
  
  
  CONCLUSIONS
  The worksite intervention improved metabolic and behavioral risk factors among employees with prediabetes. The long-term impact on diabetes prevention and program sustainability warrant further investigation.
authors.affiliation: The Ohio State University, Columbus, Ohio.
authors.forename: Kellie R
authors.initials: KR
authors.lastname: Weinhold
authors.affiliation: The Ohio State University, 1787 Neil Ave, 325 Campbell Hall, Columbus, OH 43210. Email: miller.4453@osu.edu.
authors.forename: Carla K
authors.initials: CK
authors.lastname: Miller
authors.affiliation: Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: David G
authors.initials: DG
authors.lastname: Marrero
authors.affiliation: The Ohio State University, Columbus, Ohio.
authors.forename: Haikady N
authors.initials: HN
authors.lastname: Nagaraja
authors.affiliation: The Ohio State University, Columbus, Ohio.
authors.forename: Brian C
authors.initials: BC
authors.lastname: Focht
authors.affiliation: The Ohio State University Health Plan, Inc, Columbus, Ohio.
authors.forename: Gregg M
authors.initials: GM
authors.lastname: Gascon
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control*; D005247:Feeding Behavior; D005260:Female; D005951:Glucose Tolerance Test; D006293:Health Promotion / Q000379:methods*; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009820:Ohio; D011236:Prediabetic State / Q000175:diagnosis*; D015397:Program Evaluation; D012307:Risk Factors; D014495:Universities; D015431:Weight Loss; D017132:Workplace