title: Secondary Vitreoretinal Lymphoma Masquerading as Acute Retinal Necrosis.
abstract: Intraocular lymphoma is considered a uveitis masquerade syndrome and may rarely present with features resembling a necrotizing viral retinitis. The authors report a secondary vitreoretinal lymphoma presenting in this fashion, which was treated with a unique combination of intravitreal methotrexate and rituximab.
authors.forename: Martha E
authors.initials: ME
authors.lastname: Ryan
authors.forename: Jessica G
authors.initials: JG
authors.lastname: Shantha
authors.forename: Hans E
authors.initials: HE
authors.lastname: Grossniklaus
authors.forename: Steven
authors.initials: S
authors.lastname: Yeh
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000378:metabolism; D003937:Diagnosis, Differential; D005134:Eye Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007278:Injections, Spinal; D058449:Intravitreal Injections; D008207:Lymphatic Metastasis; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000378:metabolism; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis*; D019572:Retinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary; D000069283:Rituximab / Q000008:administration & dosage; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D041623:Tomography, Optical Coherence; D014822:Vitreous Body / Q000187:drug effects / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; D000069283:Rituximab; D008727:Methotrexate