title: Cardiac Resynchronization Therapy in Women.
abstract: The benefits of cardiac resynchronization therapy (CRT) on the outcomes of patients with heart failure are unquestionable. Women are under-represented in all CRT studies. Most of the available data show that CRT produces a greater clinical benefit in women than men. In several studies, women have left bundle branch block more frequently than men. Women have a remarkably high (90%) CRT response over a wide range of QRS lengths (130-175 milliseconds). Use of a QRS duration of 150 milliseconds as the threshold for CRT prescription may deny a life-saving therapy to many women likely to benefit from CRT.
authors.affiliation: Advocate Heart Institute, Edward Heart Hospital, 4th Floor, 801 South Washington Street, Naperville, IL 60566, USA. Electronic address: mariarosa.Costanzo@advocatehealth.com.
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Costanzo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002037:Bundle-Branch Block / Q000401:mortality*; D058406:Cardiac Resynchronization Therapy / Q000401:mortality*; D015897:Comorbidity; D016757:Death, Sudden, Cardiac / Q000453:epidemiology* / Q000517:prevention & control; D019317:Evidence-Based Medicine; D005260:Female; D006333:Heart Failure / Q000401:mortality* / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012727:Sex Characteristics; D015996:Survival Rate; D016896:Treatment Outcome; D016387:Women's Health / Q000706:statistics & numerical data*
keywords: Cardiac resynchronization therapy; Heart failure; Left bundle branch block; Women