title: Sagitol D, a New Thiazole Containing Pyridoacridine Alkaloid from a Vietnamese Ascidian.
abstract: A new thiazole containing pyridoacridine alkaloid, named sagitol D (1), and five known alkaloids kuanoniaminesA (2), C (3), D (4), E (5), and F (6), have been isolated from an unidentified Vietnamese ascidian. The structure of the new compound was established from NMR spectroscopic data. Kuanoniamines C, D, E, and F showed moderate antioxidant activity in the DPPH (IC50 36 µM) and ABTS assays (TE = 0.5), while sagitol D showed weak activity (IC50 92 M;TE = 0.10), and kuanoniamine A was inactive.
authors.forename: Natalia K
authors.initials: NK
authors.lastname: Utkina
mesh_terms: D000166:Acridines / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry*; D000818:Animals; D015394:Molecular Structure; D010618:Phenanthrolines / Q000737:chemistry*; D013844:Thiazoles / Q000737:chemistry*; D014561:Urochordata / Q000737:chemistry*; D014744:Vietnam
chemical_list: D000166:Acridines; D000470:Alkaloids; D010618:Phenanthrolines; D013844:Thiazoles; C475900:pyridoacridine; C000603644:sagitol D