title: Expression of AmGR10 of the Gustatory Receptor Family in Honey Bee Is Correlated with Nursing Behavior.
abstract: We investigated the association between the expression of a gene encoding gustatory receptor (G10) and division of labor in the honey bee, Apis mellifera. Among 10 GR genes encoding proteins 15% ~ 99% amino acid identity in the honey bee, we found that AmGR10 with 99% identity is involved in nursing or brood care. Expression of AmGR10 was restricted to organs of the hypopharyngeal gland, brain, and ovary in the nurse bee phase. Members of an extended nursing caste under natural conditions continued to express this gene. RNAi knockdown of AmGR10 accelerated the transition to foraging. Our findings demonstrate that this one gene has profound effects on the division of labor associated with the development and physiology of honeybee society.
authors.affiliation: The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, Japan.
authors.forename: Yisilahaiti
authors.initials: Y
authors.lastname: Paerhati
authors.affiliation: Organization for Research Promotion, Iwate University, Morioka, Iwate, Japan.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Ishiguro
authors.affiliation: Organization for Research Promotion, Iwate University, Morioka, Iwate, Japan.
authors.forename: Risa
authors.initials: R
authors.lastname: Ueda-Matsuo
authors.affiliation: The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, Japan.
authors.forename: Ping
authors.initials: P
authors.lastname: Yang
authors.affiliation: The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, Japan.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Yamashita
authors.affiliation: The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate, Japan.
authors.forename: Kikukatsu
authors.initials: K
authors.lastname: Ito
authors.affiliation: Biochemical Science Association, Shinagawa-ku, Tokyo, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Maekawa
authors.affiliation: Institute for Bee Products and Health Science, Yamada Apiculture Center, Inc., Kagamino, Okayama, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Tani
authors.affiliation: Organization for Research Promotion, Iwate University, Morioka, Iwate, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Suzuki
mesh_terms: D000818:Animals; D001516:Bees / Q000235:genetics* / Q000254:growth & development; D001522:Behavior, Animal; D001921:Brain / Q000378:metabolism; D029721:Drosophila Proteins / Q000235:genetics; D005786:Gene Expression Regulation / Q000235:genetics*; D008969:Molecular Sequence Data; D011956:Receptors, Cell Surface / Q000096:biosynthesis* / Q000235:genetics; D015398:Signal Transduction
chemical_list: D029721:Drosophila Proteins; D011956:Receptors, Cell Surface; C405956:gustatory receptor, Drosophila