title: Staple Fixation Against Adhesive Fixation in Laparoscopic Inguinal Hernia Repair: A Meta-Analysis of Randomized Controlled Trials.
abstract: OBJECTIVE
  The aim of this article was to compare the outcomes of tissue adhesive fixation and the staple fixation of meshes in laparoscopic inguinal hernia repair.
  
  
  METHODS
  A systematic literature review was undertaken to identify studies that compare adhesive fixation and staple fixation of meshes in laparoscopic inguinal hernia repair.
  
  
  RESULTS
  The present meta-analysis pooled the effects of outcomes of a total of 1228 patients enrolled into 8 randomized controlled trials. Tissue adhesive fixation of the mesh was associated with less chronic postoperative pain after laparoscopic inguinal hernia repair compared with staple fixation (risk difference=-0.06; 95% confidence interval, -0.08, -0.04). However, statistically, there was no significant difference in the incidence of acute postoperative pain, recurrence, hematoma/seroma, and wound infection.
  
  
  CONCLUSIONS
  The use of the tissue adhesive fixation method reduces the incidence of chronic postoperative pain after laparoscopic inguinal hernia repair, and without any changes in the other outcomes.
authors.affiliation: Department of General Surgery, Affiliated to Zhong-Da Hospital, Southeast University, Nanjing, P.R. China.
authors.forename: Junsheng
authors.initials: J
authors.lastname: Li
authors.forename: Zhenling
authors.initials: Z
authors.lastname: Ji
authors.forename: Weiyu
authors.initials: W
authors.lastname: Zhang
mesh_terms: D006552:Hernia, Inguinal / Q000601:surgery*; D059685:Herniorrhaphy; D006801:Humans; D010535:Laparoscopy; D016032:Randomized Controlled Trials as Topic; D013526:Surgical Mesh; D017792:Surgical Stapling; D014014:Tissue Adhesives
chemical_list: D014014:Tissue Adhesives