title: Restless Legs Syndrome After Single Low Dose Quetiapine Administration.
abstract: Restless legs syndrome is an underdiagnosed sensori-motor disorder and psychotropic drugs are one of the main secondary causes of the illness. The most common psychotropic agents that cause restless legs syndrome are antidepressants; however, antipsychotics have also been reported to induce restless legs syndrome. The prevalence, vulnerability factors and the underlying mechanism of antipsychotic-induced restless legs syndrome are unclear. A possible explanation is that dopaminergic blockade is the main precipitator of the syndrome. Quetiapine-induced restless legs syndrome is another point of interest because of its low binding to D2 receptors. We herein report the case of a restless legs syndrome that emerged after a single low dose quetiapine administration.
authors.affiliation: Department of Psychiatry, Istanbul Medical Faculty, Istanbul University, Millet Street, Capa. Fatih, Istanbul, Postal Code: 34730, Turkey. mordraneth@gmail.com.
authors.forename: Ahmet Z
authors.initials: AZ
authors.lastname: Soyata
authors.forename: Fahri
authors.initials: F
authors.lastname: Celebi
authors.forename: Lutfi I
authors.initials: LI
authors.lastname: Yargc
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D000069348:Quetiapine Fumarate / Q000009:adverse effects*; D012148:Restless Legs Syndrome / Q000139:chemically induced* / Q000175:diagnosis*
chemical_list: D014150:Antipsychotic Agents; D000069348:Quetiapine Fumarate