title: A diet enriched with Mugil cephalus processed roes modulates the tissue lipid profile in healthy rats: a biochemical and chemometric assessment.
abstract: The effect of a diet enriched with mullet bottarga on the lipid profile (total lipids, total cholesterol, unsaturated fatty acids, α-tocopherol, and hydroperoxides) of plasma, liver, kidney, brain, and perirenal adipose tissues of healthy rats was investigated. Rats fed a 10% bottarga enriched-diet for 5 days showed body weights and tissue total lipid and cholesterol levels similar to those of animals fed control diet. Univariate and multivariate results showed that bottarga enriched-diet modified the fatty acid profile in all tissues, except brain. Significant increases of n-3 PUFA, particularly EPA, were observed together with a 20:4 n-6 decrease in plasma, liver, and kidney. Perirenal adipose tissue showed a fat accumulation that reflected the diet composition. The overall data suggest that mullet bottarga may be considered as a natural bioavailable source of n-3 PUFA and qualify it as a traditional food product with functional properties and a potential functional ingredient for preparation of n-3 PUFA enriched foods.
authors.affiliation: Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Km 4.5 SS 554, 09042 Monserrato, CA, Italy. anrosa@unica.it.
authors.forename: A
authors.initials: A
authors.lastname: Rosa
authors.affiliation: Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Km 4.5 SS 554, 09042 Monserrato, CA, Italy. anrosa@unica.it.
authors.forename: A
authors.initials: A
authors.lastname: Atzeri
authors.affiliation: Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Km 4.5 SS 554, 09042 Monserrato, CA, Italy. anrosa@unica.it.
authors.forename: D
authors.initials: D
authors.lastname: Putzu
authors.affiliation: Department of Chemical and Geological Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4.5, 09042 Monserrato, Cagliari, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Scano
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry; D002784:Cholesterol / Q000032:analysis; D004032:Diet; D004281:Docosahexaenoic Acids / Q000032:analysis / Q000493:pharmacokinetics; D015118:Eicosapentaenoic Acid / Q000032:analysis / Q000493:pharmacokinetics; D005227:Fatty Acids / Q000032:analysis; D015525:Fatty Acids, Omega-3 / Q000493:pharmacokinetics; D007668:Kidney / Q000737:chemistry / Q000378:metabolism; D008055:Lipids / Q000032:analysis* / Q000097:blood; D008099:Liver / Q000737:chemistry / Q000378:metabolism; D008297:Male; D019083:Mediterranean Region; D010063:Ovum / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D023701:Smegmamorpha; D024502:alpha-Tocopherol / Q000032:analysis
chemical_list: D005227:Fatty Acids; D015525:Fatty Acids, Omega-3; D008055:Lipids; D004281:Docosahexaenoic Acids; D002784:Cholesterol; D015118:Eicosapentaenoic Acid; D024502:alpha-Tocopherol