title: Recent Developments in Oral Epithelial Dysplasia Grading: A Critical Appraisal.
abstract: The final goal of a histopathological examination is to access the course of the presenting lesion. Histopathology is considered the gold standard in segregating benign and malignant entities, but its use in grading oral epithelial dysplasia (OED) has been a constant debate. Interobserver agreement in most studies on OED has averaged between poor to fair. Application of molecular predictive model could solve the disagreement at the histopathological level. But, in order to conduct genetic analysis, it is vital to categorize the entities based on the current diagnostic gold standard, which in turn is histopathological grading. Thus, improvising the standard of histopathological grading would aid in formulating a much reliable molecular predictive model.(1).
authors.affiliation: Associate Professor Department of Oral Pathology and Microbiology Faculty of Dental Sciences MS Ramaiah University of Applied Sciences Bengaluru, Karnataka, India.
authors.forename: Shankargouda
authors.initials: S
authors.lastname: Patil
authors.affiliation: Professor and Head Department of Oral Pathology Faculty of Dental Sciences MS Ramaiah University of Applied Sciences Bengaluru, Karnataka India.
authors.forename: Roopa S
authors.initials: RS
authors.lastname: Rao
authors.affiliation: Postgraduate Student (Final Year) Department of Oral Pathology Faculty of Dental Sciences MS Ramaiah University of Applied Sciences Bengaluru, Karnataka India.
authors.forename: A Thirumal
authors.initials: AT
authors.lastname: Raj
mesh_terms: D002278:Carcinoma in Situ / Q000175:diagnosis*; D006801:Humans; D009061:Mouth Mucosa; D009062:Mouth Neoplasms / Q000175:diagnosis*; D011230:Precancerous Conditions / Q000145:classification / Q000175:diagnosis*