title: Epidemiology and factors associated with candidaemia following Clostridium difficile infection in adults within metropolitan Atlanta, 2009-2013.
abstract: We assessed prevalence of and risk factors for candidaemia following Clostridium difficile infection (CDI) using longitudinal population-based surveillance. Of 13 615 adults with CDI, 113 (0·8%) developed candidaemia in the 120 days following CDI. In a matched case-control analysis, severe CDI and CDI treatment with vancomycin + metronidazole were associated with development of candidaemia following CDI.
authors.affiliation: Epidemic Intelligence Service Centers for Disease Control and Prevention,Atlanta,GA,USA.
authors.forename: S
authors.initials: S
authors.lastname: Vallabhaneni
authors.affiliation: Georgia Emerging Infections Program,Atlanta,GA,USA.
authors.forename: O
authors.initials: O
authors.lastname: Almendares
authors.affiliation: Emory University School of Medicine,Department of Medicine,Atlanta,GA,USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Farley
authors.affiliation: Georgia Emerging Infections Program,Atlanta,GA,USA.
authors.forename: J
authors.initials: J
authors.lastname: Reno
authors.affiliation: Georgia Emerging Infections Program,Atlanta,GA,USA.
authors.forename: Z T
authors.initials: ZT
authors.lastname: Smith
authors.affiliation: Georgia Emerging Infections Program,Atlanta,GA,USA.
authors.forename: B
authors.initials: B
authors.lastname: Stein
authors.affiliation: Division of Healthcare Quality Promotion,National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention,Atlanta,GA,USA.
authors.forename: S S
authors.initials: SS
authors.lastname: Magill
authors.affiliation: Division of Foodborne Waterborne and Environmental Diseases,National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention,Atlanta,GA,USA.
authors.forename: R M
authors.initials: RM
authors.lastname: Smith
authors.affiliation: Division of Foodborne Waterborne and Environmental Diseases,National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention,Atlanta,GA,USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Cleveland
authors.affiliation: Division of Healthcare Quality Promotion,National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention,Atlanta,GA,USA.
authors.forename: F C
authors.initials: FC
authors.lastname: Lessa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002175:Candida / Q000502:physiology*; D058387:Candidemia / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D016022:Case-Control Studies; D016360:Clostridioides difficile / Q000502:physiology*; D003015:Clostridium Infections / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D005845:Georgia / Q000453:epidemiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D014640:Vancomycin / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole; D014640:Vancomycin
keywords: CDI treatment; Candidaemia; Clostridium difficile infection; co-infection; severe CDI