title: [The efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV].
abstract: OBJECTIVE
  To evaluate the efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV.
  
  
  METHODS
  A total of 63 patients diagnosed with sudden sensorineural hearing loss with BPPV were treated through OPD. Patients were divided into three groups: 20 cases in intratympanic dexamethasone injection as initial treatment (group A); 18 cases in systemic hormone therapy group (group B); 25 cases in intratympanic dexamethasone injection as salvage treatment (group C). In addition, routine drugs were used to all patients.
  
  
  RESULTS
  The overall effective rate of group A, B and C in hearing recovery was 60.0%, 38.9% and 48.0%, respectively: (1) No significant difference of hearing recovery was observed among three groups (P > 0.05); (2) A significant difference of hearing recovery was evidenced between group A and C (P < 0.05); (3) A significant difference of hearing recovery was evidenced between group A and C (P < 0.05); (4) No statistically significant difference was found in the hearing recovery between group B and C (P > 0.05).
  
  
  CONCLUSIONS
  Our data showed that intratympanic dexamethasone should be used as initial therapy for treating the moderate and severe sudden deafness with BPPV.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Zhou
authors.forename: Youjun
authors.initials: Y
authors.lastname: Yu
authors.forename: Yuanxin
authors.initials: Y
authors.lastname: Zhao
authors.forename: Yuejian
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhen
authors.initials: Z
authors.lastname: Liu
authors.forename: Qiuling
authors.initials: Q
authors.lastname: Liu
mesh_terms: D065635:Benign Paroxysmal Positional Vertigo / Q000150:complications*; D003907:Dexamethasone / Q000008:administration & dosage* / Q000627:therapeutic use*; D006319:Hearing Loss, Sensorineural / Q000150:complications / Q000188:drug therapy*; D003639:Hearing Loss, Sudden / Q000150:complications / Q000188:drug therapy*; D006320:Hearing Tests; D006801:Humans; D000069555:Injection, Intratympanic; D016879:Salvage Therapy; D016896:Treatment Outcome
chemical_list: D003907:Dexamethasone