title: Current Updates on Therapeutic Advances in the Management of Cardiovascular Diseases.
abstract: Despite the significant advances in the medical research and treatment methods, the rate of mortality associated with cardiovascular disease (CVD) is continuously rising and it remains the leading cause of death worldwide. There are several treatment methods for CVD and associated complications that have been considered till now. The current treatment methods cannot produce rapid cure, but could prevent or reduce the progression of this devastating disease. In the current article, we have summarized the use of various pharmacological agents viz. HMG-CoA reductase inhibitors (statins), antihypertensive, thrombolytic and anticoagulation agents that are currently being used for the management of CVD which targets different biochemical or molecular events. Based on our article, more research in this field is advocated which will provide the rapid and effective treatment methods in order to avoid fatal complications associated with CVD.
authors.forename: Nasimudeen R
authors.initials: NR
authors.lastname: Jabir
authors.forename: Ali Nasir
authors.initials: AN
authors.lastname: Siddiqui
authors.forename: Chelapram Kandy
authors.initials: CK
authors.lastname: Firoz
authors.forename: Ghulam Md
authors.initials: GM
authors.lastname: Ashraf
authors.forename: Syed Kashif
authors.initials: SK
authors.lastname: Zaidi
authors.forename: Mohd Shahnawaz
authors.initials: MS
authors.lastname: Khan
authors.forename: Shazi
authors.initials: S
authors.lastname: Shakil
authors.forename: Mohammed Nabil
authors.initials: MN
authors.lastname: Alama
authors.forename: Mohammad Amjad
authors.initials: MA
authors.lastname: Kamal
authors.affiliation: King Fahd Medical Research Center, King Abdulaziz University, P. O. Box 80216, Jeddah 21589, Saudi Arabia. shamstabrez1@gmail.com.
authors.forename: Shams
authors.initials: S
authors.lastname: Tabrez
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D019468:Disease Management; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*
chemical_list: D000925:Anticoagulants; D000959:Antihypertensive Agents; D005343:Fibrinolytic Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D006903:Hydroxymethylglutaryl CoA Reductases