title: Placental site trophoblastic tumor and choriocarcinoma: an unusual presentation.
abstract: BACKGROUND
  Mixed trophoblastic tumor composed of choriocarcinoma and placental site trophoblastic tumor was diagnosed on histopathology slides review, is a very rare mixed tumor and cured after adjuvant chemotherapy.
  
  
  METHODS
  Twenty-nine years old, Para 2 female presented with 4 months history of irregular vaginal bleeding after an uncomplicated vaginal delivery. Abdominal examination showed 14 weeks uterus with β-hCG level of 14,889 mIU/ml. Slides review confirmed the diagnosis of placental site trophoblastic tumor (PSTT). Patient underwent total abdominal hysterectomy and resection of anterior vaginal wall mass. Post operative (48 h) β-hCG level was 6016 mIU/ml. Final pathology showed mixed trophoblastic tumor composed of choriocarcinoma (CC) and PSTT. Adjuvant chemotherapy started and continued for three cycles after achieving normal β-hCG.
  
  
  CONCLUSIONS
  PSTT is a rare disease and potentially curable. Differential diagnosis in women presented with vaginal bleeding and a uterine mass in the post partum period must include gestational trophoblastic disease.
authors.affiliation: Department Of Obstetrics and Gynecology, College of Medicine, Umm Al-Qura University, PO Box : 6707, Makkah, Saudi Arabia. gari_umq@yahoo.com.
authors.forename: Abdulrahim
authors.initials: A
authors.lastname: Gari
mesh_terms: D000328:Adult; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D011247:Pregnancy; D018245:Trophoblastic Tumor, Placental Site / Q000175:diagnosis* / Q000601:surgery; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000601:surgery