title: Multifocal sclerosing angiomatoid nodular transformation of the spleen in a patient with simultaneous metachronous liver metastasis after colon cancer surgery: a first case report.
abstract: Sclerosing angiomatoid nodular transformation of the spleen (SANT) is a benign, extremely rare vascular lesion of the spleen with unknown pathogenesis. SANT is often discovered incidentally, and can sometimes be found in patients with a history of cancer. Based on absent definitive radiological signs and varying growth patterns, distinction from malignant processes such as metastasis can be very difficult. Therefore, surgical resection of the spleen is indicated in most cases of patients with history of cancer. We report a case of a bifocal manifestation of SANT in the spleen in a patient with history of colon cancer and newly-diagnosed metachronous liver metastases.
authors.forename: A K
authors.initials: AK
authors.lastname: Mueller
authors.forename: C
authors.initials: C
authors.lastname: Haane
authors.forename: K
authors.initials: K
authors.lastname: Lindner
authors.forename: P J
authors.initials: PJ
authors.lastname: Barth
authors.forename: N
authors.initials: N
authors.lastname: Senninger
authors.forename: R
authors.initials: R
authors.lastname: Hummel
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D003082:Colectomy; D003110:Colonic Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery*; D006498:Hepatectomy; D018219:Histiocytoma, Benign Fibrous / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D012086:Reoperation; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor