title: Effect of short term aerobic exercise on fasting and postprandial lipoprotein subfractions in healthy sedentary men.
abstract: BACKGROUND
  Our goal was to investigate the effect of short term exercise on fasting and postprandial lipoprotein profile.
  
  
  METHODS
  Healthy sedentary men exercised 20 min for four days. The intensity of exercise was modulated to maintain 75-80 % of a calculated HRmax. Before and after the exercise program, fasting and postprandial (4 h after standard meal) concentrations of lipoprotein subfractions were measured by an electrophoresis in polyacrylamide gel and total concentrations of TAG, LDL and HDL by enzymatic colorimetric method. After 2 days of rest, fasting and postprandial concentrations of lipoprotein fractions and subfractions were measured to determine a persistency of a changes in the lipoprotein profile.
  
  
  RESULTS
  4 days of physical exercise led to statistically significant decrease of concentration of triacylglycerol in fasting (76.29 ± 20.07, 53.92 ± 10.90, p < 0.05) and postprandial state (139.06 ± 23.72, 96.55 ± 25.21, p < 0.05) VLDL in fasting (21.88 ± 3.87, 18.00 ± 3.93, p < 0.05) and postprandial state (23.88 ± 3.52, 19.25 ± 3.62, p < 0.05), total cholesterol in fasting (162.26 ± 23.38, 148.91 ± 17.72, p < 0.05) and postprandial state (163.73 ± 23.02, 150.08 ± 18.11, p < 0.05). Atherogenic medium LDL decreased also in fasting (9.89 ± 3.27, 6.22 ± 2.55, p < 0.001) and postprandial state (8.88 ± 6.51, 6.88 ± 5.57, p < 0.001). However decrease of large IDL (25.38 ± 3.54, 23.88 ± 3.91, p < 0.05) and large LDL particles (42.89 ± 11.40, 38.67 ± 9.30) was observed only in postprandial state. Total HDL concentration remained unchanged but we observed statistically significant decrease of small HDL particles in fasting (6.11 ± 2.89, 4.22, p < 0.05) and postprandial state (6.44 ± 3.21, 4.56 ± 1.33, p < 0.05). Concentration of these particles are associated with progression of atherosclerosis. All changes of fasting and postprandial lipoprotein profile disappeared after 2 days of rest.
  
  
  CONCLUSIONS
  Just 4 daily settings of 20 min of physical exercise can lead to significant positive changes of fasting and postprandial lipoprotein profile.
authors.affiliation: 2nd Department of Internal Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic.
authors.forename: Peter
authors.initials: P
authors.lastname: Sabaka
authors.affiliation: 2nd Department of Internal Medicine, St. Anne's University Hospital and Masaryk University, Pekarska 53, 656 91, Brno, Czech Republic. kruzliakpeter@gmail.com.
authors.forename: Peter
authors.initials: P
authors.lastname: Kruzliak
authors.affiliation: 2nd Department of Internal Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic.
authors.forename: David
authors.initials: D
authors.lastname: Balaz
authors.affiliation: 2nd Department of Internal Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic.
authors.forename: Andrea
authors.initials: A
authors.lastname: Komornikova
authors.affiliation: 2nd Department of Internal Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic.
authors.forename: Denisa
authors.initials: D
authors.lastname: Celovska
authors.affiliation: Division of Internal Medicine and Gastroenterology, Catholic University of Sacred Heart, A. Gemelli Medical School, Rome, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Cammarota
authors.affiliation: 2nd Department of Internal Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic.
authors.forename: Katarina
authors.initials: K
authors.lastname: Kusendova
authors.affiliation: 2nd Department of Internal Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic.
authors.forename: Matej
authors.initials: M
authors.lastname: Bendzala
authors.affiliation: Department of Gastroenterology, Central University Hospital of Asturias (HUCA), Oviedo, Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Rodrigo
authors.affiliation: 2nd Department of Internal Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic.
authors.forename: Andrej
authors.initials: A
authors.lastname: Dukat
authors.affiliation: Department of Immunology, School of Medicine, Keimyung University, Dalseo-Gu, Daegu, South Korea.
authors.forename: Taeg Kyu
authors.initials: TK
authors.lastname: Kwon
authors.affiliation: Department of Physiology, Charles University in Prague, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.|Biomedical Centre, Charles University in Prague, Faculty of Medicine in Pilsen, Pilsen, Czech Republic.
authors.forename: Magdalena Chottova
authors.initials: MC
authors.lastname: Dvorakova
authors.affiliation: 2nd Department of Internal Medicine, Comenius University and University Hospital, Bratislava, Slovak Republic.
authors.forename: Ludovit
authors.initials: L
authors.lastname: Gaspar
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood*; D015444:Exercise; D005215:Fasting / Q000097:blood*; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D019518:Postprandial Period; D057185:Sedentary Behavior; D014280:Triglycerides / Q000097:blood*; D055815:Young Adult
chemical_list: D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol