title: [PRIMARY BILIARY LIVER CIRRHOSIS: MODERN CONCEPTS].
abstract: Modern data on primary biliary liver cirrhosis are presented including the definition, prevalence, possible etiological factors, and detailed description of pathogenesis (autoimmune mechanisms, intrahepatic cholestasis, hereditary predisposition, environmental factors) and clinical picture. Also considered are complications and concomitant diseases, methods of laboratory, instrumental and morphological diagnostics, approaches to medicamental treatment and its effectiveness, indications for liver transplantation.
authors.forename: Ya S
authors.initials: YS
authors.lastname: Tsimmerman
mesh_terms: D015551:Autoimmunity; D019468:Disease Management; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D011379:Prognosis; D012307:Risk Factors