title: Comparison of (90)Y activity measurements in nuclear medicine in Germany.
abstract: In 2014, PTB and the company Eckert & Ziegler organized a national comparison exercise to determine the activity of a (90)Y solution. One aim of the comparison was to assess the measurement capability of hospitals and medical practices in Germany. P6-type vials were filled with aliquots of a radioactive (90)Y solution and then sent to 19 participants who were asked to measure the activity in the ampoules as well as in their own standard geometry using syringes. Most of the submitted results have a deviation of less than ±10% from the PTB reference activity when measured in the P6-type vials. The spread is somewhat larger when measured in a syringe geometry. The comparison revealed that some participants have difficulties in applying decay corrections and only a few participants were capable of estimating realistic measurement uncertainties.
authors.affiliation: Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, Germany. Electronic address: Karsten.Kossert@ptb.de.
authors.forename: Karsten
authors.initials: K
authors.lastname: Kossert
authors.affiliation: Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, Germany.
authors.forename: Karen
authors.initials: K
authors.lastname: Bokeloh
authors.affiliation: Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, Germany.
authors.forename: Marion
authors.initials: M
authors.lastname: Ehlers
authors.affiliation: Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, Germany.
authors.forename: Ole
authors.initials: O
authors.lastname: Nähle
authors.affiliation: Eckert & Ziegler Nuclitec GmbH, Gieselweg 1, D-38110 Braunschweig, Germany.
authors.forename: Olaf
authors.initials: O
authors.lastname: Scheibe
authors.affiliation: Eckert & Ziegler Radiopharma GmbH, Robert-Rössle-Straße 10, 13125 Berlin, Germany.
authors.forename: Uwe
authors.initials: U
authors.lastname: Schwarz
authors.affiliation: Eckert & Ziegler Nuclitec GmbH, Gieselweg 1, D-38110 Braunschweig, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Thieme
mesh_terms: D005858:Germany; D007753:Laboratories / Q000592:standards*; D009683:Nuclear Medicine / Q000592:standards*; D011786:Quality Control; D011874:Radiometry / Q000379:methods* / Q000592:standards*; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D015021:Yttrium Radioisotopes / Q000032:analysis* / Q000592:standards*
chemical_list: D015021:Yttrium Radioisotopes
keywords: (90)Y solution; Comparison; Nuclear medicine