title: Early Outcomes With HeartWare HVAD as Bridge to Transplant in Children: A Single Institution Experience.
abstract: The HeartWare HVAD has been used as a bridge to cardiac transplantation in the pediatric population. We describe outcomes following HeartWare HVAD implantation at a single center. A retrospective chart review was performed of all HeartWare HVAD implants performed at our institution between May 2013 and March 2015. Eight children between the ages of 9 and 17 years underwent HVAD implantation as a bridge to transplant (N = 7 cardiomyopathy, N = 1 complex single ventricle). There was one operative death in the complex single ventricle patient. Seven patients (87%) were successfully bridged to transplant. Median time of support was 24.5 days (range, 6-91 days). All transplanted patients are alive and well at a median follow-up of 448 days. Our results demonstrated that mechanical support with HeartWare HVAD is feasible in patients of varying sizes (from older children to adolescents).
authors.affiliation: Division of Pediatric Cardiothoracic Surgery, Children's Medical Center, Dallas, TX, USA.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Ferro
authors.affiliation: Division of Pediatric Cardiothoracic Surgery, Children's Medical Center, Dallas, TX, USA.
authors.forename: Raghav
authors.initials: R
authors.lastname: Murthy
authors.affiliation: Division of Pediatric Cardiothoracic Surgery, Children's Medical Center, Dallas, TX, USA.
authors.forename: Derek
authors.initials: D
authors.lastname: Williams
authors.affiliation: Division of Pediatric Cardiothoracic Surgery, Children's Medical Center, Dallas, TX, USA.
authors.forename: Vinod A
authors.initials: VA
authors.lastname: Sebastian
authors.affiliation: Division of Pediatric Cardiothoracic Surgery, Children's Medical Center, Dallas, TX, USA.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Forbess
authors.affiliation: Division of Pediatric Cardiothoracic Surgery, Children's Medical Center, Dallas, TX, USA.
authors.forename: Kristine J
authors.initials: KJ
authors.lastname: Guleserian
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D005240:Feasibility Studies; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D016027:Heart Transplantation; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D011474:Prosthesis Design; D020127:Recovery of Function; D012189:Retrospective Studies; D013781:Texas; D013997:Time Factors; D016896:Treatment Outcome; D016277:Ventricular Function, Left
keywords: Cardiac transplantation; Heart failure; Pediatric; Ventricular assist device