title: High carbohydrate intake from starchy foods is positively associated with metabolic disorders: a Cohort Study from a Chinese population.
abstract: Starchy foods are the main sources of carbohydrates; however, there is limited information on their metabolic impact. Therefore, we assessed the association between carbohydrates from starchy foods (Carb-S) intakes and the metabolic disorders of metabolic syndrome (MetS) and hyperlipidemia. In this study, 4,154 participants from Northern China were followed up for 4.2 years. Carb-S included rice, refined wheat, tubers, and their products. Multivariable regression models were used to calculate risk ratios (RRs) for MetS and hyperlipidemia from Carb-S, total carbohydrates, and carbohydrates from other food sources (Carb-O). Receiver operating characteristic analysis was used to determine a Carb-S cut-off value. High total carbohydrate intake was associated with increased risks of MetS (RR: 2.24, 95% CI: 1.00-5.03) and hyperlipidemia (RR: 3.05, 95% CI: 1.25-7.45), compared with the first quartile. High Carb-S intake (fourth quartile) was significantly associated with MetS (RR: 1.48, 95% CI: 1.01-2.69) and hyperlipidemia (RR: 1.73, 95% CI: 1.05-3.35). No associations with Carb-O were observed. Visceral adiposity, triglyceride levels, and high-density lipoprotein cholesterol significantly contributed to the metabolic disorders. The Carb-S cut-off value was 220 g. Both high total carbohydrate and Carb-S intakes were associated with hyperlipidemia and MetS; Carb-S appears to contribute more to these disorders.
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China.
authors.forename: Rennan
authors.initials: R
authors.lastname: Feng
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China.
authors.forename: Shanshan
authors.initials: S
authors.lastname: Du
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China.
authors.forename: Sining
authors.initials: S
authors.lastname: Zheng
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China.
authors.forename: Guanqiong
authors.initials: G
authors.lastname: Na
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Nutrition and Food Hygiene, Public Health College, Harbin Medical University, Harbin, China.
authors.forename: Changhao
authors.initials: C
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D044466:Asian People; D015331:Cohort Studies; D004040:Dietary Carbohydrates / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D005502:Food; D038321:Glycemic Index; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology*; D008875:Middle Aged; D016017:Odds Ratio; D012680:Sensitivity and Specificity; D013213:Starch / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D004040:Dietary Carbohydrates; D013213:Starch