title: Chemical Constituents and Activity of Murraya microphylla Essential Oil against Lasioderma serricorne.
abstract: The chemical composition, contact and repellent activities of the essential oil from Murraya microphylla branches and leaves against Lasioderma serricorne adults were determined and six compounds from the essential oil were isolated as well. The essential oil of M microphylla obtained by hydrodistillation was analyzed by gas chromatography-mass spectrometric (GC-MS) analysis; 22 compounds were identified. The main constituents of the essential oil included β-caryophyllene (18.0%), α-pinene (13.8%), spathulenol (9.5%), α-humulene (6.0%), γ-elemene (5.1%) and zingiberene (4.6%), followed by α-cadinol (3.9%) and caryophyllene oxide (3.8%). Six of these compounds were isolated and fully identified as α-pinene, β-caryophyllene, α-humulene, caryophyllene oxide, spathulenol and α-cadinol. L. serricorne adults had different sensitivities to the crude essential oil and isolated compounds. α-Humulene exhibited the strongest contact activity against L. serricorne, showing an LD50 value of 13.1 µg adult(-1). However, spathulenol, the crude essential oil and α-cadinol showed stronger contact activity against L. serricorne than caryophyllene oxide and β-caryophyllene. The essential oil, α-humulene and spathulenol showed comparable repellency against L. serricorne adults at 2 h after exposure, relative to the positive control, DEET. The results demonstrate that the essential oil and isolated compounds exhibited important contact and repellent activities against L. serricorne. Thus, they could become potential natural insecticides or repellents for control of insects in stored products.
authors.forename: Chun-Xue
authors.initials: CX
authors.lastname: You
authors.forename: Shan-Shan
authors.initials: SS
authors.lastname: Guo
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Zhang
authors.forename: Kai
authors.initials: K
authors.lastname: Yang
authors.forename: Cheng-Fang
authors.initials: CF
authors.lastname: Wang
authors.forename: Zhu-Feng
authors.initials: ZF
authors.lastname: Geng
authors.forename: Shu-Shan
authors.initials: SS
authors.lastname: Du
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Deng
authors.forename: Yong-Yan
authors.initials: YY
authors.lastname: Wang
mesh_terms: D000818:Animals; D001517:Coleoptera / Q000187:drug effects*; D007302:Insect Repellents / Q000737:chemistry / Q000494:pharmacology*; D007306:Insecticides / Q000737:chemistry / Q000494:pharmacology*; D032101:Murraya / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D007302:Insect Repellents; D007306:Insecticides; D009822:Oils, Volatile; D010938:Plant Oils