title: Leishmaniosis (Leishmania infantum infection) in dogs.
abstract: The authors present an overview of canine leishmaniosis due to Leishmania infantum. This protozoan is transmitted by sandflies and the disease is frequently characterised by chronic evolution. Cutaneous and visceral clinical signs appear as the infection progresses. Lymph node enlargement, emaciation and skin lesions are the main signs observed in the classical forms of the disease. Control is difficult since infected dogs remain carriers for years and may relapse at any time. The mass screening of infected animals and their treatment or euthanasia represent the best way to reduce the prevalence of this disease in endemic regions. Further research is needed to improve the efficiency of the vaccines available to protect dogs against infection. This disease is zoonotic; in humans, clinical cases are reported mainly in elderly people, the young and those whose immune systems have been compromised.
authors.forename: M
authors.initials: M
authors.lastname: Gharbi
authors.forename: M
authors.initials: M
authors.lastname: Mhadhbi
authors.forename: A
authors.initials: A
authors.lastname: Rejeb
authors.forename: K
authors.initials: K
authors.lastname: Jaouadi
authors.forename: M
authors.initials: M
authors.lastname: Rouatbi
authors.forename: M A
authors.initials: MA
authors.lastname: Darghouth
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000469:parasitology* / Q000473:pathology; D004285:Dogs; D006801:Humans; D018314:Leishmania infantum; D007898:Leishmaniasis, Visceral / Q000188:drug therapy / Q000453:epidemiology / Q000469:parasitology* / Q000473:pathology; D015047:Zoonoses
chemical_list: D000981:Antiprotozoal Agents