title: HeartWare left ventricular assist device for the treatment of advanced heart failure.
abstract: The importance of mechanical circulatory support in the therapy of advanced heart failure is steadily growing. The rapid developments in the field of mechanical support are characterized by continuous miniaturization and enhanced performance of the assist devices, providing increased pump durability and prolonged patient survival. The HeartWare left ventricular assist device system (HeartWare Inc., Framingham, MA, USA) is a mechanical ventricular assist device with over 8000 implantations worldwide. Compared with other available assist devices it is smaller in size and used in a broad range of patients. The possibility of minimally invasive procedures is one of the major benefits of the device - allowing implants and explants, as well as exchanges of the device with reduced surgical impact. We present here a review of the existing literature on the treatment of advanced heart failure using the HeartWare left ventricular assist device system.
authors.affiliation: Department of Cardiac, Thoracic, Transplantation & Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Jasmin S
authors.initials: JS
authors.lastname: Hanke
authors.affiliation: Department of Cardiac, Thoracic, Transplantation & Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Sebastian V
authors.initials: SV
authors.lastname: Rojas
authors.affiliation: Department of Cardiac, Thoracic, Transplantation & Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Murat
authors.initials: M
authors.lastname: Avsar
authors.affiliation: Department of Cardiac, Thoracic, Transplantation & Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Bara
authors.affiliation: Department of Cardiac, Thoracic, Transplantation & Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Issam
authors.initials: I
authors.lastname: Ismail
authors.affiliation: Department of Cardiac, Thoracic, Transplantation & Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Axel
authors.initials: A
authors.lastname: Haverich
authors.affiliation: Department of Cardiac, Thoracic, Transplantation & Vascular Surgery, Hannover Medical School, Hannover, Germany.
authors.forename: Jan D
authors.initials: JD
authors.lastname: Schmitto
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced; D006333:Heart Failure / Q000601:surgery*; D006353:Heart-Assist Devices / Q000009:adverse effects; D006801:Humans; D019060:Minimally Invasive Surgical Procedures; D019919:Prosthesis Implantation / Q000379:methods; D011788:Quality of Life; D056346:Sternotomy; D020521:Stroke / Q000209:etiology / Q000517:prevention & control; D016019:Survival Analysis; D013927:Thrombosis / Q000209:etiology / Q000517:prevention & control
chemical_list: D000925:Anticoagulants
keywords: cardiac surgery; implantation techniques; left ventricular assist device; minimal-invasive surgery; ventricular assist device