title: Simultaneous determination of cobalt and nickel in vitamin B12 samples using high-resolution continuum source atomic absorption spectrometry.
abstract: Nickel and cobalt were simultaneously assayed in vitamin B12 formulations by using atomic spectrometry. The proposed method is based on a compromise between the proximity of specific Ni and Co spectral lines and the relative abundances of the analytes in the samples. The analytes were found in concentrations ranging from 9.48 to 26.20µg L(-1) (Ni) and from 156.90 to 279.25mg L(-1) (Co) in the commercial samples of vitamin B12. The limits of detection and quantification were 1.21 and 3.64mg L(-1) for Co and 0.39 and 1.19µg L(-1) for Ni. Sample cleanup was not necessary for the determinations, and the interferences were discussed.
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97111-900 Santa Maria, RS, Brasil.
authors.forename: Franciele Rovasi
authors.initials: FR
authors.lastname: Adolfo
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97111-900 Santa Maria, RS, Brasil. Electronic address: pcn1954@gmail.com.
authors.forename: Paulo Cícero
authors.initials: PC
authors.lastname: do Nascimento
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97111-900 Santa Maria, RS, Brasil.
authors.forename: Denise
authors.initials: D
authors.lastname: Bohrer
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97111-900 Santa Maria, RS, Brasil.
authors.forename: Leandro Machado
authors.initials: LM
authors.lastname: de Carvalho
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97111-900 Santa Maria, RS, Brasil.
authors.forename: Carine
authors.initials: C
authors.lastname: Viana
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97111-900 Santa Maria, RS, Brasil.
authors.forename: Ananda
authors.initials: A
authors.lastname: Guarda
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97111-900 Santa Maria, RS, Brasil.
authors.forename: Alexsandro
authors.initials: A
authors.lastname: Nunes Colim
authors.affiliation: Departamento de Química, Universidade Federal de Santa Maria, 97111-900 Santa Maria, RS, Brasil.
authors.forename: Patricia
authors.initials: P
authors.lastname: Mattiazzi
mesh_terms: D002138:Calibration; D003035:Cobalt / Q000032:analysis*; D009532:Nickel / Q000032:analysis*; D013054:Spectrophotometry, Atomic / Q000379:methods*; D013696:Temperature; D013997:Time Factors; D014805:Vitamin B 12 / Q000737:chemistry*
chemical_list: D003035:Cobalt; D009532:Nickel; D014805:Vitamin B 12
keywords: Cobalt; Contamination; Continuum source AAS; Nickel; Simultaneous determination; Vitamin B12