title: Guideline-based management of non-muscle invasive bladder cancer.
abstract: BACKGROUND
  Non-muscle invasive bladder cancer (NMIBC) represents a broad spectrum of disease, the hallmarks of which include disease recurrence and progression. Clinicians have a number of surgical and therapeutic options at their disposal when treating this disease, and the underlying evidence continues to evolve. A number of professional organizations have invested in the development of clinical practice guidelines to guide patient management.
  
  
  METHODS
  We review and summarize four major guidelines, the American Urological Association, the European Association of Urology, the International Consultation on Urological Disease and the National Comprehensive Cancer Network.
  
  
  RESULTS
  Guideline panels differed in their composition, methodological approach and structure of recommendations. Despite this, many recommendations were similar between various panels, although differences are present in panel recommendations related to initial diagnosis and treatment, adjuvant therapy and disease surveillance.
  
  
  CONCLUSIONS
  Guideline recommendations are similar at many decision points that clinicians face when managing NMIBC, although they are far from uniform. While future prospective, well-designed studies will hopefully clarify NMIBC management, urologists ultimately must rely on a combination of evidence-based recommendations, which they should seek to integrate with patients' values and preferences and the individual circumstances to provide the best possible patient care.
authors.affiliation: Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232-2765, USA.
authors.forename: Justin R
authors.initials: JR
authors.lastname: Gregg
authors.affiliation: Department of Urologic Surgery, University of Minnesota, Minneapolis VA Healthcare System, Urology Section, Nashville, TN 37232-2765, USA.
authors.forename: Philipp
authors.initials: P
authors.lastname: Dahm
authors.affiliation: Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232-2765, USA.
authors.forename: Sam S
authors.initials: SS
authors.lastname: Chang
keywords: Bladder cancer; non-muscle invasive; practice guidelines