title: Reproductive Health and Peculiarities of Lipid Peroxidation-Antioxidant Defense System in Men of the Main Ethnic Groups of the Baikal Region.
abstract: Quality of sperm and some parameters of LPO reflecting primary and end stages of oxidation and levels of α-tocopherol and total antioxidant activity were studied in ejaculate samples from 130 men (mean age of 24 years) living in Ulan-Ude, Buryatia Republic. All participants took a part in survey and were examined by an andrologist. The observed peculiarities of LPO and antioxidant defense in Russian men, such as decreased level of substrate supply for the processes of LPO and α-tocopherol, attest to specificity of metabolic processes and development of compensatory reactions of the organism under physiological conditions. LPO processes were more active in Buryat men, which can indicate exposure of cell membranes to toxic oxygen species. However, the observed in these patients significant increase in α-tocopherol concentration reflects adequate functioning of the adaptive and protective mechanisms of the body.
authors.affiliation: Research Center of Family Health and Reproduction, Irkutsk, Russia.
authors.forename: L I
authors.initials: LI
authors.lastname: Kolesnikova
authors.affiliation: Research Center of Family Health and Reproduction, Irkutsk, Russia.
authors.forename: S I
authors.initials: SI
authors.lastname: Kolesnikov
authors.affiliation: Research Center of Family Health and Reproduction, Irkutsk, Russia. nakurashova@yandex.ru.
authors.forename: N A
authors.initials: NA
authors.lastname: Kurashova
authors.affiliation: Institute of Cytology and Genetic, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
authors.forename: L V
authors.initials: LV
authors.lastname: Osadchuk
authors.affiliation: Institute of Cytology and Genetic, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Osadchuk
authors.affiliation: Institute of Cytology and Genetic, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
authors.forename: M I
authors.initials: MI
authors.lastname: Dolgikh
authors.affiliation: Republican Perinatal Center, Uzbekistan, Russia.
authors.forename: B G
authors.initials: BG
authors.lastname: Dashiev
authors.affiliation: Institute of General and Experimental Biology, Siberian Division of the Russian Academy of Sciences, Ulan-Ude, Republic of Buryatia, Russia.
authors.forename: L N
authors.initials: LN
authors.lastname: Shantanova
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D005006:Ethnicity; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology; D008297:Male; D012189:Retrospective Studies; D012426:Russia; D012661:Semen / Q000737:chemistry*; D013091:Spermatogenesis; D055815:Young Adult; D024502:alpha-Tocopherol / Q000032:analysis*
chemical_list: D000975:Antioxidants; D024502:alpha-Tocopherol
keywords: antioxidants; ethnics; lipid peroxidation; men; spermatogenesis