title: α-Arylation/Heteroarylation of Chiral α-Aminomethyltrifluoroborates by Synergistic Iridium Photoredox/Nickel Cross-Coupling Catalysis.
abstract: Direct access to complex, enantiopure benzylamine architectures using a synergistic iridium photoredox/nickel cross-coupling dual catalysis strategy has been developed. New C(sp(3))-C(sp(2)) bonds are forged starting from abundant and inexpensive natural amino acids.
authors.affiliation: Department of Chemistry, University of Pennsylvania, Roy and Diana Vagelos Laboratories, 231 S. 34th St., Philadelphia, PA 19104-6323 (USA).
authors.forename: Mirna
authors.initials: M
authors.lastname: El Khatib
authors.affiliation: Department of Chemistry, University of Pennsylvania, Roy and Diana Vagelos Laboratories, 231 S. 34th St., Philadelphia, PA 19104-6323 (USA).|Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo-FCF/USP (Brazil).
authors.forename: Ricardo Augusto Massarico
authors.initials: RA
authors.lastname: Serafim
authors.affiliation: Department of Chemistry, University of Pennsylvania, Roy and Diana Vagelos Laboratories, 231 S. 34th St., Philadelphia, PA 19104-6323 (USA). gmolandr@sas.upenn.edu.
authors.forename: Gary A
authors.initials: GA
authors.lastname: Molander
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D001881:Borates / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis / Q000528:radiation effects; D007495:Iridium / Q000737:chemistry*; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D010084:Oxidation-Reduction / Q000528:radiation effects; D055668:Photochemical Processes
chemical_list: D000596:Amino Acids; D001881:Borates; D007495:Iridium; D009532:Nickel
keywords: amino acids; cross-coupling; heterocycles; nickel; photochemistry