title: Natural antifungal compounds from the peels of Ipomoea batatas Lam.
abstract: Three antifungal compounds have been isolated for the first time from the peels of Ipomoea batatas Lam. Their structures were established on the basis of 1D and 2D NMR spectra data as well as ESI-MS and IR analysis. Urs-13(18)-ene-3β-yl acetate was found to possess a weak activity against Sporothrix schenckii and Trichophyton metagrophytes fungi with an MIC value of 50 μg/mL each. Stigmasterol and 3-friedelanol were equally active against T. metagrophytes.
authors.affiliation: a Department of Physiscal Science , Landmark University , Omuaran , Nigeria.
authors.forename: Abimbola P
authors.initials: AP
authors.lastname: Oluyori
authors.affiliation: b Medicinal and Process Chemistry Division , Central Drug Research Institute , Lucknow , India.
authors.forename: Arun Kumar
authors.initials: AK
authors.lastname: Shaw
authors.affiliation: b Medicinal and Process Chemistry Division , Central Drug Research Institute , Lucknow , India.
authors.forename: Rastogi
authors.initials: R
authors.lastname: Preeti
authors.affiliation: b Medicinal and Process Chemistry Division , Central Drug Research Institute , Lucknow , India.
authors.forename: Sammajay
authors.initials: S
authors.lastname: Reddy
authors.affiliation: c Department of Chemistry , University of Ilorin , Ilorin , Nigeria.
authors.forename: Olubunmi
authors.initials: O
authors.lastname: Atolani
authors.affiliation: d Department of Industrial Chemistry , University of Ilorin , Ilorin , Nigeria.
authors.forename: Gabriel A
authors.initials: GA
authors.lastname: Olatunji
authors.affiliation: e Department of Crop Protection , University of Ilorin , Ilorin , Nigeria.
authors.forename: Oluwatoyin A
authors.initials: OA
authors.lastname: Fabiyi
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D027723:Ipomoea batatas / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D035281:Plant Tubers / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013175:Sporothrix / Q000187:drug effects; D014249:Trichophyton / Q000187:drug effects; D014315:Triterpenes
chemical_list: C421804:3-friedelanol; D000935:Antifungal Agents; D014315:Triterpenes
keywords: 3-friedelanol; Ipomoea batatas; Peels; Sporothrix schenckii; Trichophyton metagrophytes; stigmasterol