title: Ultrasound-guided versus blind subacromial-subdeltoid bursa injection in adults with shoulder pain: A systematic review and meta-analysis.
abstract: OBJECTIVE
  This systematic review and meta-analysis aimed to assess the effectiveness of ultrasound-guided (USG) versus blind (landmark-guided, LMG) corticosteroid subacromial-subdeltoid bursa injection in adults with shoulder pain.
  
  
  METHODS
  The searches were performed on PubMed, Ovid MEDLINE, Ovid EMBASE, Ovid CochraneCENTRAL, Web of Science, Google Scholar, and Scopus from database inception through March 27, 2015. Studies were included trials comparing USG versus LSG injections for the treatment of adults with subacromial-subdeltoid bursitis. Two reviewers independently performed data extraction and appraisal of the studies. The outcome measures collected were the decreased VAS and SDQ scores, the increased shoulder function scores and shoulder abduction motion range, and the effective rate at 6 weeks after injection.
  
  
  RESULTS
  Seven papers including 445 patients were reviewed; 224 received LMG injections and 221 received USG injections. There was a statistically significant difference in favor of USG for pain score [MD = 1.19, 95% CI (0.39, 1.98), P = 0.003] and SDQ score [MD = 5.01, 95% CI (1.82, 8.19), P = 0.02] at 6 weeks after injection. Also there was a statistically significant difference between the groups, with greater improvement reported of shoulder function scores [SMD = 0.89, 95% CI (0.56, 1.23), P < 0.001] and shoulder abduction motion range [MD 32.69, 95% CI (14.82, 50.56), P < 0.001] in the USG group. More effective rate was also reported with USG group and the difference was statistically significant [risk ratio = 1.6, 95% CI (1.02, 2.50), P = 0.04].
  
  
  CONCLUSIONS
  Ultrasound-guided corticosteroid injections potentially offer a significantly greater clinical improvement over blind SASD bursitis injections in adults with shoulder pain.
authors.affiliation: Department of Rehabilitation Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3, East Qin Chun Road, Hangzhou, Zhe Jiang, 310016, China. Electronic address: wutao1880@163.com.
authors.forename: Tao
authors.initials: T
authors.lastname: Wu
authors.affiliation: Department of Rehabilitation Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3, East Qin Chun Road, Hangzhou, Zhe Jiang, 310016, China.
authors.forename: Hai Xin
authors.initials: HX
authors.lastname: Song
authors.affiliation: Department of Rehabilitation Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3, East Qin Chun Road, Hangzhou, Zhe Jiang, 310016, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Dong
authors.affiliation: Department of Rehabilitation Medicine, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, 3, East Qin Chun Road, Hangzhou, Zhe Jiang, 310016, China.
authors.forename: Jian Hua
authors.initials: JH
authors.lastname: Li
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D002061:Bursa, Synovial / Q000187:drug effects*; D006801:Humans; D007270:Injections, Intra-Articular / Q000379:methods; D020069:Shoulder Pain / Q000188:drug therapy*; D018084:Ultrasonography, Interventional
chemical_list: D000305:Adrenal Cortex Hormones
keywords: Injection; Shoulder; Ultrasound