title: [Severe alveolar haemorrhage related to a silicone embolism syndrome revealed by a chronic penis ulcer: A case report].
abstract: BACKGROUND
  Silicone injections, in particular illegal injections, carried out in an aesthetic purpose, can cause serious complications, like silicone embolism syndrome.
  
  
  METHODS
  We present a 39-year-old man who presented with a severe acute respiratory distress syndrome related to an alveolar hemorrhage associated with a persistent penis ulcer and a genital lymphedema. It was the complications of silicone injections which revealed a severe personality disorder. Diagnosis of silicone embolism syndrome was made, a few years later, thanks to the histopathology study of a persistent penis ulcer with genital lymphedema. The outcome was favorable.
  
  
  CONCLUSIONS
  A serious alveolar hemorrhage in a young patient should raise suspicion of silicone embolism syndrome, especially if there are cutaneous lesions compatible with injections.
authors.affiliation: Département de médecine interne, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Réveillon
authors.affiliation: Service de dermatologie, centre hospitalier du Havre, BP 24, 76083 Le Havre cedex, France.
authors.forename: D
authors.initials: D
authors.lastname: Carré
authors.affiliation: Département de dermatologie, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Plaquevent
authors.affiliation: Département de dermatologie, CHU de Rouen, 1, rue de Germont, 76031 Rouen cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Alsubaiei
authors.affiliation: Service de dermatologie, centre hospitalier du Havre, BP 24, 76083 Le Havre cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Midhat
authors.affiliation: Service de rhumatologie, centre hospitalier du Havre, BP 24, 76083 Le Havre cedex, France.
authors.forename: D
authors.initials: D
authors.lastname: Alcaix
authors.affiliation: Service d'anatomo-pathologie, hôpital Cochin, université Paris V, AP-HP, 27, rue du Faubourg-Saint-Jacques, 75679 Paris cedex 14, France.
authors.forename: F
authors.initials: F
authors.lastname: Plantier
authors.affiliation: Service de dermatologie, hôpital Cochin, université Paris V, AP-HP, 27, rue du Faubourg-Saint-Jacques, 75679 Paris cedex 14, France.
authors.forename: N
authors.initials: N
authors.lastname: Dupin
authors.affiliation: Service de médecine interne, centre national de références pour les vascularites systémiques et la sclérodermie systémique, hôpital Cochin, université Paris V, AP-HP, 27, rue du Faubourg-Saint-Jacques, 75679 Paris cedex 14, France.
authors.forename: B
authors.initials: B
authors.lastname: Terrier
authors.affiliation: Service de médecine interne, centre national de références pour les vascularites systémiques et la sclérodermie systémique, hôpital Cochin, université Paris V, AP-HP, 27, rue du Faubourg-Saint-Jacques, 75679 Paris cedex 14, France.
authors.forename: L
authors.initials: L
authors.lastname: Guillevin
authors.affiliation: Service de dermatologie, centre hospitalier du Havre, BP 24, 76083 Le Havre cedex, France. Electronic address: pierre.bravard@ch-havre.fr.
authors.forename: P
authors.initials: P
authors.lastname: Bravard
mesh_terms: D000328:Adult; D002908:Chronic Disease; D006470:Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D010409:Penile Diseases / Q000139:chemically induced* / Q000175:diagnosis; D011650:Pulmonary Alveoli; D011655:Pulmonary Embolism / Q000139:chemically induced / Q000175:diagnosis; D012128:Respiratory Distress Syndrome / Q000139:chemically induced / Q000175:diagnosis; D012828:Silicones / Q000009:adverse effects*; D014456:Ulcer / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D012828:Silicones
keywords: Alveolar hemorrhage; Genital lymphedema; Hémorragie intra-alvéolaire; Injection de silicone; Lymphœdème génital; Penis ulcer; Silicone embolism syndrome; Silicone injection; Syndrome d’embolie siliconée; Ulcération du pénis