title: Successful treatment of Beauveria bassiana fungal keratitis with topical voriconazole.
abstract: We describe a 66-year-old woman who suffered from fungal keratitis after corneal transplantation. The causative organism was identified as Beauveria bassiana on the basis of morphological characteristics and the sequence of the internal transcribed spacer region of the ribosomal RNA gene. The patient was successfully treated with topical voriconazole (VRCZ) use only. We, hereby, present the first report of a case with B. bassiana fungal keratitis that responded to topical antifungal VRCZ treatment.
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Ogawa
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, Japan. Electronic address: ymatsumoto8@aol.com.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Matsumoto
authors.affiliation: Medical Mycology Research Center, Chiba University, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Yaguchi
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, Japan.
authors.forename: Shigeto
authors.initials: S
authors.lastname: Shimmura
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tsubota
mesh_terms: D060433:Administration, Ophthalmic; D000935:Antifungal Agents / Q000627:therapeutic use*; D052982:Beauveria; D003320:Corneal Ulcer / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy* / Q000382:microbiology; D009883:Ophthalmic Solutions; D065819:Voriconazole / Q000627:therapeutic use*
chemical_list: D000935:Antifungal Agents; D009883:Ophthalmic Solutions; D065819:Voriconazole
keywords: Beauveria bassiana; Descemet stripping automated endothelial keratoplasty; Fungal keratitis; Voriconazole