title: Factors Associated with Severe Leptospirosis, Martinique, 2010-2013.
abstract: To identify factors associated with disease severity, we examined 102 patients with quantitative PCR-confirmed leptospirosis in Martinique during 2010-2013. Associated factors were hypotension, chest auscultation abnormalities, icterus, oligo/anuria, thrombocytopenia, prothrombin time <68%, high levels of leptospiremia, and infection with L. interrogans serovar Icterohaemorrhagiae/Copenhageni.
authors.forename: Patrick
authors.initials: P
authors.lastname: Hochedez
authors.forename: Rafaelle
authors.initials: R
authors.lastname: Theodose
authors.forename: Claude
authors.initials: C
authors.lastname: Olive
authors.forename: Pascale
authors.initials: P
authors.lastname: Bourhy
authors.forename: Guillaume
authors.initials: G
authors.lastname: Hurtrel
authors.forename: Nicolas
authors.initials: N
authors.lastname: Vignier
authors.forename: Hossein
authors.initials: H
authors.lastname: Mehdaoui
authors.forename: Ruddy
authors.initials: R
authors.lastname: Valentino
authors.forename: Roland
authors.initials: R
authors.lastname: Martinez
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Delord
authors.forename: Cécile
authors.initials: C
authors.lastname: Herrmann
authors.forename: Isabelle
authors.initials: I
authors.lastname: Lamaury
authors.forename: Raymond
authors.initials: R
authors.lastname: Césaire
authors.forename: Mathieu
authors.initials: M
authors.lastname: Picardeau
authors.forename: André
authors.initials: A
authors.lastname: Cabié
mesh_terms: D000328:Adult; D000818:Animals; D004196:Disease Outbreaks; D004283:Dog Diseases / Q000453:epidemiology / Q000235:genetics / Q000473:pathology; D004285:Dogs; D005260:Female; D006801:Humans; D007922:Leptospirosis / Q000097:blood / Q000453:epidemiology* / Q000235:genetics; D008297:Male; D008395:Martinique / Q000453:epidemiology; D008875:Middle Aged; D015047:Zoonoses / Q000453:epidemiology
keywords: Leptospira interrogans; Martinique; bacteria; leptospiremia; qPCR; quantitative PCR; serogroup Icterohaemorrhagiae; severe leptospirosis