title: A Preliminary Study of a Transdermal Radiofrequency Device for Body Slimming.
abstract: BACKGROUND
  The use and potential of radiofrequency energy for tissue contracture and body contouring has been established in the literature. Maximum reduction of laxity can be achieved by simultaneously tightening surface tissue and reducing unwanted fat below by the transdermal application of heat to reach and maintain tissue temperature targets within a well-defined range, inducing collagen remodeling in skin as well as apoptosis of fat cells and creating an overall slimming effect. A novel device utilizes transcutaneous monopolar RF for body slimming in this manner, employing a thermistor feedback control mechanism to safely manage energy delivery and tissue temperature.
  
  
  METHODS
  Subjects (n=14) presenting with abdominal laxity were treated up to four times using the transcutaneous monopolar RF device at one or two zones in the abdominal region (at operator's discretion). Non-expert blinded graders rated correction on an arbitrary scale (0=no laxity, 4=maximum laxity) after choosing the order of the before-and-after photo sets. A patient satisfaction survey was also administered.
  
  
  CONCLUSIONS
  The two graders correctly ordered 10 of 14 photo sets in agreement. Average rated improvement was 0.75 and 0.80 for graders 1 and 2, respectively. Patient survey results revealed average perceived tightening of 2.14 points on a 0 to 4 scale (0=lowest tightening result, 4=highest tightening), and 8 of 14 subjects would recommend treatment to others.
  
  
  CONCLUSIONS
  Transdermal monopolar RF is a safe and effective modality for non-invasive body slimming.
authors.forename: Douglas J
authors.initials: DJ
authors.lastname: Key
mesh_terms: D000005:Abdomen; D000273:Adipose Tissue / Q000378:metabolism; D017209:Apoptosis / Q000502:physiology; D003094:Collagen / Q000378:metabolism; D003357:Cosmetic Techniques; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D017060:Patient Satisfaction; D011846:Radio Waves / Q000009:adverse effects; D000078702:Radiofrequency Therapy; D012867:Skin / Q000378:metabolism*; D015595:Skin Aging; D016896:Treatment Outcome
chemical_list: D003094:Collagen