title: Two new simple iridoids from the ant-plant Myrmecodia tuberosa and their antimicrobial effects.
abstract: Six iridoid derivatives (1-6), including two new compounds myrmecodoides A and B (1 and 2), were isolated from the ant-plant Myrmecodia tuberosa. Their structures were determined on the basis of spectroscopic data ((1)H and (13)C NMR, HSQC, HMBC, (1)H-(1)H COSY, NOESY and HR-ESI-MS) and by comparison with the literature values. Among isolates, 3 and 4 exhibit weak antibacterial effect against Staphylococcus aureus subsp. aureus with MIC value of 100.0 μg/mL.
authors.affiliation: a Institute of Ecology and Biological Resources , Vietnam Academy of Science and Technology (VAST) , Hanoi , Vietnam.
authors.forename: Nguyen Phuong
authors.initials: NP
authors.lastname: Hanh
authors.affiliation: b Tay Nguyen Institute for Scientific Research , VAST , Dalat , Vietnam.
authors.forename: Nguyen Huu Toan
authors.initials: NH
authors.lastname: Phan
authors.affiliation: b Tay Nguyen Institute for Scientific Research , VAST , Dalat , Vietnam.
authors.forename: Nguyen Thi Dieu
authors.initials: NT
authors.lastname: Thuan
authors.affiliation: c Institute of Marine Biochemistry , VAST , Hanoi , Vietnam.
authors.forename: Tran Thi Hong
authors.initials: TT
authors.lastname: Hanh
authors.affiliation: c Institute of Marine Biochemistry , VAST , Hanoi , Vietnam.
authors.forename: Le Thi
authors.initials: le T
authors.lastname: Vien
authors.affiliation: c Institute of Marine Biochemistry , VAST , Hanoi , Vietnam.
authors.forename: Nguyen Phuong
authors.initials: NP
authors.lastname: Thao
authors.affiliation: c Institute of Marine Biochemistry , VAST , Hanoi , Vietnam.
authors.forename: Nguyen Van
authors.initials: NV
authors.lastname: Thanh
authors.affiliation: c Institute of Marine Biochemistry , VAST , Hanoi , Vietnam.
authors.forename: Nguyen Xuan
authors.initials: NX
authors.lastname: Cuong
authors.affiliation: d Vietnam National Museum of Nature , VAST , Hanoi , Vietnam.
authors.forename: Nguyen Quoc
authors.initials: NQ
authors.lastname: Binh
authors.affiliation: c Institute of Marine Biochemistry , VAST , Hanoi , Vietnam.
authors.forename: Nguyen Hoai
authors.initials: NH
authors.lastname: Nam
authors.affiliation: c Institute of Marine Biochemistry , VAST , Hanoi , Vietnam.
authors.forename: Phan Van
authors.initials: PV
authors.lastname: Kiem
authors.affiliation: e College of Pharmacy , Chungnam National University , Daejeon , Republic of Korea.
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
authors.affiliation: c Institute of Marine Biochemistry , VAST , Hanoi , Vietnam.
authors.forename: Chau Van
authors.initials: CV
authors.lastname: Minh
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D039823:Iridoids / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D035281:Plant Tubers / Q000737:chemistry; D019666:Rubiaceae / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013211:Staphylococcus aureus / Q000187:drug effects; D014744:Vietnam
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D039823:Iridoids; D010936:Plant Extracts
keywords: Myrmecodia tuberosa; Rubiaceae; ant-plant; antimicrobial activity; iridoid