title: Progress of pharmacogenomic research related to minerals and trace elements.
abstract: Pharmacogenomics explores the variations in both the benefits and the adverse effects of a drug among patients in a target population by analyzing genomic profiles of individual patients. Minerals and trace elements, which can be found in human tissues and maintain normal physiological functions, are also in the focus of pharmacogenomic research. Single-nucleotide polymorphisms (SNPs) affect the metabolism, disposition and efficacy of minerals and trace elements in humans, resulting in changes of body function. This review describes some of the recent progress in pharmacogenomic research related to minerals and trace elements.
authors.forename: Mei-Zi
authors.initials: MZ
authors.lastname: Zeng
authors.forename: Jie
authors.initials: J
authors.lastname: Tang
authors.forename: Zhao-Qian
authors.initials: ZQ
authors.lastname: Liu
authors.forename: Hong-Hao
authors.initials: HH
authors.lastname: Zhou
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000818:Animals; D064420:Drug-Related Side Effects and Adverse Reactions; D023281:Genomics; D006801:Humans; D008903:Minerals / Q000378:metabolism*; D010597:Pharmacogenetics / Q000639:trends*; D020641:Polymorphism, Single Nucleotide; D014131:Trace Elements / Q000378:metabolism*
chemical_list: D008903:Minerals; D014131:Trace Elements