title: Determining the Presence of Superantigens in Coagulase Negative Staphylococci from Humans.
abstract: Superantigens (SAgs) are important virulence factors in S. aureus. Recent studies identified their presence in animal coagulase-negative staphylococci (CNS). The emergence of human-associated SAg+ CNS would mark a prodigious shift in virulence capabilities. We examined CNS isolates from healthy human nares and diseased individuals, and determined that no known SAgs were present.
authors.affiliation: Department of Microbiology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Stach
authors.affiliation: Department of Microbiology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
authors.forename: Bao G
authors.initials: BG
authors.lastname: Vu
authors.affiliation: Department of Microbiology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America.
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Schlievert
mesh_terms: D064368:Healthy Volunteers; D006801:Humans; D013211:Staphylococcus aureus / Q000276:immunology* / Q000302:isolation & purification; D018089:Superantigens / Q000032:analysis* / Q000276:immunology; D037521:Virulence Factors / Q000032:analysis / Q000276:immunology
chemical_list: D018089:Superantigens; D037521:Virulence Factors