title: Crystal structure of 2-[(1R,2R,4aS,8aS)-2-hy-droxy-2,5,5,8a-tetra-methyl-deca-hydro-naphthalen-1-yl]-N-(o-tol-yl)acetamide.
abstract: The title compound, C23H35NO2, is an amide derivative of the lactone (+)-sclareolide, and was synthesized from natural sclareol. In the mol-ecular structure, the two six-membered rings (A and B) of the labdane skeleton are trans-fused, and adopt chair conformations. There is an intra-molecular N-H⋯O hydrogen bond present forming an S(7) ring motif. In the crystal, O-H⋯O hydrogen bonds link the mol-ecules into helical chains propagating along the b-axis direction. The chains are linked via C-H⋯π inter-actions, forming a three-dimensional structure.
authors.affiliation: Lab. for Pesticide Synthesis, Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, Weigang 1, Xuanwu District, Nanjing 210095, People's Republic of China.
authors.forename: Dang-Dang
authors.initials: DD
authors.lastname: Li
authors.affiliation: Xi'an Botanical Garden, Institute of Botany of Shaanxi Province, Xi'an 710061, People's Republic of China.
authors.forename: Xin-Wei
authors.initials: XW
authors.lastname: Shi
authors.affiliation: Xi'an Botanical Garden, Institute of Botany of Shaanxi Province, Xi'an 710061, People's Republic of China.
authors.forename: Qiang-Qiang
authors.initials: QQ
authors.lastname: Lu
authors.affiliation: Lab. for Pesticide Synthesis, Department of Pesticide Science, College of Plant Protection, Nanjing Agricultural University, Weigang 1, Xuanwu District, Nanjing 210095, People's Republic of China.
authors.forename: Sheng-Kun
authors.initials: SK
authors.lastname: Li
keywords: C—H⋯π inter­actions; crystal structure; hydrogen bonding; sclareol; sclareolide