title: Metabolic impact of 100% fruit juice consumption on antioxidant/oxidant status and lipid profiles of adults: An Evidence-Based review.
abstract: One hundred percent fruit juice (FJ) contains bioactive compounds with antioxidant activity. As such, this fruit form has the potential to improve antioxidant status and mediate outcomes influenced by redox status. A systematic review of the literature published between 1995 and 2013 was conducted using PubMed database to evaluate associations between intake of 100% FJ and markers of antioxidant/oxidant status and blood lipid levels in healthy, free-living adults ≥18 years. Data extraction and analysis was conducted according to the Academy of Nutrition and Dietetics Evidence Analysis Process. Limited evidence from ten clinical trials meeting inclusion/exclusion criteria suggests potential improvements in a variety of antioxidant or oxidants biomarkers postconsumption of 100% FJ. Weak evidence from five studies suggests that one or more blood lipid measures may be positively influenced by consumption of 100% FJ. Heterogeneity in study methodology including biomarkers, 100% FJ type, dosage, and intervention duration precludes the ability to make evidence-based recommendations regarding a specific dose-duration-juice effect. Key characteristics in study designs were identified which must either be controlled or statistically adjusted for in future investigations in order to obtain a more accurate understanding of the complex relationship between metabolic outcomes and consumption of 100% FJ in context of a healthy dietary pattern.
authors.affiliation: a University of Alabama , Tuscaloosa , Alabama , USA.
authors.forename: Kristi
authors.initials: K
authors.lastname: Crowe-White
authors.affiliation: b Department of Interdisciplinary Studies, Department of Scientific Nutrition , Rutgers, The State University of New Jersey , Newark , New Jersey , USA.
authors.forename: J Scott
authors.initials: JS
authors.lastname: Parrott
authors.affiliation: c Health Sciences, State University of New York, Empire State College , Saratoga Springs , New York , USA.
authors.forename: Kim S
authors.initials: KS
authors.lastname: Stote
authors.affiliation: d Department of Nutrition and Health Care Management , Appalachian State University , Boone , North Carolina , USA.
authors.forename: Melissa
authors.initials: M
authors.lastname: Gutschall
authors.affiliation: e Department of Health and Nutritional Sciences , South Dakota State University, Health & Nutritional Sciences , Brookings , South Dakota , USA.
authors.forename: Sue
authors.initials: S
authors.lastname: Benson-Davies
authors.affiliation: f South Dakota State University , Department of Health and Nutritional Sciences , South Dakota , USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Droke
authors.affiliation: g School of Nutrition and Food Sciences, Louisiana State University Agricultural Center , Baton Rouge , Louisiana , USA.
authors.forename: Carol E
authors.initials: CE
authors.lastname: O'Neil
authors.affiliation: h Evidence-based Practice, Academy of Nutrition and Dietetics , Chicago , Illinois , USA.
authors.forename: Taylor
authors.initials: T
authors.lastname: Wolfram
authors.affiliation: i Senior Director, Research/Evidence Analysis, Academy of Nutrition and Dietetics , Chicago , Illinois , USA.
authors.forename: Paula
authors.initials: P
authors.lastname: Ziegler
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000009:adverse effects / Q000032:analysis / Q000627:therapeutic use*; D015415:Biomarkers / Q000097:blood; D002986:Clinical Trials as Topic; D000072001:Diet, Healthy; D019317:Evidence-Based Medicine; D005638:Fruit / Q000009:adverse effects / Q000737:chemistry*; D000067030:Fruit and Vegetable Juices / Q000009:adverse effects / Q000032:analysis*; D055951:Functional Food / Q000009:adverse effects / Q000032:analysis*; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D018384:Oxidative Stress; D015203:Reproducibility of Results
chemical_list: D000975:Antioxidants; D015415:Biomarkers
keywords: 100% fruit juice; Evidence Analysis Library; adults; antioxidant status; cholesterol; functional foods; lipids; oxidative stress