title: Height-, extent-, length-, and pupil-based (HELP) algorithm to manage post-phacoemulsification Descemet membrane detachment.
abstract: OBJECTIVE
  To analyze the functional and anatomic outcomes of management of Descemet membrane detachment after phacoemulsification using a protocol based on the detachment's height, extent, and chord length and its relation to the pupil.
  
  
  METHODS
  Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
  
  
  METHODS
  Prospective comparative case series.
  
  
  METHODS
  Eyes with post-phacoemulsification Descemet membrane detachment were managed surgically or medically based on the detachment's height, extent, length (chord), and relation to the pupil (HELP protocol). Central corneal thickness (CCT), chord length, and detachment height were determined by anterior segment optical coherence tomography (AS-OCT) (Visante).
  
  
  RESULTS
  Of 161 eyes, 96 were treated surgically (Group 1) and 65 medically (Group 2). The mean length and mean height of Descemet membrane detachment were 2.4 mm ± 1.4 (SD) and 266 ± 189.8 μm, respectively, in Group 1 and 1.03 ± 0.4 mm and 153.3 ± 60.8 μm, respectively, in Group 2. The complete reattachment rate was 95.8% in Group 1 and 96.9% in Group 2. The corrected distance visual acuity (CDVA) was 20/40 or better in 83.3% of eyes in Group 1 and 92.3% of eyes in Group 2. No eye lost CDVA as a result of a Descemet membrane scar in the central 5.0 mm of the cornea. The AS-OCT allowed visualization of the detachment in all eyes with a CCT of more than 800 μm. There was no difference in the final CDVA between Group 1 and Group 2.
  
  
  CONCLUSIONS
  The AS-OCT-based algorithm was effective for managing post-surgical Descemet membrane detachment in eyes with dense corneal edema. Early surgical intervention for detachments in the central cornea can reduce scarring-induced visual loss.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Dhivya Ashok
authors.initials: DA
authors.lastname: Kumar
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India. Electronic address: dragarwal@vsnl.com.
authors.forename: Amar
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Soundari
authors.initials: S
authors.lastname: Sivanganam
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Radika
authors.initials: R
authors.lastname: Chandrasekar
mesh_terms: D000368:Aged; D000388:Air; D000465:Algorithms; D003316:Corneal Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D003886:Descemet Membrane / Q000473:pathology / Q000601:surgery*; D058450:Endotamponade; D005260:Female; D005466:Fluorocarbons / Q000008:administration & dosage; D006801:Humans; D006982:Hypertonic Solutions / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000009:adverse effects*; D011183:Postoperative Complications; D011446:Prospective Studies; D012422:Rupture, Spontaneous; D013459:Sulfur Hexafluoride / Q000008:administration & dosage; D041623:Tomography, Optical Coherence
chemical_list: D005466:Fluorocarbons; D006982:Hypertonic Solutions; C042852:perflutren; D013459:Sulfur Hexafluoride