title: Quizartinib elicits differential responses that correlate with karyotype and genotype of the leukemic clone.
authors.affiliation: Department of Pathology, Kaiser Permanente Santa Clara, CA, USA.
authors.forename: G E
authors.initials: GE
authors.lastname: Nybakken
authors.affiliation: Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Canaani
authors.affiliation: Department of Pathology, Rowan University, Glassboro, NJ, USA.
authors.forename: D
authors.initials: D
authors.lastname: Roy
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Morrissette
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: C D
authors.initials: CD
authors.lastname: Watt
authors.affiliation: Department of Medicine, Division of Hematology/Oncology, University of California, San Francisco, San Francisco, CA, USA.
authors.forename: N P
authors.initials: NP
authors.lastname: Shah
authors.affiliation: Department of Medicine, Division of Hematology/Oncology, University of California, San Francisco, San Francisco, CA, USA.
authors.forename: C C
authors.initials: CC
authors.lastname: Smith
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: A
authors.initials: A
authors.lastname: Bagg
authors.affiliation: Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA, USA.|Philadelphia Veterans Hospital, Philadelphia, PA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Carroll
authors.affiliation: Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: A E
authors.initials: AE
authors.lastname: Perl
mesh_terms: D052160:Benzothiazoles / Q000494:pharmacology / Q000627:therapeutic use*; D005838:Genotype; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy* / Q000235:genetics; D009154:Mutation; D010671:Phenylurea Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D051941:fms-Like Tyrosine Kinase 3 / Q000235:genetics
chemical_list: D052160:Benzothiazoles; D010671:Phenylurea Compounds; C544967:quizartinib; C497970:FLT3 protein, human; D051941:fms-Like Tyrosine Kinase 3