title: Liver Transplantation for Cholestatic Liver Diseases in Adults.
abstract: Liver transplantation (LT) is an established lifesaving therapy for patients with cholestatic liver diseases, including primary cholestatic diseases, namely primary sclerosing cholangitis and primary biliary cirrhosis, as well as secondary forms of cholestatic liver disease, including those with cholestatic complications of LT needing a retransplant. Patients with cholestatic liver diseases can be transplanted for complications of end-stage liver disease or for disease-specific symptoms before the onset of end-stage liver disease. These patients should be regularly assessed. Patient survival after LT for cholestatic liver diseases is generally better than for other indications.
authors.affiliation: Division of Gastroenterology, University of Pennsylvania, 3400 Spruce Street, 2 Dulles, Philadelphia, PA 19104, USA.
authors.forename: Vandana
authors.initials: V
authors.lastname: Khungar
authors.affiliation: Division of Gastroenterology, University of Pennsylvania, Blockley Hall, 423 Guardian Drive, Room 730, Philadelphia, PA 19104, USA. Electronic address: david.goldberg@uphs.upenn.edu.
authors.forename: David Seth
authors.initials: DS
authors.lastname: Goldberg
mesh_terms: D000328:Adult; D015209:Cholangitis, Sclerosing / Q000601:surgery*; D058625:End Stage Liver Disease / Q000209:etiology / Q000601:surgery; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications / Q000601:surgery*; D016031:Liver Transplantation; D018579:Patient Selection; D012008:Recurrence; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014850:Waiting Lists / Q000401:mortality
keywords: Cholestatic liver disease; Living donor transplantation; MELD exceptions; Waitlist mortality