title: Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate?
abstract: BACKGROUND
  The impact of standard percutaneous nephrolithotomy (PCNL) on short or long-term renal function has been evaluated in many studies. We evaluated the effect of tubeless PCNL on early renal function.
  
  
  METHODS
  A total of 117 patients referring to our university center for PCNL were enrolled in the study if they were matched with the inclusion criteria. Serum creatinine and hemoglobin (Hb) levels were measured before PCNL and 6, 24, 48, and 72 h after the operation. Glomerular filtration rate (GFR) was calculated using Cockroft-Gault formula.
  
  
  RESULTS
  There were 79 (67.5%) men and 38 women (32.5%) with the mean age of 49.94 years ranging from 18 to 80 years in the study group. The mean creatinine level elevated in the first 48 h after PCNL but it started to reduce on the 3(rd) day (mean preoperative creatinine level: 1.32 ± 0.18 mg/dL, mean creatinine level after 48 h: 1.59 ± 0.24 mg/dL, creatinine level after 72 h: 1.42 ± 0.21245 mg/dL) (P < 0.0001). GFR values had the same rise and fall pattern as serum creatinine level (mean preoperative GFR: 74.89 mL/min, mean GFR after 48 h: 64.04 mL/min, GFR after 72 h: 69.54 mL/min, P < 0.0001). PCNL also affected blood Hb level. The mean preoperative Hb level was 15.06 ± 0.87 g/dL and it significantly decreased to 13.09 ± 1.06 g/dL after the operation (P < 0.0005).
  
  
  CONCLUSIONS
  Tubeless PCNL like standard PCNL decreases GFR in the very early postoperative days. It is recommended that factors that might have a negative impact on renal function during first few days after PCNL be avoided.
authors.affiliation: Department of Urology, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Seyed Reza
authors.initials: SR
authors.lastname: Hosseini
authors.affiliation: Department of Urology, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad Ghasem
authors.initials: MG
authors.lastname: Mohseni
authors.affiliation: Department of Urology, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Hamzeh
authors.initials: H
authors.lastname: Roshan
authors.affiliation: Department of Urology, Kidney Transplantation Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Farshid
authors.initials: F
authors.lastname: Alizadeh
keywords: Percutaneous nephrolithotomy; renal function; tubeless