title: Curromycin A as a GRP78 downregulator and a new cyclic dipeptide from Streptomyces sp.
authors.affiliation: Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Hayakawa
authors.affiliation: Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
authors.forename: Minami
authors.initials: M
authors.lastname: Akimoto
authors.affiliation: Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
authors.forename: Akari
authors.initials: A
authors.lastname: Ishikawa
authors.affiliation: Department of Medicinal and Life Science, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
authors.forename: Masumi
authors.initials: M
authors.lastname: Izawa
authors.affiliation: Biological Information Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shin-ya
mesh_terms: D045744:Cell Line, Tumor / Q000187:drug effects; D004151:Dipeptides / Q000096:biosynthesis*; D015536:Down-Regulation; D024881:Drug Resistance, Bacterial / Q000235:genetics; D000091342:Endoplasmic Reticulum Chaperone BiP; D006360:Heat-Shock Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D020128:Inhibitory Concentration 50; D008156:Luciferases; D015394:Molecular Structure; D010080:Oxazoles / Q000494:pharmacology; D053284:Polyunsaturated Alkamides / Q000494:pharmacology*; D011401:Promoter Regions, Genetic; D013302:Streptomyces / Q000235:genetics* / Q000378:metabolism
chemical_list: D004151:Dipeptides; D000091342:Endoplasmic Reticulum Chaperone BiP; C000717247:HSPA5 protein, human; D006360:Heat-Shock Proteins; D010080:Oxazoles; D053284:Polyunsaturated Alkamides; C046081:curromycin A; D008156:Luciferases