title: [The HLA system in the Moroccan population: General review].
abstract: The Moroccan population is an interesting study model of Human Leukocyte Antigen (HLA) polymorphism given its ethnic and genetic diversity. Through an analysis of the literature, this work proposes to establish a balance of knowledge for this population in the field of histocompatibility: HLA diversity, anthropology, transplantation and HLA associations and diseases. This analysis shows that the HLA system has not been fully explored within the Moroccan population. However, the results obtained allowed us to initiate a database reflecting the specific healthy Moroccan population HLA polymorphism to identify immigration flows and relationships with different people of the world and to reveal the association of certain HLA alleles with frequent pathologies. We also propose to analyze the reasons hindering the development of this activity in Morocco and we will try to identify some perspectives.
authors.affiliation: Unité d'immunologie, service de transfusion sanguine et d'hémovigilance, hôpital des Enfants de Rabat, CHU Ibn Sina Rabat, Rabat, Maroc. Electronic address: brickchehrazade@yahoo.fr.
authors.forename: C
authors.initials: C
authors.lastname: Brick
authors.affiliation: Unité d'immunologie, service de transfusion sanguine et d'hémovigilance, hôpital des Enfants de Rabat, CHU Ibn Sina Rabat, Rabat, Maroc.
authors.forename: O
authors.initials: O
authors.lastname: Atouf
authors.affiliation: Unité d'immunologie, service de transfusion sanguine et d'hémovigilance, hôpital des Enfants de Rabat, CHU Ibn Sina Rabat, Rabat, Maroc; UPR d'immunologie, faculté de médecine et de pharmacie, université Mohamed V Souissi, Rabat, Maroc.
authors.forename: M
authors.initials: M
authors.lastname: Essakalli
mesh_terms: D000483:Alleles; D000883:Anthropology; D006680:HLA Antigens / Q000235:genetics; D006239:Haplotypes; D015395:Histocompatibility Antigens Class I; D006801:Humans; D009018:Morocco; D011110:Polymorphism, Genetic
chemical_list: D006680:HLA Antigens; D015395:Histocompatibility Antigens Class I
keywords: Anthropologie; Anthropology; HLA; Luminex™; Moroccan population; Population marocaine; Transplantation