title: Management of Necrotizing Fasciitis and Its Surgical Aspects.
abstract: Necrotizing fasciitis (NF) is a severe and rapidly progressive infectious disease that attacks superficial an as well as deep fascia, subcutaneous fat tissue, and muscle. Although the incidence is of relatively low frequency, the median mortality is high. NF is a great burden to patients and hospitals. The most common cause of NF is trauma injuries, followed by other conditions with comorbidity. A classification for NF was presented concerning microbial cause, depth of infection, and anatomy. But the value of classification is not convincing. Early diagnosis of NF is essential and still to be realized by far. Information from clinic or laboratory might contribute to the purpose. Surgery is used in exploration debridement and tissue reconstruction as the main method with NF. Negative pressure wound therapy has proved to be useful in improving wound bed preparation and healing.
authors.affiliation: Shanghai 9th People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Sun
authors.affiliation: Shanghai 9th People's Hospital, Shanghai Jiao Tong University, Shanghai, China doctortingxie@139.com.
authors.forename: Ting
authors.initials: T
authors.lastname: Xie
mesh_terms: D019115:Fasciitis, Necrotizing / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D006801:Humans; D012307:Risk Factors; D013514:Surgical Procedures, Operative
keywords: debridement; diagnosis; necrotizing fasciitis; negative pressure wound therapy; surgery