title: H1 provides the missing link.
abstract: Adding to the Histone Code at DNA double-strand breaks, Mailand and colleagues now uncover non-degradative ubiquitin marks on linker histone H1 as key signaling intermediates in the DNA damage signal transduction cascade.
authors.affiliation: School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR.|State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong SAR.
authors.forename: Michael S Y
authors.initials: MS
authors.lastname: Huen
authors.affiliation: Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
authors.forename: Junjie
authors.initials: J
authors.lastname: Chen
mesh_terms: D000818:Animals; D053903:DNA Breaks, Double-Stranded; D042421:Histone Code; D006657:Histones / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D034622:RNA Interference; D015398:Signal Transduction; D054875:Ubiquitination
chemical_list: D006657:Histones