title: Eating Locally: Microautophagy and Protein Turnover at the Synapse.
abstract: Mechanisms of local protein quality control in the presynaptic nerve terminal remain largely unknown. In this issue of Neuron, Uytterhoeven et al. (2015) describe a form of synaptic endosomal microautophagy controlling protein rejuvenation, critical for optimal synaptic activity.
authors.affiliation: Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada. Electronic address: peter.mcpherson@mcgill.ca.
authors.forename: Peter S
authors.initials: PS
authors.lastname: McPherson
mesh_terms: D000818:Animals; D001343:Autophagy / Q000235:genetics*; D050883:HSC70 Heat-Shock Proteins / Q000235:genetics*; D013570:Synaptic Membranes / Q000378:metabolism*; D013572:Synaptic Vesicles / Q000378:metabolism*
chemical_list: D050883:HSC70 Heat-Shock Proteins