title: Biocompatible silk step-index optical waveguides.
abstract: Biocompatible optical waveguides were constructed entirely of silk fibroin. A silk film (n=1.54) was encapsulated within a silk hydrogel (n=1.34) to form a robust and biocompatible waveguide. Such waveguides were made using only biologically and environmentally friendly materials without the use of harsh solvents. Light was coupled into the silk waveguides by direct incorporation of a glass optical fiber. These waveguides are extremely flexible, and strong enough to survive handling and manipulation. Cutback measurements showed propagation losses of approximately 2 dB/cm. The silk waveguides were found to be capable of guiding light through biological tissue.
authors.affiliation: Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, USA.
authors.forename: Matthew B
authors.initials: MB
authors.lastname: Applegate
authors.affiliation: Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, USA.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Perotto
authors.affiliation: Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, USA.
authors.forename: David L
authors.initials: DL
authors.lastname: Kaplan
authors.affiliation: Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, USA ; Department of Physics, Tufts University, 4 Colby Street, Medford, MA 02155, USA.
authors.forename: Fiorenzo G
authors.initials: FG
authors.lastname: Omenetto
keywords: (160.1435) Biomaterials; (160.5470) Polymers; (170.3890) Medical optics instrumentation; (230.7370) Waveguides