title: Paediatric necrolytic migratory erythema as a presenting sign of glucagonoma syndrome.
abstract: Glucagonoma syndrome is an extremely rare pancreatic neuroendocrine tumour often associated with necrolytic migratory erythema. While glucagonomas are neoplasms of adulthood, we report the first case in a paediatric patient. We present the case of a 15-year-old girl with a 4-year history of a rash, consistent with necrolytic migratory erythema, found to have a localized glucagonoma. Immediately following resection of the tumour, there was complete resolution of her rash and systemic symptoms. Detection of the cutaneous rash of necrolytic migratory erythema can aid in the early diagnosis of a glucagonoma, as well as the prevention of metastatic disease. To our knowledge, this is the first reported paediatric patient with glucagonoma syndrome.
authors.affiliation: Banner University Medical Center, 1111 E. McDowell Road, Phoenix, AZ, 85006, U.S.A.|Warren Alpert Medical School at Brown University, Rhode Island Hospital, 593 Eddy Street, APC 10, Providence, RI, 02903, U.S.A.
authors.forename: A J
authors.initials: AJ
authors.lastname: Luber
authors.affiliation: Medical Dermatology Specialists, 1331 N. 7th Street, Suite 250, Phoenix, AZ, 85006, U.S.A.
authors.forename: L S
authors.initials: LS
authors.lastname: Ackerman
authors.affiliation: Dermpath Diagnostics, 7485 E. Tanque Verde Road, Tucson, AZ, 85715, U.S.A.
authors.forename: K S
authors.initials: KS
authors.lastname: Culpepper
authors.affiliation: Banner University Medical Center, 1111 E. McDowell Road, Phoenix, AZ, 85006, U.S.A.
authors.forename: C M
authors.initials: CM
authors.lastname: Buschmann
authors.affiliation: Arizona Transplant Associates, 2218 N. 3rd Street, Phoenix, AZ, 85004, U.S.A.
authors.forename: L J
authors.initials: LJ
authors.lastname: Koep