title: Bioengineered FSTL1 Patches Restore Cardiac Function Following Myocardial Infarction.
abstract: Improving the limited ability of the heart to regenerate after infarction is crucial. Researchers now demonstrate that delivery of follistatin-like 1 (FSTL1) into injured hearts via collagen patches stimulates cardiomyocyte proliferation and cardiac functional recovery. These findings highlight the epicardium as a source of novel regenerative factors and biomimetic nanomaterials in cardiac translational medicine.
authors.affiliation: Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia.
authors.forename: Ann-Kristin
authors.initials: AK
authors.lastname: Alteköester
authors.affiliation: Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia. Electronic address: r.harvey@victorchang.edu.au.
authors.forename: Richard P
authors.initials: RP
authors.lastname: Harvey
mesh_terms: D000818:Animals; D005260:Female; D038702:Follistatin-Related Proteins / Q000378:metabolism*; D006801:Humans; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D010496:Pericardium / Q000254:growth & development* / Q000378:metabolism*; D012038:Regeneration
chemical_list: D038702:Follistatin-Related Proteins