title: Chiral bifunctional ferrocenylphosphine catalyzed highly enantioselective [3 + 2] cycloaddition reaction.
abstract: A series of air-stable ferrocenylphosphines LB1-LB8 were designed and prepared in high yields. (R,SFc)-ferrocenylphosphine LB5 was found to efficiently promote the asymmetric [3 + 2] cycloaddition of Morita-Baylis-Hillman carbonates with maleimides to afford the corresponding bicyclic imides with 84-99% ee and 67-99% yield. Interestingly, the configuration of these products was contrary to those reported in the literature.
authors.affiliation: Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of Education, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, PR China. weihuizhong@zjut.edu.cn.
authors.forename: Haiwen
authors.initials: H
authors.lastname: Hu
authors.forename: Shuxian
authors.initials: S
authors.lastname: Yu
authors.forename: Linglong
authors.initials: L
authors.lastname: Zhu
authors.forename: Lingxiu
authors.initials: L
authors.lastname: Zhou
authors.forename: Weihui
authors.initials: W
authors.lastname: Zhong