title: Sir John Cornforth AC CBE FRS: his biosynthetic work.
abstract: Sir John Cornforth's work on the stereochemistry of enzyme reactions involved in the biosynthesis of squalene and cholesterol and in the formation and metabolism of a chiral methyl group in acetyl co-enzyme A, is reviewed.
authors.forename: Rupert
authors.initials: R
authors.lastname: Purchase
authors.forename: James R
authors.initials: JR
authors.lastname: Hanson
mesh_terms: D055162:Biocatalysis; D002621:Chemistry / Q000266:history*; D002784:Cholesterol / Q000096:biosynthesis / Q000378:metabolism; D049673:History, 20th Century; D049674:History, 21st Century
chemical_list: D002784:Cholesterol