title: PROTECTIVE LEVELS OF VARICELLA-ZOSTER ANTIBODY DID NOT EFFECTIVELY PREVENT CHICKENPOX IN AN X-LINKED AGAMMAGLOBULINEMIA PATIENT.
abstract: We describe the case of an eight-year-old boy with X-linked agammaglobulinemia who developed mild varicella despite regular intravenous immunoglobulin (IVIG) therapy. He maintained protective antibody levels against varicella and the previous batches of IVIG that he received had adequate varicella-specific IgG levels. The case illustrates that IVIG may not prevent VZV infection.
authors.affiliation: Departmento de Pediatria, Universidade Federal de São Paulo, São Paulo, SP, Brasil, aimeenobre@yahoo.com.br; belinhagonzalez@hotmail.com; m.isabelmp@uol.com.br; beacarvalho@terra.com.br.
authors.forename: Fernanda Aimée
authors.initials: FA
authors.lastname: Nobre
authors.affiliation: Departmento de Pediatria, Universidade Federal de São Paulo, São Paulo, SP, Brasil, aimeenobre@yahoo.com.br; belinhagonzalez@hotmail.com; m.isabelmp@uol.com.br; beacarvalho@terra.com.br.
authors.forename: Isabela Garrido da Silva
authors.initials: IG
authors.lastname: Gonzalez
authors.affiliation: Departmento de Pediatria, Universidade Federal de São Paulo, São Paulo, SP, Brasil, aimeenobre@yahoo.com.br; belinhagonzalez@hotmail.com; m.isabelmp@uol.com.br; beacarvalho@terra.com.br.
authors.forename: Maria Isabel
authors.initials: MI
authors.lastname: de Moraes-Pinto
authors.affiliation: Departmento de Pediatria, Universidade Federal de São Paulo, São Paulo, SP, Brasil, aimeenobre@yahoo.com.br; belinhagonzalez@hotmail.com; m.isabelmp@uol.com.br; beacarvalho@terra.com.br.
authors.forename: Beatriz Tavares
authors.initials: BT
authors.lastname: Costa-Carvalho
mesh_terms: D000361:Agammaglobulinemia / Q000188:drug therapy / Q000276:immunology*; D000914:Antibodies, Viral / Q000097:blood*; D002644:Chickenpox / Q000175:diagnosis* / Q000276:immunology / Q000517:prevention & control; D002648:Child; D040181:Genetic Diseases, X-Linked / Q000188:drug therapy / Q000276:immunology*; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D007106:Immune Sera / Q000008:administration & dosage*; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D017211:Treatment Failure
chemical_list: D000914:Antibodies, Viral; D007106:Immune Sera; D007074:Immunoglobulin G; C030799:varicella-zoster immune globulin