title: Oral squamous cell carcinoma misdiagnosed as a denture-related traumatic ulcer: A clinical report.
abstract: A 65-year-old woman presented with an ulcerated lesion in the alveolar ridge mucosa, which appeared after new dentures had been inserted. Despite many treatment attempts, the lesion did not recede, even with the interruption of denture wearing. A biopsy was performed, and histopathologic examination revealed an ulcerated, invasive, poorly differentiated oral squamous cell carcinoma. The time from the patient's first contact with the prosthodontist because of the lesion until the appropriate diagnosis was established was approximately 6 months. This clinical report documents a significant delay in the oral squamous cell carcinoma diagnosis and treatment because of a clinical misdiagnosis of a traumatic ulcer resulting from complete dentures. Prosthodontists should be aware of the importance of early diagnosis of oral cancer among elderly prosthesis wearers.
authors.affiliation: Graduate student, Oral Oncology Center, Department of Pathology and Clinical Propedeutics, Araçatuba Dental School, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
authors.forename: Vitor Bonetti
authors.initials: VB
authors.lastname: Valente
authors.affiliation: Doctoral student, Department of Dental Materials and Prosthodonthics, Araçatuba Dental School, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
authors.forename: Aline Satie
authors.initials: AS
authors.lastname: Takamiya
authors.affiliation: Doctoral student, Oral Oncology Center, Department of Pathology and Clinical Propedeutics, Araçatuba Dental School, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
authors.forename: Lígia Lavezo
authors.initials: LL
authors.lastname: Ferreira
authors.affiliation: Assistant Professor, Department of Pathology and Clinical Propedeutics, Araçatuba Dental School, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
authors.forename: Renata Callestini
authors.initials: RC
authors.lastname: Felipini
authors.affiliation: Associate Professor, Oral Oncology Center, Department of Pathology and Clinical Propedeutics, Araçatuba Dental School, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
authors.forename: Éder Ricardo
authors.initials: ÉR
authors.lastname: Biasoli
authors.affiliation: Associate Professor, Oral Oncology Center, Department of Pathology and Clinical Propedeutics, Araçatuba Dental School, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil.
authors.forename: Glauco Issamu
authors.initials: GI
authors.lastname: Miyahara
authors.affiliation: Assistant Professor, Oral Oncology Center, Department of Pathology and Clinical Propedeutics, Araçatuba Dental School, São Paulo State University (UNESP), Araçatuba, São Paulo, Brazil. Electronic address: danielbernabe@foa.unesp.br.
authors.forename: Daniel Galera
authors.initials: DG
authors.lastname: Bernabé
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D003824:Denture, Complete / Q000009:adverse effects; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009062:Mouth Neoplasms / Q000175:diagnosis*; D013282:Stomatitis, Denture; D014456:Ulcer / Q000150:complications / Q000175:diagnosis*