title: Comparison the results of two different vestibular system surgery in patients with persistent Meniere's disease.
abstract: BACKGROUND
  Incidence rates of Meniere's disease vary considerably from 157/100,000 in the United Kingdom to 15/100,000 in the United States. Furthermore, in Iran prevalence of Meniere's disease is high, whereas we have not a reliable statistical study on it. A wide range of treatments are used for the treatment of the condition with no consensus on the most effective intervention. The aim of the present study, which involved 37 patients treated because of severe vertigo due to persistent Meniere's disease from 1996 to 2011, was to compare the effectiveness of two surgical methods cochleosacculotomy and endolymphatic sac decompression on vertigo and tinnitus.
  
  
  METHODS
  In a cross-sectional study, we compared two surgical approaches in patients with Meniere's disease who did not respond to usual medical treatment. Twenty-three patients underwent cochleosacculotomy surgery and 14 patients endolymphatic sac decompression surgery. We compared all the patients for resolving of vertigo, tinnitus.
  
  
  RESULTS
  After surgery, in patients of both group vertigo was improved significantly (P < 0.0001), tinnitus was improved, but it was not significant (P > 0.05) and hearing level was worse than before (especially in patients who had undergone cochleosacculotomy) (P < 0.0001).
  
  
  CONCLUSIONS
  Based on the data of the current study, cochleosacculotomy and endolymphatic sac decompression improved vertigo in patients with persistent Meniere's disease.
authors.affiliation: Department of Otolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Saeed
authors.initials: S
authors.lastname: Soheilipour
authors.affiliation: Department of Otolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Seyed Hamidreza
authors.initials: SH
authors.lastname: Abtahi
authors.affiliation: Department of Otolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Soltani
authors.affiliation: Research Center, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Hesam-Al-Din
authors.initials: HA
authors.lastname: Khodadadi
keywords: Cochleosacculotomy; Meniere's disease; endolymphatic sac decompression