title: Telmisartan induced urticarial vasculitis.
abstract: A 53-year-old man developed urticarial vasculitis following ingestion of telmisartan and hydrochlorothiazide combination for hypertension. Treatment with prednisolone and cetirizine was curative, but his lesions recurred when he continued telmisartan and hydrochlorothiazide against medical advice. Re-challenge with the same doses of telmisartan precipitated similar lesions with telmisartan and not with hydrochlorothiazide. This uncommon cutaneous adverse reaction of angiotensin II receptor blockers has implication for the clinicians as more such cases may become apparent with their wider use than in premarketing studies.
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Dr. R. P. Government Medical College, Kangra (Tanda), Himachal Pradesh, India.
authors.forename: Vikram K
authors.initials: VK
authors.lastname: Mahajan
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Dr. R. P. Government Medical College, Kangra (Tanda), Himachal Pradesh, India.
authors.forename: Ravinder
authors.initials: R
authors.lastname: Singh
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Dr. R. P. Government Medical College, Kangra (Tanda), Himachal Pradesh, India.
authors.forename: Mrinal
authors.initials: M
authors.lastname: Gupta
authors.affiliation: Department of Pathology, Dr. R. P. Government Medical College, Kangra (Tanda), Himachal Pradesh, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Raina
mesh_terms: D047228:Angiotensin II Type 1 Receptor Blockers / Q000008:administration & dosage / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001562:Benzimidazoles / Q000008:administration & dosage / Q000009:adverse effects*; D001565:Benzoates / Q000008:administration & dosage / Q000009:adverse effects*; D004338:Drug Combinations; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D000077333:Telmisartan; D014581:Urticaria / Q000139:chemically induced*; D014657:Vasculitis / Q000139:chemically induced*
chemical_list: D047228:Angiotensin II Type 1 Receptor Blockers; D000959:Antihypertensive Agents; D001562:Benzimidazoles; D001565:Benzoates; D004338:Drug Combinations; D006852:Hydrochlorothiazide; D000077333:Telmisartan
keywords: Angiotensin-converting-enzyme inhibitors; angiotensin II receptor blocker; ecchymosis; urticaria