title: Medical Therapy for Inflammatory Bowel Disease.
abstract: Surgeons often care for patients with inflammatory bowel disease (IBD) who are receiving therapies that can include 5-ASA compounds, steroids, immunomodulators, and biologics. The goal of these agents is to suppress intestinal inflammation, ultimately improving the quality of life in patients afflicted with IBD. Traditionally, an acceptable therapeutic endpoint was the resolution of symptoms, defined as clinical remission. However, as a result of recent advances in therapy, clinicians can now strive to achieve more stringent endpoints, such as endoscopic or histologic remission. Many different classes of agents can be used, individually or in combination, to achieve mucosal healing.
authors.affiliation: Division of Gastroenterology & Hepatology, Medical University of South Carolina, 114 Doughty Street, Suite 249, MSC 702, Charleston, SC 29425-2900, USA.
authors.forename: Panayiotis
authors.initials: P
authors.lastname: Grevenitis
authors.affiliation: Division of Gastroenterology & Hepatology, Medical University of South Carolina, 114 Doughty Street, Suite 249, MSC 702, Charleston, SC 29425-2900, USA.
authors.forename: Arul
authors.initials: A
authors.lastname: Thomas
authors.affiliation: Division of Gastroenterology & Hepatology, Medical University of South Carolina, 114 Doughty Street, Suite 249, MSC 702, Charleston, SC 29425-2900, USA. Electronic address: lodhia@musc.edu.
authors.forename: Nilesh
authors.initials: N
authors.lastname: Lodhia
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001688:Biological Products / Q000627:therapeutic use*; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D001688:Biological Products; D007155:Immunologic Factors
keywords: Crohn's disease; Fistula; Fulminant colitis; Inflammatory bowel disease; Perioperative management; Ulcerative colitis