title: Switchable asymmetric bio-epoxidation of α,β-unsaturated ketones.
abstract: Efficient asymmetric bio-epoxidation of electron-deficient α,β-unsaturated ketones was realized via a tandem reduction-epoxidation-dehydrogenation cascade, which proceeds in a switchable manner to afford either chiral epoxy ketones or allylic epoxy alcohols with up to >99% yield and >99%ee.
authors.affiliation: Key Laboratory of Environmental and Applied Microbiology of CAS & Environmental Microbiology Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China. wuzhl@cib.ac.cn.
authors.forename: Yu-Chang
authors.initials: YC
authors.lastname: Liu
authors.affiliation: Key Laboratory of Environmental and Applied Microbiology of CAS & Environmental Microbiology Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China. wuzhl@cib.ac.cn.
authors.forename: Zhong-Liu
authors.initials: ZL
authors.lastname: Wu
mesh_terms: D004852:Epoxy Compounds / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*
chemical_list: D004852:Epoxy Compounds; D007659:Ketones