title: DNA Repair.
abstract: DNA is constantly damaged by various endogenous and exogenous events. Repair systems constantly scan the genome for DNA lesions and replace damaged and mismatched bases, which finally enables the complex DNA double strand to store genetic information. This year's Nobel Prize in Chemistry was awarded to pioneers in this field, T. Lindahl, P. Modrich, and A. Sancar.
authors.affiliation: Center for Integrated Protein Science, CiPSM, Department für Chemie, Ludwig-Maximilians Universität München, Butenandtstrasse 5-13, 81377 München (Germany) http://www.carellgroup.de. thomas.carell@lmu.de.
authors.forename: Thomas
authors.initials: T
authors.lastname: Carell
mesh_terms: D003461:Crystallography; D004247:DNA / Q000737:chemistry; D004260:DNA Repair; D009690:Nucleic Acid Conformation; D018384:Oxidative Stress
chemical_list: D004247:DNA
keywords: DNA damage; DNA repair; biochemistry; genetic information; medicinal chemistry