title: [Systematic review of the efectiveness of community-based interventions to decrease neonatal mortality].
abstract: We evaluated the efficacy/effectiveness of community-based interventions to decrease neonatal mortality. A systematic review of randomized controlled trials, cluster randomized trials and cohort studies of interventions on pregnant women, neonates (up to 28 days after birth) or both was made. Thirty four studies were evaluated (n=844,989): 20 in pregnant women (n=406,172), 6 in neonates (n=24,994), and 8 in both (n=413,823). Risk of bias was generally low. There was heterogeneity among interventions. Interventions such as maternal health education and maternal and neonatal home care were associated to a decrease in neonatal mortality in half of the 6 studies of each group. Supplementation with multiple micronutrients, kangaroo mother care, and maternal supplementation with vitamin A did not decrease neonatal mortality. A few heterogeneous community-based interventions demonstrated a decrease in neonatal mortality.
authors.affiliation: Escuelas de Posgrado y Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú
authors.forename: Adrián V
authors.initials: AV
authors.lastname: Hernández
authors.affiliation: Department of Medicine, Case Western Reserve University, Ohio, EE. UU.
authors.forename: Vinay
authors.initials: V
authors.lastname: Pasupuleti
authors.affiliation: Facultad de Medicina, Universidad Particular San Martin de Porres, Lima, Perú
authors.forename: Vicente
authors.initials: V
authors.lastname: Benites-Zapata
authors.affiliation: PARSALUD II, Lima, Perú
authors.forename: Enrique
authors.initials: E
authors.lastname: Velásquez-Hurtado
authors.affiliation: PARSALUD II, Lima, Perú
authors.forename: Jessica
authors.initials: J
authors.lastname: Loyola-Romaní
authors.affiliation: PARSALUD II, Lima, Perú
authors.forename: Yuleika
authors.initials: Y
authors.lastname: Rodríguez-Calviño
authors.affiliation: PARSALUD II, Lima, Perú
authors.forename: Henry
authors.initials: H
authors.lastname: Cabrera-Arredondo
authors.affiliation: PARSALUD II, Lima, Perú
authors.forename: Marco
authors.initials: M
authors.lastname: Gonzales-Noriega
authors.affiliation: PARSALUD II, Lima, Perú
authors.forename: Walter
authors.initials: W
authors.lastname: Vigo-Valdez
mesh_terms: D015331:Cohort Studies; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D011247:Pregnancy; D011295:Prenatal Care