title: Anti-Staphylococcus aureus activity of methanol extracts of 12 plants used in Cameroonian folk medicine.
abstract: BACKGROUND
  The emergence of bacterial infections including those associated with Staphylococcus aureus causes a benefit of interest to medicinal plants as an effective means of control. The present study was designed to investigate the activities of 12 selected Cameroonian medicinal plants against S. aureus isolates.
  
  
  METHODS
  The plant extracts were prepared by maceration in methanol at laboratory temperature. Qualitative phytochemical analysis was performed by chemical reaction methods. The broth microdilution method was used to evaluate the activities of plant extracts against 11 S. aureus clinical isolates.
  
  
  RESULTS
  Dacryodes edulis was found to have significant antibacterial activity on all the S. aureus isolates (MIC = 64-256 µg/ml). Occimum gratissimum revealed significant inhibitory activity on 9 of the 11 isolates while Commelina erecta and Spilanthes filicaulis revealed similar results on 6 of the 11 clinical isolates.
  
  
  CONCLUSIONS
  The present findings showed that D. eduli, O. gratissimum, C. erecta and S. filicaulis possess interesting inhibitory properties against S. aureus species. These plants could therefore be good candidates to overcome infectious diseases associated with these microorganisms.
authors.affiliation: Laboratory of Microbiology and Antimicrobial Substances, Faculty of Science, P.O. Box 67, Dschang, Cameroon. safole@yahoo.fr.
authors.forename: Leonard
authors.initials: L
authors.lastname: Sama Fonkeng
authors.affiliation: Institute of Fisheries and Aquatic Sciences, University of Douala, P.O. Box 7236, Douala, Cameroon. moraysi@yahoo.fr.
authors.forename: Raymond Simplice
authors.initials: RS
authors.lastname: Mouokeu
authors.affiliation: Laboratory of Microbiology and Antimicrobial Substances, Faculty of Science, P.O. Box 67, Dschang, Cameroon. tumechrist@yahoo.com.
authors.forename: Christopher
authors.initials: C
authors.lastname: Tume
authors.affiliation: Laboratory of Microbiology and Antimicrobial Substances, Faculty of Science, P.O. Box 67, Dschang, Cameroon. njatguysedars@yahoo.fr.
authors.forename: Guy Sedar Singor
authors.initials: GS
authors.lastname: Njateng
authors.affiliation: Laboratory of Microbiology and Antimicrobial Substances, Faculty of Science, P.O. Box 67, Dschang, Cameroon. kmodette@yahoo.fr.
authors.forename: Monique Odette
authors.initials: MO
authors.lastname: Kamcthueng
authors.affiliation: Laboratory of Microbiology and Antimicrobial Substances, Faculty of Science, P.O. Box 67, Dschang, Cameroon. jinettus@yahoo.fr.
authors.forename: Nfozon Jinette
authors.initials: NJ
authors.lastname: Ndonkou
authors.affiliation: Laboratory of Microbiology and Antimicrobial Substances, Faculty of Science, P.O. Box 67, Dschang, Cameroon. jrkuiate@yahoo.com.
authors.forename: Jules-Roger
authors.initials: JR
authors.lastname: Kuiate
mesh_terms: D002163:Cameroon; D016488:Medicine, African Traditional; D000432:Methanol / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000145:classification*; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D010936:Plant Extracts; D000432:Methanol