title: [Mineralocorticoid receptor antagonists in the treatment of patients with chronic heart failure. Positions in 2015].
abstract: Mineralocorticoid receptor antagonists (MCRA) are part of standard medical therapy for heart failure (HF). The clinical efficacy of MCRA in patients with systolic HF has been proven by randomized clinical trials. The efficacy of this drug group in patients with chronic HF with preserved left ventricular systolic function and the advent and practical introductions of safer new-generation MCRA remain to be answered.
authors.affiliation: Department of Myocardial Diseases and Heart Failure, A.L. Myasnikov Institute of Clinical Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health of Russia, Moscow.
authors.forename: Yu F
authors.initials: YF
authors.lastname: Osmolovskaya
authors.affiliation: Department of Myocardial Diseases and Heart Failure, A.L. Myasnikov Institute of Clinical Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health of Russia, Moscow.
authors.forename: I V
authors.initials: IV
authors.lastname: Zhirov
authors.affiliation: Department of Myocardial Diseases and Heart Failure, A.L. Myasnikov Institute of Clinical Cardiology, Russian Cardiology Research-and-Production Complex, Ministry of Health of Russia, Moscow.
authors.forename: S N
authors.initials: SN
authors.lastname: Tereshchenko
mesh_terms: D000077545:Eplerenone; D054143:Heart Failure, Systolic / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D000451:Mineralocorticoid Receptor Antagonists / Q000494:pharmacology; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D013148:Spironolactone / Q000031:analogs & derivatives* / Q000494:pharmacology*; D016896:Treatment Outcome; D016277:Ventricular Function, Left / Q000187:drug effects*
chemical_list: D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone; D000077545:Eplerenone