title: Reactivation of Goodpasture Disease During the Third Trimester of Pregnancy: A Case Report.
abstract: BACKGROUND
  Active Goodpasture disease (GD) in pregnancy is extremely rare and can result in significant maternal and fetal morbidity. Relapse of GD in a subsequent pregnancy has not been reported. Factors associated with a relapse of GD are unknown.
  
  
  METHODS
  A woman in her second pregnancy presented with clinical findings of preeclampsia and biopsy evidence of GD in the third trimester. Her first puerperium was also complicated by GD, requiring temporary hemodialysis. After her second pregnancy she developed terminal renal failure.
  
  
  CONCLUSIONS
  Active GD is extremely rare in pregnancy and has never been reported in 2 successive pregnancies in the same patient. Pregnancy and preeclampsia may be risk factors for a GD relapse, and women with GD contemplating pregnancy should be counseled accordingly.
authors.forename: Sarah
authors.initials: S
authors.lastname: Friend
authors.forename: Stephen James
authors.initials: SJ
authors.lastname: Carlan
authors.forename: Jack
authors.initials: J
authors.lastname: Wilson
authors.forename: Mario
authors.initials: M
authors.lastname: Madruga
mesh_terms: D019867:Anti-Glomerular Basement Membrane Disease; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia; D011247:Pregnancy; D011248:Pregnancy Complications; D011263:Pregnancy Trimester, Third; D012008:Recurrence; D055815:Young Adult