title: ERAIZDA: a model for holistic annotation of animal infectious and zoonotic diseases.
abstract: There is an urgent need for a unified resource that integrates trans-disciplinary annotations of emerging and reemerging animal infectious and zoonotic diseases. Such data integration will provide wonderful opportunity for epidemiologists, researchers and health policy makers to make data-driven decisions designed to improve animal health. Integrating emerging and reemerging animal infectious and zoonotic disease data from a large variety of sources into a unified open-access resource provides more plausible arguments to achieve better understanding of infectious and zoonotic diseases. We have developed a model for interlinking annotations of these diseases. These diseases are of particular interest because of the threats they pose to animal health, human health and global health security. We demonstrated the application of this model using brucellosis, an infectious and zoonotic disease. Preliminary annotations were deposited into VetBioBase database (http://vetbiobase.igbb.msstate.edu). This database is associated with user-friendly tools to facilitate searching, retrieving and downloading of disease-related information. Database URL: http://vetbiobase.igbb.msstate.edu.
authors.affiliation: Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762 USA, Institute for Genomics, Biocomputing & Biotechnology (IGBB), Mississippi State University, Mississippi State, MS 39762 USA, tbuza@igbb.msstate.edu.
authors.forename: Teresia M
authors.initials: TM
authors.lastname: Buza
authors.affiliation: Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762 USA and.
authors.forename: Sherman W
authors.initials: SW
authors.lastname: Jack
authors.affiliation: National Livestock Resources Research Institute (NaLIRRI), Tororo, Uganda.
authors.forename: Halid
authors.initials: H
authors.lastname: Kirunda
authors.affiliation: Department of Pathobiology and Population Medicine, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762 USA and.
authors.forename: Margaret L
authors.initials: ML
authors.lastname: Khaitsa
authors.affiliation: Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762 USA.
authors.forename: Mark L
authors.initials: ML
authors.lastname: Lawrence
authors.affiliation: Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762 USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Pruett
authors.affiliation: Institute for Genomics, Biocomputing & Biotechnology (IGBB), Mississippi State University, Mississippi State, MS 39762 USA.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Peterson
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002006:Brucellosis / Q000235:genetics; D003141:Communicable Diseases / Q000235:genetics*; D019992:Databases as Topic; D058977:Molecular Sequence Annotation; D057386:Search Engine; D012984:Software; D015047:Zoonoses / Q000235:genetics*
chemical_list: D015415:Biomarkers