title: Applications of high dimensionality experiments to biomolecular NMR.
abstract: High dimensionality NMR experiments facilitate resonance assignment and precise determination of spectral parameters such as coupling constants. Sparse non-uniform sampling enables acquisition of experiments of high dimensionality with high resolution in acceptable time. In this review we present and compare some significant applications of NMR experiments of dimensionality higher than three in the field of biomolecular studies in solution.
authors.affiliation: Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Żwirki i Wigury 101, 02-089 Warsaw, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Nowakowski
authors.affiliation: Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Żwirki i Wigury 101, 02-089 Warsaw, Poland.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Saxena
authors.affiliation: Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Żwirki i Wigury 101, 02-089 Warsaw, Poland.
authors.forename: Jan
authors.initials: J
authors.lastname: Stanek
authors.affiliation: Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Żwirki i Wigury 101, 02-089 Warsaw, Poland.
authors.forename: Szymon
authors.initials: S
authors.lastname: Żerko
authors.affiliation: Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Żwirki i Wigury 101, 02-089 Warsaw, Poland. Electronic address: kozmin@chem.uw.edu.pl.
authors.forename: Wiktor
authors.initials: W
authors.lastname: Koźmiński
mesh_terms: D006801:Humans; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011506:Proteins / Q000737:chemistry; D012313:RNA / Q000737:chemistry; D012996:Solutions
chemical_list: D011506:Proteins; D012996:Solutions; D012313:RNA
keywords: NMR spectroscopy; Non-uniform sampling; Proteins; RNA; Sparse sampling