title: Colon Adenocarcinoma Associated with Synchronous Extramural Gastrointestinal Stromal Tumor (GIST) of the Ileum.
abstract: BACKGROUND
  GISTs are mesenchymal tumors representing approximately 1% of all gastrointestinal neoplasia. Their concurrence with colorectal cancers is rare.
  
  
  METHODS
  We present a case of coexistence of colon adenocarcinoma and GIST of the ileum in a 68-year-old white woman.
  
  
  CONCLUSIONS
  The coexistence of mesenchymal and epithelial neoplasia is very challenging; further research is needed to clarify the role of oncogenic mutations and signalling pathways in carcinogenesis of neoplasia of various histiogenic origins.
authors.affiliation: Department of Surgical Oncology, Theageneio Anticancer Hospital, Thessaloniki, Greece.
authors.forename: Paschalis
authors.initials: P
authors.lastname: Gavriilidis
authors.affiliation: Department of Pathology, Theageneio Anticancer Hospital, Thessaloniki, Greece.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Nikolaidou
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000601:surgery; D000368:Aged; D003082:Colectomy / Q000379:methods; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007078:Ileal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D007082:Ileum / Q000473:pathology / Q000601:surgery; D009378:Neoplasms, Multiple Primary