title: [Clinical effect on the treatment of the low-middle frequency sudden hearing loss with postaurical injection of methylprednisolone].
abstract: OBJECTIVE
  To evaluate the clinical efficacy on the treatment of the low-middle frequency sudden hearing loss with postaurical injection of methylprednisolone.
  
  
  METHODS
  The 80 cases of the low-middle frequency sudden hearing loss were randomly divided into postaurical injection and oral hormone groups. The postaurical injection group (42 cases) received the postaurical injection of methylprednisolone, 40 mg/2 d, combined with the treatment of Ginkgo dipyidamolum and Alprostadil for 14 d; The oral hormone group (38 cases) received the oral prednisone, 1 mg/kg/d, administrated once on the morning for 3 d, if effective, prolonging for another 2 d, as mentioned above for Ginkgo dipyidamolum and Alprostadil.
  
  
  RESULTS
  The total effective rate was 88.10% in postaurical injection group and 86. 4o%in oral hormone group. There was no significant difference between the twbogroups( P> 0. 5).
  
  
  CONCLUSIONS
  Postaurical injection of methylprednisolone for the low-middle frequency sudden hearing loss is effective, safe and simple, which may be an alternative for systemic administration of gulcocorticoid.
authors.forename: Sien
authors.initials: S
authors.lastname: Wu
authors.forename: Qingming
authors.initials: Q
authors.lastname: Li
authors.forename: Suhong
authors.initials: S
authors.lastname: Huang
mesh_terms: D000527:Alprostadil / Q000627:therapeutic use; D001688:Biological Products / Q000627:therapeutic use; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000627:therapeutic use; D006319:Hearing Loss, Sensorineural; D003639:Hearing Loss, Sudden / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D001688:Biological Products; D005938:Glucocorticoids; D000527:Alprostadil; D011241:Prednisone; D008775:Methylprednisolone