title: A New Flavanone from the Leaves of Chromolaena odorata.
abstract: Chromolaena odorata (Syn: Eupatorium odoratum) is a perennial plant belonging to the Asteraceae family. Extracts of C. odorata have shown strong anti-oxidant and moderate anti-adipogenenesis activities. Detailed phytochemical investigation of C. odorata led to the isolation of 21 secondary metabolites, which include a new flavanone (3), and a chalcone, 3,2'-dihydroxy-4,4',5',6'-tetramethoxychalcone (2), reported for the first time from a natural source, besides three known compounds 1, 4 and 5, all of which are reported for the first time from C. odorata. Some of these compounds exhibited potent anti-oxidant and anti-adipogenesis activities and these may be partly responsible for the activity of the extract.
authors.forename: Lakshmareddy
authors.initials: L
authors.lastname: Emani
authors.forename: Suryachandrarao
authors.initials: S
authors.lastname: Ravada
authors.forename: Bharani
authors.initials: B
authors.lastname: Meka
authors.forename: Machiraju
authors.initials: M
authors.lastname: Garaga
authors.forename: Trimurtulu
authors.initials: T
authors.lastname: Golakoti
mesh_terms: D036604:Chromolaena / Q000737:chemistry*; D044950:Flavanones / Q000737:chemistry*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry*
chemical_list: D044950:Flavanones