title: A versatile approach to flavones via a one-pot Pd(II)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones.
abstract: A variety of flavones were expediently synthesized from readily accessible chromanones via a one-pot sequence involving Pd(II)-catalyzed dehydrogenation and oxidative boron-Heck coupling with arylboronic acid pinacol esters. In particular, the use of arylboronic acid pinacol esters was found to significantly improve the yield of the reaction.
authors.affiliation: College of Pharmacy, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul, 130-701, Republic of Korea. kimnj@khu.ac.kr.
authors.forename: Jun
authors.initials: J
authors.lastname: Lee
authors.forename: Jihyun
authors.initials: J
authors.lastname: Yu
authors.forename: Seung Hwan
authors.initials: SH
authors.lastname: Son
authors.forename: Jinyuk
authors.initials: J
authors.lastname: Heo
authors.forename: Taelim
authors.initials: T
authors.lastname: Kim
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: An
authors.forename: Kyung-Soo
authors.initials: KS
authors.lastname: Inn
authors.forename: Nam-Jung
authors.initials: NJ
authors.lastname: Kim
mesh_terms: D001895:Boron / Q000737:chemistry*; D002384:Catalysis; D002867:Chromones / Q000737:chemistry*; D047309:Flavones / Q000138:chemical synthesis* / Q000737:chemistry; D006865:Hydrogenation; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*
chemical_list: D002867:Chromones; D047309:Flavones; D009942:Organometallic Compounds; D010165:Palladium; D001895:Boron