title: The Feasibility of Using Large-Scale Text Mining to Detect Adverse Childhood Experiences in a VA-Treated Population.
abstract: Free text in electronic health records resists large-scale analysis. Text records facts of interest not found in encoded data, and text mining enables their retrieval and quantification. The U.S. Department of Veterans Affairs (VA) clinical data repository affords an opportunity to apply text-mining methodology to study clinical questions in large populations. To assess the feasibility of text mining, investigation of the relationship between exposure to adverse childhood experiences (ACEs) and recorded diagnoses was conducted among all VA-treated Gulf war veterans, utilizing all progress notes recorded from 2000-2011. Text processing extracted ACE exposures recorded among 44.7 million clinical notes belonging to 243,973 veterans. The relationship of ACE exposure to adult illnesses was analyzed using logistic regression. Bias considerations were assessed. ACE score was strongly associated with suicide attempts and serious mental disorders (ORs = 1.84 to 1.97), and less so with behaviorally mediated and somatic conditions (ORs = 1.02 to 1.36) per unit. Bias adjustments did not remove persistent associations between ACE score and most illnesses. Text mining to detect ACE exposure in a large population was feasible. Analysis of the relationship between ACE score and adult health conditions yielded patterns of association consistent with prior research.
authors.affiliation: Health Services Research and Development Service, VA Puget Sound Health Care System, Seattle, Washington, USA.|Departments of Psychiatry and Behavioral Sciences and Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington, USA.
authors.forename: Kenric W
authors.initials: KW
authors.lastname: Hammond
authors.affiliation: Department of Anesthesia, VA Puget Sound Health Care System, Seattle, Washington, USA.|Department of Anesthesia, University of Washington, Seattle, Washington, USA.
authors.forename: Alon Y
authors.initials: AY
authors.lastname: Ben-Ari
authors.affiliation: Health Services Research and Development Service, VA Puget Sound Health Care System, Seattle, Washington, USA.
authors.forename: Ryan J
authors.initials: RJ
authors.lastname: Laundry
authors.affiliation: Health Services Research and Development Service, VA Puget Sound Health Care System, Seattle, Washington, USA.|Seattle Epidemiologic Research and Information Center, Seattle, Washington, USA.|Department of Medicine, University of Washington, Seattle, Washington, USA.
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Boyko
authors.affiliation: Health Services Research and Development Service, George A. Whalen VA Medical Center, Salt Lake City, Utah, USA.|Departments of Medicine and Biomedical Informatics, University of Utah, Salt Lake City, Utah, USA.
authors.forename: Matthew H
authors.initials: MH
authors.lastname: Samore
mesh_terms: D000328:Adult; D054523:Adult Survivors of Child Abuse / Q000523:psychology* / Q000706:statistics & numerical data; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease / Q000453:epidemiology*; D015897:Comorbidity; D057225:Data Mining / Q000379:methods; D057286:Electronic Health Records / Q000458:organization & administration / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014481:United States / Q000453:epidemiology; D014728:Veterans / Q000523:psychology* / Q000706:statistics & numerical data; D058014:Veterans Health / Q000706:statistics & numerical data*