title: Wegner's granulomatosis developing for the first time in a patient eight years after starting maintenance hemodialysis.
abstract: Wegener's granulomatosis is a serious autoimmune disorder characterized by necrotizing small-vessel vasculitis. It is a multisystem disease that primarily affects the lung and kidneys. Previous studies indicated few relapses of vasculitis after hemodialysis due to uremic immunosuppression. Our case report describes an end-stage renal failure patient who had developed non-caseating lung granulomata with giant cell formation and fibrinoid necrosis of arterial media that is consistent with Wegner's granulomatosis for the first time and eight years after initiation of maintenance hemodialysis. We believe that such a phenomenon has rarely been reported.
authors.forename: Ahmad Ramadan
authors.initials: AR
authors.lastname: Ali
authors.affiliation: Department of Medicine, Faculty of Medicine, Kuwait University, Safat, Kuwait.
authors.forename: Kamel
authors.initials: K
authors.lastname: El-Reshaid
mesh_terms: D000328:Adult; D015897:Comorbidity; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology*; D006435:Renal Dialysis; D014057:Tomography, X-Ray Computed