title: Tailoring properties of porous Poly (vinylidene fluoride) scaffold through nano-sized 58s bioactive glass.
abstract: The biological properties of porous poly (vinylidene fluoride) (PVDF) scaffolds fabricated by selective laser sintering were tailored through nano-sized 58s bioactive glass. The results showed that 58s bioactive glass distributed evenly in the PVDF matrix. There were some exposed particles on the surface which provided attachment sites for biological response. It was confirmed that the scaffolds had highly bioactivity by the formation of bone-like apatite in simulated body fluid. And the bone-like apatite became dense with the increase in 58s bioactive glass and culture time. Moreover, the scaffolds were suitable for cell adhesion and proliferation compared with the PVDF scaffolds without 58s bioactive glass. The research showed that the PVDF/58s bioactive glass scaffolds had latent application in bone tissue engineering.
authors.affiliation: a State Key Laboratory of High Performance Complex Manufacturing , Central South University , Changsha , China.
authors.forename: Cijun
authors.initials: C
authors.lastname: Shuai
authors.affiliation: a State Key Laboratory of High Performance Complex Manufacturing , Central South University , Changsha , China.
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.affiliation: a State Key Laboratory of High Performance Complex Manufacturing , Central South University , Changsha , China.
authors.forename: Pei
authors.initials: P
authors.lastname: Feng
authors.affiliation: a State Key Laboratory of High Performance Complex Manufacturing , Central South University , Changsha , China.
authors.forename: Chengde
authors.initials: C
authors.lastname: Gao
authors.affiliation: b State Key Laboratory of Powder Metallurgy , Central South University , Changsha , China.
authors.forename: Xiong
authors.initials: X
authors.lastname: Shuai
authors.affiliation: c Department of Orthopedics , The Second Xiangya Hospital, Central South University , Changsha , China.
authors.forename: Tao
authors.initials: T
authors.lastname: Xiao
authors.affiliation: c Department of Orthopedics , The Second Xiangya Hospital, Central South University , Changsha , China.
authors.forename: Youwen
authors.initials: Y
authors.lastname: Deng
authors.affiliation: d School of Basic Medical Science , Central South University , Changsha , China.|e Hunan Provincial Tumor Hospital and the Affiliated Tumor Hospital of Xiangya School of Medicine, Central South University , Changsha , China.
authors.forename: Shuping
authors.initials: S
authors.lastname: Peng
authors.affiliation: f College of Chemistry, Xiangtan University , Xiangtan , China.
authors.forename: Ping
authors.initials: P
authors.lastname: Wu
mesh_terms: D001031:Apatites / Q000737:chemistry; D018786:Bone Substitutes / Q000138:chemical synthesis / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival; D005898:Glass / Q000737:chemistry*; D006801:Humans; D007834:Lasers; D008422:Materials Testing; D049329:Nanostructures / Q000737:chemistry*; D011145:Polyvinyls / Q000737:chemistry*; D016062:Porosity; D017550:Spectroscopy, Fourier Transform Infrared; D054457:Tissue Scaffolds / Q000737:chemistry*; D014961:X-Ray Diffraction; D005465:Fluorocarbon Polymers
chemical_list: D001031:Apatites; D018786:Bone Substitutes; D011145:Polyvinyls; C448994:bioactive glass 58S; C024865:polyvinylidene fluoride; D005465:Fluorocarbon Polymers
keywords: 58s bioactive glass; PVDF; bioactivity; scaffolds; selective laser sintering