title: On the Role of the Blood Vessel Endothelial Microvilli in the Blood Flow in Small Capillaries.
abstract: Endothelial microvilli that protrude into the capillary lumen, although invisible in the optical microscopy, may play an important role in the blood flow control in the capillaries. Because of the plug effects, the width of the gap between the capillary wall and the blood cell is especially critical for the blood flow dynamics in capillaries, while microvilli located on the capillary wall can easily control the velocity of the blood flow. We report that microvilli in the capillaries of different vertebrate species have similar characteristics and density, suggesting similarities between the respective regulation mechanisms. A simplified physical model of the capillary effective diameter control by the microvilli is presented.
authors.affiliation: Department of Physics, University of Puerto Rico (UPR), San Juan, PR 00931, USA.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Makarov
authors.affiliation: Department of Neuroscience, Central University of Caribbean (UCC), Bayamon, PR 00960, USA.
authors.forename: Lidia
authors.initials: L
authors.lastname: Zueva
authors.affiliation: Department of Physiology, Central University of Caribbean (UCC), Bayamon, PR 00960, USA.
authors.forename: Priscila
authors.initials: P
authors.lastname: Sanabria
authors.affiliation: Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences (UAMS), Little Rock, AR 72205, USA.
authors.forename: William Dave
authors.initials: WD
authors.lastname: Wessinger
authors.affiliation: Department of Vertebrates Zoology, Lomonosov Moscow State University (MSU), Moscow 119234, Russia.
authors.forename: Tatiana
authors.initials: T
authors.lastname: Golubeva
authors.affiliation: Faculty of Sciences and Technology, University of Algarve (UAlg), 8005-139 Faro, Portugal.
authors.forename: Igor
authors.initials: I
authors.lastname: Khmelinskii
authors.affiliation: Department of Physiology, Central University of Caribbean (UCC), Bayamon, PR 00960, USA.
authors.forename: Mikhail
authors.initials: M
authors.lastname: Inyushin