title: Why Stop Now? Extended and Continuous Regimens of Combined Hormonal Contraceptive Methods.
abstract: Combined hormonal contraceptives (CHCs) have traditionally been prescribed in 28-day cycles, with 21 days of active hormones followed by a 7-day hormone-free interval. Extended and continuous CHC regimens, defined as regimens with greater than 28 days of active hormones, offer many benefits, including a decrease in estrogen-withdrawal symptoms and likely greater efficacy because of more reliable ovulation suppression. Bleeding profiles are favorable, and unscheduled bleeding decreases over time with these regimens. Extended and continuous regimens of combined oral contraceptives and the contraceptive vaginal ring are safe and have high user acceptability and satisfaction. However, despite numerous benefits, extended and continuous CHC regimens are underused.
authors.affiliation: Department of Obstetrics and Gynecology, University of Washington, 1959 Northeast Pacific Street, Box 356460, Seattle, WA 98195, USA. Electronic address: lsbenson@uw.edu.
authors.forename: Lyndsey S
authors.initials: LS
authors.lastname: Benson
authors.affiliation: Department of Obstetrics and Gynecology, University of Washington, 1959 Northeast Pacific Street, Box 356460, Seattle, WA 98195, USA.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Micks
mesh_terms: D000328:Adult; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage*; D003278:Contraceptives, Oral, Hormonal / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D005193:Family Planning Services; D005260:Female; D006801:Humans; D007436:Intrauterine Devices, Medicated / Q000706:statistics & numerical data*; D008597:Menstrual Cycle / Q000187:drug effects* / Q000502:physiology; D008598:Menstruation / Q000187:drug effects / Q000502:physiology; D017060:Patient Satisfaction / Q000706:statistics & numerical data; D057968:Transdermal Patch / Q000706:statistics & numerical data*; D014481:United States; D016903:Drug Monitoring
chemical_list: D003277:Contraceptives, Oral, Combined; D003278:Contraceptives, Oral, Hormonal
keywords: Bleeding profile with contraception; Combined hormonal contraception; Combined oral contraceptive pills; Continuous contraceptive use; Contraceptive transdermal patch; Contraceptive vaginal ring; Extended contraceptive use; Ovulation suppression