title: FGFR1OP2-FGFR1 induced myeloid leukemia and T-cell lymphoma in a mouse model.
authors.affiliation: GRU Cancer Center, Georgia Regents University, Augusta, GA, USA.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Qin
authors.affiliation: GRU Cancer Center, Georgia Regents University, Augusta, GA, USA.
authors.forename: Qing
authors.initials: Q
authors.lastname: Wu
authors.affiliation: GRU Cancer Center, Georgia Regents University, Augusta, GA, USA.
authors.forename: John K
authors.initials: JK
authors.lastname: Cowell
authors.affiliation: GRU Cancer Center, Georgia Regents University, Augusta, GA, USA mren@gru.edu.
authors.forename: Mingqiang
authors.initials: M
authors.lastname: Ren
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000378:metabolism / Q000473:pathology; D001853:Bone Marrow / Q000378:metabolism / Q000473:pathology; D016026:Bone Marrow Transplantation; D003598:Cytoskeletal Proteins / Q000235:genetics* / Q000378:metabolism; D004195:Disease Models, Animal; D015972:Gene Expression Regulation, Neoplastic; D006412:Hematopoietic Stem Cells / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000235:genetics* / Q000401:mortality / Q000473:pathology; D008099:Liver / Q000378:metabolism / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000150:complications / Q000235:genetics* / Q000401:mortality / Q000473:pathology; D008562:Membrane Glycoproteins / Q000235:genetics / Q000378:metabolism; D051379:Mice; D008822:Mice, Transgenic; D015514:Oncogene Proteins, Fusion / Q000235:genetics* / Q000378:metabolism; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000235:genetics / Q000378:metabolism; D051496:Receptor, Fibroblast Growth Factor, Type 1 / Q000235:genetics* / Q000378:metabolism; D051881:Receptor, Notch1 / Q000235:genetics / Q000378:metabolism; D000071656:Receptor, Notch3 / Q000235:genetics / Q000378:metabolism; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D013154:Spleen / Q000378:metabolism / Q000473:pathology; D016019:Survival Analysis; D013601:T-Lymphocytes / Q000378:metabolism / Q000473:pathology; D044767:Ubiquitin-Protein Ligases / Q000235:genetics / Q000378:metabolism; D014916:Whole-Body Irradiation
chemical_list: D003598:Cytoskeletal Proteins; C547759:FGFR1OP2 protein, mouse; D008562:Membrane Glycoproteins; C497762:Notch1 protein, mouse; C499373:Notch3 protein, mouse; D015514:Oncogene Proteins, Fusion; D019253:Proto-Oncogene Proteins c-bcl-2; D051881:Receptor, Notch1; D000071656:Receptor, Notch3; D016693:Receptors, Antigen, T-Cell, alpha-beta; C090377:pre-T cell receptor alpha; C052617:Bcl2 protein, mouse; C000606502:DTX3L protein, mouse; D044767:Ubiquitin-Protein Ligases; C496349:Fgfr1 protein, mouse; D051496:Receptor, Fibroblast Growth Factor, Type 1
keywords: acute myeloid leukemia; aggressive non-Hodgkin lymphoma; cytogenetics and molecular genetics