title: [Role of measurement of fractional flow reserve in coronary artery atherosclerosis].
abstract: The paper considers coronary flow in health and coronary flow autoregulation in health and disease. It gives basic methods used to estimate coronary flow reserve in patients with coronary atherosclerosis. The physiological bases for determining fractional flow reserve are presented. Clinical trials investigating the use of fractional flow reserve in patients with coronary heart disease are analyzed.
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: F Yu
authors.initials: FY
authors.lastname: Kopylov
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Bykova
authors.affiliation: Institute of Computational Mathematics, Russian Academy of Sciences, Moscow, Russia; Moscow Institute of Physics and Technology.
authors.forename: Yu V
authors.initials: YV
authors.lastname: Vasilevsky
authors.affiliation: Institute of Computational Mathematics, Russian Academy of Sciences, Moscow, Russia; Moscow Institute of Physics and Technology; Dolgoprudny, Russia ,Institute of Computer Aided Design, Russian Academy of Sciences, Moscow, Russia.
authors.forename: S S
authors.initials: SS
authors.lastname: Simakov
mesh_terms: D003324:Coronary Artery Disease / Q000175:diagnosis / Q000503:physiopathology; D003326:Coronary Circulation; D003331:Coronary Vessels / Q000502:physiology / Q000503:physiopathology; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D003935:Diagnostic Techniques, Cardiovascular; D053805:Fractional Flow Reserve, Myocardial; D006801:Humans; D066230:Patient-Specific Modeling; D015203:Reproducibility of Results