title: Analytical characterization of four new ortho-methoxybenzylated amphetamine-type designer drugs.
abstract: In a seizure of German custom authorities four N-(ortho-methoxybenzyl)amines with amphetamine partial structure were obtained as pure compounds: N-(ortho-methoxybenzyl)-3,4-dimethoxyamphetamine (3,4-DMA-NBOMe (1)), N-(ortho-methoxybenzyl)-4-ethylamphetamine (4-EA-NBOMe (2)), N-(ortho-methoxybenzyl)-4-methylmethamphetamine (4-MMA-NBOMe (3)), and N-(ortho-methoxybenzyl)-5-(2-aminopropyl)benzofuran (5-APB-NBOMe (4)). The compounds have been detected in Germany for the first time and no analytical data had been previously published. Mass spectrometric (MS), infrared (IR) spectroscopic, and nuclear magnetic resonance (NMR) spectroscopic data are presented. Copyright © 2015 John Wiley & Sons, Ltd.
authors.affiliation: State Bureau of Criminal Investigation Schleswig-Holstein, Section Narcotics/Toxicology, Mühlenweg 166, D-24116, Kiel, Germany.
authors.forename: Folker
authors.initials: F
authors.lastname: Westphal
authors.affiliation: Pharmaceutical Institute, Christian-Albrechts-University Kiel, Gutenbergstr. 76, 24118, Kiel, Germany.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Girreser
authors.affiliation: Center for Education and Science of the Federal Finance Administration, Laboratory Berlin, Grellstr. 18,24, 10409, Berlin, Germany.
authors.forename: Delia
authors.initials: D
authors.lastname: Waldmüller
mesh_terms: D000662:Amphetamines / Q000737:chemistry*; D001572:Benzofurans / Q000737:chemistry*; D000697:Central Nervous System Stimulants / Q000737:chemistry; D015198:Designer Drugs / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D008694:Methamphetamine / Q000031:analogs & derivatives* / Q000737:chemistry; D010627:Phenethylamines / Q000737:chemistry; D011437:Propylamines / Q000737:chemistry*; D058826:Serotonin 5-HT2 Receptor Agonists / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D015813:Substance Abuse Detection
chemical_list: D000662:Amphetamines; D001572:Benzofurans; D000697:Central Nervous System Stimulants; D015198:Designer Drugs; D010627:Phenethylamines; D011437:Propylamines; D058826:Serotonin 5-HT2 Receptor Agonists; C016434:ethylamphetamine; C014500:3,4-dimethoxyamphetamine; C000608250:5-(2-aminopropyl)benzofuran; D008694:Methamphetamine; C548233:mephedrone
keywords: 3,4-DMA-NBOMe; 4-EA-NBOMe; 4-MMA-NBOMe; 5-APB-NBOMe; GC-MS; IR; NMR; designer drug