title: [VEGETATIVE REACTIONS AS PROGNOSTIC FACTOR IN POSTERIOR FOSSA SURGERY].
abstract: Mortality rate related to posterior fossa tumors resection varies from 1 to 8 percent, according to various authors. It depends on tumor size and its growth characteristics. To determine the physiological acceptability of surgery, physiological significance of vegetative reactions associated with tumors resection has to be assessed. We divide these reactions (centrogenic reactions - CR) into 2 main groups. The first group has a relatively precise morphofunctional structure, similar to the classic reflex arc. They appear due to irritation of local centers or cranial nerves nuclei with mixed motor-vegetative structure. In most cases they are not connected with anatomic damage of CNS structures. The second group of CR is correlated with dysfunction of brain and represents brain s attempt to turn into a new functional state. Their presence should be considered as a functional degradation symptom, which might be even irreversible. Emergence from anesthesia in the operative room is not recommended in this clinical situation. Neurovegetative stabilization should be provided for a period of 6 to 24 hours after tumor resection.
authors.forename: R V
authors.initials: RV
authors.lastname: Nazarov
authors.forename: A N
authors.initials: AN
authors.lastname: Kondrat'ev
mesh_terms: D000762:Anesthesia Recovery Period; D017776:Autonomic Pathways / Q000503:physiopathology*; D003388:Cranial Fossa, Posterior / Q000294:innervation / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D015192:Infratentorial Neoplasms / Q000503:physiopathology / Q000601:surgery*; D008499:Medical Records; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D012018:Reflex / Q000502:physiology*