title: The Relationship Between Serum Endocan Levels With the Presence of Slow Coronary Flow: A Cross-Sectional Study.
abstract: BACKGROUND
  The aim of this study was to investigate the relationship between endocan levels with the presence of slow coronary flow (SCF).
  
  
  METHODS
  In this cross-sectional study, a total of 88 patients, who admitted to our hospital, were included in this study. Of these, 53 patients with SCF and 35 patients with normal coronary flow were included in the final analysis. Coronary flow rates of all patients were determined by the Timi Frame Count (TFC) method.
  
  
  RESULTS
  In correlation analysis, endocan levels revealed a significantly positive correlation with high sensitive C-reactive protein and corrected TFC. In multivariate logistic regression analysis, the endocan levels were found as independently associated with the presence of SCF. Finally, using a cutoff level of 2.3, endocan level predicted the presence of SCF with a sensitivity of 77.2% and specificity of 75.2%.
  
  
  CONCLUSIONS
  In conclusion, our study showed that higher endocan levels were significantly and independently related to the presence of SCF.
authors.affiliation: 1 Cardiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Harun
authors.initials: H
authors.lastname: Kundi
authors.affiliation: 1 Cardiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Gok
authors.affiliation: 1 Cardiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Emrullah
authors.initials: E
authors.lastname: Kiziltunc
authors.affiliation: 2 Biochemistry Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Canan
authors.initials: C
authors.lastname: Topcuoglu
authors.affiliation: 1 Cardiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cetin
authors.affiliation: 1 Cardiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Hulya
authors.initials: H
authors.lastname: Cicekcioglu
authors.affiliation: 1 Cardiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Burcu
authors.initials: B
authors.lastname: Ugurlu
authors.affiliation: 1 Cardiology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Feridun Vasfi
authors.initials: FV
authors.lastname: Ulusoy
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D003324:Coronary Artery Disease / Q000097:blood* / Q000503:physiopathology*; D003326:Coronary Circulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000097:blood*; D011509:Proteoglycans / Q000097:blood*
chemical_list: C101134:ESM1 protein, human; D009363:Neoplasm Proteins; D011509:Proteoglycans
keywords: coronary slow flow; endocan level; endothelial dysfunction