title: Influence of Breastfeeding Time on Levels of Organochlorine Pesticides in Human Milk of a Mexican Population.
abstract: This study was conducted with the objective of determining whether there is a depuration of organochlorine pesticides in breast milk according to breastfeeding time. In total, 171 samples from mothers that lived in the State of Guerrero, Mexico were analyzed. There was a weak negative relationship between pp'DDE (r = -0.216) and Σ-DDT (r = -0.222) concentrations with the days of lactation. In a comparison analysis, a statistically significant decrease of pp'DDT and pp'DDE levels was observed, as well as the Σ-DDT from the first to the fifth week of lactation. A reduction of 0.188 mg/kg lipid of pp'DDE and 0.181 mg/kg lipid of Σ-DDT per week was obtained. HCB, β-HCH and op'DDT concentrations were low and had no major fluctuations between subgroups. The low levels found and the observed reduction in time involve less exposure to the infant to these pollutants. Through this methodology changes in levels of certain organochlorine pesticides in various stages of human milk production may be shown.
authors.affiliation: Secretaría de Salud Guerrero, Laboratorio Estatal de Salud Pública, Vicente Guerrero Esq. J.R. Escudero s/n, 39715, Acapulco, México. chavez_79@hotmail.com.|Universidad Autónoma de Guerrero, Los Pinos s/n, 39640, Acapulco, México. chavez_79@hotmail.com.
authors.forename: Luis A
authors.initials: LA
authors.lastname: Chávez-Almazán
authors.affiliation: Secretaría de Salud Guerrero, Laboratorio Estatal de Salud Pública, Vicente Guerrero Esq. J.R. Escudero s/n, 39715, Acapulco, México.
authors.forename: Jesús
authors.initials: J
authors.lastname: Diaz-Ortiz
authors.affiliation: Secretaría de Salud Guerrero, Laboratorio Estatal de Salud Pública, Vicente Guerrero Esq. J.R. Escudero s/n, 39715, Acapulco, México.
authors.forename: Mario
authors.initials: M
authors.lastname: Alarcón-Romero
authors.affiliation: Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, A.C. Normalistas 800, 44270, Guadalajara, México.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Davila-Vazquez
authors.affiliation: Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Universidad 1001, 62209, Cuernavaca, México.
authors.forename: Hugo
authors.initials: H
authors.lastname: Saldarriaga-Noreña
authors.affiliation: Universidad Autónoma de Guerrero, Los Pinos s/n, 39640, Acapulco, México.
authors.forename: Laura
authors.initials: L
authors.lastname: Sampedro-Rosas
authors.affiliation: Universidad Autónoma de Guerrero, Los Pinos s/n, 39640, Acapulco, México.
authors.forename: Saúl
authors.initials: S
authors.lastname: López-Silva
authors.affiliation: Universidad Autónoma de Guerrero, Los Pinos s/n, 39640, Acapulco, México.
authors.forename: Agustín
authors.initials: A
authors.lastname: Santiago-Moreno
authors.affiliation: Universidad Autónoma de Guerrero, Los Pinos s/n, 39640, Acapulco, México.
authors.forename: José L
authors.initials: JL
authors.lastname: Rosas-Acevedo
authors.affiliation: Instituto de Medicina Forense, Universidad Veracruzana, SS Juan Pablo II s/ns, 94290, Boca del Río, México.
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Waliszewski
mesh_terms: D001942:Breast Feeding; D003634:DDT / Q000032:analysis / Q000378:metabolism; D003633:Dichlorodiphenyl Dichloroethylene / Q000032:analysis / Q000378:metabolism; D005260:Female; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis / Q000378:metabolism*; D008800:Mexico; D008895:Milk, Human / Q000737:chemistry*; D010575:Pesticides / Q000032:analysis / Q000378:metabolism*; D013997:Time Factors
chemical_list: D006843:Hydrocarbons, Chlorinated; D010575:Pesticides; D003633:Dichlorodiphenyl Dichloroethylene; D003634:DDT
keywords: Breast milk; Lactation; Organochlorine pesticides