title: [The use of deoxycholic acid (ATX-101) in aesthetic medicine: A promising treatment].
abstract: ATX-101 is a synthetic derivative from deoxycholic acid, which leads to destruction of adipocytes and to a skin retraction. The US Food and Drug Administration (FDA) has authorized ATX-101 injections for reduction of moderate to severe submental fat. The purpose of this note is to review the data of literature regarding the deoxycholic acid (ATX-101) where a significant difference for the submental fat between the treated group and the placebo group according to clinical and morphological criteria was observed (Refine Study 1 and 2). Side effects of this molecule seems to be limited.
authors.affiliation: Department of Maxillofacial and Plastic & Reconstructive Surgery, Henri Mondor Hospital, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France. Electronic address: barbara.hersant@gmail.com.
authors.forename: B
authors.initials: B
authors.lastname: Hersant
authors.affiliation: Department of Maxillofacial and Plastic & Reconstructive Surgery, Henri Mondor Hospital, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: A
authors.initials: A
authors.lastname: Calmon
authors.affiliation: Department of Maxillofacial and Plastic & Reconstructive Surgery, Henri Mondor Hospital, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Meningaud
mesh_terms: D003840:Deoxycholic Acid / Q000009:adverse effects / Q000627:therapeutic use*; D004954:Esthetics; D063172:Genioplasty / Q000379:methods; D006801:Humans; D015187:Lipectomy / Q000379:methods; D016032:Randomized Controlled Trials as Topic; D013518:Surgery, Plastic / Q000379:methods / Q000639:trends*; D014481:United States
chemical_list: C000599116:ATX-101 compound; D003840:Deoxycholic Acid
keywords: Acide désoxycholique; Deoxycholic acid; Lipolyse; Lipolysis; Liposuccion; Liposuction; Lypolyse; Sous-mentale; Submental