title: Cardiac arrest and therapeutic hypothermia.
abstract: Therapeutic hypothermia for patients who remain comatose following resuscitation from a cardiac arrest improves both survival and neurologic outcomes. Although this therapy has been incorporated into the guidelines for routine post-resuscitation care and has been in clinical use for over a decade, significant questions and controversies remain. In this review, we discuss these questions in the context of the current evidence and provide a practical framework to help guide clinicians.
authors.affiliation: Cardiovascular Division, Department of Medicine, Brigham and Women׳s Hospital, Boston, MA. Electronic address: mgsilverman@partners.org.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Silverman
authors.affiliation: Cardiovascular Division, Department of Medicine, Brigham and Women׳s Hospital, Boston, MA.
authors.forename: Benjamin M
authors.initials: BM
authors.lastname: Scirica
mesh_terms: D001833:Body Temperature Regulation; D006323:Heart Arrest / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects / Q000401:mortality; D020127:Recovery of Function; D012151:Resuscitation / Q000009:adverse effects / Q000401:mortality; D013997:Time Factors; D016896:Treatment Outcome
keywords: Cardiac arrest; targeted temperature management; therapeutic hypothermia