title: [Rhabdomyolysis in a Bipolar Adolescent. Analysis of Associated Factors].
abstract: OBJECTIVE
  To describe a case of rhabdomyolysis associated with the use of quetiapine and lamotrigine in an adolescent treated for bipolar disorder.
  
  
  METHODS
  Description of the clinical case, analysis of the associated factors and a non-systematic review of the relevant literature.
  
  
  RESULTS
  An 18 year old male, with bipolar disorder and treated pharmacologically with quetiapine and lamotrigine, after two weeks of physical activity presents with rhabdomyolysis. Quetiapine and exercise have been associated with rhabdomyolysis. The mediator mechanism of this association has not been found, although it has been established that there is neuromuscular dysfunction and an increase in sarcomere permeability.
  
  
  CONCLUSIONS
  This clinical case allowed the complex interaction between antipsychotic agents and increased physical activity to be observed in a psychiatric adolescent patient, as well as the appearance of a potentially lethal medical complication.
authors.affiliation: Universidad CES, Medellín, Colombia. Electronic address: dianarestrepobernal@gmail.com.
authors.forename: Diana
authors.initials: D
authors.lastname: Restrepo
authors.affiliation: Universidad CES, Medellín, Colombia.
authors.forename: Pablo
authors.initials: P
authors.lastname: Montoya
authors.affiliation: Universidad CES, Medellín, Colombia.
authors.forename: Laura
authors.initials: L
authors.lastname: Giraldo
authors.affiliation: Universidad CES, Medellín, Colombia.
authors.forename: Génesis
authors.initials: G
authors.lastname: Gaviria
authors.affiliation: Clínica El Rosario, Medellín, Colombia.
authors.forename: Catalina
authors.initials: C
authors.lastname: Mejía
mesh_terms: D000293:Adolescent; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy*; D006801:Humans; D000077213:Lamotrigine; D008297:Male; D000069348:Quetiapine Fumarate / Q000009:adverse effects / Q000627:therapeutic use; D012206:Rhabdomyolysis / Q000139:chemically induced*; D014227:Triazines / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D014150:Antipsychotic Agents; D014227:Triazines; D000069348:Quetiapine Fumarate; D000077213:Lamotrigine
keywords: Antipsicóticos; Antipsychotic agents; Bipolar disorder; Ejercicio; Exercise; Rabdomiolisis; Rhabdomyolysis; Trastorno bipolar