title: Inverted Internal Limiting Membrane Insertion for Macular Hole-Associated Retinal Detachment in High Myopia.
abstract: OBJECTIVE
  To investigate the surgical outcomes of inverted internal limiting membrane (ILM) insertion in macular hole (MH)-associated retinal detachment (RD) in high myopia.
  
  
  METHODS
  Retrospective, interventional, consecutive case series.
  
  
  METHODS
  This study was conducted at 2 medical centers. Consecutive cases of highly myopic eyes with MH-associated RD were included. Forty eyes were divided into 2 groups: Group 1 (20 eyes) received vitrectomy, ILM peeling within the arcade area, and air-fluid exchange, and Group 2 (20 eyes) received vitrectomy, inverted ILM inserted into the macular hole, and air-fluid exchange. Optical coherence tomography was used to observe the closure of the macular hole. Corrected visual acuity (VA) was also recorded. Two-sample t test and Mann-Whitney U test were used for statistical analysis to compare differences between the 2 groups.
  
  
  RESULTS
  MH was closed in 35% of the eyes in Group 1 and in all eyes in Group 2 (P < .001). Significant improvement in VA in logarithm of minimal angle of resolution (logMAR) was achieved in both groups. There was no difference in the initial, final, or improvement of logMAR VA in the 2 groups.
  
  
  CONCLUSIONS
  Inverted ILM insertion into a macular hole effectively helps close the macular hole in MH-associated RD in high myopia. This may prevent the possible re-detachment from the MH. A prospective study with a larger number of cases and longer follow-up may help validate our findings.
authors.affiliation: Department of Ophthalmology, Changhua Christian Hospital, Changhua City, Taiwan; College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: San-Ni
authors.initials: SN
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan; College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address: chungmay@ntu.edu.tw.
authors.forename: Chung-May
authors.initials: CM
authors.lastname: Yang
mesh_terms: D000368:Aged; D001485:Basement Membrane / Q000637:transplantation*; D058450:Endotamponade; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D012167:Retinal Perforations / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy