title: Gold-Based Nanomaterials for Applications in Nanomedicine.
abstract: In this review, an overview of the current state-of-the-art of gold-based nanomaterials (Au NPs) in medical applications is given. The unique properties of Au NPs, such as their tunable size, shape, and surface characteristics, optical properties, biocompatibility, low cytotoxicity, high stability, and multifunctionality potential, among others, make them highly attractive in many aspects of medicine. First, the preparation methods for various Au NPs including functionalization strategies for selective targeting are summarized. Second, recent progresses on their applications, ranging from the diagnostics to therapeutics are highlighted. Finally, the rapidly growing and promising field of gold-based theranostic nano-platforms is discussed. Considering the great body of existing information and the high speed of its renewal, we chose in this review to generalize the data that have been accumulated during the past few years for the most promising directions in the use of Au NPs in current medical research.
authors.affiliation: Fachbereich Physik, Philipps Universität Marburg, 35037, Marburg, Germany. ashraf@staff.uni-marburg.de.
authors.forename: Sumaira
authors.initials: S
authors.lastname: Ashraf
authors.affiliation: Fachbereich Physik, Philipps Universität Marburg, 35037, Marburg, Germany.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Pelaz
authors.affiliation: CIC biomaGUNE, San Sebastian, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: del Pino
authors.affiliation: CIC biomaGUNE, San Sebastian, Spain.|Ikerbasque, Basque Foundation for Science, 48011, Bilbao, Spain.
authors.forename: Mónica
authors.initials: M
authors.lastname: Carril
authors.affiliation: Fachbereich Physik, Philipps Universität Marburg, 35037, Marburg, Germany.|Instituto de Ciencia de Materiales de Sevilla, CSIC-University of Seville, 41092, Seville, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: Escudero
authors.affiliation: Fachbereich Physik, Philipps Universität Marburg, 35037, Marburg, Germany.|CIC biomaGUNE, San Sebastian, Spain.
authors.forename: Wolfgang J
authors.initials: WJ
authors.lastname: Parak
authors.affiliation: Fachbereich Physik, Philipps Universität Marburg, 35037, Marburg, Germany.
authors.forename: Mahmoud G
authors.initials: MG
authors.lastname: Soliman
authors.affiliation: Fachbereich Physik, Philipps Universität Marburg, 35037, Marburg, Germany.
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Fachbereich Physik, Philipps Universität Marburg, 35037, Marburg, Germany. carolina.carrillocarrion@physik.uni-marburg.de.
authors.forename: Carolina
authors.initials: C
authors.lastname: Carrillo-Carrion
mesh_terms: D006046:Gold / Q000737:chemistry*; D050997:Nanomedicine; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D006046:Gold
keywords: Diagnostics; Gold nanoparticles; Nanomedicine; Theranostics; Therapeutics