title: A new pregnane glycoside from Gomphocarpus fruticosus growing in Egypt.
abstract: Phytochemical investigation of Gomphocarpus fruticosus (L.) Ait. of Egyptian origin afforded the new pregnane glycoside lineolon-3-O-[β-D-oleandropyranosyl-(1-4)-β-D-cymaropyranosyl-(1-4)-β-D-cymaropyranoside], along with six known compounds. The structures of the isolated compounds were elucidated on the basis of extensive spectroscopic evidences derived from 1D, 2D NMR experiments, mass spectrometry and by comparing their physical and spectroscopic data to literature. These included the triterpenoids 3β-taraxerol, 3β-taraxerol acetate and betulinic acid, which are identified for the first time in G. fruticosus and the cardenolides uzarigenin, gomphoside and calotropin.
authors.affiliation: a Faculty of Pharmacy, Department of Pharmacognosy , Mansoura University , Mansoura , Egypt.
authors.forename: Amani M
authors.initials: AM
authors.lastname: Marzouk
authors.affiliation: b Faculty of Pharmacy, Department of Pharmacognosy , 6th of October University , 6th of October City , Egypt.
authors.forename: Samir M
authors.initials: SM
authors.lastname: Osman
authors.affiliation: a Faculty of Pharmacy, Department of Pharmacognosy , Mansoura University , Mansoura , Egypt.
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Gohar
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D004534:Egypt; D006027:Glycosides / Q000032:analysis* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis; D011278:Pregnanes / Q000032:analysis* / Q000302:isolation & purification
chemical_list: D006027:Glycosides; D010936:Plant Extracts; D011278:Pregnanes; C000611800:lineolon-3-O-(beta-D-oleandropyranosyl-(1-4)-beta-D-cymaropyranosyl-(1-4)-beta-D-cymaropyranoside; C574437:pregnane glycoside
keywords: Apocynaceae; Asclepiadoideae; Gomphocarpus fruticosus, ; cardenolides; gomphofruticososide; pregnane glycosides; triterpenoids