title: Effects of Implantable Collamer Lens V4c Placement on Iridocorneal Angle Measurements by Fourier-Domain Optical Coherence Tomography.
abstract: OBJECTIVE
  To assess by Fourier-domain optical coherence tomography (FDOCT) changes produced in iridocorneal angle measurements in patients undergoing Visian Implantable Collamer Lens (ICL) V4c (STAAR Surgical AG) placement.
  
  
  METHODS
  Prospective interventional case series.
  
  
  METHODS
  In 50 eyes of 25 myopic subjects consecutively scheduled for ICL implant, FDOCT (RTVue; Optovue Inc) iridocorneal angle measurements were made before and 1 and 3 months after surgery. Trabecular-iris angle (TIA) and angle opening distance 500 μm anterior to the scleral spur (AOD500) were compared among the quadrants nasal, temporal, and inferior, and correlations with ocular variables including lens vault were examined.
  
  
  RESULTS
  Preoperative TIA was 48.7 ± 8.7, 48.2 ± 8.7, and 48.7 ± 9.3 degrees for the nasal, temporal, and inferior quadrants, with no differences (P = 1.000). Following ICL implant, corresponding values fell to 31.2 ± 11.5, 30.0 ± 10.7, and 29.7 ± 8.1 degrees at 1 month postsurgery, indicating angle narrowing of 34%-42%, and to 30.6 ± 12.3, 30.1 ± 11.9, and 29.8 ± 12.3 degrees, respectively, at 3 months postsurgery. Angle measurements failed to vary between 1 month and 3 months postsurgery (P = .481). In 8 eyes, iridotrabecular contact attributable to surgery was observed. One month after surgery, vault measurements correlated with TIA (R = -.309; P = .048). Six variables were identified as predictors of TIA at 1 month postsurgery (R(2) = .907).
  
  
  CONCLUSIONS
  Although considerable angle narrowing was detected 1 month after ICL V4c implant, this narrowing remained stable at 3 months postsurgery. Factors predictive of TIA could serve to identify suitable candidates for ICL placement.
authors.affiliation: Department of Ophthalmology, Clínico San Carlos University Hospital, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain; Centro Internacional de Oftalmología Avanzada, Madrid, Spain. Electronic address: jfvigo@hotmail.com.
authors.forename: José Ignacio
authors.initials: JI
authors.lastname: Fernández-Vigo
authors.affiliation: Centro Internacional de Oftalmología Avanzada, Madrid, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Macarro-Merino
authors.affiliation: Centro Internacional de Oftalmología Avanzada, Madrid, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Fernández-Vigo
authors.affiliation: Centro Internacional de Oftalmología Avanzada, Madrid, Spain; Department of Ophthalmology, Extremadura University, Badajoz, Spain.
authors.forename: José Ángel
authors.initials: JÁ
authors.lastname: Fernández-Vigo
authors.affiliation: Department of Ophthalmology, Clínico San Carlos University Hospital, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
authors.forename: José María
authors.initials: JM
authors.lastname: Martínez-de-la-Casa
authors.affiliation: Department of Preventive Medicine, Clínico San Carlos University Hospital, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Fernández-Pérez
authors.affiliation: Department of Ophthalmology, Clínico San Carlos University Hospital, Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
authors.forename: Julián
authors.initials: J
authors.lastname: García-Feijóo
mesh_terms: D000328:Adult; D003315:Cornea / Q000473:pathology*; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D007498:Iris / Q000473:pathology*; D019654:Lens Implantation, Intraocular; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011446:Prospective Studies; D041623:Tomography, Optical Coherence; D014129:Trabecular Meshwork / Q000473:pathology; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult