title: [Obsessive-compulsive Disorder: Prevalence, Comorbidity and Remission from the Ages of 20 to 50].
abstract: Individuals with obsessive-compulsive disorder (OCD) experience recurrent obsessive and/or compulsive thoughts and behaviours which cause them distress, and significantly impair their daily lives. The disorder is thought to have a chronic course and a low rate of remission, as evidenced by mainly clinical samples. Longitudinal psychiatric epidemiological studies are few and far between. This article presents the findings relating to OCD from one such study, the Zurich Study: OCD defined according to DSM-5 criteria had a high prevalence rate and frequently a chronic course but it had a long-term remission rate of almost 60%, which is higher than hitherto believed. OCD was generally highly comorbid with other disorders and particularly closely associated with social phobia.
authors.affiliation: 1 Klinik für Psychiatrie, Psychotherapie und Psychosomatik, Psychiatrische Universitätsklinik Zürich.
authors.forename: Jules
authors.initials: J
authors.lastname: Angst
authors.affiliation: 2 Klinik für Psychiatrie und Psychotherapie, Universitätsspital Zürich, Universität Zürich.
authors.forename: Michael
authors.initials: M
authors.lastname: Rufer
authors.affiliation: 3 Department of Psychiatry, National OCDs Specialist Centre, Hertfordshire Partnership NHS Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, United Kingdom.|4 Postgraduate Medical School, University of Hertfordshire, College Lane, Hatfield, United Kingdom.|5 Department of Psychiatry and Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge, United Kingdom.
authors.forename: Naomi
authors.initials: N
authors.lastname: Fineberg
authors.affiliation: 1 Klinik für Psychiatrie, Psychotherapie und Psychosomatik, Psychiatrische Universitätsklinik Zürich.
authors.forename: Vladeta
authors.initials: V
authors.lastname: Ajdacic-Gross
authors.affiliation: 6 Collegium Helveticum, a Joint Research Institute between the University of Zurich & ETH Zurich.|7 Laboratory of Neuroscience (LIM 27), Institute of Psychiatry, University of São Paulo, São Paulo, Brazil.
authors.forename: Wulf
authors.initials: W
authors.lastname: Rössler
mesh_terms: D000328:Adult; D015897:Comorbidity; D003430:Cross-Sectional Studies; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D011379:Prognosis; D013557:Switzerland; D055815:Young Adult
keywords: Epidemiologie; Komorbidität; Verlauf; Zwang; comorbidity; comorbidité; compulsion; course; déroulement; epidemiology; obsessive-compulsive disorder; épidémiologie