title: A first reported case of clear cell carcinoma associated with delayed extrusion of midurethral tape.
abstract: We present the first reported case of clear cell carcinoma associated with a midurethral tape (MUT), the possible hypotheses and the management pitfalls we encountered. We report a 58-year-old woman who presented with symptoms of urinary tract infection and acute retention of urine associated with vaginal tape exposure 10 years after placement of an inside-out transobturator tape. She subsequently had a partial transobturator tape excision and a diagnostic cystoscopy, which revealed inflammatory changes within the urethra. Postoperatively, her symptoms persisted and the vaginal epithelium healed poorly. A biopsy of the friable tissue reported clear cell carcinoma. Imaging showed a locally invasive periurethral mass and bony and lymphatic metastases. This was treated with palliative radiation therapy. She was still receiving palliative care 5 months after the initial surgery.
authors.affiliation: Department of Obstetrics and Gynaecology, National University Health System, 1E Kent Ridge Road, Singapore, 119228, Singapore. harvard_zj_lin@nuhs.edu.sg.
authors.forename: Harvard Zhenjia
authors.identifier: http://orcid.org/0000-0003-4577-0052
authors.initials: HZ
authors.lastname: Lin
authors.affiliation: Department of Urology, National University Health System, Singapore, Singapore.
authors.forename: Fiona Meiwen
authors.initials: FM
authors.lastname: Wu
authors.affiliation: Department of Obstetrics and Gynaecology, National University Health System, 1E Kent Ridge Road, Singapore, 119228, Singapore.
authors.forename: Jeffrey Jen Hui
authors.initials: JJ
authors.lastname: Low
authors.affiliation: Department of Pathology, National University Health System, Singapore, Singapore.
authors.forename: Kotamma
authors.initials: K
authors.lastname: Venkateswaran
authors.affiliation: Department of Obstetrics and Gynaecology, National University Health System, 1E Kent Ridge Road, Singapore, 119228, Singapore.
authors.forename: Roy Kwok Weng
authors.initials: RK
authors.lastname: Ng
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D053825:Suburethral Slings / Q000009:adverse effects*; D014625:Vaginal Neoplasms / Q000209:etiology*
keywords: Clear cell carcinoma; Midurethral tape; Tape extrusion; Transobturator tape