title: Challenges in the Medical and Surgical Management of Chronic Inflammatory Bowel Disease.
abstract: Inflammatory bowel disease patients will likely come to the surgeon's attention at some point in their course of disease, and they present several unique anatomic, metabolic, and physiologic challenges. Specific and well-recognized complications of chronic Crohn disease and ulcerative colitis are presented as well as an organized and evidence-based approach to the medical and surgical management of such disease sequelae. Topics addressed in this article include intestinal fistula and short bowel syndrome, pouch complications, and deep venous thrombosis with emphasis placed on optimization of the patient's physiologic state for best outcomes.
authors.affiliation: Section of Colon & Rectal Surgery, Department of Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St Louis, MO 63110, USA.
authors.forename: Ellen H
authors.initials: EH
authors.lastname: Bailey
authors.affiliation: Section of Colon & Rectal Surgery, Department of Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St Louis, MO 63110, USA. Electronic address: GLASGOWS@WUDOSIS.WUSTL.EDU.
authors.forename: Sean C
authors.initials: SC
authors.lastname: Glasgow
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003082:Colectomy / Q000009:adverse effects*; D039021:Colonic Pouches / Q000009:adverse effects; D006801:Humans; D007081:Ileostomy / Q000009:adverse effects; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000188:drug therapy* / Q000601:surgery*; D007412:Intestinal Fistula / Q000209:etiology / Q000517:prevention & control; D012778:Short Bowel Syndrome / Q000209:etiology / Q000517:prevention & control; D020246:Venous Thrombosis / Q000209:etiology / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents
keywords: Crohn's disease; Intestinal failure; Intestinal fistula; Intestinal pouch complications; Ulcerative colitis; Venothromboembolism