title: Comparative Study of a Novel Biochemical Assay, the Rapidec Carba NP Test, for Detecting Carbapenemase-Producing Enterobacteriaceae.
abstract: The novel biochemical test, the Rapidec Carba NP (RCNP), was evaluated using carbapenemase- and non-carbapenemase-producing Enterobacteriaceae isolates. The RCNP test was compared with the Carba NP test (CNP) and the modified Hodge test. Compared to the CNP test, the RCNP test had identical sensitivity (96%) and lower specificity (93% versus 100%). The medium used to culture the isolates significantly affected test sensitivity and specificity. The RCNP test was quicker and easier to perform than the other tests.
authors.affiliation: Division of Epidemiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel zivl@tlvmc.gov.il yehudac@tlvmc.gov.il.
authors.forename: Ziv
authors.initials: Z
authors.lastname: Lifshitz
authors.affiliation: Division of Epidemiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Amos
authors.initials: A
authors.lastname: Adler
authors.affiliation: Division of Epidemiology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel zivl@tlvmc.gov.il yehudac@tlvmc.gov.il.
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Carmeli
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis*; D001431:Bacteriological Techniques / Q000379:methods / Q000592:standards; D004755:Enterobacteriaceae / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis* / Q000382:microbiology*; D006801:Humans; D016133:Polymerase Chain Reaction; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase