title: [Affective syndromes in liver transplant recipients: ¿mediated neurotoxicity immunosuppressive?].
abstract: BACKGROUND
  The onset of affective and psychotic in liver transplant patients symptoms, raises the need to explore the possible etiologies of mental symptoms.
  
  
  METHODS
  Case report and literature review.
  
  
  RESULTS
  Four clinical cases of patients undergoing orthotopic liver transplantation, who in the early post transplant showed affective symptoms, delusions and psychomotor agitation for which they needed psychiatric hospitalization and treatment with psychotropic drugs are presented. Three of the patients had clinical improvement and one patient died by suicide.
  
  
  CONCLUSIONS
  The development of mental symptoms in the post-transplant period opens the possibility of considering the secondary organic mental disorder a basic condition.
  
  
  CONCLUSIONS
  The adverse drug reaction may explain affective mental disorders in these four cases were reported.
authors.affiliation: Médica Psiquiatra de Enlace, Docente Universidad CES, Estudiante de Maestría en Epidemiología Universidad CES, Medellín, Colombia. Electronic address: dianarestrepobernal@gmail.com.
authors.forename: Diana Patricia
authors.initials: DP
authors.lastname: Restrepo
authors.affiliation: Médica Psiquiatra, Hospital Universitario San Vicente Fundación, Medellín, Colombia.
authors.forename: Alejandra
authors.initials: A
authors.lastname: Tamayo
mesh_terms: D000328:Adult; D005260:Female; D006760:Hospitalization; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D008875:Middle Aged; D020258:Neurotoxicity Syndromes / Q000209:etiology*; D011619:Psychotropic Drugs / Q000627:therapeutic use; D013405:Suicide / Q000523:psychology
chemical_list: D007166:Immunosuppressive Agents; D011619:Psychotropic Drugs
keywords: Behavior; Conducta; Depresión; Depression; Immunosuppression; Inmunosupresores; Liver transplantation; Mania; Neurotoxicity syndromes; Síndromes de neurotoxicidad; Trasplante de hígado; Trastorno maniaco