title: Profile of acute kidney injury after open heart surgeries in a tertiary care hospital.
abstract: Our objective is to determine the incidence, etiology, risk factors and outcome of acute kidney injury (AKI) after open heart surgery. A prospective study was conducted on 62 patients who underwent open heart surgery and were followed-up for the development of AKI and to determine its incidence, etiology and outcome. Post-operative AKI was considered when the post-operative serum creatinine was >1.5 mg/dL or there was doubling of serum creatinine above the baseline (pre-operative) with a prior normal renal function. The incidence of AKI in the post-operative period in our study was 17.7%. The common etiological factors for AKI in our study were sepsis, hypotension, prolonged need for ventilator and inotropic support and drugs given in the post-operative period. The important risk factors for the development of AKI in the post-operative period were hypertension, diabetes mellitus, gout, prolonged total bypass time and prolonged aortic cross-clamp time. The overall mortality in our study subjects was 11.3% (seven of 62 died) and the mortality in the patients who developed post-operative AKI was 71.4%.
authors.forename: Fayaz A
authors.initials: FA
authors.lastname: Rather
authors.forename: Saleem M
authors.initials: SM
authors.lastname: Najar
authors.affiliation: Department of Nephrology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
authors.forename: Hilal A
authors.initials: HA
authors.lastname: Malla
authors.forename: A G
authors.initials: AG
authors.lastname: Ahangar
authors.forename: Hilal M
authors.initials: HM
authors.lastname: Bhat
authors.forename: Imtiyaz A
authors.initials: IA
authors.lastname: Wani
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D000293:Adolescent; D000328:Adult; D006348:Cardiac Surgical Procedures; D002648:Child; D002675:Child, Preschool; D003928:Diabetic Nephropathies / Q000453:epidemiology; D005260:Female; D006073:Gout / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D011183:Postoperative Complications / Q000453:epidemiology*; D011446:Prospective Studies; D012307:Risk Factors; D062606:Tertiary Care Centers; D055815:Young Adult