title: Double Asymmetric Induction During the Addition of (RP)-Menthyl Phenyl Phosphine Oxide to Chiral Aldimines.
abstract: P,C-Stereogenic α-amino phosphine oxides were prepared from the addition of (RP )-menthyl phenyl phosphine oxide to chiral aldimines under neat condition at 80 °C in up to 91:9 drC and 99% yields. The diastereoselectivity was mainly induced by chiral phosphorus that showed matched or mismatched induction with (S)- or (R)-aldimines, respectively.
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Shandong, China.
authors.forename: Zhong-Yang
authors.initials: ZY
authors.lastname: Zhou
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Shandong, China.
authors.forename: He
authors.initials: H
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Shandong, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Yao
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Shandong, China.
authors.forename: Jing-Hong
authors.initials: JH
authors.lastname: Wen
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Shandong, China.
authors.forename: Shao-Zhen
authors.initials: SZ
authors.lastname: Nie
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Shandong, China.
authors.forename: Chang-Qiu
authors.initials: CQ
authors.lastname: Zhao
mesh_terms: D002384:Catalysis; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007097:Imines; D009943:Organophosphorus Compounds
keywords: (RP)-menthyl phenyl phosphine oxide; P,C-stereogenic; addition; double asymmetric induction; α-amino tertiary phosphines oxide