title: DNA Microarray Analysis of Estrogen-Responsive Genes.
abstract: DNA microarray is a powerful, non-biased discovery technology that allows the analysis of the expression of thousands of genes at a time. The technology can be used for the identification of differential gene expression, genetic mutations associated with diseases, DNA methylation, single-nucleotide polymorphisms, and microRNA expression, to name a few. This chapter describes microarray technology for the analysis of differential gene expression in response to estrogen treatment.
authors.affiliation: Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, 414 E. Clark St., Vermillion, SD, 57069, USA. Kathleen.Eyster@usd.edu.
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Eyster
mesh_terms: D000818:Animals; D019295:Computational Biology; D030541:Databases, Genetic; D004967:Estrogens / Q000494:pharmacology*; D004997:Ethinyl Estradiol / Q000494:pharmacology*; D005260:Female; D020869:Gene Expression Profiling / Q000379:methods*; D005786:Gene Expression Regulation / Q000187:drug effects*; D020411:Oligonucleotide Array Sequence Analysis; D010052:Ovariectomy; D016133:Polymerase Chain Reaction; D017207:Rats, Sprague-Dawley; D057188:Workflow
chemical_list: D004967:Estrogens; D004997:Ethinyl Estradiol
keywords: DNA microarray; Estrogen; Gene expression