title: Solitary Fibrous Tumor of the Lower Leg: A Rare and Difficult Diagnosis.
abstract: Solitary fibrous tumor (SFT) is a rare neoplasm that commonly originates in the pleura. Extrapleural locations are rare and for this reason sometimes difficult to diagnose. Malignant forms with local recurrence or distant metastases have been reported, also as a consequence of inappropriate treatment. In this article, we report the case of an SFT of the lower leg in a 37-year-old man. Leg SFT is a rare occurrence, and differential diagnosis may be difficult because they can mimic a variety of benign and malignant mesenchymal tumors; immunohistochemical analysis for CD34, CD99, vimentin, and Bcl-2 is necessary. Misdiagnosis carries a significant risk of inadequate removal with subsequent increased risk of recurrence and distant metastases.
authors.affiliation: Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Sicily, Italy; Department of Sciences for Health Promotion, University of Palermo, Palermo, Sicily, Italy; and Department of Plastic and Reconstructive Surgery, Ghent University Hospital, Ghent, Belgium.
authors.forename: Salvatore
authors.initials: S
authors.lastname: D'Arpa
authors.affiliation: Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Sicily, Italy; Department of Sciences for Health Promotion, University of Palermo, Palermo, Sicily, Italy; and Department of Plastic and Reconstructive Surgery, Ghent University Hospital, Ghent, Belgium.
authors.forename: Matteo
authors.initials: M
authors.lastname: Rossi
authors.affiliation: Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Sicily, Italy; Department of Sciences for Health Promotion, University of Palermo, Palermo, Sicily, Italy; and Department of Plastic and Reconstructive Surgery, Ghent University Hospital, Ghent, Belgium.
authors.forename: Luigi
authors.initials: L
authors.lastname: Montesano
authors.affiliation: Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Sicily, Italy; Department of Sciences for Health Promotion, University of Palermo, Palermo, Sicily, Italy; and Department of Plastic and Reconstructive Surgery, Ghent University Hospital, Ghent, Belgium.
authors.forename: Ada Maria
authors.initials: AM
authors.lastname: Florena
authors.affiliation: Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Sicily, Italy; Department of Sciences for Health Promotion, University of Palermo, Palermo, Sicily, Italy; and Department of Plastic and Reconstructive Surgery, Ghent University Hospital, Ghent, Belgium.
authors.forename: Francesco
authors.initials: F
authors.lastname: Moschella
authors.affiliation: Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Sicily, Italy; Department of Sciences for Health Promotion, University of Palermo, Palermo, Sicily, Italy; and Department of Plastic and Reconstructive Surgery, Ghent University Hospital, Ghent, Belgium.
authors.forename: Adriana
authors.initials: A
authors.lastname: Cordova