title: In This Issue. Randomized Controlled Trials in the Era of Big Data.
authors.affiliation: Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: ckieling@ufrgs.br.
authors.forename: Christian
authors.initials: C
authors.lastname: Kieling
mesh_terms: D000293:Adolescent; D001714:Bipolar Disorder / Q000628:therapy*; D002648:Child; D019317:Evidence-Based Medicine; D006801:Humans; D010372:Pediatrics; D010506:Periodicals as Topic; D016032:Randomized Controlled Trials as Topic