title: Relapse of ileus in patients with psychiatric disorders: A 2-year chart review.
abstract: OBJECTIVE
  To explore risk factors for relapse of paralytic ileus in a psychiatric population.
  
  
  METHODS
  We conducted a systematic chart-review to examine two-year relapse rates in psychiatric patients who received treatment for ileus from 2008 to 2012. Binary logistic regression analyses were performed to evaluate associations between sociodemographic and clinical characteristics and relapse of ileus.
  
  
  RESULTS
  Sixty-three subjects (38 women; age, 66.0 ± 11.3 years) were included; 62 subjects recovered from ileus. During the subsequent 2 years, 26 (41.3%) subjects experienced relapse. In the entire sample, relapse of ileus was associated with history of abdominal surgery (P=.03, odds ratio=4.34, 95% CI=1.15-16.42) and duration of psychiatric disorders (P=.02, odds ratio=1.00, 95% CI=1.00-1.00). In a subgroup of 43 subjects with schizophrenia, history of abdominal surgery (P=.01, odds ratio=12.09, 95% CI=1.78-82.15) and age (P=.02, odds ratio=1.12, 95% CI=1.02-1.23) predicted relapse of ileus.
  
  
  CONCLUSIONS
  Since relapse of ileus is common and can be serious in psychiatric patients, special attention is warranted to those who are old, have a history of abdominal surgery or a longer duration of psychiatric disorders to prevent relapse of ileus.
authors.affiliation: Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan; Department of Psychiatry, Tokyo Musashino Hospital, Tokyo, Japan. Electronic address: ryosuke.kitahata.y@gmail.com.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Kitahata
authors.affiliation: Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan; Multimodal Imaging Group - Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada. Electronic address: shinichiro_nakajima@hotmail.com.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Nakajima
authors.affiliation: Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan; Department of Psychiatry, Inokashira Hospital, Tokyo, Japan. Electronic address: takefumi@oak.dti.ne.jp.
authors.forename: Takefumi
authors.initials: T
authors.lastname: Suzuki
authors.affiliation: Multimodal Imaging Group - Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada. Electronic address: plitmaneric@gmail.com.
authors.forename: Eric
authors.initials: E
authors.lastname: Plitman
authors.affiliation: Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan. Electronic address: mimura@a7.keio.jp.
authors.forename: Masaru
authors.initials: M
authors.lastname: Mimura
authors.affiliation: Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan; Geriatric Mental Health Division, Centre for Addiction and Mental Health, Toronto, Canada. Electronic address: hiroyuki.uchida.hu@gmail.com.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Uchida
mesh_terms: D000005:Abdomen / Q000601:surgery; D000367:Age Factors; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy / Q000453:epidemiology*; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D015331:Cohort Studies; D015897:Comorbidity; D003704:Dementia / Q000188:drug therapy / Q000453:epidemiology*; D003865:Major Depressive Disorder / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006801:Humans; D045823:Ileus / Q000453:epidemiology; D007418:Intestinal Pseudo-Obstruction / Q000453:epidemiology*; D053208:Kaplan-Meier Estimate; D016015:Logistic Models; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy / Q000453:epidemiology; D008875:Middle Aged; D016017:Odds Ratio; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D012559:Schizophrenia / Q000188:drug therapy / Q000453:epidemiology*; D013514:Surgical Procedures, Operative; D013997:Time Factors
chemical_list: D014150:Antipsychotic Agents; D018680:Cholinergic Antagonists
keywords: Ileus; Predictor; Psychotropic; Relapse; Schizophrenia