title: Short-Term Effect of Percutaneous Bipolar Continuous Radiofrequency on Sacral Nerves in Patients Treated for Neurogenic Detrusor Overactivity After Spinal Cord Injury: A Randomized Controlled Feasibility Study.
abstract: OBJECTIVE
  To investigate the short-term effects of bipolar radiofrequency applied to sacral nerves to treat neurogenic detrusor overactivity in patients with spinal cord injury.
  
  
  METHODS
  Ten patients with spinal cord injury with neurogenic detrusor overactivity were recruited. These subjects were randomized to two groups: intervention (n=5) and control (n=5), members of which received conventional treatment. Voiding diary, International Consultation on Incontinence Questionnaire (ICIQ) and the urinary incontinence quality of life scale (IQOL) data were obtained and an urodynamic study (UDS) was performed before and after intervention. In the intervention group, percutaneous bipolar continuous radiofrequency (CRF) was performed on both the S2 and S3 nerves in each patient.
  
  
  RESULTS
  In a comparison of daily frequency and number of urinary incontinence and ICIQ and IQOL scores at baseline and at 1 and 3 months after intervention, all variables achieved a significant effect for time (p<0.05). Regarding UDS parameters, pre/post intervention differences between baseline and 3-month post-intervention for volume at maximal detrusor pressure during filling and reflex detrusor volume at first contraction were significantly different between the two groups (p<0.05). However, pre/post intervention differences in maximum cystometric capacity and maximum detrusor pressure during filling were not significant between the two groups (p>0.05).
  
  
  CONCLUSIONS
  Percutaneous bipolar CRF applied to sacral nerves might be an effective therapy for neurogenic overactive bladder that reduces urinary incontinence and improves quality of life.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Korea.
authors.forename: Jin Hyun
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Korea.
authors.forename: Sang Ho
authors.initials: SH
authors.lastname: Ahn
authors.affiliation: Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Korea.
authors.forename: Yun Woo
authors.initials: YW
authors.lastname: Cho
authors.affiliation: Department of Medical Statistics, Catholic University of Daegu School of Medicine, Daegu, Korea.
authors.forename: Sang Gyu
authors.initials: SG
authors.lastname: Kwak
authors.affiliation: Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Korea.
authors.forename: Hyo Sung
authors.initials: HS
authors.lastname: Kim
keywords: Detrusor overactivity; Maximal cystometric capacity; Radiofrequency; Sacral nerves; Urinary incontinence