title: [ANTIBIOTIC RESISTANCE OF ESCHERICHIA COLI OF THE INTESTINAL MICROBIOTA IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER].
abstract: We used clinical bacteriological analysis and high-density DNA-microchips (PhyloChip) to study the quality and the quantity of commensal bacteria of the genus Escherichia in patients with familial mediterraneanfever (periodic disease). The intestinal microbiota of these patients contained a large number of operational taxonomic units of these bacteria. The study of antibiotic resistance of Escherichia coli from the intestinal microbiota in patients with familial mediterranean fever reveald a large number of resistant and multiresistant isolates. Therapy with commercial probiotic Narine (Vitamax-E, Armenia) reduced the number of operational taxonomic units of commensal bacteria and the frequency of multiresistant isiolates. The mechanism of action of Narine probiotic on intestinal bacteria and their resistance to antibiotics is discussed
authors.forename: A Z
authors.initials: AZ
authors.lastname: Pepoyan
authors.forename: M A
authors.initials: MA
authors.lastname: Balayan
authors.forename: N A
authors.initials: NA
authors.lastname: Atrutyunyan
authors.forename: A G
authors.initials: AG
authors.lastname: Grigoryan
authors.forename: V V
authors.initials: VV
authors.lastname: Tsaturyan
authors.forename: A M
authors.initials: AM
authors.lastname: Manvelyan
authors.forename: E
authors.initials: E
authors.lastname: Dilanyan
authors.forename: I
authors.initials: I
authors.lastname: Pitseno
authors.forename: T
authors.initials: T
authors.lastname: Torok
mesh_terms: D000293:Adolescent; D000328:Adult; D019587:Dietary Supplements; D024901:Drug Resistance, Multiple, Bacterial; D004926:Escherichia coli / Q000187:drug effects / Q000302:isolation & purification / Q000502:physiology; D010505:Familial Mediterranean Fever / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D000069196:Gastrointestinal Microbiome / Q000187:drug effects*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D017063:Outcome Assessment, Health Care; D019936:Probiotics / Q000008:administration & dosage*