title: [Can urinary neutrophil gelatinase-associated lipocalin predict acute rejection following deceased donor kidney transplantation?].
abstract: BACKGROUND
  Delayed graft function and acute rejection have negative impact on graft survival.
  
  
  OBJECTIVE
  To asses the predictive value of urinary neutrophil gelatinase-associated lipocalin, which has been found to be a promising biomarker for the diagnosis of acute kidney injury.
  
  
  METHODS
  In this prospective study urinary neutrophil gelatinase-associated lipocalin levels of 27 kidney recipients were measured.
  
  
  RESULTS
  Patients were grouped as follows: group 1, no complication; group 2, rejection; group 3, delayed graft function requiring dialysis; group 4, rejection plus delayed graft function. There were no significant differences between groups 1 and 2, and between groups 3 and 4. Patients in groups 3 and 4 had significantly higher urinary neutrophil gelatinase-associated lipocalin levels as compared to those in groups 3 and 4. There was a paralIel change in urinary neutrophil gelatinase-associated lipocalin levels in groups 1 and 2.
  
  
  CONCLUSIONS
  In these patients urinary neutrophil gelatinase-associated lipocalin levels failed to provide useful information in both cases of normal and impaired function.
authors.affiliation: Transzplantációs és Sebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Baross u. 23., 1082.
authors.forename: Gábor
authors.initials: G
authors.lastname: Telkes
authors.affiliation: Transzplantációs és Sebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Baross u. 23., 1082.
authors.forename: Gábor
authors.initials: G
authors.lastname: Dallos
authors.affiliation: Transzplantációs és Sebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Baross u. 23., 1082.
authors.forename: Marina
authors.initials: M
authors.lastname: Varga
mesh_terms: D000208:Acute Disease; D000209:Acute-Phase Proteins / Q000652:urine*; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000652:urine; D001706:Biopsy; D002102:Cadaver; D003404:Creatinine / Q000097:blood; D005260:Female; D006084:Graft Rejection / Q000175:diagnosis* / Q000652:urine*; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation; D000071068:Lipocalin-2; D054834:Lipocalins / Q000652:urine*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011518:Proto-Oncogene Proteins / Q000652:urine*; D018570:Risk Assessment; D012307:Risk Factors; D018401:Sample Size
chemical_list: D000209:Acute-Phase Proteins; D015415:Biomarkers; C489506:LCN2 protein, human; D000071068:Lipocalin-2; D054834:Lipocalins; D011518:Proto-Oncogene Proteins; D003404:Creatinine
keywords: acute kidney injury; akut vesekárosodás; graft rejection; graftrejekció; kidney transplantation; neutrofil gelatináz asszociálta lipokalin; neutrophil gelatinase-associated lipocalin; vesetranszplantáció