title: [Level of control and treatment adherence of anticoagulation with acenocoumarol in Primary Care].
abstract: OBJECTIVE
  To determine the level of control in treatment compliance in a sample of patients who were treated with acenocoumarol attended in Primary Care settings.
  
  
  METHODS
  Cross-sectional study. Patients with non-valvular atrial fibrillation treated with acenocoumarol were included. The sample size was calculated based on previous studies. Data of patients who possessed International Normalized Ratio (INR) values in last 6 months in medical consult were collected. It was considered that the INR control was inadequate when the percentage of INR values within the therapeutic range was less than 60% in the last 6 months. Assessment of compliance by telephone interview was conducted by the Morisky-Green Test.
  
  
  RESULTS
  One hundred and ninety-one patients, 110 women (57.6%) with an average age of 76.5±9.4 years were included. Seventy-six patients (39.8%) were in therapeutic range (INR: 2-3) and 115 patients (60.2%) were out of range (below 2 the 20.9% and above 3 the 39.3%). Poor control of INR increased to the age of 85 years (<75 years: 57.8%; 75-85 years: 67.6%;>85 years: 61.5%). Ninety patients responded to the compliance questionnaire (78.3%), being compliant 74 (82.2%) and non-compliant 16 (17.8%).
  
  
  CONCLUSIONS
  Six of 10 patients undergoing treatment with acenocoumarol are out of range and nearly 2 of each 10 patients out of range does not accomplish the treatment. We call attention to the need to make a systematically review of adherence in anticoagulated patients attended in Primary Care settings.
authors.affiliation: Centro de Salud Ingeniero Joaquín Benlloch, Valencia, España. Electronic address: javiprecic@gmail.com.
authors.forename: F J
authors.initials: FJ
authors.lastname: Precioso Costa
authors.affiliation: Centro de Salud Ingeniero Joaquín Benlloch, Valencia, España.
authors.forename: M J
authors.initials: MJ
authors.lastname: Larré Muñoz
authors.affiliation: Centro de Salud Ingeniero Joaquín Benlloch, Valencia, España.
authors.forename: F M
authors.initials: FM
authors.lastname: Navarro Ros
authors.affiliation: Centro de Salud Ingeniero Joaquín Benlloch, Valencia, España.
authors.forename: Y A
authors.initials: YA
authors.lastname: Silvero
authors.affiliation: Centro de Salud Ingeniero Joaquín Benlloch, Valencia, España.
authors.forename: L
authors.initials: L
authors.lastname: Garrido Sepúlveda
authors.affiliation: Centro de Salud Ingeniero Joaquín Benlloch, Valencia, España.
authors.forename: J L
authors.initials: JL
authors.lastname: Llisterri Caro
mesh_terms: D000074:Acenocoumarol / Q000627:therapeutic use*; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D003430:Cross-Sectional Studies; D016903:Drug Monitoring; D005260:Female; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D008875:Middle Aged; D011320:Primary Health Care; D013030:Spain
chemical_list: D000925:Anticoagulants; D000074:Acenocoumarol
keywords: Acenocoumarol; Acenocumarol; Atención Primaria; Control; Primary Care