title: Surface modification strategies on mesoporous silica nanoparticles for anti-biofouling zwitterionic film grafting.
abstract: In the past decade, zwitterionic-based anti-biofouling layers had gained much focus as a serious alternative to traditional polyhydrophilic films such as PEG. In the area of assembling silica nanoparticles with stealth properties, the incorporation of zwitterionic surface film remains fairly new but considering that silica nanoparticles had been widely demonstrated as useful biointerfacing nanodevice, zwitterionic film grafting on silica nanoparticle holds much potential in the future. This review will discuss on the conceivable functional chemistry approaches, some of which are potentially suitable for the assembly of such stealth systems.
authors.affiliation: Department of Materials Science, University of Milan-Bicocca, Via R. Cozzi 55, I-20125 Milan Italy; Institute of New Drug Development, China Medical University, No. 91 Hsueh-Shih Road, Taichung 404, Taiwan. Electronic address: yitlung.khung@mail.cmu.edu.tw.
authors.forename: Yit Lung
authors.initials: YL
authors.lastname: Khung
authors.affiliation: Department of Materials Science, University of Milan-Bicocca, Via R. Cozzi 55, I-20125 Milan Italy.
authors.forename: Dario
authors.initials: D
authors.lastname: Narducci
mesh_terms: D057219:Biofouling / Q000517:prevention & control*; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D012822:Silicon Dioxide
keywords: Anti-biofouling; Silica nanoparticles; Zwitterionic films