title: Magnetic resonance elastography (MRE) in cancer: Technique, analysis, and applications.
abstract: Tissue mechanical properties are significantly altered with the development of cancer. Magnetic resonance elastography (MRE) is a noninvasive technique capable of quantifying tissue mechanical properties in vivo. This review describes the basic principles of MRE and introduces some of the many promising MRE methods that have been developed for the detection and characterization of cancer, evaluation of response to therapy, and investigation of the underlying mechanical mechanisms associated with malignancy.
authors.affiliation: Mayo Graduate School, United States. Electronic address: pepin.kay@mayo.edu.
authors.forename: Kay M
authors.initials: KM
authors.lastname: Pepin
authors.affiliation: Department of Radiology, United States. Electronic address: ehman.richard@mayo.edu.
authors.forename: Richard L
authors.initials: RL
authors.lastname: Ehman
authors.affiliation: Department of Radiology, United States. Electronic address: mcgee.kiaran@mayo.edu.
authors.forename: Kiaran P
authors.initials: KP
authors.lastname: McGee
mesh_terms: D000818:Animals; D054459:Elasticity Imaging Techniques / Q000379:methods*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000503:physiopathology
keywords: Clinical applications; Elasticity imaging; Magnetic resonance elastography (MRE); Oncology; Tissue stiffness