title: Akathisia with Erythromycin: Induced or precipitated?
abstract: OBJECTIVE
  A 28-year-old male diagnosed with schizophrenia, maintaining well on Olanzapine, developed akathisia soon after addition of Erythromycin for Pityriasis Rosea. This prompted us to evaluate the relationship of Erythromycin and akathisia.
  
  
  METHODS
  We report the case and the literature focusing on akathisia as a possible adverse event of Erythromycin.
  
  
  RESULTS
  Akathisia resolved after Erythromycin was stopped following 5 days of treatment. Akathisia was possibly induced or precipitated with use of Erythromycin. Possible etiological reasons of this clinically significant association are discussed.
  
  
  CONCLUSIONS
  Erythromycin, by itself, may induce akathisia or precipitate akathisia in individuals by interfering with metabolism of other culprit drugs.
authors.affiliation: Department of Psychiatry and Drug De-addiction, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi, India.
authors.forename: Ankur
authors.initials: A
authors.lastname: Sachdeva
authors.affiliation: Department of Psychiatry and Drug De-addiction, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi, India.
authors.forename: Ruchika
authors.initials: R
authors.lastname: Rathee
keywords: Akathisia; Erythromycin; Induced; Management