title: [Occluding effects of desensitizer containing NovaMin combined with fluor protector on dentinal tubules:an in vitro study].
abstract: OBJECTIVE
  To observe the occlusion effect, acid resistance and abrasion resistance of desensitizer containing NovaMin combined with fluor protector on dentin tubules, in order to provide theoretical basis for clinical treatment of dentin hypersensitivity.
  
  
  METHODS
  Thirty extracted intact and non-carious human premolars for orthodontic treatment were selected and made into 2 mm thick dentin slices. Each slice was cut into 4 parts to form 120 sensitive dentin models and randomly divided into 4 groups (n=30). Distilled water (group A), fluor protector (group B), Ominq desensitizer (group C) and fluor protector combined with Ominq desensitizer (group D)were applied respectively on the exposed dentin surfaces. After immersed in the artificial saliva for 24 h, each group was divided into 3 subgroups randomly to undergo direct observation, acid corrosion and tooth brushing test, then the plugging rate of dentin tubules was statistically analyzed with SPSS 13.0 software package.
  
  
  RESULTS
  Dentin tubules in group A were completely open, while good occluding effects were found in group B, C and D. Among them, group D displayed the best occlusion effect, and ability of acid and abrasion resistance compared with other 3 groups (P<O.01).
  
  
  CONCLUSIONS
  Treatment with desensitizer containing NovaMin combined with fluor protector shows better occluding effects in the dentin tubules and better ability of acid and abrasion resistance.
authors.affiliation: VIP Department, School of Stomatology, China Medical University. Shenyang 110002, Liaoning Province, China.E-mail:chenlv1988@126.com.
authors.forename: Li-wei
authors.initials: LW
authors.lastname: Chen
authors.forename: Shuang
authors.initials: S
authors.lastname: Gu
authors.forename: Xing-ya
authors.initials: XY
authors.lastname: Jia
mesh_terms: D003804:Dentin; D003807:Dentin Sensitivity; D004338:Drug Combinations; D005460:Fluorides, Topical; D005898:Glass; D006801:Humans; D008855:Microscopy, Electron, Scanning; D011140:Polyurethanes; D012464:Saliva, Artificial; D012821:Silanes; D014099:Toothbrushing
chemical_list: D004338:Drug Combinations; D005460:Fluorides, Topical; C510984:NovaMin; D011140:Polyurethanes; D012464:Saliva, Artificial; D012821:Silanes; C022599:Fluor Protector