title: Secondary vasculitis in autoimmune connective tissue diseases.
abstract: OBJECTIVE
  The current review of the vasculitis associated with autoimmune connective tissue diseases is very appropriate and timely, in view of the recently acquired expanding knowledge, over the last decade, on the clinical epidemiology, pathophysiology, and the innovative therapeutic strategies. This review will specifically focus on the clinical presentations of secondary vasculitides, pathophysiology, and their management.
  
  
  RESULTS
  New knowledge on the immunological triggers and pathophysiology of these conditions, in relation to various infections and airborne substances are discussed apart from the novel targeted immunotherapy, which has a direct effect on the outcome and reduction of iatrogenic complications.
  
  
  CONCLUSIONS
  The review will inform the classical nature and pattern of vasculitis secondary to autoimmune diseases with specific reference to targeted immunotherapy.
authors.affiliation: aDepartment of Rheumatology, Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge bRoyal Free London Hospital NHS Foundation Trusts cCentre for Rheumatology and Connective Tissue Disease, UCL Medical School, Royal Free Campus, London, UK.
authors.forename: Kuntal
authors.initials: K
authors.lastname: Chakravarty
authors.forename: Voon H
authors.initials: VH
authors.lastname: Ong
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Denton
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications; D003240:Connective Tissue Diseases / Q000150:complications; D006801:Humans; D014657:Vasculitis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy