title: Clinical PET Myocardial Perfusion Imaging and Flow Quantification.
abstract: Cardiac PET imaging is a powerful tool for the assessment of coronary artery disease. Many tracers with different advantages and disadvantages are available. It has several advantages over single photon emission computed tomography, including superior accuracy and lower radiation exposure. It provides powerful prognostic information, which can help to stratify patients and guide clinicians. The addition of flow quantification enables better detection of multivessel disease while providing incremental prognostic information. Flow quantification provides important physiologic information, which may be useful to individualize patient therapy. This approach is being applied in some centers, but requires standardization before it is more widely applied.
authors.affiliation: Division of Cardiology, Department of Medicine, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada.
authors.forename: Daniel
authors.initials: D
authors.lastname: Juneau
authors.affiliation: Division of Cardiology, Department of Medicine, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada.
authors.forename: Fernanda
authors.initials: F
authors.lastname: Erthal
authors.affiliation: Division of Cardiology, Department of Medicine, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada; First Department of Medicine, Hokkaido University Graduate School of Medicine, Kita 15 Nishi 7, Kita-Ku, Sapporo, Hokkaido 060-8638, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ohira
authors.affiliation: Division of Cardiology, Department of Medicine, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada.
authors.forename: Brian
authors.initials: B
authors.lastname: Mc Ardle
authors.affiliation: Division of Cardiology, Department of Medicine, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada.
authors.forename: Renée
authors.initials: R
authors.lastname: Hessian
authors.affiliation: Division of Cardiology, Department of Medicine, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada.
authors.forename: Robert A
authors.initials: RA
authors.lastname: deKemp
authors.affiliation: Division of Cardiology, Department of Medicine, National Cardiac PET Centre, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario K1Y 4W7, Canada. Electronic address: rbeanlands@ottawaheart.ca.
authors.forename: Rob S B
authors.initials: RS
authors.lastname: Beanlands
mesh_terms: D000066491:Clinical Decision-Making; D003324:Coronary Artery Disease / Q000175:diagnosis*; D003326:Coronary Circulation; D006801:Humans; D064847:Multimodal Imaging; D055414:Myocardial Perfusion Imaging; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals
keywords: Flow quantification; Myocardial blood flow; Myocardial flow reserve; Myocardial perfusion imaging; N-13-ammonia; PET; Rubidium-82