title: A fatal complication after repair of post-infarction ventricular septal rupture: heparin-induced thrombocytopenia with thrombosis.
abstract: Heparin-induced thrombocytopenia (HIT) is a rare but potentially devastating and life-threatening complication from using heparin. HIT not only causes thrombocytopenia, but it also carries an increased risk for fatal thrombotic complications. In this report, we describe the case of a patient in whom fatal HIT developed after successful surgical repair of a posterior post-infarction ventricular septal rupture with cardiopulmonary bypass.
authors.affiliation: Department of Cardiovascular Surgery, Faculty of Medicine, University of Turgut Ozal, Ankara, Turkey.
authors.forename: Yunus
authors.initials: Y
authors.lastname: Nazli
authors.affiliation: Department of Cardiovascular Surgery, Faculty of Medicine, University of Turgut Ozal, Ankara, Turkey.
authors.forename: Necmettin
authors.initials: N
authors.lastname: Colak
authors.affiliation: Department of Cardiology, Faculty of Medicine, University of Turgut Ozal, Ankara, Turkey.
authors.forename: Bora
authors.initials: B
authors.lastname: Demircelik
authors.affiliation: Department of Cardiovascular Surgery, Faculty of Medicine, University of Turgut Ozal, Ankara, Turkey.
authors.forename: Mehmet Faith
authors.initials: MF
authors.lastname: Alpay
authors.affiliation: Department of Cardiovascular Surgery, Faculty of Medicine, University of Turgut Ozal, Ankara, Turkey.
authors.forename: Omer
authors.initials: O
authors.lastname: Cakir
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey.
authors.forename: Kerim
authors.initials: K
authors.lastname: Cagli
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D017809:Fatal Outcome; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D013536:Suture Techniques; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000175:diagnosis; D013927:Thrombosis / Q000139:chemically induced* / Q000175:diagnosis; D013997:Time Factors; D016896:Treatment Outcome; D018658:Ventricular Septal Rupture / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*
chemical_list: D000925:Anticoagulants; D006493:Heparin