title: An efficacy and safety comparison between different stentriever designs in acute ischaemic stroke: a systematic review and meta-analysis.
abstract: OBJECTIVE
  To assess the recanalisation rates and long-term functional outcomes of the Solitaire and Trevo devices; to compare these results to those from the Solitaire With the Intention For Thrombectomy (SWIFT) trial and TREVO 2 studies; and to assess for statistical differences in the outcomes between the two devices.
  
  
  METHODS
  A systematic review and meta-analysis of studies that utilised stentrievers in the treatment of acute ischaemic stroke was conducted. The results were compared to those of the SWIFT and TREVO 2 trials and outcome differences between Trevo (Stryker, Kalamazoo, Michigan, USA) and Solitaire (ev3/Covidien, Irvine, California, USA) were analysed statistically.
  
  
  RESULTS
  Solitaire had a lower mortality rate compared to Trevo (16.2% [95% confidence interval {CI}: 13.1%, 19.8%] versus 22.2% [95% CI: 10.8%, 40.2%]) and achieved a higher rate of functional independence (52.1% [95% CI: 46.3%, 57.8%] versus 47.6% [95% CI: 36.7%, 58.8%]). Statistical tests, however, failed to demonstrate significant differences in either functional outcomes or 3-month mortality rates. No significant differences were noted in weighted mean recanalisation rates between the Solitaire and Trevo groups.
  
  
  CONCLUSIONS
  Stentrievers achieve a high rate of recanalisation and functional independence in acute ischaemic stroke and have a relatively good safety profile. No significant differences in functional outcomes, mortality, and symptomatic intra-cranial haemorrhage could be demonstrated between two popular stentrievers designs, namely Trevo and Solitaire.
authors.affiliation: Medical Imaging Department, Mater Dei Hospital, Malta. Electronic address: reubengrech@yahoo.com.
authors.forename: R
authors.initials: R
authors.lastname: Grech
authors.affiliation: Medical Imaging Department, Mater Dei Hospital, Malta.
authors.forename: R
authors.initials: R
authors.lastname: Pullicino
authors.affiliation: Department of Neuroradiology, Beaumont Hospital, Dublin, Ireland.
authors.forename: J
authors.initials: J
authors.lastname: Thornton
authors.affiliation: Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.
authors.forename: J
authors.initials: J
authors.lastname: Downer
mesh_terms: D002545:Brain Ischemia / Q000601:surgery*; D020878:Device Removal / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D061185:Mechanical Thrombolysis / Q000295:instrumentation*; D015607:Stents; D020521:Stroke / Q000601:surgery*