title: [PHARMACOLOGICAL NEUROPROTECTION IN CARDIOSURGERY (Part 1): DRUGS FOR GENERAL ANESTHESIA].
abstract: This literature review is devoted to modern condition of pharmacological neuroprotection. Aeuroprotection as a complex method of brain protection and reduction of neurological complications is a relevant trend in practical anesthesia and intensive care. The following data represents frequency of neurological complications in different types of surgery and its main classifications. In the first part of the review potential neuroprotectional abilities of modern anesthesia medications are discussed Mechanisms of neuronal destruction and possible ways of impact on the pathophysiological processes via pharmacological agents are observed. The most promising drugs with neuroprotectional effects are selected. In the second part of the review we are going to examine neuroprotection effects of non-anesthetic drugs.
authors.forename: T V
authors.initials: TV
authors.lastname: Klipa
authors.forename: A A
authors.initials: AA
authors.lastname: Eremenko
authors.forename: A N
authors.initials: AN
authors.lastname: Shepelyuk
authors.forename: I O
authors.initials: IO
authors.lastname: Antonov
mesh_terms: D018681:Anesthetics, General / Q000008:administration & dosage / Q000627:therapeutic use; D001921:Brain / Q000098:blood supply / Q000187:drug effects / Q000503:physiopathology; D001927:Brain Diseases / Q000209:etiology / Q000517:prevention & control*; D002318:Cardiovascular Diseases / Q000503:physiopathology / Q000601:surgery*; D013504:Cardiovascular Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D006801:Humans
chemical_list: D018681:Anesthetics, General