title: Performance of the Cryptococcal Antigen Lateral Flow Assay in Non-HIV-Related Cryptococcosis.
abstract: The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.
authors.affiliation: Microbiology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Anupop
authors.initials: A
authors.lastname: Jitmuang
authors.affiliation: National Institute of Allergy and Infectious Diseases, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Anil A
authors.initials: AA
authors.lastname: Panackal
authors.affiliation: National Institute of Allergy and Infectious Diseases, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Peter R
authors.initials: PR
authors.lastname: Williamson
authors.affiliation: National Institute of Allergy and Infectious Diseases, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: John E
authors.initials: JE
authors.lastname: Bennett
authors.affiliation: Microbiology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: John P
authors.initials: JP
authors.lastname: Dekker
authors.affiliation: Microbiology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA azelazny@cc.nih.gov.
authors.forename: Adrian M
authors.initials: AM
authors.lastname: Zelazny
mesh_terms: D000328:Adult; D000946:Antigens, Fungal / Q000276:immunology*; D003453:Cryptococcosis / Q000175:diagnosis* / Q000382:microbiology*; D003454:Cryptococcus / Q000276:immunology*; D005260:Female; D006801:Humans; D007159:Immunologic Tests / Q000379:methods / Q000592:standards; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D000946:Antigens, Fungal