title: Chemical composition and evaluation of the antimicrobial activity of the essential oil from leaves of Eugenia platysema.
abstract: This study describes the qualitative and quantitative chemical composition and evaluates the antibacterial activity of essential oil from Eugenia platysema leaves. Analysis by GC-FID and GC-MS allowed the identification of 22 compounds. Different from the other species of the Eugenia genus, the major compound found in the essential oil was the diterpene phytol (66.05%), being this the first report of the presence of this compound in the essential oils from Eugenia genus. The sesquiterpene elixene was the second most concentrated compound in the studied essential oil (9.16%). The essential oil from E. platysema was tested for its antibacterial activity against cell-walled bacteria and mollicute strains of clinical interest using the microdilution broth assay. The results showed that the essential oil of E. platysema was inactive until 1000 μg mL(-1) against tested bacteria.
authors.affiliation: a Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Adrielli
authors.initials: A
authors.lastname: Tenfen
authors.affiliation: a Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Diogo Alexandre
authors.initials: DA
authors.lastname: Siebert
authors.affiliation: a Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Celina Noriko
authors.initials: CN
authors.lastname: Yamanaka
authors.affiliation: a Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Caio Maurício
authors.initials: CM
authors.lastname: Mendes de Córdova
authors.affiliation: b Instituto de Pesquisas Tecnológicas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Dilamara Riva
authors.initials: DR
authors.lastname: Scharf
authors.affiliation: b Instituto de Pesquisas Tecnológicas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Edésio Luiz
authors.initials: EL
authors.lastname: Simionatto
authors.affiliation: a Departamento de Ciências Farmacêuticas , Universidade Regional de Blumenau , Blumenau , Brazil.
authors.forename: Michele Debiasi
authors.initials: MD
authors.lastname: Alberton
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification; D000890:Anti-Infective Agents / Q000032:analysis / Q000737:chemistry* / Q000302:isolation & purification; D000068856:Eugenia / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000627:therapeutic use; D010836:Phytol / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D009822:Oils, Volatile; D012717:Sesquiterpenes; D010836:Phytol
keywords: Eugenia platysema; antibacterial activity; essential oil; phytol