title: [Examination of Visual Effect in Low-dose Cerebral CT Perfusion Phantom Image Using Iterative Reconstruction].
abstract: CT perfusion (CTP) is obtained cerebrovascular circulation image for assessment of stroke patients; however, at the expense of increased radiation dose by dynamic scan. Iterative reconstruction (IR) method is possible to decrease image noise, it has the potential to reduce radiation dose. The purpose of this study is to assess the visual effect of IR method by using a digital perfusion phantom. The digital perfusion phantom was created by reconstructed filtered back projection (FBP) method and IR method CT images that had five exposure doses. Various exposure dose cerebral blood flow (CBF) images were derived from deconvolution algorithm. Contrast-to-noise ratio (CNR) and visual assessment were compared among the various exposure dose and each reconstructions. Result of low exposure dose with IR method showed, compared with FBP method, high CNR in severe ischemic area, and visual assessment was significantly improvement. IR method is useful for improving image quality of low-dose CTP.
authors.affiliation: Department of Radiology, Research Institute for Brain and Blood Vessels-Akita.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Ohmura
authors.forename: Yongbum
authors.initials: Y
authors.lastname: Lee
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Takahashi
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Sato
authors.forename: Takato
authors.initials: T
authors.lastname: Ishida
authors.forename: Hideto
authors.initials: H
authors.lastname: Toyoshima
mesh_terms: D001921:Brain / Q000098:blood supply*; D002560:Cerebrovascular Circulation; D003287:Contrast Media; D006801:Humans; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D059629:Signal-To-Noise Ratio; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*
chemical_list: D003287:Contrast Media