title: Profiling of lipid and glycogen accumulations under different growth conditions in the sulfothermophilic red alga Galdieria sulphuraria.
abstract: The unicellular red alga Galdieria sulphuraria grows efficiently and produces a large amount of biomass in acidic conditions at high temperatures. It has great potential to produce biofuels and other beneficial compounds without becoming contaminated with other organisms. In G. sulphuraria, biomass measurements and glycogen and lipid analyses demonstrated that the amounts and compositions of glycogen and lipids differed when cells were grown under autotrophic, mixotrophic, and heterotrophic conditions. Maximum biomass production was obtained in the mixotrophic culture. High amounts of glycogen were obtained in the mixotrophic cultures, while the amounts of neutral lipids were similar between mixotrophic and heterotrophic cultures. The amounts of neutral lipids were highest in red algae, including thermophiles. Glycogen structure and fatty acids compositions largely depended on the growth conditions.
authors.affiliation: School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Sakurai
authors.affiliation: School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Motohide
authors.initials: M
authors.lastname: Aoki
authors.affiliation: Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaragi 305-8572, Japan.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Ju
authors.affiliation: School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Ueda
authors.affiliation: Faculty of Bioresource Sciences, Akita Prefectural University, Akita 010-0195, Japan.
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Nakamura
authors.affiliation: School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Shoko
authors.initials: S
authors.lastname: Fujiwara
authors.affiliation: School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Tomonari
authors.initials: T
authors.lastname: Umemura
authors.affiliation: School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan; Japan Science and Technology Agency, CREST, 5 Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan.
authors.forename: Mikio
authors.initials: M
authors.lastname: Tsuzuki
authors.affiliation: Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaragi 305-8572, Japan. Electronic address: minoda.ayumi.gb@u.tsukuba.ac.jp.
authors.forename: Ayumi
authors.initials: A
authors.lastname: Minoda
mesh_terms: D018533:Biomass; D005227:Fatty Acids / Q000378:metabolism; D006003:Glycogen / Q000737:chemistry / Q000378:metabolism*; D008055:Lipids / Q000096:biosynthesis*; D000461:Rhodophyta / Q000254:growth & development* / Q000378:metabolism*; D013455:Sulfur / Q000378:metabolism*; D013696:Temperature
chemical_list: D005227:Fatty Acids; D008055:Lipids; D013455:Sulfur; D006003:Glycogen
keywords: Biomass; Galdieria sulphuraria; Glycogen; Lipid; Red algae