title: A New Terminal Cyano Group-containing Benzodiazepine Alkaloid from the Mangrove Endophytic Fungus Penicillium sp. .
abstract: A new benzodiazepine alkaloid containing terminal cyano group has been isolated from a mangrove endophytic fungus, Penicillium 299#. Structure elucidation was determined by 1D and 2D NMR spectroscopy and the absolute configuration was determined by electronic circular dichroism (ECD). The new compound showed no cytotoxic activities in vitro against human cancer lines MDA-MB-435, HepG2, HCT-116, and Calu-3.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Yi-sheng
authors.initials: YS
authors.lastname: Zhong
authors.forename: Jie
authors.initials: J
authors.lastname: Yuan
authors.forename: Xun
authors.initials: X
authors.lastname: Zhu
authors.forename: Yong-jun
authors.initials: YJ
authors.lastname: Lu
authors.forename: Yong-cheng
authors.initials: YC
authors.lastname: Lin
authors.forename: Lan
authors.initials: L
authors.lastname: Liu
mesh_terms: D027901:Acanthaceae / Q000382:microbiology*; D000470:Alkaloids / Q000737:chemistry*; D001569:Benzodiazepines / Q000737:chemistry*; D010407:Penicillium / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D001569:Benzodiazepines