title: Immobilization of Metal-Organic Framework Copper(II) Benzene-1,3,5-tricarboxylate (CuBTC) onto Cotton Fabric as a Nitric Oxide Release Catalyst.
abstract: Immobilization of metal-organic frameworks (MOFs) onto flexible polymeric substrates as secondary supports expands the versatility of MOFs for surface coatings for the development of functional materials. In this work, we demonstrate the deposition of copper(II) benzene-1,3,5-tricarboxylate (CuBTC) crystals directly onto the surface of carboxyl-functionalized cotton capable of generating the therapeutic bioagent nitric oxide (NO) from endogenous sources. Characterization of the CuBTC-cotton material by XRD, ATR-IR, and UV-vis indicate that CuBTC is successfully immobilized on the cotton fabric. In addition, SEM imaging reveals excellent surface coverage with well-defined CuBTC crystals. Subsequently, the CuBTC-cotton material was evaluated as a supported heterogeneous catalyst for the generation of NO using S-nitrosocysteamine as the substrate. The resulting reactivity is consistent with the activity observed for unsupported CuBTC particles. Overall, this work demonstrates deposition of MOFs onto a flexible polymeric material with excellent coverage as well as catalytic NO release from S-nitrosocysteamine at therapeutic levels.
authors.affiliation: Department of Chemistry, Colorado State University , Fort Collins, Colorado 80523, United States.
authors.forename: Megan J
authors.initials: MJ
authors.lastname: Neufeld
authors.affiliation: Chemical and Biological Engineering, Colorado School of Mines , Golden, Colorado 80401, United States.
authors.forename: Jacqueline L
authors.initials: JL
authors.lastname: Harding
authors.affiliation: Department of Chemistry, Colorado State University , Fort Collins, Colorado 80523, United States.|School of Biomedical Engineering, Colorado State University , Fort Collins, Colorado 80523, United States.
authors.forename: Melissa M
authors.initials: MM
authors.lastname: Reynolds
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D032561:Cotton Fiber; D008745:Methylation; D009569:Nitric Oxide / Q000737:chemistry*; D013057:Spectrum Analysis; D014233:Tricarboxylic Acids / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D014233:Tricarboxylic Acids; D009569:Nitric Oxide; D003300:Copper; C069849:trimesic acid
keywords: catalysis; cotton; hard−soft interfaces; metal−organic frameworks; nitric oxide