title: Unique Medicinal Properties of Withania somnifera: Phytochemical Constituents and Protein Component.
abstract: Withania somnifera is an important medicinal herb that has been widely used for the treatment of different clinical conditions. The overall medicinal properties of Withania somnifera make it a viable therapeutic agent for addressing anxiety, cancer, microbial infection, immunomodulation, and neurodegenerative disorders. Biochemical constituents of Withania somnifera like withanolideA, withanolide D, withaferin A and withaniamides play an important role in its pharmacological properties. Proteins like Withania somnifera glycoprotein and withania lectin like-protein possess potent therapeutic properties like antimicrobial, anti-snake venom poison and antimicrobial. In this review, we have tried to present different pharmacological properties associated with different extract preparations, phytochemical constituents and protein component of Withania somnifera. Future insights in this direction have also been highlighted.
authors.forename: Parvaiz A
authors.initials: PA
authors.lastname: Dar
authors.forename: Laishram R
authors.initials: LR
authors.lastname: Singh
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Kamal
authors.affiliation: Clinical Biochemistry, University of Kashmir, Hazratbal, Srinagar, Jammu and Kashmir. tanveerali@kashmiruniversity.ac.in.
authors.forename: Tanveer A
authors.initials: TA
authors.lastname: Dar
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001007:Anxiety / Q000188:drug therapy; D006801:Humans; D056747:Immunomodulation / Q000187:drug effects; D009369:Neoplasms / Q000188:drug therapy; D019636:Neurodegenerative Diseases / Q000188:drug therapy; D064209:Phytochemicals / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use*; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D010940:Plant Proteins / Q000302:isolation & purification / Q000378:metabolism*; D032341:Withania / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D064209:Phytochemicals; D010936:Plant Extracts; D010940:Plant Proteins