title: Elevated transpulmonary gradient and cardiac magnetic resonance-derived right ventricular remodeling predict poor outcomes in sickle cell disease.
authors.affiliation: Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA Division of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles Healthcare System, CA, USA.
authors.forename: Kim-Lien
authors.initials: KL
authors.lastname: Nguyen
authors.affiliation: Office of Biostatistics Research, National Heart, Lung and Blood Institute, Bethesda, MD, USA.
authors.forename: Xin
authors.initials: X
authors.lastname: Tian
authors.affiliation: Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA.
authors.forename: Shoaib
authors.initials: S
authors.lastname: Alam
authors.affiliation: Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA Howard University College of Medicine, Washington, DC, USA.
authors.forename: Alem
authors.initials: A
authors.lastname: Mehari
authors.affiliation: Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA Division of Cardiovascular Medicine, University of Kentucky, Lexington, KY, USA.
authors.forename: Steve W
authors.initials: SW
authors.lastname: Leung
authors.affiliation: Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA.
authors.forename: Catherine
authors.initials: C
authors.lastname: Seamon
authors.affiliation: Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA.
authors.forename: Darlene
authors.initials: D
authors.lastname: Allen
authors.affiliation: Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA Division of Hematology/Oncology, Sickle Cell Center, Montefiore Medical Center, New York, NY, USA.
authors.forename: Caterina P
authors.initials: CP
authors.lastname: Minniti
authors.affiliation: Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA.
authors.forename: Vandana
authors.initials: V
authors.lastname: Sachdev
authors.affiliation: Cardiovascular and Pulmonary Branch, Lung and Blood Institute, Bethesda, MD, USA.
authors.forename: Andrew E
authors.initials: AE
authors.lastname: Arai
authors.affiliation: Sickle Cell Vascular Disease Section, Hematology Branch, Lung and Blood Institute, Bethesda, MD, USA Division of Hematology/Oncology and Adult Sickle Cell Center of Excellence, University of Pittsburgh, PA, USA katogj@upmc.edu.
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Kato
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D006328:Cardiac Catheterization; D002302:Cardiac Output; D002306:Cardiac Volume; D005260:Female; D006339:Heart Rate; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis; D014655:Vascular Resistance; D016278:Ventricular Function, Right; D020257:Ventricular Remodeling
keywords: cardiomyopathy; magnetic resonance imaging; pulmonary hypertension; right ventricle; sickle cell disease