title: Nanotechnology based anti-infectives to fight microbial intrusions.
abstract: With the rise in human population across the globe especially in developing countries, the incidence of microbial infections are increasing with greater pace. On the other hand, available medication and therapies are found to be insufficient for the complete cure of such microbial infections due to the development of resistance against various antibiotics. Therefore, to cope up the menace of microbial infections and drug resistance, there is demand for new and compelling technology, which has the ability to impede these problems. Many research groups worldwide are finding a ray of hope in nanomaterials owing to their unique properties. In the present review we have discussed the reasons behind the development of new materials based on nanotechnology. It is mainly focused on pioneering studies on application of nanomaterials like carbon nanotube, fullerene, dendrimers, nanocomposite and metal nanoparticles in combating dreadful pathogens. Moreover, the concerns about their toxicity have also been discussed.
authors.affiliation: Nanobiotechnology Laboratory, Department of Biotechnology, S.G.B. Amravati University, Amravati, Maharashtra, India.
authors.forename: M
authors.initials: M
authors.lastname: Rai
authors.affiliation: Nanobiotechnology Laboratory, Department of Biotechnology, S.G.B. Amravati University, Amravati, Maharashtra, India.
authors.forename: A P
authors.initials: AP
authors.lastname: Ingle
authors.affiliation: Nanobiotechnology Laboratory, Department of Biotechnology, S.G.B. Amravati University, Amravati, Maharashtra, India.|Department of Biotechnology, Engineering School of Lorena, Estrada municipal do Campinho, University of Sao Paulo, Lorena, SP, Brazil.
authors.forename: S
authors.initials: S
authors.lastname: Gaikwad
authors.affiliation: Nanobiotechnology Laboratory, Department of Biotechnology, S.G.B. Amravati University, Amravati, Maharashtra, India.|Department of Biotechnology, Institute of Science, Aurangabad, Maharashtra, India.
authors.forename: I
authors.initials: I
authors.lastname: Gupta
authors.affiliation: Nanobiotechnology Laboratory, Department of Biotechnology, S.G.B. Amravati University, Amravati, Maharashtra, India.
authors.forename: A
authors.initials: A
authors.lastname: Gade
authors.affiliation: Department of Biotechnology, Engineering School of Lorena, Estrada municipal do Campinho, University of Sao Paulo, Lorena, SP, Brazil.
authors.forename: S
authors.initials: S
authors.lastname: Silvério da Silva
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D049329:Nanostructures / Q000627:therapeutic use* / Q000633:toxicity; D036103:Nanotechnology
chemical_list: D000900:Anti-Bacterial Agents
keywords: antimicrobial activity; carbon nanotube; dendrimers; fullerene; metal nanoparticles; nanocomposite; nanotoxicity