title: Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signaling.
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane School of Medicine, University of Queensland.
authors.forename: Therese
authors.initials: T
authors.lastname: Vu
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane School of Medicine, University of Queensland.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Austin
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane.
authors.forename: Catherine Paine
authors.initials: CP
authors.lastname: Kuhn
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane.
authors.forename: Claudia
authors.initials: C
authors.lastname: Bruedigam
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane.
authors.forename: Axia
authors.initials: A
authors.lastname: Song
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane.
authors.forename: Solene
authors.initials: S
authors.lastname: Guignes
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane.
authors.forename: Sebastien
authors.initials: S
authors.lastname: Jacquelin
authors.affiliation: Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide.
authors.forename: Hayley S
authors.initials: HS
authors.lastname: Ramshaw
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane Cancer Care Services, Royal Brisbane and Women's Hospital, Brisbane, Australia.
authors.forename: Geoffrey R
authors.initials: GR
authors.lastname: Hill
authors.affiliation: Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide.
authors.forename: Angel F
authors.initials: AF
authors.lastname: Lopez
authors.affiliation: Division of Immunology, QIMR Berghofer Medical Research Institute, Brisbane School of Medicine, University of Queensland Cancer Care Services, Royal Brisbane and Women's Hospital, Brisbane, Australia Steven.lane@qimrberghofer.edu.au.
authors.forename: Steven W
authors.initials: SW
authors.lastname: Lane
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000276:immunology / Q000473:pathology; D015972:Gene Expression Regulation, Neoplastic; D019337:Hematologic Neoplasms / Q000235:genetics / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007377:Interleukin-3 / Q000235:genetics / Q000276:immunology*; D053614:Janus Kinase 2 / Q000235:genetics / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008822:Mice, Transgenic; D009154:Mutation; D009196:Myeloproliferative Disorders / Q000235:genetics / Q000276:immunology* / Q000473:pathology; D016185:Receptors, Interleukin-3 / Q000235:genetics / Q000276:immunology*; D050799:STAT5 Transcription Factor / Q000235:genetics / Q000276:immunology; D015398:Signal Transduction; D013926:Thrombopoietin / Q000494:pharmacology
chemical_list: D007377:Interleukin-3; D016185:Receptors, Interleukin-3; D050799:STAT5 Transcription Factor; D013926:Thrombopoietin; C507926:Jak2 protein, mouse; D053614:Janus Kinase 2
keywords: chronic myeloproliferative disorders; cytokine signaling; hematopoietic stem cell