title: A study of mastoid pneumatisation and the presence of cholesteatoma in 393 patients.
abstract: OBJECTIVE
  This study aimed to evaluate the relationship between cholesteatoma formation and the degree of mastoid pneumatisation, and to assess the relationship between the location of cholesteatoma and the degree of mastoid pneumatisation.
  
  
  METHODS
  Data on all patients undergoing mastoid exploration for cholesteatoma between 1993 and 2011 were collected prospectively. Basic demographics, the degree of mastoid pneumatisation and cholesteatoma site were recorded.
  
  
  RESULTS
  A total of 393 patients (222 males and 171 females) underwent surgery for cholesteatoma. Patients' mean age was 37 years (range, 6-79 years). Pneumatisation of the mastoid was sclerotic in 23 per cent (n = 90), diploic in 16.7 per cent (n = 66) and cellular in 60.3 per cent of cases (n = 237) (p < 0.001). Atticoantral disease was present in 88.9 per cent of sclerotic, 95.4 per cent of diploic and 91.1 per cent of cellular mastoids. Middle-ear cholesteatoma was present in 54.4 per cent of sclerotic, 56 per cent of diploic and 51.9 per cent of cellular mastoids.
  
  
  CONCLUSIONS
  The findings demonstrate the presence of cholesteatoma in well-pneumatised mastoids. It is hypothesised that a well-pneumatised mastoid may lead to cholesteatoma formation.
authors.affiliation: Department of Otolaryngology,Northern Deanery,Newcastle upon Tyne,UK.
authors.forename: I Z
authors.initials: IZ
authors.lastname: Iqbal
authors.affiliation: Department of Otolaryngology,Darlington Memorial Hospital,UK.
authors.forename: C
authors.initials: C
authors.lastname: Watson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000388:Air; D001847:Bone Diseases / Q000150:complications*; D002648:Child; D018424:Cholesteatoma, Middle Ear / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008416:Mastoid / Q000473:pathology*; D008875:Middle Aged; D011446:Prospective Studies; D012598:Sclerosis / Q000150:complications; D055815:Young Adult
keywords: Cholesteatoma; Mastoid; Middle Ear