title: Hypoglycemic episodes in a case of Prementrual Dysphoric Disorder on sertraline.
abstract: Sertraline is a selective serotonin reuptake inhibitor. It has been shown to blunt postprandial hyperglycemia in rats and to potentiate the hypoglycemic effects of sulfonylurea agents in humans. Here, we report a case of a 33-year-old nondiabetic patient with no history of glucose intolerance, who experienced multiple episodes of hypoglycemia that resolved after discontinuation of the drug. Healthcare professionals should consider sertraline among the possible causes of hypoglycemia occurring in patients receiving antidepressants.
authors.affiliation: Department of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, West Bengal, India.
authors.forename: Ranjita
authors.initials: R
authors.lastname: Santra Dhali
authors.affiliation: Department of Pharmacology, Sagar Dutta Medical College, Kolkata, West Bengal, India.
authors.forename: Prithwijit
authors.initials: P
authors.lastname: Banerjee
authors.affiliation: Department of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, West Bengal, India.
authors.forename: Santanu
authors.initials: S
authors.lastname: Munshi
authors.affiliation: Department of Pharmacology, Calcutta National Medical College, Kolkata, West Bengal, India.
authors.forename: Patralekha Ray
authors.initials: PR
authors.lastname: Chaudhuri
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced*; D065446:Premenstrual Dysphoric Disorder / Q000188:drug therapy*; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D020280:Sertraline / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline
keywords: Drug-induced hypoglycemia; selective serotonin reuptake inhibitors; sertraline