title: Myopia Control with a Novel Peripheral Gradient Soft Lens and Orthokeratology: A 2-Year Clinical Trial.
abstract: OBJECTIVE
  To evaluate the degree of axial elongation with soft radial refractive gradient (SRRG) contact lenses, orthokeratology (OK), and single vision (SV) spectacle lenses (control) during a period of 1 year before treatment and 2 years after treatment.
  
  
  METHODS
  This was a prospective, longitudinal, nonrandomized study. The study groups consisted of 30, 29, and 41 children, respectively. The axial length (AL) was measured during 2 years after recruitment and lens fitting.
  
  
  RESULTS
  The baseline refractive sphere was correlated significantly (Spearman's Rho (ρ) correlation = 0.542; P < 0.0001) with the amount of myopia progression before baseline. After 2 years, the mean myopia progression values for the SRRG, OK, and SV groups were -0.56 ± 0.51, -0.32 ± 0.53, and -0.98 ± 0.58 diopter, respectively. The results represent reductions in myopic progression of 43% and 67% for the SRRG and OK groups, respectively, compared to the SV group. The AL increased 27% and 38% less in the SRRG and OK groups, respectively compared with the SV group at the 2-year visit (P < 0.05). Axial elongation was not significantly different between SRRG and OK (P = 0.430).
  
  
  CONCLUSIONS
  The SRRG lens significantly decreased AL elongation compared to the SV control group. The SRRG lens was similarly effective to OK in preventing myopia progression in myopic children and adolescent.
authors.affiliation: Centro Médico Teknon, 08022 Barcelona, Spain.
authors.forename: Jaime
authors.initials: J
authors.lastname: Pauné
authors.affiliation: Centro Médico Teknon, 08022 Barcelona, Spain.
authors.forename: Hari
authors.initials: H
authors.lastname: Morales
authors.affiliation: Departament d'Òptica i Optometria, Universitat Politècnica de Catalunya-BarcelonaTech (UPC), 08222 Terrassa, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Armengol
authors.affiliation: Departament d'Òptica i Optometria, Universitat Politècnica de Catalunya-BarcelonaTech (UPC), 08222 Terrassa, Spain.
authors.forename: Lluisa
authors.initials: L
authors.lastname: Quevedo
authors.affiliation: Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics, University of Minho, 4710-057 Braga, Portugal.
authors.forename: Miguel
authors.initials: M
authors.lastname: Faria-Ribeiro
authors.affiliation: Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics, University of Minho, 4710-057 Braga, Portugal.
authors.forename: José M
authors.initials: JM
authors.lastname: González-Méijome
mesh_terms: D000293:Adolescent; D002648:Child; D003263:Contact Lenses, Hydrophilic; D005260:Female; D006801:Humans; D008297:Male; D009216:Myopia / Q000503:physiopathology* / Q000628:therapy*; D011446:Prospective Studies