title: [INFLUENCE OF AUTOLOGOUS CHONDROCYTES TRANSPLANTATION ON THE INTERVERTEBRAL DISC STATE IN EXPERIMENTAL MODEL OF OSTEOCHONDROSIS].
abstract: The degenerative changes in the nucleus pulposus and fibrous ring of the intervertebral discs are the basis of spinal osteochondrosis. A large number of models, including biological, where some mechanisms of their development were worked out and studied, was used to study the morphogenesis and pathogenesis of degenerative spinal changes. The deserved place in the comparative experiments and especially the different methods of therapeutic effects on the tissues of the intervertebral discs in degenerative spinal changes is taken by the experimental methods. The biochemical changes of the intervertebral disc structures were analyzed under the administration of cultured autologous cell of nucleus pulposus suspension against a background of experimental model of rat osteochondrosis.
authors.forename: M V
authors.initials: MV
authors.lastname: Khyzhnyak
mesh_terms: D053674:Aggrecans / Q000235:genetics / Q000378:metabolism; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D019902:Chondrocytes / Q000166:cytology / Q000378:metabolism / Q000637:transplantation*; D024043:Collagen Type II / Q000235:genetics / Q000378:metabolism; D004195:Disease Models, Animal; D015870:Gene Expression; D006801:Humans; D007403:Intervertebral Disc / Q000378:metabolism / Q000473:pathology*; D055034:Osteochondrosis / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D051381:Rats; D014182:Transplantation, Autologous
chemical_list: C508321:Acan protein, rat; D053674:Aggrecans; D015415:Biomarkers; D024043:Collagen Type II