title: [ACUTE KIDNEY INJURY AND IN-HOSPITAL MORTALITY IN PATIENTS WITH STROKE].
abstract: OBJECTIVE
  to estimate the frequency and severity of acute kidney injury (AKI) in patients with stroke and the influence of AKI on intra-hospital lethality.
  
  
  METHODS
  180 patients with stroke. 8 (4.4%) of them died within 24 hr after admission. It was impossible to diagnose AKI in these patients from serum creatinine dynamics. The development of AKI was followed up in the remaining 80 (47.1%) men and 91 (52.9%) women (mean age 66.6 ± 11.2 yr). AKI was diagnosed and classified as recommended by KDIGO (2012).
  
  
  RESULTS
  AKI was documented in 47 (27.3%) patients including 13 (41.9%) and 34 (24.1%) with hemorrhagic and ischemic stroke respectively. Logistic regressive analysis revealed association of in-hospital lethality with AKI (relative risk 2.5; 95%, CI 1.7-3.8) regardless of sex, age, stroke type, duration of the disease prior to hospitalisation, arterial hypertension, and diabetes.
  
  
  CONCLUSIONS
  stroke is complicated by AKI in every fourth patient; in combination, they significantly increase intra-hospital lethality.
authors.forename: A M
authors.initials: AM
authors.lastname: Gerdt
authors.forename: A M
authors.initials: AM
authors.lastname: Shutov
authors.forename: M V
authors.initials: MV
authors.lastname: Menzorov
authors.forename: V V
authors.initials: VV
authors.lastname: Naydenova
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D000368:Aged; D003404:Creatinine / Q000097:blood; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications / Q000401:mortality
chemical_list: D003404:Creatinine