title: Titanium-Nitride Coating of Orthopaedic Implants: A Review of the Literature.
abstract: Surfaces of medical implants can be enhanced with the favorable properties of titanium-nitride (TiN). In a review of English medical literature, the effects of TiN-coating on orthopaedic implant material in preclinical studies were identified and the influence of these effects on the clinical outcome of TiN-coated orthopaedic implants was explored. The TiN-coating has a positive effect on the biocompatibility and tribological properties of implant surfaces; however, there are several reports of third body wear due to delamination, increased ultrahigh molecular weight polyethylene wear, and cohesive failure of the TiN-coating. This might be due to the coating process. The TiN-coating process should be optimized and standardized for titanium alloy articulating surfaces. The clinical benefit of TiN-coating of CoCrMo knee implant surfaces should be further investigated.
authors.affiliation: Department of Orthopaedics, Catharina Hospital, 5623 EJ Eindhoven, Netherlands.
authors.forename: Ruud P
authors.initials: RP
authors.lastname: van Hove
authors.affiliation: Research Centre Linnaeus Institute, Spaarne Hospital, 2134 TM Hoofddorp, Netherlands.
authors.forename: Inger N
authors.initials: IN
authors.lastname: Sierevelt
authors.affiliation: Department of Orthopaedics, VU University Medical Centre, 1081 HZ Amsterdam, Netherlands.
authors.forename: Barend J
authors.initials: BJ
authors.lastname: van Royen
authors.affiliation: Research Centre Linnaeus Institute, Spaarne Hospital, 2134 TM Hoofddorp, Netherlands ; Department of Orthopaedics, Spaarne Hospital, 2134 TM Hoofddorp, Netherlands.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Nolte
mesh_terms: D000497:Alloys / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000737:chemistry* / Q000627:therapeutic use; D006801:Humans; D007720:Knee Prosthesis; D009985:Orthopedics; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry* / Q000627:therapeutic use; D014800:Vitallium / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D000497:Alloys; D020099:Coated Materials, Biocompatible; D014800:Vitallium; C041500:titanium nitride; D014025:Titanium