title: Differential Opioid Tolerance and Opioid-induced Hyperalgesia: A Clinical Reality.
authors.affiliation: From the Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee (C.J.H.); and Departments of Anesthesiology and Neurological Surgery, University of Virginia, Charlottesville, Virginia (M.E.D.).
authors.forename: Christina J
authors.initials: CJ
authors.lastname: Hayhurst
authors.forename: Marcel E
authors.initials: ME
authors.lastname: Durieux
mesh_terms: D000701:Analgesics, Opioid / Q000009:adverse effects*; D004361:Drug Tolerance / Q000502:physiology*; D006801:Humans; D006930:Hyperalgesia / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D000701:Analgesics, Opioid