title: Spontaneous exudative retinal detachment in a patient with sturge-weber syndrome after taking arginine, a supplement for erectile dysfunction.
abstract: BACKGROUND
  Patients with Sturge-Weber syndrome can have ipsilateral diffuse or circumscribed choroidal hemangiomas. These hemangiomas have been seen to undergo spontaneous exudative or hemorrhagic retinal detachments. There is no definitive treatment for these types of retinal detachments, but radiotherapy, photodynamic therapy, oral propranolol, pegaptinib and bevacizumab have been used.
  
  
  METHODS
  A 26-year-old male with Sturge-Weber Syndrome developed an exudative retinal detachment that occurred immediately after taking a supplement containing arginine. The patient was treated with intravitreal bevacizumab 1.25 mg in 0.05 ml solution. Resolution of the retinal detachment was seen after 4 treatments over a six-month period.
  
  
  CONCLUSIONS
  Arginine and other medications that cause a release of nitric oxide may lead to intravascular leakage and exudative retinal detachments in patients who have a choroidal hemangioma.
authors.affiliation: Larkin Community Hospital, 7031 SW 62nd Avenue, South Miami, 33143 Florida USA.
authors.forename: Austin
authors.initials: A
authors.lastname: Bach
authors.affiliation: Murray Ocular Oncology & Retina, 6705 Red Road, Suite 412, Miami, 33143 Florida USA.
authors.forename: Aaron S
authors.initials: AS
authors.lastname: Gold
authors.affiliation: Murray Ocular Oncology & Retina, 6705 Red Road, Suite 412, Miami, 33143 Florida USA.
authors.forename: Victor M
authors.initials: VM
authors.lastname: Villegas
authors.affiliation: Murray Ocular Oncology & Retina, 6705 Red Road, Suite 412, Miami, 33143 Florida USA.
authors.forename: Andrea C
authors.initials: AC
authors.lastname: Wildner
authors.affiliation: Murray Ocular Oncology & Retina, 6705 Red Road, Suite 412, Miami, 33143 Florida USA.
authors.forename: Fiona J
authors.initials: FJ
authors.lastname: Ehlies
authors.affiliation: Murray Ocular Oncology & Retina, 6705 Red Road, Suite 412, Miami, 33143 Florida USA.
authors.forename: Timothy G
authors.initials: TG
authors.lastname: Murray
keywords: Choroidal hemangioma; Exudative retinal detachment; Nitric oxide; Sturge-Weber Syndrome; arginine