title: Proof of Concept: Magnetic Fixation of Dendron-Functionalized Iron Oxide Nanoparticles Containing Palladium Nanoparticles for Continuous-Flow Suzuki Coupling Reactions.
abstract: A new concept for the magnetic immobilization of catalytically active material has been developed for continuous-flow Suzuki cross-coupling reactions. The reversible immobilization of the magnetic catalyst material inside a novel capillary microreactor has been achieved by utilizing a newly designed reactor housing with 208 small permanent magnets. As a catalyst material, magnetic Fe3O4 nanoparticles decorated with polyphenylenepyridyl dendrons and loaded with Pd nanoparticles have been employed. Both batch and continuous-flow experiments prove the activity of the catalyst and the applicability of this new microreactor concept.
authors.affiliation: Continuous Chemical Engineering Department, Fraunhofer ICT-IMM , Carl-Zeiss-Straße 18-20, 55129 Mainz, Germany.
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Rehm
authors.affiliation: Continuous Chemical Engineering Department, Fraunhofer ICT-IMM , Carl-Zeiss-Straße 18-20, 55129 Mainz, Germany.
authors.forename: Anca
authors.initials: A
authors.lastname: Bogdan
authors.affiliation: Continuous Chemical Engineering Department, Fraunhofer ICT-IMM , Carl-Zeiss-Straße 18-20, 55129 Mainz, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Hofmann
authors.affiliation: Continuous Chemical Engineering Department, Fraunhofer ICT-IMM , Carl-Zeiss-Straße 18-20, 55129 Mainz, Germany.
authors.forename: Patrick
authors.initials: P
authors.lastname: Löb
authors.affiliation: A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences , 28 Vavilov Street, Moscow 119991, Russia.
authors.forename: Zinaida B
authors.initials: ZB
authors.lastname: Shifrina
authors.affiliation: Department of Chemistry, Indiana University , 800 East Kirkwood Avenue, Bloomington, Indiana 47405, United States.
authors.forename: David G
authors.initials: DG
authors.lastname: Morgan
authors.affiliation: Department of Chemistry, Indiana University , 800 East Kirkwood Avenue, Bloomington, Indiana 47405, United States.|Department of Physics, Faculty of Science, King Abdulaziz University , Jeddah, Saudi Arabia.
authors.forename: Lyudmila M
authors.initials: LM
authors.lastname: Bronstein
keywords: Suzuki coupling; continuous-flow microreactor; dendron; magnetic immobilization; palladium nanoparticles