title: The efficacy of lens removal plus IOL implantation for the treatment of spherophakia with secondary glaucoma.
abstract: OBJECTIVE
  To evaluate the efficacy of lens removal plus intraocular lens (IOL) implantation for spherophakia with secondary glaucoma.
  
  
  METHODS
  A series of 19 patients (n=24 eyes) were split into two groups according to the degree of zonular abnormality as follows: group 1 (within the range of one quadrant, n=7 eyes) and group 2 (beyond the range of one quadrant, n=17 eyes). The patients in group 1 underwent phacoemulsification+capsular tension ring (CTR)+IOL, whereas patients in group 2 underwent pars plana lensectomy with scleral-fixated posterior chamber (PC) IOL implantation. The best corrected visual acuity (BCVA) (logMAR unit) and intraocular pressure (IOP) were documented at presentation and at 1 day, 7 days, 3 months, 1 year and 3 years postoperatively.
  
  
  RESULTS
  The IOP in both groups significantly decreased after surgery (group 1:28.84±5.36 mm Hg at presentation, 15.86±0.79 mm Hg at the 3-year visit, t=6.34, p=0.000; group 2:26.18±12.16 mm Hg at presentation, 14.54±3.40 mm Hg at the 3-year visit, t=3.80, p=0.01). The BCVA increased from 0.79±0.36 at baseline to 0.44±0.38 at the 3-year follow-up but did not reach a significantly different level in group 1 (t=1.72, p=0.11), whereas the BCVA significantly increased from 1.15±0.75 at baseline to 0.43±0.38 at the 3-year visit in group 2 (t=3.45, p=0.02).
  
  
  CONCLUSIONS
  Both phacoemulsification+CTR+IOL and lensectomy with scleral-fixated PC IOL implantation are effective in lowering the IOP and enhancing the visual acuity in patients with spherophakia and secondary glaucoma.
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Fan
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Junyi
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Anjian
authors.initials: A
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Cai
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Sheng
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Wenyi
authors.initials: W
authors.lastname: Lu
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Yongxiang
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai, China Myopia Key Laboratory of Health PR China, Shanghai, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Lu
mesh_terms: D000328:Adult; D002386:Cataract / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007908:Lens, Crystalline / Q000601:surgery*; D008297:Male; D018918:Phacoemulsification / Q000379:methods*; D011446:Prospective Studies; D013997:Time Factors; D014130:Trabeculectomy; D016896:Treatment Outcome; D014792:Visual Acuity
keywords: Glaucoma; Lens and zonules; Treatment Surgery