title: Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma in Older Adults.
abstract: Multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS) are plasma cell disorders of aging. The landscape of the diagnosis and management of MM and MGUS are rapidly changing. This article provides an updated understanding of the clinical presentation, evaluation, diagnosis, and management of older adults with MM and MGUS. Because most oncology providers are not formally trained in geriatric medicine, geriatricians play a key role in providing oncologists with a broader understanding of patient health status in the hope of improving outcomes for older adults with MM.
authors.affiliation: Division of Hematology & Oncology, Department of Medicine, University of North Carolina at Chapel Hill, 170 Manning Drive, Campus Box 7305, Chapel Hill, NC 27599, USA.
authors.forename: Emily J
authors.initials: EJ
authors.lastname: Guerard
authors.affiliation: Division of Cellular Therapy and Hematologic Malignancies, Duke Cancer Institute, DUMC 3961, Durham, NC 27710, USA. Electronic address: sat6@duke.edu.
authors.forename: Sascha A
authors.initials: SA
authors.lastname: Tuchman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D015577:Geriatric Assessment; D006305:Health Status Indicators; D006801:Humans; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000175:diagnosis* / Q000628:therapy*; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000628:therapy*; D012307:Risk Factors
keywords: Cancer; Elderly; Geriatric; MGUS; Multiple myeloma; Neoplasm; Older adult