title: Complication Avoidance in Endoscopic Skull Base Surgery.
abstract: Endoscopic endonasal approaches to the skull base pathology have developed and evolved dramatically over the past 2 decades, particularly with collaboration between neurosurgery and otolaryngology physicians. These advances have increased significantly the use of such approaches beyond just resection of pituitary adenomas, including a variety of skull base pathologies. As the field has evolved, so has our understanding of the complications accompanying endoscopic skull base surgery, as well as techniques to both avoid and manage these complications. These are discussed here.
authors.affiliation: Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, 1500 Holcombe Blvd, Houston, TX 77030, USA.
authors.forename: Peleg M
authors.initials: PM
authors.lastname: Horowitz
authors.affiliation: Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, 1500 Holcombe Blvd, Houston, TX 77030, USA; Department of Neurosurgery, The Mayfield Clinic, University of Cincinnati, 260 Stetson Street, Suite 2200, Cincinnati, OH 45267, USA.
authors.forename: Vincent
authors.initials: V
authors.lastname: DiNapoli
authors.affiliation: Department of Head and Neck Surgery, The University of Texas M.D. Anderson Cancer Center, 1500 Holcombe Blvd, Houston, TX 77030, USA.
authors.forename: Shirley Y
authors.initials: SY
authors.lastname: Su
authors.affiliation: Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, 1500 Holcombe Blvd, Houston, TX 77030, USA; Department of Head and Neck Surgery, The University of Texas M.D. Anderson Cancer Center, 1500 Holcombe Blvd, Houston, TX 77030, USA. Electronic address: smraza@mdanderson.org.
authors.forename: Shaan M
authors.initials: SM
authors.lastname: Raza
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D065634:Cerebrospinal Fluid Leak / Q000517:prevention & control*; D003389:Cranial Nerve Diseases / Q000209:etiology; D004724:Endoscopy / Q000009:adverse effects*; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control*; D008279:Magnetic Resonance Imaging; D008581:Meningitis / Q000517:prevention & control*; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D009666:Nose / Q000601:surgery; D010036:Otolaryngology; D010911:Pituitary Neoplasms / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control*; D011362:Professional Corporations; D019291:Skull Base / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents
keywords: CSF leak; Complications; Cranial nerve injury; Diabetes insipidus; Endoscopic skull base surgery; Panhypopituitarism; Vascular injury