title: Multiple gingival recession coverage with an allogeneic biostatic fascia lata graft using the tunnel technique--A histological assessment.
abstract: BACKGROUND
  Autogenous connective tissue graft (CTG) that can be safely harvested from the palatal mucosa is limited. Often a multi-stage surgical procedure is needed to cover multiple gingival recessions (MGR). To address this problem, efforts are being made to explore substitutes suitable in size to ensure surgical treatment in a single visit.The objective of the present study was the histological evaluation of tissue in the recipient site after augmentation with a hydrated biostatic Fascia Lata Allograft (FLA) in conjunction with MGR coverage at different healing stages.
  
  
  METHODS
  Twelve patients needing bilateral multiple gingival recession coverage participated in this study. On the test side, the tunnel technique with FLA was used, while CTG, harvested from the palatal mucosa, was used to cover MGR on the control side. Histological assessment was performed 3, 6, 9 and 12 months after augmentation.
  
  
  RESULTS
  FLA was well tolerated by the host tissue. During all investigation periods histological images of all patients in the test side revealed a slow process of incorporation of the material grafted in the host connective tissue, showing a colonization of the graft with host fibroblasts and formation of new blood vessels. After 12 months, the graft had fully remodeled into connective tissue of the host gingiva.
  
  
  CONCLUSIONS
  Apart from the limitations of the present study, we conclude that the FLA may serve as a substitute for autogenous CTG harvested from the palatal mucosa and can be applied as a technique for covering MGR in a single visit.
authors.affiliation: Special Medical Practis Stomatologia, Srebrna 48 Street, Pl-42-612 Tarnowskie Góry, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Żurek
authors.affiliation: Dental Surgery Department, Silesian Piast Medical University of Wroclaw, Krakowska 26 Street, Pl-50-425 Wrocław, Poland.
authors.forename: Marzena
authors.initials: M
authors.lastname: Dominiak
authors.affiliation: Special Medical Practice, Pawia 12 Street, Pl-42-612 Tarnowskie Góry, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Tomaszek
authors.affiliation: Department of Orthodontics, Carl Gustav Carus Campus, Technische Universität Dresden, Fetscherstr. 74, D-01309 Dresden, Germany. Electronic address: ute.botzenhart@uniklinikum-dresden.de.
authors.forename: Ute
authors.initials: U
authors.lastname: Botzenhart
authors.affiliation: Dental Surgery Department, Silesian Piast Medical University of Wroclaw, Krakowska 26 Street, Pl-50-425 Wrocław, Poland; Department of Orthodontics, Carl Gustav Carus Campus, Technische Universität Dresden, Fetscherstr. 74, D-01309 Dresden, Germany.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Gedrange
authors.affiliation: Specialistic Outpatient Medical Clinic MEDIDENT, Okulickiego 19 Street, Pl-38-300 Gorlice, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Bednarz
mesh_terms: D000328:Adult; D001706:Biopsy; D003238:Connective Tissue / Q000637:transplantation; D005206:Fascia Lata / Q000637:transplantation*; D005260:Female; D005347:Fibroblasts; D005500:Follow-Up Studies; D005889:Gingival Recession / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000637:transplantation; D010159:Palate; D016896:Treatment Outcome
keywords: Allograft; Connective tissue; Fascia lata; Fibroblasts; Gingival recession