title: Enhanced Bactericidal Activity of Silver Thin Films Deposited via Aerosol-Assisted Chemical Vapor Deposition.
abstract: Silver thin films were deposited on SiO2-barrier-coated float glass, fluorine-doped tin oxide (FTO) glass, Activ glass, and TiO2-coated float glass via AACVD using silver nitrate at 350 °C. The films were annealed at 600 °C and analyzed by X-ray powder diffraction, X-ray photoelectron spectroscopy, UV/vis/near-IR spectroscopy, and scanning electron microscopy. All the films were crystalline, and the silver was present in its elemental form and of nanometer dimension. The antibacterial activity of these samples was tested against Escherichia coli and Staphylococcus aureus in the dark and under UV light (365 nm). All Ag-deposited films reduced the numbers of E. coli by 99.9% within 6 h and the numbers of S. aureus by 99.9% within only 2 h. FTO/Ag reduced bacterial numbers of E. coli to below the detection limit after 60 min and caused a 99.9% reduction of S. aureus within only 15 min of UV irradiation. Activ/Ag reduced the numbers of S. aureus by 66.6% after 60 min and TiO2/Ag killed 99.9% of S. aureus within 60 min of UV exposure. More remarkably, we observed a 99.9% reduction in the numbers of E. coli within 6 h and the numbers of S. aureus within 4 h in the dark using our novel TiO2/Ag system.
authors.affiliation: Materials Chemistry Research Centre, Department of Chemistry, University College London , 20 Gordon Street, London WC1H 0AJ, United Kingdom.
authors.forename: Sapna D
authors.initials: SD
authors.lastname: Ponja
authors.affiliation: Materials Chemistry Research Centre, Department of Chemistry, University College London , 20 Gordon Street, London WC1H 0AJ, United Kingdom.|UCL Division of Surgery and Interventional Science, University College London , 67-73 Riding House Street, London W1 W7EJ, United Kingdom.|Division of Microbial Disease, UCL Eastman Dental Institute, University College London , 256 Gray's Inn Road, London WC1X 8LD, United Kingdom.
authors.forename: Sandeep K
authors.initials: SK
authors.lastname: Sehmi
authors.affiliation: Division of Microbial Disease, UCL Eastman Dental Institute, University College London , 256 Gray's Inn Road, London WC1X 8LD, United Kingdom.
authors.forename: Elaine
authors.initials: E
authors.lastname: Allan
authors.affiliation: UCL Division of Surgery and Interventional Science, University College London , 67-73 Riding House Street, London W1 W7EJ, United Kingdom.
authors.forename: Alexander J
authors.initials: AJ
authors.lastname: MacRobert
authors.affiliation: Materials Chemistry Research Centre, Department of Chemistry, University College London , 20 Gordon Street, London WC1H 0AJ, United Kingdom.
authors.forename: Ivan P
authors.initials: IP
authors.lastname: Parkin
authors.affiliation: Materials Chemistry Research Centre, Department of Chemistry, University College London , 20 Gordon Street, London WC1H 0AJ, United Kingdom.
authors.forename: Claire J
authors.initials: CJ
authors.lastname: Carmalt
mesh_terms: D000336:Aerosols / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D008855:Microscopy, Electron, Scanning; D012834:Silver / Q000737:chemistry / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D014961:X-Ray Diffraction
chemical_list: D000336:Aerosols; D000900:Anti-Bacterial Agents; D012834:Silver
keywords: Ag; CVD; Escherichia coli; FTO; Staphylococcus aureus; antimicrobial