title: Acute liver failure associated with Garcinia cambogia use.
abstract: Millions of Americans regularly use herbal supplements, but many are unaware of the potential hidden dangers. Numerous supplements have been associated with hepatotoxicity and, indeed dietary/herbal supplements represent an increasingly common source of acute liver injury. We report a case of acute liver failure requiring liver transplantation associated with the use of Garcinia cambogia, a supplement widely promoted for weight loss. When patients present with acute hepatitis or liver failure from an unknown etiology, a careful history of supplement use should be performed.
authors.affiliation: Transplantation Center, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Corey
authors.affiliation: Transplantation Center, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: K Tuesday
authors.initials: KT
authors.lastname: Werner
authors.affiliation: Division of Transplantation Surgery, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Singer
authors.affiliation: Division of Transplantation Surgery, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Adyr
authors.initials: A
authors.lastname: Moss
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Maxwell
authors.initials: M
authors.lastname: Smith
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Jessica
authors.initials: J
authors.lastname: Noelting
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Jorge
authors.initials: J
authors.lastname: Rakela
mesh_terms: D019440:Anti-Obesity Agents / Q000009:adverse effects*; D001706:Biopsy; D005260:Female; D029761:Garcinia cambogia / Q000009:adverse effects*; D006801:Humans; D017114:Liver Failure, Acute / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D008111:Liver Function Tests; D016031:Liver Transplantation; D008875:Middle Aged; D008517:Phytotherapy; D028321:Plant Preparations / Q000009:adverse effects*; D010946:Plants, Medicinal; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D019440:Anti-Obesity Agents; D028321:Plant Preparations