title: Surgical resection and chemoradiotherapy for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the oesophagus.
abstract: BACKGROUND
  Basaloid squamous cell carcinoma of the oesophagus (BSCCE) is a relatively rare variant of oesophageal malignancy. There are no established treatment strategies for pulmonary metastases of BSCCE.
  
  
  METHODS
  A 72-year-old man underwent oesophagectomy and subsequently received a pathological diagnosis of stage IIIA (T3N1M0) BSCCE according to Union for International Cancer Control. One year and 5 months later, he underwent partial resection of the right lung because of metastasis of the BSCCE. One year and 6 months after the pulmonary resection, recurrence in the right lung was observed. The patient was treated with concurrent chemoradiotherapy using cisplatin and 5-fluorouracil, and the lesion completely disappeared. The patient is doing well without recurrence 5 years after chemoradiotherapy.
  
  
  CONCLUSIONS
  In our case, the recurrent lesion in the right lung was observed after the pulmonary resection. It is difficult to determine whether the recurrent lesion is solitary or multiple and whether it is a local or pleural metastasis. Therefore, surgical indication must be decided carefully. Systemic chemotherapy or radiotherapy is useful to treat BSCCE metastasis, however, appropriate, but which agents and their regimens are appropriate is not clear. Concurrent chemotherapy using cisplatin and 5-fluorouracil and radiotherapy for pulmonary BSCCE metastases may provide curative therapy and should be considered.
  
  
  CONCLUSIONS
  This report describes a case of recurrent pulmonary metastasis after pulmonary resection of BSCCE metastasis, successfully treated by concurrent chemotherapy and radiotherapy. Further studies are required to establish the indications and efficacy of these therapeutic approaches.
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Ishida
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan. Electronic address: torun@med.tohoku.ac.jp.
authors.forename: Toru
authors.initials: T
authors.lastname: Nakano
authors.affiliation: Department of Pathology, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Fumiyoshi
authors.initials: F
authors.lastname: Fujishima
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kamei
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Taniyama
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Sakurai
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Chiaki
authors.initials: C
authors.lastname: Sato
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Fukutomi
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Kuroudo
authors.initials: K
authors.lastname: Kamiya
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Ozawa
authors.affiliation: Department of Pathology, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Hironobu
authors.initials: H
authors.lastname: Sasano
authors.affiliation: Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai-shi, Miyagi 980-8574, Japan.
authors.forename: Noriaki
authors.initials: N
authors.lastname: Ohuchi
keywords: Basaloid squamous cell carcinoma; Chemoradiotherapy; Oesophagus; Pulmonary metastasis; Surgery