title: Antidiabetic Effects of Simple Phenolic Acids: A Comprehensive Review.
abstract: Diabetes mellitus (DM) has become a major public health threat across the globe. Current antidiabetic therapies are based on synthetic drugs that very often have side effects. It has been widely acknowledged that diet plays an important role in the management of diabetes. Phenolic acids are widely found in daily foods such as fruits, vegetables, cereals, legumes, and wine and they provide biological, medicinal, and health properties. Simple phenolic acids have been shown to increase glucose uptake and glycogen synthesis, improve glucose and lipid profiles of certain diseases (obesity, cardiovascular diseases, DM, and its complication). The current review is an attempt to list out the antidiabetic effects of simple phenolic acids from medicinal plants and botanical foods.
authors.affiliation: Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai, Guangdong, 519085, China.
authors.forename: Ramachandran
authors.initials: R
authors.lastname: Vinayagam
authors.affiliation: Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai, Guangdong, 519085, China.
authors.forename: Muthukumaran
authors.initials: M
authors.lastname: Jayachandran
authors.affiliation: Food Science and Technology Program, Beijing Normal University-Hong Kong Baptist University United International College, Zhuhai, Guangdong, 519085, China.
authors.forename: Baojun
authors.initials: B
authors.lastname: Xu
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004032:Diet; D002523:Edible Grain / Q000737:chemistry; D007887:Fabaceae / Q000737:chemistry; D005638:Fruit / Q000737:chemistry; D006801:Humans; D062385:Hydroxybenzoates / Q000494:pharmacology*; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D018384:Oxidative Stress; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D000975:Antioxidants; D062385:Hydroxybenzoates; D007004:Hypoglycemic Agents; C017616:phenolic acid
keywords: antidiabetic; diabetes mellitus; glucose; insulin; phenolic acid