title: Aggressive Metaplastic Carcinoma of the Breast with Osteoclastic Giant Cells.
abstract: Metaplastic carcinoma of the breast is an uncommon type of malignancy that is aggressive but can mimic other benign breast neoplastic processes on imaging. We present a case of a young female patient who presented with a rapidly progressing metaplastic carcinoma with osteoclastic giant cells subtype. There have been only very rare published reports of this pathologic subtype of metaplastic carcinoma containing osteoclastic giant cells.
authors.affiliation: Department of Radiology, University of California, Davis Medical Center, Sacramento, USA.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Khong
authors.affiliation: Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, USA.
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, USA.
authors.forename: Mary
authors.initials: M
authors.lastname: Tomic
authors.affiliation: Department of Radiology, University of California, Davis Medical Center, Sacramento, USA.
authors.forename: Karen
authors.initials: K
authors.lastname: Lindfors
authors.affiliation: Department of Radiology, University of California, Davis Medical Center, Sacramento, USA.
authors.forename: Shadi
authors.initials: S
authors.lastname: Aminololama-Shakeri
mesh_terms: D000328:Adult; D062005:Biopsy, Large-Core Needle; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003937:Diagnosis, Differential; D005260:Female; D015726:Giant Cells / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D020360:Neoadjuvant Therapy; D016896:Treatment Outcome; D014463:Ultrasonography
keywords: breast; breast magnetic resonance imaging; breast ultrasound; mammography; metaplastic breast cancer; osteoclastic giant cells