title: Gender Variation in the Risk Factors with Ischemic Stroke: Bangladesh Perspective.
abstract: It is suggested in different studies that gender has a great impact on the distribution of risk factors of stroke. This study aims at determining the gender differences in risk factors of acute ischemic stroke among male and female patients. Data extracted for this study were taken from a case control study which was carried out in the departments of Neurology and Medicine of Dhaka Medical College Hospital (DMCH) and Shaheed Suhrawardy Medical College Hospital (ShSMCH) Dhaka from July 2009 to June 2011. We collected data of 125 patients with ischemic stroke and 129 healthy controls from the primary source. All secondary data were divided on the basis of gender. Among all male respondents 70 stroke patients were considered as case and 72 healthy respondents were considered as control and in female group 55 were stroke patients (case) and 57 were healthy control. Risk factors of stroke for male and female were evaluated separately. After multivariate analysis ever smoking (both present and ex smoker) (adj. OR 3.799, 95% CI 1.416, 10.19), diabetes mellitus (adj. OR 5.687, 95% CI 1.99, 16.26), hypertension (adj. OR 18.53, 95% CI 6.43, 53.4) and total cholesterol (adj. OR 1.017, 95% CI 1.01, 1.03) were found significant predictors for stroke in male whereas diabetes mellitus (adj. OR 6.989, 95% CI 1.54, 31.64), hypertension (adj. OR 17.85, 95% CI 5.1, 62.38), serum low density lipoprotein (LDL) (adj. OR 1.04, 95% CI 1.013, 1.07) and serum triglyceride (TG) (adj. OR 1.012, 95% CI 1.004, 1.02) were found significant in female. Besides taking the controlling measure for hypertension and diabetes mellitus, life style modification is an important factor to prevent stroke in both sexes.
authors.affiliation: Dr Md Atiqul Haque, Associate Professor, Department of Public Health and Informatics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
authors.forename: M A
authors.initials: MA
authors.lastname: Haque
authors.forename: M I
authors.initials: MI
authors.lastname: Khalil
authors.forename: N
authors.initials: N
authors.lastname: Barman
authors.forename: M T
authors.initials: MT
authors.lastname: Islam
authors.forename: M
authors.initials: M
authors.lastname: Mannan
authors.forename: M A
authors.initials: MA
authors.lastname: Rob
authors.forename: A
authors.initials: A
authors.lastname: Saha
authors.forename: M A
authors.initials: MA
authors.lastname: Hossain
mesh_terms: D000368:Aged; D001459:Bangladesh; D002545:Brain Ischemia / Q000209:etiology*; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D048909:Diabetes Complications / Q000209:etiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012727:Sex Characteristics; D020521:Stroke / Q000209:etiology*
chemical_list: D002784:Cholesterol