title: Evaluation of Head and Neck Tumors with Functional MR Imaging.
abstract: Head and neck cancer is one of the most common cancers worldwide. MR imaging-based diffusion and perfusion techniques enable the noninvasive assessment of tumor biology and physiology, which supplement information obtained from standard structural scans. Diffusion and perfusion MR imaging techniques provide novel biomarkers that can aid monitoring in pretreatment, during treatment, and posttreatment stages to improve patient selection for therapeutic strategies; provide evidence for change of therapy regime; and evaluate treatment response. This review discusses pertinent aspects of the role of diffusion and perfusion MR imaging and computational analysis methods in studying head and neck cancer.
authors.affiliation: Department of Radiology, Maastricht University Medical Center, PO Box 5800, Maastricht 6202 AZ, The Netherlands. Electronic address: jacobus.jansen@mumc.nl.
authors.forename: Jacobus F A
authors.initials: JFA
authors.lastname: Jansen
authors.affiliation: Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
authors.forename: Carlos
authors.initials: C
authors.lastname: Parra
authors.affiliation: Department of Radiation Oncology, University of Washington, 4921 Parkview Pl, St Louis, MO 63110, USA.
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
authors.forename: Amita
authors.initials: A
authors.lastname: Shukla-Dave
mesh_terms: D038524:Diffusion Magnetic Resonance Imaging / Q000639:trends*; D006258:Head and Neck Neoplasms / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000639:trends*; D064847:Multimodal Imaging / Q000639:trends; D009389:Neovascularization, Pathologic / Q000150:complications / Q000175:diagnosis*
keywords: Data processing; Diffusion; Head and neck cancer; MR imaging; Perfusion