title: Primary pulmonary monophasic synovial sarcoma: Evading diagnosis.
abstract: Primary pulmonary synovial sarcoma is a very rare tumor, thus there is no consensus as to the most appropriate management. A 78-year-old man presented with nonspecific symptoms of weight loss and shortness of breath. Imaging confirmed a large right-sided mass and accompanying pleural effusion. Strong 18F-fluorodeoxyglucose uptake was found on positron-emission tomography. The preoperative work-up and intraoperative frozen section were inconclusive. Immunohistochemistry and molecular analysis confirmed the diagnosis of primary pulmonary monophasic synovial sarcoma.
authors.affiliation: Department of Cardiothoracic Surgery, University Hospital of North Midlands, Stoke-On-Trent, UK marcustaylor@outlook.com.
authors.forename: Marcus
authors.initials: M
authors.lastname: Taylor
authors.affiliation: Department of Cardiothoracic Surgery, University Hospital of North Midlands, Stoke-On-Trent, UK.
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Srinivasan
authors.affiliation: Department of Cardiothoracic Surgery, University Hospital of North Midlands, Stoke-On-Trent, UK.
authors.forename: Qamar
authors.initials: Q
authors.lastname: Abid
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis / Q000235:genetics; D019788:Fluorodeoxyglucose F18; D005629:Frozen Sections; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000737:chemistry / Q000150:complications / Q000175:diagnosis* / Q000235:genetics / Q000601:surgery; D008297:Male; D025202:Molecular Diagnostic Techniques; D064847:Multimodal Imaging / Q000379:methods; D016066:Pleural Effusion, Malignant / Q000209:etiology; D011013:Pneumonectomy; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D013584:Sarcoma, Synovial / Q000737:chemistry / Q000150:complications / Q000175:diagnosis* / Q000235:genetics / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Immunohistochemistry; Lung neoplasms; Sarcoma; Translocation; genetic; synovial