title: Fetal Brain Magnetic Resonance Imaging Findings In Congenital Cytomegalovirus Infection With Postnatal Imaging Correlation.
abstract: Fetal brain magnetic resonance imaging (MRI) is a powerful tool in the diagnosis of symptomatic congenital cytomegalovirus infection, requiring a detailed search for specific features. A combination of anterior temporal lobe abnormalities, white matter lesions, and polymicrogyria is especially predictive. Fetal MRI may provide a unique opportunity to detect anterior temporal cysts and occipital horn septations, as dilation of these areas may decrease later in development. Cortical migration abnormalities, white matter abnormalities, cerebellar dysplasia, and periventricular calcifications are often better depicted on postnatal imaging but can also be detected on fetal MRI. We present the prenatal brain MRI findings seen in congenital cytomegalovirus infection and provide postnatal imaging correlation, highlighting the evolution of findings at different times in prenatal and postnatal developments.
authors.affiliation: Department of Medical Imaging, Nemours/A.I. duPont Hospital for Children, Wilmington, DE. Electronic address: lauren.averill@nemours.org.
authors.forename: Lauren W
authors.initials: LW
authors.lastname: Averill
authors.affiliation: Department of Medical Imaging, Nemours/A.I. duPont Hospital for Children, Wilmington, DE.
authors.forename: Vinay V R
authors.initials: VV
authors.lastname: Kandula
authors.affiliation: Department of Medical Imaging, Nemours/A.I. duPont Hospital for Children, Wilmington, DE.
authors.forename: Yakup
authors.initials: Y
authors.lastname: Akyol
authors.affiliation: Department of Radiology (Medical Imaging), Nemours Children׳s Hospital, Orlando, FL.
authors.forename: Monica
authors.initials: M
authors.lastname: Epelman
mesh_terms: D019465:Craniofacial Abnormalities / Q000473:pathology*; D003586:Cytomegalovirus Infections / Q000151:congenital* / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000473:pathology*; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011296:Prenatal Diagnosis / Q000379:methods*; D013223:Statistics as Topic