title: LEOPARD Syndrome.
abstract: LEOPARD syndrome (LS) is an autosomal dominantly inherited or sporadic disorder of variable penetrance and expressivity. The acronym LEOPARD stands for its cardinal clinical features including Lentigines, Electrocardiographic conduction abnormalities, Ocular hypertelorism, Pulmonary stenosis, Abnormalities of genitalia, Retardation of growth, and Deafness. We present herein a patient with LEOPARD syndrome and distinctive features. It was noteworthy that our patient presented with the concern of generalized lentiginosis and subsequent evaluation revealed that the patient had LEOPARD syndrome. In this report we would like to highlight the importance of detailed clinical examination and appropriate imaging in patients with multiple lentigines.
authors.affiliation: R.G.Kar Medical College, Kolkata. dr_skghosh@yahoo.co.in.
authors.forename: Sudip Kumar
authors.initials: SK
authors.lastname: Ghosh
authors.forename: Biswajit
authors.initials: B
authors.lastname: Majumdar
authors.forename: Olympia
authors.initials: O
authors.lastname: Rudra
authors.forename: Sougat
authors.initials: S
authors.lastname: Chakraborty
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D044542:LEOPARD Syndrome / Q000175:diagnosis*; D012867:Skin / Q000473:pathology*; D016277:Ventricular Function, Left / Q000502:physiology*; D055815:Young Adult