title: [Pertussis vaccines: acellular versus whole cell. Perhaps a return to the past?].
abstract: The resurgence of pertussis in the world and in our country has questioned the effectiveness of cellular and acellular vaccines. The reason why pertussis has not been controlled or eliminated after 70 years of implementation of the vaccination is probably multifactorial. This article, on the basis of questions and answers, describes the benefits and limitations of both cellular and acellular vaccines and suggests new strategies of vaccination in childhood. It is a fact that the currently applied vaccination does not eliminate the circulation of Bordetella pertussis in the community. Perhaps the introduction of vaccines with live B. pertussis, inhalation, will be able to eliminate the disease around the world.
authors.forename: José
authors.initials: J
authors.lastname: Cofré
mesh_terms: D001886:Bordetella pertussis / Q000276:immunology*; D002677:Chile; D006801:Humans; D010567:Pertussis Vaccine / Q000008:administration & dosage* / Q000009:adverse effects; D014611:Vaccination; D022282:Vaccines, Acellular / Q000008:administration & dosage / Q000009:adverse effects; D014917:Whooping Cough / Q000517:prevention & control*
chemical_list: D010567:Pertussis Vaccine; D022282:Vaccines, Acellular