title: Nurse-Led Programs to Facilitate Enrollment to Children's Oncology Group Cancer Control Trials.
abstract: The progress made over the past 50 years in disease-directed clinical trials has significantly increased cure rates for children and adolescents with cancer. The Children's Oncology Group (COG) is now conducting more studies that emphasize improving quality of life for young people with cancer. These types of clinical trials are classified as cancer control (CCL) studies by the National Cancer Institute and require different resources and approaches to facilitate adequate accrual and implementation at COG institutions. Several COG institutions that had previously experienced problems with low accruals to CCL trials have successfully implemented local nursing leadership for these types of studies. Successful models of nurses as institutional leaders and "champions" of CCL trials are described.
authors.affiliation: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA mhaugen@luriechildrens.org.
authors.forename: Maureen
authors.initials: M
authors.lastname: Haugen
authors.affiliation: The George Washington University School of Nursing, Washington, DC, USA Children's National Health System, Washington, DC, USA.
authors.forename: Katherine Patterson
authors.initials: KP
authors.lastname: Kelly
authors.affiliation: University of Michigan, Ann Arbor, MI, USA.
authors.forename: Marcia
authors.initials: M
authors.lastname: Leonard
authors.affiliation: The Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: Denise
authors.initials: D
authors.lastname: Mills
authors.affiliation: The Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: Lillian
authors.initials: L
authors.lastname: Sung
authors.affiliation: Children's National Health System, Washington, DC, USA.
authors.forename: Catriona
authors.initials: C
authors.lastname: Mowbray
authors.affiliation: University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Wendy
authors.initials: W
authors.lastname: Landier
mesh_terms: D000293:Adolescent; D035843:Biomedical Research / Q000458:organization & administration*; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007223:Infant; D007857:Leadership; D008297:Male; D009369:Neoplasms / Q000503:physiopathology*; D024802:Nurse's Role; D009859:Oncology Nursing / Q000458:organization & administration*; D018579:Patient Selection; D010371:Pediatric Nursing / Q000458:organization & administration*; D014481:United States
keywords: cancer control clinical trials; nurses as leaders; pediatric oncology