title: Minimally Invasive Neurosurgery for Epilepsy Using Stereotactic MRI Guidance.
abstract: Medically refractory epilepsy is associated with significant morbidity and mortality. Surgery is a safe and effective option for some patients, however the opportunity exists to develop less invasive and more effective surgical options. To this end, multiple minimally invasive, image-guided techniques have been applied to the treatment of epilepsy. These techniques can be divided into thermoablative and disconnective techniques. Each has been described in the treatment of epilepsy only in small case series. Larger series and longer follow up periods will determine each option's place in the surgical armamentarium for the treatment of refractory epilepsy but early results are promising.
authors.affiliation: Department of Neurological Surgery, Washington University School of Medicine, Campus Box 8057, 660 South Euclid Avenue, St Louis, MO 63110, USA. Electronic address: skbandt@gmail.com.
authors.forename: S Kathleen
authors.initials: SK
authors.lastname: Bandt
authors.affiliation: Department of Neurological Surgery, Washington University School of Medicine, Campus Box 8057, 660 South Euclid Avenue, St Louis, MO 63110, USA; Department of Biomedical Engineering, Washington University, St Louis, MO 63110, USA; Center for Innovation in Neuroscience and Technology, Washington University School of Medicine, St Louis, MO 63110, USA.
authors.forename: Eric C
authors.initials: EC
authors.lastname: Leuthardt
mesh_terms: D001931:Brain Mapping / Q000379:methods*; D004827:Epilepsy / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods*; D013238:Stereotaxic Techniques; D016896:Treatment Outcome
keywords: Epilepsy surgery; Laser ablation; Medically refractory epilepsy; Stereotactic guidance