title: Hepatobiliary Tumors: Update on Diagnosis and Management.
abstract: Tumors of the liver and biliary tree, mainly hepatocellular carcinoma and cholangiocarcinoma, are the second leading cause of cancer related death worldwide and the sixth leading cause of cancer related death among men in developed countries. Recent developments in biomarkers and imaging modalities have enhanced early detection and accurate diagnosis of these highly fatal malignancies. These advances include serological testing, micro-ribonucleic acids, fluorescence in situ hybridization, contrast-enhanced ultrasound, and hepatobiliary-phase magnetic resonance imaging. In addition, there have been major developments in the surgical and nonsurgical management of these tumors, including expansion of the liver transplantation criteria, new locoregional treatments, and molecularly targeted therapies. In this article, we review various types of hepatobiliary tumors and discuss new developments in their diagnosis and management.
authors.affiliation: Department of internal medicine, Albany medical center, Albany, NY, USA.
authors.forename: Ghassan
authors.initials: G
authors.lastname: Kabbach
authors.affiliation: Department of internal medicine, Albany medical center, Albany, NY, USA.
authors.forename: Hussein A
authors.initials: HA
authors.lastname: Assi
authors.affiliation: Department of radiology, Albany medical center, Albany, NY, USA.
authors.forename: George
authors.initials: G
authors.lastname: Bolotin
authors.affiliation: Department of radiology, Albany medical center, Albany, NY, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Schuster
authors.affiliation: Department of pathology, Albany medical center, Albany, NY, USA.
authors.forename: Hwa Jeong
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of internal medicine, Division of gastroenterology, Albany medical center, Albany, NY, USA.
authors.forename: Micheal
authors.initials: M
authors.lastname: Tadros
keywords: Cholangiocarcinoma; Diagnosis; Hepatobiliary tumors; Hepatocellular carcinoma; Liver cancer; Management; Treatment