title: Intracranial benign fibrous histiocytoma mimicking parasagittal meningioma: report of two cases and review of literature.
abstract: Primary benign fibrous histiocytoma involving the central nervous system is an exceedingly rare tumor with most cases originating from the dura or parenchymal tissue. Diagnosis of primary benign fibrous histiocytoma is difficult due to its confusing histopathological characteristics. Two cases of primary intracranial benign fibrous histiocytoma mimicking parasagittal meningioma are presented in this report. Both tumors were gross totally resected and the patients showed no evidence of recurrence at follow-up of 12 months. The clinical features and prognosis of this rare tumor that were reported previously in the literature were also reviewed. Histopathological examination coupled with immunohistochemical staining is proved to be the convincing diagnostic method for the primary benign fibrous histiocytoma. Surgical resection is the recommendation for the therapy of the tumor.
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University Beijing 100050, China.
authors.forename: Baoshi
authors.initials: B
authors.lastname: Chen
authors.affiliation: Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University Beijing 100050, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University Beijing 100050, China.
authors.forename: Yanwei
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University Beijing 100050, China ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University Beijing 100050, China.
authors.forename: Gan
authors.initials: G
authors.lastname: You
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University Beijing 100050, China.
authors.forename: Jiangfei
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University Beijing 100050, China.
authors.forename: Junmei
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University Beijing 100050, China.
authors.forename: Zhongli
authors.initials: Z
authors.lastname: Jiang
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University Beijing 100050, China ; Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University Beijing 100050, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008577:Meningeal Neoplasms / Q000473:pathology*; D008579:Meningioma / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: Fibrous histiocytoma; intracranial tumors; meningioma