title: Self-assembling tryptophan-based designer peptides as intracellular delivery vehicles.
abstract: A series of tryptophan-based peptides W1a, b-W4a, b, with diverse architectures were designed and synthesized. These tryptophan containing peptides can self-assemble to spherical particle. This self-assembled system was demonstrated to encapsulate rhodamine B and penetrate the cell membrane.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Delhi (IITD), Hauz Khas, New Delhi 110016, India.
authors.forename: Ishanki
authors.initials: I
authors.lastname: Bhardwaj
authors.affiliation: Product Development Cell, National Institute of Immunology (NII), Aruna Asaf Ali Marg, New Delhi 110067, India.
authors.forename: Divya
authors.initials: D
authors.lastname: Jha
authors.affiliation: Product Development Cell, National Institute of Immunology (NII), Aruna Asaf Ali Marg, New Delhi 110067, India.
authors.forename: Prasad
authors.initials: P
authors.lastname: Admane
authors.affiliation: Product Development Cell, National Institute of Immunology (NII), Aruna Asaf Ali Marg, New Delhi 110067, India.
authors.forename: Amulya K
authors.initials: AK
authors.lastname: Panda
authors.affiliation: Department of Chemistry, Indian Institute of Technology Delhi (IITD), Hauz Khas, New Delhi 110016, India. Electronic address: haridasv@iitd.ac.in.
authors.forename: V
authors.initials: V
authors.lastname: Haridas
mesh_terms: D000818:Animals; D002460:Cell Line; D050091:Dendrimers / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D051379:Mice; D010455:Peptides / Q000737:chemistry*; D012235:Rhodamines / Q000008:administration & dosage*; D014364:Tryptophan / Q000737:chemistry*
chemical_list: D050091:Dendrimers; D004337:Drug Carriers; D010455:Peptides; D012235:Rhodamines; D014364:Tryptophan; C029773:rhodamine B
keywords: Encapsulation; Peptide; Self-assembly; Spherical assembly; Tryptophan