title: Metastatic lung adenocarcinoma to the bladder: A case report.
abstract: Urothelial cancer is the most frequently diagnosed type of malignant tumor in the bladder, of which primary adenocarcinoma accounts for a small percentage. Secondary malignancies, in particular metastatic adenocarcinoma from the lung, are exceedingly rare, with only six cases previously reported in the literature. The present study describes the case of a 71-year-old Chinese male patient with known lung cancer for >2 years, who was diagnosed with metastatic adenocarcinoma to the bladder. The histopathological characteristics and immunohistochemical features of the patient are reported. It was proposed that pathologists should consider the possibility of metastatic adenocarcinoma from the lung, rather than assume a diagnosis of primary adenocarcinoma of the bladder or direct invasion of adenocarcinoma from the surrounding organs. Furthermore, it is essential to determine the medical history of each patient and observe the immunohistochemical features of all tumors prior to diagnosis.
authors.affiliation: Department of Pathology, People's Liberation Army 205 Hospital, Jinzhou, Liaoning 121000, P.R. China.
authors.forename: Hai-Jun
authors.initials: HJ
authors.lastname: Ye
authors.affiliation: Department of Research Service, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
authors.forename: Jian
authors.initials: J
authors.lastname: Ma
authors.affiliation: Department of Pathology, People's Liberation Army 205 Hospital, Jinzhou, Liaoning 121000, P.R. China.
authors.forename: Ying-Jie
authors.initials: YJ
authors.lastname: Liu
authors.affiliation: Department of Pathology, People's Liberation Army 205 Hospital, Jinzhou, Liaoning 121000, P.R. China.
authors.forename: Xiao-Fei
authors.initials: XF
authors.lastname: Ye
authors.affiliation: Department of Research Service, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
authors.forename: Li-Wang
authors.initials: LW
authors.lastname: Zhang
authors.affiliation: Department of Infectious Disease, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
authors.forename: Jin-Ge
authors.initials: JG
authors.lastname: Li
keywords: bladder; lung adenocarcinoma; metastatic; thyroid transcription factor-1