title: Comparison of Consanguinity between Parents of Hearing Impaired and Public School Children with Estimation of Risk.
abstract: Deafness is the hidden disability and the most common human sensory defects which lead to poor educational and employment prospects of childhood. Is there any association of consanguinity and hearing loss or are there any difference of association of consanguinity and hearing loss in specialized and public school children and how much risk is associated?--were the research questions of this study. Total 428 participants have been selected randomly. Hearing impaired were 186 participants and 242 participants were normal hearing school boy. This was a case control, analytical, hypotheses testing study. In normal public school children group, consanguinity was present in 2.5% parents. The rest were married with non relatives. In parents of hearing impaired children group, consanguinity was very high (17.2%). Pearson chi-square test and Odds ratio analysis was done. The value was less than 0.05 and ratio was 8.173. The 'p' value of Pearson chi-square test was less than 0.05. So, the test was highly significant at 95% confidence interval. Odds ratio showed that the risk of profound sensorineural hearing loss in the baby of parents of consanguineous marriages 8.173 times higher than that of non consanguineous marriages.
authors.affiliation: Dr Md Abdus Sattar, Associate Professor, Department of Otolaryngology & Head-Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
authors.forename: M A
authors.initials: MA
authors.lastname: Sattar
authors.forename: M T
authors.initials: MT
authors.lastname: Sultana
mesh_terms: D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002648:Child; D003241:Consanguinity; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D016017:Odds Ratio; D010290:Parents; D012307:Risk Factors