title: Reply: Risk-based Heterogeneity of Treatment Effect in Trials and Implications for Surveillance of Clinical Effectiveness Using Regression Discontinuity Designs.
authors.affiliation: 1 Monash University Melbourne, Victoria, Australia.|2 University of Michigan Ann Arbor, Michigan.|3 VA Ann Arbor Health System Ann Arbor, Michigan.
authors.forename: Theodore J
authors.initials: TJ
authors.lastname: Iwashyna
authors.affiliation: 2 University of Michigan Ann Arbor, Michigan.
authors.forename: James F
authors.initials: JF
authors.lastname: Burke
authors.affiliation: 2 University of Michigan Ann Arbor, Michigan.|3 VA Ann Arbor Health System Ann Arbor, Michigan.
authors.forename: Jeremy B
authors.initials: JB
authors.lastname: Sussman
authors.affiliation: 2 University of Michigan Ann Arbor, Michigan.|3 VA Ann Arbor Health System Ann Arbor, Michigan.
authors.forename: Hallie C
authors.initials: HC
authors.lastname: Prescott
authors.affiliation: 2 University of Michigan Ann Arbor, Michigan.|3 VA Ann Arbor Health System Ann Arbor, Michigan.
authors.forename: Rodney A
authors.initials: RA
authors.lastname: Hayward
authors.affiliation: 4 University of Pittsburgh Pittsburgh, Pennsylvania.
authors.forename: Derek C
authors.initials: DC
authors.lastname: Angus
mesh_terms: D003422:Critical Care / Q000379:methods* / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data*; D012131:Respiratory Insufficiency / Q000628:therapy*; D018805:Sepsis / Q000628:therapy*