title: Surgical Treatment of Small Bowel Neuroendocrine Tumors.
abstract: Neuroendocrine tumors of the small bowel are rare, slow-growing malignancies that commonly metastasize to nodes at the root of the mesentery and the liver. Liver metastases are associated with carcinoid syndrome. Mesenteric nodal masses can cause bowel obstruction, intestinal angina, or variceal hemorrhage. Patients die of liver failure or bowel obstruction. Primary resection is associated with improved survival rates. Selected patients may benefit from liver debulking operations. Liver resection has excellent survival rates even in the event of an incomplete resection, as well as improvement in hormonal symptoms. Radiofrequency ablation can help to preserve hepatic parenchyma during resection.
authors.affiliation: Department of Surgery, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Mail Code L 619, Portland, OR 97329, USA.
authors.forename: Heather A
authors.initials: HA
authors.lastname: Farley
authors.affiliation: Division of Surgical Oncology, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Mail Code L 619, Portland, OR 97329, USA. Electronic address: pommierr@ohsu.edu.
authors.forename: Rodney F
authors.initials: RF
authors.lastname: Pommier
mesh_terms: D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology / Q000601:surgery*; D007421:Intestine, Small / Q000473:pathology / Q000601:surgery*; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local; D018358:Neuroendocrine Tumors / Q000473:pathology / Q000601:surgery*; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: Ablation; Liver; Mesenteric nodal mass; Metastasis; Neuroendocrine; Primary tumor; Resection