title: Application of ionic liquid-based dispersive liquid phase microextraction for highly sensitive simultaneous determination of three endocrine disrupting compounds in food packaging.
abstract: Ionic liquid (IL) dispersive liquid-liquid microextraction (DLLME) method was successfully developed for extracting three endocrine disrupting compounds (EDCs) (bisphenol A, bisphenol AF and bisphenol AP) from the food packaging. 1-Octyl-3-methylimidazoliumhexafluorophosphate ([C8MIM][PF6]) was selected as extraction solution. The extraction procedure did not require a dispersive solvent. Three EDCs extraction kinetics were found to be very fast and the equilibrium was attained within 3.0 min following the pseudo-first-order model. The H-bonding and hydrophobic interactions play an important role in the partitioning of EDCs into IL from aqueous solution. The recovered IL could be reused for three runs without significant loss of extraction efficiencies. The spiked recoveries of three targets in food packaging were in the range of 97.8-103.1%. The limits of detection ranged from 0.50 to 1.50 ng mL(-1) (S/N=3). As a result, this method has been successfully applied for the sensitive detection of three EDCs in real samples.
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang, Liaoning 110036, People's Republic of China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Wang
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang, Liaoning 110036, People's Republic of China.
authors.forename: Danfeng
authors.initials: D
authors.lastname: Zhang
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang, Liaoning 110036, People's Republic of China.
authors.forename: Xu
authors.initials: X
authors.lastname: Xu
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang, Liaoning 110036, People's Republic of China. Electronic address: zhanglei63@126.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
mesh_terms: D001559:Benzhydryl Compounds / Q000032:analysis*; D052244:Endocrine Disruptors / Q000032:analysis*; D018857:Food Packaging; D052578:Ionic Liquids / Q000737:chemistry*; D007477:Ions; D057230:Limit of Detection; D059627:Liquid Phase Microextraction / Q000379:methods*; D010636:Phenols / Q000032:analysis*; D012997:Solvents / Q000737:chemistry; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D052244:Endocrine Disruptors; D052578:Ionic Liquids; D007477:Ions; D010636:Phenols; D012997:Solvents; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Bisphenol A; Bisphenol AF; Bisphenol AP; Dispersive liquid–liquid microextraction; Ionic liquid