title: Relation between periodontitis and helicobacter pylori infection.
abstract: OBJECTIVE
  The correlation between periodontitis and Helicobacter pylori (H. pylori) infection in the mouth was analyzed.
  
  
  METHODS
  70 elderly patients with periodontitis treated at our hospital from January 2013 to December 2014 were recruited. Dental plaques and gargle were collected for H. pylori detection using PCR technique. Periodontal health status of the patients was recorded. 70 control cases with healthy periodontium were also included. The symptoms of H. pylori infection in the mouth were compared between the two groups, and the results were analyzed statistically.
  
  
  RESULTS
  The positive rate of urease C gene of H. pylori in the periodontitis group was 71.4%; the positive rate of cagA gene was 35.7%. The positive rate of urease C gene of H. pylori in the control group was 34.3% and that of cagA gene was 12.9%. The two groups did not show significant differences in these two indicators (P<0.05). The positive detection rate of urease C gene of H. pylori in subgingival plaques was higher than that in supragingival plaques, and the difference was of statistical significance (P<0.05). The positive detection rate of H. pylori in patients with moderate and severe periodontitis was obviously higher than that of patients with mild periodontitis (P<0.05).
  
  
  CONCLUSIONS
  Periodontal health status of elderly people with periodontitis correlated with H. pylori infection in the stomach.
authors.affiliation: Department of Conservative Dentistry, Affiliated Hospital of Stomatology, Medical College, Zhejiang University Hangzhou 310006, China.
authors.forename: Pei
authors.initials: P
authors.lastname: Zheng
authors.affiliation: Department of Neurology, The Second Affiliated Hospital of Zhejiang Chinese Medical University Hangzhou 310015, China.
authors.forename: Weiying
authors.initials: W
authors.lastname: Zhou
keywords: Helicobacter; Periodontitis; elderly people; pylorus; stomach