title: Dental anomalies inside the cleft region in individuals with nonsyndromic cleft lip with or without cleft palate.
abstract: BACKGROUND
  Individuals with nonsyndromic cleft lip with or without cleft palate (NSCL±P) present high frequency of dental anomalies, which may represent complicating factors for dental treatment. The aim of this study was to investigate the prevalence of dental anomalies inside cleft area in a group of Brazilians with NSCL±P.
  
  
  METHODS
  Retrospective analysis of 178 panoramic radiographs of patients aged from 12 to 45 years old and without history of tooth extraction or orthodontic treatment was performed. Association between cleft type and the prevalence of dental anomalies was assessed by chi-square test with a significance level set at p≤ 0.05.
  
  
  RESULTS
  Dental anomalies were found in 88.2% (n=157) of the patients. Tooth agenesis (47.1%), giroversion (20%) and microdontia (15.5%) were the most common anomalies. Individuals with unilateral complete cleft lip and palate (CLP, p<0.0001), bilateral complete CLP (p=0.0002) and bilateral incomplete CLP (p< 0.0001) were more affected by tooth agenesis than individuals with other cleft types. The maxillary lateral incisors were the most affected teeth (p<0.0001).
  
  
  CONCLUSIONS
  The present study revealed a high frequency of dental anomalies inside cleft region in NSCL±P patients, and further demonstrated that patients with unilateral complete CLP and bilateral incomplete CLP were frequently more affected by dental anomalies. Moreover, our results demonstrate that dental anomalies should be considered during dental treatment planning of individuals affected by NSCL±P.
authors.affiliation: Department of Basic Science, Bahiana School of Medicine and Public Health, Av. Silveira Martins, no 3386, Cabula, CEP: 41150-100, Salvador, Bahia, Brazil, srareis@bahiana.edu.br.
authors.forename: Jamile
authors.initials: J
authors.lastname: Sá
authors.forename: Luana
authors.initials: L
authors.lastname: Araújo
authors.forename: Laís
authors.initials: L
authors.lastname: Guimarães
authors.forename: Samário
authors.initials: S
authors.lastname: Maranhão
authors.forename: Gabriela
authors.initials: G
authors.lastname: Lopes
authors.forename: Alena
authors.initials: A
authors.lastname: Medrado
authors.forename: Ricardo
authors.initials: R
authors.lastname: Coletta
authors.forename: Silvia
authors.initials: S
authors.lastname: Reis
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002971:Cleft Lip / Q000150:complications*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D014071:Tooth Abnormalities / Q000150:complications* / Q000453:epidemiology*; D055815:Young Adult