title: Medicinal-Induced Behavior Disorders.
abstract: Commonly used medications can have neuropsychiatric and behavioral effects that may be idiosyncratic or metabolic in nature, or a function of interactions with other drugs, toxicity, or withdrawal. This article explores an approach to the patient with central nervous system toxicity, depending on presentation of sedation versus agitation and accompanying physical signs and symptoms. The effects of antihypertensives, opioids, antibiotics, antiepileptic agents, steroids, Parkinson's disease medications, antipsychotics, medications for human immunodeficiency virus infection, cancer chemotherapeutics, and immunotherapies are discussed. A look at the prevalence of adverse reactions to medications and the errors underlying such occurrences is included.
authors.affiliation: Department of Neurology, Louisiana State University Health Sciences Center - Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA.
authors.forename: Sai Krishna J
authors.initials: SK
authors.lastname: Munjampalli
authors.affiliation: Department of Neurology, Louisiana State University Health Sciences Center - Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA. Electronic address: delli1@lsuhsc.edu.
authors.forename: Debra E
authors.initials: DE
authors.lastname: Davis
mesh_terms: D017109:Akathisia, Drug-Induced / Q000175:diagnosis*; D000700:Analgesics / Q000009:adverse effects*; D000927:Anticonvulsants / Q000009:adverse effects*; D000959:Antihypertensive Agents / Q000009:adverse effects*; D014150:Antipsychotic Agents / Q000009:adverse effects*; D006801:Humans; D001523:Mental Disorders / Q000139:chemically induced*; D011595:Psychomotor Agitation
chemical_list: D000700:Analgesics; D000927:Anticonvulsants; D000959:Antihypertensive Agents; D014150:Antipsychotic Agents
keywords: Behavioral; Encephalopathy; Medication; Nervous system; Psychiatric; Side effects; Toxicity; Withdrawal