title: Changes in haemostasis and thrombosis associated with thyroid disease: Presentation of 2 cases.
abstract: There is a relationship between thyroid diseases and primary and secondary changes in haemostasis. The most frequent association between them are hypocoagulability states with clinical hypothyroidism and vascular thrombophilia (hypercoagulability and/or hypofibrinolysis) with hyperparathyroidism. However, there are recent studies that have detected changes in haemostasis -primary and secondary- associated with thyroid diseases with normal hormone levels, suggesting other pathogenic mechanisms not yet known. The cases are presented of 2 patients with thyroid disease that required surgery: one multinodular goitre and one papillary carcinoma of the thyroid, both with normal hormone levels. They were shown to have haemostasis disorders during the preoperative work up. These showed a Factor VII deficiency and a Factor XI deficiency along with a thrombotic disease of unknown origin, respectively.
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Complejo Hospitalario Universitario de Albacete, Albacete, España. Electronic address: ana.rodilla.fiz@gmail.com.
authors.forename: A M
authors.initials: AM
authors.lastname: Rodilla Fiz
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Complejo Hospitalario Universitario de Albacete, Albacete, España.
authors.forename: M
authors.initials: M
authors.lastname: Garví López
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Complejo Hospitalario Universitario de Albacete, Albacete, España.
authors.forename: M
authors.initials: M
authors.lastname: Gómez Garrido
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Complejo Hospitalario Universitario de Albacete, Albacete, España.
authors.forename: M
authors.initials: M
authors.lastname: Girón la Casa
mesh_terms: D002291:Carcinoma, Papillary; D006044:Goiter, Nodular; D006487:Hemostasis; D006801:Humans; D013927:Thrombosis; D013959:Thyroid Diseases
keywords: Coagulación; Coagulation; Thyroid; Tiroides