title: Multiplex lateral flow detection and binary encoding enables a molecular colorimetric 7-segment display.
abstract: Multiplex expansion in point-of-care diagnostics usually requires a linear increase of premium commodities such as reagents or space. Here we demonstrate the power of binary and molecular encoding to compress device operations. We describe the first colorimetric 7-segment display on a paper-based biosensor, providing compact and intuitive read-outs for multiplex detections.
authors.affiliation: Inflammation and Healing Research Cluster, Genecology Research Center, School of Science and Engineering, University of the Sunshine Coast, Locked Bag 4, Maroochydore DC, Queensland 4558, Australia. jmacdon1@usc.edu.au.
authors.forename: Jia
authors.initials: J
authors.lastname: Li
authors.affiliation: Inflammation and Healing Research Cluster, Genecology Research Center, School of Science and Engineering, University of the Sunshine Coast, Locked Bag 4, Maroochydore DC, Queensland 4558, Australia. jmacdon1@usc.edu.au and Division of Experimental Therapeutics, Department of Medicine, Columbia University, New York, NY 10032, USA. jm2236@columbia.edu.
authors.forename: Joanne
authors.initials: J
authors.lastname: Macdonald
mesh_terms: D000906:Antibodies / Q000032:analysis; D000937:Antigen-Antibody Reactions; D015374:Biosensing Techniques / Q000379:methods*; D003124:Colorimetry / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D010209:Paper; D019095:Point-of-Care Systems
chemical_list: D000906:Antibodies