title: Racial Disparities in Comorbidities, Complications, and Maternal and Fetal Outcomes in Women With Preeclampsia/eclampsia.
abstract: OBJECTIVE
  The mechanisms leading to worse outcomes in African-American (AA) women with preeclampsia/eclampsia remain unclear. Our objective was to identify racial differences in maternal comorbidities, peripartum characteristics, and maternal and fetal outcomes.
  
  
  RESULTS
  When compared to white women with preeclampsia/eclampsia, AA women had an increased unadjusted risk of inpatient maternal mortality (OR 3.70, 95% CI: 2.19-6.24). After adjustment for covariates, in-hospital mortality for AA women remained higher than that for white women (OR 2.85, 95% CI: 1.38-5.53), while the adjusted risk of death among Hispanic women did not differ from that for white women. We also found an increased risk of intrauterine fetal death (IUFD) among AA women. When compared to white women with preeclampsia, AA women had an increased unadjusted odds of IUFD (OR 2.78, 95% CI: 2.49-3.11), which remained significant after adjustment for covariates (adjusted OR 2.45, 95% CI: 2.14-2.82). In contrast, IUFD among Hispanic women did not differ from that for white women after adjusting for covariates.
  
  
  CONCLUSIONS
  Our data suggest that African-American women are more likely to have risk factors for preeclampsia and more likely to suffer an adverse outcome during peripartum care. Future research should examine whether controlling co-morbidities and other risk factors will help to alleviate racial disparities in outcomes in this cohort of women.
authors.affiliation: a Department of Anesthesia and Critical Care , University of Chicago , Chicago , IL , USA .
authors.forename: Sajid
authors.initials: S
authors.lastname: Shahul
authors.affiliation: a Department of Anesthesia and Critical Care , University of Chicago , Chicago , IL , USA .
authors.forename: Avery
authors.initials: A
authors.lastname: Tung
authors.affiliation: a Department of Anesthesia and Critical Care , University of Chicago , Chicago , IL , USA .
authors.forename: Mohammed
authors.initials: M
authors.lastname: Minhaj
authors.affiliation: a Department of Anesthesia and Critical Care , University of Chicago , Chicago , IL , USA .
authors.forename: Junaid
authors.initials: J
authors.lastname: Nizamuddin
authors.affiliation: c Division of Nephrology , Massachusetts General Hospital, Harvard Medical School , Boston , MA , USA .
authors.forename: Julia
authors.initials: J
authors.lastname: Wenger
authors.affiliation: b Department of Anesthesiology , Beth Israel Deaconess Medical Center, Harvard Medical School , Boston , MA , USA .
authors.forename: Eitezaz
authors.initials: E
authors.lastname: Mahmood
authors.affiliation: b Department of Anesthesiology , Beth Israel Deaconess Medical Center, Harvard Medical School , Boston , MA , USA .
authors.forename: Ariel
authors.initials: A
authors.lastname: Mueller
authors.affiliation: b Department of Anesthesiology , Beth Israel Deaconess Medical Center, Harvard Medical School , Boston , MA , USA .
authors.forename: Shahzad
authors.initials: S
authors.lastname: Shaefi
authors.affiliation: a Department of Anesthesia and Critical Care , University of Chicago , Chicago , IL , USA .
authors.forename: Barbara
authors.initials: B
authors.lastname: Scavone
authors.affiliation: d Department of Medicine , CardioVascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston , MA , USA .
authors.forename: Robb D
authors.initials: RD
authors.lastname: Kociol
authors.affiliation: b Department of Anesthesiology , Beth Israel Deaconess Medical Center, Harvard Medical School , Boston , MA , USA .
authors.forename: Daniel
authors.initials: D
authors.lastname: Talmor
authors.affiliation: e Division of Maternal Fetal Medicine/Department of Obstetrics and Gynecology , University of Chicago , Chicago , IL , USA.
authors.forename: Sarosh
authors.initials: S
authors.lastname: Rana
keywords: Hypertension; epidemiology; mortality