title: Prenatal genetic diagnosis of retinoblastoma--clinical correlates on follow-up.
abstract: Retinoblastoma is the most common malignant intraocular tumor in pediatric age group if undetected leads to ocular mortality. Prenatal diagnosis is an emerging technology to detect fatal diseases in utero such that subsequent management is planned to reduce the ocular morbidity. We describe a case demonstrating the importance of prenatal diagnosis in a child with a strong family history of retinoblastoma and importance of a long-term clinical follow-up in these cases.
authors.forename: Srividya
authors.initials: S
authors.lastname: Neriyanuri
authors.forename: Rajiv
authors.initials: R
authors.lastname: Raman
authors.forename: Pukhraj
authors.initials: P
authors.lastname: Rishi
authors.forename: Kumaramanickavel
authors.initials: K
authors.lastname: Govindasamy
authors.forename: V L
authors.initials: VL
authors.lastname: Ramprasad
authors.affiliation: Department of Vitreo-Retina, Shri Bhagwan Mahavir Vitreoretinal Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.
authors.forename: Tarun
authors.initials: T
authors.lastname: Sharma
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000235:genetics; D011296:Prenatal Diagnosis / Q000379:methods*; D019572:Retinal Neoplasms / Q000175:diagnosis* / Q000235:genetics; D012175:Retinoblastoma / Q000175:diagnosis* / Q000235:genetics