title: Oncologic outcomes after nipple-sparing mastectomy: A single-institution experience.
abstract: BACKGROUND
  Long-term oncologic outcomes in nipple-sparing mastectomy (NSM) continue to be defined. Rates of locoregional recurrence for skin-sparing mastectomy (SSM) and NSM in the literature range from 0% to 14.3%. We investigated the outcomes of NSM at our institution.
  
  
  METHODS
  Patients undergoing NSM at our institution from 2006 to 2014 were identified and outcomes were analyzed.
  
  
  RESULTS
  From 2006 to 2014, 319 patients (555 breasts) underwent NSM. One-hundered and fourty-one patients (237 breasts) had long-term follow-up available. Average patient age and BMI were 47.78 and 24.63. Eighty-four percent of patients underwent mastectomy primarily for a therapeutic indication. Average tumor size was 1.50 cm with the most common histologic type being invasive ductal carcinoma (62.7%) followed by DCIS (23.7%). Average patient follow-up was 30.73 months. There was one (0.8%) incidence of ipsilateral chest-wall recurrence. There were 0.37 complications per patient.
  
  
  CONCLUSIONS
  We examined our institutional outcomes with NSM and found a locoregional recurrence rate of 0.8% with no nipple-areolar complex recurrence. This rate is lower than published rates for both NSM and SSM.
authors.affiliation: Department of Plastic Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Jordan D
authors.initials: JD
authors.lastname: Frey
authors.affiliation: Department of Plastic Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Michael
authors.initials: M
authors.lastname: Alperovich
authors.affiliation: Department of Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Jennifer Chun
authors.initials: JC
authors.lastname: Kim
authors.affiliation: Department of Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Deborah M
authors.initials: DM
authors.lastname: Axelrod
authors.affiliation: Department of Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Richard L
authors.initials: RL
authors.lastname: Shapiro
authors.affiliation: Department of Plastic Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Mihye
authors.initials: M
authors.lastname: Choi
authors.affiliation: Department of Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Freya R
authors.initials: FR
authors.lastname: Schnabel
authors.affiliation: Department of Plastic Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Nolan S
authors.initials: NS
authors.lastname: Karp
authors.affiliation: Department of Surgery, NYU Langone Medical Center, New York, New York.
authors.forename: Amber A
authors.initials: AA
authors.lastname: Guth
mesh_terms: D000328:Adult; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000601:surgery; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects; D008408:Mastectomy / Q000379:methods*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000517:prevention & control; D009367:Neoplasm Staging; D009518:New York / Q000453:epidemiology; D009558:Nipples; D011788:Quality of Life; D016896:Treatment Outcome
keywords: breast cancer; locoregional recurrence; nipple-sparing mastectomy; oncologic; outcomes; reconstructive