title: The first attempt in local excision of anorectal malignant melanoma using transanal endoscopic microsurgery.
abstract: Anorectal malignant melanoma (AMM) is an uncommon malignancy that is thought to arise from melanocytes in the mucosa around the anorectal junction. AMM is commonly misdiagnosed, and definitive preoperative diagnosis is often difficult. The prognosis of AMM is relatively poor. Although radical resection is required for AMM, there is still no consensus at this moment on which surgical approach is preferred. We herein report a rare case of AMM which was treated by transanal endoscopic microsurgery (TEM) in combination with radiotherapy, which resulted in complete excision of the lesion without complications. The successful treatment for this AMM using TEM emphasizes the need to broaden its application in the treatment of various rectal lesions while preserving organ function and decreasing recurrence.
authors.affiliation: Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences No. 1 Shuaifuyuan Hutong of Dongcheng District, Beijing 100730, P. R. China.
authors.forename: Xiangyi
authors.initials: X
authors.lastname: Kong
authors.affiliation: Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences No. 1 Shuaifuyuan Hutong of Dongcheng District, Beijing 100730, P. R. China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences No. 1 Shuaifuyuan Hutong of Dongcheng District, Beijing 100730, P. R. China.
authors.forename: Guole
authors.initials: G
authors.lastname: Lin
authors.affiliation: Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences No. 1 Shuaifuyuan Hutong of Dongcheng District, Beijing 100730, P. R. China.
authors.forename: Dachun
authors.initials: D
authors.lastname: Zhao
authors.affiliation: Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences No. 1 Shuaifuyuan Hutong of Dongcheng District, Beijing 100730, P. R. China.
authors.forename: Huizhong
authors.initials: H
authors.lastname: Qiu
authors.affiliation: Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences No. 1 Shuaifuyuan Hutong of Dongcheng District, Beijing 100730, P. R. China.
authors.forename: Quancai
authors.initials: Q
authors.lastname: Cui
mesh_terms: D000369:Aged, 80 and over; D001005:Anus Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000601:surgery*; D012004:Rectal Neoplasms / Q000601:surgery*; D000067369:Transanal Endoscopic Microsurgery / Q000379:methods*
keywords: Anorectal malignant melanoma; differential diagnosis; transanal endoscopic microsurgery