title: Pulmonary IgG4-related disease and colon adenocarcinoma: possible paraneoplastic syndrome.
abstract: Malignancy has a complicated association with immunoglobulin G4-related disease (IgG4-RD) both being an item in the differential diagnosis as well as malignancy occurring in the background of IgG4-RD in the same organ. However, recently there is evidence of higher rates of distant malignancy in patients with IgG4-RD. Here we report a case of pulmonary IgG4-RD potentially consistent with a paraneoplastic phenomenon which improved with treatment of the underlying colon adenocarcinoma.
authors.affiliation: Division of Rheumatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Megan L
authors.initials: ML
authors.lastname: Krause
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Eunhee S
authors.initials: ES
authors.lastname: Yi
authors.affiliation: Division of Rheumatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Warrington
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D000369:Aged, 80 and over; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D001706:Biopsy; D003110:Colonic Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008171:Lung Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D008297:Male; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D010996:Pleural Effusion / Q000209:etiology / Q000276:immunology; D011241:Prednisone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D007074:Immunoglobulin G; D011241:Prednisone
keywords: immunoglobulin G; interstitial lung diseases; paraneoplastic syndromes