title: VITAMIN D AND BRONCHIAL INFLAMMATION IN ASTHMATIC CHILDREN.
abstract: The role of the vitamin D in calcium homeostasis and bone metabolism is well known. In recent years it has been recognized that in addition to the traditional functions, vitamin D modulates a variety of processes such as host defense, inflammation and immunity. Epidemiological data indicate that low levels of vitamin D in serum are associated with impaired lung function and increased incidence of inflammatory diseases, infectious diseases and cancer. The authors studied the correlation among vitamin D levels, allergic inflammation, lung function and control of asthma and found a significant decrease of FeNO values (p= 0.0018) in children with vitamin D levels>30 ng/ml. These findings confirm that vitamin D plays a major role in bronchial inflammation.
authors.affiliation: Department of Women, Child and General and Special Surgery, Second University of Naples, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Miraglia Del Giudice
authors.affiliation: Department of Women, Child and General and Special Surgery, Second University of Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Allegorico
authors.affiliation: Department of Women, Child and General and Special Surgery, Second University of Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Grandone
authors.affiliation: Department of Women, Child and General and Special Surgery, Second University of Naples, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Galdo
authors.affiliation: Department of Pediatric Sciences, Unit of Pediatrics Genetics and Immunology University of Messina, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Cuppari
authors.affiliation: Department of Women, Child and General and Special Surgery, Second University of Naples, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Capasso
authors.affiliation: Department of Women, Child and General and Special Surgery, Second University of Naples, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Maiello