title: Regadenoson stress for myocardial perfusion imaging.
abstract: Noninvasive functional imaging plays a major role in the diagnosis of hemodynamically significant coronary artery disease (CAD) by means of the detection of abnormal myocardial perfusion. For this, cardiac stressors are essential as they induce hypoperfusion in the presence of flow-limiting coronary stenosis. Several pharmacological stressors are currently available and it is important that clinicians who are involved in the care and management of patients with CAD become familiar with their indications, contraindications and protocols. Among the primary coronary vasodilator agents, regadenoson is increasingly used as the default stressor or as an alternative to other modalities of stress. This article provides an updated review of regadenoson stress for the assessment of patients with suspected or known CAD and describes its pharmacological properties, stress protocol, efficacy and safety profile.
authors.affiliation: Nuclear Medicine Department, Royal Brompton Hospital, London, SW3 6NP, UK.|Harefield Hospital, Hill End Road, Harefield, Middlesex, UB9 6JH, UK.
authors.forename: Eliana
authors.initials: E
authors.lastname: Reyes
mesh_terms: D058908:Adenosine A2 Receptor Agonists / Q000494:pharmacology*; D003324:Coronary Artery Disease / Q000175:diagnosis*; D006334:Heart Function Tests; D006801:Humans; D055414:Myocardial Perfusion Imaging / Q000379:methods*; D011687:Purines / Q000494:pharmacology*; D011720:Pyrazoles / Q000494:pharmacology*; D014665:Vasodilator Agents / Q000494:pharmacology
chemical_list: D058908:Adenosine A2 Receptor Agonists; D011687:Purines; D011720:Pyrazoles; D014665:Vasodilator Agents; C430916:regadenoson
keywords: coronary artery disease; myocardial perfusion imaging; regadenoson