title: Clinical Evaluation of the Hemodynamic Effects of the High-Flow Nasal Cannula Therapy on the Fontan Circulation.
abstract: High-flow nasal cannula (HFNC) therapy supports respiratory effort with a minimal elevation in airway pressure. We examined hemodynamic effects of HFNC therapy in a 10-year-old girl with Fontan circulation, in which positive airway pressure has deleterious hemodynamic effects. The HFNC therapy at 30 L/min improved oxygenation without an increase in central venous pressure. It also reduced heart rate, and systemic and pulmonary vascular resistance, and increased cardiac output. In addition, the HFNC therapy improved the cerebral circulation measured by near-infrared spectroscopy. Thus, HFNC therapy may be a potentially useful noninvasive ventilation modality, particularly for patients with Fontan circulation.
authors.affiliation: Department of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: Seiko
authors.initials: S
authors.lastname: Kuwata
authors.affiliation: Department of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: Clara
authors.initials: C
authors.lastname: Kurishima
authors.affiliation: Department of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: JeongHye
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Iwamoto
authors.affiliation: Department of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Saiki
authors.affiliation: Department of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Ishido
authors.affiliation: Department of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Masutani
authors.affiliation: Department of Pediatric Cardiology, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Senzaki
keywords: fontan; ventilation