title: Male breast carcinoma: radiotherapy contributed to favorable local control in two cases and related literature review.
abstract: Male breast carcinoma (MBC) is rarely encountered in clinical practice. Due to its paucity, our knowledge of MBC only rely on small or single-institutional studies and sporadic cases. The current guidelines for MBC are extrapolated from its female counterparts Rudlowski (Breast Care (Basel) 3(3):183-189, 2008). Nowadays, MBC is actively studied and viewed as a potentially different entity on the aspects of etiology, biological behavior and prognosis. Thus, special treatment strategy guidelines should be established for MBC. Additionally, advance in the systemic chemotherapy and hormonal therapy also contribute to the local control. The indication of radiotherapy need to be clarified and over-treatment should be avoided. Here we present two cases of MBC in which radiotherapy help to sustain a satisfactory disease free survival. Our cases will provide valuable experience for identifying the role of radiotherapy in MBC.
authors.affiliation: Department of Radiation Oncology, The First Hospital, Jilin University, 71 Xinmin Street, 130021, Changchun, China. liumin602822@163.com.
authors.forename: Min
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department of Radiation Oncology, The First Hospital, Jilin University, 71 Xinmin Street, 130021, Changchun, China. qiangwang1993@163.com.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Hand Surgery, The First Hospital, Jilin University, 71 Xinmin Street, 130021, Changchun, China. binliu1972@126.com.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Radiation Oncology, The First Hospital, Jilin University, 71 Xinmin Street, 130021, Changchun, China. chaoge198310@163.com.
authors.forename: Ling
authors.initials: L
authors.lastname: Gao
authors.affiliation: Department of Breast Surgery, The First Hospital, Jilin University, 71 Xinmin Street, 130021, Changchun, China. temuer2004@163.com.
authors.forename: Di
authors.initials: D
authors.lastname: Wu
authors.affiliation: Department of Radiation Oncology, The First Hospital, Jilin University, 71 Xinmin Street, 130021, Changchun, China. shuoyang1991@126.com.
authors.forename: Shuo
authors.initials: S
authors.lastname: Yang
authors.affiliation: Department of Radiation Oncology, The First Hospital, Jilin University, 71 Xinmin Street, 130021, Changchun, China. bailong3385@163.com.
authors.forename: Bailong
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Radiation Oncology, The First Hospital, Jilin University, 71 Xinmin Street, 130021, Changchun, China. lijie200461@126.com.
authors.forename: Lihua
authors.initials: L
authors.lastname: Dong
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018567:Breast Neoplasms, Male / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D008297:Male; D008408:Mastectomy; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D016896:Treatment Outcome