title: Alkaloid synthesis using chiral secondary amine organocatalysts.
abstract: Over the last decade, several excellent enantioselective total syntheses of important alkaloids using asymmetric reactions mediated by chiral secondary amine organocatalysts as a key step have been accomplished. This perspective article examines the full strategies of these alkaloid syntheses, especially the application of the organocatalytic reaction to construct the alkaloid scaffolds.
authors.affiliation: Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1, Kurokami, Chuo-ku, Kumamoto 860-8555, Japan. ishikawa@sci.kumamoto-u.ac.jp.
authors.forename: Hayato
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Shinya
authors.initials: S
authors.lastname: Shiomi
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure
chemical_list: D000470:Alkaloids; D000588:Amines