title: [The Relationship Between Level of End-Products of Tissue Glycation and Pulse Wave Velocity in Non-diabetic Patients With Cardiovascular Disease].
abstract: OBJECTIVE
  of the study was to assess the relationship between advanced glycation end-products measured by skin autofluorescence (AGEs) and pulse wave velocity (PWV) in non-diabetic patients with cardiovascular disease (CVD).
  
  
  METHODS
  Skin autofluorescence (AGE--reader, DiagnOptic) and PWV in humero-malleolar segment (PWVhm) were measured in 93 non-diabetic CVD patients (mean age 63.5 years): 28 with ischemic heart disease (IHD) and 65 without IHD from the group with moderate/high risk of development of cardiovascular complications.
  
  
  RESULTS
  Significant positive association was observed between AGEs and PWVhm (r = 0.31, p = 0.003). This correlation was found only in patients without IHD (r = 0.44, p < 0.0003). Positive association AGEs with of age (r = 0.52, p = 0.006) was observed irrespective of IHD. AGEs was not the significant determinant of PWVhm in multiple regression analysis.
  
  
  CONCLUSIONS
  Relationship between AGEs and PWVhm was found in non-diabetic moderate/high-risk patients. In contrast to age and systolic blood pressure AGEs was not the significant determinant of PWVhm.
authors.forename: F T
authors.initials: FT
authors.lastname: Ageev
authors.forename: M V
authors.initials: MV
authors.lastname: Vitsenia
authors.forename: M D
authors.initials: MD
authors.lastname: Smirnova
authors.forename: G V
authors.initials: GV
authors.lastname: Mihailov
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000378:metabolism / Q000503:physiopathology*; D003920:Diabetes Mellitus; D005260:Female; D017127:Glycation End Products, Advanced / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis / Q000379:methods*; D059289:Vascular Stiffness / Q000502:physiology*
chemical_list: D017127:Glycation End Products, Advanced