title: How effective is ustekinumab in controlling psoriatic arthritis?
abstract: Recently ustekinumab has been approved for the therapy of psoriatic arthritis (PsA). Some case series have been published reporting new onset of inflammatory arthritis in psoriasis patients treated with ustekinumab. In addition, flare of joint inflammation in PsA patients has also been reported. We describe a case series of seven patients affected by PsA who experienced either a worsening or a flare of inflammatory arthritis during treatment with ustekinumab.
authors.affiliation: Department of Clinical Dermatology, Center for the Study and Treatment of Psoriasis, San Gallicano Dermatologic Institute, IRCCS, Via Elio Chianesi 53, Rome, 00144, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Bonifati
authors.affiliation: Department of Clinical Dermatology, Center for the Study and Treatment of Psoriasis, San Gallicano Dermatologic Institute, IRCCS, Via Elio Chianesi 53, Rome, 00144, Italy.
authors.forename: Dario
authors.initials: D
authors.lastname: Graceffa
mesh_terms: D000328:Adult; D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects*; D015535:Arthritis, Psoriatic / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D003879:Dermatologic Agents / Q000009:adverse effects*; D018450:Disease Progression; D057915:Drug Substitution; D005260:Female; D006801:Humans; D007596:Joints / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome; D000069549:Ustekinumab / Q000009:adverse effects*
chemical_list: D018501:Antirheumatic Agents; D003879:Dermatologic Agents; D000069549:Ustekinumab
keywords: psoriasis; psoriatic arthritis; ustekinumab