title: Two new triterpenoid glycosides from the stems of Camellia oleifera Abel.
abstract: Two new oleanane-type triterpenoid glycosides, 3-O-β-D-xylopyranosyl-(1→2)-α-L-arabinopyranosyl-(1→3)-[β-D-glucuronopyranosyl-(1→2)]-β-D-glucuronopyranosyl-22α-angeloyloxyolean-12-ene-15α,16α,28-triol(1) and 3-O-β-D-xylopyranosyl-(1→2)-α-L-arabinopyranosyl-(1→3)-[β-D-glucuronopyranosyl-(1→2)]-β-D-glucuronopyranosyl-21β-acetyl-22α-angeloyloxyolean-12-ene-16α,28-diol (2) were isolated from the stems of Camellia oleifera Abel. Their structures were elucidated by means of spectroscopic methods and chemical evidence. The cytotoxic activities of compounds 1-2 were evaluated against five human tumour cell lines (HCT-8, BGC-823, A5049, and A2780). Compounds 1-2 showed cytotoxic activity against five human cancer cell lines, with IC50 values ranging from 3.15 to 7.32 μM.
authors.affiliation: a Jiangxi Provincial Institute for Drug Control, Jiangxi Provincial Engineering Research Center for Drug and Medical Device Quality , Nanchang , P.R. China.|b Pharmaceutical Department of Nanchang University , Nanchang , P.R. China.
authors.forename: Qing-Wei
authors.initials: QW
authors.lastname: Yan
authors.affiliation: a Jiangxi Provincial Institute for Drug Control, Jiangxi Provincial Engineering Research Center for Drug and Medical Device Quality , Nanchang , P.R. China.
authors.forename: Hui-Zheng
authors.initials: HZ
authors.lastname: Fu
authors.affiliation: a Jiangxi Provincial Institute for Drug Control, Jiangxi Provincial Engineering Research Center for Drug and Medical Device Quality , Nanchang , P.R. China.
authors.forename: Yue-Hua
authors.initials: YH
authors.lastname: Luo
authors.affiliation: a Jiangxi Provincial Institute for Drug Control, Jiangxi Provincial Engineering Research Center for Drug and Medical Device Quality , Nanchang , P.R. China.
authors.forename: Guo-Ping
authors.initials: GP
authors.lastname: Zhou
authors.affiliation: c Drug Adverse Reaction Monitoring Center of Jiangxi , Nanchang , P.R. China.
authors.forename: Kai-Hua
authors.initials: KH
authors.lastname: Wan
authors.affiliation: a Jiangxi Provincial Institute for Drug Control, Jiangxi Provincial Engineering Research Center for Drug and Medical Device Quality , Nanchang , P.R. China.
authors.forename: Rui-Jian
authors.initials: RJ
authors.lastname: Zhong
mesh_terms: D028244:Camellia / Q000737:chemistry*; D045744:Cell Line, Tumor; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D018547:Plant Stems / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D006027:Glycosides; D014315:Triterpenes
keywords: Camellia oleifera Abel; Theaceae; triterpenoid glycosides