title: Hyperhomocysteinemia and high doses of nilotinib favor cardiovascular events in chronic phase Chronic Myelogenous Leukemia patients.
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite.
authors.forename: Gaëlle
authors.initials: G
authors.lastname: Fossard
authors.affiliation: Laboratory of biochemistry, Centre Hospitalier Lyon Sud, Pierre Bénite INSERM U1060, CarMeN Laboratory, Lyon 1 University, INRA 1235, Oullins.
authors.forename: Emilie
authors.initials: E
authors.lastname: Blond
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite.
authors.forename: Marie
authors.initials: M
authors.lastname: Balsat
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Morisset
authors.affiliation: Laboratory of Hematology, Hôpital Henri Mondor, Créteil Groupe Fi-LMC, Hôpital Haut Lévêque, Pessac, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Giraudier
authors.affiliation: Hematology department, Hôpital Pontchaillou, Rennes Groupe Fi-LMC, Hôpital Haut Lévêque, Pessac, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Escoffre-Barbe
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite.
authors.forename: Hélène
authors.initials: H
authors.lastname: Labussière-Wallet
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite.
authors.forename: Maël
authors.initials: M
authors.lastname: Heiblig
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite.
authors.forename: Arthur
authors.initials: A
authors.lastname: Bert
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite Groupe Fi-LMC, Hôpital Haut Lévêque, Pessac, France.
authors.forename: Madeleine
authors.initials: M
authors.lastname: Etienne
authors.affiliation: Laboratory of biochemistry, Centre Hospitalier Lyon Sud, Pierre Bénite INSERM U1060, CarMeN Laboratory, Lyon 1 University, INRA 1235, Oullins.
authors.forename: Jocelyne
authors.initials: J
authors.lastname: Drai
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite.
authors.forename: Mohamad
authors.initials: M
authors.lastname: Sobh
authors.affiliation: Laboratory of biochemistry, Hôpital Pellegrin, Bordeaux.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Redonnet-Vernhet
authors.affiliation: Internal medicine department, Centre Hospitalier Lyon Sud, Pierre Bénite.
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Lega
authors.affiliation: Département d'hématologie, Institut Bergonié, Bordeaux Groupe Fi-LMC, Hôpital Haut Lévêque, Pessac, France.
authors.forename: François-Xavier
authors.initials: FX
authors.lastname: Mahon
authors.affiliation: Département d'hématologie, Institut Bergonié, Bordeaux Groupe Fi-LMC, Hôpital Haut Lévêque, Pessac, France.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Etienne
authors.affiliation: Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite Inserm U1052, Centre de Recherche en Cancérologie de Lyon Groupe Fi-LMC, Hôpital Haut Lévêque, Pessac, France franck-emmanuel.nicolini@chu-lyon.fr.
authors.forename: Franck Emmanuel
authors.initials: FE
authors.lastname: Nicolini
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D008076:Cholesterol, HDL / Q000097:blood; D003324:Coronary Artery Disease / Q000097:blood / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D004334:Drug Administration Schedule; D005260:Female; D006710:Homocysteine / Q000097:blood; D006801:Humans; D020138:Hyperhomocysteinemia / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D000068877:Imatinib Mesylate / Q000627:therapeutic use*; D015466:Leukemia, Myeloid, Chronic-Phase / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011743:Pyrimidines / Q000008:administration & dosage / Q000009:adverse effects*; D012189:Retrospective Studies; D014280:Triglycerides / Q000097:blood
chemical_list: D000970:Antineoplastic Agents; D008076:Cholesterol, HDL; D011743:Pyrimidines; D014280:Triglycerides; D006710:Homocysteine; D000068877:Imatinib Mesylate; C498826:nilotinib
keywords: BCR-ABL; cardiovascular events; chronic phase CML; homocysteine; nilotinib