title: Live kidney donation from a person with haemophilia.
abstract: There are many documented cases of a person with haemophilia successfully receiving a solid organ transplant, including liver and kidney. However, there is no literature reporting live organ donation by a person with haemophilia. Presumably, this is because the associated risks of excessive bleeding, inhibitor development after a period of intensive treatment with factor replacement and the possibility of variant Creutzfeldt-Jakob disease transmission in those previously treated with blood products, are considered excessive. This case describes a 24-year-old man who was diagnosed with mild haemophilia A during his pretransplant work up as a potential live kidney donor to his sister. He then went on to successfully donate his kidney, without complications. To the best of our knowledge, this is the first description of a person with haemophilia being a living organ donor.
authors.affiliation: Department of Haematology, Belfast City Hospital, Belfast, UK.
authors.forename: Christopher
authors.initials: C
authors.lastname: McCauley
authors.affiliation: Regional Nephrology Unit, Belfast City Hospital, Belfast, UK.
authors.forename: Agnes
authors.initials: A
authors.lastname: Masengu
authors.affiliation: Regional Nephrology Unit, Belfast City Hospital, Belfast, UK.
authors.forename: Aisling E
authors.initials: AE
authors.lastname: Courtney
authors.affiliation: Haemophilia and Thrombosis Centre, Belfast City Hospital, Belfast, UK.
authors.forename: Gary
authors.initials: G
authors.lastname: Benson
mesh_terms: D000328:Adult; D003894:Deamino Arginine Vasopressin / Q000097:blood / Q000627:therapeutic use*; D005169:Factor VIII / Q000187:drug effects; D006467:Hemophilia A / Q000097:blood / Q000601:surgery*; D006490:Hemostatics / Q000097:blood / Q000627:therapeutic use; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D020858:Tissue and Organ Harvesting; D055815:Young Adult
chemical_list: D006490:Hemostatics; D005169:Factor VIII; D003894:Deamino Arginine Vasopressin