title: Gynecomastia With Atypical Ductal Hyperplasia and Ductal Carcinoma In Situ Associated With Invasive Breast Carcinoma in a Male Patient on Antiretroviral Therapy: A Case Report.
abstract: Breast carcinoma in males is rare although a 4-fold increased incidence is reported in HIV-infected men. Herein we report a case of invasive breast carcinoma in a HIV-positive man on antiretroviral therapy. The carcinoma was associated with features of florid gynecomastia, atypical ductal hyperplasia, ductal carcinoma in situ, and columnar cell change. This combination of morphological changes has not previously been reported in the context of male breast carcinoma and their etiopathological associations are discussed.
authors.affiliation: The Royal Oldham Hospital, Oldham, UK Hopital Pasteur, Nice, France johnnycoyne@doctors.org.uk.
authors.forename: John D
authors.initials: JD
authors.lastname: Coyne
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D018567:Breast Neoplasms, Male / Q000150:complications / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000150:complications / Q000473:pathology*; D006177:Gynecomastia / Q000209:etiology*; D015658:HIV Infections; D006801:Humans; D008297:Male
keywords: HIV; antiretroviral therapy; atypical ductal hyperplasia; ductal carcinoma in situ; gynecomastia; invasive ductal carcinoma