title: 6'6" United States Marine Seeks Treatment for Gynecomastia Only to Learn It Is All in His Head.
abstract: Growth Hormone (GH) excess is an uncommon cause of gynecomastia encountered in primary care. Adults with GH excess (acromegaly) have a 72% increase in mortality compared with the general population, which is reversible with early detection and intervention. Currently, however, the diagnosis of acromegaly is often delayed up to 12 years because of the subtle onset of symptoms. We present an active duty male diagnosed with acromegaly after presenting to his primary care provider with chronic gynecomastia. The most common cause of GH excess is a pituitary somatotroph adenoma; however, it is important to remember that magnetic resonance imaging of the pituitary does not distinguish between functioning and nonfunctioning tumors. Subsequently, the diagnosis of GH excess is based on biochemical studies, not imaging.
authors.affiliation: 1st Marine Division, 5th Regiment 2/4 Marines, 62 Area Regimental Aid Station, Camp Pendleton, CA 92055.
authors.forename: David B
authors.initials: DB
authors.lastname: Young
mesh_terms: D000172:Acromegaly / Q000209:etiology*; D003937:Diagnosis, Differential; D049912:Growth Hormone-Secreting Pituitary Adenoma / Q000150:complications* / Q000000981:diagnostic imaging; D006177:Gynecomastia / Q000000981:diagnostic imaging / Q000209:etiology*; D019382:Human Growth Hormone / Q000097:blood*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D008297:Male; D008889:Military Personnel; D055815:Young Adult
chemical_list: D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I