title: Antibiotic Treatment of Hidradenitis Suppurativa.
abstract: Although hidradenitis suppurativa (HS) is not primarily an infectious disease, antibiotics are widely used to treat HS. Recent microbiological data show that HS suppurating lesions are associated with a polymorphous anaerobic flora, including actinomycetes and milleri group streptococci, and can therefore be considered as polymicrobial soft tissue and skin infections. Analysis of the literature provides little information on the efficacy of antibiotics in HS but suggests a beneficial effect of certain antimicrobial treatments, depending on the clinical severity of the disease. Patients must be informed and should agree with the treatment strategy before starting antibiotic treatments.
authors.affiliation: Department of Clinical and Experimental Medicine, OU of Dermatology, Azienda Ospedaliera - University of Ferrara, Via Aldo Moro 8, Località Cona, Ferrara 44100, Italy. Electronic address: vincenzo.bettoli@gmail.com.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Bettoli
authors.affiliation: Department of Microbiology, INSERM UMR 1151, Team 11 Necker Enfants-Malades Hospital, 149, rue de Sèvres, Paris 75015, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Join-Lambert
authors.affiliation: Medical Center, Institut Pasteur, 25 rue du Dr Roux, Paris 75015, France.
authors.forename: Aude
authors.initials: A
authors.lastname: Nassif
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000627:therapeutic use; D002981:Clindamycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D000077727:Ertapenem; D024841:Fluoroquinolones / Q000627:therapeutic use; D017497:Hidradenitis Suppurativa / Q000188:drug therapy*; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D060046:Maintenance Chemotherapy; D008795:Metronidazole / Q000627:therapeutic use; D000077266:Moxifloxacin; D012074:Remission Induction; D012293:Rifampin / Q000627:therapeutic use; D047090:beta-Lactams / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D047090:beta-Lactams; D008795:Metronidazole; D002981:Clindamycin; D015378:Imipenem; D002443:Ceftriaxone; D000077727:Ertapenem; D000077266:Moxifloxacin; D012293:Rifampin
keywords: Acne inversa; Antibiotherapy; Antimicrobial resistance; Hidradenitis suppurativa; Microbiome-host disease