title: The First Observation of Domoic Acid in Plankton Net Samples from the Sea of Marmara, Turkey.
abstract: This study reports the first evidence of domoic acid (DA), an algal neurotoxin produced by the genus Pseudo-nitzschia, from plankton net samples collected in the Sea of Marmara in December, 2010 and February, 2011. DA concentrations of plankton net samples were analyzed by high-performance liquid chromatography (HPLC), using the fluorenylmethoxycarbonyl fluorescence derivatization technique (detection limit 0.2 ng DA). The biotoxin concentrations in samples from coastal waters varied between 0.96 and 5.25 µg DA/mL. We also investigated possible correlations between physicochemical parameters and DA concentration. The DA levels appear to be correlated negatively with silica and nitrite concentrations for both sampling periods. These data may be used to evaluate the probability of finding similar conditions in coastal waters of the Sea of Marmara in order to determine the potential risks to local aquaculture and fisheries.
authors.affiliation: Department of Physical Oceanography and Marine Biology, Institute of Marine Sciences and Management, Istanbul University, 34134, Vefa, Istanbul, Turkey. fuat.dursun@istanbul.edu.tr.
authors.forename: Fuat
authors.initials: F
authors.lastname: Dursun
authors.affiliation: Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Marmara University, Haydarpaşa, Istanbul, Turkey. tyurdun@marmara.edu.tr.
authors.forename: Türkan
authors.initials: T
authors.lastname: Yurdun
authors.affiliation: Department of Physical Oceanography and Marine Biology, Institute of Marine Sciences and Management, Istanbul University, 34134, Vefa, Istanbul, Turkey. su@istanbul.edu.tr.
authors.forename: Selma
authors.initials: S
authors.lastname: Ünlü
mesh_terms: D002851:Chromatography, High Pressure Liquid; D017377:Diatoms / Q000737:chemistry*; D057097:Harmful Algal Bloom; D007608:Kainic Acid / Q000031:analogs & derivatives* / Q000032:analysis; D009498:Neurotoxins; D010933:Plankton / Q000737:chemistry*; D012623:Seawater / Q000737:chemistry; D057096:Shellfish Poisoning; D014421:Turkey
chemical_list: D009498:Neurotoxins; C012301:domoic acid; D007608:Kainic Acid
keywords: Domoic acid; HPLC-FLD analysis; Sea of Marmara; Seawater