title: Taking Snapshots of Ciliary Signaling.
abstract: Although the primary cilium critically influences signaling in development and disease, the organelle's small size and the dynamic nature of signaling events have posed obstacles to dissecting critical mechanisms. Reporting in Developmental Cell, Mick and colleagues (2015) describe cilia-APEX as an approach to provide dynamic "snapshots" of the ciliary proteome.
authors.affiliation: Program in Molecular Therapeutics, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
authors.forename: Anna S
authors.initials: AS
authors.lastname: Nikonova
authors.affiliation: Program in Molecular Therapeutics, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. Electronic address: erica.golemis@fccc.edu.
authors.forename: Erica A
authors.initials: EA
authors.lastname: Golemis
mesh_terms: D000818:Animals; D060387:Ascorbate Peroxidases / Q000378:metabolism*; D002923:Cilia / Q000378:metabolism*; D004622:Embryo, Mammalian / Q000378:metabolism*; D005347:Fibroblasts / Q000378:metabolism*; D020543:Proteome / Q000032:analysis*; D040901:Proteomics / Q000379:methods*; D055213:Retinal Pigment Epithelium / Q000378:metabolism*
chemical_list: D020543:Proteome; D060387:Ascorbate Peroxidases