title: EXPERIMENTAL STUDY ON ASSESSING INTERNAL RADIOACTIVE CONTAMINANTS BY USE OF NASAL SWAB.
abstract: Nasal swab analysis is an effective method to provide valuable information for early and fast estimates of alpha radionuclide intakes and resultant doses. In this study, an inhalation environment was built by use of lead nitrate aerosol to simulate alpha radioactive aerosol inhalation. The result of exposure and swabbing experiments with guinea pigs shows that the lead smeared on nasal swabs represents ∼13 % of intake if samples are acquired within 90 min after exposure and declines over time with a half-time of 1.4 h. The results also indicate a decreasing swabbing efficiency with post-exposure time. This study could provide useful information for the method of nasal swab used in nuclear and radiological emergencies.
authors.affiliation: Department of Radiation Protection and Health Physics, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Yunlong
authors.initials: Y
authors.lastname: Ji
authors.affiliation: Department of Radiation Protection and Health Physics, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Pan
authors.affiliation: Department of Radiation Protection and Health Physics, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Decheng
authors.initials: D
authors.lastname: Qu
authors.affiliation: Department of Radiation Protection and Health Physics, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Ning
authors.affiliation: Department of Radiation Protection and Health Physics, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Hongmei
authors.initials: H
authors.lastname: Zhou
authors.affiliation: Department of Radiation Protection and Health Physics, Beijing Institute of Radiation Medicine, Beijing 100850, China yanggs@nic.bmi.ac.cn.
authors.forename: Guoshan
authors.initials: G
authors.lastname: Yang
mesh_terms: D000280:Administration, Inhalation; D000396:Air Pollutants, Radioactive / Q000032:analysis*; D000512:Alpha Particles; D000818:Animals; D006168:Guinea Pigs; D007854:Lead / Q000008:administration & dosage / Q000032:analysis*; D008297:Male; D009296:Nasal Cavity / Q000378:metabolism*; D009566:Nitrates / Q000008:administration & dosage / Q000032:analysis*; D011834:Radiation Monitoring / Q000379:methods*
chemical_list: D000396:Air Pollutants, Radioactive; D009566:Nitrates; D007854:Lead; C017461:lead nitrate