title: Molecular characterization of human Torque Teno virus.
abstract: The present study analyzed the presence of human Torque Teno virus (TTV) in hospitalized patients from different departments. In total, 378 serum specimens were collected from the patients (171 with cardiovascular disease, 192 with tumor and 15 with gastroenteritis) and analyzed by ELISA and nest-polymerase chain reaction (PCR) to detect the presence of TTV. The results showed that 64 specimens (17%) were TTV positive from detection with the human ELISA kit, and the patients aged <30 years have a higher prevalence. TTV in males was more common than in female patients. In addition, nest-PCR was used to detect TTV within different phylogenetic groups among the 64 specimens, and the results showed that groups 1 (TA278 strain), 4 (KC009) and 5 (CT39) were much more prevalent than groups 2 (PMV isolate) and 3 (11 genotypes) in the different departmental patients.
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Youping
authors.initials: Y
authors.lastname: Wei
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Minyang
authors.initials: M
authors.lastname: Chen
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Xia
authors.initials: X
authors.lastname: Yang
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Liming
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Lihua
authors.initials: L
authors.lastname: Rao
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Feifang
authors.initials: F
authors.lastname: Yuan
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Yangqin
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Gong
authors.affiliation: Nanchang Hospital of Integrated Traditional Chinese and Western Medicine, Nanchang, Jiangxi 330003, P.R. China.
authors.forename: Lianping
authors.initials: L
authors.lastname: Li
keywords: ELISA; Torque Teno virus; human; polymerase chain reaction