title: Laparoscopic and Open Resection of Gastrointestinal Stromal Tumors of the Stomach.
abstract: BACKGROUND
  Laparoscopic resection has been reported as reasonable for patients with gastrointestinal stromal tumors (GISTs). In this study, we report the feasibility of the laparoscopic approach for GIST of the stomach. We also discuss the laparoscopic approach for GIST larger than 5 cm, which is reported to be difficult to treat by laparoscopic surgery.
  
  
  METHODS
  We retrospectively reviewed 22 patients with GIST of the stomach resected by laparoscopic or open procedures between January 2006 and February 2014.
  
  
  RESULTS
  Laparoscopic resections were performed in 9 patients and open resections in 13 patients. Curative resections with negative resection margins were successfully completed for all patients. Although the size of the tumors was greater in open surgery cases than in laparoscopic patients (P = 0.03), the loss of blood was lower and the hospital stay was shorter in laparoscopic cases (P = 0.01 and 0.003, respectively). Laparoscopic resection was performed for 2 patients with GISTs larger than 5 cm. Both were located at greater curvature, and curatively resected without any complications or recurrence.
  
  
  CONCLUSIONS
  Our experience suggests that laparoscopic surgery for GISTs of the stomach, including those larger than 5 cm, may be feasible after careful deliberation of its indications. Laparoscopic resection for GIST was associated with lower loss of blood and shorter hospital stay in comparison with open resection.
authors.forename: Ryota
authors.initials: R
authors.lastname: Nakanishi
authors.forename: Ikuo
authors.initials: I
authors.lastname: Takahashi
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Kajiwara
authors.forename: Takashi
authors.initials: T
authors.lastname: Motomura
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Fujinaka
authors.forename: Shin-ichiro
authors.initials: S
authors.lastname: Maehara
authors.forename: Takuya
authors.initials: T
authors.lastname: Honbo
authors.forename: Yuji
authors.initials: Y
authors.lastname: Soejima
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishizaki
mesh_terms: D000368:Aged; D005743:Gastrectomy; D046152:Gastrointestinal Stromal Tumors / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome