title: Functional MR Imaging Techniques in Oncology in the Era of Personalized Medicine.
abstract: DW and DCE MR imaging contribute significantly to diagnosis, treatment planning, response assessment, and prognosis in personalized cancer medicine. Nevertheless, the need for further standardization of these techniques needs to be addressed. Whole-body DW MR imaging is an exciting field; however, future studies need to investigate in more depth the biologic significance of the findings depicted, their prognostic relevance, and cost-effectiveness in comparison with MDCT and PET/CT. New MR imaging probes, such as targeted or activatable contrast agents and dynamic nuclear hyperpolarization, show great promise to further improve the care of patients with cancer in the near future.
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Clinic of Radiology and Nuclear Medicine, University of Basel Hospital, Petersgraben 4, Basel 4031, Switzerland. Electronic address: matthias.benz@usb.ch.
authors.forename: Matthias R
authors.initials: MR
authors.lastname: Benz
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
authors.forename: Hebert Alberto
authors.initials: HA
authors.lastname: Vargas
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
authors.forename: Evis
authors.initials: E
authors.lastname: Sala
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000639:trends*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008495:Medical Oncology / Q000639:trends; D057054:Molecular Imaging / Q000639:trends*; D009369:Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D057285:Precision Medicine / Q000639:trends*
chemical_list: D014408:Biomarkers, Tumor
keywords: DCE; DNP; DWI; Hepatobiliary contrast agent; MRS; SPIO