title: An overlooked parameter in coronary slow flow phenomenon: whole blood viscosity.
abstract: OBJECTIVE
  We aimed to assess the relationship between coronary slow flow phenomenon (CSFP) and whole blood viscosity (WBV).
  
  
  METHODS
  Two hundred patients with CSFP and 200 subjects with normal coronary arteries as control group were enrolled. WBV was calculated from hematocrit and plasma protein concentration at low shear rate (LSR) (0.5 s(-1)) and high shear rate (HSR) (208 s(-1)) by a validated equation.
  
  
  RESULTS
  CSFP patients had significantly higher WBV for LSR and HSR. The mean corrected TIMI frame count was highest in the highest tertile group for both shear rates. Corrected TIMI frame count revealed a significant relationship with WBV for LSR (r = 0.562) and HSR (r = 0.611). At multivariate analysis, WBV at LSR and HSR were independent predictors of CSFP.
  
  
  CONCLUSIONS
  WBV seemed to have a significant and an independent predictor of CSFP.
authors.affiliation: Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
authors.forename: Mehmet Serkan
authors.initials: MS
authors.lastname: Cetin
authors.affiliation: Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
authors.forename: Elif Hande
authors.initials: EH
authors.lastname: Ozcan Cetin
authors.affiliation: Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Canpolat
authors.affiliation: Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
authors.forename: Selahattin
authors.initials: S
authors.lastname: Aydın
authors.affiliation: Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temizhan
authors.affiliation: Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Topaloglu
authors.affiliation: Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
authors.forename: Dursun
authors.initials: D
authors.lastname: Aras
authors.affiliation: Turkey Yuksek Ihtisas Education & Research Hospital, Cardiology Clinic, Ankara, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Aydogdu
mesh_terms: D001809:Blood Viscosity; D003326:Coronary Circulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000150:complications; D054318:No-Reflow Phenomenon / Q000097:blood*; D012372:ROC Curve; D033081:Shear Strength; D013927:Thrombosis / Q000097:blood / Q000150:complications
keywords: TIMI frame count; coronary slow flow phenomenon; shear rate; whole blood viscosity