title: [The use of metabolomics in medicine - some examples of oncological and metabolic diseases].
abstract: Metabolomics is a new field of medicine focused on examining and analyzing metabolites produced in biological cells. Biological fluids primarily used in this method include: plasma, cerebrospinal fluid, saliva and urine. The most common methods of evaluating the composition involve nuclear magnetic resonance (NMR) and magnetic resonance (MR) with addition of gas chromatography (GC-MS) or liquid chromatography (LC-MS). Metabolomics is used in a wide variety of medicine disciplines. The variability of biochemical processes in tumor cells in comparison to normal cells is the starting point of such studies. The metabolomic changes are observed not only in solid tumors, like the mammary tumor, ovarian cancer, prostate cancer but also in tumors of the hematopoietic and lymphoid tissues. Nowadays, the aim of studies is to find biomarkers which would help to diagnose a disease quickly, assess its progression, and implement effective treatment. Metabolomics is also widely applied in metabolic diseases, mainly the diabetes. The list of examined metabolites gives promising chances for a successful prognosis, diagnosis and comprehensive monitoring of the progression of this civilization disease. The development of metabolomics will also contribute to the individualization of treatment, proper drugs adjustment, which will make a therapy more successful, cause less side effects and improve the quality of patient's life.
authors.affiliation: Studenckie Koło Naukowe Endokrynologii, Hematologii i Onkologii przy Zakładzie Podstaw Nauk Medycznych Uniwersytetu Medycznego im. Piastów Śląskich we Wrocławiu.
authors.forename: Dominika
authors.initials: D
authors.lastname: Zimny
authors.affiliation: Studenckie Koło Naukowe Endokrynologii, Hematologii i Onkologii przy Zakładzie Podstaw Nauk Medycznych Uniwersytetu Medycznego im. Piastów Śląskich we Wrocławiu.
authors.forename: Marta
authors.initials: M
authors.lastname: Szatkowska
authors.affiliation: Studenckie Koło Naukowe Endokrynologii, Hematologii i Onkologii przy Zakładzie Podstaw Nauk Medycznych Uniwersytetu Medycznego im. Piastów Śląskich we Wrocławiu.
authors.forename: Joanna
authors.initials: J
authors.lastname: Połubok
authors.affiliation: Studenckie Koło Naukowe Endokrynologii, Hematologii i Onkologii przy Zakładzie Podstaw Nauk Medycznych Uniwersytetu Medycznego im. Piastów Śląskich we Wrocławiu.
authors.forename: Julian
authors.initials: J
authors.lastname: Maciaszek
authors.affiliation: Studenckie Koło Naukowe Endokrynologii, Hematologii i Onkologii przy Zakładzie Podstaw Nauk Medycznych Uniwersytetu Medycznego im. Piastów Śląskich we Wrocławiu.
authors.forename: Mikołaj
authors.initials: M
authors.lastname: Machaj
authors.affiliation: Zakład Podstaw Nauk Medycznych Uniwersytetu Medycznego im. Piastów Śląskich we Wrocławiu.
authors.forename: Ewa
authors.initials: E
authors.lastname: Barg
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000378:metabolism*; D055432:Metabolomics; D009369:Neoplasms / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor
keywords: metabolites type 1 diabetes; metabolomics; tumor biomarkers NMR spectroscopy