title: Fever, Dry Cough and Exertional Dyspnea: Pulmonary Lymphomatoid Granulomatosis Masquerading as Pneumonia, Granulomatosis with Polyangiitis and Infectious Mononucleosis.
abstract: Lymphomatoid granulomatosis (LYG) is a rare Epstein-Barr virus-associated lymphoproliferative disorder. The disease lacks specific clinical and radiological manifestations, which may delay a definitive diagnosis. We report the case of a 39-year-old man with pulmonary LYG who presented to a hospital after experiencing three months of fever, weight loss, dry cough and exertional dyspnea. He was initially misdiagnosed with pneumonia, granulomatosis with polyangiitis and infectious mononucleosis due to the non-specific manifestations of the disease. We herein present the clinical and radiological characteristics of this case and discuss the procedure for pathological diagnosis, which will likely help clinicians in making a timely definitive diagnosis of this disease.
authors.affiliation: Department of Medicine, Beijing You An Hospital, Capital Medical University, Beijing Institute of Hepatology, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Xu
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.forename: Bishi
authors.initials: B
authors.lastname: Wang
authors.forename: Hongwei
authors.initials: H
authors.lastname: Zhang
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.forename: Ronghua
authors.initials: R
authors.lastname: Jin
authors.forename: Yulin
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000328:Adult; D003371:Cough / Q000209:etiology; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000209:etiology; D005334:Fever / Q000209:etiology; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D007244:Infectious Mononucleosis / Q000175:diagnosis; D008230:Lymphomatoid Granulomatosis / Q000175:diagnosis* / Q000473:pathology*; D008297:Male; D011014:Pneumonia / Q000209:etiology