title: Microsurgical treatment of patients with refractory epilepsy and mesial temporal cavernous malformations: Clinical experience of a tertiary epilepsy center.
abstract: BACKGROUND
  Mesiotemporal cavernous malformation can occur in 10-20% of patients with cerebral cavernomas and are frequently associated with refractory.
  
  
  METHODS
  A retrospective investigation was performed in the epilepsy clinic of a Brazilian tertiary referral epilepsy center, from January 2000 to March 2012.
  
  
  RESULTS
  A total of 21 patients were included in the study. Thirteen patients (62%) evolved to Engel I; 5 (24%) to Engel II, 2 (10%) to Engel III, and 1 (5%) to Engel IV. We observed that 10 (48%) patients with 12 years or less of epilepsy duration evolved to Engel I and 1 (5%) to Engel II; whereas from a total of 10 patients with epilepsy duration of more than 12 years, 3 (30%) evolved to Engel I and 7 (70%) to Engel II, III, or IV (P < 0.001 [bilateral]; P1 ≠ P2).
  
  
  CONCLUSIONS
  Postsurgical seizure outcome for temporal lobe epilepsy associated with mesiotemporal cavernomas is very satisfactory.
authors.affiliation: Department of Neurologic Sciences, Division of Neurosurgery, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São Paulo, Brazil.
authors.forename: Lucas Crociati
authors.initials: LC
authors.lastname: Meguins
authors.affiliation: Department of Neurologic Sciences, Division of Neurosurgery, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São Paulo, Brazil.
authors.forename: Rodrigo Antônio
authors.initials: RA
authors.lastname: Rocha da Cruz Adry
authors.affiliation: Department of Neurologic Sciences, Division of Neurosurgery, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São Paulo, Brazil.
authors.forename: Sebastião Carlos
authors.initials: SC
authors.lastname: da Silva Júnior
authors.affiliation: Department of Medicine, Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Carlos Umberto
authors.initials: CU
authors.lastname: Pereira
authors.affiliation: Department of Medical Sciences, Division of Neurosurgery, School of Medicine, University Nove de Julho, São Paulo, Brazil ; Department of Cerebrovascular and Skull Base Surgery, Center of Neurology and Neurosurgery Associates, Hospital Beneficência Portuguesa de São Paulo, São Paulo, Brazil.
authors.forename: Jean Gonçalves
authors.initials: JG
authors.lastname: de Oliveira
authors.affiliation: Department of Neurologic Sciences, Division of Neurosurgery, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São Paulo, Brazil.
authors.forename: Dionei Freitas
authors.initials: DF
authors.lastname: de Morais
authors.affiliation: Department of Psychiatry and Medical Psychology, Faculdade de Medicina de São José do Rio Preto, São Paulo, Brazil.
authors.forename: Gerardo Maria
authors.initials: GM
authors.lastname: de Araújo Filho
authors.affiliation: Department of Neurologic Sciences, Division of Neurology, Hospital de Base, Faculdade de Medicina de São José do Rio Preto, São Paulo, Brazil.
authors.forename: Lúcia Helena Neves
authors.initials: LH
authors.lastname: Marques
keywords: Cavernous malformations; mesiotemporal cavernous malformation; temporal lobe epilepsy