title: Radiological score for hemorrhage in the patients with portal hypertension.
abstract: OBJECTIVE
  To analyze the risk factors from radiological indices for hemorrhage in the patients with portal hypertension and weight risk factors.
  
  
  METHODS
  We retrospectively analyzed all cases of portal hypertension with hepatitis B from June 2008 to June 2014 in Nanjing Drum Tower hospital. Patients with hepatocellular carcinoma, portal vein thrombosis, or portal hypertension with other causes, such as autoimmune hepatitis, pancreatitis, or hematological diseases were excluded.
  
  
  RESULTS
  Ninety-eight patients were recruited and divided into hemorrhage and non-hemorrhage groups. There were no statistical differences in clinical indexes such as age, prothrombin time, serum albumin, serum creatinine, serum sodium, hemameba, and blood platelet count. However, the differences were statistically significant in total bilirubin, hemoglobin, and liver function with the p values of 0.023, 0.000, and 0.039 respectively. For radiological indices, hemorrhage was correlated with diameter of inferior mesenteric vein (P=0.0528), posterior gastric vein (P=0.0283), and esophageal varices scores (P=0.0221). Logistic procedure was used to construct the model with stepwise selection and finally inferior mesenteric vein, posterior gastric vein, esophageal varices, and short gastric vein were enrolled into the model. These veins were scored according to the diameters and the rates of hemorrhage were increased with the score. We then validated the model with 26 patents from July 2014 to December 2014. The AUC value was 0.8849 in ROC curves for this radiological model.
  
  
  CONCLUSIONS
  A risk model was constructed including inferior mesenteric vein, esophageal varices, posterior gastric vein, and short gastric vein. This radiological scoring model may be a valuable indicator for hemorrhage of portal hypertension.
authors.affiliation: Department of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Ge
authors.affiliation: Department of Digestive System, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
authors.forename: Ya-Juan
authors.initials: YJ
authors.lastname: Cao
authors.affiliation: Department of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
authors.forename: Min
authors.initials: M
authors.lastname: Xie
authors.affiliation: Department of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
authors.forename: Yi-Tao
authors.initials: YT
authors.lastname: Ding
authors.affiliation: Department of Digestive System, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
authors.forename: Ming
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of General Surgery, The Affiliated Drum Tower Hospital, Medical School of Nanjing University Nanjing 210008, Jiangsu Province, P. R. China.
authors.forename: De-Cai
authors.initials: DC
authors.lastname: Yu
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000150:complications*; D004932:Esophageal and Gastric Varices / Q000000981:diagnostic imaging; D005260:Female; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology*; D006509:Hepatitis B / Q000150:complications*; D006801:Humans; D006975:Hypertension, Portal / Q000000981:diagnostic imaging / Q000209:etiology*; D008113:Liver Neoplasms / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D008642:Mesenteric Veins / Q000000981:diagnostic imaging; D008875:Middle Aged; D011169:Portal Vein / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D012307:Risk Factors; D013162:Splenic Vein / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000150:complications; D055815:Young Adult
keywords: Portal hypertension; hemorrhage; radiological; risk assessment; risk factors