title: Advances in Medical Management of Early Stage and Advanced Breast Cancer: 2015.
abstract: Standard management of early stage and advanced breast cancer has been improved over the past few years by knowledge gained about the biology of the disease, results from a number of eagerly anticipated clinical trials and the development of novel agents that offer our patients options for improved outcomes or reduced toxicity or both. This review highlights recent major developments affecting the systemic therapy of breast cancer, broken down by clinically relevant patient subgroups and disease stage, and briefly discusses some of the ongoing controversies in the treatment of breast cancer and promising therapies on the horizon.
authors.affiliation: Program in Women׳s Oncology, Breast Health Center, Women and Infants Hospital of Rhode Island and Alpert Medical School of Brown University, Providence, RI; Department of Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Witherby
authors.affiliation: Program in Women׳s Oncology, Breast Health Center, Women and Infants Hospital of Rhode Island and Alpert Medical School of Brown University, Providence, RI.
authors.forename: Tina
authors.initials: T
authors.lastname: Rizack
authors.affiliation: Program in Women׳s Oncology, Breast Health Center, Women and Infants Hospital of Rhode Island and Alpert Medical School of Brown University, Providence, RI.
authors.forename: Bachir J
authors.initials: BJ
authors.lastname: Sakr
authors.affiliation: Program in Women׳s Oncology, Breast Health Center, Women and Infants Hospital of Rhode Island and Alpert Medical School of Brown University, Providence, RI.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Legare
authors.affiliation: Program in Women׳s Oncology, Breast Health Center, Women and Infants Hospital of Rhode Island and Alpert Medical School of Brown University, Providence, RI. Electronic address: wsikov@wihri.org.
authors.forename: William M
authors.initials: WM
authors.lastname: Sikov
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans
chemical_list: D000970:Antineoplastic Agents