title: Relapse of choroidal neovascularization in Bietti's crystalline retinopathy following anti-vascular endothelial growth factor therapy: A case report.
abstract: Choroidal neovascularization secondary to retinitis pigmentosa is rarely observed in clinical practice. The present study describes a case of atypical retinitis pigmentosa, crystalline retinal pigmentary degeneration, complicated by choroidal neovascularization (CNV) in a 26-year-old man presenting with blurred vision in the right eye. Heidelberg multimodality imaging was performed to achieve a confirmed diagnosis. Bevacizumab was injected once intravitreally. The 3-month follow-up included visualization of the lesion's regression with spectral domain optical coherence tomography (SD-OCT). However, at 3 months after the injection, the CNV reoccurred. To the best of our knowledge, this is the first time that a case of CNV secondary to retinitis pigmentosa, in which the diagnosis was confirmed via multimodality imaging and the therapeutic efficacy was evaluated by SD-OCT, has been reported in China.
authors.affiliation: Department of Ophthalmology, First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Rui
authors.initials: R
authors.lastname: Hua
authors.affiliation: Department of Ophthalmology, First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Kang
authors.initials: K
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Yuedong
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Department of Ophthalmology, Fourth Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Xinling
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, First Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chen
keywords: choroidal neovascularization; intravitreal bevacizumab; natural history; retinitis pigmentosa; spectral domain optical coherence tomography