title: What do we know about ground-glass opacity nodules in the lung?
abstract: Ground-glass opacity nodules (GGNs) in the lung attract clinical attention owing to their increasing incidence, unique natural course, and association with lung adenocarcinoma. A long and indolent course of a GGN makes it difficult to manage. Current extensive clinical, radiological, pathological, and genetic studies on GGNs have shed light on their pathogenesis and allowed development of a reliable strategy of management. The present editorial provides answers to clinical questions related to GGNs, such as the natural course, follow-up, prediction of growth, and resection techniques. Finally, I discuss the etiology of GGNs, which has not been fully elucidated so far.
authors.affiliation: 1 Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea ; 2 Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Choon-Taek
authors.initials: CT
authors.lastname: Lee
keywords: Ground-glass opacity nodules (GGNs); epidermal growth factor receptor (EGFR); growth; lung adenocarcinoma