title: Intravenous lipid emulsion and dexmedetomidine for treatment of feline permethrin intoxication: a report from 4 cases.
abstract: Four cases of feline permethrin intoxication are described. The cause of intoxication is the application of canine permethrin spot-on product (Advantix®, Bayer) by the owners. Principal clinical guidelines recommends the use of anticonvulsant drugs to treat seizures or neurological symptoms after initial stabilization and dermal decontamination. The use of lipid emulsion had an increasing interest in the last decade for treatment of toxicosis caused by lipophylic drugs as reported in human and in veterinary medical practices. All cats presented in this study, were treated with intravenous lipid emulsion (ILE) at variable dosages, and dexmedetomidine was also administered by intravenous way. No adverse reaction such as thrombophlebitis, overload circulation or others was noticed during and after administration of ILE. Dexmedetomidine was proved to be helpful in tranquillizing the cats. All cats were discharged in good condition faster than other cases treated without their use.
authors.affiliation: Department of Veterinary Science, Veterinary Teaching Hospital 'Mario Modenato', University of Pisa, via Livornese Lato Monte, 56122 S. Piero a Grado (Pisa), Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ceccherini
authors.affiliation: Department of Veterinary Science, Veterinary Teaching Hospital 'Mario Modenato', University of Pisa, via Livornese Lato Monte, 56122 S. Piero a Grado (Pisa), Italy.
authors.forename: F
authors.initials: F
authors.lastname: Perondi
authors.affiliation: Department of Veterinary Science, Veterinary Teaching Hospital 'Mario Modenato', University of Pisa, via Livornese Lato Monte, 56122 S. Piero a Grado (Pisa), Italy ; Department of Veterinary Science, Veterinary Teaching Hospital 'Mario Modenato', University of Pisa, via Livornese Lato Monte, 56122 S. Piero a Grado (Pisa), Italy.
authors.forename: I
authors.initials: I
authors.lastname: Lippi
authors.affiliation: Department of Veterinary Science, Veterinary Teaching Hospital 'Mario Modenato', University of Pisa, via Livornese Lato Monte, 56122 S. Piero a Grado (Pisa), Italy.
authors.forename: G
authors.initials: G
authors.lastname: Grazia
authors.affiliation: Department of Veterinary Science, Veterinary Teaching Hospital 'Mario Modenato', University of Pisa, via Livornese Lato Monte, 56122 S. Piero a Grado (Pisa), Italy.
authors.forename: V
authors.initials: V
authors.lastname: Marchetti
keywords: Cat; Dexmedetomidine; Intravenous lipid emulsion; Permethrin