title: Evaluation of abdominal circumference and salivary amylase activities after unsedated colonoscopy using carbon dioxide and air insufflations.
abstract: OBJECTIVE
  To assess and compare abdominal distention and stress in unsedated colonoscopy using carbon dioxide (CO2 ) and air insufflations.
  
  
  METHODS
  Two hundred and five patients underwent colonoscopic examinations without sedation using either CO2 or air insufflation. Abdominal circumference and salivary amylase (sAMY) activities before and 0 and 15 min after colonoscopy were measured by a nurse who was blinded to the grouping of the patients.
  
  
  RESULTS
  In all, 102 and 103 patients were randomly recruited in the CO2 and air insufflation groups, respectively. sAMY activities before and 0 and 15 min after colonoscopy were not significantly different between the two groups. Abdominal circumference measured immediately and 15 min after colonoscopy was significantly smaller in CO2 insufflation group than in the air insufflation group (81.2 cm vs 84.0 cm, and 79.7 cm vs 83.6 cm, respectively; P <0.05). The increasing ratio of abdominal circumference immediately after colonoscopy was not significantly different between the two groups; however, the ratio at 15 min after colonoscopy using CO2 insufflation was significantly lower than that in the air insufflation group (1.007 vs 1.028, P <0.001).
  
  
  CONCLUSIONS
  sAMY activities after unsedated colonoscopy using CO2 insufflation were not improved; however, CO2 insufflation decreases abdominal circumference after colonoscopy compared with air insufflation.
authors.affiliation: Department of Surgery, Gunma Chuo Hospital, Gunma.
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Kiriyama
authors.affiliation: Department of Surgery, Gunma Chuo Hospital, Gunma.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Naitoh
authors.affiliation: Department of Surgery, Gunma Chuo Hospital, Gunma.
authors.forename: Minoru
authors.initials: M
authors.lastname: Fukuchi
authors.affiliation: Department of Gastroenterology, Gunma Chuo Hospital, Gunma.
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Yuasa
authors.affiliation: Department of Gastroenterology, Gunma Chuo Hospital, Gunma.
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Horiuchi
authors.affiliation: Department of Surgery, Gunma Chuo Hospital, Gunma.
authors.forename: Takaharu
authors.initials: T
authors.lastname: Fukasawa
authors.affiliation: Department of Surgery, Gunma Chuo Hospital, Gunma.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Tabe
authors.affiliation: Department of Surgery, Gunma Chuo Hospital, Gunma.
authors.forename: Hayato
authors.initials: H
authors.lastname: Yamauchi
authors.affiliation: Department of Surgery, Gunma Chuo Hospital, Gunma.
authors.forename: Masaki
authors.initials: M
authors.lastname: Suzuki
authors.affiliation: Department of Surgery, Gunma Chuo Hospital, Gunma.
authors.forename: Tomonori
authors.initials: T
authors.lastname: Yoshida
authors.affiliation: Endoscopy Division, National Cancer Center Hospital, Tokyo.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Saito
authors.affiliation: Department of General Surgical Science, Graduate School of Medicine, Gunma University, Gunma, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kuwano
mesh_terms: D000005:Abdomen / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000388:Air; D000681:Amylases / Q000378:metabolism; D002245:Carbon Dioxide; D003113:Colonoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D007327:Insufflation / Q000009:adverse effects* / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012463:Saliva / Q000737:chemistry; D016037:Single-Blind Method; D055105:Waist Circumference
chemical_list: D002245:Carbon Dioxide; D000681:Amylases
keywords: abdominal circumference; abdominal distention; carbon dioxide; colonoscopy; salivary amylase