title: Multiple primary synchronous malignant tumors.
abstract: BACKGROUND
  Patients with primary multiple malignancies are progressively increasing due to prolonged survival of cancer patients and to the advances in diagnostic techniques and therapeutic options.
  
  
  METHODS
  Here we present a 66 year-old caucasian patient with four synchronous primary malignant tumors affecting the lung, oropharynx, large bowel and prostate gland, respectively, treated with multidisciplinary approach.
  
  
  CONCLUSIONS
  The increased incidence of multiple malignant tumors is a real challenge to the clinician and clinical attention should be made to avoid a misdiagnosis. In addition an early diagnosis is essential to achieve a radical treatment. We believe that the treatment modality should be carefully made and tailored on the individual patient suffering from this disease.
authors.affiliation: Department of General and Thoracic Surgery, Humanitas Research Hospital, via Manzoni 56 Rozzano, 20089, Milan, Italy. alberto.testori@humanitas.it.
authors.forename: Alberto
authors.initials: A
authors.lastname: Testori
authors.affiliation: Depatment of Surgery, University of Milan, Milan, Italy. ugo.cioffi@guest.unimi.it.
authors.forename: Ugo
authors.initials: U
authors.lastname: Cioffi
authors.affiliation: Depatment of Surgery, University of Milan, Milan, Italy. matilde.desimone@alice.it.
authors.forename: Matilde
authors.initials: M
authors.lastname: De Simone
authors.affiliation: Department of Pneumology, "G. Salvini" Hospital, Garbagnate Milanese, Milan, Italy. francesco_bini@hotmail.com.
authors.forename: Francesco
authors.initials: F
authors.lastname: Bini
authors.affiliation: Department of Pneumology, "G. Salvini" Hospital, Garbagnate Milanese, Milan, Italy. a.vaghi@aogarbagnate.lombardia.it.
authors.forename: Adriano
authors.initials: A
authors.lastname: Vaghi
authors.affiliation: Department of Diagnostic Radiology, Princess Elisabeth Hospital, Channel Islands, GY4-6UU, UK. alessandro.lemos@hotmail.com.
authors.forename: Alessandro A
authors.initials: AA
authors.lastname: Lemos
authors.affiliation: Laboratory of Clinical Informatics and Cardiovascular Imaging, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. michele.ciulla@unimi.it.|Cardiovascular Diseases Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy. michele.ciulla@unimi.it.
authors.forename: Michele M
authors.initials: MM
authors.lastname: Ciulla
authors.affiliation: Department of General and Thoracic Surgery, Humanitas Research Hospital, via Manzoni 56 Rozzano, 20089, Milan, Italy. marco.alloisio@humanitas.it.
authors.forename: Marco
authors.initials: M
authors.lastname: Alloisio
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology*