title: Supplemental vibrational force does not reduce pain experience during initial alignment with fixed orthodontic appliances: a multicenter randomized clinical trial.
abstract: This prospective randomized trial investigated the effect of supplemental vibrational force on orthodontic pain during alignment with fixed-appliances. Eighty-one subjects < 20 years-old undergoing extraction-based fixed-appliance treatment were randomly allocated to supplementary (20-minutes/day) use of an intra-oral vibrational device (AcceleDent(®)) (n = 29); an identical non-functional (sham) device (n = 25) or fixed-appliances only (n = 27). Each subject recorded pain intensity (using a 100-mm visual-analogue scale) and intake of oral analgesia in a questionnaire, following appliance-placement (T1) and first-adjustment (T2) for 1-week (immediately-after, 4, 24, 72-hours and at 1-week). Mean maximum-pain for the total sample was 72.96 mm [SD 21.59; 95%CI 68.19-77.74 mm] with no significant differences among groups (P = 0.282). Subjects taking analgesics reported slightly higher maximum-pain although this was not significant (P = 0.170). The effect of intervention was independent of analgesia (P = 0.883). At T1 and T2, a statistically and clinically significant increase in mean pain was seen at 4 and 24-hours, declining at 72-hours and becoming insignificant at 1-week. For mean alignment-rate, pain-intensity and use of analgesics, no significant differences existed between groups (P > 0.003). The only significant predictor for mean pain was time. Use of an AcceleDent vibrational device had no significant effect on orthodontic pain or analgesia consumption during initial alignment with fixed appliances.
authors.affiliation: King's College London Dental Institute, Department of Orthodontics, London SE19RT, UK.|Brighton and Sussex University Hospitals NHS Foundation Trust, Royal Alexandra Children's Hospital, Department of Orthodontics, Brighton BN25BE, UK.
authors.forename: Neil R
authors.initials: NR
authors.lastname: Woodhouse
authors.affiliation: East Kent Hospitals University NHS Foundation Trust, William Harvey Hospital, Department of Orthodontics, Ashford TN240LZ, UK.
authors.forename: Andrew T
authors.initials: AT
authors.lastname: DiBiase
authors.affiliation: University of Bonn, Department of Orthodontics and Department of Oral Technology, Bonn DE-53111, Germany.
authors.forename: Spyridon N
authors.initials: SN
authors.lastname: Papageorgiou
authors.affiliation: Brighton and Sussex University Hospitals NHS Foundation Trust, Royal Alexandra Children's Hospital, Department of Orthodontics, Brighton BN25BE, UK.
authors.forename: Nicola
authors.initials: N
authors.lastname: Johnson
authors.affiliation: Brighton and Sussex University Hospitals NHS Foundation Trust, Royal Alexandra Children's Hospital, Department of Orthodontics, Brighton BN25BE, UK.
authors.forename: Carmel
authors.initials: C
authors.lastname: Slipper
authors.affiliation: Brighton and Sussex University Hospitals NHS Foundation Trust, Royal Alexandra Children's Hospital, Department of Orthodontics, Brighton BN25BE, UK.
authors.forename: James
authors.initials: J
authors.lastname: Grant
authors.affiliation: King's College London Dental Institute, Department of Orthodontics, London SE19RT, UK.
authors.forename: Maryam
authors.initials: M
authors.lastname: Alsaleh
authors.affiliation: King's College London Dental Institute, Department of Orthodontics, London SE19RT, UK.
authors.forename: Martyn T
authors.initials: MT
authors.lastname: Cobourne
mesh_terms: D000293:Adolescent; D000700:Analgesics / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D016910:Orthodontic Brackets / Q000009:adverse effects*; D010146:Pain / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D010147:Pain Measurement / Q000295:instrumentation / Q000379:methods*; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014732:Vibration / Q000627:therapeutic use
chemical_list: D000700:Analgesics