title: A Genetically Modified Tobacco Mosaic Virus that can Produce Gold Nanoparticles from a Metal Salt Precursor.
abstract: We genetically modified tobacco mosaic virus (TMV) to surface display a characterized peptide with potent metal ion binding and reducing capacity (MBP TMV), and demonstrate that unlike wild type TMV, this construct can lead to the formation of discrete 10-40 nm gold nanoparticles when mixed with 3 mM potassium tetrachloroaurate. Using a variety of analytical physicochemical approaches it was found that these nanoparticles were crystalline in nature and stable. Given that the MBP TMV can produce metal nanomaterials in the absence of chemical reductants, it may have utility in the green production of metal nanomaterials.
authors.affiliation: Cell and Molecular Sciences, The James Hutton Institute Dundee, UK.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Love
authors.affiliation: A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University Moscow, Russia.
authors.forename: Valentine V
authors.initials: VV
authors.lastname: Makarov
authors.affiliation: Chemical Faculty, Lomonosov Moscow State University Moscow, Russia.
authors.forename: Olga V
authors.initials: OV
authors.lastname: Sinitsyna
authors.affiliation: Cell and Molecular Sciences, The James Hutton Institute Dundee, UK.
authors.forename: Jane
authors.initials: J
authors.lastname: Shaw
authors.affiliation: Physical Faculty, Lomonosov Moscow State University Moscow, Russia.
authors.forename: Igor V
authors.initials: IV
authors.lastname: Yaminsky
authors.affiliation: A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University Moscow, Russia.
authors.forename: Natalia O
authors.initials: NO
authors.lastname: Kalinina
authors.affiliation: Cell and Molecular Sciences, The James Hutton Institute Dundee, UK.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Taliansky
keywords: functional peptides; green synthesis; metal ion reduction; metal nanoparticles; plant virus