title: Influence of oral moisturizing jelly as a saliva substitute for the relief of xerostomia in elderly patients with hypertension and diabetes mellitus.
abstract: Dry mouth is common in elderly patients. However, the use of saliva substitute has been limited due to its inedibility. This study investigated the efficacy of oral moisturizing jelly (OMJ), a novel edible saliva substitute. A pre-post design was conducted in 118 elderly patients diagnosed with hypertension and/or diabetes mellitus. After using OMJ, signs and symptoms of dry mouth were compared with baseline data. The properties of saliva were compared between the OMJ use and non-use periods. The use of OMJ for 2 weeks significantly reduced symptoms of dry mouth, while the use for 1 month reduced the signs of xerostomia, prevented the decline of salivary pH(s) and improved buffering capacities. OMJ was equally effective in patients taking 1 to 2 and 3 to 7 medications. Furthermore, 65% of patients preferred OMJ over a commercial product. OMJ could be new edible saliva substitute for elderly patients suffering from dry mouth. Clinicaltrials.gov ID: NCT02317172.
authors.affiliation: Bureau of Dental Health, Department of Health, Ministry of Health, Nonthaburi, Thailand.
authors.forename: Supranee
authors.initials: S
authors.lastname: Dalodom
authors.affiliation: Faculty of Dentistry, Srinakharinwirot University, Bangkok, Thailand.
authors.forename: Aroonwan
authors.initials: A
authors.lastname: Lam-Ubol
authors.affiliation: Bureau of Dental Health, Department of Health, Ministry of Health, Nonthaburi, Thailand.
authors.forename: Sutha
authors.initials: S
authors.lastname: Jeanmaneechotechai
authors.affiliation: Lampang Provincial Public Health Office, Lampang, Thailand.
authors.forename: Lalana
authors.initials: L
authors.lastname: Takamfoo
authors.affiliation: Lampang Hospital, Lampang, Thailand.
authors.forename: Watanyoo
authors.initials: W
authors.lastname: Intachai
authors.affiliation: Jaehom Hospital, Lampang, Thailand.
authors.forename: Kochaporn
authors.initials: K
authors.lastname: Duangchada
authors.affiliation: The Dental Innovation Foundation under Royal Patronage, His Majesty the King's Dental Service Unit, Bangkok, Thailand.
authors.forename: Buakhao
authors.initials: B
authors.lastname: Hongsachum
authors.affiliation: The Dental Innovation Foundation under Royal Patronage, His Majesty the King's Dental Service Unit, Bangkok, Thailand; Food innovation and Packaging Center, Faculty of Agro-industry, Chiang Mai University, Chiang Mai, Thailand.
authors.forename: Panitnart
authors.initials: P
authors.lastname: Kanjanatiwat
authors.affiliation: Faculty of Dentistry, Srinakharinwirot University, Bangkok, Thailand.
authors.forename: Piamkamon
authors.initials: P
authors.lastname: Vacharotayangul
authors.affiliation: Institute of Nutrition, Mahidol University, Thailand. Electronic address: dunyaporn.tra@mahidol.ac.th.
authors.forename: Dunyaporn
authors.initials: D
authors.lastname: Trachootham
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D048909:Diabetes Complications / Q000150:complications*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D012464:Saliva, Artificial / Q000627:therapeutic use*; D016896:Treatment Outcome; D014987:Xerostomia / Q000188:drug therapy* / Q000209:etiology
chemical_list: D012464:Saliva, Artificial
keywords: Diabetes mellitus; Elderly patients; Hypertension; Poly medications; Saliva substitute; Xerostomia