title: Advance of the application of nano-controlled release system in ophthalmic drug delivery.
abstract: The ocular prescription application of nanometer materials are mainly concentrated in controlled release systems. Due to the unique properties of nanometer materials such as higher bioavailability and less side effects, it has great advantages in carrying ocular drugs of eye diseases compared with the traditional dosing method. As a result, nano-controlled release system has good application prospect in eye diseases. At present, a variety of different types of nano-controlled release systems have been used to enhance the efficiency of the ocular drugs including nanomicelles, nanoparticles, nanosuspensions, liposomes and dendrimers. In this article, the research progress and the application of nano-controlled release system in ophthalmic drug delivery are reviewed.
authors.affiliation: a Ophthalmology Department , The 2nd Teaching Hospital of Jilin University , Changchun , China.
authors.forename: Xuanzhong
authors.initials: X
authors.lastname: Wang
authors.affiliation: a Ophthalmology Department , The 2nd Teaching Hospital of Jilin University , Changchun , China.
authors.forename: Shurong
authors.initials: S
authors.lastname: Wang
authors.affiliation: a Ophthalmology Department , The 2nd Teaching Hospital of Jilin University , Changchun , China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D003692:Delayed-Action Preparations / Q000008:administration & dosage*; D050091:Dendrimers / Q000008:administration & dosage; D016503:Drug Delivery Systems / Q000379:methods; D005123:Eye / Q000187:drug effects*; D006801:Humans; D008081:Liposomes / Q000008:administration & dosage; D008823:Micelles; D053758:Nanoparticles / Q000008:administration & dosage*; D009883:Ophthalmic Solutions / Q000008:administration & dosage*
chemical_list: D003692:Delayed-Action Preparations; D050091:Dendrimers; D008081:Liposomes; D008823:Micelles; D009883:Ophthalmic Solutions
keywords: Drug controlled release system; drug therapy; eyes; nanometer materials