title: Metastatic Renal Cell Carcinoma Mimicking Trigeminal Schwannoma in a Patient Presenting with Trigeminal Neuralgia.
abstract: We present an unusual case of a metastatic renal cell carcinoma (RCC) mimicking trigeminal schwannoma. The patient, with no prior history of RCC, presented with clinical symptoms and imaging consistent with trigeminal neuralgia secondary to trigeminal schwannoma. Magnetic resonance imaging of the brain showed a large bilobed cystic/solid mass primarily in the cerebellopontine angle cistern, with extension into the left middle cranial fossa, Meckel cave, and left cavernous sinus. Following surgical excision, histopathology revealed the tumor to be an RCC infiltrating into the trigeminal nerve fascicles. Further imaging and investigation revealed widespread metastasis to the vertebral bodies and long bones. Metastatic RCC to the trigeminal nerve is rare. Despite the development of more effective treatment modalities, the prognosis of metastatic RCC remains poor. To our knowledge, this is the first reported case of RCC metastasizing to the trigeminal nerve fascicles.
authors.affiliation: Department of Neurosurgery, New York Medical College, Westchester, Valhalla, New York, United States.
authors.forename: Arthur
authors.initials: A
authors.lastname: Wang
authors.affiliation: Department of Pathology, New York Medical College, Westchester, Valhalla, New York, United States.
authors.forename: George
authors.initials: G
authors.lastname: Kleinman
authors.affiliation: Department of Neurosurgery, New York Medical College, Westchester, Valhalla, New York, United States.
authors.forename: Raj
authors.initials: R
authors.lastname: Murali
authors.affiliation: Department of Neurosurgery, New York Medical College, Westchester, Valhalla, New York, United States.
authors.forename: John
authors.initials: J
authors.lastname: Wainwright
authors.affiliation: Department of Neurosurgery, New York Medical College, Westchester, Valhalla, New York, United States.
authors.forename: Adesh
authors.initials: A
authors.lastname: Tandon
keywords: cerebellopontine angle; metastatic renal cancer; renal cell carcinoma; trigeminal neuralgia; trigeminal schwannoma