title: Hydrogel-based biosensors and sensing devices for drug delivery.
abstract: In the past 15years drug delivery devices have received added attention, not only as passive systems of drug delivery that respond to the needs of the health care provider or the patient but have an added advantage or an added characteristic of being triggered by an external process of recognition of a cause, a disease or an analyte that leads to a triggering mechanism for specific drug delivery. In this review, we will examine some of the pioneering work in this field, and speak on the use of biodegradable, environmentally-responsive hydrogels as sensing components in novel microscale devices.
authors.affiliation: Institute for Biomaterials, Drug Delivery and Regenerative Medicine, McKetta Department of Chemical Engineering, Department of Biomedical Engineering, and Division of Pharmaceutics, The University of Texas at Austin, Austin, TX 78712-1062, United States. Electronic address: peppas@che.utexas.edu.
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Peppas
authors.affiliation: Institute for Biomaterials, Drug Delivery and Regenerative Medicine, McKetta Department of Chemical Engineering, Department of Biomedical Engineering, and Division of Pharmaceutics, The University of Texas at Austin, Austin, TX 78712-1062, United States.
authors.forename: Diana Snelling
authors.initials: DS
authors.lastname: Van Blarcom
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods* / Q000639:trends; D016503:Drug Delivery Systems / Q000379:methods* / Q000639:trends; D006801:Humans; D020100:Hydrogels / Q000008:administration & dosage / Q000737:chemistry*
chemical_list: D020100:Hydrogels
keywords: Drug delivery; Environmentally-responsive hydrogels; Hydrogels