title: Assessment of Short-term Blood Pressure Variability in Patients With Ascending Aortic Dilatation.
abstract: BACKGROUND
  Blood pressure variability (BPV) is a novel parameter related to adverse cardiovascular findings and events, especially in hypertensive patients. The aim of the present study was to investigate the relationship between short-term BPV and ascending aortic dilatation (AAD).
  
  
  OBJECTIVE
  Hypertensive patients with AAD may exhibit higher short-term BPV compared to hypertensive patients with normal diameter ascending aorta and BPV may be correlated with aortic sizes.
  
  
  METHODS
  Seventy-six hypertensive patients with AAD and 181 hypertensive patients with a normal-diameter ascending aorta were retrospectively enrolled in the study. Clinical data, echocardiographic characteristics, and 24-hour ambulatory blood pressure monitoring characteristics were compared between the 2 groups. Standard deviation (SD) and Δ of BP were used as parameters of BPV.
  
  
  RESULTS
  Although 24-hour mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) were similar between the 2 groups, the SD of SBP and SD of DBP values were significantly higher in AAD patients (17.2 ± 6.8 vs 13.8 ± 3.5, P < 0.01; and 12.1 ± 5.1 vs 10.7 ± 3.1, P = 0.02, respectively). Daytime SD of SBP values were higher in AAD patients, whereas nighttime SD of SBP values did not differ between groups. In multivariate linear regression analysis, 24-hour SD of SBP, 24-hour Δ SBP, daytime SD of SBP, daytime Δ SBP, and left ventricular mass index were independently correlated with aortic size index.
  
  
  CONCLUSIONS
  Our study revealed higher levels of short-term BPV in hypertensive patients with AAD. This conclusion warrants further study.
authors.affiliation: Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
authors.forename: Mehmet Baran
authors.initials: MB
authors.lastname: Karataş
authors.affiliation: Department of Cardiology, Brigham and Women's Hospital, Boston, Massachusetts.
authors.forename: Göktürk
authors.initials: G
authors.lastname: İpek
authors.affiliation: Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
authors.forename: Yiğit
authors.initials: Y
authors.lastname: Çanga
authors.affiliation: Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
authors.forename: Barış
authors.initials: B
authors.lastname: Güngör
authors.affiliation: Department of Cardiology, Derince Training and Research Hospital, Kocaeli, Turkey.
authors.forename: Kazim Serhan
authors.initials: KS
authors.lastname: Özcan
authors.affiliation: Department of Cardiology, Sinop State Hospital, Sinop, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Arugaslan
authors.affiliation: Department of Cardiology, Ordu University, Ordu, Turkey.
authors.forename: Zeki Yüksel
authors.initials: ZY
authors.lastname: Günaydin
authors.affiliation: Department of Cardiology, Arnavutköy State Hospital, Istanbul, Turkey.
authors.forename: Gündüz
authors.initials: G
authors.lastname: Durmuş
authors.affiliation: Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
authors.forename: Tolga
authors.initials: T
authors.lastname: Onuk
authors.affiliation: Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
authors.forename: Koray
authors.initials: K
authors.lastname: Kalenderoğlu
authors.affiliation: Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
authors.forename: Evliya
authors.initials: E
authors.lastname: Akdeniz
authors.affiliation: Department of Cardiology, Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Bolca
mesh_terms: D000328:Adult; D001011:Aorta / Q000473:pathology; D001018:Aortic Diseases / Q000150:complications / Q000503:physiopathology*; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods; D004106:Dilatation; D004452:Echocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies