title: [DRUG INDUCED EXANTHEMA AND SEVERE CUTANEOUS DRUG REACTIONS].
abstract: Cutaneous adverse drug reactions (CADR) are delayed hypersensivities. Their clinical presentation and severity are very diverse ranging from the frequent and benign exanthemas to the rare but severe CADR involving deep organs in the case of drug reaction with eosinophilia and systemic symptoms (DRESS) or leading to skin bulla and epidermal detachment in toxic epidermal necrolysis. The main differential diagnoses are infections, especially viral ones, which could give clinical symptoms identical to those occurring in CADR.
authors.forename: Benoît
authors.initials: B
authors.lastname: Bensaïd
authors.forename: Laurence
authors.initials: L
authors.lastname: Valeyrie-Allanore
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Lebrun-Vignes
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Nicolas
mesh_terms: D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D063926:Drug Hypersensitivity Syndrome / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D005076:Exanthema / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D012720:Severity of Illness Index; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000209:etiology / Q000473:pathology