title: The Role of Mechanical Stress in Hidradenitis Suppurativa.
abstract: Mechanical stress can act as a possible trigger in the development of hidradenitis suppurativa (HS). The mechanical stress has been supported by (1) the special biomechanical conditions in the typically topographic areas of HS; (2) the indirect proof of similar findings in associated follicular occlusion diseases such as acne mechanica and pilonidal sinus disease, and in limb amputees after expression of mechanical forces; (3) pathohistologic, ultrasonography, and immunologic findings; and (4) overweight patients seem to be most susceptible to the effects of mechanical stress.
authors.affiliation: Department of Dermatology, Deventer Hospital, N. Bolkesteinlaan 75, Deventer 7416 SE, The Netherlands. Electronic address: jurrboer@home.nl.
authors.forename: Jurr
authors.initials: J
authors.lastname: Boer
authors.affiliation: Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, PO Box 80.082 Utrecht 3508 TB, The Netherlands.
authors.forename: Maiwand
authors.initials: M
authors.lastname: Nazary
authors.affiliation: Department of Dermatology, Roskilde Hospital, Kogevej 7-13, Roskilde DK-4000, Denmark.
authors.forename: Peter Theut
authors.initials: PT
authors.lastname: Riis
mesh_terms: D000672:Amputation Stumps / Q000473:pathology; D006201:Hair Diseases / Q000209:etiology / Q000473:pathology; D018859:Hair Follicle; D017497:Hidradenitis Suppurativa / Q000209:etiology* / Q000473:pathology; D006801:Humans; D050177:Overweight / Q000150:complications; D013314:Stress, Mechanical
keywords: Acne inversa; Acne mechanica; Follicular disease; Friction; Hidradenitis suppurativa; Limb amputees; Mechanical stress; Pilonidal sinus