title: Quality of life among people with multiple sclerosis: Replication of a three-factor prediction model.
abstract: BACKGROUND
  This article presents a replication of Rumrill, Roessler, and Fitzgerald's 2004 analysis of a three-factor model of the impact of multiple sclerosis (MS) on quality of life (QOL). The three factors in the original model included illness-related, employment-related, and psychosocial adjustment factors.
  
  
  OBJECTIVE
  To test hypothesized relationships between QOL and illness-related, employment-related, and psychosocial variables using data from a survey of the employment concerns of Americans with MS (N = 1,839).
  
  
  METHODS
  An ex post facto, multiple correlational design was employed incorporating correlational and multiple regression analyses.
  
  
  RESULTS
  QOL was positively related to educational level, employment status, job satisfaction, and job-match, and negatively related to number of symptoms, severity of symptoms, and perceived stress level. The three-factor model explained approximately 37 percent of the variance in QOL scores.
  
  
  CONCLUSIONS
  The results of this replication confirm the continuing value of the three-factor model for predicting the QOL of adults with MS, and demonstrate the importance of medical, mental health, and vocational rehabilitation interventions and services in promoting QOL.
authors.affiliation: University of Kentucky, Department of Early Childhood, Special Education, and Rehabilitation Counseling, Lexington, KY, USA.
authors.forename: Malachy
authors.initials: M
authors.lastname: Bishop
authors.affiliation: Center for Disability Studies, Kent State University, Kent, OH, USA.
authors.forename: Phillip D
authors.initials: PD
authors.lastname: Rumrill
authors.affiliation: Independent Rehabilitation Consultant, Fayetteville, Arkansas.
authors.forename: Richard T
authors.initials: RT
authors.lastname: Roessler
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D004522:Educational Status; D004651:Employment / Q000523:psychology; D005260:Female; D006801:Humans; D007588:Job Satisfaction; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D009103:Multiple Sclerosis / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index; D013315:Stress, Psychological / Q000209:etiology
keywords: Employment; chronic illness; mental health; psychosocial