title: Multifunctional Nanostructures for Tumor-Targeted Molecular Imaging and Photodynamic Therapy.
abstract: A multifunctional ICG-FA-PPD nanostructure is constructed by a facile self-assembly method through the negatively charged indocyanine green (ICG)- and positively charged folic acid-modified PEI-PEG-gadoteric acid (FA-PPD). The resulting ICG-FA-PPD is not only able to be used for targeting tumors, magnetic resonance imaging (MRI), and near-infrared imaging, but, more importantly, it enables photodynamic therapy for tumor.
authors.affiliation: Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.|University of the Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.affiliation: Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.|University of the Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Huihui
authors.initials: H
authors.lastname: Wang
authors.affiliation: Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.|University of the Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Han
authors.initials: H
authors.lastname: Liao
authors.affiliation: Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.|University of the Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Lv
authors.affiliation: Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.|University of the Chinese Academy of Sciences, Beijing, 100049, China.
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Song
authors.affiliation: Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Ma
authors.affiliation: Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.|National Engineering Research Center of Seafood, Liaoning Province Key Laboratory of Seafood Science and Technology, School of Food Science and Technology, Dalian Polytechnic University, Dalian, 116034, China.
authors.forename: Mingqian
authors.initials: M
authors.lastname: Tan
mesh_terms: D005492:Folic Acid / Q000737:chemistry; D006801:Humans; D007208:Indocyanine Green / Q000737:chemistry; D008279:Magnetic Resonance Imaging / Q000379:methods; D057054:Molecular Imaging / Q000379:methods; D049329:Nanostructures / Q000008:administration & dosage* / Q000737:chemistry*; D009369:Neoplasms / Q000628:therapy*; D010778:Photochemotherapy / Q000379:methods; D011092:Polyethylene Glycols / Q000737:chemistry; D011094:Polyethyleneimine / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: C544016:poly(ethylene glycol)-co-poly(ethyleneimine); D011092:Polyethylene Glycols; D011094:Polyethyleneimine; D005492:Folic Acid; D007208:Indocyanine Green
keywords: imaging; magnetic resonance imaging; multifunctional nanoprobes; near-infrared imaging; photodynamic therapy