title: Quality of life in patients with primary axillary hyperhidrosis before and after treatment with fractionated microneedle radiofrequency.
abstract: BACKGROUND
  Primary axillary hyperhidrosis (PAH) is a common condition with a great impact on the patient's quality of life (QOL). It is associated with serious social, emotional, and occupational distress. The aim of this study was to investigate the QOL in patients with PAH before and after treatment with fractionated microneedle radiofrequency (FMR).
  
  
  METHODS
  We evaluated 25 patients with severe PAH. Each patient had three sessions of FMR treatment using a novel applicator at 3-week intervals. The study was based on Dermatology Life Quality Index (DLQI) Questionnaires. Patients were evaluated at baseline and 3 months after the last session.
  
  
  RESULTS
  Our patients included 32% males and 68% females. The mean ± standard deviation (SD) age of subjects was 30.2 ± 6.27 years. The mean ± SD of the DLQI before and after treatment was 12.96 ± 5.93, and 4.29 ± 2.21, respectively. There was a statistically significant difference between the before and after intervention (P < 0.001). No major, permanent adverse effects were shown.
  
  
  CONCLUSIONS
  Treatment with FMR can improve the DLQI of patients with PAH.
authors.affiliation: Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Bahareh
authors.initials: B
authors.lastname: Abtahi-Naeini
authors.affiliation: Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Farahnaz Fatemi
authors.initials: FF
authors.lastname: Naeini
authors.affiliation: Psychosomatic Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Neda
authors.initials: N
authors.lastname: Adibi
authors.affiliation: Cancer Research Center, Students' Research Committee, Semnan University of Medical Sciences, Semnan, Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Pourazizi
keywords: Fractionated microneedle radiofrequency; primary axillary hyperhidrosis; quality of life