title: Congenital Mesoblastic Nephroma Presenting With Hematuria in a Neonate: A Case Report.
abstract: Congenital mesoblastic nephroma (CMN) is the most frequent renal neoplasm of newborns and young infants. Four cases presenting with hemorrhagic manifestations have been reported in the English literature (Hu et al, 2006; Bolande et al, 1967). We report the unusual clinical and radiographic findings of a 2-day-old neonate with hematuria secondary to a CMN. The first ultrasound was equivocal. Repeat ultrasound followed by magnetic resonance imaging confirmed the diagnosis. He underwent a right nephroureterectomy with histopathology revealing a cellular variant of CMN without classical translocation (t12:15). Neonates presenting with hematuria require close follow-up and serial imaging to rule out occult renal tumors. Classical translocation may not be demonstrable in all the cases.
authors.affiliation: Department of Paediatric Surgery and Urology, Children's Hospital at Westmead, Sydney, New South Wales, Australia. Electronic address: senthil.kamaraj@health.nsw.gov.au.
authors.forename: Senthil
authors.initials: S
authors.lastname: Kamaraj
authors.affiliation: Department of Pathology, Children's Hospital at Westmead, Sydney, New South Wales, Australia.
authors.forename: Susan
authors.initials: S
authors.lastname: Arbuckle
authors.affiliation: Department of Radiology, Children's Hospital at Westmead, Sydney, New South Wales, Australia.
authors.forename: Denise
authors.initials: D
authors.lastname: Warner
authors.affiliation: Department of Paediatric Surgery and Urology, Children's Hospital at Westmead, Sydney, New South Wales, Australia.
authors.forename: Grahame
authors.initials: G
authors.lastname: Smith
authors.affiliation: Department of Paediatric Surgery and Urology, Children's Hospital at Westmead, Sydney, New South Wales, Australia; Discipline of Paediatrics & Child Health, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Karpelowsky
mesh_terms: D006417:Hematuria / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007680:Kidney Neoplasms / Q000150:complications / Q000151:congenital* / Q000175:diagnosis*; D008297:Male; D018201:Nephroma, Mesoblastic / Q000150:complications / Q000151:congenital* / Q000175:diagnosis*