title: Three-dimensional stiffness of the carpal arch.
abstract: The carpal arch of the wrist is formed by irregularly shaped carpal bones interconnected by numerous ligaments, resulting in complex structural mechanics. The purpose of this study was to determine the three-dimensional stiffness characteristics of the carpal arch using displacement perturbations. It was hypothesized that the carpal arch would exhibit an anisotropic stiffness behavior with principal directions that are oblique to the conventional anatomical axes. Eight (n=8) cadavers were used in this study. For each specimen, the hamate was fixed to a custom stationary apparatus. An instrumented robot arm applied three-dimensional displacement perturbations to the ridge of trapezium and corresponding reaction forces were collected. The displacement-force data were used to determine a three-dimensional stiffness matrix using least squares fitting. Eigendecomposition of the stiffness matrix was used to identify the magnitudes and directions of the principal stiffness components. The carpal arch structure exhibited anisotropic stiffness behaviors with a maximum principal stiffness of 16.4±4.6N/mm that was significantly larger than the other principal components of 3.1±0.9 and 2.6±0.5N/mm (p<0.001). The principal direction of the maximum stiffness was pronated within the cross section of the carpal tunnel which is accounted for by the stiff transverse ligaments that tightly bind distal carpal arch. The minimal principal stiffness is attributed to the less constraining articulation between the trapezium and scaphoid. This study provides advanced characterization of the wrist׳s three-dimensional structural stiffness for improved insight into wrist biomechanics, stability, and function.
authors.affiliation: Hand Research Laboratory, Departments of Biomedical Engineering, Orthopaedic Surgery, and Physical Medicine and Rehabilitation, Cleveland Clinic, Cleveland, OH, USA; Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, OH, USA.
authors.forename: Joseph N
authors.initials: JN
authors.lastname: Gabra
authors.affiliation: Hand Research Laboratory, Departments of Biomedical Engineering, Orthopaedic Surgery, and Physical Medicine and Rehabilitation, Cleveland Clinic, Cleveland, OH, USA; Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, OH, USA. Electronic address: liz4@ccf.org.
authors.forename: Zong-Ming
authors.initials: ZM
authors.lastname: Li
mesh_terms: D000465:Algorithms; D002102:Cadaver; D002349:Carpal Tunnel Syndrome / Q000503:physiopathology; D006801:Humans; D016018:Least-Squares Analysis; D008022:Ligaments / Q000502:physiology; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D011403:Pronation; D021361:Scaphoid Bone / Q000502:physiology*; D051222:Trapezium Bone / Q000502:physiology*; D014953:Wrist / Q000502:physiology*; D014955:Wrist Joint / Q000502:physiology*
keywords: Carpal arch; Eigen decomposition; Principal component analysis; Stiffness matrix; Three-dimensional; Wrist