title: Undetermined Margins After Colonoscopic Polypectomy for Malignant Polyps: The Need for Radical Resection.
abstract: OBJECTIVE
  The aim of the present study was to analyze the clinicopathological features of patients with colorectal cancer (CRC) who underwent radical operation after malignant polyp removal by colonoscopic procedure.
  
  
  METHODS
  Between 2009 and 2013, radical colorectal resection was performed in 50 patients with CRC after colonoscopic polypectomy.
  
  
  RESULTS
  Nine cases (18%) had residual cancer. Lymph node (LN) metastasis was found in three cases (6.0%) and tumor deposit without LN metastasis (N1c) was found in two cases (4.0%). The indications for radical operation were an undetermined resection margin (23 cases), positive lateral margin (15 cases). Out of the nine cases with residual cancer, five cases had LN metastasis or tumor deposit without residual tumor in the main lesion. One-fourth of cases with an undetermined margin had residual cancer (six out of 23 cases), three of whom had stage III disease.
  
  
  CONCLUSIONS
  Undetermined margins may be considered as an indication for additional radical operation.
authors.affiliation: Department of Surgery, Colorectal Cancer Center, Konkuk University Medical Center, Seoul, Republic of Korea.
authors.forename: Eun-Joo
authors.initials: EJ
authors.lastname: Jung
authors.affiliation: Department of Surgery, Colorectal Cancer Center, Konkuk University Medical Center, Seoul, Republic of Korea.
authors.forename: Chun-Geun
authors.initials: CG
authors.lastname: Ryu
authors.affiliation: Department of Surgery, Colorectal Cancer Center, Konkuk University Medical Center, Seoul, Republic of Korea.
authors.forename: Jin Hee
authors.initials: JH
authors.lastname: Paik
authors.affiliation: Department of Surgery, Colorectal Cancer Center, Konkuk University Medical Center, Seoul, Republic of Korea Konkuk University School of Medicine, Seoul, Republic of Korea hwangcrc@kuh.ac.kr.
authors.forename: Dae-Yong
authors.initials: DY
authors.lastname: Hwang
mesh_terms: D000328:Adult; D000368:Aged; D003111:Colonic Polyps / Q000601:surgery*; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D018365:Neoplasm, Residual; D012189:Retrospective Studies; D055815:Young Adult
keywords: Colon polyp; colorectal neoplasm; endoscopic mucosal resection; polypectomy