title: [Recurrent hepatocellular carcinoma and adrenal metastasis without intrahepatic metastasis detected 22 years after hepatic resection: a case report].
abstract: A 55-year-old man presented with general malaise in May 2012. On reviewing his clinical records in 1989, we found that he had a hepatocellular carcinoma (HCC) in the left lobe, for which he had undergone left lobectomy in November 1989. However, there was no record of any follow-up examination from 1996 to 2011. Computed tomography in May 2012 revealed a right adrenal gland tumor measuring 8.5×6.5cm, which we treated by right adrenalectomy. Postoperative pathological examination showed this to be a metastasis of poorly differentiated HCC. To the best of our knowledge, no previous study has reported HCC recurrence such a long duration after HCC resection.
authors.affiliation: Social Insurance Tagawa Hospital.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Kawaguchi
authors.forename: Ichiro
authors.initials: I
authors.lastname: Miyajima
authors.forename: Ryouhei
authors.initials: R
authors.lastname: Kaji
authors.forename: Shigenari
authors.initials: S
authors.lastname: Sakakibara
authors.forename: Takashi
authors.initials: T
authors.lastname: Fushimi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Mori
authors.forename: Kensuke
authors.initials: K
authors.lastname: Miyahara
authors.forename: Ryuichiro
authors.initials: R
authors.lastname: Maekawa
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Yano
authors.forename: Takuji
authors.initials: T
authors.lastname: Torimura
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000556:secondary*; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013997:Time Factors