title: Bimodal immunoglobulin A gammopathy in a cat with feline myeloma-related disorders.
abstract: A 10-year-old female spayed mixed breed cat with a subcutaneous mass on the right hind limb was revealed with bimodal monoclonal gammopathy composed of IgA by immunoelectrophoresis and immunofixation. Approximately 1 month after referral, the cat died due to renal failure. Postmortem immunohistopathologic evaluation of the subcutaneous mass revealed neoplastic cell proliferation of plasma cells and giant myeloma cells. Neoplastic cells were also present in the liver and spleen. These results led to the diagnosis of a rare case of feline myeloma-related disorders with extramedullary plasmacytoma infiltrating in multiple locations. This report emphasizes the necessity to accumulate cases with similar clinicopathologic findings in the future.
authors.affiliation: Laboratory of Molecular Diagnostics and Therapeutics, Joint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi 753-8515, Japan.
authors.forename: Masaya
authors.initials: M
authors.lastname: Igase
authors.forename: Takako
authors.initials: T
authors.lastname: Shimokawa Miyama
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kambayashi
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Shimoyama
authors.forename: Hiroko
authors.initials: H
authors.lastname: Hiraoka
authors.forename: Yumi
authors.initials: Y
authors.lastname: Hirata
authors.forename: Miki
authors.initials: M
authors.lastname: Iwata
authors.forename: Kenji
authors.initials: K
authors.lastname: Baba
authors.forename: Takuya
authors.initials: T
authors.lastname: Mizuno
authors.forename: Masaru
authors.initials: M
authors.lastname: Okuda
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000276:immunology*; D002415:Cats; D005260:Female; D007070:Immunoglobulin A; D009101:Multiple Myeloma / Q000150:complications / Q000276:immunology / Q000662:veterinary*; D010265:Paraproteinemias / Q000209:etiology / Q000276:immunology / Q000662:veterinary*
chemical_list: D007070:Immunoglobulin A