title: Comparison of the transcutaneous bilirubinometers BiliCare and Minolta JM-103 in late preterm and term neonates.
abstract: OBJECTIVE
  To assess the agreement of transcutaneous bilirubin (TcB) measurement with the Bilicare™ System in comparison to TcB measured with JM-103™ and total serum bilirubin (TSB).
  
  
  METHODS
  Caucasian infants with gestational age ≥35 weeks with non-hemolytic jaundice received TcB measurement with both Bilicare™ and JM-103™ devices. TSB was also obtained in infants at risk of phototherapy.
  
  
  RESULTS
  We studied 458 infants measuring TcB with Bilicare™ and JM-103™, correlating the results and with TSB. The mean difference ± 2SD between Bilicare™ and JM-103™ TcB was 2.02 ± 4.46 mg/dL and decreased from 2.88 ± 3.17 to 1.20 ± 4.55, and to -0.95 ± 4.58 mg/dL at mild, moderate and high TcB values, respectively.
  
  
  CONCLUSIONS
  Bilicare™ and JM-103™ TcB measurements are well correlated, but Bilicare™ over-estimates TcB for mild and moderate values and under-estimates it for high values compared to JM-103™. This could increase the prescription of TSB measurements for less serious cases and decrease them in the most worrisome.
authors.affiliation: a Division of Neonatology , Careggi University Hospital of Florence , Florence , Italy .
authors.forename: Simone
authors.initials: S
authors.lastname: Pratesi
authors.affiliation: b Clinical Trials Coordinating Center, Istituto Toscano Tumori, Florence, Italy .|c Department of Human Pathology and Oncology , University of Florence , Florence , Italy , and.
authors.forename: Luca
authors.initials: L
authors.lastname: Boni
authors.affiliation: b Clinical Trials Coordinating Center, Istituto Toscano Tumori, Florence, Italy .|c Department of Human Pathology and Oncology , University of Florence , Florence , Italy , and.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Tofani
authors.affiliation: a Division of Neonatology , Careggi University Hospital of Florence , Florence , Italy .
authors.forename: Elettra
authors.initials: E
authors.lastname: Berti
authors.affiliation: a Division of Neonatology , Careggi University Hospital of Florence , Florence , Italy .
authors.forename: Sara
authors.initials: S
authors.lastname: Sollai
authors.affiliation: d Department of Neurosciences , Psychology, Drug Research and Children's Health, University of Florence , Florence , Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Dani
mesh_terms: D001663:Bilirubin / Q000032:analysis*; D019963:Clinical Chemistry Tests / Q000295:instrumentation; D006801:Humans; D051556:Hyperbilirubinemia, Neonatal / Q000175:diagnosis*; D007231:Infant, Newborn; D007234:Infant, Premature / Q000378:metabolism*; D015997:Neonatal Screening / Q000295:instrumentation* / Q000379:methods; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013053:Spectrophotometry / Q000379:methods
chemical_list: D001663:Bilirubin
keywords: Infant; jaundice; transcutaneous bilirubinometry