title: Sjögren SER: National registry of the Spanish Society of Rheumatology of patients with primary Sjögren syndrome: Objectives and methodology.
abstract: OBJECTIVE
  To describe the objectives and methods of the Spanish Society of Rheumatology primary Sjögren syndrome (pSS) registry (SJOGREN-SER) METHODS: This is a multicenter descriptive transversal study of a cohort of pSS patients fulfilling European/American consensus criteria collected from Rheumatology clinics all over Spain. Patients were included by randomisation from an anonymised list provided by every department. Data were collected by reviewing clinical records and an interviewing the patients. Two hundred and ninety eight variables were investigated: epidemiological, clinical, serological characteristics, treatments and complications. Informed consent was obtained and local ethics committees approved the study. Variables were analysed by descriptive statistical methods, using means, medians, and rates, with their deviations and interquartile ranges (p25-p75).
  
  
  RESULTS
  A total of 3 rheumatology departments participated in the registry. A total of 437 patients were included. And 95% of them were women, with a median age of 58. Median age at pSS 's diagnosis was 50 years. Dryness symptoms (95%) were the most frequent complaint and anti-Ro/SS-A were present in 94% of the cases. Only 27% of the patients fulfilled the new 2012 SICCA-ACR classification criteria.
  
  
  CONCLUSIONS
  SJOGREN-SER has been designed in order to characterize a representative pSS Spanish cohort, in clinical daily practice, to analyze the magnitude and distribution of its manifestations, activity, accumulated damage and therapeutic management of the disease. This will allow broadening the knowledge of this disease and plan strategies of action in pSS.
authors.affiliation: Servicio de Reumatología, Hospital Infanta Sofía, San Sebastián de los Reyes (Madrid), España. Electronic address: monfercas@yahoo.es.
authors.forename: Mónica
authors.initials: M
authors.lastname: Fernández Castro
authors.affiliation: Servicio de Reumatología, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, España.
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Andreu
authors.affiliation: Unidad de Investigación de la SER, España.
authors.forename: Carlos
authors.initials: C
authors.lastname: Sánchez-Piedra
authors.affiliation: Servicio de Reumatología, Hospital Marqués de Valdecilla, Santander, España.
authors.forename: Víctor
authors.initials: V
authors.lastname: Martínez Taboada
authors.affiliation: Servicio de Reumatología, Hospital Germans Trias i Pujol, Badalona, España.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Olivé
authors.affiliation: Servicio de Reumatología, Hospital Marina Baixa, Villajoyosa, España.
authors.forename: José
authors.initials: J
authors.lastname: Rosas
authors.affiliation: Unidad de Investigación de la SER, España.
authors.forename: Fernando
authors.initials: F
authors.lastname: Sánchez-Alonso
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012042:Registries; D012189:Retrospective Studies; D012219:Rheumatology; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D012955:Societies, Medical; D013030:Spain
keywords: Methodology; Metodología; Primary Sjögren syndrome; Registro; Registry; Síndrome de Sjogren primario