title: Influences of the steam sterilization on the properties of calcium phosphate porous bioceramics.
abstract: The influences of steam sterilization on the physicochemical properties of calcium phosphate (Ca-P) porous bioceramics, including β-tricalcium phosphate (β-TCP), biphasic calcium phosphate (BCP) and hydroxyapatite (HA) are investigated. After being steam sterilized in an autoclave (121 °C for 40 min), the porous bioceramics are dried and characterized. The steam sterilization has no obvious effects on the phase composition, thermal stability, pH value and dissolubility of β-TCP porous bioceramic, but changes its morphology and mechanical strength. Meanwhile, the steam sterilization leads to the significant changes of the morphology, phase composition, pH value and dissolubility of BCP porous bioceramic. The increase of dissolubility and mechanical strength, the decrease of pH value of the immersed solution and partial oriented growth of crystals are also observed in HA porous bioceramic after steam sterilization. These results indicate that the steam sterilization can result in different influences on the physicochemical properties of β-TCP, BCP and HA porous bioceramics, thus the application of the steam sterilization on the three kinds of Ca-P porous bioceramics should be considered carefully based on the above changed properties.
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, People's Republic of China.
authors.forename: Xiangfeng
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Opthalmology, West China Hospital of Sichuan University, Chengdu, 610061, People's Republic of China.
authors.forename: Bo
authors.initials: B
authors.lastname: Guo
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, People's Republic of China. xymzl2000@126.com.
authors.forename: Yumei
authors.initials: Y
authors.lastname: Xiao
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, People's Republic of China.
authors.forename: Tun
authors.initials: T
authors.lastname: Yuan
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, People's Republic of China.
authors.forename: Yujiang
authors.initials: Y
authors.lastname: Fan
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, People's Republic of China. zhangxd@scu.edu.cn.
authors.forename: Xingdong
authors.initials: X
authors.lastname: Zhang
mesh_terms: D001672:Biocompatible Materials; D002130:Calcium Phosphates / Q000737:chemistry*; D002516:Ceramics; D006863:Hydrogen-Ion Concentration; D008855:Microscopy, Electron, Scanning; D012995:Solubility; D013227:Steam
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D013227:Steam; C020243:calcium phosphate