title: The Microbiology of Hidradenitis Suppurativa.
abstract: Although the clinical presentation of Hidradenitis Suppurativa (HS) is strongly reminiscent of bacterial infection, the role of bacteria remains controversial. Studies have isolated an array of different bacterial specimens as well as biofilm formation in lesional HS skin. Consistent findings of Gram-positive cocci and -rods including Staphylococus aureus, Coagulase-negative staphylococci (CoNS) and Corynebacterium species (spp) in deep tissue samples have been demonstrated in HS. Although efficacy of antibiotics, i.e., rifampicin, clindamycin or tetracycline may support a microbial role in disease pathogenesis, the most often isolated bacterial specimens are commensal bacteria (CoNS).
authors.affiliation: Department of Dermatology, Roskilde Hospital, University of Copenhagen, Køgevej 7-13, Roskilde 4000, Denmark. Electronic address: hrin@regionsjaelland.dk.
authors.forename: Hans Christian
authors.initials: HC
authors.lastname: Ring
authors.affiliation: Department of Dermatology & Venereology, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Lennart
authors.initials: L
authors.lastname: Emtestam
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018441:Biofilms; D002981:Clindamycin / Q000627:therapeutic use; D003354:Corynebacterium Infections / Q000382:microbiology*; D017497:Hidradenitis Suppurativa / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D012293:Rifampin / Q000627:therapeutic use; D012867:Skin / Q000382:microbiology*; D013207:Staphylococcal Skin Infections / Q000382:microbiology*; D013211:Staphylococcus aureus; D013212:Staphylococcus epidermidis; D013752:Tetracycline / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin; D013752:Tetracycline; D012293:Rifampin
keywords: Acne inversa; Bacteria; Colonization; Hidradenitis suppurativa; Microbiology