title: Percutaneous computed tomography-guided lung biopsy of solitary nodular ground-glass opacity.
abstract: OBJECTIVE
  To evaluate the diagnostic performance and safety of percutaneous lung biopsy under computed tomography (CT)-fluoroscopic guidance for ground-glass opacity (GGO) lesions.
  
  
  METHODS
  Thirty-eight patients received core biopsy utilizing an automated cutting needle and were evaluated histologically.
  
  
  RESULTS
  Five patients had a bronchioloalveolar carcinoma, 3 patients had adenocarcinomas, 18 patients had pulmonary alveoli epithelial dysplasia, 1 patient had a large number of lymphocytes, and 11 patients had a small amount of fibrous connective tissue. Twenty-three lesions (23/38, 60.5%) were located in the upper lobes while 15 lesions (15/38, 39.5%) were located in the lower lobes. Twenty-five lesions (25/38, 65.8%) were located in the right lung while 13 lesions (13/38, 34.2%) were located in the left lung. Three patients had pneumothorax, appeared on CT images performed immediately after the biopsy. Four patients had mild parenchymal hemorrhage along the needle tract or within the lesion. No patient required additional therapy such as a blood transfusion, endotracheal intubation, or chest tube placement after the biopsy. None of the patients had serious complications.
  
  
  CONCLUSIONS
  Percutaneous CT-guided aspiration can be useful and safe diagnostic procedures for evaluating GGO nodules and a guidance to make a clinical decision for further patient management.
authors.forename: Yi-Feng
authors.initials: YF
authors.lastname: Zheng
authors.affiliation: Department of Interventional Radiology, Zhejiang Cancer Hospital, Hangzhou 310022, China.
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Jiang
authors.affiliation: Zhejiang Key Laboratory of Diagnosis and Treatment Technology Research on Chest Tumor (Lung, Esophagus), Zhejiang Cancer Hospital, Hangzhou 310022, China.
authors.forename: Wei-Min
authors.initials: WM
authors.lastname: Mao
authors.affiliation: Department of Respiration, Quzhou People's Hospital, Quzhou 324000, Zhejiang, China.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Han
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed