title: [Predictive factors for locally recurrent rectal cancer after primary curative surgery].
abstract: Local recurrence is a major clinical challenge after primary rectal cancer surgery. Although there is a possibility that R0 resection can be achieved, the outcome is still not favorable due to the low R0 resection rate and complexity of the surgery. Therefore prevention has a higher priority over treatment afterwards. As TME principle is accepted worldwide, the local recurrence rate has been reduced dramatically. And there are other factors associated with local recurrence including CRM, operation type, staging and PNI. Proper chemoradiotherapy may reduce the risk, however benefit always comes with side effect, therefore risk stratification is important.
authors.affiliation: Department of General Surgery, Ruijin Hospital,Shanghai Jiaotong University School of Medcine, Shanghai 200025, China. zhaorensurgeon@aliyun.com.
authors.forename: Haoji
authors.initials: H
authors.lastname: Gao
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.forename: Ren
authors.initials: R
authors.lastname: Zhao
mesh_terms: D059248:Chemoradiotherapy; D006801:Humans; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome