title: Management of recurrence after initial surgery for malignant pleural mesothelioma: a mini-review.
abstract: Recurrence after surgery in the multimodality therapy for malignant pleural mesothelioma is a common problem. As the majority of patients experience not only local but also distant metastases, a systemic treatment strategy in addition to local control measures remains necessary. Nevertheless, none of the chemotherapy regimens have achieved clinical success. Local management modalities such as stereotaxic treatments, cryoablation and redo surgery on the other hand have promising results, but provide palliative outcomes.
authors.affiliation: Thoracic Surgery Department, Faculty of Medicine, Acıbadem University, Acıbadem Maslak Hospital, Buyukdere Cad, 34457 Istanbul, Turkey.
authors.forename: Semih
authors.initials: S
authors.lastname: Halezeroğlu
authors.affiliation: Academic Thoracic Surgery, Department of Surgery & Medical Specialties, University of Catania, 95124 Catania, Italy.
authors.forename: Marcello
authors.initials: M
authors.lastname: Migliore
mesh_terms: D003131:Combined Modality Therapy / Q000379:methods; D019468:Disease Management; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000628:therapy*; D008654:Mesothelioma / Q000188:drug therapy* / Q000628:therapy*; D000086002:Mesothelioma, Malignant; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy* / Q000628:therapy*; D010997:Pleural Neoplasms / Q000188:drug therapy* / Q000628:therapy*
keywords: failure; mesothelioma; recurrence; surgery