title: Diagnostic Accuracy of Obstructive Airway Adult Test for Diagnosis of Obstructive Sleep Apnea.
abstract: BACKGROUND
  The gold standard for the diagnosis of Obstructive Sleep Apnea (OSA) is polysomnography, whose access is however reduced by costs and limited availability, so that additional diagnostic tests are needed.
  
  
  OBJECTIVE
  To analyze the diagnostic accuracy of the Obstructive Airway Adult Test (OAAT) compared to polysomnography for the diagnosis of OSA in adult patients.
  
  
  METHODS
  Ninety patients affected by OSA verified with polysomnography (AHI ≥ 5) and ten healthy patients, randomly selected, were included and all were interviewed by one blind examiner with OAAT questions.
  
  
  RESULTS
  The Spearman rho, evaluated to measure the correlation between OAAT and polysomnography, was 0.72 (p < 0.01). The area under the ROC curve (95% CI) was the parameter to evaluate the accuracy of the OAAT: it was 0.91 (0.81-1.00) for the diagnosis of OSA (AHI ≥ 5), 0.90 (0.82-0.98) for moderate OSA (AHI ≥ 15), and 0.84 (0.76-0.92) for severe OSA (AHI ≥ 30).
  
  
  CONCLUSIONS
  The OAAT has shown a high correlation with polysomnography and also a high diagnostic accuracy for the diagnosis of OSA. It has also been shown to be able to discriminate among the different degrees of severity of OSA. Additional large studies aiming to validate this questionnaire as a screening or diagnostic test are needed.
authors.affiliation: Maxillo Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
authors.forename: Giulio
authors.initials: G
authors.lastname: Gasparini
authors.affiliation: Special Surgery Department, Ear-Nose-Throat Unit, Morgagni-Pierantoni Hospital, Forlì, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Vicini
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Hospital Fazzi, Lecce, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: De Benedetto
authors.affiliation: Department of Otolaryngology, S. Pio X Hospital, Milan, Italy.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Salamanca
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, S. Orsola-Malpighi University Hospital, Bologna, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Sorrenti
authors.affiliation: Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy ; Department of Periodontology, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Romandini
authors.affiliation: Special Surgery Department, Ear-Nose-Throat Unit, Morgagni-Pierantoni Hospital, Forlì, Italy.
authors.forename: Marcello
authors.initials: M
authors.lastname: Bosi
authors.affiliation: Maxillo Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
authors.forename: Gianmarco
authors.initials: G
authors.lastname: Saponaro
authors.affiliation: Maxillo Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Foresta
authors.affiliation: Maxillo Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
authors.forename: Andreina
authors.initials: A
authors.lastname: Laforì
authors.affiliation: Special Surgery Department, Ear-Nose-Throat Unit, Morgagni-Pierantoni Hospital, Forlì, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Meccariello
authors.affiliation: Department of Otolaryngology, S. Pio X Hospital, Milan, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Bianchi
authors.affiliation: "A. Galateo" Respiratory Rehabilitation Unit, San Cesario di Lecce, Italy.
authors.forename: Domenico Maurizio
authors.initials: DM
authors.lastname: Toraldo
authors.affiliation: Special Surgery Department, Ear-Nose-Throat Unit, Morgagni-Pierantoni Hospital, Forlì, Italy.
authors.forename: Aldo
authors.initials: A
authors.lastname: Campanini
authors.affiliation: Special Surgery Department, Ear-Nose-Throat Unit, Morgagni-Pierantoni Hospital, Forlì, Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Montevecchi
authors.affiliation: Department of Neurology, Complesso Integrato Columbus, Rome, Italy.
authors.forename: Grazia
authors.initials: G
authors.lastname: Rizzotto
authors.affiliation: Maxillo Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Cervelli
authors.affiliation: Maxillo Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Moro
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Hospital Fazzi, Lecce, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Arigliani
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, S. Orsola-Malpighi University Hospital, Bologna, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Gobbi
authors.affiliation: Maxillo Facial Surgery, Complesso Integrato Columbus, Catholic University Medical School, Rome, Italy.
authors.forename: Sandro
authors.initials: S
authors.lastname: Pelo
mesh_terms: D000328:Adult; D000368:Aged; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D059026:Diagnostic Self Evaluation; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D017286:Polysomnography / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis*; D011795:Surveys and Questionnaires