title: A New Golden Age of Natural Products Drug Discovery.
abstract: The 2015 Nobel Prize in Physiology or Medicine has been awarded to William C. Campbell, Satoshi Omura, and Youyou Tu for the discovery of avermectins and artemisinin, respectively, therapies that revolutionized the treatment of devastating parasite diseases. With the recent technological advances, a New Golden Age of natural products drug discovery is dawning.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458, USA; Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458, USA; Natural Products Library Initiative at The Scripps Research Institute, The Scripps Research Institute, Jupiter, FL 33458, USA; Xiangya International Academy of Translational Medicine, Central South University, Changsha, Hunan 410013, China. Electronic address: shenb@scripps.edu.
authors.forename: Ben
authors.initials: B
authors.lastname: Shen
mesh_terms: D037621:Artemisinins / Q000737:chemistry / Q000627:therapeutic use; D055808:Drug Discovery; D006666:History of Medicine; D049674:History, 21st Century; D007559:Ivermectin / Q000031:analogs & derivatives / Q000737:chemistry / Q000627:therapeutic use; D009613:Nobel Prize; D010272:Parasitic Diseases / Q000188:drug therapy*; D010827:Physiology / Q000266:history
chemical_list: D037621:Artemisinins; D007559:Ivermectin; C019264:avermectin; C031327:artemisinin