title: Idiopathic central diabetes insipidus presenting in a very low birth weight infant successfully managed with lyophilized sublingual desmopressin.
abstract: Neonatal central diabetes insipidus (DI) is an extremely rare disorder that can cause severe morbidity and mortality. We have reported a very low birth weight infant with idiopathic central DI presenting in the first month of life who was successfully treated with sublingual desmopressin therapy. In this report, we emphasize that central DI should be kept in mind in an infant with unexplained hypernatremia and polyuria. Timely diagnosis and treatment with lyophilized desmopressin may prevent severe morbidity and mortality.
authors.affiliation: Department of Neonatology, Adana Gynecology and Obstetric and Children's Hospital, Adana, Turkey. dhanta@gmail.com.
authors.forename: Deniz
authors.initials: D
authors.lastname: Hanta
authors.forename: Birgin
authors.initials: B
authors.lastname: Törer
authors.forename: Fatih
authors.initials: F
authors.lastname: Temiz
authors.forename: Hasan
authors.initials: H
authors.lastname: Kılıçdağ
authors.forename: Mahmut
authors.initials: M
authors.lastname: Gökçe
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Erdoğan
mesh_terms: D000286:Administration, Sublingual; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage* / Q000627:therapeutic use; D020790:Diabetes Insipidus, Neurogenic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D008279:Magnetic Resonance Imaging; D035583:Rare Diseases
chemical_list: D003894:Deamino Arginine Vasopressin