title: Age-Related Sleep Changes and its Implication in Neurodegenerative Diseases.
abstract: In the article authors discuss the current data on sleep changes with aging focusing on the influence of age-related degenerative changes in orexin-containing and pacemaker brain areas. Pathophysiological mechanisms of sleep disturbances in Parkinson's and Alzheimer's diseases have much in common with normal age neurophysiological changes. Maintenance of the sleep-promoting systems function could positively modify the course of these diseases.
authors.forename: Elena A
authors.initials: EA
authors.lastname: Lyashenko
authors.affiliation: Department of Nervous Diseases, Institute of Professional Education, I.M. Sechenov 1-st MSMU, 11/1 Rossolimo str. Moscow 119435, Russia. polouekt@mail.ru.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Poluektov
authors.forename: Oleg S
authors.initials: OS
authors.lastname: Levin
authors.forename: Polina V
authors.initials: PV
authors.lastname: Pchelina
mesh_terms: D000375:Aging; D000544:Alzheimer Disease; D000818:Animals; D002940:Circadian Rhythm; D006801:Humans; D019636:Neurodegenerative Diseases; D012890:Sleep; D012893:Sleep Wake Disorders