title: Development and Validation of an Inexpensive, Simple, and Rapid Technique for Measuring the Accuracy of Extemporaneously Compounded Pharmaceuticals.
abstract: Use of ultraviolet detection to quantitate analytes is a basic concept of analytical chemistry. The basis of this application is well defined by Beer-Lambert's law. To this end, the authors applied Beer-Lambert's law as a simple and rapid tool to measure the accuracy of extemporaneously compounded pharmaceuticals. Using two commonly extemporaneously compounded formulations, the authors demonstrated the application of this tool. Advantages and limitations of the ultraviolet-visible technique are discussed. The authors speculate that more advanced spectral techniques for quality control will be adopted in the future. These techniques will be more accurate and will be associated with fewer limitations. However, costs associated with use will be greater.
authors.forename: Claudia
authors.initials: C
authors.lastname: Meek
authors.forename: Andrew
authors.initials: A
authors.lastname: Rothardt
authors.forename: Jason
authors.initials: J
authors.lastname: Evans
authors.forename: Rosanne
authors.initials: R
authors.lastname: Thurman
authors.forename: Lisa
authors.initials: L
authors.lastname: Ashworth
authors.forename: Richard
authors.initials: R
authors.lastname: Leff
mesh_terms: D004339:Drug Compounding / Q000379:methods* / Q000592:standards; D011786:Quality Control; D013056:Spectrophotometry, Ultraviolet