title: Diagnostic accuracy of body mass index to identify obesity in older adults: NHANES 1999-2004.
abstract: Body composition changes with aging lead to increased adiposity and decreased muscle mass, making the diagnosis of obesity challenging. Conventional anthropometry, including body mass index (BMI), while easy to use clinically may misrepresent adiposity. We determined the diagnostic accuracy of BMI using dual-energy X-ray absorptiometry (DEXA) in assessing the degree of obesity in older adults.
  
  
  
  The National Health and Nutrition Examination Surveys 1999-2004 were used to identify adults aged ⩾60 years with DEXA measures. They were categorized (yes/no) as having elevated body fat by gender (men: ⩾25%; women ⩾35%) and by BMI ⩾25 and ⩾30 kg m(-)(2). The diagnostic performance of BMI was assessed. Metabolic characteristics were compared in discordant cases of BMI/body fat. Weighting and analyses were performed per NHANES (National Health and Nutrition Examination Survey) guidelines.
  
  
  
  We identified 4984 subjects (men: 2453; women: 2531). Mean BMI and % body fat was 28.0 kg m(-2) and 30.8% in men, and 28.5 kg m(-)(2) and 42.1% in women. A BMI ⩾30 kg m(-)(2) had a low sensitivity and moderately high specificity (men: 32.9 and 80.8%, concordance index 0.66; women: 38.5 and 78.5%, concordance 0.69) correctly classifying 41.0 and 45.1% of obese subjects. A BMI ⩾25 kg m(-2) had a moderately high sensitivity and specificity (men: 80.7 and 99.6%, concordance 0.81; women: 76.9 and 98.8%, concordance 0.84) correctly classifying 80.8 and 78.5% of obese subjects. In subjects with BMI <30 kg m(-)(2), body fat was considered elevated in 67.1% and 61.5% of men and women, respectively. For a BMI ⩾30 kg m(-)(2), sensitivity drops from 40.3% to 14.5% and 44.5% to 23.4%, whereas specificity remains elevated (>98%), in men and women, respectively, in those 60-69.9 years to subjects aged ⩾80 years. Correct classification of obesity using a cutoff of 30 kg m(-)(2) drops from 48.1 to 23.9% and 49.0 to 19.6%, in men and women in these two age groups.
  
  
  
  Traditional measures poorly identify obesity in the elderly. In older adults, BMI may be a suboptimal marker for adiposity.
authors.affiliation: Section of General Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.|Geisel School of Medicine at Dartmouth and The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH, USA.|Dartmouth Centers for Health and Aging, Dartmouth College, Hanover, NH, USA.|Health Promotion Research Center at Dartmouth, Lebanon, NH, USA.|Dartmouth Weight and Wellness Center, Lebanon, NH, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Batsis
authors.affiliation: Geisel School of Medicine at Dartmouth and The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH, USA.
authors.forename: T A
authors.initials: TA
authors.lastname: Mackenzie
authors.affiliation: Geisel School of Medicine at Dartmouth and The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH, USA.|Dartmouth Centers for Health and Aging, Dartmouth College, Hanover, NH, USA.|Health Promotion Research Center at Dartmouth, Lebanon, NH, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Bartels
authors.affiliation: Division of Cardiovascular Disease, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: K R
authors.initials: KR
authors.lastname: Sahakyan
authors.affiliation: Division of Cardiovascular Disease, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: V K
authors.initials: VK
authors.lastname: Somers
authors.affiliation: Division of Cardiovascular Disease, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: F
authors.initials: F
authors.lastname: Lopez-Jimenez
mesh_terms: D015502:Absorptiometry, Photon / Q000592:standards*; D050154:Adiposity / Q000502:physiology*; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology / Q000517:prevention & control; D008875:Middle Aged; D009749:Nutrition Surveys; D009765:Obesity / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D015203:Reproducibility of Results; D014481:United States / Q000453:epidemiology