title: Reactivation of coccidioidomycosis: a prosthetic joint infection in Spain.
abstract: A resident of Spain was found to have a prosthetic knee infection due to coccidioidomycosis. He had a history of having pneumonia which resolved while living in an area of California endemic for Coccidioides in 1957-1961. The patient left California in 1961 returned to Spain and never left Spain thereafter. In 2006, a total knee replacement was done. In 2013, a prosthetic knee infection was documented due to coccidioidomycosis. By molecular DNA analysis, Coccidioides immitis was identified from the knee tissue, a species most commonly found in California. This represents reactivation of a Coccidioides infection 56 years after leaving the endemic area.
authors.affiliation: Orthopedics and Traumatology, Complejo Hospitalario de Navarra, C/Irunlarrea n3, 31008, Pamplona, Spain.|Secretaria de Traumatologia y Cirugia Ortopédica, Clinica Ubarmin, Carretera Aoiz s/n., Elacno/Egües,, 31486, Navarra, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Arbeloa-Gutierrez
authors.affiliation: Department of Internal Medicine, Infectious Diseases, Maricopa Medical Center, 77 East Missouri Avenue, Unit 73, Phoenix, AZ, 85012, USA. tjkubs@aol.com.
authors.forename: T
authors.initials: T
authors.lastname: Kuberski
authors.affiliation: Department of Medical Microbiology and Immunology, School of Medicine, University of California Davis, Davis, CA, 95616, USA.
authors.forename: S M
authors.initials: SM
authors.lastname: Johnson
authors.affiliation: Orthopedics and Traumatology, Complejo Hospitalario de Navarra, C/Irunlarrea n3, 31008, Pamplona, Spain.|Secretaria de Traumatologia y Cirugia Ortopédica, Clinica Ubarmin, Carretera Aoiz s/n., Elacno/Egües,, 31486, Navarra, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Sagastibelza
authors.affiliation: Department of Medicine de Clinica Ubarmin, Complejo Hospitalario de Navarra, C/Irunlarrea n3, 31008, Pamplona, Spain.
authors.forename: J I
authors.initials: JI
authors.lastname: Alaez
authors.affiliation: Department of Medical Microbiology and Immunology, School of Medicine, University of California Davis, Davis, CA, 95616, USA.
authors.forename: D
authors.initials: D
authors.lastname: Pappagianis
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D003045:Coccidioides / Q000235:genetics / Q000302:isolation & purification*; D003047:Coccidioidomycosis / Q000473:pathology*; D006801:Humans; D007720:Knee Prosthesis / Q000382:microbiology*; D008297:Male; D011014:Pneumonia / Q000382:microbiology*; D012008:Recurrence; D013030:Spain