title: Epidemiological Analysis of Mycobacterium tuberculosis Strains Isolated from Patients of Small Communities Living in the South-East of Poland.
abstract: The diversity of Mycobacterium tuberculosis clinical isolates, collected from a single hospital, was analyzed by ligation-mediated PCR techniques: FLiP and FLAP, and hybridization technique, IS6110-RFLP. The isolated strains were divided in terms of location (3 towns of Podkarpackie voivodeship differing in population size) and relationship (8 members of 4 families, each represented by 2 patients). Within each family identical DNA profiles, as well as drug resistance patterns were identified indicating a great chance of transmission of strains within the same family. Identical, or very similar patterns were also shared by strains isolated from unrelated patients living in a very small town (1 200 inhabitants) or hospitalized in the same place and time.
authors.forename: Anna
authors.initials: A
authors.lastname: Zaczek
authors.forename: Iwona
authors.initials: I
authors.lastname: Szwaja
authors.forename: Monika
authors.initials: M
authors.lastname: Skiba
authors.forename: Anna
authors.initials: A
authors.lastname: Brzostek
authors.forename: Czesław
authors.initials: C
authors.lastname: Puchalski
authors.forename: Karolina
authors.initials: K
authors.lastname: Lewandowska
authors.forename: Jarosław
authors.initials: J
authors.lastname: Dziadek
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D011044:Poland / Q000453:epidemiology; D012150:Polymorphism, Restriction Fragment Length; D012111:Residence Characteristics; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000382:microbiology*; D055815:Young Adult