title: Advanced interatrial block predicts clinical recurrence of atrial fibrillation after catheter ablation.
abstract: It has been demonstrated that advanced interatrial block (IAB) is associated with an increased risk of atrial fibrillation (AF); however, the impact of advanced IAB on recurrence of paroxysmal AF after catheter ablation is not clear.
  
  
  
  204 consecutive patients with paroxysmal AF who underwent index circumferential pulmonary vein (PV) isolation were prospectively enrolled. In all patients, a resting electrocardiogram in sinus rhythm was evaluated for the presence of advanced IAB, defined as a P-wave duration >120ms and biphasic (±) morphology in the inferior leads. Advanced IAB was detected in 20.1% of patients. AF recurrence was defined as the occurrence of confirmed atrial tachyarrhythmia lasting more than 30s beyond 3 months after the catheter ablation in the absence of any antiarrhythmic treatment.
  
  
  
  During the mean follow-up period of 13.9±6.2 months (range, 3-27 months), 62 patients (30.4%) developed recurrence of AF. The recurrence rate was higher in patients with advanced IAB than those without advanced IAB (46.3% vs. 26.4%, p=0.006). Cox regression analysis with adjustment for age, P-wave duration, CHADS2 score, and PV isolation identified advanced IAB (hazard ratio, 2.111; 95% confidence interval, 1.034-4.308; p=0.040) and left atrial diameter (hazard ratio, 1.051; 95% confidence interval, 1.004-1.100; p=0.034) as two independent predictors of recurrence of AF.
  
  
  
  Patients with advanced IAB were at an increased risk of AF recurrence after catheter ablation.
authors.affiliation: Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China.
authors.forename: Jin-Tao
authors.initials: JT
authors.lastname: Wu
authors.affiliation: Department of Cardiology, Center for Atrial Fibrillation, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
authors.forename: De-Yong
authors.initials: DY
authors.lastname: Long
authors.affiliation: Department of Cardiology, Center for Atrial Fibrillation, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
authors.forename: Jian-Zeng
authors.initials: JZ
authors.lastname: Dong
authors.affiliation: Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China.
authors.forename: Shan-Ling
authors.initials: SL
authors.lastname: Wang
authors.affiliation: Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China.
authors.forename: Xian-Wei
authors.initials: XW
authors.lastname: Fan
authors.affiliation: Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China.
authors.forename: Hai-Tao
authors.initials: HT
authors.lastname: Yang
authors.affiliation: Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China.
authors.forename: Hong-Yan
authors.initials: HY
authors.lastname: Duan
authors.affiliation: Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China.
authors.forename: Li-Jie
authors.initials: LJ
authors.lastname: Yan
authors.affiliation: Department of Cardiology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Qian
authors.affiliation: Department of Cardiology, Henan Medical College, Zhengzhou, China. Electronic address: ycksyy@126.com.
authors.forename: Chao-Kuan
authors.initials: CK
authors.lastname: Yang
mesh_terms: D001281:Atrial Fibrillation / Q000601:surgery*; D017115:Catheter Ablation; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006325:Heart Atria; D006327:Heart Block / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011667:Pulmonary Veins / Q000601:surgery; D012008:Recurrence
keywords: Advanced interatrial block; Atrial fibrillation; Catheter ablation; Recurrence