title: [The effectiveness of RF ablation of ventricular ectopic beats made using selected mapping techniques].
abstract: Only several world-leading centers have summarized outcomes of invasive therapy of ventricular arrhythmia.
  
  
  OBJECTIVE
  The aim of the work is to compare the effectiveness of RF ablation of ventricular arrhythmia.
  
  
  METHODS
  183 patients (111 males, mean age 50 ± 17) underwent RF ablation of ventricular ecopic beats (VEB). Retrospective analysis of procedural protocols, in- and outpatient medical records was performed. RF ablation was done using electroanatomical CARTO system, Pacemapping or both methods (CARTO + Pacemapping).
  
  
  RESULTS
  Long-term ablation effectiveness was as follows: CARTO - success rate assessed during the ablation procedure was 84,4%; during post operation period follow-up 70,3%, and in long term followup 71,1%; Pacemaping-success rate assessed during the ablation procedure was 91,7%; during post operation period follow-up 83,3%, and in long term follow-up 75,0%; CARTO + Pacemaping - success rate assessed during the ablation procedure was 85,4%; during post operation period follow-up 70,8%, and in long term follow-up 77,1%. Mean amount of VEBs per day before ablation was 18750 ± 12560 (2435 to 50000) and after ablation 575 ± 428 (0 to 1550), p<0.001. Best results were achieved in cases where both mapping techniques were used in combination. Among clinical parameters affecting long-term ablation effectiveness, only hypertension was found to significantly decrease long-term effectiveness of VEB ablation. Only ablation temperature and energy affected long-term therapy effect significantly (p<0,0014; HR=0,84). After the ablation, there was improvement of the left-ventricular end-diastolic diameter and ejection fraction.
  
  
  CONCLUSIONS
  Long-term success of ventricular extrasystoly ablation in combined method (CARTO+Pacemapping) was slightly higher compared in CARTO technique and in Pacemapping technique. Classic RF ablation is effective and safe, therefore it can be considered as first-line therapy. In ablation, precise localization of arrhythmic focus is the most important factor. Ablation temperature and energy were significantly correlated to long-term ablation effectiveness. After ventricular extrasystoly ablation, left ventricle ejection fraction increased and left ventricle end-diastolic diameter decreased. Hypertension significantly decreased long-term effectiveness of ventricular extrasystoly ablation.
authors.affiliation: The John Paul II Hospital in Kraków, Department of Electrocardiology.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Senderek
authors.affiliation: The John Paul II Hospital in Kraków, Department of Electrocardiology.
authors.forename: Jacek
authors.initials: J
authors.lastname: Bednarek
authors.affiliation: Student Scientific Society of Biomedical Engineering - InBio Division of Biomedical Computer Science Department of Computer Science and Materials Science University of Silesia.
authors.forename: Jacek
authors.initials: J
authors.lastname: Lelakowski
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018780:Body Surface Potential Mapping; D017115:Catheter Ablation; D015897:Comorbidity; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018879:Ventricular Premature Complexes / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery*; D055815:Young Adult
keywords: CARTO; Pacemapping system; RF ablation; ventricular ectopic beats