title: GnRH agonist trigger does not always cause luteolysis: a case report.
abstract: This study reports an IVF patient with excessive ovarian response, who received gonadotrophin-releasing hormone agonist (GnRHa) triggering. Fourteen oocytes were retrieved, and one embryo transferred 2 days later. Although no further luteal support was given, close follow-up showed consistently high oestradiol and progesterone concentrations, so no exogenous luteal support was given. A clinical pregnancy was achieved without signs or symptoms of ovarian hyperstimulation syndrome. This case report highlights the importance of individual follow-up post agonist trigger.
authors.affiliation: Department of Obstetrics and Gynecology, IVF Unit, Rambam Health Care Campus, Haifa, Israel. Electronic address: skol@rambam.health.gov.il.
authors.forename: Shahar
authors.initials: S
authors.lastname: Kol
authors.affiliation: Department of Obstetrics and Gynecology, IVF Unit, Rambam Health Care Campus, Haifa, Israel.
authors.forename: Tatiana
authors.initials: T
authors.lastname: Breyzman
mesh_terms: D005260:Female; D005300:Fertility Agents, Female / Q000494:pharmacology* / Q000627:therapeutic use; D005307:Fertilization in Vitro; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006801:Humans; D008183:Luteal Phase / Q000187:drug effects; D003341:Luteolysis / Q000187:drug effects*; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D005300:Fertility Agents, Female; D007987:Gonadotropin-Releasing Hormone
keywords: GnRHa trigger; luteal coasting; luteal support; luteolysis; ovarian hyperstimulation syndrome