title: Treatment of Latent Tuberculosis Infection in Children.
abstract: Treatment of latent tuberculosis infection (LTBI) is an effective way of preventing future cases of tuberculosis disease. We review pediatric and adult studies of LTBI treatment (isoniazid and rifampin monotherapy, isoniazid plus rifampin, isoniazid plus rifapentine, and rifampin plus pyrazinamide). Based upon this review and our pediatric experience, we can offer recommendations for routine (isoniazid) and alternative courses of therapy.
authors.affiliation: The Tuberculosis Initiative of Texas Children's Hospital, and Sections of Infectious Diseases Emergency Medicine acruz@bcm.edu.
authors.forename: Andrea T
authors.initials: AT
authors.lastname: Cruz
authors.affiliation: Division of Infectious Diseases, Department of Pediatrics, Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: Amina
authors.initials: A
authors.lastname: Ahmed
authors.affiliation: The Tuberculosis Initiative of Texas Children's Hospital, and Sections of The Tuberculosis Initiative of Texas Children's Hospital, and Sections of.
authors.forename: Anna M
authors.initials: AM
authors.lastname: Mandalakas
authors.affiliation: The Tuberculosis Initiative of Texas Children's Hospital, and Sections of Infectious Diseases.
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Starke
keywords: Adherence; Directly Observed Preventive Therapy; Latent Tuberculosis Infection