title: Glucagonoma syndrome: A case report.
abstract: Necrolytic migratory erythema (NME), diabetes mellitus and glucagon-secreting tumors form the hallmarks of glucagonoma syndrome, and represent the major clinical manifestations of glucagonoma. NME is usually presented as the initial complaint of patients. Due to the rare incidence of glucagonoma, its diagnosis is often delayed, which leads to its progression. Here, we report a case of NME with a typical skin rash, which was misdiagnosed and treated with corticosteroids for two years. Removal of the tumor in the pancreatic body led to the rapid relief of the symptoms. The aim of the present study is to demonstrate the typical characteristics of glucagonoma syndrome to clinicians in order to improve its diagnosis and treatment.
authors.affiliation: The Pancreas Center of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
authors.forename: Jishu
authors.initials: J
authors.lastname: Wei
authors.affiliation: The Pancreas Center of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
authors.forename: Shibo
authors.initials: S
authors.lastname: Lin
authors.affiliation: Department of Pathology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
authors.forename: Cong
authors.initials: C
authors.lastname: Wang
authors.affiliation: The Pancreas Center of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
authors.forename: Junli
authors.initials: J
authors.lastname: Wu
authors.affiliation: The Pancreas Center of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
authors.forename: Zhuyin
authors.initials: Z
authors.lastname: Qian
authors.affiliation: The Pancreas Center of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
authors.forename: Cuncai
authors.initials: C
authors.lastname: Dai
authors.affiliation: The Pancreas Center of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
authors.forename: Kuirong
authors.initials: K
authors.lastname: Jiang
authors.affiliation: The Pancreas Center of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
authors.forename: Y I
authors.initials: YI
authors.lastname: Miao
keywords: diabetes mellitus; glucagonoma; necrolytic migratory erythema