title: Sedative load, carious teeth and infection in the periodontium among community-dwelling older people.
abstract: OBJECTIVE
  To study the relation of sedative load to carious teeth and periodontal pocketing - indication of infectious periodontal disease - among older people.
  
  
  METHODS
  This cross-sectional study was based on a subpopulation of 158 community-dwelling, dentate, non-smoking, 75-year-old or older people from the Oral Health Geriatric Multidisciplinary Strategy study. The data were collected by interviews and clinical oral examinations during 2004-2005. Sedative load was measured by means of the sedative load model, and Poisson multivariate regression models were used to estimate relative risk (RR) with 95% confidence intervals (CI).
  
  
  RESULTS
  Participants with a sedative load of either 1-2 (n = 31) or ≥3 (n = 12) had an increased likelihood of having carious teeth (RR: 1.8, CI: 1.2-2.6 and RR: 2.4, CI: 1.4-4.1, respectively) compared to participants without a sedative load. There was an inverse association between sedative load and the number of teeth with periodontal pockets.
  
  
  CONCLUSIONS
  Presence of dental caries was associated with the use of drugs with sedative properties. The use of drugs with sedative properties was not associated with the presence of periodontal pockets.
authors.affiliation: Periodontology and Geriatric Dentistry, Center of Oral Health Sciences Research, University of Oulu, Oulu, Finland.
authors.forename: Antti
authors.initials: A
authors.lastname: Tiisanoja
authors.affiliation: Periodontology and Geriatric Dentistry, Center of Oral Health Sciences Research, University of Oulu, Oulu, Finland.|Dental Training Clinic, Social and Health services, Oulu, Finland.|Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
authors.forename: Anna-Maija
authors.initials: AM
authors.lastname: Syrjälä
authors.affiliation: School of Pharmacy, University of Eastern Finland, Kuopio, Finland.|Social and Health Centre of Kuopio, Kuopio, Finland.
authors.forename: Kaija
authors.initials: K
authors.lastname: Komulainen
authors.affiliation: Department of Social Pharmacy, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.|Unit of Clinical Pharmacology and Geriatric Pharmacotherapy, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
authors.forename: Sirpa
authors.initials: S
authors.lastname: Hartikainen
authors.affiliation: Department of Social Pharmacy, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.|Unit of Clinical Pharmacology and Geriatric Pharmacotherapy, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
authors.forename: Heidi
authors.initials: H
authors.lastname: Taipale
authors.affiliation: Periodontology and Geriatric Dentistry, Center of Oral Health Sciences Research, University of Oulu, Oulu, Finland.
authors.forename: Matti
authors.initials: M
authors.lastname: Knuuttila
authors.affiliation: Periodontology and Geriatric Dentistry, Center of Oral Health Sciences Research, University of Oulu, Oulu, Finland.|Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.|Institute of Dentistry, University of Eastern Finland, Kuopio, Finland.|Department of Oral and Maxillofacial Diseases, Kuopio University Hospital, Kuopio, Finland.
authors.forename: Pekka
authors.initials: P
authors.lastname: Ylöstalo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003731:Dental Caries / Q000453:epidemiology*; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D057187:Independent Living / Q000706:statistics & numerical data; D008297:Male; D010514:Periodontal Pocket / Q000453:epidemiology*; D016012:Poisson Distribution; D012306:Risk
chemical_list: D006993:Hypnotics and Sedatives
keywords: aged; dental caries; independent living; periodontitis; sedative load