title: Radiological and clinical results following high-dose intensity-modulated radiotherapy in recurrent craniopharyngioma: A case report.
abstract: Craniopharyngiomas (CPs) are rare benign suprasellar tumors. The standard treatment for CP is complete surgical resection or partial resection followed by adjuvant radiotherapy (RT). Adjuvant RT is typically administered at a total dose of 54 Gy with 1.8 Gy/fraction. The current study reported the case of a young patient affected by recurrent craniopharyngioma, who was treated with irradiation subsequent to several surgical resections. Image fusion and intensity-modulated radiation therapy techniques were employed to deliver a high total dose (63 Gy with 2.1 Gy/fraction) with no severe acute toxicities recorded. At the 6-year follow-up, no radiological or clinical signs of disease progression or late sequelae were observed.
authors.affiliation: Radiology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Pierro
authors.affiliation: Medical Physics Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy.
authors.forename: Savino
authors.initials: S
authors.lastname: Cilla
authors.affiliation: Radiation Oncology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Picardi
authors.affiliation: Radiation Oncology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy.
authors.forename: Marica
authors.initials: M
authors.lastname: Ferro
authors.affiliation: Radiation Oncology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Macchia
authors.affiliation: Radiation Oncology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Deodato
authors.affiliation: Radiation Oncology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy.
authors.forename: Milly
authors.initials: M
authors.lastname: Buwenge
authors.affiliation: Radiology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy.
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Sallustio
authors.affiliation: Radiation Oncology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy ; General Oncology Unit, Fondazione di Ricerca e Cura 'Giovanni Paolo II', Università Cattolica del Sacro Cuore, Campobasso 86100, Italy ; Radiation Oncology Unit, Department of Experimental, Diagnostic and Specialty Medicine, DIMES University of Bologna, S. Orsola-Malpighi Hospital, Bologna 40138, Italy.
authors.forename: Alessio G
authors.initials: AG
authors.lastname: Morganti
keywords: case report; craniopharyngioma; intensity-modulated radiation therapy; pediatric