title: Synchronous primary breast cancer and hepatocellular carcinoma in a male patient: a case report.
abstract: Male breast cancer is a rare malignant disease characterized by hormonal imbalance. Hepatocellular carcinoma (HCC) is the most common neoplasm of the liver, and is generally correlated with hepatitis B or C virus-related cirrhosis. While to our knowledge a case with these two malignant diseases in a same male patient in the concomitant period is an exceptional event, rarely reported in literature. In this report, we present a case in which a Chinese patient with hepatitis B developed a tumor mass that originated from segment V of the liver and presented with right breast nodules at the same time. Synchronous mastectomy and hepatectomy were performed, and standard endocrine therapy and chemotherapy as adjuvant treatment were therefore followed. The diverse histogenesis of the two kinds of cancers highlights the need for us to investigate any common physiopathogenetic elements.
authors.affiliation: Cancer Institute and Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing 100021, People's Republic of China.
authors.forename: Fei
authors.initials: F
authors.lastname: Tian
authors.affiliation: Cancer Institute and Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing 100021, People's Republic of China.
authors.forename: Xiuzheng
authors.initials: X
authors.lastname: Cui
authors.affiliation: Cancer Institute and Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing 100021, People's Republic of China.
authors.forename: Lin
authors.initials: L
authors.lastname: Li
authors.affiliation: Cancer Institute and Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing 100021, People's Republic of China.
authors.forename: Haizhen
authors.initials: H
authors.lastname: Lu
authors.affiliation: Cancer Institute and Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing 100021, People's Republic of China.
authors.forename: Weiqi
authors.initials: W
authors.lastname: Rong
authors.affiliation: Cancer Institute and Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing 100021, People's Republic of China.
authors.forename: Chao
authors.initials: C
authors.lastname: Bi
authors.affiliation: Cancer Institute and Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences Beijing 100021, People's Republic of China.
authors.forename: Jianxiong
authors.initials: J
authors.lastname: Wu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D018567:Breast Neoplasms, Male / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D006509:Hepatitis B / Q000150:complications; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor
keywords: Male breast cancer; hepatocellular carcinoma; synchronous resection