title: Nanoparticle Probes for Structural and Functional Photoacoustic Molecular Tomography.
abstract: Nowadays, nanoparticle probes have received extensive attention largely due to its potential biomedical applications in structural, functional, and molecular imaging. In addition, photoacoustic tomography (PAT), a method based on the photoacoustic effect, is widely recognized as a robust modality to evaluate the structure and function of biological tissues with high optical contrast and high acoustic resolution. The combination of PAT with nanoparticle probes holds promises for detecting and imaging diseased tissues or monitoring their treatments with high sensitivity. This review will introduce the recent advances in the emerging field of nanoparticle probes and their preclinical applications in PAT, as well as relevant perspectives on future development.
authors.affiliation: State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, Jilin 130012, China ; Bioimaging Core, Faculty of Health Sciences, University of Macau, Taipa, Macau.
authors.forename: Haobin
authors.initials: H
authors.lastname: Chen
authors.affiliation: Bioimaging Core, Faculty of Health Sciences, University of Macau, Taipa, Macau.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Yuan
authors.affiliation: State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun, Jilin 130012, China.
authors.forename: Changfeng
authors.initials: C
authors.lastname: Wu
mesh_terms: D000818:Animals; D006801:Humans; D057054:Molecular Imaging / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods; D014054:Tomography / Q000379:methods