title: Effects of the organophosphorus pesticide Folisuper 600 (methyl parathion) on the heart function of bullfrog tadpoles, Lithobates catesbeianus (Shaw, 1802).
abstract: The aim of this work was to evaluate whether the heart function of bullfrog tadpoles (25 Gosner stage) is affected by their acute exposure (48 h) to a sub-lethal concentration (10 µg.L-1) of the active principle of the organophosphorus pesticide Folisuper 600R (methyl parathion - MP). Our results demonstrated that MP causes not only a reduction in tadpoles' cardiac ventricular mass, resulting in a marked reduction in their cardiac twitch force, but also impairs their swimming performance, irrespective of increasing their heart rate. Together, these findings indicate that low and realistic concentration of MP have a negative impact on tadpoles' performance, jeopardizing their survival.
authors.affiliation: Departamento de Biologia, Universidade Federal de São Carlos, Sorocaba, SP, Brazil.
authors.forename: M J
authors.initials: MJ
authors.lastname: Costa
authors.affiliation: Departamento de Biologia, Universidade Federal de São Carlos, Sorocaba, SP, Brazil.
authors.forename: L R
authors.initials: LR
authors.lastname: Ribeiro
authors.affiliation: Departamento de Biologia, Universidade Federal de São Carlos, Sorocaba, SP, Brazil.
authors.forename: R F
authors.initials: RF
authors.lastname: Salla
authors.affiliation: Departamento de Biologia, Universidade Federal de São Carlos, Sorocaba, SP, Brazil.
authors.forename: F U
authors.initials: FU
authors.lastname: Gamero
authors.affiliation: Departamento de Biologia, Universidade Federal de São Carlos, Sorocaba, SP, Brazil.
authors.forename: L M L M
authors.initials: LM
authors.lastname: Alves
authors.affiliation: Departamento de Biologia, Universidade Federal de São Carlos, Sorocaba, SP, Brazil.
authors.forename: E C M
authors.initials: EC
authors.lastname: Silva-Zacarin
mesh_terms: D000818:Animals; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D007306:Insecticides / Q000633:toxicity*; D007814:Larva / Q000187:drug effects / Q000254:growth & development / Q000502:physiology; D008743:Methyl Parathion / Q000633:toxicity*; D011892:Rana catesbeiana / Q000254:growth & development / Q000502:physiology*; D013550:Swimming
chemical_list: D007306:Insecticides; D008743:Methyl Parathion