title: Electrophilic Cyanate As a Recognition Motif for Reactive Sulfur Species: Selective Fluorescence Detection of H2S.
abstract: An ESIPT-based fluorescent dye, 3-hydroxyflavone, is chemically masked with an electrophilic cyanate motif in order to construct a fluorescent probe for cellular sulfur species. This novel probe structure, displays an extremely fast, highly sensitive and selective "turn-on" type fluorescent response toward H2S. We have also documented its utility for imaging of H2S in the living cells.
authors.affiliation: Department of Chemistry, Faculty of Science, İzmir Institute of Technology, Urla , 35430, İzmir, Turkey.
authors.forename: Erman
authors.initials: E
authors.lastname: Karakuş
authors.affiliation: Department of Chemistry, Faculty of Science, İzmir Institute of Technology, Urla , 35430, İzmir, Turkey.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Üçüncü
authors.affiliation: Department of Chemistry, Faculty of Science, İzmir Institute of Technology, Urla , 35430, İzmir, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Emrullahoğlu
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival; D003485:Cyanates / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D006862:Hydrogen Sulfide / Q000032:analysis* / Q000737:chemistry*; D015394:Molecular Structure; D013050:Spectrometry, Fluorescence
chemical_list: D003485:Cyanates; D005419:Flavonoids; D005456:Fluorescent Dyes; D006862:Hydrogen Sulfide; C041477:3-hydroxyflavone