title: The role of preoperative breast magnetic resonance (MR) imaging for surgical decision in patients with triple-negative breast cancer.
abstract: BACKGROUND
  Several reliable randomized studies do not recommend routine preoperative breast MR imaging for patients with breast cancer. However, because the principle of MR imaging is based on the dynamics of contrast enhancement, a specific biologic subgroup of tumors should sensitively respond to the imaging process.
  
  
  METHODS
  From 2008 to 2013, 918 eligible patients with breast cancer underwent breast surgery and were divided into two groups based on preoperative breast MR findings: patients in whom the surgical plan was changed and those in whom the surgical plan remained unchanged. We investigated the changing patterns of breast surgery based on routine mammography, ultrasound, and preoperative breast magnetic resonance (MR) findings and analyzed the association between additional suspicious lesions on breast MR imaging and clinicopathologic factors.
  
  
  RESULTS
  Additional suspicious breast lesions were detected on preoperative MR imaging in 104 cases (11.3%), and the surgical strategy was changed as the final decision in 97 cases (10.6%). There was no difference between oncologic results between two groups. However, the triple-negative breast cancer (TNBC) was significantly associated with changing of the surgical strategy based on breast MR findings (P = 0.048).
  
  
  CONCLUSIONS
  Additional preoperative breast MR imaging may be helpful in surgical decision for patients with TNBC.
authors.affiliation: Department of Surgery, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Jeeyeon
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Surgery, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Jin Hyang
authors.initials: JH
authors.lastname: Jung
authors.affiliation: Department of Surgery, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Wan Wook
authors.initials: WW
authors.lastname: Kim
authors.affiliation: Department of Surgery, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Seung Ook
authors.initials: SO
authors.lastname: Hwang
authors.affiliation: Department of Radiology, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Hye Jung
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Pathology, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Park
authors.affiliation: Department of Hemato-Oncology, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Yee Soo
authors.initials: YS
authors.lastname: Chae
authors.affiliation: Department of Plastic and Reconstructive Surgery, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Jung Dug
authors.initials: JD
authors.lastname: Yang
authors.affiliation: Department of Surgery, Kyungpook National University, School of Medicine, Daegu, Republic of Korea.
authors.forename: Ho Yong
authors.initials: HY
authors.lastname: Park
mesh_terms: D000328:Adult; D000066491:Clinical Decision-Making; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008408:Mastectomy / Q000379:methods*; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D057234:Preoperative Period; D064726:Triple Negative Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D016217:Ultrasonography, Mammary
keywords: MR; breast; carcinoma; surgery