title: NetMatchStar: an enhanced Cytoscape network querying app.
abstract: We present NetMatchStar, a Cytoscape app to find all the occurrences of a query graph in a network and check for its significance as a motif with respect to seven different random models. The query can be uploaded or built from scratch using Cytoscape facilities. The app significantly enhances the previous NetMatch in style, performance and functionality. Notably NetMatchStar allows queries with wildcards.
authors.affiliation: Department of Math and Computer Science, University of Catania, Catania, 95125, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Rinnone
authors.affiliation: Department of Math and Computer Science, University of Catania, Catania, 95125, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Micale
authors.affiliation: Department of Computer Science, University of Verona, Verona, 37134, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Bonnici
authors.affiliation: The Donnelly Centre, University of Toronto, Toronto, ON, M5S 3E1, Canada.
authors.forename: Gary D
authors.initials: GD
authors.lastname: Bader
authors.affiliation: Department of Computer Science, Courant Institute of Mathematical Sciences, New York University, New York, NY, 10012, USA.
authors.forename: Dennis
authors.initials: D
authors.lastname: Shasha
authors.affiliation: Department of Clinical and Experimental Medicine, University of Catania, Catania, 95125, Italy.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Ferro
authors.affiliation: Department of Clinical and Experimental Medicine, University of Catania, Catania, 95125, Italy.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Pulvirenti
authors.affiliation: Department of Clinical and Experimental Medicine, University of Catania, Catania, 95125, Italy.
authors.forename: Rosalba
authors.initials: R
authors.lastname: Giugno
keywords: approximate graph matching; background network models; biological network motifs; cytoscape app; exact graph matching; network querying; randomization; statistical significance