title: Flexor Tendon Repair: Healing, Biomechanics, and Suture Configurations.
abstract: Successful outcome after flexor tendon repair requires a delicate balance between tendon healing and limiting scar tissue formation. Recent studies have highlighted the importance of the number of core sutures crossing the repair and the benefits of specific suture configurations in determining the strength of tendon repair. Researchers have attempted to augment the biological environment to improve the speed and strength of tendon repair.
authors.affiliation: Department of Orthopaedics, University of Pittsburgh, Suite 1010, Kaufmann Building, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Myer
authors.affiliation: Department of Orthopaedics, University of Pittsburgh, Suite 1010, Kaufmann Building, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA. Electronic address: johnfowler10@gmail.com.
authors.forename: John R
authors.initials: JR
authors.lastname: Fowler
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001696:Biomechanical Phenomena; D005355:Fibrosis; D005385:Fingers / Q000502:physiology*; D006801:Humans; D016328:NF-kappa B / Q000502:physiology; D016059:Range of Motion, Articular; D013537:Sutures; D013708:Tendon Injuries / Q000503:physiopathology* / Q000601:surgery*; D013710:Tendons / Q000033:anatomy & histology / Q000473:pathology; D000267:Tissue Adhesions / Q000517:prevention & control; D016212:Transforming Growth Factor beta / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D016328:NF-kappa B; D016212:Transforming Growth Factor beta
keywords: Biological augmentation; Biomechanics; Flexor tendon; Growth factors; Suture configuration