title: [Is morphine indicated in patients with cardiac asthma? Indications for negative effects from the use of morphine].
abstract: According to current Dutch and European guidelines, morphine has a place in the treatment of patients with cardiac asthma. There are no studies showing an improvement in objective parameters with the use of morphine in patients with cardiac asthma. Recent large retrospective cohort studies indicate an increased mortality risk among patients given morphine in the treatment of cardiac asthma, even after correction for confounders. In addition, morphine may be linked to an increased risk of intensive care unit admission. Morphine should be used with caution in patients with cardiac asthma.
authors.affiliation: Ziekenhuis Gelderse Vallei, Ede.
authors.forename: Thijs W H
authors.initials: TW
authors.lastname: Flinsenberg
authors.forename: Joep
authors.initials: J
authors.lastname: van der Leeuw
authors.forename: Asaf
authors.initials: A
authors.lastname: Gafni
authors.forename: Antonie J H H M
authors.initials: AJ
authors.lastname: van Oostrom
authors.forename: Jeroen P H
authors.initials: JP
authors.lastname: van Wijk
mesh_terms: D001249:Asthma / Q000401:mortality / Q000628:therapy*; D004417:Dyspnea / Q000503:physiopathology / Q000628:therapy; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006760:Hospitalization; D006801:Humans; D007362:Intensive Care Units; D009020:Morphine / Q000009:adverse effects* / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies
chemical_list: D009020:Morphine