title: Comparison of Vitamin D levels in cases with preeclampsia, eclampsia and healthy pregnant women.
abstract: The aim of this study is to assess vitamin D levels in eclampsia, preeclampsia and healthy pregnant women and the role of vitamin D deficiency in the etiology of preeclampsia (PE). Forty healthy pregnant women, 83 preeclamptic and 32 eclamptic pregnant women were included. Maternal and infant medical records were reviewed. Blood samples were obtained from all groups. Demographics and serum vitamin D levels were compared between the groups. No statistical differences were observed in age, gravidity, parity, weight, height and BMI between the three groups. Week of pregnancy and weight at birth in eclamptic and preeclamptic patients were lower compared to the healthy patients (P<0.001 and P<0.001, respectively). Systolic and diastolic blood pressures were higher in eclamptic (P<0.001) and preeclamptic patients (P<0.001) compared to the healthy pregnant group. The rate of cesarean section was found to be higher in preeclamptic and eclamptic patients (P<0.001). Vitamin D levels were lower in both preeclamptic and eclamptic patients compared to healthy normotensive pregnant women (P<0.001). Preeclamptic and eclamptic women were similar in terms of the data compared. Vitamin D supplementation is considered to decrease the risk of both preeclampsia and eclampsia in the patient population at risk for vitamin D deficiency.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaraş, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Bakacak
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaraş, Turkey.
authors.forename: Salih
authors.initials: S
authors.lastname: Serin
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaraş, Turkey.
authors.forename: Onder
authors.initials: O
authors.lastname: Ercan
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaraş, Turkey.
authors.forename: Bülent
authors.initials: B
authors.lastname: Köstü
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaraş, Turkey.
authors.forename: Fazıl
authors.initials: F
authors.lastname: Avci
authors.affiliation: Department of Biochemistry, School of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaraş, Turkey.
authors.forename: Metin
authors.initials: M
authors.lastname: Kılınç
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaraş, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Kıran
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Kahramanmaras Sutcu Imam University Kahramanmaraş, Turkey.
authors.forename: Gürkan
authors.initials: G
authors.lastname: Kiran
keywords: 25-hydroxy vitamin D; Vitamin D; eclampsia; hypertension; preeclampsia