title: Sexually transmitted infections and viral hepatitides in patients presenting for non-occupational HIV post-exposure prophylaxis: results of a prospective cohort study.
abstract: Data evaluating the screening practices for viral hepatitides and sexually transmitted infections (STIs) in patients presenting for non-occupational HIV post-exposure prophylaxis (nPEP) care are limited. Screening practices and prevalences of viral hepatitides and STIs were evaluated in 126 patients presenting to a dedicated HIV prevention clinic for HIV nPEP. Three patients (2.4%) were diagnosed with chronic hepatitis C infection, 28 (22.2%) did not have surface antibodies in sufficient quantity to confer immunity to hepatitis B, and six (4.8%) were diagnosed with an STI. A multivariate regression model did not predict any demographic or clinical features predictive of HBV non-immunity. Beyond screening for HIV infection, evaluation for viral hepatitides and STIs is an important feature in the care of patients presenting for HIV nPEP.
authors.affiliation: Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Nirojini
authors.initials: N
authors.lastname: Sivachandran
authors.affiliation: Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Reed A C
authors.initials: RA
authors.lastname: Siemieniuk
authors.affiliation: Immunodeficiency Clinic, Toronto General Hospital, Toronto, Ontario, Canada.
authors.forename: Pauline
authors.initials: P
authors.lastname: Murphy
authors.affiliation: Immunodeficiency Clinic, Toronto General Hospital, Toronto, Ontario, Canada.
authors.forename: Andrea
authors.initials: A
authors.lastname: Sharp
authors.affiliation: Immunodeficiency Clinic, Toronto General Hospital, Toronto, Ontario, Canada.
authors.forename: Christine
authors.initials: C
authors.lastname: Walach
authors.affiliation: Immunodeficiency Clinic, Toronto General Hospital, Toronto, Ontario, Canada.
authors.forename: Tania
authors.initials: T
authors.lastname: Placido
authors.affiliation: Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Immunodeficiency Clinic, Toronto General Hospital, Toronto, Ontario, Canada; Divisions of Internal Medicine and Infectious Diseases, University Health Network, Toronto General Hospital, 14EN-209, 200 Elizabeth Street, Toronto, ON, Canada M5G 2C4. Electronic address: isaac.bogoch@uhn.ca.
authors.forename: Isaac I
authors.initials: II
authors.lastname: Bogoch
mesh_terms: D000328:Adult; D000554:Ambulatory Care Facilities; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002690:Chlamydia Infections / Q000150:complications / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D006509:Hepatitis B / Q000150:complications / Q000453:epidemiology; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D056990:Post-Exposure Prophylaxis; D011446:Prospective Studies; D012307:Risk Factors; D012749:Sexually Transmitted Diseases / Q000150:complications / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents
keywords: HIV; Hepatitis B; Hepatitis C; PEP; Post-exposure prophylaxis; Sexually transmitted infections