title: Influence of social factors on patient-reported late symptoms: Report from a controlled trial among long-term head and neck cancer survivors in Denmark.
abstract: The incidence of head and neck cancer and morbidity and mortality after treatment are associated with social factors. Whether social factors also play a role in the prevalence of late-onset symptoms after treatment for head and neck cancer is not clear.
  
  
  
  Three hundred sixty-nine survivors completed questionnaires on late symptoms and functioning.
  
  
  
  Survivors with short education were more likely to report severe problems than those with medium or long education. In the fully adjusted model, the risk for problems with opening the mouth remained significantly increased (odds ratio [OR] = 3.20; 95% confidence interval [CI] = 1.18-8.63). For survivors who lived alone, the adjusted ORs were significantly increased for physical functioning (2.17; 95% CI = 1.01-4.68) and trouble with social eating (OR = 2.26; 95% CI = 1.14-4.47).
  
  
  
  Self-reported severe late symptoms were more prevalent in survivors with short education and in those living alone, suggesting differences in perception of late symptoms between social groups. © 2015 Wiley Periodicals, Inc. Head Neck 38: E1713-E1721, 2016.
authors.affiliation: Department of Survivorship, Danish Cancer Society Research Center, Copenhagen, Denmark.
authors.forename: Trille Kristina
authors.initials: TK
authors.lastname: Kjaer
authors.affiliation: Department of Survivorship, Danish Cancer Society Research Center, Copenhagen, Denmark.|Department of Oncology, Rigshospitalet, Copenhagen, Denmark.
authors.forename: Christoffer
authors.initials: C
authors.lastname: Johansen
authors.affiliation: Department of Oncology, Herlev Hospital, Herlev Ringvej, Denmark.
authors.forename: Elo
authors.initials: E
authors.lastname: Andersen
authors.affiliation: Department of Survivorship, Danish Cancer Society Research Center, Copenhagen, Denmark.
authors.forename: Randi
authors.initials: R
authors.lastname: Karlsen
authors.affiliation: Department of Oncology, Herlev Hospital, Herlev Ringvej, Denmark.
authors.forename: Anni Linnet
authors.initials: AL
authors.lastname: Nielsen
authors.affiliation: Department of Statistics, Bioinformatics and Registry, Danish Cancer Society Research Center, Copenhagen, Denmark.
authors.forename: Kirsten
authors.initials: K
authors.lastname: Frederiksen
authors.affiliation: Department of Clinical Medicine, Rigshospitalet, Copenhagen, Denmark.
authors.forename: Mikael
authors.initials: M
authors.lastname: Rørth
authors.affiliation: Research Center for Prevention and Health, Glostrup Hospital, Glostrup, Denmark.
authors.forename: Else
authors.initials: E
authors.lastname: Ibfelt
authors.affiliation: Department of Survivorship, Danish Cancer Society Research Center, Copenhagen, Denmark.
authors.forename: Susanne Oksbjerg
authors.initials: SO
authors.lastname: Dalton
mesh_terms: D000368:Aged; D000073116:Cancer Survivors; D003718:Denmark; D004522:Educational Status; D005191:Family Characteristics; D005260:Female; D006258:Head and Neck Neoplasms / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D058992:Social Participation; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
keywords: cancer treatment; head and neck cancer; late symptoms; social factors; survivor