title: Exertional Leg Pain.
abstract: Exertional leg pain is a common condition seen in runners and the general population. Given the broad differential diagnosis of this complaint, this article focuses on the incidence, anatomy, pathophysiology, clinical presentation, diagnostic evaluation, and management of common causes that include medial tibial stress syndrome, tibial bone stress injury, chronic exertional compartment syndrome, arterial endofibrosis, popliteal artery entrapment syndrome, and entrapment of the common peroneal, superficial peroneal, and saphenous nerves. Successful diagnosis of these conditions hinges on performing a thorough history and physical examination followed by proper diagnostic testing and appropriate management.
authors.affiliation: Department of Orthopaedics and Rehabilitation, University of Iowa Sports Medicine, 2701 Prairie Meadow Drive, Iowa City, IA 52242, USA; Division of Physical Medicine and Rehabilitation, University of Alberta, 10230 111 Avenue Northwest, Edmonton, AB T5G 0B7, Canada. Electronic address: sathish.k.rajasekaran@gmail.com.
authors.forename: Sathish
authors.initials: S
authors.lastname: Rajasekaran
authors.affiliation: Department of Physical Medicine and Rehabilitation, Mayo Clinic School of Medicine, 200 1st St SW, Rochester, MN 55905, USA; Department of Physical Medicine and Rehabilitation, University of California Davis School of Medicine, 4860 Y Street, Sacramento, CA 95817, USA; Mayo Clinic Sports Medicine Center, Mayo Clinic Square, 600 Hennepin Avenue, Suite 310, Minneapolis, MN 55403, USA.
authors.forename: Jonathan T
authors.initials: JT
authors.lastname: Finnoff
mesh_terms: D001265:Athletic Injuries / Q000175:diagnosis* / Q000628:therapy*; D003937:Diagnosis, Differential; D006801:Humans; D007866:Leg; D008487:Medical History Taking; D010146:Pain / Q000175:diagnosis* / Q000209:etiology*; D059408:Pain Management / Q000379:methods*; D010147:Pain Measurement; D010808:Physical Examination; D005082:Physical Exertion; D012307:Risk Factors; D012420:Running / Q000293:injuries*
keywords: Athletic injuries; Compartment syndromes; Iliac artery; Leg injuries; Medial tibial stress syndrome; Nerve compression syndromes; Popliteal artery; Stress fractures