title: Diagnosis and Management of Periprosthetic Elbow Infection.
abstract: ➤ Periprosthetic elbow infections rarely involve systemic symptoms such as fever or malaise.➤ Unlike tests for periprosthetic hip and knee infections, the diagnostic utility of blood testing and joint aspiration for periprosthetic elbow infection has not been demonstrated to date.➤ Intraoperative histological analysis has good specificity (93.1%) but very low sensitivity (51.3%) for periprosthetic elbow infection.➤ Emerging diagnostic options such as implant sonication, molecular analysis, and advanced synovial fluid cytokine and protein analysis may reduce diagnostic uncertainty in the future.➤ Recommended surgical treatment options for an infection at the site of an elbow arthroplasty include implant retention and debridement, two-stage revision with or without techniques for restoration of bone stock and triceps continuity, and resection arthroplasty.
authors.affiliation: Department of Orthopaedics, University of Texas Health Science Center at San Antonio, 7730 Floyd Curl Drive, San Antonio, TX 78229. E-mail address: jeremysomerson@gmail.com.
authors.forename: Jeremy S
authors.initials: JS
authors.lastname: Somerson
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, 200 First Street S.W., Rochester, MN 55905.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Morrey
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, 200 First Street S.W., Rochester, MN 55905.
authors.forename: Joaquin
authors.initials: J
authors.lastname: Sanchez-Sotelo
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, 200 First Street S.W., Rochester, MN 55905.
authors.forename: Bernard F
authors.initials: BF
authors.lastname: Morrey
mesh_terms: D000465:Algorithms; D000900:Anti-Bacterial Agents; D001174:Arthrodesis; D057929:Arthroplasty, Replacement, Elbow / Q000295:instrumentation*; D003131:Combined Modality Therapy; D003646:Debridement; D003661:Decision Support Techniques; D058569:Elbow Prosthesis / Q000009:adverse effects*; D006801:Humans; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000628:therapy; D012086:Reoperation
chemical_list: D000900:Anti-Bacterial Agents