title: Glucocorticoid-induced Osteoporosis.
abstract: Glucocorticoid-induced osteoporosis (GIOP) is one of the most common and serious adverse effects associated with glucocorticoid use. This article highlights GIOP pathophysiology, epidemiologic associations, effective treatment, and lifestyle modifications that can reduce fracture risk for long-term glucocorticoid users and additionally emphasizes the importance of early intervention.
authors.affiliation: Division of Clinical Immunology and Rheumatology, 851 Faculty Office Tower, 510 20th Street South, Birmingham, AL 35294, USA.
authors.forename: Xena
authors.initials: X
authors.lastname: Whittier
authors.affiliation: Division of Clinical Immunology and Rheumatology, Department of Medicine, Center for Education and Research on Therapeutics (CERTs), Center for Outcomes, Effectiveness Research and Education (COERE), Center of Research Translation (CORT) in Gout and Hyperuricemia, University of Alabama at Birmingham, 820 Faculty Office Tower, 510 20th Street South, Birmingham, AL 35294, USA. Electronic address: ksaag@uab.edu.
authors.forename: Kenneth G
authors.initials: KG
authors.lastname: Saag
mesh_terms: D015519:Bone Density; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D010024:Osteoporosis / Q000139:chemically induced* / Q000188:drug therapy / Q000517:prevention & control; D058866:Osteoporotic Fractures / Q000139:chemically induced* / Q000517:prevention & control; D018570:Risk Assessment
chemical_list: D050071:Bone Density Conservation Agents; D005938:Glucocorticoids
keywords: Fracture risk; Glucocorticoids; Osteoporosis; Prevention