title: Admix'em: a flexible framework for forward-time simulations of hybrid populations with selection and mate choice.
abstract: We introduce a new forward-time simulator, Admix'em, that allows for rapid and realistic simulations of admixed populations with selection. Complex selection can be achieved through user-defined fitness and mating-preference probability functions. Users can specify realistic genomic landscapes and model neutral SNPs in addition to sites under selection. Admix'em is designed to simulate selection in admixed populations but can also be used as a general population simulator. Usage and examples are in the supplement.
  
  
  
  C ++ and OpenMP, supports 64-bit Linux/Unix-like platforms. https://github.com/melop/admixem
  
  
  
  rcui@age.mpg.de
  
  
  
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Department of Biology, Texas A&M University, College Station, TX 77843, USA, Centro De Investigaciones Científicas De Las Huastecas "Aguazarca", Calnali, Mexico and Max Planck Institute for the Biology of Aging, Cologne, Germany.
authors.forename: Rongfeng
authors.initials: R
authors.lastname: Cui
authors.affiliation: Centro De Investigaciones Científicas De Las Huastecas "Aguazarca", Calnali, Mexico and.
authors.forename: Molly
authors.initials: M
authors.lastname: Schumer
authors.affiliation: Department of Biology, Texas A&M University, College Station, TX 77843, USA, Centro De Investigaciones Científicas De Las Huastecas "Aguazarca", Calnali, Mexico and.
authors.forename: Gil G
authors.initials: GG
authors.lastname: Rosenthal
mesh_terms: D004843:Epistasis, Genetic; D005828:Genetics, Population; D016678:Genome; D023281:Genomics / Q000379:methods*; D020641:Polymorphism, Single Nucleotide; D012641:Selection, Genetic; D012984:Software