title: Saggy skin as a presenting sign of angioimmunoblastic T-cell lymphoma.
abstract: Angioimmunoblastic T-cell lymphoma (AITL) is a rare, aggressive form of peripheral T-cell lymphoma that has a variety of cutaneous manifestations. To our knowledge, saggy skin has not been documented as one of these manifestations. We report a case of a patient with angioimmunoblastic T-cell lymphoma presenting initially with pruritus and saggy skin, which later progressed into erythroderma despite chemotherapy; the disease eventually resolved with autologous stem cell transplant. Appreciating the cutaneous manifestations of AITL may allow for earlier diagnosis and treatment.
authors.affiliation: Department of Dermatology, St George Hospital, Kogarah, Sydney, NSW, Australia.|Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors.forename: N G
authors.initials: NG
authors.lastname: Maher
authors.affiliation: Department of Dermatology, St George Hospital, Kogarah, Sydney, NSW, Australia.
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Chiang
authors.affiliation: Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.|Department of Haematology, St George Hospital, Kogarah, Sydney, NSW, Australia.
authors.forename: X
authors.initials: X
authors.lastname: Badoux
authors.affiliation: Department of Anatomical Pathology, South Eastern Area Laboratory Services (SEALS), NSW Health Pathology, St George Hospital, Kogarah, Sydney, NSW, Australia.
authors.forename: L W
authors.initials: LW
authors.lastname: Vonthethoff
authors.affiliation: Department of Dermatology, St George Hospital, Kogarah, Sydney, NSW, Australia.|Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors.forename: D F
authors.initials: DF
authors.lastname: Murrell
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D004890:Erythema / Q000473:pathology; D005528:Foot / Q000473:pathology; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000473:pathology*; D016411:Lymphoma, T-Cell, Peripheral / Q000473:pathology*; D008297:Male; D011537:Pruritus; D012867:Skin / Q000473:pathology*; D013601:T-Lymphocytes / Q000502:physiology
chemical_list: D000970:Antineoplastic Agents