title: FDG PET/CT Imaging of Carotid Atherosclerosis.
abstract: Atherosclerosis is a complex inflammatory process and an integral component of myocardial infarction and stroke. Atherosclerotic plaques can be detected using ultrasonography, myocardial perfusion imaging, coronary angiography, multidetector computed tomography (CT), and MR imaging. These modalities assess the luminal encroachment of the plaques or the structural features. Imaging plaque biology in concert with plaque structure may provide important insights. PET scanning using (18)F fluorodeoxyglucose. ((18)F FDG-PET) is commonly combined with CT scanning to characterize oncological processes. This review examines the role of (18)F FDG-PET/CT imaging in the characterization of atherosclerotic plaque biology.
authors.affiliation: Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
authors.forename: Abdelrahman
authors.initials: A
authors.lastname: Ali
authors.affiliation: Cardiac MR PET CT Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: atawakol@partners.org.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Tawakol
mesh_terms: D000465:Algorithms; D000818:Animals; D016893:Carotid Stenosis / Q000175:diagnosis*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Arterial inflammation; Atherosclerosis; CVD; FDG-PET; Stroke