title: Multicomponent Cascade Synthesis of Trifluoroethyl Isoquinolines from Alkynes and Vinyl Azides.
abstract: A multicomponent cascade reaction is described that provides concise access to the trifluoroethyl isoquinolines using a Rh(III)-Cu(II) bimetallic system and readily available Togni's reagent. The system tolerates various vinyl azides and internal alkynes. Experimental results suggest that Togni's reagent might act as a CF3 radical supplier.
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai, 200237, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Liu
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai, 200237, China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Chen
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai, 200237, China.
authors.forename: Xing Guang
authors.initials: XG
authors.lastname: Li
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai, 200237, China.
authors.forename: Pei Nian
authors.initials: PN
authors.lastname: Liu