title: Intravenous immunoglobulin in acute Sydenham's chorea: A systematic review.
abstract: Sydenham's chorea (SC) is a major manifestation seen in 25% of patients with acute rheumatic fever. SC is the prototypic autoimmune neurological disorder, which has a less appreciated associated risk of psychiatric morbidity. We undertook a systematic review to examine whether the use of intravenous immunoglobulin affects clinical recovery and morbidity.
authors.affiliation: Neuroimmunology Group, Institute for Neuroscience and Muscle Research, The Kids Research Institute at the Children's Hospital at Westmead, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Shekeeb S
authors.initials: SS
authors.lastname: Mohammad
authors.affiliation: Neuroimmunology Group, Institute for Neuroscience and Muscle Research, The Kids Research Institute at the Children's Hospital at Westmead, University of Sydney, Sydney, New South Wales, Australia.|Paediatric Neurology Unit, Department of Paediatrics, University of Padua, Italy.
authors.forename: Margherita
authors.initials: M
authors.lastname: Nosadini
authors.affiliation: TY Nelson Department of Neurology and Neurosurgery, The Children's Hospital at Westmead, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Padraic
authors.initials: P
authors.lastname: Grattan-Smith
authors.affiliation: Neuroimmunology Group, Institute for Neuroscience and Muscle Research, The Kids Research Institute at the Children's Hospital at Westmead, University of Sydney, Sydney, New South Wales, Australia.|TY Nelson Department of Neurology and Neurosurgery, The Children's Hospital at Westmead, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Russell C
authors.initials: RC
authors.lastname: Dale
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D002819:Chorea / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D012213:Rheumatic Fever / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous
keywords: behavioural; developmental; general paediatrics; immunology; neurology