title: Hippocampal Transections for Epilepsy.
abstract: Multiple hippocampal transection (MHT) is a novel surgical procedure that serves to disrupt seizure propagation fibers within the hippocampus without impairing verbal memory or the loss of stem cells. Given the paucity of literature regarding the utility and long-term outcome of MHT, a review is presented of the current literature to support the utility of this procedure in the treatment of intractable temporal lobe epilepsy. Long-term outcome analysis of this technique has been reported by 2 independent groups. Both groups used intraoperative electrocorticography. All patients underwent multiple subpial transection on the neocortex and MHT on the hippocampus.
authors.affiliation: Creighton University Medical Center, Division of Neurosurgery, 601 North 30th Street, Omaha, NE 68131, USA. Electronic address: arun.patil@alegent.org.
authors.forename: Arun Angelo
authors.initials: AA
authors.lastname: Patil
authors.affiliation: Creighton University Medical Center, Division of Neurosurgery, 601 North 30th Street, Omaha, NE 68131, USA.
authors.forename: Andrea Jennifer
authors.initials: AJ
authors.lastname: Chamczuk
authors.affiliation: 11930 Arbor Street, Omaha, NE 68144, USA.
authors.forename: Richard V
authors.initials: RV
authors.lastname: Andrews
mesh_terms: D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D006624:Hippocampus / Q000601:surgery*; D006801:Humans
keywords: Long-term outcome; Multiple hippocampal transection; Temporal lobe epilepsy; Verbal memory