title: Effect of Contrast on Visual Spatial Summation in Different Cell Categories in Cat Primary Visual Cortex.
abstract: Multiple cell classes have been found in the primary visual cortex, but the relationship between cell types and spatial summation has seldom been studied. Parvalbumin-expressing inhibitory interneurons can be distinguished from pyramidal neurons based on their briefer action potential durations. In this study, we classified V1 cells into fast-spiking units (FSUs) and regular-spiking units (RSUs) and then examined spatial summation at high and low contrast. Our results revealed that the excitatory classical receptive field and the suppressive non-classical receptive field expanded at low contrast for both FSUs and RSUs, but the expansion was more marked for the RSUs than for the FSUs. For most V1 neurons, surround suppression varied as the contrast changed from high to low. However, FSUs exhibited no significant difference in the strength of suppression between high and low contrast, although the overall suppression decreased significantly at low contrast for the RSUs. Our results suggest that the modulation of spatial summation by stimulus contrast differs across populations of neurons in the cat primary visual cortex.
authors.affiliation: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Chen
authors.affiliation: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.
authors.forename: Ai-Min
authors.initials: AM
authors.lastname: Ding
authors.affiliation: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.
authors.forename: Xiao-Hua
authors.initials: XH
authors.lastname: Liang
authors.affiliation: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.
authors.forename: Li-Peng
authors.initials: LP
authors.lastname: Zhang
authors.affiliation: Key Laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.affiliation: Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Song
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002415:Cats; D010320:Parvalbumins / Q000096:biosynthesis; D017966:Pyramidal Cells / Q000166:cytology / Q000502:physiology; D014793:Visual Cortex / Q000166:cytology / Q000502:physiology
chemical_list: D010320:Parvalbumins