title: Frontotemporal Dementia.
abstract: Frontotemporal dementia (FTD) is a not-uncommon explanation for progressive cognitive deficit in patients who often have a genetic susceptibility for such a neurodegenerative process. However, FTD does not seem to identify one particular pathogenetic mechanism but rather a spectrum of pathologies with particular predilection for the frontal and temporal lobes of the brain. There have been various subcategorizations of this form of dementia that have a tendency to be of earlier onset than typical Alzheimer disease and heralded by behavioral or communication manifestations. There is a behavioral variant and a language variant, referred to as primary progressive aphasia.
authors.affiliation: Department of Neurology, Tulane University School of Medicine, 1430 Tulane Avenue, 8065, New Orleans, LA 70112, USA. Electronic address: rkelley2@tulane.edu.
authors.forename: Roger E
authors.initials: RE
authors.lastname: Kelley
authors.affiliation: Department of Neurology, Tulane University School of Medicine, 1430 Tulane Avenue, 8065, New Orleans, LA 70112, USA.
authors.forename: Ramy
authors.initials: R
authors.lastname: El-Khoury
mesh_terms: D018888:Aphasia, Primary Progressive / Q000175:diagnosis* / Q000473:pathology; D001921:Brain / Q000473:pathology*; D057180:Frontotemporal Dementia / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D009483:Neuropsychological Tests
keywords: Abulia; Aphasia neurodegenerative disorder; Behavioral disturbance; Dementia; Disinhibition; Impulsivity; Inattention