title: Bronchoconstriction following instillation of phenylephrine eye drops in premature infants with bronchopulmonary dysplasia: two cases report.
abstract: Premature infants requiring an ophthalmic examination or even surgery for retinopathy of prematurity (ROP) have a high prevalence of co-existing bronchopulmonary dysplasia (BPD). Reactive airway is one of the clinical presentations of BPD. We report two cases of bronchoconstriction following instillation of mydriatic eye drops. One occurred during induction of anesthesia for laser photocoagulation and the other before screening of ROP. The most likely cause in each case was phenylephrine eye drops. We recommend that the minimal dosage of phenylephrine needed to attain proper mydriasis should be instilled to infant patients, and the possibility of bronchoconstriction occurrence kept in mind, especially for infants with low body weight with BPD.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Keimyung University School of Medicine, Daegu, Korea.
authors.forename: Hyun Jee
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Anesthesiology and Pain Medicine, Keimyung University School of Medicine, Daegu, Korea.
authors.forename: Jin Guk
authors.initials: JG
authors.lastname: Choi
authors.affiliation: Department of Anesthesiology and Pain Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Kyung-Hwa
authors.initials: KH
authors.lastname: Kwak
keywords: Bronchoconstriction; Bronchopulmonary dysplasia; Phenylephrine; Retinopathy of prematurity