title: Successful Use of Temocillin as Salvage Therapy for Cervical Osteomyelitis Secondary to Multidrug-Resistant Burkholderia cepacia.
abstract: Infection with multidrug resistant Burkholderia cepacia presents a therapeutic challenge in patients with cystic fibrosis. In this study, we present a case of progressive cervical osteomyelitis secondary to B cepacia that failed surgical drainage and extended therapy with meropenem, piperacillin-tazobactam, doxycycline, and aminoglycosides. Temocillin (Negaban) was successfully used to clear the infection.
authors.affiliation: Department of Pediatrics, Southern Illinois University School of Medicine, Springfield; and Departments of mrodriguez@siumed.edu.
authors.forename: Marcela
authors.initials: M
authors.lastname: Rodriguez
authors.affiliation: Pediatrics.
authors.forename: Miranda
authors.initials: M
authors.lastname: Nelson
authors.affiliation: Radiology, Washington University School of Medicine, St Louis, Missouri.
authors.forename: James E
authors.initials: JE
authors.lastname: Kelly
authors.affiliation: Pediatrics.
authors.forename: Alexis
authors.initials: A
authors.lastname: Elward
authors.affiliation: Pediatrics.
authors.forename: Sharon Celeste
authors.initials: SC
authors.lastname: Morley
keywords: Burkholderia cepacia; cystic fibrosis; multidrug-resistant; vertebral osteomyelitis