title: [Pulmonary embolism].
abstract: Pulmonary embolism is a potentially fatal disorder and frequently seen in critical care and emergency medicine. Due to a high mortality rate within the first few hours, the accurate initiation of rational diagnostic pathways in patients with suspected pulmonary embolism and timely consecutive treatment is essential. In this review, the current European guidelines on the diagnosis and therapy of acute pulmonary embolism are presented. Special focus is put on a structured patient management based on the individual risk of early mortality. In particular risk assessment and new risk-adjusted treatment recommendations are presented and discussed in this article.
authors.affiliation: Medizinische Klinik II, Universitätsklinikum Gießen und Marburg, Standort Gießen, Klinikstraße 33, 35392, Gießen, Deutschland. matthias.hecker@innere.med.uni-giessen.de.
authors.forename: M
authors.initials: M
authors.lastname: Hecker
authors.affiliation: Medizinische Klinik II, Universitätsklinikum Gießen und Marburg, Standort Gießen, Klinikstraße 33, 35392, Gießen, Deutschland.
authors.forename: N
authors.initials: N
authors.lastname: Sommer
authors.affiliation: Klinik für Allgemein-, Viszeral-, Thorax-, Transplantations- und Kinderchirurgie, Universitätsklinikum Gießen und Marburg, Standort Gießen, Gießen, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Hecker
authors.affiliation: Abteilung für Anästhesie und Intensivmedizin, Kerckhoff-Klinik Bad Nauheim, Bad Nauheim, Deutschland.
authors.forename: D
authors.initials: D
authors.lastname: Bandorski
authors.affiliation: Klinik für Anästhesiologie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
authors.forename: M A
authors.initials: MA
authors.lastname: Weigand
authors.affiliation: Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Gießen, Justus-Liebig-Universität Gießen, Gießen, Deutschland.
authors.forename: G A
authors.initials: GA
authors.lastname: Krombach
authors.affiliation: Klinik für Thoraxchirurgie, Kerckhoff-Klinik Bad Nauheim, Bad Nauheim, Deutschland.
authors.forename: E
authors.initials: E
authors.lastname: Mayer
authors.affiliation: Medizinische Klinik II, Universitätsklinikum Gießen und Marburg, Standort Gießen, Klinikstraße 33, 35392, Gießen, Deutschland.
authors.forename: D
authors.initials: D
authors.lastname: Walmrath
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D002423:Cause of Death; D000072226:Computed Tomography Angiography; D003422:Critical Care; D061345:Early Medical Intervention; D004636:Emergency Service, Hospital; D019983:Guideline Adherence; D006801:Humans; D061330:Multidetector Computed Tomography; D011379:Prognosis; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000188:drug therapy* / Q000401:mortality; D018570:Risk Assessment; D015912:Thrombolytic Therapy / Q000379:methods*
chemical_list: D000925:Anticoagulants
keywords: D-dimer; Lung diseases; Probability; Risk factors; Therapeutic thrombolysis