title: Descemet's Stripping Automated Endothelial Keratoplasty versus Descemet's Membrane Endothelial Keratoplasty in the Fellow Eye for Fuchs Endothelial Dystrophy: A Retrospective Study.
abstract: OBJECTIVE
  To evaluate visual outcome and endothelial cell density (ECD) after Descemet's Membrane Endothelial Keratoplasty (DMEK) in comparison with Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) in the fellow eye for Fuchs endothelial dystrophy (FED).
  
  
  METHODS
  Single-centre, retrospective case series.
  
  
  METHODS
  30 eyes of 30 patients undergoing DMEK, who completed a 1-year follow-up, were compared with 30 fellow eyes which underwent DSAEK for bilateral FED. Main outcome measures studied included Best Corrected Visual Acuity (BCVA) and ECD during a 1-year follow-up period.
  
  
  RESULTS
  BCVA improved from 0.78 ± 0.35 logMAR, and 0.73 ± 0.31 logMAR before surgery to 0.22 ± 0.1 logMAR and 0.35 ± 0.12 logMAR 6 months after DMEK and DSEK, respectively (P < 0.001). At one year after surgery, the BCVA was maintained at 0.21 ± 0.12 logMAR and 0.34 ± 0.1 logMAR, respectively, after DMEK and DSAEK. A statistically better visual outcome was observed after DMEK compared to DSAEK (P < 0.05) in fellow eyes.
  
  
  CONCLUSIONS
  DMEK provided better visual rehabilitation when compared to DSAEK. Nevertheless, there were no significant differences with regard to the ECD within a 1-year follow-up.
authors.affiliation: Sankara Eye Centre, Coimbatore 641035, India.
authors.forename: Vipul
authors.initials: V
authors.lastname: Bhandari
authors.affiliation: Sankara Eye Centre, Coimbatore 641035, India.
authors.forename: Jagdeesh K
authors.initials: JK
authors.lastname: Reddy
authors.affiliation: Sankara Eye Centre, Coimbatore 641035, India.
authors.forename: Kirti
authors.initials: K
authors.lastname: Relekar
authors.affiliation: Sankara Eye Centre, Coimbatore 641035, India.
authors.forename: Vijayalakshmi
authors.initials: V
authors.lastname: Prabhu
mesh_terms: D000328:Adult; D000368:Aged; D057111:Descemet Stripping Endothelial Keratoplasty / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005642:Fuchs' Endothelial Dystrophy / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014786:Vision Disorders / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery*; D014792:Visual Acuity