title: Hierarchical Plasmonic Nanorods and Upconversion Core-Satellite Nanoassemblies for Multimodal Imaging-Guided Combination Phototherapy.
abstract: DNA-driven hierarchical core-satellite nanostructures with plasmonic gold nanorod dimers and upconversion nanoparticles are fabricated. Once the core-satellite structure is activated, combined photothermal therapy and photodynamic therapy are carried out under the guidance of upconversion luminesce, T1 -weighted magnetic resonance, photoacoustics, and computed tomography imaging of tumors in vivo, which exhibit the multifunctional biological applications of the DNA-based self-assemblies.
authors.affiliation: State Key Lab of Food Science and Technology, International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
authors.forename: Maozhong
authors.initials: M
authors.lastname: Sun
authors.affiliation: State Key Lab of Food Science and Technology, International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
authors.forename: Liguang
authors.initials: L
authors.lastname: Xu
authors.affiliation: State Key Lab of Food Science and Technology, International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.affiliation: State Key Lab of Food Science and Technology, International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Wu
authors.affiliation: State Key Lab of Food Science and Technology, International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
authors.forename: Hua
authors.initials: H
authors.lastname: Kuang
authors.affiliation: State Key Lab of Food Science and Technology, International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
authors.forename: Libing
authors.initials: L
authors.lastname: Wang
authors.affiliation: State Key Lab of Food Science and Technology, International Joint Research Laboratory for Biointerface and Biodetection, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
authors.forename: Chuanlai
authors.initials: C
authors.lastname: Xu
mesh_terms: D000179:Acrylates / Q000737:chemistry; D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D002735:Chlorophyllides; D005095:Exoribonucleases / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D007259:Infrared Rays; D051379:Mice; D008819:Mice, Nude; D053758:Nanoparticles / Q000737:chemistry; D043942:Nanotubes / Q000737:chemistry* / Q000633:toxicity; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D010789:Phototherapy; D011137:Polystyrenes / Q000737:chemistry; D011166:Porphyrins / Q000737:chemistry / Q000627:therapeutic use / Q000633:toxicity; D011838:Radiation-Sensitizing Agents / Q000737:chemistry / Q000627:therapeutic use / Q000633:toxicity; D014057:Tomography, X-Ray Computed; D014183:Transplantation, Heterologous
chemical_list: D000179:Acrylates; D002735:Chlorophyllides; D011137:Polystyrenes; D011166:Porphyrins; D011838:Radiation-Sensitizing Agents; C509855:poly(styrene-b-acrylic acid); C062985:phytochlorin; D006046:Gold; D005095:Exoribonucleases; C065486:oligonucleotidase
keywords: core-satellite; multimodal imaging; nanorods; phototherapy; self-assembly; upconversion nanoparticles