title: Mediators of Treatment Effects in a Randomized Clinical Trial of Multisystemic Therapy-Health Care in Adolescents With Poorly Controlled Asthma: Disease Knowledge and Device Use Skills.
abstract: Determine whether Multisystemic Therapy-Health Care (MST-HC) improved asthma knowledge and controller device use skills among African-American youth with poorly controlled asthma and whether any improvements mediated changes in illness management.
  
  
  
  A randomized controlled trial was conducted with 170 adolescents with moderate to severe asthma. Families were randomized to MST-HC or attention control. Data were collected at baseline and 6 and 12 months after intervention completion.
  
  
  
  In linear mixed models, adolescents in the MST-HC group had increases in asthma knowledge; asthma knowledge was unchanged for attention control. Controller device use skills increased for adolescents in the MST-HC group, while skills declined for attention control. Both knowledge and skills mediated the relationship between intervention condition and changes in illness management.
  
  
  
  Tailored, home-based interventions that include knowledge and skills building components are one means by which illness management in African-American youth with poorly controlled asthma can be improved.
authors.affiliation: Carman and Ann Adams Department of Pediatrics, Wayne State University dellis@med.wayne.edu.
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Ellis
authors.affiliation: Carman and Ann Adams Department of Pediatrics, Wayne State University.
authors.forename: Pamela
authors.initials: P
authors.lastname: King
authors.affiliation: Carman and Ann Adams Department of Pediatrics, Wayne State University.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Naar-King
mesh_terms: D000293:Adolescent; D001741:Black or African American; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000208:ethnology / Q000628:therapy*; D001521:Behavior Therapy; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D007722:Health Knowledge, Attitudes, Practice; D006699:Home Care Services; D006801:Humans; D016014:Linear Models; D008297:Male; D010349:Patient Compliance / Q000208:ethnology / Q000706:statistics & numerical data; D012648:Self Care; D012944:Social Support; D016896:Treatment Outcome
chemical_list: D018927:Anti-Asthmatic Agents
keywords: adherence; asthma; family therapy