title: Multiple sclerosis and infections.
abstract: The intersection between infections and multiple sclerosis (MS) is complex and bidirectional. Numerous infectious agents have been posited to play a role in the initiation of MS, while emerging evidence suggests a potential relationship between established MS and the gut microbiome. As both systemic and CNS infections are major complications of MS, the clinical manifestations and evolving epidemiology of these infections over the lifespan of the MS patient are examined in this review. Data from animal models and human studies are discussed.
authors.affiliation: Division of Neuroimmunology & Neuroinfectious Diseases, Johns Hopkins Hospital, 600 North Wolfe Street, Meyer 6-113, Baltimore, MD 21287, USA.
authors.forename: Arun
authors.initials: A
authors.lastname: Venkatesan
mesh_terms: D000818:Animals; D006801:Humans; D007239:Infections / Q000150:complications*; D009103:Multiple Sclerosis / Q000209:etiology*
keywords: infections; multiple sclerosis; review