title: Evolution of regional oxygen saturation in the peri-operative of thoracic surgery and its relationship with central venous saturation.
abstract: OBJECTIVE
  To study the relationship between the values of SvcO2 and SrcO2 in lung resection with one lung ventilation (OLV) and changes in these variables and mean arterial pressure (MAP) and arterial oxygen saturation (SpO2) during the perioperative period.
  
  
  METHODS
  Prospective, observational study of 25 patients in whom pulmonary resection was performed with OLV. The values of MAP, SpO2, SvO2, and SrcO2 were recorded at 6 different times: 1)baseline; 2)double-lung ventilation before the OLV (VBP1); 3)during OLV; 4)after double-lung ventilation (VBP2); 5)30minutes after surgery, and 6)6hours after surgery.
  
  
  RESULTS
  The SrcO2 showed a significant increase from baseline to starting ventilation (65.72±9.05% vs 70.44±7.24%; P<.01). There were no significant changes in their values at the different intraoperative times. Post-operatively, as in the case of the SvcO2, a significant decrease (P<.001) of its value compared with the previous value was observed.
  
  
  CONCLUSIONS
  SrcO2 showed a significant increase after induction of anaesthesia and initiation of mechanical ventilation compared to baseline, and a significant decrease at the end of surgery after extubation in the immediate postoperative period. Being a tissue monitoring, non-invasive technique and with continuous values it can alert the clinician of changes in the ratio of oxygen consumption (VO2) to oxygen delivery (DO2) at times of greatest risk, such as OLV, extubation, and the early postoperative period.
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapia del Dolor, Hospital Universitario de La Princesa, Madrid, España.
authors.forename: F
authors.initials: F
authors.lastname: Ramasco
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapia del Dolor, Hospital Universitario de La Princesa, Madrid, España. Electronic address: rosamen2004@hotmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Méndez
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapia del Dolor, Hospital Universitario de La Princesa, Madrid, España.
authors.forename: A
authors.initials: A
authors.lastname: Planas
authors.affiliation: Unidad de Apoyo Metodológico, Hospital Universitario de La Princesa, Madrid, España.
authors.forename: L
authors.initials: L
authors.lastname: Vega
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapia del Dolor, Hospital Universitario de La Princesa, Madrid, España.
authors.forename: A
authors.initials: A
authors.lastname: Gómez
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapia del Dolor, Hospital Universitario de La Princesa, Madrid, España.
authors.forename: S
authors.initials: S
authors.lastname: Santidrián
mesh_terms: D006801:Humans; D061810:One-Lung Ventilation; D010100:Oxygen / Q000032:analysis*; D011446:Prospective Studies; D012121:Respiration, Artificial; D012129:Respiratory Function Tests; D013903:Thoracic Surgery
chemical_list: D010100:Oxygen
keywords: Central venous oxygen saturation; Cerebral oxygen saturation; Cirugía torácica; Monitorización perioperatoria; One lung ventilation; Perioperative monitoring; Saturación cerebral de oxígeno; Saturación venosa central de oxígeno; Thoracic surgery; Ventilación unipulmonar