title: Effects of perioperative blood transfusion on the prognosis in hereditary and sporadic colon cancer.
abstract: We investigated the effects of perioperative blood transfusion in the prognosis of hereditary and sporadic colon cancer. There are 1075 colon cancer patients, including 936 sporadic colon cancer and 139 with hereditary colon cancer undergoing surgery at our hospital. All patients underwent 10 years of follow-up. In the sporadic group, mortality, local recurrence rate and distant metastases rate of transfused patients were significantly higher than non-transfused patients. The 10-year survival rates were significantly lower in patients receiving blood transfusions compared to non-transfused patients. In the hereditary group, mortality was higher in transfused patients compared to non-transfused patients.
authors.affiliation: a Department of Colorectal Surgery, The Fourth Affiliated Hospital of China Medical University , Shenyang , China .
authors.forename: Xiao-Xia
authors.initials: XX
authors.lastname: Li
authors.affiliation: b Department of Colorectal Surgery, Shenyang Coloproctology Hospital , Shenyang , China , and.
authors.forename: Jin
authors.initials: J
authors.lastname: Meng
authors.affiliation: a Department of Colorectal Surgery, The Fourth Affiliated Hospital of China Medical University , Shenyang , China .
authors.forename: Gong-Ping
authors.initials: GP
authors.lastname: Sun
authors.affiliation: a Department of Colorectal Surgery, The Fourth Affiliated Hospital of China Medical University , Shenyang , China .
authors.forename: Yuan-Xin
authors.initials: YX
authors.lastname: Tang
authors.affiliation: a Department of Colorectal Surgery, The Fourth Affiliated Hospital of China Medical University , Shenyang , China .
authors.forename: Gao-Feng
authors.initials: GF
authors.lastname: Liang
authors.affiliation: a Department of Colorectal Surgery, The Fourth Affiliated Hospital of China Medical University , Shenyang , China .
authors.forename: Mo-Fei
authors.initials: MF
authors.lastname: Wang
authors.affiliation: c School of Public Health, China Medical University , Shenyang , China.
authors.forename: Xiao-Bo
authors.initials: XB
authors.lastname: Lu
mesh_terms: D000328:Adult; D000368:Aged; D001803:Blood Transfusion / Q000379:methods*; D003110:Colonic Neoplasms / Q000401:mortality / Q000601:surgery* / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D017063:Outcome Assessment, Health Care / Q000379:methods / Q000706:statistics & numerical data; D059035:Perioperative Period; D011379:Prognosis; D016016:Proportional Hazards Models; D015996:Survival Rate; D013997:Time Factors
keywords: Allogeneic red blood cell transfusion; colon cancer; hereditary colon cancer; mortality; perioperative blood transfusion; prognosis survival; sporadic colon cancer