title: Adrenal Tumors in Adults.
abstract: Although most adrenal tumors are not diagnostic dilemmas, there are cases that are challenging. This may be due to the tissue provided, for example fragmented tissue received in the setting of morcellation, or it may be due to inherently challenging histology, such as in cases with equivocal features of malignancy. Additionally, much has been learned about the molecular alterations of adrenal tumors, especially pheochromocytomas. Many of these alterations represent germline mutations with significant clinical implications for patients and their families. The aim of this review is to provide an overview of the most common adrenal tumors in adults so that pathologists can tackle these interesting tumors.
authors.affiliation: Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
authors.forename: Andre
authors.initials: A
authors.lastname: Pinto
authors.affiliation: Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: jbarletta@partners.org.
authors.forename: Justine A
authors.initials: JA
authors.lastname: Barletta
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology; D018246:Adrenocortical Adenoma / Q000175:diagnosis / Q000473:pathology; D018268:Adrenocortical Carcinoma / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D033162:Incidental Findings; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis / Q000473:pathology; D010673:Pheochromocytoma / Q000175:diagnosis / Q000473:pathology
keywords: Adrenal; Adrenal adenoma; Adrenocortical carcinoma; Pheochromocytoma