title: Using complex networks towards information retrieval and diagnostics in multidimensional imaging.
abstract: We present a fresh and broad yet simple approach towards information retrieval in general and diagnostics in particular by applying the theory of complex networks on multidimensional, dynamic images. We demonstrate a successful use of our method with the time series generated from high content thermal imaging videos of patients suffering from the aqueous deficient dry eye (ADDE) disease. Remarkably, network analyses of thermal imaging time series of contact lens users and patients upon whom Laser-Assisted in situ Keratomileusis (Lasik) surgery has been conducted, exhibit pronounced similarity with results obtained from ADDE patients. We also propose a general framework for the transformation of multidimensional images to networks for futuristic biometry. Our approach is general and scalable to other fluctuation-based devices where network parameters derived from fluctuations, act as effective discriminators and diagnostic markers.
authors.affiliation: Bose Institute, 93/1 Acharya PC Roy Road, Kolkata 700 009, India.
authors.forename: Soumya Jyoti
authors.initials: SJ
authors.lastname: Banerjee
authors.affiliation: Department of Biochemistry, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700 019, India.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Azharuddin
authors.affiliation: Regional Institute of Ophthalmology, Calcutta Medical College and Hospital, Kolkata 700 073, India.
authors.forename: Debanjan
authors.initials: D
authors.lastname: Sen
authors.affiliation: Regional Institute of Ophthalmology, Calcutta Medical College and Hospital, Kolkata 700 073, India.
authors.forename: Smruti
authors.initials: S
authors.lastname: Savale
authors.affiliation: Regional Institute of Ophthalmology, Calcutta Medical College and Hospital, Kolkata 700 073, India.
authors.forename: Himadri
authors.initials: H
authors.lastname: Datta
authors.affiliation: Department of Biochemistry, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700 019, India.
authors.forename: Anjan Kr
authors.initials: AK
authors.lastname: Dasgupta
authors.affiliation: Bose Institute, 93/1 Acharya PC Roy Road, Kolkata 700 009, India.
authors.forename: Soumen
authors.initials: S
authors.lastname: Roy
mesh_terms: D015352:Dry Eye Syndromes / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male