title: Epithelioid Glomus Tumor of the Uterine Cervix: A Case Report and Review.
abstract: Herein, we report a case of epithelioid glomus tumor involving the uterine cervix. A 67-yr-old woman with a long-standing history of cervical dysplasia underwent cervical conization. In addition to the patient's high-grade squamous intraepithelial lesion, histologic examination demonstrated an incidental, 0.2-cm glomus tumor in the cervical submucosa. The tumor was composed of bland epithelioid cells in scattered nests closely associated with small-caliber blood vessels. Immunohistochemically, the tumor cells were diffusely positive for smooth muscle actin and caldesmon and only focally positive for desmin and CD34. To our knowledge, only 2 similar case reports exist in the literature. The present case is the first cervical case seen with epithelioid features and in association with cervical dysplasia.
authors.affiliation: Departments of Pathology and Laboratory Medicine (J.T.A., J.E.B.)Obstetrics and Gynecology (S.H.K.), Pennsylvania Hospital, Philadelphia, Pennsylvania.
authors.forename: Jason T
authors.initials: JT
authors.lastname: Aynardi
authors.forename: Sarah H
authors.initials: SH
authors.lastname: Kim
authors.forename: Julieta E
authors.initials: JE
authors.lastname: Barroeta
mesh_terms: D000368:Aged; D002584:Cervix Uteri / Q000473:pathology*; D019092:Conization; D005260:Female; D005918:Glomus Tumor / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D065310:Squamous Intraepithelial Lesions of the Cervix / Q000175:diagnosis* / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis* / Q000473:pathology