title: [Prevalence of chronic complications in patients with over 30-year history of type 1 diabetes depending on the age of onset of diabetes].
abstract: The aim of this study was to evaluate the prevalence of chronic complications in patients with type 1 diabetes with more than 30 years of history of the disease, depending on the age of onset of diabetes. The criterion for inclusion in the study was over 30-year history of type 1 diabetes. The study group was divided into two subgroups according to the age of diagnosis of type 1 diabetes (either before or after 18 years of age). Anthropometric parameters, degree of metabolic control and the presence of markers of chronic diabetic micro- and macrovascular complications were assessed. The study was performed in 215 type 1 diabetic patients with more than 30 years history of the disease, aged 54±10 years, 98 men, 117 women. In 110 patients (group I), type 1 diabetes was diagnosed before age of 18 years, in 105 patients (group II) after 18 years of age. Patients in group I were younger, with a longer duration of the disease, more often treated with intensive functional insulin. There were no differences in terms of metabolic control between the assessed groups. Patients in group I were significantly more often diagnosed with chronic diabetic kidney disease, in group II hypertension was more often observed.
  
  
  CONCLUSIONS
  The diagnosis of type 1 diabetes before or after the age of 18 had no significant effect on the lack of chronic complications. Patients with diabetes diagnosed in childhood, after 30 years of disease, presented a higher incidence of diabetic kidney disease.
authors.affiliation: Katedra i Klinika Chorób Wewnętrznych i Diabetologii, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu.
authors.forename: Dorota
authors.initials: D
authors.lastname: Pisarczyk-Wiza
authors.affiliation: Katedra i Klinika Chorób Wewnętrznych i Diabetologii, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu.
authors.forename: Dorota
authors.initials: D
authors.lastname: Zozulińska-Ziółkiewicz
authors.affiliation: Katedra i Klinika Chorób Wewnętrznych i Diabetologii, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu.
authors.forename: Stanisław
authors.initials: S
authors.lastname: Piłaciński
authors.affiliation: Katedra i Klinika Chorób Wewnętrznych i Diabetologii, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Milcarek
authors.affiliation: Katedra i Klinika Chorób Wewnętrznych i Diabetologii, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu.
authors.forename: Bogna
authors.initials: B
authors.lastname: Wierusz-Wysocka
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000453:epidemiology; D003928:Diabetic Nephropathies / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D055815:Young Adult
keywords: chronic complications; long-term type 1 diabetes