title: Wound Complications after Laparotomy for Endometrial Cancer.
abstract: This study was conducted to determine the incidence of wound complications after laparotomy for endometrial cancer and significant predictors of risks. Medical records of patients with endometrial cancer undergoing laparotomy for surgical staging at Srinagarind Hospital, Khon Kaen University between January 2007 and December 2013 were reviewed. Intravenous antibiotic prophylaxis was routinely given 30 minutes before surgery. The primary endpoint was wound complications (including seroma, hematoma, separation, or infection) requiring additional medical and/or surgical management within 4 weeks of laparotomy. During the study period, 357 patients with complete medical records were reviewed. The mean age was 56.9 years. Wound complications were observed in 28 patients (7.84%, 95% CI, 5.27% to 11.14%). Body mass index (BMI) ≥ 30 kg/m2, diabetes mellitus (DM), and prior abdominal surgery were observed as significant independent factors predicting an increased risk of wound complications with adjusted odds ratios (95% CIs) of 2.96 (1.23-7.16), 2.43 (1.06-5.54), and 3.05 (1.03-8.98), respectively. In conclusion, the incidence of wound complications after laparotomy for endometrial cancer was 7.8%. Significant independent predictors of risk included BMI, DM and prior abdominal surgery.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand E-mail : kiet_ji@hotmail.com.
authors.forename: Wilasinee
authors.initials: W
authors.lastname: Nhokaew
authors.forename: Amornrat
authors.initials: A
authors.lastname: Temtanakitpaisan
authors.forename: Pilaiwan
authors.initials: P
authors.lastname: Kleebkaow
authors.forename: Bundit
authors.initials: B
authors.lastname: Chumworathayi
authors.forename: Sanguanchoke
authors.initials: S
authors.lastname: Luanratanakorn
authors.forename: Chumnan
authors.initials: C
authors.lastname: Kietpeerakool
mesh_terms: D015992:Body Mass Index; D016889:Endometrial Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D007813:Laparotomy / Q000009:adverse effects*; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D013785:Thailand; D014945:Wound Healing / Q000502:physiology