title: Intraocular Pressure After 2 Hours of Small-Diameter Scleral Lens Wear.
abstract: OBJECTIVE
  Compression of episcleral veins or deformation of tissue in the Schlemm's canal beneath the landing zone of scleral lenses could elevate intraocular pressure (IOP). We examined the effect of 2 hr of small-diameter scleral lens wear on IOP.
  
  
  METHODS
  Twenty-nine participants, 29 ± 6 years old (mean ± SD) who experienced no history of eye disease or scleral lens wear, were included in the study. Each participant was fitted with a 15-mm Jupiter scleral lens on one eye (study eye). Intraocular pressure was measured in both eyes by pneumatonometry centrally on the cornea and peripherally on the sclera. The lens was then placed on one eye and was worn for 2 hr. Intraocular pressure was remeasured immediately after lens placement, at 1 and 2 hr of lens wear, and immediately after lens removal. Intraocular pressure after removal of the scleral lens was compared with IOP before placing the lens and to IOP in the control eye using paired t tests.
  
  
  RESULTS
  Immediately after removing the scleral lens, mean central IOP in the study eye (13.9 ± 3.1 mm Hg) was not different from mean central IOP in the control eye (13.5 ± 2.2 mm Hg, P = 0.4) or in the same eye before lens wear (13.6 ± 1.9 mm Hg, P = 0.6). There were also no differences in IOP measured peripherally at 2 hr of lens wear (P = 0.8).
  
  
  CONCLUSIONS
  Neophyte scleral lens wear of a 15-mm scleral lens for 2 hr does not increase IOP in healthy eyes.
authors.affiliation: Department of Ophthalmology, Mayo Clinic, Rochester, MN.
authors.forename: Cherie B
authors.initials: CB
authors.lastname: Nau
authors.forename: Muriel M
authors.initials: MM
authors.lastname: Schornack
authors.forename: Jay W
authors.initials: JW
authors.lastname: McLaren
authors.forename: Arthur J
authors.initials: AJ
authors.lastname: Sit
mesh_terms: D000328:Adult; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D011474:Prosthesis Design; D012590:Sclera / Q000502:physiology*; D013997:Time Factors; D014065:Tonometry, Ocular / Q000379:methods; D055815:Young Adult