title: Characterization of the Acute Inflammatory Response in Measles Infection.
abstract: Among 167 hospitalized children with measles, circulating concentrations of interleukin (IL)-6, IL-1β, IL-1Ra, IL-4, interferon (IFN)-α, IFN-β, and T helper-17 cytokines were low, whereas leukopenia, increased lactate dehydrogenase, IL-18, and IFN-γ concentrations characterized the inflammatory response. In addition to understanding measles-induced immunologic responses, this profile may assist in differential diagnosis.
authors.affiliation: Department of Internal Medicine, Radboud University Nijmegen Medical Centre, and Nijmegen Institute for Infection, Inflammation and Immunity (N4i), The Netherlands.
authors.forename: Jaap
authors.initials: J
authors.lastname: Ten Oever
authors.affiliation: Department of Internal Medicine, Radboud University Nijmegen Medical Centre, and Human Genomics Laboratory, University of Medicine and Pharmacy of Craiova.
authors.forename: Anca
authors.initials: A
authors.lastname: Riza
authors.affiliation: Department of Infectious Diseases, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Mihaela
authors.initials: M
authors.lastname: Sabou
authors.affiliation: Department of Infectious Diseases, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Cristina
authors.initials: C
authors.lastname: Cismaru
authors.affiliation: Department of Internal Medicine, Radboud University Nijmegen Medical Centre, and Nijmegen Institute for Infection, Inflammation and Immunity (N4i), The Netherlands Department of Infectious Diseases, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Mihai G
authors.initials: MG
authors.lastname: Netea
authors.affiliation: Department of Infectious Diseases, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Adriana
authors.initials: A
authors.lastname: Slavcovici
keywords: inflammatory response; interferon-γ; interleukin-18; measles; oral candidiasis