title: Lichen planus of the lower limbs: successful treatment with psoralen cream plus ultraviolet A photochemotherapy.
abstract: Lichen planus (LP) classifies into different subtypes depending on morphology and localization. Localized LP of the lower limb (LPLL) manifests a great challenge due to persistent itching, therapeutic resistance and the risk to develop into SCC. We report two cases with LPLL refractory to standard topical therapy, which were successfully treated with psoralen cream plus UVA photochemotherapy (cream-PUVA). We propose cream-PUVA as an alternative therapeutic option effective for localized LP of the lower limbs.
authors.affiliation: Department of Dermatology and Allergology, Munich, Germany.
authors.forename: Adel
authors.identifier: http://orcid.org/0000-0002-3818-5384
authors.initials: A
authors.lastname: Alsenaid
authors.affiliation: Department of Dermatology and Allergology, Munich, Germany.
authors.forename: Ali
authors.initials: A
authors.lastname: Alamri
authors.affiliation: Department of Dermatology and Allergology, Munich, Germany.
authors.forename: Jörg C
authors.initials: JC
authors.lastname: Prinz
authors.affiliation: Department of Dermatology and Allergology, Munich, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Ruzicka
authors.affiliation: Department of Dermatology and Allergology, Munich, Germany.
authors.forename: Ronald
authors.initials: R
authors.lastname: Wolf
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy* / Q000473:pathology; D035002:Lower Extremity; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy / Q000379:methods*; D011537:Pruritus / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome
keywords: PUVA; SCC; cream-PUVA; hypertrophic lichen planus; lichen planus; phototherapy