title: [When muscle relaxants have unexpected prolonged duration during anaesthesia].
abstract: Muscle relaxation facilitates tracheal intubation and improves surgical conditions during anaesthesia. However, unexpected prolonged muscle relaxation may occur. This article describes important causes of prolonged muscle relaxation and gives suggestions for its prevention. Drug interactions, incomplete reversal, co-morbidity, inaccurate neuromuscular monitoring and critical illness may prolong the effect of muscle relaxants. The anaesthetist must titrate the muscle relaxants using objective neuromuscular monitoring and proper reversal of the blockade when needed.
authors.affiliation: matias.vested.madsen@regionh.dk.
authors.forename: Matias Vested
authors.initials: MV
authors.lastname: Madsen
authors.forename: Emilie
authors.initials: E
authors.lastname: Øberg
authors.forename: Jacob
authors.initials: J
authors.lastname: Rosenberg
authors.forename: Mona Ring
authors.initials: MR
authors.lastname: Gätke
mesh_terms: D000762:Anesthesia Recovery Period; D004347:Drug Interactions; D006801:Humans; D019148:Neuromuscular Blockade / Q000009:adverse effects; D009466:Neuromuscular Blocking Agents / Q000009:adverse effects / Q000037:antagonists & inhibitors / Q000493:pharmacokinetics*; D061886:Neuromuscular Monitoring; D013997:Time Factors
chemical_list: D009466:Neuromuscular Blocking Agents