title: [Comparative study of laparoscopic and open surgery for gastric gastrointestinal stromal tumors].
abstract: OBJECTIVE
  To investigate the feasibility and short-term efficacy of laparoscopic resection of primary localized gastric gastrointestinal stromal tumors (GIST) by comparing with open surgery.
  
  
  METHODS
  Clinicopathological data of 167 gastric GIST patients undergoing operation in Zhongshan Hospital from June 2008 to December 2013 were retrospectively analyzed, among whom 55 received laparoscopic surgery and 112 underwent open surgery for primary local gastric GIST. Efficacy of different size and different location of GIST was compared between laparoscopic and open groups.
  
  
  RESULTS
  There was no conversion to open surgery in laparoscopy group. Compared with open surgery, laparoscopic resection for gastric GIST smaller than 5 cm or located at anterior wall, greater curvature, lesser curvature, was associated with similar operation time(P>0.05), but less blood loss, shorter post-hospital stay or flatus time(all P<0.05). The operative outcomes were similar between laparoscopic and open resection for gastric GIST bigger than or equal to 5 cm or located at posterior wall(all P>0.05), except the longer operation time in laparoscopy group(P<0.05). The incidence of postoperative complication did not differ between two groups. Laparoscopic group had 2 patients with gastroparesis and open group had 2 gastroparesis, 2 pulmonary infection, and 1 poor wound healing(all P>0.05), which all recovered after conservative treatment. During 7 to 84 months(median 35) of follow-up, no recurrence or hepatic metastasis was found in laparoscopy group, and 3 hepatic metastases in open group. There was no significant difference of recurrence-free survival between two groups(P>0.05).
  
  
  CONCLUSIONS
  Laparoscopic resection for gastric GIST is safe and effective in selected patients, especially for those with tumors smaller than 5 cm, or located at anterior wall, greater curvature, lesser curvature, whose short-term outcomes are better than open resection.
authors.affiliation: Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China. shen.kuntang@zs-hospital.sh.cn.
authors.forename: Anwei
authors.initials: A
authors.lastname: Xue
authors.forename: Yongbin
authors.initials: Y
authors.lastname: Fu
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Gao
authors.forename: Yong
authors.initials: Y
authors.lastname: Fang
authors.forename: Ping
authors.initials: P
authors.lastname: Shu
authors.forename: Jiaqian
authors.initials: J
authors.lastname: Lin
authors.forename: Yingyong
authors.initials: Y
authors.lastname: Hou
authors.forename: Kuntang
authors.initials: K
authors.lastname: Shen
authors.forename: Jing
authors.initials: J
authors.lastname: Qin
authors.forename: Yihong
authors.initials: Y
authors.lastname: Sun
authors.forename: Xinyu
authors.initials: X
authors.lastname: Qin
mesh_terms: D005743:Gastrectomy / Q000379:methods*; D046152:Gastrointestinal Stromal Tumors / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D007902:Length of Stay; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000601:surgery*; D016896:Treatment Outcome