title: A novel 10-hydroxycamptothecin-glucoside from the fruit of Camptotheca acuminata.
abstract: Glycosides were isolated from the fruit of Camptotheca acuminata and identified using NMR, MS, UV and IR spectrometries. 10-O-(1-β-D-glycosyl) camptothecin (1) was identified for the first time in a natural material. In addition, compounds 2-4 were firstly reported from the fruits of C. acuminata and indentified as syringaresinol-4, 4'-O-bis-β-D-glucoside (2), hyperoside (3) and pumiloside (4), respectively. Two known compounds, vincoside-lactam (5) and strictosidinic acid (6), were also obtained.
authors.affiliation: a Department of Pharmaceutical Technology , College of Biological Engineering, Wuhan Polytechnic , Wuhan , China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Guo
authors.affiliation: a Department of Pharmaceutical Technology , College of Biological Engineering, Wuhan Polytechnic , Wuhan , China.
authors.forename: Qiaoyu
authors.initials: Q
authors.lastname: Yuan
mesh_terms: D029769:Camptotheca / Q000737:chemistry*; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry*; D002241:Carbohydrates / Q000032:analysis; D002243:Carbolines / Q000032:analysis; D005638:Fruit / Q000737:chemistry*; D005663:Furans / Q000032:analysis; D005960:Glucosides; D006027:Glycosides / Q000032:analysis; D006868:Hydrolysis; D017705:Lignans / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D011794:Quercetin / Q000031:analogs & derivatives / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: C000611787:10-O-(1-beta-D-glycosyl)camptothecin; D002241:Carbohydrates; D002243:Carbolines; D005663:Furans; D005960:Glucosides; D006027:Glycosides; D017705:Lignans; C530309:pumiloside; C551725:strictosidinic acid; C042192:syringaresinol; C021304:hyperoside; D011794:Quercetin; C028098:10-hydroxycamptothecin; D002166:Camptothecin
keywords: 10-O-(1-β-D-glycosyl) camptothecin; Camptotheca acuminata; glycoside; syringaresinol-4, 4′-O-bis-β-D-glucoside