title: Prognosis of patients with coronary artery disease treated in different therapy units at department of cardiology: a retrospective cohort study.
abstract: BACKGROUND
  Coronary artery disease (CAD) is a major health problem in global. Benefit from different care unit for various type of CAD is remaining unknown. We investigate if coronary care unit (CCU) reduces the incidence of major adverse cardiovascular events (MACEs).
  
  
  METHODS
  806 CAD patients including stable angina (SA) and acute coronary syndrome (ACS) who treated in department of cardiology were involved in the study as two groups. Each group involved two subgroups according to the therapy unit including CCU and normal unit. 12-48 months follow-up was carried out. The primary end point was all cause mortality.
  
  
  RESULTS
  For SA, death from any cause occurred in 1.0% of the patients in the normal group (1 of 108), as compared with 5.1% in the CCU group (3 of 59) (hazard ratio [HR], 0.164; 95% confidence interval [CI], 0.017 to 1.580; P=0.118). Kaplan-Meier survival analysis showed that there were no significant differences between the two subgroups with respect to the risk of death (P=0.074), revascularization (P=0.660), stroke (P=0.497), heart failure (P=0.658) and hemorrhage (P=0.096). For ACS, death occurred in 1.9% of the patients in the normal subgroup (5 of 267), as compared with 1.3% in the CCU subgroup (5 of 372) (HR, 1.403; 95% CI, 0.406-4.846; P=0.593). Kaplan-Meier survival analysis showed that there were no significant differences between the two subgroups with respect to the risk of death (P=0.591), revascularization (P=0.996), stroke (P=0.425), heart failure (P=0.625).
  
  
  CONCLUSIONS
  CAD patients treated in CCU obtain little benefits compared with normal.
authors.affiliation: Department of Cardiology, Zhong Da Hospital Affiliated to Southeast University Nanjing, Jiangsu, China.
authors.forename: Cong
authors.initials: C
authors.lastname: Fu
authors.affiliation: Department of Cardiology, Zhong Da Hospital Affiliated to Southeast University Nanjing, Jiangsu, China.
authors.forename: Yuyu
authors.initials: Y
authors.lastname: Yao
authors.affiliation: Department of Cardiology, Zhong Da Hospital Affiliated to Southeast University Nanjing, Jiangsu, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Cardiology, Jiang Yin Peoples' Hospital Jiangsu, China.
authors.forename: Chaojun
authors.initials: C
authors.lastname: Yu
authors.affiliation: Department of Cardiology, Zhong Da Hospital Affiliated to Southeast University Nanjing, Jiangsu, China.
authors.forename: Genshan
authors.initials: G
authors.lastname: Ma
keywords: Coronary artery disease; coronary care unit; outcomes