title: [A subacute dementia: Inflammatory cerebral amyloid angiopathy].
abstract: We report a case of inflammatory cerebral amyloid angiopathy (CAA) that led to rapid cognitive decline, seizures, visual hallucinations, hyperproteinorrachia and right hemispheric leukopathy. Brain biopsy gave the diagnosis of CAA. Although no inflammatory infiltrate was found in the biopsy sample, corticosteroids led to a regression of the radiological lesions without significant clinical improvement. CAA is a rare disease, defined by lesions of classical cerebral amyloid angiopathy and perivascular infiltrates in contact with the affected vessels. In cases of rapidly progressive dementia associated with leukopathy, inflammatory amyloid angiopathy should be considered as cognitive disorders may improve after immunosuppressive therapy.
authors.affiliation: CHRU Cavale-Blanche, boulevard Tanguy-Prigent, 29200 Brest, France. Electronic address: sophia_charef@hotmail.fr.
authors.forename: S
authors.initials: S
authors.lastname: Charef
authors.affiliation: CHRU Cavale-Blanche, boulevard Tanguy-Prigent, 29200 Brest, France.
authors.forename: A
authors.initials: A
authors.lastname: Leblanc
authors.affiliation: CHRU Morvan, 2, avenue Floch, 29200 Brest, France.
authors.forename: B
authors.initials: B
authors.lastname: Guibourg
authors.affiliation: CHRU Morvan, 2, avenue Floch, 29200 Brest, France.
authors.forename: I
authors.initials: I
authors.lastname: Quintin-Roue
authors.affiliation: CHRU Cavale-Blanche, boulevard Tanguy-Prigent, 29200 Brest, France.
authors.forename: D
authors.initials: D
authors.lastname: Ben Salem
authors.affiliation: CHRU Cavale-Blanche, boulevard Tanguy-Prigent, 29200 Brest, France.
authors.forename: F
authors.initials: F
authors.lastname: Zagnoli
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000369:Aged, 80 and over; D001706:Biopsy; D016657:Cerebral Amyloid Angiopathy / Q000473:pathology* / Q000523:psychology; D003072:Cognition Disorders / Q000209:etiology / Q000523:psychology; D003704:Dementia / Q000473:pathology* / Q000523:psychology; D018450:Disease Progression; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents
keywords: Angiopathie amyloïde cérébrale; Cerebral amyloid angiopathy; Dementia; Démence; Inflammation; Leucopathie; Leukopathy