title: [Endoscopic submucosal dissection in early gastric cancer: Experience in 16 patients].
abstract: BACKGROUND
  Endoscopic submucosal dissection (ESD) is a minimally invasive procedure that allows curative treatment of early gastric cancer (EGC) in selected patients.
  
  
  OBJECTIVE
  To report our initial experience with ESD.
  
  
  METHODS
  Analysis of prospective data from 16 patients aged 61 to 84 years, who underwent ESD between December 2011 and June 2014. Tumor type, operative time, hospitalization length, oncologic outcomes, complications and short-term follow up were registered.
  
  
  RESULTS
  En-block resection was achieved in all cases. The median operative time was 135 min (range: 50-320 min). Specimens' median size was 3.5 cm (range: 3-10). All the resections were R0. In 14 patients ESD was considered curative. In two patients, ESD was considered potentially non-curative due to the presence pathological risk factors for lymph-node metastases in the biopsy specimen. Both patients underwent laparoscopic gastrectomy with lymph-node dissection. There was one case of gastric wall perforation that was repaired by laparoscopic suture. There was no mortality. The median follow-up time was 15 months (range: 2-30 months).
  
  
  CONCLUSIONS
  ESD is a feasible and safe procedure in our institution with good results in this initial experience.
authors.forename: Andrés
authors.initials: A
authors.lastname: Donoso D
authors.forename: Allan
authors.initials: A
authors.lastname: Sharp
authors.forename: Adolfo
authors.initials: A
authors.lastname: Parra-Blanco
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Roa
authors.forename: Jean Phillipe
authors.initials: JP
authors.lastname: Bächler
authors.forename: Fernando
authors.initials: F
authors.lastname: Crovari
authors.forename: Ricardo
authors.initials: R
authors.lastname: Funke
authors.forename: Fernando
authors.initials: F
authors.lastname: Pimentel
authors.forename: Luis
authors.initials: L
authors.lastname: Ibáñez
authors.forename: Sergio
authors.initials: S
authors.lastname: Guzmán
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D018572:Disease-Free Survival; D004210:Dissection / Q000379:methods*; D055088:Early Detection of Cancer; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods*; D005753:Gastric Mucosa / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D061646:Operative Time; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome