title: [Therapeutic Effect of Autologous Platelet-rich Gel in the Treatment of Chronic Skin Ulcer with Tophus].
abstract: OBJECTIVE
  To evaluate the clinical effectiveness and safety of autologous platelet-rich gel (APG) in the treatment of chronic skin ulcer with tophus.
  
  
  METHODS
  Four patients of chronic skin ulcer with tophus received routine debridement to remove necrotic tissue and erasion tophus as far as possible,and then received the treatment of APG.
  
  
  RESULTS
  All of the patients had their wounds healed after the treatment of APG (one wound was treated twice). The wounds were healed between 8 to 22 d, average (13. 7±6. 8) d, while there were no adverse effects observed.
  
  
  CONCLUSIONS
  Topical therapy with APG may be considered as an effective and safe adjuvant method for the treamtment of chronic skin ulcer with tophus.
authors.forename: Zhi-hua
authors.initials: ZH
authors.lastname: Ai
authors.forename: Yong
authors.initials: Y
authors.lastname: Wan
authors.forename: Jun-jing
authors.initials: JJ
authors.lastname: Liu
authors.forename: Hong-mei
authors.initials: HM
authors.lastname: Lang
authors.forename: Jie
authors.initials: J
authors.lastname: Xiao
authors.forename: Ning-na
authors.initials: NN
authors.lastname: Li
authors.forename: Ying
authors.initials: Y
authors.lastname: Cheng
authors.forename: Zhi-qing
authors.initials: ZQ
authors.lastname: You
mesh_terms: D001792:Blood Platelets; D002908:Chronic Disease; D005782:Gels; D006073:Gout / Q000150:complications; D006801:Humans; D053657:Platelet-Rich Plasma; D012883:Skin Ulcer / Q000628:therapy*; D014945:Wound Healing
chemical_list: D005782:Gels