title: Photodynamic hyperthermal chemotherapy with indocyanine green in feline vaccine-associated sarcoma.
abstract: The anticancer effects of photodynamic hyperthermal chemotherapy (PHCT), which consists of a combination of indocyanine green photodynamic hyperthermal therapy and local chemotherapy, have previously been reported. The present study investigated the effect of PHCT in six cases of feline vaccine-associated sarcoma (FVAS) following conservative surgical resection. No recurrence was observed in three out of six (50%) cases, while recurrence was observed in the remaining three cases. Of note, each feline with recurrences had previously undergone surgical resection more than three times, whereas those without recurrence had undergone no or one previous resection. In addition, the three animals in which there was no recurrence survived between 893 and 1,797 days following surgery. In conclusion, the results of the present study suggested that PHCT may be a candidate as a novel adjuvant cancer therapy for FVAS.
authors.affiliation: Onoyama Animal Hospital, Asago 669-5213, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Onoyama
authors.affiliation: Department of Clinical Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tsuka
authors.affiliation: Department of Clinical Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Imagawa
authors.affiliation: Department of Clinical Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Osaki
authors.affiliation: Department of Clinical Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Sugiyama
authors.affiliation: Department of Clinical Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Azuma
authors.affiliation: Department of Clinical Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
authors.forename: Norihiko
authors.initials: N
authors.lastname: Ito
authors.affiliation: Aino Animal Hospital, Fukuroi 437-0028, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Kawashima
authors.affiliation: Department of Clinical Medicine, School of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan.
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Okamoto
keywords: feline vaccine-associated sarcoma; indocyanine green; photodynamic hyperthermal chemotherapy