title: Radiation Recall Pneumonitis During Systemic Treatment With Everolimus.
abstract: Radiation recall syndrome is an acute inflammatory reaction developing at anatomical sites of previously irradiated tissue, weeks to months after the completion of radiation therapy. The distribution pattern of inflammation typically involves, and remains limited to, the boundaries of prior radiation treatment fields. Several classical chemotherapy drugs have been reported to have the potential for causing radiation recall syndrome. With the increasing availability and expanding use of novel biologic and targeted therapy anticancer drugs, isolated reports of radiation recall syndrome secondary to this class of agents are starting to appear in the literature. We describe a case of everolimus-induced radiation recall pneumonitis in a patient with metastatic renal cell cancer.
authors.affiliation: Saint Francis Cancer Treatment Center, Grand Island, NE, USA.
authors.forename: Douglas
authors.initials: D
authors.lastname: Clark
authors.forename: Dron
authors.initials: D
authors.lastname: Gauchan
authors.forename: Ryan
authors.initials: R
authors.lastname: Ramaekers
authors.forename: Max
authors.initials: M
authors.lastname: Norvell
authors.forename: Mehmet Sitki
authors.initials: MS
authors.lastname: Copur
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D003131:Combined Modality Therapy / Q000009:adverse effects; D000068338:Everolimus / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D017564:Radiation Pneumonitis / Q000139:chemically induced* / Q000175:diagnosis*; D011855:Radiodermatitis / Q000139:chemically induced / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D000068338:Everolimus