title: Recurrent Streptococcus Pneumoniae Meningitis in a Child with Split Hand and Foot Malformation and Undiagnosed Mondini Dysplasia.
abstract: Recurrent bacterial meningitis is a life-threatening infection of the central nervous system that is mostly connected with anatomical abnormalities of the skull, chronic parameningeal infections and immunodeficiencies. It's rarely seen, but when it occurs an extensive investigation should be carried out to discover the responsible factor, so that further episodes can be prevented. We report on a child with split hand and foot (SHFM), confirmed incorrect karyotype 46, XY, t(7:12)(q21.2;q21.3) and a fourth episode of fulminant meningitis caused by penicillin-resistantStreptococcus pneumoniae. After a broad evaluation of factors predisposing to recurrent meningitis, the undiagnosed malformation of his inner and middle ears - Mondini dysplasia was found. We suggest examining all children with SHFM for hearing impairment before they develop recurrent meningitis. The time when the radiological procedure for searching for inner ear dysplasia should be performed could be a controversial issue: before or after the first episode of meningitis. From the epidemiological point of view, high-resolution computer tomography scanning of the temporal bones should be considered after the diagnosis of deafness in a child with SHFM related to 7q21 deletion.
authors.affiliation: Department of Infectious Diseases and Child Neurology, Karol Marcinkowski University of Medical Sciences in Poznań, Szpitalna Street 27/33, 60-578 Poznań, Poland.
authors.forename: Mazur-Melewska
authors.initials: MM
authors.lastname: Katarzyna
authors.affiliation: Pediatric ENT Department, Karol Marcinkowski Poznan University of Medical Sciences, Poznań, Szpitalna Street 27/33, 60-578 Poznań, Poland.
authors.forename: Szydłowski
authors.initials: S
authors.lastname: Jarosław
authors.affiliation: Pediatric Radiology Department Chair of Radiology, Karol Marcinkowski University of Medical Sciences, Poznań, Szpitalna Street 27/33, 60-578 Poznań, Poland.
authors.forename: Jończyk-Potoczna
authors.initials: JP
authors.lastname: Katarzyna
authors.affiliation: Department of Infectious Diseases and Child Neurology, Karol Marcinkowski University of Medical Sciences in Poznań, Szpitalna Street 27/33, 60-578 Poznań, Poland.
authors.forename: Służewski
authors.initials: S
authors.lastname: Wojciech
authors.affiliation: Department of Infectious Diseases and Child Neurology, Karol Marcinkowski University of Medical Sciences in Poznań, Szpitalna Street 27/33, 60-578 Poznań, Poland.
authors.forename: Figlerowicz
authors.initials: F
authors.lastname: Magdalena
keywords: Mondini dysplasia; Recurrent meningitis; Split hand and foot malformation