title: Sustained benefits of autologous serum eye drops on self-reported ocular symptoms and vision-related quality of life in Australian patients with dry eye and corneal epithelial defects.
abstract: BACKGROUND
  This research examined the effect of autologous serum eye drops (ASED) on ocular symptoms, visual-related functioning and quality of life for patients failing other therapies.
  
  
  METHODS
  Patients (N = 77) were asked to complete a survey prior to ASED use, and 2 and 12 months post-treatment.
  
  
  RESULTS
  Significant improvements in symptom frequency and severity were documented for dryness, ocular pain and grittiness at 2 and 12 months. Patients felt more in control and required less help from others at 12 months.
  
  
  CONCLUSIONS
  ASED produce sustained benefits to dry eye symptoms, improve feelings of control and reduce requirements for assistance from others.
authors.affiliation: Clinical Services and Research, Australian Red Cross Blood Service, 17 O' Riordan Street, Alexandria, New South Wales, Australia.
authors.forename: Phillip
authors.initials: P
authors.lastname: Mondy
authors.affiliation: Clinical Services and Research, Australian Red Cross Blood Service, 17 O' Riordan Street, Alexandria, New South Wales, Australia.
authors.forename: Tania
authors.initials: T
authors.lastname: Brama
authors.affiliation: Clinical Services and Research, Australian Red Cross Blood Service, 17 O' Riordan Street, Alexandria, New South Wales, Australia.
authors.forename: Jenny
authors.initials: J
authors.lastname: Fisher
authors.affiliation: Clinical Services and Research, Australian Red Cross Blood Service, 417 St Kilda Rd, Melbourne, Victoria, Australia.
authors.forename: Carley N
authors.initials: CN
authors.lastname: Gemelli
authors.affiliation: Clinical Services and Research, Australian Red Cross Blood Service, 17 O' Riordan Street, Alexandria, New South Wales, Australia.
authors.forename: Karen
authors.initials: K
authors.lastname: Chee
authors.affiliation: Clinical Services and Research, Australian Red Cross Blood Service, 17 O' Riordan Street, Alexandria, New South Wales, Australia.
authors.forename: Anastazia
authors.initials: A
authors.lastname: Keegan
authors.affiliation: Clinical Services and Research, Australian Red Cross Blood Service, 17 O' Riordan Street, Alexandria, New South Wales, Australia. Electronic address: dawaller@redcrossblood.org.au.
authors.forename: Daniel
authors.initials: D
authors.lastname: Waller
mesh_terms: D000328:Adult; D000368:Aged; D001315:Australia; D003316:Corneal Diseases / Q000188:drug therapy*; D015352:Dry Eye Syndromes / Q000188:drug therapy*; D019573:Epithelium, Corneal / Q000378:metabolism / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000627:therapeutic use*; D011788:Quality of Life; D044967:Serum; D014785:Vision, Ocular / Q000187:drug effects*
chemical_list: D009883:Ophthalmic Solutions
keywords: Autologous serum eye drops; Dry eye syndrome; Quality of life