title: Influence of silicone oil tamponade on self-sealing sclerotomy using 25-gauge transconjunctival sutureless vitrectomy: a retrospective comparative study.
abstract: BACKGROUND
  Characteristic complications have been reported for transconjunctival sutureless vitrectomy, such as postoperative sclerotomy leakage and postoperative hypotony. Particular attention to sclerotomy closure is required in cases of silicone oil tamponade, because postoperative supplementation of silicone oil implies reoperation, whereas postoperative supplement of gas is comparatively easy. This study investigated sclerotomy closure in cases of silicone oil tamponade using 25-gauge transconjunctival sutureless vitrectomy.
  
  
  METHODS
  We enrolled 19 consecutive eyes with silicone oil injection (Group A, self-sealing sclerotomies, n = 10) (Group B, sutured sclerotomies, n = 9) and 10 eyes with silicone oil removal (Group C, self-sealing sclerotomies) using 25-gauge TSV. Postoperative intraocular pressure was compared between Groups A and B, and between Groups A and C using repeated-measures analysis of variance (ANOVA), one-way factorial ANOVA, and the Tukey-Kramer test.
  
  
  RESULTS
  No significant differences in age or axial length were seen among groups, but surgical time differed significantly between Group C and the other groups. Mean duration of silicone oil tamponade was 3.2 ± 1.4 months in Group C, and no sclerotomies in Group A or C required suture placement. Postoperative silicone oil leakage to the subconjunctival space was not encountered in Group A. No cases showed postoperative hypotony (defined as intraocular pressure <5 mmHg). Significant differences in intraocular pressure within the same postoperative period were not identified between Groups A and B. Conversely, significant differences in intraocular pressure within the same postoperative period were identified at postoperative days 1 and 2, although not at postoperative week 1 or postoperative month 1 between Groups A and C.
  
  
  CONCLUSIONS
  The procedure for sclerotomy closure seems to have little influence on postoperative intraocular pressure in eyes with silicone oil tamponade using 25-gauge transconjunctival sutureless vitrectomy, because silicone oil tamponade may avoid postoperative hypotony by decreasing sclerotomy leakage in the early postoperative period.
authors.affiliation: Department of Ophthalmology, National Hospital Organization Sagamihara Hospital, 18-1 Sakuradai, Minami-ku, Sagaminara, Kanagawa, 252-0392, Japan. two-shina@s7.dion.ne.jp.|Department of Ophthalmology, Jikei University School of Medicine, 3-19-18 Nishi-shinbashi Minato-ku, Tokyo, 105-8471, Japan. two-shina@s7.dion.ne.jp.
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Takashina
authors.affiliation: Department of Ophthalmology, Jikei University School of Medicine, 3-19-18 Nishi-shinbashi Minato-ku, Tokyo, 105-8471, Japan. akirawa@jikei.ac.jp.
authors.forename: Akira
authors.initials: A
authors.lastname: Watanabe
authors.affiliation: Department of Ophthalmology, Jikei University School of Medicine, 3-19-18 Nishi-shinbashi Minato-ku, Tokyo, 105-8471, Japan. tsuneh@jikei.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsuneoka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003228:Conjunctiva / Q000601:surgery*; D003930:Diabetic Retinopathy / Q000601:surgery; D058450:Endotamponade; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D012189:Retrospective Studies; D012599:Sclerostomy; D012827:Silicone Oils; D013529:Surgical Wound Dehiscence / Q000517:prevention & control; D013536:Suture Techniques; D014821:Vitrectomy / Q000379:methods*; D018630:Vitreoretinopathy, Proliferative / Q000601:surgery; D055815:Young Adult
chemical_list: D012827:Silicone Oils