title: Urticaria and Allergy-Mediated Conditions.
abstract: Urticaria is a common condition that involves pruritic, raised skin wheals. Although urticaria is a benign, self-limiting condition, it may cause frustration for patients, often because of its chronicity and its tendency to recur. It can also be a life-threatening allergic reaction. Diagnosis is made clinically. It affects 20% of the general population. The first-line treatment for nonremitting cases includes H-1anti-histamines. However, other therapies may be employed. Other allergy-mediated skin conditions include angioedema, contact dermatitis, and atopic dermatitis. Diagnosis is clinical, and management focuses on prevention, avoiding triggers, and treating the itching and inflammation that accompany these conditions.
authors.affiliation: Penn State Milton S. Hershey Medical Center, Department of Family and Community Medicine, 566 Dickens Drive, Hummelstown, Hershey, PA 17036, USA.
authors.forename: Lena
authors.initials: L
authors.lastname: Jafilan
authors.affiliation: Penn State Milton S. Hershey Medical Center, Department of Family and Community Medicine, 114 Stonebrook Drive, Palmyra, Hershey, PA 17078, USA. Electronic address: cjames3@hmc.psu.edu.
authors.forename: Charis
authors.initials: C
authors.lastname: James
mesh_terms: D000799:Angioedema / Q000175:diagnosis; D003876:Dermatitis, Atopic / Q000175:diagnosis; D003877:Dermatitis, Contact / Q000175:diagnosis; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000188:drug therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D011320:Primary Health Care; D014581:Urticaria / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D005938:Glucocorticoids; D006634:Histamine H1 Antagonists; D007166:Immunosuppressive Agents; D020024:Leukotriene Antagonists
keywords: Allergy; Angioedema; Antihistamines; Hives; Swelling; Urticaria