title: Acute retinal necrosis--a case report.
abstract: Acute retinal necrosis (ARN) is a rare but very severe form of retinitis. In contrast to progressive outer retinal necrosis acute retinal necrosis typically affects immunocompetent individuals. Herpes Simplex and Varicella-zoster viruses play the main role in the development of the disease. We report a case study of a healthy, young male who presented to the ophthalmologist with unilateral visual acuity decrease and eye irritation. The acute retinal necrosis was diagnosed and a therapy was started including both systemic and local anti-viral agents, as well as an oral anticoagulant. Additional systemic steroid therapy was introduced a week later. The regression of retinal inflammatory changes and the improvement of visual acuity were observed. The polymerase chain reaction assay for the presence of viral DNA in serum was negative. The IgM antibody assay for potential causal pathogens was negative, but the level of Varicella-zoster virus IgG antibodies was markedly elevated. During the follow-up, the patient developed retinal detachment and pars plana vitrectomy with silicone oil endotamponade was performed. Although the surgery resulted in the successful retinal reattachment, the final visual acuity remained decreased. Six months after the surgery, the eye was free of the intraocular inflammation and the visual acuity slightly improved.
authors.forename: Ewa
authors.initials: E
authors.lastname: Kuźmicz
authors.forename: Anna
authors.initials: A
authors.lastname: Fizia-Orlicz
authors.forename: Anna
authors.initials: A
authors.lastname: Turno-Kręcicka
authors.forename: Maria
authors.initials: M
authors.lastname: Pomorska
authors.forename: Marta
authors.initials: M
authors.lastname: Misiuk-Hojło
authors.forename: Anna
authors.initials: A
authors.lastname: Mec-Słomska
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage; D000998:Antiviral Agents / Q000008:administration & dosage; D006563:Herpes Zoster Ophthalmicus / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D014645:Herpesvirus 3, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects; D014821:Vitrectomy; D055815:Young Adult
chemical_list: D000925:Anticoagulants; D000998:Antiviral Agents