title: Azithromycin Inhibits Macrophage Tumor Necrosis Factor Secretion in Response to Both Azithromycin-Susceptible and Azithromycin-Resistant Pneumococci.
abstract: We studied the effect of azithromycin (AZM) on macrophage responses to pneumococci. We found that exposure of pneumococci to AZM led to reduced tumor necrosis factor (TNF) secretion by macrophages; this effect was observed in response to both AZM-susceptible and AZM-resistant (AZM-R) pneumococci.
authors.affiliation: Children's Foundation Research Institute at Le Bonheur Children's Hospital; Divisions of Pediatric Critical Care Medicine.
authors.forename: Kim
authors.initials: K
authors.lastname: Ingram
authors.affiliation: Children's Foundation Research Institute at Le Bonheur Children's Hospital; Divisions of.
authors.forename: Matthew
authors.initials: M
authors.lastname: Marker
authors.affiliation: Children's Foundation Research Institute at Le Bonheur Children's Hospital; Divisions of.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Meals
authors.affiliation: Children's Foundation Research Institute at Le Bonheur Children's Hospital; Divisions of Neonatology.
authors.forename: Ajay J
authors.initials: AJ
authors.lastname: Talati
authors.affiliation: Children's Foundation Research Institute at Le Bonheur Children's Hospital; Divisions of Pediatric Critical Care Medicine Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis.
authors.forename: Thomas
authors.initials: T
authors.lastname: Spentzas
authors.affiliation: Children's Foundation Research Institute at Le Bonheur Children's Hospital; Divisions of Pediatric Infectious Diseases, Department of Pediatrics.
authors.forename: B Keith
authors.initials: BK
authors.lastname: English
keywords: TNF; ampicillin; azithromycin; macrophage; pneumococci