title: Asymptomatic Interhypothalamic Adhesions in Children.
abstract: With the use of high-resolution MR imaging techniques, we have increasingly observed anomalies of the hypothalamus characterized by a band of tissue spanning the third ventricle between the hypothalami, often without associated clinical sequelae. Historically, hypothalamic anomalies are highly associated with symptoms referable to a hypothalamic hamartoma, midline congenital disorder, hypothalamic-pituitary dysfunction, or seizures, with very few asymptomatic patients reported. The interhypothalamic tissue described in our cohort was observed incidentally through the routine acquisition of high-resolution T1WI. No referable symptoms were identified in most of the study group. In the appropriate patient population in which associated symptoms are absent, the described hypothalamic anomalies may be incidental and should not be misdiagnosed as hypothalamic hamartomas.
authors.affiliation: From the Department of Radiology (F.N.A.), University of Colorado Anschutz Medical Campus, Aurora, Colorado.
authors.forename: F N
authors.identifier: http://orcid.org/0000-0002-0217-8721
authors.initials: FN
authors.lastname: Ahmed
authors.affiliation: Department of Radiology (N.V.S., D.M.M.), Children's Hospital Colorado, Aurora, Colorado.
authors.forename: N V
authors.identifier: http://orcid.org/0000-0002-2710-7073
authors.initials: NV
authors.lastname: Stence
authors.affiliation: Department of Radiology (N.V.S., D.M.M.), Children's Hospital Colorado, Aurora, Colorado. David.Mirsky@childrenscolorado.org.
authors.forename: D M
authors.identifier: http://orcid.org/0000-0003-2162-515X
authors.initials: DM
authors.lastname: Mirsky
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D002658:Developmental Disabilities / Q000209:etiology; D003937:Diagnosis, Differential; D004700:Endocrine System Diseases / Q000209:etiology; D005260:Female; D006222:Hamartoma / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007027:Hypothalamic Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D007031:Hypothalamus / Q000000981:diagnostic imaging / Q000473:pathology*; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D012640:Seizures / Q000209:etiology; D020542:Third Ventricle / Q000000981:diagnostic imaging / Q000473:pathology; D000267:Tissue Adhesions / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D055815:Young Adult