title: Pre-operative haematological assessment in patients scheduled for major surgery.
abstract: Peri-operative anaemia, blood loss and allogeneic blood transfusion are associated with increased postoperative morbidity and mortality, and prolonged hospital stay. A multidisciplinary, multimodal, individualised strategy, collectively termed 'patient blood management', may reduce or eliminate allogeneic blood transfusion and improve outcomes. This approach has three objectives: the detection and treatment of peri-operative anaemia; the reduction of peri-operative bleeding and coagulopathy; and harnessing and optimising the physiological tolerance of anaemia. This review focuses on the pre-operative evaluation of erythropoiesis, coagulation status and platelet function. Where possible, evidence is graded systematically and recommended therapies follow recently published consensus guidance.
authors.affiliation: Peri-operative Transfusion Medicine, School of Medicine, University of Málaga, Málaga, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Muñoz
authors.affiliation: Department of Internal Medicine, Xanit International Hospital, Benalmádena, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Gómez-Ramírez
authors.affiliation: Department of Anaesthesia and Intensive Care, Evangelical Hospital, Vienna, Austria.
authors.forename: S
authors.initials: S
authors.lastname: Kozek-Langeneker
mesh_terms: D000740:Anemia / Q000175:diagnosis* / Q000628:therapy*; D001778:Blood Coagulation Disorders / Q000175:diagnosis* / Q000628:therapy*; D016063:Blood Loss, Surgical / Q000517:prevention & control; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*; D011300:Preoperative Care / Q000379:methods*