title: Prevention of Weight Regain Following Bariatric Surgery.
abstract: Bariatric surgery is an effective treatment for patients with severe or moderate obesity; however, long-term studies have identified that weight regain occurs post-operatively among a portion of patients. The underlying factors that influence weight regain following bariatric surgery are multifactorial and include endocrine/metabolic alterations, anatomic surgical failure, nutritional indiscretion, mental health issues, and physical inactivity. The extent and significance of these factors is currently uncertain and likely varies between individuals and the operative procedure performed. Multiple observational and non-randomized studies and a few randomized controlled trials have been reported that focus on improving post-operative weight loss. Across all of the behavioral and group support studies, patients in the treatment groups showed either no benefit or modestly greater weight loss than patients in the control groups. There are no randomized controlled trials that have specifically targeted weight regain. Additional clinical research is needed to identify etiological factors and interventional strategies.
authors.affiliation: Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 750 North Lake Shore Drive, Rubloff 9-976, Chicago, IL, 60611, USA. rkushner@northwestern.edu.
authors.forename: Robert F
authors.initials: RF
authors.lastname: Kushner
authors.affiliation: Center for Lifestyle Medicine, Northwestern Medicine, 675 N. St. Clair St. Galter Pavilion, Suite 17-250, Chicago, IL, 60611, USA. kwebb1@nmff.org.
authors.forename: Kirsten Webb
authors.initials: KW
authors.lastname: Sorensen
mesh_terms: D050110:Bariatric Surgery; D000068959:Body Weight Maintenance; D006801:Humans; D009767:Obesity, Morbid / Q000601:surgery*; D011184:Postoperative Period; D012657:Self-Help Groups; D015430:Weight Gain; D015431:Weight Loss
keywords: Bariatric surgery; Prevention; Weight loss; Weight regain