title: Effects of interval aerobic training combined with strength exercise on body composition, glycaemic and lipid profile and aerobic capacity of obese rats.
abstract: The purpose of this study was to investigate the effects of interval aerobic training combined with strength exercise in the same training session on body composition, and glycaemic and lipid profile in obese rats. Sixteen lean Zucker rats and sixteen obese Zucker rats were randomly divided into exercise and sedentary subgroups (4 groups, n = 8). Exercise consisted of interval aerobic training combined with strength exercise in the same training session. The animals trained 60 min/day, 5 days/week for 8 weeks. Body composition, lipid and glycaemic profiles and inflammatory markers were assessed. Results showed that fat mass was reduced in both lean and obese rats following the exercise training (effect size (95% confidence interval (CI)) = 1.8 (0.5-3.0)). Plasma low-density lipoprotein-cholesterol and fasting glucose were lower in the exercise compared to the sedentary groups (d = 2.0 (0.7-3.2) and 1.8 (0.5-3.0), respectively). Plasma insulin was reduced in exercise compared to sedentary groups (d = 2.1 (0.8-3.4)). Some exercise × phenotype interactions showed that the highest decreases in insulin, homeostatic model assessment-insulin resistance, fasting and postprandial glucose were observed in the obese + exercise group (all, P < 0.01). The findings of this study suggest that interval aerobic training combined with strength exercise would improve body composition, and lipid and glycaemic profiles, especially in obese rats.
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.
authors.forename: Irene
authors.initials: I
authors.lastname: Coll-Risco
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.|b Department of Public and Occupational Health , EMGO+ Institute for Health and Care Research, VU University Medical Centre , Amsterdam , The Netherlands.
authors.forename: Virginia A
authors.initials: VA
authors.lastname: Aparicio
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Nebot
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.
authors.forename: Daniel
authors.initials: D
authors.lastname: Camiletti-Moirón
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.
authors.forename: Rosario
authors.initials: R
authors.lastname: Martínez
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.
authors.forename: Garyfallia
authors.initials: G
authors.lastname: Kapravelou
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.
authors.forename: María
authors.initials: M
authors.lastname: López-Jurado
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.
authors.forename: Jesús M
authors.initials: JM
authors.lastname: Porres
authors.affiliation: a Department of Physiology , Faculty of Pharmacy, Faculty of Sport Sciences and Institute of Nutrition & Food Technology, Campus Universitario de Cartuja s/n , Granada , Spain.
authors.forename: Pilar
authors.initials: P
authors.lastname: Aranda
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism*; D001823:Body Composition; D050218:Body Fat Distribution; D001835:Body Weight; D004195:Disease Models, Animal; D004435:Eating; D004734:Energy Metabolism; D000072696:High-Intensity Interval Training / Q000379:methods*; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood*; D008297:Male; D024821:Metabolic Syndrome / Q000628:therapy; D009765:Obesity / Q000097:blood / Q000503:physiopathology*; D010101:Oxygen Consumption; D010805:Physical Conditioning, Animal / Q000379:methods*; D011897:Random Allocation; D011924:Rats, Zucker; D055070:Resistance Training / Q000379:methods*
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D007328:Insulin; D008055:Lipids
keywords: Insulin sensitivity; body composition; cholesterol; metabolic syndrome