title: Supporting systematic reviews using LDA-based document representations.
abstract: BACKGROUND
  Identifying relevant studies for inclusion in a systematic review (i.e. screening) is a complex, laborious and expensive task. Recently, a number of studies has shown that the use of machine learning and text mining methods to automatically identify relevant studies has the potential to drastically decrease the workload involved in the screening phase. The vast majority of these machine learning methods exploit the same underlying principle, i.e. a study is modelled as a bag-of-words (BOW).
  
  
  METHODS
  We explore the use of topic modelling methods to derive a more informative representation of studies. We apply Latent Dirichlet allocation (LDA), an unsupervised topic modelling approach, to automatically identify topics in a collection of studies. We then represent each study as a distribution of LDA topics. Additionally, we enrich topics derived using LDA with multi-word terms identified by using an automatic term recognition (ATR) tool. For evaluation purposes, we carry out automatic identification of relevant studies using support vector machine (SVM)-based classifiers that employ both our novel topic-based representation and the BOW representation.
  
  
  RESULTS
  Our results show that the SVM classifier is able to identify a greater number of relevant studies when using the LDA representation than the BOW representation. These observations hold for two systematic reviews of the clinical domain and three reviews of the social science domain.
  
  
  CONCLUSIONS
  A topic-based feature representation of documents outperforms the BOW representation when applied to the task of automatic citation screening. The proposed term-enriched topics are more informative and less ambiguous to systematic reviewers.
authors.affiliation: School of Computer Science, National Centre for Text Mining, The University of Manchester, Manchester, UK. maxmo2009@gmail.com.
authors.forename: Yuanhan
authors.initials: Y
authors.lastname: Mo
authors.affiliation: School of Computer Science, National Centre for Text Mining, The University of Manchester, Manchester, UK. georgios.kontonatsios@manchester.ac.uk.
authors.forename: Georgios
authors.initials: G
authors.lastname: Kontonatsios
authors.affiliation: School of Computer Science, National Centre for Text Mining, The University of Manchester, Manchester, UK. Sophia.Ananiadou@manchester.ac.uk.
authors.forename: Sophia
authors.initials: S
authors.lastname: Ananiadou
mesh_terms: D035843:Biomedical Research / Q000145:classification*; D057225:Data Mining / Q000379:methods*; D003658:Decision Making, Computer-Assisted; D006801:Humans; D015233:Models, Statistical; D012196:Review Literature as Topic; D060388:Support Vector Machine