title: A new phenylethanoid glycoside from Incarvillea compacta.
abstract: A new phenylethanoid glycoside, 3'''-O-methylcampneoside I (1), was isolated from the 90% ethanolic extract of the roots of Incarvillea compacta, together with three known compounds, campneoside I (2), ilicifolioside A (3), and campneoside II (4). Their structures were determined spectroscopically and compared with previously reported spectral data. Compound 1 existed as epimers and displayed better 1,1-diphenyl-2-picrylhydrazyl (DPPH)-free radical scavenging activity using di-tert-butyl-4-methylphenol (BHT) as the positive control. In addition, pretreatment of human HepG2 cells with compound 1 significantly increased the viability on CCl4-induced cell death.
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development , Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing 100193 , China.
authors.forename: Hai-Feng
authors.initials: HF
authors.lastname: Wu
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development , Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing 100193 , China.
authors.forename: Yin-Di
authors.initials: YD
authors.lastname: Zhu
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development , Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing 100193 , China.
authors.forename: Li-Jing
authors.initials: LJ
authors.lastname: Zhang
authors.affiliation: b Key Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources, Department of Chemistry & Chemical Engineering , Huaihua University , Huaihua 418008 , China.
authors.forename: Qiong-Yu
authors.initials: QY
authors.lastname: Zou
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development , Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing 100193 , China.|b Key Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources, Department of Chemistry & Chemical Engineering , Huaihua University , Huaihua 418008 , China.
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.affiliation: c Jiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection/Jiangsu Key Laboratory for Eco-Agricultural Biotechnology around Hongze Lake , Huaiyin Normal University , Huaian , China.
authors.forename: Ting
authors.initials: T
authors.lastname: Shen
authors.affiliation: c Jiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection/Jiangsu Key Laboratory for Eco-Agricultural Biotechnology around Hongze Lake , Huaiyin Normal University , Huaian , China.
authors.forename: Xin-Feng
authors.initials: XF
authors.lastname: Wang
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development , Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing 100193 , China.
authors.forename: Guo-Xu
authors.initials: GX
authors.lastname: Ma
authors.affiliation: d College of Food Science and Engineering , Yangzhou University , Yangzhou 225001 , China.
authors.forename: Bo-Ran
authors.initials: BR
authors.lastname: Hu
authors.affiliation: c Jiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection/Jiangsu Key Laboratory for Eco-Agricultural Biotechnology around Hongze Lake , Huaiyin Normal University , Huaian , China.
authors.forename: Wei-Cheng
authors.initials: WC
authors.lastname: Hu
authors.affiliation: a Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development , Peking Union Medical College and Chinese Academy of Medical Sciences , Beijing 100193 , China.
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Xu
mesh_terms: D000975:Antioxidants / Q000494:pharmacology; D029402:Bignoniaceae / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000494:pharmacology; D002084:Butylated Hydroxytoluene; D002251:Carbon Tetrachloride / Q000494:pharmacology; D003408:Cresols; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006801:Humans; D015394:Molecular Structure; D010636:Phenols; D010851:Picrates / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D002084:Butylated Hydroxytoluene; D002251:Carbon Tetrachloride; D003408:Cresols; D006027:Glycosides; D010636:Phenols; D010851:Picrates; C000613527:3'''-O-methylcampneoside I; C528844:campneoside II; C032538:4-cresol; C010574:biphenyl; C004931:1,1-diphenyl-2-picrylhydrazyl
keywords: 3′′′-O-methylcampneoside I; Bignoniaceae; Incarvillea compacta; antioxidant activity; hepatoprotective effect; phenylethanoid glycoside