title: A multicentre open trial of labetalol in New Zealand.
abstract: 1 In a multicentre open trial, labetalol was given to 128 patients in ten centres. Forty-three patients had not previously received antihypertensive therapy; the remainder (85 patients) had been on antihypertensive therapy with either unsatisfactory BP control or troublesome side-effects. 2 Thirty-two patients were withdrawn from the trial in the first 6 months of therapy, 24 (19% of the total) because of side-effects. 3 Control of BP was generally satisfactory or considerably improved. Other drugs (usually a diuretic) had to be added in 23 patients. 4 There was an abnormality of liver function in one patient; otherwise there were no biochemical or haematological problems.
authors.forename: G L
authors.initials: GL
authors.lastname: Sanders
authors.forename: D M
authors.initials: DM
authors.lastname: Davies
authors.forename: G M
authors.initials: GM
authors.lastname: Gales
authors.forename: J G
authors.initials: JG
authors.lastname: Rao
authors.forename: M D
authors.initials: MD
authors.lastname: Rawlins
authors.forename: P A
authors.initials: PA
authors.lastname: Routledge