title: Room-Temperature Organocatalytic Cycloaddition of Azides with β-Keto Sulfones: Toward Sulfonyl-1,2,3-triazoles.
abstract: Organocatalytic enamine-azide [3 + 2] cycloadditions between β-keto sulfones and aryl azides can be performed at room temperature in good to excellent yields of products in the presence of catalytic amounts of pyrrolidine (5 mol %). The proposed organocatalytic methodology was found to be applicable to β-keto arylsulfones containing a range of substituents. A wide variety of aryl azides also work. Basically, this constitutes a remarkably efficient protocol for the synthesis of novel 1,2,3-triazole compounds.
authors.affiliation: LASOL - CCQFA, Universidade Federal de Pelotas - UFPel , P.O. Box 354, Pelotas 96010-900, RS, Brazil.
authors.forename: Maiara T
authors.initials: MT
authors.lastname: Saraiva
authors.affiliation: LASOL - CCQFA, Universidade Federal de Pelotas - UFPel , P.O. Box 354, Pelotas 96010-900, RS, Brazil.
authors.forename: Gabriel P
authors.initials: GP
authors.lastname: Costa
authors.affiliation: LASOL - CCQFA, Universidade Federal de Pelotas - UFPel , P.O. Box 354, Pelotas 96010-900, RS, Brazil.
authors.forename: Natália
authors.initials: N
authors.lastname: Seus
authors.affiliation: LASOL - CCQFA, Universidade Federal de Pelotas - UFPel , P.O. Box 354, Pelotas 96010-900, RS, Brazil.
authors.forename: Ricardo F
authors.initials: RF
authors.lastname: Schumacher
authors.affiliation: LASOL - CCQFA, Universidade Federal de Pelotas - UFPel , P.O. Box 354, Pelotas 96010-900, RS, Brazil.
authors.forename: Gelson
authors.initials: G
authors.lastname: Perin
authors.affiliation: Laboratório de Síntese de Produtos Naturais, Universidade Federal de São Carlos , São Carlos 17012-901, SP, Brazil.
authors.forename: Márcio W
authors.initials: MW
authors.lastname: Paixão
authors.affiliation: Departamento de Quimica Organica, Universidad de Cordoba , Campus de Rabanales, Cordoba 5016, Spain.
authors.forename: Rafael
authors.initials: R
authors.lastname: Luque
authors.affiliation: LASOL - CCQFA, Universidade Federal de Pelotas - UFPel , P.O. Box 354, Pelotas 96010-900, RS, Brazil.
authors.forename: Diego
authors.initials: D
authors.lastname: Alves