title: The Changing Epidemiology of Meningococcal Disease.
abstract: The incidence of meningococcal disease is at an historic low in the United States, but prevention remains a priority because of the devastating outcomes and risk for outbreaks. Available vaccines are recommended routinely for persons at increased risk for disease to protect against all major serogroups of Neisseria meningitidis circulating in the United States. Although vaccination has virtually eliminated serogroup A meningococcal outbreaks from the Meningitis Belt of Africa and reduced the incidence of serogroup C disease worldwide, eradication of N meningitidis will unlikely be achieved by currently available vaccines because of the continued carriage and transmission of nonencapsulated organisms.
authors.affiliation: Immunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: anc0@cdc.gov.
authors.forename: Amanda
authors.initials: A
authors.lastname: Cohn
authors.affiliation: Bacterial Diseases Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Jessica
authors.initials: J
authors.lastname: MacNeil
mesh_terms: D000293:Adolescent; D000349:Africa / Q000453:epidemiology; D002648:Child; D004196:Disease Outbreaks; D019353:Endemic Diseases / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D008585:Meningitis, Meningococcal / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D022401:Meningococcal Vaccines / Q000008:administration & dosage / Q000276:immunology; D009345:Neisseria meningitidis / Q000276:immunology; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D018074:Vaccines, Conjugate / Q000276:immunology / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D022401:Meningococcal Vaccines; D018074:Vaccines, Conjugate
keywords: Meningococcal disease; Neisseria meningitidis; Vaccination