title: [Traditional Chinese Medicine Treatment of Gouty Arthritis Based on Syndrome Differentiation].
abstract: OBJECTIVE
  To observe the clinical effect and safety of traditional Chinese medicine (TCM) treatment in gouty arthritis (GA) based on syndrome differentiation.
  
  
  METHODS
  81 patients of GA were enrolled from August 2013 to August 2014. They were divided into syndrome differentiation treatment group (27 cases), disease differentiation treatment group (27 cases) and basic treatment group (27 cases). The patients in syndrome differentiation treatment group were given corresponding TCM drug granules prescription by dialectical syndromes classification. The patients in disease differentiation treatment group were given TCM drug granules prescription. The patients in basic treatment group.were only given Diclofenac Sodium sustained-release tablets in acute phase, and Benzbromarone tablets in chronic phase. After 12 weeks treatments, all the patients received the measurements of serum uric acid (SUA), serum creatinine (SCr), blood urea nitrogen (BUN), triacylglycerol (TG), cholesterol (TC). The clinical efficacy, recurrence rate and adverse reactions were recorded and analyzed.
  
  
  RESULTS
  Syndrome differentiation treatment group achieved higher clinical efficacy than basic treatment group and disease differentiation treatment group (P<0. 05). Moreover, syndrome differentiation treatment were superior to disease differentiation treatment in improving of recurrence rate (P<0. 05). There were no obvious adverse reactions occurred. There were no clinical significant changes in blood, urine routine analysis, and electrocardiogram examination before and 3 months after the treatments.
  
  
  CONCLUSIONS
  The treatment of TCM in patients with GA based on syndrome differentiation showed definite therapeutic effects.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Guo
authors.forename: Huan
authors.initials: H
authors.lastname: Zhao
authors.forename: Yu-xia
authors.initials: YX
authors.lastname: Zhu
authors.forename: Ran-ran
authors.initials: RR
authors.lastname: Zhu
authors.forename: Xing-xing
authors.initials: XX
authors.lastname: Lei
authors.forename: Qiu
authors.initials: Q
authors.lastname: Chen
mesh_terms: D015210:Arthritis, Gouty / Q000145:classification / Q000188:drug therapy*; D001806:Blood Urea Nitrogen; D002784:Cholesterol / Q000097:blood; D003404:Creatinine / Q000097:blood; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008516:Medicine, Chinese Traditional; D008517:Phytotherapy; D012008:Recurrence; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood
chemical_list: D004365:Drugs, Chinese Herbal; D014280:Triglycerides; D014527:Uric Acid; D002784:Cholesterol; D003404:Creatinine