title: A case of bacteremia caused by Dialister pneumosintes and Slackia exigua in a patient with periapical abscess.
abstract: Dialister pneumosintes and Slackia exigua are both obligatory anaerobe and known to be associated with periodontal diseases and other oral infection. We report a case of blood stream infection caused by D. pneumosintes and S. exigua. This occurred in a 78-year-old female patient that presented with general weakness and fever. We revealed that she had a periapical abscess. The blood culture was positive for D. pneumosintes and S. exigua; however, identifying them was challenging. Ultimately, 16S rRNA sequencing was used to identify the organisms. The patient recovered after being treated with ceftriaxone and clindamycin. To the best of our knowledge, this is the first report of bacteremia caused by mixed infection of D. pneumosintes and S. exigua.
authors.affiliation: Department of Laboratory Medicine, Graduate School, Kyung Hee University, Seoul, South Korea.
authors.forename: Min Young
authors.initials: MY
authors.lastname: Lee
authors.affiliation: Department of Laboratory Medicine, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, South Korea.
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Department of Laboratory Medicine, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, South Korea.
authors.forename: Hyun Jung
authors.initials: HJ
authors.lastname: Gu
authors.affiliation: Department of Laboratory Medicine, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, South Korea. Electronic address: leehejo@khmc.or.kr.
authors.forename: Hee Joo
authors.initials: HJ
authors.lastname: Lee
mesh_terms: D039903:Actinobacteria / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D060085:Coinfection; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D008826:Microbial Sensitivity Tests; D010482:Periapical Abscess / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D016896:Treatment Outcome; D045854:Veillonellaceae / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D012336:RNA, Ribosomal, 16S
keywords: 16S rRNA sequencing; Bacteremia; Dialister pneumosintes; Periapical absecess; Slackia exigua