title: Surgical challenges and outcomes of rhegmatogenous retinal detachment in albinism.
abstract: OBJECTIVE
  To report the outcomes and surgical difficulties during rhegmatogenous retinal detachment (RRD) repair in patients with albinism.
  
  
  METHODS
  Retrospective analysis of 10 eyes of 9 patients with albinism that underwent RRD repair was performed. Collected data included demographic details, preoperative examination details, surgical procedure, surgical difficulties, anatomical, and visual outcomes. Outcome measures were retinal reattachment and visual acuity at the last follow-up.
  
  
  RESULTS
  Mean preoperative best-corrected visual acuity (BCVA) was logMAR (Logarithm of the Minimum Angle of Resolution) 2.15 (range 0.9-3.0) with preoperative localization of causative break in six eyes. One eye had proliferative vitreoretinopathy grade C1 preoperatively. Four eyes underwent scleral buckling (SB) and six underwent 20G pars plana vitrectomy (PPV) with silicone oil injection. Intraoperative complication as iatrogenic retinal break occurred in four eyes. For retinopexy during vitrectomy, endolaser delivery was possible in three out of six eyes, whereas three eyes had cryopexy. The mean follow-up was 12 months in SB group (range 1-12; median 12 months) and 5.33 months (range 1-12; median 3 months) in PPV group. Among vitrectomized eye, two eyes had recurrence at 3 months with oil in situ. Rest of the eyes had attached retina at last follow-up. Mean BCVA at last follow-up was logMAR -1.46 (range 0.7-2.0) with mean improvement of -0.57 logMAR.
  
  
  CONCLUSIONS
  Identification of break, induction of posterior vitreous detachment, and endolaser delivery may be difficult during RRD repair in patients with albinism. The incidence of PVR appeared less in these eyes. Both SB and PPV were efficacious and appear to be good surgical techniques for use in this patient population.
authors.affiliation: Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: M K
authors.initials: MK
authors.lastname: Sinha
authors.affiliation: Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: J
authors.identifier: http://orcid.org/0000-0003-1772-3558
authors.initials: J
authors.lastname: Chhablani
authors.affiliation: Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: B S
authors.initials: BS
authors.lastname: Shah
authors.affiliation: Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: R
authors.initials: R
authors.lastname: Narayanan
authors.affiliation: Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
authors.forename: S
authors.initials: S
authors.lastname: Jalali
mesh_terms: D000328:Adult; D016117:Albinism, Ocular / Q000150:complications*; D016115:Albinism, Oculocutaneous / Q000150:complications*; D058450:Endotamponade; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012163:Retinal Detachment / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D012591:Scleral Buckling; D012827:Silicone Oils / Q000008:administration & dosage; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy; D055815:Young Adult
chemical_list: D012827:Silicone Oils