title: Acute reduction in anxiety after deep transcranial magnetic stimulation (DTMS) in unipolar major depression- a systematic review and meta-analysis.
abstract: The current study investigated the anxiolytic properties of the deep transcranial magnetic stimulation (DTMS) in unipolar major depression using a systematic literature review and meta-analysis. Compared to baseline, large anxiolytic and antidepressant outcomes were obtained after 20 daily sessions of high-frequency DTMS according to data from six open-label studies with 95 patients. Unlike the antidepressant effect, the anxiolytic effect was more heterogeneous among studies and did not depend on concurrent treatment with antidepressants.
authors.affiliation: Institute of Psychology and Transfer, University of Bremen, Bremen, Germany. Electronic address: kkedzior@graduate.uwa.edu.au.
authors.forename: Karina Karolina
authors.initials: KK
authors.lastname: Kedzior
authors.affiliation: School of Engineering and Science, Jacobs University Bremen, Bremen, Germany.
authors.forename: Helena Marie
authors.initials: HM
authors.lastname: Gellersen
authors.affiliation: Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
authors.forename: Yiftach
authors.initials: Y
authors.lastname: Roth
authors.affiliation: Department of Life Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
authors.forename: Abraham
authors.initials: A
authors.lastname: Zangen
mesh_terms: D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D001007:Anxiety / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D001008:Anxiety Disorders / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D003865:Major Depressive Disorder / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D050781:Transcranial Magnetic Stimulation; D016896:Treatment Outcome
chemical_list: D014151:Anti-Anxiety Agents; D000928:Antidepressive Agents
keywords: Anxiolytic effect; Deep transcranial magnetic stimulation (DTMS); Depression