title: Combined Undifferentiated and Neuroendocrine Carcinomas of the Gallbladder Appearing as Two Separate Lesions: A Case Report with Radiological-Pathological Correlation.
abstract: We report herein a rare case of incidentally detected combined undifferentiated and neuroendocrine carcinomas of the gallbladder. An incidental gallbladder malignancy was revealed on abdominal ultrasound and multi-detector computed tomography in a 54-year-old man. A short distance from the main polypoid hypoechoic mass at the fundus of the gallbladder, focal wall thickening was noted with prominently increased power Doppler flow. Extended cholecystectomy was performed, and histology confirmed the main polypoid mass as undifferentiated carcinoma and the separate nodule as neuroendocrine carcinoma. To our knowledge, this is the first report presenting two separate lesions of combined gallbladder carcinomas by radiological features.
authors.affiliation: Department of Radiology, School of Medicine, Ewha Womans University, Seoul, South Korea.
authors.forename: So Won
authors.initials: SW
authors.lastname: Lee
authors.affiliation: Department of Radiology, School of Medicine, Ewha Womans University, Seoul, South Korea.
authors.forename: Seung Yon
authors.initials: SY
authors.lastname: Baek
authors.affiliation: Department of Pathology, School of Medicine, Ewha Womans University, Seoul, South Korea.
authors.forename: Sun Hee
authors.initials: SH
authors.lastname: Sung
mesh_terms: D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D018278:Carcinoma, Neuroendocrine / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Gallbladder malignancy; combined gallbladder carcinoma; neuroendocrine carcinoma