title: Severe connective tissue laxity including aortic dilatation in Sotos syndrome.
authors.affiliation: Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Canada.|Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada.
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Hood
authors.affiliation: Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Australia.
authors.forename: George
authors.initials: G
authors.lastname: McGillivray
authors.affiliation: Monash Genetics, Monash Medical Centre, Melbourne, Australia.|Department of Paediatrics, Monash University, Melbourne, Australia.
authors.forename: Matthew F
authors.initials: MF
authors.lastname: Hunter
authors.affiliation: Department of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Roberston
authors.affiliation: Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada.|Department of Pediatrics, University of Ottawa, Ottawa, Canada.
authors.forename: Dennis E
authors.initials: DE
authors.lastname: Bulman
authors.affiliation: Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada.|Department of Pediatrics, University of Ottawa, Ottawa, Canada.|Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Canada.
authors.forename: Kym M
authors.initials: KM
authors.lastname: Boycott
authors.affiliation: Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Australia.
authors.forename: Zornitza
authors.initials: Z
authors.lastname: Stark
authors.affiliation: Care4Rare Canada Consortium, Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Canada.
mesh_terms: D000328:Adult; D001018:Aortic Diseases / Q000209:etiology* / Q000473:pathology; D003240:Connective Tissue Diseases / Q000209:etiology* / Q000473:pathology; D005260:Female; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase; D006801:Humans; D007223:Infant; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics*; D008297:Male; D009154:Mutation / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D010375:Pedigree; D058495:Sotos Syndrome / Q000150:complications* / Q000235:genetics
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D009687:Nuclear Proteins; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase; C113272:NSD1 protein, human