title: Toward Network Biology in E. coli Cell.
abstract: E. coli has been a critically important model research organism for more than 50 years, particularly in molecular biology. In 1997, the E. coli draft genome sequence was published. Post-genomic techniques and resources were then developed that allowed E. coli to become a model organism for systems biology. Progress made since publication of the E. coli genome sequence will be summarized.
authors.affiliation: Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. hmori@gtc.naist.jp.
authors.forename: Hirotada
authors.initials: H
authors.lastname: Mori
authors.affiliation: Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. takeriki0502@gmail.com.
authors.forename: Rikiya
authors.initials: R
authors.lastname: Takeuchi
authors.affiliation: Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. y-otsuka@bs.naist.jp.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Otsuka
authors.affiliation: Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. sbowden@umn.edu.
authors.forename: Steven
authors.initials: S
authors.lastname: Bowden
authors.affiliation: Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. k.yokoyama@hamayaku.ac.jp.
authors.forename: Katsushi
authors.initials: K
authors.lastname: Yokoyama
authors.affiliation: Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. muto@bs.naist.jp.
authors.forename: Ai
authors.initials: A
authors.lastname: Muto
authors.affiliation: The Biotechnology Institute, University of Minnesota, 1479 Gortner Avenue, St. Paul, MN, 55108-6106, USA. libourel@umn.eud.
authors.forename: Igor
authors.initials: I
authors.lastname: Libourel
authors.affiliation: Department of Biological Sciences, Purdue University, West Lafayette, IN, 47907, USA. blwanner@genetics.med.harvard.edu.
authors.forename: Barry L
authors.initials: BL
authors.lastname: Wanner
mesh_terms: D019295:Computational Biology; D004926:Escherichia coli / Q000235:genetics*; D015723:Gene Library; D057166:High-Throughput Screening Assays
keywords: E. coli; Network biology; Plasmid clone libraries