title: Innovative Therapeutic Strategies in the Treatment of Meningioma.
abstract: Few medical options are available for progressive/recurrent and atypical/anaplastic meningiomas. New developments in chemotherapeutic options for meningiomas have been explored over the past decade. We review the more recent literature to recognize studies investigating recent medical and chemotherapeutic agents that have been experienced or are currently being tested for meningiomas. Combination therapies affecting multiple molecular targets are currently opening up and present significant promise as adjuvant therapeutic options. However, there is an evident need for new molecular studies in order to better understand the biology of meningiomas and, thus, to identify new and more specific therapeutic targets.
authors.affiliation: Neurosurgical Clinic, Department of Neuroscience, University of Messina, Messina, Italy gcaruso@unime.it.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Caruso
authors.affiliation: Department of Neurological Surgery, Saint Louis University School of Medicine, Saint Louis, MO, U.S.A.
authors.forename: Samer K
authors.initials: SK
authors.lastname: Elbabaa
authors.affiliation: Department of Neurosurgery, University Hospital Alicante, Miguel Hernandez University School of Medicine, Alicante, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Gonzalez-Lopez
authors.affiliation: Department of Human Pathology, University of Messina, Messina, Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Barresi
authors.affiliation: Neurosurgical Clinic, Department of Neuroscience, University of Messina, Messina, Italy.
authors.forename: Marcello
authors.initials: M
authors.lastname: Passalacqua
authors.affiliation: Neurosurgical Clinic, Department of Neuroscience, University of Messina, Messina, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Caffo
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008579:Meningioma / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents
keywords: Meningioma; nanomedicine; review; surgery; targeted therapies; treatment