title: Partial laryngectomy in glottic cancer: complications and oncological results.
abstract: BACKGROUND
  Most patients with laryngeal carcinoma present tumors in the glottis that can be treated by different treatment modalities. Some authors consider open partial laryngectomy as obsolete, while others still deem this as a viable and cost-efficient option.
  
  
  OBJECTIVE
  To compare the oncological and functional results of a series of patients undergoing partial laryngectomy vs. external radiotherapy for the treatment of glottic cancer.
  
  
  METHODS
  Historical cohort study with a series of glottic carcinoma patients undergoing partial laryngectomy or external radiotherapy during a period of ten years.
  
  
  RESULTS
  Sixty-two patients with glottic carcinoma were included. Group A comprised those submitted to partial laryngectomy (n=30), and Group B, those who underwent radiotherapy (n=32). They were homogeneous in the comparison of mean age, 56.4 vs. 60.4 years (p=0.12) and distribution in pathological stage (p=0.91). With regard to oncological outcome, there were no differences in distant metastasis rates, or second primary tumor between groups (p=1.0), as well as in disease-free time, laryngeal rescue-free time, and overall five-year survival. Severe complication rates were also similar between groups.
  
  
  CONCLUSIONS
  Open partial laryngectomy had complication rates and oncological results similar to those of radiotherapy for patients with glottic carcinomas and should still be considered among the main available therapeutic options.
authors.affiliation: Department of Surgery, Division of Otolaryngology and Head and Neck Surgery, Hospital São José, Joinville, SC, Brazil. Electronic address: entbrazil@gmail.com.
authors.forename: Agnaldo José
authors.initials: AJ
authors.lastname: Graciano
authors.affiliation: Department of Surgery, Hospital São José, Joinville, SC, Brazil.
authors.forename: Marina
authors.initials: M
authors.lastname: Sonagli
authors.affiliation: Department of Surgery, Hospital São José, Joinville, SC, Brazil.
authors.forename: Ana Gabriela Clemente
authors.initials: AG
authors.lastname: da Silva
authors.affiliation: Department of Surgery, Division of Otolaryngology and Head and Neck Surgery, Hospital São José, Joinville, SC, Brazil.
authors.forename: Carlos Augusto
authors.initials: CA
authors.lastname: Fischer
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil.
authors.forename: Carlos Takahiro
authors.initials: CT
authors.lastname: Chone
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D007825:Laryngectomy / Q000009:adverse effects / Q000379:methods; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications; D012008:Recurrence; D015996:Survival Rate
keywords: Carcinoma; Laringe; Laringectomia; Laryngectomy; Larynx; Radioterapia; Radiotherapy