title: Lymphadenectomy During Pulmonary Metastasectomy.
abstract: Pulmonary metastasectomy continues to be an effective approach to prolong survival in appropriately selected patients. The incidence of lymphatic spread is more common than previously recognized, with an estimate of 20% to 25% across multiple tumor types. The presence of metastatically involved lymph nodes adversely affects survival. What remains unclear is whether N1 vs N2, or the number of stations involved affects survival differently. The role of surgery for pulmonary metastasectomy in the patient with nodal metastases will likely expand with ongoing improvements in targeted and immunotherapies.
authors.affiliation: Division of Thoracic & Cardiovascular Surgery, Department of Surgery, University of Oklahoma Health Sciences Center, 920 Stanton L. Young Boulevard, WP 2230, Oklahoma City, OK 73104, USA.
authors.forename: James Matthew
authors.initials: JM
authors.lastname: Reinersman
authors.affiliation: Division of General Thoracic Surgery, Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address: wigle.dennis@mayo.edu.
authors.forename: Dennis A
authors.initials: DA
authors.lastname: Wigle
mesh_terms: D006801:Humans; D007432:Intraoperative Period; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery*; D008197:Lymph Node Excision / Q000379:methods*; D008207:Lymphatic Metastasis; D059146:Metastasectomy / Q000379:methods*
keywords: Lung metastasis; Lymphadenectomy; Metastasectomy