title: Distribution and chemical coding patterns of cocaine- and amphetamine-regulated transcript-like immunoreactive (CART-LI) neurons in the enteric nervous system of the porcine stomach cardia.
abstract: The aim of this study was to determine the presence of cocaine- and amphetamine-regulated transcript-like immunoreactive (CART-LI) neurons and co-localisation of CART with vesicular acetylcholine transporter (VAChT), neuronal nitric oxide synthase (n-NOS), vasoactive intestinal polypeptide (VIP), substance P (SP) and leu-enkephalin (LENK) in the enteric nervous system of the porcine gastric cardia by using a double-labelling immunofluorescence technique. CART-LI neurons were observed in the myenteric plexus (18.2±2.6%). A dense network of CART-LI nerve fibers was mainly observed in the muscular layer. CART showed co-localization mainly with VAChT, n-NOS, VIP and to a lesser degree with LENK and SP. Distribution of CART and its co-localization with other neurotransmitters suggest that this peptide plays an important role in gastric motility in the pig.
authors.forename: W
authors.initials: W
authors.lastname: Rękawek
authors.forename: P
authors.initials: P
authors.lastname: Sobiech
authors.forename: S
authors.initials: S
authors.lastname: Gonkowski
authors.forename: K
authors.initials: K
authors.lastname: Żarczyńska
authors.forename: A
authors.initials: A
authors.lastname: Snarska
authors.forename: T
authors.initials: T
authors.lastname: Waśniewski
authors.forename: J
authors.initials: J
authors.lastname: Wojtkiewicz
mesh_terms: D000818:Animals; D002299:Cardia / Q000294:innervation*; D005786:Gene Expression Regulation / Q000502:physiology; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism*; D009474:Neurons / Q000145:classification / Q000378:metabolism*; D013552:Swine / Q000502:physiology*
chemical_list: D009419:Nerve Tissue Proteins