title: [Hypertension and diabetes mellitus].
abstract: The goal of diabetes treatment is to maintain a quality of life. Hypertension is a common diabetes comorbidity and is a risk factor for mortality. Epidemiological studies show that blood pressure (BP) lowering is associated with improving prognosis in this population. However, recent clinical trials and meta-analyses report no benefit of an intensive BP lowering of < 130/80 mmHg on mortality and cardiovascular complications, except stroke. Furthermore, the excess BP lowering should be avoided not to increase the risk of adverse effects such as hypotension, especially in elderly patients or those with adverse vascular complications. In Japanese diabetes guidelines, a BP target of < 130/80 mmHg is still recommended in diabetic patients with hypertension because of the high incidence of stroke in Japanese.
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Araki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Maegawa
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D048909:Diabetes Complications; D003920:Diabetes Mellitus; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D017410:Practice Guidelines as Topic; D011788:Quality of Life
chemical_list: D000959:Antihypertensive Agents