title: Reduced graphene oxide-Hemin-Au nanohybrids: Facile one-pot synthesis and enhanced electrocatalytic activity towards the reduction of hydrogen peroxide.
abstract: A facile and effective strategy is demonstrated for the synthesis of ternary reduced graphene oxide-Hemin-Au (rGO-H-Au) nanohybrids. The nanohybrids were synthesized through a one-pot in situ reduction of GO and HAuCl4 under alkaline conditions using GO, Hemin and HAuCl4 as the starting materials. The synthesis process can be finished within 1h in a solution phase, without adding any additional surfactant, stabilizing agent and toxic or harsh chemical reducing agents. The resulting nanohybrids were characterized by UV-vis spectroscopy, Raman spectroscopy, transmission electron microscopy (TEM), and so on. Electrochemical measurements showed that the rGO-H-Au nanohybrids exhibited good electrocatalytic activity for the reduction of hydrogen peroxide (H2O2). Based on this property, a simple and highly sensitive amperometric biosensor for H2O2 had been developed. The linear relationships were obtained from 0.1 µM to 40 µM and the detection limit was estimated to be 30 nM. The simple and sensitive sensing platform showed great promising applications in the pharmaceutical, clinical and industrial detection of H2O2.
authors.affiliation: School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China.
authors.forename: Chang-Jie
authors.initials: CJ
authors.lastname: Gu
authors.affiliation: School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China. Electronic address: kongfy@ycit.edu.cn.
authors.forename: Fen-Ying
authors.initials: FY
authors.lastname: Kong
authors.affiliation: School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China.
authors.forename: Zhi-Dong
authors.initials: ZD
authors.lastname: Chen
authors.affiliation: School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China.
authors.forename: Da-He
authors.initials: DH
authors.lastname: Fan
authors.affiliation: School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China.
authors.forename: Hai-Lin
authors.initials: HL
authors.lastname: Fang
authors.affiliation: School of Chemistry and Chemical Engineering, Yancheng Institute of Technology, Yancheng 224051, China. Electronic address: kongfy@ycit.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D055664:Electrochemical Techniques / Q000379:methods*; D006046:Gold / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D006427:Hemin / Q000737:chemistry; D006801:Humans; D006861:Hydrogen Peroxide / Q000302:isolation & purification*; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission
chemical_list: D006427:Hemin; D006046:Gold; D006108:Graphite; D006861:Hydrogen Peroxide
keywords: Au nanoparticles; Electrocatalysis; Graphene; Hemin; Hydrogen peroxide