title: Short-term outcomes of local infiltration anaesthetic in total knee arthroplasty: a randomized controlled double-blinded controlled trial.
abstract: BACKGROUND
  The primary objective of the study was to determine if local infiltration anaesthetic (LIA) reduced total length of hospital stay in total knee arthroplasty (TKA) patients. The study also examined whether LIA improves early pain management, patient satisfaction and range of motion in TKA patients.
  
  
  METHODS
  We conducted a randomized controlled double-blinded study. Fifty patients undergoing TKA were randomized to receive either placebo or LIA at the time of surgery and on the first day post-operatively. Pain scores, level of satisfaction and range of motion were recorded preoperatively and post-operatively.
  
  
  RESULTS
  There was no statistical difference between the groups for length of stay, post-operative pain scores, satisfaction scores or range of motion 6 weeks post-operatively.
  
  
  CONCLUSIONS
  This randomized double-blinded trial did not demonstrate a decrease in pain or reduction of length of stay due to local infiltration analgesia.
authors.affiliation: Department of Orthopaedics, Prince of Wales Hospital, Sydney, New South Wales, Australia.|Department of Orthopaedics, Launceston General Hospital, Launceston, Tasmania, Australia.
authors.forename: Jonathan S
authors.initials: JS
authors.lastname: Mulford
authors.affiliation: Department of Orthopaedics, Prince of Wales Hospital, Sydney, New South Wales, Australia.
authors.forename: Anna
authors.initials: A
authors.lastname: Watson
authors.affiliation: Department of Orthopaedics, Prince of Wales Hospital, Sydney, New South Wales, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Broe
authors.affiliation: Department of Orthopaedics, Prince of Wales Hospital, Sydney, New South Wales, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Solomon
authors.affiliation: Department of Orthopaedics, Prince of Wales Hospital, Sydney, New South Wales, Australia.
authors.forename: Andreas
authors.initials: A
authors.lastname: Loefler
authors.affiliation: South Western Sydney Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
authors.forename: Ian
authors.initials: I
authors.lastname: Harris
mesh_terms: D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects / Q000379:methods*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D059408:Pain Management / Q000379:methods; D010147:Pain Measurement / Q000379:methods; D010149:Postoperative Pain / Q000188:drug therapy*; D017060:Patient Satisfaction; D016059:Range of Motion, Articular / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local
keywords: anaesthetic; arthroplasty; knee replacement; length of stay; local