title: Analysis of high risk factors and characteristics of coronary artery in premenopausal women with coronary artery disease.
abstract: OBJECTIVE
  The aim of this study was to explore the high risk factors and coronary lesion features in premenopausal women with coronary artery disease (CAD) and provide guideline for diagnosis and therapy.
  
  
  METHODS
  114 premenopausal women and 134 postmenopausal women were conducted coronary angiography in our hospital from September, 2012 to September, 2014. According to the results of coronary angiography, premenopausal and postmenopausal women with coronary artery disease were divided into two groups respectively, including 48 premenopausal women with CAD group, 66 premenopausal women with normal coronary artery group, 76 postmenopausal women with CAD group and 58 postmenopausal women with normal coronary artery group. Clinical characteristics and coronary lesion features were analyzed.
  
  
  RESULTS
  Incidence rates of hypertension disease and diabetes were higher in premenopausal women with CAD group than control group. Most of premenopausal women suffered from single vessel lesion and the length of impaired vessel was less than 20 mm, meanwhile, postmenopausal women easily confronted from double vessels or mutivessle lesion and the length of impaired vessel was more than 20 mm. Left anterior descending coronary artery lesion was common for premenopausal women.
  
  
  CONCLUSIONS
  Hypertension disease and diabetes were the main high risk factors for premenopausal women and high triglyceride was the optimal predictable factor, furthermore, single vessel lesion and short artery lesion were common in premenopausal women, which often happened in the anterior descending coronary artery.
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Zhijuan
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Jianxin
authors.initials: J
authors.lastname: Cheng
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Yan
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Xiangyong
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan University of Science and Technology Luoyang 471003, China.
authors.forename: Debao
authors.initials: D
authors.lastname: Zhao
keywords: CAD; coronary angiography; coronary artery feature; premenopause; risk factor