title: Sialadenitis following low dose I-131 diagnostic thyroid scan with Thyrogen® (recombinant human thyroid stimulating hormone--thyrotropin alfa).
abstract: Salivary dysfunction and sialadenitis are well known complications of radioiodine treatment for thyroid cancer. The parotid gland is more frequently affected and the salivary gland injury is dose related. The symptoms may develop shortly after therapeutic Iodine 131(I-131) administration or months later and progress with time. The development of unilateral parotiditis following a low dose, diagnostic I-131 scan performed following Thyrogen stimulation in a patient without prior history of sialadenitis is rare in our experience, and has not been reported in the medical literature.
authors.affiliation: Department of Radiology and Medical Imaging University of Virginia, USA.
authors.forename: Marta E
authors.initials: ME
authors.lastname: Gonzalez
authors.affiliation: Department of Radiology and Medical Imaging University of Virginia, USA.
authors.forename: Thomas Jose Eluvathingal
authors.initials: TJ
authors.lastname: Muttikkal
authors.affiliation: Department of Radiology and Medical Imaging University of Virginia, USA.
authors.forename: Patrice K
authors.initials: PK
authors.lastname: Rehm
mesh_terms: D000368:Aged; D002291:Carcinoma, Papillary / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000009:adverse effects*; D011829:Radiation Dosage; D011877:Radionuclide Imaging; D012793:Sialadenitis / Q000209:etiology*; D013961:Thyroid Gland / Q000000981:diagnostic imaging*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D057073:Thyrotropin Alfa / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D007457:Iodine Radioisotopes; D057073:Thyrotropin Alfa
keywords: Iodine-131; Thyrogen; diagnostic; salivary glands; sialadenitis