title: Corticosteroids in Lupus.
abstract: Corticosteroids are the mainstay of treatment of systemic lupus erythematosus, with most patients receiving them at some point in the course of their disease. Corticosteroid use is associated with significant side effects, including infections, hypertension, hyperglycemia, osteoporosis, avascular necrosis, myopathy, cataracts, and glaucoma. Dosing regimens are based on limited data, with the goal of adequately controlling inflammatory symptoms while minimizing steroid exposure in order to reduce adverse effects.
authors.affiliation: Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA. Electronic address: kasturis@hss.edu.
authors.forename: Shanthini
authors.initials: S
authors.lastname: Kasturi
authors.affiliation: Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
authors.forename: Lisa R
authors.initials: LR
authors.lastname: Sammaritano
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000453:epidemiology / Q000628:therapy; D002386:Cataract / Q000139:chemically induced; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000139:chemically induced / Q000453:epidemiology / Q000628:therapy; D005901:Glaucoma / Q000139:chemically induced; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007239:Infections / Q000139:chemically induced; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy* / Q000453:epidemiology; D009135:Muscular Diseases / Q000139:chemically induced; D010020:Osteonecrosis / Q000139:chemically induced; D010024:Osteoporosis / Q000139:chemically induced / Q000453:epidemiology / Q000628:therapy; D010437:Peptic Ulcer / Q000139:chemically induced / Q000453:epidemiology / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D005938:Glucocorticoids
keywords: Corticosteroids; Glucocorticoids; Methylprednisolone; Prednisone; Systemic lupus erythematosus