title: Chemical constituents of the mangrove-associated fungus Capnodium sp. SZ-F22. A new eremophilane sesquiterpene.
abstract: A new eremophilane sesquiterpene, capnodiumone (1), along with five known eremophilane sesquiterpenes (2-6) and eight other compounds (7-14), have been isolated from a mangrove-associated fungus Capnodium sp. SZ-F22. The chemical structures were elucidated on the basis of extensive spectroscopic analysis. The broth extract of the fungus exhibited a good inhibitory effect on the mycelium growth against Fusarium graminearum at 100 μg/mL, however, all the 14 compounds showed no expected antifungal activity. The probable reasons were discussed.
authors.affiliation: a Institute of Marine Biology & Natural Products, Ocean College , Zhejiang University , Hangzhou , China.
authors.forename: Haibing
authors.initials: H
authors.lastname: He
authors.affiliation: a Institute of Marine Biology & Natural Products, Ocean College , Zhejiang University , Hangzhou , China.
authors.forename: Zhongjun
authors.initials: Z
authors.lastname: Ma
authors.affiliation: a Institute of Marine Biology & Natural Products, Ocean College , Zhejiang University , Hangzhou , China.
authors.forename: Qianqian
authors.initials: Q
authors.lastname: Wang
authors.affiliation: b State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences , Zhejiang University , Hangzhou , China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.affiliation: c Neilingding-Futian National Nature Reserve Administration Bureau of Guangdong , Shenzhen , China.
authors.forename: Hualin
authors.initials: H
authors.lastname: Xu
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D005670:Fusarium / Q000187:drug effects; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D053833:Wetlands
chemical_list: D000935:Antifungal Agents; D012717:Sesquiterpenes
keywords: Capnodium sp.; Mangrove-associated fungus; chemical constituents; eremophilane sesquiterpenes;  Fusarium graminearum