title: Optimizing Management of Patients with Adult T Cell Leukemia-Lymphoma.
abstract: Adult T cell leukemia-lymphoma is a rare disease with a high mortality rate, and is challenging for the clinician. Early allogeneic stem cell transplant can confer durable remission. As novel therapeutic agents become available to treat T cell malignancies, it is increasingly important that medical oncologists, hematologists, and hematopathologists recognize and accurately diagnose adult T cell leukemia-lymphoma. There is no uniform standard of treatment of adult T cell leukemia-lymphoma, and clinical trials remain critical to improving outcomes. Here we present one management approach based on the recent advances in treatment for adult T cell leukemia-lymphoma patients.
authors.affiliation: Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD 21204, USA. jyared@umm.edu.
authors.forename: Jean A
authors.initials: JA
authors.lastname: Yared
authors.affiliation: Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD 21204, USA. amykimballmd@gmail.com.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Kimball
keywords: ATL; ATLL; HTLV-1; adult T cell leukemia-lymphoma; allogeneic; antiviral treatment; chemotherapy; transplantation