title: The role of siderophores in metal homeostasis of members of the genus Burkholderia.
abstract: Although members of the genus Burkholderia can utilize a high-affinity iron uptake system to sustain growth under iron-limiting conditions, many strains also produce siderophores, suggesting that they may serve alternative functions. Here we demonstrate that the two Burkholderia siderophores pyochelin and ornibactin can protect the cells from metal toxicity and thus play an alternative role in metal homeostasis. We also demonstrate that metals such as copper and zinc induce the production of ornibactin.
authors.affiliation: Department of Microbiology, Institute of Plant Biology, University of Zurich, Zurich, Switzerland.
authors.forename: Anugraha
authors.initials: A
authors.lastname: Mathew
authors.affiliation: Department of Microbiology, Institute of Plant Biology, University of Zurich, Zurich, Switzerland.
authors.forename: Christian
authors.initials: C
authors.lastname: Jenul
authors.affiliation: Department of Microbiology, Institute of Plant Biology, University of Zurich, Zurich, Switzerland.
authors.forename: Aurelien L
authors.initials: AL
authors.lastname: Carlier
authors.affiliation: Department of Microbiology, Institute of Plant Biology, University of Zurich, Zurich, Switzerland.
authors.forename: Leo
authors.initials: L
authors.lastname: Eberl
mesh_terms: D019117:Burkholderia / Q000187:drug effects* / Q000378:metabolism*; D006706:Homeostasis; D008670:Metals / Q000378:metabolism* / Q000633:toxicity*; D010636:Phenols / Q000378:metabolism; D017262:Siderophores / Q000378:metabolism*; D013844:Thiazoles / Q000378:metabolism
chemical_list: D008670:Metals; D010636:Phenols; D017262:Siderophores; D013844:Thiazoles; C025316:pyochelin