title: Laser Ablation in Pediatric Epilepsy.
abstract: Laser ablation is an emerging, minimally invasive treatment for selected children with intractable focal epilepsy with improved procedural morbidity. Data for children lag similar studies in adults, but the hope is for near-equivalent seizure-control rates and improved neuropsychological outcome when compared with standard open surgical resection. The approach seems particularly beneficial when dealing with deep, focal lesions, such as hypothalamic hamartomas or hippocampal sclerosis.
authors.affiliation: Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, 4800 Sand Point Way NE, Seattle, WA 98145-5005, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Buckley
authors.affiliation: Division of Neurosurgery, Seattle Children's Hospital, University of Puerto Rico, San Juan, PR, USA.
authors.forename: Samuel
authors.initials: S
authors.lastname: Estronza-Ojeda
authors.affiliation: Department of Neurological Surgery, Seattle Children's Hospital, University of Washington, 4800 Sand Point Way NE, Seattle, WA 98145-5005, USA. Electronic address: jojemann@u.washington.edu.
authors.forename: Jeffrey G
authors.initials: JG
authors.lastname: Ojemann
mesh_terms: D001921:Brain / Q000601:surgery*; D002648:Child; D004827:Epilepsy / Q000601:surgery*; D006222:Hamartoma / Q000601:surgery; D006801:Humans; D007027:Hypothalamic Diseases / Q000601:surgery; D053685:Laser Therapy / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods*; D012640:Seizures / Q000601:surgery*; D016896:Treatment Outcome
keywords: Hypothalamic hamartoma; Laser ablation; Mesial temporal sclerosis; Neuropsychological outcome; Pediatric epilepsy surgery