title: Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report.
abstract: Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydrochloride in a pharmaceutical factory, exhibited severe inhalation injury and respiratory symptoms. Laboratory tests revealed reduced white blood cell counts and lowered platelet levels during the first 6 days after the skin exposure to nitrogen mustard. Following treatment with mechanical ventilation, immunity-enhancing agents and nutritional supplements for 1 month, the patient successfully recovered and was released from hospital.
authors.affiliation: Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Zhidan
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Song
authors.initials: S
authors.lastname: Chen
authors.affiliation: Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Dongmei
authors.initials: D
authors.lastname: Zhao
authors.affiliation: Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Fangxiao
authors.initials: F
authors.lastname: Zhang
authors.affiliation: Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Ziwei
authors.initials: Z
authors.lastname: Hu
authors.affiliation: Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Feng
authors.initials: F
authors.lastname: Xiao
authors.affiliation: Intensive Care Unit, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
authors.forename: Xiaochun
authors.initials: X
authors.lastname: Ma
keywords: myelosuppression; nitrogen mustard hydrochloride; respiratory failure