title: Multiparametric MR Imaging of Breast Cancer.
abstract: Breast MR imaging has increased in popularity over the past 2 decades due to evidence of its high sensitivity for cancer detection. Current clinical MR imaging approaches rely on the use of a dynamic contrast-enhanced acquisition that facilitates morphologic and semiquantitative kinetic assessments of breast lesions. The use of more functional and quantitative parameters holds promise to broaden the utility of MR imaging and improve its specificity. Because of wide variations in approaches for measuring these parameters and the considerable technical challenges, robust multicenter data supporting their routine use are not yet available, limiting current applications of many of these tools to research purposes.
authors.affiliation: Breast Imaging Section, Department of Radiology, Seattle Cancer Care Alliance, University of Washington, 825 Eastlake Avenue East, PO Box 19023, Seattle, WA 98109-1023, USA.
authors.forename: Habib
authors.initials: H
authors.lastname: Rahbar
authors.affiliation: Breast Imaging Section, Department of Radiology, Seattle Cancer Care Alliance, University of Washington, 825 Eastlake Avenue East, PO Box 19023, Seattle, WA 98109-1023, USA. Electronic address: scp3@uw.edu.
authors.forename: Savannah C
authors.initials: SC
authors.lastname: Partridge
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D001943:Breast Neoplasms / Q000175:diagnosis*; D003287:Contrast Media / Q000493:pharmacokinetics*; D038524:Diffusion Magnetic Resonance Imaging / Q000639:trends*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000639:trends*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D057054:Molecular Imaging / Q000639:trends; D064847:Multimodal Imaging / Q000639:trends*
chemical_list: D014408:Biomarkers, Tumor; D003287:Contrast Media
keywords: Breast cancer; Diffusion-weighted imaging; Dynamic contrast enhanced; Magnetic resonance spectroscopy; Multiparametric breast MR imaging