title: Letting Go of JuNK by Disassembly of Adhesive Complexes.
abstract: Immature neural circuits form excessive synaptic connections that are later refined through pruning of exuberant branches. In this issue, Bornstein et al. identify a role for JNK signaling in selective axon elimination through disassembly of cell adhesion complexes.
authors.affiliation: Department of Neurobiology/HHMI, University of Massachusetts Medical School, Worcester, MA 01605, USA.
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Farley
authors.affiliation: Department of Neurobiology/HHMI, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: marc.freeman@umassmed.edu.
authors.forename: Marc R
authors.initials: MR
authors.lastname: Freeman
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000235:genetics*; D020935:MAP Kinase Signaling System / Q000235:genetics*; D024521:Mushroom Bodies / Q000166:cytology* / Q000254:growth & development*; D009473:Neuronal Plasticity / Q000235:genetics*; D036123:Receptor, EphA5 / Q000235:genetics*
chemical_list: D036123:Receptor, EphA5