title: Association Between Family History and Hypertension Among Chinese Elderly.
abstract: This study aimed to evaluate the association between family history and prevalence of hypertension among Chinese community elderly, and also explore the gender difference. A population-based cross-sectional study was conducted in Miyun district of Beijing, in 2014. The family history information was obtained from each subject and was divided into 3 categories, no family history (FH0), 1 generation of first-degree relatives with hypertension (FH1), and 2 generations of first-degree relatives with hypertension (FH2). The prevalence of hypertension was 53.0%. Participants with positive family history had a significantly higher prevalence of hypertension (67.5%, 95% CI: 63.3-71.7) than those without (47.9%, 95% CI: 45.2-50.6), and even among participants without hypertension, the blood pressure levels were higher with positive FH. Multiple logistic regression analysis showed that a significantly linear-trend increase in hypertension according to family history of first degree relative numbers was observed in both genders (P for trend < 0.001). This study suggests that family history had not only a significant but also graded association with hypertension and with blood pressure levels, and this association exists even among those without hypertension.
authors.affiliation: From the Institute of Geriatrics, Chinese PLA General Hospital, Beijing Key Laboratory of Aging and Geriatrics (ML, YH, JW, LW, YW, DZ, JZ, YY), State Key Laboratory of Kidney Disease (YH), and Department of Chinese Traditional Medicine and Acupuncture (BJ), Chinese PLA General Hospital, Beijing, China.
authors.forename: Miao
authors.initials: M
authors.lastname: Liu
authors.forename: Yao
authors.initials: Y
authors.lastname: He
authors.forename: Bin
authors.initials: B
authors.lastname: Jiang
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
authors.forename: Lei
authors.initials: L
authors.lastname: Wu
authors.forename: Yiyan
authors.initials: Y
authors.lastname: Wang
authors.forename: Di
authors.initials: D
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Zeng
authors.forename: Yao
authors.initials: Y
authors.lastname: Yao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005190:Family; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors