title: Temporal epilepsy seizures monitoring and prediction using cross-correlation and chaos theory.
abstract: Temporal seizures due to hippocampal origins are very common among epileptic patients. Presented is a novel seizure prediction approach employing correlation and chaos theories. The early identification of seizure signature allows for various preventive measures to be undertaken. Electro-encephalography signals are spectrally broken down into the following sub-bands: delta; theta; alpha; beta; and gamma. The proposed approach consists of observing a high correlation level between any pair of electrodes for the lower frequencies and a decrease in the Lyapunov index (chaos or entropy) for the higher frequencies. Power spectral density and statistical analysis tools were used to determine threshold levels for the lower frequencies. After studying all five sub-bands, the analysis has revealed that the seizure signature can be extracted from the delta band and the high frequencies. High frequencies are defined as both the gamma band and the ripples occurring within the 60-120 Hz sub-band. To validate the proposed approach, six patients from both sexes and various age groups with temporal epilepsies originating from the hippocampal area were studied using the Freiburg database. An average seizure prediction of 30 min, an anticipation accuracy of 72%, and a false-positive rate of 0% were accomplished throughout 200 h of recording time.
authors.affiliation: Département d'informatique et d'ingénierie , Université du Québec en Outaouais , 101 Saint-Jean-Bosco , Gatineau , PQ , J8Y 3G5 , Canada.
authors.forename: Tahar
authors.initials: T
authors.lastname: Haddad
authors.affiliation: Ciena Canada , 3500 Carling Avenue , Ottawa , ON , K2H 8E7 , Canada.
authors.forename: Naim
authors.initials: N
authors.lastname: Ben-Hamida
authors.affiliation: Département d'informatique et d'ingénierie , Université du Québec en Outaouais , 101 Saint-Jean-Bosco , Gatineau , PQ , J8Y 3G5 , Canada.
authors.forename: Larbi
authors.initials: L
authors.lastname: Talbi
authors.affiliation: Département d'informatique et d'ingénierie , Université du Québec en Outaouais , 101 Saint-Jean-Bosco , Gatineau , PQ , J8Y 3G5 , Canada.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Lakhssassi
authors.affiliation: Ciena Canada , 3500 Carling Avenue , Ottawa , ON , K2H 8E7 , Canada.
authors.forename: Sadok
authors.initials: S
authors.lastname: Aouini
keywords: Freiburg database; Lyapunov index; alpha subbands; beta subbands; biomedical electrodes; chaos; chaos theory; cross-correlation theory; delta subbands; electrodes; electroencephalography; electroencephalography signals; entropy; epileptic patients; false-positive rate; frequency 60 Hz to 120 Hz; gamma subbands; hippocampal area; medical disorders; medical signal processing; neurophysiology; patient monitoring; power spectral density; seizure signature; statistical analysis; temporal epilepsy seizure monitoring; temporal epilepsy seizure prediction; theta subbands; threshold levels; time 200 h