title: Dual Effect of Ziconotide in Primary Erythromelalgia.
abstract: Erythromelalgia (EM) is a rare disabling clinical syndrome more commonly known to affect the lower extremities. There is no single effective treatment for this disease that often requires a multidisciplinary approach. Herein, we report the case of a 31-year-old woman affected by primary erythromelalgia who was successfully treated with intrathecal Ziconotide. We also observed an unexpected result following therapy with Ziconotide. The legs and feet of the patient that at the time of admission were swollen and tumefied dramatically improved after one week of the drug administration.
authors.affiliation: Pain Therapy Unit, Department of Hematology and Oncology, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
authors.forename: Rosario
authors.initials: R
authors.lastname: Russo
authors.affiliation: Department of Pharmacy and Health and Nutritional Sciences, University of Calabria, Italy.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Caroleo
authors.affiliation: Department of Pharmacy and Health and Nutritional Sciences, University of Calabria, Italy.
authors.forename: Erika
authors.initials: E
authors.lastname: Cione
authors.affiliation: Department of Pharmacy and Health and Nutritional Sciences, University of Calabria, Italy.
authors.forename: Mariarita
authors.initials: M
authors.lastname: Perri
authors.affiliation: Molecular Biology Unit, Department of Hematology and Oncology, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Paparo
authors.affiliation: Molecular Biology Unit, Department of Hematology and Oncology, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Russo