title: Measles 50 Years After Use of Measles Vaccine.
abstract: In response to severe measles, the first measles vaccine was licensed in the United States in 1963. Widespread use of measles vaccines for more than 50 years has significantly reduced global measles morbidity and mortality. However, measles virus continues to circulate, causing infection, illness, and an estimated 400 deaths worldwide each day. Measles is preventable by vaccine, and humans are the only reservoir. Clinicians should promote and provide on-time vaccination for all patients and keep measles in their differential diagnosis of febrile rash illness for rapid case detection, confirmation of measles infection, isolation, treatment, and appropriate public health response.
authors.affiliation: Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, 1600 Clifton Road, Northeast, MS A-04, Atlanta, GA 30333, USA. Electronic address: jgoodson@cdc.gov.
authors.forename: James L
authors.initials: JL
authors.lastname: Goodson
authors.affiliation: Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Northeast, Atlanta, GA 30333, USA.
authors.forename: Jane F
authors.initials: JF
authors.lastname: Seward
mesh_terms: D019433:Chickenpox Vaccine / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000517:prevention & control; D004197:Disease Reservoirs / Q000821:virology; D005260:Female; D049670:History, 17th Century; D049671:History, 18th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007223:Infant; D008297:Male; D008457:Measles / Q000453:epidemiology / Q000266:history* / Q000517:prevention & control* / Q000821:virology; D008458:Measles Vaccine / Q000008:administration & dosage*; D008459:Measles virus / Q000276:immunology; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage; D014481:United States; D017778:Vaccines, Combined / Q000008:administration & dosage
chemical_list: D019433:Chickenpox Vaccine; D008458:Measles Vaccine; D022542:Measles-Mumps-Rubella Vaccine; D017778:Vaccines, Combined; C050102:measles, mumps, rubella, varicella vaccine
keywords: Exemptions; Fever; Measles elimination; Mortality; Rash; Vaccination; Vaccine preventable