title: Antibiotic use and good practice in 314 French hospitals: The 2010 SPA2 prevalence study.
abstract: OBJECTIVE
  We aimed to assess antibiotic prescriptions to identify potential targets for improvement.
  
  
  METHODS
  We conducted a point prevalence survey (November 2010) of antibiotic use in 314 voluntary hospitals recruited by the French Infectious Diseases Society (SPILF) and the National Observatory for Epidemiology of Bacterial Resistance to Antimicrobials (ONERBA). Data were entered online, immediately analyzed and exported.
  
  
  RESULTS
  The prevalence of antibiotic use was 19.5% (9059/46,446patients). A higher prevalence was observed in the infectious disease (58.4%), hematology (58%), and intensive care (48.7%) units. The three most frequently used antibiotic classes were aminopenicillins (23.8%), fluoroquinolones (17.9%), and 3rd-generation cephalosporins (16.7%). A monotherapy was prescribed to 64% of patients. The reasons for the antibiotic prescription were written in the medical records of 74% of patients and 62% were consistent with the local guidelines.
  
  
  CONCLUSIONS
  Our results are similar to that of other studies. Various local targets for improvement have been identified to help hospitals define a better antibiotic stewardship.
authors.affiliation: Service de réanimation et des maladies infectieuses, centre hospitalier Dron, 59208 Tourcoing, France. Electronic address: Alfandari.s@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Alfandari
authors.affiliation: Bactériologie et hygiène, hôpitaux universitaires de la Pitié-Salpêtrière - Charles-Foix, AP-HP, 75013 Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Robert
authors.affiliation: Observatoire national de l'épidémiologie de la résistance bactérienne aux antibiotiques (ONERBA), 75006 Paris, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Péan
authors.affiliation: Service des maladies infectieuses, CHU, 54511 Nancy, France.
authors.forename: C
authors.initials: C
authors.lastname: Rabaud
authors.affiliation: Service de réanimation, centre hospitalier Henri-Mignot, 78157 Le Chesnay, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Bedos
authors.affiliation: Laboratoire de bactériologie, HEGP, 75908 Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Varon
authors.affiliation: Service de réanimation, hôpital Sud, 69495 Lyon, France.
authors.forename: A
authors.initials: A
authors.lastname: Lepape
authors.affiliation: Service des maladies infectieuses, centre hospitalier de la région d'Annecy, 74374 Annecy, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Bru
authors.affiliation: Service d'anesthésie-réanimation chirurgicale, CHU Cochin, AP-HP, 75679 Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Gauzit
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D004363:Drug Utilization / Q000592:standards* / Q000706:statistics & numerical data*; D005260:Female; D005602:France; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotic stewardship; Antibiotics; Antibiotique; Audit; Bon usage