title: Iris metastasis from esophageal squamous cell carcinoma: A case report.
abstract: Carcinoma metastatic to the eye is a rare condition, typically associated with a poor prognosis. Breast and lung cancers are the most common sources of intraocular metastases, and the majority of metastatic lesions involve the posterior uvea, with <8% of reported cases arising in the iris. Intraocular metastasis as the presenting form of esophageal carcinoma is highly uncommon. In the present report, a rare case of metastatic iris tumor resulting from esophageal squamous cell carcinoma is discussed. A 64-year-old patient presented with a progressively distending pain in the right eye, with associated blurred vision. Local and systemic evaluation was performed, followed by treatment. Multiple examinations identified a neoplasm in the right iris and postoperative pathology revealed that the iris lesion was a metastasis of esophageal squamous cell cancer origin. The patient was treated with adjuvant radiation. To the best of our knowledge, this was only the second reported case of esophageal squamous cell carcinoma metastasizing to the iris.
authors.affiliation: Department of Clinical Oncology, The 105 Hospital of The People's Liberation Army, Hefei, Anhui 230031, P.R. China.
authors.forename: Donglai
authors.initials: D
authors.lastname: Lv
authors.affiliation: Department of Clinical Oncology, The 105 Hospital of The People's Liberation Army, Hefei, Anhui 230031, P.R. China.
authors.forename: Zongtao
authors.initials: Z
authors.lastname: Hu
authors.affiliation: Department of Clinical Oncology, The 105 Hospital of The People's Liberation Army, Hefei, Anhui 230031, P.R. China.
authors.forename: Chong
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Clinical Oncology, The 105 Hospital of The People's Liberation Army, Hefei, Anhui 230031, P.R. China.
authors.forename: Shile
authors.initials: S
authors.lastname: Gao
authors.affiliation: Department of Pathology, The 105 Hospital of The People's Liberation Army, Hefei, Anhui 230031, P.R. China.
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
keywords: esophageal cancer; iris metastasis; squamous cell carcinoma