title: A new way of quantifying diagnostic information from multilead electrocardiogram for cardiac disease classification.
abstract: A new measure for quantifying diagnostic information from a multilead electrocardiogram (MECG) is proposed. This diagnostic measure is based on principal component (PC) multivariate multiscale sample entropy (PMMSE). The PC analysis is used to reduce the dimension of the MECG data matrix. The multivariate multiscale sample entropy is evaluated over the PC matrix. The PMMSE values along each scale are used as a diagnostic feature vector. The performance of the proposed measure is evaluated using a least square support vector machine classifier for detection and classification of normal (healthy control) and different cardiovascular diseases such as cardiomyopathy, cardiac dysrhythmia, hypertrophy and myocardial infarction. The results show that the cardiac diseases are successfully detected and classified with an average accuracy of 90.34%. Comparison with some of the recently published methods shows improved performance of the proposed measure of cardiac disease classification.
authors.affiliation: Department of Electronics and Electrical Engineering , Indian Institute of Technology , Guwahati , Assam 781039 , India.
authors.forename: R K
authors.initials: RK
authors.lastname: Tripathy
authors.affiliation: Department of Electronics and Electrical Engineering , Indian Institute of Technology , Guwahati , Assam 781039 , India.
authors.forename: L N
authors.initials: LN
authors.lastname: Sharma
authors.affiliation: Department of Electronics and Electrical Engineering , Indian Institute of Technology , Guwahati , Assam 781039 , India.
authors.forename: S
authors.initials: S
authors.lastname: Dandapat
keywords: MECG data matrix; PMMSE; cardiac disease classification; cardiac dysrhythmia; cardiovascular disease; diagnostic feature vector; diagnostic information; diseases; electrocardiography; hypertrophy; least square classifier; medical diagnostic computing; medical signal processing; multilead electrocardiogram; multivariate multiscale sample entropy; myocardial infarction; principal component; principal component analysis; support vector machine classifier; support vector machines