title: Analysis of Multicontrast Carotid Plaque MR Imaging.
abstract: Plaque imaging by MR imaging provides a wealth of information on the characteristics of individual plaque that may reveal vulnerability to rupture, likelihood of progression, or optimal treatment strategy. T1-weighted and T2-weighted images among other options reveal plaque morphology and composition. Dynamic contrast-enhanced-MR imaging reveals plaque activity. To extract this information, image processing tools are needed. Numerous approaches for analyzing such images have been developed, validated against histologic gold standards, and used in clinical studies. These efforts are summarized in this article.
authors.affiliation: Department of Biomedical Engineering, Center for Biomedical Imaging Research, School of Medicine, Tsinghua University, Room No. 109, Haidian District, Beijing, China.
authors.forename: Huijun
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Biomedical Engineering, Center for Biomedical Imaging Research, School of Medicine, Tsinghua University, Room No. 120, Haidian District, Beijing, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Department of Radiology, School of Medicine, University of Washington, 850 Republican Street, Seattle, WA 98109, USA. Electronic address: bkerwin98136@yahoo.com.
authors.forename: William
authors.initials: W
authors.lastname: Kerwin
mesh_terms: D000465:Algorithms; D000818:Animals; D016893:Carotid Stenosis / Q000175:diagnosis*; D003198:Computer Simulation; D003287:Contrast Media; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D016247:Information Storage and Retrieval / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008955:Models, Cardiovascular; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media
keywords: Atherosclerosis; Biomechanics; Composition; Contrast enhancement; Image processing; MR imaging; Morphology