title: Use of surgical mesh of different compositions in the correction of the abdominal wall defect in rats.
abstract: OBJECTIVE
  To analyze the performance of two surgical meshes of different compositions during the defect healing process of the abdominal wall of rats.
  
  
  METHODS
  thirty-three adult Wistar rats were anesthetized and subjected to removal of an area of 1.5 cm x 2 cm of the anterior abdominal wall, except for the skin; 17 animals had the defect corrected by edge-to-edge surgical suture of a mesh made of polypropylene + poliglecaprone (Group U--UltraproTM); 16 animals had the defect corrected with a surgical mesh made of polypropylene + polidioxanone + cellulose (Group P--ProceedTM). Each group was divided into two subgroups, according to the euthanasia moment (seven days or 28 days after the operation). Parameters analyzed were macroscopic (adherence), microscopic (quantification of mature and immature collagen) and tensiometric (maximum tension and maximum rupture strength).
  
  
  RESULTS
  there was an increase in collagen type I in the ProceedTM group from seven to 28 days, p = 0.047. Also, there was an increase in the rupture tension on both groups when comparing the two periods. There was a lower rupture tension and tissue deformity with ProceedTM mesh in seven days, becoming equal at day 28.
  
  
  CONCLUSIONS
  the meshes retain similarities in the final result and more studies with larger numbers of animals must be carried for better assessment.
authors.affiliation: Universidade Federal do Paraná, Curitiba, PR, Brasil.
authors.forename: Ana Cristina
authors.initials: AC
authors.lastname: Isa
authors.affiliation: Universidade Federal do Paraná, Curitiba, PR, Brasil.
authors.forename: Jorge Eduardo Fouto
authors.initials: JE
authors.lastname: Matias
authors.affiliation: Universidade Federal do Paraná, Curitiba, PR, Brasil.
authors.forename: Celia Toshie
authors.initials: CT
authors.lastname: Yamamoto
authors.affiliation: Hospital Angelina Caron, Paraná, PR, Brasil.
authors.forename: Rosana Hapsi
authors.initials: RH
authors.lastname: Isa
authors.affiliation: Universidade Federal do Paraná, Curitiba, PR, Brasil.
authors.forename: Antônio Carlos Ligocki
authors.initials: AC
authors.lastname: Campos
authors.affiliation: Universidade Federal do Paraná, Curitiba, PR, Brasil.
authors.forename: Júlio Cezar Uili
authors.initials: JC
authors.lastname: Coelho
mesh_terms: D034861:Abdominal Wall / Q000601:surgery*; D000818:Animals; D001672:Biocompatible Materials; D011126:Polypropylenes; D051381:Rats; D017208:Rats, Wistar; D013526:Surgical Mesh
chemical_list: D001672:Biocompatible Materials; D011126:Polypropylenes