title: Loss of molars in periodontally treated patients: results 10 years and more after active periodontal therapy.
abstract: OBJECTIVE
  To identify risk factors for loss of molars during supportive periodontal therapy (SPT).
  
  
  METHODS
  A total of 136 subjects with 1015 molars at baseline were examined retrospectively. The association of risk factors with loss of molars was assessed using a multilevel Cox regression analysis. Furcation involvement (FI) was assessed clinically at start of periodontal therapy and assigned according to Hamp et al. (1975).
  
  
  RESULTS
  Fifty molars were extracted during active periodontal therapy (APT) and 154 molars over the average SPT period of 13.2 ± 2.8 years. FI degree III (HR 4.68, p < 0.001), baseline bone loss (BL) > 60% (HR 3.74, p = 0.009), residual mean probing pocket depth (PPD, HR 1.43, p = 0.027), and endodontic treatment (HR 2.98, p < 0.001) were identified as relevant tooth-related factors for loss of molars during SPT. However, mean survival time for molars with FI III or BL > 60% were 11.8 and 14.4 years, respectively. Among the patient data, age (HR 1.57, p = 0.01), female gender (HR 1.99, p = 0.035), smoking (HR 1.97, p = 0.034), and diabetes mellitus (HR 5.25, p = 0.021) were significant predictors for loss of molars.
  
  
  CONCLUSIONS
  Overall, periodontal therapy results in a good prognosis of molars. Degree III FI, progressive BL, endodontic treatment, residual PPD, age, female gender, smoking, and diabetes mellitus strongly influence the prognosis for molars after APT.
authors.affiliation: Section of Periodontology, Department of Conservative Dentistry, Clinic for Oral, Dental and Maxillofacial Diseases, University Hospital Heidelberg, Heidelberg, Germany.|Private Dental Practice, Weilburg, Germany.
authors.forename: Bettina
authors.initials: B
authors.lastname: Dannewitz
authors.affiliation: Section of Periodontology, Department of Conservative Dentistry, Clinic for Oral, Dental and Maxillofacial Diseases, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Anna
authors.initials: A
authors.lastname: Zeidler
authors.affiliation: Coordination Centre for Clinical Trials (KKS), University of Heidelberg, Heidelberg, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Hüsing
authors.affiliation: Institute of Medical Biometry and Informatics (IMBI), University of Heidelberg, Heidelberg, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Saure
authors.affiliation: Section of Endodontology, Department of Conservative Dentistry, Clinic for Oral, Dental and Maxillofacial Diseases, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Thorsten
authors.initials: T
authors.lastname: Pfefferle
authors.affiliation: Department of Periodontology, Center of Dentistry and Oral Medicine (Carolinum), Johann Wolfgang Goethe-University Frankfurt, Frankfurt, Germany.
authors.forename: Peter
authors.initials: P
authors.lastname: Eickholz
authors.affiliation: Section of Periodontology, Department of Conservative Dentistry, Clinic for Oral, Dental and Maxillofacial Diseases, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Bernadette
authors.initials: B
authors.lastname: Pretzl
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D017823:Furcation Defects; D006801:Humans; D008875:Middle Aged; D008963:Molar; D010514:Periodontal Pocket; D012189:Retrospective Studies; D016388:Tooth Loss; D016896:Treatment Outcome; D055815:Young Adult
keywords: furcation involvement; long-term; molar; supportive periodontal therapy; tooth loss