title: Sexual risk behaviors among HIV-patients receiving antiretroviral therapy in Southern Thailand: roles of antiretroviral adherence and serostatus disclosure.
abstract: The objective of this study was to examine the extent of unprotected sex among patients already established in HIV-medical care and their associated factors. Sexually active patients who were receiving antiretroviral therapy (ART) from five public hospitals in Trang province, Southern Thailand, were interviewed. Of 279 studied patients, 37.3% had unprotected sex in the prior 3 months and 27.2% did not disclose their serostatus to sexual partners. The median duration interquartile range (IQR) of using ART was 47 (27-60) months and 26.7% were non-adherent to ART (i.e., taking less than 95% of the prescribed doses). More than one-third had the perception that ART use would protect against HIV transmission even with unprotected sex. About 36.6% reported that they were unaware of their current CD4 counts and nearly one-third did not receive any safe sex counseling at each medical follow-up. After adjustment for potential confounders, non-adherence to ART and HIV-nondisclosure were strongly associated with an increase in the risk of unprotected sex with the adjusted odds ratio (aOR) of 5.03 (95% CI 2.68-9.44) and 3.89 (95% CI 1.57-9.61), respectively. In contrast, the risk for engaging in unprotected sex was less likely among patients having a negative-serostatus partner (aOR = 0.30; 95% CI 0.12-0.75), a longer duration of the use of ART (aOR = 0.98; 95%CI 0.97-0.99) and an unawareness of their current CD4 levels (aOR = 0.54; 95% CI 0.30-0.99). To maximize the benefits from ART, there should be a bigger emphasis on the "positive prevention" program and more efforts are needed to target the population at risk for unprotected sex. Strategies to encourage adherence to ART and for disclosure of serostatus are also required.
authors.affiliation: a Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences , Prince of Songkla University , Hatyai , Songkhla , Thailand.
authors.forename: Nattasiri
authors.initials: N
authors.lastname: Thanawuth
authors.affiliation: a Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences , Prince of Songkla University , Hatyai , Songkhla , Thailand.
authors.forename: Malee
authors.initials: M
authors.lastname: Rojpibulstit
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D003376:Counseling; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology*; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000453:epidemiology; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D055118:Medication Adherence; D012309:Risk-Taking; D012725:Sexual Behavior / Q000523:psychology*; D012747:Sexual Partners; D012959:Socioeconomic Factors; D013785:Thailand / Q000453:epidemiology; D014342:Truth Disclosure; D047568:Unsafe Sex / Q000706:statistics & numerical data*
keywords: HIV; Sexual risk behavior; adherence; antiretroviral therapy; serostatus disclosure