title: [Forensic Investigation of Goldeneye™ DNA ID 22NC Kit].
abstract: OBJECTIVE
  To investigate the genetic data of 21 autosomal STR included in Goldeneye™ DNA ID 22NC Kit in Chinese Han nationality and to evaluate the forensic application.
  
  
  METHODS
  By detected 500 unrelated healthy individuals in Chinese Han nationality of East China with Goldeneye™ DNA ID 22NC Kit, allele frequencies, population genetics parameters and linkage disequilibrium information of the 21 autosomal STR were statistically analyzed.
  
  
  RESULTS
  In the 21 autosomal STR, no deviations from Hardy-Weinberg equilibrium were detected and all loci were independent form each other. DP values of 21 autosomal STR were all above 0.85, and the combined discrimination power was 1-3.616 5 x 10(-26). Combined mean exclusion chance of this system in duo cases was 1-2.786 81 x10(-6), in trio cases was 1-8.545 82 x 10(-1).
  
  
  CONCLUSIONS
  Twenty-one autosomal STR included in Goldeneye™ DNA ID 22NC Kit are highly polymorphic in the Han nationality. Combined with Goldeneye™ DNA ID 20A Kit, the kit can satisfy the needs for full-sibling testing and facilitate the solution of this kind of case tools.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Lin
authors.forename: Ting-zhi
authors.initials: TZ
authors.lastname: Que
authors.forename: Zhen-min
authors.initials: ZM
authors.lastname: Zhao
authors.forename: Su-hua
authors.initials: SH
authors.lastname: Zhang
mesh_terms: D000483:Alleles; D044466:Asian People / Q000208:ethnology / Q000235:genetics*; D002681:China; D005006:Ethnicity / Q000235:genetics; D053803:Forensic Genetics / Q000379:methods*; D005787:Gene Frequency; D056426:Genetic Loci / Q000235:genetics*; D005819:Genetic Markers / Q000235:genetics; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D011110:Polymorphism, Genetic; D011933:Reagent Kits, Diagnostic
chemical_list: D005819:Genetic Markers; D011933:Reagent Kits, Diagnostic