title: Results of a multicenter prospective phase II trial investigating the safety and efficacy of lenalidomide in patients with myelodysplastic syndromes with isolated del(5q) (LE-MON 5).
authors.affiliation: Department for Hematology, Oncology and Clinical Immunology, University Hospital, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Schuler
authors.affiliation: Department of Hematology, Oncology and Palliative Care, Marien Hospital Duesseldorf, Duesseldorf, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Giagounidis
authors.affiliation: University Medicine Goettingen, Clinics of Hematology and Medical Oncology, Goettingen, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Haase
authors.affiliation: University Medicine Goettingen, Clinics of Hematology and Medical Oncology, Goettingen, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Shirneshan
authors.affiliation: Hannover Medical School, Institute of Pathology, Hannover, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Büsche
authors.affiliation: Department of Hematology, University Hospital Dresden, Dresden, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Platzbecker
authors.affiliation: Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Nolte
authors.affiliation: Department of Internal Medicine, Technical University of Munich, Munich, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Götze
authors.affiliation: Department of Internal Medicine, University Hospital Ulm, Ulm, Germany.
authors.forename: R F
authors.initials: RF
authors.lastname: Schlenk
authors.affiliation: Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Ganser
authors.affiliation: Department of Hematology and Oncology, Charité, Benjamin Franklin University, Berlin, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Letsch
authors.affiliation: University Medicine Goettingen, Clinics of Hematology and Medical Oncology, Goettingen, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Braulke
authors.affiliation: University Hospital Freiburg, Internal Medicine, Freiburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Lübbert
authors.affiliation: Department of Internal Medicine, University Hospital Frankfurt, Frankfurt, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Bug
authors.affiliation: Department of Oncology, Hematology, BMT with section Pneumology, Hubertus Wald Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Schafhausen
authors.affiliation: University Medicine Goettingen, Clinics of Hematology and Medical Oncology, Goettingen, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Bacher
authors.affiliation: Department for Hematology, Oncology and Clinical Immunology, University Hospital, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Gattermann
authors.affiliation: Department for Hematology, Oncology and Clinical Immunology, University Hospital, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Wulfert
authors.affiliation: Department for Hematology, Oncology and Clinical Immunology, University Hospital, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Haas
authors.affiliation: Department for Hematology, Oncology and Clinical Immunology, University Hospital, Heinrich-Heine-University, Duesseldorf, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Germing
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002872:Chromosome Deletion; D002895:Chromosomes, Human, Pair 5 / Q000235:genetics; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D053208:Kaplan-Meier Estimate; D000077269:Lenalidomide; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000188:drug therapy* / Q000235:genetics / Q000401:mortality; D016016:Proportional Hazards Models; D011446:Prospective Studies; D013792:Thalidomide / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D007155:Immunologic Factors; D013792:Thalidomide; D000077269:Lenalidomide