title: Two new indole alkaloids from Hunteria zeylanica.
abstract: Two new indole alkaloids, 14β-hydroperoxy-eburnamine (1) and 18α-hydroxy-eburnamine (2), together with three known indole alkaloids, (-)-eburnamonine (3), (-)-eburnamenine (4), and eburnamine (5) were isolated from Hunteria zeylanica collected in Hainan Province of China. Their structures were determined by spectroscopic analysis. The relative configuration of 2 was deduced by NOE experiment and evidenced by the calculations for energy minimization with the molecular modeling program Chem3D Ultra 10.0.
authors.affiliation: a State Key Laboratory of Grassland Agro-Ecosystems, College of Pastoral Agriculture Science and Technology , Lanzhou University , Lanzhou 730020 , China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Liu
authors.affiliation: b State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering , Lanzhou University , Lanzhou 730000 , China.
authors.forename: Chao-Jun
authors.initials: CJ
authors.lastname: Chen
authors.affiliation: b State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering , Lanzhou University , Lanzhou 730000 , China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.affiliation: b State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering , Lanzhou University , Lanzhou 730000 , China.
authors.forename: Kun
authors.initials: K
authors.lastname: Gao
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D008958:Models, Molecular; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D014748:Vinca Alkaloids / Q000737:chemistry
chemical_list: C000610018:14beta-hydroperoxy-eburnamine; D026121:Indole Alkaloids; D014748:Vinca Alkaloids; C016422:eburnamonine
keywords: Apocynaceae; Hunteria zeylanica; alkaloids; eburnamine