title: Effect of Tributyrin on Electrical Activity in the Small Intestine during Early Postoperative Period.
abstract: The effect of enteral administration of tributyrin on electrical activity in the upper segments of the small intestine was examined in rats on the model of postoperative ileus. This postoperative state is characterized with pronounced and long-term disturbances in generation of migrating myoelectric complex of the small intestine. The enteral administration of tributyrin in the early postoperative period aimed to suppress the non-adrenergic non-cholinergic influences and activation of the cholinergic anti-inflammatory pathways is an effective procedure to normalize the migrating myoelectric complex and therefore the coordinated propulsive peristalsis in the small intestine.
authors.affiliation: N. V. Sklifosovsky Research Institute of Emergency Medicine, Ministry of Health of the Russian Federation, Moscow, Russia. ntropskaya@mail.ru.
authors.forename: N S
authors.initials: NS
authors.lastname: Tropskaya
authors.affiliation: N. V. Sklifosovsky Research Institute of Emergency Medicine, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Kislyakova
authors.affiliation: N. V. Sklifosovsky Research Institute of Emergency Medicine, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: T S
authors.initials: TS
authors.lastname: Popova
mesh_terms: D000818:Animals; D045823:Ileus / Q000378:metabolism; D007421:Intestine, Small / Q000187:drug effects*; D008297:Male; D016065:Myoelectric Complex, Migrating / Q000187:drug effects; D011184:Postoperative Period; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000494:pharmacology*
chemical_list: D014280:Triglycerides; C005830:tributyrin
keywords: migrating myoelectric complex; postoperative ileus; small intestine; tributyrin