title: Catalytic asymmetric formal γ-allylation of deconjugated butenolides.
abstract: A formal γ-allylation of deconjugated butenolides is reported based on a two-step sequence consisting of a catalytic diastereo- and enantioselective vinylogous nucleophilic addition to vinyl sulfones and Julia-Kocienski olefination. This highly modular approach delivers densely functionalized butenolides containing a quaternary stereogenic centre in excellent yield with high enantioselectivity.
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India. sm@orgchem.iisc.ernet.in.
authors.forename: Amit K
authors.initials: AK
authors.lastname: Simlandy
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India. sm@orgchem.iisc.ernet.in.
authors.forename: Santanu
authors.initials: S
authors.lastname: Mukherjee