title: Efficacy of PD-1 blockade in tumors with MMR deficiency.
authors.affiliation: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, 1650 Orleans Street, Room 407, Baltimore, MD 21287, USA.
authors.forename: Valerie
authors.initials: V
authors.lastname: Lee
authors.affiliation: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, 1650 Orleans Street, Room 407, Baltimore, MD 21287, USA.
authors.forename: Dung T
authors.initials: DT
authors.lastname: Le
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D020137:Base Pair Mismatch; D001932:Brain Neoplasms; D015179:Colorectal Neoplasms; D006801:Humans; D007167:Immunotherapy; D000067552:Mutation Accumulation; D009369:Neoplasms / Q000235:genetics / Q000276:immunology / Q000378:metabolism / Q000628:therapy; D009386:Neoplastic Syndromes, Hereditary; D061026:Programmed Cell Death 1 Receptor / Q000037:antagonists & inhibitors / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; C105992:PDCD1 protein, human; D061026:Programmed Cell Death 1 Receptor
keywords: immune checkpoint inhibition; microsatellite instability; mismatch repair deficiency