title: Multiscale study of bacterial growth: Experiments and model to understand the impact of gas exchange on global growth.
abstract: Using a millifluidics and macroscale setup, we study quantitatively the impact of gas exchange on bacterial growth. In millifluidic environments, the permeability of the incubator materials allows an unlimited oxygen supply by diffusion. Moreover, the efficiency of diffusion at small scales makes the supply instantaneous in comparison with the cell division time. In hermetic closed vials, the amount of available oxygen is low. The growth curve has the same trend but is quantitatively different from the millifluidic situation. The analysis of all the data allows us to write a quantitative modeling enabling us to capture the entire growth process.
authors.affiliation: University of Bordeaux, CNRS, Solvay, LOF UMR 5258, France.
authors.forename: David
authors.initials: D
authors.lastname: Lalanne-Aulet
authors.affiliation: University of Bordeaux, CNRS, Solvay, LOF UMR 5258, France.
authors.forename: Adalberto
authors.initials: A
authors.lastname: Piacentini
authors.affiliation: University of Bordeaux, CNRS, Solvay, LOF UMR 5258, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Guillot
authors.affiliation: Solvay, Centre de Recherches de Lyon, 85 rue des Frères Perret, Saint-Fons, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Marchal
authors.affiliation: Solvay, Centre de Recherches de Lyon, 85 rue des Frères Perret, Saint-Fons, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Moreau
authors.affiliation: ESPCI, CNRS, SIMM UMR 7615, 11 rue Vauquelin, 75005 Paris, France.
authors.forename: Annie
authors.initials: A
authors.lastname: Colin
mesh_terms: D002455:Cell Division / Q000187:drug effects; D004058:Diffusion; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects* / Q000254:growth & development* / Q000378:metabolism; D008954:Models, Biological; D010100:Oxygen / Q000378:metabolism / Q000494:pharmacology*; D010539:Permeability; D013211:Staphylococcus aureus / Q000166:cytology / Q000187:drug effects* / Q000254:growth & development* / Q000378:metabolism
chemical_list: D010100:Oxygen