title: [COCONUT OIL: NON-ALTERNATIVE DRUG TREATMENT AGAINST ALZHEIMER´S DISEASE].
abstract: BACKGROUND
  Alzheimer's dementia is the most prevalent nowadays. As for treatment, there is no definitive cure drug, thus new therapies are needed. In this regard the medium chain triglycerides are a direct source of cellular energy and can be a nonpharmacological alternative to the neuronal death for lack of it, that occurs in Alzheimer patients.
  
  
  OBJECTIVE
  to evaluate the impact of coconut oil in the development of Alzheimer's dementia, in any degree of dementia. Also determine whether this improvement influences within variables such as sex and suffering or not Type II Diabetes Mellitus.
  
  
  METHODS
  a prospective study was conducted in patients with Alzheimer's dementia, with a control and an intervention group which was administered 40 ml/day of extra virgin coconut oil. The parameters evaluated were the mini test scores Lobo cognitive test, pre and post intervention in both groups.
  
  
  RESULTS
  it was observed in subjects taking the product, a statistically significant increase in test score MECWOLF and therefore an improvement in cognitive status, improving especially women's, those without diabetes mellitus type II, and severe patients.
  
  
  CONCLUSIONS
  this study, although preliminary, demonstrated the positive influence of coconut oil at the cognitive level of patients with Alzheimer's, this improvement being dependent on sex, presence or absence of diabetes and degree of dementia.
authors.affiliation: Universidad Católica de Valencia.. joseenrique.delarubia@uev.es.
authors.forename: Iván
authors.initials: I
authors.lastname: Hu Yang
authors.affiliation: Universidad Europea de Valencia.. joseenrique.delarubia@uev.es.
authors.forename: Jose Enrique
authors.initials: JE
authors.lastname: De la Rubia Ortí
authors.affiliation: Hospital Universitario Morales Meseguer.. joseenrique.delarubia@uev.es.
authors.forename: Pablo
authors.initials: P
authors.lastname: Selvi Sabater
authors.affiliation: Universidad Católica de Valencia.. joseenrique.delarubia@uev.es.
authors.forename: Sandra
authors.initials: S
authors.lastname: Sancho Castillo
authors.affiliation: Universidad de Valencia. España.. joseenrique.delarubia@uev.es.
authors.forename: Mariano Julián
authors.initials: MJ
authors.lastname: Rochina
authors.affiliation: Hospital Universitario Morales Meseguer.. joseenrique.delarubia@uev.es.
authors.forename: Noemí
authors.initials: N
authors.lastname: Manresa Ramón
authors.affiliation: Universidad de Valencia. España.. joseenrique.delarubia@uev.es.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Montoya-Castilla
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000517:prevention & control* / Q000523:psychology; D000074263:Coconut Oil; D003071:Cognition / Q000187:drug effects; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010938:Plant Oils / Q000627:therapeutic use*; D011446:Prospective Studies
chemical_list: D010938:Plant Oils; D000074263:Coconut Oil