title: The role of BMI change on smoking abstinence in a sample of HIV-infected smokers.
abstract: The prevalence of cigarette smoking among persons living with HIV/AIDS (PLWHA) is approximately 40%, significantly higher than that of the general population. Identifying predictors of successful smoking cessation for PLWHA is necessary to alleviate the morbidity and mortality associated with smoking in this population. Weight gain has been associated with smoking relapse in the general population, but has not been studied among PLWHA. Data from 474 PLWHA enrolled in a smoking cessation randomized clinical trial were analyzed to examine the effect of BMI change, from baseline to 3-month follow-up, on smoking outcomes using multiple logistic regression. The odds of 7-day smoking abstinence at 3-month follow-up were 4.22 (95% CI = 1.65, 10.82) times higher for participants classified as BMI decrease and 4.22 (95% CI = 1.62, 11.01) times higher for participants classified as BMI increase as compared to participants with a minimal increase or decrease in BMI. In this sample, both weight gain and loss following smoking cessation were significantly associated with abstinence at 3-month follow-up among HIV-infected smokers. Further research and a better understanding of predictors of abstinence will encourage more tailored interventions, with the potential to reduce morbidity and mortality.
authors.affiliation: a Department of Behavioral Science , MD Anderson Cancer Center , Houston , TX , USA.
authors.forename: Meredith K
authors.initials: MK
authors.lastname: Buchberg
authors.affiliation: a Department of Behavioral Science , MD Anderson Cancer Center , Houston , TX , USA.
authors.forename: Ellen R
authors.initials: ER
authors.lastname: Gritz
authors.affiliation: a Department of Behavioral Science , MD Anderson Cancer Center , Houston , TX , USA.
authors.forename: George
authors.initials: G
authors.lastname: Kypriotakis
authors.affiliation: b Department of Internal Medicine , University of Texas Health Science Center at Houston , Houston , TX , USA.
authors.forename: Roberto C
authors.initials: RC
authors.lastname: Arduino
authors.affiliation: c Department of Family and Preventative Medicine , The University of Oklahoma Health Sciences Center , Oklahoma City , OK , USA.
authors.forename: Damon J
authors.initials: DJ
authors.lastname: Vidrine
mesh_terms: D000328:Adult; D001521:Behavior Therapy / Q000379:methods*; D001828:Body Image; D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation / Q000379:methods*; D016896:Treatment Outcome; D015430:Weight Gain
keywords: BMI; HIV; body image; obesity; smoking cessation