title: Gross motor function and general development of babies born after assisted reproductive technology.
abstract: OBJECTIVE
  To elucidate the gross motor function and general development of babies born after assisted reproductive technology (ART).
  
  
  METHODS
  The study subjects comprised 238 babies born after ART and 365 babies as the control. Multiple births, premature and low birth weight babies were excluded. Questionnaires were distributed to mothers and gross motor function and general development were evaluated according to the Ability for Basic Movement Scale for Children (ABMS-C) and Kinder Infant Development Scale (KIDS), respectively.
  
  
  RESULTS
  There were no significant differences in gross motor function according to the ABMS-C between the two groups at one, three, six, nine and 12 months of age. The KIDS scores on subscales of expressive language at three months, manipulation at nine months and the total developmental quotient, and subscales of manipulation, receptive language and social relationships with children at 12 months were significantly higher in the ART than in the control group.
  
  
  CONCLUSIONS
  There was no significant difference in gross motor function up to 12 months of age between the ART and control groups. However, the total developmental quotient and scores on linguistic and communication capacity of children at 12 months of age were significantly higher in the ART group. These results suggested that ART has no adverse effects on intellectual function, at least during early infancy.
authors.affiliation: Division of Rehabilitation Medicine and Developmental Evaluation Center.
authors.forename: Keiji
authors.initials: K
authors.lastname: Hashimoto
authors.affiliation: Center of Maternal-Fetal and Neonatal Medicine.
authors.forename: Kohei
authors.initials: K
authors.lastname: Ogawa
authors.affiliation: Division of Endocrinology and Metabolism, National Center for Child Health and Development, Tokyo, Japan.
authors.forename: Reiko
authors.initials: R
authors.lastname: Horikawa
authors.affiliation: Division of Rehabilitation Medicine and Developmental Evaluation Center.
authors.forename: Natsuha
authors.initials: N
authors.lastname: Ikeda
authors.affiliation: Division of Rehabilitation Medicine and Developmental Evaluation Center.
authors.forename: Keiko
authors.initials: K
authors.lastname: Kato
authors.affiliation: Division of Rehabilitation Medicine and Developmental Evaluation Center.
authors.forename: Anri
authors.initials: A
authors.lastname: Kamide
authors.affiliation: Center of Maternal-Fetal and Neonatal Medicine.
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Sago
mesh_terms: D002657:Child Development / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D027724:Reproductive Techniques, Assisted
keywords: Ability for Basic Movement Scale for Children (ABMS-C); Kinder Infant Development Scale (KIDS); assisted reproductive technology (ART); gross motor function; questionnaire survey