title: Prediction of short-term newborn infectious morbidity based on maternal characteristics in patients with PPROM and Ureaplasma species infection.
abstract: OBJECTIVE
  Preterm premature rupture of membranes (PPROM) complicates about 5% of pregnancies. Ureaplasma species is the most common pathogen found in the amniotic fluid in pregnancieneonatal outcome. The aim of the following study was to evaluate the impact of colonization with the Ureaplasma spp. on pregnant women with PPROM, coin fection with different microorganisms, and antimicrobial treatment on neonatal outcome.
  
  
  METHODS
  The study included 30 women with PPROM hospitalized in Division of Reproduction in s complicated by PPROM. It is speculated that it requires a coin fection to produce unfavorable Poznan's K. Marcinkowski University of Medical Sciences. Swabs from cenvical canal were obtained for the identifidation of bacterial and ureaplasma tic infections by culture and POR.
  
  
  RESULTS
  The presence of any infection during the pregnancy a fter PP ROM was con firmed in 22 patients (Ureaplasma spp. in 12 patients, coin fection in 10 women). The cure rate for Ureaplasma species and other infections was 17% (2/12 patients) and 23% (5/22 patients), respectively There was no correlation between Ureaplasma species infection, coin fection, and cure status with the infection in the newborn. The PPROM to delivery duration also did not affect the newborn infection status. A negative relationship with leukocyte level was detected in patient with newborn infection.
  
  
  CONCLUSIONS
  The presence of colonization with Ureaplasma species is not attributable to neonatal short-term morbidity The evaluation of maternal biochemical and microbiological data, regardless of the duration of the pregnancy after PPROM or the cure status, does not add any insight into the newborn infection status.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Mikołajczyk
authors.forename: Przemysław Krzysztof
authors.initials: PK
authors.lastname: Wirstlein
authors.forename: Magdalena
authors.initials: M
authors.lastname: Wróbel
authors.forename: Jan
authors.initials: J
authors.lastname: Mazela
authors.forename: Karolina
authors.initials: K
authors.lastname: Chojnacka
authors.forename: Jana
authors.initials: J
authors.lastname: Skrzypezak
mesh_terms: D000653:Amniotic Fluid / Q000382:microbiology; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy / Q000382:microbiology*; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D007752:Obstetric Labor, Premature / Q000382:microbiology; D011044:Poland; D011247:Pregnancy; D011379:Prognosis; D012307:Risk Factors; D014509:Ureaplasma / Q000302:isolation & purification*; D016869:Ureaplasma Infections / Q000188:drug therapy / Q000382:microbiology*