title: Antiviral properties of caffeic acid phenethyl ester and its potential application.
abstract: Caffeic acid phenethyl ester (CAPE) is found in a variety of plants and well-known the active ingredient of the honeybee propolis. CAPE showed anti-inflammatory, anticarcinogenic, antimitogenic, antiviral, and immunomodulatory properties in several studies. The beneficial effects of CAPE on different health issues attracted scientists to make more studies on CAPE. Specifically, the anti-viral effects of CAPE and its molecular mechanisms may reveal the important properties of virus-induced diseases. CAPE and its targets may have important roles to design new therapeutics and understand the molecular mechanisms of virus-related diseases. In this mini-review, we summarize the antiviral effects of CAPE under the light of medical and chemical literature.
authors.affiliation: Department of Biochemistry Laboratory, Corum Training and Research Hospital, Corum, Turkey.
authors.forename: Hacı Kemal
authors.initials: HK
authors.lastname: Erdemli
authors.affiliation: Department of Medical Biology, Faculty of Medicine, Turgut Ozal University, Ankara, Turkey.
authors.forename: Sumeyya
authors.initials: S
authors.lastname: Akyol
authors.affiliation: Department of Medical Biochemistry, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors.forename: Ferah
authors.initials: F
authors.lastname: Armutcu
authors.affiliation: Department of Medical Biochemistry, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Omer
authors.initials: O
authors.lastname: Akyol
keywords: Antiviral effect; caffeic acid phenethyl ester; caffeic acid phenethyl ester-like compounds