title: Cherubism With Bilateral Mandible and Maxilla Involvement: A Case Report.
abstract: Cherubism is a rare, nonneoplastic, self-limiting fibro-osseous that occurs in children. Affected children usually appear normal at birth. Lesions are characterized by the replacement of bone with fibrovascular tissue containing many multinucleated giant cells. Most studies have reported cherubism to be familial and with bilateral involvement of the mandibles. The authors describe a nonfamilial case of cherubism, involving both the mandible and the maxilla, in a 4-year-old female child with slowly enlarging, painless, symmetrical swelling of both cheeks.Cherubism is a rare disease that is usually limited to the mandible, but the maxilla may be involved. Computed tomography scan and biopsy are helpful for early diagnosis.
authors.affiliation: From the Department of Radiology and Pharmacy, Shandong Power Central Hospital (ZY, MZ, WG, HZ, HW); and Department of Gynaecology and Obstetrics, Women and Children Health Care Hospital of Shandong Province, Shandong, China (YZ).
authors.forename: Zhaoyang
authors.initials: Z
authors.lastname: Yu
authors.forename: Miao
authors.initials: M
authors.lastname: Zhai
authors.forename: Wei
authors.initials: W
authors.lastname: Gan
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Yuxia
authors.initials: Y
authors.lastname: Zhou
authors.forename: Haixia
authors.initials: H
authors.lastname: Wen
mesh_terms: D002636:Cherubism / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D014057:Tomography, X-Ray Computed