title: Genotoxic and mutagenic effects of sewage sludge on higher plants.
abstract: Sewage treatment yields sludge, which is often used as a soil amendment in agriculture and crop production. Although the sludge contains elevated concentrations of macro and micronutrients, high levels of inorganic and organic compounds with genotoxic and mutagenic properties are present in sludge. Application of sludge in agriculture is a pathway for direct contact of crops to toxic chemicals. The objective of this study was to compile information related to the genotoxic and mutagenic effects of sewage sludge in different plant species. In addition, data are presented on toxicological effects in animals fed with plants grown in soils supplemented with sewage sludge. Despite the benefits of using sewage sludge as organic fertilizer, the data showcased in this review suggest that this residue can induce genetic damage in plants. This review alerts potential risks to health outcomes after the intake of food cultivated in sewage sludge-amended soils.
authors.affiliation: Programa de Pós-Graduação em Genética e Melhoramento, Centro de Ciências Agrárias, Universidade Federal do Espírito Santo, CEP 29500-000 Alegre, ES, Brazil.
authors.forename: Maria Nilza
authors.initials: MN
authors.lastname: Corrêa Martins
authors.affiliation: Departamento de Biologia, Centro de Ciências Agrárias, Universidade Federal do Espírito Santo, CEP 29500-000 Alegre, ES, Brazil.
authors.forename: Victor Ventura
authors.initials: VV
authors.lastname: de Souza
authors.affiliation: Programa de Pós-Graduação em Genética e Melhoramento, Centro de Ciências Agrárias, Universidade Federal do Espírito Santo, CEP 29500-000 Alegre, ES, Brazil; Departamento de Biologia, Centro de Ciências Agrárias, Universidade Federal do Espírito Santo, CEP 29500-000 Alegre, ES, Brazil. Electronic address: tatianas.souza@hotmail.com.
authors.forename: Tatiana da Silva
authors.initials: TDS
authors.lastname: Souza
mesh_terms: D000383:Agriculture; D000818:Animals; D032461:Chromosomes, Plant / Q000187:drug effects*; D018556:Crops, Agricultural / Q000187:drug effects*; D005308:Fertilizers / Q000009:adverse effects*; D017343:Genes, Plant / Q000187:drug effects; D018977:Micronutrients; D009153:Mutagens / Q000633:toxicity; D017354:Point Mutation; D012722:Sewage / Q000009:adverse effects* / Q000737:chemistry; D012987:Soil; D012989:Soil Pollutants / Q000633:toxicity*
chemical_list: D005308:Fertilizers; D018977:Micronutrients; D009153:Mutagens; D012722:Sewage; D012987:Soil; D012989:Soil Pollutants
keywords: Biosolid; Genotoxicity; Plants; Sludge-amended soil