title: Interventions for Rosacea.
abstract: OBJECTIVE
  Which interventions are associated with highest efficacy and fewest adverse events for treating rosacea?
  
  
  CONCLUSIONS
  There is high-quality evidence that topical brimonidine, azelaic acid, and ivermectin, as well as oral doxycycline and isotretinoin, are associated with improvements in rosacea. Lower-quality evidence is available for topical metronidazole, oral tetracycline, laser and light-based therapy, and topical cyclosporine for ocular rosacea. Most treatments are not associated with higher adverse event rates than placebo.
authors.affiliation: Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands.
authors.forename: Esther J
authors.initials: EJ
authors.lastname: van Zuuren
authors.affiliation: Bahrain Branch of Cochrane, Awali, Bahrain.
authors.forename: Zbys
authors.initials: Z
authors.lastname: Fedorowicz
mesh_terms: D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D012393:Rosacea / Q000188:drug therapy*
chemical_list: D003879:Dermatologic Agents