title: Chondro-osseous respiratory epithelial adenomatoid hamartoma of the nasal cavity.
abstract: Chondro-osseous respiratory epithelial adenomatoid hamartoma is a rare hamartomatous lesion of the nasal cavity, with only five cases reported in the literature to date. We report the case of a 3-year-old boy who presented with nasal obstruction and a mass in the left nasal cavity. The mass was completely resected on endoscopy. On microscopy, hamartomatous proliferation of respiratory-type glands admixed with islands of immature hyaline cartilage, characteristic of chondro-osseous respiratory epithelial adenomatoid hamartoma, was seen. Neither local recurrence nor distant metastasis was observed after 6 month follow up. Recognition of chondro-osseous respiratory epithelial adenomatoid hamartoma as a benign lesion is important to avoid unnecessary surgical procedures.
authors.affiliation: Departments of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.|Department of Otolaryngology Head and Neck Surgery, Beijing DiTan Hospital, Capital Medical University, Beijing, China.|Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
authors.forename: Gaoli
authors.initials: G
authors.lastname: Fang
authors.affiliation: Departments of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.|Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
authors.forename: Chengshuo
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Pathology, Beijing TongRen Hospital, Capital Medical University, Beijing, China.
authors.forename: Yingshi
authors.initials: Y
authors.lastname: Piao
authors.affiliation: Departments of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China.|Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
authors.forename: Luo
authors.initials: L
authors.lastname: Zhang
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D004724:Endoscopy; D006222:Hamartoma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D009296:Nasal Cavity / Q000000981:diagnostic imaging*; D009668:Nose Diseases / Q000175:diagnosis*; D020545:Respiratory Mucosa / Q000473:pathology; D014057:Tomography, X-Ray Computed
keywords: chondro-osseous respiratory epithelial adenomatoid hamartoma; nasal cavity; nasal chondromesenchymal hamartoma; respiratory epithelial adenomatoid hamartoma