title: [A GENETIC VIEW OF FAMILIAL HYPERCHOLESTEROLEMIA].
abstract: OBJECTIVE
  to show reviewed information of published studies relating to Familial Hypercholesterolemia (FH), nutrition, and genes involved in the development of this pathology.
  
  
  RESULTS
  an analysis showing familial hypercholesterolemia as a disorder occuring due to mutations in gene encoding of the LDL receptor, which can be transmitted as an autosomal dominant or autosomal recessive. It's diagnosis is important for those with a greater likelihood of premature coronary disease, and can significantly reduce life expectancy.
  
  
  CONCLUSIONS
  there are no specific clinical criteria with absolute predictive value for the diagnosis of HF, Genetic diagnosis can prove functional defects in the LDL receptor gene, constituting definitive confirmation of the diagnosis, thus the importance of presenting a genetic vision of development of this disease, which can be treated adequately through diet therapy affecting future generations in the family concerned.
authors.affiliation: Unidad de Bioquímica e Inmunología ITO-UNAM (Oaxaca), Oaxaca. Centro de Investigación UNAM-UABJO (Oaxaca), Oaxaca. Escuela de Nutrición, URSE (Oaxaca), Oaxaca. México.. snipermontalvo@gmail.com.
authors.forename: Diana
authors.initials: D
authors.lastname: Matías-Pérez
authors.affiliation: Unidad de Bioquímica e Inmunología ITO-UNAM (Oaxaca), Oaxaca. Centro de Investigación UNAM-UABJO (Oaxaca), Oaxaca.. snipermontalvo@gmail.com.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Pérez-Campos
authors.affiliation: Unidad de Bioquímica e Inmunología ITO-UNAM (Oaxaca), Oaxaca. Centro de Investigación UNAM-UABJO (Oaxaca), Oaxaca.. snipermontalvo@gmail.com.
authors.forename: Iván Antonio
authors.initials: IA
authors.lastname: García-Montalvo
mesh_terms: D005820:Genetic Testing; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000175:diagnosis / Q000235:genetics*; D011973:Receptors, LDL / Q000235:genetics
chemical_list: D011973:Receptors, LDL