title: Novel Functions of Renin Precursors in Homeostasis and Disease.
abstract: Renin progenitors appear early and are found in multiple tissues throughout the embryo. Besides their well known role in blood pressure and fluid homeostasis, renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses. In the bone marrow, renin cells offer clues to understand normal and neoplastic hematopoiesis.
authors.affiliation: University of Virginia School of Medicine, Child Health Research Center, Charlottesville, Virginia rg@virginia.edu msl7u@virginia.edu.
authors.forename: R Ariel
authors.initials: RA
authors.lastname: Gomez
authors.affiliation: University of Virginia School of Medicine, Child Health Research Center, Charlottesville, Virginia rg@virginia.edu msl7u@virginia.edu.
authors.forename: Maria Luisa S
authors.initials: ML
authors.lastname: Sequeira-Lopez
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000502:physiology; D001853:Bone Marrow / Q000378:metabolism / Q000502:physiology; D006410:Hematopoiesis / Q000502:physiology; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000378:metabolism / Q000503:physiopathology; D012083:Renin / Q000378:metabolism*; D012084:Renin-Angiotensin System / Q000502:physiology*
chemical_list: D012083:Renin