title: Differences in clinical characteristics for the determination of adenomyosis coexisting with leiomyomas.
abstract: OBJECTIVE
  The objective of the analysis was to determine the characteristics that distinguish women with adenomyosis and leiomyomas from those with leiomyoma only from a sample who underwent hysterectomy for benign uterine diseases.
  
  
  METHODS
  This retrospective study was based on the analysis of medical records of 75 women with both adenomyosis and uterine leiomyomas and 218 women with leiomyomas only, diagnosed by histologic analysis of uterine specimens.
  
  
  RESULTS
  Results of multivariate logistic regression analyses showed that women with both adenomyosis and leiomyomas had a higher gravity (odds ratio [OR] 1.16, 95% confidence interval [CI] 1.01-1.33) and more frequent pelvic pain (OR 0.38, 95% CI 0.21-0.7) compared with women with leiomyomas only. Postmenopausal bleeding was commonly reported in women with adenomyosis and leiomyomas. No significant difference was observed between the two groups in terms of menorrhagia and metrorrhagia and the preoperative diagnosis of prolapse.
  
  
  CONCLUSIONS
  The presence of concomitant adenomyosis may cause different clinical symptomatology.
authors.affiliation: Faculty of Medicine, Department of Obstetrics and Gynecology, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Seda
authors.initials: S
authors.lastname: Ates
authors.affiliation: Faculty of Medicine, Department of Obstetrics and Gynecology, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Ozcan
authors.affiliation: Faculty of Medicine, Department of Obstetrics and Gynecology, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Aydin
authors.affiliation: Faculty of Medicine, Department of Obstetrics and Gynecology, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Nilay
authors.initials: N
authors.lastname: Karaca
mesh_terms: D062788:Adenomyosis / Q000453:epidemiology / Q000503:physiopathology*; D000328:Adult; D015897:Comorbidity; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000453:epidemiology / Q000503:physiopathology*; D008875:Middle Aged; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000453:epidemiology / Q000503:physiopathology*
keywords: adenomyosis; hysterectomy; leiomyoma; pelvic pain; risk factors