title: MEDICAL MANAGEMENT OF LEIOMYOMATA AND SUSPECTED ENDOMETRIOSIS IN AN ALLEN'S SWAMP MONKEY (ALLENOPITHECUS NIGROVIRIDUS).
abstract: A 13-yr-old female nulliparous Allen's swamp monkey (Allenopitchecus nigroviridis) presented with intermittent excessive vaginal bleeding, cyclical lethargy, and a history of irregular menstrual cycles. Abdominal ultrasonography revealed a subjectively thickened, irregular endometrium, multiple leiomyomata (uterine fibroids), and bilateral anechoic foci on the ovaries. Treatment was initiated with leuprolide acetate i.m. monthly for 6 mo. Recheck ultrasound at 3 mo showed a decrease in leiomyoma diameter and no evidence of active follicles on the ovaries. Eleven months following completion of treatment, clinical signs recurred and the animal was treated with a deslorelin implant. Since implant placement, no vaginal bleeding has been noted.
authors.forename: Yousuf S
authors.initials: YS
authors.lastname: Jafarey
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Hanley
authors.forename: Ric A
authors.initials: RA
authors.lastname: Berlinski
authors.forename: Connie
authors.initials: C
authors.lastname: Warner
authors.forename: Anthony
authors.initials: A
authors.lastname: Armstrong
mesh_terms: D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D016663:Cercopithecinae; D004343:Drug Implants; D004715:Endometriosis / Q000662:veterinary*; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology; D005260:Female; D007889:Leiomyoma / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D016729:Leuprolide / Q000627:therapeutic use; D008992:Monkey Diseases / Q000188:drug therapy* / Q000473:pathology; D017329:Triptorelin Pamoate / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology
chemical_list: D018931:Antineoplastic Agents, Hormonal; D004343:Drug Implants; D004791:Enzyme Inhibitors; D017329:Triptorelin Pamoate; D016729:Leuprolide; C066438:deslorelin
keywords: Allen's swamp monkey (Allenopitchecus nigroviridis); GnRH analog; endometriosis; leiomyoma; leuprolide acetate