title: Submicrometer-Sized Thermometer Particles Exploiting Selective Nucleic Acid Stability.
abstract: Encapsulated nucleic acid selective damage quantification by real-time polymerase chain reaction is used as sensing mechanism to build a novel class of submicrometer size thermometer. Thanks to the high thermal and chemical stability, and the capability of storing the read accumulated thermal history, the sensor overcomes some of current limitations in small scale thermometry.
authors.affiliation: Institute of Chemical and Bioengineering, ETH Zurich, Vladimir-Prelog-Weg, 8093, Zurich, Switzerland.
authors.forename: Michela
authors.initials: M
authors.lastname: Puddu
authors.affiliation: Institute of Chemical and Bioengineering, ETH Zurich, Vladimir-Prelog-Weg, 8093, Zurich, Switzerland.
authors.forename: Gediminas
authors.initials: G
authors.lastname: Mikutis
authors.affiliation: Institute of Chemical and Bioengineering, ETH Zurich, Vladimir-Prelog-Weg, 8093, Zurich, Switzerland.
authors.forename: Wendelin J
authors.initials: WJ
authors.lastname: Stark
authors.affiliation: Institute of Chemical and Bioengineering, ETH Zurich, Vladimir-Prelog-Weg, 8093, Zurich, Switzerland.
authors.forename: Robert N
authors.initials: RN
authors.lastname: Grass
mesh_terms: D002138:Calibration; D004247:DNA / Q000737:chemistry; D009696:Nucleic Acids / Q000737:chemistry*; D010316:Particle Size; D012313:RNA / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry; D013821:Thermometers
chemical_list: D009696:Nucleic Acids; D012313:RNA; D012822:Silicon Dioxide; D004247:DNA
keywords: deoxyribonucleic acid; nucleic acids; polymerase chain reactions; ribonucleic acid; silica; temperature