title: Hepatic manifestations of non-steroidal inflammatory bowel disease therapy.
abstract: Inflammatory bowel disease (IBD) is composed of Crohn's disease and ulcerative colitis and is manifested by both bowel-related and extraintestinal manifestations. Recently the number of therapeutic options available to treat IBD has dramatically increased, with each new medication having its own mechanism of action and side effect profile. A complete understanding of the hepatotoxicity of these medications is important in order to distinguish these complications from the hepatic manifestations of IBD. This review seeks to evaluate the hepatobiliary complications of non-steroid based IBD medications and aide providers in the recognition and management of these side-effects.
authors.affiliation: Robert Hirten, Keith Sultan, Ashby Thomas, David E Bernstein, Division of Gastroenterology, North Shore University Hospital-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Robert
authors.initials: R
authors.lastname: Hirten
authors.affiliation: Robert Hirten, Keith Sultan, Ashby Thomas, David E Bernstein, Division of Gastroenterology, North Shore University Hospital-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Keith
authors.initials: K
authors.lastname: Sultan
authors.affiliation: Robert Hirten, Keith Sultan, Ashby Thomas, David E Bernstein, Division of Gastroenterology, North Shore University Hospital-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Ashby
authors.initials: A
authors.lastname: Thomas
authors.affiliation: Robert Hirten, Keith Sultan, Ashby Thomas, David E Bernstein, Division of Gastroenterology, North Shore University Hospital-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: David E
authors.initials: DE
authors.lastname: Bernstein
keywords: Adverse drug reactions; Crohn’s disease; Drug induced liver injury; Hepatotoxicity; Inflammatory bowel disease; Ulcerative colitis