title: Pd-Catalyzed Asymmetric Decarboxylative Cycloaddition of Vinylethylene Carbonates with Imines.
abstract: An efficient method for the enantioselective synthesis of β-tertiary β-amino alcohol derivatives through Pd-catalyzed decarboxylative cycloaddition of vinylethylene carbonates with imines was developed. By using a palladium complex generated in situ from [Pd2(dba)3]·CHCl3 and phosphoramidite L2 as a catalyst under mild reaction conditions, the process provided 4-substituted-4-vinyloxazolidines in good to high yields with high levels of enantio- and diastereoselectivities.
authors.affiliation: School of Chemistry and Chemical Engineering and Shanghai Key Laboratory of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.|Key Laboratory for Organism Resources of the Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, Yanbian University , 977 Gongyuan Road, Yanji, Jilin 133002, P. R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Yang
authors.affiliation: School of Chemistry and Chemical Engineering and Shanghai Key Laboratory of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
authors.forename: Ajmal
authors.initials: A
authors.lastname: Khan
authors.affiliation: School of Chemistry and Chemical Engineering and Shanghai Key Laboratory of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
authors.forename: Renfeng
authors.initials: R
authors.lastname: Zheng
authors.affiliation: Key Laboratory for Organism Resources of the Changbai Mountain and Functional Molecules, Ministry of Education, and Department of Chemistry, Yanbian University , 977 Gongyuan Road, Yanji, Jilin 133002, P. R. China.
authors.forename: Long Yi
authors.initials: LY
authors.lastname: Jin
authors.affiliation: School of Chemistry and Chemical Engineering and Shanghai Key Laboratory of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai 200240, P. R. China.
authors.forename: Yong Jian
authors.initials: YJ
authors.lastname: Zhang