title: Characterization of a Novel Composite Staphylococcal Cassette Chromosome mec in Methicillin-Resistant Staphylococcus pseudintermedius from Thailand.
abstract: A novel staphylococcal cassette chromosome mec (SCCmec) composite island (SCCmecAI16-SCCczrAI16-CI) was identified in Staphylococcus pseudintermedius. Four integration site sequences for SCC subdivided the 60,734-bp island into 41,232-bp SCCmecAI16, 19,400-bp SCCczrAI16, and 102-bp SCC-likeAI16 elements. SCCmecAI16 represents a new combination of ccrA1B3 genes with a class A mec complex. SCCczrAI16 contains ccrA1B6 and genes related to restriction modification and heavy metal resistance. SCCmecAI16-SCCczrAI16-CI was found in methicillin-resistant S. pseudintermedius sequence type 112 (ST112) and ST111 isolated from dogs and veterinarians in Thailand.
authors.affiliation: Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Pattrarat
authors.initials: P
authors.lastname: Chanchaithong
authors.affiliation: Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Nuvee
authors.initials: N
authors.lastname: Prapasarakul
authors.affiliation: Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland vincent.perreten@vetsuisse.unibe.ch.
authors.forename: Vincent
authors.identifier: http://orcid.org/0000-0001-5722-9445
authors.initials: V
authors.lastname: Perreten
authors.affiliation: Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
authors.forename: Sybille
authors.initials: S
authors.lastname: Schwendener
mesh_terms: D000818:Animals; D002876:Chromosomes, Bacterial; D004283:Dog Diseases / Q000382:microbiology; D004285:Dogs; D005798:Genes, Bacterial; D016106:Methicillin Resistance / Q000235:genetics*; D013203:Staphylococcal Infections / Q000382:microbiology / Q000662:veterinary; D013210:Staphylococcus / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D013785:Thailand