title: Therapeutic Application of Bone Marrow-Derived Stem Cells in a Patient with Methanol-Induced Blindness.
abstract: OBJECTIVE
  To report bone marrow derived stem cell application in a patient with bilateral visual loss due to accidental ingestion of methanol.
  
  
  METHODS
  A 22-year-old male patient with bilateral visual loss at discharge after treatment for methanol ingestion was treated with retrobulbar and intrathecal autologus bone marrow derived stem cells in an outpatient setting. The procedure was followed by Vit B12 Injection 500 mcg alternate days and oral vitamins B1, B2, B6, in therapeutic dose for 3 months.
  
  
  RESULTS
  The patient demonstrated favorable outcome three days after the treatment. Visual acuity improved to 20/20 in both eyes by third week.
  
  
  CONCLUSIONS
  Treatment with retrobulbar and intrathecal autologous bone marrow derived stem cell in an adult male patient with bilateral visual loss due to accidental ingestion of methanol was effective. Larger studies are warranted to explore the real impact of this procedure.
authors.forename: Himanshu
authors.initials: H
authors.lastname: Bansal
authors.forename: Anupama
authors.initials: A
authors.lastname: Bansal
authors.forename: M Neelam
authors.initials: MN
authors.lastname: Kachhap
authors.forename: Abhay
authors.initials: A
authors.lastname: Chowdhary
authors.forename: Prasad S
authors.initials: PS
authors.lastname: Koka
mesh_terms: D001766:Blindness / Q000139:chemically induced / Q000473:pathology / Q000628:therapy*; D001854:Bone Marrow Cells / Q000166:cytology* / Q000502:physiology; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000502:physiology; D006801:Humans; D056965:Injections, Intraocular; D007278:Injections, Spinal; D008297:Male; D000432:Methanol / Q000633:toxicity; D020127:Recovery of Function / Q000502:physiology*; D012256:Riboflavin / Q000627:therapeutic use; D013831:Thiamine / Q000627:therapeutic use; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014805:Vitamin B 12 / Q000627:therapeutic use; D025101:Vitamin B 6 / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D025101:Vitamin B 6; D014805:Vitamin B 12; D012256:Riboflavin; D013831:Thiamine; D000432:Methanol