title: Treating morbid obesity in cirrhosis: A quest of holy grail.
abstract: The problem of obesity is increasing worldwide in epidemic proportions; the situation is similarly becoming more common in patients with cirrhosis which negatively affect the prognosis of disease and also makes liver transplantation difficult especially in the living donor liver transplantation setting where low graft to recipient weight ratio negatively affects survival. Treatment of obesity is difficult in cirrhosis due to difficulty in implementation of lifestyle measures, limited data on safety of anti-obesity drugs and high risk of surgery. Currently approved anti-obesity drugs have limited data in patients with cirrhosis. Bariatric surgery remains an option in selected compensated cirrhotic patients. Endoscopic interventions for obesity are emerging and are quite promising in patients with cirrhosis as these are minimally invasive. In present review, we briefly discuss various modalities of weight reduction in obese patients and their applicability in patients with cirrhosis.
authors.affiliation: Naveen Kumar, Narendra Singh Choudhary, Department of Transplant Hepatology, Medanta Liver Institute, Medanta the Medicity, Gurgaon 122001, Haryana, India.
authors.forename: Naveen
authors.initials: N
authors.lastname: Kumar
authors.affiliation: Naveen Kumar, Narendra Singh Choudhary, Department of Transplant Hepatology, Medanta Liver Institute, Medanta the Medicity, Gurgaon 122001, Haryana, India.
authors.forename: Narendra Singh
authors.initials: NS
authors.lastname: Choudhary
keywords: Antiobesity drugs; Bariatric surgery; Cirrhosis; Intragastric balloon; Obesity