title: An Investigation of (Diacetoxyiodo)arenes as Precursors for Preparing No-Carrier-Added [(18)F]Fluoroarenes from Cyclotron-Produced [(18)F]Fluoride Ion.
abstract: Treatment of (diacetoxyiodo)arenes (1a-1u) with cyclotron-produced [(18)F]fluoride ion rapidly affords no-carrier-added [(18)F]fluoroarenes (2a-2u) in useful yields and constitutes a new method for converting substituted iodoarenes into substituted [(18)F]fluoroarenes in just two steps.
authors.affiliation: Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health , Building 10, Room B3 C346A, 10 Center Drive, Bethesda, Maryland 20892-1003, United States.
authors.forename: Mohammad B
authors.initials: MB
authors.lastname: Haskali
authors.affiliation: Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health , Building 10, Room B3 C346A, 10 Center Drive, Bethesda, Maryland 20892-1003, United States.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Telu
authors.affiliation: Center for Molecular Modeling, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health , Building 12A, Room 2049, 12 South Drive, Bethesda, Maryland 20892-5624, United States.
authors.forename: Yong-Sok
authors.initials: YS
authors.lastname: Lee
authors.affiliation: Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health , Building 10, Room B3 C346A, 10 Center Drive, Bethesda, Maryland 20892-1003, United States.
authors.forename: Cheryl L
authors.initials: CL
authors.lastname: Morse
authors.affiliation: Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health , Building 10, Room B3 C346A, 10 Center Drive, Bethesda, Maryland 20892-1003, United States.
authors.forename: Shuiyu
authors.initials: S
authors.lastname: Lu
authors.affiliation: Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health , Building 10, Room B3 C346A, 10 Center Drive, Bethesda, Maryland 20892-1003, United States.
authors.forename: Victor W
authors.initials: VW
authors.lastname: Pike
mesh_terms: D017357:Cyclotrons; D005459:Fluorides / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D005462:Fluorine Radioisotopes / Q000737:chemistry*; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D009861:Onium Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D049268:Positron-Emission Tomography
chemical_list: D005462:Fluorine Radioisotopes; D007462:Iodobenzenes; D009861:Onium Compounds; D005461:Fluorine; D005459:Fluorides