title: ACR-ASNR Practice Parameter for Brain PET/CT Imaging Dementia.
abstract: This practice parameter is for both FDG and amyloid brain PET or PET/computed tomography (CT) for patients with cognitive decline, and has been developed collaboratively by the American College of Radiology (ACR) and the American Society for Neuroradiology (ASNR). It is estimated that the number of people with dementia, 36.5 million worldwide in 2010, will increase to 65.7 million in 2030 and to 115 million in 2050. Four primary neurodegenerative etiologies of dementia have been defined: Alzheimer disease (AD), vascular dementia, frontotemporal dementia (FTD), and dementia with Lewy bodies (DLB). Alzheimer disease is the most common form of dementia, accounting for approximately 60%-80% of all cases. Indications for FDG and amyloid brain PET and qualifications for personnel are discussed in this practice parameter.
authors.affiliation: From the *Department of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, MI; †Outpatient Center, Johns Hopkins University, Baltimore, MD; ‡Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA; §Eka Medical Center, Jakarta, Indonesia; ∥UNC Department of Radiology, Chapel Hill, NC; ¶Neuroradiology Section, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA; **Division of Neuroradiology, Department of Radiology, Duke University Medical Center, Durham, NC; ††Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine; and ‡‡Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institution, Baltimore, MD.
authors.forename: Kirk A
authors.initials: KA
authors.lastname: Frey
authors.forename: Martin A
authors.initials: MA
authors.lastname: Lodge
authors.forename: Carolyn Cidis
authors.initials: CC
authors.lastname: Meltzer
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Peller
authors.forename: Terence Z
authors.initials: TZ
authors.lastname: Wong
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Hess
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Petrella
authors.forename: Haris I
authors.initials: HI
authors.lastname: Sair
authors.forename: Rathan M
authors.initials: RM
authors.lastname: Subramaniam
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D003704:Dementia / Q000000981:diagnostic imaging*; D006801:Humans; D064847:Multimodal Imaging / Q000009:adverse effects / Q000379:methods / Q000592:standards*; D049268:Positron-Emission Tomography / Q000009:adverse effects / Q000379:methods / Q000592:standards*; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000009:adverse effects; D014057:Tomography, X-Ray Computed / Q000009:adverse effects / Q000379:methods / Q000592:standards*
chemical_list: D019275:Radiopharmaceuticals