title: Validation of the 15-item myasthenia gravis quality of life questionnaire (MG-QOL15) Persian version.
abstract: The 15-item Myasthenia Gravis Quality Of Life (MG-QOL15) questionnaire is a valid and reliable instrument for evaluation of myasthenia gravis (MG) associated disability. Our study aim was to assess its validity and reliability in the Iranian population.
  
  
  
  We enrolled 75 consecutive patients with established MG at 2 neuromuscular clinics in Tehran, Iran. All 75 patients completed the Persian MG-QOL15 and SF-36 questionnaire initially, and 30 filled out the MG-QOL15 questionnaire from 2 to 4 weeks after the initial visit. Concurrent and construct validity, internal consistency, and test-retest repeatability of the questionnaire were evaluated.
  
  
  
  The Persian MG-QOL15 showed satisfactory internal consistency (Cronbach alpha = 0.94) and test-retest reliability(r = 0.98; P < 0.001). It also demonstrated adequate concurrent and construct validity; moreover, the MG-QOL15 scores were higher in patients with more severe conditions.
  
  
  
  The Persian MG-QOL15 is a valid and reliable questionnaire for determination of quality of life in Iranian MG patients. Muscle Nerve 54: 65-70, 2016.
authors.affiliation: Iranian Center of Neurological Research, Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, North Kargar Street, Tehran, Iran, 14117-13135.
authors.forename: Vahid Reza
authors.initials: VR
authors.lastname: Ostovan
authors.affiliation: Iranian Center of Neurological Research, Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, North Kargar Street, Tehran, Iran, 14117-13135.
authors.forename: Farzad
authors.initials: F
authors.lastname: Fatehi
authors.affiliation: Department of Community Medicine, Iran University of Medical sciences, Tehran, Iran.
authors.forename: Farnoush
authors.initials: F
authors.lastname: Davoudi
authors.affiliation: Iranian Center of Neurological Research, Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, North Kargar Street, Tehran, Iran, 14117-13135.
authors.forename: Shahriar
authors.initials: S
authors.lastname: Nafissi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000523:psychology*; D017063:Outcome Assessment, Health Care; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D014175:Translating
keywords: Farsi; Iran; MG-QOL15; SF36; clinical severity; myasthenia gravis; quality of life