title: Visit-to-visit blood pressure variability and dementia.
abstract: Visit-to-visit blood pressure variability has been shown to be an independent risk factor for stroke and cognitive impairment. However, the underlying mechanisms are not fully understood. Artery remodeling and silent cerebral injury are suggested to be involved in the relationship between visit-to-visit blood pressure variability and cognitive impairment. The present review article summarizes the recent literature on these topics. Here we review visit-to-visit blood pressure variability, artery remodeling, silent cerebral injury and an issue regarding the impact of these components on dementia including Alzheimer's disease.
authors.affiliation: Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
authors.forename: Michiaki
authors.initials: M
authors.lastname: Nagai
authors.affiliation: Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hoshide
authors.affiliation: Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
authors.forename: Keigo
authors.initials: K
authors.lastname: Dote
authors.affiliation: Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan.
authors.forename: Kazuomi
authors.initials: K
authors.lastname: Kario
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D000544:Alzheimer Disease / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D001794:Blood Pressure / Q000502:physiology; D018660:Blood Pressure Monitoring, Ambulatory; D003072:Cognition Disorders / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D003704:Dementia / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D015577:Geriatric Assessment / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000175:diagnosis; D015994:Incidence; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D009819:Office Visits / Q000706:statistics & numerical data*; D011379:Prognosis; D018570:Risk Assessment; D020521:Stroke / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D013997:Time Factors
keywords: Alzheimer's disease; Hypertension; cognitive impairment; stroke; visit-to-visit blood pressure variability