title: Functional Nausea in Children.
abstract: Chronic nausea is a highly prevalent, bothersome, and difficult-to-treat symptom among adolescents. When chronic nausea presents as the predominant symptom and is not associated with any underlying disease, it may be considered a functional gastrointestinal disorder and named "functional nausea." The clinical features of functional nausea and its association with comorbid conditions provide clues to the underlying pathophysiological mechanisms. These may include gastrointestinal motor and sensory disturbances, autonomic imbalance, altered central nervous system pathways, or a combination of these. This review summarizes the current knowledge on mechanisms and treatment strategies for chronic, functional nausea in children.
authors.affiliation: *Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Center for Pediatric Neurogastroenterology, Motility, and Autonomic Disorders, Medical College of Wisconsin, Milwaukee †Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Nationwide Children's Hospital, Columbus, OH.
authors.forename: Katja
authors.initials: K
authors.lastname: Kovacic
authors.forename: Carlo
authors.initials: C
authors.lastname: Di Lorenzo
mesh_terms: D000293:Adolescent; D000932:Antiemetics / Q000627:therapeutic use; D002648:Child; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005767:Gastrointestinal Diseases / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D009325:Nausea / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy
chemical_list: D000932:Antiemetics