title: Pasteurella multocida Infective Endocarditis: A Possible Link with Primary Upper Respiratory Tract Infection.
abstract: A 50-year-old Japanese man presented with fever and upper respiratory tract symptoms that required urgent inpatient admission. A physical examination revealed conjunctival hemorrhages and peripheral embolic phenomena. Blood cultures grew Pasteurella multocida, and an echocardiography revealed a mitral valve vegetation suggestive of infective endocarditis (IE), which was confirmed using the Modified Duke Criteria. After several antibiotic regimens proved ineffective, valve replacement was performed, with a good eventual outcome. P. multocida IE is rare and may sometimes have no preceding risk factors. P. multocida infections of the upper respiratory tract are unusual but may be an inciting event for IE. It is essential to check blood cultures and to repeat the performance of physical examinations to appreciate the developing features of IE.
authors.affiliation: Department of General Internal Medicine, Shonan Kamakura General Hospital, Japan.
authors.forename: Joel
authors.initials: J
authors.lastname: Branch
authors.forename: Takuya
authors.initials: T
authors.lastname: Kakutani
authors.forename: Shun
authors.initials: S
authors.lastname: Kuroda
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shiba
authors.forename: Izumi
authors.initials: I
authors.lastname: Kitagawa
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000382:microbiology; D010326:Pasteurella Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery*; D016979:Pasteurella multocida; D010808:Physical Examination; D012141:Respiratory Tract Infections / Q000382:microbiology; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents