title: [In Process Citation].
abstract: Diagnosis and treatment of HBV/HDV infection means for the patient to be able to maintain working capacity, to increase quality of life, to prevent cancer, and to prolong life expectancy, while society benefits from eliminating the chances of further transmission of the viruses, and decreasing the overall costs of serious complications. The guideline delineates the treatment algorithms for 2016 set by a consensus meeting of physicians involved in the treatment of these diseases. The prevalence of HBV infection in the Hungarian general population is 0.5-0.7%. The indications of treatment is based upon viral examinations (including viral nucleic acid determination), determinations of disease activity and stage (including biochemical, pathologic, and/or non-invasive methods), and excluding contraindications. To avoid unnecessary side effects and for cost-effective approach the guideline stresses the importance of quick and detailed virologic evaluations, the applicability of elastography as an acceptable alternative of liver biopsy in this regard, as well as the relevance of appropriate consistent follow up schedule for viral response during therapy. The first choice of therapy in chronic hepatitis B infection can be pegylated interferon for 48 weeks or continuous ente- cavir or tenofovir therapy. The latter two must be continued for at least 12 months after hepatitis B surface antigen seroconversion. Adefovir dipivoxil is recommended mainly in combination therapy. Lamivudine is no longer a first choice; patients currently taking lamivudine must switch if response is inadequate. Appropriate treatment of patients taking immunosuppressive medications is highly recommended. Pegylated interferon based therapy is recommended for the treatment of concomitant hepatitis D infection. Orv. Hetil., 2015, 156(Suppl. 2) 25-36.
authors.affiliation: Hepatológiai Szakambulancia, Budai Hepatológiai Centrum, Budapest, Szent János Kórház és Észak-budai Egyesített Kórházak Budapest, Egry József u. 1-3. 1111.
authors.forename: Gábor
authors.initials: G
authors.lastname: Horváth
authors.affiliation: Transzplantációs és Sebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.
authors.forename: Zsuzsanna
authors.initials: Z
authors.lastname: Gerlei
authors.affiliation: I. Belgyógyászati Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.
authors.forename: Judit
authors.initials: J
authors.lastname: Gervain
authors.affiliation: II. Belgyógyászati Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Lengyel
authors.affiliation: Egyesített Szent István és Szent László Kórház Budapest.
authors.forename: Mihály
authors.initials: M
authors.lastname: Makara
authors.affiliation: I. Belgyógyászati Klinika, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs.
authors.forename: Alajos
authors.initials: A
authors.lastname: Pár
authors.affiliation: I. Belgyógyászati Osztály, MH Egészségügyi Központ Honvédkórház Budapest.
authors.forename: László
authors.initials: L
authors.lastname: Rókusz
authors.affiliation: I. Belgyógyászati Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.
authors.forename: Ferenc
authors.initials: F
authors.lastname: Szalay
authors.affiliation: Orvos- és Egészségtudományi Centrum, Belgyógyászati Intézet, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen.
authors.forename: István
authors.initials: I
authors.lastname: Tornai
authors.affiliation: II. Belgyógyászati Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.
authors.forename: Klára
authors.initials: K
authors.lastname: Werling
authors.affiliation: I. Belgyógyászati Klinika, Pécsi Tudományegyetem, Általános Orvostudományi Kar Pécs.|Belgyógyászati Osztály, Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Béla
authors.initials: B
authors.lastname: Hunyady
keywords: adefovir; cirrhosis; entecavir; hepatitis B virus; hepatitis B-vírus; hepatitis D virus; hepatitis D-vírus; interferon; lamivudin; lamivudine; liver cancer; májrák; májzsugor; pegilált interferon; pegylated interferon; tenofovir; viral hepatitis; vírushepatitis