title: The Gene Pool: The Ethics of Genetics in Primary Care.
abstract: OBJECTIVE
  The purpose of this integrative review is to critically analyze the research literature regarding ethical principles that surround the integration of genetics and genomics in primary care clinical practice.
  
  
  BACKGROUND
  Advanced practice nurses (APRNs) play an important role in the provision of primary care services, in the areas of obstetrics, pediatrics, family practice, and internal medicine. Advances in genetic and genomic science are infiltrating these day-to-day health-care systems and becoming an integral part of health-care delivery. It is imperative for primary care providers to understand the ethical, legal, and social implications of genetics and genomics.
  
  
  METHODS
  A comprehensive multistep search of CINAHL, MEDLINE, Academic Search Premier, PsycINFO, Web of Science, and Scopus databases was conducted to identify primary research articles published from 2003 to 2015 that evaluated ethical issues related to genetics and genomics in U. S. primary care practice. A sample of 26 primary research articles met the inclusion criteria. Whittemore and Knafl's (2005) revised framework for integrative reviews was used to guide the analysis and assess the quality of the studies. Key findings from the studies are discussed according to Beauchamp and Childress's (2009) ethical principles of autonomy, beneficence, nonmaleficence, and justice.
  
  
  RESULTS
  Research conducted to date is mainly qualitative and descriptive and the analysis revealed several ethical challenges to implementing genetics and genomics in primary care settings.
  
  
  CONCLUSIONS
  The review suggests that there are several implications for research, education, and the development of primary care practice that support APRNs delivering genetic and genomic care while incorporating knowledge of ethical principles. More research needs to be conducted that evaluates the actual genetic/genomic ethical issues encountered by primary care providers.
authors.forename: Karen J
authors.initials: KJ
authors.lastname: Whitt
authors.forename: McKenna
authors.initials: M
authors.lastname: Hughes
authors.forename: Elizabeth Betsy S
authors.initials: EB
authors.lastname: Hopkins
authors.forename: Ann
authors.initials: A
authors.lastname: Maradiegue
mesh_terms: D057179:Advanced Practice Nursing / Q000941:ethics; D004993:Ethics, Nursing; D005788:Gene Pool; D005826:Genetics, Medical / Q000941:ethics*; D023281:Genomics / Q000941:ethics*; D006801:Humans; D011320:Primary Health Care / Q000941:ethics*