title: Reactive electrospinning of degradable poly(oligoethylene glycol methacrylate)-based nanofibrous hydrogel networks.
abstract: A direct, all-aqueous electrospinning method for fabricating degradable nanofibrous hydrogel networks is reported in which hydrazide and aldehyde-functionalized poly(oligoethylene glycol methacrylate) (POEGMA) polymers are simultaneously electrospun and cross-linked. The resulting networks are spatially well-defined, mechanically stable (both dry and wet), and offer extremely fast swelling responses, suggesting potential utility as smart hydrogels and tunable tissue engineering matrices.
authors.affiliation: Department of Chemical Engineering, McMaster University, 1280 Main St. W., Hamilton, Ontario L8S 4L7, Canada. hoaretr@mcmaster.ca.
authors.forename: Fei
authors.initials: F
authors.lastname: Xu
authors.affiliation: Department of Chemical Engineering, McMaster University, 1280 Main St. W., Hamilton, Ontario L8S 4L7, Canada. hoaretr@mcmaster.ca.
authors.forename: Heather
authors.initials: H
authors.lastname: Sheardown
authors.affiliation: Department of Chemical Engineering, McMaster University, 1280 Main St. W., Hamilton, Ontario L8S 4L7, Canada. hoaretr@mcmaster.ca.
authors.forename: Todd
authors.initials: T
authors.lastname: Hoare
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D020100:Hydrogels; D057139:Nanofibers; D011092:Polyethylene Glycols / Q000737:chemistry*
chemical_list: D000179:Acrylates; D020100:Hydrogels; C000609723:poly((oligoethylene glycol)acrylate); D011092:Polyethylene Glycols