title: [Infection of Mice with Normal Immune Function by Taenia asiatica].
abstract: The Taenia asiatica eggs pre-incubated with sodium hypochlorite solution for 4 min, 6 min and 8 mins were subcutaneously injected into mice with normal immune function(groups Al-A3 respectively, n=20 in each) and mice with immunosuppression (groups B1-B3, n=20 in each). All groups of mice began to show body discomfort on day 5 after infection and develop lumps on the back about on day 15. In groups Al-A3, animal death occurred during days 7-15, with a same survival rate of 95.0%(19/20) and infection rate of 89.4%(17/19), 73.6%(14/19) and 47.3%(9/19) respectively. In groups B1-B3, animal death occurred during days 7-50, with survival rate of 60%(13/20), 55%(11/20)and 55%(11/20) and infection rate of 76.9% (10/13), 54.5% (6/11) and 45.4% (5/11) respectively. After the scolex of cysticercus was evaginated with 15% pig bile, four suckers, an apparent rostellum and two distinct hook-like puncta structures were seen. These results indicate that mice with normal immune function can be used as a replacement of immunosuppressive mice to establish a T. asiatica oncosphere infection model. In addition, the T. asiatica eggs pre-incubated with sodium hypochlorite solution for 4 min have the strongest infection ability.
authors.forename: Xiao-yan
authors.initials: XY
authors.lastname: Liu
authors.forename: Guang-wu
authors.initials: GW
authors.lastname: Guo
authors.forename: Li-hong
authors.initials: LH
authors.lastname: Chen
authors.forename: Xing-ze
authors.initials: XZ
authors.lastname: Mo
authors.forename: Yue-sheng
authors.initials: YS
authors.lastname: Yu
mesh_terms: D000818:Animals; D007108:Immune Tolerance; D051379:Mice; D034421:Sus scrofa; D013552:Swine; D013621:Taenia; D013622:Taeniasis