title: Does Contrast Enhanced Ultrasound improve the management of liver abscesses? A single centre experience.
abstract: Liver abscess is a potentially lethal condition that requires prompt recognition and adequate treatment for a good outcome. The aim of this study was to assess the value of contrast enhanced ultrasound (CEUS) in the management of liver abscesses in the clinical practice of a single centre.
  
  
  METHODS
  A retrospective analysis was performed including all patients diagnosed with liver abscesses during 5 years (2010-2014) in a tertiary Department of Gastroenterology and Hepatology. The demographic data, the presence of risk factors, the cause of liver abscess, the B-mode conventional US aspect, the CEUS appearance and the patient's outcome were documented and analyzed.
  
  
  RESULTS
  The study group included 41 patients diagnosed with liver abscesses (17 women and 24 men, mean age 63.3+/-13.2 years), 16/41 (39%) of them with diabetes mellitus. A single lesion was found in 28 (68.3%) patients, and 13 (31.7%) patients had multiple abscesses. The CEUS study was conclusive for the diagnosis of liver abscess in clinical context in 38/41 cases (92.7%). All conclusive cases presented rim enhancement in the arterial phase and no enhancement in the liquid areas. The honeycomb appearance with septa enhancement was present in 17/41 (41.5%) patients. Washout of the marginal rim was found in 22/41 (53.6%) lesions.
  
  
  CONCLUSIONS
  In our group the most frequent CEUS features found were the rim enhancement in the arterial phase and the presence of no enhancement areas, followed by the honeycomb appearance. CEUS was able to be conclusive for the diagnosis of liver abscess in almost 93% of cases.
authors.affiliation: Department of Gastroneterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy Timisoara, Romania. alinamircea.popescu@gmail.com.
authors.forename: Alina
authors.initials: A
authors.lastname: Popescu
authors.affiliation: Department of Gastroneterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy Timisoara, Romania.
authors.forename: Ioan
authors.initials: I
authors.lastname: Sporea
authors.affiliation: Department of Gastroneterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy Timisoara, Romania.
authors.forename: Roxana
authors.initials: R
authors.lastname: Şirli
authors.affiliation: Department of Gastroneterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy Timisoara, Romania.
authors.forename: Mirela
authors.initials: M
authors.lastname: Dănilă
authors.affiliation: Department of Gastroneterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy Timisoara, Romania.
authors.forename: Ruxandra
authors.initials: R
authors.lastname: Mare
authors.affiliation: Department of Gastroneterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy Timisoara, Romania.
authors.forename: Oana
authors.initials: O
authors.lastname: Grădinaru Taşcău
authors.affiliation: Department of Gastroneterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy Timisoara, Romania.
authors.forename: Tudor
authors.initials: T
authors.lastname: Moga
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008100:Liver Abscess / Q000000981:diagnostic imaging*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010743:Phospholipids; D015203:Reproducibility of Results; D018570:Risk Assessment; D012307:Risk Factors; D012680:Sensitivity and Specificity; D013459:Sulfur Hexafluoride; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods*; D055815:Young Adult
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride