title: Alternatives to Antibiotics to Prevent Necrotic Enteritis in Broiler Chickens: A Microbiologist's Perspective.
abstract: Since the 2006 European ban on the use of antibiotics as growth promoters in animal feed, numerous studies have been published describing alternative strategies to prevent diseases in animals. A particular focus has been on prevention of necrotic enteritis in poultry caused by Clostridium perfringens by the use of microbes or microbe-derived products. Microbes produce a plethora of molecules with antimicrobial properties and they can also have beneficial effects through interactions with their host. Here we review recent developments in novel preventive treatments against C. perfringens-induced necrotic enteritis in broiler chickens that employ yeasts, bacteria and bacteriophages or secondary metabolites and other microbial products in disease control.
authors.affiliation: Université Lille, INRA, ISA, Université Artois, Université Littoral Côte d'Opale, Institut Charles Viollette Lille, France.
authors.forename: Delphine L
authors.initials: DL
authors.lastname: Caly
authors.affiliation: Société Industrielle Lesaffre, Phileo Lesaffre Animal Care Marcq-en-Baroeul, France.
authors.forename: Romain
authors.initials: R
authors.lastname: D'Inca
authors.affiliation: Société Industrielle Lesaffre, Phileo Lesaffre Animal Care Marcq-en-Baroeul, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Auclair
authors.affiliation: Université Lille, INRA, ISA, Université Artois, Université Littoral Côte d'Opale, Institut Charles Viollette Lille, France.
authors.forename: Djamel
authors.initials: D
authors.lastname: Drider
keywords: Clostridium perfringens; antimicrobials; bacteriocin; broiler chicken; competitive exclusion; necrotic enteritis; probiotic