title: Penile cancer: about ten cases at the University Hospital of Rabat, review of the literature.
abstract: The aim of our study was to report the status of penile cancer sites in the urology department at the University Hospital of Rabat and evaluate long-term results of surgical treatment of this cancer.
  
  
  METHODS
  Between 1989 and 2015, 10 patients were treated for penile cancer. 10 cases were retrospectively reviewed and the following data were recorded: mode of revelation, seat, staging, TNM stage, treatment, evolution and survival. The mean age of patients was 58,1 years (48-81 years). All patients had squamous cell carcinoma of the penis. Six patients had a partial amputation of the penis, and three patients underwent total amputation. The median size of the lesion was 4.25 cm (1.5-8 cm). All tumors had a distal seat (gland- Furrow balanopreputial), 8 were localized and non-invasive (PT1 - PT2) and 2 had infiltrated the urethra (PT3). Four patients had lymph node localization. A single bilateral lymphadenectomy was performed and was positive only on one side, with a node <3 cm and no extracapsular extension. Two patients were referred for chemotherapy, a neoadjuvant referred to basic (Bleomycin - Methotrexate, Cisplatin) the other in a palliative goal. Median follow-up was 42 months (6 -72mois). Four patients died, one of which was presented immediately with metastatic mode. Six patients were alive at last node or local recurrence negative. Cancer of the penis seems rare in Morocco. His oncologic and functional outcomes (sexual and urinary) depend on the precocity of the treatment. The surgery of lymph node resection with lymphadenectomy remains the reference treatment.
authors.affiliation: Urology B, Ibn Sina University Hospital, Rabat, Morocco.
authors.forename: Amine
authors.initials: A
authors.lastname: Slaoui
authors.affiliation: Urology B, Ibn Sina University Hospital, Rabat, Morocco.
authors.forename: Youness
authors.initials: Y
authors.lastname: Jabbour
authors.affiliation: Urology B, Ibn Sina University Hospital, Rabat, Morocco.
authors.forename: Anouar
authors.initials: A
authors.lastname: El Ghazoui
authors.affiliation: Urology B, Ibn Sina University Hospital, Rabat, Morocco.
authors.forename: Tarik
authors.initials: T
authors.lastname: Karmouni
authors.affiliation: Urology B, Ibn Sina University Hospital, Rabat, Morocco.
authors.forename: Khalid
authors.initials: K
authors.lastname: Elkhader
authors.affiliation: Urology B, Ibn Sina University Hospital, Rabat, Morocco.
authors.forename: Abdelatif
authors.initials: A
authors.lastname: Koutani
authors.affiliation: Urology B, Ibn Sina University Hospital, Rabat, Morocco.
authors.forename: Ahmed Ibn
authors.initials: AI
authors.lastname: Attaya
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009018:Morocco / Q000453:epidemiology; D020360:Neoadjuvant Therapy / Q000379:methods; D010412:Penile Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies
chemical_list: D000970:Antineoplastic Agents
keywords: Partial penectomy; Penile Cancer; lymphadenectomy; total penectomy