title: The challenges in producing high-quality clinical evidence.
authors.affiliation: Department of Anesthesia, University Health Network, University of Toronto, Toronto, ON, Canada. scott.beattie@uhn.ca.
authors.forename: W Scott
authors.initials: WS
authors.lastname: Beattie
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011785:Quality Assurance, Health Care; D016032:Randomized Controlled Trials as Topic / Q000592:standards*