title: Recording of Neonatal Seizures in Birth Certificates, Maternal Interviews, and Hospital Discharge Abstracts in a Cerebral Palsy Case-Control Study in Michigan.
abstract: We evaluated the recording of neonatal seizures in birth certificates, hospital discharge abstracts, and maternal interviews in 372 children, 198 of them with cerebral palsy, born in Michigan hospitals from 1993 to 2010. In birth certificates, we examined checkbox items "seizures" or "seizure or serious neurologic dysfunction"; in hospital discharge abstracts ICD-9-CM codes 779.0, 345.X, and 780.3; and in maternal interviews a history of seizures or convulsions on day 1 of life recalled 2-16 years later. In 27 neonates, 38 neonatal seizures were recorded in 1 or more sources, 17 in discharge abstracts, 20 in maternal interviews, but just 1 on a birth certificate. The kappa coefficient (κ) between interviews and discharge abstracts was moderate (κ = 0.55), and substantial (κ = 0.63) if mothers noted use of antiepileptics. Agreement was higher (κ = 0.71 vs κ = 0.29) in term births than in preterm births. Birth certificates significantly underreported neonatal seizures.
authors.affiliation: Department of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI, USA Departments of Obstetrics and Gynecology and Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA liqi@musc.edu youliqing08@gmail.com.
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
authors.affiliation: Department of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI, USA.
authors.forename: Madeleine
authors.initials: M
authors.lastname: Lenski
authors.affiliation: Michigan Department of Community Health, Division for Vital Records and Health Statistics, Lansing, MI, USA.
authors.forename: Glenn
authors.initials: G
authors.lastname: Copeland
authors.affiliation: Department of Pediatrics, Division of Pediatric Neurology, Medical University of South Carolina, Charleston, SC, USA.
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Kinsman
authors.affiliation: Department of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Francis
authors.affiliation: University of South Florida, College of Public Health, Department of Community and Family Health, Tampa, FL, USA.
authors.forename: Russell S
authors.initials: RS
authors.lastname: Kirby
authors.affiliation: Department of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI, USA Department of Pediatrics and Human Development, Michigan State University, East Lansing, MI, USA.
authors.forename: Nigel
authors.initials: N
authors.lastname: Paneth
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D001719:Birth Certificates; D016022:Case-Control Studies; D002547:Cerebral Palsy / Q000453:epidemiology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D004282:Documentation; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007407:Interviews as Topic; D008297:Male; D008824:Michigan; D009035:Mothers; D010351:Patient Discharge; D012640:Seizures / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology
chemical_list: D000927:Anticonvulsants
keywords: United States Standard Certificate of Live Birth; cerebral palsy; hospital discharge abstracts; neonatal seizures