title: Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy to Treat Morbid Obesity-Related Comorbidities: a Systematic Review and Meta-analysis.
abstract: Our aim was to compare laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) for treating morbid obesity and its related comorbidities. An electronic literature search was performed from inception to May 2015 and a total of 18,455 patients, enrolled in 62 recent studies, were included in this meta-analysis. Patients receiving LRYGB had a significantly higher percentage of excess weight loss and better resolution of hypertension, dyslipidemia, gastroesophageal reflux disease, and arthritis compared with those receiving LSG. LRYGB and LSG showed similar effects on type 2 diabetes mellitus and sleep apnea.
authors.affiliation: Department of Gastrointestinal Surgery, The First People's Hospital of Xiaoshan, No. 199 Shixinnan Road, Hangzhou, Zhejiang Province, 311200, China. ljfldd611@163.com.
authors.forename: Jianfang
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Gastrointestinal Surgery, The First People's Hospital of Xiaoshan, No. 199 Shixinnan Road, Hangzhou, Zhejiang Province, 311200, China.
authors.forename: Dandan
authors.initials: D
authors.lastname: Lai
authors.affiliation: Department of Gastrointestinal Surgery, The First People's Hospital of Xiaoshan, No. 199 Shixinnan Road, Hangzhou, Zhejiang Province, 311200, China.
authors.forename: Dongping
authors.initials: D
authors.lastname: Wu
mesh_terms: D001168:Arthritis / Q000209:etiology; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology; D050171:Dyslipidemias / Q000209:etiology; D005743:Gastrectomy / Q000379:methods*; D015390:Gastric Bypass; D005764:Gastroesophageal Reflux / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000209:etiology; D010535:Laparoscopy; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*; D012891:Sleep Apnea Syndromes / Q000209:etiology; D015431:Weight Loss
keywords: Meta-analysis; Obesity; Review; Roux-en-Y gastric bypass; Sleeve gastrectomy