title: Secondary cell walls: biosynthesis and manipulation.
abstract: Secondary cell walls (SCWs) are produced by specialized plant cell types, and are particularly important in those cells providing mechanical support or involved in water transport. As the main constituent of plant biomass, secondary cell walls are central to attempts to generate second-generation biofuels. Partly as a consequence of this renewed economic importance, excellent progress has been made in understanding how cell wall components are synthesized. SCWs are largely composed of three main polymers: cellulose, hemicellulose, and lignin. In this review, we will attempt to highlight the most recent progress in understanding the biosynthetic pathways for secondary cell wall components, how these pathways are regulated, and how this knowledge may be exploited to improve cell wall properties that facilitate breakdown without compromising plant growth and productivity. While knowledge of individual components in the pathway has improved dramatically, how they function together to make the final polymers and how these individual polymers are incorporated into the wall remain less well understood.
authors.affiliation: University of Manchester, The Micheal Smith Building, Oxford Road, Manchester M13 9PT, UK.
authors.forename: Manoj
authors.initials: M
authors.lastname: Kumar
authors.affiliation: University of Manchester, The Micheal Smith Building, Oxford Road, Manchester M13 9PT, UK.
authors.forename: Liam
authors.initials: L
authors.lastname: Campbell
authors.affiliation: University of Manchester, The Micheal Smith Building, Oxford Road, Manchester M13 9PT, UK simon.turner@manchester.ac.uk.
authors.forename: Simon
authors.initials: S
authors.lastname: Turner
mesh_terms: D002473:Cell Wall / Q000378:metabolism*; D008031:Lignin / Q000378:metabolism; D059828:Plant Cells / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*; D011134:Polysaccharides / Q000378:metabolism
chemical_list: D011134:Polysaccharides; C007916:hemicellulose; D008031:Lignin
keywords: Biofuels; SCW; cellulose; lignin; lignin engineering; regulation; xylan; xylan engineering.