title: Prevalence and risk factors of retinopathy in patients with or without metabolic syndrome: a population-based study in Shenyang.
abstract: OBJECTIVE
  To investigate the relationship between metabolic syndrome (MS) and the prevalence of retinopathy.
  
  
  METHODS
  A cross-sectional study was carried out from August 2013 to September 2014 in Fengyutan Sub-District.
  
  
  METHODS
  A total of 1163 eligible participants attended. All the participants were subjected to stereo fundus photography to detect retinopathy. The discrepancy of prevalence of retinopathy in different participants was described.
  
  
  RESULTS
  The prevalence of retinopathy was 9.64% in patients with MS and 3.91% in patients without MS. A higher prevalence of retinopathy with proliferative diabetic retinopathy was found in patients with MS. In multiple logistic regression analysis, independent risk factors for any retinopathy in patients with MS were longer diabetes duration (OR 1.07; 95% CI 1.04 to 1.10, per year increase), higher systolic blood pressure (SBP) (OR 1.16; 95% CI 1.09 to 1.29, per 10 mm Hg increase), higher diastolic blood pressure (DBP) (OR 1.24; 95% CI 1.12 to 1.35, per 10 mm Hg increase), higher fasting plasma glucose (OR 1.07; 95% CI 1.02 to 1.11, per 10 mg/dL increase), higher 2 h postprandial plasma glucose (OR 1.17; 95% CI 1.12 to 1.21, per 10 mg/dL increase), and higher haemoglobin A1c (HbA1c) (OR 1.23; 95% CI 1.13 to 1.34, per % increase). Similar independent risk factors, except for DBP, were found for any retinopathy in patients without MS.
  
  
  CONCLUSIONS
  The presence of MS components, hyperglycaemia (fasting glucose and HbA1c) and hypertension (SBP and DBP), are significantly associated with the prevalence of retinopathy.
authors.affiliation: Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, China.
authors.forename: Song
authors.initials: S
authors.lastname: Yue
authors.affiliation: Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, China.
authors.forename: Jingyang
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, China.
authors.forename: Jiahua
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Health Center, Fengyutan Sub-District, Shenyang, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Lian
authors.affiliation: Key Laboratory of Endocrine Diseases in Liaoning Province, The First Affiliated Hospital of China Medical University, Shenyang, China.
authors.forename: Weiping
authors.initials: W
authors.lastname: Teng
authors.affiliation: Department of Epidemiology, School of Public Health, China Medical University, Shenyang, China.
authors.forename: Desheng
authors.initials: D
authors.lastname: Huang
authors.affiliation: Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, China Key Laboratory of Endocrine Diseases in Liaoning Province, The First Affiliated Hospital of China Medical University, Shenyang, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D003930:Diabetic Retinopathy / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D012164:Retinal Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors
keywords: DIABETES & ENDOCRINOLOGY; EPIDEMIOLOGY