title: Phenytoin-induced acute hypersensitivity pneumonitis.
abstract: Lungs are target organs for toxic effects of various drugs due to many reasons. Diphenylhydantoin (DPH) is reported to have many extrapulmonary side effects. We are presenting a case of acute hypersensitivity pneumonitis (HP) secondary to DPH, presenting with respiratory failure. Acute HP with respiratory failure is an uncommon drug side effect of the DPH therapy and is a diagnosis of exclusion. It requires detailed workup and exclusion of other causes along with evidence of improvement in the patient's condition after withholding DPH.
authors.affiliation: Metro Centre for Respiratory Diseases, Metro Hospitals and Heart Institute, Noida, Uttar Pradesh, India.
authors.forename: Pallavi
authors.initials: P
authors.lastname: Periwal
authors.affiliation: Metro Centre for Respiratory Diseases, Metro Hospitals and Heart Institute, Noida, Uttar Pradesh, India.
authors.forename: Sharad
authors.initials: S
authors.lastname: Joshi
authors.affiliation: Metro Centre for Respiratory Diseases, Metro Hospitals and Heart Institute, Noida, Uttar Pradesh, India.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Gothi
authors.affiliation: Metro Centre for Respiratory Diseases, Metro Hospitals and Heart Institute, Noida, Uttar Pradesh, India.
authors.forename: Deepak
authors.initials: D
authors.lastname: Talwar
keywords: Diphenylhydantoin; drug-induced hypersensitivity pneumonitis; hypersensitivity pneumonitis