title: Autofluorescence imaging of basal cell carcinoma by smartphone RGB camera.
abstract: The feasibility of smartphones for in vivo skin autofluorescence imaging has been investigated. Filtered autofluorescence images from the same tissue area were periodically captured by a smartphone RGB camera with subsequent detection of fluorescence intensity decreasing at each image pixel for further imaging the planar distribution of those values. The proposed methodology was tested clinically with 13 basal cell carcinoma and 1 atypical nevus. Several clinical cases and potential future applications of the smartphone-based technique are discussed.
authors.affiliation: University of Latvia, Institute of Atomic Physics and Spectroscopy, Biophotonics Laboratory, Raina Boulevard 19, Riga LV-1586, Latvia.
authors.forename: Alexey
authors.initials: A
authors.lastname: Lihachev
authors.affiliation: Riga East University Hospital, Oncology Centre of Latvia, Hipokrata Street 4, Riga LV-1079, Latvia.
authors.forename: Alexander
authors.initials: A
authors.lastname: Derjabo
authors.affiliation: University of Latvia, Institute of Atomic Physics and Spectroscopy, Biophotonics Laboratory, Raina Boulevard 19, Riga LV-1586, Latvia.
authors.forename: Inesa
authors.initials: I
authors.lastname: Ferulova
authors.affiliation: University of Latvia, Institute of Atomic Physics and Spectroscopy, Biophotonics Laboratory, Raina Boulevard 19, Riga LV-1586, Latvia.
authors.forename: Marta
authors.initials: M
authors.lastname: Lange
authors.affiliation: University of Latvia, Institute of Atomic Physics and Spectroscopy, Biophotonics Laboratory, Raina Boulevard 19, Riga LV-1586, Latvia.
authors.forename: Ilze
authors.initials: I
authors.lastname: Lihacova
authors.affiliation: University of Latvia, Institute of Atomic Physics and Spectroscopy, Biophotonics Laboratory, Raina Boulevard 19, Riga LV-1586, Latvia.
authors.forename: Janis
authors.initials: J
authors.lastname: Spigulis
mesh_terms: D002280:Basal Cell Carcinoma / Q000175:diagnosis*; D003094:Collagen / Q000737:chemistry; D046169:Dermoscopy; D005453:Fluorescence; D006801:Humans; D008027:Light; D008856:Microscopy, Fluorescence / Q000379:methods*; D009243:NAD / Q000737:chemistry; D009506:Nevus / Q000473:pathology; D038761:Photobleaching; D011166:Porphyrins / Q000737:chemistry; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis*; D000068997:Smartphone
chemical_list: D011166:Porphyrins; D009243:NAD; D003094:Collagen