title: New eudesmane-type sesquiterpenoids from the root bark of Pseudolarix kaempferi.
abstract: The phytochemical investigation of the root bark of Pseudolarix kaempferi yielded eight eudesmane-type sesquiterpenoids, including three new ones, 1α-hydroxyl-4(14)-en-β-dihydroagarafuran (1), 1α, 2α-diacetoxy-8β-isobutanoyloxy-9α-benzoyl oxy-15-β-(β-furancarbonyloxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (7), and 1α-acetoxy-2 α-furancarbonyloxy-8β-isobutanoyloxy-9α-benzoyloxy-15β-(β-acetoxy)-4β, 6β-dihydroxy-β-dihydroagarofuran (8). Herein the new compounds 7 and 8 were reported as a mixture. The molecular structures of the isolated compounds were elucidated on the basis of extensive spectroscopic analysis, including UV, IR, NMR, and MS, and comparison with the literature data.
authors.affiliation: a Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province , Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS) , Lanzhou 730000 , China.|b College of Chemistry and Chemical Engineering , University of Chinese Academy of Sciences , Beijing 100049 , China.
authors.forename: Hai-Long
authors.initials: HL
authors.lastname: Jiang
authors.affiliation: a Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province , Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS) , Lanzhou 730000 , China.
authors.forename: Wei
authors.initials: W
authors.lastname: Ha
authors.affiliation: a Key Laboratory of Chemistry of Northwestern Plant Resources of CAS and Key Laboratory for Natural Medicine of Gansu Province , Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS) , Lanzhou 730000 , China.
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Shi
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D028201:Pinaceae / Q000737:chemistry*; D024301:Plant Bark / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes; D045787:Sesquiterpenes, Eudesmane; C079978:dihydroagarofuran; C015872:eudesmane
keywords: Pinaceae; Pseudolarix kaempferi; eudesmane; sesquiterpenoid