title: Malignant transformation of diffuse infiltrating glial neoplasm after prolonged stable period initially discovered with hypothalamic hamartoma.
abstract: We present a case of malignant transformation of diffuse infiltrating glial neoplasm after a prolonged stable period on magnetic resonance imaging (MRI) and spectroscopy (MRS) initially discovered with a hypothalamic hamartoma. Although MRI and MRS suggest the possibility of malignant transformation in future, they cannot precisely predict the timing of rapid growth.
authors.affiliation: Department of Advanced Medical Imaging, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan. Electronic address: fumiaki@staff.kanazawa-u.ac.jp.
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Ueda
authors.affiliation: Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Aburano
authors.affiliation: Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Yoshie
authors.affiliation: Department of Advanced Medical Imaging, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Matsui
authors.affiliation: Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan.
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Gabata
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology*; D002648:Child; D005910:Glioma / Q000473:pathology*; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D007027:Hypothalamic Diseases / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male
keywords: Diffuse astrocytoma; Gliomatosis cerebri; Hypothalamic hamartoma; Magnetic resonance imaging; Magnetic resonance spectroscopy