title: Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment.
abstract: Current cell sheet-based blood vessels lack biomimetic structure and require excessively long culture times that may compromise smooth muscle cell phenotype. We modified a commercially available product for uniaxial cell sheet conditioning with thermoresponsive copolymers. Thus, culture of detachable conditioned cell sheets is shortened while retaining structural integrity and contractility.
authors.affiliation: Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
authors.forename: E L
authors.initials: EL
authors.lastname: Lee
authors.affiliation: Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
authors.forename: H H
authors.initials: HH
authors.lastname: Bendre
authors.affiliation: Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
authors.forename: A
authors.initials: A
authors.lastname: Kalmykov
authors.affiliation: Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA ; Department of Materials Science and Engineering, Boston University, Boston, MA 02215, USA.
authors.forename: J Y
authors.initials: JY
authors.lastname: Wong