title: Analysis of 24 Y-STR haplotype data in a Chinese Han population from Guangdong Province.
abstract: In this study, we investigated the genetic polymorphisms of 24 Y-chromosomal short tandem repeat (Y-STR) loci in 885 unrelated Chinese Han male individuals from Guangdong Province, using a domestic AGCU Y24 STR kit. A total of 878 different haplotypes were observed at the 24 Y-STR loci; among them, 871 haplotypes were unique and 7 haplotypes occurred twice. The overall haplotype diversity was 0.99998 and the discrimination capacity was 99.2%. The gene diversity values ranged from 0.4354 at DYS438 to 0.9606 at DYS385a/b. Population relationships between the Guangdong Han population and seven other published Chinese populations were evaluated by Rst values and visualized in a two multi-dimensional scaling plot. The results showed the 24 Y-STR loci are highly polymorphic in Guangdong Han population and of great value in forensic application.
authors.affiliation: Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Guangdong Provincial Key Laboratory of Forensic Genetics, Guangzhou, 510030, People's Republic of China.|Guangzhou Institute for Criminal Science and Technology, Guangzhou, 510030, People's Republic of China.
authors.forename: Chao
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
authors.forename: Chu-chu
authors.initials: CC
authors.lastname: Zhang
authors.affiliation: Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
authors.forename: Ran
authors.initials: R
authors.lastname: Li
authors.affiliation: Guangdong Provincial Key Laboratory of Forensic Genetics, Guangzhou, 510030, People's Republic of China.|Guangzhou Institute for Criminal Science and Technology, Guangzhou, 510030, People's Republic of China.
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
authors.forename: Xue-ling
authors.initials: XL
authors.lastname: Ou
authors.affiliation: Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China.
authors.forename: Hai-xia
authors.initials: HX
authors.lastname: Li
authors.affiliation: Department of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, People's Republic of China. sunhy@mail.sysu.edu.cn.
authors.forename: Hong-yu
authors.initials: HY
authors.lastname: Sun
mesh_terms: D044466:Asian People / Q000235:genetics; D002681:China / Q000208:ethnology; D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting; D005006:Ethnicity / Q000235:genetics*; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
keywords: AGCU Y24 STR; Guangdong Han population; Haplotype