title: [Coagulation factor XIII – Pathophysiology, clinic and therapy of factor XIII deficiency].
abstract: The complex activity of the transglutaminase factor XIII (FXIII) comprises central functions in secondary hemostasis. Congenital or acquired FXIII deficiencies may be associated with habitual abortions, impaired wound healing, coagulopathy and fatal hemorrhage. The present review describes physiological functions of FXIII, as well as pathophysiology, diagnostic and therapeutic options of FXIII deficiencies.
authors.forename: Christian Friedrich
authors.initials: CF
authors.lastname: Weber
authors.forename: Elisabeth Hannah
authors.initials: EH
authors.lastname: Adam
authors.forename: Andreas
authors.initials: A
authors.lastname: Pape
authors.forename: Marina
authors.initials: M
authors.lastname: Jöst
authors.forename: Patrick
authors.initials: P
authors.lastname: Meybohm
authors.forename: Katja
authors.initials: K
authors.lastname: Schmitz
authors.forename: Kai
authors.initials: K
authors.lastname: Zacharowski
authors.forename: Martin
authors.initials: M
authors.lastname: Hermann
authors.forename: Dietmar
authors.initials: D
authors.lastname: Fries
mesh_terms: D001778:Blood Coagulation Disorders / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D001780:Blood Coagulation Tests / Q000379:methods; D001803:Blood Transfusion; D005177:Factor XIII Deficiency / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D005820:Genetic Testing / Q000379:methods; D006470:Hemorrhage / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage
chemical_list: D007166:Immunosuppressive Agents