title: A Comparison of Mortality Prognostic Scores in Ischemic Stroke Patients.
abstract: OBJECTIVE
  Our objective is to compare the predictive accuracy of 4 recently established stroke mortality scores in the Chinese population, including the Get With The Guidelines-Stroke risk score, the iScore prediction rule for 30-day mortality, the iScore prediction rule for 1-year mortality, and the PLAN score.
  
  
  METHODS
  We analyzed data from 9698 hospitalized patients with acute ischemic stroke in the China National Stroke Registry (September 2007-August 2008). Outcome measures were in-hospital mortality, 30-day mortality, and 1-year mortality. To evaluate the performance of each model, we calculated the area under the receiver operating characteristic curve. The areas under the curve (AUCs) were compared using the z-test.
  
  
  RESULTS
  Among 9698 patients, the mean age was 65.5 years and 38.6% were female. Overall in-hospital mortality, 30-day mortality, and 1-year mortality were 3.0%, 5.9%, and 14.6%, respectively. The AUC values of 4 scores for each outcome were all more than .75. The z-test did not show significant difference among the AUC values of these 4 scores. For patients who received thrombolysis therapy, these 4 scores had apparent reductions in the AUC values.
  
  
  CONCLUSIONS
  We could confirm the predictive value of all these 4 scores for short-term and long-term mortalities in Chinese IS patients. However, these 4 scores need to be interpreted with caution in the patients who received thrombolysis therapy.
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Xu
authors.affiliation: Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Henan, China.
authors.forename: Yongli
authors.initials: Y
authors.lastname: Tao
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors.forename: Xuewei
authors.initials: X
authors.lastname: Xie
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors.forename: Gaifen
authors.initials: G
authors.lastname: Liu
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors.forename: Anxin
authors.initials: A
authors.lastname: Wang
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. Electronic address: yilong528@aliyun.com.
authors.forename: Yilong
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000401:mortality*; D002681:China; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D012042:Registries; D012720:Severity of Illness Index; D020521:Stroke / Q000401:mortality*; D055815:Young Adult
keywords: Ischemic stroke; mortality; prognosis; risk factor