title: Prevalence of dengue viral and malaria parasitic co-infections in an epidemic district, Angul of Odisha, India: An eco-epidemiological and cross-sectional study for the prospective aspects of public health.
abstract: The co-existence of dengue and malaria infection in an individual and the primary and secondary dengue infection during co-infection were assessed. Over 1 year, 1980 blood samples were collected from suspected cases of dengue fever and analyzed by rapid diagnostic test (RDT), enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) methods to detect dengue infection. RDT and microscopic methods were used to detect malaria. Of the 1980 samples, only 22 (3.0%) cases were identified as dengue-malaria co-infection cases, out of which 13 were male and 9 were female. The highest number of confirmed cases were found during the hot and humid months of September and October (7 cases, 31.8%) and within the over 15 years age group. Of the cases of co-infection, dengue primary infection (21 cases, 95.5%) was significantly more common than dengue secondary infection (1 case, 4.5%) among all of the age groups. There were 12 cases of Plasmodium falciparum and 10 cases of Plasmodium vivax infection among malarial cases. A high prevalence of concurrence of dengue and malaria infection was recorded in this ecosystem. In light of the severity of co-infection and overlapping symptoms, a multidimensional diagnostic approach is suggested.
authors.affiliation: Department of Biotechnology, Sai Nath University, Ranchi, Jharkhand, India. Electronic address: raomrajeshkumar@gmail.com.
authors.forename: M Rajesh Kumar
authors.initials: MR
authors.lastname: Rao
authors.affiliation: Central Research Laboratory, Institute of Medical Sciences & Sum Hospital, Siksha 'O' Anusandhan University, K-8, Kalinga Nagar, Bhubaneswar 751003, Odisha, India.
authors.forename: Rabindra N
authors.initials: RN
authors.lastname: Padhy
authors.affiliation: National Institute of Malaria Research, Field Unit, ITKI, Ranchi, Jharkhand, India.
authors.forename: Manoj K
authors.initials: MK
authors.lastname: Das
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002846:Chromatography, Affinity; D060085:Coinfection / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D003715:Dengue / Q000150:complications* / Q000453:epidemiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008288:Malaria / Q000150:complications* / Q000453:epidemiology*; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000302:isolation & purification; D010966:Plasmodium vivax / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D015995:Prevalence; D012621:Seasons; D055815:Young Adult
keywords: Co-infection; Dengue; Malaria; Odisha; Surveillance