title: Comparison of National Operative Mortality in Gastroenterological Surgery Using Web-based Prospective Data Entry Systems.
abstract: International collaboration is important in healthcare quality evaluation; however, few international comparisons of general surgery outcomes have been accomplished. Furthermore, predictive model application for risk stratification has not been internationally evaluated. The National Clinical Database (NCD) in Japan was developed in collaboration with the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP), with a goal of creating a standardized surgery database for quality improvement. The study aimed to compare the consistency and impact of risk factors of 3 major gastroenterological surgical procedures in Japan and the United States (US) using web-based prospective data entry systems: right hemicolectomy (RH), low anterior resection (LAR), and pancreaticoduodenectomy (PD).Data from NCD and ACS-NSQIP, collected over 2 years, were examined. Logistic regression models were used for predicting 30-day mortality for both countries. Models were exchanged and evaluated to determine whether the models built for one population were accurate for the other population.We obtained data for 113,980 patients; 50,501 (Japan: 34,638; US: 15,863), 42,770 (Japan: 35,445; US: 7325), and 20,709 (Japan: 15,527; US: 5182) underwent RH, LAR, and, PD, respectively. Thirty-day mortality rates for RH were 0.76% (Japan) and 1.88% (US); rates for LAR were 0.43% versus 1.08%; and rates for PD were 1.35% versus 2.57%. Patient background, comorbidities, and practice style were different between Japan and the US. In the models, the odds ratio for each variable was similar between NCD and ACS-NSQIP. Local risk models could predict mortality using local data, but could not accurately predict mortality using data from other countries.We demonstrated the feasibility and efficacy of the international collaborative research between Japan and the US, but found that local risk models remain essential for quality improvement.
authors.affiliation: From the Member of Database Committee of Japanese Society of Gastroenterological Surgery (TA, GW); Division of Research and Optimal Patient Care, American College of Surgeons, Chicago, IL (JLP, CYK, MEC, LZ); National Clinical Database, Tokyo, Japan (HM, MG, NH, HK); and Japanese Society of Gastroenterological Surgery, Tokyo, Japan (HM, MG, HK, KS, MM).
authors.forename: Takayuki
authors.initials: T
authors.lastname: Anazawa
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Paruch
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Miyata
authors.forename: Mitsukazu
authors.initials: M
authors.lastname: Gotoh
authors.forename: Clifford Y
authors.initials: CY
authors.lastname: Ko
authors.forename: Mark E
authors.initials: ME
authors.lastname: Cohen
authors.forename: Norimichi
authors.initials: N
authors.lastname: Hirahara
authors.forename: Lynn
authors.initials: L
authors.lastname: Zhou
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Konno
authors.forename: Go
authors.initials: G
authors.lastname: Wakabayashi
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sugihara
authors.forename: Masaki
authors.initials: M
authors.lastname: Mori
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003082:Colectomy / Q000401:mortality; D015897:Comorbidity; D016208:Databases, Factual / Q000706:statistics & numerical data*; D013505:Digestive System Surgical Procedures / Q000401:mortality*; D005260:Female; D006801:Humans; D020407:Internet; D007564:Japan / Q000453:epidemiology; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D016577:Pancreaticoduodenectomy / Q000401:mortality; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D058996:Quality Improvement / Q000458:organization & administration*; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D014481:United States / Q000453:epidemiology