title: Predictive Factors of Ventilator Dependency after Colon and Rectal Surgery.
abstract: There is limited data analyzing ventilator dependency by operative diagnoses and types of the procedures performed in colorectal surgery. We sought to identify predictive factors of ventilator dependency in colorectal surgery and investigate complication rates across various colorectal procedures. The National Surgical Quality Improvement Program database was used to examine the clinical data of patients with ventilator dependency for more than 48 hours after colorectal resection during 2005-2013. Multivariate regression analysis was performed to identify predictors of ventilator dependency. A total of 219,716 patients who underwent colorectal resection were identified. The rate of ventilator dependency was 3.9 per cent. The rate varied significantly based on patient diagnosis; with the highest rate seen in patients with acute mesenteric ischemia (25.9%). The highest risk of ventilator dependency according to the patients indication of surgery, type of the procedure, and preoperative factors exist in lower gastrointestinal bleeding [adjusted odds ratio (AOR): 77.44, P < 0.01], total colectomy (AOR: 1.58, P = 0.04), and American Society of Anesthesiologists classification of three or greater (AOR: 2.52, P < 0.01). Also, serum albumin level (AOR: 0.67, P < 0.01) seems to be associated with ventilator dependency. The overall rate of ventilator dependency is 3.9 per cent in colorectal surgery. However, depending on the indication for surgery, rates can be as high as 25.9 per cent. American Society of Anesthesiologist score can predict the risk of postoperative ventilator dependency in patients undergoing colorectal surgery. Serum albumin level is reversely associated with postoperative ventilator dependency.
authors.affiliation: Department of Surgery, School of Medicine, University of California, Irvine, Orange, California, USA.
authors.forename: Zhobin
authors.initials: Z
authors.lastname: Moghadamyeghaneh
authors.forename: Grace
authors.initials: G
authors.lastname: Hwang
authors.forename: Mark H
authors.initials: MH
authors.lastname: Hanna
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Carmichael
authors.forename: Steven D
authors.initials: SD
authors.lastname: Mills
authors.forename: Alessio
authors.initials: A
authors.lastname: Pigazzi
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Stamos
mesh_terms: D003106:Colon / Q000601:surgery*; D003107:Colorectal Surgery; D005260:Female; D005544:Forecasting; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012007:Rectum / Q000601:surgery*; D012044:Regression Analysis; D015300:Ventilator Weaning