title: Factors for short-term outcomes in patients with a minor stroke: results from China National Stroke Registry.
abstract: BACKGROUND
  Stroke recurrence and disability in patients with a minor stroke is one of the most depressing medical situations. In this study, we aimed to identify which factors were associated with adverse outcomes of a minor stroke.
  
  
  METHODS
  The China National Stroke Registry (CNSR) is a nationwide prospective registry for patients presented to hospitals with acute cerebrovascular events between September 2007 and August 2008. The 3-month follow-up was completed in 4669 patients with a minor stroke defined as the initial neurological severity lower than 4 in the National Institutes of Health Stroke Scale (NIHSS). Multivariate model was used to determine the association between risk factors and clinical outcomes.
  
  
  RESULTS
  Of 4669 patients with a minor stroke during 3-month follow-up, 459 (9.8 %) patients experienced recurrent stroke, 679 (14.5 %) had stroke disability and 168 (3.6 %) died. Multivariate model identified hypertension, diabetes mellitus, atrial fibrillation, coronary heart disease and previous stroke as independent predictors for the recurrent stroke. Age, diabetes mellitus, atrial fibrillation, previous stroke and time from onset to admission < 24 h were independent predictors for stroke disability. The independent predictors for the all-caused death were age, atrial fibrillation, and coronary heart disease.
  
  
  CONCLUSIONS
  The short-term risk of poor clinical outcome in Chinese patients with a minor stroke was substantial. Therefore, patients with a minor stroke should be given expeditious assessment and urgent aggressive intervention.
authors.affiliation: Graduate School, North China University of Science and Technology, Tangshan, China. 15133916062@163.com.
authors.forename: Lingyun
authors.initials: L
authors.lastname: Wu
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. anxin0907@163.com.|China National Clinical Research Center for Neurological Diseases, Beijing, China. anxin0907@163.com.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. anxin0907@163.com.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. anxin0907@163.com.|Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China. anxin0907@163.com.
authors.forename: Anxin
authors.initials: A
authors.lastname: Wang
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. xianweiw2005@gmail.com.|China National Clinical Research Center for Neurological Diseases, Beijing, China. xianweiw2005@gmail.com.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. xianweiw2005@gmail.com.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. xianweiw2005@gmail.com.
authors.forename: Xianwei
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. zxq@vip.163.com.|China National Clinical Research Center for Neurological Diseases, Beijing, China. zxq@vip.163.com.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. zxq@vip.163.com.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. zxq@vip.163.com.
authors.forename: Xingquan
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. snowsen@126.com.|China National Clinical Research Center for Neurological Diseases, Beijing, China. snowsen@126.com.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. snowsen@126.com.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. snowsen@126.com.
authors.forename: Chunxue
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. lipingsister@gmail.com.|China National Clinical Research Center for Neurological Diseases, Beijing, China. lipingsister@gmail.com.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. lipingsister@gmail.com.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. lipingsister@gmail.com.
authors.forename: Liping
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. zhgdoc@163.com.|China National Clinical Research Center for Neurological Diseases, Beijing, China. zhgdoc@163.com.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. zhgdoc@163.com.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. zhgdoc@163.com.
authors.forename: Huaguang
authors.initials: H
authors.lastname: Zheng
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. yongjunwang1962@gmail.com.|China National Clinical Research Center for Neurological Diseases, Beijing, China. yongjunwang1962@gmail.com.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. yongjunwang1962@gmail.com.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. yongjunwang1962@gmail.com.
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Neurology, Tangshan Gongren Hospital, Tangshan, China. yibin07@sina.com.
authors.forename: Yibin
authors.initials: Y
authors.lastname: Cao
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. yilong528@gmail.com.|China National Clinical Research Center for Neurological Diseases, Beijing, China. yilong528@gmail.com.|Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China. yilong528@gmail.com.|Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China. yilong528@gmail.com.
authors.forename: Yilong
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000368:Aged; D002681:China / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000706:statistics & numerical data*; D012008:Recurrence; D012042:Registries / Q000706:statistics & numerical data*; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy