title: [Residual pleural opacity in patients treated for pleural tuberculosis in Yaounde].
abstract: BACKGROUND
  The aim of this study was to evaluate the incidence and risk factors of residual pleural opacity (RPO) at the end and after 6 months (M12) of antituberculosis treatment (ATT) in adults with pleural tuberculosis.
  
  
  METHODS
  In this prospective cohort study, all patients admitted for pleural tuberculosis between September 2010 and August 2012 in the pneumology A unit of Yaounde Jamot Hospital were included. Each patient was then followed up for 12 months. RPO was considered significant if it was measured 10mm or more on standard chest X-ray. The logistic regression model was used to investigate the risk factors of significant RPO at the end of antituberculosis treatment.
  
  
  RESULTS
  Of the 193 patients included, median (interquartile range) age of 33 (25-42) years, 115 (59.6%) were men. The incidence (95% CI) of significant RPO was 22.0% (14.9-29.1) and 11.0% (4.9-17.1) at the end of ATT and at M12 respectively. In multivariate analysis, the risk factors of the occurrence of a significant RPO at the end of ATT and at M12 were smoking, associated parenchymal lesions, and hypoglycopleuria.
  
  
  CONCLUSIONS
  Cumulative incidence of RPO ≥ 10 mm was 22% at the end of ATT and 11% after 12 months from the beginning of treatment. Patients with risk factors of RPO ≥ 10 mm should benefit from greater surveillance and appropriate management.
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Hôpital Jamot de Yaoundé, Yaoundé, Cameroun. Electronic address: dodobalkissou@gmail.com.
authors.forename: A D
authors.initials: AD
authors.lastname: Balkissou
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Hôpital Jamot de Yaoundé, Yaoundé, Cameroun.
authors.forename: E W
authors.initials: EW
authors.lastname: Pefura-Yone
authors.affiliation: Centre de diagnostic d'imagerie médicale et de conseils en radioprotection, Yaoundé, Cameroun.
authors.forename: M
authors.initials: M
authors.lastname: Netong Gamgne
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Hôpital Laquintinie, Douala, Cameroun.
authors.forename: L-M
authors.initials: LM
authors.lastname: Endale Mangamba
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
authors.forename: I
authors.initials: I
authors.lastname: Onana Ngono
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
authors.forename: V
authors.initials: V
authors.lastname: Poka Mayap
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
authors.forename: A
authors.initials: A
authors.lastname: Evouna Mbarga
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
authors.forename: S A
authors.initials: SA
authors.lastname: Assamba Mpom
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
authors.forename: N F
authors.initials: NF
authors.lastname: Kanko
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
authors.forename: G
authors.initials: G
authors.lastname: Fodjeu
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun.
authors.forename: P E
authors.initials: PE
authors.lastname: Tagne Kamdem
authors.affiliation: Hôpital Jamot de Yaoundé, Yaoundé, Cameroun.
authors.forename: D
authors.initials: D
authors.lastname: Fogang
authors.affiliation: Département de médecine interne et spécialités, faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Faculté de sciences de la santé, Bamenda, Cameroun.
authors.forename: C
authors.initials: C
authors.lastname: Kuaban
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002163:Cameroon / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D010994:Pleura / Q000000981:diagnostic imaging / Q000473:pathology; D010996:Pleural Effusion / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000453:epidemiology*; D013902:Radiography, Thoracic; D012008:Recurrence; D017211:Treatment Failure; D014396:Tuberculosis, Pleural / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000453:epidemiology*
chemical_list: D000995:Antitubercular Agents
keywords: Afrique sub-Saharienne; Facteurs de risque; Pleural sequel; Pleural tuberculosis; Risk factors; Sub-Saharan Africa; Séquelle pleurale; Tuberculose pleurale; Yaounde; Yaoundé