title: Induction therapy with a combination of fumarates and cyclosporine: A benefit for the patient?
abstract: Fumarates or fumaric acid esters derivates (FAED) have appeared to be effective and less toxic than other systemic treatments for psoriasis. Due to its safe adverse event profile, FAED can be used as a long-term maintenance therapy. One of the greatest reasons why FAED are not preferred as a first-line treatment is that according to the recommended dosing schedule, clinically meaningful improvement is seen just after 6 to 8 weeks of therapy. In this manuscript, we suppose an alternative induction scheme with a combination therapy of fumarates and cyclosporine for a more rapid improvement and better compliance.
authors.affiliation: a Department of Dermatology , Albert Schweitzer Hospital , Dordrecht , the Netherlands and.|b Department of Dermatology , Erasmus Medical Center , Rotterdam , the Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Fallah Arani
authors.affiliation: b Department of Dermatology , Erasmus Medical Center , Rotterdam , the Netherlands.
authors.forename: H A M
authors.initials: HA
authors.lastname: Neumann
authors.affiliation: b Department of Dermatology , Erasmus Medical Center , Rotterdam , the Netherlands.
authors.forename: H B
authors.initials: HB
authors.lastname: Thio
mesh_terms: D016572:Cyclosporine / Q000008:administration & dosage*; D004359:Drug Therapy, Combination / Q000379:methods*; D005650:Fumarates / Q000008:administration & dosage*; D006801:Humans; D010349:Patient Compliance; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D005650:Fumarates; D016572:Cyclosporine
keywords: Fumarates; combination; cyclosporine; fumaric acid esters derivates; psoriasis; therapy; treatment