title: Lewis Acid Mediated Vinylogous Additions of Enol Nucleophiles into an α,β-Unsaturated Platinum Carbene.
abstract: A variety of substituted indoles and benzofurans are accessed via a platinum catalyzed annulation and vinylogous addition of enol nucleophiles. Several β-dicarbonyl compounds participate in the reaction, as do α-nitro and α-cyano carbonyl species. Subjecting the indole products to acidic conditions results in the formation of fused heterocycles.
authors.affiliation: Department of Chemistry, University of Georgia , Athens, Georgia 30602, United States.
authors.forename: Paul A
authors.initials: PA
authors.lastname: Allegretti
authors.affiliation: Department of Chemistry, University of Georgia , Athens, Georgia 30602, United States.
authors.forename: Khoi
authors.initials: K
authors.lastname: Huynh
authors.affiliation: Department of Chemistry, University of Georgia , Athens, Georgia 30602, United States.
authors.forename: Tarik J
authors.initials: TJ
authors.lastname: Ozumerzifon
authors.affiliation: Department of Chemistry, University of Georgia , Athens, Georgia 30602, United States.
authors.forename: Eric M
authors.initials: EM
authors.lastname: Ferreira
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D058116:Lewis Acids / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D010984:Platinum / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D007211:Indoles; D058116:Lewis Acids; C030011:carbene; D010984:Platinum; D008697:Methane