title: A review on biological sources, chemistry and pharmacological activities of pinostrobin.
abstract: Pinostrobin, a dietary bioflavonoid discovered more than 6 decades ago in the heart-wood of pine (Pinus strobus), has depicted many pharmacological activities including anti-viral, anti-oxidant, anti-leukaemic, anti-inflammatory and anti-aromatase activities. It is an inhibitor of sodium channel and Ca(2+) signalling pathways and also inhibits intestinal smooth muscle contractions. In spite of the fact that pinostrobin has an application as functional foods, till-to-date no comprehensive review on pinostrobin has been carried out. Hence, the present review deals with the biological sources, chemistry and pharmacological activities of pinostrobin.
authors.affiliation: a Department of Natural Products , National Institute of Pharmaceutical Education and Research (NIPER) , Mohali , India.
authors.forename: Neeraj K
authors.initials: NK
authors.lastname: Patel
authors.affiliation: a Department of Natural Products , National Institute of Pharmaceutical Education and Research (NIPER) , Mohali , India.
authors.forename: Gaurav
authors.initials: G
authors.lastname: Jaiswal
authors.affiliation: a Department of Natural Products , National Institute of Pharmaceutical Education and Research (NIPER) , Mohali , India.
authors.forename: Kamlesh K
authors.initials: KK
authors.lastname: Bhutani
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D000998:Antiviral Agents / Q000494:pharmacology; D047072:Aromatase Inhibitors / Q000494:pharmacology; D044950:Flavanones / Q000096:biosynthesis / Q000737:chemistry / Q000494:pharmacology*; D055951:Functional Food; D006801:Humans; D028223:Pinus / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D000975:Antioxidants; D000998:Antiviral Agents; D047072:Aromatase Inhibitors; D044950:Flavanones; D010936:Plant Extracts; C411294:pinostrobin
keywords: Pinostrobin; anti-cancer; anti-inflammatory; anti-viral; flavanones; functional foods