title: Embolic stroke secondary to spontaneous thrombosis of unruptured intracranial aneurysm: Report of three cases.
abstract: Intracranial aneurysms uncommonly present with ischemic stroke. Parent artery occlusion due to local extension of the luminal thrombus, aneurysms ejecting emboli to distal arteries, or increased mass effect have been described as possible pathogenic mechanisms. Guidelines for the management of these patients are absent. We present the clinical outcome and radiological characteristics of three patients with spontaneous thrombosis of intracranial aneurysms as a cause of ischemic stroke. This information is relevant given the possible benign history in terms of stroke recurrence and risk of bleeding.
authors.affiliation: Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suarez, Mexico.
authors.forename: Antonio
authors.initials: A
authors.lastname: Arauz
authors.affiliation: Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suarez, Mexico hemaparo@yahoo.com.
authors.forename: Hernán M
authors.initials: HM
authors.lastname: Patiño-Rodríguez
authors.affiliation: Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suarez, Mexico.
authors.forename: Mónica
authors.initials: M
authors.lastname: Chavarría-Medina
authors.affiliation: Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suarez, Mexico.
authors.forename: Mayra
authors.initials: M
authors.lastname: Becerril
authors.affiliation: Johns Hopkins Community Physicians, USA.
authors.forename: José G
authors.initials: JG
authors.lastname: Merino
authors.affiliation: Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suarez, Mexico.
authors.forename: Marco
authors.initials: M
authors.lastname: Zenteno
mesh_terms: D000328:Adult; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000150:complications / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000473:pathology / Q000628:therapy; D002532:Intracranial Aneurysm / Q000150:complications* / Q000601:surgery / Q000628:therapy; D020767:Intracranial Thrombosis / Q000209:etiology* / Q000628:therapy; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D012008:Recurrence; D020521:Stroke / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome
keywords: Ischemic stroke; thrombosis; unruptured aneurysm