title: Hybrid Neurofibroma/Schwannoma of the Supraorbital Nerve: Clinicopathologic Correlation of a Rare Tumor.
abstract: Benign peripheral nerve sheath tumors such as schwannoma and neurofibroma have long been considered distinct entities. Recently, hybrid tumors demonstrating combined morphological features of neurofibroma and schwannoma have been described, primarily in dermal locations. Only 1 case of hybrid peripheral nerve sheath tumor of the orbit has been reported in the literature. Hybrid morphology is important to recognize because of its association with the neurofibromatoses, including schwannomatosis; however, the paucity of literature on orbital hybrid peripheral nerve sheath tumor poses a diagnostic challenge. This article describes a case of hybrid neruofibroma/schwannoma of the orbit arising from the supraorbital nerve with clinicopathologic correlation.
authors.affiliation: *Vanderbilt Eye Institute, Vanderbilt University School of Medicine, Nashville, Tennessee; and †Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, Tennessee, U.S.A.
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Taubenslag
authors.forename: Hilary H
authors.initials: HH
authors.lastname: Nickols
authors.forename: James G
authors.initials: JG
authors.lastname: Chelnis
authors.forename: Louise A
authors.initials: LA
authors.lastname: Mawn
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis*; D009442:Neurilemmoma / Q000175:diagnosis*; D009455:Neurofibroma / Q000175:diagnosis*; D009882:Ophthalmic Nerve / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed