title: Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil.
abstract: Clozapine is known to be an effective antipsychotic for schizophrenia. Cardiovascular complications associated with initiation of clozapine include tachycardia, postural hypotension, and myocarditis. Factors associated with development of cardiovascular adverse events are not clearly known, and dose titration has been described to be one among the associated risk factors. We report a case of a 45-year-old man with treatment resistant schizophrenia who developed supraventricular tachycardia during initiation of clozapine and discuss the role of verapamil in its successful management.
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Jagadeesh V V
authors.initials: JV
authors.lastname: Settem
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Satyakant
authors.initials: S
authors.lastname: Trivedi
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Avinash G
authors.initials: AG
authors.lastname: Kamath
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Rishikesh V
authors.initials: RV
authors.lastname: Behere
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Haridas
authors.initials: H
authors.lastname: Kanaradi
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Sripathy M
authors.initials: SM
authors.lastname: Bhat
keywords: Clozapine; schizophrenia; supraventricular tachycardia; verapamil