title: Comparative evaluation of topical application of turmeric gel and 0.2% chlorhexidine gluconate gel in prevention of gingivitis.
abstract: BACKGROUND
  Turmeric commonly known as "Haldi" is a popular spice frequently used in Indian foods and curry. Turmeric holds a high place in Ayurvedic medicine as a "detoxifier of the body," and today, science has documented several diseased conditions that can be healed by the active ingredients of turmeric. Curcumin is the most active constituent of turmeric curcuminoids obtained from the rhizome of Curcuma longa. Curcumin has been found to have antioxidant, anti-tumor, anti-inflammatory, antiviral, antibacterial, antifungal, analgesic, anti-allergic, antiseptic properties and thus has a potential against various diseases. Due to these properties it was felt that promotion of turmeric in dental practice may prove beneficial.
  
  
  METHODS
  The study was conducted in the Department of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, India. A total of 40 subjects of both the sexes from age group 20-35 years. Simple random sampling was followed and the participants were assigned to two groups 'A' and 'B' of 20 participants each. Group A subjects were advised 0.2% chlorhexidine gluconate gel. Group B 30 subjects were advised experimental (turmeric) gel.
  
  
  METHODS
  Data were summarized as mean ± SD. Pre and post outcome measures of two groups were compared by repeated measures analysis of variance (RM ANOVA) using general linear models (GLM) and the significance of mean difference within and between the groups was done by Bonferroni post hoc test after adjusting for multiple contrasts (comparisons).
  
  
  CONCLUSIONS
  Based on the observations of our study, it can be concluded that chlorhexidine gluconate as well as turmeric gel can be effectively used as an adjunct to mechanical plaque control in prevention of plaque and gingivitis. chlorhexidine gluconate gel has been found to be more effective when antiplaque and anti-inflammatory properties were considered. The effect of turmeric observed may be because of its anti-inflammatory action. The antiplaque action of chlorhexidine gluconate is due to its substantivity. Substantivity of tutmeric is required to be further studied.
authors.affiliation: Department of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Vibha
authors.initials: V
authors.lastname: Singh
authors.affiliation: Department of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Anjani Kumar
authors.initials: AK
authors.lastname: Pathak
authors.affiliation: National Botanical Research Institute, Lucknow, Uttar Pradesh, India.
authors.forename: Mahesh
authors.initials: M
authors.lastname: Pal
authors.affiliation: Department of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Sagar
authors.initials: S
authors.lastname: Sareen
authors.affiliation: Department of Prosthodontics, K.G. Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Kopal
authors.initials: K
authors.lastname: Goel
keywords: Anti-inflammatory; chlorhexidine; turmeric