title: OpenFDA: an innovative platform providing access to a wealth of FDA's publicly available data.
abstract: The objective of openFDA is to facilitate access and use of big important Food and Drug Administration public datasets by developers, researchers, and the public through harmonization of data across disparate FDA datasets provided via application programming interfaces (APIs).
  
  
  
  Using cutting-edge technologies deployed on FDA's new public cloud computing infrastructure, openFDA provides open data for easier, faster (over 300 requests per second per process), and better access to FDA datasets; open source code and documentation shared on GitHub for open community contributions of examples, apps and ideas; and infrastructure that can be adopted for other public health big data challenges.
  
  
  
  Since its launch on June 2, 2014, openFDA has developed four APIs for drug and device adverse events, recall information for all FDA-regulated products, and drug labeling. There have been more than 20 million API calls (more than half from outside the United States), 6000 registered users, 20,000 connected Internet Protocol addresses, and dozens of new software (mobile or web) apps developed. A case study demonstrates a use of openFDA data to understand an apparent association of a drug with an adverse event.
  
  
  
  With easier and faster access to these datasets, consumers worldwide can learn more about FDA-regulated products.
authors.affiliation: U.S. Food and Drug Administration, Silver Spring, MD, USA.
authors.forename: Taha A
authors.initials: TA
authors.lastname: Kass-Hout
authors.affiliation: U.S. Food and Drug Administration, Silver Spring, MD, USA zhiheng.xu@fda.hhs.gov.
authors.forename: Zhiheng
authors.initials: Z
authors.lastname: Xu
authors.affiliation: Iodine, Inc. 34 Clyde Street, San Francisco, CA 94107, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Mohebbi
authors.affiliation: Iodine, Inc. 34 Clyde Street, San Francisco, CA 94107, USA.
authors.forename: Hans
authors.initials: H
authors.lastname: Nelsen
authors.affiliation: Iodine, Inc. 34 Clyde Street, San Francisco, CA 94107, USA.
authors.forename: Adam
authors.initials: A
authors.lastname: Baker
authors.affiliation: U.S. Food and Drug Administration, Silver Spring, MD, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Levine
authors.affiliation: U.S. Food and Drug Administration, Silver Spring, MD, USA.
authors.forename: Elaine
authors.initials: E
authors.lastname: Johanson
authors.affiliation: U.S. Food and Drug Administration, Silver Spring, MD, USA.
authors.forename: Roselie A
authors.initials: RA
authors.lastname: Bright
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D066264:Datasets as Topic; D004348:Drug Labeling; D033161:Government Regulation; D010067:Ownership; D057051:Product Recalls and Withdrawals; D012984:Software; D014481:United States; D014486:United States Food and Drug Administration
keywords: API; adverse event; application programming interface; drug safety; open data; open source; openFDA