title: [Prurigo nodularis--pregabalin can be considered for more severe symptoms].
abstract: Prurigo nodularis is a pruritic condition characterized by skin noduli. Different treatment options have been used with limited success. Pregabalin is a drug licensed for treatment of neuropathic pain in adults. As prurigo nodularis involves suffering for the patients and is difficult to treat, the aim of this case report is to report the effect of pregabalin treatment in seven patients with prurigo nodularis, treated in the dermatology clinic in Malmö, Sweden. Four patients experienced good effect of pregabalin, though two patients had a transient effect. Side effects of pregabalin have been reported. This case report indicates that pregabalin is a treatment option for therapy-resistant prurigo nodularis; even though one must be aware of that the effect may not be permanent and that there are side effects. The aim must be to use the drug for a limited time, taking the patient to a remission state, where the vicious itch-scratch cycle can be inhibited.
authors.affiliation: Hudklinken - Skånes Universitetssjukhus Malmö, Sweden Capio Citykliniken - Centrum Malmö, Sweden.
authors.forename: Monika
authors.initials: M
authors.lastname: Asplund
authors.affiliation: Centrum för Primärvårdsforskning - Clinical Research Centre (CRC), Skånes Universitetssjukhus Malmö, Sweden Centrum för Primärvårdsforskning - Clinical Research Centre (CRC), Skånes Universitetssjukhus Malmö, Sweden.
authors.forename: Susanna
authors.initials: S
authors.lastname: Calling
authors.affiliation: Hudklinken - Skånes Universitetssjukhus Malmö, Sweden Hudklinken - Skånes Universitetssjukhus Malmö, Sweden.
authors.forename: Anna
authors.initials: A
authors.lastname: Spirén
authors.affiliation: Yrkes- och miljödermatologiska avdelningen - Skåne Universitetssjukhus Malmö, Sweden Yrkes- och miljödermatologiska avdelningen - Skåne Universitetssjukhus Malmö, Sweden.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Svedman
mesh_terms: D000328:Adult; D000368:Aged; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069583:Pregabalin / Q000008:administration & dosage / Q000627:therapeutic use*; D011536:Prurigo / Q000188:drug therapy*
chemical_list: D002121:Calcium Channel Blockers; D000069583:Pregabalin