title: Kidney Function Evaluation According to Percentage of Technetium-99m Capture With Addition of Correcting Factor for Technetium-99mm Decay.
abstract: OBJECTIVE
  Assess the safety and accuracy of renal static scintigraphy with introduction of the amendment coefficient for decay of 99m metastable (Tc-99m) at the calculation formula of capture percent Technemec 99m.
  
  
  METHODS
  This study analyzes retrospectively the results of renal static scanning of 44 patients. Of this group of patients, 21 are Chornobyl Nuclear Power Station accident liquid ators who have arterial hypertension and chronic pyelonephritis. Renal scanning was carried out with Genesys EPIC single-photon emission computed tomography system. Calculation of the capture percent of the radiopharmaceutical Technemec 99m was executed in the standard way with introduction of the amendment coefficient Tc-99m to decay at the calculation formula of capture percentage Technemec.
  
  
  RESULTS
  Significant differences by standard calculation method took place in the both the Chornobyl Nuclear Power Station accident liquidators and persons who were not subjected to the influence of a small radiation dosage (P < .05).
  
  
  CONCLUSIONS
  A small radiation dose did not affect kidney function (P > .05) with introduction of the amendment coefficient for decay of technetium 99m; therefore, static scintigraphy is a safe method for assessing kidney structure and morphology. Introduction of amendment for decay of Tc-99m allowed false positive results in 11.9% of renal function assessments for patients with arterial hypertension and kidney dysfunction (P < .05). Calculation of the specific capture percent of radiopharmaceutical on 1 cm2 of visualization of renal parenchyma enabled a 29% increase in renal function identification accuracy.
authors.affiliation: From the Department of Science Management, National Research Medical Center, Astana, Kazakhstan.
authors.forename: Gulziya
authors.initials: G
authors.lastname: Ismailova
mesh_terms: D000328:Adult; D047852:Chernobyl Nuclear Accident; D003430:Cross-Sectional Studies; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000503:physiopathology; D007677:Kidney Function Tests; D008297:Male; D011237:Predictive Value of Tests; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012189:Retrospective Studies; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid