title: [Repair surgical defect of squamous cell carcinoma of tongue base with advanced patients].
abstract: OBJECTIVE
  To repair the postoperative tissue detect of the base of tongue cancer in advanced patients.
  
  
  METHODS
  There were 30 patients of medium-high differentiation squamous cell carcinoma(SCC) included in this study. According to the TNM staging of AJCC 2002, there were 4 cases of T2N1M0, 7 of T3N1M0, 10 of T3N2M0, 4 of T4N1M0 and 5 of T4N2M0. Surgical approach of the primary lesion: 12 with transhyoidpharyngotomy approach and 18 with mandibulotomy approach. All cases accepted radiotherapy 4-6 weeks after surgery.
  
  
  RESULTS
  Twenty-five cases were reconstructed with pedicle pectoralis major myocutaneous flaps, and all them survived. Among them, 1 flap was partial split with surrounding tissue spontaneously, and another flap had partial tissue necrosis, however, both flaps grew well with dressing and other local treatment. Other 5 cases were reconstructed with free anterolateral myocutaneous flaps. Among them, 1 flap had partial tissue necrosis, but had a secondary healing after removing necrotic tissue via mouth approach. All 18 patients of larynx-preservation had tracheal tube pulled out. The 3-year survival rate was 68% and the local control rate was 87%.
  
  
  CONCLUSIONS
  Pedicle pectoralis major myocutaneous flaps and free anterolateral myocutaneous flaps were alternative donor area for repairing postoperative tissue defect of the base of tongue; The former was preferred, and the latter was concealed so as to be a kind of effective method, which need adept technique of microsurgery.
authors.forename: Qian
authors.initials: Q
authors.lastname: Cai
authors.forename: Jieren
authors.initials: J
authors.lastname: Peng
authors.forename: Zhong
authors.initials: Z
authors.lastname: Guan
authors.forename: Faya
authors.initials: F
authors.lastname: Liang
authors.forename: Ping
authors.initials: P
authors.lastname: Han
authors.forename: Renhui
authors.initials: R
authors.lastname: Chen
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Huang
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D058752:Free Tissue Flaps; D006801:Humans; D007830:Larynx; D064827:Myocutaneous Flap; D009367:Neoplasm Staging; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D019651:Plastic Surgery Procedures / Q000379:methods*; D015996:Survival Rate; D014059:Tongue / Q000473:pathology / Q000601:surgery; D014062:Tongue Neoplasms / Q000601:surgery*