title: Prediction of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma by Using Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio.
abstract: OBJECTIVE
  To assess the levels of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with pseudoexfoliation syndrome (PEX) and to compare the NLR and PLR results of patients with PEX, PEX glaucoma (PXG), and healthy controls.
  
  
  METHODS
  In total, 34 patients with PEX, 29 patients with PXG, and 42 healthy subjects were enrolled in this retrospective study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 2 h of blood collection.
  
  
  RESULTS
  There was a significant difference in NLR between PEX and control groups (p = 0.012) and PXG and control groups (p = 0.003). Also, a significant difference was found in PLR values between control and PXG groups (p = 0.024).
  
  
  CONCLUSIONS
  Our study for the first time provides evidence that PLR and NLR may be useful for predicting the prognosis of PEX patients and progression to PXG.
authors.affiliation: a Van Military Hospital , Department of Ophthalmology , Van , Turkey.
authors.forename: Cem
authors.initials: C
authors.lastname: Ozgonul
authors.affiliation: b Ankara Mevki Military Hospital, Anittepe Dispensary , Biochemistry Laboratory , Ankara , Turkey.
authors.forename: Erdim
authors.initials: E
authors.lastname: Sertoglu
authors.affiliation: c Gulhane Military Medical Academy , Department of Ophthalmology , Ankara , Turkey.
authors.forename: Tarkan
authors.initials: T
authors.lastname: Mumcuoglu
authors.affiliation: c Gulhane Military Medical Academy , Department of Ophthalmology , Ankara , Turkey.
authors.forename: Gokhan
authors.initials: G
authors.lastname: Ozge
authors.affiliation: d Kayseri Military Hospital , Department of Ophthalmology , Kayseri , Turkey.
authors.forename: Gokcen
authors.initials: G
authors.lastname: Gokce
mesh_terms: D001792:Blood Platelets / Q000166:cytology; D017889:Exfoliation Syndrome / Q000175:diagnosis* / Q000473:pathology*; D005901:Glaucoma / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000166:cytology; D009504:Neutrophils / Q000166:cytology; D012189:Retrospective Studies
keywords: Glaucoma; inflammation; neutrophil to lymphocyte ratio; platelet to lymphocyte ratio; pseudoexfoliation syndrome