title: Does pregnancy influence long-term results of bariatric surgery?
abstract: BACKGROUND
  Bariatric surgery is performed mostly on obese women of reproductive age. Many authors have studied pregnancy outcomes after bariatric surgery. Only a small number of studies have analyzed the impact of maternity on the results of bariatric surgery.
  
  
  OBJECTIVE
  To study the effect of pregnancy on long-term outcomes of bariatric surgery.
  
  
  METHODS
  Lille University Hospital.
  
  
  METHODS
  A retrospective study was conducted on 591 women aged 18 to 42 years who had undergone laparoscopic adjustable gastric band (LAGB) surgery or laparoscopic Roux-en-Y gastric bypass (LRYGB) surgery between 1996 and 2012. A comparison of the results after a 5-year follow-up was performed between patients who became pregnant after their bariatric surgery (pregnant group, n = 84) and postoperative nonpregnant women (nonpregnant group, n = 507).
  
  
  RESULTS
  At the 5-year visit, 84.8% patients were seen. The preoperative body mass index (BMI) was the same in the 2 groups (pregnant group: 47.8±6.9 kg/m(2); nonpregnant group: 47.5±7.2 kg/m(2); P = .755). The percentage of excess weight loss (%EWL) was lower in the pregnant group at 2 years (pregnant group = 45.9±24.6%; nonpregnant group = 56.9±28.6%, P = .002) but was similar at 5 years (47.7±27.7% versus 49.9±28.9%, P = .644). The decrease in co-morbidities was similar after 5 years. The gestational weight gain (GWG) was higher when the band was deflated during pregnancy (GWG =+12.7±10.5 kg) compared to the band without fluid removal (GWG =+4.9±7 kg) or laparoscopic Roux-en-Y gastric bypass (GWG =+4.4±1.1 kg) (P< .05).
  
  
  CONCLUSIONS
  Pregnancy after bariatric surgery slows down postoperative weight loss but does not affect weight results at 5-year follow-up.
authors.affiliation: General Surgery and Endocrine, Huriez Hospital, Lille, France; Lille University Hospital, Lille, France.
authors.forename: Thu
authors.initials: T
authors.lastname: Quyên Pham
authors.affiliation: General Surgery and Endocrine, Huriez Hospital, Lille, France; Lille University Hospital, Lille, France; Department of Nutrition - Obesity Unit, Huriez Hospital, Lille, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Pigeyre
authors.affiliation: General Surgery and Endocrine, Huriez Hospital, Lille, France; Lille University Hospital, Lille, France.
authors.forename: Robert
authors.initials: R
authors.lastname: Caiazzo
authors.affiliation: General Surgery and Endocrine, Huriez Hospital, Lille, France; Lille University Hospital, Lille, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Verkindt
authors.affiliation: General Surgery and Endocrine, Huriez Hospital, Lille, France; Lille University Hospital, Lille, France; Department of Gynecology - Obstetrics, Jeanne de Flandres Hospital, Lille, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Deruelle
authors.affiliation: General Surgery and Endocrine, Huriez Hospital, Lille, France; Lille University Hospital, Lille, France. Electronic address: fpattou@univ-lille2.fr.
authors.forename: François
authors.initials: F
authors.lastname: Pattou
mesh_terms: D000328:Adult; D050110:Bariatric Surgery / Q000009:adverse effects / Q000379:methods*; D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D005602:France; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods; D008991:Monitoring, Physiologic / Q000379:methods; D009767:Obesity, Morbid / Q000175:diagnosis / Q000601:surgery*; D061214:Patient Safety; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D018570:Risk Assessment; D013997:Time Factors; D016896:Treatment Outcome; D015431:Weight Loss / Q000502:physiology*; D055815:Young Adult
keywords: Bariatric surgery; Outcomes; Pregnancy; Weight loss