title: Synthesis of quinoline-3-carboxylates by a Rh(II)-catalyzed cyclopropanation-ring expansion reaction of indoles with halodiazoacetates.
abstract: In this letter, we report a novel synthesis of ethyl quinoline-3-carboxylates from reactions between a series of indoles and halodiazoacetates. The formation of the quinoline structure is probably the result of a cyclopropanation at the 2- and 3-positions of the indole followed by ring-opening of the cyclopropane and elimination of H-X.
authors.affiliation: Department of Chemistry, University of Oslo, P.O. Box 1033 Blindern, NO-0315 Oslo, Norway.
authors.forename: Magnus
authors.initials: M
authors.lastname: Mortén
authors.affiliation: Department of Chemistry, University of Oslo, P.O. Box 1033 Blindern, NO-0315 Oslo, Norway.
authors.forename: Martin
authors.initials: M
authors.lastname: Hennum
authors.affiliation: Department of Chemistry, University of Oslo, P.O. Box 1033 Blindern, NO-0315 Oslo, Norway.
authors.forename: Tore
authors.initials: T
authors.lastname: Bonge-Hansen
keywords: Rh(II); catalysis; cyclopropanation; indole; quinoline; ring expansion