title: Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Complex in Patients with Optic Neuritis or Neuromyelitis Optica Spectrum Disorders Using Optical Coherence Tomography in a Chinese Cohort.
abstract: We evaluate a cohort of optic neuritis and neuromyelitis optica (NMO) spectrum disorders patients in a territory hospital in China. The peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell complex (GCC) were measured using spectral-domain OCT after 6 months of acute onset. The results showed that both the peripapillary RNFL and macular GCC were significantly thinner in all optic neuritis subtypes compared to controls. In addition, the recurrent optic neuritis and NMO groups showed more severe damage on the RNFL and GCC pattern.
authors.affiliation: Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai 200031, China.
authors.forename: Guohong
authors.initials: G
authors.lastname: Tian
authors.affiliation: Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Zhenxin
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Guixian
authors.initials: G
authors.lastname: Zhao
authors.affiliation: Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai 200031, China.
authors.forename: Chaoyi
authors.initials: C
authors.lastname: Feng
authors.affiliation: Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai 200031, China.
authors.forename: Mengwei
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai 200031, China.
authors.forename: Yongheng
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Department of Ophthalmology, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai 200031, China.
authors.forename: Xinghuai
authors.initials: X
authors.lastname: Sun