title: [Diagnosis and treatment of ovotesticular disorder of sex development: A report of 2 cases].
abstract: OBJECTIVE
  To investigate the characteristics, diagnosis, and treatment of ovotesticular disorder of sex development (OT-DSD).
  
  
  METHODS
  We retrospectively analyzed 2 cases of OT-DSD treated in our hospital. The patients were 19 and 15 years old, respectively, and both received systematic physical examination and examinations of the karyotype, sex hormone, adrenocorticotropic hormone (ACTH), color Doppler ultrasonography, urethrocystoscopy, and human chorionic gonadotropin (HCG) test. Under the laparoscope, we performed surgical gonad exploration, gonadectomy, and vulvar orthopedics. Intraoperative exploration and pathology confirmed true hermaphroditism in both cases, with sex selection as female. One underwent laparoscopic resection of the ovotestis, and the other removal of the testis with the ovarian tissue reserved.
  
  
  RESULTS
  The patients were followed up for 12 months postoperatively, which found no abnormality in either the vulvas or the genital glands.
  
  
  CONCLUSIONS
  Surgical exploration of the gonad is the only method for the diagnosis of OT-DSD and sex selection is the key to treatment. Laparoscopic surgical exploration of the gonad and vulvar orthopedics are the first treatment options.
authors.forename: Jing-qi
authors.initials: JQ
authors.lastname: Wang
authors.forename: Dong-wen
authors.initials: DW
authors.lastname: Wang
authors.forename: Chun
authors.initials: C
authors.lastname: Liu
authors.forename: Hua
authors.initials: H
authors.lastname: Yang
authors.forename: Ji-xiu
authors.initials: JX
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D006063:Chorionic Gonadotropin; D005260:Female; D012739:Gonadal Steroid Hormones; D006801:Humans; D059785:Karyotype; D010535:Laparoscopy; D008297:Male; D010053:Ovary; D050090:Ovotesticular Disorders of Sex Development / Q000175:diagnosis* / Q000601:surgery*; D012189:Retrospective Studies; D013737:Testis / Q000601:surgery; D055815:Young Adult
chemical_list: D006063:Chorionic Gonadotropin; D012739:Gonadal Steroid Hormones