title: Assessment of therapeutic options for reducing alkali burn-induced corneal neovascularization and inflammation.
abstract: This article aims to review and provide the current knowledge of the possibilities of topical treatment of corneal neovascularization due to alkali burns, evidenced by laboratory experiments, in vitro studies, and clinical trials published in the specialized literature. Authors present clinically relevant treatment of corneal neovascularization used in clinical practice, potential antiangiogenic topical therapeutics against corneal neovascularization, which are under investigation, and anti-angiogenic gene-therapy.
authors.affiliation: Department of Pediatric Ophthalmology and Strabismus, Medical University of Bialystok, Bialystok, Poland.
authors.forename: Alina
authors.initials: A
authors.lastname: Bakunowicz-Łazarczyk
authors.affiliation: Department of Pediatric Ophthalmology and Strabismus, Medical University of Bialystok, Bialystok, Poland. Electronic address: urbanbea@umb.edu.pl.
authors.forename: Beata
authors.initials: B
authors.lastname: Urban
mesh_terms: D000287:Administration, Topical; D000468:Alkalies; D016510:Corneal Neovascularization / Q000139:chemically induced* / Q000628:therapy*; D005126:Eye Burns / Q000139:chemically induced* / Q000628:therapy*; D015316:Genetic Therapy; D006801:Humans; D007249:Inflammation / Q000150:complications* / Q000628:therapy*
chemical_list: D000468:Alkalies
keywords: Alkali burn; Corneal neovascularization; Treatment