title: [Cervical cancer is a clinical challenge].
abstract: Cervical cancer is the third most common female cancer world wide. In Sweden, some 450 cases are diagnosed annually. One out of three affected Swedish women is under the age of 40. Survival for all stages is 73 % in Sweden. Human papilloma virus (HPV) can be detected in the majority of all cervical cancers. Treatment consists of surgery for early stages, and a combination of chemoradiation and brachytherapy for locally advanced disease. For metastatic disease, the treatment is palliative. Late side effects after treatment may have serious impact on the quality of life. There is a strong need for more efficient treatment of metastatic disease. Current lines of research include surgical strategies, optimised radiotherapy, neoadjuvant therapy, targeted therapy, and immunotherapy including therapeutic vaccines.
authors.affiliation: Skåne University Hospital - Lund, Sweden - Lund, Sweden.
authors.forename: Maria
authors.initials: M
authors.lastname: Bjurberg
authors.affiliation: Karolinska University Hospital - Stockholm, Sweden Department of Oncology - Stockholm, Sweden.
authors.forename: Catharina
authors.initials: C
authors.lastname: Beskow
authors.affiliation: SKåne University Hospital - Lund, Sweden SKåne University Hospital - Lund, Sweden.
authors.forename: Päivi
authors.initials: P
authors.lastname: Kannisto
authors.affiliation: Linköping University Hospital - Linköping, Sweden Linköping University Hospital - Linköping, Sweden.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Lindahl
mesh_terms: D005260:Female; D006801:Humans; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000145:classification / Q000175:diagnosis / Q000628:therapy