title: Hydrogen peroxide-responsive micelles self-assembled from a peroxalate ester-containing triblock copolymer.
abstract: A novel ABA triblock copolymer by using peroxalate esters as linkages was synthesized. In water, this amphiphilic copolymer self-assembled into micelles which were used as drug delivery carriers. When stimulated with hydrogen peroxide, the micelles disassembled to release drugs since the responsive peroxalate ester linkages would be cleaved after the reaction with hydrogen peroxide.
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Chao
authors.initials: C
authors.lastname: Liu
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Zhu
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Wang
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Dandan
authors.initials: D
authors.lastname: Miao
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Liang
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Cuiwei
authors.initials: C
authors.lastname: Wang
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Liyun
authors.initials: L
authors.lastname: Pang
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Hongfan
authors.initials: H
authors.lastname: Sun
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Deling
authors.initials: D
authors.lastname: Kong
authors.affiliation: TianJin key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Science, Tianjin 300192, P. R. China. yangjing37@hotmail.com.
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
mesh_terms: D004337:Drug Carriers / Q000737:chemistry* / Q000378:metabolism; D016503:Drug Delivery Systems / Q000379:methods*; D004952:Esters; D006861:Hydrogen Peroxide / Q000737:chemistry*; D008823:Micelles; D010070:Oxalates / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
chemical_list: D004337:Drug Carriers; D004952:Esters; D008823:Micelles; D010070:Oxalates; D011108:Polymers; D006861:Hydrogen Peroxide