title: Ligand-Controlled Divergent C-H Functionalization of Aldehydes with Enynes by Cobalt Catalysts.
abstract: We describe a highly step and atom economical cobalt-catalyzed cyclization of 1,6-enynes with aldehydes to synthesize functionalized pyrrolidines and dihydrofurans with high chemo- and stereoselectivity. The catalytic reaction plausibly proceeds via the cobaltacycle intermediate generated from the reaction of enyne substrate with cobalt catalyst, followed by switchable C-H functionalization of weakly coordinating aldehydes depending on the electronic nature of the ligand.
authors.affiliation: Department of Chemistry, National Tsing Hua University , Hsinchu 30013, Taiwan.
authors.forename: Rajagopal
authors.initials: R
authors.lastname: Santhoshkumar
authors.affiliation: Department of Chemistry, National Tsing Hua University , Hsinchu 30013, Taiwan.
authors.forename: Subramaniyan
authors.initials: S
authors.lastname: Mannathan
authors.affiliation: Department of Chemistry, National Tsing Hua University , Hsinchu 30013, Taiwan.
authors.forename: Chien-Hong
authors.initials: CH
authors.lastname: Cheng