title: Synthesis and characterization of Co3O4 ultra-nanosheets and Co3O4 ultra-nanosheet-Ni(OH)2 as non-enzymatic electrochemical sensors for glucose detection.
abstract: The present study examines the synthesis of Co3O4 ultra-nanosheets (Co3O4 UNSs) and Co3O4 ultra-nanosheet-Ni(OH)2 (Co3O4 UNS-Ni(OH)2) via solvothermal process and their application as non-enzymatic electrochemical sensors for glucose detection. X-ray diffraction and transmission electron microscopy results confirmed the Co3O4 UNS deposition on Ni(OH)2 surface. The presence of Co3O4 UNSs on Ni (OH) 2 surface improved the sensitivity of glucose detection, from the increase of glucose oxidation peak current at the Co3O4 UNS-Ni(OH)2/glassy carbon electrode (current density: 2000μA·cm(-2)), compared to the Co3O4 UNSs. These results confirmed that Ni(OH)2 on glassy carbon electrode is a sensitive material for glucose detection, moreover the Co3O4 UNSs can increase the interaction and detection of glucose due to their high surface area. The estimated limit of detection (S/N=3) and limit of quantification (S/N=10) of the linear segment (5-40μM) are 1.08μM and 3.60μM respectively. The reproducibility experiments confirmed the feasibility of Co3O4 UNS-Ni(OH)2 for the quantitative detection of certain concentration ranges of glucose.
authors.affiliation: Department of Chemistry, University of Malaya, Kuala Lumpur 50603, Malaysia; Department of Chemistry, Shahid Sherafat, University of Farhangian, 15916 Tehran, Iran. Electronic address: M_R_mahmoudian@yahoo.com.
authors.forename: M R
authors.initials: MR
authors.lastname: Mahmoudian
authors.affiliation: Department of Chemistry, University of Malaya, Kuala Lumpur 50603, Malaysia.
authors.forename: W J
authors.initials: WJ
authors.lastname: Basirun
authors.affiliation: Department of Chemistry, University of Malaya, Kuala Lumpur 50603, Malaysia.
authors.forename: Pei Meng
authors.initials: PM
authors.lastname: Woi
authors.affiliation: Department of Physics, University of Malaya, Kuala Lumpur 50603, Malaysia.
authors.forename: M
authors.initials: M
authors.lastname: Sookhakian
authors.affiliation: Department of Physics, Masjed-Soleiman Branch, Islamic Azad University (I.A.U), Masjed-Soleiman, Iran.
authors.forename: Ramin
authors.initials: R
authors.lastname: Yousefi
authors.affiliation: Department of Chemistry, University of Malaya, Kuala Lumpur 50603, Malaysia.
authors.forename: H
authors.initials: H
authors.lastname: Ghadimi
authors.affiliation: Department of Chemistry, University of Malaya, Kuala Lumpur 50603, Malaysia. Electronic address: Yatimah70@um.edu.my.
authors.forename: Y
authors.initials: Y
authors.lastname: Alias
mesh_terms: D003035:Cobalt / Q000737:chemistry*; D005947:Glucose / Q000032:analysis*; D006878:Hydroxides / Q000737:chemistry*; D008567:Membranes, Artificial; D049329:Nanostructures / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*
chemical_list: D006878:Hydroxides; D008567:Membranes, Artificial; D010087:Oxides; C037473:nickel hydroxide; D003035:Cobalt; D009532:Nickel; D005947:Glucose; C060728:cobalt oxide
keywords: Biosensor; Electrochemical sensing; Glucose; Non-enzymatic sensing