title: Genetics of non syndromic hearing loss.
abstract: Non Syndromic Hearing Loss is an important cause for hearing loss. One in 1000 newborns have some hearing impairment. Over 400 genetic syndromes have been described. Non Syndromic Hearing Loss (NSHL) can be inherited in an Autosomal Dominant, Autosomal Recessive or a Sex Linked fashion. There are several reasons why genetic testing should be done in cases of NSHL, the main reasons being for genetic screening and for planning treatment. This review describes the genes involved in NSHL and the genetic mechanisms involved in the pathogenesis of the disease.
authors.affiliation: Dean & Dy Comdt, Armed Forces Medical College, Pune 411040, India.
authors.forename: M D
authors.initials: MD
authors.lastname: Venkatesh
authors.affiliation: Senior Adviser (Pathology and Molecular Biology), Command Hospital (Air Force), Bengaluru, India.
authors.forename: Nikhil
authors.initials: N
authors.lastname: Moorchung
authors.affiliation: Senior Consultant (Surgery), O/o DGAFMS, New Delhi 110001, India.
authors.forename: Bipin
authors.initials: B
authors.lastname: Puri
keywords: Genetics; Mutations; NSHL