title: Risk factors associated with abscess formation among patient with leg erysipelas (cellulitis) in sub-Saharan Africa: a multicenter study.
abstract: BACKGROUND
  Abscess formation is a frequent local complication of leg erysipelas. In this study we aimed at identifying factors associated with abscess formation of leg erysipelas in patients in sub-Saharan African countries.
  
  
  METHODS
  This is a multicenter prospective study conducted in dermatology units in eight sub-Saharan African countries from October 2013 to September 2014. We performed univariate and multivariate analysis to compare characteristics among the group of patients with leg erysipelas complicated with abscess against those without this complication.
  
  
  RESULTS
  In this study, 562 cases of leg erysipelas were recruited in the eight sub-Saharan African countries. The mean age of patients was 43.67 years (SD =16.8) (Range: 15 to 88 years) with a sex-ratio (M/F) of 5/1. Out of the 562 cases, 63 patients (11.2%) had abscess formation as a complication. In multivariate analysis showed that the main associated factors with this complication were: nicotine addiction (aOR = 3.7; 95 % CI = [1.3 - 10.7]) and delayed antibiotic treatment initiation (delay of 10 days or more) (aOR = 4.6; 95 % CI = [1.8 - 11.8]).
  
  
  CONCLUSIONS
  Delayed antibiotics treatment and nicotine addiction are the main risk factors associated with abscess formation of leg erysipelas in these countries. However, chronic alcohol intake, which is currently found in Europe as a potential risk factor, was less frequent in our study.
authors.affiliation: Service de dermato-vénéréologie, CHU Sylvanus Olympio, Université de Lomé, 08 BP 81056, Lomé 08, Togo. vincent.pitche@gmail.com.
authors.forename: Palokinam Vincent
authors.initials: PV
authors.lastname: Pitché
authors.affiliation: Service de dermato-vénéréologie, CHU Sylvanus Olympio, Université de Lomé, 08 BP 81056, Lomé 08, Togo. barthelemysaka@yahoo.fr.
authors.forename: Bayaki
authors.initials: B
authors.lastname: Saka
authors.affiliation: Service de dermatologie, CHU Le Dantec, Dakar, Université Cheik Anta Diop, Dakar, Sénégal. ahydiatta@yahoo.com.
authors.forename: Ahy Boubacar
authors.initials: AB
authors.lastname: Diatta
authors.affiliation: Service de dermatologie, CNAM, Bamako, Université de Bamako, Bamako, Mali. faye_o@yahoo.fr.
authors.forename: Ousmane
authors.initials: O
authors.lastname: Faye
authors.affiliation: Service de dermatologie-MST, CHU Donka, Conakry, Université de Conakry, Conakry, Guinée. bohfanta2010@yahoo.fr.
authors.forename: Boh Fanta
authors.initials: BF
authors.lastname: Diané
authors.affiliation: Centre de dermatologie, CHU Treichville, Université de Cocody, Cocody, Côte d'Ivoire. sang_abdoulaye@yahoo.fr.
authors.forename: Abdoulaye
authors.initials: A
authors.lastname: Sangaré
authors.affiliation: Service de dermatologie CHU Yaldago Ouédraogo, Ouagadougou, Université de Ouagadougou, Ouagadougou, Burkina Faso. niamba_pascal@yahoo.com.
authors.forename: Pascal
authors.initials: P
authors.lastname: Niamba
authors.affiliation: Service de dermatologie, Clinique universitaire des Montagnes, Bangangté, Cameroun. cmmandengue@udesmontagnes.org.
authors.forename: Christine
authors.initials: C
authors.lastname: Mandengue
authors.affiliation: Service de dermatologie, CHU Bangui, Université de Bangui, Bangui, Centrafrique. kobangleon@yahoo.fr.
authors.forename: Léon
authors.initials: L
authors.lastname: Kobengue
authors.affiliation: Service de dermatologie, CHU Le Dantec, Dakar, Université Cheik Anta Diop, Dakar, Sénégal. kobangueleon@gmail.com.
authors.forename: Assane
authors.initials: A
authors.lastname: Diop
authors.affiliation: Service de dermatologie, CHU Le Dantec, Dakar, Université Cheik Anta Diop, Dakar, Sénégal. lyfaty@yahoo.fr.
authors.forename: Fatimata
authors.initials: F
authors.lastname: Ly
authors.affiliation: Service de dermatologie, CHU Le Dantec, Dakar, Université Cheik Anta Diop, Dakar, Sénégal. mafath@orange.sn.
authors.forename: Mame Thierno
authors.initials: MT
authors.lastname: Dieng
authors.affiliation: Service de dermatologie, CNAM, Bamako, Université de Bamako, Bamako, Mali. adicko@icermali.org.
authors.forename: Alassane
authors.initials: A
authors.lastname: Dicko
authors.affiliation: Service de dermatologie-MST, CHU Donka, Conakry, Université de Conakry, Conakry, Guinée. medsoum7@yahoo.fr.
authors.forename: Maciré Mohamed
authors.initials: MM
authors.lastname: Soumah
authors.affiliation: Service de dermatologie-MST, CHU Donka, Conakry, Université de Conakry, Conakry, Guinée. cissebibi1@gmail.com.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Cissé
authors.affiliation: Centre de dermatologie, CHU Treichville, Université de Cocody, Cocody, Côte d'Ivoire. sarambilal@yahoo.fr.
authors.forename: Sarah Hamdan
authors.initials: SH
authors.lastname: Kourouma
authors.affiliation: Centre de dermatologie, CHU Treichville, Université de Cocody, Cocody, Côte d'Ivoire. isidore.kouassi@yahoo.fr.
authors.forename: Isidore
authors.initials: I
authors.lastname: Kouassi
authors.affiliation: Service de dermato-vénéréologie, CHU Sylvanus Olympio, Université de Lomé, 08 BP 81056, Lomé 08, Togo. taniratou_boukari@yahoo.fr.
authors.forename: Taniratou
authors.initials: T
authors.lastname: Boukari
authors.affiliation: Service de dermato-vénéréologie, CHU Sylvanus Olympio, Université de Lomé, 08 BP 81056, Lomé 08, Togo. sefasyl@yahoo.fr.
authors.forename: Sefako
authors.initials: S
authors.lastname: Akakpo
authors.affiliation: Division de l'Epidémiologie, Ministère de la santé du Togo, Lomé, Togo. mlandoh@yahoo.fr.
authors.forename: Dadja Essoya
authors.initials: DE
authors.lastname: Landoh
authors.affiliation: Service de dermato-vénéréologie, CHU Sylvanus Olympio, Université de Lomé, 08 BP 81056, Lomé 08, Togo. kissemtchangai@yahoo.fr.
authors.forename: Kissem
authors.initials: K
authors.lastname: Tchangaï-Walla
mesh_terms: D000038:Abscess / Q000453:epidemiology* / Q000382:microbiology; D000293:Adolescent; D000328:Adult; D017954:Africa South of the Sahara / Q000453:epidemiology; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004886:Erysipelas / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007866:Leg; D007868:Leg Dermatoses / Q000453:epidemiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D061665:Time-to-Treatment; D014029:Tobacco Use Disorder / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents