title: Helicobacter cinaedi-associated Vertebral Osteomyelitis in an Immunocompetent Patient.
abstract: A 56-year-old previously healthy man was hospitalized due to a 10-day history of neck pain and an elevated C-reactive protein level. Gram-negative spiral bacilli were isolated from his blood, and Helicobacter cinaedi was confirmed using 16S rRNA sequencing. The infectious focus was not identified by initial cervical magnetic resonance imaging (MRI); however, repeated MRI demonstrated prominent high signal intensity in the entire region of the C6-C7 vertebrae and C6/C7 disc space. Furthermore, fluorodeoxyglucose-positron emission tomography/computed tomography showed no significant uptake, other than in the C6-C7 region. The patient was successfully treated with ceftriaxone for six weeks without sequelae.
authors.affiliation: Department of General Internal Medicine, Josai Hospital, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Murata
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Suzuki
authors.forename: Setsu
authors.initials: S
authors.lastname: Sakamoto
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Miki
authors.forename: Emiko
authors.initials: E
authors.lastname: Rimbara
authors.forename: Keigo
authors.initials: K
authors.lastname: Shibayama
authors.forename: Shinobu
authors.initials: S
authors.lastname: Koyama
authors.forename: Kiyoko
authors.initials: K
authors.lastname: Tamai
authors.forename: Yuji
authors.initials: Y
authors.lastname: Yaguchi
authors.forename: Masaki
authors.initials: M
authors.lastname: Tada
mesh_terms: D002097:C-Reactive Protein / Q000032:analysis; D002443:Ceftriaxone / Q000627:therapeutic use; D002574:Cervical Vertebrae / Q000382:microbiology*; D003937:Diagnosis, Differential; D016998:Helicobacter / Q000235:genetics; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000235:genetics; D006801:Humans; D016867:Immunocompromised Host; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D014057:Tomography, X-Ray Computed
chemical_list: D012336:RNA, Ribosomal, 16S; D002443:Ceftriaxone; D002097:C-Reactive Protein