title: Late-onset Anticonvulsant Hypersensitivity Syndrome Mimicking Lymphoma.
abstract: Anticonvulsant hypersensitivity syndrome is a fatal, idiosyncratic drug reaction that is caused by aromatic antiepileptic drugs. This cutaneous drug reaction is also called pseudolymphoma because of its clinical and histological similarities with malignant lymphoma. The primary clinical findings are fever, skin rashes, enlarged lymph nodes, single or multiple internal organ involvement and hematological abnormalities. Typically, anticonvulsant hypersensitivity syndrome occurs 1-8 weeks after drug administration. We herein present the case of a patient who had been on anticonvulsant therapy for five years and died from late-onset anticonvulsant hypersensitivity syndrome.
authors.affiliation: Department of Hematology, Kocaeli University Medical Faculty, Turkey.
authors.forename: Ayfer
authors.initials: A
authors.lastname: Geduk
authors.forename: Elif
authors.initials: E
authors.lastname: Birtas Atesoglu
authors.forename: Ozgur
authors.initials: O
authors.lastname: Mehtap
authors.forename: Esra
authors.initials: E
authors.lastname: Terzi Demirsoy
authors.forename: Burak
authors.initials: B
authors.lastname: Can
authors.forename: Pinar
authors.initials: P
authors.lastname: Tarkun
authors.forename: Abdullah
authors.initials: A
authors.lastname: Hacihanefioglu
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D063926:Drug Hypersensitivity Syndrome / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D013997:Time Factors
chemical_list: D000927:Anticonvulsants