title: Red Blood Cell Spectrin Skeleton in the Spotlight.
abstract: Das et al. recently reported a role for the major merozoite surface protein MSP1 in malarial parasite egress from the red blood cell (RBC). On the basis of these new data and physical considerations, we propose an updated model for the main steps of this essential process for parasite proliferation.
authors.affiliation: University Montpellier, CNRS UMR 5235, Dynamique des Interactions Membranaires Normales et Pathologiques, 34095 Montpellier, France. Electronic address: cbb@univ-montp2.fr.
authors.forename: Catherine
authors.initials: C
authors.lastname: Braun-Breton
authors.affiliation: CNRS UMR 5048, University Montpellier, Centre de Biochimie Structurale, 34090 Montpellier, France.
authors.forename: Manouk
authors.initials: M
authors.lastname: Abkarian
mesh_terms: D004912:Erythrocytes / Q000469:parasitology*; D006801:Humans; D020066:Merozoite Surface Protein 1 / Q000378:metabolism*; D052940:Merozoites / Q000502:physiology*; D010963:Plasmodium falciparum / Q000502:physiology*; D011499:Protein Processing, Post-Translational; D015800:Protozoan Proteins / Q000378:metabolism*; D013049:Spectrin / Q000378:metabolism*; D013381:Subtilisins / Q000378:metabolism*
chemical_list: D020066:Merozoite Surface Protein 1; D015800:Protozoan Proteins; D013049:Spectrin; D013381:Subtilisins
keywords: egress; malaria; membrane curling; spectrin network