title: Novel Oral Anticoagulation Laboratory Monitoring, Interaction and Treatment of Complications.
abstract: The use of novel oral anticoagulation (NOACs) has emerged as an alternative for oral anticoagulation with vitamin-K antagonists in different clinical settings. However, despite the several advantages of these new drugs, there are also several limitations and cautious is recommended in different clinical settings in patients with a high comorbidity index. This review article will describe the current evidence of treatment monitoring, possible drug interaction, and will give an overview about treatment options in case of complications.
authors.affiliation: First Department of Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany, Theodor-Kutzer-Ufer 1-3, D-68167 Mannheim, Germany. aydin.huseynov@umm.de.
authors.forename: Aydin
authors.initials: A
authors.lastname: Huseynov
authors.forename: Stefan
authors.initials: S
authors.lastname: Baumann
authors.forename: Ibrahim
authors.initials: I
authors.lastname: El-Battrawy
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Akin
mesh_terms: D000284:Administration, Oral; D000925:Anticoagulants / Q000009:adverse effects* / Q000097:blood / Q000494:pharmacology; D001777:Blood Coagulation / Q000187:drug effects*; D055808:Drug Discovery; D004347:Drug Interactions; D016903:Drug Monitoring / Q000379:methods*; D006470:Hemorrhage / Q000139:chemically induced / Q000517:prevention & control*; D006801:Humans; D017410:Practice Guidelines as Topic; D014812:Vitamin K / Q000037:antagonists & inhibitors
chemical_list: D000925:Anticoagulants; D014812:Vitamin K