title: [Fourier Transform Infrared Microspectroscopy of Rat Kidney with Regard to Fa- tal Hyperthermia].
abstract: OBJECTIVE
  To observe the chemical groups changing in rat kidney with regard to fatal hyperthermia by Fourier transform infrared microspectroscopy (FTIR-MSP) and to provide a new method to diagnose fatal hyperthermia.
  
  
  METHODS
  Rats were sacrificed by hyperthermia, brainstem injury, massive hemorrhage and asphyxiation and divided into groups. The renal samples were dissected immediately after death. The data of infrared spectroscopy in glomerulus were measured by FTIR-MSP.
  
  
  RESULTS
  The absorbances of 3290, 3070, 2850, 1540 and 1396 cm(-1) significantly increased (P < 0.05), and the ratios of Al650/A3290 and A1650/A1540 significantly decreased (P < 0.05) in group of hyperthermia.
  
  
  CONCLUSIONS
  FTIR-MSP can analyze the changes of chemical groups of kidney as an auxiliary diagnosis for discriminating hyperthermia with other causes of death.
authors.forename: Zhi-jun
authors.initials: ZJ
authors.lastname: Wang
authors.forename: Shan-shan
authors.initials: SS
authors.lastname: Shen
authors.forename: Kai-fei
authors.initials: KF
authors.lastname: Deng
authors.forename: Zhi-qiang
authors.initials: ZQ
authors.lastname: Qin
authors.forename: Ping
authors.initials: P
authors.lastname: Huang
authors.forename: Zhen-yuan
authors.initials: ZY
authors.lastname: Wang
mesh_terms: D000818:Animals; D005334:Fever / Q000401:mortality*; D005583:Fourier Analysis; D007668:Kidney / Q000378:metabolism*; D015591:Microspectrophotometry; D051381:Rats; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*