title: English language version of the S3-consensus guidelines on chronic pancreatitis: Definition, aetiology, diagnostic examinations, medical, endoscopic and surgical management of chronic pancreatitis.
abstract: Chronic pancreatitis is a disease of the pancreas in which recurrent inflammatory episodes result in replacement of pancreatic parenchyma by fibrous connective tissue. This fibrotic reorganization of the pancreas leads to a progressive exocrine and endocrine pancreatic insufficiency. In addition, characteristic complications arise, such as pseudocysts, pancreatic duct obstructions, duodenal obstruction, vascular complications, obstruction of the bile ducts, malnutrition and pain syndrome. Pain presents as the main symptom of patients with chronic pancreatitis. Chronic pancreatitis is a risk factor for pancreatic carcinoma. Chronic pancreatitis significantly reduces the quality of life and the life expectancy of affected patients. These guidelines were researched and compiled by 74 representatives from 11 learned societies and their intention is to serve evidence-based professional training as well as continuing education. On this basis they shall improve the medical care of affected patients in both the inpatient and outpatient sector. Chronic pancreatitis requires an adequate diagnostic workup and systematic management, given its severity, frequency, chronicity, and negative impact on the quality of life and life expectancy.
authors.forename: A
authors.initials: A
authors.lastname: Hoffmeister
authors.forename: J
authors.initials: J
authors.lastname: Mayerle
authors.affiliation: Department of Gastroenterology and Hepatology, University Hospital Basel, Switzerland.
authors.forename: C
authors.initials: C
authors.lastname: Beglinger
authors.affiliation: Department of General, Visceral and Transplantation Surgery, University Hospital, Heidelberg, Ruprecht Karls University, Heidelberg.
authors.forename: M W
authors.initials: MW
authors.lastname: Büchler
authors.affiliation: Dr. von Haunersches Children's Hospital, Ludwig Maximilian University, Munich.
authors.forename: P
authors.initials: P
authors.lastname: Bufler
authors.affiliation: German Society of Digestive and Metabolic Diseases (DGVS), Berlin.
authors.forename: K
authors.initials: K
authors.lastname: Dathe
authors.affiliation: Department of General Internal Medicine, Christian Albrechts University, Kiel.
authors.forename: U R
authors.initials: UR
authors.lastname: Fölsch
authors.affiliation: Surgical Clinic and Polyclinic at the Rechts der Isar Hospital, Technical University, Munich.
authors.forename: H
authors.initials: H
authors.lastname: Friess
authors.affiliation: Department of General, Visceral and Thoracic Surgery at the University Medical Centre Hamburg-Eppendorf.
authors.forename: J
authors.initials: J
authors.lastname: Izbicki
authors.affiliation: Department of Internal Medicine, Specialisation Gastroenterology, Haematology and Oncology, Nephrology German Red Cross (DRK) Hospital Berlin-Köpenick.
authors.forename: S
authors.initials: S
authors.lastname: Kahl
authors.affiliation: General Surgery, Thoracic, Vascular and Transplantation Surgery, University of Rostock.
authors.forename: E
authors.initials: E
authors.lastname: Klar
authors.affiliation: Department of Medicine, Israelitic Hospital Hamburg.
authors.forename: J
authors.initials: J
authors.lastname: Keller
authors.affiliation: Department of General, Visceral and Paediatric Surgery, University Hospital Dusseldorf of the Heinrich Heine University.
authors.forename: W T
authors.initials: WT
authors.lastname: Knoefel
authors.affiliation: Department of Medicine, Israelitic Hospital Hamburg.
authors.forename: P
authors.initials: P
authors.lastname: Layer
authors.affiliation: Surgical Gastroenterology, Gastrocentrum, Karolinska University Hospital Huddinge.
authors.forename: M
authors.initials: M
authors.lastname: Loehr
authors.affiliation: Department for Gastroenterology, Kanton Hospital Liestal, Medical University Clinic.
authors.forename: R
authors.initials: R
authors.lastname: Meier
authors.affiliation: Department of Medicine C at the Hospital of the City Ludwigshafen/Rhine gGmbH.
authors.forename: J F
authors.initials: JF
authors.lastname: Riemann
authors.affiliation: Division of Gastroenterology and Metabolic Disease, Clinics of South Essen.
authors.forename: M
authors.initials: M
authors.lastname: Rünzi
authors.affiliation: Department of Medicine 2 at the Rechts der Isar Hospital, Technical University Munich.
authors.forename: R M
authors.initials: RM
authors.lastname: Schmid
authors.affiliation: Institute for Radiodiagnostics at the University Hospital of Regensburg.
authors.forename: A
authors.initials: A
authors.lastname: Schreyer
authors.affiliation: Internal Medicine IV, Dept. for Gastroenterology and Hepatology, University Hospital Vienna.
authors.forename: B
authors.initials: B
authors.lastname: Tribl
authors.affiliation: Department of General, Visceral and Transplantation Surgery, University Hospital, Heidelberg, Ruprecht Karls University, Heidelberg.
authors.forename: J
authors.initials: J
authors.lastname: Werner
authors.affiliation: Department of Paediatric Medicine, Children's Hospital Munich Schwabing, Technical University of Munich.
authors.forename: H
authors.initials: H
authors.lastname: Witt
authors.forename: J
authors.initials: J
authors.lastname: Mössner
authors.forename: M M
authors.initials: MM
authors.lastname: Lerch
mesh_terms: D002908:Chronic Disease; D016099:Endoscopy, Gastrointestinal / Q000592:standards*; D005858:Germany; D006801:Humans; D010180:Pancreatectomy / Q000592:standards*; D010186:Pancreatic Function Tests / Q000592:standards*; D010195:Pancreatitis / Q000175:diagnosis* / Q000628:therapy*; D017410:Practice Guidelines as Topic; D014481:United States