title: [Advances in diabetic animal models and its application in the traditional Chinese medicine research].
abstract: The high and continuing soaring incidence of diabetes may become a huge obstacle to China's development. The antidiabetic drug development is one way to solve the problem. Animal model is a powerful tool for drug development. This paper compares and analyzes the three kinds of animal models for antidiabetic drug development in replicating principle, methods and characteristic, then summarized the application in the research of traditional Chinese medicine. At the same time, the analysis of the market, application and clinical advantages of hypoglycemic medicine from traditional Chinese medicine, is given in this paper, based on the literature analysis. From the point of the clinic advantage embodiment and new drug development, this paper will provide advisory and assistance support for the anti-diabetic fighting with traditional Chinese medicine.
authors.forename: Long
authors.initials: L
authors.lastname: Cheng
authors.forename: Zhu-fang
authors.initials: ZF
authors.lastname: Shen
authors.forename: Gui-bo
authors.initials: GB
authors.lastname: Sun
authors.forename: Xiao-bo
authors.initials: XB
authors.lastname: Sun
mesh_terms: D000818:Animals; D002681:China; D003920:Diabetes Mellitus / Q000188:drug therapy*; D004195:Disease Models, Animal; D055808:Drug Discovery; D006801:Humans; D007004:Hypoglycemic Agents; D008516:Medicine, Chinese Traditional
chemical_list: D007004:Hypoglycemic Agents