title: [Cervical cancer in Mecklenburg-Western Pomerania. Tumor stage, histological tumor type, age and screening participation of 985 patients].
abstract: BACKGROUND
  In view of the discussion on primary human papillomavirus (HPV) screening it was necessary to evaluate recent and reliable data from the current cytology-based screening program.
  
  
  METHODS
  Since the year 2004 all cases of cervical cancer must be reported to the Joint State Quality Control Commission in Mecklenburg-Western Pomerania, corrected and supplemented by data of the State Cancer Registry. The screening histories of all patients, age, tumor stages and histological tumor types were analyzed.
  
  
  RESULTS
  Over a 10-year period (2004-2013) 985 women with invasive cervical cancer and complete data were identified, of whom 573 patients (58 %) had not had a cervical smear within the past 5 years, an irregular screening history was found in 312 patients (32 %) and 100 patients (10 %) had cervical cancer despite regular participation. In women who did not participate in the screening program, tumor stages T1b and higher were found in 85 %. In the group of women with regular screening 53 % were diagnosed with microinvasive cancer and in 38 % of women with irregular screening. The age distribution showed a peak for cervical cancer in the age group of 40-54 years. Squamous cell carcinoma dominated and adenocarcinoma was found in 17 % which showed a tendency to increase over the investigation time period.
  
  
  CONCLUSIONS
  Most cervical cancers and the advanced stages were found in women who did not participate in the screening program.
authors.affiliation: Praxis für Pathologie, Güstrower Str. 34, 19055, Schwerin, Deutschland. gynpatho-schwerin@arcor.de.
authors.forename: K
authors.initials: K
authors.lastname: Marquardt
authors.affiliation: Praxis für Pathologie, Rostock, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Stubbe
authors.affiliation: Praxis für Pathologie, Rostock, Deutschland.
authors.forename: U
authors.initials: U
authors.lastname: Broschewitz
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000328:Adult; D000367:Age Factors; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002584:Cervix Uteri / Q000473:pathology; D055088:Early Detection of Cancer; D042241:Early Diagnosis; D005260:Female; D005858:Germany; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology*; D014626:Vaginal Smears
keywords: Adenocarcinoma of the uterine cervix; Cancer screening; Cervical cancer; Cervical cytology; Screening failure