title: Cardiovascular Tissue Engineering: Preclinical Validation to Bedside Application.
abstract: Advancements in biomaterial science and available cell sources have spurred the translation of tissue-engineering technology to the bedside, addressing the pressing clinical demands for replacement cardiovascular tissues. Here, the in vivo status of tissue-engineered blood vessels, heart valves, and myocardium is briefly reviewed, illustrating progress toward a tissue-engineered heart for clinical use.
authors.affiliation: Tissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio;
authors.forename: Cameron
authors.initials: C
authors.lastname: Best
authors.affiliation: Tissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio; Department of Surgery, The Ohio State University, Wexner Medical Center, Columbus, Ohio; and.
authors.forename: Ekene
authors.initials: E
authors.lastname: Onwuka
authors.affiliation: Tissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio; Department of Pediatric Surgery, Nationwide Children's Hospital, Columbus, Ohio.
authors.forename: Victoria
authors.initials: V
authors.lastname: Pepper
authors.affiliation: Tissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio;
authors.forename: Malik
authors.initials: M
authors.lastname: Sams
authors.affiliation: Tissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio;
authors.forename: Jake
authors.initials: J
authors.lastname: Breuer
authors.affiliation: Tissue Engineering and Surgical Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio; Department of Surgery, The Ohio State University, Wexner Medical Center, Columbus, Ohio; and Department of Pediatric Surgery, Nationwide Children's Hospital, Columbus, Ohio Christopher.Breuer@nationwidechildrens.org.
authors.forename: Christopher
authors.initials: C
authors.lastname: Breuer
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D002319:Cardiovascular System / Q000503:physiopathology*; D006801:Humans; D023822:Tissue Engineering
chemical_list: D001672:Biocompatible Materials