title: Trichosporon asahii urinary tract infection in immunocompetent patients.
abstract: Trichosporonosis is an emerging infection predominantly caused by Trichosporon asahii which is a ubiquitous and exclusively anamorphic yeast. T. asahii urinary tract infection is rare and remains scantily reported. T. asahii was isolated from urine of two immunocompetent patients who were receiving in-patient treatment for multiple comorbidities. T. asahii was identified phenotypically by a combination of manual and automated systems. Antifungal susceptibility done by E-test revealed multiresistance with preserved susceptibility to voriconazole. The ubiquity and biofilm formationposes difficulty in establishing pathogenicity and delineating environmental or nosocomial infections. Risk factors such as prolonged multiple antimicrobials, indwelling catheter and comorbidities such as anemia and hypoalbuminemia may be contributory to the establishment of a nosocomial opportunistic T. asahii infection. Dedicated efforts targeted at infection control are needed to optimize management and control of Trichosporon infections.
authors.affiliation: Clinical Microbiologist, Dept of Pathology, Command Hospital (Eastern Command), Kolkata 700027, India.
authors.forename: Inam Danish
authors.initials: ID
authors.lastname: Khan
authors.affiliation: Professor and Head, Dept of Microbiology, Armed Forces Medical College, Pune 411040, India.
authors.forename: Ajay Kumar
authors.initials: AK
authors.lastname: Sahni
authors.affiliation: Senior Advisor & Head, Dept of Pathology, Command Hospital (Eastern Command), Kolkata 700027, India.
authors.forename: Atoshi
authors.initials: A
authors.lastname: Basu
authors.affiliation: Biotechnologist, Martin & Harris Laboratories, New Delhi, India.
authors.forename: Suboohi
authors.initials: S
authors.lastname: Haleem
keywords: Antifungal multiresistance; Nosocomial opportunistic infection; Trichosporon asahii