title: Case series of rhinocerebral mucormycosis occurring in diabetic patients.
abstract: BACKGROUND
  Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%).
  
  
  METHODS
  In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients were isolated and identified by sequence analysis and data were registered in Gene bank database.
  
  
  CONCLUSIONS
  In patients with mucoreosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like diabetes mellitus are the main parameters of successful management of this lethal infection.
authors.affiliation: Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Rasoul
authors.initials: R
authors.lastname: Mohammadi
authors.affiliation: Department of Infectious Diseases, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Meidani
authors.affiliation: Department of Infectious Diseases, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Kamyar
authors.initials: K
authors.lastname: Mostafavizadeh
authors.affiliation: Department of Endocrinology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Bijan
authors.initials: B
authors.lastname: Iraj
authors.affiliation: Department of Endocrinology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Pooria
authors.initials: P
authors.lastname: Hamedani
authors.affiliation: Department of Cardiology, Chamran Hospital (Heart Center), Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Sayed Mohammad Amin
authors.initials: SM
authors.lastname: Sayedain
authors.affiliation: Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mojgan
authors.initials: M
authors.lastname: Mokhtari
keywords: Diabetes Mellitus; Iran; Rhinocerebral mucormycosis