title: [Interventional mitral valve replacement. Current status].
abstract: Approximately 30 % of patients suffering from severe valvular heart disease, such as mitral valve regurgitation are non-compliant to the gold standard of minimally invasive surgery, reconstruction or valve replacement. The number of these mostly old patients with severe comorbidities is increasing; therefore, transcatheter interventions have been developed to address an unmet clinical need and may be an alternative therapeutic option to the reference standard. Apart from the successful MitraClip therapy, alternative transcatheter reconstruction technologies are being developed. As with transcatheter aortic valve implantation (TAVI) procedures, the off-pump implantation of a valved stent into the mitral position mainly via a transapical approach will be of great benefit. Recently, the feasibility of transcatheter mitral valved stent implantation in high-risk patients has already been reported.
authors.affiliation: Klinik für Herz- und Gefäßchirurgie, Lehrstuhl für Experimentelle Herzchirurgie und Herzklappenersatz, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Deutschland. Georg.Lutter@uksh-kiel.de.
authors.forename: G
authors.initials: G
authors.lastname: Lutter
authors.affiliation: Klinik für Kardiologie und Angiologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Deutschland.
authors.forename: D
authors.initials: D
authors.lastname: Frank
mesh_terms: D006328:Cardiac Catheterization / Q000295:instrumentation / Q000639:trends*; D019317:Evidence-Based Medicine; D006350:Heart Valve Prosthesis / Q000639:trends*; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation / Q000639:trends*; D006801:Humans; D008943:Mitral Valve / Q000601:surgery*; D058386:Mitral Valve Annuloplasty / Q000295:instrumentation / Q000639:trends*; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D011474:Prosthesis Design / Q000639:trends; D016896:Treatment Outcome
keywords: Mitral stent; Mitral valve insufficiency; Off-pump; Transapical; Transcatheter