title: Case reports - When bronchial obstruction in the young adult is not asthma and inhalers do not help.
abstract: Localised bronchial obstruction is a rare differential diagnosis to asthma.
  
  
  
  We describe two younger patients treated unsuccessfully for asthma and eventually diagnosed with localised bronchoconstriction.
  
  
  
  Bronchoscopy revealed bronchoconstriction: Tracheobronchomalacia in case 1 and fixed obstruction in case 2.
  
  
  
  A systematic approach to the asthma patient with absent response to therapy facilitates rational use of therapeutic and diagnostic resources.
authors.affiliation: a Department of Internal Medicine , Unit of Pulmonary Medicine , Naestved Sygehus, Naestved , Denmark.|b Center for Neuropsychiatric Schizophrenia Research (CNSR), Mental Health Centre Glostrup , Glostrup , Denmark.
authors.forename: Anne
authors.initials: A
authors.lastname: Sigvard
authors.affiliation: a Department of Internal Medicine , Unit of Pulmonary Medicine , Naestved Sygehus, Naestved , Denmark.|c Institute for Regional Health Research, University of Southern Denmark , Odense , Denmark.
authors.forename: Uffe
authors.initials: U
authors.lastname: Bødtger
mesh_terms: D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy; D016084:Bronchoconstriction / Q000187:drug effects*; D005260:Female; D006801:Humans; D009330:Nebulizers and Vaporizers
keywords: Bronchial obstruction; asthma differential diagnostics; bronchoconstriction; bronchoscopy; bronchostenosis; tracheobronchomalacia