title: [EFFECT OF OVERWEIGHT AND OBESITY ON THE EQUILIBRIUM TIME, BUT NO IN THE TOTAL BODY WATER AND BODY COMPOSITION COMPARTMENTS IN WOMEN SUBJECTS OVER 60 YEARS OF AGE].
abstract: BACKGROUND
  aging and obesity cause changes in water exchange rate, which could affect the equilibrium time of deuterium oxide (2H2O).
  
  
  OBJECTIVE
  to assess the effect of overweight and obesity on the equilibrium time of the stable isotope deuterium in saliva samples of older adults.
  
  
  METHODS
  a sample of 18 women over 63 years with a body mass index (BMI) of 20.8 to 40.5 kg/m2 were included. A basal saliva sample was took and immediately a dose of 30 g of 2H2O was administered orally. Saliva samples at 2, 2.5, 3, 3.5 and 4 hours post-dose were taken. Deuterium in saliva samples were analyzed by Fourier Transform Infrared spectroscopy technique.
  
  
  RESULTS
  the average in equilibrium time (plateau) in women of normal BMI (18.5-24.9 kg/m2) was 3.6 ± 0.2 hours, which was statistically different to those obtained in the group with overweight (25-29.9 kg/m2) and obese (>30 kg/m2) of 2.9 ± 0.4 hours and 2.8 ± 0.4 hours, respectively (p0.05).
  
  
  CONCLUSIONS
  obesity had an effect on the equilibrium times; however, did not affect the calculation of total body water and body composition in this older women adult group.
authors.affiliation: Coordinación de Nutrición. Departamento de Nutrición y Metabolismo. Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C.. helio@ciad.mx.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Lizárraga-Cañedo
authors.affiliation: Coordinación de Nutrición. Departamento de Nutrición y Metabolismo. Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C.. helio@ciad.mx.
authors.forename: Alma
authors.initials: A
authors.lastname: Robles-Sardin
authors.affiliation: Laboratorio de Metabolismo Energético. Instituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile.. helio@ciad.mx.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Salazar
authors.affiliation: Coordinación de Nutrición. Departamento de Nutrición y Metabolismo. Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C.. helio@ciad.mx.
authors.forename: Heliodoro
authors.initials: H
authors.lastname: Alemán-Mateo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition; D015992:Body Mass Index; D001834:Body Water / Q000378:metabolism*; D017666:Deuterium Oxide / Q000378:metabolism; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D050177:Overweight / Q000378:metabolism*; D012463:Saliva / Q000737:chemistry
chemical_list: D017666:Deuterium Oxide