title: Optic disc morphology in unilateral branch retinal vein occlusion using spectral domain optical coherence tomography.
abstract: BACKGROUND
  The aim of this study was to evaluate the association between optic nerve head (ONH) parameters and branch retinal vein occlusion (BRVO) using spectral domain optical coherence tomography (SD-OCT).
  
  
  METHODS
  Both eyes of 40 patients with unilateral BRVO (mean age: 67.4 ± 11.4 years, male: female - 18:22) were enrolled in this study. Control group consisted of randomly selected single healthy eyes of 40 age and gender matched volunteers (mean age: 64.7 ± 15.4 years, male: female - 16:24). ONH parameters (including optic disc area, optic cup area, neuroretinal rim area, cup volume, rim volume, cup-disc area ratio, horizontal and vertical cup-disc ratio, average retinal nerve fiber layer) were measured by SD-OCT. Axial length (AL) of the eyes was measured by non-contact optical low coherence reflectometry. The ONH parameters of eyes with BRVO were compared with those of fellow eyes using mixed model, one-way between-groups analysis of covariance was conducted to compare the ONH parameters of affected and unaffected fellow eyes in BRVO patients with those of the control eyes keeping confounding factors, including AL, age and gender under control in the statistical analysis.
  
  
  RESULTS
  None of the investigated ONH parameters of affected BRVO eyes, unaffected fellow eyes and control eyes were statistically different after controlling for AL, age and gender.
  
  
  CONCLUSIONS
  Optic disc morphology might not be a potential anatomical predisposing factor for development of BRVO.
authors.affiliation: Department of Ophthalmology, Semmelweis University, 39 Mária Str., 1085, Budapest, Hungary. szigandi@gmail.com.
authors.forename: Andrea
authors.initials: A
authors.lastname: Szigeti
authors.affiliation: Department of Ophthalmology, Semmelweis University, 39 Mária Str., 1085, Budapest, Hungary. schneider.miklos@med.semmelweis-univ.hu.
authors.forename: Miklós
authors.initials: M
authors.lastname: Schneider
authors.affiliation: Department of Ophthalmology, Semmelweis University, 39 Mária Str., 1085, Budapest, Hungary. ecsedy@yahoo.co.uk.
authors.forename: Mónika
authors.initials: M
authors.lastname: Ecsedy
authors.affiliation: Department of Ophthalmology, Semmelweis University, 39 Mária Str., 1085, Budapest, Hungary. nagy.zoltan_zsolt@med.semmelweis-univ.hu.
authors.forename: Zoltán Zs
authors.initials: ZZ
authors.lastname: Nagy
authors.affiliation: Department of Ophthalmology, Semmelweis University, 39 Mária Str., 1085, Budapest, Hungary. zsrecsan@gmail.com.
authors.forename: Zsuzsanna
authors.initials: Z
authors.lastname: Récsán
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D011446:Prospective Studies; D012165:Retinal Ganglion Cells / Q000473:pathology; D012170:Retinal Vein Occlusion / Q000175:diagnosis*; D041623:Tomography, Optical Coherence