title: Fe-Catalyzed Olefin Hydroamination with Diazo Compounds for Hydrazone Synthesis.
abstract: A novel Fe-catalyzed olefin hydroamination with diazo compounds for accessing hydrazones has been developed. Diazo compounds are used as radical acceptors and can be trapped by the in situ generated alkyl radical toward C-N bond formation. The reaction conditions are mild, and the substrate scope is broad. Additionally, this hydroamination protocol is applicable for intramolecular reactions to construct diverse heterocycles.
authors.affiliation: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University , 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University , 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China.
authors.forename: Jifeng
authors.initials: J
authors.lastname: Qi
authors.affiliation: Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University , 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, China.
authors.forename: Sunliang
authors.initials: S
authors.lastname: Cui
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D005290:Ferric Compounds / Q000737:chemistry*; D006835:Hydrazones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D000475:Alkenes; D001391:Azo Compounds; D005290:Ferric Compounds; D006835:Hydrazones