title: Aspergillus Vertebral Osteomyelitis Complicating Pulmonary Granuloma in an Immunocompetent Adult.
abstract: OBJECTIVE
  The aim of this report is to describe a case with Aspergillus vertebral osteomyelitis complicating pulmonary granuloma in an immunocompetent adult.
  
  
  METHODS
  A 53-year-old male patient was found to have lesions on lumbar vertebra 5 months after thoracoscopic resection of pulmonary granuloma that lacked a definite etiology. Three operations on the lumbar lesions were performed successively; however, an Aspergillus infection was not confirmed until hyphae were clearly detected at the last surgery. The patient was treated with voriconazole and recovered well.
  
  
  CONCLUSIONS
  This case shows that simultaneous occurrence of granulomatous nodules in the lung and vertebral lesions should raise suspicion of aspergillosis, even in immunocompetent patients.
authors.affiliation: Department of Respiratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Li
authors.forename: Yanyi
authors.initials: Y
authors.lastname: Cen
authors.forename: Yuwen
authors.initials: Y
authors.lastname: Luo
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhu
authors.forename: Shaoxiong
authors.initials: S
authors.lastname: Min
authors.forename: Xin
authors.initials: X
authors.lastname: Chen
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications*; D006099:Granuloma / Q000150:complications*; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology*; D008171:Lung Diseases / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000150:complications* / Q000382:microbiology
chemical_list: D000935:Antifungal Agents