title: Molecularly imprinted solid phase extraction in a syringe filter for determination of triazine herbicides in Radix Paeoniae Alba by ultra-fast liquid chromatography.
abstract: A novel, cost-effective and simple solid phase extraction (SPE) method, by using a syringe connected with a nylon membrane filter as the adsorbent container, was developed for the extraction of triazine herbicides from Radix Paeoniae Alba (RPA) samples. The selective molecularly imprinted polymers (MIPs) synthesized with the template of atrazine were employed as the adsorbents for the enrichment and purification of analytes. The extraction parameters, including the volume and type of loading solvent, the type of washing solvent and eluting solvent, were investigated. Under the optimized conditions, the final extracts were analyzed by ultra-fast liquid chromatography (UFLC). Recoveries of the developed method range from 92.4% to 107.3% with intra- and inter-day relative standard deviations (RSDs) lower than 8.2%. The calibration curve is linear in the concentration range of 0.005-2.4 µg g(-1) for desmetryn, atrazine and terbumeton, and 0.005-1.5 µg g(-1) for dimethametryn and dipropetryn, with the correlation coefficient (R(2)) higher than 0.9995. The limits of detection (LODs) of five triazine herbicides are in the range of 0.09-0.39 ng g(-1), which are lower than the maximum residue levels (MRLs) established by various official organizations. Analytical results of three real Radix Paeoniae Alba samples indicate that the proposed method is cost-effective and easy-to-use than other routine pretreatment methods.
authors.affiliation: College of Chemistry, Jilin University, Qianjin Street 2699, Changchun 130012, PR China.
authors.forename: Xinpei
authors.initials: X
authors.lastname: Li
authors.affiliation: College of Chemistry, Jilin University, Qianjin Street 2699, Changchun 130012, PR China.
authors.forename: Yuanpeng
authors.initials: Y
authors.lastname: Wang
authors.affiliation: College of Chemistry, Jilin University, Qianjin Street 2699, Changchun 130012, PR China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Sun
authors.affiliation: College of Chemistry, Jilin University, Qianjin Street 2699, Changchun 130012, PR China.
authors.forename: Bo
authors.initials: B
authors.lastname: Xu
authors.affiliation: College of Instrumentation & Electrical Engineering, Jilin University, Ximinzhu Street 938, Changchun 130061, PR China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Yu
authors.affiliation: College of Chemistry, Jilin University, Qianjin Street 2699, Changchun 130012, PR China. Electronic address: wxh.anal@gmail.com.
authors.forename: Xinghua
authors.initials: X
authors.lastname: Wang
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods; D006540:Herbicides / Q000032:analysis*; D054802:Molecular Imprinting / Q000295:instrumentation / Q000379:methods*; D029596:Paeonia / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D013594:Syringes; D014227:Triazines / Q000032:analysis*
chemical_list: D006540:Herbicides; D010936:Plant Extracts; D014227:Triazines
keywords: Molecularly imprinted polymer (MIP); Radix Paeoniae Alba (RPA); Solid phase extraction (SPE); Triazine herbicides; Ultra-fast liquid chromatography (UFLC)