title: Follicular Thyroid Adenoma Showing Avid Uptake on 68Ga PSMA-HBED-CC PET/CT.
abstract: 68Ga-prostate-specific membrane antigen (PSMA) PET/CT imaging is a relatively new imaging technique used to evaluate the extent of disease in prostate carcinoma. Various other neoplasms may also express PSMA and show uptake on PSMA PET/CT scan. We report a case of a 62-year-old man who had a PSMA PET/CT scan for restaging of prostate carcinoma. A PSMA-avid thyroid lesion was identified, and subsequent tissue sampling confirmed the diagnosis of follicular thyroid adenoma. It is important to be aware of this possibility to avoid scan misinterpretation. Tissue biopsy of PSMA-avid thyroid lesions should be considered to exclude a primary thyroid neoplasm.
authors.affiliation: From the *Department of Nuclear Medicine, Royal North Shore Hospital; †Genesis Cancer Care, Mater Hospital; and ‡The University of Sydney, Sydney, Australia.
authors.forename: Gowri L
authors.initials: GL
authors.lastname: Kanthan
authors.forename: James
authors.initials: J
authors.lastname: Drummond
authors.forename: Geoff Paul
authors.initials: GP
authors.lastname: Schembri
authors.forename: Michael A
authors.initials: MA
authors.lastname: Izard
authors.forename: Edward
authors.initials: E
authors.lastname: Hsiao
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging*; D002277:Carcinoma / Q000000981:diagnostic imaging; D004492:Edetic Acid / Q000031:analogs & derivatives; D005709:Gallium Isotopes; D005710:Gallium Radioisotopes; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D009842:Oligopeptides; D009942:Organometallic Compounds; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals; D013961:Thyroid Gland / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
chemical_list: D005709:Gallium Isotopes; D005710:Gallium Radioisotopes; D009842:Oligopeptides; D009942:Organometallic Compounds; D019275:Radiopharmaceuticals; C000718244:gallium 68 PSMA-11; D004492:Edetic Acid