title: [Analysis of the characteristic of pharyngeal paraesthesia patients by high resolution manometry].
abstract: OBJECTIVE
  To discuss the pressure changing characteristics of upper esophageal sphincter (UES), lower esophageal sphincter (LES) and the esophagus kinetic characteristics of pharyngeal paraesthesia patients.
  
  
  METHODS
  To take high resolution manometry in 44 cases of pharyngeal paraesthesia patients and 23 normal subjects separately. According to the RSI score,the 44 patients were divided into group A (the group without reflux, RSI < 13, n = 25) and group B (the group with reflux, RSI ≥ 13, n = 19).
  
  
  RESULTS
  The UES average resting pressure and average residual pressure of patients group were higher than the control group (P < 0.05); The UES average resting pressure and average residual pressure of group B were higher than group A (P < 0.05); The LES average resting pressure and average residual pressure of group B were lower than group A and the control group (P < 0.05); The comparison of LES average resting pressure and average residual pressure between group A and the control group was not statistically significant (P > 0.05). The esophagus DCI of group B was lower than that of group A and control group (P < 0.05). The esophagus DCI comparison between group A and control group was not statistically significant (P > 0.05).
  
  
  CONCLUSIONS
  The pharyngeal paresthesia symptoms of'patients was associated with the increasing of UES pressure. The pharyngeal paresthesia symptoms of group with reflux was related to low pressure of LES and high pressure of UES. The last part of esophagus of group with reflux had obstacles in powers, which weaken the peristalsis and declined the ability to clear the bolus and gastric reflux material.
authors.forename: Yun
authors.initials: Y
authors.lastname: Gu
authors.forename: Wei
authors.initials: W
authors.lastname: Qian
mesh_terms: D016022:Case-Control Studies; D049630:Esophageal Sphincter, Lower / Q000503:physiopathology; D049631:Esophageal Sphincter, Upper / Q000503:physiopathology; D005764:Gastroesophageal Reflux / Q000503:physiopathology; D006801:Humans; D008365:Manometry; D010292:Paresthesia / Q000175:diagnosis / Q000473:pathology*; D010528:Peristalsis; D010614:Pharynx / Q000503:physiopathology*; D011312:Pressure