title: Human Microbiome and its Association With Health and Diseases.
abstract: Human microbiota are distinct communities of microorganisms that resides at different body niches. Exploration of the human microbiome has become a reality due to the availability of powerful metagenomics and metatranscriptomic analysis technologies. Recent advances in sequencing and bioinformatics over the past decade help provide a deep insight into the nature of the host-microbial interactions and identification of potential deriver genes and pathways associated with human health, well-being, and predisposition to different diseases. In the present review, we outline recent studies devoted to elucidate the possible link between the microbiota and various type of diseases. The present review also highlights the potential utilization of microbiota as a potential therapeutic option to treat a wide array of human diseases. J. Cell. Physiol. 231: 1688-1694, 2016. © 2015 Wiley Periodicals, Inc.
authors.affiliation: Biomedical Research Center, Qatar University, Doha, Qatar.|Department of Health Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar.
authors.forename: Asmaa A
authors.initials: AA
authors.lastname: Althani
authors.affiliation: Biomedical Research Center, Qatar University, Doha, Qatar.
authors.forename: Hany E
authors.initials: HE
authors.lastname: Marei
authors.affiliation: Biomedical Research Center, Qatar University, Doha, Qatar.
authors.forename: Wedad S
authors.initials: WS
authors.lastname: Hamdi
authors.affiliation: Department of Health Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar.
authors.forename: Gheyath K
authors.initials: GK
authors.lastname: Nasrallah
authors.affiliation: Biomedical Research Center, Qatar University, Doha, Qatar.
authors.forename: Mohamed E
authors.initials: ME
authors.lastname: El Zowalaty
authors.affiliation: Infectious Disease Unit, Division of Translational Medicine, SIDRA Medical and Research Center, Qatar.
authors.forename: Souhaila
authors.initials: S
authors.lastname: Al Khodor
authors.affiliation: Department of Health Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar.
authors.forename: Maha
authors.initials: M
authors.lastname: Al-Asmakh
authors.affiliation: Department of Health Sciences, College of Arts and Sciences, Qatar University, Doha, Qatar.
authors.forename: Hassan
authors.initials: H
authors.lastname: Abdel-Aziz
authors.affiliation: CNR-Institute of Translational Pharmacology, Via Fosso del Cavaliere, Roma, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Cenciarelli
mesh_terms: D001419:Bacteria / Q000145:classification / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity; D004066:Digestive System Diseases / Q000382:microbiology / Q000821:virology; D004198:Disease Susceptibility; D064806:Dysbiosis / Q000382:microbiology / Q000821:virology; D005658:Fungi / Q000145:classification / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity; D006304:Health Status; D054884:Host-Pathogen Interactions; D006801:Humans; D008659:Metabolic Diseases / Q000382:microbiology / Q000821:virology; D064307:Microbiota; D019636:Neurodegenerative Diseases / Q000382:microbiology / Q000821:virology; D012307:Risk Factors; D014780:Viruses / Q000145:classification / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity