title: An economical synthesis of substituted quinoline-2-carboxylates through the potassium persulfate-mediated cross-dehydrogenative coupling of N-aryl glycine derivatives with olefins.
abstract: A practical and economical K2S2O8-mediated oxidative cross-dehydrogenative coupling of N-aryl glycine derivatives with olefins has been established, affording structurally diverse quinoline-2-carboxylates in good to high efficiency. The low cost, negligible toxicity, and ease of handling of K2S2O8 combined with the absence of hazardous byproducts and the easy workup consisting of simple filtration are attractive based on economic and environmental factors.
authors.affiliation: School of Ocean, Shandong University, Weihai 264209, China. xiali@sdu.edu.cn.
authors.forename: Guoliang
authors.initials: G
authors.lastname: Liu
authors.forename: Jiarui
authors.initials: J
authors.lastname: Qian
authors.forename: Jing
authors.initials: J
authors.lastname: Hua
authors.forename: Feng
authors.initials: F
authors.lastname: Cai
authors.forename: Xia
authors.initials: X
authors.lastname: Li
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D005998:Glycine / Q000737:chemistry*; D006865:Hydrogenation; D015394:Molecular Structure; D017680:Potassium Compounds / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013431:Sulfates / Q000737:chemistry*
chemical_list: D000475:Alkenes; D017680:Potassium Compounds; D011804:Quinolines; D013431:Sulfates; C059924:quinoline-4-carboxylic acid; C009007:potassium persulfate; D005998:Glycine