title: Keratocystic Odontogenic Tumour with Extraosseal Spread: Evaluation of the Effect Carnoy's Solution.
abstract: Keratocystic odontogenic tumour is relatively rare benign tumour. It is characterized by its fast aggressive growth and high risk of recurrence. Treatment is always surgical: conservative (enucleation, marsupialization) or aggressive (enucleation followed by application of Carnoy's solution, cryotherapy; peripheral ostectomy or en block resection of the jaw). Authors analysed retrospectively 22 patients who fulfilled inclusion criteria, i.e. had odontogenic keratocystic tumour of mandible, wherein antero-posterior dimension was at least 30 mm, and the tumour penetrated into the surrounding soft tissues. All patients underwent tumour enucleation, in 11 patients Carnoy's solution was given into the bone cavity after enucleation. The recurrence rate in the evaluation at least 36 months after surgery was both patient groups the same: 45.4%.
authors.affiliation: Department of Dental Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic. Jitka.Levorova@seznam.cz.
authors.forename: Jitka
authors.initials: J
authors.lastname: Levorová
authors.affiliation: Department of Dental Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic.
authors.forename: Vladimír
authors.initials: V
authors.lastname: Machoň
authors.affiliation: Faculty of Electrical Engineering, Czech Technical University in Prague, Prague, Czech Republic.
authors.forename: Pavel
authors.initials: P
authors.lastname: Grill
authors.affiliation: Ruzinov Hospital, Bratislava, Slovakia.
authors.forename: Dušan
authors.initials: D
authors.lastname: Hirjak
authors.affiliation: Department of Dental Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic.
authors.forename: René
authors.initials: R
authors.lastname: Foltán
mesh_terms: D019342:Acetic Acid / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002725:Chloroform / Q000627:therapeutic use*; D000431:Ethanol / Q000627:therapeutic use*; D005260:Female; D005404:Fixatives; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D009808:Odontogenic Tumors / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: C033474:Carnoy's solution; D005404:Fixatives; D000431:Ethanol; D002725:Chloroform; D019342:Acetic Acid
keywords: Carnoy’s solution; Enucleation; Keratocystic odontogenic tumour; Recurrence