title: Isoprostanes - A novel major group of oxidative stress markers.
abstract: Isoprostanes are a recently discovered group of prostaglandin isomers. Results of previous studies suggest that they can be used as oxidative stress markers, because in a number of cardiovascular, pulmonary and neurological diseases their levels in biological samples considerably increase. It has been found that people suffering from diabetes, obesity, homozygous familial hypercholesterolemia, moderate hypercholesterolemia, and smokers have higher levels of isoprostanes in urine. The same refers to patients with asthma, Alzheimer disease and Down syndrome. This paper reviews the results of relevant studies.
authors.affiliation: Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Toxicology and Carcinogenesis). czerskamar@gmail.com.
authors.forename: Marta
authors.initials: M
authors.lastname: Czerska
authors.affiliation: Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Toxicology and Carcinogenesis). marek.zielinski78@gmail.com.
authors.forename: Marek
authors.initials: M
authors.lastname: Zieliński
authors.affiliation: Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Toxicology and Carcinogenesis). jola@imp.lodz.pl.
authors.forename: Jolanta
authors.initials: J
authors.lastname: Gromadzińska
mesh_terms: D015415:Biomarkers / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000378:metabolism*; D006801:Humans; D028421:Isoprostanes / Q000378:metabolism*; D018384:Oxidative Stress
chemical_list: D015415:Biomarkers; D028421:Isoprostanes
keywords: asbestosis; cardiovascular; isoprostanes; neurological; oxidative stress biomarkers; pulmonary