title: Stroke. Support for IV tPA in ischaemic stroke in elderly people.
abstract: In Europe, use of intravenous tissue plasminogen activator (tPA) in patients older than 80 years is discouraged because these patients have been excluded from certain past clinical trials. A new retrospective, observational study shows that tPA can substantially improve functional outcome after ischaemic stroke in patients aged 80–89 years.
authors.affiliation: Stroke Center &Department of Neurology, Kings County Hospital Center &The State University of New York Downstate Medical Center, 451 Clarkson Avenue, Brooklyn, New York, NY-11203, USA.
authors.forename: Susan W
authors.initials: SW
authors.lastname: Law
authors.affiliation: Stroke Center &Department of Neurology, Kings County Hospital Center &The State University of New York Downstate Medical Center, 451 Clarkson Avenue, Brooklyn, New York, NY-11203, USA.
authors.forename: Steven R
authors.initials: SR
authors.lastname: Levine
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000188:drug therapy; D005060:Europe; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D012189:Retrospective Studies; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents