title: Polyarthritis and membranoproliferative glomerulonephritis as paraneoplastic manifestation of Hodgkin's lymphoma: A case report and literature review.
abstract: Paraneoplastic syndromes can be presented in multiple ways, which include endocrinological, hematologic, rheumatologic and nephrologic manifestations. While most of the publications described solid tumors as responsible for these manifestations, hematologic neoplasms are important cause to consider as part of the differential diagnosis. We report the case of a 46 year-old man with seronegative symmetric polyarthritis of large and small joints associated with membranoproliferative glomerulonephritis with deposits of immune complexes and acute impairment of renal function, as part of a paraneoplastic syndrome secondary of a classical Hodgkin lymphoma with bone marrow invasion, which reversed completely with chemotherapy treatment.
authors.affiliation: Sección de Reumotalogía, Hospital del Salvador, Universidad de Chile, Santiago, Chile. Electronic address: danerlij@gmail.com.
authors.forename: Daniel
authors.initials: D
authors.lastname: Erlij
authors.affiliation: Servicio de Medicina, Hospital del Salvador, Universidad de Chile, Santiago, Chile.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Calderón
authors.affiliation: Sección de Reumotalogía, Hospital del Salvador, Universidad de Chile, Santiago, Chile.
authors.forename: Angela
authors.initials: A
authors.lastname: Rivera
authors.affiliation: Servicio de Medicina Interna, Hospital del Salvador, Universidad de Chile, Santiago, Chile.
authors.forename: Cristián
authors.initials: C
authors.lastname: Mella
authors.affiliation: Sección de Hematología, Hospital del Salvador, Santiago, Chile.
authors.forename: Ximena
authors.initials: X
authors.lastname: Valladares
authors.affiliation: Sección de Nefrología, Hospital del Salvador, Universidad de Chile, Santiago, Chile.
authors.forename: Emilio
authors.initials: E
authors.lastname: Roessler
authors.affiliation: Servicio de Anatomía Patológica, Hospital del Salvador, Santiago, Chile.
authors.forename: María Teresa
authors.initials: MT
authors.lastname: Rivera
authors.affiliation: Servicio de Anatomía Patológica, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Méndez
mesh_terms: D001168:Arthritis / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D015432:Glomerulonephritis, Membranoproliferative / Q000175:diagnosis / Q000209:etiology*; D006689:Hodgkin Disease / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000209:etiology*
keywords: Glomerulonefritis membranoproliferativa; Hodgkin lymphoma; Linfoma de Hodgkin; Membranoproliferative glomerulonephritis; Paraneoplastic syndrome; Poliartritis; Polyarthritis; Síndrome paraneoplásico