title: Drug Therapy for Behavioral and Psychological Symptoms of Dementia.
abstract: Dementia, which can be induced by diverse factors, is a clinical syndrome characterized by the decline of cognitive function. Behavioral and psychological symptoms of dementia (BPSD) include depression, agitation, and aggression. Dementia causes a heavy burden on patients and their caregivers. Patients with BPSD should be assessed comprehensively by practitioners and offered appropriate non-pharmacologic and pharmacologic therapy. Nonpharmacologic therapy has been recommended as the basal treatment for BPSD; however, pharmacologic therapy is required under many situations. Medications, including antipsychotic agents, antidepressants, sedative and hypnotic agents, mood stabilizers, cholinesterase inhibitors, and amantadine, are extensively used in clinical practice. We have reviewed the progression of pharmacologic therapy for BPSD.
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.forename: Ting-Yi
authors.initials: TY
authors.lastname: Feng
authors.forename: Shilin
authors.initials: S
authors.lastname: Yang
authors.forename: Maurice
authors.initials: M
authors.lastname: Preter
authors.forename: Jiang-Ning
authors.initials: JN
authors.lastname: Zhou
authors.affiliation: Department of Neurology, Shanghai First People's Hospital, Shanghai Jiao-Tong University, China, 200080. x_p_wang@sjtu.edu.cn.
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Wang
mesh_terms: D000547:Amantadine / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001526:Behavioral Symptoms / Q000188:drug therapy; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D003704:Dementia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008297:Male; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D002800:Cholinesterase Inhibitors; D006993:Hypnotics and Sedatives; D000547:Amantadine