title: Bisphenol A (BPA) in food contact materials - new scientific opinion from EFSA regarding public health risk.
abstract: The wide use of bisphenol A (BPA) as a monomer in plastics manufacture or epoxy resins intended for food contact materials (FCM) has triggered numerous concerns due to toxicological findings indicating possible endocrine disrupting properties. This article traces the evolution of the scientific opinions since 1986 when the Tolerable Daily Intake (TDI) for BPA and its specific migration limit (SML) from plastic FCM into food were proposed for the first time by the Scientific Committee for Food (SCF). Resent extensive scientific studies concerning refined data on toxicity and exposure to BPA from food and non-food sources (eg. dust, cosmetics, thermal paper), including the most vulnerable groups of population, allowed the European Food Safety Authority (EFSA) to reduce the TDI of BPA from previously 50 µg/kg bw/day to now 4 µg/kg bw/day. EFSA's latest scientific opinion published in 2015 concludes that basing on the current estimations of total exposure to BPA from dietary and non-dietary sources for infants, children and adolescents is below the temporary TDI of 4 μg/kg bw/day. EFSA has also underlined that BPA poses no health risk at the estimated exposure levels of any population age group, including unborn children and the elderly. However, EFSA has indicated that some data on exposure and toxicological effects still require clarifications.
authors.affiliation: National Institute of Public Health - National Institute of Hygiene, Chocimska street 24, 00-791 Warsaw, Poland.
authors.forename: Kazimiera
authors.initials: K
authors.lastname: Ćwiek-Ludwicka
mesh_terms: D001559:Benzhydryl Compounds / Q000633:toxicity*; D004781:Environmental Exposure / Q000009:adverse effects*; D004784:Environmental Monitoring; D005060:Europe; D005506:Food Contamination / Q000517:prevention & control*; D018857:Food Packaging / Q000592:standards; D015386:Hazardous Substances / Q000633:toxicity*; D006801:Humans; D008452:Maximum Allowable Concentration; D010636:Phenols / Q000633:toxicity*; D011044:Poland; D011634:Public Health / Q000592:standards*; D018570:Risk Assessment; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D015386:Hazardous Substances; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds