title: Intraoperative mechanical ventilation strategies to prevent postoperative pulmonary complications in patients with pulmonary and extrapulmonary comorbidities.
abstract: A variety of patient characteristics and comorbidities have been identified, which increase the risk of postoperative pulmonary complications (PPCs), including smoking, age, chronic obstructive pulmonary disease, pulmonary hypertension, obstructive sleep apnea, cardiac and neurologic diseases as well as critical illness. In contrast to the variety of conditions, evidence for specific intraoperative ventilation strategies to reduce PPC is very limited for most comorbidities. Here, we provide an overview of and discuss possible implications for the intraoperative ventilatory management of patients with comorbidities.
authors.affiliation: Department of Anesthesiology, Duesseldorf University Hospital, Heinrich-Heine University, Moorenstr. 5, 40225 Duesseldorf, Germany. Electronic address: tanja.treschan@med.uni-duesseldorf.de.
authors.forename: Tanja A
authors.initials: TA
authors.lastname: Treschan
authors.affiliation: Divisão de Anestesiologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 155, 8th Floor, 05403-000 São Paulo, SP, Brazil. Electronic address: malbouisson@gmail.com.
authors.forename: Luiz Marcelo
authors.initials: LM
authors.lastname: Malbouisson
authors.affiliation: Department of Anaesthesiology, Marienhospital Osnabrück, Bischofsstraße 1, 49074 Osnabrück, Germany. Electronic address: martin.beiderlinden@mho.de.
authors.forename: Martin
authors.initials: M
authors.lastname: Beiderlinden
mesh_terms: D000818:Animals; D015897:Comorbidity; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D011183:Postoperative Complications / Q000517:prevention & control*; D012121:Respiration, Artificial / Q000009:adverse effects / Q000379:methods*; D012307:Risk Factors; D055397:Ventilator-Induced Lung Injury / Q000517:prevention & control*
keywords: artificial respiration; mechanical ventilation; protective ventilation; pulmonary complications; ventilator-induced lung injury