title: Venous flow volume measured by duplex ultrasound can be used as an indicator of impaired tissue perfusion in patients with peripheral arterial disease.
abstract: OBJECTIVE
  In this study, we aimed to investigate the arterial and venous flow volume rate (FV) in order to determine the tissue perfusion using duplex ultrasonography (DU). We hypothesized that FV provides reliable information regarding tissue perfusion in patients with peripheral arterial disease (PAD).
  
  
  METHODS
  The study comprised 38 patients (72 legs) with PAD. In all patients, common femoral, popliteal, anterior tibial, posterior tibial arteries and veins were examined with DU. Measurements were obtained in the supine position with 15 cm elevation of the foot to neutralise central venous pressure. The diameter, blood flow velocity, and FV of arteries and veins were measured for each patient.
  
  
  RESULTS
  The FV of the common femoral artery and vein (p = 0.001), popliteal artery and vein (p=0.003), and posterior tibial artery and vein (p = 0.008) had statistically significant differences. However, there was no statistically significant difference between the FV of the anterior tibial vein and artery (p = 0.408). The mean FV values of all veins were significantly lower than those of homonymous arteries in patients with PAD.
  
  
  CONCLUSIONS
  Our study showed that venous FV measured by DU can be used as an indicator of impaired tissue perfusion in patients with PAD.
authors.affiliation: Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Radiology, Izmir, Turkey. doktorozlemtugce@gmail.com.
authors.forename: Tugce Ozlem
authors.initials: TO
authors.lastname: Kalayci
authors.affiliation: Gaziosmanpasa University, Medical School, Department of Radiology, Tokat, Izmir, Turkey.
authors.forename: Fitnet
authors.initials: F
authors.lastname: Sonmezgoz
authors.affiliation: Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Radiology, Izmir, Turkey.
authors.forename: Melda
authors.initials: M
authors.lastname: Apaydin
authors.affiliation: Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Radiology, Izmir, Turkey.
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Inci
authors.affiliation: Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Radiology, Izmir, Turkey.
authors.forename: Ali Firat
authors.initials: AF
authors.lastname: Sarp
authors.affiliation: Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Radiology, Izmir, Turkey.
authors.forename: Bilge
authors.initials: B
authors.lastname: Birlik
authors.affiliation: Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Radiology, Izmir, Turkey.
authors.forename: Muhsin Engin
authors.initials: ME
authors.lastname: Uluç
authors.affiliation: Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Radiology, Izmir, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Oyar
authors.affiliation: Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Cardiovascular Surgery, İzmir, Turkey.
authors.forename: Mert
authors.initials: M
authors.lastname: Kestelli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity; D001810:Blood Volume; D001811:Blood Volume Determination / Q000379:methods; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods*; D014680:Veins / Q000000981:diagnostic imaging* / Q000503:physiopathology*