title: Splenic liposarcoma in dogs: 13 cases (2002-2012).
abstract: OBJECTIVE
  To describe the clinical signs, diagnostic findings, surgical management, and outcome in dogs with splenic liposarcoma.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  13 client-owned dogs with splenic liposarcoma.
  
  
  METHODS
  Medical and pathology records of dogs with a histopathologic diagnosis of splenic liposarcoma from 2002 to 2012 were reviewed for the following data: clinical signs, CBC, biochemical profile, thoracic and abdominal imaging, surgical management, histologic grade, and outcome (local recurrence, distant metastasis, and survival time). Telephone interviews were conducted with referring veterinarians.
  
  
  RESULTS
  The median survival time (MST) was 623 days (range, 1 to 1,283 days). In 5 dogs that died of splenic liposarcoma, survival times ranged from 42 to 369 days. Metastasis at the time of surgery was a negative prognostic indicator: the MST was 45 days for dogs with metastasis and 767 days for dogs without metastasis. Dogs with grade 1 splenic liposarcoma had a significantly greater MST (1,009 days), compared with dogs with grade 2 or 3 splenic liposarcoma (MST, 206 and 74 days, respectively).
  
  
  CONCLUSIONS
  Results confirmed that splenic liposarcoma is a rare differential diagnosis in dogs with a splenic mass. Survival time was influenced by preoperative clinical stage and histologic grade.
authors.forename: Krista L A
authors.initials: KL
authors.lastname: Gower
authors.forename: Julius M
authors.initials: JM
authors.lastname: Liptak
authors.forename: William T N
authors.initials: WT
authors.lastname: Culp
authors.forename: Lina
authors.initials: L
authors.lastname: Bravo
authors.forename: Barbara
authors.initials: B
authors.lastname: Powers
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Withrow
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D008080:Liposarcoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D008297:Male; D012189:Retrospective Studies; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D016896:Treatment Outcome