title: Incidence of Successful Pregnancy After Weight Loss Interventions in Infertile Women: a Systematic Review and Meta-Analysis of the Literature.
abstract: Little is known about the impact of weight loss interventions on pregnancy rate. A systematic review with meta-analysis of literature has been performed to evaluate the incidence of successful pregnancy after bariatric interventions in infertile women. By pooling together data from 589 infertile obese women, we have been able to provide an aggregate estimation of successful pregnancy after weight loss interventions. Our results showed an impressive high incidence (58%) of infertile women who become spontaneously pregnant after surgery. Based on our results, bariatric interventions could be included in the treatment of obesity-related infertility. However, the results must be interpreted with caution owning to the quality of the data provided by included studies. Further ad hoc studies are needed to validate the effectiveness of bariatric interventions on reproductive function.
authors.affiliation: Department of Advanced Biomedical Science Surgery Unit, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy. milone.marco.md@gmail.com.
authors.forename: Marco
authors.initials: M
authors.lastname: Milone
authors.affiliation: Department of Advanced Biomedical Science Surgery Unit, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: De Placido
authors.affiliation: Department of Advanced Biomedical Science Surgery Unit, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Musella
authors.affiliation: Department of Advanced Biomedical Science Surgery Unit, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.
authors.forename: Loredana Maria
authors.initials: LM
authors.lastname: Sosa Fernandez
authors.affiliation: Department of Advanced Biomedical Science Surgery Unit, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.
authors.forename: Laura Virginia
authors.initials: LV
authors.lastname: Sosa Fernandez
authors.affiliation: Department of Advanced Biomedical Science Surgery Unit, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Campana
authors.affiliation: Department of Advanced Biomedical Science Surgery Unit, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.
authors.forename: Matteo Nicola Dario
authors.initials: MN
authors.lastname: Di Minno
authors.affiliation: Department of Advanced Biomedical Science Surgery Unit, University of Naples "Federico II", Via Pansini 5, 80131, Naples, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Milone
mesh_terms: D000328:Adult; D050110:Bariatric Surgery; D005260:Female; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000209:etiology / Q000601:surgery*; D007558:Italy / Q000453:epidemiology; D009765:Obesity / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D011247:Pregnancy / Q000706:statistics & numerical data*; D018873:Pregnancy Rate; D015431:Weight Loss
keywords: BMI; Bariatric; Fertility; Infertility; Obesity