title: 5th International ACC Symposium: An Outlook to Current and Future Research on the Biology of Adrenocortical Carcinoma: Diagnostic and Therapeutic Applications.
abstract: Groundbreaking progress has been recently made in elucidating the signaling pathways that are altered in adrenocortical carcinoma (ACC), an endocrine malignancy that still has an unfavorable prognosis, and in understanding its genomic structure. These advances need now to be translated to create cellular and animal models more relevant to human disease in order to develop new and more effective diagnostic procedures and targeted therapies against this deadly malignancy.
authors.affiliation: Institut de Pharmacologie Moléculaire et Cellulaire CNRS, 660 route des Lucioles, 06560, Valbonne, France. ninino@ipmc.cnrs.fr.|NEOGENEX CNRS International Associated Laboratory, Valbonne, France. ninino@ipmc.cnrs.fr.|Université de Nice-Sophia Antipolis, Nice, France. ninino@ipmc.cnrs.fr.
authors.forename: Enzo
authors.initials: E
authors.lastname: Lalli
authors.affiliation: Department of Pathology, Tohoku University School of Medicine, 2-1 Seiryo-machi, Aoba-ku Sendai, 980-8575, Japan. hsasano@patholo2.med.tohoku.ac.jp.
authors.forename: Hironobu
authors.initials: H
authors.lastname: Sasano
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis* / Q000188:drug therapy* / Q000235:genetics; D018268:Adrenocortical Carcinoma / Q000175:diagnosis* / Q000188:drug therapy* / Q000235:genetics; D000818:Animals; D014408:Biomarkers, Tumor / Q000235:genetics*; D002986:Clinical Trials as Topic; D003226:Congresses as Topic; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D035683:MicroRNAs / Q000235:genetics; D015398:Signal Transduction; D002785:Sterol O-Acyltransferase / Q000037:antagonists & inhibitors
chemical_list: D014408:Biomarkers, Tumor; D004791:Enzyme Inhibitors; D035683:MicroRNAs; D002785:Sterol O-Acyltransferase; C493492:sterol O-acyltransferase 1