title: Fluorine-18 patents (2009-2015). Part 1: novel radiotracers.
abstract: The most commonly utilized PET radionuclide is fluorine-18 ((18)F) because of its convenient half-life and excellent imaging properties. In this review, we present the first analysis of patents issued for radiotracers labeled with fluorine-18 (between 2009 and 2015), and provide perspective on current trends and future directions in PET radiotracer development.
authors.affiliation: Department of Radiology, University of Michigan Medical School, 1301 Catherine St., Ann Arbor, MI 48109, USA.
authors.forename: Allen F
authors.initials: AF
authors.lastname: Brooks
authors.affiliation: Department of Medicinal Chemistry, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
authors.forename: Lindsey R
authors.initials: LR
authors.lastname: Drake
authors.affiliation: Department of Medicinal Chemistry, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
authors.forename: Megan N
authors.initials: MN
authors.lastname: Stewart
authors.affiliation: Department of Radiology, University of Michigan Medical School, 1301 Catherine St., Ann Arbor, MI 48109, USA.
authors.forename: Brian P
authors.initials: BP
authors.lastname: Cary
authors.affiliation: Department of Radiology, University of Michigan Medical School, 1301 Catherine St., Ann Arbor, MI 48109, USA.
authors.forename: Isaac M
authors.initials: IM
authors.lastname: Jackson
authors.affiliation: Department of Radiology, University of Michigan Medical School, 1301 Catherine St., Ann Arbor, MI 48109, USA.
authors.forename: Dale
authors.initials: D
authors.lastname: Mallette
authors.affiliation: Department of Radiology, University of Michigan Medical School, 1301 Catherine St., Ann Arbor, MI 48109, USA.
authors.forename: Andrew V
authors.initials: AV
authors.lastname: Mossine
authors.affiliation: Department of Radiology, University of Michigan Medical School, 1301 Catherine St., Ann Arbor, MI 48109, USA.|Department of Medicinal Chemistry, University of Michigan, 428 Church St., Ann Arbor, MI 48109, USA.
authors.forename: Peter J H
authors.initials: PJ
authors.lastname: Scott
mesh_terms: D000818:Animals; D005462:Fluorine Radioisotopes; D006331:Heart Diseases / Q000000981:diagnostic imaging; D006801:Humans; D009369:Neoplasms / Q000000981:diagnostic imaging; D009422:Nervous System Diseases / Q000000981:diagnostic imaging; D059906:Neuroimaging; D010330:Patents as Topic; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
chemical_list: D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals