title: Upconversion nanosensor for sensitive fluorescence detection of Sudan I-IV based on inner filter effect.
abstract: Sudan dyes are banned as food additives due to the carcinogenicity of their metabolites in the human body. Therefore, it is of great significance for sensitive detection of Sudan dyes. This paper reports a novel nanosensor for Sudan dyes detection based on fluorescence (FL) quenching of hexadecyl trimethyl ammonium bromide (CTAB) stabilized upconversion nanoparticles (UCNPs) through the inner filter effect (IFE). In the presence of Sudan I-IV, the fluorescence emission of UCNPs was effectively quenched due to the absorption bands of Sudan I-IV largely covered the emission bands of UCNPs. Under the optimized conditions, the FL was quenched with Sudan concentration over the range of 0.05-40, 0.01-20, 0.01-40 and 0.05-40 μg/mL for Sudan I-IV, respectively. The corresponding limit of detection is 15.1, 2.83, 3.52 and 16.7 ng/mL (at 3σ/slope) respectively. Meanwhile, the nanosensor shows good selectivity, sensitivity and can be successfully applied to detection of Sudan in chili powder samples.
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, PR China.
authors.forename: Aijin
authors.initials: A
authors.lastname: Fang
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, PR China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Long
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, PR China.
authors.forename: Qiongqiong
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, PR China.
authors.forename: Haitao
authors.initials: H
authors.lastname: Li
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, PR China. Electronic address: zhangyy@hunnu.edu.cn.
authors.forename: Youyu
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, PR China.
authors.forename: Shouzhuo
authors.initials: S
authors.lastname: Yao
mesh_terms: D001391:Azo Compounds / Q000032:analysis*; D015374:Biosensing Techniques / Q000379:methods*; D004396:Coloring Agents / Q000032:analysis*; D031541:Fluorescence Resonance Energy Transfer / Q000379:methods; D005503:Food Additives / Q000032:analysis; D053758:Nanoparticles / Q000737:chemistry*; D009284:Naphthols / Q000032:analysis*
chemical_list: D001391:Azo Compounds; D004396:Coloring Agents; D005503:Food Additives; D009284:Naphthols; C024336:1-phenylazo-2-naphthol; C009213:Scarlet Red
keywords: Fluorescence quenching; Inner filter effect; Sudan I–IV; Upconversion nanoparticles