title: Complete radiological response after sorafenib treatment for advanced hepato-cellular carcinoma.
abstract: BACKGROUND
  Sorafenib, an oral multikinase inhibitor, has recentlybeen shown to improve overall survival in patients with advanced hepatocellular carcinoma (HCC) but only a handful of reports of complete remission on sorafenib have been issued.
  
  
  METHODS
  We report an intriguing case of advanced HCC complicating HCV infection with cirrhosis, in which the patient achieved complete remission by prolonged administration of sorafenib.
  
  
  CONCLUSIONS
  Identifying factors that could be associated with good response to this therapy are needed.
authors.forename: Nour
authors.initials: N
authors.lastname: Elleuch
authors.forename: Rym
authors.initials: R
authors.lastname: Ennaifer
authors.forename: Hayfa
authors.initials: H
authors.lastname: Romdhane
authors.forename: Meryam
authors.initials: M
authors.lastname: Cheikh
authors.forename: Rania
authors.initials: R
authors.lastname: Hefaiedh
authors.forename: Wassila
authors.initials: W
authors.lastname: Bougassas
authors.forename: Houda
authors.initials: H
authors.lastname: Ben Nejma
authors.forename: Najet
authors.initials: N
authors.lastname: BelHadj
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications; D006801:Humans; D008103:Liver Cirrhosis / Q000821:virology; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D009367:Neoplasm Staging; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010671:Phenylurea Compounds / Q000627:therapeutic use*; D011859:Radiography; D012074:Remission Induction; D000077157:Sorafenib; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D010671:Phenylurea Compounds; D009536:Niacinamide; D000077157:Sorafenib