title: Primary gallbladder lymphoma presenting with perforated cholecystitis and hyperamylasaemia.
abstract: Primary gallbladder lymphoma is rare. Perforated cholecystitis due to primary gallbladder lymphoma and not related to chemotherapy has been unreported. We report the case of an 80-year-old woman presenting with an acute abdomen and clinical peritonitis. Her serum amylase was raised to 878 iu/l. Urgent computed tomography revealed generalised free fluid with a normal pancreas and was non-diagnostic as to the underlying pathology. An emergency laparotomy revealed bilious peritonitis with a necrotic patch on a distended gallbladder. A cholecystectomy was carried out and histology of the gallbladder revealed a marginal zone lymphoma.
authors.affiliation: University Hospital Southampton NHS Foundation Trust , UK.
authors.forename: K S V
authors.initials: KS
authors.lastname: Shah
authors.affiliation: University Hospital Southampton NHS Foundation Trust , UK.
authors.forename: V G
authors.initials: VG
authors.lastname: Shelat
authors.affiliation: University Hospital Southampton NHS Foundation Trust , UK.
authors.forename: S
authors.initials: S
authors.lastname: Jogai
authors.affiliation: University Hospital Southampton NHS Foundation Trust , UK.
authors.forename: V
authors.initials: V
authors.lastname: Trompetas
mesh_terms: D000006:Abdomen, Acute / Q000209:etiology; D000369:Aged, 80 and over; D002763:Cholecystectomy; D002764:Cholecystitis; D005260:Female; D005704:Gallbladder / Q000473:pathology / Q000601:surgery; D005706:Gallbladder Neoplasms; D006801:Humans; D034321:Hyperamylasemia; D008223:Lymphoma; D009336:Necrosis / Q000209:etiology; D010538:Peritonitis / Q000209:etiology; D014057:Tomography, X-Ray Computed
keywords: Gallbladder; Lymphoma; Perforation