title: [In Process Citation].
abstract: OBJECTIVE
  Different methods of open or minimally invasive thymectomies have been recommended for the treatment of myasthenia gravis (MG). We compared the results of standard transsternal thymectomy (TS) and two different types of minimally invasive thymectomies [video-assisted thoracoscopic extended thymectomy (VATET) and classic Video-Assisted Thoracoscopic Surgery (cVATS)] performed at the same department.
  
  
  METHODS
  During three different time periods 71 patients (60 female and 11 male; mean age 31 [range, 14-84] years) underwent thymectomy for MG. Twenty-three underwent standard transsternal thymectomy (January 1995 - September 2004), 22 VATET (September 2004 - August 2009), and 26 cVATS (September 2009 - December 2011) thymectomy for the right side. Operative data, MG- and surgery-related postoperative morbidity and early improvement of MG during the initial 1-year follow-up period were compared among the three methods.
  
  
  RESULTS
  There were no perioperative deaths during the study period. Operative time was 112, 211, and 116 minutes (p = 0.001) in the TS, VATET and cVATS, respectively, and the length of hospital stay was 8.9, 5.6, and 4.0 (p = 0.001) days. Postoperative MG-related neurological morbidity affected 21.7%, 18.2%, and 7.7% (p = 0.365) of the patients and the surgery-related morbidity rate was 4.3%, 13.7%, and 0% (p = 0.118) in the TS, VATET and cVATS groups, respectively. Symptom improvement rates were 91.3%, 94.7%, and 87.5% (p = 0.712), and complete remission rates were 13%, 10.5%, and 11.5% (p = 0.917) after TS, VATET and cVATS thymectomies, respectively.
  
  
  CONCLUSIONS
  In terms of operative time and hospital stay the best results were found after cVATS. The use of a less invasive surgical intervention resulted in less surgical-, and MG related neurological complications. The improvement of MG symptoms was excellent and results were similar after different types of thymectomies.
authors.affiliation: Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar 6720 Szeged, Szőkefalvi-Nagy Béla u. 6.
authors.forename: Aurél
authors.initials: A
authors.lastname: Ottlakán
authors.affiliation: Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar 6720 Szeged, Szőkefalvi-Nagy Béla u. 6.
authors.forename: Tibor
authors.initials: T
authors.lastname: Géczi
authors.affiliation: Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar 6720 Szeged, Szőkefalvi-Nagy Béla u. 6.
authors.forename: Balázs
authors.initials: B
authors.lastname: Pécsy
authors.affiliation: Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar 6720 Szeged, Szőkefalvi-Nagy Béla u. 6.
authors.forename: Bernadett
authors.initials: B
authors.lastname: Borda
authors.affiliation: Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar 6720 Szeged, Szőkefalvi-Nagy Béla u. 6.
authors.forename: Judit
authors.initials: J
authors.lastname: Lantos
authors.affiliation: Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar 6720 Szeged, Szőkefalvi-Nagy Béla u. 6.
authors.forename: György
authors.initials: G
authors.lastname: Lázár
authors.affiliation: Patológiai Intézet, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.
authors.forename: László
authors.initials: L
authors.lastname: Tiszlavicz
authors.affiliation: Neurológiai Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.
authors.forename: Péter
authors.initials: P
authors.lastname: Klivényi
authors.affiliation: Sebészeti Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar 6720 Szeged, Szőkefalvi-Nagy Béla u. 6.
authors.forename: József
authors.initials: J
authors.lastname: Furák
keywords: Video-Assisted Thoracic Surgery; myasthenia gravis; thymectomia; thymectomy; video-assisted thoracic surgery