title: Reversal agents in anaesthesia and critical care.
abstract: Despite the advent of short and ultra-short acting drugs, an in-depth knowledge of the reversal agents used is a necessity for any anaesthesiologist. Reversal agents are defined as any drug used to reverse the effects of anaesthetics, narcotics or potentially toxic agents. The controversy on the routine reversal of neuromuscular blockade still exists. The advent of newer reversal agents like sugammadex have made the use of steroidal neuromuscular blockers like rocuronium feasible in rapid sequence induction situations. We made a review of the older reversal agents and those still under investigation for drugs that are regularly used in our anaesthesia practice.
authors.affiliation: Department of Anaesthesiology and Critical Care, S.C.B Medical College, Cuttack, Odisha, India.
authors.forename: Nibedita
authors.initials: N
authors.lastname: Pani
authors.affiliation: Department of Emergency Medicine, Kempegouda Institute of Medical Sciences, Bengaluru, Karnataka, India.
authors.forename: Pradeep A
authors.initials: PA
authors.lastname: Dongare
authors.affiliation: Department of Anaesthesiology and Critical Care, S.C.B Medical College, Cuttack, Odisha, India.
authors.forename: Rajeeb Kumar
authors.initials: RK
authors.lastname: Mishra
keywords: Flumazenil; naloxone; platelet factor 4; sugammadex