title: Factors associated with extubation time in coronary artery bypass grafting patients.
abstract: Background and Objectives. Cardiovascular diseases are the leading cause of death worldwide, with coronary artery disease being the most common. With increasing numbers of patients, Coronary Artery Bypass Grafting (CABG) has become the most common operation in the world. Respiratory disorder is one of the most prevalent complications of CABG. Thus, weaning off the mechanical ventilation and extubation are of great clinical importance for these patients. Some post-operative problems also relate to the tracheal tube and mechanical ventilation. Therefore, an increase in this leads to an increase in the number of complications, length of hospital stay, and treatment costs. Since a large number of factors affect the post-operative period, the present study aims to identify the predictors of extubation time in CABG patients using casualty network analysis. Method. This longitudinal study was conducted on 800 over 18 year old patients who had undergone CABG surgery in three treatment centers affiliated to Shiraz University of Medical Sciences. The patients' information, including pre-operative, peri-operative, and post-operative variables, was retrospectively extracted from their medical records. Then, the data was comprehensively analyzed through path analysis using MPLUS-7.1 software. Results. The mean of extubation time was 10.27 + 4.39 h. Moreover, extubation time was significantly affected by packed cells during the Cardiopulmonary Bypass (CPB), packed cells after CPB, inotrope use on arrival at ICU, mean arterial pressure 1st ICU, packed cells 1st ICU, platelets 1st ICU, Blood Urea Nitrogen 1st ICU, and hematocrit 1st ICU. Conclusion. Considering all of the factors under investigation, some peri-operative and post-operative factors had significant effects. Therefore, considering the post-operative factors is important for designing a treatment plan and evaluating patients' prognosis.
authors.affiliation: Colorectal Research Center, Department of epidemiology, School of Health, Shiraz University of Medical Sciences , Shiraz , Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Rezaianzadeh
authors.affiliation: Department of Anesthesia, Shiraz Medical School, Shiraz University of Medical Sciences , Shiraz , Iran.
authors.forename: Behzad
authors.initials: B
authors.lastname: Maghsoudi
authors.affiliation: Department of Epidemiology, School of Health, Shiraz University of Medical Sciences , Shiraz Fars , Iran.
authors.forename: Hamidreza
authors.initials: H
authors.lastname: Tabatabaee
authors.affiliation: Department of Epidemiology, School of Health, Shiraz University of Medical Sciences , Shiraz Fars , Iran.
authors.forename: Sareh
authors.initials: S
authors.lastname: Keshavarzi
authors.affiliation: Department of Biostatistic, Shiraz Medical School, Shiraz University of Medical Sciences , Shiraz , Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Bagheri
authors.affiliation: Department of Physiology, School of Veterinary Medicine, Shiraz University , Shiraz , Iran.
authors.forename: Javad
authors.initials: J
authors.lastname: Sajedianfard
authors.affiliation: Department of Anesthesia, Shiraz Medical School, Shiraz University of Medical Sciences , Shiraz , Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Gerami
authors.affiliation: Department of Epidemiology, School of Health, Shiraz University of Medical Sciences , Shiraz Fars , Iran.
authors.forename: Javad
authors.initials: J
authors.lastname: Rasouli
keywords: Coronary Artery Bypass; Extubation; Risk factors