title: The role of negative pressure wound therapy in the management of hidradenitis suppurativa: a case report and literature review.
abstract: Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic, recurrent inflammatory disease affecting skin that bears apocrine glands. It is characterised by the presence of tender subcutaneous nodules that may rupture, resulting in deep dermal abscesses, fibrosis with dermal contractures and induration of the skin. The management of HS is a challenge for physicians as the pathogenesis is not clearly defined and prevents the use and development of directed therapies. Treatment options are oral agents (antibiotics, immunomodulators) and surgical excision. Historically, surgical management has been complicated by difficult closure and high recurrent rates. In the last 10 years, negative pressure wound therapy (NPWT) has proven to be a great adjunct for wound management as it provides the adequate conditions for wound healing, promotes granulation and helps to control infection. Here, we report a case of severe perineal HS treated with radical excision and NPWT as an adjunct. The patient only had a recurrence 3 years after primary treatment and was surgically treated for cosmetic reasons without any complications. Finally, we present a review of the relevant literature.
authors.affiliation: Department of General Surgery, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
authors.forename: Raphael
authors.initials: R
authors.lastname: Parrado
authors.affiliation: Department of General Surgery, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
authors.forename: Manuel
authors.initials: M
authors.lastname: Cadena
authors.affiliation: Department of General Surgery, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
authors.forename: Arturo
authors.initials: A
authors.lastname: Vergara
authors.affiliation: Department of Plastic Surgery, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
authors.forename: Diana
authors.initials: D
authors.lastname: Cadena
authors.affiliation: Department of Dermatology, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
authors.forename: Juan G
authors.initials: JG
authors.lastname: Chalela
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005260:Female; D017497:Hidradenitis Suppurativa / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy*; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D000072836:Surgical Wound / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D007155:Immunologic Factors
keywords: Acne inversa; Hidradenitis suppurativa; Negative pressure wound therapy; Split-thickness skin grafting