title: Controlled Cell Growth and Cell Migration in Periodic Mesoporous Organosilica/Alginate Nanocomposite Hydrogels.
abstract: Nanocomposite (NC) hydrogels with different periodic mesoporous organosilica (PMO) concentrations and a NC hydrogel bilayer with various PMO concentrations inside the layers of the hydrogel matrix are prepared. The effect of the PMO concentration on cell growth and migration of cells is reported. The cells migrate in the bilayer NC hydrogel towards higher PMO concentrations and from cell culture plates to NC hydrogel scaffolds.
authors.affiliation: Physikalisches Institut and CeNTech, Westfälische Wilhelms-Universität Münster, Heisenbergstraße 11, D-48149, Münster, Germany.
authors.forename: Nermin
authors.initials: N
authors.lastname: Seda Kehr
authors.affiliation: Physikalisches Institut and CeNTech, Westfälische Wilhelms-Universität Münster, Heisenbergstraße 11, D-48149, Münster, Germany.
authors.forename: Kristina
authors.initials: K
authors.lastname: Riehemann
mesh_terms: D016475:3T3 Cells; D000464:Alginates / Q000494:pharmacology*; D000818:Animals; D002452:Cell Count; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000187:drug effects*; D049109:Cell Proliferation / Q000187:drug effects; D020723:Glucuronic Acid / Q000494:pharmacology; D006603:Hexuronic Acids / Q000494:pharmacology; D020100:Hydrogels / Q000494:pharmacology*; D051379:Mice; D053761:Nanocomposites / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000494:pharmacology*; D016062:Porosity; D051381:Rats; D012822:Silicon Dioxide / Q000494:pharmacology*
chemical_list: D000464:Alginates; D006603:Hexuronic Acids; D020100:Hydrogels; D017646:Organosilicon Compounds; D012822:Silicon Dioxide; D020723:Glucuronic Acid
keywords: bilayer nanocomposite hydrogels; cell migration; nanoparticles; periodic mesoporous organosilica