title: ASSESSING BONE MINERAL DENSITY IN ITALIAN ADULT CYSTIC FIBROSIS PATIENTS: A CROSS SECTIONAL STUDY.
abstract: The purpose of this study was to assess bone mineral density in a cystic fibrosis (CF) outpatient clinic population and to investigate the relationship between BMD and forced expiratory volume in one second (FEV1), DEXA T-scores and 25-hidroxivitamin D (25-OHD) serum levels. We examined a consecutive series of 44 CF patients. Bone mass density was measured by dual-photon X-ray absorptiometry of lumbar spine and femur (total and neck) and lung function was performed in all patients. Medication data were obtained from medical records. A correlation analysis was performed to determine the relationship between BMD and forced expiratory volume in one second (FEV1), DEXA T-scores and 25-hidroxivitamin D (25-OHD) serum levels. In the results, age showed a significant inverse correlation indicating that as the age increases, bone density decreases and we concluded that most CF patients have low BMD and that there is a positive correlation with lung function and an inverse correlation with age.
authors.affiliation: Department of Neuroscience and Organs of Sense, Orthopedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Solarino
authors.affiliation: Department of Neuroscience and Organs of Sense, Orthopedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Vicenti
authors.affiliation: Department of Neuroscience and Organs of Sense, Orthopedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Spinarelli
authors.affiliation: Department of Orthopedics and Traumatology, Monsignor Raffaele Dimiccoli Hospital, Barletta, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Abate
authors.affiliation: Department of Neuroscience and Organs of Sense, Orthopedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Carrozzo
authors.affiliation: Department of Neurology, Neurorehabilitation and Spinal Unit, IRCCS Maugeri Foundation, Cassano Murge, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Cagnetta
authors.affiliation: Department of Neuroscience and Organs of Sense, Orthopedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Moretti