title: Methods in renal research: kidney transplantation in the rat.
abstract: Kidney transplantation in small animals has been crucial in the development of anti-rejection therapies. While there is no substitute for a skilled microsurgeon, there are many aspects of the transplant procedure that can be modified to optimize the reproducibility and utility of the technique. This article provides a detailed description, including video recording, of orthotopic kidney transplantation in the rat. The key variables in the technique are also discussed.
authors.affiliation: Department of Nephrology, Monash Health and Department of Medicine, Southern Clinical School, Monash University, Monash Medical Centre, Melbourne, Victoria, Australia.|Unicaen, Caen, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Tillou
authors.affiliation: Microsurgical Consultants, Melbourne, Victoria, Australia.
authors.forename: Brian O
authors.initials: BO
authors.lastname: Howden
authors.affiliation: Department of Nephrology, Monash Health and Department of Medicine, Southern Clinical School, Monash University, Monash Medical Centre, Melbourne, Victoria, Australia.
authors.forename: John
authors.initials: J
authors.lastname: Kanellis
authors.affiliation: Department of Nephrology, Monash Health and Department of Medicine, Southern Clinical School, Monash University, Monash Medical Centre, Melbourne, Victoria, Australia.
authors.forename: David J
authors.initials: DJ
authors.lastname: Nikolic-Paterson
authors.affiliation: Department of Nephrology, Monash Health and Department of Medicine, Southern Clinical School, Monash University, Monash Medical Centre, Melbourne, Victoria, Australia.
authors.forename: Frank Y
authors.initials: FY
authors.lastname: Ma
mesh_terms: D000208:Acute Disease; D000818:Animals; D035843:Biomedical Research / Q000379:methods*; D004195:Disease Models, Animal; D006084:Graft Rejection / Q000276:immunology* / Q000517:prevention & control; D006085:Graft Survival; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009398:Nephrology / Q000379:methods*; D011917:Rats, Inbred Lew; D013045:Species Specificity
keywords: arterial anastomosis; microsurgery; ureteric stent; venous anastomosis; video film