title: Devastating Delayed Leukoencephalopathy Associated with Bath Salt Inhalation.
abstract: "Bath salts" or synthetic cathinone toxicity remains a potentially deadly clinical condition. We report a delayed leukoencephalopathy with persistent minimally conscious state.
  
  
  
  Case report.
  
  
  
  A 36-year-old man presents with delayed encephalopathy, dysautonomia, fulminant hepatic failure, and renal failure from severe rhabdomyolysis after consuming bath salts. MRI showed diffusion restriction in the splenium of the corpus callosum and subcortical white matter.
  
  
  
  The combination of acute leukoencephalopathy, rhabdomyolysis and fulminant hepatic failure may point to bath salt inhalation and should be known to neurointensivists.
authors.affiliation: Division of Critical Care Neurology, Mayo Clinic Rochester, Rochester, MN, USA. ckramer82@gmail.com.
authors.forename: C L
authors.initials: CL
authors.lastname: Kramer
authors.affiliation: Department of Anesthesiology, Division of Critical Care, Mayo Clinic Rochester, Rochester, MN, USA.
authors.forename: D R
authors.initials: DR
authors.lastname: Wetzel
authors.affiliation: Division of Critical Care Neurology, Mayo Clinic Rochester, Rochester, MN, USA.
authors.forename: E F M
authors.initials: EF
authors.lastname: Wijdicks
mesh_terms: D000328:Adult; D000470:Alkaloids / Q000506:poisoning*; D052117:Benzodioxoles / Q000506:poisoning*; D003358:Cosmetics / Q000506:poisoning*; D006801:Humans; D056784:Leukoencephalopathies / Q000139:chemically induced*; D017093:Liver Failure / Q000139:chemically induced*; D008297:Male; D018458:Persistent Vegetative State / Q000139:chemically induced*; D011759:Pyrrolidines / Q000506:poisoning*; D051437:Renal Insufficiency / Q000139:chemically induced*; D012206:Rhabdomyolysis / Q000139:chemically induced; D000094982:Synthetic Cathinone
chemical_list: D000470:Alkaloids; D052117:Benzodioxoles; D003358:Cosmetics; D011759:Pyrrolidines; C023665:cathinone; D000094982:Synthetic Cathinone
keywords: 3,4-Methylenedioxypyrovalerone (MDPV); Acute liver failure; Bath salts; Bath salts toxicity; Cathinone toxicity; Dysautonomia; Fulminant hepatic failure; Leukoencephalopathy; Minimally conscious state; Neuroimaging; Rhabdomyolysis; Splenium of corpus callosum; Subcortical white matter