title: Signalling to the nucleus under the control of light and small molecules.
abstract: One major regulatory mechanism in cell signalling is the spatio-temporal control of the localization of signalling molecules. We synthetically designed an entire cell signalling pathway, which allows controlling the transport of signalling molecules from the plasma membrane to the nucleus, by using light and small molecules.
authors.affiliation: Faculty of Biology, University of Freiburg, Schänzlestraße 1, D-79104 Freiburg, Germany and Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, D-79104 Freiburg, Germany.
authors.forename: Samuel
authors.initials: S
authors.lastname: Juillot
authors.affiliation: Faculty of Biology, University of Freiburg, Schänzlestraße 1, D-79104 Freiburg, Germany and Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, D-79104 Freiburg, Germany.
authors.forename: Hannes M
authors.initials: HM
authors.lastname: Beyer
authors.affiliation: Faculty of Biology, University of Freiburg, Schänzlestraße 1, D-79104 Freiburg, Germany and BIOSS Centre for Biological Signalling Studies, University of Freiburg, Schänzlestraße 18, D-79104 Freiburg, Germany. winfried.roemer@bioss.uni-freiburg.de.
authors.forename: Josef
authors.initials: J
authors.lastname: Madl
authors.affiliation: Faculty of Biology, University of Freiburg, Schänzlestraße 1, D-79104 Freiburg, Germany and Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, D-79104 Freiburg, Germany.
authors.forename: Wilfried
authors.initials: W
authors.lastname: Weber
authors.affiliation: Faculty of Biology, University of Freiburg, Schänzlestraße 1, D-79104 Freiburg, Germany and BIOSS Centre for Biological Signalling Studies, University of Freiburg, Schänzlestraße 18, D-79104 Freiburg, Germany. winfried.roemer@bioss.uni-freiburg.de.
authors.forename: Matias D
authors.initials: MD
authors.lastname: Zurbriggen
authors.affiliation: Faculty of Biology, University of Freiburg, Schänzlestraße 1, D-79104 Freiburg, Germany and Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, D-79104 Freiburg, Germany.
authors.forename: Winfried
authors.initials: W
authors.lastname: Römer
mesh_terms: D021581:Active Transport, Cell Nucleus; D000595:Amino Acid Sequence; D029681:Arabidopsis Proteins / Q000502:physiology*; D051792:Basic Helix-Loop-Helix Proteins / Q000502:physiology; D002467:Cell Nucleus / Q000378:metabolism*; D010450:Endopeptidases / Q000502:physiology; D049452:Green Fluorescent Proteins / Q000096:biosynthesis / Q000235:genetics; D006367:HeLa Cells; D006801:Humans; D060847:Metabolic Engineering; D051939:Phytochrome B / Q000502:physiology*; D015398:Signal Transduction / Q000528:radiation effects*; D014162:Transfection
chemical_list: D029681:Arabidopsis Proteins; D051792:Basic Helix-Loop-Helix Proteins; D010450:Endopeptidases; D049452:Green Fluorescent Proteins; D051939:Phytochrome B; C497952:PHYB protein, Arabidopsis; C116162:PIF3 protein, Arabidopsis; C485184:enhanced green fluorescent protein; C099488:TEV protease