title: Acetaldehyde: A Small Organic Molecule with Big Impact on Organocatalytic Reactions.
abstract: Stereocontrolled formation of carbon-carbon and carbon-heteroatom bonds through asymmetric organocatalysis is a formidable challenge for modern synthetic chemistry. Among the most significant contributions to this field are the transformations involving the use of acetaldehyde or α-heteroatom-substituted acetaldehydes for constructing valuable synthons (e.g., amino acid derivatives and hydroxycarbonyl). In this Minireview, versatile (enantioselective) organocatalytic transformations are discussed.
authors.affiliation: Department of Energy Science, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 440-746, Korea.
authors.forename: Sun Min
authors.initials: SM
authors.lastname: Kim
authors.affiliation: Department of Energy Science, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 440-746, Korea.
authors.forename: Young Sug
authors.initials: YS
authors.lastname: Kim
authors.affiliation: Department of Energy Science, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 440-746, Korea.
authors.forename: Dong Wan
authors.initials: DW
authors.lastname: Kim
authors.affiliation: Faculty of Natural and Environmental Science, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK. R.Rios-Torres@southampton.ac.uk.
authors.forename: Ramon
authors.initials: R
authors.lastname: Rios
authors.affiliation: Department of Energy Science, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do, 440-746, Korea. jwyang@skku.edu.
authors.forename: Jung Woon
authors.initials: JW
authors.lastname: Yang
mesh_terms: D000079:Acetaldehyde / Q000737:chemistry*; D000596:Amino Acids / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D000079:Acetaldehyde
keywords: Mannich; Michael; acetaldehyde; aldols; carbenes; organocatalysis