title: Roles of Hsp70s in Stress Responses of Microorganisms, Plants, and Animals.
abstract: Hsp70s (heat shock protein 70s) are a class of molecular chaperones that are highly conserved and ubiquitous in organisms ranging from microorganisms to plants and humans. Most research on Hsp70s has focused on the mechanisms of their functions as molecular chaperones, but recently, studies on stress responses are coming to the forefront. Hsp70s play key roles in cellular development and protecting living organisms from environmental stresses such as heat, drought, salinity, acidity, and cold. Moreover, functions of human Hsp70s are related to diseases including neurological disorders, cancer, and virus infection. In this review, we provide an overview of the specific roles of Hsp70s in response to stress, particularly abiotic stress, in all living organisms.
authors.affiliation: Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China ; Yunnan Key Laboratory for Wild Plant Resources, Kunming, Yunnan 650201, China.
authors.forename: Anmin
authors.initials: A
authors.lastname: Yu
authors.affiliation: Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China ; Yunnan Key Laboratory for Wild Plant Resources, Kunming, Yunnan 650201, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.affiliation: Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China ; Yunnan Key Laboratory for Wild Plant Resources, Kunming, Yunnan 650201, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Tang
authors.affiliation: Key Laboratory of Tropical Plant Resource and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
authors.forename: Jiancai
authors.initials: J
authors.lastname: Wang
authors.affiliation: Yangjiang Forestry Administration, Dali, Yunnan 672401, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China ; Yunnan Key Laboratory for Wild Plant Resources, Kunming, Yunnan 650201, China.
authors.forename: Li
authors.initials: L
authors.lastname: Liu
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D018407:Bacterial Physiological Phenomena; D018840:HSP70 Heat-Shock Proteins / Q000737:chemistry / Q000145:classification / Q000502:physiology; D006801:Humans; D008969:Molecular Sequence Data; D018521:Plant Physiological Phenomena; D016415:Sequence Alignment; D013312:Stress, Physiological / Q000502:physiology*
chemical_list: D018840:HSP70 Heat-Shock Proteins