title: HIGH BODY MASS INDEX AMONG PATIENTS UNDERGOING HEMATOPOIETIC STEM CELL TRANSPLANTATION: RESULTS OF A CROSS-SECTIONAL EVALUATION OF NUTRITIONAL STATUS IN A PRIVATE HOSPITAL.
abstract: BACKGROUND
  nutritional status before hematopoietic stem cell transplantation (HSCT) affects prognosis: better nourished patients have shorter time to engraftment, while malnutrition is associated with increase of mortality rates, complications, medical costs, poor quality of life and hospitalization stay. Furthermore, underweight patients have increased risk of death in the early post- HSCT period, and non-relapse mortality is greater for those who are extremely underweight, overweight and obese. Obesity is associated with treatment-related toxicity, higher incidence of grade II-IV acute graft-versus- host disease (GVHD), infections and mortality. The objective of this study was to investigate the nutritional status of patients undergoing HSCT between 2007-2013 in a private hospital, by calculating the body mass index (BMI), to verify the prevalence of any nutritional imbalances, especially obesity.
  
  
  METHODS
  in this retrospective study, based on medical records, we analyzed data from all patients with malignant and nonmalignant diseases who underwent HSCT from January 2007 to February 2014 in the Hematology- Oncology and Bone Marrow Transplantation Center at a large, tertiary referral center in Brazil.
  
  
  RESULTS
  a total of 257 cases were treated in the period and analyzed, of which 79% were aged up to 65 years old. Among these, 56% were overweight or obese. We observed a higher prevalence of obesity in elderly patients (P < 0.001). The mean BMI of the total sample was 26.4 kg/m2. BMI was significantly different between genders, with higher prevalence of overweight among men (P < 0.001).
  
  
  CONCLUSIONS
  differently from other studies, our investigation has shown low rates of underweight and more overweight and obesity rates in men and elderly patients undergoing HSCT.
authors.affiliation: Oncology and Hematology Center of Hospital Israelita Albert Einstein, São Paulo.. dra.andrea.nutrologia@hotmail.com.
authors.forename: Andrea Z
authors.initials: AZ
authors.lastname: Pereira
authors.affiliation: Institute of Learning and Research of Hospital Israelita Albert Einstein, São Paulo.. dra.andrea.nutrologia@hotmail.com.
authors.forename: Elivane S
authors.initials: ES
authors.lastname: Victor
authors.affiliation: Oncology and Hematology Center of Hospital Israelita Albert Einstein, São Paulo.. dra.andrea.nutrologia@hotmail.com.
authors.forename: Paulo
authors.initials: P
authors.lastname: Vidal Campregher
authors.affiliation: Nutrition Department of Hospital Israelita Albert Einstein, São Paulo, Brazil.. dra.andrea.nutrologia@hotmail.com.
authors.forename: Silvia M F
authors.initials: SM
authors.lastname: Piovacari
authors.affiliation: Nutrition Department of Hospital Israelita Albert Einstein, São Paulo, Brazil.. dra.andrea.nutrologia@hotmail.com.
authors.forename: Juliana S
authors.initials: JS
authors.lastname: Bernardo Barban
authors.affiliation: Oncology and Hematology Center of Hospital Israelita Albert Einstein, São Paulo.. dra.andrea.nutrologia@hotmail.com.
authors.forename: Wilson L
authors.initials: WL
authors.lastname: Pedreira
authors.affiliation: Oncology and Hematology Center of Hospital Israelita Albert Einstein, São Paulo.. dra.andrea.nutrologia@hotmail.com.
authors.forename: Nelson
authors.initials: N
authors.lastname: Hamerschlak
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D006086:Graft vs Host Disease / Q000453:epidemiology; D018380:Hematopoietic Stem Cell Transplantation; D016304:Hospitals, Private; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D009765:Obesity / Q000150:complications; D050177:Overweight / Q000150:complications; D011379:Prognosis; D012189:Retrospective Studies; D013851:Thinness / Q000150:complications