title: Lipid Status and Predisposing Genes in Patients with Diabetes Mellitus Type 1 from Various Ethnic Groups.
abstract: The peculiarities of HLA class II profile and lipid metabolism were examined in Buryat and Russian ethnic groups of patients with diabetes mellitus type 1. The incidence of type 1 haplotypes in HLA class II gene family was lower in Buryats than that in Russians. In comparison with Russians, the course of diabetes mellitus type 1 in Buryat patients was characterized with a lower content of total lipids, triacylglycerols, total cholesterol, and LDL, which probably explains a more favorable course of the disease in Buryat population.
authors.affiliation: Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
authors.forename: L I
authors.initials: LI
authors.lastname: Kolesnikova
authors.affiliation: Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
authors.forename: S I
authors.initials: SI
authors.lastname: Kolesnikov
authors.affiliation: Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia. mops_my@front.ru.
authors.forename: M A
authors.initials: MA
authors.lastname: Darenskaya
authors.affiliation: Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
authors.forename: L A
authors.initials: LA
authors.lastname: Grebenkina
authors.affiliation: Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Semenova
authors.affiliation: Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Osipova
authors.affiliation: Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
authors.forename: S V
authors.initials: SV
authors.lastname: Gnusina
authors.affiliation: Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
authors.forename: T A
authors.initials: TA
authors.lastname: Bardymova
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics* / Q000378:metabolism*; D005006:Ethnicity / Q000235:genetics; D005260:Female; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D006801:Humans; D008297:Male; D012426:Russia; D044465:White People / Q000235:genetics
chemical_list: D000949:Histocompatibility Antigens Class II
keywords: diabetes mellitus type 1; ethnos; lipid metabolism; predisposing genes