title: Silver-catalyzed oxidative decarboxylation of difluoroacetates: efficient access to C-CF2 bond formation.
abstract: A mild, versatile and efficient method for the silver(I)-catalyzed oxidative decarboxylative gem-difluoromethylenation has been developed. The radical cascade reaction comprises the addition of an oxidatively generated difluoromethylene radical to the isonitrile functionality and subsequent homolytic aromatic substitution. It provides a novel and efficient access to the C-CF2 bond formation.
authors.affiliation: Department of Chemistry, School of Material Science and Engineering, Innovative Drug Research Center, Shanghai University, China. wanwen@staff.shu.edu.cn jhao@shu.edu.cn.
authors.forename: Wen
authors.initials: W
authors.lastname: Wan
authors.forename: Guobin
authors.initials: G
authors.lastname: Ma
authors.forename: Jialiang
authors.initials: J
authors.lastname: Li
authors.forename: Yunrong
authors.initials: Y
authors.lastname: Chen
authors.forename: Qingyang
authors.initials: Q
authors.lastname: Hu
authors.forename: Minjie
authors.initials: M
authors.lastname: Li
authors.forename: Haizhen
authors.initials: H
authors.lastname: Jiang
authors.forename: Hongmei
authors.initials: H
authors.lastname: Deng
authors.forename: Jian
authors.initials: J
authors.lastname: Hao