title: Secondary syphilis presenting with aortitis and coronary ostial occlusion.
abstract: Aortitis is an established manifestation of tertiary syphilis. We report a rare case of aortitis with ostial occlusion and left ventricular failure in secondary syphilis. Her management required a true multidisciplinary approach from multiple specialities due to complications of concomitant psychosis and a history of anaphylaxis to penicillin. This case illustrates the complexities of diagnosing and managing a rare presentation of this increasingly prevalent infection.
authors.affiliation: Department of Cardiology, University Hospital of South Manchester, UK.
authors.forename: John A
authors.initials: JA
authors.lastname: Chadwick
authors.affiliation: Department of Cardiology, University Hospital of South Manchester, UK.
authors.forename: Anita
authors.initials: A
authors.lastname: MacNab
authors.affiliation: Department of Cardiology, University Hospital of South Manchester, UK.
authors.forename: Jaydeep
authors.initials: J
authors.lastname: Sarma
authors.affiliation: Department of Cardiology, University Hospital of South Manchester, UK.
authors.forename: Simon
authors.initials: S
authors.lastname: Ray
authors.affiliation: Department of Cardiothoracic Surgery, University Hospital of South Manchester, UK.
authors.forename: Isaac
authors.initials: I
authors.lastname: Kadir
authors.affiliation: Department of Infectious Diseases, University Hospital of South Manchester, UK The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
authors.forename: Eavan G
authors.initials: EG
authors.lastname: Muldoon
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000382:microbiology*; D023921:Coronary Stenosis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology / Q000601:surgery; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use*; D013587:Syphilis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D013589:Syphilis, Cardiovascular / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D008775:Methylprednisolone
keywords: CLINICAL CARE (GENERAL); PENICILLIN; SYPHILIS