title: [Determination of total Bromine in urine by inductively coupled plasma mass spectrometry (ICP-MS)].
abstract: OBJECTIVE
  To establish a method to determine total bromine in urine.
  
  
  METHODS
  Diluted urine samples were directly introduced into ICP-MS then quantized by standard curve.
  
  
  RESULTS
  Total bromine in urine was linear within 1.0~50 mg/L with r > 0.999, When spiked at a concentration of 0.020 mg/L, 0.050 mg/L, 0.150 mg/L, the recovery was 95%~98%, intra-assay precision was 1.4% 3.2%, inter-assay precision was 3.4% to 5.0%. Urine could store in -20 °C refrigerator 3 months without any bromine loss.
  
  
  CONCLUSIONS
  Using ICP-MS to determine the urinary total bromine, the method is fast, accurate, wide linear range of features, could meet with the requirement of Part 5 of occupational health standards guide: Method determination of chemical substances in biological materials (GBZ/T 210.5-2008), a strong competitive advantage in a wide range of survey, suitable for promotion.
authors.affiliation: Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Changmei
authors.initials: C
authors.lastname: Zhou
authors.forename: Hangju
authors.initials: H
authors.lastname: Zhu
authors.forename: Deye
authors.initials: D
authors.lastname: Liu
authors.forename: Rongming
authors.initials: R
authors.lastname: Miao
authors.forename: Lihong
authors.initials: L
authors.lastname: Ying
authors.affiliation: E-mail: zhubl@jscdc.cn.
authors.forename: Baoli
authors.initials: B
authors.lastname: Zhu
mesh_terms: D001966:Bromine / Q000652:urine*; D006801:Humans; D013058:Mass Spectrometry
chemical_list: D001966:Bromine