title: Visible-Light-Induced Hydrodifluoromethylation of Alkenes with a Bromodifluoromethylphosphonium Bromide.
abstract: Bromodifluoromethylphosphonium bromide was solely used as the precursor of difluorocarbene. Herein, an unprecedented visible-light-induced hydrodifluoromethylation of alkenes with bromodifluoromethylphosphonium bromide using H2O and THF as hydrogen sources for the synthesis of difluoromethylated alkanes is described. This difluoromethylation is characterized by mild reaction conditions, ready availability of reagents, and excellent functional-group tolerance.
authors.affiliation: KeyLaboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Lingling Lu, Shanghai, 200032, China.
authors.forename: Qing-Yu
authors.initials: QY
authors.lastname: Lin
authors.affiliation: KeyLaboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Lingling Lu, Shanghai, 200032, China.
authors.forename: Xiu-Hua
authors.initials: XH
authors.lastname: Xu
authors.affiliation: College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, 2999 North Renmin Lu, Shanghai, 201620, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Zhang
authors.affiliation: KeyLaboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, 345 Lingling Lu, Shanghai, 200032, China. flq@mail.sioc.ac.cn.|College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, 2999 North Renmin Lu, Shanghai, 201620, China. flq@mail.sioc.ac.cn.
authors.forename: Feng-Ling
authors.initials: FL
authors.lastname: Qing
keywords: alkenes; fluorine; photoredox catalysis; radicals; synthetic methods