title: [Diabetes increases the risk of fractures].
abstract: Diabetes is associated with an increased risk of fracture, however, neither bone mineral density, falls, diabetes complications nor other risk factors can explain why. Among patients with diabetes, hyperglycaemia may have detrimental effects on bone, but also use of anti-diabetic treatment may have an impact on fracture risk. In this article we assess the relationship between diabetes, bone and fracture and the effects of hyperglycaemia and anti-diabetic treatment on bone. Furthermore, fracture preventive measures in patients with diabetes are evaluated.
authors.affiliation: jakob.Linde@auh.rm.dk.
authors.forename: Jakob
authors.initials: J
authors.lastname: Starup-Linde
authors.forename: Azra
authors.initials: A
authors.lastname: Karahasanovic
authors.forename: Peter
authors.initials: P
authors.lastname: Vestergaard
authors.forename: Pia
authors.initials: P
authors.lastname: Eiken
mesh_terms: D015519:Bone Density / Q000502:physiology; D016723:Bone Remodeling / Q000502:physiology; D048909:Diabetes Complications / Q000378:metabolism / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology; D050723:Fractures, Bone / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D006943:Hyperglycemia / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D007004:Hypoglycemic Agents / Q000009:adverse effects / Q000627:therapeutic use; D012307:Risk Factors; D045162:Thiazolidinediones / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D007004:Hypoglycemic Agents; D045162:Thiazolidinediones