title: Human health risk assessment of heavy metals in cosmetics in Nigeria.
abstract: Forty two different cosmetics were purchased from supermarkets and cosmetic shops within Unitsha Main Market and Eke-Awka markets in Anambra, Nigeria. Of the cosmetics, 16% were locally manufactured in Nigeria while 83.33% were imported into Nigeria. The cosmetics were ashed before digestion and filtration. The filtrates were assayed for lead, cadmium, manganese, nickel, chromium, mercury, and arsenic with atomic absorption spectrophotometry at 205 Å. The health risk assessment methods developed by the United States Environmental Protection Agency were employed to explore the potential human health risk of heavy metals in cosmetics. About 61.91% of the cosmetic samples contained lead with concentration in the range of 0.10-42.12 mg/kg. Cadmium levels of the cosmetics ranged from 0.01 to 1.32 mg/kg, manganese from 0.02 to 67.65 mg/kg, nickel from 0.05 to 17.34 mg/kg, chromium from 0.11 to 9.81 mg/kg, mercury from 0.003 to 0.07 mg/kg, and arsenic from 0.002 to 0.005 mg/kg. Although the target hazard quotients and the hazard indices suggest a measure of safety, cosmetics may add to the body burden of potential toxic metals after chronic exposure.
authors.forename: John K
authors.initials: JK
authors.lastname: Nduka
authors.lastname: Odiba
authors.forename: Orish E
authors.initials: OE
authors.lastname: Orisakwe
authors.forename: Linda D
authors.initials: LD
authors.lastname: Ukaebgu
authors.forename: Chinwetuto
authors.initials: C
authors.lastname: Sokaibe
authors.forename: Nnaemeka A
authors.initials: NA
authors.lastname: Udowelle
mesh_terms: D003358:Cosmetics / Q000737:chemistry* / Q000633:toxicity*; D006801:Humans; D019216:Metals, Heavy / Q000737:chemistry* / Q000633:toxicity*; D009549:Nigeria; D018570:Risk Assessment
chemical_list: D003358:Cosmetics; D019216:Metals, Heavy