title: Changes in choroidal thickness after prophylactic iridectomy in primary angle closure suspect eyes using enhanced depth imaging optical coherence tomography.
abstract: OBJECTIVE
  The aim of the present study was to evaluate the effect of surgical peripheral iridectomy (SPI) on choroidal thickness in primary angle-closure suspect (PACS) eyes.
  
  
  METHODS
  This was a prospective observational case series of 30 subjects with PACS. Ocular biometry was performed before SPI (baseline) and then 1 week later. Choroid was imaged by enhanced depth imaging optical coherence tomography (EDI-OCT). The choroidal thickness of the subfoveal area at 1 and 3 mm diameter around the fovea was determined. Central anterior chamber depth (ACD), lens thickness (LT), vitreous chamber depth (VCD), and axial length (AL) were measured by A-scan ultrasound. Parameters were compared before SPI (baseline) and 1 week later.
  
  
  RESULTS
  Thirty eyes of 30 patients with mean age of 61.53 ± 7.98 years were studied. There was no significant difference in the choroidal thickness at all macular locations before and after SPI (all P > 0.05). Mean subfoveal choroidal thickness was 279.61 μm ± 65.50 μm before and 274.54 μm ± 63.36 μm after SPI (P = 0.308). There was also no significant change in central ACD, LT, VCD, and LT after SPI (all P > 0.05).
  
  
  CONCLUSIONS
  SPI does not appear to alter choroidal thickness in PACS eyes, as assessed using EDI-OCT. Long-term follow-up of PACS eyes treated with SPI may provide further insight into the effects of this treatment modality on the choroid.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Minwen
authors.initials: M
authors.lastname: Zhou
authors.forename: Wenbin
authors.initials: W
authors.lastname: Huang
authors.forename: Xinbo
authors.initials: X
authors.lastname: Gao
authors.affiliation: Department of Glaucoma, Clinical Research Center, Institution of Drug Clinical Trials, Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, 54S.Xianlie Road, Guangzhou 510060, People's Republic of China.
authors.forename: Xiulan
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000000981:diagnostic imaging; D058452:Axial Length, Eye / Q000000981:diagnostic imaging; D001699:Biometry; D002829:Choroid / Q000473:pathology*; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000503:physiopathology / Q000601:surgery*; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure; D032801:Iridectomy; D007908:Lens, Crystalline / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011446:Prospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D014822:Vitreous Body / Q000000981:diagnostic imaging