title: Octreotide in malignant chylothorax: a case report.
abstract: The treatment of malignancy-associated chylous pleural effusion and ascites, especially in the palliative setting, represents a major therapeutic challenge. Our patient, a case of metastatic lung cancer, was suffering from high-output, non-resolving, malignancy-related chylothorax. We found that subcutaneous octreotide in combination with fasting and total parenteral nutrition, followed later by institution of low-fat diet, resulted in its resolution. We suggest that it is a reasonable approach associated with minimal morbidity in what is otherwise a challenging clinical condition.
authors.affiliation: Department of Medical Oncology, Asian Cancer Center, Faridabad, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Gupta
authors.affiliation: Department of Medical Oncology, Artemis Cancer Hospital, Gurgaon, India.
authors.forename: Taranjit
authors.initials: T
authors.lastname: Singh
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D002916:Chylothorax / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D018931:Antineoplastic Agents, Hormonal; D015282:Octreotide
keywords: Clinical decisions; Drug administration; Hospital care; Supportive care