title: Performance of the new American College of Rheumatology classification criteria in Turkish systemic sclerosis patients: a multicenter study.
abstract: In our study, we compared the sensitivity and specificity of the new ACR/EULAR 2013 criteria to the ACR 1980 criteria in our systemic sclerosis (SSc) population. Three rheumatology centers from Turkey participated into this study. The medical records of SSc patients diagnosed between 2008 and 2014 were retrospectively reviewed, and their features at disease onset were recorded. Patients admitted to each center within the same time period for conditions other than SSc, in whom ANA was positive and was deemed necessary within the diagnostic workup, were included as controls. One hundred and ninety-seven SSc patients (174 females, 23 males) and 103 controls (96 females, 7 males) were included. Limited cutaneous SSc was present in 68 % of patients, and 30.5 % had diffuse SSc. The sensitivity of ACR/EULAR 2013 and ACR 1980 criteria were, respectively, 94.4 and 85.3 % (p = 0.003). The specificity of ACR/EULAR 2013 and ACR 1980 criteria were, respectively, 98.1 and 100 %. According to the new criteria, 13 patients were misclassified; however, according to the ACR 1980 criteria, 29 patients were misclassified (p = 0.005). The sensitivity of ACR/EULAR 2013 criteria was significantly better than that of the ACR 1980 criteria in limited cutaneous SSc group (94.8 vs. 82.8 %). In patients whose disease duration was <3 years, the new criteria had better sensitivity than the previous criteria (92.7 vs. 78.1 %, p = 0.006). The new ACR/EULAR 2013 criteria for SSc had better sensitivity in Turkish SSc patients, and less patients were misclassified.
authors.affiliation: Department of Rheumatology, Trakya University Medical Faculty, Eski Yildiz Cad. Park Apt. No:22, Daire:18, 34349, Besiktas-Istanbul, Edirne, Turkey. omernpamuk@yahoo.com.
authors.forename: Omer Nuri
authors.initials: ON
authors.lastname: Pamuk
authors.affiliation: Department of Rheumatology, Trakya University Medical Faculty, Eski Yildiz Cad. Park Apt. No:22, Daire:18, 34349, Besiktas-Istanbul, Edirne, Turkey.
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Balcı
authors.affiliation: Department of Rheumatology, Gaziantep University Medical Faculty, Gaziantep, Turkey.
authors.forename: Ahmet Mesut
authors.initials: AM
authors.lastname: Onat
authors.affiliation: Department of Rheumatology, Trakya University Medical Faculty, Eski Yildiz Cad. Park Apt. No:22, Daire:18, 34349, Besiktas-Istanbul, Edirne, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Zengin
authors.affiliation: Department of Rheumatology, Fatih Sultan Mehmet Research and Training Hospital, Istanbul, Turkey.
authors.forename: Necati
authors.initials: N
authors.lastname: Cakır
authors.affiliation: Department of Rheumatology, Gaziantep University Medical Faculty, Gaziantep, Turkey.
authors.forename: Bunyamin
authors.initials: B
authors.lastname: Kısacık
mesh_terms: D000328:Adult; D000465:Algorithms; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012219:Rheumatology / Q000592:standards; D012595:Scleroderma, Systemic / Q000145:classification / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D014421:Turkey
keywords: ACR criteria; Performance; Sensitivity; Specificity; Systemic sclerosis