title: Impact of surgical margin clearance for resection of secondary hepatic malignancies.
abstract: Over the past several decades, there has been increasing discussion regarding the optimal management of secondary liver malignancies. Traditionally, resection has only been recommended if it could be accomplished with negative microscopic margins of at least 10 mm. However, many investigators have pushed this limit to offer resection to patients with narrower margins. We review the data regarding the impact of margin clearance on outcomes for patients undergoing hepatic metastasectomy.
authors.affiliation: Department of Surgery, Division of Surgical Oncology, University of Louisville, Louisville, Kentucky.
authors.forename: Neal
authors.initials: N
authors.lastname: Bhutiani
authors.affiliation: Department of Surgery, Division of Surgical Oncology, University of Louisville, Louisville, Kentucky.
authors.forename: Prejesh
authors.initials: P
authors.lastname: Philips
authors.affiliation: Department of Surgery, Division of Surgical Oncology, University of Louisville, Louisville, Kentucky.
authors.forename: Robert C G
authors.initials: RC
authors.lastname: Martin
authors.affiliation: Department of Surgery, Division of Surgical Oncology, University of Louisville, Louisville, Kentucky.
authors.forename: Charles R
authors.initials: CR
authors.lastname: Scoggins
mesh_terms: D015179:Colorectal Neoplasms / Q000473:pathology; D005629:Frozen Sections; D006498:Hepatectomy / Q000592:standards*; D006801:Humans; D007432:Intraoperative Period; D008113:Liver Neoplasms / Q000401:mortality / Q000517:prevention & control / Q000556:secondary* / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D018365:Neoplasm, Residual / Q000517:prevention & control; D018358:Neuroendocrine Tumors / Q000556:secondary / Q000601:surgery; D015996:Survival Rate; D016896:Treatment Outcome
keywords: colorectal liver metastases; frozen section analysis; non-colorectal liver metastases; resection margin; secondary liver malignancy