title: Molecularly imprinted polymers for separating and sensing of macromolecular compounds and microorganisms.
abstract: The present review article focuses on gathering, summarizing, and critically evaluating the results of the last decade on separating and sensing macromolecular compounds and microorganisms with the use of molecularly imprinted polymer (MIP) synthetic receptors. Macromolecules play an important role in biology and are termed that way to contrast them from micromolecules. The former are large and complex molecules with relatively high molecular weights. The article mainly considers chemical sensing of deoxyribonucleic acids (DNAs), proteins and protein fragments as well as sugars and oligosaccharides. Moreover, it briefly discusses fabrication of chemosensors for determination of bacteria and viruses that can ultimately be considered as extremely large macromolecules.
authors.affiliation: Department of Physical Chemistry of Supramolecular Complexes, Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
authors.forename: Zofia
authors.initials: Z
authors.lastname: Iskierko
authors.affiliation: Department of Physical Chemistry of Supramolecular Complexes, Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland. Electronic address: psharma@ichf.edu.pl.
authors.forename: Piyush Sindhu
authors.initials: PS
authors.lastname: Sharma
authors.affiliation: Department of Physical Chemistry of Supramolecular Complexes, Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Bartold
authors.affiliation: Department of Physical Chemistry of Supramolecular Complexes, Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland. Electronic address: apietrzyk@ichf.edu.pl.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Pietrzyk-Le
authors.affiliation: Department of Physical Chemistry of Supramolecular Complexes, Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland. Electronic address: knoworyta@ichf.edu.pl.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Noworyta
authors.affiliation: Department of Physical Chemistry of Supramolecular Complexes, Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland; Faculty of Mathematics and Natural Sciences, School of Science, Cardinal Stefan Wyszynski University in Warsaw, Wóycickiego 1/3, 01-815 Warsaw, Poland. Electronic address: wkutner@ichf.edu.pl.
authors.forename: Wlodzimierz
authors.initials: W
authors.lastname: Kutner
mesh_terms: D001419:Bacteria / Q000302:isolation & purification; D002241:Carbohydrates / Q000032:analysis; D004247:DNA / Q000032:analysis; D046911:Macromolecular Substances / Q000032:analysis* / Q000302:isolation & purification*; D054802:Molecular Imprinting; D009841:Oligonucleotides / Q000032:analysis; D011108:Polymers / Q000737:chemistry*; D011506:Proteins / Q000032:analysis; D014780:Viruses / Q000302:isolation & purification
chemical_list: D002241:Carbohydrates; D046911:Macromolecular Substances; D009841:Oligonucleotides; D011108:Polymers; D011506:Proteins; D004247:DNA
keywords: Bacteria; Chemosensor; Molecularly imprinted polymer; Oligonucleotide; Protein; Virus