title: Doppler ultrasonography helps discriminate between cirrhotic and non-cirrhotic patients with viral B and C hepatitis.
abstract: OBJECTIVE
  The aim of this study was to define the cutoff values between compensated cirrhosis and non-cirrhotic patients with viral hepatitis B and C, using the criteria of the Doppler parameters of liver vascularity.
  
  
  METHODS
  Seventy non-cirrhotic patients with viral hepatitis B and C and 30 cirrhotic patients were included in this prospective study. The diagnostic decisiveness properties of the Doppler values in the pre-determination of liver cirrhosis were evaluated using receiver operating characteristics curve analysis.
  
  
  RESULTS
  Taking the cutoff value for hepatic vein waveform index as 0.605, a sensitivity of 80% and a specificity of 77.1% were obtained. The sensitivity was 80%, and the specificity was 68.6% for a mean max portal velocity cutoff value of 18.25cm/s. When the hepatic artery resistivity index cutoff value was taken as 0.705 for the diagnosis of cirrhosis, the sensitivity was 82.5% and the specificity 72.1%. For a hepatic artery pulsatility index cutoff value of 1.295, a sensitivity of 82.5% and a specificity of 72.1% were found.
  
  
  CONCLUSIONS
  It is not possible to diagnose cirrhosis with only hemodynamic changes. However, the cutoff values may be helpful in the selection of patients to undergo the procedure of liver biopsy.
authors.affiliation: Department of Radiology, Numune Teaching and Research Hospital, Adana, Turkey. Electronic address: gsoker@hotmail.com.
authors.forename: G
authors.initials: G
authors.lastname: Soker
authors.affiliation: Department of Family Medicine, Adiyaman University School of Medicine, Adiyaman, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Bahadir Ozturk
authors.affiliation: Department of Radiology, Numune Teaching and Research Hospital, Adana, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Gulek
authors.affiliation: Department of Infectious Disease and Microbiology, Numune Teaching and Research Hospital, Adana, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Kuscu
authors.affiliation: Department of Gastroenterology, Mustafa Kemal University School of Medicine, Adana, Turkey.
authors.forename: U
authors.initials: U
authors.lastname: Bilge Doğan
authors.affiliation: Department of Radiology, Numune Teaching and Research Hospital, Adana, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Yilmaz
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D019694:Hepatitis B, Chronic / Q000150:complications*; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D018608:Ultrasonography, Doppler
keywords: Cirrhosis; Doppler ultrasonography; Hepatic artery; Hepatic veins; Portal flow