title: Cardiac neuroendocrine tumour metastases: case reports and review of the literature.
abstract: BACKGROUND
  Most neuroendocrine tumours (NETs) metastasize to the liver, lymph nodes and, although less frequently, to the bone. The heart is a rare localization for NET metastases.
  
  
  METHODS
  With the introduction of the Ga-DOTATATE PET/computed tomography (CT) in our hospital as a new diagnostic method for imaging neuroendocrine tumours, more rare metastatic localizations are being found. We present six cases of patients with cardiac NET metastases detected by Ga-DOTATATE PET/CT. Also, a review of literature is presented on case reports of cardiac NET metastases in patients detected by somatostatin receptor imaging, including In-Pentetreotide single photon emission computed tomography/CT, Ga-DOTATATE PET/CT, Ga-DOTANOC PET/CT or Ga-DOTATOC PET/CT.
  
  
  CONCLUSIONS
  Most patients with cardiac NET metastases have extensive metastatic disease. The cardiac metastases are often asymptomatic.
authors.affiliation: Departments of aNuclear Medicine bMedical Oncology, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
authors.forename: Lisanne R
authors.initials: LR
authors.lastname: Bonsen
authors.forename: Else A
authors.initials: EA
authors.lastname: Aalbersberg
authors.forename: Margot
authors.initials: M
authors.lastname: Tesselaar
authors.forename: Marcel P M
authors.initials: MP
authors.lastname: Stokkel
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D009942:Organometallic Compounds; D000072078:Positron Emission Tomography Computed Tomography
chemical_list: D009942:Organometallic Compounds; C513399:gallium Ga 68 dotatate