title: HEMATOLOGICAL AND IMMUNOBIOCHEMICAL STUDY OF GREEN TEA AND GINGER EXTRACTS IN EXPERIMENTALLY INDUCED DIABETIC RABBITS.
abstract: The present study was designed to investigate the effects of the extract of green tea and/or ginger on some hematological and immunobiochemical profiles in alloxan-induced diabetic rabbits. The results revealed that treatment of diabetic animals with extract of green tea and/or ginger elevated the decreased HDL-c and LDL-c but significantly decreased triglycerides, the elevated glucose and GOT concentrations. The result also displayed a non-significant increase in the levels of CRP and fibrinogen. The experiment also revealed that the elevated MDA and GSH level fell down to the normal control group. The result also showed that after green tea and/or ginger extract treatment, the lowered RBC, WBC counts, PCV, percentage of neutrophils were increased and the elevated MCV, MCH, and MCHC of diabetic rabbits were decreased to normal levels. Thus, the overall results may indicate that green tea and/or ginger extracts have a significant hypoglycemic effect in diabetic rabbits. In addition, the extracts may be capable of improving hyperlipidemia, the impaired kidney function and hemogram in alloxan-induced diabetic rabbits.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Elkirdasy
authors.forename: Saad
authors.initials: S
authors.lastname: Shousha
authors.forename: Abdulmohsen H
authors.initials: AH
authors.lastname: Alrohaimi
authors.forename: M Faiz
authors.initials: MF
authors.lastname: Arshad
mesh_terms: D000496:Alloxan; D000818:Animals; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D020939:Zingiber officinale; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D011817:Rabbits; D013662:Tea
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D013662:Tea; D000496:Alloxan