title: Surgery for Aortic Dilatation in Patients With Bicuspid Aortic Valves: A Statement of Clarification From the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.
abstract: Two guidelines from the American College of Cardiology (ACC), the American Heart Association (AHA), and collaborating societies address the risk of aortic dissection in patients with bicuspid aortic valves and severe aortic enlargement: the "2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease" (J Am Coll Cardiol 2010;55:e27-130) and the "2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease" (J Am Coll Cardiol 2014;63:e57-185). However, the 2 guidelines differ with regard to the recommended threshold of aortic root or ascending aortic dilatation that would justify surgical intervention in patients with bicuspid aortic valves. The ACC and AHA therefore convened a subcommittee representing members of the 2 guideline writing committees to review the evidence, reach consensus, and draft a statement of clarification for both guidelines. This statement of clarification uses the ACC/AHA revised structure for delineating the Class of Recommendation and Level of Evidence to provide recommendations that replace those contained in Section 9.2.2.1 of the thoracic aortic disease guideline and Section 5.1.3 of the valvular heart disease guideline.
authors.forename: Loren F
authors.initials: LF
authors.lastname: Hiratzka
authors.forename: Mark A
authors.initials: MA
authors.lastname: Creager
authors.forename: Eric M
authors.initials: EM
authors.lastname: Isselbacher
authors.forename: Lars G
authors.initials: LG
authors.lastname: Svensson
authors.forename: Rick A
authors.initials: RA
authors.lastname: Nishimura
authors.forename: Robert O
authors.initials: RO
authors.lastname: Bonow
authors.forename: Robert A
authors.initials: RA
authors.lastname: Guyton
authors.forename: Thoralf M
authors.initials: TM
authors.lastname: Sundt
mesh_terms: D000572:American Heart Association; D017545:Aortic Aneurysm, Thoracic / Q000209:etiology / Q000601:surgery*; D001021:Aortic Valve / Q000002:abnormalities*; D000082882:Bicuspid Aortic Valve Disease; D002309:Cardiology / Q000592:standards*; D019468:Disease Management; D006349:Heart Valve Diseases / Q000150:complications*; D006801:Humans; D014481:United States; D014656:Vascular Surgical Procedures / Q000592:standards*
keywords: ACC/AHA Clinical Practice Guidelines; anticoagulation therapy; heart valves; thoracic aortic aneurysm; thoracic aortic disease; thoracic aortic dissection; valvular heart disease