title: SEOM guidelines for the management of Malignant Melanoma 2015.
abstract: All melanoma patients must be confirmed histologically and resected according to Breslow. Sentinel node biopsy must be done when tumor is over 1 mm or if less with high-risk factors. Adjuvant therapy with interferon must be offered for patients with high-risk melanoma and in selected cases radiotherapy can be added. Metastatic melanoma treatment is guided by mutational BRAF status. BRAF wild type patients must receive anti-PD1 therapy and BRAF mutated patients BRAF/MEK inhibitors or anti-PD1 therapy. Up to 10 years follow up is recommended for melanoma patients with dermatologic examinations and physical exams.
authors.affiliation: Servicio de Oncología Médica, Consorcio Hospital General Universitario de Valencia, Avda. Tres Cruces 2, 46014, Valencia, Spain. berrocal.alf@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Berrocal
authors.affiliation: Hospital Clinic I Provincial de Barcelona, Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Arance
authors.affiliation: Hospital Universitario la Paz, Madrid, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Espinosa
authors.affiliation: Hospital Universitario Marqués de Valdecilla, Santander, Spain.
authors.forename: A G
authors.initials: AG
authors.lastname: Castaño
authors.affiliation: Hospital Universitario Quirón Dexeus, Barcelona, Spain.
authors.forename: M G
authors.initials: MG
authors.lastname: Cao
authors.affiliation: Hospital Universitario Clínico San Carlos, Madrid, Spain.
authors.forename: J L G
authors.initials: JL
authors.lastname: Larriba
authors.affiliation: Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: J A L
authors.initials: JA
authors.lastname: Martín
authors.affiliation: Hospital General Universitario Gregorio Marañón, Madrid, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Márquez
authors.affiliation: Hospital Universitario Ramón y Cajal, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Soria
authors.affiliation: Clínica Universitaria de Navarra, Pamplona, Spain.
authors.forename: S M
authors.initials: SM
authors.lastname: Algarra
mesh_terms: D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D019468:Disease Management; D055088:Early Detection of Cancer; D006801:Humans; D008495:Medical Oncology; D008545:Melanoma / Q000175:diagnosis* / Q000628:therapy*; D009367:Neoplasm Staging; D017410:Practice Guidelines as Topic / Q000592:standards*; D011379:Prognosis; D012955:Societies, Medical
keywords: Adjuvant; Immunotherapy; Melanoma; Metastatic; b-raf