title: Predictors and Reference Values of Pulse Wave Velocity in Prepubertal Angolan Children.
abstract: Carotid-femoral pulse wave velocity (PWV) has been used as the gold standard method to estimate arterial stiffness. However, its use in clinical practice is still limited because reference values for specific groups, such as black children, remain unknown. The authors aimed to investigate predictors and to propose preliminary reference values of PWV in this population. Prepubertal schoolchildren (N=157; mean age, 9.36±1.41 year) from Luanda (Angola) with normal blood pressure values and without obesity were included. Mean PWV was 5.73±0.68 m/s, with no difference between the sexes. Univariate regression analysis showed a significant (P<.05) positive correlation between PWV and height, age, body weight, lean body weight, and blood pressure. In multivariate analysis, however, only height remained an independent predictor of PWV [PWV=0.018×height (cm)+3.230]. Curves of PWV percentiles as a function of height are proposed, thus identifying normal PWV in black children.
authors.affiliation: Department of Physiological Sciences, Federal University of Espírito Santo, Espírito Santo, Brazil.|Department of Physiological Sciences, Medical School of the Agostinho Neto University, Luanda, Angola.
authors.forename: Amílcar B T
authors.initials: AB
authors.lastname: Silva
authors.affiliation: Department of Physiological Sciences, Medical School of the Agostinho Neto University, Luanda, Angola.
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Capingana
authors.affiliation: Department of Physiological Sciences, Medical School of the Agostinho Neto University, Luanda, Angola.
authors.forename: Pedro
authors.initials: P
authors.lastname: Magalhães
authors.affiliation: Department of Nutrition, Federal University of Espírito Santo, Espírito Santo, Brazil.
authors.forename: Maria Del Carmen B
authors.initials: Mdel C
authors.lastname: Molina
authors.affiliation: Department of Physiological Sciences, Federal University of Espírito Santo, Espírito Santo, Brazil.
authors.forename: Marcelo P
authors.initials: MP
authors.lastname: Baldo
authors.affiliation: Department of Physiological Sciences, Federal University of Espírito Santo, Espírito Santo, Brazil.
authors.forename: José Geraldo
authors.initials: JG
authors.lastname: Mill
mesh_terms: D000810:Angola; D002339:Carotid Arteries / Q000502:physiology*; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D005263:Femoral Artery / Q000502:physiology*; D006801:Humans; D008297:Male; D063177:Pulse Wave Analysis / Q000379:methods*; D012016:Reference Values; D012044:Regression Analysis