title: Content of bioelements in the lungs and liver in rats with alimentary obesity.
abstract: The synchrotron radiation X-ray fluorescence technique (SRXRF) was applied to the determination of K, Ca, Mn, Fe, Cu, Zn, Se, Br, Rb, and Sr concentrations in the liver and lungs in Wistar rats. The animals in the experiment included (1) healthy rats, (2) rats with alimentary obesity (AO), and (3) rats with alimentary obesity that were being given zinc sulphate with water for a long time (АО+Zn). Each group was divided into two subgroups. The experiment with the first subgroup was terminated with the animals in the state of physiological hunger and subsequent retrieval of liver and lung tissue, while the animals of the second subgroup were sacrificed two hours after ingestion of lard. The rats in physiological hunger manifested intergroup differences in the content of the bioelements (BEs) neither in the liver nor in the lungs. The rats with AO, as compared with the healthy animals, demonstrated in physiological hunger redistribution of inter-element correlations (IECs), which is an indirect reflection of sustained metabolic disorder. Additional zinc in the rats' ration did not affect their body weight and the concentration of the BEs (including zinc) in the liver and the lungs. However, the IECs in the tissues of these animals in physiological hunger also changed. This redistribution differed from that in the rats with AO. The IECs soon after ingestion of lard also changed, which also reflects sustained changes in the metabolism in the animals.
authors.affiliation: Laboratory of Spectroscopy of Inorganic Compounds, Nikolaev Institute of Inorganic Chemistry SB RAS, 3, Acad. Lavrentiev Ave., Novosibirsk 630090, Russia; Faculty of Natural Sciences, Novosibirsk State University, 2 Pirogova Str., Novosibirsk 630090, Russia. Electronic address: valna-t@mail.ru.
authors.forename: V A
authors.initials: VA
authors.lastname: Trunova
authors.affiliation: Laboratory of Spectroscopy of Inorganic Compounds, Nikolaev Institute of Inorganic Chemistry SB RAS, 3, Acad. Lavrentiev Ave., Novosibirsk 630090, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Sidorina
authors.affiliation: Laboratory of Spectroscopy of Inorganic Compounds, Nikolaev Institute of Inorganic Chemistry SB RAS, 3, Acad. Lavrentiev Ave., Novosibirsk 630090, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Zvereva
authors.affiliation: Faculty of Natural Sciences, Novosibirsk State University, 2 Pirogova Str., Novosibirsk 630090, Russia; Laboratory of Clinical Morphology, Institute of Molecular Pathology and Pathomorphology SB RAMS, 2 Timakova Str., Novosibirsk 630060, Russia.
authors.forename: B V
authors.initials: BV
authors.lastname: Churin
authors.affiliation: Laboratory of Functional Morphology of Lymphatic System, Scientific Institution of Clinical and Experimental Lymphology SB RAMS, 2 Timakova Str., Novosibirsk 630060, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Starkova
authors.affiliation: Laboratory 8-2, Budker Institute of Nuclear Physics SB RAS, 11, Acad. Lavrentiev Ave., Novosibirsk 630090, Russia.
authors.forename: D S
authors.initials: DS
authors.lastname: Sorokoletov
mesh_terms: D000818:Animals; D004064:Digestive System / Q000473:pathology*; D008099:Liver / Q000378:metabolism*; D008168:Lung / Q000378:metabolism*; D009765:Obesity / Q000378:metabolism*; D017208:Rats, Wistar; D018709:Statistics, Nonparametric; D014131:Trace Elements / Q000378:metabolism*
chemical_list: D014131:Trace Elements
keywords: Bioelements; Correlations; Liver; Lungs; Obesity; Synchrotron radiation; X-ray fluorescence analysis