title: Prevalence and features of colorectal lesions among Hispanics: A hospital-based study.
abstract: OBJECTIVE
  To evaluate the prevalence and characteristics of colorectal adenoma and carcinoma in an inner city Hispanic population.
  
  
  METHODS
  We reviewed the reports of 1628 Hispanic patients who underwent colonoscopy at Howard University from 2000 to 2010. Advanced adenoma was defined as adenoma ≥ 1 cm in size, adenomas with villous histology, high grade dysplasia and/or invasive cancer. Statistical analysis was performed using χ(2) statistics and t-test.
  
  
  RESULTS
  The median age of the patients was 54 years, 64.2% were females. Polyps were observed in 489 (30.0%) of patients. Adenoma prevalence was 16.8% (n = 273), advanced adenoma 2.4% (n = 39), and colorectal cancer 0.4% (n = 7). Hyperplastic polyps were seen in 6.6% of the cohort (n = 107). Adenomas predominantly exhibited a proximal colonic distribution (53.7%, n = 144); while hyperplastic polyps were mostly located in the distal colon (70%, n = 75). Among 11.7% (n = 191) patients who underwent screening colonoscopy, the prevalence of colorectal lesions was 21.4% adenoma, 2.6% advanced adenoma; and 8.3% hyperplastic polyps.
  
  
  CONCLUSIONS
  Our data showed low colorectal cancer prevalence among Hispanics in the Washington DC area. However, the pre-neoplastic pattern of colonic lesions in Hispanics likely points toward a shift in this population that needs to be monitored closely through large epidemiological studies.
authors.affiliation: Hassan Ashktorab, Adeyinka O Laiyemo, Edward Lee, Marcia Cruz-Correa, Amita Ghuman, Mehdi Nouraie, Hassan Brim, Gastroenterology Division and Cancer Center, Pathology Department, Howard University College of Medicine, Washington, DC 20059, United States.
authors.forename: Hassan
authors.initials: H
authors.lastname: Ashktorab
authors.affiliation: Hassan Ashktorab, Adeyinka O Laiyemo, Edward Lee, Marcia Cruz-Correa, Amita Ghuman, Mehdi Nouraie, Hassan Brim, Gastroenterology Division and Cancer Center, Pathology Department, Howard University College of Medicine, Washington, DC 20059, United States.
authors.forename: Adeyinka O
authors.initials: AO
authors.lastname: Laiyemo
authors.affiliation: Hassan Ashktorab, Adeyinka O Laiyemo, Edward Lee, Marcia Cruz-Correa, Amita Ghuman, Mehdi Nouraie, Hassan Brim, Gastroenterology Division and Cancer Center, Pathology Department, Howard University College of Medicine, Washington, DC 20059, United States.
authors.forename: Edward
authors.initials: E
authors.lastname: Lee
authors.affiliation: Hassan Ashktorab, Adeyinka O Laiyemo, Edward Lee, Marcia Cruz-Correa, Amita Ghuman, Mehdi Nouraie, Hassan Brim, Gastroenterology Division and Cancer Center, Pathology Department, Howard University College of Medicine, Washington, DC 20059, United States.
authors.forename: Marcia
authors.initials: M
authors.lastname: Cruz-Correa
authors.affiliation: Hassan Ashktorab, Adeyinka O Laiyemo, Edward Lee, Marcia Cruz-Correa, Amita Ghuman, Mehdi Nouraie, Hassan Brim, Gastroenterology Division and Cancer Center, Pathology Department, Howard University College of Medicine, Washington, DC 20059, United States.
authors.forename: Amita
authors.initials: A
authors.lastname: Ghuman
authors.affiliation: Hassan Ashktorab, Adeyinka O Laiyemo, Edward Lee, Marcia Cruz-Correa, Amita Ghuman, Mehdi Nouraie, Hassan Brim, Gastroenterology Division and Cancer Center, Pathology Department, Howard University College of Medicine, Washington, DC 20059, United States.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Nouraie
authors.affiliation: Hassan Ashktorab, Adeyinka O Laiyemo, Edward Lee, Marcia Cruz-Correa, Amita Ghuman, Mehdi Nouraie, Hassan Brim, Gastroenterology Division and Cancer Center, Pathology Department, Howard University College of Medicine, Washington, DC 20059, United States.
authors.forename: Hassan
authors.initials: H
authors.lastname: Brim
mesh_terms: D018256:Adenomatous Polyps / Q000208:ethnology* / Q000473:pathology; D002277:Carcinoma / Q000208:ethnology* / Q000473:pathology; D016009:Chi-Square Distribution; D003111:Colonic Polyps / Q000208:ethnology* / Q000473:pathology; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000208:ethnology* / Q000473:pathology; D004219:District of Columbia / Q000453:epidemiology; D005260:Female; D006630:Hispanic or Latino; D006785:Hospitals, University; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D011230:Precancerous Conditions / Q000208:ethnology* / Q000473:pathology; D015995:Prevalence; D012189:Retrospective Studies; D013997:Time Factors; D014504:Urban Health
keywords: Adenoma; Carcinoma; Colon; Hispanics; Rectum