title: Encoding of frequency-modulation (FM) rates in human auditory cortex.
abstract: Frequency-modulated sounds play an important role in our daily social life. However, it currently remains unclear whether frequency modulation rates affect neural activity in the human auditory cortex. In the present study, using magnetoencephalography, we investigated the auditory evoked N1m and sustained field responses elicited by temporally repeated and superimposed frequency-modulated sweeps that were matched in the spectral domain, but differed in frequency modulation rates (1, 4, 16, and 64 octaves per sec). The results obtained demonstrated that the higher rate frequency-modulated sweeps elicited the smaller N1m and the larger sustained field responses. Frequency modulation rate had a significant impact on the human brain responses, thereby providing a key for disentangling a series of natural frequency-modulated sounds such as speech and music.
authors.affiliation: Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan.|Department of Physiological Sciences, School of Life Science, SOKENDAI (The Graduate University for Advanced Studies), Hayama, Japan.
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Okamoto
authors.affiliation: Department of Integrative Physiology, National Institute for Physiological Sciences, Okazaki, Japan.|Department of Physiological Sciences, School of Life Science, SOKENDAI (The Graduate University for Advanced Studies), Hayama, Japan.
authors.forename: Ryusuke
authors.initials: R
authors.lastname: Kakigi
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods*; D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001303:Auditory Cortex / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D001309:Auditory Threshold / Q000502:physiology; D001921:Brain / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D009146:Music; D013016:Sound; D013060:Speech / Q000502:physiology; D013997:Time Factors; D055815:Young Adult