title: Designing Better, Not Just Bigger, Multicenter Critical Care Trials.
authors.affiliation: University of Pennsylvania, Philadelphia, PennsylvaniaCentre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: Michael O
authors.initials: MO
authors.lastname: Harhay
authors.forename: James A
authors.initials: JA
authors.lastname: Russell
mesh_terms: D003422:Critical Care / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D016032:Randomized Controlled Trials as Topic / Q000379:methods* / Q000401:mortality*