title: ASSOCIATION BETWEEN DAILY SITTING TIME AND PREVALENT METABOLIC SYNDROME IN AN ADULT WORKING POPULATION: THE AWHS COHORT.
abstract: OBJECTIVE
  the aim of this analysis was to measure the association between daily sitting time and prevalent metabolic syndrome, independently of the physical activity performed.
  
  
  METHODS
  the Aragon Workers' Health Study cohort consists of 5 865 participants from which a sample of 1 415 male participants (40-55 years old) with completed data at baseline was selected. Sitting time and physical activity were assessed by validated questionnaires, and the socio-demographic, clinical and biochemical covariates needed to diagnose metabolic syndrome were collected as part of the study protocols. Metabolic syndrome was defined according to the modified National Cholesterol Education Program - Adult Treatment Panel III. Multiple linear and logistic regression models were carried out to quantify this association using sitting time categorized into tertiles.
  
  
  RESULTS
  mean sitting time was 5.78 ± 1.72 h/day, and the prevalence of metabolic syndrome was 19.2%. Comparing participants in the highest (> 6.57 h/day) versus lowest (1.85-4.57 h/day) tertile of sitting time, a positive association was observed for metabolic syndrome (OR 1.77, 95%CI: 1.25-2.49) and triglyceride (OR 1.70, 95%CI: 1.30-2.24), HDL-cholesterol (OR 1.65, 95%CI: 1.06-2.58), waist circumference (OR 1.57, 95%CI: 1.17-2.11) and fasting blood glucose (OR 1.35, 95%CI: 1.03-1.77) criteria, adjusting the level of physical activity.
  
  
  CONCLUSIONS
  higher sitting time is associated with an increased prevalence of metabolic syndrome independently of physical activity performed. These results could be useful to carry out effective strategies for cardiovascular health promotion especially in workplaces.
authors.affiliation: Cardiovascular Prevention Unit, Instituto Aragonés de Ciencias de la Salud (IACS), Fundación Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain. Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Zaragoza, Spain.. bmorenof.iacs@aragon.es.
authors.forename: Belén
authors.initials: B
authors.lastname: Moreno-Franco
authors.affiliation: Department of Epidemiology, Atherothrombosis and Cardiovascular Imaging, Fundación Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. School of Nutrition Science and Policy, Tufts University. Boston, Massachusetts.. bmorenof.iacs@aragon.es.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Peñalvo
authors.affiliation: CIBER, Epidemiology and Public Health, (CIBERESP), Madrid, Spain.. bmorenof.iacs@aragon.es.
authors.forename: Eva María
authors.initials: EM
authors.lastname: Andrés-Esteban
authors.affiliation: Department of Microbiology, Preventive Medicine and Public Health, University of Zaragoza, Zaragoza, Spain.. bmorenof.iacs@aragon.es.
authors.forename: Sara
authors.initials: S
authors.lastname: Malo
authors.affiliation: Primary Care Pharmacy Service, Aragon Health Service, Zaragoza, Spain.. bmorenof.iacs@aragon.es.
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: Lallana
authors.affiliation: Cardiovascular Prevention Unit, Instituto Aragonés de Ciencias de la Salud (IACS), Fundación Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain. Department of Medicine, Psychiatry and Dermatology, University of Zaragoza, Zaragoza, Spain.. bmorenof.iacs@aragon.es.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Casasnovas
authors.affiliation: Cardiovascular Prevention Unit, Instituto Aragonés de Ciencias de la Salud (IACS), Fundación Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.. bmorenof.iacs@aragon.es.
authors.forename: Montserrat
authors.initials: M
authors.lastname: León-Latre
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D015444:Exercise; D006801:Humans; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012959:Socioeconomic Factors; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires