title: Iatrogenic Necrolytic Migratory Erythema in an Infant with Congenital Hyperinsulinism.
abstract: Necrolytic migratory erythema (NME) is a rare cutaneous finding characterized by painful, pruritic, scaly red patches and plaques, bullae, and superficial erosions. Typically NME is a paraneoplastic phenomenon associated with glucagonoma. We report the exceptional case of an infant who developed iatrogenic NME arising secondary to glucagon therapy for congenital hyperinsulinism.
authors.affiliation: Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri.
authors.forename: Carrie C
authors.initials: CC
authors.lastname: Coughlin
authors.affiliation: Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
authors.forename: Sani M
authors.initials: SM
authors.lastname: Roy
authors.affiliation: Department of Dermatology, Rush University Medical Center, Chicago, Illinois.
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Arkin
authors.affiliation: Division of Pediatric General, Thoracic and Fetal Surgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
authors.forename: N Scott
authors.initials: NS
authors.lastname: Adzick
authors.affiliation: Section of Pediatric Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.|Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.|Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Albert C
authors.initials: AC
authors.lastname: Yan
authors.affiliation: Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.|Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Diva D
authors.initials: DD
authors.lastname: De León
authors.affiliation: Division of Pediatric General, Thoracic and Fetal Surgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.|Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.|Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Adam I
authors.initials: AI
authors.lastname: Rubin
mesh_terms: D044903:Congenital Hyperinsulinism / Q000188:drug therapy*; D005260:Female; D005934:Glucagon / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007049:Iatrogenic Disease; D007223:Infant; D058568:Necrolytic Migratory Erythema / Q000139:chemically induced* / Q000175:diagnosis; D012867:Skin / Q000473:pathology*
chemical_list: D005934:Glucagon