title: VALIDATION AND COMPARISON OF EQ-5D-3L AND SF-6D INSTRUMENTS IN A SPANISH PARKINSON´S DISEASE POPULATION SAMPLE.
abstract: BACKGROUND
  generic, preference-based Health- Related Quality of Life instruments are receiving growing attention in health-care decision-making process. In spite of this, to our knowledge, EQ-5D and SF-6D have never been compared in a Parkinson´s disease population sample.
  
  
  OBJECTIVE
  the aim of this paper was to assess the psychometric properties of both instruments in a Spanish PD population sample.
  
  
  METHODS
  a total sample of 133 patients were interviewed using EQ-5D-3L and SF-6D. The validity, level of agreement and sensitivity of both instruments were computed and then compared. The Spanish tariff has been used in both instruments.
  
  
  RESULTS
  utilities of EQ-5D-3L and SF-6D have shown a strong correlation (r >0.50 and p<0.001) with the summary score of the PDQ-8 and the EQ-VAS score. Significant differences were observed in the stages III-IV of the Hoehn & Yahr stage. SF-6D had 51% higher efficiency than EQ-5D at detecting differences in symptoms severity.
  
  
  CONCLUSIONS
  both EQ-5D-3L and SF-6D seem to be adequate generic Health-Related Quality of Life measures in terms of validity and sensitivity.
  
  
  CONCLUSIONS
  EQ-5D-3L presents greater ceiling and floor effects than the SF-6D instrument in this sample. Besides, the instrument SF-6D was better at detecting changes in symptoms severity compared with EQ-5D-3L.
authors.affiliation: Department of Applied Economics, Faculty of Economics and Business, University of Murcia, Murcia, Spain. Department of Economics, Faculty of Economics and Business, University of Extremadura, Badajoz, Spain.. miguelgarciagordillo@gmail.com.
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Garcia-Gordillo
authors.affiliation: Department of Sport and Exercise Science, Faculty of Science, The University of Auckland, Auckland, New Zealand.. b.delpozocruz@auckland.ac.nz.
authors.forename: B
authors.initials: B
authors.lastname: Del Pozo-Cruz
authors.affiliation: Department of Applied Economics, Faculty of Economics and Business, University of Murcia, Murcia, Spain. Faculty of Sport Science, University of Extremadura, Cáceres, Spain.. jadssal@unex.es.
authors.forename: J C
authors.initials: JC
authors.lastname: Adsuar
authors.affiliation: Department of Economics, Faculty of Economics and Business, University of Extremadura, Badajoz, Spain.. jmcordero@unex.es.
authors.forename: J M
authors.initials: JM
authors.lastname: Cordero-Ferrera
authors.affiliation: Department of Applied Economics, Faculty of Economics and Business, University of Murcia, Murcia, Spain.. dionisos@um.es.
authors.forename: J M
authors.initials: JM
authors.lastname: Abellan-Perpiñan
authors.affiliation: Department of Applied Economics, Faculty of Economics and Business, University of Murcia, Murcia, Spain.. fernando@um.es.
authors.forename: F I
authors.initials: FI
authors.lastname: Sanchez-Martinez
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis* / Q000523:psychology*; D011788:Quality of Life; D012016:Reference Values; D015203:Reproducibility of Results; D013030:Spain; D011795:Surveys and Questionnaires