title: A facile approach toward multi-functional polyurethane/polyethersulfone composite membranes for versatile applications.
abstract: The complex synthesis through multistep reactions and tedious purifications based on different monomers or macromolecules limits the practical applications of functional polymers. Herein, a facile approach toward a series of functional polyurethanes (PUs) is designed for versatile biological applications within fewer step reactions under mild conditions. The tertiary amino groups in the PU are converted into zwitterions or quaternary ammonium salt via simple one-step synthesis, and then used to prepare PU/polyethersulfone composite membranes. The composite membrane with tertiary amine groups exhibits significant adsorption capability to anionic dye Congo red (CR) and toxin bilirubin. The membrane bearing zwitterionic PU displays excellent blood compatibility; while which with quaternary ammonium salts has antibacterial property. Furthermore, carboxybetaine-functional composite membrane is exploited to bear Ag nanoparticles to endow with dual functions of antibacterial and antifouling properties. This work demonstrates the potential of PUs as readily available, multi-functional, and easy-to-use materials for biological applications.
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China.
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China.
authors.forename: Tao
authors.initials: T
authors.lastname: Xiang
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China. Electronic address: weifeng@kth.se.
authors.forename: Wei-Feng
authors.initials: WF
authors.lastname: Zhao
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, People's Republic of China; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, People's Republic of China. Electronic address: zhaochsh70@163.com.
authors.forename: Chang-Sheng
authors.initials: CS
authors.lastname: Zhao
mesh_terms: D000327:Adsorption; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D008567:Membranes, Artificial; D010314:Partial Thromboplastin Time; D010973:Platelet Adhesiveness / Q000187:drug effects; D011108:Polymers / Q000737:chemistry*; D011140:Polyurethanes / Q000737:chemistry*; D013450:Sulfones / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011108:Polymers; D011140:Polyurethanes; D013450:Sulfones; C022840:polyether sulfone
keywords: Adsorption capacity; Antibacterial property; Blood compatibility; Polyethersulfone; Polyurethane