title: [NEW APPROACHES TO THE EARLY DIAGNOSIS OF INTRAUTERINE VIRAL INFECTIONS IN NEWBORNS].
abstract: The importance of intrauterine viral infections in newborns pathology remain incompletely understood, as there is the problem of early verification of the etiologic pathogen. The aim of the study was to develop diagnostic criteria for intrauterine viral infections by introducing rapid diagnostic methods, the study of perinatal factors, medical history, clinical course and laboratory data. Clinical and laboratory examination 834 mothers and their newborn patients with suspected intrauterine infection. We observed 224 children with verified intrauterine viral infection. Studied the history of perinatal risk factors, clinical features and laboratory data. Studies have shown that the predominant form of mixed infections (85.7%). On the basis of statistical methods developed diagnostic criteria and algorithm of differential diagnosis of all possible variants of infection. Testing diagnostic algorithm has shown high reliability of diagnostic criteria, which allows recommend them for clinical use.
authors.affiliation: Zaporozhye Medical Academy of Post-Graduated Education, Ukraine.
authors.forename: I
authors.initials: I
authors.lastname: Redko
mesh_terms: D001424:Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology / Q000821:virology; D002846:Chromatography, Affinity / Q000295:instrumentation / Q000379:methods; D060085:Coinfection; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D005260:Female; D005312:Fetal Blood / Q000382:microbiology / Q000821:virology; D005333:Fetus; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric; D058889:Molecular Typing / Q000295:instrumentation / Q000379:methods*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000382:microbiology / Q000821:virology; D012307:Risk Factors; D014599:Uterus / Q000382:microbiology / Q000821:virology; D014777:Virus Diseases / Q000175:diagnosis* / Q000382:microbiology / Q000821:virology