title: From DNA to catalysis: a thymine-acetate ligated non-heme iron(III) catalyst for oxidative activation of aliphatic C-H bonds.
abstract: A non-heme, iron(III)/THA(thymine-1-acetate) catalyst together with H2O2 as an oxidant is efficient in oxidative C-H activation of alkanes. Although having a higher preference for tertiary C-H bonds, the catalyst also oxidizes aliphatic secondary C-H bonds into carbonyl compounds with good to excellent conversions. Based on the site selectivity of the catalyst and our mechanistic studies the reaction proceeds via an Fe-oxo species without long lived carbon centered radicals.
authors.affiliation: Department of Chemistry, University of Helsinki, A. I. Virtasen Aukio 1, P.O. Box 55, 00014 University of Helsinki, Finland. timo.repo@helsinki.fi.
authors.forename: Afnan
authors.initials: A
authors.lastname: Al-hunaiti
authors.affiliation: Department of Chemistry, University of Helsinki, A. I. Virtasen Aukio 1, P.O. Box 55, 00014 University of Helsinki, Finland. timo.repo@helsinki.fi.
authors.forename: Minnä
authors.initials: M
authors.lastname: Räisänen
authors.affiliation: Department of Chemistry, University of Helsinki, A. I. Virtasen Aukio 1, P.O. Box 55, 00014 University of Helsinki, Finland. timo.repo@helsinki.fi.
authors.forename: Timo
authors.initials: T
authors.lastname: Repo
mesh_terms: D000085:Acetates / Q000737:chemistry*; D000473:Alkanes / Q000737:chemistry*; D002384:Catalysis; D004247:DNA / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D006418:Heme / Q000737:chemistry*; D006860:Hydrogen Bonding; D006861:Hydrogen Peroxide / Q000737:chemistry*; D010084:Oxidation-Reduction; D013941:Thymine / Q000737:chemistry*
chemical_list: D000085:Acetates; D000473:Alkanes; D005290:Ferric Compounds; D006418:Heme; D004247:DNA; D006861:Hydrogen Peroxide; D013941:Thymine