title: Training Status as a Marker of the Relationship between Nitric Oxide, Oxidative Stress, and Blood Pressure in Older Adult Women.
abstract: The purpose of this study was to evaluate the influence of functional fitness and oxidative capacity on the nitric oxide concentration associated with hemodynamic control in older adult women. The sample consisted of 134 women (65.73 ± 6.14 years old). All subjects underwent a physical examination to assess body mass index, waist-hip ratio, body fat measurement by dual energy X-ray absorptiometry, and blood pressure (BP). Training status (TS) was evaluated by indirect determination of maximal oxygen uptake by a treadmill test using Balke protocol modified for older adults. Functional fitness was also evaluated through a "Functional Fitness Battery Test" to determine the general fitness functional index (GFFI). All participants were separated according to the functional fitness (TS1, very weak and weak; TS2, regular; TS3, good and very good). Plasma blood samples were used to evaluate prooxidant and antioxidant activity and nitrite and nitrate concentrations. The general results of this study showed that good levels of TS were related to lower levels of lipoperoxidation and protein damage, higher levels of antioxidant, and higher concentration of nitrite and nitrate. This combination may be responsible for the lower levels of BP in subjects with better TS.
authors.affiliation: Ribeirao Preto Medical School, University of Sao Paulo (USP), Avenida Bandeirantes 3900, 14049-900 Ribeirao Preto, SP, Brazil.
authors.forename: André Mourão
authors.initials: AM
authors.lastname: Jacomini
authors.affiliation: Ribeirao Preto Medical School, University of Sao Paulo (USP), Avenida Bandeirantes 3900, 14049-900 Ribeirao Preto, SP, Brazil.
authors.forename: Hugo Celso Dutra
authors.initials: HC
authors.lastname: de Souza
authors.affiliation: Translational Physiology Laboratory, Universidade Nove de Julho (UNINOVE), Rua Vergueiro 235/249, Liberdade, 01504-001 Sao Paulo, SP, Brazil.
authors.forename: Danielle da Silva
authors.initials: Dda S
authors.lastname: Dias
authors.affiliation: Translational Physiology Laboratory, Universidade Nove de Julho (UNINOVE), Rua Vergueiro 235/249, Liberdade, 01504-001 Sao Paulo, SP, Brazil.
authors.forename: Janaina de Oliveira
authors.initials: Jde O
authors.lastname: Brito
authors.affiliation: Ribeirao Preto Medical School, University of Sao Paulo (USP), Avenida Bandeirantes 3900, 14049-900 Ribeirao Preto, SP, Brazil.
authors.forename: Lucas Cezar
authors.initials: LC
authors.lastname: Pinheiro
authors.affiliation: Ribeirao Preto Medical School, University of Sao Paulo (USP), Avenida Bandeirantes 3900, 14049-900 Ribeirao Preto, SP, Brazil.
authors.forename: Anderson Bernardino
authors.initials: AB
authors.lastname: da Silva
authors.affiliation: Ribeirao Preto Medical School, University of Sao Paulo (USP), Avenida Bandeirantes 3900, 14049-900 Ribeirao Preto, SP, Brazil.
authors.forename: Roberta Fernanda
authors.initials: RF
authors.lastname: da Silva
authors.affiliation: School of Nursing of Ribeirao Preto, University of Sao Paulo (USP), Avenida Bandeirantes 3900, 14040-902 Ribeirao Preto, SP, Brazil.
authors.forename: Atila Alexandre
authors.initials: AA
authors.lastname: Trapé
authors.affiliation: Translational Physiology Laboratory, Universidade Nove de Julho (UNINOVE), Rua Vergueiro 235/249, Liberdade, 01504-001 Sao Paulo, SP, Brazil.
authors.forename: Kátia
authors.initials: K
authors.lastname: De Angelis
authors.affiliation: Ribeirao Preto Medical School, University of Sao Paulo (USP), Avenida Bandeirantes 3900, 14049-900 Ribeirao Preto, SP, Brazil.
authors.forename: José Eduardo
authors.initials: JE
authors.lastname: Tanus-Santos
authors.affiliation: Department of Physical Education, Universidade Estadual Paulista (UNESP), Avenida Engenheiro Luiz Edmundo Carrijo Coube, 14-01, Bairro Vargem Limpa, 17033-360 Bauru, SP, Brazil.
authors.forename: Sandra Lia
authors.initials: SL
authors.lastname: do Amaral
authors.affiliation: Department of Physical Education, Universidade Estadual Paulista (UNESP), Avenida Engenheiro Luiz Edmundo Carrijo Coube, 14-01, Bairro Vargem Limpa, 17033-360 Bauru, SP, Brazil.
authors.forename: Anderson Saranz
authors.initials: AS
authors.lastname: Zago
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D015992:Body Mass Index; D005080:Exercise Test; D005260:Female; D006801:Humans; D008875:Middle Aged; D009569:Nitric Oxide / Q000032:analysis*; D018384:Oxidative Stress; D010101:Oxygen Consumption; D013482:Superoxide Dismutase / Q000378:metabolism; D049629:Waist-Hip Ratio
chemical_list: D009569:Nitric Oxide; D013482:Superoxide Dismutase