title: Dermoscopy Pattern, Histopathology and Immunophenotype of Primary Cutaneous B-Cell Lymphoma Presenting as a Solitary Skin Nodule.
abstract: OBJECTIVE
  To date, no dermoscopic features have been described for the diagnosis of primary cutaneous B-cell lymphoma (PCBCL). This tool might be helpful for the clinical differential diagnosis in the context of single erythematous nodules of the skin.
  
  
  METHODS
  Ten cases of PCBCL, presenting clinically as solitary red/pinkish nodules, were retrospectively retrieved. Patient data were collected along with dermoscopic and histopathological features of each lesion. Most lesions (9/10) showed white circles with a salmon-colored background/area (6 lesions), scales (7 lesions), arborizing vessels (5 lesions) or a polymorphous vascular pattern (2 lesions). Histology revealed a cutaneous marginal zone lymphoma in 6 lesions, a follicle center lymphoma in 2 lesions and a diffuse large B-cell lymphoma in 2 lesions.
  
  
  CONCLUSIONS
  Dermoscopic examination may be helpful for improving the clinical recognition of PCBCL although skin biopsy remains mandatory.
authors.affiliation: Pathology Section, Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Mascolo
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Piccolo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Argenziano
authors.forename: Claudia
authors.initials: C
authors.lastname: Costa
authors.forename: Maurizio
authors.initials: M
authors.lastname: Lo Presti
authors.forename: Gaetano
authors.initials: G
authors.lastname: De Rosa
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Scalvenzi
authors.forename: Stefania
authors.initials: S
authors.lastname: Staibano
mesh_terms: D000328:Adult; D000368:Aged; D046169:Dermoscopy; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging* / Q000473:pathology; D008224:Lymphoma, Follicular / Q000000981:diagnostic imaging* / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D055815:Young Adult