title: Monitoring bladder compliance using end filling detrusor pressure: Clinical results and related factors.
abstract: OBJECTIVE
  To assess the clinical significance of low compliance bladder (LCB) in women with lower urinary tract symptoms.
  
  
  METHODS
  Medical records of 1490 women undergoing videourodynamic studies (VUSs) were reviewed. Comprehensive medical histories, physical examinations, bladder diaries, and results of multichannel VUS were analyzed. This study adopted an end filling detrusor pressure (EFP) greater than 20 cmH2O to define LCB.
  
  
  RESULTS
  Among the study patients (n = 1490), 9.1% were diagnosed with LCB using a cutoff value of 17.5 cmH2O, which had a sensitivity and specificity of 89% and 92.7%, respectively. Results of multivariate analysis indicated that age (p = 0.005), maximum cystometric capacity (MCC; p = 0.002), detrusor overactivity (DO; p = 0.001), pelvic organ prolapse (POP; p = 0.018), recurrent urinary tract infection (p = 0.001), and radical abdominal hysterectomy (RAH; p < 0.001) as independent prognostic factors. Furthermore, our study results indicate that the MCC, urinary tract infection, and a history of RAH have a positive correlation with LCB, whereas, age, POP, and DO have a negative correlation with LCB.
  
  
  CONCLUSIONS
  Our idea using EFP (≥17.5 cmH2O) for screening women with LCB is feasible for clinical use.
authors.affiliation: University of Chang Gung School of Medicine, Taoyuan, Taiwan.
authors.forename: Jin-Yi
authors.initials: JY
authors.lastname: Liao
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Lin-Kou Branch and University of Chang Gung School of Medicine, Taoyuan, Taiwan.
authors.forename: Yi-Hao
authors.initials: YH
authors.lastname: Lin
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Lin-Kou Branch and University of Chang Gung School of Medicine, Taoyuan, Taiwan.
authors.forename: Ching-Chung
authors.initials: CC
authors.lastname: Liang
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Lin-Kou Branch and University of Chang Gung School of Medicine, Taoyuan, Taiwan.
authors.forename: Wu-Chiao
authors.initials: WC
authors.lastname: Hsieh
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Lin-Kou Branch and University of Chang Gung School of Medicine, Taoyuan, Taiwan.
authors.forename: She-Jane
authors.initials: SJ
authors.lastname: Lee
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Lin-Kou Branch and University of Chang Gung School of Medicine, Taoyuan, Taiwan. Electronic address: 3g7330@yahoo.com.tw.
authors.forename: Ling-Hong
authors.initials: LH
authors.lastname: Tseng
mesh_terms: D000367:Age Factors; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000503:physiopathology; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D001743:Urinary Bladder / Q000503:physiopathology*; D053201:Urinary Bladder, Overactive / Q000503:physiopathology; D014552:Urinary Tract Infections / Q000503:physiopathology; D014563:Urodynamics / Q000502:physiology*
keywords: low compliance bladder; lower urinary tract symptoms; urinary bladder; urodynamics