title: [Diffusion Weighted Magnetic Resonance Imaging and its Application in Ophthalmology].
abstract: The value of diffusion-weighted magnet resonance imaging (DWI-MRI) has been demonstrated for an ever growing range of clinical indications. DWI is sensitive to the diffusion of water molecules and probes their random displacement within tissue. DWI provides both qualitative and quantitative information on tissue characteristics, e.g. tissue cellularity. This review provides an overview of diffusion-weighted imaging and its emerging applications in ophthalmology. The basic physics and technical foundations of DWI are introduced. The emerging applications of DWI are surveyed, particularly in diseases of the eye, orbit and optical nerve.
authors.affiliation: Core Facility Multimodale Kleintierbildgebung, Universitätsmedizin Rostock.
authors.forename: T
authors.initials: T
authors.lastname: Lindner
authors.affiliation: Institut für Diagnostische Radiologie und Neuroradiologie, Universitätsmedizin Greifswald.
authors.forename: S
authors.initials: S
authors.lastname: Langner
authors.affiliation: Berlin Ultrahigh Field Facility (B. U. F. F.), Max-Delbrück-Zentrum für Molekulare Medizin in der Helmholtz-Gemeinschaft, Berlin.
authors.forename: K
authors.initials: K
authors.lastname: Paul
authors.affiliation: Berlin Ultrahigh Field Facility (B. U. F. F.), Max-Delbrück-Zentrum für Molekulare Medizin in der Helmholtz-Gemeinschaft, Berlin.
authors.forename: A
authors.initials: A
authors.lastname: Pohlmann
authors.affiliation: Institut für Diagnostische Radiologie und Neuroradiologie, Universitätsmedizin Greifswald.
authors.forename: S
authors.initials: S
authors.lastname: Hadlich
authors.affiliation: Berlin Ultrahigh Field Facility (B. U. F. F.), Max-Delbrück-Zentrum für Molekulare Medizin in der Helmholtz-Gemeinschaft, Berlin.
authors.forename: T
authors.initials: T
authors.lastname: Niendorf
authors.affiliation: Universitätsaugenklinik, Universitätsmedizin Rostock.
authors.forename: A
authors.initials: A
authors.lastname: Jünemann
authors.affiliation: Universitätsaugenklinik, Universitätsmedizin Rostock.
authors.forename: R F
authors.initials: RF
authors.lastname: Guthoff
authors.affiliation: Universitätsaugenklinik, Universitätsmedizin Rostock.
authors.forename: O
authors.initials: O
authors.lastname: Stachs
mesh_terms: D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005128:Eye Diseases / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D009916:Orbital Diseases / Q000473:pathology*