title: Detection of Transient Intermediates Generated from Subsite Analogues of [FeFe] Hydrogenases.
abstract: This article reviews the application of transient techniques in the elucidation of electron, proton, and photon chemistry related to the catalytic subsite of [FeFe] hydrogenase from the perspective of research in this area carried out at the UEA and Strathclyde laboratories. The detection of mixed-valence states, bridging CO intermediates, paramagnetic hydrides, and coordinatively unsaturated species has both informed understanding of biological catalysis and stimulated the search for stable analogues of key structural motifs likely involved in turnover states.
authors.affiliation: Department of Physics, University of Strathclyde , SUPA, Glasgow G4 0NG, United Kingdom.
authors.forename: Neil T
authors.initials: NT
authors.lastname: Hunt
authors.affiliation: Energy Materials Laboratory, School of Chemistry, University of East Anglia (UEA) , Norwich Research Park, Norwich NR4 7TJ, United Kingdom.
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Wright
authors.affiliation: Energy Materials Laboratory, School of Chemistry, University of East Anglia (UEA) , Norwich Research Park, Norwich NR4 7TJ, United Kingdom.
authors.forename: Christopher
authors.initials: C
authors.lastname: Pickett
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D004563:Electrochemistry; D006864:Hydrogenase / Q000737:chemistry*; D007506:Iron-Sulfur Proteins / Q000737:chemistry*; D011522:Protons; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D007506:Iron-Sulfur Proteins; D011522:Protons; C118830:iron hydrogenase; D006864:Hydrogenase