title: Long-term Bone Remodeling in HA-coated Stems: A Radiographic Review of 208 Total Hip Arthroplasties (THAs) with 15 to 20 Years Follow-up.
abstract: We present a prospective study focused on radiographic long-term outcomes and bone remodeling at a mean of 17.0 years (range: 15 to 20) in 208 cementless fully HA-coated femoral stems (Corail, DePuy International Ltd, Leeds, UK). Total hip replacements in this study were performed by three members of the surgeon design group between 1986 and 1991. Radiographic evaluation focused on periprosthetic osteolysis, bone remodeling, osseous integration, subsidence, metaphyseal or diaphyseal load transfer, and femoral stress shielding. The radiographs were digitized and examined with contrast-enhancing software for analysis of the trabecular architecture. Radiographic signs of aseptic stem loosening were visible in two cases (1%). Three stems (1.4%) showed metaphyseal periprosthetic osteolysis in four of seven Gruen zones associated with eccentric polyethylene wear awaiting metaphyseal bone grafting and cup liner exchange. One stem (0.5%) was revised due to infection. No stem altered in varus or valgus alignment more than two degrees, and mean subsidence was 0.1 mm (range: 0 to 2 mm) after a mean of 17.0 years. A total of 5 stems (2.4%) required or are awaiting revision surgery. Trabecular orientation and micro-anatomy suggested main proximal load-transfer patterns in all except 3 cases (98.6%). Combined metaphyseal and diaphyseal osseointegration and bone remodeling were visible in 100 stems (48%). Diaphyseal stress shielding and cortical thickening were observed in 3 stems (1.4%). Other radiographic features are discussed in depth. This long-term study of 208 fully HA-coated Corail stems showed satisfactory osseointegration and fixation in 203 cases (97.6%) after a mean of 17.0 years follow-up. Stem failures were associated with extreme eccentric polyethylene wear.
authors.affiliation: OrthoBoldt AG, Guemligen, Switzerland.
authors.forename: Jens G
authors.initials: JG
authors.lastname: Boldt
authors.affiliation: Artro Institute, Lyon, France.
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Cartillier
authors.affiliation: Artro Institute, Annecy le Vieux, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Machenaud
authors.affiliation: Artro Institute, Annecy le Vieux, France.
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Vidalain
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000379:methods / Q000706:statistics & numerical data*; D016723:Bone Remodeling / Q000502:physiology*; D020099:Coated Materials, Biocompatible / Q000627:therapeutic use*; D017886:Durapatite / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006621:Hip Joint / Q000000981:diagnostic imaging* / Q000601:surgery; D006622:Hip Prosthesis / Q000706:statistics & numerical data*; D006801:Humans; D010014:Osteolysis; D011446:Prospective Studies; D011475:Prosthesis Failure; D011859:Radiography; D016896:Treatment Outcome
chemical_list: D020099:Coated Materials, Biocompatible; D017886:Durapatite