title: Clinical parameters related to metamorphopsia outcome in patients with resolved central serous chorioretinopathy using M-CHARTS: retrospective cohort study.
abstract: BACKGROUND
  The purpose of this study was to determine the clinical parameters related to metamorphopsia outcome in patients with resolved central serous chorioretinopathy (CSCR).
  
  
  METHODS
  The charts of 36 eyes with resolved CSCR were retrospectively reviewed. We measured metamorphopsia using M-CHARTS after resolution of serous retinal detachment. We analyzed the relationship between metamorphopsia outcome and clinical parameters including age, visual acuity, chronicity of CSCR, symptom duration and several spectral-domain optical coherence tomography findings using univariate and multivariate forward logistic regression analyses.
  
  
  RESULTS
  The M-CHARTS detected metamorphopsia in 19 eyes (52.8 %). In the univariate analysis, the eyes with metamorphopsia were, relative to those without metamorphopsia, significantly associated with a greater proportion of chronic-recurrent CSCR, initial and final irregularities of retinal pigment epithelium, longer symptom duration, thinner final thickness of central fovea and outer nuclear layer, and final disruption of external limiting membrane (ELM), photoreceptor inner and outer segment junction and cone outer segment tip line (P = 0.003, 0.037, 0.019, 0.003, 0.013, 0.015, <0.001, 0. 012 and 0.002, respectively). However, in the multivariate analysis, chronic-recurrent CSCR (OR 22.5, P = 0.019) and final disrupted ELM (OR 82.6, P = 0.004) were the independent clinical parameters related to poor metamorphopsia outcome.
  
  
  CONCLUSIONS
  Residual metamorphopsia was detected using M-CHARTS in about half of patients (52.8 %) with resolved CSCR. Chronic-recurrent CSCR and final disrupted ELM were the independent clinical parameters related to poor metamorphopsia outcome in patients with resolved CSCR.
authors.affiliation: Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University, Singil-ro 1, Yeongdeungpo-gu, 150-950, Seoul, Korea. bsh209@naver.com.
authors.forename: Seokhyun
authors.initials: S
authors.lastname: Bae
authors.affiliation: Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University, Singil-ro 1, Yeongdeungpo-gu, 150-950, Seoul, Korea. kangajis15@gmail.com.
authors.forename: Kiwon
authors.initials: K
authors.lastname: Jin
authors.affiliation: Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University, Singil-ro 1, Yeongdeungpo-gu, 150-950, Seoul, Korea. ophkim@hallym.or.kr.
authors.forename: Hakyoung
authors.initials: H
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University, Singil-ro 1, Yeongdeungpo-gu, 150-950, Seoul, Korea. sohyun.bae.md@gmail.com.
authors.forename: So Hyun
authors.initials: SH
authors.lastname: Bae
mesh_terms: D000328:Adult; D000368:Aged; D056833:Central Serous Chorioretinopathy / Q000175:diagnosis* / Q000503:physiopathology; D002908:Chronic Disease; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012163:Retinal Detachment / Q000175:diagnosis / Q000503:physiopathology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014786:Vision Disorders / Q000175:diagnosis* / Q000503:physiopathology; D014787:Vision Tests / Q000295:instrumentation*; D014792:Visual Acuity / Q000502:physiology*