title: [The early clinical efficacy of allogeneic corneal lens inlays in correction of hyperopia].
abstract: OBJECTIVE
  To evaluate the safety, effectiveness and predictability of allogeneic corneal lens inlays in correcting hyperopia.
  
  
  METHODS
  In this case series study. Twenty-one hyperopic patients (37 eyes) received allogeneic corneal lens inlays. The range of preoperative spherical equivalent was 3.25 to 10.00 D, and the mean value was (6.84 ± 2.79)D. All the cases were followed up for 3 months. Uncorrected and best corrected visual acuity and refraction were compared before and after operation. Corneal topography and optical coherence tomography were performed. Ocular response analyzer was used to evaluate the shifts of corneal hysteresis.
  
  
  RESULTS
  No intraoperative or postoperative complications were found. Uncorrected distance and near visual acuities (UCDVA and UCNVA) were improved obviously after surgery UCDVA was improved from (4.64 ± 0.25) to (4.89 ± 0.14) (F = 5.919, P < 0.001), and UCNVA was improved from J4.94 to J1.18 (F = 4.926, P < 0.01). The UCNVA in 31 eyes (83.8%) was J1 at 3 months after surgery. Mild overcorrection was the state early after operation, and the refractive power was stable at 1 month after surgery. The average residual spherical equivalent was (-0.63 ± 0.94)D, which was improved significantly from (6.84 ± 2.79)D before surgery. There was no obvious hyperopic regression. The corneal biomechanics did not change before and after surgery.
  
  
  CONCLUSIONS
  Allogeneic corneal lens inlays can be used to correct hyperopic eyes with good safety, effectiveness and predictability. It provides a new choice for hyperopic patients.
authors.affiliation: Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; Email: yh0220@yahoo. com.
authors.forename: Yuehua
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors.forename: Wenbin
authors.initials: W
authors.lastname: Wei
authors.affiliation: Beijing Tongren Eye Center, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors.forename: Ningli
authors.initials: N
authors.lastname: Wang
mesh_terms: D064591:Allografts; D003315:Cornea; D019781:Corneal Topography; D006801:Humans; D006956:Hyperopia / Q000601:surgery*; D007908:Lens, Crystalline / Q000637:transplantation*; D011183:Postoperative Complications; D012029:Refraction, Ocular; D016896:Treatment Outcome; D014787:Vision Tests; D014792:Visual Acuity