title: Assessment of rosmarinic acid content in six Lamiaceae species extracts and their antioxidant and antimicrobial potential.
abstract: In the present study, six indigenous species of Lamiaceae family (Origanum vulgare L., Melissa officinalis L., Rosmarinus officinalis L., Ocimum basilicum L., Salvia officinalis L. and Hyssopus officinalis L.), have been analyzed to assess the rosmarinic acid, phenyl propane derivatives and polyphenolic contents and their antioxidant and antimicrobial potential. HPLC-MS method has been used for the analysis ofrosmarinicacid. The phenyl propane derivatives and total phenolic contents were determined using spectrophotometric method. The ethanolic extracts were screened for antioxidant activities by DPPH radical scavenging, HAPX (hemoglobin ascorbate per oxidase activity inhibition), and EPR (electron paramagnetic resonance) methods. The ethanolic extracts revealed the presence of rosmarinic acid in the largest amount in O. vulgare (12.40mg/g) and in the lowest in R. officinalis (1.33 mg/g). O. vulgare extracts exhibited the highest antioxidant capacity, in line with the rosmarinic acid and polyphenolic contents. The antimicrobial testing showed a significant activity against L. monocytogenes, S. aureus and C. albicans for all six extracts.
authors.affiliation: Iuliu Hatieganu University of Medicine and Pharmacy, Creanga Street, Cluj-Napoca, Romania.
authors.forename: Daniela
authors.initials: D
authors.lastname: Benedec
authors.affiliation: Iuliu Hatieganu University of Medicine and Pharmacy, Creanga Street, Cluj-Napoca, Romania.
authors.forename: Daniela
authors.initials: D
authors.lastname: Hanganu
authors.affiliation: Iuliu Hatieganu University of Medicine and Pharmacy, Creanga Street, Cluj-Napoca, Romania.
authors.forename: Ilioara
authors.initials: I
authors.lastname: Oniga
authors.affiliation: Iuliu Hatieganu University of Medicine and Pharmacy, Creanga Street, Cluj-Napoca, Romania.
authors.forename: Brindusa
authors.initials: B
authors.lastname: Tiperciuc
authors.affiliation: Vasile Goldis Western University of Arad, 86 L. Rebreanu Street and Plantextrakt, Radaia, Cluj, Romania.
authors.forename: Neli-Kinga
authors.initials: NK
authors.lastname: Olah
authors.affiliation: Department of Physics of Nanostructured Materials, National Institute for Research and Development of Isotopic and Molecular Technologies, Donath Street, Cluj-Napoca, Romania.
authors.forename: Oana
authors.initials: O
authors.lastname: Raita
authors.affiliation: Babes-Bolyai University, 11 A. Janos Street, Cluj-Napoca, Romania.
authors.forename: Cristina
authors.initials: C
authors.lastname: Bischin
authors.affiliation: Babes-Bolyai University, 11 A. Janos Street, Cluj-Napoca, Romania.
authors.forename: Radu
authors.initials: R
authors.lastname: Silaghi-Dumitrescu
authors.affiliation: Iuliu Hatieganu University of Medicine and Pharmacy, Creanga Street, Cluj-Napoca, Romania.
authors.forename: Laurian
authors.initials: L
authors.lastname: Vlase