title: A Dual Sensor for pH and Hydrogen Peroxide Using Polymer-Coated Optical Fibre Tips.
abstract: This paper demonstrates the first single optical fibre tip probe for concurrent detection of both hydrogen peroxide (H₂O₂) concentration and pH of a solution. The sensor is constructed by embedding two fluorophores: carboxyperoxyfluor-1 (CPF1) and seminaphtharhodafluor-2 (SNARF2) within a polymer matrix located on the tip of the optical fibre. The functionalised fibre probe reproducibly measures pH, and is able to accurately detect H₂O₂ over a biologically relevant concentration range. This sensor offers potential for non-invasive detection of pH and H₂O₂ in biological environments using a single optical fibre.
authors.affiliation: ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. malcolm.purdey@adelaide.edu.au.|Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. malcolm.purdey@adelaide.edu.au.|Discipline of Chemistry, School of Physical Sciences, The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. malcolm.purdey@adelaide.edu.au.
authors.forename: Malcolm S
authors.initials: MS
authors.lastname: Purdey
authors.affiliation: ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. jeremy.thompson@adelaide.edu.au.|Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. jeremy.thompson@adelaide.edu.au.|Robinson Research Institute, School of Medicine, The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. jeremy.thompson@adelaide.edu.au.
authors.forename: Jeremy G
authors.initials: JG
authors.lastname: Thompson
authors.affiliation: ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. tanya.monro@unisa.edu.au.|Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. tanya.monro@unisa.edu.au.|University of South Australia, North Terrace, Adelaide 5001, SA, Australia. tanya.monro@unisa.edu.au.
authors.forename: Tanya M
authors.initials: TM
authors.lastname: Monro
authors.affiliation: ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. andrew.abell@adelaide.edu.au.|Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. andrew.abell@adelaide.edu.au.|Discipline of Chemistry, School of Physical Sciences, The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. andrew.abell@adelaide.edu.au.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Abell
authors.affiliation: ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. erik.schartner@adelaide.edu.au.|Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. erik.schartner@adelaide.edu.au.
authors.forename: Erik P
authors.initials: EP
authors.lastname: Schartner
mesh_terms: D005336:Fiber Optic Technology / Q000379:methods*; D005456:Fluorescent Dyes / Q000032:analysis / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D055100:Optical Fibers; D011108:Polymers / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D011108:Polymers; D006861:Hydrogen Peroxide
keywords: dual sensor; fibre tip sensor; hydrogen peroxide probe; optical fibre; pH sensor