title: The presence of cardiophrenic angle lymph nodes is not an indicator of peritoneal carcinomatosis from colorectal cancer on MDCT: Results of a case-control study.
abstract: OBJECTIVE
  To determine if the presence of cardiophrenic angle lymph nodes (CPALNs) on multidetector-row computed tomography (MDCT) can be considered as an indicator of peritoneal carcinomatosis (PC) in patients with colorectal cancer (CRC).
  
  
  METHODS
  Two groups of 101 patients each were retrospectively included. Group 1 included patients with PC from CRC and Group 2 included patients with CRC without PC. MDCT examinations were analyzed by two readers working in consensus for the presence or absence of CPALNs and, when present for their dimensions (short and long axis), location (right, left or bilateral) and shape (oval or rounded).
  
  
  RESULTS
  Prevalence of CPALNs was 29% in Group 1 and 32% in Group 2. No differences in prevalence of CPALNs were found between the two groups (P = 0.458). Presence of CPALNs had a sensitivity of 29% (95%CI: 23-35%) for the diagnosis of PC and a specificity of 68% (95%CI = 62-74%). No differences in CPALN dimensions, location and shape were found between these two groups.
  
  
  CONCLUSIONS
  Presence of CPALNs cannot be considered as an indicator of PC in patients with CRC. In addition, when present, CPALNs have similar dimensions, location and shapes in patients with PC from CRC than in those without PC.
authors.affiliation: Department of Body and Interventional Imaging, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France. Electronic address: maxime.barat89@gmail.com.
authors.forename: M
authors.initials: M
authors.lastname: Barat
authors.affiliation: Department of Body and Interventional Imaging, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France; Université Paris-Diderot, Sorbonne-Paris Cité, 10 rue de Verdun, 75010 Paris, France; UMR INSERM 965, Hôpital Lariboisière, 2 rue Amboise Paré, 75010 Paris, France. Electronic address: philippe.soyer@lrb.aphp.fr.
authors.forename: P
authors.initials: P
authors.lastname: Soyer
authors.affiliation: Université Paris-Diderot, Sorbonne-Paris Cité, 10 rue de Verdun, 75010 Paris, France; UMR INSERM 965, Hôpital Lariboisière, 2 rue Amboise Paré, 75010 Paris, France; Department of Digestive Surgery, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France. Electronic address: Clarisse.eveno@lrb.aphp.fr.
authors.forename: C
authors.initials: C
authors.lastname: Eveno
authors.affiliation: Department of Body and Interventional Imaging, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France. Electronic address: raphael.dautry@aphp.fr.
authors.forename: R
authors.initials: R
authors.lastname: Dautry
authors.affiliation: Department of Body and Interventional Imaging, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France. Electronic address: laetitia.perronne@gmail.com.
authors.forename: L
authors.initials: L
authors.lastname: Perronne
authors.affiliation: Department of Body and Interventional Imaging, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France. Electronic address: youcef.guerrache@lrb.aphp.fr.
authors.forename: Y
authors.initials: Y
authors.lastname: Guerrache
authors.affiliation: Department of Body and Interventional Imaging, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France. Electronic address: mourad.boudiaf@lrb.aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Boudiaf
authors.affiliation: Université Paris-Diderot, Sorbonne-Paris Cité, 10 rue de Verdun, 75010 Paris, France; UMR INSERM 965, Hôpital Lariboisière, 2 rue Amboise Paré, 75010 Paris, France; Department of Digestive Surgery, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France. Electronic address: Marc.pocard@lrb.php.fr.
authors.forename: M
authors.initials: M
authors.lastname: Pocard
authors.affiliation: Department of Body and Interventional Imaging, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France; Université Paris-Diderot, Sorbonne-Paris Cité, 10 rue de Verdun, 75010 Paris, France; UMR INSERM 965, Hôpital Lariboisière, 2 rue Amboise Paré, 75010 Paris, France. Electronic address: anthony.dohan@aphp.fr.
authors.forename: A
authors.initials: A
authors.lastname: Dohan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000175:diagnosis* / Q000556:secondary; D016022:Case-Control Studies; D015179:Colorectal Neoplasms / Q000473:pathology*; D003964:Diaphragm; D005260:Female; D006321:Heart; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D010534:Peritoneal Neoplasms / Q000175:diagnosis* / Q000556:secondary; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
keywords: Cardiophrenic angle lymph nodes; Colorectal cancer; Computed tomography; Peritoneal carcinomatosis