title: Genetic characterization of highly pathogenic H5 influenza viruses from poultry in Taiwan, 2015.
abstract: Phylogenetic analysis of the highly pathogenic avian influenza (HPAI) H5 viruses causing recent outbreaks in Taiwan showed that they belonged to the Asian HPAI H5 lineage, clade 2.3.4.4 viruses, and were apparently introduced by migratory birds. These viruses reassorted with Eurasian influenza gene pool viruses and formed five genotypic variants. As Taiwan has a similar influenza ecosystem to southern China, the HPAI H5 lineage could become established and enzootic in the island.
authors.affiliation: Joint Influenza Research Centre, Shantou University Medical College, Shantou, Guangdong, China; Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region.
authors.forename: Pei-Yu
authors.initials: PY
authors.lastname: Huang
authors.affiliation: Genomics Research Center, Academia Sinica, Taipei, Taiwan.
authors.forename: Chang-Chun David
authors.initials: CD
authors.lastname: Lee
authors.affiliation: Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region; State Key Laboratory of Emerging Infectious Diseases (Shenzhen Base), Shenzhen Third People's Hospital, Shenzhen, China.
authors.forename: Chun-Hung
authors.initials: CH
authors.lastname: Yip
authors.affiliation: Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region.
authors.forename: Chung-Lam
authors.initials: CL
authors.lastname: Cheung
authors.affiliation: Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region.
authors.forename: Guangchuang
authors.initials: G
authors.lastname: Yu
authors.affiliation: Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region.
authors.forename: Tommy Tsan-Yuk
authors.initials: TT
authors.lastname: Lam
authors.affiliation: Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region.
authors.forename: David K
authors.initials: DK
authors.lastname: Smith
authors.affiliation: Joint Influenza Research Centre, Shantou University Medical College, Shantou, Guangdong, China; Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region; State Key Laboratory of Emerging Infectious Diseases (Shenzhen Base), Shenzhen Third People's Hospital, Shenzhen, China. Electronic address: zhuhch@hku.hk.
authors.forename: Huachen
authors.initials: H
authors.lastname: Zhu
authors.affiliation: Joint Influenza Research Centre, Shantou University Medical College, Shantou, Guangdong, China; Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region; State Key Laboratory of Emerging Infectious Diseases (Shenzhen Base), Shenzhen Third People's Hospital, Shenzhen, China. Electronic address: yguan@hku.hk.
authors.forename: Yi
authors.initials: Y
authors.lastname: Guan
mesh_terms: D000818:Animals; D005814:Genes, Viral; D005838:Genotype; D062306:Geography, Medical; D009980:Influenza A virus / Q000145:classification* / Q000235:genetics*; D005585:Influenza in Birds / Q000453:epidemiology / Q000821:virology*; D010802:Phylogeny; D058974:Phylogeography; D011200:Poultry; D013624:Taiwan / Q000453:epidemiology
keywords: Clade 2.3.4.4; Eurasian gene pool; Genotype; H5N8; Migratory bird; Reassortment