title: Preferences of lung cancer patients for treatment and decision-making: a systematic literature review.
abstract: The consideration of patient preferences in decision-making has become more important, especially for life-threatening diseases such as lung cancer. This paper aims to identify the preferences of lung cancer patients with regard to their treatment and involvement in the decision-making process. We conducted a systematic literature review from 12 electronic databases and included studies published between 2000 and 2012. A total of 20 studies were included in this review. These revealed that lung cancer patients do have preferences that should be considered in treatment decisions; however, these preferences are not homogenous. We found that patients often consider life extension to be more important than the health-related quality of life or undesirable side effects. This preference seems to depend on patient age. Nausea and vomiting are the most important side effects to be avoided; the relevance of other side effects differs highly between subgroups. The majority of lung cancer patients, nevertheless, seem to prefer a passive rather than an active role in decision-making, although the self-reported preferences differed partly from the physicians' perceptions. Overall, we identified an urgent need for larger studies that are suitable for subgroup analyses and incorporate multi-attributive measurement techniques.
authors.affiliation: Leibniz University Hannover, Center for Health Economics Research Hannover (CHERH), Hannover, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Schmidt
authors.affiliation: Leibniz University Hannover, Center for Health Economics Research Hannover (CHERH), Hannover, Germany.|Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Damm
authors.affiliation: Leibniz University Hannover, Center for Health Economics Research Hannover (CHERH), Hannover, Germany.|Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Prenzler
authors.affiliation: Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.|Hannover Medical School, Clinic for Pneumology, Hannover, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Golpon
authors.affiliation: Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.|Hannover Medical School, Clinic for Pneumology, Hannover, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Welte
mesh_terms: D003657:Decision Making; D006801:Humans; D008020:Life Support Care / Q000523:psychology; D008175:Lung Neoplasms / Q000523:psychology* / Q000628:therapy; D010358:Patient Participation / Q000523:psychology*; D057240:Patient Preference; D011788:Quality of Life
keywords: decision-making; lung cancer; patient; preference; systematic review; treatment