title: Histopathological case report of high grade salivary duct carcinoma.
abstract: The case of a 39-year-old man with slowly growing mass in the superior part of left parotid region is described. Patient presented neurological symptoms including hypomobility of lower left eyelid and inability of complete closure of left side eyelids resulting in conjunctivitis and hyperlacrimation. Routine physical examination supported by image and laboratory tests was performed. Pathomorphological results of hematoxylin and eosin staining as well immunohistochemical examination in view of clinical presentation pointed to diagnosis of high grade salivary duct carcinoma. Rare incidence, histological view similar to breast cancer and body localization are sufficient reasons for further analyses and descriptions of this type of lesions.
authors.forename: Jiri
authors.initials: J
authors.lastname: Borovec
authors.forename: Martin
authors.initials: M
authors.lastname: Cegan
authors.forename: Katerina
authors.initials: K
authors.lastname: Mala
authors.forename: Natalia
authors.initials: N
authors.lastname: Harmash
authors.forename: Petr
authors.initials: P
authors.lastname: Chramosta
authors.forename: Christopher
authors.initials: C
authors.lastname: Kobierzycki
authors.affiliation: Department of Laboratory Genetics University Hospital Kralovske Vinohrady, Prague. vbobek@centrum.cz.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Bobek
mesh_terms: D000328:Adult; D044584:Carcinoma, Ductal / Q000473:pathology*; D003231:Conjunctivitis; D006416:Hematoxylin; D006801:Humans; D065906:Hyperlactatemia; D007150:Immunohistochemistry; D008297:Male; D018987:Salivary Ducts / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000473:pathology*
chemical_list: D006416:Hematoxylin
keywords: parotid malignancy; salivary duct carcinoma; salivary gland