title: Comparing three methods of computerised cognitive training for older adults with subclinical cognitive decline.
abstract: Cognitive rehabilitation for mild cognitive impairment (MCI) and early Alzheimer's disease is readily available to the geriatric population. Initial evidence suggests that techniques incorporating motivational strategies to enhance treatment engagement may provide more benefit than computerised training alone. Seventy four adults with subclinical cognitive decline were randomly assigned to computerised cognitive training (CCT), Cognitive Vitality Training (CVT), or an Active Control Group (ACG), and underwent neuropsychological evaluations at baseline and four-month follow-up. Significant differences were found in changes in performance on the Modified Mini Mental State Examination (mMMSE) and measures of verbal learning and memory across treatment groups. Experimental groups showed greater preservation of functioning on the mMMSE than the ACG group, the CVT group performed better than the ACG group on one measure of verbal learning and both measures of verbal memory, and the CCT group performed better than the ACG group on one measure of verbal learning and one measure of verbal memory. There were no significant group differences between the CVT and CCT groups on measures of verbal learning or memory. It was concluded that computerised cognitive training may offer the most benefit when incorporated into a therapeutic milieu rather than administered alone, although both appear superior to more generic forms of cognitive stimulation.
authors.affiliation: a Department of Neurology , Columbia University Medical Center , New York , NY , USA.
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Gooding
authors.affiliation: b Olin Neuropsychiatry Research Center , Hartford Hospital/The Institute of Living , Hartford , CT , USA.
authors.forename: Jimmy
authors.initials: J
authors.lastname: Choi
authors.affiliation: c Department of Psychiatry , Yale University School of Medicine , New Haven , CT , USA.|d VA Connecticut Healthcare System , West Haven , CT , USA.
authors.forename: Joanna M
authors.initials: JM
authors.lastname: Fiszdon
authors.affiliation: c Department of Psychiatry , Yale University School of Medicine , New Haven , CT , USA.|d VA Connecticut Healthcare System , West Haven , CT , USA.
authors.forename: Kirsten
authors.initials: K
authors.lastname: Wilkins
authors.affiliation: c Department of Psychiatry , Yale University School of Medicine , New Haven , CT , USA.|d VA Connecticut Healthcare System , West Haven , CT , USA.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Kirwin
authors.affiliation: c Department of Psychiatry , Yale University School of Medicine , New Haven , CT , USA.|e Department of Psychiatry , Yale Alzheimer's Disease Research Unit , New Haven , CT , USA.
authors.forename: Christopher H
authors.initials: CH
authors.lastname: van Dyck
authors.affiliation: f Columbia Psychiatry , New York State Psychiatric Institute at Columbia University Medical Center , New York , NY , USA.
authors.forename: Davangere
authors.initials: D
authors.lastname: Devanand
authors.affiliation: c Department of Psychiatry , Yale University School of Medicine , New Haven , CT , USA.|d VA Connecticut Healthcare System , West Haven , CT , USA.
authors.forename: Morris D
authors.initials: MD
authors.lastname: Bell
authors.affiliation: g Department of Psychology , Fordham University , Bronx , NY , USA.|h Departments of Pathology & Psychiatry , Mount Sinai School of Medicine , New York , NY , USA.
authors.forename: Monica
authors.initials: M
authors.lastname: Rivera Mindt
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D060825:Cognitive Dysfunction / Q000534:rehabilitation*; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D000066530:Neurological Rehabilitation / Q000379:methods*; D009483:Neuropsychological Tests; D013813:Therapy, Computer-Assisted / Q000379:methods*; D014706:Verbal Learning
keywords: Alzheimer's disease; Cognitive rehabilitation; Computerised cognitive training; Mild cognitive impairment