title: Association between leukocyte count and sarcopenia in postmenopausal women: The Korean National Health and Nutrition Examination Survey.
abstract: OBJECTIVE
  To investigate the association between leukocyte counts and sarcopenia according in postmenopausal women.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  We examined the relationship between leukocyte counts and sarcopenia in 2152 post-menopausal Korean women who participated in the 2010-2011 Korean National Health Examination and Nutrition Survey. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by weight (%) that was greater than 1SD below the mean of young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across leukocyte count quartiles (Q1:≤4710, Q2:4720-5600, Q3:5610-6600, and Q4:≥6610cells/μL) after adjusting for confounding variables.
  
  
  RESULTS
  The prevalence of sarcopenia gradually increased in accordance with leukocyte quartiles. Compared with the lowest quartile of leukocyte counts, the corresponding OR (95% CI) of the highest quartile of leukocyte counts for sarcopenia was 2.41 (1.12-5.22) after adjusting for age, waist circumference, cigarette smoking, alcohol intake, regular exercise, blood pressure, fasting plasma glucose, triglyceride, and HDL-cholesterol.
  
  
  CONCLUSIONS
  Leukocyte counts were positively related to a higher risk of sarcopenia in postmenopausal women.
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Medicine, Graduate School, Yonsei University, Seoul, Republic of Korea.
authors.forename: Tae-Ha
authors.initials: TH
authors.lastname: Chung
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Medicine, Graduate School, Yonsei University, Seoul, Republic of Korea.
authors.forename: Jae-Yong
authors.initials: JY
authors.lastname: Shim
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Medicine, Graduate School, Yonsei University, Seoul, Republic of Korea. Electronic address: ukyjhome@yuhs.ac.
authors.forename: Yong-Jae
authors.initials: YJ
authors.lastname: Lee
mesh_terms: D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008875:Middle Aged; D009749:Nutrition Surveys; D017698:Postmenopause; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D055948:Sarcopenia / Q000097:blood* / Q000453:epidemiology*
keywords: Inflammation; Leukocyte count; Postmenopausal women; Sarcopenia