title: Abrupt Development of Plasma Cell Leukemia in a Patient with Chronic Anemia under Follow-up.
abstract: Plasma cell leukemia (PCL) is a very rare and progressive hematologic malignancy with unpleasant prognosis, which present with monoclonal proliferation of plasma cells in peripheral blood. Here we report a 52-year-old female case of PCL which diagnosed by morphology and immunohistochemistery (IHC) study. IHC revealed CD20+/CD38+/CD138+/CD56-/kappa-/lambda+. We diagnose PCL on peripheral blood. IHC can be helpful for prognostic determination.
authors.affiliation: Pathology Department, Bushehr University of Medical Sciences, Bushehr, Iran. mrfarzaneh@yahoo.com.
authors.forename: Mohamad Reza
authors.initials: MR
authors.lastname: Farzaneh
authors.affiliation: Pathology Department, Bushehr University of Medical Sciences, Bushehr, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Moradi
authors.affiliation: Department of Oncology and Hematology, Bushehr University of Medical Sciences, Bushehr, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Ravanbod
authors.affiliation: Boushehr University of Medical Siences, Boushehr, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Daghbashi
mesh_terms: D000740:Anemia / Q000175:diagnosis* / Q000188:drug therapy; D000971:Antineoplastic Combined Chemotherapy Protocols; D019002:CD56 Antigen / Q000097:blood*; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology*
chemical_list: D019002:CD56 Antigen