title: Pachygyria Presented as Mania.
abstract: Psychiatric manifestation of pachygyria, a neuronal migration disorder is rare in literature; rarer if it is bipolar disorder specifically. Here, we report a case of mania and seizure who subsequently diagnosed as pachygyria. Proper literature about pathophysiology is discussed and recently discovered putative genetic role in bipolar disorder explained. This case also emphasis the importance of detailed history taking and imaging investigation even in a pure psychiatric presentation.
authors.affiliation: Depratment of Psychiatry, Medical College, Kolkata, India.
authors.forename: Seshadri Sekhar
authors.initials: SS
authors.lastname: Chatterjee
authors.affiliation: Depratment of Psychiatry, Medical College, Kolkata, India.
authors.forename: Devlina
authors.initials: D
authors.lastname: Talapatra
authors.affiliation: Depratment of Psychiatry, Medical College, Kolkata, India.
authors.forename: Rudra
authors.initials: R
authors.lastname: Acharya
authors.affiliation: Institute of Psychiatry, IPGMER, Kolkata, West Bengal, India.
authors.forename: Sujit
authors.initials: S
authors.lastname: Sarkhel
keywords: Bipolar disorder; magnetic resonance imaging; pachygyria