title: Evidence for partial pharmaceutical reversal of the cancer anorexia-cachexia syndrome: the case of anamorelin.
abstract: A major component of the cancer anorexia-cachexia syndrome is a decline in food intake. Up until now none of the drugs that improve appetite also improve skeletal muscle. Recent studies have suggested that the oral ghrelin-analog, anamorelin, increased food intake and muscle mass. Unfortunately, it does not increase muscle power. Its regulatory future is uncertain, although it has important clinical effects.
authors.affiliation: Division of Innovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Center Göttingen (UMG) Göttingen, Germany.
authors.forename: Stefan D
authors.initials: SD
authors.lastname: Anker
authors.affiliation: Monash University Melbourne, Australia ; University of Warwick Coventry, UK.
authors.forename: Andrew J S
authors.initials: AJ
authors.lastname: Coats
authors.affiliation: Divisions of Geriatric Medicine and Endocrinology, Saint Louis University School of Medicine St Louis, MO, USA.
authors.forename: John E
authors.initials: JE
authors.lastname: Morley