title: Methods for the determination of biomarkers of exposure to emerging pollutants in human specimens.
abstract: Biomonitoring is a very useful tool for assessing human exposure to environmental pollutants. This review discusses recent methods for the quantitative measurement of biomarkers of exposure to different classes of chemicals used in personal-care products (e.g., musk fragrances, preservatives, UV filters, and insect repellents) and consumer products (e.g., organophosphate flame retardants, phthalate esters, perfluorinated compounds, and industrial phenols). The measurements are mainly taken in urine, blood, and breast milk. We also discuss the different procedures commonly used for sample-pretreatment, extraction, and clean up, and chromatographic techniques currently used to determine these compounds. Finally, we present data on the main biomarkers occurring in different human specimens.
authors.affiliation: Public Health Research Center of Valencia (CSISP), Av. Catalunya, 21, 46020, Valencia, Spain.
authors.forename: Vicent
authors.initials: V
authors.lastname: Yusa
authors.affiliation: Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Ye
authors.affiliation: Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Antonia M
authors.initials: AM
authors.lastname: Calafat
keywords: Biomarker; Blood; Breast milk; Emerging pollutant; Flame retardant; Liquid chromatography with tandem mass spectrometry (LC-MS/MS); Musk fragrance; Perfluorinated compound; Personal-care product; Urine