title: Physiological parameters as a tool in the diagnosis of fibromyalgia syndrome in females: A preliminary study.
abstract: OBJECTIVE
  Although fibromyalgia (FM) syndrome is associated with many symptoms, there is as yet no specific finding or laboratory test diagnostic of this syndrome. The physical examination and laboratory tests may be helpful in figuring out this syndrome.
  
  
  METHODS
  The heart rate, respiration rate, body temperature (TEMP), height, body weight, hemoglobin level, erythrocyte sedimentation rate, white blood cell count, platelet count (PLT), rheumatoid factor and C-reactive protein levels and electrocardiograms (ECG) of FM patients were compared with those of control individuals. In addition, the predictive value of these tests was evaluated via receiver operating characteristic (ROC) analysis.
  
  
  RESULTS
  The results showed that the TEMP and the PLT were higher in the FM group compared with the control group. Also, ST heights in ECGs which corresponds to a period of ventricle systolic depolarization, showed evidence of a difference between the FM and the control groups. There was no difference observed in terms of the other parameters. According to the ROC analysis, PLT, TEMP and ST height have predictive capacities in FM.
  
  
  CONCLUSIONS
  Changes in hormonal factors, peripheral blood circulation, autonomous system activity disorders, inflammatory incidents, etc., may explain the increased TEMP in the FM patients. The high PLT level may signify a thromboproliferation or a possible compensation caused by a PLT functional disorder. ST depression in FM patients may interrelate with coronary pathology. Elucidating the pathophysiology underlying the increases in TEMP and PLT and the decreases in ST height may help to explain the etiology of FM.
authors.affiliation: Mugla Sitki Kocman University, Faculty of Medicine, Department of Physiology, Mugla 48000, Turkey. Electronic address: onurelmas@outlook.com.
authors.forename: Onur
authors.initials: O
authors.lastname: Elmas
authors.affiliation: Suleyman Demirel University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Isparta, Turkey.
authors.forename: Sedat
authors.initials: S
authors.lastname: Yildiz
authors.affiliation: Akdeniz University, Faculty of Engineering, Department of Electrical and Electronics Engineering, Antalya, Turkey.
authors.forename: Suleyman
authors.initials: S
authors.lastname: Bilgin
authors.affiliation: Suleyman Demirel University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Isparta, Turkey.
authors.forename: Seden
authors.initials: S
authors.lastname: Demirci
authors.affiliation: Suleyman Demirel University, Department of Electronics and Communication Engineering, Isparta, Turkey.
authors.forename: Selcuk
authors.initials: S
authors.lastname: Comlekci
authors.affiliation: Suleyman Demirel University, Faculty of Medicine, Department of Neurology, Isparta, Turkey.
authors.forename: Hasan Rifat
authors.initials: HR
authors.lastname: Koyuncuoglu
authors.affiliation: Yildirim Beyazit University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Ankara, Turkey.
authors.forename: Selami
authors.initials: S
authors.lastname: Akkus
authors.affiliation: Akdeniz University, Faculty of Engineering, Department of Electrical and Electronics Engineering, Antalya, Turkey.
authors.forename: Omer Halil
authors.initials: OH
authors.lastname: Colak
authors.affiliation: Sakarya University, Faculty of Engineering, Department of Electrical and Electronics Engineering, Sakarya, Turkey.
authors.lastname: Etem Koklukaya
authors.affiliation: Sakarya University, Faculty of Engineering, Department of Electrical and Electronics Engineering, Sakarya, Turkey.
authors.forename: Evren
authors.initials: E
authors.lastname: Arslan
authors.affiliation: Sakarya University, Faculty of Engineering, Department of Electrical and Electronics Engineering, Sakarya, Turkey.
authors.forename: Ozhan
authors.initials: O
authors.lastname: Ozkan
authors.affiliation: Mehmet Akif Ersoy University, Burdur Junior Technical College, Burdur, Turkey.
authors.forename: Gurkan
authors.initials: G
authors.lastname: Bilgin
mesh_terms: D000328:Adult; D001799:Blood Sedimentation; D001831:Body Temperature; D002097:C-Reactive Protein / Q000032:analysis; D005260:Female; D005356:Fibromyalgia / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology*; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D010976:Platelet Count; D012217:Rheumatoid Factor / Q000097:blood; D055815:Young Adult
chemical_list: D002097:C-Reactive Protein; D012217:Rheumatoid Factor
keywords: Body temperature; Electrocardiogram; Fibromyalgia; Physiological parameters; Platelet level