title: Mitochondrial DNA study in domestic chicken.
abstract: Mitochondrial DNA has the characteristic of quick evolution, matrilineal inheritance, and simple molecular structure, and it serves as the most used marker for molecular study. As an important role of genomics, studying it can help understand the origins, history, and adaptation of domestication. Because of its wide spread popularity, chicken is one of the important domestic animals, which provides humans with a stable source of protein, including both meat and eggs. This article reviews recent studies of chicken mitochondrial DNA. Mitochondrial D-loop and mitochondrial genomics pinpoint the geographic origins of the domestic chicken which was multiple origins; moreover, the mitochondria gene mutation has an association with high-altitude adaptation and the mitochondria-associated diseases' study in poultry is not performed.
authors.affiliation: a Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University , Ya'an, Sichuan , China.
authors.forename: Dan
authors.initials: D
authors.lastname: Lan
authors.affiliation: a Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University , Ya'an, Sichuan , China.
authors.forename: Yaodong
authors.initials: Y
authors.lastname: Hu
authors.affiliation: a Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University , Ya'an, Sichuan , China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhu
authors.affiliation: a Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University , Ya'an, Sichuan , China.
authors.forename: Yiping
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000235:genetics; D030161:Avian Proteins / Q000235:genetics; D002645:Chickens / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics* / Q000378:metabolism; D011401:Promoter Regions, Genetic
chemical_list: D030161:Avian Proteins; D004272:DNA, Mitochondrial
keywords: Chicken; disease; high-altitude adaptation; mitochondrial DNA; multiple origins