title: Children with dermatological conditions admitted to paediatric intensive care: analysis of a national clinical audit database.
abstract: There is little published literature about dermatological conditions in paediatric intensive care units (PICUs). The aim of this study was to describe the range of skin disorders in children admitted to PICUs in the UK and Ireland using data from a national audit. An analysis was conducted using data for 2002 - 2010 from the Paediatric Intensive Care Audit Network (PICANet). In total, 999 admissions of 882 children were identified, representing 0.8% of all PICU admissions. The most frequent dermatological conditions were skin infections, including cellulitis and necrotizing fasciitis, and inflammatory conditions. In 28% of cases, the dermatological diagnosis was considered the reason for PICU admission, in 35% it was a manifestation of systemic disease and in 37% it was considered incidental. Overall mortality was similar to the general PICU population, with 52 deaths (5.2%), but was greater in children with vascular/haematological conditions.
authors.affiliation: Department of Dermatology, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.
authors.forename: S M C
authors.initials: SM
authors.lastname: George
authors.affiliation: Department of Paediatrics, Stoke Mandeville Hospital, Buckinghamshire, UK.
authors.forename: S M
authors.initials: SM
authors.lastname: Sen
authors.affiliation: Intensive Care National Audit and Research Centre (ICNARC), London, UK.
authors.forename: D A
authors.initials: DA
authors.lastname: Harrison
authors.affiliation: Paediatric Intensive Care Audit Network (PICANet), University of Leeds, Leeds, UK.
authors.forename: P
authors.initials: P
authors.lastname: McShane
authors.affiliation: Department of Paediatrics, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.
authors.forename: K
authors.initials: K
authors.lastname: Patel
authors.affiliation: Department of Dermatology, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.
authors.forename: C R
authors.initials: CR
authors.lastname: Darley
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003422:Critical Care / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015278:Intensive Care Units, Pediatric / Q000706:statistics & numerical data*; D007494:Ireland / Q000453:epidemiology; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D010343:Patient Admission / Q000706:statistics & numerical data; D012871:Skin Diseases / Q000145:classification* / Q000453:epidemiology* / Q000401:mortality*; D006113:United Kingdom / Q000453:epidemiology