title: [Clinicopathologic features of inflammatory fibroid polyp in gastrointestinal tract].
abstract: OBJECTIVE
  To study the clinicopathologic characteristics, immunophenotypes, pathologic diagnosis and differential diagnosis of gastrointestinal inflammatory fibroid polyp (IFP).
  
  
  METHODS
  The clinical data, histologic features and immunohistochemical results of 6 cases of gastrointestinal inflammatory fibroid polyp were analyzed, with review of literature.
  
  
  RESULTS
  There were altogether 5 women and a man. The age of patients ranged from 44 to 87 years (median age = 61 years and mean age = 62 years). The sites of involvement included stomach (number = 2), jejunum (number = 2), distal ileum (number = 1) and rectum (number = 1). The patients often presented with abdominal pain or discomfort and tarry stool. All the cases studied showed similar morphology, were submucosa-based and composed of bland spindle cells associated with loose collagenous stroma and perivascular edema. Prominent concentric fibroblastic proliferation ("onion-skin" appearance) and eosinophilic infiltrate were characteristics. Three of the patients underwent surgical resection. The remaining patients had the lesions removed with endoscopy. Follow-up data were available in 5 patients and none of them had disease recurrence or metastasis.
  
  
  CONCLUSIONS
  IFP is a rare benign tumor of gastrointestinal tract. Correct diagnosis primarily relies on pathologic examination. It needs to be distinguished from gastrointestinal stromal tumors or inflammatory myofibroblastic tumor.
authors.affiliation: Department of Pathology, Shaoxing People's Hospital, Shaoxing 312000, China.
authors.forename: Jianguo
authors.initials: J
authors.lastname: Wei
authors.affiliation: Affiated Hospital of Academy of Military Medical Sciences, Beijing 100071, China; E-mail: xuchunweibbb@163.com.
authors.forename: Chunwei
authors.initials: C
authors.lastname: Xu
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Aijing
authors.initials: A
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D041981:Gastrointestinal Tract / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007249:Inflammation / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011127:Polyps / Q000473:pathology*