title: IgG4-related sialadenitis: IgG4 is helpful, but biopsies are still crucial.
abstract: IgG4-related disease is rare, but a frequent differential diagnosis for malignant and for autoimmune diseases. Li and colleagues report the largest cohort of patients with IgG4-related sialadenitis. The observations reveal that the most important diagnostic step is obtaining biopsies. In addition, the IgG4 serum concentration may be a biomarker for the disease progression.
authors.affiliation: Klinik für Immunologie und Rheumatologie, Carl-Neuberg-Straße 1, 30625, Hannover, Germany. witte.torsten@mh-hannover.de.
authors.forename: Torsten
authors.initials: T
authors.lastname: Witte
authors.affiliation: Sektion Rheumatologie und Klinische Immunologie, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Pettenkoferstraße 8a, 80336, München, Germany.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Schulze-Koops
mesh_terms: D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D012793:Sialadenitis / Q000097:blood* / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D007074:Immunoglobulin G