title: Modulating Memory Performance in Healthy Subjects with Transcranial Direct Current Stimulation Over the Right Dorsolateral Prefrontal Cortex.
abstract: OBJECTIVE
  The role of the Dorsolateral Prefrontal Cortex (DLPFC) in recognition memory has been well documented in lesion, neuroimaging and repetitive Transcranial Magnetic Stimulation (rTMS) studies. The aim of the present study was to investigate the effects of transcranial Direct Current Stimulation (tDCS) over the left and the right DLPFC during the delay interval of a non-verbal recognition memory task.
  
  
  METHODS
  36 right-handed young healthy subjects participated in the study. The experimental task was an Italian version of Recognition Memory Test for unknown faces. Study included two experiments: in a first experiment, each subject underwent one session of sham tDCS and one session of left or right cathodal tDCS; in a second experiment each subject underwent one session of sham tDCS and one session of left or right anodal tDCS.
  
  
  RESULTS
  Cathodal tDCS over the right DLPFC significantly improved non verbal recognition memory performance, while cathodal tDCS over the left DLPFC had no effect. Anodal tDCS of both the left and right DLPFC did not modify non verbal recognition memory performance.
  
  
  CONCLUSIONS
  Complementing the majority of previous studies, reporting long term memory facilitations following left prefrontal anodal tDCS, the present findings show that cathodal tDCS of the right DLPFC can also improve recognition memory in healthy subjects.
authors.affiliation: Dipartimento di Scienze Psicologiche, Pedagogiche e della Formazione, Università degli Studi di Palermo, Palermo, Italy.|NeuroTeam Life and Science, Palermo, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Smirni
authors.affiliation: Dipartimento di Scienze Psicologiche, Pedagogiche e della Formazione, Università degli Studi di Palermo, Palermo, Italy.|NeuroTeam Life and Science, Palermo, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Turriziani
authors.affiliation: Dipartimento di Scienze Psicologiche, Pedagogiche e della Formazione, Università degli Studi di Palermo, Palermo, Italy.|NeuroTeam Life and Science, Palermo, Italy.
authors.forename: Giuseppa Renata
authors.initials: GR
authors.lastname: Mangano
authors.affiliation: Dipartimento di Scienze Psicologiche, Pedagogiche e della Formazione, Università degli Studi di Palermo, Palermo, Italy.|NeuroTeam Life and Science, Palermo, Italy.|Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.
authors.forename: Lisa
authors.initials: L
authors.lastname: Cipolotti
authors.affiliation: Dipartimento di Scienze Psicologiche, Pedagogiche e della Formazione, Università degli Studi di Palermo, Palermo, Italy.|NeuroTeam Life and Science, Palermo, Italy.|IRCCS Fondazione "SantaLucia", Roma, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Oliveri
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology; D017397:Prefrontal Cortex / Q000502:physiology*; D011930:Reaction Time; D021641:Recognition, Psychology / Q000502:physiology; D065908:Transcranial Direct Current Stimulation / Q000379:methods*; D055815:Young Adult