title: Evaluation of Central Corneal Thickness Using Corneal Dynamic Scheimpflug Analyzer Corvis ST and Comparison with Pentacam Rotating Scheimpflug System and Ultrasound Pachymetry in Normal Eyes.
abstract: Purpose. To assess the repeatability and reproducibility of central corneal thickness (CCT) measurements by corneal dynamic Scheimpflug analyzer Corvis ST in normal eyes and compare the agreement with Pentacam rotating Scheimpflug System and ultrasound pachymetry. Methods. 84 right eyes underwent Corvis ST measurements performed by two operators. The test-retest repeatability (TRT), within-subject coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were used to evaluate the intraoperator repeatability and interoperator reproducibility. CCT measurements also were obtained from Pentacam and ultrasound pachymetry by the first operator. The agreement between the three devices was evaluated with 95% limits of agreement (LoA) and Bland-Altman plots. Results. Corvis ST showed high repeatability as indicated by TRT ≤ 13.0 μm, CoV < 0.9%, and ICC > 0.97. The interoperator reproducibility was also excellent. The CoV was <0.9%, and ICC was >0.97. Corvis ST showed significantly lower values than Pentacam and ultrasound pachymetry (P < 0.001). The 95% LoA between Corvis ST and Pentacam or ultrasound pachymetry were -15.8 to 9.5 μm and -27.9 to 12.3 μm, respectively. Conclusions. Corvis ST showed excellent repeatability and interoperator reproducibility of CCT measurements in normal eyes. Corvis ST is interchangeable with Pentacam but not with ultrasound pachymetry.
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang 325027, China ; Key Laboratory of Vision Science, Ministry of Health of the People's Republic of China, Wenzhou, Zhejiang, China.
authors.forename: Ayong
authors.initials: A
authors.lastname: Yu
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang 325027, China ; Key Laboratory of Vision Science, Ministry of Health of the People's Republic of China, Wenzhou, Zhejiang, China.
authors.forename: Weiqi
authors.initials: W
authors.lastname: Zhao
authors.affiliation: G. B. Bietti Foundation IRCCS, Rome, Italy.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Savini
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang 325027, China.
authors.forename: Zixu
authors.initials: Z
authors.lastname: Huang
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang 325027, China ; Key Laboratory of Vision Science, Ministry of Health of the People's Republic of China, Wenzhou, Zhejiang, China.
authors.forename: Fangjun
authors.initials: F
authors.lastname: Bao
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang 325027, China ; Key Laboratory of Vision Science, Ministry of Health of the People's Republic of China, Wenzhou, Zhejiang, China.
authors.forename: Weicong
authors.initials: W
authors.lastname: Lu
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang 325027, China ; Key Laboratory of Vision Science, Ministry of Health of the People's Republic of China, Wenzhou, Zhejiang, China.
authors.forename: Qinmei
authors.initials: Q
authors.lastname: Wang
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang 325027, China ; Key Laboratory of Vision Science, Ministry of Health of the People's Republic of China, Wenzhou, Zhejiang, China.
authors.forename: Jinhai
authors.initials: J
authors.lastname: Huang