title: Cryptococcosis Presenting as a Colonic Ulcer in a Kidney Transplant Recipient: A Case Report.
abstract: We present a case of a 59-year-old woman with Chagas disease who received a kidney transplant. At month 44 post-transplantation, the patient presented with diarrhea that had persisted for 2 months. Colonoscopy showed a colon ulcer and differential diagnoses included cytomegalovirus, bacteria, or parasite infection; drug-related diarrhea; Crohn's disease; celiac disease; and malignancy. The ulcer tissue was positive for Cryptococcus neoformans. Successful treatment consisted of amphotericin B for 8 days and oral fluconazole (800 mg daily) for 3 months. This case illustrates that a colonic ulcer, although rare, could be cryptococcosis.
authors.affiliation: Renal Transplantation, Hospital de Alta Complejidad Pte JD Perón, Formosa, Argentina; Foundation for Research and Assistance of Kidney Disease, Buenos Aires, Argentina.
authors.forename: F
authors.initials: F
authors.lastname: Cicora
authors.affiliation: Renal Transplantation, Hospital de Alta Complejidad Pte JD Perón, Formosa, Argentina.
authors.forename: J
authors.initials: J
authors.lastname: Petroni
authors.affiliation: Foundation for Research and Assistance of Kidney Disease, Buenos Aires, Argentina. Electronic address: javierroberti@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Roberti
mesh_terms: D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage; D003108:Colonic Diseases / Q000175:diagnosis / Q000382:microbiology*; D003453:Cryptococcosis / Q000382:microbiology*; D003455:Cryptococcus neoformans; D003937:Diagnosis, Differential; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D014456:Ulcer / Q000175:diagnosis / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole