title: The State of the Orbitofrontal Cortex.
abstract: State representation is fundamental to behavior. However, identifying the true state of the world is challenging when explicit cues are ambiguous. Here, Bradfield and colleagues show that the medial OFC is critical for using associative information to discriminate ambiguous states.
authors.affiliation: National Institute on Drug Abuse, Baltimore, MD 21224, USA; Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA. Electronic address: melissa.sharpe@nih.gov.
authors.forename: Melissa J
authors.initials: MJ
authors.lastname: Sharpe
authors.affiliation: National Institute on Drug Abuse, Baltimore, MD 21224, USA.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Wikenheiser
authors.affiliation: Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Department of Psychology, Princeton University, Princeton, NJ 08544, USA.
authors.forename: Yael
authors.initials: Y
authors.lastname: Niv
authors.affiliation: National Institute on Drug Abuse, Baltimore, MD 21224, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Solomon H. Snyder Department of Neuroscience, The John Hopkins University, Baltimore, MD 21218, USA. Electronic address: geoffrey.schoenbaum@nih.gov.
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Schoenbaum
mesh_terms: D000818:Animals; D002755:Choice Behavior / Q000502:physiology*; D008297:Male; D017397:Prefrontal Cortex / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D012201:Reward