title: Iodine(III)-Mediated Oxidative Hydrolysis of Haloalkenes: Access to α-Halo Ketones by a Release-and-Catch Mechanism.
abstract: An unprecedented iodine(III)-mediated oxidative transposition of vinyl halides has been accomplished. The products obtained, α-halo ketones, are useful and polyvalent synthetic precursors. There are only a handful of reported examples of the direct conversion of vinyl halides to their corresponding α-halo carbonyl compounds. Insights into the mechanism and demonstration that this synthetic transformation can be done under enantioselective conditions are reported.
authors.affiliation: University of Sherbrooke , Department of Chemistry, Centre in Green Chemistry and Catalysis, 2500 boul. de l'Université, Sherbrooke, Québec J1K 2R1, Canada.
authors.forename: Antoine
authors.initials: A
authors.lastname: Jobin-Des Lauriers
authors.affiliation: University of Sherbrooke , Department of Chemistry, Centre in Green Chemistry and Catalysis, 2500 boul. de l'Université, Sherbrooke, Québec J1K 2R1, Canada.
authors.forename: Claude Y
authors.initials: CY
authors.lastname: Legault