title: Not All Created Equal: Lineage Hard-Wiring in the Production of Blood.
abstract: The multiple cell types comprising blood have been thought to emerge from progenitors with progressively narrower lineage options. New data suggest that lineage fate may be determined earlier than thought and that myeloid progenitor populations are aggregates of individual lineage-restricted cells.
authors.affiliation: Center for Regenerative Medicine and Cancer Center, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Harvard Stem Cell Institute and Harvard University Department of Stem Cell and Regenerative Biology, 7 Divinity Avenue, Cambridge, MA 02138, USA.
authors.forename: Francois E
authors.initials: FE
authors.lastname: Mercier
authors.affiliation: Center for Regenerative Medicine and Cancer Center, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Harvard Stem Cell Institute and Harvard University Department of Stem Cell and Regenerative Biology, 7 Divinity Avenue, Cambridge, MA 02138, USA. Electronic address: david_scadden@harvard.edu.
authors.forename: David T
authors.initials: DT
authors.lastname: Scadden
mesh_terms: D000818:Animals; D019070:Cell Lineage; D006410:Hematopoiesis; D023461:Myeloid Progenitor Cells / Q000166:cytology* / Q000378:metabolism*; D059010:Single-Cell Analysis; D059467:Transcriptome