title: Rat Models of Acute and/or Chronic Peritoneal Injuries Including Peritoneal Fibrosis and Peritoneal Dialysis Complications.
abstract: Peritoneal injury is a major cause of discontinuation from long-term peritoneal dialysis. However, the precise mechanisms underlying such injury remain unclear. Suitable animal models of peritoneal injury may be useful to analyze pathogenic mechanisms and facilitate the development of therapeutic approaches. We describe herein two rat models of peritoneal injury that we have recently proposed.
authors.affiliation: Renal Replacement Therapy, Division of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Japan. mmizu@med.nagoya-u.ac.jp.
authors.forename: Masashi
authors.initials: M
authors.lastname: Mizuno
authors.affiliation: Renal Replacement Therapy, Division of Nephrology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Ito
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D007150:Immunohistochemistry / Q000379:methods; D010530:Peritoneal Dialysis / Q000009:adverse effects* / Q000379:methods; D010532:Peritoneal Diseases / Q000209:etiology* / Q000473:pathology*; D056627:Peritoneal Fibrosis / Q000209:etiology / Q000473:pathology; D010538:Peritonitis / Q000209:etiology / Q000473:pathology; D051381:Rats
keywords: Fibrosis; Peritoneal dialysis; Peritoneal injuries; Zymosan