title: [Phantom Study on Dose Reduction Using Iterative Reconstruction in Low-dose Computed Tomography for Lung Cancer Screening].
abstract: We investigated dose reduction ability of an iterative reconstruction technology for low-dose computed tomography (CT) for lung cancer screening. The Sinogram Affirmed Iterative Reconstruction (SAFIRE) provided in a multi slice CT system, Somatom Definition Flash (Siemens Healthcare) was used. An anthropomorphic chest phantom (N-1, Kyoto Kagaku) was scanned at volume CT dose index (CTDIvol) of 0.50-11.86 mGy with 120 kV. For noise (standard deviation) and contrast-to-noise ratio (CNR) measurements, CTP486 and CTP515 modules in the Catphan (The Phantom Laboratory) were scanned. Radiological technologists were participated in the perceptual comparison. SAFIRE reduced the SD values by approximately 50% compared with filter back projection (FBP). The estimated dose reduction rates by SAFIRE determined from the perceptual comparison was approximately 23%, while 75% dose reduction rate was expected from the SD value reduction of 50%.
authors.affiliation: Department of Radiology, Kanazawa University Hospital.
authors.forename: Kaori
authors.initials: K
authors.lastname: Minehiro
authors.forename: Tadanori
authors.initials: T
authors.lastname: Takata
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hayashi
authors.forename: Keita
authors.initials: K
authors.lastname: Sakuda
authors.forename: Haruka
authors.initials: H
authors.lastname: Nunome
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kawashima
authors.forename: Shigeru
authors.initials: S
authors.lastname: Sanada
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D014057:Tomography, X-Ray Computed