title: Patient and Technique Survival of Older Adults with ESRD Treated with Peritoneal Dialysis.
abstract: The number of older adults worldwide is increasing as societies gain success in improving the health and lifespan of their citizens. As a result, increasing numbers of older adults are presenting to the medical community with advanced kidney failure. Historically, dialysis treatments were withheld from older adults particularly those with severe co-existing illnesses. This has changed in most parts of the world, and there is now an increasing emphasis on shared decision-making to determine whether dialysis is appropriate and to determine which modality meets the needs, expectations, and desire of patients. Evidence examining the difference in risk for death of older adults treated with hemodialysis (HD) or peritoneal dialysis (PD), and the probability of those treated with PD to transfer to HD among older compared to younger adults, is largely derived from prospective cohort studies or analyses of data from national registries. In such studies, it is difficult to distinguish whether differences in outcomes reflect the effect of dialysis modality or differences in health status of different groups of patients. Longevity and technique survival are important, albeit not the only or most important consideration in such decision-making. Given the risk for bias in observational studies and the profound effect of dialysis modality on patients' lifestyle, the selection of dialysis modality should remain a decision made by the patient, caregivers, and his/her physician after thorough education and review of the available data.
authors.affiliation: Nephrology, University of Washington, Seattle, WA, USA scbieber@u.washington.edu.
authors.forename: Scott D
authors.initials: SD
authors.lastname: Bieber
authors.affiliation: Nephrology, University of Washington, Seattle, WA, USA.
authors.forename: Rajnish
authors.initials: R
authors.lastname: Mehrotra
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000553:Ambulatory Care / Q000379:methods; D002423:Cause of Death; D005260:Female; D006436:Hemodialysis Units, Hospital / Q000706:statistics & numerical data; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000009:adverse effects / Q000379:methods* / Q000401:mortality*; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D018570:Risk Assessment; D016019:Survival Analysis; D014481:United States
keywords: Peritoneal dialysis; elderly; mortality; patient survival; survival; technique survival