title: Brain abscess due to Aggregatibacter aphrophilus and Bacteroides uniformis.
abstract: OBJECTIVE
  The aim of this report was to describe the occurrence of a bacterial brain abscess in a healthy individual, without any predisposing condition.
  
  
  METHODS
  A thirteen-year old boy was admitted to the Department of Neurosurgery after the onset of vomiting, headache and dizziness. A neurological deficit was detected during the physical examination so urgent magnetic resonance imaging of the brain was performed, revealing an intrahemispheric, right positioned solitary expansive mass with ring enhancement. Purulent material was obtained during osteoplastic craniotomy with total extirpation of the brain abscess. Aggregatibacter aphrophilus and Bacteroides uniformis were isolated. The patient's general condition improved and the neurological deficit subsided as a result of the prompt recognition and treatment of this life threatening condition.
  
  
  CONCLUSIONS
  To achieve a favourable clinical outcome, prompt recognition and surgical treatment of a brain abscess are of primary importance,followed by administration of appropriate antimicrobial therapy. To our best knowledge, this is the first report of this combination of microorganisms as the cause of a brain abscess.
authors.affiliation: Institute of Public Health for the Osijek-Baranja County, Department of Microbiology, Osijek, Croatia. maja.bogdan7@gmail.com.
authors.forename: Maja
authors.initials: M
authors.lastname: Bogdan
authors.affiliation: Institute of Public Health for the Osijek-Baranja County, Department of Microbiology, Osijek, Croatia.
authors.forename: Vlasta
authors.initials: V
authors.lastname: Zujić Atalić
authors.affiliation: University Hospital Center Osijek, Department of Neurosurgery, Osijek, Croatia; University "J. J. Strossmayer", School of Medicine, Department of Neurosurgery, Osijek, Croatia.
authors.forename: Ivan
authors.initials: I
authors.lastname: Hećimović
authors.affiliation: Institute of Public Health for the Osijek-Baranja County, Department of Microbiology, Osijek, Croatia.
authors.forename: Dubravka
authors.initials: D
authors.lastname: Vuković
mesh_terms: D000293:Adolescent; D064207:Aggregatibacter aphrophilus / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001439:Bacteroides / Q000302:isolation & purification; D001442:Bacteroides Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D001922:Brain Abscess / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D020682:Cefixime / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D060085:Coinfection; D003399:Craniotomy; D004322:Drainage; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D016871:Pasteurellaceae Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole; D002443:Ceftriaxone; D020682:Cefixime