title: Expression Pattern of p27 Protein in Primary Gastric Lymphomas.
abstract: OBJECTIVE
  To investigate the expression pattern of p27 protein in primary gastric lymphomas.
  
  
  METHODS
  Immunostaining for the p27 protein was performed in 16 cases of low grade mucosa-associated lymphoid tissue (MALT) lymphomas and 16 cases of high grade B-cell lymphomas of the stomach.
  
  
  RESULTS
  All low grade MALT lymphomas were positive, however all high grade lymphomas were negative forp27 protein. Most of the monocytoid cells in the low grade lymphoma were unstained.
  
  
  CONCLUSIONS
  Loss of p27 protein expression is well correlated with histologic grade and appears to be associated with the high grade transformation seen in primary gastric lymphomas.
authors.forename: J H
authors.initials: JH
authors.lastname: Go
keywords: Lymphoma; Stomach; p27 protein