title: Radiographic and Pathologic Manifestations of Uncommon and Rare Pulmonary Lesions.
abstract: Pulmonary opacities/nodules are common findings on computed tomography examinations, which may represent an underlying infections or malignancy. However, not every pulmonary nodule or opacity represents malignancy or infection. We present a pictorial essay illustrating common as well as obscure noninfectious, nonmalignant pulmonary lesions. Lesions discussed include organizing pneumonia, Langerhans cell histiocytosis, pulmonary amyloidosis, hyalinizing granuloma, tumourlet (benign localized neuroendocrine cell proliferations), atypical alveolar hyperplasia, inflammatory myofibroblastic tumour, papillary alveolar adenoma, plasma cell granuloma, juvenile xanthogranuloma, and sclerosing hemangiomas. We discuss the clinical presentation, prevalence, radiographic clues, pathology, and diagnostic pitfalls of these rare lesions.
authors.affiliation: Department of Radiology, Yale New Haven Hospital, New Haven, Connecticut, USA. Electronic address: kpfeife@gmail.com.
authors.forename: Kyle
authors.initials: K
authors.lastname: Pfeifer
authors.affiliation: Department of Radiology, Yale New Haven Hospital, New Haven, Connecticut, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Mian
authors.affiliation: Department of Pathology, Yale New Haven Hospital, New Haven, Connecticut, USA.
authors.forename: Adeniran
authors.initials: A
authors.lastname: Adebowale
authors.affiliation: Department of Pathology, Yale New Haven Hospital, New Haven, Connecticut, USA.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Alomari
authors.affiliation: Department of Radiology, Yale New Haven Hospital, New Haven, Connecticut, USA.
authors.forename: Vivek
authors.initials: V
authors.lastname: Kalra
authors.affiliation: Department of Pathology, Lawrence and Memorial Hospital, New London, Connecticut, USA.
authors.forename: Elise
authors.initials: E
authors.lastname: Krejci
authors.affiliation: Department of Radiology, Yale New Haven Hospital, New Haven, Connecticut, USA.
authors.forename: Myung Soo
authors.initials: MS
authors.lastname: Shin
mesh_terms: D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008171:Lung Diseases / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed
keywords: Atypical alveolar hyperplasia; Computed tomography; Hyalinizing granuloma; Inflammatory myofibrolastic tumour; Juvenile xanthogranuloma; Langerhans cell histiocytosis; Organizing pneumonia; Papillary alveolar adenoma; Plasma cell granuloma; Pulmonary amyloidosis; Pulmonary nodule; Sclerosing hemangiomas; Tumourlet