title: Rat and poultry feeding studies with soybean meal produced from imidazolinone-tolerant (CV127) soybeans.
abstract: The safety and nutritional properties of CV127 soybeans were evaluated in rat and broiler feeding studies. Some episodic differences were observed between rats fed CV127, Conquista, and the standard diet for the endpoints examined. None of these differences were considered treatment related, adverse, or biologically meaningful. In general, birds fed diets containing CV127, Conquista, or Monsoy 8001 showed no significant differences in growth and performance response variables. Chickens fed diets containing Coodetec 217 had lower body weight and weight gain for all developmental periods compared to CV127, but no significant differences were found in feed conversion for the two diets during any development period. The results of both feeding studies demonstrate that CV127 soybeans are as safe, wholesome, and nutritionally valuable as the other soybean meals tested, including those varieties for which histories of safe use have been established and well documented.
authors.affiliation: China Agricultural University, Supervision and Testing Center for Genetically Modified Organisms Food Safety, Ministry of Agriculture, Beijing, China.
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: He
authors.affiliation: Embrapa Swine and Poultry, Concórdia, Santa Catarina, Brazil.
authors.forename: Paulo A R
authors.initials: PA
authors.lastname: de Brum
authors.affiliation: BASF Corporation, 26 Davis Drive, Research Triangle Park, NC 27709, USA.
authors.forename: Amechi
authors.initials: A
authors.lastname: Chukwudebe
authors.affiliation: BASF Plant Science LP, 26 Davis Drive, Research Triangle Park, NC 27709, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Privalle
authors.affiliation: BASF Plant Science LP, 26 Davis Drive, Research Triangle Park, NC 27709, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Reed
authors.affiliation: BASF China, 25/F, Tower A, Gateway Plaza, 100027 Beijing, China.
authors.forename: Yanqing
authors.initials: Y
authors.lastname: Wang
authors.affiliation: China Agricultural University, Supervision and Testing Center for Genetically Modified Organisms Food Safety, Ministry of Agriculture, Beijing, China.
authors.forename: Cui
authors.initials: C
authors.lastname: Zhou
authors.affiliation: China Agricultural University, Supervision and Testing Center for Genetically Modified Organisms Food Safety, Ministry of Agriculture, Beijing, China.
authors.forename: Cuiyan
authors.initials: C
authors.lastname: Wang
authors.affiliation: China Agricultural University, Supervision and Testing Center for Genetically Modified Organisms Food Safety, Ministry of Agriculture, Beijing, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Lu
authors.affiliation: China Agricultural University, Supervision and Testing Center for Genetically Modified Organisms Food Safety, Ministry of Agriculture, Beijing, China.
authors.forename: Kunlun
authors.initials: K
authors.lastname: Huang
authors.affiliation: BASF South America, Av. das Nações Unidas, 14.171, 14° andar, 04794-000 Sao Paulo, Brazil.
authors.forename: Daniela
authors.initials: D
authors.lastname: Contri
authors.affiliation: BASF South America, Av. das Nações Unidas, 14.171, 14° andar, 04794-000 Sao Paulo, Brazil.
authors.forename: Andreia
authors.initials: A
authors.lastname: Nakatani
authors.affiliation: Embrapa Swine and Poultry, Concórdia, Santa Catarina, Brazil.
authors.forename: Valdir S
authors.initials: VS
authors.lastname: de Avila
authors.affiliation: Embrapa Swine and Poultry, Concórdia, Santa Catarina, Brazil.
authors.forename: Claudete H
authors.initials: CH
authors.lastname: Klein
authors.affiliation: Embrapa Swine and Poultry, Concórdia, Santa Catarina, Brazil.
authors.forename: Gustavo J M M
authors.initials: GJ
authors.lastname: de Lima
authors.affiliation: BASF Plant Science LP, 26 Davis Drive, Research Triangle Park, NC 27709, USA. Electronic address: elizabeth.lipscomb@basf.com.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Lipscomb
mesh_terms: D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D002645:Chickens; D004032:Diet / Q000662:veterinary*; D004334:Drug Administration Schedule; D004906:Erythrocyte Count; D005260:Female; D006400:Hematocrit; D006540:Herbicides / Q000633:toxicity*; D007958:Leukocyte Count; D008297:Male; D030821:Plants, Genetically Modified; D051381:Rats; D017207:Rats, Sprague-Dawley; D013025:Glycine max / Q000235:genetics* / Q000502:physiology*
chemical_list: D006540:Herbicides
keywords: Acetohydroxyacid synthase; Broiler study; Genetically modified crop; Herbicide-tolerant crop; Nutritional study; Subchronic feeding study