title: Systemic Coronaviral Disease in 5 Ferrets.
abstract: The prevalence of reported systemic coronaviral disease in ferrets (Mustela putorius furo), which resembles the dry form of feline infectious peritonitis, has been increasing in the literature since its initial diagnosis and characterization approximately 10 y ago. Here we describe the clinical signs, pathologic findings, and diagnosis by immunohistochemistry using an FIPV3-70 monoclonal antibody of systemic coronaviral disease in 5 ferrets, 2 of which were strictly laboratory-housed; the remaining 3 were referred from veterinary private practices. This case report illustrates the importance of considering FRSCV infection as a differential diagnosis in young, debilitated ferrets with abdominal masses and other supporting clinical signs.
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Autieri
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, SNBL USA, Everett, Washington, USA.
authors.forename: Cassandra L
authors.initials: CL
authors.lastname: Miller
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
authors.forename: Kathleen E
authors.initials: KE
authors.lastname: Scott
authors.affiliation: Littleton Animal Hospital, Littleton, Massachusetts, USA.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Kilgore
authors.affiliation: Littleton Animal Hospital, Littleton, Massachusetts, USA.
authors.forename: Victoria A
authors.initials: VA
authors.lastname: Papscoe
authors.affiliation: Northwest ZooPath, Monroe, Washington, USA.
authors.forename: Michael M
authors.initials: MM
authors.lastname: Garner
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Haupt
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
authors.forename: Vasudevan
authors.initials: V
authors.lastname: Bakthavatchalu
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
authors.forename: Sureshkumar
authors.initials: S
authors.lastname: Muthupalani
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. jgfox@mit.edu.
authors.forename: James G
authors.initials: JG
authors.lastname: Fox
mesh_terms: D000818:Animals; D018352:Coronavirus Infections / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D005289:Ferrets; D008297:Male