title: Disposable Non-Enzymatic Glucose Sensors Using Screen-Printed Nickel/Carbon Composites on Indium Tin Oxide Electrodes.
abstract: Disposable screen-printed nickel/carbon composites on indium tin oxide (ITO) electrodes (DSPNCE) were developed for the detection of glucose without enzymes. The DSPNCE were prepared by screen-printing the ITO substrate with a 50 wt% nickel/carbon composite, followed by curing at 400 °C for 30 min. The redox couple of Ni(OH)₂/NiOOH was deposited on the surface of the electrodes via cyclic voltammetry (CV), scanning from 0-1.5 V for 30 cycles in 0.1 M NaOH solution. The DSPNCE were characterized by field-emission scanning electron microscopy (FE-SEM), X-ray photoelectron spectroscopy (XPS), and electrochemical methods. The resulting electrical currents, measured by CV and chronoamperometry at 0.65 V vs. Ag/AgCl, showed a good linear response with glucose concentrations from 1.0-10 mM. Also, the prepared electrodes showed no interference from common physiologic interferents such as uric acid (UA) or ascorbic acid (AA). Therefore, this approach allowed the development of a simple, disposable glucose biosensor.
authors.affiliation: Department of Nanobiomedical Sciences and BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Anseo-Dong, Cheonan, Chungnam 330-714, Korea. powerwy@hanmail.net.
authors.forename: Won-Yong
authors.initials: WY
authors.lastname: Jeon
authors.affiliation: Department of Chemistry, College of Natural Science, Dankook University, Anseo-Dong, Cheonan, Chungnam 330-714, Korea. chem0404@dankook.ac.kr.
authors.forename: Young-Bong
authors.initials: YB
authors.lastname: Choi
authors.affiliation: Department of Nanobiomedical Sciences and BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Anseo-Dong, Cheonan, Chungnam 330-714, Korea. hankim@dankook.ac.kr.|Department of Chemistry, College of Natural Science, Dankook University, Anseo-Dong, Cheonan, Chungnam 330-714, Korea. hankim@dankook.ac.kr.
authors.forename: Hyug-Han
authors.initials: HH
authors.lastname: Kim
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D002244:Carbon / Q000737:chemistry; D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D009532:Nickel / Q000737:chemistry*; D013499:Surface Properties; D017971:Tin Compounds / Q000737:chemistry*
chemical_list: D017971:Tin Compounds; C109984:indium tin oxide; D002244:Carbon; D009532:Nickel; D005947:Glucose
keywords: biosensor; disposable glucose sensor; nickel/carbon composite; non-enzymatic glucose sensor