title: [Study of clinical characteristics and curative effects of sudden hearing loss patients with vertigo].
abstract: OBJECTIVE
  To analyze the clinical characteristics, prognosis and therapeutic effects of sudden sensorineural hearing loss (SSHL) patients associated with vertigo, and to investigate the strategy of diagnosis and treatment.
  
  
  METHODS
  We retrospectively analyzed the clinical characteristics of 240 patients diagnosed as SSHL with vertigo, who were treated in the Chinese PLA General Hospital from July 2008 to August 2012. Various factors affecting the therapeutic effects were analyzed, such as audiological features, vestibular function tests, genders, audiograms, lasting before seeing a doctor, courses of vertigo and vascular factors.
  
  
  RESULTS
  Among the contemporaneous SSHL patients (873 cases), the cases with vertigo accounted for 27.49% (240/873). Among the 240 patients with vertigo, the cases with different hearing impaired degree of mild, moderate, severe and profound were 30, 13, 28 and 34, respectively, primarily by the profound cases. Detailed vestibular function tests were performed in 97 patients, with 54 cases having unilateral vestibular disfunction and 43 patients having normal vestibular function, among which 23 cases were diagnosed as benign paroxymal positional vertigo (BBPV). The relationship between vestibular function and different hearing impaired degrees or various audiogram types had no statistically significant difference. 219 cases had detailed records of the onset time of cochlear and vestibular symptoms, including 122 patients with cochlear symptoms and dizziness occurring simultaneously. After standardized drug treatment, the total effective rate was 46.67%, with recovery in 17 cases, excellent in 34 cases, better in 61 cases and poor in 128 cases, respectively. Statistical analysis showed that different genders, audiogram types, vertigo courses of time, the results of vestibular function and neck vascular ultrasounds were not related to the curative effects, while, the treatment time after onset was significantly associated with treatment effects.
  
  
  CONCLUSIONS
  SSHL with vertigo has a high incidence, primarily single side affected, with relatively severe hearing impairment, and total deafness and downslope hearing curve mainly. Vestibular function can be normal or low in SSHL patients with vertigo, with a higher incidence of BPPV. Vestibular and cochlear symptoms occur simultaneously in more than half of the patients. The detection rate of vestibular dysfunction gradually increased, as the degree of hearing loss increased, without statistical significance although. The therapeutic effects of sudden hearing loss with vertigo cases have no relationship with dizziness duration or vestibular function, while the disease course plays an important role in treatment.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Gao
authors.forename: Dayong
authors.initials: D
authors.lastname: Wang
authors.forename: Qin
authors.initials: Q
authors.lastname: Su
authors.forename: Hongyang
authors.initials: H
authors.lastname: Wang
authors.forename: Lan
authors.initials: L
authors.lastname: Lan
authors.forename: Zifang
authors.initials: Z
authors.lastname: Yin
authors.forename: Lan
authors.initials: L
authors.lastname: Yu
authors.forename: Ziming
authors.initials: Z
authors.lastname: Wu
authors.forename: Xizheng
authors.initials: X
authors.lastname: Shan
authors.forename: Xijun
authors.initials: X
authors.lastname: Xue
authors.affiliation: Email: wqcr@263.net.
authors.forename: Qiuju
authors.initials: Q
authors.lastname: Wang
mesh_terms: D065635:Benign Paroxysmal Positional Vertigo / Q000150:complications*; D003051:Cochlea / Q000503:physiopathology; D003638:Deafness; D004244:Dizziness; D006319:Hearing Loss, Sensorineural; D003639:Hearing Loss, Sudden / Q000150:complications*; D006320:Hearing Tests; D006801:Humans; D011379:Prognosis; D012189:Retrospective Studies; D014724:Vestibular Function Tests; D014722:Vestibule, Labyrinth / Q000503:physiopathology