title: Guided Bone Regeneration Using Demineralized Dentin Matrix: Long-Term Follow-Up.
abstract: OBJECTIVE
  This case report reviews the long-term clinical outcomes of using demineralized dentin matrix (autogenous tooth bone graft material [AutoBT]) in 5 cases that were first reported in 2010.
  
  
  METHODS
  Cone-beam computerized tomography was used to measure the height and width of the graft to determine the change in bone area from immediately after surgery to final follow-up (average, 5 yr 5.8 months). Corticocancellous bone formation and marginal bone resorption also were evaluated histologically 3 to 6 months after grafting, which focused mainly on remodeling capacities.
  
  
  RESULTS
  Decreases in buccal height and alveolar ridge width ranged from -0.4 to -3.3 mm and from -0.4 to -4.2 mm, respectively. The change in bone area ranged from -8.1 to -36.2%. Corticocancellous bone had formed and was maintained successfully except for 1 mm of buccal marginal bone resorption in 1 case followed for 6 years 7 months.
  
  
  CONCLUSIONS
  AutoBT, which was first reported for guided bone regeneration, showed that the corticocancellous bone that had formed had been maintained successfully with an implant after an average follow-up of 5 years. Although the number of samples was small, the results were consistent with those of other short-term follow-up studies on AutoBT.
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam; Professor, Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Young-Kyun
authors.initials: YK
authors.lastname: Kim
authors.affiliation: Professor, Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University; and Professor, Department of Oral and Maxillofacial Surgery, Seoul National University Dental Hospital, Seoul, Korea.
authors.forename: Jong-Ho
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Director, R&D Institute, Korea Tooth Bank, Seoul, Korea. Electronic address: h-bmp@hanmail.net.
authors.forename: In-Woong
authors.initials: IW
authors.lastname: Um
authors.affiliation: Researcher, R&D Institute, Korea Tooth Bank, Seoul, Korea.
authors.forename: Woo-Jin
authors.initials: WJ
authors.lastname: Cho
mesh_terms: D000328:Adult; D000539:Alveolar Process / Q000000981:diagnostic imaging; D001861:Bone Regeneration / Q000502:physiology*; D016723:Bone Remodeling / Q000502:physiology; D001862:Bone Resorption / Q000503:physiopathology; D054893:Cone-Beam Computed Tomography / Q000379:methods; D003758:Dental Implantation, Endosseous / Q000379:methods; D003804:Dentin / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D048091:Guided Tissue Regeneration / Q000379:methods*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010012:Osteogenesis / Q000502:physiology; D016896:Treatment Outcome
chemical_list: C093073:Demineralized Dentin Matrix