title: [Contribution of a halogen bond to binding of halogenated ligands by protein kinases].
abstract: This article presents a brief overview of recent studies on the phenomena of halogen bonding, most of which have been done for the last 15 years in the collaboration with Prof. David Shugar. All these investigations concern reliable estimation of the thermodynamic contribution of a halogen bond to protein-ligand interactions.
authors.forename: Jarosław
authors.initials: J
authors.lastname: Poznański
mesh_terms: D001671:Biochemistry / Q000266:history*; D004791:Enzyme Inhibitors / Q000266:history; D006219:Halogens / Q000266:history; D049673:History, 20th Century; D049674:History, 21st Century; D008024:Ligands; D011044:Poland; D011485:Protein Binding; D011494:Protein Kinases / Q000737:chemistry / Q000266:history* / Q000378:metabolism
chemical_list: D004791:Enzyme Inhibitors; D006219:Halogens; D008024:Ligands; D011494:Protein Kinases