title: Impact of treatment strategies for open angle glaucoma on intraocular pressure: the RiGOR study.
abstract: OBJECTIVE
  The RiGOR study's primary outcome measure was a 15% reduction in intraocular pressure (IOP) for patients with open-angle glaucoma at 1 year.
  
  
  METHODS
  Patients received treatment according to the ophthalmologist's usual practice.
  
  
  RESULTS
  A higher proportion of patients in the incisional and other surgery group achieved a 15% reduction in IOP than in the laser surgery or additional medication groups (82, 57, and 57% respectively). In multivariate regression analyses, incisional surgery patients were 2.7-times as likely as patients treated with additional medication to achieve a 15% reduction in IOP (odds ratio: 2.67; 95% CI: 2.01-3.57).
  
  
  CONCLUSIONS
  Incisional and other surgical procedures are effective treatments. There were no differences in treatment response by race or ethnicity.
authors.affiliation: Jules Stein Eye Institute, David Geffen School of Medicine & Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA.|H Dunbar Hoskins, Jr MD Center for Quality Eye Care, Foundation of the American Academy of Ophthalmology, 655 Beach Street, San Francisco, CA 94109, USA.
authors.forename: Anne L
authors.initials: AL
authors.lastname: Coleman
authors.affiliation: H Dunbar Hoskins, Jr MD Center for Quality Eye Care, Foundation of the American Academy of Ophthalmology, 655 Beach Street, San Francisco, CA 94109, USA.
authors.forename: Flora C
authors.initials: FC
authors.lastname: Lum
authors.affiliation: Outcome DEcIDE Center, Quintiles Real World & Late Phase Research, Cambridge, MA 02139, USA.
authors.forename: Priscilla
authors.initials: P
authors.lastname: Velentgas
authors.affiliation: Outcome DEcIDE Center, Quintiles Real World & Late Phase Research, Cambridge, MA 02139, USA.
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Su
authors.affiliation: Massachusetts Eye & Ear & Harvard Medical School, Boston, MA 02114, USA.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Gliklich
mesh_terms: D058647:Adrenergic alpha-2 Receptor Agonists / Q000627:therapeutic use; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044383:Black People / Q000706:statistics & numerical data; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology* / Q000628:therapy*; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects / Q000502:physiology*; D053685:Laser Therapy / Q000379:methods; D008297:Male; D008875:Middle Aged; D010277:Parasympathomimetics / Q000627:therapeutic use; D011465:Prostaglandins, Synthetic / Q000627:therapeutic use; D014130:Trabeculectomy; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D000319:Adrenergic beta-Antagonists; D002257:Carbonic Anhydrase Inhibitors; D010277:Parasympathomimetics; D011465:Prostaglandins, Synthetic
keywords: comparative effectiveness; glaucoma medication; glaucoma surgery; intraocular pressure; open-angle glaucoma; registry