title: Clinical Features of Miller-Fisher Syndrome in Pregnancy.
abstract: Miller-Fisher syndrome (MFS) is recognized as a variant of Guillain-Barré syndrome (GBS). MFS is a rare disorder that is characterized by the acute onset of ophthalmoplegia, ataxia, and areflexia/hyporeflexia. MFS has a higher incidence in Asia, where the incidence is estimated to be 18%-26% of GBS compared with 3%-5% in the West. The differential diagnosis of MFS includes Wernicke's encephalopathy (WE) which is characterized by a clinical triad (nystagmus and ophthalmoplegia, mental status changes, and ataxia), myasthenia gravis, and brainstem stroke. The association between MFS and pregnancy has not been reported previously. Here, we describe the clinical features of a pregnant woman in early pregnancy with MFS. This case highlights the fact that it is necessary to establish an accurate diagnosis based on the details from the patient's history on appropriate complementary testing in a pregnant patient with MFS.
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Masanori
authors.initials: M
authors.lastname: Ono
authors.affiliation: Department of Neurology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Sato
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Mayu
authors.initials: M
authors.lastname: Shirahashi
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Tomioka
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Julia
authors.initials: J
authors.lastname: Maeda
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Watanabe
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Amagata
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Ikeda
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Kazumi
authors.initials: K
authors.lastname: Yakubo
authors.affiliation: Department of Obstetrics and Gynecology, Saitama City Hospital, Midori, Saitama 336-8522, Japan.
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Fukuiya