title: Effect of lead pollution on fitness and its dependence on heterozygosity in Drosophila subobscura.
abstract: Lead is one of the most present contaminants in the environment, and different species respond differently to this type of polution. If combined with genomic stress, lead may act synergistically, causing significant decrease of fitness components. We used two genetically diverse Drosophila subobscura populations (regarding both putatively adaptive inversion and microsatellite loci polymorphisms) originating from two ecologically distinct habitats. To establish different levels of genome heterozygosity, series of intraline, intrapopulation and interpopulation crosses were made. The progeny were reared on a standard medium and a medium with 200 μg/mL of lead acetate. Development time was significantly extended to all groups reared on lead. The progeny of intraline crosses showed significantly extended development time compared to all other groups. The obtained results suggest that genome heterozygosity reduces the effect of lead pollution.
authors.affiliation: Faculty of Biology, University of Belgrade, Studentski Trg 3, 11000 Belgrade, Republic of Serbia. marija.tanaskovic@bio.bg.ac.rs.
authors.forename: Marija
authors.initials: M
authors.lastname: Tanaskovic
authors.forename: Zorana Kurbalija
authors.initials: ZK
authors.lastname: Novicic
authors.forename: Bojan
authors.initials: B
authors.lastname: Kenig
authors.forename: Marina
authors.initials: M
authors.lastname: Stamenkovic-Radak
authors.forename: Marko
authors.initials: M
authors.lastname: Andjelkovic
mesh_terms: D000818:Animals; D004330:Drosophila / Q000187:drug effects* / Q000235:genetics*; D017753:Ecosystem; D004777:Environment; D005828:Genetics, Population / Q000379:methods; D006579:Heterozygote; D007854:Lead / Q000009:adverse effects*; D011110:Polymorphism, Genetic / Q000235:genetics*
chemical_list: D007854:Lead