title: Design, methodology and baseline characteristics of Tai Chi and its protective effect against ischaemic stroke risk in an elderly community population with risk factors for ischaemic stroke: a randomised controlled trial.
abstract: BACKGROUND
  Controlling risk factors with regular exercise is effective and cost-effective for the primary prevention of ischaemic stroke. As a traditional Chinese form of exercise, Tai Chi might be beneficial in decreasing ischaemic stroke, but the evidence remains insufficient. We hypothesise that elderly community adults with risk factors for ischaemic stroke will decrease their ischaemic stroke risk by improving cerebral haemodynamic parameters, cardiopulmonary function, motor function, plasma risk indices, physical parameters or psychological outcomes after receiving 12 weeks of regular Tai Chi training compared with those who maintained their original physical activities. Therefore, we designed a randomised controlled trial that will systematically evaluate the protective effects of Tai Chi exercise on ischaemic stroke risk in an elderly community population with risk factors for ischaemic stroke.
  
  
  METHODS
  A total of 170 eligible participants were randomly allocated into either the Tai Chi training group or the usual physical activity group. This paper reports on the design, intervention development and baseline characteristics of the participants. There were no significant differences between comparison groups in demographic characteristics or the baseline data of primary or secondary outcomes. Participants in the Tai Chi training group will receive 12 weeks of Tai Chi training with a frequency of 5 days/week and 60 min/day, while those in the usual physical activities group will maintain their original activities. Primary and secondary outcomes will be measured at the 12-week and 24-week follow-ups.
  
  
  BACKGROUND
  Ethical approval has been obtained from the Medical Ethics Committee of The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine (number 2013-020-02). The findings of this study will be communicated to healthcare professionals, participants and the public through peer-reviewed publications or scientific conferences.
  
  
  BACKGROUND
  ChiCTR-TRC-13003601; Pre-results.
authors.affiliation: College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
authors.forename: Guohua
authors.initials: G
authors.lastname: Zheng
authors.affiliation: College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Zheng
authors.affiliation: College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
authors.forename: Junzhe
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Physical Education, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
authors.forename: Tingjin
authors.initials: T
authors.lastname: Duan
authors.affiliation: Department of Physical Education, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
authors.forename: Dalu
authors.initials: D
authors.lastname: Qi
authors.affiliation: Department of Physical Education, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Ling
authors.affiliation: College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
authors.forename: Jian
authors.initials: J
authors.lastname: He
authors.affiliation: Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
authors.forename: Lidian
authors.initials: L
authors.lastname: Chen
mesh_terms: D000368:Aged; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D011446:Prospective Studies; D011788:Quality of Life; D012107:Research Design; D012111:Residence Characteristics; D012307:Risk Factors; D020521:Stroke / Q000517:prevention & control*; D026302:Tai Ji; D016896:Treatment Outcome
keywords: PREVENTIVE MEDICINE; SPORTS MEDICINE; STROKE MEDICINE