title: Effect of supplemental oxygen 80 % on post-tonsillectomy nausea and vomiting: a randomized controlled trial.
abstract: Nausea and vomiting are two of the most common complications of tonsillectomy in children. Administration of supplemental 80 % oxygen during surgery reduces the incidence of postoperative nausea and vomiting. We aimed to test the efficacy of supplemental 80 % oxygen during tonsillectomy on postoperative nausea and vomiting. In a randomized controlled trial in Shahid Mostafa Khomeini Hospital in Tehran, 102 children scheduled for tonsillectomy (± adenoidectomy) under general anesthesia were divided randomly in two groups according to percent of administered oxygen (group 1:30 % oxygen, group 2:80 % oxygen). The incidence of postoperative nausea and vomiting were assessed and compared in 0-2, 2-6 and 6-24 h after surgery. Incidence of post-tonsillectomy nausea and vomiting after 2, 2-6, and 6-24 h was 13.72, 1.96 and 1.96 % for group 1 and 3.92, 0 and 1.96 % in group 2, respectively. We found no statistically significant difference between two groups (P = 0.08) but 80 % oxygen was beneficial for reducing postoperative nausea and vomiting in the first 2 h after surgery in group 2.
authors.affiliation: Department of Otolaryngology, School of Medicine, Shahid Mostafa Khomeini Hospital, Shahed University, Italia Ave, Keshavarz Blvd, Tehran, 1466947893, Iran. popakizadi@yahoo.com.
authors.forename: Poopak
authors.initials: P
authors.lastname: Izadi
authors.affiliation: Department of Anaesthesiology, School of Medicine, Shahed University, Tehran, Iran.
authors.forename: Parvin
authors.initials: P
authors.lastname: Delavar
authors.affiliation: Department of Otolaryngology, School of Medicine, Shahid Mostafa Khomeini Hospital, Shahed University, Italia Ave, Keshavarz Blvd, Tehran, 1466947893, Iran.
authors.forename: Mohammad Ebrahim
authors.initials: ME
authors.lastname: Yarmohammadi
authors.affiliation: Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
authors.forename: Naimeh
authors.initials: N
authors.lastname: Daneshmandan
authors.affiliation: Shahed University, Tehran, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Sadrameli
mesh_terms: D000233:Adenoidectomy / Q000009:adverse effects; D000293:Adolescent; D000768:Anesthesia, General; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007492:Iran; D008297:Male; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology / Q000517:prevention & control*; D014068:Tonsillectomy / Q000009:adverse effects*
keywords: Nausea; Supplemental oxygen; Tonsillectomy; Vomiting