title: Implementation of a genetic logic circuit: bio-register.
abstract: We introduce an idea of synthesizing a class of genetic registers based on the existing sequential biological circuits, which are composed of fundamental biological gates. In the renowned literature, biological gates and genetic oscillator have been unveiled and experimentally realized in recent years. These biological circuits have formed a basis for realizing a primitive biocomputer. In the traditional computer architecture, there is an intermediate load-store section, i.e. a register, which serves as a part of the digital processor. With which, the processor can load data from a larger memory into it and proceed to conduct necessary arithmetic or logic operations. Then, manipulated data are stored back to the memory by instruction via the register. We propose here a class of bio-registers for the biocomputer. Four types of register structures are presented. In silicon experiments illustrate results of the proposed design.
authors.affiliation: Department of Electrical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
authors.forename: Chun-Liang
authors.identifier: 0000-0002-8520-3450
authors.initials: CL
authors.lastname: Lin
authors.affiliation: Department of Electrical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
authors.forename: Ting-Yu
authors.initials: TY
authors.lastname: Kuo
authors.affiliation: Department of Electrical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
authors.forename: Yang-Yi
authors.initials: YY
authors.lastname: Chen
keywords: Bio-computer; Bio-register; Genetic logic gate; Synthetic biology