title: Intractable colitis associated with chronic granulomatous disease in a young girl.
abstract: Chronic granulomatous disease (CGD) is an autosomal recessive or X-linked disorder caused by NADPH oxidase deficiency leading to an impaired ability of reactive superoxide anion and metabolite formation and recurring severe bacterial and fungal infections, with a high mortality rate. Diarrhea, colitis, ileus, perirectal abscess formation and anal fissures are reported gastrointestinal findings in these patients. We report a case of intractable colitis associated with CGD in a young girl.
authors.affiliation: Division of Pediatric Gastroenterology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey. aytacyaman@gmail.com.
authors.forename: Aytaç
authors.initials: A
authors.lastname: Yaman
authors.forename: Zarife
authors.initials: Z
authors.lastname: Kuloğlu
authors.forename: Figen
authors.initials: F
authors.lastname: Doğu
authors.forename: Aydan
authors.initials: A
authors.lastname: İkincioğulları
authors.forename: Arzu
authors.initials: A
authors.lastname: Ensari
authors.forename: Ergin
authors.initials: E
authors.lastname: Çiftçi
authors.forename: Aydan
authors.initials: A
authors.lastname: Kansu
mesh_terms: D002675:Child, Preschool; D003092:Colitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D019255:NADPH Oxidases / Q000172:deficiency
chemical_list: D019255:NADPH Oxidases