title: Neurologic Emergencies in the Patients With Cancer.
abstract: Neurologic complications of cancer are common and are frequently life-threatening events. Certain neurologic emergencies occur more frequently in the cancer population, specifically elevated intracranial pressure, epidural cord compression, status epilepticus, ischemic and hemorrhagic stroke, central nervous system infection, and treatment-associated neurologic dysfunction. These emergencies require early diagnosis and prompt treatment to ensure the best possible outcome and are best managed in the intensive care unit. This article reviews the presentation, pathophysiology, and management of the most common causes of acute neurologic decompensation in the patient with cancer.
authors.affiliation: 1 Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Lin
authors.affiliation: 1 Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
authors.forename: Edward K
authors.initials: EK
authors.lastname: Avila
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D003422:Critical Care / Q000379:methods; D006801:Humans; D007427:Intracranial Pressure; D008279:Magnetic Resonance Imaging; D009369:Neoplasms / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D009422:Nervous System Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D000072078:Positron Emission Tomography Computed Tomography; D017410:Practice Guidelines as Topic; D013117:Spinal Cord Compression / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013226:Status Epilepticus / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D020521:Stroke / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents
keywords: cord compression; elevated intracranial pressure; neuro-oncology; status epilepticus; stroke