title: New modes in non-invasive ventilation.
abstract: Non-invasive ventilation is useful to treat some forms of respiratory failure. Hence, the number of patients receiving this treatment is steadily increasing. Considerable conceptual and technical progress has been made in the last years by manufacturers concerning this technique. This includes new features committed to improve its effectiveness as well as patient-ventilator interactions. The goal of this review is to deal with latest advances in ventilatory modes and features available for non-invasive ventilation. We present a comprehensive analysis of new modes of ventilator assistance committed to treat respiratory failure (hybrid modes) and central and complex sleep apnea (adaptive servo ventilation), and of new modes of triggering and cycling (neurally adjusted ventilatory assist). Technical aspects, modes of operation and settings of these new features as well as an exhaustive review of published data, their benefits and limits, and the potential place of these devices in clinical practice, are discussed.
authors.affiliation: Pulmonary Departement and Respiratory Critical Care Unit, University Hospital Dijon, France; Inserm U 866, University of Burgundy, School of Medicine, Dijon, France. Electronic address: claudio.rabec@chu-dijon.fr.
authors.forename: Claudio
authors.initials: C
authors.lastname: Rabec
authors.affiliation: Pediatric Intensive Care Unit, Saint Justine Hospital, Université de Montréal, Montreal, Canada.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Emeriaud
authors.affiliation: AP-HP, Hôpital Necker, Pediatric Noninvasive Ventilation and Sleep Unit, Paris, France; Paris Descartes University, France; Inserm U 955, Team 13, Créteil, France.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Amadeo
authors.affiliation: AP-HP, Hôpital Necker, Pediatric Noninvasive Ventilation and Sleep Unit, Paris, France; Paris Descartes University, France; Inserm U 955, Team 13, Créteil, France.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Fauroux
authors.affiliation: Pulmonary Departement and Respiratory Critical Care Unit, University Hospital Dijon, France; Inserm U 866, University of Burgundy, School of Medicine, Dijon, France.
authors.forename: Marjolaine
authors.initials: M
authors.lastname: Georges
mesh_terms: D006801:Humans; D063087:Noninvasive Ventilation / Q000379:methods*; D012131:Respiratory Insufficiency / Q000628:therapy*
keywords: Adaptative Servo Ventilation; Central sleep apnea; Neuro Adjusted Ventilatory Assist; Non invasive ventilation; Respiratory failure; Ventilatory modes