title: ROPtool analysis of images acquired using a noncontact handheld fundus camera (Pictor)--a pilot study.
abstract: The presence of plus disease is the primary indication for treatment of retinopathy of prematurity (ROP), but its diagnosis is subjective and prone to error. ROPtool is a semiautomated computer program that quantifies vascular tortuosity and dilation. Pictor is an FDA-approved, noncontact, handheld digital fundus camera. This pilot study evaluated ROPtool's ability to analyze high-quality Pictor images of premature infants and its accuracy in diagnosing plus disease compared to clinical examination. In our small sample of images, ROPtool could trace and identify the presence of plus disease with high accuracy.
authors.affiliation: Duke University Eye Center, Durham, North Carolina.
authors.forename: Laura A
authors.initials: LA
authors.lastname: Vickers
authors.affiliation: Duke University Eye Center, Durham, North Carolina.
authors.forename: Sharon F
authors.initials: SF
authors.lastname: Freedman
authors.affiliation: Duke University Eye Center, Durham, North Carolina.
authors.forename: David K
authors.initials: DK
authors.lastname: Wallace
authors.affiliation: Duke University Eye Center, Durham, North Carolina. Electronic address: Grace.Prakalapakorn@duke.edu.
authors.forename: S Grace
authors.initials: SG
authors.lastname: Prakalapakorn
mesh_terms: D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007223:Infant; D007231:Infant, Newborn; D009887:Ophthalmoscopy; D010781:Photography / Q000295:instrumentation*; D010808:Physical Examination; D010865:Pilot Projects; D012372:ROC Curve; D015203:Reproducibility of Results; D012171:Retinal Vessels / Q000473:pathology*; D012178:Retinopathy of Prematurity / Q000175:diagnosis*; D012680:Sensitivity and Specificity