title: Synthesis and Utility of Dihydropyridine Boronic Esters.
abstract: When activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine products.
authors.affiliation: Department of Biochemistry, Division of Chemistry, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-0938, USA.
authors.forename: Santanu
authors.initials: S
authors.lastname: Panda
authors.affiliation: Department of Biochemistry, Division of Chemistry, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-0938, USA.
authors.forename: Aaron
authors.initials: A
authors.lastname: Coffin
authors.affiliation: Department of Chemistry, UC Davis, One Shields Ave, Davis, CA, 95616, USA.
authors.forename: Q Nhu
authors.initials: QN
authors.lastname: Nguyen
authors.affiliation: Department of Chemistry, UC Davis, One Shields Ave, Davis, CA, 95616, USA.
authors.forename: Dean J
authors.initials: DJ
authors.lastname: Tantillo
authors.affiliation: Department of Biochemistry, Division of Chemistry, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-0938, USA. joseph.ready@utsouthwestern.edu.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Ready
mesh_terms: D001897:Boronic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D004095:Dihydropyridines / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011789:Quantum Theory
chemical_list: D001897:Boronic Acids; D004095:Dihydropyridines; D004952:Esters; C038806:1,4-dihydropyridine
keywords: allylic compounds; boron; heterocycles; samarium iodide; synthetic methods