title: Evaluation of hepatic antioxidant changes in ovine dicrocoeliosis.
abstract: Dicrocoeliosis, caused by Dicrocoelium dendriticum is a hepatic parasitic disease of clinical and financial significance in ruminant breeding, which causes direct losses due to condemnation of parasitized livers. The purpose of our study was to assess the effects of natural dicrocoeliosis on the antioxidant defence capability of the liver in sheep. For this purpose, livers of 40 infected sheep with D. dendriticum along with livers of 20 healthy (control) sheep were collected from animals slaughtered in Khuzestan province, Iran. An increase in malondialdehyde concentrations accompanied by decreased activities of SOD and GPX of infected liver was noticed when compared with control values. Our data indicate that through dicrocoeliosis insufficient scavenging of reactive oxygen species takes place and caused oxidative liver damage.
authors.affiliation: Department of Parasitology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
authors.forename: Somayeh
authors.initials: S
authors.lastname: Bahrami
authors.affiliation: Department of Parasitology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
authors.forename: Mohamad Hossein
authors.initials: MH
authors.lastname: Razi Jalali
authors.affiliation: Department of Parasitology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
authors.forename: Arash
authors.initials: A
authors.lastname: Jafari
keywords: Antioxidant enzyme; Dicrocoelium dendriticum; Lipid peroxidation; Liver