title: One-pot tandem Ugi-4CR/S(N)Ar approach to highly functionalized quino[2,3-b][1,5]benzoxazepines.
abstract: We have developed a convenient and facile method for the synthesis of functionalized diverse quino[2,3-b][1,5]benzoxazepines. These new compounds were synthesized through a one-pot sequential Ugi-4CR/base-free intramolecular aromatic nucleophilic substitution (S(N)Ar) reaction in moderate to good yields from readily available starting materials. Structural confirmation of the products is confirmed by analytical data and X-ray crystallography.
authors.affiliation: School of Chemistry, College of Science, University of Tehran, P.O. Box 14155 6455, Tehran, Iran. ghandi@khayam.ut.ac.ir.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Ghandi
authors.affiliation: School of Chemistry, College of Science, University of Tehran, P.O. Box 14155 6455, Tehran, Iran.
authors.forename: Nahid
authors.initials: N
authors.lastname: Zarezadeh
authors.affiliation: School of Chemistry, College of Science, University of Tehran, P.O. Box 14155 6455, Tehran, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Abbasi
mesh_terms: D048588:Benzoxazines / Q000138:chemical synthesis* / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D011809:Quinones / Q000737:chemistry*
chemical_list: D048588:Benzoxazines; D011809:Quinones
keywords: 2-Chloroquinoline-3-carbaldehyde; MCRs; Quino[2, 3-b][1, 5]benzoxazepine; Ugi reaction; reaction