title: Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking.
abstract: A novel dual marking hydrogel system is reported for radiological and laparoscopic localization of lesions. Bioorthogonally crosslinked hydrogel containing both tantalum and India ink can be rapidly formed inside the body after injecting precursors, and stably located for several days as a long-term biocompatible carrier for markers.
authors.affiliation: Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
authors.forename: Seonki
authors.initials: S
authors.lastname: Hong
authors.affiliation: Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Carlson
authors.affiliation: Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
authors.forename: Hakho
authors.initials: H
authors.lastname: Lee
authors.affiliation: Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.|Department of Systems Biology, Harvard Medical School, Boston, MA, 02114, USA.
authors.forename: Ralph
authors.initials: R
authors.lastname: Weissleder
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D004724:Endoscopy / Q000379:methods*; D057918:Fiducial Markers; D020100:Hydrogels / Q000737:chemistry*; D007281:Ink; D010535:Laparoscopy / Q000379:methods; D051379:Mice; D041681:NIH 3T3 Cells; D011871:Radiology / Q000379:methods
chemical_list: D001672:Biocompatible Materials; D020100:Hydrogels
keywords: bioorthogonal radiopaque hydrogels; endoscopic delivery; hybrid materials; hydrogels; medical applications