title: Antimicrobial Activity of the Essential Oil from the Leaves and Seeds ofCoriandrum sativumtoward Food-borne Pathogens.
abstract: The increasing incidence of drug-resistant pathogens and toxicity of existing antibacterial compounds has drawn attention toward the antimicrobial activity of natural products. The purpose of this study is to evaluate the antimicrobial activity of the essential oil of the leaves and seeds ofCoriandrum sativum. The five strains of bacteria comprisingEscherichia coli, Staphylococcus aureus, Yersinia enterocolitica, Salmonella entericaandVibrio choleraewere used for the antibacterial tests. In this study, antimicrobial effects of the essential oil from the leaves and seeds ofCoriandrum sativumare evaluated by determining the minimum inhibitory concentration (MIC), the inhibition zone and minimum bactericidal concentration (MBC). The essential oil fromCoriandrum sativumwas extracted by steam distillation. The results indicate that the antimicrobial activities against the five pathogens were in the range of 2.5- 320 µg/mL. Increase in essential oil concentration caused significant increase in inhibitory feature. The essential oil of the leaves and seeds ofCoriandrum sativumshowed antimicrobial activity against the food-borne pathogenic bacteria. Thus, its oil can be used as an alternative to synthetic food preservative without toxic effects. Also, it can be used in biotechnological fields as ingredients in antibiotics and the pharmaceutical industry. These results suggest that the essential oil ofC sativumleaves and seeds may have potential use in pharmaceutical and food industries for preservatives or antimicrobial agents.
authors.affiliation: Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences (TUMS), Tehran, Iran.|Department of Biology, Payame Noor University, Tehran, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Rezaei
authors.affiliation: Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
authors.forename: F
authors.initials: F
authors.lastname: Karimi
authors.affiliation: Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences (TUMS), Tehran, Iran. E-mail: Nshariatifar@ut.ac.ir.
authors.forename: N
authors.initials: N
authors.lastname: Shariatifar
authors.affiliation: Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
authors.forename: I
authors.initials: I
authors.lastname: Mohammadpourfard
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Tehran, Iran. Tehran University of Medical Sciences (TUMS), Tehran, Iran.
authors.forename: E
authors.initials: E
authors.lastname: Shiri Malekabad
keywords: Coriandrum sativum; essential oil; food safety; food-borne pathogen