title: A novel colorimetric and fluorescent iminocoumarin-based chemosensor for acetate ion and its application to living cell imaging.
abstract: A novel colorimetric and fluorescent iminocoumarin-based turn-off chemosensor for acetate ion was designed and synthesized. The chemosensor could fast detect acetate ion in a 1:1 ratio within 150 ms, which could not be affected by various coexisting anions, even F(-). Futher studies showed that the detect limit was as low as 2.05×10(-7) M, and the binding constant was determined to be 1.02×10(8) M(-1). Due to these unique properties, the chemosensor showed potential application in intracellular imaging.
authors.affiliation: College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, PR China. Electronic address: jiangyi@iccas.ac.cn.
authors.forename: Yi
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, PR China.
authors.forename: Lei-Li
authors.initials: LL
authors.lastname: Sun
authors.affiliation: College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, PR China.
authors.forename: Guang-Zong
authors.initials: GZ
authors.lastname: Ren
authors.affiliation: College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, PR China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Niu
authors.affiliation: College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, PR China. Electronic address: huzhiqiang@iccas.ac.cn.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Hu
mesh_terms: D000085:Acetates / Q000032:analysis*; D002470:Cell Survival; D003124:Colorimetry / Q000379:methods*; D004926:Escherichia coli / Q000166:cytology; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D042541:Intracellular Space / Q000378:metabolism; D057054:Molecular Imaging / Q000379:methods*; D012235:Rhodamines / Q000737:chemistry*
chemical_list: D000085:Acetates; D005456:Fluorescent Dyes; D012235:Rhodamines
keywords: Acetate ion; Iminocoumarin-based chemosensor; Intracellular imaging; Selectively; Sensitively