title: [Clinicopathologic study of 25 cases of placental chorioangioma].
abstract: OBJECTIVE
  To investigate the clinicopathological characteristics, diagnostic criteria and differential diagnosis of placental chorioangioma.
  
  
  METHODS
  Twenty-five cases of placental chorioangioma were analyzed for their clinical data, histomorphology and immumohisto chemical staining. Relevant literature was reviewed.
  
  
  RESULTS
  The average age of the 25 patients was 29 years. Fourteen patients had full-term pregnancy, 10 had preterm labor, and 1 had intrauterine fetal death. Nineteen patients had pregnancy complications. The tumors presented as red or dusty pink nodules with clear borders. The tumor size ranged from 1 to 16 cm. Microscopically, the tumors possessed abundant capillaries or cavernous blood spaces lined by hyperplastic endothelial cells. These cells were positive for CD34 and Ki-67 index < 10%.
  
  
  CONCLUSIONS
  Placental chorioangioma is a rare benign tumor of the placenta, and is associated with various pregnancy complications. Misdiagnosis of cell-rich type tumor should be avoided.
authors.affiliation: Department of Pathology, Haidian Maternal and Child Health Hoipital, Beijing 100080, China.
authors.forename: Aichun
authors.initials: A
authors.lastname: Wang
authors.forename: Yaqi
authors.initials: Y
authors.lastname: Ma
authors.forename: Yun
authors.initials: Y
authors.lastname: Wang
authors.forename: Yingnan
authors.initials: Y
authors.lastname: Wang
authors.forename: Junling
authors.initials: J
authors.lastname: Xie
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Yuan
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Gu
authors.affiliation: Department of Pathology, People's Liberation Army General Hospital, Beijing 100853, China; E-mail: aliu301@126.com.
authors.forename: Aijun
authors.initials: A
authors.lastname: Liu
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D042783:Endothelial Cells / Q000473:pathology; D005260:Female; D005313:Fetal Death; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D010920:Placenta / Q000473:pathology; D010922:Placenta Diseases / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*; D050497:Stillbirth