title: Recent advances in the dark adaptation investigations.
abstract: Dark adaptation is a highly sensitive neural function and may be the first symptom of many status including the physiologic and pathologic entity, suggesting that it could be instrumental for diagnose. However, shortcomings such as the lack of standardized parameters, the long duration of examination, and subjective randomness would substantially impede the use of dark adaptation in clinical work. In this review we summarize the recent research about the dark adaptation, including two visual cycles-canonical and cone-specific visual cycle, affecting factors and the methods for measuring dark adaptation. In the opinions of authors, intensive investigations are needed to be done for the widely use of this significant visual function in clinic.
authors.affiliation: Department of Clinical Aerospace Medicine, the Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China.
authors.forename: Guo-Qing
authors.initials: GQ
authors.lastname: Yang
authors.affiliation: Department of Clinical Aerospace Medicine, the Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, Beidaihe Hospital of PLA, Beidaihe 066100, Hebei Province, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Tao
authors.affiliation: Department of Clinical Aerospace Medicine, the Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China.
authors.forename: Zuo-Ming
authors.initials: ZM
authors.lastname: Zhang
keywords: adaptometer; dark adaptation; pigment regeneration; visual cycle