title: Microrobotized blasting improves the bone-to-textured implant response. A preclinical in vivo biomechanical study.
abstract: This study evaluated the effect of microrobotized blasting of titanium endosteal implants relative to their manually blasted counterparts. Two different implant systems were utilized presenting two different implant surfaces. Control surfaces (Manual) were fabricated by manually grit blasting the implant surfaces while experimental surfaces (Microblasted) were fabricated through a microrobotized system that provided a one pass grit blasting routine. Both surfaces were created with the same ~50µm average particle size alumina powder at ~310KPa. Surfaces were then etched with 37% HCl for 20min, washed, and packaged through standard industry procedures. The surfaces were characterized through scanning electron microscopy (SEM) and optical interferometry, and were then placed in a beagle dog radius model remaining in vivo for 3 and 6 weeks. The implant removal torque was recorded and statistical analysis evaluated implant system and surface type torque levels as a function of time in vivo. Histologic sections were qualitatively evaluated for tissue response. Electron microscopy depicted textured surfaces for both manual and microblasted surfaces. Optical interferometry showed significantly higher Sa, Sq, values for the microblasted surface and no significant difference for Sds and Sdr values between surfaces. In vivo results depicted that statistically significant gains in biomechanical fixation were obtained for both implant systems tested at 6 weeks in vivo, while only one system presented significant biomechanical gain at 3 weeks. Histologic sections showed qualitative higher amounts of new bone forming around microblasted implants relative to the manually blasted group. Microrobotized blasting resulted in higher biomechanical fixation of endosteal dental implants and should be considered as an alternative for impant surface manufacturing.
authors.affiliation: Department of Biomaterials and Biomimetics, New York University, 433 1st Ave., Room 844, New York, NY 10010, USA; Director for Research, Department of Periodontology and Implant Dentistry, New York University College of Dentistry, 345E 24th Street, New York, NY 10010, USA; Affiliated Faculty, Department of Engineering, New York University Abu Dhabi, PO Box 129188, Abu Dhabi, United Arab Emirates.
authors.forename: Paulo G
authors.initials: PG
authors.lastname: Coelho
authors.affiliation: Department of Dentistry, Division of Oral and Maxillofacial Surgery, Universidade Federal de Santa Catarina, R. Eng. Agronômico Andrei Cristian Ferreira, s/n-Trindade, Florianópolis, SC 88040-900, Brazil.
authors.forename: Luiz F
authors.initials: LF
authors.lastname: Gil
authors.affiliation: Department of Periodontology, University of Florida at Gainesville, 1395 Center Dr, Gainesville, FL 32610, USA.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Neiva
authors.affiliation: Department of Prosthodontics, Malmo University, Malmo 205 06, Sweden.
authors.forename: Ryo
authors.initials: R
authors.lastname: Jimbo
authors.affiliation: Department of Biomaterials and Biomimetics, New York University, 433 1st Ave., Room 844, New York, NY 10010, USA.
authors.forename: Nick
authors.initials: N
authors.lastname: Tovar
authors.affiliation: École Nationale Vétérinaire d׳Alfort, 7 Avenue du Général de Gaulle, 94704 Mainsons-Alfort, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Lilin
authors.affiliation: Department of Prosthodontics, University of Sao Paulo - Bauru College of Dentistry, Alameda Otávio Pinheiro Brisola 9-75, Bauru, SP 17.012-901, Brazil. Electronic address: estevamab@gmail.com.
authors.forename: Estevam A
authors.initials: EA
authors.lastname: Bonfante
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001842:Bone and Bones / Q000187:drug effects / Q000502:physiology; D004285:Dogs; D008297:Male; D055595:Mechanical Phenomena; D055616:Microtechnology / Q000295:instrumentation*; D016348:Osseointegration / Q000187:drug effects; D011312:Pressure; D019736:Prostheses and Implants; D012371:Robotics; D013499:Surface Properties; D014025:Titanium / Q000494:pharmacology
chemical_list: D014025:Titanium
keywords: Bone; Healing chamber; Histology; Implant; Mechanical; Surface