title: Developmental patterns of copper bioaccumulation in a marine fish model Oryzias melastigma.
abstract: Allometry is known to be an important factor influencing metal bioaccumulation in animals. However, it is not clear whether effects are due to body size per se or changes in physiological traits during the animals' development. We therefore investigated the biokinetics of copper (Cu) and predicted Cu bioaccumulation during the development of a fish model, the marine medaka. The results revealed that the waterborne Cu uptake rate constant decreased and dietary Cu assimilation efficiency increased during development from larvae to adults. Thus, the allometric dependency of the biokinetic parameters in juveniles and adults can not be simply extrapolated to the whole life cycle. The body Cu concentration in the fish was predicted by the biokinetic model, which showed a rapid increase in the larval stage, followed by a slight increase from juveniles to adults, and then a relatively stable plateau in the post-adult stage. Dietary Cu uptake became more important as fish developed from larvae to juveniles, but became less important from juveniles to adults. These findings suggested that the developmental patterns of metal bioaccumulation are driven by an integrated biological/physiological shift through animals' ontogeny rather than a simple allometric dependent change. The developmental changes of metal uptake should be considered in ecological bioassessment and biomonitoring programs.
authors.affiliation: Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, Chinese Academy of Sciences, South China Sea Institute of Oceanology, Guangzhou 510301, China; Department of Life and Environmental Sciences, Faculty of Science and Technology, Bournemouth University, Fern Barrow, Poole, Dorset, BH12 5BB, UK.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Guo
authors.affiliation: Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, Chinese Academy of Sciences, South China Sea Institute of Oceanology, Guangzhou 510301, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, Chinese Academy of Sciences, South China Sea Institute of Oceanology, Guangzhou 510301, China.
authors.forename: Sen
authors.initials: S
authors.lastname: Du
authors.affiliation: Department of Life and Environmental Sciences, Faculty of Science and Technology, Bournemouth University, Fern Barrow, Poole, Dorset, BH12 5BB, UK.
authors.forename: Iain
authors.initials: I
authors.lastname: Green
authors.affiliation: Key Laboratory of the Coastal and Wetland Ecosystems, Ministry of Education, College of Environment and Ecology, Xiamen University, Xiamen, Fujian 361102, China.
authors.forename: Qiaoguo
authors.initials: Q
authors.lastname: Tan
authors.affiliation: Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, Chinese Academy of Sciences, South China Sea Institute of Oceanology, Guangzhou 510301, China. Electronic address: zhangli@scsio.ac.cn.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000378:metabolism*; D003300:Copper / Q000378:metabolism*; D004784:Environmental Monitoring; D005260:Female; D007700:Kinetics; D008297:Male; D023421:Models, Animal; D009990:Oryzias / Q000254:growth & development* / Q000378:metabolism*; D012044:Regression Analysis; D014874:Water Pollutants, Chemical / Q000633:toxicity
chemical_list: D014874:Water Pollutants, Chemical; D003300:Copper
keywords: Biokinetic model; Copper; Fish; Metal uptake; Ontogenetic development