title: Biliary tract cancer registry in Japan from 2008 to 2013.
abstract: BACKGROUND
  The present study analyzed biliary tract cancer patients registered from 2008 to 2013 in Japan and evaluated the outcomes of biliary tract cancer.
  
  
  METHODS
  A total of 18,606 patients were registered from 2008 to 2013. Cases were analyzed with regard to patient survival according to contiguous extent of the primary tumor (T), node metastasis, and tumor stage using the 3rd English edition of the Japanese classification of the biliary tract cancers.
  
  
  RESULTS
  Five-year survival rates were 39.8% for gallbladder cancer, 24.2% for perihilar bile duct cancer, 39.1% for distal bile duct cancer, and 61.3% for ampullary region cancer. Significant differences were observed between newly introduced subdivisions in the new Japanese classification for all tumoral sites except gallbladder cancer. The survival rate in patients with #13a metastasis was significantly higher than in patients with distant lymph node metastasis.
  
  
  CONCLUSIONS
  The new Japanese classification adopted the 7th edition of staging system developed by the Union for International Cancer Control staging system. However, numerous aspects of these classification systems remain unvalidated. The present analysis demonstrated the significance of a proportion of T factor subdivisions and classifications of regional lymph nodes in cases of gallbladder cancer in the new Japanese classification.
authors.affiliation: Department of General Surgery and Pancreatic Surgery, Fujita Health University, 1-98 Dengakygakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Ishihara
authors.affiliation: Department of General Surgery and Pancreatic Surgery, Fujita Health University, 1-98 Dengakygakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan. akihori@fujita-hu.ac.jp.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Horiguchi
authors.affiliation: Toyota Regional Medical Center, Toyota, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Miyakawa
authors.affiliation: Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
authors.forename: Itaru
authors.initials: I
authors.lastname: Endo
authors.affiliation: Department of General Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Miyazaki
authors.affiliation: Department of Surgery, Teikyo University, Tokyo, Japan.
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Takada
mesh_terms: D001661:Biliary Tract Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D012042:Registries; D015996:Survival Rate
keywords: Biliary tract cancers; Japanese classification; Lymph node metastasis; Stage of disease; UICC staging system