title: C-Reactive Protein Concentrations and Level of Physical Activity in Men and Women With Normal and Impaired Glucose Tolerance. A Cross-Sectional Population-Based Study in Sweden.
abstract: We aimed to explore the association between self-reported leisure time physical activity (LTPA) and C-reactive protein (CRP) concentrations in men and women with and without impaired glucose tolerance (IGT).
  
  
  
  In a cross-sectional study, a random sample (n = 2,816) was examined with an oral glucose tolerance test, CRP and information about LTPA. Those with IGT or normal glucose tolerance (NGT) and CRP value ≤10 mg/L were selected (n = 2,367) for the study.
  
  
  
  An inverse association between LTPA and CRP concentrations was observed in the population (P < .001), though, only in men with IGT (P = .023) and in women with NGT. Men with IGT, reporting slight physical activity up to 4 hours a week presented significantly higher CRP concentrations than normoglycemic men (Δ0.6 mg/L, P = .004). However, this difference could not be found in men with IGT reporting more intense physical activity (Δ0.01 mg/L, P = .944).
  
  
  
  Physical inactivity seems to have greater inflammatory consequences for men (vs. women) with IGT. More importantly, although 4 hours of physical activity per week is more than the usual minimum recommendation, an even greater intensity of LTPA appears to be required to limit subclinical inflammation in men with IGT.
authors.affiliation: Dept of Primary Health Care, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Margareta I
authors.initials: MI
authors.lastname: Hellgren
authors.forename: Charlotte A
authors.initials: CA
authors.lastname: Larsson
authors.forename: Bledar
authors.initials: B
authors.lastname: Daka
authors.forename: Max
authors.initials: M
authors.lastname: Petzold
authors.forename: Per-Anders
authors.initials: PA
authors.lastname: Jansson
authors.forename: Ulf
authors.initials: U
authors.lastname: Lindblad
mesh_terms: D000328:Adult; D000368:Aged; D002097:C-Reactive Protein / Q000378:metabolism*; D003430:Cross-Sectional Studies; D015444:Exercise / Q000502:physiology*; D005260:Female; D018149:Glucose Intolerance / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D002097:C-Reactive Protein