title: Anterior temporal lobectomy versus selective amygdalohippocampectomy in patients with mesial temporal lobe epilepsy.
abstract: OBJECTIVE
  To contribute our experience with surgical treatment of patients with mesial temporal lobe epilepsy (mTLE) undergoing anterior temporal lobectomy (ATL) or selective amygdalohippocampectomy (SelAH).
  
  
  METHODS
  This is a retrospective observational study. The sample included patients with medically refractory mTLE due to unilateral mesial temporal sclerosis who underwent either ATL or SelAH, at Hospital de Clinicas - UFPR, from 2005 to 2012. We report seizure outcomes, using Engel classification, cognitive outcomes, using measurements of verbal and visuospatial memories, as well as operative complications.
  
  
  RESULTS
  Sixty-seven patients (33 ATL, 34 SelAH) were studied; median follow-up was 64 months. There was no statistically significant difference in seizure or neuropsychological outcomes, although verbal memory was more negatively affected in ATL operations on patients' dominant hemispheres. Higher number of major complications was observed in the ATL group (p = 0.004).
  
  
  CONCLUSIONS
  Seizure and neuropsychological outcomes did not differ. ATL appeared to be associated with higher risk of complications.
authors.affiliation: Division of Neurology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Fábio A
authors.initials: FA
authors.lastname: Nascimento
authors.affiliation: Departamento de Neurocirurgia, Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Luana Antunes Maranha
authors.initials: LA
authors.lastname: Gatto
authors.affiliation: Departamento de Neurologia, Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Carlos
authors.initials: C
authors.lastname: Silvado
authors.affiliation: Departamento de Neurologia, Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Maria Joana
authors.initials: MJ
authors.lastname: Mäder-Joaquim
authors.affiliation: Departamento de Neurocirurgia, Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Marlus Sidney
authors.initials: MS
authors.lastname: Moro
authors.affiliation: Departamento de Neurocirurgia, Hospital de Clinicas, Universidade Federal do Paraná, Curitiba, PR, Brazil.
authors.forename: Joao Candido
authors.initials: JC
authors.lastname: Araujo
mesh_terms: D000328:Adult; D000679:Amygdala / Q000601:surgery*; D038481:Anterior Temporal Lobectomy / Q000009:adverse effects / Q000379:methods*; D000069279:Drug Resistant Epilepsy / Q000601:surgery; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006624:Hippocampus / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012640:Seizures / Q000453:epidemiology / Q000517:prevention & control; D016896:Treatment Outcome