title: A palladium-catalyzed coupling reaction of aryl nonaflates, sulfur dioxide, and hydrazines.
abstract: A facile route to synthesise N-aminosulfonamides through a palladium-catalyzed coupling reaction of aryl nonaflates, sulfur dioxide, and hydrazines is reported. This transformation proceeds in the presence of Pd(OAc)2/XantPhos, and TBAB in 1,4-dioxane at 80 °C, leading to the corresponding N-aminosulfonamides in moderate to good yields. The reaction scope has been demonstrated, and good functional tolerance is observed. A plausible mechanism is proposed through the insertion of sulfur dioxide.
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China. jie_wu@fudan.edu.cn.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: An
authors.affiliation: Department of Biochemistry and Molecular Biology, Zhejiang University School of Medicine, Hangzhou 310058, China. hongguangxia@zju.edu.cn.
authors.forename: Hongguang
authors.initials: H
authors.lastname: Xia
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China. jie_wu@fudan.edu.cn and State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Wu