title: Bilateral isolated lens coloboma associated with bicuspid aortic valve.
abstract: A 27-year-old woman presented with a history of long-standing poor vision in both eyes. Ophthalmologic examination after pupillary dilatation revealed bilateral lens coloboma situated in the inferotemporal quadrant. No associated ocular abnormalities were seen, except amblyopia. A bicuspid aortic valve was observed during echocardiography during systemic evaluation. Lens coloboma usually occurs unilaterally; however, bilateral lens coloboma which is isolated or associated with other ocular malformations is also encountered. This is the first description of bilateral isolated lenticular coloboma associated with bicuspid aortic valve. Although the association between bicuspid aortic valve and lens coloboma may be an incidental finding, they may be components of an unknown syndrome.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Dogan
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Onur
authors.initials: O
authors.lastname: Polat
authors.affiliation: Department of Cardiology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Onder
authors.initials: O
authors.lastname: Akcı
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Guliz Fatma
authors.initials: GF
authors.lastname: Yavas
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Umit Ubeyt
authors.initials: UU
authors.lastname: Inan
mesh_terms: D000328:Adult; D001021:Aortic Valve / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000503:physiopathology; D000082882:Bicuspid Aortic Valve Disease; D003103:Coloboma / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007908:Lens, Crystalline; D013577:Syndrome; D014463:Ultrasonography; D014792:Visual Acuity