title: Getting Tumor Dendritic Cells to Engage the Dead.
abstract: The immunogenic effects of chemotherapy rely on effective activation of dendritic cells to present antigen to tumor-specific T cells. However, the signals that govern how dendritic cells seek out dying cancer cells to initiate this process are poorly understood. A recent study by Vacchelli et al. provides important insight.
authors.affiliation: Abramson Family Cancer Research Institute, Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Lisa
authors.initials: L
authors.lastname: Cucolo
authors.affiliation: Abramson Family Cancer Research Institute, Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: andyminn@mail.med.upenn.edu.
authors.forename: Andy J
authors.initials: AJ
authors.lastname: Minn
mesh_terms: D000818:Animals; D018943:Anthracyclines / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000276:immunology*; D044042:Receptors, Formyl Peptide / Q000502:physiology*
chemical_list: D018943:Anthracyclines; D044042:Receptors, Formyl Peptide