title: A new transmission methodology for quality assurance in radiotherapy based on radiochromic film measurements.
abstract: Despite individual quality assurance (QA) being recommended for complex techniques in radiotherapy (RT) treatment, the possibility of errors in dose delivery during therapeutic application has been verified. Therefore, it is fundamentally important to conduct in vivo QA during treatment. This work presents an in vivo transmission quality control methodology, using radiochromic film (RCF) coupled to the linear accelerator (linac) accessory holder. This QA methodology compares the dose distribution measured by the film in the linac accessory holder with the dose distribution expected by the treatment planning software. The calculated dose distribution is obtained in the coronal and central plane of a phantom with the same dimensions of the acrylic support used for positioning the film but in a source-to-detector distance (SDD) of 100 cm, as a result of transferring the IMRT plan in question with all the fields positioned with the gantry vertically, that is, perpendicular to the phantom. To validate this procedure, first of all a Monte Carlo simulation using PENELOPE code was done to evaluate the differences between the dose distributions measured by the film in a SDD of 56.8 cm and 100 cm. After that, several simple dose distribution tests were evaluated using the proposed methodology, and finally a study using IMRT treatments was done. In the Monte Carlo simulation, the mean percentage of points approved in the gamma function comparing the dose distribution acquired in the two SDDs were 99.92% ± 0.14%. In the simple dose distribution tests, the mean percentage of points approved in the gamma function were 99.85% ± 0.26% and the mean percentage differences in the normalization point doses were -1.41%. The transmission methodology was approved in 24 of 25 IMRT test irradiations. Based on these results, it can be concluded that the proposed methodology using RCFs can be applied for in vivo QA in RT treatments.
authors.affiliation: Sciences and Letters of Ribeirão Preto University of São Paulo. leonardo.fis@hotmail.com.
authors.forename: Leonardo L
authors.initials: LL
authors.lastname: do Amaral
authors.forename: Harley F
authors.initials: HF
authors.lastname: de Oliveira
authors.forename: Juliana F
authors.initials: JF
authors.lastname: Pavoni
authors.forename: Franciso
authors.initials: F
authors.lastname: Sampaio
authors.forename: Thomaz
authors.initials: T
authors.lastname: Ghillardi Netto
mesh_terms: D000465:Algorithms; D005373:Film Dosimetry / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D009010:Monte Carlo Method; D009369:Neoplasms / Q000532:radiotherapy*; D019047:Phantoms, Imaging; D011785:Quality Assurance, Health Care / Q000379:methods / Q000592:standards*; D011786:Quality Control; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000592:standards*; D050397:Radiotherapy, Intensity-Modulated / Q000592:standards*; D012984:Software