title: Physical Comorbidities in Depression Co-Occurring with Anxiety: A Cross Sectional Study in the Czech Primary Care System.
abstract: Comorbidities associated with depression have been researched in a number of contexts. However, the epidemiological situation in clinical practice is understudied, especially in the post-Communist Central and Eastern Europe region. The aim of this study was to assess physical comorbidities in depression, and to identify whether there are increased odds of physical comorbidities associated with co-occurring depressive and anxiety disorders. Data on 4264 patients aged 18-98 were collected among medical doctors in the Czech Republic between 2010 and 2011. Descriptive statistics were calculated and multiple logistic regressions were performed to assess comorbidities among patients with depressive disorder. There were 51.29% of those who have a physical comorbidity, and 45.5% of those who have a comorbid anxiety disorders among patients treated with depression in Czech primary care. Results of logistic regressions show that odds of having pain, hypertension or diabetes mellitus are particularly elevated at those who have co-occurring depressive and anxiety disorder. Our findings demonstrate that comorbidities associated with depressive disorders are highly prevalent in primary health care practice, and that physical comorbidities are particularly frequent among those with co-occurring depressive and anxiety disorders.
authors.affiliation: National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic. petr.winkler@nudz.cz.|Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, London SE5 8AF, UK. petr.winkler@nudz.cz.
authors.forename: Petr
authors.initials: P
authors.lastname: Winkler
authors.affiliation: National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic. jiri.horacek@nudz.cz.|Third Medical Faculty, Charles University, Ruská 2411/87, 100 00 Prague, Czech Republic. jiri.horacek@nudz.cz.
authors.forename: Jiří
authors.initials: J
authors.lastname: Horáček
authors.affiliation: National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic. aneta.weissova@nudz.cz.
authors.forename: Aneta
authors.initials: A
authors.lastname: Weissová
authors.affiliation: KRKA Čr, S.r.o, Mezibranská 579/7, 110 00 Prague, Czech Republic. martin.sustr@kzka.biz.
authors.forename: Martin
authors.initials: M
authors.lastname: Šustr
authors.affiliation: National Institute of Mental Health, Topolová 748, 250 67 Klecany, Czech Republic. martin.brunovsky@nudz.cz.|Third Medical Faculty, Charles University, Ruská 2411/87, 100 00 Prague, Czech Republic. martin.brunovsky@nudz.cz.
authors.forename: Martin
authors.initials: M
authors.lastname: Brunovský
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001008:Anxiety Disorders / Q000453:epidemiology*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D018153:Czech Republic / Q000453:epidemiology; D003866:Depressive Disorder / Q000453:epidemiology*; D005006:Ethnicity / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D018570:Risk Assessment; D055815:Young Adult
keywords: Czech Republic; anxiety; comorbidity; cross-sectional study; depression; prevalence; primary care