title: Protocol for a systematic review of telephone delivered psychosocial interventions on relapse prevention, adherence to psychiatric medication and health risk behaviours in adults with a psychotic disorder.
abstract: BACKGROUND
  The mental and physical health of individuals with a psychotic illness are typically poor. When adhered to, medication can reduce relapse. However, despite adherence, relapse remains common and functional outcomes often remain compromised. Compliance is also typically low. Cardiovascular-related morbidity and mortality is also elevated, along with several important modifiable health risk behaviours. Access to psychosocial interventions is therefore important, but currently limited. Telephone delivered interventions represent a promising solution, although further clarity is needed. Accordingly, we aim to provide an overview and critical analysis of the current state of evidence for telephone delivered psychosocial interventions targeting key health priorities in adults with a psychotic disorder, including (1) relapse, (2) adherence to psychiatric medication and/or (3) modifiable cardiovascular health risk behaviours.
  
  
  METHODS
  Our methods are informed by published guidelines. The review is registered and any protocol amendments will be tracked. Ten electronic peer-reviewed and four grey literature databases have been identified. Preliminary searches have been conducted for literature on psychosocial telephone interventions targeting relapse, medication adherence and/or health risk behaviours in adults with a psychotic disorder. Articles classified as 'evaluation' will be assessed against standardised criteria and checked by an independent assessor. The searches will be re-run just before final analyses and further studies retrieved for inclusion. A narrative synthesis will be reported, structured around intervention type and content, population characteristics and outcomes. Where possible, 'summary of findings' tables will be generated for each comparison. For the primary outcome of each trial, when data are available, we will calculate a risk ratio and its 95% CI (dichotomous outcomes) and/or effect size according to Cohen's formula (continuous outcomes).
  
  
  BACKGROUND
  No ethical issues are foreseen. Findings will be disseminated widely to clinicians and researchers via journal publication and conference presentation(s).
  
  
  BACKGROUND
  PROSPERO CRD42015025402.
authors.affiliation: School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
authors.forename: Alison K
authors.initials: AK
authors.lastname: Beck
authors.affiliation: School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
authors.forename: Amanda
authors.initials: A
authors.lastname: Baker
authors.affiliation: School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.
authors.forename: Alyna
authors.initials: A
authors.lastname: Turner
authors.affiliation: School of Psychological Sciences, The University of Manchester, Manchester, UK.
authors.forename: Gillian
authors.initials: G
authors.lastname: Haddock
authors.affiliation: School of Psychology, University of Wollongong, Wollongong, New South Wales, Australia.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Kelly
authors.affiliation: School of Psychological Sciences, The University of Manchester, Manchester, UK.
authors.forename: Katherine
authors.initials: K
authors.lastname: Berry
authors.affiliation: School of Psychological Sciences, The University of Manchester, Manchester, UK.
authors.forename: Sandra
authors.initials: S
authors.lastname: Bucci
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002985:Clinical Protocols; D003131:Combined Modality Therapy; D006801:Humans; D055118:Medication Adherence; D011613:Psychotherapy / Q000379:methods*; D011618:Psychotic Disorders / Q000517:prevention & control* / Q000628:therapy; D012008:Recurrence; D012309:Risk-Taking; D055502:Secondary Prevention / Q000379:methods*; D000078202:Systematic Reviews as Topic; D017216:Telemedicine / Q000379:methods*; D013689:Telephone
chemical_list: D014150:Antipsychotic Agents
keywords: cardiovascular risk; medication compliance; psychosocial telephone intervention; psychotic disorder; relapse