title: Factors Affecting Well-being and Socio-occupational Functioning in Schizophrenia Patients Following an Acute Exacerbation: A Hospital Based Observational Study.
abstract: BACKGROUND
  Improving functioning levels are an important goal of treatment in schizophrenia. Most studies have described long-term course and outcome in schizophrenia. However, understanding factors influencing functioning in the immediate recovery period following an acute exacerbation may be of important clinical relevance.
  
  
  OBJECTIVE
  The aim of this study is to assess the factors that influence well-being and socio-occupational functioning following an acute exacerbation in schizophrenia patients.
  
  
  METHODS
  The study included 40 patients during the period from June 2013 to June 2014. The possible effect of gender, duration of illness, duration of untreated psychosis, premorbid adjustment, cognitive impairment, facial affect perception and treatment compliance on well-being, and socio-occupational functioning was examined.
  
  
  RESULTS
  About 45% of the individuals experienced below average well-being. On logistic regression analysis poor compliance with medication and poorer cognitive functioning significantly differentiated the patient group with below average well-being from those with an above average well-being. Male gender, poor premorbid adjustment, poor compliance to treatment, poor cognitive functioning, and greater duration of untreated psychosis were found to be associated with a poorer socio-occupational functioning.
  
  
  CONCLUSIONS
  Clinical interventions focusing on improving cognitive impairment and compliance to treatment could play a role in improving well-being, and socio-occupational functioning in schizophrenia patients following an acute exacerbation.
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Roopa
authors.initials: R
authors.lastname: Gopalakrishnan
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Rishikesh V
authors.initials: RV
authors.lastname: Behere
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: P S V N
authors.initials: PS
authors.lastname: Sharma
keywords: Schizophrenia; socio-occupational functioning; well-being