title: Self-Administered Home Series Fecal "Minitransplants" for Recurrent Clostridium difficile Infection on a Rectal Remnant.
abstract: A fecal microbiota transplant has proved to be an extremely effective method for patients with recurrent infections with Clostridium difficile. We present the case of a 65-year-old female patient with multiple Clostridium difficile infection (CDI) relapses on the rectal remnant, post-colectomy for a CDI-related toxic megacolon. The patient also evidenced associated symptomatic Clostridium difficile vaginal infection. She was successfully treated with serial fecal "minitransplants" (self-administered at home) and metronidazole ovules.
authors.affiliation: Lucian Blaga University; Polisano Clinic, Sibiu, Romania. popadaniel1980@yahoo.com.
authors.forename: Daniel
authors.initials: D
authors.lastname: Popa
authors.affiliation: Department of Gastroenterology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Romania.
authors.forename: Mihaela
authors.initials: M
authors.lastname: Laszlo
authors.affiliation: Department of Gastroenterology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology; 3rd Medical Clinic, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Lidia
authors.initials: L
authors.lastname: Ciobanu
authors.affiliation: Polisano Clinic, Sibiu, Romania.
authors.forename: Elena
authors.initials: E
authors.lastname: Ucenic
authors.affiliation: Lucian Blaga University, Sibiu, Romania.
authors.forename: Manuela
authors.initials: M
authors.lastname: Mihalache
authors.affiliation: Department of Gastroenterology, Prof. Dr. Octavian Fodor Regional Institute of Gastroenterology and Hepatology; 3rd Medical Clinic, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Romania.
authors.forename: Oliviu
authors.initials: O
authors.lastname: Pascu
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage; D016360:Clostridioides difficile / Q000187:drug effects / Q000472:pathogenicity*; D003082:Colectomy / Q000009:adverse effects*; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery*; D000069467:Fecal Microbiota Transplantation / Q000379:methods*; D005260:Female; D006801:Humans; D008532:Megacolon, Toxic / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery*; D008795:Metronidazole / Q000008:administration & dosage; D011351:Proctoscopy; D012008:Recurrence; D012648:Self Care; D016896:Treatment Outcome; D014623:Vaginal Diseases / Q000382:microbiology / Q000628:therapy
chemical_list: D000890:Anti-Infective Agents; D008795:Metronidazole