title: Anterior segment parameters and eyelids in systemic sclerosis.
abstract: To evaluate main numerical parameters of anterior segment and the effects of eyelid skin changes on these parameters in patients with systemic sclerosis (SSc). Thirty-four patients with SSc and 34 healthy individuals were enrolled. Besides full eye examination, anterior segment measurements including anterior chamber depth (ACD), anterior chamber volume, anterior chamber angle width, central corneal thickness, pupil size, corneal volume and keratometry were obtained using a Sirius Scheimpflug/Placido photography-based topography system. Eyelid thickness was evaluated using the scala of the modified Rodnan skin score and the patients were subgrouped with respect to these scores to evaluate the effect of eyelid thickening on the anterior segment parameters. Age and sex distributions of the groups were similar (p > 0.05). SSc patients had steeper and thinner corneas, smaller corneal volumes, narrower, shallower and smaller anterior segments but only the mean ACD value of right eyes was found significantly less than those of the controls (p = 0.047). The mean ACD values of SSc subgroup patients with moderate to severe eyelid thickening (50 %) had lower ACD measurements compared to those of control group. (p = 0.043 for the right eyes, p = 0.070 for the left eyes). However, SSc subgroup patients with none to mild eyelid thickening (50 %) had similar anterior segment parameters with control subjects (p > 0.05). Anterior chamber parameters of the SSc patients could show significant differences. These differences occur parallel to the eyelid changes but not secondary to it.
authors.affiliation: Department of Ophthalmology, Ataturk Teaching and Research Hospital, Yesilyurt, Izmir, Turkey. drsevincsahin@yahoo.com.
authors.forename: Sevinc
authors.initials: S
authors.lastname: Sahin Atik
authors.affiliation: Department of Ophthalmology, Ataturk Teaching and Research Hospital, Yesilyurt, Izmir, Turkey.
authors.forename: Feray
authors.initials: F
authors.lastname: Koc
authors.affiliation: Department of Internal Medicine, Bigadic Public Hospital, Balikesir, Turkey.
authors.forename: Sirin
authors.initials: S
authors.lastname: Akin Sari
authors.affiliation: Department of Ophthalmology, Ataturk Teaching and Research Hospital, Yesilyurt, Izmir, Turkey.
authors.forename: Nazife
authors.initials: N
authors.lastname: Sefi Yurdakul
authors.affiliation: Department of Internal Medicine, Division of Rheumatology, Ataturk Teaching and Research Hospital, Katip Celebi University, Yesilyurt, Izmir, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ozmen
authors.affiliation: Department of Internal Medicine, Division of Rheumatology, Ataturk Teaching and Research Hospital, Katip Celebi University, Yesilyurt, Izmir, Turkey.
authors.forename: Servet
authors.initials: S
authors.lastname: Akar
mesh_terms: D000328:Adult; D000869:Anterior Eye Segment / Q000000981:diagnostic imaging / Q000473:pathology*; D019781:Corneal Topography; D005141:Eyelid Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000175:diagnosis*; D012871:Skin Diseases / Q000175:diagnosis*; D014792:Visual Acuity / Q000502:physiology
keywords: Anterior chamber depth; Anterior segment parameters; Eyelid thickness; Systemic sclerosis