title: Current role of multiparametric magnetic resonance imaging for prostate cancer.
abstract: Multiparametric magnetic resonance imaging (mp-MRI) has shown promising results in diagnosis, localization, risk stratification and staging of clinically significant prostate cancer, and targeting or guiding prostate biopsy. mp-MRI consists of T2-weighted imaging (T2WI) combined with several functional sequences including diffusion-weighted imaging (DWI), perfusion or dynamic contrast-enhanced imaging (DCEI) and spectroscopic imaging. Recently, mp-MRI has been used to assess prostate cancer aggressiveness and to identify anteriorly located tumors before and during active surveillance. Moreover, recent studies have reported that mp-MRI is a reliable imaging modality for detecting local recurrence after radical prostatectomy or external beam radiation therapy. Because assessment on mp-MRI can be subjective, use of the newly developed standardized reporting Prostate Imaging and Reporting Archiving Data System (PI-RADS) scoring system and education of specialist radiologists are essential for accurate interpretation. This review focuses on the current place of mp-MRI in prostate cancer and its evolving role in the management of prostate cancer.
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Romaric
authors.initials: R
authors.lastname: Loffroy
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Chevallier
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Morgan
authors.initials: M
authors.lastname: Moulin
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Favelier
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Genson
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Pottecher
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Crehange
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Cochet
authors.affiliation: 1 Department of Vascular, Oncologic and Interventional Radiology, 2 Department of Urology and Andrology, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, François-Mitterrand Teaching Hospital, Dijon Cedex, France ; 3 Department of Radiation Oncology, 4 Department of Nuclear Medicine, LE2I UMR CNRS 6306, Arts et Métiers, University of Burgundy, Georges François Leclerc Cancer Center, Dijon, France.
authors.forename: Luc
authors.initials: L
authors.lastname: Cormier
keywords: Prostate cancer; active surveillance; diffusion imaging; functional imaging; multiparametric-MRI