title: Right Ventricular Ejection Fraction in Ischemic Versus Nonischemic Cardiomyopathy.
abstract: The relation between the etiology of cardiomyopathy and the function of the right ventricle (RV) has not been well described in the current era of 3-dimensional cardiac imaging. New advances in cardiac imaging with computed tomography (CT) have allowed accurate measurements of ejection fraction (EF), often a challenging task considering the unique RV shape. We evaluated 130 patients at the Loma Linda Veterans Affairs Healthcare System with cardiomyopathy and a left ventricular (LV) EF ≤ 40%. Etiology of cardiomyopathy was determined by CT angiography as ischemic (n = 56) or nonischemic (n = 74). RV volumes and RVEF were calculated based on 3-dimensional data set from CT images. Baseline LVEF was similar with a mean LVEF of 28% (± 6%) in the ischemic group and 28% (± 9%) in the nonischemic group (p = 0.46). RV function and volumes were moderately decreased in both cohorts, without significant difference between the groups (mean RVEF 34 ± 11% in ischemic group and 32 ± 10% in nonischemic group, p = 0.26). In conclusion, most patients with LV dysfunction also have RV dysfunction. The degree of RV dysfunction is not dependent on the etiology of cardiomyopathy.
authors.affiliation: Loma Linda University Health, Loma Linda, California. Electronic address: swasemiller@llu.edu.
authors.forename: Stephen
authors.initials: S
authors.lastname: Wasemiller
authors.affiliation: Loma Linda University Health, Loma Linda, California.
authors.forename: Tiffany
authors.initials: T
authors.lastname: Earle
authors.affiliation: Loma Linda University Health, Loma Linda, California; Veterans Affairs Loma Linda Healthcare System, Loma Linda, California.
authors.forename: Michael
authors.initials: M
authors.lastname: Kashner
authors.affiliation: Loma Linda University Health, Loma Linda, California; Veterans Affairs Loma Linda Healthcare System, Loma Linda, California.
authors.forename: Gary
authors.initials: G
authors.lastname: Foster
authors.affiliation: Loma Linda University Health, Loma Linda, California; Veterans Affairs Loma Linda Healthcare System, Loma Linda, California.
authors.forename: Helme
authors.initials: H
authors.lastname: Silvet
mesh_terms: D009202:Cardiomyopathies / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D012189:Retrospective Studies; D013318:Stroke Volume / Q000502:physiology*; D014057:Tomography, X-Ray Computed; D016278:Ventricular Function, Right / Q000502:physiology*