title: Cardiovascular disease in rheumatoid arthritis: Current perspectives on assessing and mitigating risk in clinical practice.
abstract: That individuals with rheumatoid arthritis (RA) have, on average, higher rates of events related to atherosclerotic vascular disease is now well documented and accepted. However, optimal ways to identify RA patients with atherosclerosis, and treat them to mitigate cardiovascular disease (CVD) risk have not been rigorously established. As such, current guidelines for CVD screening and prevention lack an evidence base. In the context of the current understanding of the determinants of atherosclerosis in RA and the current guidelines that have been published, this review focuses on strategies for identifying RA patients at risk of CVD events, and the possible primary and secondary prevention strategies that may be effective.
authors.affiliation: Division of Rheumatology, Columbia University, College of Physicians and Surgeons, 630 W 168th St., Physicians and Surgeons Building, Suite 10-445, New York, NY 10032, USA. Electronic address: jtg2122@columbia.edu.
authors.forename: Jon T
authors.initials: JT
authors.lastname: Giles
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D050197:Atherosclerosis / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D012307:Risk Factors
chemical_list: D018501:Antirheumatic Agents
keywords: Atherosclerosis; Cardiovascular imaging; Prediction; Rheumatoid arthritis; Risk algorithms; Screening