title: The mammography and MRI manifestations of adenomyoepithelioma of the breast.
abstract: OBJECTIVE
  To investigate mammography and magnetic resonance imaging (MRI) manifestations of benign and malignant adenomyoepithelioma (AME), in order to improve our understanding of this disease.
  
  
  METHODS
  Thirteen patients (11 cases of benign AME and two cases of malignant AME) were included. All patients underwent preoperative mammography, and four underwent preoperative MRI examinations.
  
  
  RESULTS
  Mammography revealed that 11 cases showed round, lobulate, or oval masses. One case was accompanied by calcification with blurred edges; the remaining 10 cases showed masses with clear or shaded borders. One case exhibited structurally distorted lesions, and another showed focal opacities. Among the four patients who also underwent preoperative MRI examinations, signals in the three benign cases were clearly enhanced homogeneously, and the dynamic enhancement curves were progressive. The one case of malignant AME showed an irregularly shaped mass with spiculate margins on the MRI images. The signals were homogeneously enhanced, and the dynamic enhancement curve was of the washout type.
  
  
  CONCLUSIONS
  AME usually exhibited oval or round masses with smooth edges and no calcification, and, in a portion of the cases, structurally distorted lesions or focal opacities. On different MRI sequences, AME usually showed homogeneous signal. The apparent diffusion coefficient value of malignant AME is relatively low.
authors.affiliation: Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: G
authors.initials: G
authors.lastname: Qin
authors.affiliation: Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Z
authors.initials: Z
authors.lastname: He
authors.affiliation: Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Electronic address: Chenweiguo1964@21cn.com.
authors.forename: W
authors.initials: W
authors.lastname: Chen
authors.affiliation: Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. Electronic address: yanglei@fimmu.com.
authors.forename: L
authors.initials: L
authors.lastname: Yang
mesh_terms: D055331:Adenomyoepithelioma / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D003287:Contrast Media; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008327:Mammography; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media