title: Bladder Leiomyosarcoma 25 Years after Treatment with Cyclophosphamide in Patient with History of Retinoblastoma.
abstract: The objective of this case report is to present a rare bladder tumour in a young patient 25 years after the treatment with cyclophosphamide because of a neuroblastoma of the right eye. The first symptom of the tumour was macroscopic haematuria with dysuria and pollakiuria. The final diagnosis was dictaminated by the pathologist and the best treatment option was radical cystoprostatectomy. Leiomyosarcoma was presented in a 26-year-old patient like the third different tumour, the second was an esphenoidal meningioma. At the 8th year of follow-up after the radical surgery, the patient is free of bladder disease. Bladder leiomyosarcoma is a rare tumour of the bladder and its early diagnosis and treatment are mandatory for best prognosis.
authors.affiliation: Department of Urologist, Hospital de Mataró, Consorci Sanitari del Maresme, Mataró, Barcelona, Spain.
authors.forename: Cristóbal
authors.initials: C
authors.lastname: Ramírez Sevilla
authors.forename: Carme
authors.initials: C
authors.lastname: Admella-Salvador
authors.forename: Jose-Antonio
authors.initials: JA
authors.lastname: Romero-Martin
authors.forename: Juan
authors.initials: J
authors.lastname: Llopis-Manzanera
authors.forename: Miguel-Angel
authors.initials: MA
authors.lastname: Barranco-Sanz
mesh_terms: D000328:Adult; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000601:surgery; D019572:Retinal Neoplasms / Q000628:therapy; D012175:Retinoblastoma / Q000628:therapy; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000601:surgery
chemical_list: D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide
keywords: Bladder leiomyosarcoma; Cyclophosphamide; Cystectomy; Retinoblastoma