title: Bladder Wall Telangiectasia in a Patient with Ataxia-Telangiectasia and How to Manage?
abstract: Ataxia-telangiectasia (A-T) is a rare neurodegenerative, inherited disease causing severe morbidity. Oculocutaneous telangiectasias are almost constant findings among the affected cases as telangiectasia is considered the main clinical finding for diagnosis. Vascular abnormalities in organs have been reported infrequently but bladder wall telangiectasias are extremely rare. We aimed to report recurrent hemorrhage from bladder wall telangiectasia in a 9-year-old boy with A-T who had received intravenous cyclophosphamide for non-Hodgkin's lymphoma. Since A-T patients are known to be more susceptible to chemical agents, we suggested that possibly cyclophosphamide was the drug which induced bladder wall injury in this patient.
authors.affiliation: Department of Pediatric Infectious Diseases, Clinical Immunology and Allergy, Istanbul University, Cerrahpasa Medical Faculty, 34098 Istanbul, Turkey.
authors.forename: Fatma Deniz
authors.initials: FD
authors.lastname: Aygün
authors.affiliation: Department of Pediatric Infectious Diseases, Clinical Immunology and Allergy, Istanbul University, Cerrahpasa Medical Faculty, 34098 Istanbul, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Nepesov
authors.affiliation: Department of Pediatric Infectious Diseases, Clinical Immunology and Allergy, Istanbul University, Cerrahpasa Medical Faculty, 34098 Istanbul, Turkey.
authors.forename: Haluk
authors.initials: H
authors.lastname: Çokuğraş
authors.affiliation: Department of Pediatric Infectious Diseases, Clinical Immunology and Allergy, Istanbul University, Cerrahpasa Medical Faculty, 34098 Istanbul, Turkey.
authors.forename: Yıldız
authors.initials: Y
authors.lastname: Camcıoğlu