title: Liver Transplantation Outcomes Using Grafts From Donors Older Than the Age of 80 Years.
abstract: We performed a retrospective cohort study between 2002 and 2014 to compare liver transplantation outcomes between recipients of grafts from donors older than and younger than the age of 80 years. Numerical variables were compared with the Student t test when their distribution was normal and the Mann-Whitney test when it was not, whereas categorical variables were compared with Pearson chi-squared test or Fisher test, as appropriate; P < .05 was considered significant. The study included 312 patients with organs from donors younger than 80 years of age and 17 with organs from older donors. The 2 recipient groups did not significantly differ in weight, height, gender, body mass index (BMI), CHILD or MELD score, intensive care unit (ICU) or hospital stay, need for intraoperative hemoderivatives, postreperfusion syndrome, biliary or vascular complications, ischemic cholangiopathy, number of repeat surgeries, graft rejection, retransplantation, or survival at 6 months. Although earlier studies considered livers from elderly donors to be suboptimal, our results support the proposition that octogenarian donors can be an excellent source of liver grafts.
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain. Electronic address: andrea_vrgranada@hotmail.com.
authors.forename: A V
authors.initials: AV
authors.lastname: Rabelo
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: M J
authors.initials: MJ
authors.lastname: Alvarez
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: C S M
authors.initials: CS
authors.lastname: Méndez
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: M T
authors.initials: MT
authors.lastname: Villegas
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: K
authors.initials: K
authors.lastname: MGraneroa
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Becerra
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Dominguez
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: A M
authors.initials: AM
authors.lastname: Raya
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Exposito
authors.affiliation: Hospital Universitario de Granada, Cirugía General y Digestiva, Granada, Spain.
authors.forename: Y F
authors.initials: YF
authors.lastname: Suárez
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D002648:Child; D005260:Female; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D007902:Length of Stay; D008099:Liver / Q000601:surgery; D016031:Liver Transplantation / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014019:Tissue Donors / Q000706:statistics & numerical data*; D019737:Transplants; D016896:Treatment Outcome