title: The Evolution of Pediatric Soft Tissue Sarcoma Classification in the Last 50 Years.
abstract: This review discusses the history of the classification of soft tissue sarcomas in children and adolescents, the current transition toward integration of morphology and molecular genetics as new entities emerge, and future perspectives.
authors.affiliation: 1 Department of Medicine-DIMED, Pathology Unit, University of Padova, Via Gabelli, 61 35124, Padova, Italy.
authors.forename: Rita
authors.initials: R
authors.lastname: Alaggio
authors.affiliation: 2 Department of Pathology, Vanderbilt Medical Center, 1161 21st Avenue South, Nashville, TN 37232, USA.
authors.forename: Cheryl M
authors.initials: CM
authors.lastname: Coffin
mesh_terms: D000293:Adolescent; D014408:Biomarkers, Tumor / Q000235:genetics; D002648:Child; D005354:Fibrosarcoma / Q000145:classification / Q000473:pathology; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D025202:Molecular Diagnostic Techniques; D019042:Muscle Neoplasms / Q000145:classification* / Q000235:genetics / Q000266:history / Q000473:pathology*; D018482:Muscle, Skeletal / Q000473:pathology; D018317:Nerve Sheath Neoplasms / Q000145:classification / Q000473:pathology; D057089:Pathology, Molecular / Q000266:history; D010372:Pediatrics / Q000266:history; D012509:Sarcoma / Q000145:classification* / Q000235:genetics / Q000266:history / Q000473:pathology*; D009626:Terminology as Topic
chemical_list: D014408:Biomarkers, Tumor
keywords: fibrosarcoma; rhabdomyosarcoma; sarcoma classification; soft tissue tumors; undifferentiated sarcoma