title: Artifact free reconstruction with the system matrix approach by overscanning the field-free-point trajectory in magnetic particle imaging.
abstract: Magnetic particle imaging is a tracer-based imaging method that utilizes the non-linear magnetization response of iron-oxide for determining their spatial distribution. The method is based on a sampling scheme where a sensitive spot is moved along a trajectory that captured a predefined field-of-view (FOV). However, particles outside the FOV also contribute to the measurement signal due to their rotation and the non-sharpness of the sensitive spot. In the present work we investigate artifacts that are induced by particles not covered by the FOV and show that the artifacts can be mitigated by using a system matrix that covers not only the region of interest but also a certain area around the FOV. The findings are especially relevant when using a multi-patch acquisition scheme where the boundaries of neighboring patches have to be handled.
authors.affiliation: Bruker Biospin MRI GmbH, Rudolf-Plank-Str. 23, 76275 Ettlingen, Germany. Institute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Weber
authors.forename: F
authors.initials: F
authors.lastname: Werner
authors.forename: J
authors.initials: J
authors.lastname: Weizenecker
authors.forename: T M
authors.initials: TM
authors.lastname: Buzug
authors.forename: T
authors.initials: T
authors.lastname: Knopp
mesh_terms: D016477:Artifacts; D003952:Diagnostic Imaging / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D052203:Ferrosoferric Oxide / Q000493:pharmacokinetics*; D006801:Humans; D060526:Magnetic Fields; D019047:Phantoms, Imaging
chemical_list: D052203:Ferrosoferric Oxide