title: Patterns of Chronic Conditions and Their Associations With Behaviors and Quality of Life, 2010.
abstract: BACKGROUND
  Co-occurring chronic health conditions elevate the risk of poor health outcomes such as death and disability, are associated with poor quality of life, and magnify the complexities of self-management, care coordination, and treatment planning. This study assessed patterns of both singular and multiple chronic conditions, behavioral risk factors, and quality of life in a population-based sample.
  
  
  METHODS
  In a national survey, adults (n = 4,184) answered questions about the presence of 27 chronic conditions. We used latent class analysis to identify patterns of chronic conditions and to explore associations of latent class membership with sociodemographic characteristics, behavioral risk factors, and health.
  
  
  RESULTS
  Latent class analyses indicated 4 morbidity profiles: a healthy class (class 1), a class with predominantly physical health conditions (class 2), a class with predominantly mental health conditions (class 3), and a class with both physical and mental health conditions (class 4). Class 4 respondents reported significantly worse physical health and well-being and more days of activity limitation than those in the other latent classes. Class 4 respondents were also more likely to be obese and sedentary, and those with predominantly mental health conditions were most likely to be current smokers.
  
  
  CONCLUSIONS
  Subgroups with distinct patterns of chronic conditions can provide direction for screening and surveillance, guideline development, and the delivery of complex care services.
authors.affiliation: Department of Psychology, University of Hawai'i at Mānoa, 2530 Dole St, Sakamaki C400, Honolulu, HI 96822. Email: Barile@hawaii.edu.
authors.forename: John P
authors.initials: JP
authors.lastname: Barile
authors.affiliation: National Cancer Institute, Rockville, Maryland.
authors.forename: Sandra A
authors.initials: SA
authors.lastname: Mitchell
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: William W
authors.initials: WW
authors.lastname: Thompson
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia.
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Zack
authors.affiliation: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
authors.forename: Bryce B
authors.initials: BB
authors.lastname: Reeve
authors.affiliation: Northwestern University, Chicago, Illinois.
authors.forename: David
authors.initials: D
authors.lastname: Cella
authors.affiliation: National Cancer Institute, Rockville, Maryland.
authors.forename: Ashley Wilder
authors.initials: AW
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D015438:Health Behavior; D006304:Health Status; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D009765:Obesity; D011788:Quality of Life; D012307:Risk Factors; D057185:Sedentary Behavior; D012648:Self Care; D012907:Smoking; D014481:United States; D055815:Young Adult