title: Does measurement of intrauterine pressure have predictive value during oxytocin-augmented labor?
abstract: OBJECTIVE
  In a previous randomized trial that compared monitoring uterine contractions with an intrauterine pressure catheter (IUPC) versus external monitoring, we demonstrated that use of an IUPC did not improve the outcome of labor. To provide insight in the lack of a positive effect, we evaluated level of IUP in Montevideo units (MU) in correlation with dysfunctional labor and adverse neonatal outcome.
  
  
  METHODS
  Here, we present two secondary analyses on the 503 women who had IUP measured in the trial. Firstly, we assessed labor outcome in relation to the highest IUP measured at any time during labor. Secondly, we assessed labor outcome to the IUP registered at the last vaginal examination during the first stage of labor in two study groups (above and below 200 MU).
  
  
  RESULTS
  Women with lower IUP were statistically significant older, had pregnancies with a longer gestational age, longer labors and neonates with a higher birth weight. The risk of a cesarean section was higher in women who had low IUP during labor (Likelihood Ratio 1.6 for IUP < 100 MU, 0.41 for IUP > 300 MU). IUP was not associated with neonatal outcome.
  
  
  CONCLUSIONS
  IUP is associated with mode of delivery. However, use of internal tocodynamometry does not improve birth outcomes.
authors.affiliation: a The Robinson Research Institute, School of Paediatrics and Reproductive Health, University of Adelaide and the South Australian Health and Medical Research Institute Adelaide , Adelaide , Australia .
authors.forename: Ben Willem J
authors.initials: BW
authors.lastname: Mol
authors.affiliation: b Department of Obstetrics and Gynecology , Onze Lieve Vrouwe Gasthuis , Amsterdam , the Netherlands .
authors.forename: Sabine L M
authors.initials: SL
authors.lastname: Logtenberg
authors.affiliation: c Department of Obstetrics and Gynecology , Máxima Medical Center , Veldhoven , the Netherlands .|d Department of Midwifery Science , AVAG/EMGO Institute for Health and Care Research, VU University Medical Center , Amsterdam , the Netherlands .
authors.forename: Corine J M
authors.initials: CJ
authors.lastname: Verhoeven
authors.affiliation: e Department of Obstetrics and Gynecology , Leiden University Medical Center , Leiden , the Netherlands .
authors.forename: Kitty W M
authors.initials: KW
authors.lastname: Bloemenkamp
authors.affiliation: f Department of Obstetrics and Gynecology , AMPHIA Hospital Breda , Breda , the Netherlands , and.
authors.forename: Dimitri N M
authors.initials: DN
authors.lastname: Papatsonis
authors.affiliation: g Department of Obstetrics and Gynecology , Academic Medical Center , Amsterdam , the Netherlands.
authors.forename: Jannet J H
authors.initials: JJ
authors.lastname: Bakker
authors.affiliation: g Department of Obstetrics and Gynecology , Academic Medical Center , Amsterdam , the Netherlands.
authors.forename: Joris A M
authors.initials: JA
authors.lastname: van der Post
mesh_terms: D000328:Adult; D002585:Cesarean Section / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007751:Labor, Induced / Q000295:instrumentation*; D010121:Oxytocin; D011237:Predictive Value of Tests; D011247:Pregnancy; D011312:Pressure; D018590:Uterine Monitoring
chemical_list: D010121:Oxytocin
keywords: Intrauterine pressure; mode of delivery; pressure catheter