title: Novel skeleton compound Allomyrinanoid A and two purine alkaloids from the adult of Allomyrina dichotoma L.
abstract: Three new compounds were isolated from the adult insect of Allomyrina dichotoma L. for the first time. A new skeleton compound is named as Allomyrinanoid A (1) originated from the familiar norbornane derivatives and two new compounds of purine alkaloid are named as adenine-9-methylaldehyde oxime B (2) and 6-N-methyleneimine-adenine-9-methylaldehyde oxime B (3). The compounds (2) and (3) are the tautomers of imine-enamine and creatively separated form the solvent using column chromatography method. The structures of all isolated compounds were established by spectroscopic methods including analyses of their 1D, 2D NMR and HRESI-MS data, and confirmed by comparison of the literature data. These new components displayed antibacterial activities against both Gram-positive and Gram-negative strain.
authors.affiliation: School of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology, Luoyang, Henan 471023, PR China. Electronic address: lanlanniu@163.com.
authors.forename: Lanlan
authors.initials: L
authors.lastname: Niu
authors.affiliation: School of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology, Luoyang, Henan 471023, PR China. Electronic address: cruise1024@163.com.
authors.forename: Jiayu
authors.initials: J
authors.lastname: Gao
authors.affiliation: School of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology, Luoyang, Henan 471023, PR China. Electronic address: 1157382625@qq.com.
authors.forename: Haidi
authors.initials: H
authors.lastname: Li
authors.affiliation: School of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology, Luoyang, Henan 471023, PR China. Electronic address: junenutty@126.com.
authors.forename: Junna
authors.initials: J
authors.lastname: Liu
authors.affiliation: School of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology, Luoyang, Henan 471023, PR China. Electronic address: yinwp@haust.edu.cn.
authors.forename: Weiping
authors.initials: W
authors.lastname: Yin
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D001517:Coleoptera / Q000737:chemistry*; D009636:Norbornanes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D011687:Purines / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D000900:Anti-Bacterial Agents; D009636:Norbornanes; D011687:Purines; C030985:purine
keywords: 6-N-Methyleneimine-adenine-9-methylaldehyde oxime B; Adenine-9-methylaldehyde oxime B; Allomyrinanoid A; Insect Allomyrina dichotoma L.; Natural products; New skeleton compound