title: Understanding why low-risk patients accept vaccines: a socio-behavioral approach.
abstract: BACKGROUND
  Vaccines are one of the most important public health interventions. Understanding factors associated with vaccine acceptance is critical. The objectives of this study were to evaluate the impact of the three constructs of the Theory of Planned Behavior (TPB) on the intention to be vaccinated among healthy individuals being seen for pre-travel care, and to evaluate if behavioral intention was associated with vaccine acceptance.
  
  
  METHODS
  We surveyed individuals seeking vaccination at the University of Louisville Vaccine and International Health and Travel Clinic. Linear and two stage least squares regression models were used to define the associations between constructs of the TPB and the intention to be vaccinated, as well as the association between the intention to be vaccinated and vaccine acceptance.
  
  
  RESULTS
  A total of 183 individuals were included in the analysis. None of the constructs of the TPB were associated with intention to be vaccinated. Behavioral intention was not associated with vaccination acceptance.
  
  
  CONCLUSIONS
  This study suggests that the TPB does not predict the intention to get vaccinated among individuals attending our Vaccine and International Health and Travel Clinic. It will be critical to define better predictors of vaccine uptake in healthy, low-risk individuals to increase vaccine acceptance.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, KY, 40202, USA. tlwiem01@louisville.edu.|Computational Epidemiology Unit, University of Louisville Division of Infectious Diseases, Global Health Research Organization, 501 E Broadway Suite 140B, Louisville, KY, 40202, USA. tlwiem01@louisville.edu.
authors.forename: Timothy L
authors.initials: TL
authors.lastname: Wiemken
authors.affiliation: Department of Medicine, Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, KY, 40202, USA. ruth.carrico@louisville.edu.
authors.forename: Ruth M
authors.initials: RM
authors.lastname: Carrico
authors.affiliation: Department of Medicine, Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, KY, 40202, USA. rrkell01@louisville.edu.
authors.forename: Robert R
authors.initials: RR
authors.lastname: Kelley
authors.affiliation: Department of Medicine, Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, KY, 40202, USA. lebinf01@louisville.edu.
authors.forename: Laura E
authors.initials: LE
authors.lastname: Binford
authors.affiliation: Department of Medicine, Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, KY, 40202, USA. p0peyr01@louisville.edu.
authors.forename: Paula
authors.initials: P
authors.lastname: Peyrani
authors.affiliation: Pfizer Inc., Collegeville, PA, USA. kimbal.d.ford@pfizer.com.
authors.forename: Kimbal D
authors.initials: KD
authors.lastname: Ford
authors.affiliation: Pfizer Inc., Collegeville, PA, USA. Verna.Welch@pfizer.com.
authors.forename: Verna
authors.initials: V
authors.lastname: Welch
authors.affiliation: Department of Medicine, Division of Infectious Diseases, University of Louisville School of Medicine, Louisville, KY, 40202, USA. jarami01@louisville.edu.
authors.forename: Julio A
authors.initials: JA
authors.lastname: Ramirez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D015438:Health Behavior; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000523:psychology*; D012306:Risk; D014611:Vaccination / Q000523:psychology*; D055815:Young Adult