title: The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis.
abstract: The present study aimed to comprehensively assess if oats intake is beneficial for diabetic patients. The literature search was conducted in PubMed database up to 23 August 2015. Fourteen controlled trials and two uncontrolled observational studies were included. Compared with the controls, oats intake significantly reduced the concentrations of glycosylated hemoglobin A1c (HbA1c) (MD, -0.42%; 95% CI, -0.61% to -0.23%), fasting blood glucose (FBG) (MD, -0.39 mmol/L; 95% CI, -0.58 to -0.19 mmol/L), total cholesterol (TC) (MD, -0.49 mmol/L; 95% CI, -0.86 to -0.12 mmol/L), low-density lipoprotein cholesterol (LDL-C) (MD, -0.29 mmol/L; 95% CI, -0.48 to -0.09 mmol/L). Oatmeal significantly reduced the acute postprandial glucose and insulin responses compared with the control meal. The present study has revealed a beneficial effect of oats intake on glucose control and lipid profiles in type 2 diabetic patients. Further investigations of oats intake in patients with type 1 diabetes and the safety of oats consumption are required.
authors.affiliation: Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China. qingtao1990@sina.com.
authors.forename: Qingtao
authors.initials: Q
authors.lastname: Hou
authors.affiliation: Department of Endocrinology and Metabolism, The Third People's Hospital of Chengdu, Chengdu 610031, China. lyhelen37@126.com.
authors.forename: Yun
authors.initials: Y
authors.lastname: Li
authors.affiliation: Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China. ebmliling@hotmail.com.
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Clinical Nutrition, West China Hospital, Sichuan University, Chengdu 610041, China. hellochgp@163.com.
authors.forename: Gaiping
authors.initials: G
authors.lastname: Cheng
authors.affiliation: Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China. sunx79@hotmail.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Sun
authors.affiliation: Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China. lisheyu@gmail.com.
authors.forename: Sheyu
authors.initials: S
authors.lastname: Li
authors.affiliation: Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China. hmtian999@126.com.
authors.forename: Haoming
authors.initials: H
authors.lastname: Tian
mesh_terms: D018554:Avena; D001786:Blood Glucose / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D016208:Databases, Factual; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000178:diet therapy*; D004032:Diet; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000097:blood; D064887:Observational Studies as Topic; D019518:Postprandial Period; D016032:Randomized Controlled Trials as Topic; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D006442:Glycated Hemoglobin; D007328:Insulin; D014280:Triglycerides
keywords: cholesterol; glycemic control; meta-analysis; oats; systematic review; type 2 diabetes mellitus; β-glucan