title: Effect of a 12-Week Low vs. High Intensity Aerobic Exercise Training on Appetite-Regulating Hormones in Obese Adolescents: A Randomized Exercise Intervention Study.
abstract: Little is known about how the intensity of aerobic training influences appetite-regulating hormones in obese adolescents. Our goal was to assess the effect of low and high intensity aerobic trainings on food intake and appetite-regulating hormones in obese adolescents. Forty three obese adolescents (age: 13-18y, BMI: 34.48 ± 3.94 kg/m2) were randomized into high intensity training (HIT; n = 20) or low intensity training (LIT; n = 23) groups for 12 weeks. All participants also received the same nutritional, psychological and clinical counseling. Pre- and postintervention energy intake (EI) and circulating levels of insulin, leptin, peptide YY3-36 (PYY3-36) and ghrelin were measured. Adolescents in the HIT showed a reduction in total EI and an increase in PYY3-36 (p < .05). Aerobic exercise training performed at ventilatory threshold 1 intensity, reduced EI and augmented PYY3-36 in obese adolescents, compared with LIT. The data suggest that HIT and LIT have differential effects in the regulation of appetite signals and subsequent EI in obese adolescents.
authors.affiliation: Dept. of Human Movement Sciences, Federal University of São Paulo, Federal University of São Paulo, Brazil.
authors.forename: Wagner Luiz
authors.initials: WL
authors.lastname: Prado
authors.forename: Mara Cristina
authors.initials: MC
authors.lastname: Lofrano-Prado
authors.forename: Lila Missae
authors.initials: LM
authors.lastname: Oyama
authors.forename: Michelle
authors.initials: M
authors.lastname: Cardel
authors.forename: Priscyla Praxedes
authors.initials: PP
authors.lastname: Gomes
authors.forename: Maria Laura S S
authors.initials: ML
authors.lastname: Andrade
authors.forename: Camila R M
authors.initials: CR
authors.lastname: Freitas
authors.forename: Prabhakaran
authors.initials: P
authors.lastname: Balagopal
authors.forename: James O
authors.initials: JO
authors.lastname: Hill
mesh_terms: D000293:Adolescent; D015308:Anaerobic Threshold / Q000502:physiology; D004435:Eating; D002149:Energy Intake; D015444:Exercise / Q000502:physiology*; D005260:Female; D054439:Ghrelin / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000097:blood; D008297:Male; D063766:Pediatric Obesity / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood; D019894:Peptide YY / Q000097:blood; D064797:Physical Conditioning, Human / Q000379:methods* / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*
chemical_list: D054439:Ghrelin; D007328:Insulin; D020738:Leptin; D010446:Peptide Fragments; D019894:Peptide YY; C061785:peptide YY (3-36)