title: Assessment of Hematological Factors Involved in Development and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss.
abstract: OBJECTIVE
  The aim of this study was to investigate the possible effects of routine hematological parameters on the development and prognosis of idiopathic sudden sensorineural hearing loss in patients applying to our clinic.
  
  
  METHODS
  A retrospective clinical study.
  
  
  METHODS
  One academic health center from 2008 to 2014.
  
  
  METHODS
  One hundred forty patients with sudden hearing loss and 132 healthy controls were included in the present study.
  
  
  RESULTS
  Patients having idiopathic sudden sensorineural hearing loss were divided into 2 subgroups based on whether they recovered (complete, partial, and slight recovery) (Group 1; n = 83, 59.3%) or not (Group 2; n = 57, 40.7%) during the follow-up term. Group 1, Group 2, and the controls differed statistically significantly in terms of neutrophil-to-lymphocyte ratio (P = 0.001), platelet-to-lymphocyte ratio (P = 0.001), lymphocytes % (P = 0.001), mean corpuscular hemoglobin (P = 0.019), mean corpuscular hemoglobin concentration (P = 0.015), platelet (P  = 0.001), mean platelet volume (P = 0.001), platelet distribution width (P = 0.009), and glucose (P = 0.001). The study groups and the controls did not have any significant difference in terms of other laboratory parameters affecting the prognosis of Idiopathic sudden sensorineural hearing loss.
  
  
  CONCLUSIONS
  The results the authors obtained showed that laboratory parameters such as lymphocyte, lymphocyte%, platelet, mean platelet volume, platelet distribution width, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration may be indicative for prognosis and treatment success in groups of patients suffering idiopathic sudden sensorineural hearing loss in whose etiology many factors play a role.
authors.affiliation: *Department of Otolaryngology †Department of Internal Medicine, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey.
authors.forename: Kasim
authors.initials: K
authors.lastname: Durmuş
authors.forename: Hatice
authors.initials: H
authors.lastname: Terzi
authors.forename: Tuba Doğan
authors.initials: TD
authors.lastname: Karataş
authors.forename: Mansur
authors.initials: M
authors.lastname: Doğan
authors.forename: Ismail Önder
authors.initials: IÖ
authors.lastname: Uysal
authors.forename: Mehmet
authors.initials: M
authors.lastname: Şencan
authors.forename: Emine Elif
authors.initials: EE
authors.lastname: Altuntaş
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D001792:Blood Platelets / Q000473:pathology; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D006319:Hearing Loss, Sensorineural / Q000097:blood*; D003639:Hearing Loss, Sudden / Q000097:blood*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007958:Leukocyte Count; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology; D010976:Platelet Count; D011379:Prognosis; D020127:Recovery of Function; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D006454:Hemoglobins