title: Microcatheter-assisted trabeculotomy versus rigid probe trabeculotomy in childhood glaucoma.
abstract: To compare microcatheter-assisted trabeculotomy with standard rigid probe trabeculotomy for the treatment of childhood glaucoma.
  
  
  
  The early postoperative (12 months) results of microcatheter-assisted trabeculotomy (group 1) performed by single surgeon were retrospectively compared with those of rigid probe trabeculotomy (group 2) performed by the same surgeon in patients treated for childhood glaucoma. Success was defined as an intraocular pressure (IOP) <21 mm Hg with at least a 30% reduction from preoperative IOP with (qualified success) or without (complete success) the use of anti-glaucoma medication.
  
  
  
  A total of 43 eyes of 36 patients were included. Mean IOP in group 1 was significantly lower than that in group 2 at 6 months (17.0±5.1 vs 22.5±9.8; p=0.042), 9 months (16.3±5.0 vs 21.6±9.6; p=0.009) and 12 months (14.8±2.5 vs 19.0±7.1; p=0.049) postoperatively. The mean percentage reduction in IOP from preoperative to the last postoperative follow-up was greater in group 1 (47.3±17.7%) than in group 2 (34.2±21.9%) (p=0.036). group 1 demonstrated an 81.0% complete and 86.4% qualified success rate, exceeding the 51.6% complete (p=0.060) and 61.9% qualified (p=0.037) success rate of group 2. There were no long-term complications in either group, but choroidal detachment occurred in one eye in group 2.
  
  
  
  Microcatheter-assisted circumferential trabeculotomy is a more effective treatment and is as safe as traditional trabeculotomy with a rigid probe for primary congenital glaucoma in the early postoperative course.
  
  
  
  ChiCTR-OCC-15005789, Results.
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Huaizhou
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
authors.forename: Jia
authors.initials: J
authors.lastname: Yin
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Li
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Xifang
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Ophthalmology, Beijing Anzhen Hospital, Beijing, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Xin
authors.affiliation: Department of Ophthalmology, First People's Hospital of Xuzhou, Xuzhou, China.
authors.forename: Xiaoya
authors.initials: X
authors.lastname: Chen
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Ningli
authors.initials: N
authors.lastname: Wang
mesh_terms: D002404:Catheterization / Q000295:instrumentation*; D057785:Catheters; D002675:Child, Preschool; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure; D008297:Male; D008904:Miniaturization; D011184:Postoperative Period; D012189:Retrospective Studies; D013997:Time Factors; D014130:Trabeculectomy / Q000295:instrumentation*; D016896:Treatment Outcome
keywords: Child health (paediatrics); Glaucoma