title: Use of nesiritide in critically ill children with biventricular dysfunction suffering from oliguria despite standard heart-failure management.
abstract: Although nesiritide has been used in adults with left heart failure, the experience in the paediatric population is limited. We reviewed and analysed our experience with continuous nesiritide infusion as adjunct therapy in children with biventricular dysfunction due to diverse aetiologies and suffering from oliguria despite intravenous diuretics and inotropic therapies for heart-failure management.
authors.affiliation: 1Department of Pediatrics,Children's Medical Center,UT Southwestern Medical Center,Dallas,Texas,United States of America.
authors.forename: Bibhuti B
authors.initials: BB
authors.lastname: Das
authors.affiliation: 1Department of Pediatrics,Children's Medical Center,UT Southwestern Medical Center,Dallas,Texas,United States of America.
authors.forename: Joshua
authors.initials: J
authors.lastname: Koch
authors.affiliation: 1Department of Pediatrics,Children's Medical Center,UT Southwestern Medical Center,Dallas,Texas,United States of America.
authors.forename: Vivian
authors.initials: V
authors.lastname: Dimas
authors.affiliation: 2Department of Cardiovascular and Thoracic Surgery,Children's Medical center,UT Southwestern Medical center,Dallas,Texas,United States of America.
authors.forename: Kristine
authors.initials: K
authors.lastname: Guleserian
authors.affiliation: 1Department of Pediatrics,Children's Medical Center,UT Southwestern Medical Center,Dallas,Texas,United States of America.
authors.forename: Alan
authors.identifier: http://orcid.org/0000-0003-3535-8128
authors.initials: A
authors.lastname: Nugent
mesh_terms: D000293:Adolescent; D002648:Child; D016638:Critical Illness; D006333:Heart Failure / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D045283:Natriuretic Agents / Q000627:therapeutic use*; D020097:Natriuretic Peptide, Brain / Q000627:therapeutic use*; D009846:Oliguria / Q000209:etiology; D018754:Ventricular Dysfunction / Q000188:drug therapy* / Q000209:etiology
chemical_list: D045283:Natriuretic Agents; D020097:Natriuretic Peptide, Brain
keywords: B-type natriuretic peptide; left ventricular assist device; nesiritide; paediatric heart failure; total artificial heart