title: [RESEARCH PROGRESS OF CONTROLLED RELEASING DELIVERY OF BIOLOGICAL FACTORS FOR CARTILAGE REPAIR].
abstract: OBJECTIVE
  To summarize the recent progress of the controlled releasing delivery of biological factors for cartilage repair.
  
  
  METHODS
  The recently published literature at home and abroad on the controlled releasing delivery of biological factors for cartilage repair was reviewed and summarized.
  
  
  RESULTS
  Various biological factors have been applied for repairing cartilage. For better cartilage repair effects, controlled releasing delivery of biological factors can be applied by means of combining biological factors with degradable biomaterials, or by micro- and nano-particles. Meanwhile, multiple biologic delivery and temporally controlled delivery are also inevitable choices.
  
  
  CONCLUSIONS
  Although lots of unsolved problems exist, the controlled releasing delivery of biological factors has been a research focus for cartilage repair because of the controllability and delicacy.
authors.forename: Jialei
authors.initials: J
authors.lastname: Chen
authors.forename: Zhou
authors.initials: Z
authors.lastname: Xiang
mesh_terms: D001672:Biocompatible Materials / Q000008:administration & dosage*; D001685:Biological Factors / Q000008:administration & dosage*; D002356:Cartilage / Q000187:drug effects / Q000378:metabolism*; D003692:Delayed-Action Preparations; D006801:Humans; D023822:Tissue Engineering / Q000379:methods / Q000639:trends
chemical_list: D001672:Biocompatible Materials; D001685:Biological Factors; D003692:Delayed-Action Preparations