title: Actin and Apical Constriction: Some (Re)-Assembly Required.
abstract: Linkage of the actomyosin cytoskeleton to cell-cell junctions drives cell shape change in development and homeostasis. In this issue of Developmental Cell, Jodoin et al. (2015) provide new insights into the underlying mechanisms, revealing that factors driving actin filament disassembly and thus dynamics also play key roles in apical constriction.
authors.affiliation: Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: asprack@email.unc.edu.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Spracklen
authors.affiliation: Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: peifer@unc.edu.
authors.forename: Mark
authors.initials: M
authors.lastname: Peifer
mesh_terms: D000199:Actins / Q000378:metabolism*; D022005:Adherens Junctions / Q000378:metabolism*; D000818:Animals; D003599:Cytoskeleton / Q000378:metabolism*; D004847:Epithelial Cells / Q000378:metabolism*; D004848:Epithelium / Q000378:metabolism*
chemical_list: D000199:Actins