title: Photobiomodulation in promoting wound healing: a review.
abstract: Despite diverse methods being applied to induce wound healing, many wounds remain recalcitrant to all treatments. Photobiomodulation involves inducing wound healing by illuminating wounds with light emitting diodes or lasers. While used on different animal models, in vitro, and clinically, wound healing is induced by many different wavelengths and powers with no optimal set of parameters yet being identified. While data suggest that simultaneous multiple wavelength illumination is more efficacious than single wavelengths, the optimal single and multiple wavelengths must be better defined to induce more reliable and extensive healing of different wound types. This review focuses on studies in which specific wavelengths induce wound healing and on their mechanisms of action.
authors.affiliation: Institute of Neurobiology, University of Puerto Rico, 201 Calle Norzagaray, San Juan 00901, Puerto Rico.
authors.forename: Damien P
authors.initials: DP
authors.lastname: Kuffler
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D005786:Gene Expression Regulation / Q000528:radiation effects; D006801:Humans; D008027:Light; D028022:Low-Level Light Therapy; D000066829:Neuroprotection / Q000187:drug effects; D014945:Wound Healing / Q000235:genetics / Q000528:radiation effects*
chemical_list: D000900:Anti-Bacterial Agents
keywords: HBOT; LED; LLLT; diabetic ulcer; infrared laser; laser light; wound healing