title: Treatment Outcomes of Childhood TB in Lagos, Nigeria.
abstract: BACKGROUND
  : Treatment outcomes of tuberculosis (TB) in children are rarely evaluated by most national TB programmes in sub-Saharan Africa. This study evaluated the treatment outcomes of children treated for TB in Lagos State, Nigeria.
  
  
  METHODS
  A retrospective review of programme data of the Lagos state TB and the Leprosy control programme in Nigeria from 1 January 2012 to 31 December 2012. Treatment outcomes were categorized according to the national TB guidelines.
  
  
  RESULTS
  A total of 535 cases of childhood TB were notified in 2012, representing 6.3% of the total TB cases notified in Lagos state in 2012. The prevalence of TB/HIV co-infection was 29%. The treatment success rate was 79.2% in TB/HIV-negative children compared with 73.4% in TB/HIV-positive children (p = 0.1268). Children <1 year had the worst treatment outcomes (p < 0.001).
  
  
  CONCLUSIONS
  There is a need to intensify effort at improving notification and treatment outcomes in children.
authors.affiliation: Department of Community Health and Primary Health Care, Lagos State University Teaching Hospital Lagos, Nigeria drolus_adejumo@yahoo.com.
authors.forename: Olusola Adedeji
authors.initials: OA
authors.lastname: Adejumo
authors.affiliation: Department of Community Medicine and Primary Care Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria.
authors.forename: Olusoji James
authors.initials: OJ
authors.lastname: Daniel
authors.affiliation: Department of Community Health and Primary Health Care, Lagos State University Teaching Hospital Lagos, Nigeria.
authors.forename: Bisola Ibironke
authors.initials: BI
authors.lastname: Adebayo
authors.affiliation: Department of Medical Laboratory Science, Babcock University, Ilisan -Remo, Ogun State, Nigeria.
authors.forename: Esther Ngozi
authors.initials: EN
authors.lastname: Adejumo
authors.affiliation: Centre for Research in Reproductive Health, Sagamu, Nigeria.
authors.forename: Ebunoluwa Olasumbo
authors.initials: EO
authors.lastname: Jaiyesimi
authors.affiliation: National TBL Control Programme, Abuja, FCT, Nigeria.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Akang
authors.affiliation: World Health Organization, Abuja, FCT, Nigeria.
authors.forename: Ayodele
authors.initials: A
authors.lastname: Awe
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D060085:Coinfection / Q000453:epidemiology; D018563:Disease Notification / Q000706:statistics & numerical data*; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D009549:Nigeria / Q000453:epidemiology; D011159:Population Surveillance; D015995:Prevalence; D012189:Retrospective Studies; D013183:Sputum / Q000382:microbiology; D016896:Treatment Outcome; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents
keywords: TB; childhood; treatment outcome