title: The Efficacy of Continuous Negative Pressure and Irrigation Treatment Inside the Wound by a Closed System in Reconstruction of All Layers of the Cranium Accompanying Infection and Cerebrospinal Fluid Leakage.
abstract: There have been many reports to date with respect to treatments on reconstruction of the cranium without accompanying infections following trauma and tumor resection. The morality is, however, high in patients observed with generation of cranial bone defect of all layers accompanying infection and cerebrospinal fluid leakage, and moreover, there are barely any reports on such cases because of the reconstruction thereof being very difficult. In this study, the authors were able to cure such 2 cases by carrying out continuous negative pressure and irrigation treatment inside the wound by a closed system following transplant of free latissimus dorsi muscle flap. This method is believed to be very effective for cranial bone defect of all layers accompanying infection and cerebrospinal fluid leakage, in which treatment was determined to be very difficult.
authors.affiliation: Department of Plastic and Reconstructive Surgery and Maxillofacial Surgery, Kurume University School of Medicine, Kurume-shi, Fukuoka, Japan.
authors.forename: Mai
authors.initials: M
authors.lastname: Oyama
authors.forename: Hideaki
authors.initials: H
authors.lastname: Rikimaru
authors.forename: Hisashi
authors.initials: H
authors.lastname: Migita
authors.forename: Kensuke
authors.initials: K
authors.lastname: Sakata
authors.forename: Kensuke
authors.initials: K
authors.lastname: Kiyokawa
mesh_terms: D000328:Adult; D065634:Cerebrospinal Fluid Leak / Q000628:therapy*; D003399:Craniotomy / Q000379:methods*; D003646:Debridement / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000637:transplantation*; D054843:Negative-Pressure Wound Therapy / Q000295:instrumentation / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods; D019651:Plastic Surgery Procedures / Q000379:methods*; D016038:Skin Transplantation / Q000379:methods; D013345:Subarachnoid Hemorrhage / Q000601:surgery; D013396:Suction / Q000295:instrumentation / Q000379:methods; D013530:Surgical Wound Infection / Q000628:therapy*; D013701:Temporal Bone / Q000601:surgery; D007507:Therapeutic Irrigation / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome