title: Clinical and Molecular Characterization of Invasive Heteroresistant Vancomycin-Intermediate Staphylococcus aureus Infections in Korean Hospitals.
abstract: Invasive heteroresistant vancomycin-intermediate Staphylococcus aureus (h-VISA) isolates were identified and characterized in 10 Korean hospitals from July 2009 to June 2011. The prevalence of h-VISA infections was 3.3% (42/1,289). Most (41/42) were health care-associated infections caused by strains belonging to sequence type 5. Cases of persistent bacteremia were frequent (17/42), and 30-day mortality was high (16/40).
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
authors.forename: Eu Suk
authors.initials: ES
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea.
authors.forename: In-Gyu
authors.initials: IG
authors.lastname: Bae
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
authors.forename: Jeong Eun
authors.initials: JE
authors.lastname: Cho
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
authors.forename: Yun Jung
authors.initials: YJ
authors.lastname: Choi
authors.affiliation: Division of Antimicrobial Resistance, Center for Infectious Diseases, Korea National Institute of Health, KCDC, Cheongju, South Korea.
authors.forename: Il-Hwan
authors.initials: IH
authors.lastname: Kim
authors.affiliation: Division of Antimicrobial Resistance, Center for Infectious Diseases, Korea National Institute of Health, KCDC, Cheongju, South Korea.
authors.forename: Gi-Su
authors.initials: GS
authors.lastname: Kang
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
authors.forename: Hye-yun
authors.initials: HY
authors.lastname: Sin
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
authors.forename: Kyoung-Ho
authors.initials: KH
authors.lastname: Song
authors.affiliation: Vaccine Bio Research Institute, The Catholic University of Korea, Seoul, South Korea.
authors.forename: Chulmin
authors.initials: C
authors.lastname: Park
authors.affiliation: Vaccine Bio Research Institute, The Catholic University of Korea, Seoul, South Korea Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
authors.forename: Dong-Gun
authors.identifier: http://orcid.org/0000-0003-4655-0641
authors.initials: DG
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.
authors.forename: Moonsuk
authors.initials: M
authors.lastname: Kim
authors.affiliation: Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, South Korea.
authors.forename: Kyoung Un
authors.initials: KU
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea hbkimmd@snu.ac.kr.
authors.forename: Hong Bin
authors.identifier: http://orcid.org/0000-0001-6262-372X
authors.initials: HB
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003428:Cross Infection; D005260:Female; D006761:Hospitals; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D056910:Republic of Korea / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics*; D020713:Vancomycin Resistance; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents