title: [Subcutaneous panniculitis-like T-cell lymphoma : Two case reports].
abstract: Histopathology, immunohistochemical, and molecular genetic findings revealed the diagnosis of subcutaneous panniculitis-like T-cell-lymphoma in two patients, aged 44 and 70 years. The clinical morphology of the lymphoma manifestations showed varied significantly. One patient presented with a singular erythematous nodule in the chin region. The other patient suffered from extended plate-like resistances and atrophy of the face, upper arms and left breast. Hemophagocytic syndrome was not present in either patient. Prognosis of subcutaneous panniculitis-like T-cell lymphoma without associated hemophagocytic syndrome is reported to be favorable. Radiotherapy of the singular lesion on the chin and systemic corticosteroids of the extended plaques induced complete remission in both patients.
authors.affiliation: Klinik für Dermatologie, Allergologie und Phlebologie, Klinikum Bremerhaven Reinkenheide, Postbrookstr. 103, 27574, Bremerhaven, Deutschland. gunnar.wagner@klinikum-bremerhaven.de.
authors.forename: G
authors.initials: G
authors.lastname: Wagner
authors.affiliation: Dermatohistologisches Labor, Lübeck, Deutschland.
authors.forename: Ch
authors.initials: Ch
authors.lastname: Rose
authors.affiliation: Klinik für Dermatologie, Allergologie und Phlebologie, Klinikum Bremerhaven Reinkenheide, Postbrookstr. 103, 27574, Bremerhaven, Deutschland.
authors.forename: V
authors.initials: V
authors.lastname: Meyer
authors.affiliation: Klinik für Dermatologie, Venerologie und Allergologie, Universitätsmedizin Mannheim, Medizinische Fakultät Mannheim, Ruprecht-Karls-Universität Heidelberg, Mannheim, Deutschland.|Hautklinik, Städtisches Klinikum Karlsruhe, Karlsruhe, Deutschland.
authors.forename: C-D
authors.initials: CD
authors.lastname: Klemke
authors.affiliation: Pathologisches Institut Bremerhaven, Bremerhaven, Deutschland.
authors.forename: W
authors.initials: W
authors.lastname: Back
authors.affiliation: Klinik für Dermatologie, Allergologie und Phlebologie, Klinikum Bremerhaven Reinkenheide, Postbrookstr. 103, 27574, Bremerhaven, Deutschland.
authors.forename: M M
authors.initials: MM
authors.lastname: Sachse
mesh_terms: D000328:Adult; D000368:Aged; D059248:Chemoradiotherapy / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000473:pathology* / Q000628:therapy*; D015434:Panniculitis / Q000473:pathology / Q000628:therapy; D011239:Prednisolone / Q000008:administration & dosage*; D012878:Skin Neoplasms / Q000473:pathology* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D011239:Prednisolone
keywords: Cutaneous γ-δ-T-cell lymphoma; Hemophagocytic syndrome; Prednisolone; Radiotherapy; Remission