title: Head Motion and Correction Methods in Resting-state Functional MRI.
abstract: Resting-state functional magnetic resonance imaging (RS-fMRI) is used to investigate brain functional connectivity at rest. However, noise from human physiological motion is an unresolved problem associated with this technique. Following the unexpected previous result that group differences in head motion between control and patient groups caused group differences in the resting-state network with RS-fMRI, we reviewed the effects of human physiological noise caused by subject motion, especially motion of the head, on functional connectivity at rest detected with RS-fMRI. The aim of the present study was to review head motion artifact with RS-fMRI, individual and patient population differences in head motion, and correction methods for head motion artifact with RS-fMRI. Numerous reports have described new methods [e.g., scrubbing, regional displacement interaction (RDI)] for motion correction on RS-fMRI, many of which have been successful in reducing this negative influence. However, the influence of head motion could not be entirely excluded by any of these published techniques. Therefore, in performing RS-fMRI studies, head motion of the participants should be quantified with measurement technique (e.g., framewise displacement). Development of a more effective correction method would improve the accuracy of RS-fMRI analysis.
authors.affiliation: School of Allied Health Sciences, Kitasato University.
authors.forename: Masami
authors.initials: M
authors.lastname: Goto
authors.forename: Osamu
authors.initials: O
authors.lastname: Abe
authors.forename: Tosiaki
authors.initials: T
authors.lastname: Miyati
authors.forename: Hidenori
authors.initials: H
authors.lastname: Yamasue
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Gomi
authors.forename: Tohoru
authors.initials: T
authors.lastname: Takeda
mesh_terms: D016477:Artifacts; D001931:Brain Mapping / Q000379:methods*; D006257:Head / Q000000981:diagnostic imaging*; D019416:Head Movements / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*