title: Resveratrol and Omega-3 Fatty Acid: Its Implications in Cardiovascular Diseases.
abstract: The present review aims at summarizing the major therapeutic roles of resveratrol and omega-3 fatty acids (O3FAs) along with their related pathways. This article reviews some of the key studies involving the health benefits of resveratrol and O3FAs. Oxidative stress has been considered as one of the most important pathophysiological factors associated with various cardiovascular disease conditions. Resveratrol, with the potent antioxidant and free radical scavenging properties, has been proven to be a significantly protective compound in restoring the normal cardiac health. A plethora of research also demonstrated the reduction of the risk of coronary heart disease, hypertension, and stroke, and their complications by O3FAs derived from fish and fish oils. This review describes the potential cardioprotective role of resveratrol and O3FAs in ameliorating the endoplasmic reticulum stress.
authors.affiliation: Department of Pharmaceutical Sciences, Dibrugarh University , Assam , India.
authors.forename: Bibhuti Bhusan
authors.initials: BB
authors.lastname: Kakoti
authors.affiliation: College of Pharmacy, University of South Florida , Tampa, FL , USA.
authors.forename: Diana G
authors.initials: DG
authors.lastname: Hernandez-Ontiveros
authors.affiliation: Department of Pharmaceutical Sciences, Dibrugarh University , Assam , India.
authors.forename: Manjir Sarma
authors.initials: MS
authors.lastname: Kataki
authors.affiliation: College of Pharmacy, University of South Florida , Tampa, FL , USA.
authors.forename: Kajri
authors.initials: K
authors.lastname: Shah
authors.affiliation: College of Pharmacy, University of South Florida , Tampa, FL , USA.
authors.forename: Yashwant
authors.initials: Y
authors.lastname: Pathak
authors.affiliation: College of Pharmacy, University of South Florida , Tampa, FL , USA.
authors.forename: Siva Kumar
authors.initials: SK
authors.lastname: Panguluri
keywords: cardiovascular diseases; coronary artery diseases; endoplasmic reticulum stress; omega-3 fatty acid; oxidative stress; resveratrol