title: Beneficial health characteristics of native and hydrolysed konjac (Amorphophallus konjac) glucomannan.
abstract: The impact of ingesting glucomannans on health is not limited to colonic-focused fermentation into short-chain fatty acids (SCFAs), which might have some local health benefits; it also helps in treating disease states and enhancing the body's immune system, both within the gut and in/on other parts of the body. The local and systemic roles of hydrolysed glucomannans, especially konjac glucomannans, in the mouth, oesophagus, stomach, small intestine, large intestine, gut-associated lymphoid tissue (GALT), skin and vagina, are highlighted. Therapeutic applications are discussed. © 2015 Society of Chemical Industry.
authors.affiliation: Glycologic Limited, Glasgow G4 0BA, UK.
authors.forename: Richard F
authors.initials: RF
authors.lastname: Tester
authors.affiliation: Glycologic Limited, Glasgow G4 0BA, UK.
authors.forename: Farage H
authors.initials: FH
authors.lastname: Al-Ghazzewi
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development; D003106:Colon / Q000378:metabolism; D004043:Dietary Fiber / Q000008:administration & dosage*; D005232:Fatty Acids, Volatile / Q000378:metabolism; D005260:Female; D005285:Fermentation; D006293:Health Promotion; D006801:Humans; D006868:Hydrolysis; D007107:Immune System / Q000187:drug effects; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy; D007422:Intestines / Q000187:drug effects / Q000382:microbiology; D008221:Lymphoid Tissue / Q000187:drug effects; D008351:Mannans / Q000008:administration & dosage* / Q000737:chemistry; D009055:Mouth / Q000382:microbiology; D019936:Probiotics; D012867:Skin / Q000187:drug effects; D014621:Vagina / Q000187:drug effects
chemical_list: D004043:Dietary Fiber; D005232:Fatty Acids, Volatile; D008351:Mannans; C022901:(1-6)-alpha-glucomannan
keywords: GALT; gut; hydrolysed glucomannan; skin; systemic; vagina