title: Deterministic model for the transport of energetic particles: Application in the electron radiotherapy.
abstract: A new deterministic method for calculating the dose distribution in the electron radiotherapy field is presented. The aim of this work was to validate our model by comparing it with the Monte Carlo simulation toolkit, GEANT4. A comparison of the longitudinal and transverse dose deposition profiles and electron distributions in homogeneous water phantoms showed a good accuracy of our model for electron transport, while reducing the calculation time by a factor of 50. Although the Bremsstrahlung effect is not yet implemented in our model, we propose here a method that solves the Boltzmann kinetic equation and provides a viable and efficient alternative to the expensive Monte Carlo modeling.
authors.affiliation: CELIA Centre des Lasers Intenses et Applications, University of Bordeaux CNRS CEA, Talence F-33400, France; Department of Radiotherapy, Institut Bergonie, Comprehensive Cancer Center, Bordeaux F-33076, France. Electronic address: j.caron@celia-u.bordeaux1.fr.
authors.forename: J
authors.initials: J
authors.lastname: Caron
authors.affiliation: CELIA Centre des Lasers Intenses et Applications, University of Bordeaux CNRS CEA, Talence F-33400, France.
authors.forename: J-L
authors.initials: JL
authors.lastname: Feugeas
authors.affiliation: CELIA Centre des Lasers Intenses et Applications, University of Bordeaux CNRS CEA, Talence F-33400, France.
authors.forename: B
authors.initials: B
authors.lastname: Dubroca
authors.affiliation: Department of Radiotherapy, Institut Bergonie, Comprehensive Cancer Center, Bordeaux F-33076, France.
authors.forename: G
authors.initials: G
authors.lastname: Kantor
authors.affiliation: Department of Radiotherapy, Centre Antoine Lacassagne, Comprehensive Cancer Center, Nice F-06000, France.
authors.forename: C
authors.initials: C
authors.lastname: Dejean
authors.affiliation: CELIA Centre des Lasers Intenses et Applications, University of Bordeaux CNRS CEA, Talence F-33400, France.
authors.forename: G
authors.initials: G
authors.lastname: Birindelli
authors.affiliation: CELIA Centre des Lasers Intenses et Applications, University of Bordeaux CNRS CEA, Talence F-33400, France.
authors.forename: T
authors.initials: T
authors.lastname: Pichard
authors.affiliation: CELIA Centre des Lasers Intenses et Applications, University of Bordeaux CNRS CEA, Talence F-33400, France.
authors.forename: P
authors.initials: P
authors.lastname: Nicolaï
authors.affiliation: CELIA Centre des Lasers Intenses et Applications, University of Bordeaux CNRS CEA, Talence F-33400, France.
authors.forename: E
authors.initials: E
authors.lastname: d'Humières
authors.affiliation: Department of Mathematics, Center for Engineering Computational Science, RWTH Aachen University, Aachen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Frank
authors.affiliation: CELIA Centre des Lasers Intenses et Applications, University of Bordeaux CNRS CEA, Talence F-33400, France.
authors.forename: V
authors.initials: V
authors.lastname: Tikhonchuk
mesh_terms: D004583:Electrons / Q000627:therapeutic use*; D008962:Models, Theoretical; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D011881:Radiotherapy, Computer-Assisted; D014867:Water
chemical_list: D014867:Water
keywords: Deterministic algorithm; Electron dosimetry; Monte Carlo algorithm; Radiotherapy treatment planning system