title: [Peri-operation treatment for patients with hemophilia A in children with intracranial malignant tumor: a report of 2 cases].
abstract: Hemophilia A is aninherited bleeding disorder, lack of coagulation factor VIII (FVIII), and if combined with intracranial malignant tumor, the operation risk is very high. Department of Pediatric Surgery in Peking University First Hospital used coagulation factor replacement therapy, succeeded in the operation of 2 cases of intracranial malignant tumor with hemophilia A in children, with no abnormal bleeding events. The establishment of the multi subject cooperation group before operation, good preoperative preparation, enough alternative factors, and close postoperative monitoring, are the key to the successful treatment.
authors.affiliation: Department of Pediatric Surgery, Peking University First Hospital, Beijing 100034, China.
authors.forename: Yang-xu
authors.initials: YX
authors.lastname: Gao
authors.affiliation: Department of Pediatric Surgery, Peking University First Hospital, Beijing 100034, China.
authors.forename: Hong-ru
authors.initials: HR
authors.lastname: Zhang
authors.affiliation: Department of Pediatric Surgery, Peking University First Hospital, Beijing 100034, China.
authors.forename: Li-xue
authors.initials: LX
authors.lastname: Shen
authors.affiliation: Department of Pediatric Surgery, Peking University First Hospital, Beijing 100034, China.
authors.forename: Bao-fu
authors.initials: BF
authors.lastname: Liu
authors.affiliation: Department of Pediatric Surgery, Peking University First Hospital, Beijing 100034, China.
authors.forename: Hong-xin
authors.initials: HX
authors.lastname: Yao
mesh_terms: D001932:Brain Neoplasms / Q000601:surgery*; D002648:Child; D006467:Hemophilia A / Q000150:complications*; D006470:Hemorrhage / Q000517:prevention & control*; D006801:Humans; D019990:Perioperative Care