title: Characterization of Field Effect Transistor Biosensors Fabricated Using Layer-by-Layer Nanoassembly Process.
abstract: In order to avoid the fabrication complexity involved with a single carbon nanotube (CNT) based immunosensor, herein we report an FET based biosensor, in which the channel is made out of Carbon Nanotube Thin Film (CNTF). The CNTF channel between the source and drain electrodes is assembled using a combination of photolithography and electrostatic layer-by-layer self-assembly (LbL). The fabricated device behaves like a p-type transistor. The bio-affinity interaction between Protein A and rabbit Immunoglobulin G (IgG) is used to model the immunosensing, and our initial results show the device is capable of detecting IgG concentrations as low as 1 pg/mL.
authors.forename: Pushparaj
authors.initials: P
authors.lastname: Pathak
authors.forename: Long
authors.initials: L
authors.lastname: Que
mesh_terms: D000818:Animals; D015374:Biosensing Techniques; D004566:Electrodes; D007074:Immunoglobulin G / Q000737:chemistry; D037742:Nanotubes, Carbon / Q000737:chemistry*; D011817:Rabbits; D013205:Staphylococcal Protein A / Q000737:chemistry; D055672:Static Electricity
chemical_list: D007074:Immunoglobulin G; D037742:Nanotubes, Carbon; D013205:Staphylococcal Protein A