title: Alcohol and HIV Effects on the Immune System.
abstract: HIV disease and alcohol independently influence the human immune system, so it stands to reason that, together, their influence may be additive. Here, we review the evidence that alcohol can exacerbate HIV's influence on the immune system, thereby affecting disease progression and transmission. We focus particularly on alcohol's effect on the mucosal immune system in the tissues of the gastrointestinal tract, the genital tract and the lungs, all of which play a role in transmission and progression of HIV disease.
authors.affiliation: Tulane National Primate Research Center, Covington, Louisiana.
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Bagby
authors.affiliation: Tulane National Primate Research Center, Covington, Louisiana.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Amedee
authors.affiliation: Tulane National Primate Research Center, Covington, Louisiana.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Siggins
authors.affiliation: Tulane National Primate Research Center, Covington, Louisiana.
authors.forename: Patricia E
authors.initials: PE
authors.lastname: Molina
authors.affiliation: Tulane National Primate Research Center, Covington, Louisiana.
authors.forename: Steve
authors.initials: S
authors.lastname: Nelson
authors.affiliation: Tulane National Primate Research Center, Covington, Louisiana.
authors.forename: Ronald S
authors.initials: RS
authors.lastname: Veazey
mesh_terms: D000428:Alcohol Drinking / Q000276:immunology*; D000437:Alcoholism / Q000150:complications / Q000276:immunology*; D018450:Disease Progression; D041981:Gastrointestinal Tract / Q000276:immunology*; D015658:HIV Infections / Q000150:complications / Q000276:immunology* / Q000635:transmission; D006801:Humans; D018928:Immunity, Mucosal / Q000276:immunology*