title: F-BAR/EFC Domain Proteins: Some Assembly Required.
abstract: Polymeric spirals of crescent-shaped BAR-domain superfamily proteins are touted to girdle eukaryotic phospholipid bilayers into narrow tubules for trafficking and membrane remodeling events. But McDonald et al. (2015) in this issue of Developmental Cell question whether this broadly held view and conceptually appealing mechanism for membrane sculpting is really overhyped.
authors.affiliation: Department of Cell Biology, University of Pittsburgh School of Medicine, 3500 Terrace Street, Pittsburgh, PA 15261, USA. Electronic address: traub@pitt.edu.
authors.forename: Linton M
authors.initials: LM
authors.lastname: Traub
mesh_terms: D002352:Carrier Proteins / Q000378:metabolism*; D018797:Cell Cycle Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism*; D048749:Cytokinesis / Q000502:physiology*; D006801:Humans; D055503:Protein Multimerization; D012568:Schizosaccharomyces / Q000378:metabolism*; D029702:Schizosaccharomyces pombe Proteins / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D029702:Schizosaccharomyces pombe Proteins