title: [The lung function status in patients with severe acute respiratory syndrome after ten years of convalescence in Tianjin].
abstract: OBJECTIVE
  To evaluate the lung function in patients with severe acute respiratory syndrome (SARS) 10 years after recovery and the influencing factors.
  
  
  METHODS
  Pulmonary function tests were performed in 25 convalescent patients who had a diagnosis of SARS in 2003. Total lung volume, residual capacity, vital capacity, forced vital capacity (FVC), FEV1, FEV1/FVC and lung carbon monoxide diffusion (DLCO) were measured, and compared with the values obtained immediately after recovery in 2003. Of the 25 cases, 3 were males and 22 were females, aging 31-69 years [average (45.8 ± 12.2)]. Twenty-five healthy adults (6 males, 19 females), aged 31-62 years [average (42.3 ± 11.9) years], were recruited as controls.
  
  
  RESULTS
  Of the 25 cases, 2 showed simple diffusion dysfunction, 2 simple restrictive ventilatory dysfunction, 11 combined diffusion and restrictive ventilatory dysfunction, and 1 combined diffusion and obstructive ventilatory dysfunction. The remaining 10 cases showed normal lung function. There were no statistical differences in the pulmonary function measurements as compared with those measured 10 years ago, including DLCO (73 ± 12)% vs (72 ± 15)% (P>0.05), FEV1/FVC (83 ± 11)% vs (85 ± 7)%, (P>0.05), FEV1 (88 ± 7)% vs (86 ± 14)% (P>0.05), FVC (87 ± 21)% vs (87 ± 17)% (P>0.05), and RV (100 ± 17)% vs (78 ± 3 0)% (P>0.05). The lung functions of the patients showed no significant difference as compared with those obtained from the healthy controls.
  
  
  CONCLUSIONS
  The pulmonary functions of SARS patents largely returned to normal after 10 years of convalescence, and the lung function damage was characterized by diffusing and restrictive ventilatory dysfunctions.
authors.affiliation: Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China; Email: 13302031999@126.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Sun
authors.affiliation: Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
authors.forename: Zhihang
authors.initials: Z
authors.lastname: Xing
authors.affiliation: Department of Respiratory Medicine, Tianjin Haihe Hospital, Tianjin 300350, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Yu
mesh_terms: D000328:Adult; D000368:Aged; D002248:Carbon Monoxide; D003289:Convalescence; D005260:Female; D006801:Humans; D008168:Lung; D008297:Male; D008875:Middle Aged; D012129:Respiratory Function Tests; D045169:Severe Acute Respiratory Syndrome; D014797:Vital Capacity
chemical_list: D002248:Carbon Monoxide