title: Glomerulocystic Kidney Disease and Hepatoblastoma in an Infant: A Rare Presentation.
abstract: Glomerulocystic kidney disease (GCKD) is a rare condition comprising heritable and non-heritable types [Oh et al.: Nephron 1986;43:299-302]. Hepatoblastoma is a sporadically occurring tumor of embryonal origin that is associated with overgrowth syndrome and renal cysts. A concurrent presentation of GCKD with hepatoblastoma was first described in 1989 [Rao et al.: Jpn J Surg 1989;19:583-585]. We report the simultaneous presentation of hepatoblastoma and GCKD in a 5-month-old child and explore the probability of insulin-like growth factors, insulin-like growth factor-binding protein and Beckwith-Wiedemann gene mutation as a putative cause.
authors.affiliation: Miller Children's and Women's Hospital, Long Beach, Calif., USA.
authors.forename: Rumina
authors.initials: R
authors.lastname: Zaman
authors.affiliation: Drexler University, Philadelphia, Pa., USA.
authors.forename: Alec
authors.initials: A
authors.lastname: Maggi
authors.affiliation: American University of Antigua, St. John's, Antigua and Barbuda.
authors.forename: Sudeep K
authors.initials: SK
authors.lastname: Rajpoot
authors.affiliation: Miller Children's and Women's Hospital, Long Beach, Calif., USA.
authors.forename: Divya-Devi
authors.initials: DD
authors.lastname: Joshi
keywords: Beckwith-Wiedemann syndrome; Glomerulocystic kidney disease; Hepatoblastoma; Hepatocyte growth factor; Insulin-like growth factors