title: Reproducibility and conflicts in immune epitope data.
abstract: The Immune Epitope Database is uniquely positioned to assess the body of research related to immune epitopes, we have manually curated all such published data. Thus, we are able to make observations on the state of these fields of research, as well as aggregate the individual data points to present a clearer picture of the immune response to specific antigens in all studied hosts. Additionally, we are able to identify where conflicts in the literature exist and where publications fall short in terms of identifiable methods and in reproducibility. Here we present guidelines to improve the quality of immune epitope data, which will benefit journals and researchers alike.
authors.affiliation: Division of Vaccine Discovery, La Jolla Institute for Allergy & Immunology, La Jolla, CA, USA.
authors.forename: Randi
authors.identifier: http://orcid.org/0000-0001-8957-7612
authors.initials: R
authors.lastname: Vita
authors.affiliation: Ontology Development Group, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Nicole
authors.initials: N
authors.lastname: Vasilevsky
authors.affiliation: Neuroscience Information Framework, University of California, San Diego, San Diego, CA, USA.
authors.forename: Anita
authors.initials: A
authors.lastname: Bandrowski
authors.affiliation: Ontology Development Group, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Melissa
authors.initials: M
authors.lastname: Haendel
authors.affiliation: Division of Vaccine Discovery, La Jolla Institute for Allergy & Immunology, La Jolla, CA, USA.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Sette
authors.affiliation: Division of Vaccine Discovery, La Jolla Institute for Allergy & Immunology, La Jolla, CA, USA.
authors.forename: Bjoern
authors.initials: B
authors.lastname: Peters
mesh_terms: D000486:Allergy and Immunology / Q000592:standards*; D030562:Databases, Protein / Q000592:standards*; D000939:Epitopes / Q000276:immunology*; D006801:Humans; D015203:Reproducibility of Results
chemical_list: D000939:Epitopes
keywords: Immune Epitope Database; database; immune epitope; reproducibility