title: Variables associated with health-related quality of life in a Brazilian sample of patients from a tertiary outpatient clinic for depression and anxiety disorders.
abstract: BACKGROUND
  Health-related quality of life (HRQOL) assessment tools have been broadly used in the medical context. These tools are used to measure the subjective impact of the disease on patients. The objective of this study was to evaluate the variables associated with HRQOL in a Brazilian sample of patients followed up in a tertiary outpatient clinic for depression and anxiety disorders.
  
  
  METHODS
  Cross-sectional study. Independent variables were those included in a sociodemographic questionnaire and the Hospital Anxiety and Depression Scale (HADS) scores. Dependent variables were those included in the short version of the World Health Organization Quality of Life (WHOQOL-BREF) and the scores for its subdomains (overall quality of life and general health, physical health, psychological health, social relationships, and environment). A multiple linear regression analysis was used to find the variables independently associated with each outcome.
  
  
  RESULTS
  Seventy-five adult patients were evaluated. After multiple linear regression analysis, the HADS scores were associated with all outcomes, except social relationships (p = 0.08). Female gender was associated with poor total scores, as well as psychological health and environment. Unemployment was associated with poor physical health.
  
  
  CONCLUSIONS
  Identifying the factors associated with HRQOL and recognizing that depression and anxiety are major factors are essential to improve the care of patients.
authors.affiliation: Instituto de Psiquiatria de Santa Catarina, São José, SC, Brazil.
authors.forename: Bianca
authors.initials: B
authors.lastname: Schwab
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
authors.forename: Heloisa Silveira
authors.initials: HS
authors.lastname: Daniel
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
authors.forename: Carine
authors.initials: C
authors.lastname: Lutkemeyer
authors.affiliation: Prefeitura de São José, São José, SC, Brazil.
authors.forename: João Arthur Lange Lins
authors.initials: JA
authors.lastname: Neves
authors.affiliation: Instituto de Psiquiatria de Santa Catarina, São José, SC, Brazil.
authors.forename: Louise Nassif
authors.initials: LN
authors.lastname: Zilli
authors.affiliation: IPQ, São José, SC, Brazil.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Guarnieri
authors.affiliation: IPQ, São José, SC, Brazil.
authors.forename: Alexandre Paim
authors.initials: AP
authors.lastname: Diaz
authors.affiliation: UFSC, Florianópolis, SC, Brazil.
authors.forename: Ana Maria Maykot Prates
authors.initials: AM
authors.lastname: Michels
mesh_terms: D000328:Adult; D000554:Ambulatory Care Facilities; D001008:Anxiety Disorders / Q000453:epidemiology* / Q000523:psychology*; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000453:epidemiology* / Q000523:psychology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D010045:Outpatients / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012737:Sex Factors; D012959:Socioeconomic Factors; D062606:Tertiary Care Centers