title: [Invasive neuromodulation in the treatment of drug-resistant epilepsies].
abstract: Neuromodulation is one of the most developing new disciplines of medical science, which examines how electrical, chemical and mechanical interventions can modulate or change the functioning of the central and peripheral nervous system. Neuromodulation is a reversible form of therapy which uses electrical or mechanical stimulation or centrally-delivered drugs to modulate the abnormal function of the central nervous system in pain, spasticity, epilepsy, movement and psychiatric disorders, and certain cardiac, incontinency, visual and auditory diseases. Neuromodulation therapy has two major branches. Non-invasive neuromodulation includes transcranial magnetic simulation, direct current stimulation and transcutaneous electric nerve stimulation. Invasive neuromodulation includes deep brain stimulation, cortical stimulation, spinal cord stimulation, peripheral nerve stimulation, sacral nerve simulation, and subcutan stimulation. In this article the authors overview the apparently available neural interface technologies in epilepsy surgery.
authors.affiliation: Funkcionális Idegsebészeti Osztály és Neuromodulációs Központ, Országos Klinikai Idegtudományi Intézet Budapest, Amerikai út 57., 1145.
authors.forename: Loránd
authors.initials: L
authors.lastname: Erőss
authors.affiliation: Funkcionális Idegsebészeti Osztály és Neuromodulációs Központ, Országos Klinikai Idegtudományi Intézet Budapest, Amerikai út 57., 1145.
authors.forename: László
authors.initials: L
authors.lastname: Entz
authors.affiliation: Epilepszia Centrum, Neurológiai Osztály, Országos Klinikai Idegtudományi Intézet Budapest.
authors.forename: Dániel
authors.initials: D
authors.lastname: Fabó
mesh_terms: D002540:Cerebral Cortex; D046690:Deep Brain Stimulation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D000069279:Drug Resistant Epilepsy / Q000503:physiopathology / Q000628:therapy*; D019317:Evidence-Based Medicine; D006801:Humans; D010525:Peripheral Nerves; D016032:Randomized Controlled Trials as Topic; D013116:Spinal Cord; D013788:Thalamus; D065908:Transcranial Direct Current Stimulation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D004561:Transcutaneous Electric Nerve Stimulation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D055536:Vagus Nerve Stimulation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods
keywords: deep brain stimulation; epilepsy; epilepszia; gerincvelői ingerlés; mély agyi stimuláció; neuromodulation; neuromoduláció; responsive neurostimulation; reszponzív neurostimuláció; spinal cord stimulation; vagal nerve stimulation; vagusideg-stimuláció