title: Development and testing of hyperpolarized (13)C MR calibrationless parallel imaging.
abstract: A calibrationless parallel imaging technique developed previously for (1)H MRI was modified and tested for hyperpolarized (13)C MRI for applications requiring large FOV and high spatial resolution. The technique was demonstrated with both retrospective and prospective under-sampled data acquired in phantom and in vivo rat studies. A 2-fold acceleration was achieved using a 2D symmetric EPI readout equipped with random blips on the phase encode dimension. Reconstructed images showed excellent qualitative agreement with fully sampled data. Further acceleration can be achieved using acquisition schemes that incorporate multi-dimensional under-sampling.
authors.affiliation: Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.
authors.forename: Yesu
authors.initials: Y
authors.lastname: Feng
authors.affiliation: Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.
authors.forename: Jeremy W
authors.initials: JW
authors.lastname: Gordon
authors.affiliation: Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Shin
authors.affiliation: Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.
authors.forename: Cornelius
authors.initials: C
authors.lastname: von Morze
authors.affiliation: Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Lustig
authors.affiliation: Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.
authors.forename: Peder E Z
authors.initials: PEZ
authors.lastname: Larson
authors.affiliation: Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Ohliger
authors.affiliation: Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA.
authors.forename: Lucas
authors.initials: L
authors.lastname: Carvajal
authors.affiliation: GE Healthcare, Fremont, CA, USA.
authors.forename: James
authors.initials: J
authors.lastname: Tropp
authors.affiliation: Department of Electrical Engineering, Stanford University, Stanford, CA, USA.
authors.forename: John M
authors.initials: JM
authors.lastname: Pauly
authors.affiliation: Department of Radiology and Biomedical Imaging, UCSF, San Francisco, CA, USA. Electronic address: dan.vigneron@ucsf.edu.
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Vigneron
mesh_terms: D020001:1-Butanol / Q000378:metabolism; D000465:Algorithms; D000818:Animals; D002247:Carbon Isotopes; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D011446:Prospective Studies; D019289:Pyruvic Acid / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D012984:Software
chemical_list: D002247:Carbon Isotopes; D019289:Pyruvic Acid; D020001:1-Butanol
keywords: Carbon-13; Hyperpolarization; Parallel imaging