title: Study of interaction between water-soluble collagen and carboxymethyl cellulose in neutral aqueous solution.
abstract: The interactions of succinylated collagen (SC) and carboxymethyl cellulose (CMC) in neutral solutions (pH ∼ 6.9) were investigated, which could provide information for the fields of tissue engineering and cosmetics. According to the results from viscometric measurements, the SC and CMC molecules were possibly compatible as CMC ≤ 50%. Ultrasensitive microcalorimetry reflected the increase in the values of transition temperature (Tm) and heat capacity change (ΔCp) as CMC ≤ 50%, while both of them decreased as the CMC content further increased. Two-dimensional Fourier transform infrared spectroscopy analysis confirmed the hydrogen bonding and electrostatic interactions between SC and CMC, and the hydrogen bonding interaction played a key role as CMC ≤ 50%, while electrostatic interaction became predominant as more CMC was added. Atomic force morphology revealed the changes in the aggregation of SC induced by the addition of CMC.
authors.affiliation: College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350002, PR China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.affiliation: College of Ecological Environment and Urban Construction, Fujian University of Technology, Fuzhou 350108, PR China.
authors.forename: Cuicui
authors.initials: C
authors.lastname: Ding
authors.affiliation: College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350002, PR China.
authors.forename: Junhui
authors.initials: J
authors.lastname: Yang
authors.affiliation: College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350002, PR China.
authors.forename: Shan
authors.initials: S
authors.lastname: Lin
authors.affiliation: College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350002, PR China.
authors.forename: Lihui
authors.initials: L
authors.lastname: Chen
authors.affiliation: College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350002, PR China. Electronic address: fafuhll@163.com.
authors.forename: Liulian
authors.initials: L
authors.lastname: Huang
mesh_terms: D002266:Carboxymethylcellulose Sodium / Q000737:chemistry*; D003094:Collagen / Q000737:chemistry*; D055550:Protein Stability; D012995:Solubility; D055672:Static Electricity; D013386:Succinates / Q000737:chemistry; D044366:Transition Temperature; D014783:Viscosity
chemical_list: D013386:Succinates; D003094:Collagen; D002266:Carboxymethylcellulose Sodium
keywords: Aggregation; Carboxymethyl cellulose; Interaction; Succinylated collagen; Thermal stability; Two-dimensional FTIR