title: [Clinical research of sudden sensorineural hearing loss due to inner-ear hemorrhage].
abstract: OBJECTIVE
  This study addresses the characters of magnetic resonance imaging (MRI) and clinical features, and curative effects in the screening of SSNHL due to inner-ear hemorrhage.
  
  
  METHODS
  MRI and relevant audiometric test were given to 160 patients with SSNHL, who were hospitalized in the First Affiliated Hospital of Sun Yat-sen University from January 2011 to April 2013. The clinical features and curative effects of patients with high signals in the labyrinth on MRI were analyzed.
  
  
  RESULTS
  MRI abnormities were found in 22 (13.8%) of the patients. Specifically, eight cases were considered for inner-ear hemorrhage. For the eight inner-ear hemorrhage cases, clinical features included the sudden onset of complete hearing loss, which worsened within several hours. Pure tone audiometry indicated profound sensorineural deafness. The prevalence of inner-ear hemorrhage was 5% in SSNHL cases and 18.6% in cases of profound sensorineural. MRI showed high signal intensity in the cochlear, semicircular canals or vestibule on unenhanced T1-weighted and fluid-attenuated inversion recovery images. The high signal intensity in the inner ear gradually degraded in six months. There was no improvement in hearing for the patients with inner-ear hemorrhage following symptomatic therapy.
  
  
  CONCLUSIONS
  SSNHL due to inner-ear hemorrhage is characterized by profound sensorineural deafness in all frequencies, and high signal intensity for the hemorrhagic inner ear on T1-weighted MRI, with poor prognosis.
authors.affiliation: Department of Otorhinolaryngology, the First Affiliated Hospital, Sun Yat-sen University and Institute of Otorhinolaryngology, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Wu
authors.forename: Liang
authors.initials: L
authors.lastname: Sun
authors.forename: Kaitian
authors.initials: K
authors.lastname: Chen
authors.forename: Zhiyun
authors.initials: Z
authors.lastname: Yang
authors.forename: Xihui
authors.initials: X
authors.lastname: Chen
authors.affiliation: Email: hyjiangwu@163.com.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Jiang
mesh_terms: D001301:Audiometry, Pure-Tone; D003051:Cochlea / Q000503:physiopathology; D003638:Deafness / Q000209:etiology; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D003639:Hearing Loss, Sudden / Q000209:etiology*; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D012665:Semicircular Canals / Q000503:physiopathology; D014722:Vestibule, Labyrinth / Q000503:physiopathology