title: FDG-PET/CT appearance of injected silicone particles (VOX Implants®) in head and neck tissues.
abstract: OBJECTIVE
  In head and neck surgery, Positron Emission Tomography/Computed Tomography imaging (FDG-PET/CT) is often used to identify primary tumor site in patients with unknown primary carcinoma, to predict response after chemoradiotherapy and in some cases, to detect recurrence. To rehabilitate swallowing after surgery in patients with persistent dysphagia, an injectable suspension of silicone (VOX® Implants) can be used to reduce the gaps in the neoglottis. The purpose of this report is to document the PET appearance of PDMS in a series of 3 patients who underwent partial laryngectomy with subsequent VOX® Implants injection.
  
  
  METHODS
  a retrospective chart and imaging review was performed at our institution. Three patients were identified and included in the study. Appearance of PDMS at PET was described and discussed.
  
  
  RESULTS
  An increased uptake of 2-fluoro-2-deoxy-d-glucose (FDG) was noticed at PET in all patients.
  
  
  CONCLUSIONS
  the increased uptake was possibly due to active inflammatory reactions that are necessary for tissue integration of textured silicone particles.
authors.affiliation: . alessiapiccinini@hotmail.com.
authors.forename: Alessia
authors.initials: A
authors.lastname: Piccinini
authors.forename: Matteo
authors.initials: M
authors.lastname: Alicandri-Ciufelli
authors.forename: Angelo
authors.initials: A
authors.lastname: Ghidini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Bergamini
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Vincenti
authors.forename: Andrea
authors.initials: A
authors.lastname: Bacciu
authors.forename: Teore
authors.initials: T
authors.lastname: Ferri
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Cesinaro
authors.forename: Livio
authors.initials: L
authors.lastname: Presutti
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000601:surgery; D003680:Deglutition Disorders / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy*; D004129:Dimethylpolysiloxanes / Q000627:therapeutic use*; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007825:Laryngectomy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D004129:Dimethylpolysiloxanes; C013830:baysilon