title: Age peculiarities of reproductive morbidity in female participants of the ChNPP accident consequences clean up (according to the figures from SRU, 1988-2012 survey period).
abstract: OBJECTIVE
  to assess and estimate the peculiarities of genital system morbidity in female participants of the ChNPP accident clean up works in 1986-1987 depending on age at exposure to ionizing radiation and time since exposure.
  
  
  METHODS
  Data on the Chernobyl disaster survivors received from the State Registry of Ukraine are out line in the paper. Review of the level and pattern of genital system morbidity was carried out for the 17,237 female participants of the ChNPP accident clean up works in 1986-1987 depending on time under risk upon radiation expo sure and reproductive age at exposure. Survey period lasted since 1988 till 2012. Assessment of morbidity level, con fidential intervals, and statistical significance was carried out using the trial version of ОpenEpiversion 2.3.1. soft ware. Statistical significance was also rated using the z score and t criterion.
  
  
  RESULTS
  The results of this cohort epidemiological study showed that there are some peculiarities of natural course of the female genital system disease depending on reproductive age at exposure and time under risk upon radiation impact. Comparative statistical review of the level and pattern of genital system morbidity at different times within a survey period.
  
  
  CONCLUSIONS
  Exposure to ionizing radiation in the childbearing age (18-45 years old) can be a risk factor of elevated incidence of uterine leiomyoma, benign mammary dysplasia (i.e. benign breast disease), and salpingo oophoritis. It is far to assume that uterine and mammary tissues are more sensitive to impact of ionizing radiation in females of the childbearing age vs. in persons exposed in pre menopause or menopause.
authors.affiliation: State Institution National Research Center for Radiation Medicine of National Academy of MedicalSciences of Ukraine, Melnikova str., 53, Kyiv, 04050, Ukraine.
authors.forename: I O
authors.initials: IO
authors.lastname: Mayevska
authors.affiliation: State Institution National Research Center for Radiation Medicine of National Academy of MedicalSciences of Ukraine, Melnikova str., 53, Kyiv, 04050, Ukraine.
authors.forename: V O
authors.initials: VO
authors.lastname: Buzunov
keywords: female participants of the ChNPP accident clean up; genital system disease; ionizing radiation