title: Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis.
abstract: OBJECTIVE
  To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC).
  
  
  METHODS
  A retrospective investigation of patients with TLE-HS was conducted in a tertiary center.
  
  
  RESULTS
  Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163).
  
  
  CONCLUSIONS
  Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients.
authors.affiliation: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Lucas Crociati
authors.initials: LC
authors.lastname: Meguins
authors.affiliation: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Rodrigo Antônio Rocha da Cruz
authors.initials: RA
authors.lastname: Adry
authors.affiliation: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Sebastião Carlos da
authors.initials: SC
authors.lastname: Silva Júnior
authors.affiliation: Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, SE, Brazil.
authors.forename: Carlos Umberto
authors.initials: CU
authors.lastname: Pereira
authors.affiliation: Departamento de Ciências Médicas, Faculdade de Medicina, University Nove de Julho, São Paulo, SP, Brazil.
authors.forename: Jean Gonçalves de
authors.initials: JG
authors.lastname: Oliveira
authors.affiliation: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Dionei Freitas de
authors.initials: DF
authors.lastname: Morais
authors.affiliation: Departamento de Psiquiatria e Psicologia Médica, Faculdade de Medicina de São José do Rio Preto, São Paulo, SP, Brazil.
authors.forename: Gerardo Maria de
authors.initials: GM
authors.lastname: Araújo Filho
authors.affiliation: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
authors.forename: Lúcia Helena Neves
authors.initials: LH
authors.lastname: Marques
mesh_terms: D000328:Adult; D004833:Epilepsy, Temporal Lobe / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020019:Neurocysticercosis / Q000150:complications* / Q000601:surgery; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult