title: Kaposi sarcoma secondary to endogenous adrenocorticotropic hormone-dependent Cushing syndrome.
abstract: Kaposi sarcoma (KS) is an angioproliferative tumour that develops as a result of an infection by human herpesvirus 8, which is considered a necessary cause but not sufficient. Other factors - genetic, immunological and environmental - might play a role in the development of the disease. We report a case of KS secondary to endogenous Cushing syndrome (ECS) due to a pituitary adenoma, an association that has been reported only once. We also conducted a search through the Medline and PubMed databases for cases involving KS and ECS, finding only three additional cases that shared common clinical and prognostic features with ours. ECS might favour the development of KS due to immunosuppression. Dermatologists and other clinicians should be aware of this association, as it might be an underdiagnosed condition. It also has an important impact on the management of KS, and based on this review it relies on a good prognosis when ECS is well controlled.
authors.affiliation: Department of Dermatology, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Mayor-Ibarguren
authors.affiliation: Department of Endocrinology, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: M C
authors.initials: MC
authors.lastname: Roldán-Puchalt
authors.affiliation: Department of Internal Medicine, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Sancho-Bueso
authors.affiliation: Department of Neurosurgery, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Pérez-López
authors.affiliation: Department of Radiology, Hospital Ruber Internacional, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Álvarez-Linera
authors.affiliation: Department of Radiology, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Frutos
authors.affiliation: Department of Endocrinology, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Álvarez-Escolá
authors.affiliation: Department of Pathology, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Regojo-Zapata
authors.affiliation: Department of Pathology, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: M J
authors.initials: MJ
authors.lastname: Beato-Merino
authors.affiliation: Department of Dermatology, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Herranz-Pinto
authors.affiliation: Department of Endocrinology, La Paz Hospital, Paseo de la Castellana 261, Madrid, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Lecumberri