title: [Establishment of a comprehensive database for laryngeal cancer related genes and the miRNAs].
abstract: OBJECTIVE
  By collecting and analyzing the laryngeal cancer related genes and the miRNAs, to build a comprehensive laryngeal cancer-related gene database, which differs from the current biological information database with complex and clumsy structure and focuses on the theme of gene and miRNA, and it could make the research and teaching more convenient and efficient.
  
  
  METHODS
  Based on the B/S architecture, using Apache as a Web server, MySQL as coding language of database design and PHP as coding language of web design, a comprehensive database for laryngeal cancer-related genes was established, providing with the gene tables, protein tables, miRNA tables and clinical information tables of the patients with laryngeal cancer.
  
  
  RESULTS
  The established database containsed 207 laryngeal cancer related genes, 243 proteins, 26 miRNAs, and their particular information such as mutations, methylations, diversified expressions, and the empirical references of laryngeal cancer relevant molecules. The database could be accessed and operated via the Internet, by which browsing and retrieval of the information were performed. The database were maintained and updated regularly.
  
  
  CONCLUSIONS
  The database for laryngeal cancer related genes is resource-integrated and user-friendly, providing a genetic information query tool for the study of laryngeal cancer.
authors.affiliation: Department of Medical Informatics, West China School of Medicine, SiChuan University, Chengdu 610041, China.
authors.forename: Mengjiao
authors.initials: M
authors.lastname: Li
authors.forename: Qimin
authors.initials: Q
authors.lastname: E
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu 610041, China; Email: dljl8@163.com.
authors.forename: Jialin
authors.initials: J
authors.lastname: Liu
authors.forename: Tingting
authors.initials: T
authors.lastname: Huang
authors.forename: Chuanyu
authors.initials: C
authors.lastname: Liang
mesh_terms: D030541:Databases, Genetic; D052138:Genes, Neoplasm; D006801:Humans; D020407:Internet; D007822:Laryngeal Neoplasms / Q000235:genetics*; D035683:MicroRNAs / Q000235:genetics*
chemical_list: D035683:MicroRNAs