title: Initial experience with imaging of the lower extremity arteries in an open 1.0 Tesla MRI system using the triggered angiography non-contrast-enhanced sequence (TRANCE) compared to digital subtraction angiography (DSA).
abstract: OBJECTIVE
  The aim of this study was to evaluate the feasibility and validity of arterial lower limb imaging with triggered angiography non-contrast enhanced (TRANCE) in an open MRI at 1.0 Tesla (T) compared to digital subtraction angiography (DSA).
  
  
  METHODS
  ECG-gated, non-contrast-enhanced magnetic resonance angiography (MRA) was performed in a 1.0-T high-field open magnetic resonance imaging (MRI) system which generates a vertical magnetic field. Three acquisition levels were defined (abdominal and pelvic level, arterial segments above the knee and segments below the knee) and a total of 1782 vessel diameter measurements were taken on a total of 11 patients with suspected peripheral arterial occlusive disease (PAOD) (8 men, 3 women; average age 66 years). In each patient, 162 vessel segments (81 each with TRANCE and DSA) were defined and measured. Pearson correlation coefficients were calculated.
  
  
  RESULTS
  At the abdominal/pelvic level, all mean values measured with DSA exceeded the mean values obtained with TRANCE. Above the knee, mean vessel diameters were measured smaller in DSA in six, equal in three, and larger in two vessel segments. Below the knee, all measured averages, except for the tibiofibular tract (TFT) measurements, were larger in TRANCE. In total, two small (≤0.3), two moderate (>0.3), 11 good (>0.5), 10 high (>0.7) and 13 very high (>0.8) correlations were obtained.
  
  
  CONCLUSIONS
  Non-contrast-enhanced imaging of the lower limb arteries using a TRANCE-sequence in a 1.0 T open MRI system is feasible with the protocol presented; however, TRANCE tends to underestimate larger vessels and overestimate smaller vessels compared to DSA.
authors.forename: Britta
authors.initials: B
authors.lastname: Suttmeyer
authors.forename: Ulf
authors.initials: U
authors.lastname: Teichgräber
authors.forename: Hendrik
authors.initials: H
authors.lastname: Rathke
authors.forename: Liane
authors.initials: L
authors.lastname: Albrecht
authors.forename: Felix
authors.initials: F
authors.lastname: Güttler
authors.forename: Bernhard
authors.initials: B
authors.lastname: Schnackenburg
authors.forename: Bernd
authors.initials: B
authors.lastname: Hamm
authors.forename: Maximilian
authors.initials: M
authors.lastname: de Bucourt
mesh_terms: D015901:Angiography, Digital Subtraction / Q000379:methods*; D003287:Contrast Media; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058729:Peripheral Arterial Disease / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media