title: Coronary Artery Involvement of Williams Syndrome in Infants and Surgical Revascularization Strategy.
abstract: Williams syndrome (WS) is a genetic disorder due to deficiency of elastin gene expression. It is characterized by typical somatic abnormalities and a wide range of cardiovascular malformations. Coronary artery involvement is a frequent finding of the syndrome, particularly in those patients with severe supravalvular aortic stenosis. We present the case of an 11-month-old infant affected by WS who developed severe coronary artery disease 2 months after the surgical repair of supravalvular aortic stenosis. The clinical picture and successful surgical revascularization strategy is also described.
authors.affiliation: Cardiac Surgery Unit, "Papa Giovanni XXIII" Hospital, Bergamo, Italy. Electronic address: dfederici@hpg23.it.
authors.forename: Duccio
authors.initials: D
authors.lastname: Federici
authors.affiliation: Cardiovascular Department, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Arianna
authors.initials: A
authors.lastname: Ranghetti
authors.affiliation: Cardiac Surgery Unit, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Merlo
authors.affiliation: Cardiac Surgery Unit, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Amedeo
authors.initials: A
authors.lastname: Terzi
authors.affiliation: Cardiac Surgery Unit, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Giovanni Battista
authors.initials: GB
authors.lastname: Di Dedda
authors.affiliation: Cardiovascular Department, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Simona
authors.initials: S
authors.lastname: Marcora
authors.affiliation: Cardiovascular Department, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Marrone
authors.affiliation: Cardiovascular Department, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Ciuffreda
authors.affiliation: Cardiac Surgery Unit, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Seddio
authors.affiliation: Cardiac Surgery Unit, "Papa Giovanni XXIII" Hospital, Bergamo, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Galletti
mesh_terms: D001026:Coronary Artery Bypass / Q000379:methods*; D023921:Coronary Stenosis / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D003331:Coronary Vessels / Q000601:surgery*; D004452:Echocardiography; D004562:Electrocardiography; D006801:Humans; D007223:Infant; D008297:Male; D014057:Tomography, X-Ray Computed; D018980:Williams Syndrome / Q000150:complications* / Q000601:surgery