title: Regioselective Rhodium-Catalyzed Addition of 1,3-Dicarbonyl Compounds to Terminal Alkynes.
abstract: A new method for the rhodium-catalyzed regioselective C-C bond formation using terminal alkynes and 1,3-dicarbonyl compounds to achieve valuable branched α-allylated 1,3-dicarbonyl products is reported. With a Rh(I)/DPEphos/p-CF3-benzoic acid as the catalyst system, the desired products can be obtained in good to excellent yields and with perfect regioselectivity. A broad range of functional groups were tolerated, and first experimental insights of a plausible reaction mechanism were obtained.
authors.affiliation: Institut für Organische Chemie, Albert-Ludwigs-Universität Freiburg , Albertstr. 21, 79104 Freiburg im Breisgau, Germany.
authors.forename: Thorsten M
authors.initials: TM
authors.lastname: Beck
authors.affiliation: Institut für Organische Chemie, Albert-Ludwigs-Universität Freiburg , Albertstr. 21, 79104 Freiburg im Breisgau, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Breit