title: Vitamin C as Cancer Destroyer, Investigating Sulfhydration, and the Variability in CFTR Interactome.
abstract: Each month, Chemistry & Biology Select highlights a selection of research reports from the recent literature. These highlights are a snapshot of interesting research done across the field of chemical biology. Our December 2015 selection includes an insight into how vitamin C destroys cancer cells, a new method that makes possible the investigatation of sulfhydration, and the mapping of the CFTR interactome and how it depends on the environmental conditions and differs between wild-type and disease-causing mutant.
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000235:genetics*; D005260:Female; D006801:Humans; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics*; D018631:ras Proteins / Q000235:genetics*
chemical_list: D011518:Proto-Oncogene Proteins; D048493:Proto-Oncogene Proteins B-raf; D018631:ras Proteins; D001205:Ascorbic Acid