title: [Predictive value of qualitative assessment of general movements for adverse outcomes at 24 months of age in infants with asphyxia].
abstract: OBJECTIVE
  To investigate the predictive value of the qualitative assessment of general movements (GMs) for adverse outcomes at 24 months of age in full-term infants with asphyxia.
  
  
  METHODS
  A total of 114 full-term asphyxiated infants, who were admitted to the neonatal intensive care unit between 2009 and 2012 and took part in follow-ups after discharge were included in the study. All of them received the qualitative assessment of GMs within 3 months after birth. The development quotient was determined with the Bayley Scales of Infant Development at 24 months of age.
  
  
  RESULTS
  The results of the qualitative assessment of GMs within 3 months after birth showed that among 114 infants, 20 (17.5%) had poor repertoire movements and 7 (6.1%) had cramped-synchronized movements during the writhing movements period; 8 infants (7.0%) had the absence of fidgety movements during the fidgety movements period. The results of development quotient at 24 months of age showed that 7 infants (6.1%) had adverse developmental outcomes: 6 cases of cerebral palsy and mental retardation and 1 case of mental retardation. There was a poor consistency between poor repertoire movements during the writhing movements period and the developmental outcomes at 24 months of age (Kappa=-0.019; P>0.05). There was a high consistency between cramped-synchronized movements during the writhing movements period and the developmental outcomes at 24 months of age (Kappa=0.848; P<0.05), and the results of predictive values of cramped-synchronized movements were shown as follows: predictive validity 98.2%, sensitivity 85.7%, specificity 99.1%, positive predictive value 85.7%, and negative predictive value 99.1%. There was a high consistency between the absence of fidgety movements during the fidgety movements period and the developmental outcomes at 24 months of age (Kappa=0.786; P<0.05), and its predictive values were expressed as follows: predictive validity 97.4%, sensitivity 85.7%, specificity 98.1%, positive predictive value 75.0%, and negative predictive value 99.1%.
  
  
  CONCLUSIONS
  Cramped-synchronized movements and absence of fidgety movements can predict adverse developmental outcomes at 24 months of age in full-term infants with asphyxia.
authors.affiliation: Department of Pediatrics, Third Affiliated Hospital of Anhui Medical University, Hefei 230000, China. wenxiaohong2007@163.com.
authors.forename: Nan
authors.initials: N
authors.lastname: Chen
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Wen
authors.forename: Jin-Hua
authors.initials: JH
authors.lastname: Huang
authors.forename: Shui-Yun
authors.initials: SY
authors.lastname: Wang
authors.forename: Yue-E
authors.initials: YE
authors.lastname: Zhu
mesh_terms: D001238:Asphyxia Neonatorum / Q000503:physiopathology*; D002657:Child Development; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009068:Movement; D011237:Predictive Value of Tests; D036301:Qualitative Research