title: Regulating the Conformation of Methylazacalix[6]pyridine by Oligonucleotide BCL-2 2345 and Its Recognition of Hydroxymethylpiperazinofullerene.
abstract: Calixaromatics have attracted much attention on molecular recognition owing to their flexible conformations, cavity structures, versatile recognition properties, and functions. However, conformational control of calixaromatics is still a challenging topic in the field of calixaromatics. Therefore, we explore the possibility to control the chirality of achiral calixaromatics, methylazacalix[6]pyridine (abbreviated as MACP6), by templating of DNA. We have found that MACP6 with opposite chirality can be achieved by controlling the secondary structure of bcl-2 2345 DNA. Furthermore, MACP6 with different chirality has been used to recognize fullerene derivatives in aqueous solution. Our results have provided a possible approach to construct chiral calixaromatics.
authors.affiliation: Graduate University of the Chinese Academy of Sciences , Beijing 100049, People's Republic of China.
authors.forename: Ai-Jiao
authors.initials: AJ
authors.lastname: Guan
authors.forename: En-Xuan
authors.initials: EX
authors.lastname: Zhang
authors.forename: Jun-Feng
authors.initials: JF
authors.lastname: Xiang
authors.forename: Qian-Fan
authors.initials: QF
authors.lastname: Yang
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.affiliation: Graduate University of the Chinese Academy of Sciences , Beijing 100049, People's Republic of China.
authors.forename: Hong-Xia
authors.initials: HX
authors.lastname: Sun
authors.forename: De-Xian
authors.initials: DX
authors.lastname: Wang
authors.forename: Qi-Yu
authors.initials: QY
authors.lastname: Zheng
authors.forename: Guang-Zhi
authors.initials: GZ
authors.lastname: Xu
authors.forename: Ya-Lin
authors.initials: YL
authors.lastname: Tang
keywords: G-quadruplex; calixaromatics; chirality; conformational regulation