title: Binding Hydrated Anions with Hydrophobic Pockets.
abstract: Using a combination of isothermal titration calorimetry and quantum and molecular dynamics calculations, we demonstrate that relatively soft anions have an affinity for hydrophobic concavity. The results are consistent with the anions remaining partially hydrated upon binding, and suggest a novel strategy for anion recognition.
authors.affiliation: Department of Chemistry, Tulane University , New Orleans, Louisiana 70118, United States.
authors.forename: Punidha
authors.initials: P
authors.lastname: Sokkalingam
authors.affiliation: Department of Chemistry, University of New Orleans , New Orleans, Louisiana 70148, United States.
authors.forename: Joshua
authors.initials: J
authors.lastname: Shraberg
authors.affiliation: Department of Chemistry, University of New Orleans , New Orleans, Louisiana 70148, United States.
authors.forename: Steven W
authors.initials: SW
authors.lastname: Rick
authors.affiliation: Department of Chemistry, Tulane University , New Orleans, Louisiana 70118, United States.
authors.forename: Bruce C
authors.initials: BC
authors.lastname: Gibb
mesh_terms: D000838:Anions / Q000737:chemistry*; D002151:Calorimetry / Q000379:methods*; D057927:Hydrophobic and Hydrophilic Interactions; D015394:Molecular Structure
chemical_list: D000838:Anions