title: Sociodemographic impact on survival in unresectable hepatocellular carcinoma: a survival epidemiology and end results study.
abstract: To investigate outcomes in unresectable hepatocellular carcinoma (HCC) patients stratified by sociodemographic and clinical factors in a population study.
  
  
  
  Surveillance, Epidemiology and End Results (SEER) database was used to identify patients diagnosed in 2000-2011. Overall survival (OS) was stratified using patient sociodemographic characteristics and American Joint Commission on Cancer (AJCC) staging. Log-rank test and Cox proportional hazard models were used to identify prognostic factors of OS.
  
  
  
  In patients with AJCC stage I and II unresectable HCC, prolonged OS was correlated with being married, younger age, ethnicity, geographic location, living in large urban areas, being insured and higher income and education levels.
  
  
  
  In AJCC stage I and II unresectable HCC patients with favorable sociodemographic factors, prolonged OS maybe in part related to better access to cancer-directed therapy.
authors.affiliation: Department of Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: Nima
authors.initials: N
authors.lastname: Kokabi
authors.affiliation: Department of Diagnostic Radiology, Division of Interventional Radiology, Yale University School of Medicine, New Haven, CT 06519, USA.
authors.forename: Minzhi
authors.initials: M
authors.lastname: Xing
authors.forename: Richard
authors.initials: R
authors.lastname: Duszak
authors.affiliation: Department of Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Duszak
authors.affiliation: Department of Health Policy & Management, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
authors.forename: David H
authors.initials: DH
authors.lastname: Howard
authors.affiliation: Department of Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: Kimberly E
authors.initials: KE
authors.lastname: Applegate
authors.affiliation: Department of Radiology & Imaging Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Camacho
authors.affiliation: Department of Diagnostic Radiology, Division of Interventional Radiology, Yale University School of Medicine, New Haven, CT 06519, USA.|Yale Cancer Center, Yale University, New Haven, CT 06520-8028, USA.
authors.forename: Hyun S
authors.initials: HS
authors.lastname: Kim
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000453:epidemiology / Q000401:mortality* / Q000473:pathology*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008113:Liver Neoplasms / Q000453:epidemiology / Q000401:mortality* / Q000473:pathology*; D008297:Male; D009367:Neoplasm Staging; D063868:Patient Outcome Assessment; D011159:Population Surveillance; D012307:Risk Factors; D018426:SEER Program; D014481:United States / Q000453:epidemiology
keywords: HCC; SEER; access to care; cancer-directed therapy; demographic; disparity; socioeconomic; survival; unresectable