title: Presynaptic Inhibition in the Striatum of the Basal Ganglia Improves Pattern Classification and Thus Promotes Superior Goal Selection.
abstract: This review article takes a multidisciplinary approach to understand how presynaptic inhibition in the striatum of the basal ganglia (BG) contributes to pattern classification and the selection of goals that control behavior. It is a difficult problem both because it is multidimensional and because it is has complex system dynamics. We focus on the striatum because, as the main site for input to the BG, it gets to decide what goals are important to consider.
authors.affiliation: Department of Physics and Astronomy, Northwestern University Evanston, IL, USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Schwab
authors.affiliation: Department of Physiology, Northwestern University Chicago, IL, USA.
authors.forename: James C
authors.initials: JC
authors.lastname: Houk
keywords: basal ganglia; pattern classification; presynaptic inhibition; schizophrenia; striatum