title: Incidence and Predictors of In-stent Re-Stenosis in the Superficial Femoral Artery: Evaluation of Long-Term Outcomes by Color Duplex Ultrasound.
abstract: This study aimed to investigate the incidence and predictors of in-stent re-stenosis (ISR) for nitinol stents in the superficial femoral artery (SFA) by color duplex ultrasound (CDU). In total, 235 patients undergoing SFA stenting were included in the present study. The cumulative ISR rates at 3, 6, 12, 24 and 36 mo post-procedure were 5.4%, 24.0%, 49.0%, 61.5% and 71.5%, respectively. The markedly low peak systolic velocity of the popliteal artery (PSV2) post-operation was inversely correlated with the ISR. The threshold for ≥50% re-stenosis was PSV2 ≤ 63 cm/s with 86.6% sensitivity and 90.5% specificity. With regard to re-occlusion, the PSV2 was ≤40 cm/s with 98.1% sensitivity and 93.4% specificity. Cox regression analysis indicated that the cumulative stent length, diabetes, and pre-stent stenosis level were independent risk factors of ISR. In conclusion, the ISR incidence after SFA stenting is relatively high and CDU follow-up is a feasible method for evaluating ISR.
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Mingjie
authors.initials: M
authors.lastname: Gao
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Yunlu
authors.initials: Y
authors.lastname: Tao
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Mingyu
authors.initials: M
authors.lastname: Xia
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Zhu
authors.initials: Z
authors.lastname: Tong
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China.
authors.forename: Chengbei
authors.initials: C
authors.lastname: Hou
authors.affiliation: Department of Vascular Ultrasonography, Xuanwu Hospital, Capital Medical University, Beijing, China. Electronic address: dryanghua99@163.com.
authors.forename: Yang
authors.initials: Y
authors.lastname: Hua
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D015897:Comorbidity; D048909:Diabetes Complications / Q000453:epidemiology*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000601:surgery*; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color / Q000379:methods / Q000706:statistics & numerical data*
keywords: Color duplex ultrasound; Popliteal artery; Re-stenosis; Stent; Superficial femoral artery