title: l-myc Polymorphism in Gastric Cancer, Lung Cancer, and Hepatocellular Carcinoma.
abstract: OBJECTIVE
  This study was performed to see if a particular polymorphism in the l-myc, a nuclear oncogene at the 1p32 locus, might be associated with greater risk of gastric cancer, lung cancer and hepatocellular carcinomas (HCC) in Korean patients.
  
  
  METHODS
  Genomic DNA, derived from patients diagnosed with gastric cancer (n=57), lung cancer (n=39), HCC (n=35) and healthy individuals (n= 176), was examined. The l-myc polymorphism under study was visualized by PCR followed by EcoRI digestion.
  
  
  RESULTS
  There was no significant difference in the distribution of the l-myc polymorphism genotypes and allele frequencies between the cancer patients and the controls.
  
  
  CONCLUSIONS
  The l-myc polymorphism does not appear to be indicative of elevated risk of cancers of the stomach, lung and HCC.
authors.forename: Min Su
authors.initials: MS
authors.lastname: Park
authors.forename: Sae Bin
authors.initials: SB
authors.lastname: Jung
authors.forename: Yeon Hee
authors.initials: YH
authors.lastname: Park
authors.forename: Bong Seog
authors.initials: BS
authors.lastname: Kim
authors.forename: Hyun Ju
authors.initials: HJ
authors.lastname: Park
authors.forename: Hee Jae
authors.initials: HJ
authors.lastname: Lee
authors.forename: Soon Ae
authors.initials: SA
authors.lastname: Kim
authors.forename: Bong Keun
authors.initials: BK
authors.lastname: Choe
authors.forename: Joo Ho
authors.initials: JH
authors.lastname: Chung
keywords: Gastric neoplasm; Hepatocellular carcinoma; Lung neoplasm; l-myc polymorphism