title: Assessing Medication Adherence as a Standard of Care in Pediatric Oncology.
abstract: Poor adherence to pediatric cancer treatment protocols may prevent children and adolescents from realizing the potential benefits of therapy. This paper presents the evidence for a standard of care for supporting medication adherence. Databases were reviewed for articles examining adherence and including children and/or adolescents with cancer. Fourteen articles (i.e., qualitative, quantitative, review, and randomized clinical trials) were evaluated for rigor. There is moderate-quality evidence to support a strong recommendation for adherence to be assessed routinely and monitored throughout the treatment. Integrating the proposed clinical procedures into standard clinical care may improve outcomes for children and adolescents with cancer.
authors.affiliation: Patient and Family Wellness Center, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.|Division of Behavioral Medicine and Clinical Psychology, Center for Adherence and Self-Management, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Ahna L H
authors.initials: AL
authors.lastname: Pai
authors.affiliation: Patient and Family Wellness Center, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.|Division of Behavioral Medicine and Clinical Psychology, Center for Adherence and Self-Management, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Meghan E
authors.initials: ME
authors.lastname: McGrady
mesh_terms: D000293:Adolescent; D002648:Child; D006801:Humans; D008495:Medical Oncology / Q000592:standards*; D055118:Medication Adherence; D009369:Neoplasms / Q000188:drug therapy*; D010372:Pediatrics / Q000592:standards*; D059039:Standard of Care
keywords: adherence; adolescent; cancer; child; oncology; self-management