title: Revision stapes surgery for lysis of the long process of the incus: comparing hydroxyapatite bone cement versus malleovestibulopexy and total ossicular replacement prosthesis.
abstract: The objective of the study was to report audiological results in revision stapes surgery, comparing hydroxyapatite (HAP) bone cement, malleovestibular (MV) prosthesis, and total ossicular replacement prosthesis (TORP). The study is a retrospective case review conducted in a tertiary referral center. Patients treated for revision stapes surgery from 2010 to 2014, where a lysis of the long process of the incus (LPI) was observed with the use of HAP bone cement, MV prosthesis, or a TORP were included in the study. The main outcomes measured were pre- and postoperative bone conduction (BC) and air conduction (AC) pure-tone averages (PTA) (0.5, 1, 2, 3 kHz), including high frequencies BC (HFBC) (1, 2, 3, 4 kHz) and air-bone gap (ABG). 107 revision stapes surgery were performed in 96 ears. Main cause of failure was LPI lysis in 38 cases (39.6 %). 31 patients were analyzed: HAP bone cement was used in 11 patients (Group I), MV prosthesis in ten patients (Group II), and TORP in ten patients (Group III). The mean post-operative ABG was 10.7 dB (±7.4) (p = 0.003), 10.7 dB (±8.8) (p = 0.001), and 16.9 dB (±9.8) (p = 0.001), respectively. There were no significant differences between groups. In Group I, the mean change in HFBC revealed an improvement of 5.6 dB (±7.9) (p = 0.03), while in Group III there was a significant deterioration of the thresholds of 5.8 dB (±7.6) (p = 0.04). There were no cases of post-operative anacusis. In revision stapes surgery when LPI is eroded, we recommend to perform a cement ossiculoplasty for stabilizing a standard Teflon piston when LPI is still usable, the LPI lengthening with cement being not recommended. When LPI is too eroded, we prefer performing a malleovestibulopexy, and reserve TORP for cases with a bad anatomical presentation.
authors.affiliation: Département d'ORL et de Chirurgie Cervico-Maxillo-Faciale et d'Audiophonologie, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France. vincent.pitiot01@chu-lyon.fr.
authors.forename: Vincent
authors.initials: V
authors.lastname: Pitiot
authors.affiliation: Département d'ORL et de Chirurgie Cervico-Maxillo-Faciale et d'Audiophonologie, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France.
authors.forename: Ruben
authors.initials: R
authors.lastname: Hermann
authors.affiliation: Université Lyon 1, 69000, Lyon, France.|Département d'Oto-neurochirurgie, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.|Lyon Neuroscience Research Center, Brain Dynamics and Cognition Team, CRNL, INSERM U1028, CNRS UMR5292, 69000, Lyon, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Tringali
authors.affiliation: Université Lyon 1, 69000, Lyon, France.|Département d'Oto-neurochirurgie, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.|Lyon Neuroscience Research Center, Brain Dynamics and Cognition Team, CRNL, INSERM U1028, CNRS UMR5292, 69000, Lyon, France.
authors.forename: Christian
authors.initials: C
authors.lastname: Dubreuil
authors.affiliation: Département d'ORL et de Chirurgie Cervico-Maxillo-Faciale et d'Audiophonologie, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France.|Université Lyon 1, 69000, Lyon, France.|Lyon Neuroscience Research Center, Brain Dynamics and Cognition Team, CRNL, INSERM U1028, CNRS UMR5292, 69000, Lyon, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Truy
mesh_terms: D000328:Adult; D001299:Audiometry / Q000379:methods; D001843:Bone Cements / Q000009:adverse effects / Q000627:therapeutic use; D057186:Comparative Effectiveness Research; D005260:Female; D005602:France; D006314:Hearing Loss, Conductive / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D006882:Hydroxyapatites / Q000009:adverse effects / Q000627:therapeutic use; D007188:Incus / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019933:Ossicular Replacement / Q000009:adverse effects / Q000379:methods; D011183:Postoperative Complications / Q000175:diagnosis / Q000601:surgery; D012086:Reoperation / Q000379:methods / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013201:Stapes Surgery / Q000009:adverse effects / Q000379:methods; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D006882:Hydroxyapatites; C475044:hydroxyapatite cement
keywords: Hearing results; Hydroxyapatite bone cement; Long process of the incus; Ossiculoplasty; Otosclerosis