title: [Cellular Mechanisms of Morphological and Functional Changes of the Arterial Wall With Age and the Role of Statin Therapy in the Prevention].
abstract: We discuss the cellular and molecular mechanisms of morphological and functional changes of the arterial wall in the aging process and the possibility of using statin therapy for the prevention of early vascular aging.
authors.forename: I D
authors.initials: ID
authors.lastname: Strazhesko
authors.forename: O N
authors.initials: ON
authors.lastname: Tkacheva
mesh_terms: D000375:Aging; D001158:Arteries / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000473:pathology / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D059289:Vascular Stiffness / Q000187:drug effects*
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors