title: Regulatory Solutions to the Problem of High Generic Drug Costs.
abstract: Recent reports have highlighted dramatic price increases for several older generic drugs, including a number of essential products used to treat deadly infectious diseases. Although most of these medicines have been widely available at reasonable prices for decades, some manufacturers have seized on unique features of the pharmaceutical marketplace to seek substantial profits. In this Perspective, we examine limitations in current price regulation among public and private payors and consider several reforms that could address the problem of expensive generic drugs through improved competition.
authors.affiliation: Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine , Brigham and Women's Hospital and Harvard Medical School , Boston, Massachusetts.
authors.forename: Jing
authors.initials: J
authors.lastname: Luo
authors.affiliation: Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine , Brigham and Women's Hospital and Harvard Medical School , Boston, Massachusetts.
authors.forename: Ameet
authors.initials: A
authors.lastname: Sarpatwari
authors.affiliation: Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine , Brigham and Women's Hospital and Harvard Medical School , Boston, Massachusetts.
authors.forename: Aaron S
authors.initials: AS
authors.lastname: Kesselheim
keywords: FDA; drug costs; drug prices; generic drugs