title: The Brain Symptom and Impact Questionnaire in brain metastases patients: a prospective long-term follow-up study.
abstract: OBJECTIVE
  To assess the ability of the Brain Metastases Symptom and Impact Questionnaire (BASIQ) in evaluating symptoms and impact on daily life.
  
  
  METHODS
  Patients with brain metastases completed BASIQ, Functional Assessment of Cancer Therapy-General, FACT-Brain at baseline and at 1, 2 and 3 months follow-ups.
  
  
  RESULTS
  Thirty-six patients completed all follow-ups. BASIQ correlated well (r ≥ 0.40) with FACT subscales, except for social/family and emotional wellbeing. Linear regression analysis found no significant changes in quality of life (QOL) over time in both the BASIQ and FACT scales. Therefore, the two questionnaires coincide as both detected nonchanges.
  
  
  CONCLUSIONS
  The ability of the BASIQ in evaluating symptoms and impact on over longer assessment periods was supported by the FACT questionnaires.
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Natalie
authors.initials: N
authors.lastname: Pulenzas
authors.affiliation: Oncology AbbVie, Abbott Park, IL, USA.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Ray
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Liying
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Rachel
authors.initials: R
authors.lastname: McDonald
authors.affiliation: Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
authors.forename: David
authors.initials: D
authors.lastname: Cella
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Leigha
authors.initials: L
authors.lastname: Rowbottom
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Arjun
authors.initials: A
authors.lastname: Sahgal
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Hany
authors.initials: H
authors.lastname: Soliman
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: May
authors.initials: M
authors.lastname: Tsao
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Cyril
authors.initials: C
authors.lastname: Danjoux
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Breanne
authors.initials: B
authors.lastname: Lechner
authors.affiliation: Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Edward
authors.initials: E
authors.lastname: Chow
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000503:physiopathology*; D001932:Brain Neoplasms / Q000401:mortality / Q000523:psychology* / Q000628:therapy; D005260:Female; D018303:Ganglioglioma / Q000401:mortality / Q000523:psychology* / Q000628:therapy; D006801:Humans; D017567:Karnofsky Performance Status; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000503:physiopathology*; D011446:Prospective Studies; D011788:Quality of Life; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013997:Time Factors; D055815:Young Adult
keywords: BASIQ; brain metastases; quality of life