title: Impact of Pregnancy on Weight Loss and Quality of Life Following Gastric Banding.
abstract: Despite pregnancy being a common event following laparoscopic adjustable gastric banding (LAGB), there is little comprehensive data regarding its effect on postoperative outcome. The aim of this study was to assess the impact of pregnancy on the postoperative changes in quality of life (QOL) and total weight loss 3 years after LAGB.
  
  
  
  Multi-institutional, France.
  
  
  
  This is a study of the subgroup of 561 women of childbearing age included in a 3-year prospective multicenter trial assessing the results of patients undergoing LAGB surgery. Data from the 61 women who got pregnant and delivered during the follow-up period were compared with the 270 who did not.
  
  
  
  Pregnant women achieved lower final weight loss compared to the non-pregnant group [final body mass index (BMI) 35.4 vs. 31.1 kg/m(2), p < 0.0001; excess weight loss (%EBL) 43.6 vs. 64.7 %, p < 0.0001]. Longitudinal assessment demonstrated pregnancy as a significant and independent factor of poor weight loss (p < 0.0001). The timing of conception after LAGB (between the first 18 months or after) had no significant impact on weight loss changes. There was no significant difference in short form-36 health survey (SF-36) QOL scores between both groups.
  
  
  
  Pregnancy following gastric banding affects negatively postoperative final weight loss, even if occurring 18 months postoperatively, but has no effect on QOL improvement.
authors.affiliation: Department of Endocrinology, Diabetology and Nutrition, University Hospital Lyon Sud, Lyon, France. cpapastathi@yahoo.gr.|University Claude Bernard Lyon 1, Lyon, France. cpapastathi@yahoo.gr.
authors.forename: Chrysoula
authors.identifier: 0000-0001-8202-7933
authors.initials: C
authors.lastname: Papastathi
authors.affiliation: Department of Endocrinology, Diabetology and Nutrition, University Hospital Lyon Sud, Lyon, France.|University Claude Bernard Lyon 1, Lyon, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Disse
authors.affiliation: University Claude Bernard Lyon 1, Lyon, France.|Hospices Civils de Lyon, Pôle Information Médicale Evaluation Recherche, Unité d'Epidémiologie Clinique Lyon, Lyon, France.
authors.forename: Julien
authors.initials: J
authors.lastname: Berthiller
authors.affiliation: Department of Endocrinology, Diabetology and Nutrition, University Hospital Lyon Sud, Lyon, France.|University Claude Bernard Lyon 1, Lyon, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Laville
authors.affiliation: University Claude Bernard Lyon 1, Lyon, France.|Department of Digestive Surgery, University Hospital Edouard Herriot, Lyon, France.
authors.forename: Christian
authors.initials: C
authors.lastname: Gouillat
authors.affiliation: University Claude Bernard Lyon 1, Lyon, France.|Department of Digestive Surgery, University Hospital Edouard Herriot, Lyon, France.
authors.forename: Maud
authors.initials: M
authors.lastname: Robert
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005602:France / Q000453:epidemiology; D015391:Gastroplasty / Q000379:methods; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D008137:Longitudinal Studies; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery*; D011184:Postoperative Period; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000523:psychology; D011446:Prospective Studies; D011788:Quality of Life; D016896:Treatment Outcome; D015431:Weight Loss; D055815:Young Adult
keywords: Bariatric surgery; Gastric band; Obesity; Pregnancy; Quality of life; Weight loss