title: Acute leg pain with suspected beginning leg compartment syndrome and deep vein thrombosis as differential diagnoses in an unusual presentation of Brodie's abscess: a case report.
abstract: BACKGROUND
  Brodie's abscess is an uncommon form of subacute osteomyelitis where the main presenting symptom is mild to moderate pain of insidious onset for several months' duration. We report a case of a patient presenting with acute leg pain resembling that of a deep vein thrombosis, and a beginning leg compartment syndrome following a suspected ruptured Baker's cyst. Our case is unusual because of the acute presentation of the Brodie's abscess with acute leg pain and acute swelling without any preceding trauma; to the best of our knowledge, this presentation has not been reported before.
  
  
  METHODS
  A 17-year-old white boy presented to our out-patient clinic with a 6-month history of pain in his left knee joint of insidious onset. There was no history of trauma to the extremity. After performing physical and radiological (X-ray) examinations, we initially diagnosed medial meniscus damage. One week later he presented to our emergency department with acute sudden increase in the pain and swelling of his left knee, and pain and swelling of his left leg, without any trauma. Deep vein thrombosis and beginning leg compartment syndrome from ruptured Baker's cyst were initially diagnosed. Magnetic resonance imaging was performed and Brodie's abscess was the most probable diagnosis. We performed open surgical debridement and curettage with drainage of the abscess and administered postoperative antibiotics. He presented to our out-patient clinic 3 months postoperatively, where he was pain-free with no residual local tenderness.
  
  
  CONCLUSIONS
  In cases of sudden acute increase in joint or extremity pain or swelling that has been insidiously present for months, Brodie's abscess should be considered as one of the differential diagnoses, as it may present acutely in cases with accompanying fasciitis and myositis and be clinically mistaken for deep vein thrombosis or limb compartment. Magnetic resonance imaging remains the gold standard imaging study, and surgical treatment followed by postoperative antibiotics remains the standard treatment.
authors.affiliation: Abteilung für Orthopädie, Universitätsmedizin Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany. ahammad116@gmail.com.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Hammad
authors.affiliation: Abteilung für Orthopädie, Universitätsmedizin Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany. philip.leute@med.uni-goettingen.de.
authors.forename: Philip Johannes Felix
authors.initials: PJ
authors.lastname: Leute
authors.affiliation: Abteilung für Orthopädie, Universitätsmedizin Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany. isabel.hoffmann@med.uni-goettingen.de.
authors.forename: Isabel
authors.initials: I
authors.lastname: Hoffmann
authors.affiliation: Abteilung für Orthopädie, Universitätsmedizin Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany. sebastian.hoppe@med.uni-goetingen.de.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Hoppe
authors.affiliation: Abteilung für Orthopädie, Universitätsmedizin Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany. stefan.lakemeier@med.uni-goettingen.de.
authors.forename: Stefan
authors.initials: S
authors.lastname: Lakemeier
authors.affiliation: Abteilung für Orthopädie, Universitätsmedizin Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany. michael.klinger@med.uni-goettingen.de.
authors.forename: Hans-Michael
authors.initials: HM
authors.lastname: Klinger
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000628:therapy; D059787:Acute Pain / Q000209:etiology / Q000473:pathology*; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003161:Compartment Syndromes / Q000175:diagnosis*; D003475:Curettage / Q000379:methods; D003646:Debridement / Q000379:methods; D003937:Diagnosis, Differential; D004322:Drainage / Q000379:methods; D006801:Humans; D007719:Knee Joint / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000175:diagnosis*
chemical_list: D000900:Anti-Bacterial Agents