title: Evaluation of the BinaxNOW® Streptococcus pneumoniae antigen test on fresh, frozen and concentrated urine samples in elderly patients with and without community-acquired pneumonia.
abstract: We evaluated the BinaxNOW® urine antigen test in elderly. For fresh un-concentrated urine samples, the sensitivity for pneumococcal pneumonia was 63% and specificity 97%. After freezing and concentration, the results comparable to positive control line in intensity at 60 min gave high sensitivity (81%) with no loss in specificity (96%).
authors.affiliation: Department of Health Protection, National Institute for Health and Welfare, Oulu, Finland. Electronic address: annika.saukkoriipi@thl.fi.
authors.forename: Annika
authors.initials: A
authors.lastname: Saukkoriipi
authors.affiliation: GSK Vaccines, Wavre, Belgium.
authors.forename: Thierry
authors.initials: T
authors.lastname: Pascal
authors.affiliation: Department of Health Protection, National Institute for Health and Welfare, Tampere, Finland.
authors.forename: Arto A
authors.initials: AA
authors.lastname: Palmu
mesh_terms: D000368:Aged; D000942:Antigens, Bacterial / Q000652:urine*; D001431:Bacteriological Techniques / Q000295:instrumentation / Q000379:methods*; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000382:microbiology / Q000652:urine*; D003955:Diagnostic Tests, Routine / Q000379:methods; D005615:Freezing; D006801:Humans; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis / Q000382:microbiology / Q000652:urine*; D013296:Streptococcus pneumoniae / Q000276:immunology / Q000302:isolation & purification*; D014556:Urine / Q000737:chemistry / Q000382:microbiology
chemical_list: D000942:Antigens, Bacterial
keywords: Community-acquired pneumonia; Streptococcus pneumoniae; Urine antigen