title: Clinical enigma: A rare case of clear cell odontogenic carcinoma.
abstract: Clear cell odontogenic carcinoma is a rare, aggressive neoplasm of the jaw with only 74 reported cases. It occurs predominantly in the mandibular anterior region during fifth to seventh decades of life. Clinically it manifests as intra-bony swelling with a variable degree of pain. Microscopically, it reveals nests of cells with clear cytoplasm in connective tissue stroma arranged in different patterns. It is often misdiagnosed due to the rarity of lesion and confusing histopathology. Immunohistochemical staining plays an intricate role to uncertain the native of the clear cell to reach a confirmative diagnosis. The article aims to highlight the clinicopathologic features of clear cell odontogenic carcinoma in a middle-aged man with special emphasis on its differential diagnosis.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Buraydah Private Dental College, Buraydah 31717, Saudi Arabia.
authors.forename: Cheshta
authors.initials: C
authors.lastname: Walia
authors.affiliation: Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India.
authors.forename: Rudra Prasad
authors.initials: RP
authors.lastname: Chatterjee
authors.affiliation: Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India.
authors.forename: Sanchita
authors.initials: S
authors.lastname: Kundu
authors.affiliation: Department of Orthodontics, Buraydah Private Dental College, Buraydah 31717, Saudi Arabia.
authors.forename: Sudip
authors.initials: S
authors.lastname: Roy
keywords: Biphasic pattern; clear cell odontogenic carcinoma; clear cells