title: Tissue Tracking Technology for Assessing Cardiac Mechanics: Principles, Normal Values, and Clinical Applications.
abstract: Tissue tracking technologies such as speckle tracking echocardiography and feature tracking cardiac magnetic resonance have enhanced the noninvasive assessment of myocardial deformation in clinical research and clinical practice. The widespread enthusiasm for using tissue tracking techniques in research and clinical practice stems from the ready applicability of these technologies to routine echocardiographic or cardiac magnetic resonance images. The technology is common to both modalities, and derived parameters to describe myocardial mechanics are the similar, albeit with different accuracies. We provide an overview of the normal values and reproducibility of the clinically applicable parameters, together with their clinical validation. The use of these technologies in different clinical scenarios, and the additive value to current imaging diagnostics are discussed.
authors.affiliation: Laboratory for Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
authors.forename: Piet
authors.initials: P
authors.lastname: Claus
authors.affiliation: Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Internal Medicine, Medical Division, National Research Centre, Dokki, Cairo, Egypt.
authors.forename: Alaa Mabrouk Salem
authors.initials: AMS
authors.lastname: Omar
authors.affiliation: Department of Engineering and Architecture, University of Trieste, Trieste, Italy.
authors.forename: Gianni
authors.initials: G
authors.lastname: Pedrizzetti
authors.affiliation: Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
authors.forename: Partho P
authors.initials: PP
authors.lastname: Sengupta
authors.affiliation: Institute of Cardiovascular Imaging, Goethe University Frankfurt and German Centre for Cardiovascular Research ([DZHK], partner site Rhine-Main), Frankfurt, Germany. Electronic address: eike.nagel@cardiac-imaging.org.
authors.forename: Eike
authors.initials: E
authors.lastname: Nagel
mesh_terms: D057791:Cardiac Imaging Techniques / Q000379:methods; D002318:Cardiovascular Diseases / Q000175:diagnosis*; D019560:Echocardiography, Three-Dimensional / Q000379:methods*; D005260:Female; D006334:Heart Function Tests; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D017202:Myocardial Ischemia / Q000175:diagnosis; D012016:Reference Values; D015203:Reproducibility of Results
keywords: cardiac mechanics; feature-tracking cardiac magnetic resonance imaging; myocardial function; speckle tracking echocardiography