title: Real-time PCR for Strongyloides stercoralis-associated meningitis.
abstract: Four immunocompromised patients, immigrants from Ethiopia, presented with diverse clinical manifestations of meningitis associated with Strongyloides stercoralis dissemination as determined by identification of intestinal larvae. The cerebrospinal fluid of 3 patients was tested by a validated (for stool) real-time PCR for S. stercoralis and was found positive, establishing this association.
authors.affiliation: Infectious Diseases Unit, Kaplan Medical Center, Rehovot, Israel, affiliated to the School of Medicine, Hebrew University and Hadassah, Jerusalem, Israel. Electronic address: nadir_e@clalit.org.il.
authors.forename: Eyal
authors.initials: E
authors.lastname: Nadir
authors.affiliation: Central Laboratories, Reference Parasitology Laboratory, Ministry of Health, Jerusalem, Israel.
authors.forename: Tamar
authors.initials: T
authors.lastname: Grossman
authors.affiliation: Infectious Diseases Unit, Kaplan Medical Center, Rehovot, Israel, affiliated to the School of Medicine, Hebrew University and Hadassah, Jerusalem, Israel.
authors.forename: Pnina
authors.initials: P
authors.lastname: Ciobotaro
authors.affiliation: Department of Internal Medicine B, Kaplan Medical Center, Rehovot, Israel.
authors.forename: Malka
authors.initials: M
authors.lastname: Attali
authors.affiliation: Infectious Diseases Unit, Kaplan Medical Center, Rehovot, Israel, affiliated to the School of Medicine, Hebrew University and Hadassah, Jerusalem, Israel.
authors.forename: Daniel
authors.initials: D
authors.lastname: Barkan
authors.affiliation: Microbioly Laboratory, Kaplan Medical Center, Rehovot, Israel.
authors.forename: Rita
authors.initials: R
authors.lastname: Bardenstein
authors.affiliation: Infectious Diseases Unit, Kaplan Medical Center, Rehovot, Israel, affiliated to the School of Medicine, Hebrew University and Hadassah, Jerusalem, Israel. Electronic address: oren_z@clalit.org.il.
authors.forename: Oren
authors.initials: O
authors.lastname: Zimhony
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008581:Meningitis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*; D008875:Middle Aged; D059208:Parasite Load; D060888:Real-Time Polymerase Chain Reaction / Q000379:methods; D012307:Risk Factors; D017171:Strongyloides stercoralis / Q000235:genetics*; D013322:Strongyloidiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics
keywords: Immunocompromised host; Meningitis; PCR; Strongyloides stercoralis