title: Scalable synthesis and post-modification of a mesoporous metal-organic framework called NU-1000.
abstract: The synthesis of NU-1000, a highly robust mesoporous (containing pores >2 nm) metal-organic framework (MOF), can be conducted efficiently on a multigram scale from inexpensive starting materials. Tetrabromopyrene and (4-(ethoxycarbonyl)phenyl)boronic acid can easily be coupled to prepare the requisite organic strut with four metal-binding sites in the form of four carboxylic acids, while zirconyl chloride octahydrate is used as a precursor for the well-defined metal oxide clusters. NU-1000 has been reported as an excellent candidate for the separation of gases, and it is a versatile scaffold for heterogeneous catalysis. In particular, it is ideal for the catalytic deactivation of nerve agents, and it shows great promise as a new generic platform for a wide range of applications. Multiple post-synthetic modification protocols have been developed using NU-1000 as the parent material, making it a potentially useful scaffold for several catalytic applications. The procedure for the preparation of NU-1000 can be scaled up reliably, and it is suitable for the production of 50 g of the tetracarboxylic acid containing organic linker and 200 mg-2.5 g of NU-1000. The entire synthesis is performed without purification by column chromatography and can be completed within 10 d.
authors.affiliation: Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
authors.forename: Timothy C
authors.identifier: http://orcid.org/0000-0002-2736-2488
authors.initials: TC
authors.lastname: Wang
authors.affiliation: Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
authors.forename: Nicolaas A
authors.initials: NA
authors.lastname: Vermeulen
authors.affiliation: Material Science Division, Argonne National Laboratory, Argonne, Illinois, USA.
authors.forename: In Soo
authors.initials: IS
authors.lastname: Kim
authors.affiliation: Material Science Division, Argonne National Laboratory, Argonne, Illinois, USA.
authors.forename: Alex B F
authors.initials: AB
authors.lastname: Martinson
authors.affiliation: Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
authors.forename: J Fraser
authors.initials: JF
authors.lastname: Stoddart
authors.affiliation: Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
authors.forename: Joseph T
authors.initials: JT
authors.lastname: Hupp
authors.affiliation: Department of Chemistry, Northwestern University, Evanston, Illinois, USA.|Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Omar K
authors.initials: OK
authors.lastname: Farha
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000295:instrumentation / Q000379:methods*; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D016062:Porosity
chemical_list: D009942:Organometallic Compounds