title: Sarcoma and Sarcomatous Metaplastic Carcinoma of the Breast.
abstract: OBJECTIVE
  Primary sarcoma and SMC (sarcomatous metaplastic carcinoma) of the breast are very rare tumors, accounting for less than 1% of all breast malignancies. There are many controversies concerning the biological characteristics, prognosis and optimal treatment of these tumors owing to the rarity of incidence. The aims of this study were to elucidate the clinicopathologic characteristics of these tumors and to assist in elucidating the optimal treatment plan for the disease.
  
  
  METHODS
  13 cases of primary sarcoma and 10 cases of SMC that had been treated at KCCH between 1984 and 2001 were retrospectively reviewed. Phyllodes tumors were excluded from our study.
  
  
  RESULTS
  Among the 13 cases of primary sarcoma included, stromal sarcoma occurred in 5 cases, osteosarcoma in 3 cases, angiosarcoma in 3 cases and spindle cell sarcoma in 2 cases. The mean age of the patients with primary sarcoma and SMC was 39.7 years and 55.1 years respectively (p=0.002). When survival rates were compared according to histologic types, size of tumor, histologic grade, type of surgery and use of adjuvant therapy, both size of tumor (p=0.0256) and histologic grade (p=0.0197) were shown to be prognostic factors.
  
  
  CONCLUSIONS
  There were no significantly different features between primary sarcoma and SMC in terms of biologic characteristics or survival rates, with the exception that patients with SMC were older than those with primary sarcoma. Histologic grade and size of tumor were significant prognostic factors of these tumors.
authors.forename: S H
authors.initials: SH
authors.lastname: Yu
authors.forename: W C
authors.initials: WC
authors.lastname: Noh
authors.forename: H Y
authors.initials: HY
authors.lastname: Bang
authors.forename: D Y
authors.initials: DY
authors.lastname: Hwang
authors.forename: D W
authors.initials: DW
authors.lastname: Choi
authors.forename: J I
authors.initials: JI
authors.lastname: Lee
authors.forename: N S
authors.initials: NS
authors.lastname: Paik
authors.forename: N M
authors.initials: NM
authors.lastname: Moon
authors.forename: J H
authors.initials: JH
authors.lastname: Jung
keywords: Breast neoplasm; Sarcoma; Sarcomatous metaplastic carcinoma