title: Spinal cord infarct as a presentation of cholangiocarcinoma with metastases.
abstract: It is well-known that malignancies, particularly pancreatic and brain cancers, often present as venous thromboembolism. However, stroke and angina attributable to arterial occlusion are relatively common presentations as well. We are reporting a patient, with treatment-naïve hepatitis C and multiple liver nodules, was admitted for deep vein thrombosis (DVT) and pulmonary embolism (PE). Subsequently, she developed an ascending paralysis due to spinal cord infarct (SCI) despite adequate anticoagulation. She also had an enlargement of left supraclavicular lymph node, which was confirmed histologically metastatic cholangiocarcinoma. To our best knowledge, this is the first literature report showing the association linking SCI to metastatic cholangiocarcinoma as a consequence of hypercoagulable state of malignancy.
authors.affiliation: 1 Department of Medicine, Division of Hematology and Oncology, 2 Department of Medicine, 3 Deaprtment of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, USA.
authors.forename: Yu Yu
authors.initials: YY
authors.lastname: Thar
authors.affiliation: 1 Department of Medicine, Division of Hematology and Oncology, 2 Department of Medicine, 3 Deaprtment of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, USA.
authors.forename: Aung Myint
authors.initials: AM
authors.lastname: Tun
authors.affiliation: 1 Department of Medicine, Division of Hematology and Oncology, 2 Department of Medicine, 3 Deaprtment of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, USA.
authors.forename: Tiangui
authors.initials: T
authors.lastname: Huang
authors.affiliation: 1 Department of Medicine, Division of Hematology and Oncology, 2 Department of Medicine, 3 Deaprtment of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, USA.
authors.forename: Sonal
authors.initials: S
authors.lastname: Bordia
authors.affiliation: 1 Department of Medicine, Division of Hematology and Oncology, 2 Department of Medicine, 3 Deaprtment of Pathology, The Brooklyn Hospital Center, Brooklyn, NY, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Guevara
keywords: Cholangiocarcinoma; cancer-associated thrombosis (CAT); spinal cord infarct (SCI)