title: [Risk factors for interictal epileptiform discharges on electroencephalogram in children with spastic hemiplegic cerebral palsy].
abstract: OBJECTIVE
  To investigate the clinical symptoms and features of interictal epileptiform discharges (IED) on electroencephalogram (EEG) in children with spastic hemiplegic cerebral palsy (CP) and to analyze the risk factors for IED.
  
  
  METHODS
  Eighty-three children with spastic hemiplegic CP were recruited, and their clinical data, results of video-electroencephalogram, imaging findings, and cognitive levels were collected. The influencing factors for IED were determined by multiple logistic regression analysis.
  
  
  RESULTS
  The incidence of epilepsy was 13% in children with spastic hemiplegic CP; 34% of these cases had IED. The incidence of epilepsy in children with IED (32%) was significantly higher than that in those without IED (4%) (P<0.01). The incidence of IED in children with complications and brain cortex impairment increased significantly (P<0.01). The incidence of IED varied significantly between patients with different cognitive levels (P<0.01). Brain cortex impairment (OR=11.521) and low cognitive level (OR=2.238)were risk factors for IED in children with spastic hemiplegic CP (P<0.05).
  
  
  CONCLUSIONS
  Spastic hemiplegic CP is often found with IED on EEG, and the incidence of epilepsy is higher in children with IED than in those without IED. Brain cortex impairment and low cognitive level have predictive values for IED in children with spastic hemiplegic CP.
authors.affiliation: Department of Pediatric Neurology, Nanhai Maternity and Children's Hospital, Foshan, Guangdong 528200, China. qianxuguang@163.com.
authors.forename: Su-Yun
authors.initials: SY
authors.lastname: Li
authors.forename: Xu-Guang
authors.initials: XG
authors.lastname: Qian
authors.forename: Yi-Li
authors.initials: YL
authors.lastname: Zhao
authors.forename: Wen-Jie
authors.initials: WJ
authors.lastname: Fu
authors.forename: Xiao-Ru
authors.initials: XR
authors.lastname: Tan
authors.forename: Zhen-Huan
authors.initials: ZH
authors.lastname: Liu
mesh_terms: D002540:Cerebral Cortex / Q000503:physiopathology; D002547:Cerebral Palsy / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006429:Hemiplegia / Q000503:physiopathology*; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D012307:Risk Factors