title: Fatigue Modeling via Mammalian Auditory System for Prediction of Noise Induced Hearing Loss.
abstract: Noise induced hearing loss (NIHL) remains as a severe health problem worldwide. Existing noise metrics and modeling for evaluation of NIHL are limited on prediction of gradually developing NIHL (GDHL) caused by high-level occupational noise. In this study, we proposed two auditory fatigue based models, including equal velocity level (EVL) and complex velocity level (CVL), which combine the high-cycle fatigue theory with the mammalian auditory model, to predict GDHL. The mammalian auditory model is introduced by combining the transfer function of the external-middle ear and the triple-path nonlinear (TRNL) filter to obtain velocities of basilar membrane (BM) in cochlea. The high-cycle fatigue theory is based on the assumption that GDHL can be considered as a process of long-cycle mechanical fatigue failure of organ of Corti. Furthermore, a series of chinchilla experimental data are used to validate the effectiveness of the proposed fatigue models. The regression analysis results show that both proposed fatigue models have high corrections with four hearing loss indices. It indicates that the proposed models can accurately predict hearing loss in chinchilla. Results suggest that the CVL model is more accurate compared to the EVL model on prediction of the auditory risk of exposure to hazardous occupational noise.
authors.affiliation: Department of Electrical and Computer Engineering, Southern Illinois University, Carbondale, IL 62901, USA.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Sun
authors.affiliation: Department of Electrical and Computer Engineering, Southern Illinois University, Carbondale, IL 62901, USA.
authors.forename: Jun
authors.initials: J
authors.lastname: Qin
authors.affiliation: Department of Surgery, School of Medicine, Southern Illinois University, Springfield, IL 62794, USA.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Campbell
mesh_terms: D000818:Animals; D001305:Auditory Fatigue / Q000502:physiology*; D001489:Basilar Membrane / Q000503:physiopathology; D001696:Biomechanical Phenomena; D002682:Chinchilla; D019295:Computational Biology; D004195:Disease Models, Animal; D005072:Evoked Potentials, Auditory; D006317:Hearing Loss, Noise-Induced / Q000209:etiology* / Q000503:physiopathology*; D006801:Humans; D008954:Models, Biological; D009622:Noise / Q000009:adverse effects; D017711:Nonlinear Dynamics; D016273:Occupational Exposure