title: MDV3100: Tritium labeling at high specific activity.
abstract: An efficient method is described to tritiate MDV3100 at high specific activity.
authors.affiliation: PerkinElmer Health Sciences Inc., 940 Winter Street, Waltham, MA 02451, USA.
authors.forename: Chang
authors.initials: C
authors.lastname: Byon
authors.affiliation: Medivation Inc., 525 Market Street, 36th Floor, San Francisco, CA 94105, USA.
authors.forename: Sarvajit
authors.initials: S
authors.lastname: Chakravarty
authors.affiliation: PerkinElmer Health Sciences Inc., 940 Winter Street, Waltham, MA 02451, USA.
authors.forename: Crist N
authors.initials: CN
authors.lastname: Filer
authors.affiliation: Piramal Enterprises Ltd., 1 Nirlon Complex, Goregoan East, Mumbai 400063, India.
authors.forename: Rajendra
authors.initials: R
authors.lastname: Jain
authors.affiliation: PerkinElmer Health Sciences Inc., 940 Winter Street, Waltham, MA 02451, USA.
authors.forename: Mario P
authors.initials: MP
authors.lastname: Maniscalco
mesh_terms: D001549:Benzamides; D007553:Isotope Labeling / Q000379:methods*; D008422:Materials Testing; D009570:Nitriles; D010669:Phenylthiohydantoin / Q000031:analogs & derivatives* / Q000737:chemistry; D066244:Proton Magnetic Resonance Spectroscopy; D011829:Radiation Dosage; D019275:Radiopharmaceuticals / Q000032:analysis / Q000138:chemical synthesis*; D014316:Tritium / Q000032:analysis / Q000737:chemistry*
chemical_list: D001549:Benzamides; D009570:Nitriles; D019275:Radiopharmaceuticals; D014316:Tritium; D010669:Phenylthiohydantoin; C540278:enzalutamide
keywords: Androgen receptor; MDV3100; Tritium; Tritium NMR