title: Health-related quality of life in people with type 1 Diabetes Mellitus: data from the Brazilian Type 1 Diabetes Study Group.
abstract: BACKGROUND
  Type 1 Diabetes Mellitus (Type 1 DM) affects the psychological and emotional well-being of patients and their families. This study aims to evaluate the health- related quality of life (HRQoL) of people with Type 1 DM in Brazil, a country of continental proportions, using the EuroQol questionnaires.
  
  
  METHODS
  This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group, by analyzing EuroQol scores from 3,005 participants with Type 1 DM, in 28 public clinics in Brazil. Data on demography, economical status, chronic complications, glycemic control and lipid profile were also collected.
  
  
  RESULTS
  The assessment of HRQoL by the EuroQol showed that the average score assigned to general health in Brazil is markedly lower than those found in two other Type 1 DM population-based studies conducted in Europe (EQ-VAS from the Netherlands, the United Kingdom and Brazil were 80.8 ± 15.2, 75.1 ± 18.4 and 72.5 ± 22, respectively). Additionally, our data suggest that a better glycemic control could positively impact the HRQoL of people with Type 1 DM, implying that each 1 % reduction in glycated haemoglobin might lead to an increase of 1.5 points in general health status assessed by the EuroQol.
  
  
  CONCLUSIONS
  This is a population-based study evaluating the HRQoL of people with Type 1 DM in Brazil. Our data indicate a worse quality of health of people with Type 1 DM in Brazil in comparison to Europe, and suggest that a better glycemic control could positively impact the HRQoL of these individuals. However, this study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of these people.
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. carol.souza25@hotmail.com.
authors.forename: Ana Carolina Contente
authors.initials: AC
authors.lastname: Braga de Souza
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. felicio.bel@terra.com.br.
authors.forename: João Soares
authors.initials: JS
authors.lastname: Felício
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. camilakoury@hotmail.com.br.
authors.forename: Camila Cavalcante
authors.initials: CC
authors.lastname: Koury
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. joaofelicioabrahaoneto@gmail.com.
authors.forename: João Felício Abrahão
authors.initials: JF
authors.lastname: Neto
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. karemfelicio@yahoo.com.br.
authors.forename: Karem Barbosa
authors.initials: KB
authors.lastname: Miléo
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. drafms@bol.com.br.
authors.forename: Flávia Marques
authors.initials: FM
authors.lastname: Santos
authors.affiliation: Bauru's Diabetics Association, Internal Medicine, Nações Unidas Avenue, 28040, Centro, 17010-130, Bauru, São Paulo, Brazil. carlosnegrato@uol.com.br.
authors.forename: Carlos Antonio
authors.initials: CA
authors.lastname: Negrato
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. anaregina2001@yahoo.com.br.
authors.forename: Ana Regina Bastos
authors.initials: AR
authors.lastname: Motta
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. denissonds@hotmail.com.
authors.forename: Denisson Dias
authors.initials: DD
authors.lastname: Silva
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. tarbage@gmail.com.
authors.forename: Thaís Pontes
authors.initials: TP
authors.lastname: Arbage
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. caroltc94@hotmail.com.
authors.forename: Carolina Tavares
authors.initials: CT
authors.lastname: Carvalho
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. hanaarbrito@gmail.com.
authors.forename: Hana Andrade
authors.initials: HA
authors.lastname: de Rider Brito
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. esyamada@ufpa.br.
authors.forename: Elizabeth Sumi
authors.initials: ES
authors.lastname: Yamada
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. ftrindade@ufpa.br.
authors.forename: Franciane Trindade
authors.initials: FT
authors.lastname: Cunha de Melo
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. fabriresende@yahoo.com.br.
authors.forename: Fabricio de Souza
authors.initials: Fde S
authors.lastname: Resende
authors.affiliation: University Hospital João de Barros Barreto, Federal University of Pará, Endocrinology Division, Mundurucus Street, 4487, Guamá, 66073-000, Belém, Pará, Brazil. julianacferreira@gmail.com.
authors.forename: Juliana Cristina Cardoso
authors.initials: JC
authors.lastname: Ferreira
authors.affiliation: State University of Rio de Janeiro, Diabetes Unit, Boulevard 28 de setembro, 77, Vila Isabel, 20551-030, Rio de Janeiro, Rio de Janeiro, Brazil. mariliabgomes@gmail.com.
authors.forename: Marilia Brito
authors.initials: MB
authors.lastname: Gomes
mesh_terms: D000328:Adult; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology* / Q000523:psychology*; D005260:Female; D006442:Glycated Hemoglobin; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D012189:Retrospective Studies; D018434:Sickness Impact Profile; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D006442:Glycated Hemoglobin