title: MicroRNAs as biomarkers for dental diseases.
abstract: MicroRNAs (miRNAs) are short, noncoding RNAs that act as key regulators of diverse biological processes by mediating translational repression or mRNA degradation of target genes. Recent studies discovered miRNAs in saliva, and these miRNAs are promising candidates for use as biomarkers of dental diseases. In this review, the results of miRNA studies in the dental field are presented, and a brief overview of the current progress, limitations, and perspectives regarding miRNA biomarkers for dental diseases is given.
authors.affiliation: Department of Dentistry, College of Medicine, University of Ulsan and Asan Medical Center, Seoul, Republic of Korea.
authors.forename: Su-Hwan
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Smart Healthcare, Samsung SDS Co., Ltd., Seoul, Republic of Korea.
authors.forename: Su-Yeon
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.
authors.forename: Yong-Moo
authors.initials: YM
authors.lastname: Lee
authors.affiliation: Department of Periodontics, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, 138-736 Seoul, Republic of Korea. Electronic address: periolee@amc.seoul.kr.
authors.forename: Young-Kyoo
authors.initials: YK
authors.lastname: Lee
keywords: Biomarker; Periodontitis; Saliva; microRNA