title: Prolene Canalostenting in Deep Sclerectomy: A Pilot Study.
abstract: OBJECTIVE
  To study the effect of implantation of a 5/0 prolene suture segment inside Schlemm's canal as an adjunct to deep sclerectomy.
  
  
  METHODS
  This was a prospective, interventional case series of nine eyes of six patients with open angle glaucoma. Patients underwent deep sclerectomy with insertion of a segment of 5/0 prolene into Schlemm's canal at the filtration site without suturing. The main outcome measures were: Intraocular pressure (IOP), postoperative interventions, and complications. Ultrasound biomicroscopy of the filtration area as well as the prolene suture was performed at 6 months postoperatively.
  
  
  RESULTS
  Patients were followed for a mean of 8.1 ± 4.5 months. Mean IOP decreased statistically significant from 19 ± 4.2 mmHg preoperatively to 12 mmHg at 15 months postoperatively (P < 0.0001). The number of glaucoma medications was reduced from 3.7 ± 0.7 preoperatively to 0 postoperatively. No postoperative complications were noted. IOP remained in the low teens in all patients out to the last postoperative visit. Yttrium-aluminum-garnet laser goniopuncture was not required in any case.
  
  
  CONCLUSIONS
  Implantation of a 5/0 prolene suture in Schlemm's canal during deep sclerectomy was a safe, cost-effective adjunct to maintain the patency of the intrascleral space and Schlemm's canal thus controlling IOP for 6 months postoperatively.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.
authors.forename: Ahmed Mostafa
authors.initials: AM
authors.lastname: Abdelrahman
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Cairo University, Cairo, Egypt.
authors.forename: Yasmine Mohamed
authors.initials: YM
authors.lastname: El-Sayed
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D016850:Limbus Corneae / Q000601:surgery; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D010865:Pilot Projects; D011126:Polypropylenes; D011183:Postoperative Complications; D011446:Prospective Studies; D012599:Sclerostomy / Q000379:methods*; D015607:Stents; D013537:Sutures; D014065:Tonometry, Ocular; D055815:Young Adult
chemical_list: D011126:Polypropylenes
keywords: Deep Sclerectomy; Nonpenetrating Glaucoma Surgery; Prolene; Schlemm's Canal