title: Microscopy and supporting data for osteoblast integration within an electrospun fibrous network.
abstract: This data article contains data related to the research article entitled "3D imaging of cell interactions with electrospun PLGA nanofiber membranes for bone regeneration" by Stachewicz et al. [1]. In this paper we include additional data showing degradation analysis of poly(d,l-lactide-co-glycolide acid) (PLGA) electrospun fibers in medium and air using fiber diameter distribution histograms. We also describe the steps used in "slice and view" tomography techniques with focused ion beam (FIB) microscopy and scanning electron microscopy (SEM) and detail the image analysis to obtain 3D reconstruction of osteoblast cell integration with electrospun network of fibers. Further supporting data and detailed information on the quantification of cell growth within the electrospun nanofiber membranes is provided.
authors.affiliation: Nanoforce Technology Ltd., Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom ; School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom ; AGH University of Science and Technology, International Centre of Electron Microscopy for Materials Science and Faculty of Metals Engineering and Industrial Computer Science, Al. A. Mickiewicza 30, 30-059 Kraków, Poland.
authors.forename: Urszula
authors.initials: U
authors.lastname: Stachewicz
authors.affiliation: School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom.
authors.forename: Tuya
authors.initials: T
authors.lastname: Qiao
authors.affiliation: Research Centre for Oral Growth and Development, Barts and The London Queen Mary׳s School of Medicine and Dentistry, 4 Newark Street, London E1 2AT, United Kingdom.
authors.forename: Simon C F
authors.initials: SC
authors.lastname: Rawlinson
authors.affiliation: School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom.
authors.forename: Filipe
authors.initials: F
authors.lastname: Veiga Almeida
authors.affiliation: School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom.
authors.forename: Wei-Qi
authors.initials: WQ
authors.lastname: Li
authors.affiliation: Centre for Adult Oral Health, Institute of Dentistry, Queen Mary׳s School of Medicine and Dentistry, Turner Street, Whitechapel, London E1 2AD, United Kingdom.
authors.forename: Michael
authors.initials: M
authors.lastname: Cattell
authors.affiliation: Nanoforce Technology Ltd., Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom ; School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom ; School of Engineering, University of Portsmouth, Portsmouth PO1 3DJ, United Kingdom.
authors.forename: Asa H
authors.initials: AH
authors.lastname: Barber