title: Evaluation of vitamin D levels in women with carpal tunnel syndrome.
abstract: Studies suggest that vitamin D has a role in neuroprotection. We investigated whether vitamin D status is associated with carpal tunnel syndrome. Vitamin D levels were compared between carpal tunnel syndrome women (n = 135) and healthy control women (n = 135) or patients with other upper limb conditions (n = 135). There were no differences in vitamin D levels between the patients with carpal tunnel syndrome and the controls. However, women with carpal tunnel syndrome younger than 50 years old had significantly lower vitamin D levels than age-matched healthy control women (P = 0.023) or patients with other upper limb conditions (P = 0.035). When women with carpal tunnel syndrome and healthy control women were pooled, the incidence of carpal tunnel syndrome was higher in vitamin D deficient women than in non-deficient women, especially in those younger than 50 years. This study suggests a potential link between vitamin D status and the occurrence of carpal tunnel syndrome in women younger than 50 years but causation is not established.
  
  
  METHODS
  Prognostic Level III.
authors.affiliation: Department of Orthopedic Surgery and Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Orthopedic Surgery and Internal Medicine, Seoul National University College of Medicine, Seoul, Korea hsgong@snu.ac.kr.
authors.forename: H S
authors.initials: HS
authors.lastname: Gong
authors.affiliation: Department of Orthopedic Surgery and Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: D H
authors.initials: DH
authors.lastname: Kim
authors.affiliation: Department of Orthopedic Surgery and Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: H S
authors.initials: HS
authors.lastname: Shin
authors.affiliation: Department of Orthopedic Surgery and Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: K M
authors.initials: KM
authors.lastname: Kim
authors.affiliation: Department of Orthopedic Surgery and Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: J
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Orthopedic Surgery and Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: G H
authors.initials: GH
authors.lastname: Baek
mesh_terms: D000328:Adult; D000367:Age Factors; D002349:Carpal Tunnel Syndrome / Q000097:blood* / Q000453:epidemiology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D012737:Sex Factors; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000150:complications* / Q000175:diagnosis
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: Vitamin D; carpal tunnel syndrome