title: Can Serum Glucose Level in Early Admission Predict Outcome in Patients with Severe Head Trauma?
abstract: BACKGROUND
  Traumatic brain injury is a major general health concern. This study aims to evaluate a possible relationship between the serum level of glucose during admission and the outcome of patients with severe traumatic brain injury.
  
  
  METHODS
  In this prospective study, 80 patients with severe traumatic brain injury were recruited from the emergency department of Urmia Imam Khomeini Hospital. Serum level of glucose was measured at the time of admission and its correlation was investigated with the Glasgow Coma Scale score (on admission, 24 hours, 48 hours, and 1 week later, and at discharge) and Glasgow Outcome Score. In addition, the value of admission serum glucose was compared between deceased and discharged patients.
  
  
  RESULTS
  Eighty patients with severe head trauma, 71 men (88%) and 9 women (11.2%) with a mean age of 31.71 ± 15.66 years, were enrolled into the study. The in-hospital mortality rate was 25% (n = 20). There was no significant correlation between serum glucose level and Glasgow Coma Scale score (at different intervals) or Glasgow Outcome Score. The mean serum level of glucose was comparable between deceased and discharged patients (186.10 ± 51.36 vs. 187.98 ± 76.03 mg/dL, respectively; P = 0.91).
  
  
  CONCLUSIONS
  Admission serum glucose is not a significant indicator of outcome in patients with severe head trauma.
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: Firooz
authors.initials: F
authors.lastname: Salehpour
authors.affiliation: Department of Neurosurgery, Tabriz Alinasab Hospital, Tabriz, Iran.
authors.forename: Amir Mohammad
authors.initials: AM
authors.lastname: Bazzazi
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: Javad
authors.initials: J
authors.lastname: Aghazadeh
authors.affiliation: Department of Anesthesiology, Urmia University of Medical Sciences, Urmia, Iran.
authors.forename: Rahman
authors.initials: R
authors.lastname: Abbasivash
authors.affiliation: Urmia University of Medical Sciences, Urmia, Iran.
authors.forename: Yalda
authors.initials: Y
authors.lastname: Forouhideh
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: Farhad
authors.initials: F
authors.lastname: Mirzaei
authors.affiliation: Tabriz University of Medical Sciences, Faculty of Medicine, Tabriz, Iran. Electronic address: dr.arsalan2010@gmail.com.
authors.forename: Seyed Ahmad
authors.initials: SA
authors.lastname: Naseri Alavi
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism*; D006259:Craniocerebral Trauma / Q000097:blood* / Q000401:mortality / Q000503:physiopathology; D003643:Death; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D010351:Patient Discharge; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies
chemical_list: D015415:Biomarkers; D001786:Blood Glucose
keywords: Serum glucose level; Severe head trauma; Trauma; Traumatic brain injury