title: The relationship of severe health disorders with bone loss, grip strength, and mobility in postmenopausal women - a 15-year follow-up study.
abstract: To investigate the relationships of severe health disorders (SHD) with bone loss, grip strength (GS) and mobility in postmenopausal women.
  
  
  
  The study sample consisted of 2227 Finnish women (mean age 53.2) from the Kuopio Osteoporosis Risk Factor and Prevention (OSTPRE) cohort. Postal inquiries and clinical measurements were completed during the 15-year follow-up at 5-year intervals between 1989 and 2004. Femoral neck bone mineral density (BMD) and GS were measured. Life-style factors and mobility were obtained via postal inquiries. Work disability pension according to the ICD-9 was an indicator of a SHD.
  
  
  
  At the baseline 242 women had SHD, 506 got late SHD during 1989-1995, whereas 1479 women had none until 1996. The women with baseline SHD had higher annual bone loss (0.44%) than those without SHD (0.34%) (p < 0.05), those with late SHD (0.39%) no difference was seen. Bone loss was highest with respiratory diseases, but BMD was lowest throughout the follow-up in nervous and sense organ diseases. Lower GS and mobility was also associated with SHD.
  
  
  
  Effects of SHDs on BMD, GS, and mobility are disease-specific. Thus, rehabilitation should be encouraged in postmenopausal women with SHD, especially in case of diseases of respiratory and nervous system. Implications for Rehabilitation Osteoporosis, muscle strength and co-morbidity Women with severe health disorders (SHD) leading to work disability have impaired musculoskeletal health. Active monitoring of the musculoskeletal health is advised for those with SHD. Women with SHD may benefit from rehabilitative treatment in order to avoid complications of musculoskeletal impairments.
authors.affiliation: a Kuopio Musculoskeletal Research Unit (KMRU) , Institute of Clinical Medicine, University of Eastern Finland , Kuopio , Finland.
authors.forename: Juha
authors.initials: J
authors.lastname: Suuronen
authors.affiliation: a Kuopio Musculoskeletal Research Unit (KMRU) , Institute of Clinical Medicine, University of Eastern Finland , Kuopio , Finland.
authors.forename: Samu
authors.initials: S
authors.lastname: Sjöblom
authors.affiliation: a Kuopio Musculoskeletal Research Unit (KMRU) , Institute of Clinical Medicine, University of Eastern Finland , Kuopio , Finland.
authors.forename: Risto
authors.initials: R
authors.lastname: Honkanen
authors.affiliation: b Department of Psychiatry, Institute of Clinical Psychiatry , University of Eastern Finland , Kuopio , Finland.|c Kuopio University Hospital, South-Savonia Hospital District , Mikkeli , Finland.|d North Karelia Central Hospital , Joensuu , Finland.|e SOSTERI , Savonlinna , Finland.|f SOTE , Iisalmi , Finland.|g Lapland Hospital District , Rovaniemi , Finland.|h Clinic of Child Psychiatry , Oulu University Hospital , Oulu , Finland.
authors.forename: Heli
authors.initials: H
authors.lastname: Koivumaa-Honkanen
authors.affiliation: a Kuopio Musculoskeletal Research Unit (KMRU) , Institute of Clinical Medicine, University of Eastern Finland , Kuopio , Finland.|i Department of Orthopaedics, Traumatology and Hand Surgery , Kuopio University Hospital , Kuopio , Finland.
authors.forename: Heikki
authors.initials: H
authors.lastname: Kröger
authors.affiliation: a Kuopio Musculoskeletal Research Unit (KMRU) , Institute of Clinical Medicine, University of Eastern Finland , Kuopio , Finland.|i Department of Orthopaedics, Traumatology and Hand Surgery , Kuopio University Hospital , Kuopio , Finland.
authors.forename: Joonas
authors.initials: J
authors.lastname: Sirola
authors.affiliation: a Kuopio Musculoskeletal Research Unit (KMRU) , Institute of Clinical Medicine, University of Eastern Finland , Kuopio , Finland.
authors.forename: Toni
authors.initials: T
authors.lastname: Rikkonen
mesh_terms: D015502:Absorptiometry, Photon; D015519:Bone Density; D002908:Chronic Disease / Q000534:rehabilitation*; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D018737:Hand Strength; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D051346:Mobility Limitation; D053580:Muscle Strength / Q000502:physiology*; D015663:Osteoporosis, Postmenopausal / Q000503:physiopathology*; D017698:Postmenopause; D012307:Risk Factors; D011795:Surveys and Questionnaires
keywords: Co-morbidity; disability leave; disability pension; grip strength; osteoporosis; postmenopause