title: Small data sets to develop and validate prognostic models are problematic.
authors.affiliation: Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Windmill Road, Oxford OX3 7LD, United Kingdom. Electronic address: gary.collins@csm.ox.ac.uk.
authors.forename: Gary S
authors.initials: GS
authors.lastname: Collins
authors.affiliation: Departments of Anesthesia & Clinical Epidemiology and Biostatistics, Michael DeGroote School of Medicine, Faculty of Health Sciences, McMaster University and the Perioperative Research Group, Population Health Research Institute, Hamilton, Canada.
authors.forename: Yannick
authors.initials: Y
authors.lastname: Le Manach
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003661:Decision Support Techniques; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000556:secondary*; D057285:Precision Medicine; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology*
chemical_list: D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents