title: Comparison of pediatric radiation dose and vessel visibility on angiographic systems using piglets as a surrogate: antiscatter grid removal vs. lower detector air kerma settings with a grid - a preclinical investigation.
abstract: The purpose of this study was to reduce pediatric doses while maintaining or improv-ing image quality scores without removing the grid from X-ray beam. This study was approved by the Institutional Animal Care and Use Committee. Three piglets (5, 14, and 20 kg) were imaged using six different selectable detector air kerma (Kair) per frame values (100%, 70%, 50%, 35%, 25%, 17.5%) with and without the grid. Number of distal branches visualized with diagnostic confidence relative to the injected vessel defined image quality score. Five pediatric interventional radiologists evaluated all images. Image quality score and piglet Kair were statistically compared using analysis of variance and receiver operating curve analysis to define the preferred dose setting and use of grid for a visibility of 2nd and 3rd order vessel branches. Grid removal reduced both dose to subject and imaging quality by 26%. Third order branches could only be visualized with the grid present; 100% detector Kair was required for smallest pig, while 70% detector Kair was adequate for the two larger pigs. Second order branches could be visualized with grid at 17.5% detector Kair for all three pig sizes. Without the grid, 50%, 35%, and 35% detector Kair were required for smallest to largest pig, respectively. Grid removal reduces both dose and image quality score. Image quality scores can be maintained with less dose to subject with the grid in the beam as opposed to removed. Smaller anatomy requires more dose to the detector to achieve the same image quality score.
authors.affiliation: Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine. keith.strauss@cchmc.org.
authors.forename: Keith J
authors.initials: KJ
authors.lastname: Strauss
authors.forename: John M
authors.initials: JM
authors.lastname: Racadio
authors.forename: Todd A
authors.initials: TA
authors.lastname: Abruzzo
authors.forename: Neil D
authors.initials: ND
authors.lastname: Johnson
authors.forename: Manish N
authors.initials: MN
authors.lastname: Patel
authors.forename: Kamlesh U
authors.initials: KU
authors.lastname: Kukreja
authors.forename: Mark J H
authors.initials: MJ
authors.lastname: den Hartog
authors.forename: Bart P A
authors.initials: BP
authors.lastname: Hoonaert
authors.forename: Rami A
authors.initials: RA
authors.lastname: Nachabe
mesh_terms: D000792:Angiography; D000818:Animals; D002675:Child, Preschool; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted; D012542:Scattering, Radiation; D013552:Swine; D014965:X-Rays