title: The Janus face of myofibroblasts in the remodeling heart.
authors.affiliation: Dept. of Pharmacology and Toxicology, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands.
authors.forename: Kevin C M
authors.initials: KC
authors.lastname: Hermans
authors.affiliation: Pôle de Recherche Cardiovasculaire (CARD) Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Brussels, Belgium; Cardiovascular Research (Care) Institute, Athens & Ioannina, Greece.
authors.forename: Evangelos P
authors.initials: EP
authors.lastname: Daskalopoulos
authors.affiliation: Dept. of Pharmacology and Toxicology, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands. Electronic address: wm.blankesteijn@maastrichtuniversity.nl.
authors.forename: W Matthijs
authors.initials: WM
authors.lastname: Blankesteijn
mesh_terms: D000199:Actins / Q000235:genetics / Q000378:metabolism; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D056668:Cathepsin L / Q000235:genetics / Q000378:metabolism; D002454:Cell Differentiation; D042783:Endothelial Cells / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D004847:Epithelial Cells / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D005355:Fibrosis / Q000517:prevention & control; D005786:Gene Expression Regulation; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D009203:Myocardial Infarction / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D009206:Myocardium / Q000378:metabolism / Q000473:pathology*; D058628:Myofibroblasts / Q000187:drug effects / Q000378:metabolism / Q000473:pathology*; D000683:Serum Amyloid P-Component / Q000627:therapeutic use; D015398:Signal Transduction
chemical_list: C541116:ACTA2 protein, human; D000199:Actins; D000683:Serum Amyloid P-Component; C534281:CTSL protein, human; D056668:Cathepsin L
keywords: cardiac fibrosis; epithelial-to-mesenchymal transition; fibrocyte; mesenchymal stem cell; myofibroblast; signaling