title: [A Case of Urachal Carcinoma Treated by TS-1/CDDP as Adjuvant Chemotherapy].
abstract: A 49-year-old female presented complaining of gross hematuria. Cystoscopy and magnetic resonance imaging revealed a papillary tumor on the bladder dome. At biopsy pathology the tumor was diagnosed as adenocarcinoma. We diagnosed the tumor as urachal adenocarcinoma and performed partial cystectomy of bladder dome with en-bloc resection of the urachal ligament up to the umbilicus. In surgical pathology, the tumor had invaded to the fat tissue around the urachal ligament with metastasis to the lymph node. Therefore the tumor was diagnosed as a stage IVA (Sheldon's category) urachal adenocarcinoma. After surgery, 6 cycles of chemotherapy with TS-1 and cisplatin (CDDP) were performed. There has been no relapse 5 years after surgery. This is the first report of successful adjuvant chemotherapy with TS-1/CDDP for advanced urachal adenocarcinoma.
authors.affiliation: The Department of Urology, Showa University Northern Yokohama Hospital.
authors.forename: Katsuki
authors.initials: K
authors.lastname: Inoue
authors.affiliation: The Department of Urology, Showa University Northern Yokohama Hospital.
authors.forename: Makoto
authors.initials: M
authors.lastname: Shimada
authors.affiliation: The Department of Urology, Showa University Northern Yokohama Hospital.
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Saito
authors.affiliation: The Department of Urology, Showa University Northern Yokohama Hospital.
authors.forename: Yuuichiro
authors.initials: Y
authors.lastname: Ogawa
authors.affiliation: The Department of Urology, Showa University Northern Yokohama Hospital.
authors.forename: Eiji
authors.initials: E
authors.lastname: Matsubara
authors.affiliation: The Department of Urology, Showa University Northern Yokohama Hospital.
authors.forename: Yuuki
authors.initials: Y
authors.lastname: Matsumoto
authors.affiliation: The Department of Urology, Showa University Northern Yokohama Hospital.
authors.forename: Hayashi
authors.initials: H
authors.lastname: Keiichiro
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D015653:Cystectomy; D003558:Cystoscopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D017640:Silicates / Q000008:administration & dosage; D014025:Titanium / Q000008:administration & dosage; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000601:surgery
chemical_list: D017640:Silicates; C103828:titanium silicide; D014025:Titanium; D002945:Cisplatin