title: Variable mechanism of nucleophilic substitution of P-stereogenic phosphoryl chloride with alkynyl metallic reagents.
abstract: The variable mechanism for substitution of P-stereogenic phosphoryl chloride with alkynyl metallic reagents, which depends on temperature, stoichiometry of starting materials, and the structure of the nucleophilic reagent, is assumed as either SN2-like or Berry pseudorotation of pentacoordinated phosphorus intermediates, affording inversion and retention products, respectively. The formation of the inversion product can be controlled to occur predominantly to afford (RP)-alkynylphosphinates.
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, China. literabc@hotmail.com.
authors.forename: Lan
authors.initials: L
authors.lastname: Yao
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, China. literabc@hotmail.com.
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Liu
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, China. literabc@hotmail.com.
authors.forename: Zhong-Yuan
authors.initials: ZY
authors.lastname: Xu
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, China. literabc@hotmail.com.
authors.forename: Shao-Zhen
authors.initials: SZ
authors.lastname: Nie
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, China. literabc@hotmail.com.
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Xiao
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, China. literabc@hotmail.com.
authors.forename: Chang-Qiu
authors.initials: CQ
authors.lastname: Zhao