title: Impact of Clinical Pharmacy Services on KAP and QOL in Cancer Patients: A Single-Center Experience.
abstract: This study was to evaluate the efficacy of pharmaceutical intervention (PI) on chemotherapy knowledge-attitude-practice (KAP) and quality of life (QOL) in cancer patients. A prospective, randomized, controlled study was carried out at Oncology Ward in a tertiary hospital affiliated to Southern Medical University, China. Eligible patient was randomly assigned to pharmaceutical intervention (PI) group or control group. Each patient in PI group was given information booklets and was given 30 min face-to-face medication education and psychological counseling by clinical pharmacists, 2 sessions per week for 2 months. Patients in control group only received conventional treatment. All participants were asked to complete a structured Chemotherapy KAP Questionnaire and QOL Questionnaire at pre- and poststudy time. A total of 149 cancer patients (77 in PI group and 72 in control group) completed the study. The baseline scores of KAP and QOL in 2 groups were similar. At the end of study, only knowledge score was significantly increased; meanwhile no difference existed for attitude, practice, and QOL scores in control group; both KAP scores and QOL score were significantly increased in PI group. As for the between-group comparison, both KAP scores and QOL score in PI group were significantly higher than those in control group. In conclusion, pharmaceutical intervention has a positive role in increasing chemotherapy-related knowledge, improving patients' positive emotions, dealing with chemotherapy adverse reactions, and improving the quality of life of patients.
authors.affiliation: Department of Pharmacy, Fengxian Hospital, Southern Medical University, Shanghai 201400, China ; Department of Pharmacy, Guangdong Medical University Affiliated Hospital, Zhanjiang 524001, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Pharmacy, Fengxian Hospital, Southern Medical University, Shanghai 201400, China.
authors.forename: Huimin
authors.initials: H
authors.lastname: Wu
authors.affiliation: Department of Pharmacy, Fengxian Hospital, Southern Medical University, Shanghai 201400, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
mesh_terms: D000328:Adult; D000368:Aged; D002681:China; D005260:Female; D006266:Health Education; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy* / Q000453:epidemiology* / Q000473:pathology; D010607:Pharmacy Service, Hospital; D011788:Quality of Life; D011795:Surveys and Questionnaires