title: Differentiating Aging Among Adults With Down Syndrome and Comorbid Dementia or Psychopathology.
abstract: Differences were examined between three groups of adults with Down syndrome in their behavioral presentation, social life/activities, health, and support needs. We compared those with comorbid dementia, with comorbid psychopathology, and with no comorbid conditions. Adults with comorbid dementia were more likely to be older, have lower functional abilities, have worse health and more health conditions, and need more support in self-care. Adults with comorbid psychopathology were more likely to exhibit more behavior problems and to be living at home with their families. Adults with no comorbidities were most likely to be involved in community employment. Differences in behavioral presentation can help facilitate clinical diagnoses in aging in Down syndrome, and implications for differential diagnosis and service supports are discussed.
authors.affiliation: Anna J. Esbensen, Emily Boshkoff Johnson, Joseph L. Amaral, Christine M. Tan, and Ryan Macks, Cincinnati Children's Hospital Medical Center.
authors.forename: Anna J
authors.initials: AJ
authors.lastname: Esbensen
authors.affiliation: Anna J. Esbensen, Emily Boshkoff Johnson, Joseph L. Amaral, Christine M. Tan, and Ryan Macks, Cincinnati Children's Hospital Medical Center.
authors.forename: Emily Boshkoff
authors.initials: EB
authors.lastname: Johnson
authors.affiliation: Anna J. Esbensen, Emily Boshkoff Johnson, Joseph L. Amaral, Christine M. Tan, and Ryan Macks, Cincinnati Children's Hospital Medical Center.
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Amaral
authors.affiliation: Anna J. Esbensen, Emily Boshkoff Johnson, Joseph L. Amaral, Christine M. Tan, and Ryan Macks, Cincinnati Children's Hospital Medical Center.
authors.forename: Christine M
authors.initials: CM
authors.lastname: Tan
authors.affiliation: Anna J. Esbensen, Emily Boshkoff Johnson, Joseph L. Amaral, Christine M. Tan, and Ryan Macks, Cincinnati Children's Hospital Medical Center.
authors.forename: Ryan
authors.initials: R
authors.lastname: Macks
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000523:psychology*; D015897:Comorbidity; D003704:Dementia / Q000453:epidemiology; D004314:Down Syndrome / Q000453:epidemiology / Q000451:nursing / Q000523:psychology; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology; D008875:Middle Aged
keywords: Down syndrome; aging; dementia; psychopathology