title: Clinical-psychological characteristics of refractory globus patients in China.
abstract: BACKGROUND
  Refractory globus is not rare in clinical practice, but little research about it.
  
  
  OBJECTIVE
  To investigate the clinical-psychological characteristics of patients with refractory globus.
  
  
  METHODS
  Six hundred and nineteen globus patients were divided into the refractory globus group (n=149) and the non-refractory globus group (n=470). All subjects completed the following questionnaires: demographic characteristics, medical information, Hamilton Rating Scale of Anxiety/Depression, Pittsburgh Sleep Quality Index, Glasgow Edinburgh Throat Scale, and 36-item Short Form Health Survey.
  
  
  RESULTS
  No significantly differences were found in demographic characteristics between the two groups, but the refractory globus group had longer disease duration and more serious symptoms. Sought healthcare more frequently but still had poorer quality of life than did the non-refractory globus group. Compared with the non-refractory globus group, the refractory globus group also had higher percentages of anxiety, depression, and sleep disorders. Positive correlations were observed between the severity of globus symptoms and HAMA, HAMD, and PSQI scores.
  
  
  CONCLUSIONS
  Refractory globus is not rare in clinical practice and should receive more attention from patients and doctors because of its severe symptoms, long disease duration, poor quality of life, and accompanied by psychological disorders and sleep disorders.
authors.affiliation: Department of Gastroenterology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
authors.forename: Bei
authors.initials: B
authors.lastname: Tang
authors.affiliation: Department of Gastroenterology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China; Department of Gastroenterology, Guangzhou Nansha Central Hospital affiliated with Guangzhou First People's Hospital, Guangzhou, Guangdong Province, China. Electronic address: 13925012853@139.com.
authors.forename: Lin
authors.initials: L
authors.lastname: Jia
authors.affiliation: Department of Gastroenterology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China; Department of Gastroenterology, Guangzhou Nansha Central Hospital affiliated with Guangzhou First People's Hospital, Guangzhou, Guangdong Province, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Gastroenterology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Gu
authors.affiliation: Department of Psychology, Guangzhou Nansha Central Hospital affiliated with Guangzhou First People's Hospital, Guangzhou, Guangdong Province, China.
authors.forename: Hai-Xia
authors.initials: HX
authors.lastname: Ye
authors.affiliation: Department of Otorhinolaryngology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
authors.forename: Jiang-Shun
authors.initials: JS
authors.lastname: Song
authors.affiliation: Department of Otorhinolaryngology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Su
authors.affiliation: Department of Otorhinolaryngology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
authors.forename: Xiao-Bing
authors.initials: XB
authors.lastname: Ji
authors.affiliation: Department of Otorhinolaryngology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong Province, China.
authors.forename: Jin-Hua
authors.initials: JH
authors.lastname: Xie
authors.affiliation: Department of Otorhinolaryngology, Guangdong No. 2 Provincial People's Hospital, Guangzhou, Guangdong Province, China.
authors.forename: Xue-Hui
authors.initials: XH
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000453:epidemiology*; D002681:China; D003291:Conversion Disorder / Q000523:psychology*; D003863:Depression / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000453:epidemiology*; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Psychological disorders; Quality of life; Quality of sleep; Refractory globus