title: Plasmacytoma of the testis in a patient with relapsed and refractory multiple myeloma: Case report and review of the literature.
abstract: Testicular plasmacytoma, whether occurring as a primary lesion or as a reflection of underlying multiple myeloma (MM), is a rare disease. We report the case of a 38-year-old male with multiply relapsed MM, who was found to have a testicular plasmacytoma. He presented with a gradually enlarging scrotal mass. Following orchidectomy, pathologic examination of the specimen demonstrated a plasmacytoma. In the context of active MM, the specimen was also sent for cytogenetic analysis but this was unhelpful in guiding a chemotherapy regime, which still continues at time of reporting. Although a rare lesion, there remains no definitive treatment protocol for the management of testicular plasmacytoma representing an extramedullary manifestation of MM.
authors.affiliation: Department of Surgery, University of Melbourne, Austin Hospital, Melbourne, Australia.
authors.forename: Munad
authors.initials: M
authors.lastname: Khan
authors.affiliation: Department of Surgery, University of Melbourne, Austin Hospital, Melbourne, Australia.
authors.forename: Nieroshan
authors.initials: N
authors.lastname: Rajarubendra
authors.affiliation: Department of Surgery, University of Melbourne, Austin Hospital, Melbourne, Australia.
authors.forename: Sarah
authors.initials: S
authors.lastname: Azer
authors.affiliation: Department of Pathology, Austin Hospital, Melbourne, Australia.
authors.forename: Alison
authors.initials: A
authors.lastname: Skene
authors.affiliation: Department of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia ; Department of Oncology, Sir Peter MacCallum, University of Melbourne, Melbourne, Australia.
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Harrison
authors.affiliation: Department of Oncology, Sir Peter MacCallum, University of Melbourne, Melbourne, Australia ; Department of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Australia.
authors.forename: Belinda
authors.initials: B
authors.lastname: Campbell
authors.affiliation: Department of Surgery, University of Melbourne, Austin Hospital, Melbourne, Australia ; Olivia Newton-John Cancer Research Department, Austin Hospital, Melbourne, Australia ; Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Australia.
authors.forename: Nathan
authors.initials: N
authors.lastname: Lawrentschuk
keywords: Extramedullary plasmacytoma; multiple myeloma; plasmacytoma; testis