title: Transcatheter aortic valve replacement: History and current indications.
abstract: Transcatheter aortic valve replacement is an effective way to treat patients with symptomatic severe aortic valve stenosis who are deemed high risk or inoperable. Current data suggest that the mortality and stroke rates are acceptable compared to surgical aortic valve replacement. There is a possible utility in moderate-risk patients as more data become available.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH, USA. E-mail: zeeshaa@ccf.org.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Zeeshan
authors.affiliation: Vice Chairman, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA.|Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: E Murat
authors.initials: EM
authors.lastname: Tuzcu
authors.affiliation: Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Amar
authors.initials: A
authors.lastname: Krishnaswamy
authors.affiliation: Section Head, Invasive/Interventional Cardiology, Cleveland Clinic, Cleveland, OH, USA.|Director, Sones Cardiac Catheterization Laboratories, Cleveland Clinic, Cleveland, OH, USA.|Director, Interventional Cardiology Fellowship Program, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA.|Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Samir
authors.initials: S
authors.lastname: Kapadia
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Mick
mesh_terms: D000818:Animals; D001024:Aortic Valve Stenosis / Q000601:surgery*; D002986:Clinical Trials as Topic; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008953:Models, Anatomic; D065467:Transcatheter Aortic Valve Replacement / Q000266:history / Q000379:methods*