title: Primary Bilateral Non-Hodgkin's Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses.
abstract: Although lymphoma may occasionally involve the adrenal glands as part of a generalized disease process, primary adrenal lymphoma (PAL) is a rare disease. We present a case of a 62-year-old woman with a history of mild/moderate hereditary spherocytosis with a well-compensated baseline haemoglobin, who presented with rapidly progressive symptomatic anaemia. During the diagnostic workup, imaging revealed bilateral large adrenal masses and she was later diagnosed with diffuse large B-cell non-Hodgkin's lymphoma (DLBCL), with the adrenal glands being the dominant site of the disease. The patient was started on systemic chemotherapy, but her disease progressed with neurological involvement which responded to second-line therapy. Her adrenal disease however was refractory to further therapy.
authors.affiliation: Diabetes and Endocrine Centre, Mater Dei Hospital, Msida MSD 2090, Malta ; Department of Medicine, University of Malta Medical School, Msida MSD 2080, Malta.
authors.forename: Christopher
authors.initials: C
authors.lastname: Rizzo
authors.affiliation: Department of Haemato-Oncology, Mater Dei Hospital, Msida MSD 2090, Malta.
authors.forename: David James
authors.initials: DJ
authors.lastname: Camilleri
authors.affiliation: Histopathology Section, Pathology Department, Mater Dei Hospital, Msida MSD 2090, Malta.
authors.forename: Alexandra
authors.identifier: 0000-0003-0690-4257
authors.initials: A
authors.lastname: Betts
authors.affiliation: Medical Imaging Department, Mater Dei Hospital, Msida MSD 2090, Malta.
authors.forename: Andre'
authors.initials: A
authors.lastname: Gatt
authors.affiliation: Diabetes and Endocrine Centre, Mater Dei Hospital, Msida MSD 2090, Malta ; Department of Medicine, University of Malta Medical School, Msida MSD 2080, Malta.
authors.forename: Stephen
authors.identifier: 0000-0002-2372-7101
authors.initials: S
authors.lastname: Fava