title: [Cornual pregnancy: Management and subsequent fertility].
abstract: OBJECTIVE
  Cornual pregnancy is a rare entity, representing 2% of ectopic pregnancies. Its management is poorly codified and often guided by the clinical situation. The aim of our study was to describe the management of cornual pregnancies, subsequent fertility, and obstetric outcomes according to the management.
  
  
  METHODS
  Observational retrospective unicentric study. Nineteen patients hospitalized for cornual pregnancy between 2006 and 2015 were included. The data was collected with medical records and a phone standardized questionnaire. Patients were managed according to hemodynamic status by either systemic or local methotrexate injection or surgical corneal resection.
  
  
  RESULTS
  Among the 19 patients, 32% (6) were treated by systemic injection (one failure treated by surgical treatment) and 68% (13) underwent surgical treatment by cornual resection. The median HCG rate decrease was 33 days (16-62). Among the twelve patients with a desire for a new pregnancy, 7 (58%) became pregnant without assisted reproductive technology (2 following medical treatment and 5 following surgical resection). Histological analysis of uterine horn showed proximal fallopian tube lesions in 76.9% of case (chronic salpingitis, endosalpingiosis and adenomyosis).
  
  
  CONCLUSIONS
  Cornual pregnancies are at high risk of hemorrhagic rupture. Ectopic recidive may occur. Fertility and obstetrical outcomes following cornual pregnancy are not affected whatever the initial treatment. Other studies are needed to aid clinical management according to HCG level and ultrasound features.
authors.affiliation: Service de gynécologie-obstétrique, université Paris XIII-Bobigny, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France.
authors.forename: K
authors.initials: K
authors.lastname: Nikodijevic
authors.affiliation: Service de gynécologie-obstétrique, université Paris XIII-Bobigny, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France.
authors.forename: A
authors.initials: A
authors.lastname: Bricou
authors.affiliation: Service de gynécologie-obstétrique, université Paris XIII-Bobigny, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France.
authors.forename: A
authors.initials: A
authors.lastname: Benbara
authors.affiliation: Service de gynécologie-obstétrique, université Paris XIII-Bobigny, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France.
authors.forename: G
authors.initials: G
authors.lastname: Moreaux
authors.affiliation: Service de gynécologie-obstétrique, université Paris XIII-Bobigny, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris cité, UFR SMBH, 93140 Bobigny, France.
authors.forename: C
authors.initials: C
authors.lastname: Nguyen
authors.affiliation: Service de gynécologie-obstétrique, université Paris XIII-Bobigny, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris cité, UFR SMBH, 93140 Bobigny, France.
authors.forename: L
authors.initials: L
authors.lastname: Carbillon
authors.affiliation: Service de gynécologie-obstétrique, université Paris XIII-Bobigny, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris cité, UFR SMBH, 93140 Bobigny, France.
authors.forename: C
authors.initials: C
authors.lastname: Poncelet
authors.affiliation: Service de gynécologie-obstétrique, université Paris XIII-Bobigny, CHU Jean-Verdier, avenue du 14-Juillet, 93140 Bondy, France; Université Paris 13, Sorbonne Paris cité, UFR SMBH, 93140 Bobigny, France. Electronic address: jeremy.boujenah@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Boujenah
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal; D000328:Adult; D005260:Female; D005298:Fertility; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage; D011247:Pregnancy; D065173:Pregnancy, Cornual / Q000188:drug therapy* / Q000601:surgery*; D012189:Retrospective Studies
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate
keywords: Cornual; Ectopic pregnancy; Fertility; Fertilité; Grossesse extra-utérine; Management; Prise en charge