title: Oral microbiome, periodontitis and risk of head and neck cancer.
abstract: A wide range of studies has been successfully exploring the association between the human microenvironment, sustained inflammation, and cancer. Growing evidence has then emerged in this field over the past few years. Nevertheless, reliable data addressing the impact of the oral microbiome and periodontitis on the pathogenesis and risk of head and neck malignancies remain scarce. Hence, this communication focuses on briefly discuss the relationship between the oral microbiome, periodontitis and head and neck cancer based on the current understanding of such a disease-associated scenario.
authors.affiliation: School of Medicine, Federal University of Maranhão, São Luís, Brazil.
authors.forename: Leonardo Victor
authors.initials: LV
authors.lastname: Galvão-Moreira
authors.affiliation: Department of Dentistry II, Federal University of Maranhão, São Luís, Brazil. Electronic address: ma.carmen@uol.com.br.
authors.forename: Maria Carmen Fontoura Nogueira
authors.initials: MC
authors.lastname: da Cruz
mesh_terms: D006258:Head and Neck Neoplasms / Q000150:complications / Q000382:microbiology*; D006801:Humans; D064307:Microbiota; D009061:Mouth Mucosa / Q000382:microbiology*; D010518:Periodontitis / Q000150:complications / Q000382:microbiology*; D016966:Porphyromonas gingivalis / Q000472:pathogenicity*; D016388:Tooth Loss / Q000150:complications
keywords: Cancer; Dental care; Head and neck neoplasms; Inflammation; Microbiota; Periodontitis; Tooth loss