title: A matched cohort analysis of single anastomosis loop duodenal switch versus Roux-en-Y gastric bypass with 18-month follow-up.
abstract: The Roux-en-Y gastric bypass (GBP) has been considered the gold standard for many years. The loop duodenal switch (LDS) is a relatively new procedure that simplifies the complexity of the duodenal switch (BPDDS) by making it a single anastomosis procedure while at the same time giving it more intestinal absorption to reduce the rates of malnutrition associated with traditional BPDDS. This paper seeks to compare the 18-month weight loss outcomes and complications of the more standard GBP with the newer LDS in a single US center.
  
  
  
  A retrospective matched cohort was analyzed on 108 patients who had either GBP (54 patients) or LDS (54 patients). Regression analysis was used to compare weight loss outcomes as measured by BMI and weight loss percentages. Complications gathered included bleeds, reoperations, diagnostic or therapeutic endoscopy (EGD), ulcers and chronic nausea.
  
  
  
  GBP and LDS have statistically similar weight loss at 18 months (39.6 vs 41 % weight loss, respectively). However, there were significantly more nausea complaints (26 vs 5), diagnostic endoscopies (EGD) (21 vs 3) and ulcers (6 vs 0) with the GBP than the LDS.
  
  
  
  LDS has comparable weight loss results to GBP. However, LDS has fewer 30-day and 18-month complications and patients suffer from less nausea postoperatively.
authors.affiliation: Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT, 84102, USA.
authors.forename: Austin
authors.initials: A
authors.lastname: Cottam
authors.affiliation: Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT, 84102, USA. drdanielcottam@yahoo.com.
authors.forename: Daniel
authors.initials: D
authors.lastname: Cottam
authors.affiliation: Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT, 84102, USA.
authors.forename: Walter
authors.initials: W
authors.lastname: Medlin
authors.affiliation: Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT, 84102, USA.
authors.forename: Christina
authors.initials: C
authors.lastname: Richards
authors.affiliation: Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT, 84102, USA.
authors.forename: Samuel
authors.initials: S
authors.lastname: Cottam
authors.affiliation: Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT, 84102, USA.
authors.forename: Hinali
authors.initials: H
authors.lastname: Zaveri
authors.affiliation: Bariatric Medicine Institute, 1046 East 100 South, Salt Lake City, UT, 84102, USA.
authors.forename: Amit
authors.initials: A
authors.lastname: Surve
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods*; D015331:Cohort Studies; D004386:Duodenum / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D015390:Gastric Bypass; D006801:Humans; D010535:Laparoscopy; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery; D011183:Postoperative Complications; D012189:Retrospective Studies; D015431:Weight Loss
keywords: Endoscopies; Loop duodenal switch; Match cohort; Nausea; Roux-en-Y gastric bypass