title: Non-Trigger Anesthesia Management in a Patient With Leigh's Syndrome Presenting for Dental Rehabilitation.
abstract: BACKGROUND
  Usually presenting in infancy, Leigh's syndrome is an inherited condition often manifesting with seizures, ataxia, developmental delay, and dysarthria. The disorder is rare, appearing in approximately 1 in 40,000 live births. Consequently, providing these patients with a suitable plan by which to administer anesthetics remains problematic.
  
  
  METHODS
  We report a male patient with Leigh's syndrome and a family history suggestive of unknown hypotonia and malignant hyperthermia presenting for dental rehabilitation.
  
  
  CONCLUSIONS
  Dexmedetomidine with remifentanil can be used with no complication in this senerio.
authors.affiliation: Division of Pediatric Anesthesia, Arkansas Children's Hospital, Arkansas, USA.
authors.forename: M-Irfan
authors.initials: MI
authors.lastname: Suleman
authors.affiliation: Department of Anesthesiology, University of Arkansas for Medical Sciences, Arkansas, USA.
authors.forename: Thejovathi
authors.initials: T
authors.lastname: Edala
authors.affiliation: Division of Pediatric Anesthesia, Arkansas Children's Hospital, Arkansas, USA.
authors.forename: Edwin
authors.initials: E
authors.lastname: Abraham
authors.affiliation: Division of Pediatric Anesthesia, Arkansas Children's Hospital, Arkansas, USA.
authors.forename: M-Saif
authors.initials: MS
authors.lastname: Siddiqu
keywords: Anesthesia; Encephalomyelopathy; Leigh’s Syndrome; Malignant Hyperthermia; Mitochondrial Disorders