title: [Clinical management of rotator cuff tears. Current concepts in cell-based therapy strategies].
abstract: Due to the increasing demand for functionality in an aging yet physically active society, the treatment of rotator cuff tears is of ever-growing importance. Despite intensive research efforts, the treatment of degenerative rotator cuff tears, in particular their long-term outcome, is still a challenge. While in recent years the focus was on biomechanics and the technical aspects of rotator cuff reconstruction, attention has now turned to the biological considerations of tendon regeneration. This article highlights the current state of biological rotator cuff augmentation in a clinical setting and provides an insight into and an outlook on the experimental procedures.
authors.affiliation: Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation, LMU München - Campus Großhadern, Marchioninistraße 15, 81377, München, Deutschland. andreas.ficklscherer@med.uni-muenchen.de.
authors.forename: A
authors.initials: A
authors.lastname: Ficklscherer
authors.affiliation: Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation, LMU München - Campus Großhadern, Marchioninistraße 15, 81377, München, Deutschland.
authors.forename: M F
authors.initials: MF
authors.lastname: Pietschmann
authors.affiliation: Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation, LMU München - Campus Großhadern, Marchioninistraße 15, 81377, München, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Bendiks
authors.affiliation: Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation, LMU München - Campus Großhadern, Marchioninistraße 15, 81377, München, Deutschland.
authors.forename: B P
authors.initials: BP
authors.lastname: Roßbach
authors.affiliation: Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation, LMU München - Campus Großhadern, Marchioninistraße 15, 81377, München, Deutschland.
authors.forename: P E
authors.initials: PE
authors.lastname: Müller
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D000070636:Rotator Cuff Injuries / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000379:methods*; D016896:Treatment Outcome
keywords: Growth factors; Platelet-rich plasma; Reconstructive Surgical Procedure; Rotator cuff; Stem cells