title: Third molar development by measurements of open apices in an Italian sample of living subjects.
abstract: The aim of this study is to analyse the age-predicting performance of third molar index (I3M) in dental age estimation. A multiple regression analysis was developed with chronological age as the independent variable. In order to investigate the relationship between the I3M and chronological age, the standard deviation and relative error were examined. Digitalized orthopantomographs (OPTs) of 975 Italian healthy subjects (531 female and 444 male), aged between 9 and 22 years, were studied. Third molar development was determined according to Cameriere et al. (2008). Analysis of covariance (ANCOVA) was applied to study the interaction between I3M and the gender. The difference between age and third molar index (I3M) was tested with Pearson's correlation coefficient. The I3M, the age and the gender of the subjects were used as predictive variable for age estimation. The small F-value for the gender (F = 0.042, p = 0.837) reveals that this factor does not affect the growth of the third molar. Adjusted R(2) (AdjR(2)) was used as parameter to define the best fitting function. All the regression models (linear, exponential, and polynomial) showed a similar AdjR(2). The polynomial (2nd order) fitting explains about the 78% of the total variance and do not add any relevant clinical information to the age estimation process from the third molar. The standard deviation and relative error increase with the age. The I3M has its minimum in the younger group of studied individuals and its maximum in the oldest ones, indicating that its precision and reliability decrease with the age.
authors.affiliation: Departamento de Antropologia, Facultad de Ciencias Sociales y Jurídicas, Universidad de Tarapacá, Arica, Chile; AgEstimation Project, Institute of Legal Medicine, University of Macerata, Macerata, Italy. Electronic address: sluca@ugr.es.
authors.forename: Stefano
authors.initials: S
authors.lastname: De Luca
authors.affiliation: AgEstimation Project, Institute of Legal Medicine, University of Macerata, Macerata, Italy; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Pacifici
authors.affiliation: AgEstimation Project, Institute of Legal Medicine, University of Macerata, Macerata, Italy; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy.
authors.forename: Luciano
authors.initials: L
authors.lastname: Pacifici
authors.affiliation: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Polimeni
authors.affiliation: Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy.
authors.forename: Sara Giulia
authors.initials: SG
authors.lastname: Fischetto
authors.affiliation: AgEstimation Project, Institute of Legal Medicine, University of Macerata, Macerata, Italy.
authors.forename: Luz Andrea
authors.initials: LA
authors.lastname: Velandia Palacio
authors.affiliation: School of Applied Science, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
authors.forename: Stefano
authors.initials: S
authors.lastname: Vanin
authors.affiliation: AgEstimation Project, Institute of Legal Medicine, University of Macerata, Macerata, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Cameriere
mesh_terms: D000293:Adolescent; D000366:Age Determination by Teeth / Q000379:methods*; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008964:Molar, Third / Q000000981:diagnostic imaging / Q000254:growth & development*; D019252:Radiography, Dental, Digital; D011862:Radiography, Panoramic; D012044:Regression Analysis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D019227:Tooth Apex / Q000000981:diagnostic imaging / Q000254:growth & development*; D055815:Young Adult
keywords: Age estimation; Dental development; Forensic sciences; Italy; Third molar index