title: Gastrointestinal disease in Sjogren's syndrome: related to food hypersensitivities.
abstract: Patients with Sjogren's syndrome (SS) frequently have irritable bowel like symptoms (IBS). Some have celiac sprue. The current studies were designed to examine the presence of food hypersensitivities in a population of patients with SS and IBS. Ten patients were selected from the autoimmune disease clinics at SUNY at Buffalo who had SS and IBS symptoms. Food hypersensitivities were determined by specific IgG ImmunoCAP(®) assays. Symptoms of abdominal pain, bloating, diarrhea and joint pain were eliminated with dietary restriction of foods to which hypersensitivity was demonstrated. Symptoms recurred with re-institution of offending foods. Resolution of fatigue required elimination of offending foods as well as treatment of underlying metabolic disorders. The presence of IBS in patients with SS should lead to investigation of food hypersensitivities as possible culprits.
authors.affiliation: Department of Medicine, SUNY at Buffalo School of Medicine, Buffalo, 14203 NY USA.
authors.forename: Christine
authors.initials: C
authors.lastname: Kim-Lee
authors.affiliation: Department of Oral Diagnostic Sciences, SUNY at Buffalo School of Dental Medicine, Buffalo, 14214 NY USA ; Immco Diagnostics, 640 Ellicott Street, Buffalo, 14203 NY USA.
authors.forename: Lakshmanan
authors.initials: L
authors.lastname: Suresh
authors.affiliation: Department of Medicine, SUNY at Buffalo School of Medicine, Buffalo, 14203 NY USA.
authors.forename: Julian L
authors.identifier: 0000-0003-4505-796X
authors.initials: JL
authors.lastname: Ambrus