title: Genome editing: A breakthrough in life science and medicine.
abstract: Genome editing technologies represent a major breakthrough that has dramatically altered strategies in a wide range of biological studies. Genome editing simplifies and accelerates the creation of animal disease models and enables construction of models in most animal species, even those that are not amenable to conventional gene targeting technology.
authors.affiliation: Laboratory of Genome Science, Biosignal Genome Resource Center, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi 371-8512, Japan.
authors.forename: Izuho
authors.initials: I
authors.lastname: Hatada
authors.forename: Takuro
authors.initials: T
authors.lastname: Horii
mesh_terms: D000818:Animals; D001690:Biological Science Disciplines / Q000639:trends*; D064112:Clustered Regularly Interspaced Short Palindromic Repeats / Q000502:physiology; D004195:Disease Models, Animal; D000072669:Gene Editing / Q000266:history / Q000379:methods / Q000639:trends*; D018390:Gene Targeting / Q000379:methods; D015316:Genetic Therapy / Q000266:history / Q000379:methods / Q000639:trends; D049674:History, 21st Century; D006801:Humans; D008511:Medicine / Q000639:trends*