title: Two cases of immune thrombocytopenia associated with pembrolizumab.
authors.affiliation: APHP, service de médecine interne et immunologie, Hôpital Bicêtre, F-94270 Le Kremlin Bicêtre, France; Ecole du Val de Grâce, F-75230 Paris Cedex 05, France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Le Roy
authors.affiliation: APHP, Medical Oncology Department, Henri-Mondor Hospital, F-94000 Créteil, France.
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Kempf
authors.affiliation: APHP, service de médecine interne et immunologie, Hôpital Bicêtre, F-94270 Le Kremlin Bicêtre, France.
authors.forename: Felix
authors.initials: F
authors.lastname: Ackermann
authors.affiliation: Medical Oncology Department, Gustave Roussy Cancer Campus, F-94805 Villejuif, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Routier
authors.affiliation: Medical Oncology Department, Gustave Roussy Cancer Campus, F-94805 Villejuif, France; University of Paris-Sud, F-94043 Kremlin-Bicêtre, France.
authors.forename: Caroline
authors.initials: C
authors.lastname: Robert
authors.affiliation: Drug Development Department, Gustave Roussy Cancer Campus, F-94805 Villejuif, France.
authors.forename: Anthony
authors.initials: A
authors.lastname: Turpin
authors.affiliation: Drug Development Department, Gustave Roussy Cancer Campus, F-94805 Villejuif, France.
authors.forename: Aurélien
authors.initials: A
authors.lastname: Marabelle
authors.affiliation: Medical Oncology Department, Gustave Roussy Cancer Campus, F-94805 Villejuif, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Mateus
authors.affiliation: APHP, service de médecine interne et immunologie, Hôpital Bicêtre, F-94270 Le Kremlin Bicêtre, France; Drug Development Department, Gustave Roussy Cancer Campus, F-94805 Villejuif, France.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Michot
authors.affiliation: APHP, service de médecine interne et immunologie, Hôpital Bicêtre, F-94270 Le Kremlin Bicêtre, France; University of Paris-Sud, F-94043 Kremlin-Bicêtre, France. Electronic address: olivier.lambotte@aphp.fr.
authors.forename: Olivier
authors.initials: O
authors.lastname: Lambotte
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D014408:Biomarkers, Tumor / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics / Q000556:secondary; D008875:Middle Aged; D009154:Mutation; D010976:Platelet Count; D047428:Protein Kinase Inhibitors / Q000009:adverse effects*; D048493:Proto-Oncogene Proteins B-raf / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D012074:Remission Induction; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D047428:Protein Kinase Inhibitors; C582435:pembrolizumab; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf