title: Mycobacterium genavense infection in a solid organ recipient: a diagnostic and therapeutic challenge.
abstract: Renal transplant recipients are highly susceptible to infections caused by uncommon pathogens because of their immunocompromised state. We report a case of disseminated Mycobacterium genavense infection in a patient with a combined renal and cardiac transplant. Diagnosing M. genavense infections remains a challenge because of the absence of specific clinical symptoms in combination with the difficulties of culturing the organism using standard mycobacterial culture procedures. This clinical case demonstrates the importance of molecular techniques as part of the initial work-up in order to rapidly establish the diagnosis.
authors.affiliation: Department of Nephrology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: S
authors.initials: S
authors.lastname: Ombelet
authors.affiliation: Department of General Internal Medicine, University Hospitals Leuven, Leuven, Belgium.
authors.forename: E
authors.initials: E
authors.lastname: Van Wijngaerden
authors.affiliation: Department of Laboratory Medicine, University Hospitals Leuven, Leuven, Belgium.
authors.forename: K
authors.initials: K
authors.lastname: Lagrou
authors.affiliation: Department of Pathology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: T
authors.initials: T
authors.lastname: Tousseyn
authors.affiliation: Department of Nuclear Medicine, University Hospitals Leuven, Leuven, Belgium.
authors.forename: O
authors.initials: O
authors.lastname: Gheysens
authors.affiliation: Department of Cardiology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: W
authors.initials: W
authors.lastname: Droogne
authors.affiliation: Department of Nephrology, AZ Groeninge, Kortrijk, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Doubel
authors.affiliation: Department of Nephrology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: D
authors.initials: D
authors.lastname: Kuypers
authors.affiliation: Department of Nephrology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: K J
authors.initials: KJ
authors.lastname: Claes
mesh_terms: D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology; D009170:Nontuberculous Mycobacteria / Q000235:genetics / Q000302:isolation & purification*
keywords: Mycobacterium genavense; outcome; renal transplantation