title: Cutaneous infectious diseases: Kids are not just little people.
abstract: The changes in immune response that occur with age play a significant role in disease presentation and patient management. Evolution of the innate and adaptive immune systems throughout life, influenced partly by hormonal changes associated with puberty, plays a role in the differences between pediatric and adult response to disease. We review a series of manifestations of dermatologic infectious diseases spanning bacterial, viral, and fungal origins that can be seen in both pediatric and adult age groups and highlight similarities and differences in presentation and disease course. Therapeutic options are also discussed for these infectious diseases, with particular attention to variations in management between these population subgroups, given differences in pharmacokinetics and side effect profiles.
authors.affiliation: Department of Pediatric Dermatology, University of California at San Diego School of Medicine, San Diego, CA.
authors.forename: Shehla
authors.initials: S
authors.lastname: Admani
authors.affiliation: Department of Dermatology, University of Connecticut Health Sciences, 21 South Road, Farmington, CT, 06032.
authors.forename: Sphoorthi
authors.initials: S
authors.lastname: Jinna
authors.affiliation: Fellowship Training Program, Rady Children's Hospital, Department of Clinical Pediatrics & Medicine, University of California at San Diego School of Medicine, 8010 Frost Street, Suite 602, San Diego, CA 92123.
authors.forename: Sheila Fallon
authors.initials: SF
authors.lastname: Friedlander
authors.affiliation: Department of Dermatology, University of Connecticut Health Sciences, 21 South Road, Farmington, CT, 06032. Electronic address: sloan@uchc.edu.
authors.forename: Brett
authors.initials: B
authors.lastname: Sloan
mesh_terms: D000169:Acrodermatitis / Q000453:epidemiology / Q000821:virology; D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000188:drug therapy; D016731:Erythema Infectiosum / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008193:Lyme Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D055624:Methicillin-Resistant Staphylococcus aureus; D008976:Molluscum Contagiosum / Q000150:complications / Q000188:drug therapy; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis / Q000188:drug therapy; D012874:Skin Diseases, Infectious / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D013207:Staphylococcal Skin Infections / Q000188:drug therapy / Q000382:microbiology; D014006:Tinea Capitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents