title: Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada.
abstract: Antimicrobial resistance profiles were determined for Neisseria gonorrhoeae strains isolated in Canada during 2010-2014. The proportion of isolates with decreased susceptibility to cephalosporins declined significantly between 2011 and 2014, whereas azithromycin resistance increased significantly during that period. Continued surveillance of antimicrobial drug susceptibilities is imperative to inform treatment guidelines.
authors.forename: I
authors.initials: I
authors.lastname: Martin
authors.forename: P
authors.initials: P
authors.lastname: Sawatzky
authors.forename: G
authors.initials: G
authors.lastname: Liu
authors.forename: V
authors.initials: V
authors.lastname: Allen
authors.forename: B
authors.initials: B
authors.lastname: Lefebvre
authors.forename: L
authors.initials: L
authors.lastname: Hoang
authors.forename: S
authors.initials: S
authors.lastname: Drews
authors.forename: G
authors.initials: G
authors.lastname: Horsman
authors.forename: J
authors.initials: J
authors.lastname: Wylie
authors.forename: D
authors.initials: D
authors.lastname: Haldane
authors.forename: R
authors.initials: R
authors.lastname: Garceau
authors.forename: S
authors.initials: S
authors.lastname: Ratnam
authors.forename: T
authors.initials: T
authors.lastname: Wong
authors.forename: C
authors.initials: C
authors.lastname: Archibald
authors.forename: M R
authors.initials: MR
authors.lastname: Mulvey
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use*; D002170:Canada; D002511:Cephalosporins / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial / Q000187:drug effects*; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D009344:Neisseria gonorrhoeae / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D017963:Azithromycin
keywords: Canada; Neisseria gonorrhoeae; antimicrobial resistance; azithromycin; bacteria; cephalosporins; gonorrhea; gonorrhoea; rates; susceptibility