title: Safety Assessment of Boron Nitride as Used in Cosmetics.
abstract: The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of boron nitride which functions in cosmetics as a slip modifier (ie, it has a lubricating effect). Boron nitride is an inorganic compound with a crystalline form that can be hexagonal, spherical, or cubic; the hexagonal form is presumed to be used in cosmetics. The highest reported concentration of use of boron nitride is 25% in eye shadow formulations. Although boron nitride nanotubes are produced, boron nitride is not listed as a nanomaterial used in cosmetic formulations. The Panel reviewed available chemistry, animal data, and clinical data and concluded that this ingredient is safe in the present practices of use and concentration in cosmetic formulations.
authors.affiliation: Cosmetic Ingredient Review Senior Scientific Analyst/Writer, Washington, DC, USA.
authors.forename: Monice M
authors.initials: MM
authors.lastname: Fiume
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: Wilma F
authors.initials: WF
authors.lastname: Bergfeld
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: Donald V
authors.initials: DV
authors.lastname: Belsito
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: Ronald A
authors.initials: RA
authors.lastname: Hill
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: Curtis D
authors.initials: CD
authors.lastname: Klaassen
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Liebler
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: James G
authors.initials: JG
authors.lastname: Marks
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: Ronald C
authors.initials: RC
authors.lastname: Shank
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Slaga
authors.affiliation: Cosmetic Ingredient Review Expert Panel Member, Washington, DC, USA.
authors.forename: Paul W
authors.initials: PW
authors.lastname: Snyder
authors.affiliation: Former Director, Cosmetic Ingredient Review, Washington, DC, USA.
authors.forename: F Alan
authors.initials: FA
authors.lastname: Andersen
mesh_terms: D000818:Animals; D001896:Boron Compounds / Q000737:chemistry / Q000493:pharmacokinetics / Q000633:toxicity*; D055598:Chemical Phenomena; D003257:Consumer Product Safety; D003358:Cosmetics / Q000737:chemistry / Q000493:pharmacokinetics / Q000633:toxicity*; D004249:DNA Damage / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D043942:Nanotubes / Q000737:chemistry / Q000633:toxicity; D018570:Risk Assessment; D012867:Skin / Q000187:drug effects / Q000378:metabolism; D018675:Toxicity Tests
chemical_list: D001896:Boron Compounds; D003358:Cosmetics; C017282:boron nitride
keywords: boron nitride; cosmetics; safety