title: Outcome of cataract surgery following simple limbal epithelial transplantation for lime injury-induced limbal stem cell deficiency.
abstract: A 19-year-old woman presented to us after being diagnosed elsewhere with right eye total limbal stem cell deficiency resulting from a lime burn. She was advised to undergo limbal stem cell transplantation, but failed to immediately do so. Two years later, she underwent cultivated limbal epithelial transplantation (CLET). As she had severe loss of vision with persisting conjunctival nodule and symblepharon 2 years following surgery, an impression of failed CLET was formed. Subsequently, simple limbal epithelial transplantation (SLET) was performed. Nine months later, she developed a cataract in her right eye; the cataract was extracted and posterior chamber intraocular lens implanted. The unaided visual acuity improved from light perception at presentation to 20/60 at 1-week postoperatively. At 5 months follow-up, the patient continued to maintain 20/60 visual acuity in her right eye. This case describes the outcome of cataract surgery following SLET, emphasising the need to perform cataract surgery in complicated cataracts for a better visual prognosis.
authors.affiliation: Cornea and Anterior Segment Services, L V Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Dhanyasree
authors.initials: D
authors.lastname: Nair
authors.affiliation: Prof Brien Holden Eye Research Centre, L V Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Ashik
authors.identifier: http://orcid.org/0000-0001-5520-4930
authors.initials: A
authors.lastname: Mohamed
authors.affiliation: Cornea and Anterior Segment Services, L V Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Virender S
authors.identifier: http://orcid.org/0000-0002-8229-4158
authors.initials: VS
authors.lastname: Sangwan
mesh_terms: D000328:Adult; D002057:Burns, Chemical / Q000150:complications / Q000601:surgery*; D017610:Calcium Compounds; D002386:Cataract / Q000628:therapy*; D002387:Cataract Extraction; D003316:Corneal Diseases / Q000209:etiology / Q000601:surgery*; D016039:Corneal Transplantation; D019573:Epithelium, Corneal / Q000166:cytology*; D005126:Eye Burns / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D016850:Limbus Corneae / Q000166:cytology*; D010087:Oxides; D033581:Stem Cell Transplantation; D013234:Stem Cells; D015354:Vision, Low; D055815:Young Adult
chemical_list: D017610:Calcium Compounds; D010087:Oxides; C016538:lime