title: Does the fat-but-fit paradigm hold true for all-cause mortality when considering the duration of overweight/obesity? Analyzing the WATCH (Weight, Activity and Time Contributes to Health) paradigm.
abstract: BACKGROUND
  Physical activity has been shown to attenuate the association between overweight/obesity and mortality. Much less is known, however, on how the duration of overweight/obesity potentially alters this association, which was the purpose of this study.
  
  
  METHODS
  The 1999-2006 NHANES was used and 11,057 adults (ages 36-85) were evaluated. Eight mutually exclusive groups were created: (1) physically active, normal weight now and 10years ago; (2) physically inactive, normal weight now and 10years ago; (3) physically active, overweight/obese now but normal weight 10years ago; (4) physically inactive, normal weight now but overweight/obese 10years ago; (5) physically active, overweight/obese now but normal weight 10years ago; (6) physically inactive, overweight/obese now but normal weight 10years ago; (7) physically active, overweight/obese now and 10years ago; and (8) physically inactive, overweight/obese now and 10years ago.
  
  
  RESULTS
  After adjustments, only those individuals that were inactive were at a significantly increased risk for all-cause mortality independent of overweight/obesity status (Groups 2, 4, 6, 8).
  
  
  CONCLUSIONS
  In alignment with the Exercise is Medicine initiative®, our results provide support for clinicians to perform routine assessments of physical activity, and to further promote physical activity among all individuals regardless of body mass status.
authors.affiliation: Department of Health, Exercise Science, and Recreation Management, Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, United States.
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Dankel
authors.affiliation: Department of Health, Exercise Science, and Recreation Management, Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, United States.
authors.forename: Jeremy P
authors.initials: JP
authors.lastname: Loenneke
authors.affiliation: Department of Health, Exercise Science and Recreation Management, Center for Health Behavior Research, The University of Mississippi, University, MS, United States. Electronic address: pdloprin@olemiss.edu.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Loprinzi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001835:Body Weight; D002423:Cause of Death; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D009765:Obesity / Q000401:mortality; D050177:Overweight / Q000401:mortality*; D010809:Physical Fitness; D012307:Risk Factors
keywords: Epidemiology; Fat paradigm; Obesity duration