title: Electrochemical preparation of nickel and copper oxides-decorated graphene composite for simultaneous determination of dopamine, acetaminophen and tryptophan.
abstract: In the present work, transition metal oxides decorated graphene (GR) have been fabricated for simultaneous determination of dopamine (DA), acetaminophen (AC) and tryptophan (Trp) using square wave voltammetry. Electro-deposition is a facile preparation strategy for the synthesis of nickel oxide (NiO) and copper oxide (CuO) nanoparticles. GR can be modified by using citric acid to produce more functional groups, which is conducive to the deposition of dispersed metal particles. The morphologies and interface properties of the obtained NiO-CuO/GR nanocomposite were examined by scanning electron microscopy, energy dispersive X-ray spectroscopy and Raman spectroscopy. Moreover, the electrochemical performances of the composite film were investigated by cyclic voltammetry and electrochemical impedance spectroscopy. The modified electrode exhibited that the linear response ranges for detecting DA, AC and Trp were 0.5-20 μM, 4-400 μM and 0.3-40 μM, respectively, and the detection limits were 0.17 μM, 1.33 μM and 0.1 μM (S/N=3). Under optimal conditions, the sensor displayed high sensitivity, excellent stability and satisfactory results in real samples analysis.
authors.affiliation: Department of Chemistry, Shanghai University, Shanghai 200444, PR China.
authors.forename: Bingdi
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Chemistry, Shanghai University, Shanghai 200444, PR China.
authors.forename: Xiaoqian
authors.initials: X
authors.lastname: Ouyang
authors.affiliation: Department of Chemistry, Shanghai University, Shanghai 200444, PR China. Electronic address: wdingyp@sina.com.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Department of Chemistry, Shanghai University, Shanghai 200444, PR China.
authors.forename: Liqing
authors.initials: L
authors.lastname: Luo
authors.affiliation: Department of Chemistry, Shanghai University, Shanghai 200444, PR China.
authors.forename: Duo
authors.initials: D
authors.lastname: Xu
authors.affiliation: Department of Chemistry, Shanghai University, Shanghai 200444, PR China.
authors.forename: Yanqun
authors.initials: Y
authors.lastname: Ning
mesh_terms: D000082:Acetaminophen / Q000032:analysis*; D003300:Copper / Q000737:chemistry*; D004298:Dopamine / Q000032:analysis*; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D005898:Glass / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D009532:Nickel / Q000737:chemistry*; D015203:Reproducibility of Results; D013997:Time Factors; D014364:Tryptophan / Q000032:analysis*
chemical_list: D000082:Acetaminophen; D006108:Graphite; D003300:Copper; D009532:Nickel; D014364:Tryptophan; C028007:nickel monoxide; C000520:cuprous oxide; D004298:Dopamine
keywords: Acetaminophen; Dopamine; Electro-deposition; Graphene; Transition metal oxides; Tryptophan