title: [Roles of Inflammatory Reaction and Cytokines in Chronic Postsurgical Pain].
abstract: Chronic postsurgical pain (CPSP) is characterized by high incidence,prolonged duration,multiple risk factors,and complicated pathogenesis. It seriously impairs patients' quality of life,especially after thoracotomy. Perioperative nerve injury is a major cause of CPSP. Meanwhile,the excessive neuroinflammation and inflammatory cytokines caused by surgery also accelerate the formation of CPSP. This review aims to provide an overview of the recent advances in the roles of inflammatory reaction and cytokines in the development of CPSP.
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Ling
authors.initials: L
authors.lastname: Lan
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Le
authors.initials: L
authors.lastname: Shen
authors.affiliation: Department of Anesthesiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
authors.forename: Yu-guang
authors.initials: YG
authors.lastname: Huang
mesh_terms: D059350:Chronic Pain; D016207:Cytokines; D006801:Humans; D015994:Incidence; D007249:Inflammation; D010149:Postoperative Pain; D011788:Quality of Life; D012307:Risk Factors
chemical_list: D016207:Cytokines