title: [SPLEEN ORGAN-PRESERVING SURGERIES - ORGAN HISTO- ULTRASTRUCTURE].
abstract: The aim of our work is to study the functional activity of the spleen according to the histological and ultrastructural features of the organ as an indicator of the functional viability. Experiments performed using 36 white male rats (body mass 130-160 g.). 40-60% of the rat splenic tissue was removed by laparotomy under ether anesthesia. The rats were euthanized under general anesthesia after 1, 7, 15, 30, 90 and 180 days after surgery. Histological sections stained with hematoxylin and eosin. Ultrathin sections were studied by the electron microscope TESLA BS 500 with 4000 to 14000 magnification. It is shown that the significant changes in the spleen after organ - preserving surgery are the microcirculatiry disturbance in the first day of the experiment with the ewerblow cells to the bloodstream, a phenomenon of adhesion, which blocked blood circulation. The thickness of the capsule and the weight of the spleen do not reach the initiae values, but histo- and ultrastructural data suggest developins of defense function of the spleen and expediency of organ-preserving surgery.
authors.affiliation: I. Javakhishvili Tbilisi State University, A. Natishvili Institute of Morphology, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Amiranidze
authors.affiliation: I. Javakhishvili Tbilisi State University, A. Natishvili Institute of Morphology, Georgia.
authors.forename: Ts
authors.initials: Ts
authors.lastname: Sumbadze
authors.affiliation: I. Javakhishvili Tbilisi State University, A. Natishvili Institute of Morphology, Georgia.
authors.forename: I
authors.initials: I
authors.lastname: Sikharulidze
authors.affiliation: I. Javakhishvili Tbilisi State University, A. Natishvili Institute of Morphology, Georgia.
authors.forename: S
authors.initials: S
authors.lastname: Gvidani
authors.affiliation: I. Javakhishvili Tbilisi State University, A. Natishvili Institute of Morphology, Georgia.
authors.forename: S
authors.initials: S
authors.lastname: Markaryan
mesh_terms: D000818:Animals; D004801:Eosine Yellowish-(YS); D006416:Hematoxylin; D006651:Histocytochemistry; D008297:Male; D008867:Microtomy; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D009929:Organ Size; D051381:Rats; D013154:Spleen / Q000098:blood supply / Q000601:surgery / Q000648:ultrastructure*; D013156:Splenectomy / Q000379:methods*
chemical_list: D004801:Eosine Yellowish-(YS); D006416:Hematoxylin