title: Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic.
abstract: A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses.
authors.affiliation: Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, University of Belgrade Belgrade, Serbia.
authors.forename: Veljko
authors.initials: V
authors.lastname: Veljkovic
authors.affiliation: Galveston National Laboratory, Department of Pathology, University of Texas Medical Branch Galveston, TX, USA.
authors.forename: Slobodan
authors.initials: S
authors.lastname: Paessler
authors.affiliation: Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, University of Belgrade Belgrade, Serbia.
authors.forename: Sanja
authors.initials: S
authors.lastname: Glisic
authors.affiliation: Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, University of Belgrade Belgrade, Serbia.
authors.forename: Jelena
authors.initials: J
authors.lastname: Prljic
authors.affiliation: Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, University of Belgrade Belgrade, Serbia.
authors.forename: Vladimir R
authors.initials: VR
authors.lastname: Perovic
authors.affiliation: Center for Multidisciplinary Research, Institute of Nuclear Sciences Vinca, University of Belgrade Belgrade, Serbia.
authors.forename: Nevena
authors.initials: N
authors.lastname: Veljkovic
authors.affiliation: Department of Biomedical Informatics, Arizona State UniversityScottsdale, AZ, USA; Center for Environmental Security, Biodesign Institute and Global Security Initiative, Arizona State UniversityTempe, AZ, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Scotch
keywords: H3N2; influenza virus; pandemic potential; phylogenetic analysis; seasonal influenza vaccine effectiveness