title: [Semi-quantitative study of structural abnormalities and changes of oxygenation function using CT in patients with post primary tuberculosis].
abstract: OBJECTIVE
  To investigate the relationship between structural abnormalities with semi-quantitative score of CT and changes of oxygenation function in patients with post primary tuberculosis.
  
  
  METHODS
  110 in-patients with post primary tuberculosis in Haihe clinical college of Tianjin medical university from January 2014 to August 2014 were enrolled in this study, all patients underwent CT and blood gas analysis. All lesions in lung as a whole and different CT signs of lesions were evaluated by retrospective semi-quantitative score respectively, total scores obtained by adding the scores of different lesions. The correlation between these scores and the results of blood gas analysis were evaluated. CT scores were compared between group 1 (PaO2/FiO2<300 mmHg) and group 2 (PaO2/FiO2≥300 mmHg) of patients.
  
  
  RESULTS
  Overall score of lung lesions and total scores which obtained by adding the score of different signs in patients showed correlation with PaO2/FiO2, and the method of overall score of lung lesions was easy to do. Scores of nodules and tree-in-bud pattern, consolidation, bronchial lesions, cavity showed correlation between PaO2/FiO2. There was no correlation between score of ground-glass opacity and PaO2/FiO2. Nodules and tree-in-bud pattern were more common in post primary tuberculosis, 87.3% (96/110) and 70% (77/110) respectively. Lobular consolidation was dominant in consolidation of patients, 83.6% (92/110). Bronchial wall thickening and bronchiectasis had higher incidence in larger airways, 87.3% (96/110) and 75.5% (83/110) respectively. Cavities were given priority to with thin walled, 53.6% (59/110). Overall score of lung lesions and scores of bronchial lesions, consolidation, cavity in groups 1 were significantly higher than group 2.
  
  
  CONCLUSIONS
  Semi-quantitative score of CT can better quantify structural abnormalities of the lung, sensitively reflect changes of oxygenation, and bronchial lesions play an important role in the process of post primary tuberculosis.
authors.affiliation: Department of Radiology, Haihe Clinical College of Tianjin Medical University, Tianjin 300350, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Yu
authors.affiliation: Email: wq572004@163.com.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wu
authors.forename: Tielian
authors.initials: T
authors.lastname: Yu
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Li
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
mesh_terms: D001784:Blood Gas Analysis; D001987:Bronchiectasis; D006801:Humans; D008168:Lung; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary