title: Protecting effect of gabapentin for nausea and vomiting in the surgery of cesarean after spinal anesthesia.
abstract: BACKGROUND
  Nausea and vomiting are the most common effects after cesarean delivery with spinal anesthesia that was associated with problems such as pneumonia, delay in patient discharge, electrolyte abnormalities, and the maternal dissatisfaction.
  
  
  OBJECTIVE
  The aim of this study was to evaluate the effects of gabapentin in preventing nausea and vomiting after spinal anesthesia in cesarean delivery.
  
  
  METHODS
  This study as a double-blind clinical trial was done on 200 candidates of cesarean with a random distribution. Patients without cardiovascular diseases and in 1 and 2 American Society of Anesthesiologists were divided into two groups. Treatment group received 600 mg capsule (gabapentin) 1 h before surgery and the control group received placebo. The severity of nausea and vomiting were evaluated according to 4 Scores every hour to 4 h after the withdrawal of mother from the recovery section.
  
  
  RESULTS
  In this study, there is no significant difference in demographic information between these two groups. In the 1(st) h, there is a significant difference between the severity of nausea and vomiting in these two groups, but there is not a significant difference between 2 and 4 h after surgery. However, the incidence of nausea between the two groups shows a significant correlation.
  
  
  CONCLUSIONS
  A single dose of gabapentin 1 h before cesarean delivery decreases the incidence of nausea and vomiting after surgery.
authors.affiliation: Department of Anesthesiology, Arak University of Medical Sciences, Arak, Iran.
authors.forename: Fereshteh
authors.initials: F
authors.lastname: Memari
authors.affiliation: Department of Education of Development Center, Arak University of Medical Sciences, Arak, Iran.
authors.forename: Rahmatollah
authors.initials: R
authors.lastname: Jadidi
authors.affiliation: Department of Anesthesiology, Arak University of Medical Sciences, Arak, Iran.
authors.forename: Afsaneh
authors.initials: A
authors.lastname: Noroozi
authors.affiliation: Neurology and Neuroscience Research Center, Department of Epidemiology and Biostatistics, School of Health, Qom University of Medical Sciences, Qom, Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Mohammadbeigi
authors.affiliation: Department of Ophthalmology, Arak University of Medical Sciences, Arak, Iran.
authors.forename: Jamal
authors.initials: J
authors.lastname: Falahati
keywords: Cesarean; gabapentin; nausea; spinal anesthesia; vomiting