title: Rehabilitation following cerebral anoxia: An assessment of 27 patients.
abstract: OBJECTIVE
  (1) To evaluate cognitive and emotional impairments, disability and quality-of-life for adults with cerebral anoxia institutionalized in residential care facilities. (2) To evaluate the efficacy of medication, psychotherapy, support group and therapeutic activities.
  
  
  METHODS
  Twenty-seven persons with cerebral anoxia were recruited, on average 8 years post-injury. Only 20 went through the whole study. Over three consecutive 2-month periods, they were assessed four times to evaluate: baseline observations (T1-T2), adjustment of their medication (T2-T3); and the effect of psychotherapy, support group and therapeutic activities such as physical and artistic or cultural activities usually proposed in the facilities involved (T3-T4). Examined variables at all time points were cognitive status, anxiety and depression, anosognosia, alexithymia, disability and quality-of-life.
  
  
  RESULTS
  All participants exhibited cognitive and emotional impairments comparable to those reported in the literature. Statistical analyses revealed good baseline stability of their condition and no significant effects of changes in medication (between T2 and T3). Conversely, following implementation of psychotherapy, support group and therapeutic activities (between T3 and T4), quality-of-life and social participation were significantly improved.
  
  
  CONCLUSIONS
  Social participation and quality-of-life for persons instutionalized several years after cerebral anoxia were improved by psychotherapeutic and therapeutic activities.
authors.affiliation: a Laboratory of Psychopathology and Neuropsychology , University of Paris 8 , Saint-Denis , France .|b Laboratory 'Paragraphe' , University Paris 8 , Saint-Denis , France .
authors.forename: Eva
authors.initials: E
authors.lastname: Tazopoulou
authors.affiliation: c Facilities for Persons with Acquired Brain Injury , Ivry sur Seine Cedex , France .
authors.forename: Raphaële
authors.initials: R
authors.lastname: Miljkovitch
authors.affiliation: b Laboratory 'Paragraphe' , University Paris 8 , Saint-Denis , France .|d Department of Neurorehabilitation , University Hospital , Garches , France .
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Truelle
authors.affiliation: b Laboratory 'Paragraphe' , University Paris 8 , Saint-Denis , France .|d Department of Neurorehabilitation , University Hospital , Garches , France .
authors.forename: Alexis
authors.initials: A
authors.lastname: Schnitzler
authors.affiliation: b Laboratory 'Paragraphe' , University Paris 8 , Saint-Denis , France .|e French National Union for Families of Persons with Acquired Brain Injuries , Paris , France , and.
authors.forename: Michel
authors.initials: M
authors.lastname: Onillon
authors.affiliation: b Laboratory 'Paragraphe' , University Paris 8 , Saint-Denis , France .
authors.forename: Thierry
authors.initials: T
authors.lastname: Zucco
authors.affiliation: f Department of Psychiatry , University of Melbourne , Melbourne , Australia.
authors.forename: Graeme
authors.initials: G
authors.lastname: Hawthorne
authors.affiliation: a Laboratory of Psychopathology and Neuropsychology , University of Paris 8 , Saint-Denis , France .
authors.forename: Michèle
authors.initials: M
authors.lastname: Montreuil
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000209:etiology / Q000523:psychology; D015928:Cognitive Behavioral Therapy; D004185:Disability Evaluation; D006233:Persons with Disabilities; D004644:Emotions / Q000502:physiology; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000175:diagnosis / Q000523:psychology / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D011613:Psychotherapy; D011788:Quality of Life; D012189:Retrospective Studies
keywords: Anoxia; disability; psychotherapy; quality-of-life; rehabilitation; social re-integration