title: Pyogenic lumbar spondylodiscitis treated with transforaminal lumbar interbody fusion: safety and outcomes.
abstract: Our aim was to study the safety and outcomes of posterior instrumentation and transforaminal lumbar interbody fusion (TLIF) for treating pyogenic lumbar spondylodiscitis.
  
  
  
  Retrospective analysis was performed on prospectively collected data of 27 consecutive cases of lumbar pyogenic spondylodiscitis treated with posterior instrumentation and TLIF between January 2009 and December 2012. Cases were analysed for safety, radiological and clinical outcomes of transforaminal interbody fusion using bone graft ± titanium cages. Interbody metallic cages with bone graft were used in 17 cases and ten cases used only bone graft. Indications for surgical treatment were failed conservative management in 17, neurodeficit in six and significant bony destruction in four.
  
  
  
  There were no cases reporting cage migration, loosening, pseudoarthrosis or recurrence of infection at a mean follow-up of 30 months. Clinical outcomes were assessed using Kirkaldy-Willis criteria, which showed 14 excellent, nine good, three fair and one poor result. Mean focal deformity improved with the use of bone graft ± interbody cages, and the deformity correction was maintained at final follow-up. Mean pre-operative focal lordosis for the graft group was 8.5° (2-16.5°), which improved to 10.9 °(3.3-16°); mean pre-operative focal lordosis in the group treated with cages was 6.7 °(0-15°), which improved to 7°(0-15°) .
  
  
  
  TLIFs with cages in patients with pyogenic lumbar spondylodiscitis allows for acceptable clearance of infection, satisfactory deformity correction with low incidence of cage migration, loosening and infection recurrence.
authors.affiliation: Department of Spine Surgery, Ganga Hospital, 313, Mettupalayam road, Coimbatore, India, PIN 641043.
authors.forename: Ajoy Prasad
authors.initials: AP
authors.lastname: Shetty
authors.affiliation: Department of Spine Surgery, Ganga Hospital, 313, Mettupalayam road, Coimbatore, India, PIN 641043.
authors.forename: Siddharth N
authors.initials: SN
authors.lastname: Aiyer
authors.affiliation: Department of Spine Surgery, Ganga Hospital, 313, Mettupalayam road, Coimbatore, India, PIN 641043.
authors.forename: Rishi Mugesh
authors.initials: RM
authors.lastname: Kanna
authors.affiliation: Department of Spine Surgery, Ganga Hospital, 313, Mettupalayam road, Coimbatore, India, PIN 641043.
authors.forename: Anupama
authors.initials: A
authors.lastname: Maheswaran
authors.affiliation: Department of Spine Surgery, Ganga Hospital, 313, Mettupalayam road, Coimbatore, India, PIN 641043. rajasekaran.orth@gmail.com.
authors.forename: Shanmuganathan
authors.initials: S
authors.lastname: Rajasekaran
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015299:Discitis / Q000601:surgery*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Metallic cages; Pyogenic infection; Spondylodiscitis; Titanium cages; Transforaminal interbody fusion