title: A novel colonoscope with panoramic visualization detected more simulated polyps than conventional colonoscopy in a live swine model.
abstract: OBJECTIVE
  The Aer-O-Scope™ Colonoscope System (AOS) combines panoramic 360° view with standard forward view. We assessed the AOS's ability to identify lesions implanted in live swine, compared to conventional colonoscopy (CC).
  
  
  METHODS
  Twelve swine colons were surgically ligated and beads sewn within. Five procedures (3 AOS and 2 CC) were performed on each swine and findings reported. Physicians were blinded to number, size, and color of beads. The sequence of procedures and physicians was randomized. Pigs, physicians, and colonoscopes were randomly alternated between examination rooms, maintaining physician blindness. Two independent blinded physicians interpreted procedure videos offline.
  
  
  RESULTS
  A total of 259 /273 (94.9 %) of lesions were visualized by AOS compared to 158 /182 with CC (86.8 %) (P = 0.002). Miss rates of lesions ≥ 6 mm were 2.6 % and 10.5 %, respectively (P = 0.022), and 6.9 % and 15.1 %, respectively, for lesions < 6 mm (P = 0.031). Mean agreement between AOS and CC for lesion detection was 88.3 %. The benefit of AOS was maintained in offline video review.
  
  
  CONCLUSIONS
  AOS, featuring panoramic 360° view, demonstrated high detection rates for simulated colonic lesions in a live swine model.
authors.affiliation: Tel Aviv Medical Center, Tel-Aviv, Israel.- ; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Nathan
authors.initials: N
authors.lastname: Gluck
authors.affiliation: Tel Aviv Medical Center, Tel-Aviv, Israel.- ; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Sigal
authors.initials: S
authors.lastname: Fishman
authors.affiliation: Tel Aviv Medical Center, Tel-Aviv, Israel.- ; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Alaa
authors.initials: A
authors.lastname: Melhem
authors.affiliation: GI View Ltd, Ramat Gan, Israel.
authors.forename: Sharon
authors.initials: S
authors.lastname: Goldfarb
authors.affiliation: Tel Aviv Medical Center, Tel-Aviv, Israel.- ; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Zamir
authors.initials: Z
authors.lastname: Halpern
authors.affiliation: Tel Aviv Medical Center, Tel-Aviv, Israel.- ; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Erwin
authors.initials: E
authors.lastname: Santo