title: Epidemiology and risk factors for venous thromboembolism in lung cancer.
abstract: OBJECTIVE
  Cancer is a strong risk factor for venous thromboembolism (VTE). In patients with lung cancer VTE is a significant cause for morbidity and mortality. The purpose of the review is to summarize the epidemiology of thrombotic events, risk factors for VTE and the clinical impact of VTE in patients with lung cancer.
  
  
  RESULTS
  The rates of VTE in lung cancer patients vary according to different types of investigations, and reach 7 to 13%, including a significant number of unsuspected pulmonary emboli. Risk factors for VTE in patients with lung cancer can be basically divided into three categories: patient, tumor, and treatment related. In addition, a number of biomarkers have been described to be associated with VTE risk (e.g., D-dimer).
  
  
  CONCLUSIONS
  Knowledge about the epidemiology, risk factors, and prognostic value of VTE in lung cancer could help to prevent thrombotic complications and improve management of patients with lung cancer.
authors.affiliation: aDepartment of Medicine I, Clinical Division of Haematology and Haemostaseology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria bIstanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Cihan
authors.initials: C
authors.lastname: Ay
authors.forename: Umut Kaan
authors.initials: UK
authors.lastname: Ünal
mesh_terms: D015415:Biomarkers / Q000032:analysis; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology / Q000473:pathology*; D012307:Risk Factors; D054556:Venous Thromboembolism / Q000150:complications / Q000453:epidemiology*; D020246:Venous Thrombosis / Q000150:complications / Q000453:epidemiology*
chemical_list: D015415:Biomarkers