title: Upcoming innovations in lung cancer immunotherapy: focus on immune checkpoint inhibitors.
abstract: For decades, immunotherapy strategies have failed to succeed in lung cancer. However, the recent success of immune checkpoint inhibitors and the progress in the understanding of the immunobiology of lung cancer have changed this paradigm. Here we review ongoing clinical trials and recent results obtained with these novel lung cancer immunotherapies.
authors.affiliation: 114 Rue Edouard Vaillant, 94805 Villejuif Cedex, France. sandrine.aspeslagh@gustaveroussy.fr.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Aspeslagh
authors.affiliation: IGustave Roussy, Université Paris-Saclay, F-94805 Villejuif, France; INSERM U1015, GRCC, F-94805 Villejuif, France.
authors.forename: Aurélien
authors.initials: A
authors.lastname: Marabelle
authors.affiliation: IGustave Roussy, Université Paris-Saclay, F-94805 Villejuif, France.
authors.forename: Jean-Charles
authors.initials: JC
authors.lastname: Soria
authors.affiliation: IGustave Roussy, Université Paris-Saclay, F-94805 Villejuif, France.
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Armand
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D019496:Cancer Vaccines / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007155:Immunologic Factors / Q000009:adverse effects / Q000627:therapeutic use*; D007167:Immunotherapy / Q000009:adverse effects / Q000379:methods*; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D019496:Cancer Vaccines; D007155:Immunologic Factors
keywords: Immune checkpoint inhibitors; immunotherapy; lung cancer; vaccines