title: [Research Progress in the Core Proteins of the Classical Swine Fever Virus].
abstract: The core protein (CP) of the classical swine fever virus (CSFV) is one of its structural proteins. Apart from forming the nucleocapsid to protect internal viral genomic RNA, this protein is involved in transcriptional regulation. Also, during viral infection, the CP is involved in interactions with many host proteins. In this review, we combine study of this protein with its disorders, structural/functional characteristics, as well as its interactions with the non-structural proteins NS3, NS5B and host proteins such as SUMO-1, UBC9, OS9 and IQGAP1. We also summarize the important part played by the CP in CSFV pathogenicity, virulence and replication of genomic RNA. We also provide guidelines for further studies in the CP of the CSFV.
authors.forename: Yuzhen
authors.initials: Y
authors.lastname: Hou
authors.forename: Dantong
authors.initials: D
authors.lastname: Zhao
authors.forename: Guoying
authors.initials: G
authors.lastname: Liu
authors.forename: Fan
authors.initials: F
authors.lastname: He
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Shaoyin
authors.initials: S
authors.lastname: Fu
authors.forename: Yongqing
authors.initials: Y
authors.lastname: Hao
authors.forename: Wenguang
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000818:Animals; D006691:Classical Swine Fever / Q000821:virology*; D006692:Classical Swine Fever Virus / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity; D016679:Genome, Viral; D013552:Swine; D014758:Viral Core Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D014774:Virulence
chemical_list: D014758:Viral Core Proteins