title: [Bone quality and strength relating with bone remodeling].
abstract: The bone has the functions of mineral reservoir and mechanical support as skeleton. Bone remodeling is the adult mode of bone metabolism, replacing old bone tissue to new one. Bone strength is determined by bone volume, structure and quality such as micro damage, degree of mineralization and collagen cross linkage, which are all controlled by bone remodeling. Bone strength decreases under high turn-over condition by decreasing bone volume and deterioration of bone structure, which also decreases under low turn-over condition by increased micro damage, increasing mineralization and AGE collagen cross linkage.
authors.affiliation: Department of Bone & Joint Surgery, Seirei Hamamatsu General Hospital, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Mori
mesh_terms: D000375:Aging / Q000473:pathology; D015519:Bone Density; D016723:Bone Remodeling / Q000502:physiology*; D001842:Bone and Bones / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D002113:Calcification, Physiologic / Q000502:physiology; D003094:Collagen / Q000378:metabolism; D006801:Humans
chemical_list: D003094:Collagen