title: Sacrococcygeal teratoma in a female newborn with clinical features of trisomy 13: a case report from Central Africa.
abstract: BACKGROUND
  The objective of this report is to describe the first patient presenting clinical features of trisomy 13 in association with a sacrococcygeal teratoma.
  
  
  METHODS
  We present the case of a Congolese female infant born with bilateral cleft lip and palate, hypotelorism, microcephaly, and capillary hemangioma on her face. She presented with a large sacrococcygeal mass (15.0 cm ×12.0 cm ×5.0 cm) with a cystic consistency and a positive transillumination.
  
  
  CONCLUSIONS
  This observation suggests that overexpression of certain genes on chromosome 13 may lead to tumor formation from remnant cells of Hensen's node.
authors.affiliation: Department of Paediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo ; Center for Human Genetics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
authors.forename: Toni Kasole
authors.initials: TK
authors.lastname: Lubala
authors.affiliation: Department of Paediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
authors.forename: Olivier
authors.initials: O
authors.lastname: Mukuku
authors.affiliation: Department of Paediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo ; Center for Human Genetics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
authors.forename: Mick Pongombo
authors.initials: MP
authors.lastname: Shongo
authors.affiliation: Department of Paediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
authors.forename: Augustin Mulangu
authors.initials: AM
authors.lastname: Mutombo
authors.affiliation: Department of Paediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
authors.forename: Nina
authors.initials: N
authors.lastname: Lubala
authors.affiliation: Department of Paediatrics, Faculty of Medicine, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo.
authors.forename: Oscar Numbi
authors.initials: ON
authors.lastname: Luboya
authors.affiliation: Department of Paediatrics and Centre for Human Genetics, University Hospital, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
authors.forename: Prosper
authors.initials: P
authors.lastname: Lukusa-Tshilobo
keywords: Hensens’s Node; Patau syndrome; sacrococcygeal; teratoma