title: Human Foetal Mesenchymal Stem Cells.
abstract: Finding suitable cell sources is one of the main challenges in regenerative medicine. In addition to improving the dysfunctional tissue requiring reconstruction, low immunogenicity is beneficial. Mesenchymal stem cells (MSCs) are immune-privileged multipotent stromal cells that can easily multiply and differentiate along many lineages with a minimal oncogenic risk. MSCs derived from foetal tissues present characteristics that suggest an even stronger cell therapeutic potential in comparison to adult MSCs. Due to these characteristics, they have been and are currently being tested in clinical trials for a diverse variety of disorders.
authors.affiliation: Division of Obstetrics and Gynaecology and Centre for Haematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: Cecilia.Gotherstrom@ki.se.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Götherström
mesh_terms: D053686:Fetal Stem Cells / Q000166:cytology* / Q000637:transplantation; D046128:Fetal Therapies; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D039902:Multipotent Stem Cells / Q000166:cytology / Q000637:transplantation; D010013:Osteogenesis Imperfecta / Q000628:therapy*; D044968:Regenerative Medicine
keywords: foetal stem cells; mesenchymal stem cells; multipotent mesenchymal stromal cells; osteogenesis imperfecta; perinatal stem cells