title: Alzheimer disease. Donepezil and nursing home placement--benefits and costs.
abstract: The recent DOMINO-AD trial suggests that continued treatment with donepezil delays nursing home placement for patients with severe Alzheimer disease, but more work is needed to support strong conclusions about whether the benefits outweigh the costs.
authors.affiliation: Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institute, SE-171 77, Stockholm, Sweden.
authors.forename: Vesna
authors.initials: V
authors.lastname: Jelic
authors.affiliation: Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institute, SE-171 77, Stockholm, Sweden.
authors.forename: Bengt
authors.initials: B
authors.lastname: Winblad
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy*; D005260:Female; D006707:Homes for the Aged; D006801:Humans; D007189:Indans / Q000627:therapeutic use*; D008297:Male; D008559:Memantine / Q000627:therapeutic use*; D018697:Nootropic Agents / Q000627:therapeutic use*; D009735:Nursing Homes; D010880:Piperidines / Q000627:therapeutic use*
chemical_list: D007189:Indans; D018697:Nootropic Agents; D010880:Piperidines; D008559:Memantine