title: Fiber optic profenofos sensor based on surface plasmon resonance technique and molecular imprinting.
abstract: A successful approach for the fabrication and characterization of an optical fiber sensor for the detection of profenofos based on surface plasmon resonance (SPR) and molecular imprinting is introduced. Molecular imprinting technology is used for the creation of three dimensional binding sites having complementary shape and size of the specific template molecule over a polymer for the recognition of the same. Binding of template molecule with molecularly imprinted polymer (MIP) layer results in the change in the dielectric nature of the sensing surface (polymer) and is identified by SPR technique. Spectral interrogation method is used for the characterization of the sensing probe. The operating profenofos concentration range of the sensor is from 10(-4) to 10(-1)µg/L. A red shift of 18.7 nm in resonance wavelength is recorded for this profenofos concentration range. The maximum sensitivity of the sensor is 12.7 nm/log (µg/L) at 10(-4)µg/L profenofos concentration. Limit of detection (LOD) of the sensor is found to be 2.5×10(-6)µg/L. Selectivity measurements predict the probe highly selective for the profenofos molecule. Besides high sensitivity due to SPR technique and selectivity due to molecular imprinting, proposed sensor has numerous other advantages like immunity to electromagnetic interference, fast response, low cost and capability of online monitoring and remote sensing of analyte due to the fabrication of the probe on optical fiber.
authors.affiliation: Physics Department, Indian Institute of Technology Delhi, New Delhi 110016, India.
authors.forename: Anand M
authors.initials: AM
authors.lastname: Shrivastav
authors.affiliation: Physics Department, Indian Institute of Technology Delhi, New Delhi 110016, India.
authors.forename: Sruthi P
authors.initials: SP
authors.lastname: Usha
authors.affiliation: Physics Department, Indian Institute of Technology Delhi, New Delhi 110016, India. Electronic address: bdgupta@physics.iitd.ernet.in.
authors.forename: Banshi D
authors.initials: BD
authors.lastname: Gupta
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D005336:Fiber Optic Technology / Q000379:methods*; D054802:Molecular Imprinting; D063086:Organothiophosphates / Q000737:chemistry / Q000302:isolation & purification*; D011108:Polymers / Q000737:chemistry; D020349:Surface Plasmon Resonance / Q000379:methods*
chemical_list: D063086:Organothiophosphates; D011108:Polymers; C024273:profenofos
keywords: Molecular imprinting; Optical fiber; Pesticides; Profenofos; Sensor; Surface plasmon resonance