title: Bioengineered riboflavin in nanotechnology.
abstract: Riboflavin (RF) is an essential water-soluble vitamin with unique biological and physicochemical properties such as transporterspecific cell internalization, implication in redox reactions, fluorescence and photosensitizing. Due to these features RF attracted researchers in various fields from targeted drug delivery and tissue engineering to optoelectronics and biosensors. In this review we will give a brief reminder of RF chemistry, its optical, photosensitizing properties, RF transporter systems and its role in pathologies. We will point a special attention on the recent findings concerning RF applications in nanotechnologies such as RF functionalized nanoparticles, polymers, biomolecules, carbon nanotubes, hydrogels and implants for tissue engineering.
authors.affiliation: MMBE Team, UMR 5248 CBMN, Bordeaux University, Pessac, France.
authors.forename: N
authors.initials: N
authors.lastname: Beztsinna
authors.affiliation: MMBE Team, UMR 5248 CBMN, Bordeaux University, Pessac, France.
authors.forename: M
authors.initials: M
authors.lastname: Solé
authors.affiliation: MMBE Team, UMR 5248 CBMN, Bordeaux University, Pessac, France.
authors.forename: N
authors.initials: N
authors.lastname: Taib
authors.affiliation: MMBE Team, UMR 5248 CBMN, Bordeaux University, Pessac, France. Electronic address: isabelle.berque-bestel@u-bordeaux.fr.
authors.forename: I
authors.initials: I
authors.lastname: Bestel
mesh_terms: D000818:Animals; D001698:Biomedical Engineering / Q000379:methods*; D015374:Biosensing Techniques / Q000379:methods; D006801:Humans; D008958:Models, Molecular; D050997:Nanomedicine / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry / Q000378:metabolism; D036103:Nanotechnology / Q000379:methods*; D017319:Photosensitizing Agents / Q000737:chemistry* / Q000378:metabolism; D012256:Riboflavin / Q000737:chemistry* / Q000378:metabolism; D023822:Tissue Engineering / Q000379:methods; D014803:Vitamin B Complex / Q000737:chemistry* / Q000378:metabolism
chemical_list: D017319:Photosensitizing Agents; D014803:Vitamin B Complex; D012256:Riboflavin
keywords: Bioconjugates; Biosensors; Nanodevices; Optoelectronics; Riboflavin; Tissue engineering