title: An attempt to estimate the minimal number of Poles infected and treated for malaria in Poland and abroad.
abstract: BACKGROUND
  Malaria is one of the three most dangerous infectious diseases in the world. According to official statistics, there are a few dozen cases in Poland annually while the number of Poles treated abroad or self-treating remains unknown. Poland has been declared to be malaria-free since 1963 and nowadays all cases are imported. The aim of the study is to determine the minimal number of malaria cases in Poles at home and abroad in the last decade.
  
  
  METHODS
  The medical records of 4,710 patients tested for malaria in the Department of Tropical Parasitology in the years 2003-2012 were analysed. Two spreadsheets were created, which only included people with a history of malaria diagnosed in the reference centre where indirect immunofluorescent-antibody assay (IFA) for Plasmodium falciparum antigen proved positive. The minimum number of Poles who have had malaria at home and abroad was calculated on the basis of positive IFA results; the rate of all treated malaria patients in Poland in relation to those treated in the reference centre and the actual number of Poles with malaria diagnosed at home was calculated.
  
  
  RESULTS
  A group of 376 people with positive serologic tests results in indirect immunofluorescent antibody assay with titre ≥ 1:20 were received, including 227 patients with positive serologic results with titre ≥ 1:80. The rate of the overall number of malaria cases in Poland compared to the number of malaria cases in the University Centre for Maritime and Tropical Medicine Hospital was determined as 3.47:1. It was demonstrated that every year at least 174 to 211 Poles staying abroad may suffer from malaria.
  
  
  CONCLUSIONS
  This is the first attempt to estimate the minimal number of Poles infected and treated for malaria in Poland and abroad. The estimated number is 8-10 times greater than the number of registered cases in Poland.
authors.affiliation: Department of Tropical and Parasitic Diseases, University Centre for Maritime and Tropical Medicine, Gdynia, Poland Department of Tropical Parasitology, Institute of Maritime and Tropical Medicine in Gdynia, Medical University of Gdansk, Poland. anna.kuna@gumed.edu.pl.
authors.forename: Anna
authors.initials: A
authors.lastname: Kuna
authors.forename: Beata
authors.initials: B
authors.lastname: Szostakowska
authors.forename: Wacław L
authors.initials: WL
authors.lastname: Nahorski
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Stępień
authors.forename: Danuta
authors.initials: D
authors.lastname: Kowalczyk
authors.forename: Joanna
authors.initials: J
authors.lastname: Stańczak
authors.forename: Przemysław
authors.initials: P
authors.lastname: Myjak
mesh_terms: D006801:Humans; D008288:Malaria / Q000188:drug therapy* / Q000453:epidemiology*; D008485:Medical Audit; D011044:Poland / Q000453:epidemiology; D012189:Retrospective Studies; D012648:Self Care
keywords: malaria; seroepidemiologic studies