title: Fine-Needle Aspiration, Touch Imprint, and Crush Preparation Cytology for Diagnosing Thyroid Malignancies in Thyroid Nodules.
abstract: Several methods are used to evaluate the thyroid nodules. The aim of this study was to determine the sensitivity, specificity, false positive and negative rates, positive predictive value (PPV), and negative predictive value (NPV) of touch imprint, crush preparation, and fine-needle aspiration (FNA) methods. This cross-sectional study was done in Shohada-ye Ashayer University Hospital in Khorramabad. All the patients who underwent thyroid surgery due to thyroid nodules in this hospital between March and September 2011 were evaluated. The thyroid nodules of all the patients were evaluated by touch imprint, crush preparation, FNA, and permanent pathology methods. Finally, the results of the first three methods were compared with the result of permanent pathology method. The mean age of 104 patients who underwent thyroid surgery was 42.6 ± 11.9 years old. Based on permanent pathology, touch imprint, crush preparation, and FNA methods, 15.3, 6.25, 6.25, and 4.4 % of thyroid nodules were malignant, respectively. Sensitivity, specificity, false positive rate, false negative rate, PPV, and NPV of FNA biopsy were 62.5, 100, 0, 37.5, 100, and 95.3 %, respectively. Also, sensitivity, specificity, false positive rate, false negative rate, PPV, and NPV of touch imprint and crush preparation were equal and were 80, 100, 0, 20, 100, and 96.7 %, respectively. Using touch imprint and crush preparation in evaluation of thyroid nodules for rapid evaluation of these nodules in operating rooms seems to be logical, and it can prevent further surgeries.
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran ; Clinical Research Center, Shohada-ye Ashayer University Hospital, Enghelab Street, Khorramabad, Lorestan Iran.
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Ahmadinejad
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Asghar
authors.initials: A
authors.lastname: Aliepour
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Khatereh
authors.initials: K
authors.lastname: Anbari
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Mojhgan
authors.initials: M
authors.lastname: Kaviani
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Hasan
authors.initials: H
authors.lastname: Ganjizadeh
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Sedigheh
authors.initials: S
authors.lastname: Nadri
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Niloufar
authors.initials: N
authors.lastname: Foroutani
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Masoumeh
authors.initials: M
authors.lastname: Meysami
authors.affiliation: Clinical Research Center, Shohada-ye Ashayer University Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Vahid
authors.initials: V
authors.lastname: Almasi
keywords: Crush preparation; Cytology; Fine-needle aspiration; Thyroid nodule; Touch imprint