title: Renal Transplant Arterial Stenosis Treated With Bare-Metal Versus Drug-Eluting Stents: Comparison of Treatment Outcomes.
abstract: BACKGROUND
  This study aims to evaluate outcomes of bare-metal stents (BMS) versus drug-eluting stents (DES) in patients who undergo stenting for transplant renal arterial stenosis.
  
  
  METHODS
  We retrospectively reviewed records of renal transplantation patients who underwent transplant renal arterial stenting from September 2009 to September 2013. All stents greater than 5 mm were excluded to allow for equivalent comparison between the DES and BMS groups. Statistical comparisons were performed using a two-tailed Fischer exact test, and analysis of continuous variables was analyzed using a one-way analysis of variance.
  
  
  RESULTS
  The final study population included a total of 18 patients who received either BMS or DES (11 and 7 patients, respectively) for transplant renal arterial stenosis. The most common indications for stenting were increasing creatinine level and abnormal Doppler velocities. There were more re-interventions with BMS (n = 4/11) than DES (n = 0/7), but the trend was not statistically significant (P = .12). Three patients who received BMS had a clinically significant decrease in blood pressure versus 4 in the DES group (P = .33). Six patients who received BMS had a clinically significant decrease in creatinine level versus 3 in the DES group (P = 1.0).
  
  
  CONCLUSIONS
  There is an absolute but not statistically significant difference in the incidence of restenosis requiring repeat intervention between the BMS and DES groups. No difference was detected in clinical success as measured by decreases in blood pressure or creatinine. Future larger studies are needed to corroborate these findings.
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: R F
authors.initials: RF
authors.lastname: Hanna
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York. Electronic address: frankhao1@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Hao
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: C F
authors.initials: CF
authors.lastname: Kraus
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: G
authors.initials: G
authors.lastname: Mitsopoulos
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: G E
authors.initials: GE
authors.lastname: Goldstein
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: J
authors.initials: J
authors.lastname: Weintraub
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: D
authors.initials: D
authors.lastname: Sperling
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: J
authors.initials: J
authors.lastname: Susman
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: P
authors.initials: P
authors.lastname: Schlossberg
authors.affiliation: Department of Radiology, Columbia University Medical Center, New York, New York.
authors.forename: V
authors.initials: V
authors.lastname: Sheynzon
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D003404:Creatinine / Q000032:analysis; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000601:surgery*; D012189:Retrospective Studies; D015607:Stents
chemical_list: D003404:Creatinine