title: Cu(I)-catalyzed N,N'-diarylation of natural diamines and polyamines with aryl iodides.
abstract: The Cu(I)-catalyzed N,N'-diarylation of natural diamines and polyamines such as putrescine, cadaverine, spermine, spermidine and their homologues is described. Aryl iodides bearing electron-donating and electron-withdrawing groups have been employed in the study. The CuI/2-(isobutyryl)cyclohexanone/DMF catalytic system has found to be more efficient in the diarylation of diamines and spermine while the CuI/L-proline/EtCN system proved to be preferable for the diarylation of other tri- and tetraamines like spermidine, norspermidine and norspermine.
authors.affiliation: Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow, 119991, Russia.
authors.forename: Svetlana Petrovna
authors.initials: SP
authors.lastname: Panchenko
authors.affiliation: Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow, 119991, Russia.
authors.forename: Alexei Dmitrievich
authors.initials: AD
authors.lastname: Averin
authors.affiliation: Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow, 119991, Russia.
authors.forename: Maksim Viktorovich
authors.initials: MV
authors.lastname: Anokhin
authors.affiliation: Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow, 119991, Russia.
authors.forename: Olga Aleksandrovna
authors.initials: OA
authors.lastname: Maloshitskaya
authors.affiliation: Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow, 119991, Russia.
authors.forename: Irina Petrovna
authors.initials: IP
authors.lastname: Beletskaya
keywords: amination; aryl amines; aryl iodides; copper catalysis; polyamines