title: Yield of double-balloon enteroscopy in the diagnosis and treatment of small bowel strictures.
abstract: BACKGROUND
  Small bowel strictures are common in gastroenterology practice. We report diagnostic and therapeutic yield of double-balloon enteroscopy for small bowel strictures.
  
  
  METHODS
  Retrospective study of 71 consecutive patients who were found to have small bowel stricture at the time of double-balloon enteroscopy.
  
  
  RESULTS
  During double-balloon enteroscopy, stricture identification and tissue sampling were possible in all 71 cases. Surgical pathology reported aetiology as non-steroidal anti-inflammatory drugs (32%), non-specific (21%), Crohn's disease (21%), radiation-induced (9%), tumour (10%), anastomotic (4%), celiac disease (1%), and surgical adhesions (1%). Sixteen patients (23%) underwent balloon dilation. Sensitivity of abdominal computed-tomography and video-capsule endoscopy for strictures based on double balloon enteroscopy findings was 61% and 43%, respectively.
  
  
  CONCLUSIONS
  Double-balloon enteroscopy was safe and effective to access small bowel stricture with direct visualization and tissue sampling or for therapeutic balloon dilation. Given low sensitivity with conventional computed-tomography and/or video-capsule endoscopy for small bowel stricture, double-balloon enteroscopy can be considered if clinical suspicion is high.
authors.affiliation: Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
authors.forename: Paul T
authors.initials: PT
authors.lastname: Kroner
authors.affiliation: Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
authors.forename: Bhaumik S
authors.initials: BS
authors.lastname: Brahmbhatt
authors.affiliation: Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Bartel
authors.affiliation: Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Stark
authors.affiliation: Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA. Electronic address: Lukens.Frank@mayo.edu.
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Lukens
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D053704:Capsule Endoscopy; D003424:Crohn Disease / Q000150:complications; D058582:Double-Balloon Enteroscopy; D005260:Female; D005431:Florida; D006801:Humans; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology*; D007421:Intestine, Small / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D014057:Tomography, X-Ray Computed
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal
keywords: Balloon-assisted enteroscopy; Double-balloon enteroscopy; Small bowel stricture