title: [Risk factors research for overt/non-overt die in abdominal aortic aneurysm patients undergoing endovascular aneurysm repair].
abstract: OBJECTIVE
  To determine risk factors of overt/non-overt disseminated intravascular coagulation (DIC) in abdominal aortic aneurysm (AAA) patients undergoing endovascular aneurysm repair (EVAR).
  
  
  METHODS
  In a retrospective study, 117 patients undergoing selective EVAR for AAA were investigated for overt/non-overt DIC from June 1st 2013 to December 31 2014. The following parameters were reviewed: D-dimer, Platelet count, fibrinogen and prothrombin time (PT) at before operation and 1, 2, and 7 days after operation. Non-overt DIC was defined as International Society on Thrombosis and Hemostasis (ISTH) score between 2 and 5, and overt DIC score ≥5. Factors associated with overt/non-overt DIC were identified by stepwise Logistic regression.
  
  
  RESULTS
  Among 117 patients, who received EVAR for AAA, 3 patients (2. 5%) were diagnosed as overt DIC and 31 patients (26. 5%) were diagnosed as non-overt DIC. Univariate analysis showed significant risk factors for overt/non-overt DIC were aging, operating duration, blood loss, renal dysfunction and endoleak (P <0. 05). Stepwise Logistic regression showed that independent risk factors for overt/non-overt DIC were endoleak (B = 2. 118, SE = 0. 917, Wald =5. 335,P =0. 021), renal dysfunction (B = 2. 135, SE =0. 797, Wald = 7. 183, P = 0. 007) and operating duration (B = 0. 021, SE = 0. 006, Wald = 11. 126, P = 0. 001).
  
  
  CONCLUSIONS
  Independent risk factors for non-overt DIC in patients who received EVAR for AAA are endoleak, renal dysfunction and operating duration.
authors.forename: Rong
authors.initials: R
authors.lastname: Zeng
authors.forename: Wei
authors.initials: W
authors.lastname: Ye
authors.forename: Bao
authors.initials: B
authors.lastname: Liu
authors.forename: Leng
authors.initials: L
authors.lastname: Ni
authors.forename: Changwei
authors.initials: C
authors.lastname: Liu
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Li
authors.forename: Yuehong
authors.initials: Y
authors.lastname: Zheng
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Song
authors.forename: Jiang
authors.initials: J
authors.lastname: Shao
authors.forename: Yuexin
authors.initials: Y
authors.lastname: Chen
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.forename: Zhili
authors.initials: Z
authors.lastname: Liu
mesh_terms: D017544:Aortic Aneurysm, Abdominal; D001780:Blood Coagulation Tests; D004211:Disseminated Intravascular Coagulation; D057867:Endoleak; D057510:Endovascular Procedures; D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen; D006801:Humans; D016015:Logistic Models; D010976:Platelet Count; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D005340:Fibrinogen