title: Regulating the High: Cognitive and Neural Processes Underlying Positive Emotion Regulation in Bipolar I Disorder.
abstract: Although it is well established that Bipolar Disorder (BD) is characterized by excessive positive emotionality, the cognitive and neural processes that underlie such responses are unclear. We addressed this issue by examining the role that an emotion regulatory process calledself-distancingplays in two potentially different BD phenotypes-BD with vs. without a history of psychosis-and healthy individuals. Participants reflected on a positive autobiographical memory and then rated their level of spontaneous self-distancing. Neurophysiological activity was continuously monitored using electroencephalogram. As predicted, participants with BD who have a history of psychosis spontaneously self-distanced less and displayed greater neurophysiological signs of positive emotional reactivity compared to the other two groups. These findings shed light on the cognitive and neural mechanisms underlying excessive positive emotionality in BD. They also suggest that individuals with BD who have a history of psychosis may represent a distinct clinical phenotype characterized by dysfunctional emotion regulation.
authors.affiliation: University of Michigan, Ann Arbor.
authors.forename: Jiyoung
authors.initials: J
authors.lastname: Park
authors.affiliation: University of California, Berkeley.
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Ayduk
authors.affiliation: University of Michigan, Ann Arbor.
authors.forename: Lisa
authors.initials: L
authors.lastname: O'Donnell
authors.affiliation: Beth Israel Deaconess Medical Center.
authors.forename: Jinsoo
authors.initials: J
authors.lastname: Chun
authors.affiliation: Yale University.
authors.forename: June
authors.initials: J
authors.lastname: Gruber
authors.affiliation: University of Michigan, Ann Arbor.
authors.forename: Masoud
authors.initials: M
authors.lastname: Kamali
authors.affiliation: University of Michigan, Ann Arbor.
authors.forename: Melvin
authors.initials: M
authors.lastname: McInnis
authors.affiliation: University of Michigan, Ann Arbor.
authors.forename: Patricia
authors.initials: P
authors.lastname: Deldin
authors.affiliation: University of Michigan, Ann Arbor.
authors.forename: Ethan
authors.initials: E
authors.lastname: Kross
keywords: Bipolar Disorder; emotion regulation; psychosis history; self-distancing