title: Late recurrent peripheral upper limb ischemia after non-union of a clavicle fracture.
abstract: A 74-year-old woman was referred to our hospital due to recurrent episodes of upper limb ischemia. Her past medical history included a clavicle non-union developed after a clavicle midshaft fracture that had occurred 30 years previously. After a long asymptomatic period, she started showing symptoms of chronic ischemia to the left arm that were misdiagnosed. Thoracic outlet syndrome (TOS) is a rare but possible complication of mal-union and non-union of clavicle fractures; symptoms related to arterial involvement (ATOS) amount to less than 1% of all existing forms of thoracic outlet syndrome. In case of clavicle non-union, local instability plays a key role in determining the initial injury to the vessels and the recurrence of symptoms. Restoration of local bone stability and anatomy, obtained by compression plating and autologous bone grafting, combined with an appropriate vascular surgery, is essential to achieve a clinical resolution of symptoms and to avoid the recurrence of symptomatology as seen in the herein case.
authors.affiliation: Orthopaedic and Trauma Unit, Department of Emergency, IRCCS AOU San Martino - IST, Largo Rosanna Benzi 10, 16132 Genoa, Italy. Electronic address: dr.marcostella@gmail.com.
authors.forename: Marco
authors.initials: M
authors.lastname: Stella
authors.affiliation: Orthopaedic and Trauma Unit, Department of Emergency, IRCCS AOU San Martino - IST, Largo Rosanna Benzi 10, 16132 Genoa, Italy.
authors.forename: Emmanuele
authors.initials: E
authors.lastname: Santolini
authors.affiliation: Orthopaedic and Trauma Unit, Department of Emergency, IRCCS AOU San Martino - IST, Largo Rosanna Benzi 10, 16132 Genoa, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Briano
authors.affiliation: Orthopaedic and Trauma Unit, Department of Emergency, IRCCS AOU San Martino - IST, Largo Rosanna Benzi 10, 16132 Genoa, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Santolini
mesh_terms: D000368:Aged; D001860:Bone Plates / Q000009:adverse effects; D002968:Clavicle / Q000293:injuries* / Q000601:surgery*; D003951:Diagnostic Errors; D005260:Female; D005593:Fracture Fixation, Internal / Q000009:adverse effects / Q000379:methods*; D050723:Fractures, Bone / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D013348:Subclavian Artery / Q000601:surgery*; D013901:Thoracic Outlet Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome
keywords: ATOS; TOS; arterial thoracic outlet syndrome; autologous bone graft; clavicle non-union; internal fixation; plate osteosynthesis; subclavian artery; thoracic outlet syndrome; upper limb chronic ischemia