title: Neurosensory Symptom Complexes after Acute Mild Traumatic Brain Injury.
abstract: Mild Traumatic Brain Injury (mTBI) is a prominent public health issue. To date, subjective symptom complaints primarily dictate diagnostic and treatment approaches. As such, the description and qualification of these symptoms in the mTBI patient population is of great value. This manuscript describes the symptoms of mTBI patients as compared to controls in a larger study designed to examine the use of vestibular testing to diagnose mTBI. Five symptom clusters were identified: Post-Traumatic Headache/Migraine, Nausea, Emotional/Affective, Fatigue/Malaise, and Dizziness/Mild Cognitive Impairment. Our analysis indicates that individuals with mTBI have headache, dizziness, and cognitive dysfunction far out of proportion to those without mTBI. In addition, sleep disorders and emotional issues were significantly more common amongst mTBI patients than non-injured individuals. A simple set of questions inquiring about dizziness, headache, and cognitive issues may provide diagnostic accuracy. The consideration of other symptoms may be critical for providing prognostic value and treatment for best short-term outcomes or prevention of long-term complications.
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.|University of Miami Sports Performance and Wellness Institute, Miami, Florida, United States of America.|Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Hoffer
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.|University of Miami Sports Performance and Wellness Institute, Miami, Florida, United States of America.
authors.forename: Mikhaylo
authors.initials: M
authors.lastname: Szczupak
authors.affiliation: Neurokinetics, Inc, Pittsburgh, Pennsylvania, United States of America.
authors.forename: Alexander
authors.initials: A
authors.lastname: Kiderman
authors.affiliation: Department of Otolaryngology, Madigan Army Medical Center, Tacoma, Washington, United States of America.
authors.forename: James
authors.initials: J
authors.lastname: Crawford
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
authors.forename: Sara
authors.initials: S
authors.lastname: Murphy
authors.affiliation: Department of Otolaryngology, Madigan Army Medical Center, Tacoma, Washington, United States of America.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Marshall
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, United States of America.|University of Miami Sports Performance and Wellness Institute, Miami, Florida, United States of America.
authors.forename: Constanza
authors.initials: C
authors.lastname: Pelusso
authors.affiliation: Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania United States of America.
authors.forename: Carey
authors.initials: C
authors.lastname: Balaban
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000342:Affective Symptoms / Q000209:etiology; D001930:Brain Injuries / Q000150:complications* / Q000175:diagnosis; D016000:Cluster Analysis; D060825:Cognitive Dysfunction / Q000209:etiology; D004244:Dizziness / Q000209:etiology; D004636:Emergency Service, Hospital; D005221:Fatigue / Q000209:etiology; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006261:Headache / Q000209:etiology; D006772:Hospitals, Military; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000209:etiology; D009483:Neuropsychological Tests; D025341:Principal Component Analysis; D011379:Prognosis; D012737:Sex Factors; D011795:Surveys and Questionnaires; D063189:Symptom Assessment; D015599:Trauma Severity Indices; D014724:Vestibular Function Tests; D055815:Young Adult