title: [RISK FACTORS FOR INTRAVESICAL RECURRENCE AFTER SURGICAL MANAGEMENT OF UROTHERIAL CARCINOMA OF THE UPPER URINARY TRACT].
abstract: OBJECTIVE
  To identify risk factors for developing recurrent bladder cancer in patients who underwent surgical resection for urothelial carcinoma of the upper urinary tract.
  
  
  METHODS
  We retrospectively analyzed 322 patients who underwent surgical resection for urothelial carcinoma of the upper urinary tract at the Jikei University Hospital and our affiliated hospitals between January 2005 and July 2011. Univariate and multivariate analyses by using the Cox proportional hazards model were performed to determine the risk factors for intravesical recurrence after nephroureterectomy in these 322 patients.
  
  
  RESULTS
  Of the 322 patients, 111 patients (34.5%) developed recurrent bladder cancer after a median interval of 8.0 months. On multivariate analysis, the presence of a superficial tumor and the presence of a ureteral tumor were independent predictors for intravesical recurrence.
  
  
  CONCLUSIONS
  The risk factors for developing recurrent bladder cancer were the presence of a superficial tumor and the presence of a ureteral tumor. Further investigation is required to evaluate the efficacy of perioperative intravesical therapy for the prevention of intravesical recurrence.
authors.forename: Shoji
authors.initials: S
authors.lastname: Kimura
authors.forename: Jun
authors.initials: J
authors.lastname: Miki
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Tsuduki
authors.forename: Kouichi
authors.initials: K
authors.lastname: Aikawa
authors.forename: Hideomi
authors.initials: H
authors.lastname: Nishikawa
authors.forename: Gen
authors.initials: G
authors.lastname: Ishii
authors.forename: Kenichi
authors.initials: K
authors.lastname: Hata
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Omono
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sasaki
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Shimomura
authors.forename: Hiroki
authors.initials: H
authors.lastname: Yamada
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kimura
authors.forename: Akira
authors.initials: A
authors.lastname: Furuta
authors.forename: Kenta
authors.initials: K
authors.lastname: Miki
authors.forename: Shin
authors.initials: S
authors.lastname: Egawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D014516:Ureteral Neoplasms / Q000473:pathology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000556:secondary*; D013520:Urologic Surgical Procedures