title: MRI-guided epilepsy detection.
abstract: One of the most common neurological brain disorder is epilepsy that happen as an abrupt seizure. Around 30% of patients with epilepsy resist to all forms of medical treatments and, therefore, the removal of epileptic brain tissue is the only solution to get these patients free from chronical seizures. Discovering the epileptic region is a first key into the treatment. In this paper, we introduced a method for epilepsy detection. In this method superparamagnetic nanoparticle, (SPMN) is used as a sensing material in order to investigate the epileptic area. Based on the magnetic field, first they are crossed through the Blood Brain Barrier (BBB). They can cross the blood-brain barrier into the brain by means of magnetic forces. In this study, the optimal force for crossing to the brain and nanoparticles aggregation by means of MRI magnetic field for crossing and weak magnetic field inside the brain have been considered. Nanoparticles aggregation can be used as a marker to increase the contrast of MRI images in the epileptic brain area.
authors.forename: Maysam Z
authors.initials: MZ
authors.lastname: Pedram
authors.forename: Amir
authors.initials: A
authors.lastname: Shamloo
authors.forename: Aria
authors.initials: A
authors.lastname: Alasty
authors.forename: Ebrahim
authors.initials: E
authors.lastname: Ghafar-Zadeh
mesh_terms: D001812:Blood-Brain Barrier / Q000378:metabolism; D001921:Brain / Q000000981:diagnostic imaging*; D003287:Contrast Media / Q000737:chemistry / Q000378:metabolism; D004827:Epilepsy / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D058185:Magnetite Nanoparticles / Q000737:chemistry; D008962:Models, Theoretical; D011859:Radiography
chemical_list: D003287:Contrast Media; D058185:Magnetite Nanoparticles