title: A rare case of myeloid sarcoma presenting as anal fissure.
abstract: Myeloid sarcoma is a tumor composed of myeloblasts occurring at an extramedullary site. It may develop in patients with acute myeloid leukemia, myeloproliferative or myelodysplastic syndrome, sometimes preceding onset of the systemic disease. Frequent sites of myeloid sarcoma are bones or various soft tissues. Gastrointestinal involvement is very rare. We report a unique case of myeloid sarcoma presenting as a painful anal fissure, in a patient with a history of acute myeloid leukemia. The diagnosis was achieved by a surgical excisional biopsy and immunoistochemical staining.
authors.forename: R
authors.initials: R
authors.lastname: Vecchio
authors.forename: E
authors.initials: E
authors.lastname: Intagliata
authors.forename: P F
authors.initials: PF
authors.lastname: Fiumara
authors.forename: L
authors.initials: L
authors.lastname: Villari
authors.forename: S
authors.initials: S
authors.lastname: Marchese
authors.forename: E
authors.initials: E
authors.lastname: Cacciola
mesh_terms: D000368:Aged; D001005:Anus Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D003937:Diagnosis, Differential; D005401:Fissure in Ano / Q000150:complications / Q000209:etiology* / Q000473:pathology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008297:Male; D010146:Pain / Q000209:etiology; D035583:Rare Diseases; D012307:Risk Factors; D023981:Sarcoma, Myeloid / Q000150:complications* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome