title: Expedient synthesis of new cinnoline diones by Ru-catalyzed regioselective unexpected deoxygenation-oxidative annulation of propargyl alcohols with phthalazinones and pyridazinones.
abstract: Ruthenium-catalyzed simple, cascade and one-pot synthesis of cinnoline-fused diones has been carried out by the C-H activation of phthalazinones/pyridazinones accomplished by the unusual deoxygenation of propargyl alcohols. The bond selectivity is accredited to the traceless directing nature of the hydroxyl group of propargyl alcohol. A sequential C-H activation, insertion and deoxy-oxidative annulation has been proposed based on the preliminary mechanistic study.
authors.affiliation: Materials Chemistry Division, School of Advanced Sciences, VIT University, Tamil Nadu 632014, India. velan.g@vit.ac.in.
authors.forename: Subramani
authors.initials: S
authors.lastname: Rajkumar
authors.forename: S
authors.initials: S
authors.lastname: Antony Savarimuthu
authors.forename: Rajendran
authors.initials: R
authors.lastname: Senthil Kumaran
authors.forename: C M
authors.initials: CM
authors.lastname: Nagaraja
authors.forename: Thirumanavelan
authors.initials: T
authors.lastname: Gandhi