title: Mortality and functional status at one-year of follow-up in elderly patients with prolonged ICU stay.
abstract: OBJECTIVE
  To evaluate mortality and functional status at one year of follow-up in patients>75 years of age who survive Intensive Care Unit (ICU) admission of over 14 days.
  
  
  METHODS
  A prospective observational study was carried out.
  
  
  METHODS
  A Spanish medical-surgical ICU.
  
  
  METHODS
  Patients over 75 years of age admitted to the ICU.
  
  
  METHODS
  ICU admission: demographic data, baseline functional status (Barthel index), baseline mental status (Red Cross scale of mental incapacity), severity of illness (APACHE II and SOFA), stay and mortality. One-year follow-up: hospital stay and mortality, functional and mental status, and one-year follow-up mortality.
  
  
  RESULTS
  A total of 176 patients were included, of which 22 had a stay of over 14 days. Patients with prolonged stay did not show more ICU mortality than those with a shorter stay in the ICU (40.9% vs 25.3% respectively, P=.12), although their hospital (63.6% vs 33.8%, P<.01) and one-year follow-up mortality were higher (68.2% vs 41.2%, P=.02). Among the survivors, one-year mortality proved similar (87.5% vs 90.6%, P=.57). These patients presented significantly greater impairment of functional status at hospital discharge than the patients with a shorter ICU stay, and this difference persisted after three months. The levels of independence at one-year follow-up were never similar to baseline. No such findings were observed in relation to mental status.
  
  
  CONCLUSIONS
  Patients over 75 years of age with a ICU stay of more than 14 days have high hospital and one-year follow-up mortality. Patients who survive to hospital admission did not show greater mortality, though their functional dependency was greater.
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España. Electronic address: consuelopintado@yahoo.es.
authors.forename: M C
authors.initials: MC
authors.lastname: Pintado
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.
authors.forename: P
authors.initials: P
authors.lastname: Villa
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.
authors.forename: J
authors.initials: J
authors.lastname: Luján
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.
authors.forename: M
authors.initials: M
authors.lastname: Trascasa
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.
authors.forename: R
authors.initials: R
authors.lastname: Molina
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.
authors.forename: N
authors.initials: N
authors.lastname: González-García
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.
authors.forename: R
authors.initials: R
authors.lastname: de Pablo
mesh_terms: D018806:APACHE; D000368:Aged; D000369:Aged, 80 and over; D003953:Diagnosis-Related Groups; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D057187:Independent Living; D007362:Intensive Care Units; D007902:Length of Stay; D008297:Male; D000073216:Mental Status and Dementia Tests; D063305:Organ Dysfunction Scores; D010351:Patient Discharge; D011446:Prospective Studies; D020127:Recovery of Function; D013030:Spain / Q000453:epidemiology; D016019:Survival Analysis; D062606:Tertiary Care Centers
keywords: Ancianos; Calidad de vida relacionada con la salud; Critical care; Cuidados intensivos; Elderly; Health-related quality of life; Long-term outcome; Prognosis; Pronóstico; Resultado a largo plazo