title: Metal-free arylation of pyrimidines through a photochemical process.
abstract: Pyrimidinyl and pyrazinyl radicals were generated under moderate energetic irradiation conditions (UVA), and proved to be prompt to undergo C-C bond formation processes. Hetero-biaryl derivatives were obtained in good to high yields with highly interesting functional group selectivities. Bis hetero-biaryls were also easily accessible leading to original compounds, ready for further transformations. Experiments supporting radical processes have been reported.
authors.affiliation: Laboratoire de Chimie Organique et Bioorganique EA 4566, Université de Haute-Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse, 3 bis rue Alfred Werner, 68093 Mulhouse Cedex, France. jean-philippe.goddard@uha.fr.
authors.forename: Jonas
authors.initials: J
authors.lastname: Ruch
authors.affiliation: Laboratoire de Chimie Organique et Bioorganique EA 4566, Université de Haute-Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse, 3 bis rue Alfred Werner, 68093 Mulhouse Cedex, France. jean-philippe.goddard@uha.fr.
authors.forename: Ariane
authors.initials: A
authors.lastname: Aubin
authors.affiliation: Laboratoire de Chimie Organique et Bioorganique EA 4566, Université de Haute-Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse, 3 bis rue Alfred Werner, 68093 Mulhouse Cedex, France. jean-philippe.goddard@uha.fr.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Erbland
authors.affiliation: Laboratoire de Chimie Organique et Bioorganique EA 4566, Université de Haute-Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse, 3 bis rue Alfred Werner, 68093 Mulhouse Cedex, France. jean-philippe.goddard@uha.fr.
authors.forename: Audrey
authors.initials: A
authors.lastname: Fortunato
authors.affiliation: Laboratoire de Chimie Organique et Bioorganique EA 4566, Université de Haute-Alsace, Ecole Nationale Supérieure de Chimie de Mulhouse, 3 bis rue Alfred Werner, 68093 Mulhouse Cedex, France. jean-philippe.goddard@uha.fr.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Goddard
mesh_terms: D008670:Metals / Q000737:chemistry*; D055668:Photochemical Processes; D011743:Pyrimidines / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D008670:Metals; D011743:Pyrimidines