title: Treatment outcomes of micropulse transscleral cyclophotocoagulation in advanced glaucoma.
abstract: Glaucoma is the leading cause of irreversible blindness worldwide. The goal of this study was to describe our experience with the novel micropulse transscleral cyclophotocoagulation (MP-TSCPC; IRIDEX IQ810 Laser Systems, CA) in patients with advanced glaucoma. Patients with advanced glaucoma who underwent MP-TSCPC were included in our study. Laser settings were 2000 mW of 810 nm infrared diode laser set on micropulse delivery mode. The laser was delivered over 360° for 100-240 s. The duty cycle was 31.3 %, which translated to 0.5 ms of "on time" and 1.1 ms of "off time." Surgical success was defined as an intraocular pressure (IOP) of 6-21 mmHg or a reduction of IOP by 20 % at the last follow-up visit. Failure was defined as an inability to meet the criteria for success or a need for incisional glaucoma surgery. Nineteen patients underwent MP-TSCPC with mean follow-up of 60.3 days. Mean IOP dropped from 37.9 mmHg preoperatively to 22.7 mmHg at last follow-up, representing a 40.1 % decrease. The success rate for initial treatment was 73.7 % (n = 14). Three patients underwent a second treatment, increasing the overall success rate to 89.5 % (n = 17). Four patients gained one line of vision, and four patients lost one line of vision. The novel MP-TSCPC laser had a high rate of surgical success after a short follow-up period in patients with advanced glaucoma. Further long-term evaluation and comparison to the traditional transscleral cyclophotocoagulation are warranted.
authors.affiliation: Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, 19107, USA.
authors.forename: Sarah
authors.initials: S
authors.lastname: Kuchar
authors.affiliation: Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, 19107, USA.
authors.forename: Marlene R
authors.initials: MR
authors.lastname: Moster
authors.affiliation: Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, 19107, USA.
authors.forename: Courtney B
authors.initials: CB
authors.lastname: Reamer
authors.affiliation: Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, 19107, USA. MWaisbourd@willseye.org.
authors.forename: Michael
authors.initials: M
authors.lastname: Waisbourd
mesh_terms: D000368:Aged; D002924:Ciliary Body / Q000528:radiation effects; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000528:radiation effects; D017075:Laser Coagulation / Q000379:methods*; D054023:Lasers, Semiconductor / Q000627:therapeutic use; D008297:Male; D012590:Sclera; D016896:Treatment Outcome; D014792:Visual Acuity / Q000528:radiation effects
keywords: Glaucoma; MP3 laser surgery; Micropulse diode laser; Transscleral cyclophotocoagulation