title: ASSOCIATION AMONG HISTOLOGICAL FINDINGS SUGGESTIVE OF PAPILLOMA VIRUS ON HEMORRHOIDECTOMY SPECIMENS.
abstract: BACKGROUND
  Many researchers studied human Papillomavirus infection in the anal area supposing it represents a risk factor for precursor lesions of anal cancer.
  
  
  OBJECTIVE
  To study the association between histological findings suggestive of injury by the virus in hemorrhoidectomy specimens.
  
  
  METHODS
  Prevalence study was carried out based on histopathological analysis of hemorrhoidectomy specimens to find viral cytopathic effects. These findings were compared with anal condyloma acuminata that had no relationship with hemorrhoidectomy for microscopic comparison.
  
  
  RESULTS
  Of the 91 hemorroidectomies analyzed, eight had findings suggestive of viral cytopathic effects, with the presence of irregular acanthosis in 63%, koilocytes in 50% and other indirect viral cytopathic effects, such as hyperkeratosis (38%), parakeratosis (25% ) and papillomatosis (13%).
  
  
  CONCLUSIONS
  This study was unable to conclude that there is an association between these two pathologic entities.
authors.affiliation: Getúlio Vargas University Hospital, Federal University of Amazonas, Manaus, AM, Brazil.
authors.forename: Soraya Souto
authors.initials: SS
authors.lastname: da Silva
authors.affiliation: Getúlio Vargas University Hospital, Federal University of Amazonas, Manaus, AM, Brazil.
authors.forename: Gerson Suguiyama
authors.initials: GS
authors.lastname: Nakajima
authors.affiliation: Getúlio Vargas University Hospital, Federal University of Amazonas, Manaus, AM, Brazil.
authors.forename: Ricardo Alexandre
authors.initials: RA
authors.lastname: Guimarães
authors.affiliation: Getúlio Vargas University Hospital, Federal University of Amazonas, Manaus, AM, Brazil.
authors.forename: Flávia da Costa
authors.initials: Fda C
authors.lastname: Mourão
mesh_terms: D061865:Hemorrhoidectomy; D006484:Hemorrhoids / Q000473:pathology / Q000601:surgery* / Q000821:virology*; D006801:Humans; D027383:Papillomaviridae / Q000302:isolation & purification*