title: Sleep Disturbances in Neurodevelopmental Disorders.
abstract: Sleep disturbances are extremely prevalent in children with neurodevelopmental disorders compared to typically developing children. The diagnostic criteria for many neurodevelopmental disorders include sleep disturbances. Sleep disturbance in this population is often multifactorial and caused by the interplay of genetic, neurobiological and environmental overlap. These disturbances often present either as insomnia or hypersomnia. Different sleep disorders present with these complaints and based on the clinical history and findings from diagnostic tests, an appropriate diagnosis can be made. This review aims to provide an overview of causes, diagnosis, and treatment of sleep disturbances in neurodevelopmental disorders that present primarily with symptoms of hypersomnia and/or insomnia.
authors.affiliation: Sleep Division, Department of Neurology A-0118 MCN, Vanderbilt University Medical Center, 1161 21st Ave. South, Nashville, TN, 37232, USA. althea.a.robinson@vanderbilt.edu.
authors.forename: Althea
authors.initials: A
authors.lastname: Robinson-Shelton
authors.affiliation: Sleep Division, Department of Neurology A-0118 MCN, Vanderbilt University Medical Center, 1161 21st Ave. South, Nashville, TN, 37232, USA. beth.a.malow@vanderbilt.edu.
authors.forename: Beth A
authors.initials: BA
authors.lastname: Malow
mesh_terms: D002648:Child; D019468:Disease Management; D006801:Humans; D065886:Neurodevelopmental Disorders / Q000145:classification / Q000150:complications / Q000175:diagnosis / Q000523:psychology; D017286:Polysomnography / Q000379:methods; D011580:Psychological Techniques; D012893:Sleep Wake Disorders / Q000209:etiology / Q000523:psychology / Q000628:therapy
keywords: Angelman syndrome; Autism spectrum disorder; Down syndrome; Neurodevelopmental disorders; Prader Willi syndrome; Sleep disturbances; Trisomy 21