title: Experimental Study of Micro-Scale Taylor Vortices Within a Co-Axial Mixed-Flow Blood Pump.
abstract: Taylor vortices in a miniature mixed-flow rotodynamic blood pump were investigated using micro-scale particle image velocimetry (μ-PIV) and a tracer particle visualization technique. The pump featured a cylindrical rotor (14.9 mm diameter) within a cylindrical bore, having a radial clearance of 500 μm and operated at rotational speeds varying from 1000 to 12 000 rpm. Corresponding Taylor numbers were 700-101 800, respectively. The critical Taylor number was observed to be highly dependent on the ratio of axial to circumferential velocity, increasing from 1200 to 18 000 corresponding to Rossby numbers from 0 to 0.175. This demonstrated a dramatic stabilizing effect of the axial flow. The size of Taylor vortices was also found to be inversely related to Rossby number. It is concluded that Taylor vortices can enhance the mixing in the annular gap and decrease the dwell time of blood cells in the high-shear-rate region, which has the potential to decrease hemolysis and platelet activation within the blood pump.
authors.affiliation: Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
authors.forename: Fangjun
authors.initials: F
authors.lastname: Shu
authors.affiliation: Department of Mechanical and Aerospace Engineering, New Mexico State University, Las Cruces, NM, USA.
authors.forename: Ruijun
authors.initials: R
authors.lastname: Tian
authors.affiliation: Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.|ARTORG Center for Biomedical Research, University of Bern, Bern, Switzerland.
authors.forename: Stijn
authors.initials: S
authors.lastname: Vandenberghe
authors.affiliation: Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
authors.forename: James F
authors.initials: JF
authors.lastname: Antaki
mesh_terms: D004867:Equipment Design; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006461:Hemolysis; D057446:Hydrodynamics; D044085:Microfluidics; D008955:Models, Cardiovascular; D015539:Platelet Activation; D012212:Rheology
keywords: Blood pump; Hemolysis; Micro particle image velocimetry; Taylor vortices