title: Anti-Biofouling Effect of PEG-Grafted Block Copolymer Synthesized by RAFT Polymerization.
abstract: Poly(glycidyl methadrylate-block-styrene) (PGMA-b-PS), a block copolymer consisting of glycidyl methacrylate and styrene, was synthesized via reversible addition-fragmentation chain transfer living polymerization. The synthesized PGMA-b-PS was then grafted with low-molecular-weight polyethylene glycol (PEG) via epoxy ring opening to give PGMA-g-PEG-b-PS, which was evaluated as an anti-biofouling coating material. As a preliminary test for the anti-biofouling effect, a protein adsorption experiment was performed on the synthesized block copolymer surface. The block copolymers were spin-coated onto silicon wafers, and protein adsorption experiments were carried out using fluorescein isothiocyanate conjugate-labeled bovine serum albumin. The fluorescence intensity of the protein adsorbed on the block copolymer surface was compared with that of a polystyrene film as a reference. The synthesized PGMA-g-PEG-b-PS film showed much lower fluorescence intensity than that of the PS film.
authors.forename: Seon-Mi
authors.initials: SM
authors.lastname: Kim
authors.forename: Sang Suk
authors.initials: SS
authors.lastname: Han
authors.forename: A Young
authors.initials: AY
authors.lastname: Kim
authors.forename: Beom-Jin
authors.initials: BJ
authors.lastname: Choi
authors.forename: Hyun-Jong
authors.initials: HJ
authors.lastname: Paik
authors.forename: Inwon
authors.initials: I
authors.lastname: Lee
authors.forename: Hyun
authors.initials: H
authors.lastname: Park
authors.forename: Ho Hwan
authors.initials: HH
authors.lastname: Chun
authors.forename: Youngjin
authors.initials: Y
authors.lastname: Cho
authors.forename: Do-Hoon
authors.initials: DH
authors.lastname: Hwang
mesh_terms: D000327:Adsorption; D000818:Animals; D057219:Biofouling / Q000517:prevention & control*; D002417:Cattle; D004852:Epoxy Compounds / Q000737:chemistry*; D008689:Methacrylates / Q000737:chemistry*; D011409:Propylene Glycols / Q000138:chemical synthesis / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D020058:Styrene / Q000737:chemistry*
chemical_list: D004852:Epoxy Compounds; D008689:Methacrylates; D011409:Propylene Glycols; D012710:Serum Albumin, Bovine; D020058:Styrene; C007870:glycidyl methacrylate