title: Cutaneous metastasis of unknown primary presenting as massive and invasive abdominal lesion: an elective approach with electrochemotherapy.
abstract: We describe herein what is to our knowledge the first reported case of an invasive cutaneous metastasis with unknown primary, electively treated solely with electrochemotherapy. We describe a female patient with a large, invasive and painful lesion in her hypogastric region, extending up to the pubic area. The cutaneous biopsy and instrumental and laboratory analyses, all failed to reveal the primary site. A final diagnosis of cutaneous metastasis with unknown primary was made and treatment was performed with electrochemotherapy. Our case highlights the importance of interdisciplinary choices in clinical practice to cope with the lack of a primary site and to improve quality of life, since no standardized therapy exists for these classes of patients.
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Lido
authors.affiliation: Università degli Studi di Roma "La Sapienza", Rome, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Paolino
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Feliziani
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Letizia
authors.initials: L
authors.lastname: Santurro
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Montuori
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Flavio de
authors.initials: Fd
authors.lastname: Sanctis
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Piero
authors.initials: P
authors.lastname: Rossi
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Petrella
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Ricciardi
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Fusano
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Orlandi
authors.initials: O
authors.lastname: Augusto
authors.affiliation: Università degli Studi di Roma Tor Vergata, Rome, Italy.
authors.forename: Patrizio
authors.initials: P
authors.lastname: Polisca
mesh_terms: D000008:Abdominal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D001706:Biopsy; D053672:Electrochemotherapy / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009382:Neoplasms, Unknown Primary / Q000188:drug therapy* / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D016896:Treatment Outcome