title: Plasmakinetic enucleation of prostate versus 160-W laser photoselective vaporization for the treatment of benign prostatic hyperplasia.
abstract: To evaluate the safety and efficacy of plasmakinetic enucleation of the prostate (PKEP) for the treatment of symptomatic benign prostatic hyperplasia (BPH) compared with 160-W lithium triboride laser photoselective vaporization of the prostate (PVP). From February 2011 to July 2012, a prospective nonrandomized study was performed. One-hundred one patients underwent PKEP, and 110 underwent PVP. No severe intraoperative complications were recorded, and none of the patients in either group required a blood transfusion. Shorter catheterization time (38.14 ± 23.64 h vs 72.54 ± 28.38 h, P< 0.001) and hospitalization (2.32 ± 1.25 days vs 4.07 ± 1.23 days, P< 0.001) were recorded in the PVP group. At 12-month postoperatively, the PKEP group had a maintained and statistically improvement in International Prostate Symptom Score (IPSS) (4.07 ± 2.07 vs 5.00 ± 2.10; P< 0.001), quality of life (QoL) (1.08 ± 0.72 vs 1.35 ± 0.72; P= 0.007), maximal urinary flow rate (Qmax) (24.75 ± 5.87 ml s-1 vs 22.03 ± 5.04 ml s-1 ; P< 0.001), postvoid residual urine volume (PVR) (14.29 ± 6.97 ml vs 17.00 ± 6.11 ml; P= 0.001), and prostate-specific antigen (PSA) value (0.78 ± 0.57 ng ml-1 vs 1.27 ± 1.07 ng ml-1 ; P< 0.001). Both PKEP and PVP relieve low urinary tract symptoms (LUTS) due to BPH with low complication rates. PKEP can completely remove prostatic adenoma while the total amount of tissue removed by PVP is less than that can be removed by PKEP. Based on our study of the follow-up, PKEP provides better postoperative outcomes than PVP.
authors.affiliation: Department of Urology, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, P.R. China.
authors.forename: Si-Jun
authors.initials: SJ
authors.lastname: Wang
authors.affiliation: Department of Concerning Foreign Affairs, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, P.R. China.
authors.forename: Xiao-Nan
authors.initials: XN
authors.lastname: Mu
authors.affiliation: Department of Minimally Invasive Urology, Provincial Hospital Affiliated to Shandong University, Jinan 250021, P.R. China.
authors.forename: Ji
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Minimally Invasive Urology, Provincial Hospital Affiliated to Shandong University, Jinan 250021, P.R. China.
authors.forename: Xun-Bo
authors.initials: XB
authors.lastname: Jin
authors.affiliation: Department of Urology, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, P.R. China.
authors.forename: Shi-Bao
authors.initials: SB
authors.lastname: Zhang
authors.affiliation: Department of Urology, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, P.R. China.
authors.forename: Long-Yang
authors.initials: LY
authors.lastname: Zhang
mesh_terms: D000368:Aged; D004598:Electrosurgery / Q000379:methods*; D006801:Humans; D007610:Kallikreins / Q000097:blood; D053685:Laser Therapy / Q000379:methods*; D007902:Length of Stay; D059411:Lower Urinary Tract Symptoms / Q000209:etiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000097:blood / Q000150:complications / Q000601:surgery*; D011788:Quality of Life; D020728:Transurethral Resection of Prostate / Q000379:methods*; D016896:Treatment Outcome
chemical_list: C549870:KLK3 protein, human; D007610:Kallikreins; D017430:Prostate-Specific Antigen