title: Primary cardiac malignant fibrous histiocytoma with vulvar metastases: A case report.
abstract: Malignant fibrous histiocytoma (MFH) occurring in the heart is rare. To the best of our knowledge, the current study was the first to report a case of left atrial MFH metastasizing to the vulva. A 37-year-old female presenting with a history of exertional dyspnea underwent echocardiography, which revealed a mass in the left atrium, with a short-wide stalk attached to the posterior wall, extending into the pericardium. Furthermore, the mass resulted in severe mitral stenosis during diastole. The tumor was excised together with a section of the left atrial wall. The initial diagnosis was a left atrial myxoma. However, post-operative frozen section histopathology results indicated a diagnosis of MFH. Following surgery, the patient received chemotherapy, however, vulvar metastases and left pleural effusions were identified after 1 month. Following surgical excision of the vulvar tumor and left thoracentesis, the patient began adjuvant chemotherapy. However, the patient succumbed due to local recurrence 6 months later.
authors.affiliation: Department of Ultrasound, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Sun
authors.affiliation: Department of Ultrasound, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
authors.forename: Ruihua
authors.initials: R
authors.lastname: Liu
authors.affiliation: Department of Ultrasound, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Ultrasound, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
authors.forename: Minghui
authors.initials: M
authors.lastname: Sun
authors.affiliation: Department of Ultrasound, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
authors.forename: Lihong
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Ultrasound, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Ultrasound, Yantai Yuhuangding Hospital, Yantai, Shandong 264000, P.R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
keywords: cardiac sarcoma; echocardiography; malignant fibrous histiocytoma of the heart; vulvar sarcoma