title: Effects of Humidity Variation on the Hantavirus Infection and Hemorrhagic Fever with Renal Syndrome Occurrence in Subtropical China.
abstract: Infection rates of rodents have a significant influence on the transmission of hemorrhagic fever with renal syndrome (HFRS). In this study, four cities and two counties with high HFRS incidence in eastern Hunan Province in China were studied, and surveillance data of rodents, as well as HFRS cases and related environmental variables from 2007 to 2010, were collected. Results indicate that the distribution and infection rates of rodents are closely associated with environmental conditions. Hantavirus infections in rodents were positively correlated with temperature vegetation dryness index and negatively correlated with elevation. The predictive risk maps based on multivariate regression model revealed that the annual variation of infection risks is small, whereas monthly variation is large and corresponded well to the seasonal variation of human HFRS incidence. The identification of risk factors and risk prediction provides decision support for rodent surveillance and the prevention and control of HFRS.
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China xiaohong.hnnu@gmail.com tianhuaiyu@gmail.com.
authors.forename: Hong
authors.initials: H
authors.lastname: Xiao
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China.
authors.forename: Ru
authors.initials: R
authors.lastname: Huang
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China.
authors.forename: Li-Dong
authors.initials: LD
authors.lastname: Gao
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China.
authors.forename: Cun-Rui
authors.initials: CR
authors.lastname: Huang
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China.
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Lin
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China.
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China.
authors.forename: Hai-Ning
authors.initials: HN
authors.lastname: Liu
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China.
authors.forename: Shi-Lu
authors.initials: SL
authors.lastname: Tong
authors.affiliation: College of Resources and Environment Science, Hunan Normal University, Changsha, China; Hunan Provincial Center for Disease Control and Prevention, Changsha, China; School of Public Health, Sun Yat-Sen University, Guangzhou, China; Weizikeng Center for Disease Control and Prevention, Beijing, China; School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia; State Key Laboratory of Remote Sensing Science, College of Global Change and Earth System Science, Beijing Normal University, Beijing, China xiaohong.hnnu@gmail.com tianhuaiyu@gmail.com.
authors.forename: Huai-Yu
authors.initials: HY
authors.lastname: Tian
mesh_terms: D000818:Animals; D002681:China / Q000453:epidemiology; D006476:Orthohantavirus; D018778:Hantavirus Infections / Q000453:epidemiology*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology*; D006801:Humans; D006813:Humidity; D012307:Risk Factors; D012377:Rodentia; D012621:Seasons; D013997:Time Factors