title: Cost-utility Analysis of Supported Self-management with Motiva-tional Interviewing for Patients with Psoriasis.
abstract: There are few studies evaluating the cost-effectiveness of self-management interventions for patients with psoriasis. Motivational interviewing (MI) as a telephone follow-up after climate-heliotherapy was effective on several clinical parameters, but its cost-effectiveness is unknown. A cost-utility analysis was conducted alongside a randomized controlled trial (RCT) comparing MI with usual care. A total of 169 Norwegian patients were included. A within-trial analysis compared the costs and quality-adjusted life years (QALYs). Utilities were measured with the 15D instrument, supplemented with Dermatological Life Quality Index (DLQI). A time-integrated summary score defined the clinical effects. QALYs were adjusted for baseline differences. MI provided equivalent quality of life and utility (15D: -0.0022 QALYs (95% Cl -0.02, 0.01), p = 0.77, and DLQI: -0.62 QALYs (95%CI -0.65, 0.41), p = 0.24, at lower costs €-1103 (-2293, 87), p = 0.058, compared with treatment-as-usual. The MI intervention was thus cost-effective. This result was more evident when using the DLQI as outcome measure compared with 15D.
authors.affiliation: Department of Health Sciences, Institute of Health and Society, Medical Faculty, University of Oslo, Oslo, Norway. m.h.larsen@medisin.uio.no.
authors.forename: Marie H
authors.initials: MH
authors.lastname: Larsen
authors.forename: Astrid K
authors.initials: AK
authors.lastname: Wahl
authors.forename: Anne-Lene
authors.initials: AL
authors.lastname: Krogstad
authors.forename: Eline
authors.initials: E
authors.lastname: Aas
mesh_terms: D003362:Cost-Benefit Analysis; D005260:Female; D006370:Heliotherapy / Q000191:economics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D062405:Motivational Interviewing / Q000191:economics*; D009664:Norway; D011565:Psoriasis / Q000628:therapy*; D011788:Quality of Life; D019057:Quality-Adjusted Life Years; D012648:Self Care / Q000191:economics*; D016896:Treatment Outcome