title: Infiltration with lidocaine and adrenaline instead of normal saline does not improve the septoplasty procedure.
abstract: The aim of this study was to determine whether infiltration of local anesthetics with adrenaline improved septoplasty procedure when compared to normal saline. Eight-two patients undergoing septoplasty were randomized into two groups. In group 1, septal mucoperichondrium was infiltrated with lidocaine with adrenaline, and normal saline was used in group 2. Presence of intra-operative septal mucosal injuries, the amount of bleeding, arterial blood pressure, operation time as well as the quality of the surgical field and the convenience of finding the correct surgical plane as determined by the surgeon using a 5-point scale were compared between two groups. There were no significant differences for the amount of blood loss, mean arterial pressure, operation time, or scores for convenience of finding the correct surgical plane between the two groups. There was no significant difference for intra-operative simple (P = 0.631) and total (simple+severe) (P = 0.649) septal mucoperichondrial injuries between groups 1 and 2, either. However, severe mucoperichondrial injury rate was higher in the patients infiltrated with lidocaine and adrenaline (P = 0.026), and the quality of the surgical field was worse in the patients injected with normal saline (P = 0.0179). Infiltration of septal mucoperichondrium with lidocaine and adrenaline instead of normal saline was not advantageous in terms of objective parameters tested, including bleeding amount and duration of surgery as well as the of the total mucosal injury rate in septoplasty procedure.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Ankara Numune Education and Research Hospital, Ankara, 06530, Turkey. vgungor@outlook.com.
authors.forename: Volkan
authors.initials: V
authors.lastname: Gungor
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Ankara Numune Education and Research Hospital, Ankara, 06530, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Baklaci
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Ankara Numune Education and Research Hospital, Ankara, 06530, Turkey.
authors.forename: Rauf Oguzhan
authors.initials: RO
authors.lastname: Kum
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Ankara Numune Education and Research Hospital, Ankara, 06530, Turkey.
authors.forename: Yavuz Fuat
authors.initials: YF
authors.lastname: Yilmaz
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Ankara Numune Education and Research Hospital, Ankara, 06530, Turkey.
authors.forename: Muge
authors.initials: M
authors.lastname: Ozcan
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Ankara Numune Education and Research Hospital, Ankara, 06530, Turkey.
authors.forename: Adnan
authors.initials: A
authors.lastname: Unal
mesh_terms: D000293:Adolescent; D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001794:Blood Pressure / Q000187:drug effects*; D004837:Epinephrine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D061270:Nasal Septal Perforation / Q000209:etiology; D009300:Nasal Septum / Q000293:injuries / Q000601:surgery*; D061646:Operative Time; D012225:Rhinoplasty; D012965:Sodium Chloride / Q000008:administration & dosage*; D018709:Statistics, Nonparametric; D014662:Vasoconstrictor Agents / Q000008:administration & dosage*
chemical_list: D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D012965:Sodium Chloride; D008012:Lidocaine; D004837:Epinephrine
keywords: Adrenaline; Local anesthetics; Nasal septum