title: LymPHOS 2.0: an update of a phosphosite database of primary human T cells.
abstract: LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes. Current release 2.0 contains 15 566 phosphorylation sites from 8273 unique phosphopeptides and 4937 proteins, which correspond to a 45-fold increase over the original database description. It now includes quantitative data on phosphorylation changes after time-dependent treatment with activators of the TCR-mediated signal transduction pathway. Sequence data quality has also been improved with the use of multiple search engines for database searching. LymPHOS can be publicly accessed at http://www.lymphos.org. Database URL: http://www.lymphos.org.
authors.affiliation: CSIC/UAB Proteomics Laboratory, Instituto De Investigaciones Biomédicas De Barcelona-Consejo Superior De Investigaciones Científicas (IIBB-CSIC/IDIBAPS), Rosellón 161 6a Planta, Barcelona E-08036, Spain.
authors.forename: Tien Dung
authors.initials: TD
authors.lastname: Nguyen
authors.affiliation: CSIC/UAB Proteomics Laboratory, Instituto De Investigaciones Biomédicas De Barcelona-Consejo Superior De Investigaciones Científicas (IIBB-CSIC/IDIBAPS), Rosellón 161 6a Planta, Barcelona E-08036, Spain.
authors.forename: Oriol
authors.initials: O
authors.lastname: Vidal-Cortes
authors.affiliation: CSIC/UAB Proteomics Laboratory, Instituto De Investigaciones Biomédicas De Barcelona-Consejo Superior De Investigaciones Científicas (IIBB-CSIC/IDIBAPS), Rosellón 161 6a Planta, Barcelona E-08036, Spain.
authors.forename: Oscar
authors.initials: O
authors.lastname: Gallardo
authors.affiliation: CSIC/UAB Proteomics Laboratory, Instituto De Investigaciones Biomédicas De Barcelona-Consejo Superior De Investigaciones Científicas (IIBB-CSIC/IDIBAPS), Rosellón 161 6a Planta, Barcelona E-08036, Spain.
authors.forename: Joaquin
authors.initials: J
authors.lastname: Abian
authors.affiliation: CSIC/UAB Proteomics Laboratory, Instituto De Investigaciones Biomédicas De Barcelona-Consejo Superior De Investigaciones Científicas (IIBB-CSIC/IDIBAPS), Rosellón 161 6a Planta, Barcelona E-08036, Spain montserrat.carrascal.csic@uab.cat.
authors.forename: Montserrat
authors.initials: M
authors.lastname: Carrascal
mesh_terms: D000595:Amino Acid Sequence; D002478:Cells, Cultured; D019992:Databases as Topic; D063990:Gene Ontology; D006801:Humans; D020935:MAP Kinase Signaling System; D008969:Molecular Sequence Data; D010748:Phosphopeptides / Q000737:chemistry / Q000378:metabolism*; D020543:Proteome / Q000378:metabolism; D013601:T-Lymphocytes / Q000378:metabolism*
chemical_list: D010748:Phosphopeptides; D020543:Proteome