title: A DNA tetrahedron-based molecular beacon for tumor-related mRNA detection in living cells.
abstract: Due to its low cytotoxicity, high resistance to enzymatic degradation, and cellular permeability, a DNA tetrahedron-based molecular beacon (DTMB) is designed for tumor-related TK1 mRNA detection in living cells, where the target sequence can induce the tetrahedron from contraction to extension, resulting in fluorescence restoration.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: Nuli
authors.initials: N
authors.lastname: Xie
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: Jin
authors.initials: J
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: Xiaohai
authors.initials: X
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: Yanjing
authors.initials: Y
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: Ke
authors.initials: K
authors.lastname: Quan
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: He
authors.initials: H
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: Le
authors.initials: L
authors.lastname: Ying
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: Min
authors.initials: M
authors.lastname: Ou
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China. jinhuang@hnu.edu.cn kmwang@hnu.edu.cn.
authors.forename: Kemin
authors.initials: K
authors.lastname: Wang
mesh_terms: D004247:DNA / Q000737:chemistry*; D006801:Humans; D012333:RNA, Messenger / Q000032:analysis*; D012334:RNA, Neoplasm / Q000032:analysis*
chemical_list: D012333:RNA, Messenger; D012334:RNA, Neoplasm; D004247:DNA