title: Development of health diagnostics based on personalized medical models.
abstract: Due to rapid evolution of new technologies the concept of personalized medicine has evolved. Components include molecular biology, proteomics, metabolomic analysis, genetic testing, and molecular medicine for diagnostics. In addition to diagnostics these methods can be used to determine individual susceptibility to diseases and conditions. In conjunction with new diagnostic methods, new therapies can be tailored to the individual. These new technologies present a challenge in terms of the expansion of the medical record as well as the development of new methods for creating disease profiles. This article focuses on a computer-aided support for personalized medicine. Specific approaches are explored that permit automated data analysis for prognosis and treatment based on analysis methods for numeric and pictorial data. Although personalized medicine based on the genome of the patient are occasionally performed, because of the large amount of data new methods are needed to form general disease models as well as specific profiles of the individual patient.
authors.forename: D L
authors.initials: DL
authors.lastname: Hudson
authors.forename: M E
authors.initials: ME
authors.lastname: Cohen
authors.forename: S E
authors.initials: SE
authors.lastname: Hudson
mesh_terms: D006801:Humans; D057285:Precision Medicine; D011379:Prognosis; D040901:Proteomics