title: Variance Component Quantitative Trait Locus Analysis for Body Weight Traits in Purebred Korean Native Chicken.
abstract: Quantitative trait locus (QTL) is a particular region of the genome containing one or more genes associated with economically important quantitative traits. This study was conducted to identify QTL regions for body weight and growth traits in purebred Korean native chicken (KNC). F1 samples (n = 595) were genotyped using 127 microsatellite markers and 8 single nucleotide polymorphisms that covered 2,616.1 centi Morgan (cM) of map length for 26 autosomal linkage groups. Body weight traits were measured every 2 weeks from hatch to 20 weeks of age. Weight of half carcass was also collected together with growth rate. A multipoint variance component linkage approach was used to identify QTLs for the body weight traits. Two significant QTLs for growth were identified on chicken chromosome 3 (GGA3) for growth 16 to18 weeks (logarithm of the odds [LOD] = 3.24, Nominal p value = 0.0001) and GGA4 for growth 6 to 8 weeks (LOD = 2.88, Nominal p value = 0.0003). Additionally, one significant QTL and three suggestive QTLs were detected for body weight traits in KNC; significant QTL for body weight at 4 weeks (LOD = 2.52, nominal p value = 0.0007) and suggestive QTL for 8 weeks (LOD = 1.96, Nominal p value = 0.0027) were detected on GGA4; QTLs were also detected for two different body weight traits: body weight at 16 weeks on GGA3 and body weight at 18 weeks on GGA19. Additionally, two suggestive QTLs for carcass weight were detected at 0 and 70 cM on GGA19. In conclusion, the current study identified several significant and suggestive QTLs that affect growth related traits in a unique resource pedigree in purebred KNC. This information will contribute to improving the body weight traits in native chicken breeds, especially for the Asian native chicken breeds.
authors.affiliation: Division of Animal and Dairy Science, Chungnam National University, Daejeon 305-764 Korea ; Department of Animal Science, Faculty of Agriculture, Sebelas Maret University, Surakarta 57126, Indonesia .
authors.forename: Muhammad
authors.initials: M
authors.lastname: Cahyadi
authors.affiliation: Division of Animal and Dairy Science, Chungnam National University, Daejeon 305-764 Korea.
authors.forename: Hee-Bok
authors.initials: HB
authors.lastname: Park
authors.affiliation: Division of Animal and Dairy Science, Chungnam National University, Daejeon 305-764 Korea.
authors.forename: Dong-Won
authors.initials: DW
authors.lastname: Seo
authors.affiliation: Division of Animal and Dairy Science, Chungnam National University, Daejeon 305-764 Korea.
authors.forename: Shil
authors.initials: S
authors.lastname: Jin
authors.affiliation: Division of Animal and Dairy Science, Chungnam National University, Daejeon 305-764 Korea.
authors.forename: Nuri
authors.initials: N
authors.lastname: Choi
authors.affiliation: Poultry Science Division, National Institute of Animal Science, RDA, Cheonan 331-801, Korea .
authors.forename: Kang-Nyeong
authors.initials: KN
authors.lastname: Heo
authors.affiliation: Poultry Science Division, National Institute of Animal Science, RDA, Cheonan 331-801, Korea .
authors.forename: Bo-Seok
authors.initials: BS
authors.lastname: Kang
authors.affiliation: Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Science, Seoul National University, Seoul 151-921, Korea .
authors.forename: Cheorun
authors.initials: C
authors.lastname: Jo
authors.affiliation: Division of Animal and Dairy Science, Chungnam National University, Daejeon 305-764 Korea.
authors.forename: Jun-Heon
authors.initials: JH
authors.lastname: Lee
keywords: Body Weight; Growth; Korean Native Chicken; Purebred; Quantitative Trait Locus