title: [In Situ Polymerization and Characterization of Hydroxyapatite/polyurethane Implanted Material].
abstract: In order to improve the interfacial bonding strength of hydroxyapatite/polyurethane implanted material and dispersion of hydroxyapatite in the polyurethane matrix, we in the present study synthesized nano-hydroxyapatite/polyurethane composites by in situ polymerization. We then characterized and analyzed the fracture morphology, thermal stability, glass transition temperature and mechanical properties. We seeded MG63 cells on composites to evaluate the cytocompatibility of the composites. In situ polymerization could improve the interfacial bonding strength, ameliorate dispersion of hydroxyapatite in the properties of the composites. After adding 20 wt% hydroxyapatite into the polyurethane, the thermal stability was improved and the glass transition temperatures were increased. The tensile strength and maximum elongation were 6.83 MPa and 861.17%, respectively. Compared with those of pure polyurethane the tensile strength and maximum elongation increased by 236.45% and 143.30%, respectively. The composites were helpful for cell adhesion and proliferation in cultivation.
authors.forename: Muqing
authors.initials: M
authors.lastname: Gu
authors.forename: Fengjuan
authors.initials: F
authors.lastname: Xiao
authors.forename: Ye
authors.initials: Y
authors.lastname: Liang
authors.forename: Lin
authors.initials: L
authors.lastname: Yue
authors.forename: Song
authors.initials: S
authors.lastname: Li
authors.forename: Lanlan
authors.initials: L
authors.lastname: Li
authors.forename: Feifei
authors.initials: F
authors.lastname: Feng
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D002448:Cell Adhesion; D002460:Cell Line; D017886:Durapatite / Q000737:chemistry*; D006801:Humans; D058105:Polymerization; D011140:Polyurethanes; D013718:Tensile Strength; D044366:Transition Temperature
chemical_list: D001672:Biocompatible Materials; D011140:Polyurethanes; D017886:Durapatite