title: Theory and application of arterial tissue in-host remodelling.
abstract: A central therapeutic goal in many applications of modern Biomedicine is the reconstruction of the diseased arterial sections via robust and viable tissue equivalents. In-host remodelling is an emerging technology that exploits the remodelling ability of the host to regenerate tissue. We develop a general theoretical framework of growth and remodeling of arterial tissue starting from a synthetic, degradable, acellularized graft and we demonstrate the potential of mechanistic models to guide the development and assisting in the design of arterial tissue engineered constructs.
authors.forename: A
authors.initials: A
authors.lastname: Valentin
authors.forename: D
authors.initials: D
authors.lastname: Notaro
authors.forename: P
authors.initials: P
authors.lastname: Zunino
authors.forename: R
authors.initials: R
authors.lastname: Allen
authors.forename: D
authors.initials: D
authors.lastname: Ambrosi
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: A M
authors.initials: AM
authors.lastname: Robertson
mesh_terms: D001158:Arteries / Q000502:physiology*; D001696:Biomechanical Phenomena; D006801:Humans; D008955:Models, Cardiovascular; D012038:Regeneration / Q000502:physiology; D023822:Tissue Engineering / Q000379:methods*