title: Individualized real-time clinical decision support to monitor cardiac loading during venoarterial ECMO.
abstract: Veno-arterial extracoporeal membrane oxygenation (VA ECMO) is increasingly used for acute and refractory cardiogenic shock. Yet, in clinical practice, monitoring of cardiac loading conditions during VA ECMO can be cumbersome. To this end, we illustrate the validity and clinical applicability of a real-time cardiovascular computer simulation, which allows to integrate hemodynamics, cardiac dimensions and the corresponding degree of VA ECMO support and ventricular loading in individual patients over time.
authors.affiliation: School of Technology and Health, KTH Royal Institute of Technology, Alfred Nobels Allé 10, Huddinge, 141 52, Stockholm, Sweden. michael.broome@karolinska.se.|ECMO Centre, Astrid Lindgren Children's Hospital, Karolinska University Hospital, 171 76, Stockholm, Sweden. michael.broome@karolinska.se.|Anesthesiology and Intensive Care Medicine, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77, Stockholm, Sweden. michael.broome@karolinska.se.
authors.forename: Michael
authors.initials: M
authors.lastname: Broomé
authors.affiliation: Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, The Netherlands. D.W.Donker@umcutrecht.nl.
authors.forename: Dirk W
authors.initials: DW
authors.lastname: Donker
mesh_terms: D003198:Computer Simulation; D003199:Computer Systems; D020000:Decision Support Systems, Clinical; D003971:Diastole; D004562:Electrocardiography; D015199:Extracorporeal Membrane Oxygenation; D006321:Heart / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D008991:Monitoring, Physiologic; D057285:Precision Medicine