title: Ir(III)-Catalyzed Synthesis of Isoquinoline N-Oxides from Aryloxime and α-Diazocarbonyl Compounds.
abstract: An efficient Ir(III)-catalyzed C-H activation and annulations of aryloxime with α-diazocarbonyl compounds has been developed for the synthesis of substituted isoquinoline N-oxides. The reaction proceeds under mild atmospheric conditions, without any external oxidants and releases N2 and H2O as the byproducts. In addition, synthetic applications of the N-oxide products have been established by performing further functionalization. An interesting dimeric iridacyclic complex allied through a bis-silver carboxylate bridge has been isolated that efficiently catalyzed the reaction.
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory , Dr. Homi Bhaba Road, Pune, India 411008.
authors.forename: Ravindra S
authors.initials: RS
authors.lastname: Phatake
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory , Dr. Homi Bhaba Road, Pune, India 411008.|Natural Product Chemistry Division, CSIR-North East Institute of Science and Technology , Jorhat, India 785006.
authors.forename: Pitambar
authors.initials: P
authors.lastname: Patel
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory , Dr. Homi Bhaba Road, Pune, India 411008.
authors.forename: Chepuri V
authors.initials: CV
authors.lastname: Ramana