title: Upright Magnetic Resonance Imaging Tasks in the Knee Osteoarthritis Population: Relationships Between Knee Flexion Angle, Self-Reported Pain, and Performance.
abstract: To characterize the ability of patients with symptomatic knee osteoarthritis (OA) to perform a weight-bearing activity compatible with upright magnetic resonance imaging (MRI) scanning and how this ability is affected by knee pain symptoms and flexion angles.
  
  
  
  Cross-sectional observational study assessing effects of knee flexion angle, pain level, and study sequence on accuracy and duration of performing a task used in weight-bearing MRI evaluation. Visual feedback of knee position from an MRI compatible sensor was provided. Pain levels were self-reported on a standardized scale.
  
  
  
  Simulated MRI setup in a research laboratory.
  
  
  
  Convenience sample of individuals (N=14; 9 women, 5 men; mean, 69±14y) with symptomatic knee OA.
  
  
  
  Not applicable.
  
  
  
  Averaged absolute and signed angle error from target knee flexion for each minute of trial and duration tolerance (the duration that subjects maintained position within a prescribed error threshold).
  
  
  
  Absolute targeting error increased at longer trial durations (P<.001). Duration tolerance decreased with increasing pain (mean ± SE, no pain: 3min 19s±11s; severe pain: 1min 49s±23s; P=.008). Study sequence affected duration tolerance (first knee: 3min 5s±9.1s; second knee: 2min 19s±9.7s; P=.015).
  
  
  
  The study provided evidence that weight-bearing MRI evaluations based on imaging protocols in the range of 2 to 3 minutes are compatible with patients reporting mild to moderate knee OA-related pain.
authors.affiliation: Human Performance and Engineering Research, Kessler Foundation, West Orange, NJ.
authors.forename: Venkata
authors.initials: V
authors.lastname: Gade
authors.affiliation: Human Performance and Engineering Research, Kessler Foundation, West Orange, NJ.
authors.forename: Jerome
authors.initials: J
authors.lastname: Allen
authors.affiliation: Kessler Institute for Rehabilitation, West Orange, NJ; Department of Physical Medicine and Rehabilitation, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ.
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Cole
authors.affiliation: Human Performance and Engineering Research, Kessler Foundation, West Orange, NJ; Department of Physical Medicine and Rehabilitation, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ. Electronic address: pbarrance@kesslerfoundation.org.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Barrance
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001696:Biomechanical Phenomena; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology* / Q000534:rehabilitation; D010146:Pain / Q000209:etiology / Q000503:physiopathology*; D026741:Physical Therapy Modalities; D016059:Range of Motion, Articular; D016474:Weight-Bearing / Q000502:physiology*
keywords: Knee; Magnetic resonance imaging; Osteoarthritis; Rehabilitation