title: [Study on the determinants of intrauterine growth restriction].
abstract: OBJECTIVE
  To investigate the intrauterine growth retardation (IUGR) and its determinants so as to provide evidence for maternal and child health care programs to be carried out.
  
  
  METHODS
  Fourteen townships were selected by cluster random sampling from 37 townships in Liuyang. A total of 6 105 pregnant women who had established their health care programs during April 2008 and March 2011, were recruited in this study. Records on pregnancy care manual and delivery were collected. 6 105 single live births were divided into two groups (IUGR group and control group). Those whose birth weight was below the 10th percentile for mean weight corrected for gestation age were grouped as IUGR group. Chi-square test and Multivariate logistic Regression method were used to estimate the determinants of IUGR.
  
  
  RESULTS
  A total of 6 105 women, pregnant with a singleton gestation were enrolled in the study: 528 of these pregnancies were complicated with IUGR (8.65%). Data from the multivariate logistic regression analysis showed that maternal age less than 25 (OR = 1.268), prim parity (OR = 1.706), BMI less than 18.5 kg/m² at first obstetrical examination (OR = 1.709), deficiency in weight gain during pregnancy (OR = 1.576) and pregnancy-induced hypertension syndrome (OR = 1.698) were related risk factors to intrauterine growth retardation.
  
  
  CONCLUSIONS
  Maternal age, prim parity, BMI, weight gain during pregnancy and pregnancy-induced hypertension syndrome were factors associated to the intrauterine growth retardation. Effective measures in reducing the intrauterine growth retardation should include factors as monitoring maternal weight and the change of weight during pregnancy in order to maintain the weight at normal ranges. Prevention and therapy for pregnancy-induced hypertension syndrome, should also be strengthened.
authors.affiliation: School of Public Heath, Central South University, Changsha 410008, China.
authors.forename: Yangfen
authors.initials: Y
authors.lastname: Li
authors.affiliation: Liuyang Maternal and Child Health Hospital.
authors.forename: Shujin
authors.initials: S
authors.lastname: Zhou
authors.affiliation: School of Public Heath, Central South University, Changsha 410008, China.
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Wang
authors.affiliation: School of Public Heath, Central South University, Changsha 410008, China; Xiangya Hospital, Central South University.
authors.forename: Yue
authors.initials: Y
authors.lastname: He
authors.affiliation: School of Public Heath, Central South University, Changsha 410008, China; Changsha Center for Disease Control and Prevention.
authors.forename: Lin
authors.initials: L
authors.lastname: Shen
authors.affiliation: School of Public Heath, Central South University, Changsha 410008, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Huang
authors.affiliation: School of Public Heath, Central South University, Changsha 410008, China.
authors.forename: Shiwu
authors.initials: S
authors.lastname: Wen
authors.affiliation: School of Public Heath, Central South University, Changsha 410008, China; Email: tanhz99@qq.com.
authors.forename: Hongzhuan
authors.initials: H
authors.lastname: Tan
mesh_terms: D001724:Birth Weight; D001835:Body Weight; D005260:Female; D005317:Fetal Growth Retardation; D006801:Humans; D046110:Hypertension, Pregnancy-Induced; D008423:Maternal Age; D010298:Parity; D011247:Pregnancy; D037841:Pregnant People; D012307:Risk Factors; D015430:Weight Gain