title: Synthesis and biophysical properties of (L)-aTNA based G-quadruplexes.
abstract: Novel G-quadruplex structures are constructed by acyclic (L)-threninol nucleic acid and their synthesis and biophysical properties are described. Pyrene excimer fluorescence and circular dichroism (CD) data revealed that four strands of aTNA are oriented in antiparallel direction.
authors.affiliation: Danish National Research Foundation Center for DNA Nanotechnology, iNANO and Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark. kvg@chem.au.dk.
authors.forename: Vipin
authors.initials: V
authors.lastname: Kumar
authors.affiliation: Danish National Research Foundation Center for DNA Nanotechnology, iNANO and Department of Chemistry, Aarhus University, 8000 Aarhus C, Denmark. kvg@chem.au.dk.
authors.forename: Kurt V
authors.initials: KV
authors.lastname: Gothelf
mesh_terms: D002942:Circular Dichroism; D005453:Fluorescence; D054856:G-Quadruplexes; D015394:Molecular Structure; D009696:Nucleic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D009841:Oligonucleotides / Q000737:chemistry*
chemical_list: D009696:Nucleic Acids; D009841:Oligonucleotides; C000611468:acyclic (L)-threninol