title: Mechano-electric heterogeneity of the myocardium as a paradigm of its function.
abstract: Myocardial heterogeneity is well appreciated and widely documented, from sub-cellular to organ levels. This paper reviews significant achievements of the group, led by Professor Vladimir S. Markhasin, Russia, who was one of the pioneers in studying and interpreting the relevance of cardiac functional heterogeneity.
authors.affiliation: Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russia; Ural Federal University, Ekaterinburg, Russia. Electronic address: o.solovyova@iip.uran.ru.
authors.forename: Olga
authors.initials: O
authors.lastname: Solovyova
authors.affiliation: Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russia; Ural Federal University, Ekaterinburg, Russia. Electronic address: leonidkatsnelson51@gmail.com.
authors.forename: Leonid B
authors.initials: LB
authors.lastname: Katsnelson
authors.affiliation: Research Centre for Cardiovascular Medicine, University of Freiburg, Germany; National Heart and Lung Institute, Imperial College of London, UK. Electronic address: kohl@imperial.ac.uk.
authors.forename: Peter
authors.initials: P
authors.lastname: Kohl
authors.affiliation: Department of Physics and Astronomy, Ghent University, Ghent, Belgium. Electronic address: Alexander.Panfilov@UGent.be.
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Panfilov
authors.affiliation: Institute of Mechanics of Moscow State University, Russia. Electronic address: andrey.tsaturyan@gmail.com.
authors.forename: Andrey K
authors.initials: AK
authors.lastname: Tsaturyan
authors.affiliation: Ural State Medical University, Ekaterinburg, Russia. Electronic address: pavel.tsyvian@gmail.com.
authors.forename: Pavel B
authors.initials: PB
authors.lastname: Tsyvian
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D055724:Electrophysiological Phenomena; D006321:Heart / Q000502:physiology*; D006801:Humans; D055595:Mechanical Phenomena; D009206:Myocardium / Q000166:cytology
keywords: Cardiac modeling; Cardiomyocyte; Gradients in the cellular electrical and mechanical properties; Heart; Muscle duplex; Myocardial heterogeneity; Myocardial tissue; Slow force response; Wet and dry experiment