title: Endovascular treatment for iliac vein compression syndrome with or without lower extremity deep vein thrombosis: A retrospective study on mid-term in-stent patency from a single center.
abstract: OBJECTIVE
  The purpose of this study was to evaluate mid-term patency of iliac vein following endovascular treatment for iliac vein compression syndrome (IVCS) with or without deep venous thrombosis (DVT).
  
  
  METHODS
  The authors' institutional review board approved the study. Two hundred and thirty-three consecutive patients with IVCS were treated with endovascular treatment and followed up. The therapeutic strategies and complications were recorded. Cumulative patency was assessed with Kaplan-Meier curves. Independent predictors of in-stent obstruction were calculated with the Cox regression model.
  
  
  RESULTS
  Endovascular treatment was technically successful in 225 of the 233 patients (96.6%). All of 225 patients were treated with percutaneous transluminal angioplasty and stent placement. No severe procedure-related complications occurred. The cumulative 1-, 3- and 5-year primary patency rates over a median follow-up time of 34 months (range, 0.3-82 months) were 93.2%, 84.3% and 74.5%, respectively. Independent predictors for in-stent obstruction included use of multiple stents and irregular stocking wearing. The cumulative 1-, 3-, 5-year secondary patency rates were 100%, 93.3% and 92%, respectively.
  
  
  CONCLUSIONS
  Endovascular treatment could achieve favorable mid-term patency in patients with IVCS with or without DVT.
authors.affiliation: The Department of Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, China; The Department of Vascular Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 210008 Nanjing, China. Electronic address: shwy110@163.com.
authors.forename: Wan-Yin
authors.initials: WY
authors.lastname: Shi
authors.affiliation: The Department of Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, China. Electronic address: gjp_nj@163.com.
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Gu
authors.affiliation: The Department of Vascular Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 210008 Nanjing, China. Electronic address: lcj_nj@163.com.
authors.forename: Chang-Jian
authors.initials: CJ
authors.lastname: Liu
authors.affiliation: The Department of Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, China. Electronic address: hexu_nj@163.com.
authors.forename: Xu
authors.initials: X
authors.lastname: He
authors.affiliation: The Department of Interventional Radiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, China. Electronic address: louwensheng_nj@163.com.
authors.forename: Wen-Sheng
authors.initials: WS
authors.lastname: Lou
mesh_terms: D000368:Aged; D017130:Angioplasty / Q000379:methods*; D000925:Anticoagulants / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007084:Iliac Vein / Q000503:physiopathology*; D035002:Lower Extremity; D008297:Male; D062108:May-Thurner Syndrome / Q000503:physiopathology / Q000628:therapy*; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome; D014654:Vascular Patency; D020246:Venous Thrombosis / Q000503:physiopathology / Q000628:therapy*
chemical_list: D000925:Anticoagulants
keywords: Deep vein thrombosis; Endovascular treatment; Iliac vein compression syndrome; In-stent patency