title: Non-invasive cryolipolysis to reduce subcutaneous fat in the arms.
abstract: BACKGROUND
  Cryolipolysis received U.S. Food and Drug Administration clearance for reducing fat from the flanks, abdomen, and thighs. The upper arms are an off-label indication for cryolipolysis, and outcome data on reducing fat from the arms using a cryolipolytic device has rarely been published.
  
  
  OBJECTIVE
  This pilot study evaluated cryolipolysis to reduce upper arm fat.
  
  
  METHODS
  A flat vacuum applicator was used to treat seven subjects in a single-side study. The patients underwent one cycle of upper-arm cryolipolysis treatment, and the contralateral arm served as a control. Follow-up was conducted at 8 weeks. Equalization treatments were delivered subsequently to the opposite arm. Efficacy was evaluated by ultrasound imaging, physician's assessment, and patient satisfaction. Side effects and adverse events were monitored.
  
  
  RESULTS
  Ultrasound measurements showed a decrease in the fat layer at 83.3% of the 12 measured sites. The mean reduction in fat layer thickness was 15.3%, corresponding to 2.03 mm. A significant difference was detected between baseline and 8-week assessments (p = 0.001).
  
  
  CONCLUSIONS
  One treatment using a flat vacuum cryolipolysis applicator was safe and effective to reduce arm fat.
authors.affiliation: a Arumdaun Nara Dermatologic Clinic , Seoul , Korea.
authors.forename: Sang Jun
authors.initials: SJ
authors.lastname: Lee
authors.affiliation: b Department of Dermatology , Korea University College of Medicine , Ansan , Korea.
authors.forename: Hee Won
authors.initials: HW
authors.lastname: Jang
authors.affiliation: a Arumdaun Nara Dermatologic Clinic , Seoul , Korea.
authors.forename: Hyunjoo
authors.initials: H
authors.lastname: Kim
authors.affiliation: a Arumdaun Nara Dermatologic Clinic , Seoul , Korea.
authors.forename: Dong Hye
authors.initials: DH
authors.lastname: Suh
authors.affiliation: b Department of Dermatology , Korea University College of Medicine , Ansan , Korea.
authors.forename: Hwa Jung
authors.initials: HJ
authors.lastname: Ryu
mesh_terms: D001132:Arm / Q000000981:diagnostic imaging* / Q000601:surgery*; D017679:Cryotherapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015187:Lipectomy / Q000379:methods*; D008297:Male; D017060:Patient Satisfaction; D010865:Pilot Projects; D050151:Subcutaneous Fat / Q000601:surgery*; D016896:Treatment Outcome; D014463:Ultrasonography
keywords: Cryolipolysis; ulnar nerve