title: Comparison of early neonatal valve ablation with vesicostomy in patient with posterior urethral valve.
abstract: BACKGROUND
  To compare the results of final renal function by two methods of treatment in patients diagnosed as posterior urethral valve (PUV) (valve ablation vs. vesicostomy).
  
  
  METHODS
  Fifty-four boys diagnosed with PUV participated in this study. They were divided into top two groups. Thirty-one of the total were treated with primary valve fulguration (Group 1) and 23 were treated with vesicostomy (Group 2). One-year-creatinine level and glomerular filtration rate (GFR) were measured. Also, they were taken ultrasonography detecting hydronephrosis. Data analysed in IBM SPSS21 with t-test and Chi-square test. Presented with 95% of confidence intervals.
  
  
  RESULTS
  Fifty-four boys diagnosed with PUV participated in this study. The mean age of patients in Group 1 was 3.8 ± 1.48 days and Group 2 was 4.7 ± 1.85 days. One-year Cr level was 1.57 ± 1.45 in Group 1 and 1.57 ± 1.45 in Group 2 which was not statistically significant (P < 0.8). Also 1-year GFR level was 31.1 ± 4.4 in Group 1 and 33 ± 4.7% in Group 2 (P < 0.10/23) in Group 2 (43.47%) had severe hydronephrosis and 14/31 (45.16%) in Group 1 had severe hydronephrosis. Graded ultrasound results were not significantly different (P = 0.24).
  
  
  CONCLUSIONS
  The results showed no significant difference. Vesicostomy might be a more favourable method due to less complication and follow-up in early neonatal life. Hence, the condition of the patients and decision of the surgeon are effective parameters in choosing an optimal method in patients diagnosed with PUV.
authors.forename: Seyed Mohammad Vahid
authors.initials: SM
authors.lastname: Hosseini
authors.affiliation: Iranian Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zarenezhad
authors.forename: Mansour
authors.initials: M
authors.lastname: Kamali
authors.forename: Saeed
authors.initials: S
authors.lastname: Gholamzadeh
authors.forename: Babak
authors.initials: B
authors.lastname: Sabet
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Alipour
mesh_terms: D003559:Cystostomy / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D014521:Urethra / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000601:surgery*; D014522:Urethral Diseases / Q000151:congenital / Q000175:diagnosis / Q000601:surgery*; D014567:Urography