title: Role of microRNAs in metastasis of non-small cell lung cancer.
abstract: Lung cancer causes the most number of deaths from cancer. Non-small cell lung cancer (NSCLC), including squamous cell carcinoma, large cell carcinoma, and adenocarcinoma, is responsible for more than 80% of primary lung cancer cases. As metastasis is the main cause of death, understanding the mechanisms underlying NSCLC metastasis are essential for improving the treatment of this disease. Recent studies have found that microRNAs (miRNAs) are involved in the progression from cell invasion and migration to final tumor metastasis of NSCLC. In this review, we will discuss the role and mechanisms of miRNAs related to the metastasis of NSCLC.
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: ShengLei
authors.initials: S
authors.lastname: Li
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Gao
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: ZongMing
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: LiJie
authors.initials: L
authors.lastname: Song
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: XianZheng
authors.initials: X
authors.lastname: Gao
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Han
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: YongFang
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: WenCai
authors.initials: W
authors.lastname: Li
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China.
authors.forename: JianPing
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Pathology, The First Affliated Hospital of ZhengZhou University, ZhengZhou, 450000, China, lslbljys@yeah.net.
authors.forename: XinWei
authors.initials: X
authors.lastname: Han
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics*; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics / Q000473:pathology*; D035683:MicroRNAs / Q000235:genetics*; D009362:Neoplasm Metastasis / Q000235:genetics*
chemical_list: D035683:MicroRNAs