title: Rh(I)-Catalyzed Insertion of Allenes into C-C Bonds of Benzocyclobutenols.
abstract: Herein we report a Rh(I)-catalyzed two carbon insertion into C-C bonds of benzocyclobutenols by employing symmetrical and unsymmetrical allenes. This reaction provides rapid access to alkylidene tetralins bearing two adjacent stereogenic centers in good yields and diasteroselectivities.
authors.affiliation: School of Pharmaceutical Sciences and Tsinghua-Peking Joint Centers for Life Science, Tsinghua University , Beijing 100084, China.
authors.forename: Chunliang
authors.initials: C
authors.lastname: Zhao
authors.affiliation: School of Pharmaceutical Sciences and Tsinghua-Peking Joint Centers for Life Science, Tsinghua University , Beijing 100084, China.
authors.forename: Li-Chuan
authors.initials: LC
authors.lastname: Liu
authors.affiliation: School of Pharmaceutical Sciences and Tsinghua-Peking Joint Centers for Life Science, Tsinghua University , Beijing 100084, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.affiliation: School of Pharmaceutical Sciences and Tsinghua-Peking Joint Centers for Life Science, Tsinghua University , Beijing 100084, China.
authors.forename: Chenran
authors.initials: C
authors.lastname: Jiang
authors.affiliation: School of Pharmaceutical Sciences and Tsinghua-Peking Joint Centers for Life Science, Tsinghua University , Beijing 100084, China.
authors.forename: Qing-Wei
authors.initials: QW
authors.lastname: Zhang
authors.affiliation: School of Pharmaceutical Sciences and Tsinghua-Peking Joint Centers for Life Science, Tsinghua University , Beijing 100084, China.
authors.forename: Wei
authors.initials: W
authors.lastname: He
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D000440:Butanols / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000466:Alkadienes; D000440:Butanols; C025947:propadiene; D002244:Carbon; D012238:Rhodium