title: Choroidal Involvement in Acute Posterior Multifocal Placoid Pigment Epitheliopathy.
abstract: OBJECTIVE
  To evaluate choroidal involvement in acute posterior multifocal placoid pigment epitheliopathy (APMPPE).
  
  
  METHODS
  Retrospective study in five eyes of three patients evaluated through multimodal imaging, including enhanced-depth imaging optical coherence tomography (OCT), ultra-wide field color photography, fundus autofluorescence, and fluorescein angiography (FA). Choroidal thickness and structure were evaluated on OCT.
  
  
  RESULTS
  During the acute phase, choroidal OCT showed choroidal thickening and a lucency at the level of the inner choroid. Subclinical lesions detected in the retinal periphery using wide-field retinal imaging were isoautofluorescent and corresponded to choriocapillaris filling-defects on FA. At final follow-up, all patients showed resolution of choroidal thickening and the inner choroidal lucency, as well as the disappearance of subclinical lesions.
  
  
  CONCLUSIONS
  These results suggest a transient ischemic choroiditis in APMPPE that may lead to secondary permanent retinal pigment epithelium damage in the posterior pole but not in the retinal periphery.
authors.forename: Sarah
authors.initials: S
authors.lastname: Mrejen
authors.forename: David
authors.initials: D
authors.lastname: Sarraf
authors.forename: Saradha
authors.initials: S
authors.lastname: Chexal
authors.forename: Kenneth
authors.initials: K
authors.lastname: Wald
authors.forename: K Bailey
authors.initials: KB
authors.lastname: Freund
mesh_terms: D000208:Acute Disease; D000328:Adult; D015862:Choroid Diseases / Q000175:diagnosis*; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D009887:Ophthalmoscopy; D012164:Retinal Diseases / Q000175:diagnosis*; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D012189:Retrospective Studies; D012607:Scotoma / Q000175:diagnosis; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology