title: Interactions Between Monovalent Cations and Nutrient Homeostasis.
abstract: Maintenance of appropriate fluxes of monovalent cation is a requirement for growth and survival. In the budding yeast Saccharomyces cerevisiae an electrochemical gradient of H(+) is fundamental for the uptake of diverse cations, such as K(+), and of many other nutrients. In spite of early work suggesting that alterations in monovalent cation fluxes impact on the uptake and utilization of nutrients, such as phosphate anions, only recently this important aspect of the yeast physiology has been addressed and characterized in some detail. This chapter provides a historical background and summarizes the latest findings.
authors.affiliation: Departament de Bioquímica i Biologia Molecular & Institut de Biotecnologia i Biomedicina, Universitat Autónoma de Barcelona, Bellaterra, 08193, Barcelona, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Canadell
authors.affiliation: Departament de Bioquímica i Biologia Molecular & Institut de Biotecnologia i Biomedicina, Universitat Autónoma de Barcelona, Bellaterra, 08193, Barcelona, Spain. Joaquin.Arino@uab.es.
authors.forename: Joaquín
authors.initials: J
authors.lastname: Ariño
mesh_terms: D000641:Ammonia / Q000378:metabolism; D001692:Biological Transport; D002414:Cations, Monovalent; D015966:Gene Expression Regulation, Fungal; D006706:Homeostasis / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D010710:Phosphates / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D012964:Sodium / Q000378:metabolism; D050611:Sodium-Phosphate Cotransporter Proteins, Type III / Q000235:genetics / Q000378:metabolism*; D000254:Sodium-Potassium-Exchanging ATPase / Q000235:genetics / Q000378:metabolism*
chemical_list: D002414:Cations, Monovalent; C086375:ENA1 protein, S cerevisiae; C493567:PHO89 protein, S cerevisiae; D010710:Phosphates; D029701:Saccharomyces cerevisiae Proteins; D050611:Sodium-Phosphate Cotransporter Proteins, Type III; D000641:Ammonia; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium
keywords: Ammonium assimilation; Phosphate uptake; Potassium homeostasis; Saccharomyces cerevisiae