title: Practical Tantalum Coating of Microspheres for Experimental Visualization under Fluoroscopy and CT.
abstract: The present report describes a simple technique for tantalum coating of microspheres for visualization by fluoroscopy and computed tomography (CT). Spherical microspheres were soaked with Ta powder under different conditions and microscopically evaluated for Ta-coating quality by assessing bound and unbound Ta. For 100-300-µm Embosphere particles, soaking with 0.05 mL Ta powder for 30 minutes and centrifugation at 500 rpm produced optimal coating. Optimized microspheres were injected in swine renal arteries and assessed by fluoroscopy and micro-CT for the opacification of segmental, arcuate, and interlobular arteries. This practical method can be used for experimental studies with commonly available microspheres.
authors.affiliation: Dotter Interventional Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd., L342, Portland, OR 97239. Electronic address: horikawaradivr@gmail.com.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Horikawa
authors.affiliation: Dotter Interventional Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd., L342, Portland, OR 97239.
authors.forename: Masaki
authors.initials: M
authors.lastname: Ishikawa
authors.affiliation: Dotter Interventional Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd., L342, Portland, OR 97239.
authors.forename: Barry T
authors.initials: BT
authors.lastname: Uchida
authors.affiliation: Dotter Interventional Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd., L342, Portland, OR 97239.
authors.forename: John A
authors.initials: JA
authors.lastname: Kaufman
authors.affiliation: Dotter Interventional Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd., L342, Portland, OR 97239.
authors.forename: Khashayar
authors.initials: K
authors.lastname: Farsad
mesh_terms: D000818:Animals; D005471:Fluoroscopy; D008863:Microspheres; D023421:Models, Animal; D012077:Renal Artery / Q000000981:diagnostic imaging*; D013552:Swine; D013635:Tantalum; D055114:X-Ray Microtomography
chemical_list: D013635:Tantalum