title: Donor Kidney With Renal Cell Carcinoma Successfully Treated With Radiofrequency Ablation: A Case Report.
abstract: BACKGROUND
  The risk of donor-transmitted cancer is evident.
  
  
  METHODS
  We report the case of a 69-year-old woman who was transplanted with a kidney from a deceased donor. Four days after transplantation a routine ultrasound scan revealed a 3-cm tumor in the middle-upper pole of the allograft. A biopsy showed the tumor to be papillary renal cell carcinoma. The patient was treated with radiofrequency ablation. This procedure was complicated by the development of a cutaneous fistula and open surgery was done with resection of an area of necrosis in the kidney and of the fistula. The maintenance immunosuppressive regimen was modified with a change in treatment to everolimus in combination with reduced dose mycophenolate and low-dose steroids. The patient was followed for 4.5 years and during that time she remained dialysis independent with an excellent allograft function (serum creatinine, 95 μmol/L [1.04 mg/dL]).
  
  
  CONCLUSIONS
  To the best of our knowledge, this is the first case in which a donor-transmitted tumor was diagnosed in the renal allograft only 4 days after transplantation and subsequently treated successfully with radiofrequency ablation.
authors.affiliation: Department of Nephrology, Copenhagen University Hospital Herlev, Herlev, Denmark. Electronic address: sarah-fc@hotmail.com.
authors.forename: S F
authors.initials: SF
authors.lastname: Christensen
authors.affiliation: Department of Nephrology, Copenhagen University Hospital Herlev, Herlev, Denmark.
authors.forename: J M
authors.initials: JM
authors.lastname: Hansen
mesh_terms: D000368:Aged; D001706:Biopsy; D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000601:surgery*; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery*; D016030:Kidney Transplantation; D008875:Middle Aged; D014019:Tissue Donors; D066027:Transplant Recipients; D014184:Transplantation, Homologous