title: A versatile water-soluble chelating and radical scavenging platform.
abstract: The phenol-diamide compound, 5-(tert-butyl)-2-hydroxy-N1,N3-bis(2-hydroxyethyl)isophthalamide (), is water-soluble, non-cytotoxic, and capable of both, trapping ROS species and chelating Cu(ii) and Fe(iii) ions; these combined properties confer a protective effect against ROS induced cell death.
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Meital
authors.initials: M
authors.lastname: Eckshtain-Levi
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Ronit
authors.initials: R
authors.lastname: Lavi
authors.affiliation: Department of Chemistry, University of Durham, South Road, Durham DH1 3LE, UK.
authors.forename: Dmitry S
authors.initials: DS
authors.lastname: Yufit
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Bareket
authors.initials: B
authors.lastname: Daniel
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Omer
authors.initials: O
authors.lastname: Green
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Ohad
authors.initials: O
authors.lastname: Fleker
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Michal
authors.initials: M
authors.lastname: Richman
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Shai
authors.initials: S
authors.lastname: Rahimipour
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Arie
authors.initials: A
authors.lastname: Gruzman
authors.affiliation: Department of Chemistry, Bar-Ilan University, Ramat Gan 52900, Israel. benisvy@gmail.com gruzmaa@biu.ac.il.
authors.forename: Laurent
authors.initials: L
authors.lastname: Benisvy
mesh_terms: D002614:Chelating Agents / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry*; D012995:Solubility; D014867:Water / Q000737:chemistry*
chemical_list: D002614:Chelating Agents; D016166:Free Radical Scavengers; D014867:Water