title: Pulmonary metastases from gastric cancer: Is there any indication for lung metastasectomy? A systematic review.
abstract: It is still not clear whether pulmonary resection may have a role in the multidisciplinary management of gastric cancer lung metastases. A systematic literature search was performed to identify all studies published between January 1998 and December 2014 about pulmonary resection of gastric cancer metastases. Ten studies published between 1998 and 2013 were retrieved, including a total of 44 patients. After gastrectomy, median disease-free interval was 35 months. Thirty-eight patients had single lung metastases, whereas six presented with more than one lesion. Median overall survival after lung resection was 45 months, and median disease-free survival was 9 months. Our analysis of the recent literature shows that lung metastasectomy for gastric cancer pulmonary metastases has been reported only in the setting of anecdotic cases or small series of highly selected patients. Lung metastasectomy has no role in the standard management of metastatic gastric patients and may actually be proposed only in individual highly selected cases.
authors.affiliation: Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, UOC Chirurgia 3, via di Grottarossa, 1035-1039, Rome, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Aurello
authors.affiliation: Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, UOC Chirurgia 3, via di Grottarossa, 1035-1039, Rome, Italy. nicpetrucciani@hotmail.it.
authors.forename: Niccolo'
authors.initials: N
authors.lastname: Petrucciani
authors.affiliation: Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, UOC Chirurgia 3, via di Grottarossa, 1035-1039, Rome, Italy.
authors.forename: Diego
authors.initials: D
authors.lastname: Giulitti
authors.affiliation: Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, UOC Chirurgia 3, via di Grottarossa, 1035-1039, Rome, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Campanella
authors.affiliation: Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, UOC Chirurgia 3, via di Grottarossa, 1035-1039, Rome, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: D'Angelo
authors.affiliation: Department of Medical and Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, St Andrea Hospital, Sapienza University, UOC Chirurgia 3, via di Grottarossa, 1035-1039, Rome, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Ramacciato
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery*; D059146:Metastasectomy; D011013:Pneumonectomy; D013274:Stomach Neoplasms / Q000473:pathology*
keywords: Gastric cancer; Lung metastases; Pulmonary metastasectomy