title: Paraneoplastic pemphigus associated with follicular dendritic cell sarcoma: report of a case and review of literature.
abstract: Follicular dendritic cell sarcoma (FDCS) is a rare tumor associated with paraneoplastic pemphigus. It is Blame drenchs auxiliary cell tumor which is derived from the peripheral lymphoid tissues. Throughout the world, several patients of paraneoplastic pemphigus associated follicular dendritic cell sarcoma were reported in the literature, but mostly originated from the neck lymph nodes, and extranodal origin of follicular dendritic sarcoma was rarely reported. Also, so far we have found that the malignant degree of all patients diagnosed with malignant tumors have been reported were low and after combined treatment of surgery, radiotherapy and chemotherapy, most of the prognosis was good. However, here we present a patient of paraneoplastic pemphigus associated with follicular dendritic cell sarcoma origined from outside of the lymph nodes and had high tumor malignant degree for its unclear cell boundaries, obvious atypia and mitoses and the patient's state became progressively deteriorate after operation.
authors.affiliation: Department of Comprehensive, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Su
authors.affiliation: Department of Gastrointestinal Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Gaojie
authors.initials: G
authors.lastname: Liu
authors.affiliation: Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Gynaecology and Obstetrics, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Tingfeng
authors.initials: T
authors.lastname: Fang
authors.affiliation: Department of Pathology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Yunjie
authors.initials: Y
authors.lastname: Zeng
authors.affiliation: Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Huayao
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Shanglin
authors.initials: S
authors.lastname: Yang
authors.affiliation: Department of General Surgery, Shenzhen Hospital of Armed Police Frontier Corps Shenzhen 518029, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Dermatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Junmin
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Hepatobiliary Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Jinxing
authors.initials: J
authors.lastname: Wei
authors.affiliation: Department of Gastrointestinal Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Yingru
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Pathology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University Guangzhou 510120, China.
authors.forename: Youfeng
authors.initials: Y
authors.lastname: Guo
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D054740:Dendritic Cell Sarcoma, Follicular / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D010392:Pemphigus / Q000209:etiology*
keywords: Paraneoplastic; follicular dendritic cell sarcoma; pemphigus