title: Association Between the Neurogenic Bladder Symptom Score and Urodynamic Examination in Multiple Sclerosis Patients With Lower Urinary Tract Dysfunction.
abstract: OBJECTIVE
  To determine the relationship between the neurogenic bladder symptoms score (NBSS) and urodynamic examination in patients affected by multiple sclerosis (MS) and related lower urinary tract dysfunction (LUTD).
  
  
  METHODS
  We recruited 122 consecutive patients with MS in remission and LUTD from January 2011 to September 2013 who underwent their first urodynamic examination. Neurological impairment was assessed using the Expanded Disability Status Scale (EDSS) and bladder symptoms were studied with the NBSS.
  
  
  RESULTS
  Median NBSS was 20.0 (interquartile range, 12.75-31.0). Neurogenic detrusor overactivity (NDO) was discovered in 69 patients (56.6%). The concordance between patients with NDO and maximum detrusor pressure during involuntary detrusor contraction (PdetmaxIDC)≥20.0 cm H2O was 0.89 (κ-Cohen; P<0.05). Patients with EDSS scores of ≥4.5 had a greater NBSS (25.41 vs. 20.19, P<0.05), NBSS-incontinence (8.73 vs. 4.71, P<0.05), NBSS-consequence (4.51 vs. 3.13, P<0.05) and NBSS-quality of life (2.14 vs. 1.65, P<0.05). The NBSS was not associated with PdetmaxIDC≥20 cm H2O (P=0.77) but with maximum cystometric capacity<212 mL (odds ratio, 0.95; P<0.05).
  
  
  CONCLUSIONS
  The NBSS cannot give adequate information the way urodynamic studies can, in patients with MS and LUTD.
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Eugenia
authors.identifier: 0000-0002-4779-2012
authors.initials: E
authors.lastname: Fragalà
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Giorgio Ivan
authors.identifier: 0000-0003-4687-7353
authors.initials: GI
authors.lastname: Russo
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Di Rosa
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Raimondo
authors.initials: R
authors.lastname: Giardina
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Privitera
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Favilla
authors.affiliation: Department G.F. Ingrassia, Section of Neurosciences, University of Catania, Catania, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Patti
authors.affiliation: Division of Urology, Department of Surgery, Western University, London, ON, Canada.
authors.forename: Blayne
authors.initials: B
authors.lastname: Welk
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Cimino
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Tommaso
authors.initials: T
authors.lastname: Castelli
authors.affiliation: Department of Urology, University of Catania, Catania, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Morgia
keywords: Lower Urinary Tract Dysfunction; Multiple Sclerosis; Neurogenic Bladder Symptom Score; Urinary Bladder, Overactive; Urodynamics