title: MicroRNA-induced cascaded and catalytic self-assembly of DNA nanostructures for enzyme-free and sensitive fluorescence detection of microRNA from tumor cells.
abstract: The presence of target microRNA triggers cascaded and catalytic self-assembly of two DNA motifs into DNA nanostructures, which serves as a remarkable signal amplification means for the highly sensitive monitoring of the target microRNA and the detection of low numbers of tumor cells.
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. yunatswu@swu.edu.cn.
authors.forename: Xue
authors.initials: X
authors.lastname: Gong
authors.forename: Wenjiao
authors.initials: W
authors.lastname: Zhou
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Chai
authors.forename: Ruo
authors.initials: R
authors.lastname: Yuan
authors.forename: Yun
authors.initials: Y
authors.lastname: Xiang
mesh_terms: D002384:Catalysis; D004247:DNA / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D061986:MCF-7 Cells; D035683:MicroRNAs / Q000737:chemistry*; D049329:Nanostructures; D009369:Neoplasms / Q000235:genetics*; D012334:RNA, Neoplasm / Q000032:analysis*; D013050:Spectrometry, Fluorescence / Q000379:methods*
chemical_list: D035683:MicroRNAs; D012334:RNA, Neoplasm; D004247:DNA