title: Microwave ablation as palliative treatment of locally recurrent colorectal cancer.
abstract: BACKGROUND
  Patients suffering local recurrence of colorectal cancer which cannot be surgically removed are troubled with severe pain and poor quality of life. The aim of this study is to evaluate the efficacy and safety of computed tomography (CT)-guided microwave ablation (MWA) as palliative treatment for recurrent unresectable colorectal cancer.
  
  
  METHODS
  Thirty-one patients were suffering locally recurrent colorectal cancer underwent MWA with CT guidance. The MWA power was set at 60-80 W, 6-8 min. Effectiveness was evaluated by visual analog scale (VAS) with a follow-up of 6-month. Complications were also recorded.
  
  
  RESULTS
  Technical success was achieved in all patients. Mean VAS preprocedure was 7.10. Mean VAS postprocedure were as follows: 1 week, 2.65 (P < 0.001); 1 month, 0.81 (P < 0.001); 3 months 0.45 (P < 0.001); and 6 months 0.19 (P < 0.001). No serious complications were observed including intestinal fistulas, bladder fistulas, or peripheral vascular or nerve injury.
  
  
  CONCLUSIONS
  CT-guided MWA as treatment of recurrent colorectal cancer can quickly and effectively relieve pain. It is a minimally invasive, safe, and efficient palliative treatment of recurrent colorectal cancer.
authors.forename: W
authors.initials: W
authors.lastname: Li
authors.affiliation: Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250001, Shandong Province, China.
authors.forename: X
authors.initials: X
authors.lastname: Ye
authors.forename: X
authors.initials: X
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.forename: G
authors.initials: G
authors.lastname: Huang
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: X
authors.initials: X
authors.lastname: Han
authors.forename: X
authors.initials: X
authors.lastname: Ni
authors.forename: Z
authors.initials: Z
authors.lastname: Wei
authors.forename: A
authors.initials: A
authors.lastname: Zheng
authors.forename: M
authors.initials: M
authors.lastname: Meng
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017115:Catheter Ablation; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008872:Microwaves; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D010166:Palliative Care; D011183:Postoperative Complications; D011379:Prognosis; D011788:Quality of Life; D025321:Surgery, Computer-Assisted / Q000379:methods*; D015996:Survival Rate; D014057:Tomography, X-Ray Computed