title: The Nuclear Matrix: Fractionation Techniques and Analysis.
abstract: The first descriptions of an insoluble nuclear structure appeared more than 70 years ago, but it is only in recent years that a sophisticated picture of its significance has begun to emerge. Here we introduce multiple methods for the study of the nuclear matrix.
authors.affiliation: Department of Biology, University of York, York YO10 5DD, United Kingdom.
authors.forename: Rosemary H C
authors.initials: RH
authors.lastname: Wilson
authors.affiliation: Department of Biology, University of York, York YO10 5DD, United Kingdom.
authors.forename: Emma L
authors.initials: EL
authors.lastname: Hesketh
authors.affiliation: Department of Biology, University of York, York YO10 5DD, United Kingdom.
authors.forename: Dawn
authors.initials: D
authors.lastname: Coverley
mesh_terms: D000818:Animals; D002458:Cell Fractionation; D002467:Cell Nucleus / Q000737:chemistry / Q000378:metabolism*; D005591:Chemical Fractionation; D006801:Humans; D008854:Microscopy, Electron; D015530:Nuclear Matrix / Q000378:metabolism* / Q000648:ultrastructure; D040901:Proteomics