title: [Relationships between serum Ghrelin and body composition and lipid metabolism-related cytokines among 591 adult Chinese from 3 Provinces].
abstract: OBJECTIVE
  To describe the relationships between serum Ghrelin and body composition and lipid metabolism-related cytokines among Chinese adults.
  
  
  METHODS
  A total of 591 adults younger than 60 years were selected from urban and rural areas of Liaoning, Henan and Hunan Provinces. Height, body weight, waist circumference, hip circumference, body mass index (BMI), waist-hip ratio (WHR), body fat percentage (% BF), blood lipid, serum leptin, Ghrelin and Ca were measured in all samples.
  
  
  RESULTS
  The mean serum Ghrelin concentration in males was 24.12 μg/L and in females 23.62 μg/L. There were no significant differences between different genders. With the increasing concentration in serum Ghrelin, a significant decreasing trend (P < 0.05) was found in waist circumference, BMI, WHR, overweight/obesity rates, central obesity rates, BF%, TC, TG, LDL-C and serum leptin. A significant increasing trend (P < 0.05) was found in HDL-C and ApoA1/ApoB, and no significant change in hip circumference and serum Ca were found. Correlations showed that there was a significant correlation among serum Ghrelin, BMI, waist circumference, WHR, BF%, TC, LDL-C and leptin (P < 0.05).
  
  
  CONCLUSIONS
  Serum Ghrelin level correlates strongly with body composition and lipid metabolism-related cytokines, and can have a more closely associations with BF% and leptin.
authors.forename: Chang
authors.initials: C
authors.lastname: Su
authors.forename: Wenwen
authors.initials: W
authors.lastname: Du
authors.forename: Huijun
authors.initials: H
authors.lastname: Wang
authors.forename: Bing
authors.initials: B
authors.lastname: Zhang
mesh_terms: D000328:Adult; D016632:Apolipoprotein A-I; D044466:Asian People / Q000706:statistics & numerical data*; D001823:Body Composition; D015992:Body Mass Index; D001835:Body Weight; D016207:Cytokines / Q000378:metabolism*; D005260:Female; D054439:Ghrelin / Q000097:blood*; D006801:Humans; D020738:Leptin; D050356:Lipid Metabolism; D008055:Lipids; D008297:Male; D009765:Obesity / Q000208:ethnology; D055105:Waist Circumference; D049629:Waist-Hip Ratio
chemical_list: C505693:APOA1 protein, human; D016632:Apolipoprotein A-I; D016207:Cytokines; D054439:Ghrelin; D020738:Leptin; D008055:Lipids