title: Dieter Falkenhagen (1942-2015): a multifaceted scientist.
abstract: Dieter Falkenhagen was born in 1942 in Dresden, Germany and died in 2015. He specialized in internal medicine and nephrology. Focusing on artificial organ research, he investigated various aspects of the efficacy and safety of hemodialysis and adsorption technologies, including biocompatibility issues related to blood versus surface interactions and the adverse effects of endotoxin contamination. He studied various mathematical models to analyze efficacy and safety, and animal models to help clarify uncertainty issues. Through his studies, adsorbents were developed, resulting in Prometheus, an artificial liver support device. Anticoagulation models, including citrate perfusion, were improved and made safer by his work. He also stepped into bioreactor research to increase efficacy of liver support devices.
authors.affiliation: Department of Public Health and Clinical Medicine, Umea University, Umea - Sweden.
authors.forename: Bernd
authors.initials: B
authors.lastname: Stegmayr
authors.affiliation: Rostock - Germany.
authors.forename: Horst
authors.initials: H
authors.lastname: Klinkmann
mesh_terms: D001672:Biocompatible Materials; D005858:Germany; D006801:Humans; D017093:Liver Failure / Q000628:therapy*; D019164:Liver, Artificial; D006435:Renal Dialysis / Q000379:methods*
chemical_list: D001672:Biocompatible Materials