title: Two new sesquiterpenes from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities.
abstract: Two new sesquiterpenes, nicotianasesterpenes A and B (1 and 2), together with five known sesquiterpenes (3-7) were isolated from the leaves of Nicotiana tabacum. Their structures were determined mainly by spectroscopic methods, including extensive 1D- and 2D-NMR techniques. The anti-tobacco mosaic virus (anti-TMV) activities of compounds 1-7 were evaluated. The results revealed that compound 1 exhibited high anti-TMV activities with inhibition rates of 33.6%. This rate is high than that of positive control. The other compounds also showed potential activities with inhibition rates in the range of 18.8-28.4%, respectively.
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.
authors.forename: Qinpeng
authors.initials: Q
authors.lastname: Shen
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.|b School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Nature Products , Kunming Medical University , Kunming , P.R. China.
authors.forename: Xingmeng
authors.initials: X
authors.lastname: Xu
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.
authors.forename: Chunbo
authors.initials: C
authors.lastname: Liu
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.
authors.forename: Nengjun
authors.initials: N
authors.lastname: Xiang
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.
authors.forename: Yongkuan
authors.initials: Y
authors.lastname: Chen
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.
authors.forename: Mingming
authors.initials: M
authors.lastname: Miao
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Liu
authors.affiliation: a Key Laboratory of Tobacco Chemistry of Yunnan Province , China Tobacco Yunnan Industrial Co., Ltd , Kunming , P.R. China.
authors.forename: Guangyu
authors.initials: G
authors.lastname: Yang
keywords: Nicotiana tabacum; anti-tobacco mosaic virus activity; sesquiterpenes