title: Co-existence of chronic non-communicable diseases and common neoplasms among 2,462 endocrine adult inpatients - a retrospective analysis.
abstract: OBJECTIVE
  To analyze the coexistence of chronic non-communicable diseases (NCDs) and common neoplasms among endocrine adult inpatients.
  
  
  METHODS
  The retrospective analysis was performed using clinical data of 2,462 adult patients (2,003 women and 459 men), hospitalized in the reference endocrine department. Diagnoses of 18 types of benign tumours and 16 types of malignant tumours, together with the most common 25 NCDs and demographic parameters, were all collected from the medical records. The most frequently found 6 types of benign tumours (of thyroid, pituitary, uterus, breast, adrenal and prostate) and 4 types of malignant tumours (of thyroid, breast, prostate and uterus) were taken for further statistical analyses.
  
  
  RESULTS
  Age predicted the existence of accumulated as well as individual types of benign and malignant tumours, whereas BMI predicted the occurrence of accumulated and some individual types of benign tumours. Accumulated as well as individual types of benign and malignant tumours coexisted more frequently with several NCDs, such as diabetes, hypertension, metabolic syndrome, osteoporosis, Graves' disease, coronary artery disease, state after cholecystectomy, thus being disorders usually resulting from excessive exposure to harmful environmental factors. The most distinct coexistence was found between breast cancer and metabolic syndrome, between breast cancer and Graves' disease, between cancer of the uterus and type 2 diabetes, between cancer of the uterus and metabolic syndrome, and between cancer of the uterus and dyslipidemia.
  
  
  CONCLUSIONS
  The results obtained indicate a significant relationship between the most common NCDs and several cancers in endocrine adult patients, which suggests that the prevention of the former may reduce the frequency of the latter.
authors.affiliation: Department of Oncological Endocrinology, Medical University of Lodz, Poland; Polish Mother's Memorial Hospital & Research Institute, Lodz, Poland.
authors.forename: Paweł
authors.initials: P
authors.lastname: Szychta
authors.affiliation: Department of Oncological Endocrinology, Medical University of Lodz, Poland; 1st Chair and Department of Cardiology, Medical University of Warsaw, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Szychta
authors.affiliation: Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Poland; Polish Mother's Memorial Hospital & Research Institute, Lodz, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Lewiński
authors.affiliation: Department of Oncological Endocrinology, Medical University of Lodz, Poland; Polish Mother's Memorial Hospital & Research Institute, Lodz, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Karbownik-Lewińska
mesh_terms: D000328:Adult; D002908:Chronic Disease / Q000453:epidemiology*; D015897:Comorbidity; D005260:Female; D006801:Humans; D007297:Inpatients / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology; D011044:Poland / Q000453:epidemiology; D012189:Retrospective Studies; D055815:Young Adult