title: Preoperative Platelet to Lymphocyte Ratio Is Associated with Early Morbidity and Mortality after Coronary Artery Bypass Grafting.
abstract: OBJECTIVE
  To investigate the association of platelet to lymphocyte ratio to mortality and morbidity after coronary artery bypass grafting operation.
  
  
  METHODS
  We evaluated records of 916 patients who underwent coronary artery bypass grafting operation between January 2009 and May 2014 retrospectively. Patients were grouped as Group 1 (n = 604) if the platelet to lymphocyte ratio was above 142 and Group 2 (n = 312) if platelet to lymphocyte ratio was below 142.
  
  
  RESULTS
  The number of patients who developed a neurologic event during the hospital stay and in the first postoperative month was 7 (1.2%) in Group 1 and 12 (3.8%) in Group 2 for which the difference was statistically significant (P = .007). Early term mortality occurred in 3 patients (0.5%) in Group 1 and in 10 patients (3.2%) in Group 2 for which the difference was statistically highly significant (P = .001). In univariate and multivariate regression analysis, the preoperative platelet to lymphocyte ratio was determined as an independent risk factor for occurrence of atrial fibrillation in the early postoperative period, reoperation for sternum dehiscence, occurrence of a neurologic event, prolonged stay in the hospital and mortality.
  
  
  CONCLUSIONS
  In this study, elevated levels of platelet to lymphocyte ratio were associated with mortality and morbidity after coronary artery bypass grafting operation.
authors.affiliation: Department of Cardiovascular Surgery, Derince Training and Research Hospital, Kocaeli, Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Şaşkın
authors.affiliation: Department of Cardiovascular Surgery, Derince Training and Research Hospital, Kocaeli, Turkey.
authors.forename: Çagrı
authors.initials: Ç
authors.lastname: Düzyol
authors.affiliation: Department of Cardiology, Derince Training and Research Hospital, Kocaeli, Turkey.
authors.forename: Kazım Serhan
authors.initials: KS
authors.lastname: Özcan
authors.affiliation: Department of Cardiovascular Surgery, Derince Training and Research Hospital, Kocaeli, Turkey.
authors.forename: Rezan
authors.initials: R
authors.lastname: Aksoy
authors.affiliation: Department of Cardiovascular Surgery, Acibadem Hospital, Kocaeli, Turkey, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Idiz
mesh_terms: D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality*; D005260:Female; D006801:Humans; D007902:Length of Stay; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011183:Postoperative Complications / Q000401:mortality; D057234:Preoperative Period; D012189:Retrospective Studies; D012307:Risk Factors