title: Future Implications of Human Embryonic Testing and Modification: Great Medicine or GATTACA?
abstract: The past several decades have seen tremendous advances in the field of medical genetics. Currently, the application of genetic testing on human embryos determines if embryos harbor a lethal condition or a serious genetic disease. The purpose of this sort of testing is not to "improve" the offspring of a couple. Rather, current testing strategies focus on helping couples to have a healthy family in an efficient manner. Newly emerging technologies have opened the door to test embryos for an exponentially growing number of traits. Additionally, recent reports describe the actual modification of human embryonic DNA. The implications from the application of this technology are many and have the potential to fundamentally change the social paradigm of the human experience. Embryonic testing and modification does have the potential to accomplish good and is not inherently amoral. However, thoughtful consideration should be given by scientists, legislators, and the general population on how to apply this technology in a manner that is both appropriate and equitable and does not result in further social stratification and polarization, both within individual nations and the global community.
authors.affiliation: Obstetrics and Gynecology; Division of Reproductive Endocrinology and Infertility, Vanderbilt University School of Medicine, Nashville, TN, USA; Fertility Associates of Memphis, Reproductive Genetics, Memphis, TN, USA. paul.r.brezina@vanderbilt.edu.
authors.forename: Paul R
authors.initials: PR
authors.lastname: Brezina
authors.forename: Enrico
authors.initials: E
authors.lastname: Marinelli
authors.forename: Amelia P
authors.initials: AP
authors.lastname: Bailey
mesh_terms: D000026:Abortion, Habitual; D004622:Embryo, Mammalian; D005820:Genetic Testing; D006801:Humans; D027724:Reproductive Techniques, Assisted