title: [Predictive value of fasting plasma glucose and body mass index of pre-pregnancy women for gestational diabetes mellitus].
abstract: OBJECTIVE
  To analyze the relationship between fasting plasma glucose (FPG) and body mass index (BMI) of pre-pregnancy women and the occurrence of gestational diabetes mellitus(GDM), and to explore a effective method for GDM screening.
  
  
  METHODS
  This was a retrospective clinical study including the pregnant women who underwent screening for GDM recently and also participated in national free preconception health examination at three medical centers. They were divided into normal group and GDM group base on the 2011 diagnosis criteria for GDM of our country.
  
  
  RESULTS
  FPG, BMI and diastolic blood pressure before pregnancy in GDM group were significantly higher than those in normal group (P<0.01). Multiple logistic-regression showed that the women with higher FPG and BMI level before pregnancy had higher risk of diagnosis of GDM. The receiver operating characteristic (ROC) curves showed that the area under the curve (AUC) were 0.600 and 0.632 for FPG and BMI, respectively, in predicting GDM (P<0.01).
  
  
  CONCLUSIONS
  The FPG and BMI level of women before pregnancy are valuable predictors for early diagnosis of GDM.
authors.affiliation: Shandong Provincial Key Laboratory for Improving Birth Outcome Technique, Shandong Provincial Research Institute for Family Planning, Jinan 250002, China; Email: lihong01118@126.com.
authors.forename: Lihong
authors.initials: L
authors.lastname: Zhang
authors.forename: Qiuju
authors.initials: Q
authors.lastname: Wang
authors.forename: Yongan
authors.initials: Y
authors.lastname: Qu
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Yanping
authors.initials: Y
authors.lastname: Zhang
authors.forename: Baohong
authors.initials: B
authors.lastname: Jiang
authors.forename: Haiqing
authors.initials: H
authors.lastname: Ding
mesh_terms: D019540:Area Under Curve; D001786:Blood Glucose; D015992:Body Mass Index; D016640:Diabetes, Gestational; D005215:Fasting; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D011247:Pregnancy; D012372:ROC Curve; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D001786:Blood Glucose