title: Metal-organic frameworks supported surface-imprinted nanoparticles for the sensitive detection of metolcarb.
abstract: A novel approach to synthesize molecularly imprinted polymer (MIP) nanoparticles using a MIL-101 support (a type of metal-organic framework) is reported herein for the first time; the sample is referred as MIL@MIP. The nanoparticles were well distributed within the polymer film, and exhibit an octahedral shape, satisfied thermal stability, and a high specific surface area (SSA) of 1579.43 m(2)g(-1). The adsorption behavior of MIL@MIP toward metolcarb in aqueous solution was subsequently examined. The synthesized MIL@MIP displayed satisfactory high transfer mass rates and a high selective adsorption affinity for metolcarb. Based on these results, a quartz crystal microbalance (QCM) sensor based on MIL@MIP was subsequently constructed and examined for the sensitive detection of metolcarb. Under optimal conditions, the detection limit of the system assessed in pear juice was 0.0689 mg L(-1) within a linear concentration range of 0.1-0.9 mg L(-1). MIL@MIP-QCM system combines the advantages of MIL-101 and molecularly imprinted technology (MIT), thereby achieving high detection sensitivity and selectivity. The current findings suggest the potential of MIL@MIP for detecting trace level pesticides and veterinary drugs for food safety and environmental control.
authors.affiliation: College of Chemical Engineering and Materials Science, Tianjin University of Science and Technology, Tianjin 300457, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Qian
authors.affiliation: College of Chemical Engineering and Materials Science, Tianjin University of Science and Technology, Tianjin 300457, China.
authors.forename: Qiliang
authors.initials: Q
authors.lastname: Deng
authors.affiliation: Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.
authors.forename: Guozhen
authors.initials: G
authors.lastname: Fang
authors.affiliation: Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.
authors.forename: Junping
authors.initials: J
authors.lastname: Wang
authors.affiliation: Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China.
authors.forename: Mingfei
authors.initials: M
authors.lastname: Pan
authors.affiliation: Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin Key Laboratory of Food Nutrition and Safety, Tianjin University of Science and Technology, Tianjin 300457, China. Electronic address: s.wang@tust.edu.cn.
authors.forename: Shuo
authors.initials: S
authors.lastname: Wang
authors.affiliation: Institute of Food Science and Technology, Yunnan Agricultural University, Yunnan 650201, China.
authors.forename: Yuehong
authors.initials: Y
authors.lastname: Pu
mesh_terms: D000327:Adsorption; D015374:Biosensing Techniques / Q000379:methods*; D056831:Coordination Complexes / Q000737:chemistry; D057230:Limit of Detection; D000073396:Metal-Organic Frameworks; D008670:Metals / Q000737:chemistry; D054802:Molecular Imprinting; D053758:Nanoparticles / Q000737:chemistry; D010575:Pesticides / Q000302:isolation & purification; D048448:Phenylcarbamates / Q000302:isolation & purification*; D011108:Polymers / Q000737:chemistry; D058525:Quartz Crystal Microbalance Techniques / Q000379:methods*
chemical_list: D056831:Coordination Complexes; C000589635:MIL-101; D000073396:Metal-Organic Frameworks; D008670:Metals; D010575:Pesticides; D048448:Phenylcarbamates; D011108:Polymers; C532346:metolcarb
keywords: MIL-101; Metal–organic frameworks; Metolcarb; Molecularly imprinted polymer; Quartz crystal microbalance sensor; Sol–gel