title: Radical C-H functionalization to construct heterocyclic compounds.
abstract: Heterocyclic compounds are widely present in natural products, pharmaceuticals and bioactive molecules. Thus, organic and pharmaceutical chemists have been making extensive efforts to construct those heterocyclic frameworks through developing versatile and efficient synthetic strategies. The direct C-H functionalization via the radical pathway has emerged as a promising and dramatic approach towards heterocycles with high atom- and step-economy. Heterocyclic compounds such as coumarins, furans, benzofurans, xanthones, benzothiazoles, indoles, indolines, oxindoles, quinolines, isoquinolines, quinoxaline, and phenanthridines have been successfully synthesized by C-H functionalization through the radical pathway. In this review, recent advances on radical C-H functionalization to construct heterocyclic compounds are highlighted with discussions.
authors.affiliation: School of Petrochemical Engineering, Advanced Catalysis and Green Manufacturing Collaborative Innovation Center, Changzhou University, Changzhou 213164, P. R. China. yujintao@cczu.edu.cn.
authors.forename: Jin-Tao
authors.initials: JT
authors.lastname: Yu
authors.affiliation: School of Chemistry & Environmental Engineering, Jiangsu University of Technology, Changzhou 213001, P. R. China. panchangduo@jsut.edu.cn.
authors.forename: Changduo
authors.initials: C
authors.lastname: Pan