title: Design of Bioprosthetic Aortic Valves using biaxial test data.
abstract: Bioprosthetic Aortic Valves (BAVs) do not have the serious limitations of mechanical aortic valves in terms of thrombosis. However, the lifetime of BAVs is too short, often requiring repeated surgeries. The lifetime of BAVs might be improved by using computer simulations of the structural behavior of the leaflets. The goal of this study was to develop a numerical model applicable to the optimization of durability of BAVs. The constitutive equations were derived using biaxial tensile tests. Using a Fung model, stress and strain data were computed from biaxial test data. SolidWorks was used to develop the geometry of the leaflets, and ABAQUS finite element software package was used for finite element calculations. Results showed the model is consistent with experimental observations. Reaction forces computed by the model corresponded with experimental measurements when the biaxial test was simulated. As well, the location of maximum stresses corresponded to the locations of frequent tearing of BAV leaflets. Results suggest that BAV design can be optimized with respect to durability.
authors.forename: Y
authors.initials: Y
authors.lastname: Dabiri
authors.forename: K
authors.initials: K
authors.lastname: Paulson
authors.forename: J
authors.initials: J
authors.lastname: Tyberg
authors.forename: J
authors.initials: J
authors.lastname: Ronsky
authors.forename: I
authors.initials: I
authors.lastname: Ali
authors.forename: E
authors.initials: E
authors.lastname: Di Martino
authors.forename: K
authors.initials: K
authors.lastname: Narine
mesh_terms: D001021:Aortic Valve / Q000502:physiology*; D003198:Computer Simulation; D020342:Finite Element Analysis; D006350:Heart Valve Prosthesis; D011474:Prosthesis Design; D013314:Stress, Mechanical; D013718:Tensile Strength