title: Toward an automated method for optical coherence tomography characterization.
abstract: With the increasing use of optical coherence tomography (OCT) in biomedical applications, robust yet simple methods for calibrating and benchmarking a system are needed. We present here a procedure based on a calibration object complemented with an algorithm that analyzes three-dimensional OCT datasets to retrieve key characteristics of an OCT system. The calibration object combines state-of-the-art tissue phantom material with a diamond-turned aluminum multisegment mirror. This method is capable of determining rapidly volumetric field-of-view, axial resolution, and image curvature. Moreover, as the phantom material mimics biological tissue, the system’s signal and noise levels can be evaluated in conditions close to biological experiments. We believe this method could improve OCT quantitative data analysis and help OCT data comparison for longitudinal or multicenter studies.
authors.affiliation: École Polytechnique de Montréal, Department of Engineering Physics, 6079 succursale Centre-ville, Montréal, Quebec H3C 3A7, Canada.
authors.forename: Mathias
authors.initials: M
authors.lastname: Strupler
authors.affiliation: École Polytechnique de Montréal, Department of Engineering Physics, 6079 succursale Centre-ville, Montréal, Quebec H3C 3A7, Canada.
authors.forename: Amber M
authors.initials: AM
authors.lastname: Beckley
authors.affiliation: École Polytechnique de Montréal, Department of Engineering Physics, 6079 succursale Centre-ville, Montréal, Quebec H3C 3A7, Canada.
authors.forename: Fouzi
authors.initials: F
authors.lastname: Benboujja
authors.affiliation: Institut National d'Optique, 2740 Einstein Street, Ville de Québec, Quebec G1P 4S4, Canada.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Dubois
authors.affiliation: Institut National d'Optique, 2740 Einstein Street, Ville de Québec, Quebec G1P 4S4, Canada.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Noiseux
authors.affiliation: Institut National d'Optique, 2740 Einstein Street, Ville de Québec, Quebec G1P 4S4, Canada.
authors.forename: Ozzy
authors.initials: O
authors.lastname: Mermut
authors.affiliation: Institut National d'Optique, 2740 Einstein Street, Ville de Québec, Quebec G1P 4S4, Canada.
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Bouchard
authors.affiliation: École Polytechnique de Montréal, Department of Engineering Physics, 6079 succursale Centre-ville, Montréal, Quebec H3C 3A7, Canada.
authors.forename: Caroline
authors.initials: C
authors.lastname: Boudoux
mesh_terms: D000465:Algorithms; D000535:Aluminum / Q000737:chemistry; D001331:Automation; D002138:Calibration; D004867:Equipment Design; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D010363:Pattern Recognition, Automated; D019047:Phantoms, Imaging; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio; D012984:Software; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D000535:Aluminum