title: [THRESHOLD VALUES OF MAIN PARAMETERS OF THE BLOOD PRESSURE DIURNAL PROFILE IN MEN WITH ISOLATED CLINICAL ARTERIAL HYPERTENSION LIVING BEYOND THE ARCTIC CIRCLE].
abstract: The purpose was to calculate thresholds of diurnal blood pressure parameters (BP) in men with isolated clinical hypertension (ICH) living beyond the Arctic circle, and selection of those parameters that will be particularly informative for differential diagnostics of ICH and essential hypertension (EH) in this contingent. Fifty male subjects were distributed in the ICH group (n = 25) and normotensive group with one and more cardiovascular risk factors (n = 25). No drug therapy was provided during diurnal BP monitoring (DBPM). ICH was diagnosed in the event of increased office BP, normal DBPM values and self-monitoring of BP (BPSM). ROC-analysis was applied to calculate thresholds of the BP diurnal profile for men with ICH and identify the most useful ones. Specifically, these include the following thresholds: average daily systolic BP (SBP) (> 122 mm Hg), average daytime SBP (> 127 mm Hg) and average nighttime SBP (> 108 mmHg), and SBP time indices over 24 hrs. (> 16.7%) and daytime (> 14.4 %). The range of scatter of these values allows differential diagnostics of both ICH and EH which is important for health expertise of male dwellers in the region. Early ICH detection in men with high cardiovascular risks and prescription of anti-hypertension therapy will reduce the probability of ICH progression to stable hypertension, prevent damage to target-organs and mitigate the total cardiovascular risk.
authors.forename: K B
authors.initials: KB
authors.lastname: Solovieva
authors.forename: I V
authors.initials: IV
authors.lastname: Dolbin
mesh_terms: D000328:Adult; D001110:Arctic Regions / Q000453:epidemiology; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D055815:Young Adult