title: Glutathione is key to the synergistic enhancement of doxorubicin and etoposide by polyphenols in leukaemia cell lines.
authors.affiliation: Biomolecular Sciences Research Centre, The Department of Biosciences and Chemistry, Faculty of Health and Wellbeing, Sheffield Hallam University, Howard Street, Sheffield, South Yorkshire S1 1WB, UK.
authors.forename: A A
authors.initials: AA
authors.lastname: Mahbub
authors.affiliation: Biomolecular Sciences Research Centre, The Department of Biosciences and Chemistry, Faculty of Health and Wellbeing, Sheffield Hallam University, Howard Street, Sheffield, South Yorkshire S1 1WB, UK.
authors.forename: C L
authors.initials: CL
authors.lastname: Le Maitre
authors.affiliation: Biomolecular Sciences Research Centre, The Department of Biosciences and Chemistry, Faculty of Health and Wellbeing, Sheffield Hallam University, Howard Street, Sheffield, South Yorkshire S1 1WB, UK.
authors.forename: S L
authors.initials: SL
authors.lastname: Haywood-Small
authors.affiliation: Biomolecular Sciences Research Centre, The Department of Biosciences and Chemistry, Faculty of Health and Wellbeing, Sheffield Hallam University, Howard Street, Sheffield, South Yorkshire S1 1WB, UK.
authors.forename: N A
authors.initials: NA
authors.lastname: Cross
authors.affiliation: Biomolecular Sciences Research Centre, The Department of Biosciences and Chemistry, Faculty of Health and Wellbeing, Sheffield Hallam University, Howard Street, Sheffield, South Yorkshire S1 1WB, UK.
authors.forename: N
authors.initials: N
authors.lastname: Jordan-Mahy
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology*; D045744:Cell Line, Tumor; D004317:Doxorubicin / Q000008:administration & dosage / Q000494:pharmacology*; D004357:Drug Synergism; D005047:Etoposide / Q000008:administration & dosage / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism*; D006801:Humans; D019169:Jurkat Cells; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000378:metabolism*; D007951:Leukemia, Myeloid / Q000188:drug therapy* / Q000378:metabolism; D059808:Polyphenols / Q000008:administration & dosage / Q000494:pharmacology*; D059005:Topoisomerase II Inhibitors / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D059808:Polyphenols; D059005:Topoisomerase II Inhibitors; D005047:Etoposide; D004317:Doxorubicin; D005978:Glutathione