title: Intraoperative measurement of parathyroid hormone: A Copernican revolution in the surgical treatment of hyperparathyroidism.
abstract: Intraoperative parathyroid hormone (PTH) monitoring in the setting of the operating room represents a valuable example of the rationale use of the laboratory diagnostic in a patient-oriented approach. Rapid intraoperative PTH (ioPTH) assay is a valid tool for an accurate evaluation of the success of parathyroid surgery. The reliability of the user-friendly portable systems as well as the collaboration between operators and surgical staff allow the one-site monitoring of the ioPTH decrements on the course of the surgical management of hyperparathyroidism. The rapid answer provided by an effective decrement of PTH during parathyroidectomy contributes dramatically to the efficacy of parathyroid surgery and the reduction of the number of re-operations. Therefore the dose of ioPTH is a valid and reliable support for the success of the intervention of parathyroidectomy at controlled costs.
authors.affiliation: AUOP "P. Giaccone" Universitary Hospital, University of Palermo, Italy.
authors.forename: Maria Concetta
authors.initials: MC
authors.lastname: Gioviale
authors.affiliation: AUOP "P. Giaccone" Universitary Hospital, University of Palermo, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Damiano
authors.affiliation: AUOP "P. Giaccone" Universitary Hospital, University of Palermo, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Altomare
authors.affiliation: AUOP "P. Giaccone" Universitary Hospital, University of Palermo, Italy.
authors.forename: Carolina
authors.initials: C
authors.lastname: Maione
authors.affiliation: PhD Course in Experimental Oncology and Surgery, University of Palermo, Italy; Department of Surgical, Oncological and Stomatological Disciplines (DICHIRONS), University of Palermo, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Buscemi
authors.affiliation: AUOP "P. Giaccone" Universitary Hospital, University of Palermo, Italy; Department of Surgical, Oncological and Stomatological Disciplines (DICHIRONS), University of Palermo, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Buscemi
authors.affiliation: AUOP "P. Giaccone" Universitary Hospital, University of Palermo, Italy; Department of Surgical, Oncological and Stomatological Disciplines (DICHIRONS), University of Palermo, Italy. Electronic address: attilioignazio.lomonte@unipa.it.
authors.forename: Attilio Ignazio
authors.initials: AI
authors.lastname: Lo Monte
mesh_terms: D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood / Q000601:surgery*; D016343:Monitoring, Intraoperative; D010281:Parathyroid Hormone / Q000097:blood*; D016105:Parathyroidectomy; D012086:Reoperation; D015203:Reproducibility of Results
chemical_list: D010281:Parathyroid Hormone
keywords: Hyperparathyroidism; Intraoperative PTH assay; Parathyroid hormone