title: [Alterations of brain network efficiency in patients with post-concussion syndrome].
abstract: OBJECTIVE
  To discuss the alterations of brain network efficiency in patients with post-concussion syndrome.
  
  
  METHODS
  A total of 23 patients from Anhui Provincial Hospital in the period from 2013/6 to 2014/3 who have had the concussion for 3 months were enrolled and 23 volunteers paired in sex, age and education were also enrolled as healthy controls. Comparisons of selective attention of both groups were conducted using Stroop Word-Color Test. The data of resting-state functional magnetic resonance imaging (fMRI) in both groups were collected and the data were dealt with Network Construction which is a part of GRETNA software to obtain the Matrix of brain network. Network analysis was used to obtain Global and Nodal efficiency, then independent t-test was used for statistical analyses of the value of Global and Nodal efficiency.
  
  
  RESULTS
  The difference in Global efficiency of two groups in every threshold value had no statistical significance. Compared with healthy controls, the Nodal efficiencies in patients with post-concussion syndrome were significantly different in the brain regions as below: left orbital middle frontal gyrus, left posterior cingulate, left lingual, left thalamus, left superior temporal gyrus, right anterior cingulate, right posterior cingulate, right supramarginalgyrus.
  
  
  CONCLUSIONS
  Compared with healthy controls, there is no significant changes of Globe efficiency in patients with post-concussion syndrome, and the brain function deficits in these patients may be caused by changes of Nodal efficiency in their brain network.
authors.affiliation: Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China.
authors.forename: Nan
authors.initials: N
authors.lastname: Peng
authors.forename: Ruobing
authors.initials: R
authors.lastname: Qian
authors.affiliation: Email: fuxianming@163.com.
authors.forename: Xianming
authors.initials: X
authors.lastname: Fu
authors.forename: Shunli
authors.initials: S
authors.lastname: Li
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Kang
authors.forename: Bin
authors.initials: B
authors.lastname: Lin
authors.forename: Xuebing
authors.initials: X
authors.lastname: Ji
authors.forename: Xiangpin
authors.initials: X
authors.lastname: Wei
authors.forename: Chaoshi
authors.initials: C
authors.lastname: Niu
authors.forename: Yehan
authors.initials: Y
authors.lastname: Wang
mesh_terms: D001288:Attention; D001921:Brain; D006801:Humans; D008279:Magnetic Resonance Imaging; D038223:Post-Concussion Syndrome