title: Extensive Bone Reaction From Catastrophic Oxidized Zirconium Wear.
abstract: The use of alternative bearing surfaces for total hip arthroplasty has become popular to minimize wear and increase longevity, especially in young patients. Oxidized zirconium (Oxinium; Smith & Nephew, Memphis, Tennessee) femoral heads were introduced in the past decade for use in total hip arthroplasty. The advantages of oxidized zirconium include less risk of fracture compared with traditional ceramic heads. This case report describes a patient with a history of bilateral avascular necrosis of the femoral head after chemotherapy for acute lymphoblastic leukemia. Nonoperative management of avascular necrosis failed, and the patient was treated with bilateral total hip arthroplasty. The patient was followed at regular intervals and had slow eccentric polyethylene wear during a 10-year period. After 10 years, the patient had accelerated wear, with femoral and acetabular bone changes as a result of Oxinium and ultrahigh-molecular-weight polyethylene wear during a 6-month period. This article highlights the unusual accelerated bone changes that occurred as a result of Oxinium wear particles.
authors.forename: Adrian J
authors.initials: AJ
authors.lastname: Cassar-Gheiti
authors.forename: Dennis
authors.initials: D
authors.lastname: Collins
authors.forename: Tom
authors.initials: T
authors.lastname: McCarthy
mesh_terms: D000077:Acetabulum; D000328:Adult; D019644:Arthroplasty, Replacement, Hip; D002516:Ceramics; D019544:Equipment Failure Analysis; D005270:Femur Head; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000601:surgery*; D006801:Humans; D008297:Male; D010084:Oxidation-Reduction; D011095:Polyethylenes / Q000009:adverse effects* / Q000737:chemistry; D011475:Prosthesis Failure / Q000209:etiology*; D013997:Time Factors; D015040:Zirconium / Q000009:adverse effects* / Q000737:chemistry
chemical_list: D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; D015040:Zirconium