title: Conversion of 2'-substituted chalcones in the presence of BSA as evidenced by ¹H NMR studies.
abstract: The emergence of albumin as a biocatalyst has created continuous interest of researchers for its application not only in the field of asymmetric oxidations and reductions but also in chemical reactions such as additions, condensations and eliminations. In the present work we report the cyclization reactions in presence of an albumin protein, Bovine Serum Albumin (BSA). The work is focused on cyclization of 2'-hydroxychalcone and 2'-aminochalcone to flavanones and azaflavanone, respectively. The results are supported by (1)H NMR studies.
authors.affiliation: Department of Chemistry, Kurukshetra University, Kurukshetra 136119, India. Electronic address: nraghav.chem@gmail.com.
authors.forename: Neera
authors.initials: N
authors.lastname: Raghav
authors.affiliation: Department of Chemistry, Kurukshetra University, Kurukshetra 136119, India.
authors.forename: Shweta
authors.initials: S
authors.lastname: Garg
authors.affiliation: Department of Chemistry, Kurukshetra University, Kurukshetra 136119, India.
authors.forename: Indu
authors.initials: I
authors.lastname: Ravish
mesh_terms: D047188:Chalcones / Q000138:chemical synthesis / Q000737:chemistry*; D044950:Flavanones / Q000138:chemical synthesis / Q000737:chemistry; D066244:Proton Magnetic Resonance Spectroscopy; D012710:Serum Albumin, Bovine / Q000737:chemistry*
chemical_list: D047188:Chalcones; D044950:Flavanones; D012710:Serum Albumin, Bovine; C013031:2'-hydroxychalcone
keywords: Azaflavanones; BSA; Chalcones; Cyclization; Flavanones