title: Gastrografin as an alternative booster to sodium phosphate in colon capsule endoscopy: safety and efficacy pilot study.
abstract: OBJECTIVE
  Sodium phosphate is a key component of bowel preparation regimen for colon capsule endoscopy (CCE), but may cause serious complications. The aim of this study is to evaluate the use of Gastrografin, substituted for sodium phosphate, in CCE bowel preparation.
  
  
  METHODS
  In total, 29 patients (median age 64 years; 23 females) underwent CCE, covered by the national health insurance system of Japan. All had a history of laparotomy and/or previously incomplete colonoscopy. On the day before examination, patients ingested 1 L of polyethylene glycol + ascorbic acid with 0.5 L of water in the evening, and again the same laxative on the morning of examination. After capsule ingestion, 50 mL of Gastrografin diluted with 0.9 L of magnesium citrate was administered, and then repeated after 1 hour.
  
  
  RESULTS
  The capsule excretion rate was 97 % (28/29). The median colon transit time was 2 hours 45 minutes and rapid transit (< 40 minutes) through the colon occurred in one patient (3.4 %). Bowel cleansing level was adequate in 90 % of patients. The polyp (≥ 6 mm) detection rate was 52 %. Diluted Gastrografin was well tolerated by patients. No adverse events occurred.
  
  
  CONCLUSIONS
  Gastrografin can be an alternative to sodium phosphate in CCE bowel preparation regimen.
authors.affiliation: Department of Coloproctology, Aizu Medical Center, Fukushima Medical University, Aizuwakamatsu-city, Japan.
authors.forename: Kazutomo
authors.initials: K
authors.lastname: Togashi
authors.affiliation: Department of Gastroenterology, Otaru Ekiseikai General Hospital, Otaru, Japan.
authors.forename: Tomoki
authors.initials: T
authors.lastname: Fujita
authors.affiliation: Department of Coloproctology, Aizu Medical Center, Fukushima Medical University, Aizuwakamatsu-city, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Utano
authors.affiliation: Department of Gastroenterology, Otaru Ekiseikai General Hospital, Otaru, Japan.
authors.forename: Eriko
authors.initials: E
authors.lastname: Waga
authors.affiliation: Department of Gastroenterology, Otaru Ekiseikai General Hospital, Otaru, Japan.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Katsuki
authors.affiliation: Department of Coloproctology, Aizu Medical Center, Fukushima Medical University, Aizuwakamatsu-city, Japan.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Isohata
authors.affiliation: Department of Coloproctology, Aizu Medical Center, Fukushima Medical University, Aizuwakamatsu-city, Japan.
authors.forename: Shungo
authors.initials: S
authors.lastname: Endo
authors.affiliation: Department of Surgery, Jichi Medical University, Shimotsuke, Japan.
authors.forename: Alan K
authors.initials: AK
authors.lastname: Lefor