title: Pattern of Blood Pressure Response in Patients With Severe Asymptomatic Hypertension Treated in the Emergency Department.
abstract: Severe asymptomatic hypertension (SAH) is a common cause of emergency department (ED) visits. Despite recommendations against using short-acting blood pressure (BP)-lowering drugs in the ED, it is still a common practice. The authors characterized BP response in the ED utilizing 24-hour ambulatory BP monitoring (ABPM). Patients with SAH who were not admitted to the hospital were recruited. All patients underwent 24-hour ABPM. A total of 21 patients (14 females) with a mean age of 58±16 years were studied. BP decreased from 199±16/101±17 mm Hg to 154±34/83±23 mm Hg after 5 hours but then rose to 174±25/94±17 mm Hg after 19 hours. In 17 patients, systolic BP was ≥180 mm Hg after 6.7±5.3 hours. Two patients experienced severe hypotension (systolic BP <90 mm Hg). Thus, data from a single site in Israel support the current recommendations for management of SAH in the ED.
authors.affiliation: Department of Internal Medicine C, Emek Medical Center, Afula, Israel.|Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel.
authors.forename: Wasseem
authors.initials: W
authors.lastname: Rock
authors.affiliation: Department of Internal Medicine C, Emek Medical Center, Afula, Israel.|Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel.
authors.forename: Khaled
authors.initials: K
authors.lastname: Zbidat
authors.affiliation: Clinical Research Unit, Emek Medical Center, Afula, Israel.|School of Public Health, University of Haifa, Haifa, Israel.
authors.forename: Naama
authors.initials: N
authors.lastname: Schwartz
authors.affiliation: Department of Internal Medicine C, Emek Medical Center, Afula, Israel.|Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel.
authors.forename: Mazen
authors.initials: M
authors.lastname: Elias
authors.affiliation: Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel.|Department of Emergency Medicine, Emek Medical Center, Afula, Israel.
authors.forename: Itamar
authors.initials: I
authors.lastname: Minuhin
authors.affiliation: Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, Israel.|Department of Emergency Medicine, Emek Medical Center, Afula, Israel.
authors.forename: Reuma
authors.initials: R
authors.lastname: Shapira
authors.affiliation: Department of Internal Medicine D and Hypertension Unit, The Chaim Sheba Medical Center, Tel-Hashomer, Israel.|Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Ehud
authors.initials: E
authors.lastname: Grossman
mesh_terms: D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects*; D018660:Blood Pressure Monitoring, Ambulatory; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents