title: Spontaneous rupture of primary splenic angiosarcoma: A case report.
abstract: Primary angiosarcoma of the spleen is an extremely rare malignant neoplasm of vascular origin that often has a poor prognosis. The majority of cases presents with splenic rupture and hemorrhage. The present study retrospectively analyzed the case of 77-year-old female who presented with diffuse abdominal pain and distension. During laparotomy, a huge actively bleeding spleen was identified and a splenectomy was performed. Since an accurate diagnosis could not be achieved by abdominal computed tomography, a pathological examination was performed. The patient and the family refused post-operative adjuvant chemotherapy and radiation therapy. The patient succumbed to uncontrolled hemorrhagic shock and lung metastases at 2 weeks post-surgery.
authors.affiliation: Division of General Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China ; Department of General Surgery, Zhuji City People's Hospital of Zhejiang Province, Zhuji, Zhejiang, P.R. China.
authors.forename: Botao
authors.initials: B
authors.lastname: Xu
authors.affiliation: Pulmonary Division, Wenzhou Traditional Chinese Medicine Hospital, Wenzhou, Zhejiang, P.R. China.
authors.forename: Xiaona
authors.initials: X
authors.lastname: Xie
authors.affiliation: Division of General Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China.
authors.forename: Xiong
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Division of General Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China.
authors.forename: Menghe
authors.initials: M
authors.lastname: Zhai
authors.affiliation: Division of General Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, P.R. China.
authors.forename: Wenjun
authors.initials: W
authors.lastname: Yang
keywords: clinical characteristics; primary splenic angiosarcoma; radiographic features; splenic rupture