title: Risk Factors for Death of Elderly Patients with Acute Obstructive Suppurative Cholangitis.
abstract: OBJECTIVE
  To identify the risk factors for death of elderly patients with acute obstructive suppurative cholangitis (AOSC).
  
  
  METHODS
  Three hundred and forty-eight AOSC patients > 60 years of age were retrospectively analysed in the First People's Hospital of Jining from June 2005 to June 2013. The patients were treated with endoscopic retrograde cholangiopancreatography (ERCP) immediately after AOSC was diagnosed to clear the stones and drain, and surgical procedures were then performed in the patients in whom ERCP failed. The risk factors were identified with univariate and multivariate analysis.
  
  
  RESULTS
  Among the 348 AOSC patients, 27 patients died after treatment. Two hundred and forty-nine patients were treated with ERCP, and 11 patients died; 99 patients were treated with ERCP plus surgery, and 16 patients died. Two hundred and thirty-two patients were treated within 24 hours after they were admitted to the hospital, and 10 patients died; 116 patients were treated beyond 24 hours, and 17 patients died. According to the results of the univariate and multivariate analysis, shock, ERCP plus surgery, advanced age, low platelet count, the presence of co-morbidities, door to treatment time > 24 hours, hypoproteinaemia, and hyperbilirubinaemia were the independent risk factors for death of elderly patients with AOSC.
  
  
  CONCLUSIONS
  The strategies of dealing with these risk factors should be researched to reduce mortality of elderly patients with AOSC.
authors.affiliation: Department of Hepatobiliary Surgery, the First People's Hospital of Jining, Jining, China.
authors.forename: C L
authors.initials: CL
authors.lastname: Ma
authors.affiliation: Neonatal Unit, the First People's Hospital of Jining, Jining, China, e-mail: wanglipei888@163. com.
authors.forename: L P
authors.initials: LP
authors.lastname: Wang
authors.affiliation: Department of Hepatobiliary Surgery, the First People's Hospital of Jining, Jining, China.
authors.forename: S
authors.initials: S
authors.lastname: Qiao
authors.affiliation: Department of General Surgery, the People's Hospital of Zoucheng, Zoucheng, China.
authors.forename: X F
authors.initials: XF
authors.lastname: Wang
authors.affiliation: Mental Disease Hospital of Jining, Jining, China.
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Hepatobiliary Surgery, the First People's Hospital of Jining, Jining, China.
authors.forename: R J
authors.initials: RJ
authors.lastname: Sun
authors.affiliation: Department of Hepatobiliary Surgery, the First People's Hospital of Jining, Jining, China.
authors.forename: J G
authors.initials: JG
authors.lastname: Liu
authors.affiliation: Department of Hepatobiliary Surgery, the First People's Hospital of Jining, Jining, China.
authors.forename: Y C
authors.initials: YC
authors.lastname: Li
keywords: Acute obstructive suppurative cholangitis; death; elderly patients; risk factors