title: Copper-catalyzed arylation of alkyl halides with arylaluminum reagents.
abstract: We report a Cu-catalyzed coupling between triarylaluminum reagents and alkyl halides to form arylalkanes. The reaction proceeds in the presence of N,N,N',N'-tetramethyl-o-phenylenediamine (NN-1) as a ligand in combination with CuI as a catalyst. This catalyst system enables the coupling of primary alkyl iodides and bromides with electron-neutral and electron-rich triarylaluminum reagents and affords the cross-coupled products in good to excellent yields.
authors.affiliation: Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131, USA.
authors.forename: Bijay
authors.initials: B
authors.lastname: Shrestha
authors.affiliation: Department of Chemistry & Chemical Biology, The University of New Mexico, Albuquerque, NM 87131, USA.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Giri
keywords: alkylation; arylalkanes; copper; cross-coupling; organoaluminum