title: [Changes of blood fatty acid in women with obesity and type 2 diabetes mellitus].
abstract: Obesity and type 2 diabetes (DM2) in women are accompanied by atherogenic dyslipidemia, with the activation of lipid peroxidation (LPO), as well as disturbances in the antioxidant defense system (ADS). DM2 due to imbalance in LPO-ADS is accompanied by a high concentration of LPO products, decreased parameters of antioxidant systems and timpaired utilization of glucose by cells. The results obtained in this study suggest an important role of fatty acids and their metabolites in the pathogenesis of obesity and DM2, which should be taken into consideration during design and selection of appropriate preventive and therapeutic measures aimed at prevention or elimination of the violations.
authors.affiliation: Pirogov Russian National Research Medical University, Moscow, Russia.
authors.forename: N P
authors.initials: NP
authors.lastname: Mikaelyan
authors.affiliation: Pirogov Russian National Research Medical University, Moscow, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Terentev
authors.affiliation: Pirogov Russian National Research Medical University, Moscow, Russia.
authors.forename: K H
authors.initials: KH
authors.lastname: Nguen
authors.affiliation: Moscow Regional SRI Obstatrics and Ginecology, Moscow, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Mikaelyan
authors.affiliation: Moscow Regional SRI Obstatrics and Ginecology, Moscow, Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Novikova
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D050171:Dyslipidemias / Q000097:blood*; D005227:Fatty Acids / Q000097:blood*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D009765:Obesity / Q000097:blood*
chemical_list: D005227:Fatty Acids
keywords: diabetes mellitus; fatty acids; glucose utilization; insulin resistance; obesity; oxidative stress