title: Decitabine enhances chemosensitivity of early T-cell precursor-acute lymphoblastic leukemia cell lines and patient-derived samples.
authors.affiliation: a Perlmutter Cancer Center , New York University Langone Medical Center , New York , NY , USA ; Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA ;
authors.forename: Benjamin Y
authors.initials: BY
authors.lastname: Lu
authors.affiliation: b Perlmutter Cancer Center , New York University Langone Medical Center , New York , NY , USA ;
authors.forename: Shivani U
authors.initials: SU
authors.lastname: Thanawala
authors.affiliation: b Perlmutter Cancer Center , New York University Langone Medical Center , New York , NY , USA ;
authors.forename: Kelly C
authors.initials: KC
authors.lastname: Zochowski
authors.affiliation: c Division of Hematology/Oncology/Blood and Marrow Transplant, Department of Pediatrics , Medical College of Wisconsin and Children's Hospital of Wisconsin , Milwaukee , WI , USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Burke
authors.affiliation: b Perlmutter Cancer Center , New York University Langone Medical Center , New York , NY , USA ;
authors.forename: William L
authors.initials: WL
authors.lastname: Carroll
authors.affiliation: b Perlmutter Cancer Center , New York University Langone Medical Center , New York , NY , USA ;
authors.forename: Teena
authors.initials: T
authors.lastname: Bhatla
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology*; D001374:Azacitidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects / Q000235:genetics; D000077209:Decitabine; D004357:Drug Synergism; D015973:Gene Expression Regulation, Leukemic / Q000187:drug effects; D006801:Humans; D019169:Jurkat Cells; D051379:Mice; D009363:Neoplasm Proteins / Q000235:genetics; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D020395:Receptors, Interleukin-7 / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D023041:Xenograft Model Antitumor Assays
chemical_list: D000970:Antineoplastic Agents; D001374:Azacitidine; D051792:Basic Helix-Loop-Helix Proteins; D000077209:Decitabine; D009363:Neoplasm Proteins; D020395:Receptors, Interleukin-7; C086541:LYL1 protein, human