title: Coexistence of Papillary Thyroid Carcinoma With Thyroid MALT Lymphoma in a Patient With Hashimoto's Thyroiditis: A Clinical Case Report.
abstract: Papillary thyroid carcinoma (PTC) is the most common type of thyroid neoplasias; however, primary thyroid gland lymphoma (PTL) is uncommon and their simultaneous occurrence is very rare.Herein, we reported a 25-year-old female patient with Hashimoto's thyroiditis (HT), who developed a small goiter with a palpable 1.2-cm nodule in the right lobe. A fine-needle aspiration (FNA) biopsy revealed atypical follicular epithelial cells and lymphoid cells in a background of lymphocytic thyroiditis. A total thyroidectomy was performed. The pathology showed multicentric papillary thyroid carcinoma, concomitant thyroid mucosa-associated lymphoid tissue (MALT) lymphoma, and Hashimoto's thyroiditis. Postoperatively, he received chemotherapy and radioactive iodine ablation treatment. Nowadays the thyroglobulin of the patient is undetectable, without recurrences at 2 years of follow-up.It is concluded that the PTC and MALT lymphoma can exist concomitantly, especially in patients with HT. For the diagnostic workup and optional management of this rare coexistence, a multidisciplinary approach and close surveillance are needed.
authors.affiliation: From the Department of Nuclear Medicine, West China Hospital of Sichuan University, No.37, Guoxue Alley, Chengdu, Sichuan (GS, SH, BL, AK); and Department of Nuclear Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277, Yan Ta Road, Xi'an, Shanxi, People's Republic of China (TJ).
authors.forename: Guohua
authors.initials: G
authors.lastname: Shen
authors.forename: Ting
authors.initials: T
authors.lastname: Ji
authors.forename: Shuang
authors.initials: S
authors.lastname: Hu
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Anren
authors.initials: A
authors.lastname: Kuang
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000150:complications* / Q000473:pathology; D002291:Carcinoma, Papillary; D005260:Female; D050031:Hashimoto Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000150:complications* / Q000473:pathology; D000077273:Thyroid Cancer, Papillary; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology; D013965:Thyroidectomy