title: Metabolites from nematophagous fungi and nematicidal natural products from fungi as alternatives for biological control. Part II: metabolites from nematophagous basidiomycetes and non-nematophagous fungi.
abstract: In this second section of a two-part mini-review article, we introduce 101 further nematicidal and non-nematicidal secondary metabolites biosynthesized by nematophagous basidiomycetes or non-nematophagous ascomycetes and basidiomycetes. Several of these compounds have promising nematicidal activity and deserve further and more detailed analysis. Thermolides A and B, omphalotins, ophiobolins, bursaphelocides A and B, illinitone A, pseudohalonectrins A and B, dichomitin B, and caryopsomycins A-C are excellent candidates or lead compounds for the development of biocontrol strategies for phytopathogenic nematodes. Paraherquamides, clonostachydiol, and nafuredins offer promising leads for the development of formulations against the intestinal nematodes of ruminants.
authors.affiliation: Institute for Insect Biotechnology, Justus-Liebig-University of Giessen, Heinrich-Buff-Ring 26-32, D-35392, Giessen, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Degenkolb
authors.affiliation: Institute for Insect Biotechnology, Justus-Liebig-University of Giessen, Heinrich-Buff-Ring 26-32, D-35392, Giessen, Germany. Andreas.Vilcinskas@agrar.uni-giessen.de.|Department of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Winchester Strasse 2, D-35394, Giessen, Germany. Andreas.Vilcinskas@agrar.uni-giessen.de.
authors.forename: Andreas
authors.initials: A
authors.lastname: Vilcinskas
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000302:isolation & purification* / Q000494:pharmacology*; D001203:Ascomycota / Q000737:chemistry*; D001487:Basidiomycota / Q000737:chemistry*; D001688:Biological Products / Q000302:isolation & purification* / Q000494:pharmacology*; D009348:Nematoda / Q000187:drug effects* / Q000502:physiology; D010944:Plants / Q000469:parasitology; D016019:Survival Analysis
chemical_list: D000871:Anthelmintics; D001688:Biological Products
keywords: Biocontrol; Nematicides; Nematophagous fungi; Phytoparasitic nematodes; Secondary metabolites