title: The Proteomic Characterization of Plasma or Serum from HIV-Infected Patients.
abstract: Proteomics holds great promise for uncovering disease-related markers and mechanisms in human disorders. Recent advances have led to efficient, sensitive, and reproducible methods to quantitate the proteome in biological samples. Here we describe the techniques for processing, running, and analyzing samples from HIV-infected plasma or serum through quantitative mass spectroscopy.
authors.affiliation: Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 42nd and Emile, Omaha, NE, 68198, USA.
authors.forename: Nicole A
authors.initials: NA
authors.lastname: Haverland
authors.affiliation: Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 42nd and Emile, Omaha, NE, 68198, USA.
authors.forename: Lance M
authors.initials: LM
authors.lastname: Villeneuve
authors.affiliation: Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 42nd and Emile, Omaha, NE, 68198, USA.
authors.forename: Pawel
authors.initials: P
authors.lastname: Ciborowski
authors.affiliation: Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 42nd and Emile, Omaha, NE, 68198, USA. hfox@unmc.edu.
authors.forename: Howard S
authors.initials: HS
authors.lastname: Fox
mesh_terms: D001499:Bayes Theorem; D015658:HIV Infections / Q000097:blood*; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D020543:Proteome / Q000032:analysis; D040901:Proteomics / Q000379:methods*
chemical_list: D020543:Proteome
keywords: Bayesian; HIV; Mass spectroscopy; Plasma; Proteomics; SWATH-MS; Serum; Z-score