title: Diastereoselective Synthesis of 3,4-Benzomorphan Derivatives via Tandem [5 + 1]/Hemiaminalization of (2-Aminoaryl)divinyl Ketones.
abstract: A novel tandem formal [5 + 1]/hemiaminalization reaction based on the readily available (2-aminoaryl)divinyl ketones and various nucleophiles has been developed. The reaction represents a highly efficient and convenient methodology for the synthesis of 3,4-benzomorphan derivatives with high diastereoselectivity, and three new bonds and two rings are successively formed in one step under mild, metal-free conditions.
authors.affiliation: Department of Chemistry, Northeast Normal University , Changchun 130024, China.
authors.forename: Yifei
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Chemistry, Northeast Normal University , Changchun 130024, China.
authors.forename: Chengjie
authors.initials: C
authors.lastname: Feng
authors.affiliation: Department of Chemistry, Northeast Normal University , Changchun 130024, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Shi
authors.affiliation: Department of Chemistry, Northeast Normal University , Changchun 130024, China.
authors.forename: Xianxiu
authors.initials: X
authors.lastname: Xu