title: Transradial arterial chemoembolization reduces complications and costs in patients with hepatocellular carcinoma.
abstract: OBJECTIVE
  To improve patient comfort and reduce complications, clinical benefit of a transradial approach for transcatheter arterial chemoembolization (TACE) was evaluated in patients with hepatocellular carcinoma (HCC).
  
  
  METHODS
  A total of 284 patients with HCC for TACE was divided into transradial approach group (n = 126) and transfemoral approach group (n = 158). These two groups of cases were retrospectively compared with regard to complications, the procedural time, X-ray exposure time, length of hospitalization, and hospital costs.
  
  
  RESULTS
  There were lower incidence rates of complications including abdominal distension (42.85% vs. 87.97%, P> 0.001), vomiting (53.17% vs. 77.22%, P < 0.001), lumbago (1.59% vs. 97.46%, P < 0.001), and dysuria (0% vs. 62.03%, P < 0.001) in the transradial group as compared with the transfemoral group. The time required for catheterization and total X-ray exposure time were less in the transradial group compared with the transfemoral group (Pall < 0.001). The hospital stay time and costs required for catheterization were less in the transradial group compared with the transfemoral group (P < 0.001 and P = 0.001, respectively). In addition, hepatic angiography and TACE were completed in 100% and 99.2% cases in transfemoral and transradial groups, respectively.
  
  
  CONCLUSIONS
  Transradial approach for TACE improves quality of life in patients with HCC by offering fewer complications and lower costs compared with transfemoral approach.
authors.forename: T
authors.initials: T
authors.lastname: Wu
authors.forename: R
authors.initials: R
authors.lastname: Sun
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: X
authors.initials: X
authors.lastname: Yin
authors.forename: Z
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: Department of Interventional Radiology, The First Affiliated Hospital of Henan University, Kaifeng, Henan 475001, PR, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Zhao
authors.affiliation: Department of Gastrointestinal Medicine, The First Affiliated Hospital of Henan University, Kaifeng, Henan 475001, PR, China.
authors.forename: J
authors.initials: J
authors.lastname: He
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000191:economics* / Q000473:pathology / Q000628:therapy; D016461:Chemoembolization, Therapeutic / Q000191:economics*; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization / Q000191:economics* / Q000706:statistics & numerical data; D006801:Humans; D007269:Injections, Intra-Arterial; D008113:Liver Neoplasms / Q000098:blood supply / Q000191:economics* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D017534:Radial Artery; D012189:Retrospective Studies