title: Is glucose-6-phosphate dehydrogenase deficiency more prevalent in Carrion's disease endemic areas in Latin America?
abstract: Glucose-6-phosphate dehydrogenase (G6PD) is a cytoplasmic enzyme with an important function in cell oxidative damage prevention. Erythrocytes have a predisposition towards oxidized environments due to their lack of mitochondria, giving G6PD a major role in its stability. G6PD deficiency (G6PDd) is the most common enzyme deficiency in humans; it affects approximately 400 million individuals worldwide. The overall G6PDd allele frequency across malaria endemic countries is estimated to be 8%, corresponding to approximately 220 million males and 133 million females. However, there are no reports on the prevalence of G6PDd in Andean communities where bartonellosis is prevalent.
authors.affiliation: School of Medicine, Research Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru.
authors.forename: Fernando
authors.initials: F
authors.lastname: Mazulis
authors.affiliation: School of Medicine, Research Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru.
authors.forename: Claudia
authors.initials: C
authors.lastname: Weilg
authors.affiliation: School of Medicine, Research Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru.
authors.forename: Carlos
authors.initials: C
authors.lastname: Alva-Urcia
authors.affiliation: School of Medicine, Research Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru.
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Pons
authors.affiliation: School of Medicine, Research Center of the Health Sciences Faculty, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru. Electronic address: jdelvall@upc.edu.pe.
authors.forename: Juana
authors.initials: J
authors.lastname: Del Valle Mendoza
keywords: Bartonella; Febrile syndrome; G6PD; Glucose-6-phosphate dehydrogenase