title: Design optimization of neuroendoscopic continuum instruments for third ventriculostomy and tumor biopsy.
abstract: A simulation-based approach to the design of procedure-specific dexterous neuroendoscopic continuum instruments for endoscopic third ventriculostomy and tumor biopsy is proposed. Given pre-operative CT and MRI images, the algorithm returns instrument design specifications including lengths, curvatures and alternative positions for the surgical incision while respecting anatomical boundaries. This methodology proposes a novel clinically-guided geometric representation of surgical targets specific to this indication. The additional constraints imposed by the presence of surgical trocars and endoscopes are also considered. Finally, we conclude with a clinical example to demonstrate the proposed approach.
authors.forename: Kyle W
authors.initials: KW
authors.lastname: Eastwood
authors.forename: Thomas
authors.initials: T
authors.lastname: Looi
authors.forename: Hani E
authors.initials: HE
authors.lastname: Naguib
authors.forename: James M
authors.initials: JM
authors.lastname: Drake
mesh_terms: D000465:Algorithms; D001706:Biopsy / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D006801:Humans; D008279:Magnetic Resonance Imaging; D008962:Models, Theoretical; D009369:Neoplasms / Q000175:diagnosis*; D044583:Neuroendoscopy / Q000295:instrumentation* / Q000379:methods; D014696:Ventriculostomy / Q000379:methods*