title: Wearable technology and ECG processing for fall risk assessment, prevention and detection.
abstract: Falls represent one of the most common causes of injury-related morbidity and mortality in later life. Subjects with cardiovascular disorders (e.g., related to autonomic dysfunctions and postural hypotension) are at higher risk of falling. Autonomic dysfunctions increasing the risk of falling in the short and mid-term could be assessed by Heart Rate Variability (HRV) extracted by electrocardiograph (ECG). We developed three trials for assessing the usefulness of ECG monitoring using wearable devices for: risk assessment of falling in the next few weeks; prevention of imminent falls due to standing hypotension; and fall detection. Statistical and data-mining methods are adopted to develop classification and regression models, validated with the cross-validation approach. The first classifier based on HRV features enabled to identify future fallers among hypertensive patients with an accuracy of 72% (sensitivity: 51.1%, specificity: 80.2%). The regression model to predict falls due to orthostatic dropdown from HRV recorded before standing achieved an overall accuracy of 80% (sensitivity: 92%, specificity: 90%). Finally, the classifier to detect simulated falls using ECG achieved an accuracy of 77.3% (sensitivity: 81.8%, specificity: 72.7%). The evidence from these three studies showed that ECG monitoring and processing could achieve satisfactory performances compared to other system for risk assessment, fall prevention and detection. This is interesting as differently from other technologies actually employed to prevent falls, ECG is recommended for many other pathologies of later life and is more accepted by senior citizens.
authors.forename: Paolo
authors.initials: P
authors.lastname: Melillo
authors.forename: Rossana
authors.initials: R
authors.lastname: Castaldo
authors.forename: Giovanna
authors.initials: G
authors.lastname: Sannino
authors.forename: Ada
authors.initials: A
authors.lastname: Orrico
authors.forename: Giuseppe
authors.initials: G
authors.lastname: de Pietro
authors.forename: Leandro
authors.initials: L
authors.lastname: Pecchia
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control*; D057225:Data Mining; D015716:Electrocardiography, Ambulatory / Q000295:instrumentation / Q000379:methods; D006801:Humans; D011187:Posture / Q000502:physiology; D018570:Risk Assessment; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*