title: Significant reduction of central line-associated bloodstream infection rates in a tertiary neonatal unit.
abstract: To evaluate the effectiveness of a quality initiative in reducing central line-associated bloodstream infections (CLABSIs) in our neonatal intensive care unit, we designed a prospective study (January 2012-September 2013) estimating CLABSI incidence before and after our implementation. CLABSI rates were significantly decreased after our intervention, from 12 cases per 1,000 central vascular catheter (CVC) days during the preinterventional period to 3.4 cases per 1,000 CVC days during the postinterventional period (P = .004).
authors.affiliation: 2nd NICU and Neonatology Department, General Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: dimitrisrallis@hotmail.com.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Rallis
authors.affiliation: 2nd NICU and Neonatology Department, General Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Paraskevi
authors.initials: P
authors.lastname: Karagianni
authors.affiliation: 2nd NICU and Neonatology Department, General Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Ifigeneia
authors.initials: I
authors.lastname: Papakotoula
authors.affiliation: 2nd NICU and Neonatology Department, General Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Nikolaidis
authors.affiliation: 2nd NICU and Neonatology Department, General Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Christos
authors.initials: C
authors.lastname: Tsakalidis
mesh_terms: D055499:Catheter-Related Infections / Q000453:epidemiology*; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008297:Male; D011446:Prospective Studies; D018805:Sepsis / Q000453:epidemiology*; D062606:Tertiary Care Centers
keywords: Central line–associated bloodstream infection; central vascular catheters; neonatal intensive care unit