title: Multi-Unit Activity contains information about spatial stimulus structure in mouse primary visual cortex.
abstract: This study investigates the spatial and directional tuning of Multi-Unit Activity (MUA) in mouse primary visual cortex and how MUA can reflect spatiotemporal structures contained in moving gratings. Analysis of multi-shank laminar electrophysiological recordings from mouse primary visual cortex indicates a directional preference for moving gratings around 180°, while preferred spatial frequency peaks around 0.02 cycles per degree, which is similar as reported in single-unit studies. Using only features from MUA, we further achieved a significant performance in decoding spatial frequency or direction of moving gratings, with average decoding performances of up to 58.54% for 8 directions, and 44% correctly identified spatial frequencies against chance level of 16.7%.
authors.forename: Marie
authors.initials: M
authors.lastname: Tolkiehn
authors.forename: Simon R
authors.initials: SR
authors.lastname: Schultz
mesh_terms: D000200:Action Potentials; D000818:Animals; D005074:Evoked Potentials, Visual; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D010775:Photic Stimulation; D012815:Signal Processing, Computer-Assisted; D013028:Space Perception; D065855:Spatial Processing; D014793:Visual Cortex / Q000502:physiology*