title: What indication, morbidity and mortality for central pancreatectomy in oncological surgery? A systematic review.
abstract: Conventional pancreatic resections for pancreatic neck and body diseases include pancreaticoduodenectomy, distal pancreatectomy with or without splenectomy, and total pancreatectomy. Recent studies have reported encouraging results of non-traditional pancreatic resections, including central pancreatectomy (CP), for central pancreatic disease. This surgical approach offers the potentials of low postoperative morbidity and preservation of metabolic functions. This study performs a systematic review on CP. A comprehensive literature search was conducted, for the period 1992-2015, on three worldwide databases: PubMed, Scopus, ISI-Web of Knowledge. We focused on indications, morbidity and mortality of this surgical procedure. The review shows that CP is particularly suitable for small-medium size diseases localized into the pancreatic body. This procedure is associated with an increased postoperative morbidity but an excellent postoperative pancreatic function. CP is a safe and effective procedure when performed following the right indications.
authors.affiliation: Department of Advanced Biomedical Sciences-UO General Surgery, University Federico II of Naples, Naples, Italy. Electronic address: michele.santangelo@unina.it.
authors.forename: Michele
authors.initials: M
authors.lastname: Santangelo
authors.affiliation: Department of Advanced Biomedical Sciences-UO General Surgery, University Federico II of Naples, Naples, Italy. Electronic address: annettae@alice.it.
authors.forename: Anna
authors.initials: A
authors.lastname: Esposito
authors.affiliation: Department of Advanced Biomedical Sciences-UO General Surgery, University Federico II of Naples, Naples, Italy. Electronic address: vincenzo.tammaro@unina.it.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Tammaro
authors.affiliation: Department of Advanced Biomedical Sciences-UO General Surgery, University Federico II of Naples, Naples, Italy. Electronic address: armando.calogero2@unina.it.
authors.forename: Armando
authors.initials: A
authors.lastname: Calogero
authors.affiliation: Division of Early Drug Development for Innovative Therapies, Istituto Europeo di Oncologia, Milan, Italy. Electronic address: carmen.criscitiello@ieo.it.
authors.forename: Carmen
authors.initials: C
authors.lastname: Criscitiello
authors.affiliation: Department of Advanced Biomedical Sciences-UO Medical Physics and Statistics, University Federico II of Naples, Naples, Italy. Electronic address: roberti@unina.it.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Roberti
authors.affiliation: Department of Advanced Biomedical Sciences-UO General Surgery, University Federico II of Naples, Naples, Italy. Electronic address: mariacandida84@libero.it.
authors.forename: Maria
authors.initials: M
authors.lastname: Candida
authors.affiliation: Department of Advanced Biomedical Sciences-UO General Surgery, University Federico II of Naples, Naples, Italy. Electronic address: rupenicco@icloud.com.
authors.forename: Niccolò
authors.initials: N
authors.lastname: Rupealta
authors.affiliation: Department of Public Health-UO Nephrology, University Federico II of Naples, Naples, Italy. Electronic address: antonio.pisani13@gmail.com.
authors.forename: Antonio
authors.initials: A
authors.lastname: Pisani
authors.affiliation: Department of Advanced Biomedical Sciences-UO General Surgery, University Federico II of Naples, Naples, Italy. Electronic address: nicola.anita@tiscali.it.
authors.forename: Nicola
authors.initials: N
authors.lastname: Carlomagno
mesh_terms: D006801:Humans; D010179:Pancreas / Q000601:surgery; D010180:Pancreatectomy / Q000009:adverse effects* / Q000379:methods* / Q000401:mortality; D010182:Pancreatic Diseases / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000601:surgery*; D011183:Postoperative Complications
keywords: Central pancreatectomy; Pancreatic fistula; Pancreatic insufficiency; Segmental resection pancreas