title: High titer gluconic acid fermentation by Aspergillus niger from dry dilute acid pretreated corn stover without detoxification.
abstract: This study reported a high titer gluconic acid fermentation using dry dilute acid pretreated corn stover (DDAP) hydrolysate without detoxification. The selected fermenting strain Aspergillus niger SIIM M276 was capable of inhibitor degradation thus no detoxification on pretreated corn stover was required. Parameters of gluconic acid fermentation in corn stover hydrolysate were optimized in flasks and in fermentors to achieve 76.67 g/L gluconic acid with overall yield of 94.91%. The sodium gluconate obtained from corn stover was used as additive for extending setting time of cement mortar and similar function was obtained with starch based sodium gluconate. This study provided the first high titer gluconic acid production from lignocellulosic feedstock with potential of industrial applications.
authors.affiliation: State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
authors.forename: Hongsen
authors.initials: H
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China. Electronic address: jbao@ecust.edu.cn.
authors.forename: Jie
authors.initials: J
authors.lastname: Bao
mesh_terms: D000143:Acids / Q000378:metabolism*; D001234:Aspergillus niger / Q000378:metabolism*; D019149:Bioreactors; D003890:Desiccation; D005285:Fermentation; D005942:Gluconates / Q000378:metabolism*; D008658:Inactivation, Metabolic; D013213:Starch / Q000378:metabolism; D003313:Zea mays / Q000378:metabolism*
chemical_list: D000143:Acids; D005942:Gluconates; D013213:Starch; C030691:gluconic acid
keywords: Aspergillus niger; Cement additive; Gluconic acid; Inhibitor tolerance; Lignocellulose