title: A Decade-old Change in the Screening Rate for Hepatocellular Carcinoma Among a Hepatitis B Virus-infected Population in Korea.
abstract: BACKGROUND
  Evaluating a change in the screening rate for hepatocellular carcinoma (HCC) is critical for understanding screening implementation, and whether targeted population groups are receiving proper screening. This study examined recent nationwide changes in HCC screening use among hepatitis B virus (HBV)-infected populations after the introduction of the Korean National Cancer Screening Program and predictors of screening adherence.
  
  
  METHODS
  We analyzed 165 and 276 participants ≥40 years of age who were hepatitis B surface antigen-positive from 2001 (14,936 participants) to 2010-2011 (9159 participants) Korea National Health and Nutrition Examination Surveys, respectively. Demographic data, socioeconomic factors, and HCC screening use were collected by means of self-reported questionnaires.
  
  
  RESULTS
  The rate of HCC screening within the previous 2 years increased significantly from 17.5% in 2001 to 40.3% in 2010-2011 (P < 0.0001). The rate of HCC screening use increased from 2001 to 2010-2011 in all study populations. Subjects who had a higher income status and were aware of their infection were more likely to have undergone recent HCC screening.
  
  
  CONCLUSIONS
  This study showed a substantial increase in HCC screening in high-risk HBV-infected subjects from 2001 to 2010-2011. However, the HCC screening participation rate remained suboptimal despite the introduction of the nationwide screening program. Efforts should be made to identify high-risk individuals and increase attendance at HCC screening events among high-risk groups.
authors.forename: Hee Yeon
authors.initials: HY
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Division of Hepatology, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
authors.forename: Chang Wook
authors.initials: CW
authors.lastname: Kim
authors.forename: Jong Young
authors.initials: JY
authors.lastname: Choi
authors.forename: Chung-Hwa
authors.initials: CH
authors.lastname: Park
authors.forename: Chang Don
authors.initials: CD
authors.lastname: Lee
authors.forename: Hyeon Woo
authors.initials: HW
authors.lastname: Yim
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000209:etiology / Q000821:virology; D005260:Female; D006509:Hepatitis B / Q000150:complications*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000821:virology; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D056910:Republic of Korea; D012307:Risk Factors; D011795:Surveys and Questionnaires