title: Risk factors of deep infection in operatively treated pilon fractures (AO/OTA: 43).
abstract: OBJECTIVE
  The purpose of this study is to evaluate risk factors of deep infection following pilon fractures.
  
  
  METHODS
  This investigation was performed after gathering a six-year retrospective database from a single academic trauma center.
  
  
  RESULTS
  These include an overall incidence of deep infection of 16.1% (57/355). Deep infection was diagnosed at an average of 88 days (±64 days) from initial injury with a range of 10-281 days. Development of deep infection occurred in 23.2% (33/142) of open fractures, vs 11.3% (24/213) of closed fractures.
  
  
  CONCLUSIONS
  Open fractures, hypertension and male gender were associated with an increased risk of developing deep infection. In addition, even optimal surgical management may not significantly modify rates of deep surgical site infection.
authors.affiliation: Vanderbilt Department of Orthopaedic Surgery and Rehabilitation, Orthopaedic Trauma Institute, Nashville, TN 37232, United States.
authors.forename: Cesar S
authors.initials: CS
authors.lastname: Molina
authors.affiliation: Vanderbilt Department of Orthopaedic Surgery and Rehabilitation, Orthopaedic Trauma Institute, Nashville, TN 37232, United States.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Stinner
authors.affiliation: Vanderbilt Department of Orthopaedic Surgery and Rehabilitation, Orthopaedic Trauma Institute, Nashville, TN 37232, United States.
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Fras
authors.affiliation: Vanderbilt Department of Orthopaedic Surgery and Rehabilitation, Orthopaedic Trauma Institute, Nashville, TN 37232, United States.
authors.forename: Jason M
authors.initials: JM
authors.lastname: Evans
keywords: Deep infection; Orthopedic trauma; Pilon fracture