title: Renal cell carcinoma with metachronous metastasis to the contralateral adrenal gland and urinary bladder: A case report.
abstract: The adrenal gland and urinary bladder are rare localizations of metastases of renal cell carcinoma (RCC). In the present study, a case of metastasis to the contralateral adrenal gland and urinary bladder of clear cell-type RCC (ccRCC) in the left kidney is reported in a male who had undergone left radical nephrectomy at 55 years of age. Computed tomography (CT) revealed a mass in the right adrenal gland 5 years following surgery, and type-B ultrasound demonstrated a 1.0-cm solid space-occupying lesion in the right wall of the bladder. Consequently, laparoscopic right adrenalectomy and transurethral resection of the bladder tumor were performed. Furthermore, based on histopathological examination and immunohistochemical staining, the patient was pathologically diagnosed with contralateral adrenal gland and urinary bladder metastasis of ccRCC. CT performed at the 1-year follow-up detected multiple solid space-occupying lesions in the right kidney. Therefore, the patient was treated with sunitinib targeted therapy. To date, the patient is generally in good condition, without evident drug side effects or complaints of discomfort.
authors.affiliation: Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang 311202, P.R. China.
authors.forename: Kai
authors.initials: K
authors.lastname: Wang
authors.affiliation: Department of Urology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, P.R. China.
authors.forename: Junkai
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang 311202, P.R. China.
authors.forename: J I
authors.initials: JI
authors.lastname: Sun
authors.affiliation: Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang 311202, P.R. China.
authors.forename: Dachuan
authors.initials: D
authors.lastname: Zhong
authors.affiliation: Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang 311202, P.R. China.
authors.forename: Shengcheng
authors.initials: S
authors.lastname: Tai
authors.affiliation: Department of Urology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai 200003, P.R. China.
authors.forename: Danfeng
authors.initials: D
authors.lastname: Xu
authors.affiliation: Department of Urology, Zhejiang Xiaoshan Hospital, Hangzhou, Zhejiang 311202, P.R. China.
authors.forename: Y I
authors.initials: YI
authors.lastname: Fan
keywords: adrenal gland; adrenalectomy; renal cell carcinoma; urinary bladder