title: Vitamin D levels in white coat and sustained hypertension.
abstract: OBJECTIVE
  The plasma levels of vitamin D in patients with white coat hypertension (WCHT) have not been studied previously. The aim of this study was to evaluate vitamin D levels in WCHT and compare with sustained hypertension (SHT) and with normotension (NT).
  
  
  METHODS
  Fifty-three normotensive, 42 WCHT, and 59 SHT patients were recruited in this study. The participants were matched for age, sex, and BMI. The vitamin D levels were determined using the electrochemiluminescence immunoassay method.
  
  
  RESULTS
  Plasma vitamin D levels were significantly lower in SHT than in the WCHT and NT groups (26.4±4.9, 34.3±3.6, and 36±5 ng/ml, respectively), and were similar in the WCHT and NT groups. There was a negative correlation between vitamin D levels and blood pressure parameters such as clinic systolic blood pressure (SBP), clinic diastolic blood pressure (DBP), 24-h SBP, 24-h DBP, daytime SBP, daytime DBP, night-time SBP, and night-time DBP (r=-0.554, -0.419, -0.629, -0.427, -0.559, -0.534, -0.607, -0.462, respectively, and all P<0.001) in the entire study group. Clinic SBP (B±SE=-0.97±0.037, P=0.009) and 24-h SBP (B±SE=-0.138±0.055, P=0.013) were identified as predictors for vitamin D levels in the entire study group.
  
  
  CONCLUSIONS
  Our data show that sustained hypertensive patients have lower vitamin D levels than white coat hypertensive and normotensive individuals. White coat hypertensive patients without other cardiovascular risk factors have higher vitamin D levels than sustained hypertensive patients, suggesting that they have a lower cardiovascular risk.
authors.affiliation: Departments of aCardiology bStatistics cBiochemistry, Faculty of Medicine, Namik Kemal University, Tekirdag, Turkey.
authors.forename: Seref
authors.initials: S
authors.lastname: Alpsoy
authors.forename: Aydin
authors.initials: A
authors.lastname: Akyüz
authors.forename: Dursun C
authors.initials: DC
authors.lastname: Akkoyun
authors.forename: Demet Ö
authors.initials: DÖ
authors.lastname: Gür
authors.forename: Birol
authors.initials: B
authors.lastname: Topcu
authors.forename: Feti
authors.initials: F
authors.lastname: Tülübas
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014807:Vitamin D / Q000097:blood*; D059466:White Coat Hypertension / Q000097:blood* / Q000503:physiopathology*
chemical_list: D014807:Vitamin D