title: China Patient-centered Evaluative Assessment of Cardiac Events Prospective Study of Acute Myocardial Infarction: Study Design.
abstract: BACKGROUND
  Despite the rapid growth in the incidence of acute myocardial infarction (AMI) in China, there is limited information about patients' experiences after AMI hospitalization, especially on long-term adverse events and patient-reported outcomes (PROs).
  
  
  METHODS
  The China Patient-centered Evaluative Assessment of Cardiac Events (PEACE)-Prospective AMI Study will enroll 4000 consecutive AMI patients from 53 diverse hospitals across China and follow them longitudinally for 12 months to document their treatment, recovery, and outcomes. Details of patients' medical history, treatment, and in-hospital outcomes are abstracted from medical charts. Comprehensive baseline interviews are being conducted to characterize patient demographics, risk factors, presentation, and healthcare utilization. As part of these interviews, validated instruments are administered to measure PROs, including quality of life, symptoms, mood, cognition, and sexual activity. Follow-up interviews, measuring PROs, medication adherence, risk factor control, and collecting hospitalization events are conducted at 1, 6, and 12 months after discharge. Supporting documents for potential outcomes are collected for adjudication by clinicians at the National Coordinating Center. Blood and urine samples are also obtained at baseline, 1- and 12-month follow-up. In addition, we are conducting a survey of participating hospitals to characterize their organizational characteristics.
  
  
  CONCLUSIONS
  The China PEACE-Prospective AMI study will be uniquely positioned to generate new information regarding patient's experiences and outcomes after AMI in China and serve as a foundation for quality improvement activities.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Rachel P
authors.initials: RP
authors.lastname: Dreyer
authors.forename: Xi
authors.initials: X
authors.lastname: Li
authors.forename: Xue
authors.initials: X
authors.lastname: Du
authors.forename: Nicholas S
authors.initials: NS
authors.lastname: Downing
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Hai-Bo
authors.initials: HB
authors.lastname: Zhang
authors.forename: Fang
authors.initials: F
authors.lastname: Feng
authors.forename: Wen-Chi
authors.initials: WC
authors.lastname: Guan
authors.forename: Xiao
authors.initials: X
authors.lastname: Xu
authors.forename: Shu-Xia
authors.initials: SX
authors.lastname: Li
authors.forename: Zhen-Qiu
authors.initials: ZQ
authors.lastname: Lin
authors.forename: Frederick A
authors.initials: FA
authors.lastname: Masoudi
authors.forename: John A
authors.initials: JA
authors.lastname: Spertus
authors.forename: Harlan M
authors.initials: HM
authors.lastname: Krumholz
authors.affiliation: National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Jiang
mesh_terms: D000208:Acute Disease; D000328:Adult; D002681:China; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis*; D018802:Patient-Centered Care; D011446:Prospective Studies; D011788:Quality of Life; D012307:Risk Factors; D055815:Young Adult