title: Antifouling activity of green-synthesized 7-hydroxy-4-methylcoumarin.
abstract: In the search for new environmental-friendly antifoulants for replace metallic biocides, 7-hydroxy-4-methylcoumarin was synthesized according to green chemistry procedures. This compound was characterized by current organic analysis and its antifouling properties were firstly evaluated on the bivalve Mytilus edulis platensis in the laboratory. In the second stage, a soluble matrix antifouling coating formulated with this compound was assayed in marine environment. Laboratory experiments showed that 7-hydroxy-4-methylcoumarin was effective in inhibiting both the settlement as well as the byssogenesis of mussels. In addition, after exposure time in the sea, painted panels containing this compound showed strong antifouling effect on conspicuous species of the fouling community of Mar el Plata harbor. In conclusion, green-synthesized coumarin could be a suitable antifoulant candidate for marine protective coatings.
authors.affiliation: Centro de Investigación y Desarrollo en Tecnología de Pinturas (CIDEPINT), Calle 52 e/ 121 y 122, 1900 La Plata, Argentina; Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata, Calle 60 y 122, 1900 La Plata, Argentina.
authors.forename: Miriam
authors.initials: M
authors.lastname: Pérez
authors.affiliation: Centro de Investigación y Desarrollo en Tecnología de Pinturas (CIDEPINT), Calle 52 e/ 121 y 122, 1900 La Plata, Argentina.
authors.forename: Mónica
authors.initials: M
authors.lastname: García
authors.affiliation: Centro de Investigación en Sanidad Vegetal (CISaV), Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, Calle 60 y 119, 1900 La Plata, Argentina.
authors.forename: Diego
authors.initials: D
authors.lastname: Ruiz
authors.affiliation: Centro de Investigación en Sanidad Vegetal (CISaV), Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, Calle 60 y 119, 1900 La Plata, Argentina.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Autino
authors.affiliation: Centro de Investigación en Sanidad Vegetal (CISaV), Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, Calle 60 y 119, 1900 La Plata, Argentina; Centro de Investigación y Desarrollo en Ciencias Aplicadas (CINDECA), Departamento de Química, Facultad de Ciencias Exactas, UNLP-CCT-CONICET, Calle 47 N °257, 1900 La Plata, Argentina.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Romanelli
authors.affiliation: Centro de Investigación y Desarrollo en Tecnología de Pinturas (CIDEPINT), Calle 52 e/ 121 y 122, 1900 La Plata, Argentina; Centro de Investigación en Sanidad Vegetal (CISaV), Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, Calle 60 y 119, 1900 La Plata, Argentina. Electronic address: antifouling@cidepint.gov.ar.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Blustein
mesh_terms: D000818:Animals; D057219:Biofouling / Q000517:prevention & control*; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D055772:Green Chemistry Technology; D015394:Molecular Structure; D049880:Mytilus edulis / Q000187:drug effects*; D010150:Paint; D013499:Surface Properties
chemical_list: C000611318:7-hydroxy-4-methylcoumarin; D003374:Coumarins
keywords: Biofouling; antifouling coatings; coumarins; green chemistry