title: [Adult medulloblastoma: Retrospective series of 21 patients].
abstract: OBJECTIVE
  Retrospective analysis of the results of 21 adults treated for medulloblastoma.
  
  
  METHODS
  Between 1978 and 2011, 21 adults with an average age of 31 years (18.3-50) were treated with surgery then with radiotherapy (n=20) at the Comprehensive Cancer Center of Strasbourg. For some (n=12), treatment consisted of chemotherapy.
  
  
  RESULTS
  After a mean follow-up of 122 months (19-423), six relapses and seven deaths were observed. Overall survival at 5 years and 10 years was 89.4 ± 7.1% for both. Disease-free survival at 5 years and 10 years was 79.6 ± 9.2% and 85.7 ± 7.6% and 60.6 ± 17.7%, respectively.
  
  
  CONCLUSIONS
  The rarity of medulloblastoma, especially in adults and these results confirm the necessity of international protocols.
authors.affiliation: Département de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67000 Strasbourg, France.
authors.forename: C
authors.initials: C
authors.lastname: Vigneron
authors.affiliation: Département de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67000 Strasbourg, France.
authors.forename: D
authors.initials: D
authors.lastname: Antoni
authors.affiliation: Service de neurochirurgie, CHU Hautepierre, 3, avenue Molière, 67200 Strasbourg, France.
authors.forename: A
authors.initials: A
authors.lastname: Coca
authors.affiliation: Département de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67000 Strasbourg, France.
authors.forename: C
authors.initials: C
authors.lastname: Niederst
authors.affiliation: Département de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67000 Strasbourg, France.
authors.forename: D
authors.initials: D
authors.lastname: Jarnet
authors.affiliation: Département de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67000 Strasbourg, France.
authors.forename: P
authors.initials: P
authors.lastname: Meyer
authors.affiliation: Service de neurochirurgie, CHU Hautepierre, 3, avenue Molière, 67200 Strasbourg, France.
authors.forename: P
authors.initials: P
authors.lastname: Kehrli
authors.affiliation: Département de radiothérapie, centre Paul-Strauss, 3, rue de la Porte-de-l'Hôpital, 67000 Strasbourg, France; Laboratoire EA 3430, fédération de médecine translationnelle de Strasbourg (FMTS), université de Strasbourg, 3, avenue Molière, 67200 Strasbourg, France. Electronic address: gnoel@strasbourg.unicancer.fr.
authors.forename: G
authors.initials: G
authors.lastname: Noël
mesh_terms: D000293:Adolescent; D000328:Adult; D002528:Cerebellar Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy*; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000401:mortality* / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D055815:Young Adult
keywords: Adulte; Adults; Medulloblastoma; Médulloblastome; Radiothérapie