title: A simulation model to study the role of the extracranial venous drainage pathways in intracranial hemodynamics.
abstract: Alterations in the extracranial venous circulation due to posture changes, and/or extracranial venous obstructions in patients with vascular diseases, can have important implications on cerebral hemodynamics. A hemodynamic model for the study of cerebral venous outflow was developed to investigate the correlations between extracranial blood redistributions and changes in the intracranial environment. Flow data obtained with both magnetic resonance (MR) and Echo-Color Doppler (ECD) technique are used to validate the model. The very good agreement between simulated supine and upright flows and experimental results means that the model can correctly reproduce the main factors affecting the extracranial venous circulation.
authors.forename: G
authors.initials: G
authors.lastname: Gadda
authors.forename: A
authors.initials: A
authors.lastname: Taibi
authors.forename: F
authors.initials: F
authors.lastname: Sisini
authors.forename: M
authors.initials: M
authors.lastname: Gambaccini
authors.forename: S K
authors.initials: SK
authors.lastname: Sethi
authors.forename: D
authors.initials: D
authors.lastname: Utriainen
authors.forename: E M
authors.initials: EM
authors.lastname: Haacke
authors.forename: P
authors.initials: P
authors.lastname: Zamboni
authors.forename: M
authors.initials: M
authors.lastname: Ursino
mesh_terms: D000465:Algorithms; D001783:Blood Flow Velocity; D002550:Cerebral Veins / Q000502:physiology*; D002560:Cerebrovascular Circulation; D004322:Drainage; D006801:Humans; D008955:Models, Cardiovascular; D011187:Posture