title: Automatic reactor for solid-phase synthesis of molecularly imprinted polymeric nanoparticles (MIP NPs) in water.
abstract: We report the development of an automated chemical reactor for solid-phase synthesis of MIP NPs in water. Operational parameters are under computer control, requiring minimal operator intervention. In this study, "ready for use" MIP NPs with sub-nanomolar affinity are prepared against pepsin A, trypsin and α-amylase in only 4 hours.
authors.affiliation: Cranfield Health, Cranfield University, Cranfield, MK43 0AL, United Kingdom.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Poma
authors.affiliation: Cranfield Health, Cranfield University, Cranfield, MK43 0AL, United Kingdom.
authors.forename: Antonio
authors.initials: A
authors.lastname: Guerreiro
authors.affiliation: Cranfield Health, Cranfield University, Cranfield, MK43 0AL, United Kingdom.
authors.forename: Sarah
authors.initials: S
authors.lastname: Caygill
authors.affiliation: Cranfield Health, Cranfield University, Cranfield, MK43 0AL, United Kingdom.
authors.forename: Ewa
authors.initials: E
authors.lastname: Moczko
authors.affiliation: Cranfield Health, Cranfield University, Cranfield, MK43 0AL, United Kingdom.
authors.forename: Sergey
authors.initials: S
authors.lastname: Piletsky