title: The Analysis of Mean Platelet Volume and Platelet Distribution Width Levels in Appendicitis.
abstract: We aimed to analyze the diagnostic value of mean platelet volume and platelet distribution width, which are also known as the markers of platelet count, in acute and perforated appendicitis. The data of 202 patients who applied to general surgery clinic in Mustafa Kemal University Hospital from 2007 to 2012 with acute appendicitis were analyzed retrospectively. The findings were separated to two groups due to the perforation status (perforated vs. non-perforated). Age, sex, leukocyte, hemoglobin, hematocrit, mean platelet volume, and platelet distribution width were examined. The mean age of the patients was 35.8. Twenty-one of all cases were perforated appendicitis (10.4 %), and the rest was acute appendicitis (non-perforated) (n = 181, 89.6 %). The mean platelet volume value was 9.8 ± 2.1 fL; mean thrombocyte count, 340.9 × 10(9)/L; and mean platelet distribution width value, 18.3 %. There were statistically significant differences between sex and age, hemoglobin, hematocrit, leukocyte, mean platelet volume, and platelet distribution width. There was a positive correlation between mean platelet volume, platelet distribution width, and platelet. Age, leukocyte, platelet, mean platelet volume, and platelet distribution width were higher in cases with perforation as a comparison with non-perforated cases. We think that mean platelet volume and platelet distribution width may be valuable markers to detect the risk of perforation in early periods of acute appendicitis.
authors.affiliation: Faculty of Medicine, Department of General Surgery, Mustafa Kemal University, 31120 Hatay, Turkey.
authors.forename: Akin
authors.initials: A
authors.lastname: Aydogan
authors.affiliation: Faculty of Medicine, Department of General Surgery, Mustafa Kemal University, 31120 Hatay, Turkey.
authors.forename: Seckin
authors.initials: S
authors.lastname: Akkucuk
authors.affiliation: Faculty of Medicine, Department of Family Medicine, Mustafa Kemal University, Hatay, Turkey.
authors.forename: Secil
authors.initials: S
authors.lastname: Arica
authors.affiliation: Faculty of Medicine, Department of Biochemistry, Mustafa Kemal University, Hatay, Turkey.
authors.forename: Sedat
authors.initials: S
authors.lastname: Motor
authors.affiliation: Faculty of Medicine, Department of Emergency Medicine, Mustafa Kemal University, Hatay, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Karakus
authors.affiliation: Faculty of Medicine, Department of General Surgery, Sakarya University, Sakarya, Turkey.
authors.forename: Orhan Veli
authors.initials: OV
authors.lastname: Ozkan
authors.affiliation: Faculty of Medicine, Department of General Surgery, Mustafa Kemal University, 31120 Hatay, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Yetim
authors.affiliation: Faculty of Medicine, Department of General Surgery, Mustafa Kemal University, 31120 Hatay, Turkey.
authors.forename: Muhyittin
authors.initials: M
authors.lastname: Temiz
keywords: Acute appendicitis; Complete blood count; Mean platelet volume; Perforated appendicitis; Platelet distribution width