title: Synthesis and Herbicidal Activity of 5-Heterocycloxy-3-methyl-1-substituted-1H-pyrazoles.
abstract: With the objective of finding valuable herbicidal candidates, a series of new 5-heterocycloxy-3-methyl-1-substituted-1H-pyrazoles were synthesized and their herbicidal activities were evaluated. The bioassay results showed that some compounds exhibited excellent herbicidal activities at the concentration of 100 mg/L, and compound 5-chloro-2-((3-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-5-yl)oxy)pyrimidine showed bleaching activity to green weeds. In greenhouse conditions, this compound also showed excellent post-emergence herbicidal effect against Digitaria sanguinalis L. at the dosage of 750 g a. i. ha(-1).
authors.affiliation: Department of Applied Chemistry, College of Science, Huazhong Agricultural University, Wuhan 430070, China. kangjing@webmail.hzau.edu.cn.
authors.forename: Jing
authors.initials: J
authors.lastname: Kang
authors.affiliation: Department of Applied Chemistry, College of Science, Huazhong Agricultural University, Wuhan 430070, China. yxl@mail.hzau.edu.cn.
authors.forename: Xia Li
authors.initials: XL
authors.lastname: Yue
authors.affiliation: Department of Applied Chemistry, College of Science, Huazhong Agricultural University, Wuhan 430070, China. chenchang@mail.hzau.edu.cn.
authors.forename: Chang Shui
authors.initials: CS
authors.lastname: Chen
authors.affiliation: Department of Plant Protection, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. jianhl@mail.hzau.edu.cn.
authors.forename: Jian Hong
authors.initials: JH
authors.lastname: Li
authors.affiliation: Department of Plant Protection, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China. mahongju@mail.hzau.edu.cn.
authors.forename: Hong Ju
authors.initials: HJ
authors.lastname: Ma
mesh_terms: D006540:Herbicides / Q000138:chemical synthesis* / Q000494:pharmacology; D015394:Molecular Structure; D057685:Plant Weeds / Q000187:drug effects*; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D006540:Herbicides; D011720:Pyrazoles
keywords: herbicidal activities; pyrazole; synthesis