title: What is prenatal screening and why to do it?
abstract: Patients and providers are faced with a wide array of choices to screen for structural abnormalities, aneuploidy, and genetic diseases in the prenatal period. It is important to consider the features of the diseases being screened for, the characteristics of the screening tests used, and the population being screened when evaluating prenatal screening techniques.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Washington University in St. Louis, St. Louis, MO. Electronic address: temmingl@wudosis.wustl.edu.
authors.forename: Lorene A
authors.initials: LA
authors.lastname: Temming
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Washington University in St. Louis, St. Louis, MO.
authors.forename: George A
authors.initials: GA
authors.lastname: Macones
mesh_terms: D000649:Amniocentesis; D000782:Aneuploidy; D015193:Chorionic Villi Sampling; D025063:Chromosome Disorders / Q000175:diagnosis*; D000013:Congenital Abnormalities / Q000175:diagnosis*; D004247:DNA / Q000097:blood; D005260:Female; D005333:Fetus; D005820:Genetic Testing / Q000379:methods; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D016216:Ultrasonography, Prenatal
chemical_list: D004247:DNA
keywords: Aneuploidy screening; Genetic screening; Prenatal screening