title: Fibroblasts Enhance Migration of Human Lung Cancer Cells in a Paper-Based Coculture System.
abstract: A multilayered paper-based platform is used to investigate the interactions between human lung tumor cells and fibroblasts that are isolated from primary patient tumor samples.
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA.
authors.forename: Gulden
authors.initials: G
authors.lastname: Camci-Unal
authors.affiliation: Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA.
authors.forename: David
authors.initials: D
authors.lastname: Newsome
authors.affiliation: Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA.
authors.forename: Brenda K
authors.initials: BK
authors.lastname: Eustace
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA.|Wyss Institute for Biologically Inspired Engineering, Harvard University, 60 Oxford Street, Cambridge, MA, 02138, USA.
authors.forename: George M
authors.initials: GM
authors.lastname: Whitesides
mesh_terms: D045744:Cell Line, Tumor; D002465:Cell Movement; D018920:Coculture Techniques; D004797:Enzyme-Linked Immunosorbent Assay; D058750:Epithelial-Mesenchymal Transition; D005347:Fibroblasts / Q000166:cytology* / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology; D008856:Microscopy, Fluorescence; D010209:Paper; D016212:Transforming Growth Factor beta / Q000032:analysis
chemical_list: D016212:Transforming Growth Factor beta
keywords: coculture; fibroblasts; migration; tumor cells