title: Electrical resonance with voltage-gated ion channels: perspectives from biophysical mechanisms and neural electrophysiology.
abstract: Electrical resonance, providing selective signal amplification at preferred frequencies, is a unique phenomenon of excitable membranes, which has been observed in the nervous system at the cellular, circuit and system levels. The mechanisms underlying electrical resonance have not been fully elucidated. Prevailing hypotheses attribute the resonance to voltage-gated ion channels on the membrane of single neurons. In this review, we follow this line of thinking to summarize and analyze the biophysical/molecular mechanisms, and also the physiological relevance of channel-mediated electrical resonance.
authors.affiliation: X-Lab for Transmembrane Signaling Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Ge
authors.affiliation: X-Lab for Transmembrane Signaling Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.|School of Life Sciences, Tsinghua University, Beijing 100084, China.|IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
authors.forename: Xiao-dong
authors.initials: XD
authors.lastname: Liu
mesh_terms: D000818:Animals; D055592:Biophysical Phenomena; D055724:Electrophysiological Phenomena; D006801:Humans; D015640:Ion Channel Gating; D007473:Ion Channels / Q000502:physiology*; D009424:Nervous System Physiological Phenomena; D009474:Neurons / Q000502:physiology
chemical_list: D007473:Ion Channels