title: Diabetic foot prevention: the role of exercise therapy in the treatment of limited joint mobility, muscle weakness and reduced gait speed.
abstract: OBJECTIVE
  It is well known that limited joint mobility of the ankle and foot level, impaired muscular performance and reduced gait speed are risk factors for ulceration in diabetic foot. The aim of this study was to evaluate the effect of an experimental protocol of exercise therapy on joint mobility, muscular strength and gait speed in a group of long-term diabetic subjects.
  
  
  METHODS
  The protocol consisted of a 12-week supervised training program; both joint mobility and muscular strength at the ankle were measured before and after exercise therapy respectively by an inclinometer and isometric dynamometers in 26 diabetic subjects and compared to 17 healthy controls.
  
  
  RESULTS
  Ankle joint mobility of plantar flexion was reduced about 36% and dorsal flexion by about 23% in diabetic subjects compared to controls (p < 0.001), but significantly increased after exercise therapy (p < 0.001 for both). Ankle muscular strength in plantar flexion was reduced by about 51% and in dorsal flexion by 30% in diabetic patients compared to controls, but these also significantly increased after exercise therapy (p < 0.001). Consequently, patients' walking speed increased after exercise therapy by 0.28 m/s (p < 0.001).
  
  
  CONCLUSIONS
  A 12-week supervised program of exercise therapy significantly improves joint mobility, muscular performance and walking speed in diabetic patients--thus limiting one of the pathogenic factors of diabetic foot and potentially preventing disability.
authors.forename: Piergiorgio
authors.initials: P
authors.lastname: Francia
authors.forename: Roberto
authors.initials: R
authors.lastname: Anichini
authors.forename: Alessandra
authors.initials: A
authors.lastname: De Bellis
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Seghieri
authors.forename: Renzo
authors.initials: R
authors.lastname: Lazzeri
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Paternostro
authors.forename: Massimo
authors.initials: M
authors.lastname: Gulisano
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D017719:Diabetic Foot / Q000503:physiopathology / Q000517:prevention & control*; D005081:Exercise Therapy; D005260:Female; D005684:Gait; D006801:Humans; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness; D016059:Range of Motion, Articular