title: Insights into acute myeloid leukemia via single cell network profiling.
abstract: Single Cell Network Profiling (SCNP) uses multi-parameter flow cytometry to simultaneously measure resting and evoked intracellular signalling molecules and pathways in distinct cell subsets within a complex tissue sample. This review focuses on the utility of SCNP and its potential applications for chemotherapy selection in Acute Myeloid Leukemia (AML).
authors.affiliation: MD Anderson Cancer Center, University of Texas, 1515 Holcombe Blvd, Box 448, Houston, TX 77030-4095, USA.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Kornblau
authors.affiliation: Dept of Medical Onc/Hem, Princess Margaret Hospital, 610 Univ. Ave. Rm 5-126, Toronto, ON M5G 2M9, Canada.
authors.forename: Mark D
authors.initials: MD
authors.lastname: Minden
authors.affiliation: BC Cancer Research Center, 675 W. 10th Ave, Vancouver, BC V5Z 1L3, Canada.
authors.forename: Donna
authors.initials: D
authors.lastname: Hogge
authors.affiliation: Nodality, 201 Gateway Blvd, South San Francisco, CA 94080, USA.
authors.forename: AileenC
authors.initials: A
authors.lastname: Cohen
authors.affiliation: 201 Gateway Blvd., South San Francisco, CA 94080, USA.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Cesano