title: [Prenatal diagnosis of fetal gray matter heteropia in one case and literature review].
abstract: OBJECTIVE
  To investigate the prenatal ultrasonic manifestations of fetal gray matter heterotopias (FGMH) and evaluate the optimal method its prenatal diagnosis.
  
  
  METHODS
  The prenatal and postnatal ultrasound images and MRI images were analyzed for a fetus with a definitive diagnosis of FGMH. The detection rates of FGMH by prenatal ultrasound and MRI reported in literature were compared.
  
  
  RESULTS
  We identified 11 reports of FGMH from 1998 to 2015, involving 43 cases with prenatal diagnoses. Of the total of 44 cases (including our case), 32 that had been confirmed postpartum had prenatal ultrasound and MRI data, which showed a significantly lower detection rates of FGMH by prenatal ultrasound than by MRI (43.8% vs 93.8%, P<0.001).
  
  
  CONCLUSIONS
  Prenatal ultrasound can only detect subependymal heterotopia with characteristic manifestations, and the detection of other types of FGMH relies on MRI, which is currently the best option for prenatal diagnosis of FGMH.
authors.affiliation: Department of Ultrasound, Shenzhen Maternity Child Healthcare Hospital Affiliated to Southern Medical University, Shenzhen 518028, China. E-mail: delicatezhang@126.com.
authors.forename: Kui
authors.initials: K
authors.lastname: Zhagn
authors.forename: Shengli
authors.initials: S
authors.lastname: Li
authors.forename: Huaxuan
authors.initials: H
authors.lastname: Wen
authors.forename: Ying
authors.initials: Y
authors.lastname: Yuan
mesh_terms: D054221:Classical Lissencephalies and Subcortical Band Heterotopias / Q000175:diagnosis*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005333:Fetus; D066128:Gray Matter / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011296:Prenatal Diagnosis; D016216:Ultrasonography, Prenatal