title: Isolated cutaneous involvement in a child with nodal anaplastic large cell lymphoma.
abstract: Non-Hodgkin lymphoma is a common childhood T-cell and B-cell neoplasm that originates primarily from lymphoid tissue. Cutaneous involvement can be in the form of a primary extranodal lymphoma, or secondary to metastasis from a non-cutaneous location. The latter is uncommon, and isolated cutaneous involvement is rarely reported. We report a case of isolated secondary cutaneous involvement from nodal anaplastic large cell lymphoma (CD30 + and ALK +) in a 7-year-old boy who was on chemotherapy. This case is reported for its unusual clinical presentation as an acute febrile, generalized papulonodular eruption that mimicked deep fungal infection, with the absence of other foci of systemic metastasis.
authors.forename: Vibhu
authors.initials: V
authors.lastname: Mendiratta
authors.forename: Nikita
authors.initials: N
authors.lastname: Gandhi
authors.affiliation: Department of Dermatology, Lady Hardinge Medical College, New Delhi, India.
authors.forename: Shiwangi
authors.initials: S
authors.lastname: Rana
authors.forename: Shailaja
authors.initials: S
authors.lastname: Shukla
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage; D015251:Epirubicin / Q000008:administration & dosage / Q000031:analogs & derivatives; D005500:Follow-Up Studies; D006801:Humans; D017728:Lymphoma, Large-Cell, Anaplastic / Q000188:drug therapy* / Q000473:pathology*; D008297:Male; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011239:Prednisolone / Q000008:administration & dosage; D035583:Rare Diseases; D018570:Risk Assessment; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary*; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D015251:Epirubicin; D014750:Vincristine; C042907:3'-deamino-3'-hydroxydoxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone