title: Long-term survival in women with borderline ovarian tumors: a population-based survey of borderline ovarian tumors in Sweden 1960-2007.
abstract: BACKGROUND
  We conducted an evaluation of incidence and survival of women with borderline ovarian tumors in Sweden.
  
  
  METHODS
  All women diagnosed with borderline ovarian tumor in the Swedish Cancer Register 1960-2007 (n = 6252) combined with follow up in the Swedish Death Registry to 1 July 2009 were included. Estimation of age-standardized relative survival rate according to time periods for diagnosis.
  
  
  RESULTS
  The incidence of borderline ovarian tumors increased during the study period, with a steep increase during the 1980s. The age standardized 5-year relative survival including all borderline tumors diagnosed 2000-07 was 97% (95% CI 92-99%). In women aged ≤64 years, the 10-year relative survival related to age at diagnosis of borderline tumors ranged from 95 to 98% and was 89% in women aged 65-74 years. In a multivariable analysis including age and decade of diagnosis relative survival for every decade increased. The 10-year relative survival in women with mucinous and serous borderline tumors did not differ significantly (p = 0.121).
  
  
  CONCLUSIONS
  Results of the present study are reassuring about long-term survival in women with borderline ovarian tumors. The age-standardized relative survival rate increased across time periods for diagnosis. There was no difference in long-term survival between mucinous and serous borderline ovarian tumors.
authors.affiliation: Department of Obstetrics & Gynecology, Skanes University Hospital, Lund, Sweden.
authors.forename: Grigorios
authors.identifier: http://orcid.org/0000-0003-1657-7704
authors.initials: G
authors.lastname: Kalapotharakos
authors.affiliation: Department of Cancer Epidemiology, Skanes University Hospital, Lund, Sweden.
authors.forename: Thomas
authors.identifier: http://orcid.org/0000-0003-0236-3692
authors.initials: T
authors.lastname: Högberg
authors.affiliation: Regional Cancer Center, Stockholm, Sweden.
authors.forename: Kjell
authors.identifier: http://orcid.org/0000-0001-8505-6326
authors.initials: K
authors.lastname: Bergfeldt
authors.affiliation: Department of Obstetrics & Gynecology, Skanes University Hospital, Lund, Sweden.
authors.forename: Christer
authors.identifier: http://orcid.org/0000-0003-2267-8325
authors.initials: C
authors.lastname: Borgfeldt
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D011230:Precancerous Conditions / Q000453:epidemiology; D012042:Registries; D015996:Survival Rate; D013548:Sweden / Q000453:epidemiology
keywords: Borderline ovarian tumors; cancer registry; long-term follow-up; population-based; relative survival