title: [Instructions for aggregated evidence: Systematic reviews and meta-analyses (part 1)].
abstract: High-quality, up-to-date, systematic reviews comprehensively summarize the evidence from clinical studies for a focused clinical question. A meta-analyses is a quantitative summary of results from individual studies and often part of a systematic review. Important features of a systematic review are a focused research question, a comprehensive, reproducible search for primary studies, selection of studies using clear and transparent eligibility criteria, and a standardized critical appraisal of the methodological quality of included studies.
authors.forename: Birgit
authors.initials: B
authors.lastname: Schindler
authors.forename: Matthias
authors.initials: M
authors.lastname: Briel
authors.forename: Judith
authors.initials: J
authors.lastname: Günther
mesh_terms: D035843:Biomedical Research; D019317:Evidence-Based Medicine; D006801:Humans; D015201:Meta-Analysis as Topic; D012196:Review Literature as Topic