title: Assessment of adherence to cardiovascular medicines in rural population: An observational study in patients attending a tertiary care hospital.
abstract: BACKGROUND
  Nonadherence to cardiovascular medicines is a major concern. It increases the morbidity and mortality of cardiovascular patients. The work was conducted to evaluate the adherence to cardiovascular medicines in patients of rural India.
  
  
  METHODS
  The study was conducted in the Department of Medicine involving rural patients with essential hypertension (HTN), congestive cardiac failure (CCF), and ischemic heart disease (IHD) over 12 months period. Patients were prescribed with cardiovascular medicines at the initial visit and adherence to medicines was assessed in the subsequent visit. Four items Morisky's Medication Adherence Scale (MMAS-4) was used for assessing medication adherence. Patients were considered adherent to medication if they answered negatively to all four questions.
  
  
  RESULTS
  Overall adherence to medication was 20.83%, 28.37% and 32% in HTN, CCF, and IHD patients, respectively. Nonadherence was highest in patients of HTN. Among the four reasons of nonadherence assessed by MMAS-4, carelessness was the most common and forgetfulness was the least common cause of nonadherence in all the three groups of patients.
  
  
  CONCLUSIONS
  Patients of rural India adhere poorly to cardiovascular medicines. Nonadherence should be considered as a public health problem. Strategies for detecting the level of adherence of cardiovascular medicines, its barriers, and subsequent interventions should be developed by policy-makers to reduce morbidity and mortality due to cardiovascular disorders.
authors.affiliation: Department of Medicine, Midnapore Medical College, Paschim Medinipur, West Bengal, India.
authors.forename: Gouranga
authors.initials: G
authors.lastname: Santra
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001294:Attitude to Health; D002316:Cardiotonic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006333:Heart Failure / Q000188:drug therapy*; D006784:Hospitals, Teaching; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007194:India; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy*; D012423:Rural Health; D062606:Tertiary Care Centers; D055815:Young Adult
chemical_list: D000959:Antihypertensive Agents; D002316:Cardiotonic Agents
keywords: Cardiovascular medicines; congestive cardiac failure; essential hypertension; ischemic heart disease