title: P300 latency Jitter occurrence in patients with disorders of consciousness: Toward a better design for Brain Computer Interface applications.
abstract: In this study the P300 latency jitter has been explored in an EEG data set collected from a group of patients with disorders of consciousness (DOC; n=13) that was administered with an auditory Oddball paradigm under passive and active conditions. A method based on wavelet transform was applied to estimate single trial P300 waveforms. Preliminary results showed that 5 Vegetative State (VS) and 8 Minimally Conscious Staten (MCS) patients exhibited significantly higher values of P300 latency jitter as compared to those obtained from a control group of 12 healthy subjects. In addition, the magnitude of the P300 latency jitter negatively correlated with patients' clinical status. The existence of such phenomenon might substantially limit an effective use of Brain Computer Interface systems for communication.
authors.forename: Francesca
authors.initials: F
authors.lastname: Schettini
authors.forename: Monica
authors.initials: M
authors.lastname: Risetti
authors.forename: Pietro
authors.initials: P
authors.lastname: Arico
authors.forename: Rita
authors.initials: R
authors.lastname: Formisano
authors.forename: Fabio
authors.initials: F
authors.lastname: Babiloni
authors.forename: Donatella
authors.initials: D
authors.lastname: Mattia
authors.forename: Febo
authors.initials: F
authors.lastname: Cincotti
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D062207:Brain-Computer Interfaces; D016022:Case-Control Studies; D003244:Consciousness Disorders / Q000503:physiopathology*; D004569:Electroencephalography / Q000379:methods*; D004585:Electrooculography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018458:Persistent Vegetative State / Q000503:physiopathology; D012815:Signal Processing, Computer-Assisted; D058067:Wavelet Analysis