title: Fibromyxoid nephrogenic adenoma protruding in a renal cortical cyst. A rare morphological variant in an outstanding location.
abstract: Nephrogenic adenoma (NA) is an unusual, benign lesion of the urinary tract, generally presenting in the bladder and with less frequency in the renal pelvis, urethra or ureter. It consists of tubules, microcysts and papillae lined by a single layer of low cuboidal epithelium without atypia. Recently, a fibromyxoid variant mimicking an infiltrating mucinous adenocarcinoma has been described. We report hereby the case of a 70-year-old female with a fibromixoid NA protruding in a renal cortical cyst. Only one case of NA in a renal cortical cyst has been found in the literature and it was of the classical type. The development of a NA in a renal cortical cyst lends support to the theory that the NA results from proliferation of secondarily implanted exfoliated renal epithelial cells.
authors.affiliation: Department of Pathology, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain. Electronic address: radia.khedaoui@salud.madrid.org.
authors.forename: Radia
authors.initials: R
authors.lastname: Khedaoui
authors.affiliation: Department of Pathology, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Encabo
authors.affiliation: Department of Pathology, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Tardío
mesh_terms: D000236:Adenoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007672:Kidney Cortex / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D052177:Kidney Diseases, Cystic / Q000473:pathology* / Q000601:surgery; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D010535:Laparoscopy; D009392:Nephrectomy / Q000379:methods; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor
keywords: Fibromyxoid nephrogenic adenoma; Nephrogenic adenoma; Renal cortical cyst; Renal tumor