title: Emergence of critical dynamics in large-scale in vitro cortical networks.
abstract: In vitro neuronal networks coupled to Micro-Electrode Arrays (MEAs) represent a valid experimental framework to study neuronal dynamics. This preparation is free of chemical or physical constraints and allows neurons to self-organize during development, creating networks that exhibit complex spatio-temporal patterns of activity. Starting from this experimental evidence, here we address the question whether a particular network architecture can drive the network dynamics towards a sub-, super-, or critical state.
authors.forename: Paolo
authors.initials: P
authors.lastname: Massobrio
authors.forename: Valentina
authors.initials: V
authors.lastname: Pasquale
authors.forename: Sergio
authors.initials: S
authors.lastname: Martinoia
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology / Q000196:embryology; D003198:Computer Simulation; D008839:Microelectrodes; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D017207:Rats, Sprague-Dawley