title: The current epidemiological status of infectious coryza and efficacy of PoulShot Coryza in specific pathogen-free chickens.
abstract: Infectious coryza (IC) is an infectious disease caused by Avibacterium (Av.) paragallinarum. IC is known to cause economic losses in the poultry industry via decreased egg production in layers. Between 2012 and 2013, Av. paragallinarum was isolated from seven chicken farms by Chungbuk National University. We identified Av. paragallinarum, the causative pathogen of IC by polymerase chain reaction (PCR) and serovar serotype A, by multiplex PCR. Antibiotic sensitivity tests indicated that a few field-isolated strains showed susceptibility to erythromycin, gentamicin, lincomycin, neomycin, oxytetracycline, spectinomycin, and tylosin. A serological survey was conducted to evaluate the number of flocks that were positive for Av. paragallinarum by utilizing a HI test to determine the existence of serovar A. Serological surveys revealed high positivity rates of 86.4% in 2009, 78.9% in 2010, 70.0% in 2011, and 69.6% in 2012. We also challenged specific pathogen-free chickens with isolated domestic strains, ADL121286 and ADL121500, according to the measured efficacy of the commercial IC vaccine, PoulShot Coryza. We confirmed the effectiveness of the vaccine based on relief of clinical signs and a decreased re-isolation rate of ADL121500 strain. Our results indicate IC is currently prevalent in Korea, and that the commercial vaccine is effective at protecting against field strains.
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Moo-Sung
authors.initials: MS
authors.lastname: Han
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Jong-Nyeo
authors.initials: JN
authors.lastname: Kim
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Eun-Ok
authors.initials: EO
authors.lastname: Jeon
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Hae-Rim
authors.initials: HR
authors.lastname: Lee
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Bon-Sang
authors.initials: BS
authors.lastname: Koo
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Kyeong-Cheol
authors.initials: KC
authors.lastname: Min
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Seung-Baek
authors.initials: SB
authors.lastname: Lee
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Yeon-Ji
authors.initials: YJ
authors.lastname: Bae
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Jong-Suk
authors.initials: JS
authors.lastname: Mo
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: Sun-Hyung
authors.initials: SH
authors.lastname: Cho
authors.affiliation: Department of Veterinary Preventive Medicine, College of Veterinary Medicine, Ohio State University, Wooster, OH 44691, USA.
authors.forename: Hye-Sun
authors.initials: HS
authors.lastname: Jang
authors.affiliation: Avian Disease Laboratory, College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
authors.forename: In-Pil
authors.initials: IP
authors.lastname: Mo
mesh_terms: D000818:Animals; D002645:Chickens; D006192:Haemophilus Infections / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary* / Q000821:virology; D044134:Haemophilus paragallinarum / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011201:Poultry Diseases / Q000453:epidemiology* / Q000517:prevention & control / Q000821:virology; D056910:Republic of Korea / Q000453:epidemiology; D017422:Sequence Analysis, DNA / Q000662:veterinary; D013047:Specific Pathogen-Free Organisms; D014765:Viral Vaccines / Q000494:pharmacology*
chemical_list: D014765:Viral Vaccines
keywords: Avibacterium paragallinarum; infectious coryza; infectious coryza vaccine; serologic survey