title: Bioelectrocatalytic systems for health applications.
abstract: We present a brief overview of bioelectrocatalytic devices for in vitro health applications, including food safety and environmental analysis, focusing on microelectrode- and microfluidic-based biosensors, paper-based point-of-care devices and wearable biosensors. The main hurdles and future perspectives are discussed. We then consider the role of electron transfer between a biocatalyst and an electrode in biosensor design. Brief descriptions of indirect, direct and mediated mechanisms are given. The principal strategies, as well as recent developments for modulation of electron transfer in biocatalytic systems are summarised. In conclusion, we highlight some of the challenges associated with improving these redox systems.
authors.affiliation: Department of Physics, Chemistry and Biology, Linköping University, SE-581 83 Linköping, Sweden.
authors.forename: Alina N
authors.initials: AN
authors.lastname: Sekretaryova
authors.affiliation: Department of Physics, Chemistry and Biology, Linköping University, SE-581 83 Linköping, Sweden.
authors.forename: Mats
authors.initials: M
authors.lastname: Eriksson
authors.affiliation: Department of Physics, Chemistry and Biology, Linköping University, SE-581 83 Linköping, Sweden. Electronic address: anthony.turner@liu.se.
authors.forename: Anthony P F
authors.initials: AP
authors.lastname: Turner
mesh_terms: D055162:Biocatalysis; D015374:Biosensing Techniques; D004579:Electron Transport; D006801:Humans; D066298:In Vitro Techniques; D008839:Microelectrodes
keywords: Direct electron transfer; Immobilisation; Mediated electron transfer; Microbiosensor; Nanobiosensor; Paper-based biosensor; Self-powered biosensor; Wearable biosensor