title: A Facile Method for the One-Step Synthesis of Hydrophilic Up-Conversion Nanoparticles.
abstract: Up-conversion nanoparticles made from NaYF4:Yb3+, Er3+ have been used as imaging materials in many studies. These stable luminescence materials always needs hydrophilic modification to meet the challenges in biomedical applications. In our work, hydrophilic up-conversion nanoparticles (HUNPs) with stable luminescence character were prepared by a one-step method. The excitation wavelength of this type of nanoparticles is 980 nm. Furthermore, from the data of zeta potential measurement and energy dispersive X-ray (EDX) analysis, we deduced that these nanoparticles exhibited amino groups on the surface. MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide) study showed that the as-prepared up-conversion nanoparticles demonstrated low cytotoxicity and excellent biocompatibility.
authors.forename: Ting
authors.initials: T
authors.lastname: Wang
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.forename: Liming
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhuoxuan
authors.initials: Z
authors.lastname: Lu
authors.forename: Lingling
authors.initials: L
authors.lastname: Guo
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.forename: Zhifei
authors.initials: Z
authors.lastname: Wang
authors.forename: Zhan
authors.initials: Z
authors.lastname: Chen
authors.forename: Nongyue
authors.initials: N
authors.lastname: He
authors.forename: Changren
authors.initials: C
authors.lastname: Zhou
authors.forename: Li
authors.initials: L
authors.lastname: Huang