title: History and trends of bioactive glass-ceramics.
abstract: The interest around bioactive glass-ceramics (GCs) has grown significantly over the last two decades due to their appropriate biochemical and mechanical properties. The intense research effort in this field has led to some new commercial products for biomedical applications. This review article begins with the basic concepts of GC processing and development via controlled heat treatments of monolithic pieces or sinter-crystallization of powdered glasses. We then go on to describe the processing, properties, and applications of some commercial bioactive GCs and discuss selected valuable reported researches on several promising types of bioactive GCs. The article finishes with a section on open relevant research directions for bioactive GC development.
authors.affiliation: Department of Materials Engineering (DEMa), Center for Research, Technology and Education in Vitreous Materials (CeRTEV), Federal University of São Carlos (UFSCar), São Carlos, SP, 13.565-905, Brazil.
authors.forename: Maziar
authors.initials: M
authors.lastname: Montazerian
authors.affiliation: Department of Materials Engineering (DEMa), Center for Research, Technology and Education in Vitreous Materials (CeRTEV), Federal University of São Carlos (UFSCar), São Carlos, SP, 13.565-905, Brazil.
authors.forename: Edgar
authors.initials: E
authors.lastname: Dutra Zanotto
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000378:metabolism; D002516:Ceramics / Q000737:chemistry* / Q000378:metabolism; D005898:Glass / Q000737:chemistry; D006801:Humans; D006882:Hydroxyapatites / Q000737:chemistry / Q000378:metabolism; D008422:Materials Testing; D019736:Prostheses and Implants; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; C022107:Bioglass; C067324:Bioverit; D006882:Hydroxyapatites; C000593119:cerabone; C120461:sodium oxide-calcium oxide-silicon dioxide-diphosphorus pentoxide; C031323:bio-vitroceramic AP40; C023506:Glass ceramics
keywords: bioactive; biomedical; glass-ceramic; mechanical properties