title: Workshop report: Schistosomiasis vaccine clinical development and product characteristics.
abstract: A schistosomiasis vaccine meeting was organized to evaluate the utility of a vaccine in public health programs, to discuss clinical development paths, and to define basic product characteristics for desirable vaccines to be used in the context of schistosomiasis control and elimination programs. It was concluded that clinical evaluation of a schistosomiasis vaccine is feasible with appropriate trial design and tools. Some basic Preferred Product Characteristics (PPC) for a human schistosomiasis vaccine and for a veterinary vaccine for bovine use were also proposed.
authors.affiliation: Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA. Electronic address: annie.mo@nih.gov.
authors.forename: Annie X
authors.initials: AX
authors.lastname: Mo
authors.affiliation: Center for Tropical and Emerging Global Diseases and the Department of Microbiology, University of Georgia, Athens, GA, USA.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Colley
mesh_terms: D000818:Animals; D002417:Cattle; D002986:Clinical Trials as Topic; D003226:Congresses as Topic; D014943:Global Health; D006801:Humans; D012107:Research Design; D012547:Schistosoma; D012552:Schistosomiasis / Q000517:prevention & control*; D014612:Vaccines / Q000627:therapeutic use*
chemical_list: D014612:Vaccines
keywords: Clinical development plan (CDP); Preferred product characteristics (PPC); Schistosomiasis; Target product profile (TPP); Vaccine