title: Stabilisation of premature infants in the delivery room with nasal high flow.
abstract: OBJECTIVE
  This was a pilot study to determine the feasibility of using nasal high flow (nHF) (also known as heated humidified high-flow nasal cannula) for stabilisation of babies born at <30 weeks gestation in the delivery room (DR) and transfer to the neonatal intensive care unit (NICU).
  
  
  METHODS
  Observational study.
  
  
  METHODS
  Single-centre NICU.
  
  
  METHODS
  Infants born at <30 weeks gestation.
  
  
  METHODS
  Stabilisation and transfer to NICU using nHF.
  
  
  METHODS
  Feasibility of stabilisation as defined by successful transfer and clinical measures of stability at admission to NICU including oxygen requirement, temperature, requirement for surfactant and inotrope use within 72 h of delivery.
  
  
  RESULTS
  Twenty-eight babies were enrolled after written parental consent had been obtained. 25/28 were successfully stabilised in the DR and transferred to the NICU on nHF. The average admission temperature for babies transferred on nHF was 36.9°C and the average inspired oxygen at admission was 29%. Less than half (48%) required surfactant and 60% were still on nHF 72 h after admission. 1 baby received inotropes.
  
  
  CONCLUSIONS
  Our study suggests that using nHF for stabilisation of premature infants in the DR and subsequent transfer to NICU is feasible.
  
  
  BACKGROUND
  NCT01991886.
authors.affiliation: Neonatal Intensive Care Unit, St. Peter's Hospital, Ashford and St. Peter's Hospitals NHS Foundation Trust, Chertsey, UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Reynolds
authors.affiliation: Neonatal Intensive Care Unit, St. Peter's Hospital, Ashford and St. Peter's Hospitals NHS Foundation Trust, Chertsey, UK.
authors.forename: Stamatina
authors.initials: S
authors.lastname: Leontiadi
authors.affiliation: Neonatal Intensive Care Unit, St. Peter's Hospital, Ashford and St. Peter's Hospitals NHS Foundation Trust, Chertsey, UK.
authors.forename: Tracy
authors.initials: T
authors.lastname: Lawson
authors.affiliation: Neonatal Intensive Care Unit, St. Peter's Hospital, Ashford and St. Peter's Hospitals NHS Foundation Trust, Chertsey, UK.
authors.forename: Tosin
authors.initials: T
authors.lastname: Otunla
authors.affiliation: Neonatal Intensive Care Unit, St. Peter's Hospital, Ashford and St. Peter's Hospitals NHS Foundation Trust, Chertsey, UK.
authors.forename: Olayinka
authors.initials: O
authors.lastname: Ejiwumi
authors.affiliation: Neonatal Intensive Care Unit, St. Peter's Hospital, Ashford and St. Peter's Hospitals NHS Foundation Trust, Chertsey, UK.
authors.forename: Nicola
authors.initials: N
authors.lastname: Holland
mesh_terms: D057186:Comparative Effectiveness Research; D045422:Continuous Positive Airway Pressure / Q000379:methods; D003696:Delivery Rooms / Q000706:statistics & numerical data; D005240:Feasibility Studies; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D017063:Outcome Assessment, Health Care; D011663:Pulmonary Surfactants / Q000627:therapeutic use; D012121:Respiration, Artificial / Q000295:instrumentation / Q000379:methods; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*
chemical_list: D011663:Pulmonary Surfactants
keywords: HHHFNC; Neonatology; Respiratory; Resuscitation