title: LncRNA MIAT: Myocardial infarction associated and more.
abstract: Non-coding RNAs are emerging as regulatory RNAs that participate in the regulation of gene expression and play vital roles in various biological and pathological processes. Long non-coding (lncRNA) is a novel class of non-coding RNAs that regulates gene expression by binding to chromatin regulators and interfering RNAs to affect cellular response. Myocardial infarction associated transcript (MIAT) is identified as lncRNAs, which is involved in various diseases, pathological and physiological processes, such as myocardial infarction, diabetic retinopathy, paranoid schizophrenia, microvascular dysfunction and formation of nuclear bodies, and neurogenic commitment. Here we review the growing understanding and potential utilization of MIAT.
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No.5 Beixiange Street, Xicheng District, Beijing 100053, China; Graduate School, Beijing University of Chinese Medicine, No.11 Beisanhuan East Road, Chaoyang District, Beijing 100029, China.
authors.forename: Jiangquan
authors.initials: J
authors.lastname: Liao
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No.5 Beixiange Street, Xicheng District, Beijing 100053, China.
authors.forename: Qingyong
authors.initials: Q
authors.lastname: He
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No.5 Beixiange Street, Xicheng District, Beijing 100053, China; Graduate School, Beijing University of Chinese Medicine, No.11 Beisanhuan East Road, Chaoyang District, Beijing 100029, China.
authors.forename: Min
authors.initials: M
authors.lastname: Li
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No.5 Beixiange Street, Xicheng District, Beijing 100053, China; Graduate School, Beijing University of Chinese Medicine, No.11 Beisanhuan East Road, Chaoyang District, Beijing 100029, China.
authors.forename: Yinfeng
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No.5 Beixiange Street, Xicheng District, Beijing 100053, China. Electronic address: lymsd@163.com.
authors.forename: Yongmei
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No.5 Beixiange Street, Xicheng District, Beijing 100053, China. Electronic address: wangjie0103@126.com.
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
mesh_terms: D002843:Chromatin / Q000235:genetics; D003930:Diabetic Retinopathy / Q000235:genetics* / Q000473:pathology; D005786:Gene Expression Regulation; D006801:Humans; D009203:Myocardial Infarction / Q000235:genetics* / Q000473:pathology; D034622:RNA Interference; D062085:RNA, Long Noncoding / Q000235:genetics*; D012563:Schizophrenia, Paranoid / Q000235:genetics* / Q000473:pathology
chemical_list: D002843:Chromatin; C517383:Miat long non-coding RNA; D062085:RNA, Long Noncoding
keywords: GOMAFU; Long noncoding RNA; MIAT