title: Atrial Fibrillation Is Associated With Increased Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement: Insights From the Placement of Aortic Transcatheter Valve (PARTNER) Trial.
abstract: BACKGROUND
  This study sought to evaluate the impact of atrial fibrillation (AF) on clinical outcomes in patients undergoing transcatheter aortic valve replacement.
  
  
  RESULTS
  Data were evaluated in 1879 patients with baseline and discharge ECGs who underwent transcatheter aortic valve replacement in the Placement of AoRTic TraNscathetER Valve (PARTNER) trial. A total of 1262 patients manifested sinus rhythm (SR) at baseline/SR at discharge, 113 SR baseline/AF discharge, and 470 AF baseline/AF discharge. Patients who converted from SR to AF by discharge had the highest rates of all-cause mortality at 30 days (P<0.0001 across all groups; 14.2% SR/AF versus 2.6% SR/SR; adjusted hazard ratio [HR]=3.41; P=0.0002) and over 2-fold difference at 1 year (P<0.0001 across all groups; 35.7% SR/AF versus 15.8% SR/SR; adjusted HR=2.14; P<0.0001). The presence of AF on baseline or discharge ECG was a predictor of 1-year mortality (adjusted HR=2.14 for SR/AF group and HR=1.88 for AF/AF groups; P<0.0001 for both groups versus SR/SR). For patients discharged in AF, those with lower ventricular response (ie, <90 bpm) experienced less 1-year all-cause mortality (HR=0.74; P=0.04).
  
  
  CONCLUSIONS
  After transcatheter aortic valve replacement, the presence of AF at discharge, and particularly, the conversion to AF by discharge and higher ventricular response are associated with increased mortality. These data underscore the deleterious impact of AF, as well as the need for targeted interventions to improve clinical outcomes, in patients undergoing transcatheter aortic valve replacement.
  
  
  BACKGROUND
  URL: http://www.clinicaltrials.gov. Unique identifier: NCT00530894.
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.). ab542@columbia.edu.
authors.forename: Angelo B
authors.initials: AB
authors.lastname: Biviano
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Tamim
authors.initials: T
authors.lastname: Nazif
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Jose
authors.initials: J
authors.lastname: Dizon
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Hasan
authors.initials: H
authors.lastname: Garan
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Jessica
authors.initials: J
authors.lastname: Fleitman
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Dua
authors.initials: D
authors.lastname: Hassan
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Samir
authors.initials: S
authors.lastname: Kapadia
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Vasilis
authors.initials: V
authors.lastname: Babaliaros
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Ke
authors.initials: K
authors.lastname: Xu
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Rupa
authors.initials: R
authors.lastname: Parvataneni
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Josep
authors.initials: J
authors.lastname: Rodes-Cabau
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Wilson Y
authors.initials: WY
authors.lastname: Szeto
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: William F
authors.initials: WF
authors.lastname: Fearon
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Danny
authors.initials: D
authors.lastname: Dvir
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Todd
authors.initials: T
authors.lastname: Dewey
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Mathew
authors.initials: M
authors.lastname: Williams
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Mack
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: John G
authors.initials: JG
authors.lastname: Webb
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: D Craig
authors.initials: DC
authors.lastname: Miller
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Craig R
authors.initials: CR
authors.lastname: Smith
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon
authors.affiliation: From the Department of Medicine (A.B.B., T.N., J.D., H.G., J.F., D.H., M.B.L., S. Kodali) and Department of Surgery (C.R.S.), Columbia University Medical Center, New York Presbyterian Hospital, NY; Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia); Division of Cardiology, Emory University, Atlanta, GA (V.B.); Cardiovascular Research Foundation, New York, NY (K.X., R.P., M.B.L.); Quebec Heart & Lung Institute, Laval University, Quebec City, QC, Canada (J.R.-C.); Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia (W.Y.S.); Department of Medicine (W.F.F.) and Department of Cardiovascular Surgery (D.C.M.), Stanford University, CA; Department of Medicine, Division of Cardiology, St. Paul's Hospital, Vancouver, BC, Canada (D.D., J.G.W.); Thoracic Surgery, Medical City Dallas, TX (T.D.); Department of Cardiothoracic Medicine and Department of Medicine, NYU Langone Medical Center, New York, NY (M.W.); Cardiothoracic Surgery, Baylor Scott & White Health, Plano, TX (M.J.M.).
authors.forename: Susheel
authors.initials: S
authors.lastname: Kodali
mesh_terms: D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000401:mortality / Q000601:surgery*; D001955:British Columbia / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D006801:Humans; D015994:Incidence; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology*; D016016:Proportional Hazards Models; D012720:Severity of Illness Index; D015996:Survival Rate / Q000639:trends; D013997:Time Factors; D065467:Transcatheter Aortic Valve Replacement / Q000401:mortality*; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
keywords: aortic valve; atrial fibrillation; atrial flutter; mortality; transcatheter aortic valve replacement