title: Complete genome sequence of Streptomyces venezuelae ATCC 15439, a promising cell factory for production of secondary metabolites.
abstract: Streptomyces venezuelae ATCC 15439, which produces 12- and 14-membered ring macrolide antibiotics, is a platform strain for heterologous expression of secondary metabolites. Its 9.05-Mb genome sequence revealed an abundance of genes involved in the biosynthesis of secondary metabolites and their precursors, which should be useful for the production of bioactive compounds.
authors.affiliation: Department of Systems Biology and Division of Life Sciences, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
authors.forename: Ju Yeon
authors.initials: JY
authors.lastname: Song
authors.affiliation: Department of Chemistry and Nanoscience, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Republic of Korea.
authors.forename: Young Ji
authors.initials: YJ
authors.lastname: Yoo
authors.affiliation: GenoTech Corporation, 26-69 Gajeongbuk-ro, Daejeon 34113, Republic of Korea.
authors.forename: Si-Kyu
authors.initials: SK
authors.lastname: Lim
authors.affiliation: GenoTech Corporation, 26-69 Gajeongbuk-ro, Daejeon 34113, Republic of Korea.
authors.forename: Sun Ho
authors.initials: SH
authors.lastname: Cha
authors.affiliation: School of Biological Sciences and Institute of Microbiology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.
authors.forename: Ji-Eun
authors.initials: JE
authors.lastname: Kim
authors.affiliation: School of Biological Sciences and Institute of Microbiology, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.
authors.forename: Jung-Hye
authors.initials: JH
authors.lastname: Roe
authors.affiliation: Department of Systems Biology and Division of Life Sciences, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea; Strategic Initiative for Microbiomes in Agriculture and Food, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea. Electronic address: jfk1@yonsei.ac.kr.
authors.forename: Jihyun F
authors.initials: JF
authors.lastname: Kim
authors.affiliation: Department of Chemistry and Nanoscience, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Republic of Korea. Electronic address: joonyoon@ewha.ac.kr.
authors.forename: Yeo Joon
authors.initials: YJ
authors.lastname: Yoon
mesh_terms: D001482:Base Composition; D059646:Genome Size; D016680:Genome, Bacterial; D064210:Secondary Metabolism; D017422:Sequence Analysis, DNA / Q000379:methods*; D013302:Streptomyces / Q000235:genetics*
keywords: Actinomycetes; Methymycin; Natural products; Pikromycin; Secondary metabolism