title: Detection of bovine leukemia virus and identification of its genotype in Mongolian cattle.
abstract: Epidemiological studies have indicated that bovine leukemia virus (BLV) infection is globally distributed. However, no information regarding the disease and genetic diversity of the virus in the cattle of Mongolia is currently available. In this study, the prevalence of BLV was assessed using PCR, and the genetic diversity was analyzed through DNA sequencing. Of the 517 samples tested, 20 positives were identified. Phylogenetic analysis showed that six, one, and four isolates were classified into genotype 4, 7, and 1, respectively. Most isolates were clustered with isolates from Eastern Europe and Russia. This study is the first to investigate the BLV genotype in Mongolia.
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.
authors.forename: Nyamsuren
authors.initials: N
authors.lastname: Ochirkhuu
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Konnai
authors.affiliation: Laboratory of Virology, Institute of Veterinary Medicine, Mongolia University of Life Science, Khan-Uul District, Zaisan, Ulaanbaatar, 17042, Mongolia.
authors.forename: Raadan
authors.initials: R
authors.lastname: Odbileg
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.
authors.forename: Asami
authors.initials: A
authors.lastname: Nishimori
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Okagawa
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Murata
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, 060-0818, Japan. okazu@vetmed.hokudai.ac.jp.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Ohashi
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000956:Antigens, Viral; D002417:Cattle; D016583:Enzootic Bovine Leukosis / Q000453:epidemiology / Q000821:virology*; D015967:Gene Expression Regulation, Viral; D005838:Genotype; D001909:Leukemia Virus, Bovine / Q000235:genetics*; D008969:Molecular Sequence Data; D008986:Mongolia / Q000453:epidemiology; D010802:Phylogeny; D016415:Sequence Alignment; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D000956:Antigens, Viral; D014764:Viral Proteins