title: Clinicoanatomical correlation in stroke related aphasia.
abstract: BACKGROUND
  With advances in neuroimaging, traditional views regarding the clinicoanatomic correlation in stroke patients with aphasia are being challenged and it has been observed that lesions at a given cortical or subcortical site may manifest with different aphasia profiles.
  
  
  OBJECTIVE
  To study as to whether there is a strict clinicoanatomical correlation between the type of aphasia and lesion site in patients with first ever stroke.
  
  
  METHODS
  Observational study, based in a tertiary care center.
  
  
  METHODS
  Stroke patient's ≥18 years of age were screened and those with first ever stroke and aphasia were subjected to a detailed stroke workup and language assessment using the Hindi version of Western Aphasia Battery (WAB). Statistical analysis was done with χ(2) test with Yates correction and Kruskal-Wallis test. The level of significance was set at P < 0.05.
  
  
  RESULTS
  Overall aphasia was detected in 27.9% of the 260 screened cases with stroke. Amongst 60 cases with first ever stroke and aphasia, the aphasia type was: Global (33.33%), Broca's (28.3%), transcortical motor (13.33%), transcortical sensory (10%), Wernicke's (8.33%), anomic (5%), and conduction (1.67%) aphasia. A definite correlation between the lesion site and the type of aphasia as per the traditional classification was observed in 35% cases only.
  
  
  CONCLUSIONS
  No absolute correlation exists between the lesion site and the type of clinical aphasia syndrome in majority of the patients with cortical and subcortical stroke.
authors.affiliation: Department of Neurology, Govind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India.
authors.forename: Vikram
authors.initials: V
authors.lastname: Bohra
authors.affiliation: Department of Neurology, Govind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India.
authors.forename: Geeta Anjum
authors.initials: GA
authors.lastname: Khwaja
authors.affiliation: Department of Audiology and Speech Therapy, Govind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India.
authors.forename: Sneh
authors.initials: S
authors.lastname: Jain
authors.affiliation: Department of Neurology, Govind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Duggal
authors.affiliation: Department of Neurology, Govind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India.
authors.forename: Vijay Vishwanath
authors.initials: VV
authors.lastname: Ghuge
authors.affiliation: Department of Neurology, Govind Ballabh Pant Hospital and Maulana Azad Medical College, New Delhi, India.
authors.forename: Abhilekh
authors.initials: A
authors.lastname: Srivastava
keywords: Aphasia; clinico-anatomic correlation; clinico-topographic correlation; stroke