title: Cognitive assessment strategies in Huntington's disease research.
abstract: The number of studies examining cognition in Huntington's disease (HD) has increased dramatically in recent decades, and cognitive research methods in HD have become much more sophisticated. In this review, we provide a summary of the advances in cognitive research in HD to date, and outline the key considerations for researchers planning to include cognitive assessment in their studies of HD. In particular, we discuss consideration of structure-function relationships, selection of tests appropriate to the population, choice of materials and issues of intellectual property, consideration of variables which can confound studies of cognition in HD, practice effects, and specific issues for multi-site research. Finally, we discuss future directions for cognitive assessment in HD research.
authors.affiliation: Monash Institute of Cognitive and Clinical Neuroscience, School of Psychological Sciences, Monash University 18 Innovation Walk, Clayton 3800, VIC, Australia. Electronic address: Julie.Stout@Monash.edu.
authors.forename: Julie C
authors.initials: JC
authors.lastname: Stout
authors.affiliation: Monash Institute of Cognitive and Clinical Neuroscience, School of Psychological Sciences, Monash University 18 Innovation Walk, Clayton 3800, VIC, Australia. Electronic address: Yifat.Glikmann-Johnston@Monash.edu.
authors.forename: Yifat
authors.initials: Y
authors.lastname: Glikmann-Johnston
authors.affiliation: Monash Institute of Cognitive and Clinical Neuroscience, School of Psychological Sciences, Monash University 18 Innovation Walk, Clayton 3800, VIC, Australia. Electronic address: Sophie.Andrews@Monash.edu.
authors.forename: Sophie C
authors.initials: SC
authors.lastname: Andrews
mesh_terms: D003071:Cognition; D006801:Humans; D006816:Huntington Disease / Q000523:psychology*; D015337:Multicenter Studies as Topic / Q000379:methods; D011581:Psychological Tests
keywords: Cognition; Cognitive assessment; Huntington's disease; Practice effects; Research design; Test selection