title: Manufacturing of microcirculation phantoms using rapid prototyping technologies.
abstract: In this paper, we describe a method for the manufacturing of a microcirculation phantom that may be used to investigate hemodynamics using optics based methods. We made an Acrylonitrile Butadiene Styrene (ABS) negative mold, manufactured in a Fused Deposition Modelling (FDM) printer, embedded it in Polydimethysilioxane (PDMS) and dissolved it from within using acetone. We successfully made an enlarged three-dimensional (3D) network of microcirculation, and tested it using red blood cell (RBC) analogues. This phantom may be used for testing medical imaging technology.
authors.forename: Anthony
authors.initials: A
authors.lastname: Buchoux
authors.forename: Prashant
authors.initials: P
authors.lastname: Valluri
authors.forename: Stewart
authors.initials: S
authors.lastname: Smith
authors.forename: Adam A
authors.initials: AA
authors.lastname: Stokes
authors.forename: Peter R
authors.initials: PR
authors.lastname: Hoskins
authors.forename: Vassilis
authors.initials: V
authors.lastname: Sboros
mesh_terms: D002070:Butadienes / Q000737:chemistry; D003952:Diagnostic Imaging / Q000295:instrumentation*; D008833:Microcirculation / Q000502:physiology*; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D020058:Styrene / Q000737:chemistry
chemical_list: D002070:Butadienes; D020058:Styrene; C031763:1,3-butadiene