title: A Case of Tumor Lysis Syndrome in a Patient with Pancreatic Adenocarcinoma Treated with Low-Dose Gemcitabine.
abstract: BACKGROUND
  Tumor lysis syndrome (TLS) is a common adverse consequence of treatment of high-grade hematologic malignancies that has been known to occur rarely in some solid tumors, including small cell lung cancer, breast cancer, colorectal cancer, neuroblastoma, ovarian cancer, and hepatocellular carcinoma.
  
  
  METHODS
  We present a case of TLS in a patient with pancreatic adenocarcinoma treated with one small dose of gemcitabine. To our knowledge, this phenomenon has only been described once prior in the medical literature and never with a reduced dose of chemotherapy.
  
  
  CONCLUSIONS
  This case reveals the need for heightened awareness of TLS in patients with solid tumors, especially in patients with pancreatic adenocarcinoma.
authors.affiliation: Department of Internal Medicine, Advocate Christ Medical Center, Oak Lawn, IL.
authors.forename: Taylor
authors.initials: T
authors.lastname: Brinton
authors.affiliation: Department of Internal Medicine, Advocate Christ Medical Center, Oak Lawn, IL.
authors.forename: Tariq
authors.initials: T
authors.lastname: Yousuf
authors.affiliation: Department of Hematology/Oncology, Advocate Christ Medical Center, Oak Lawn, IL.
authors.forename: Gary
authors.initials: G
authors.lastname: Steinecker
authors.affiliation: Department of Nephrology, Advocate Christ Medical Center, Oak Lawn, IL.
authors.forename: James
authors.initials: J
authors.lastname: Rydel
keywords: Adenocarcinoma; gemcitabine; tumor lysis syndrome