title: Mind-Body Interactions in Anxiety and Somatic Symptoms.
abstract: Anxiety and somatic symptoms have a high prevalence in the general population. A mechanistic understanding of how different factors contribute to the development and maintenance of these symptoms, which are highly associated with anxiety disorders, is crucial to optimize treatments. In this article, we review recent literature on this topic and present a redefined model of mind-body interaction in anxiety and somatic symptoms, with an emphasis on both bottom-up and top-down processes. Consideration is given to the role played in this interaction by predisposing physiological and psychological traits (e.g., interoception, anxiety sensitivity, and trait anxiety) and to the levels at which mindfulness approaches may exert a therapeutic benefit. The proposed model of mind-body interaction in anxiety and somatic symptoms is appraised in the context of joint hypermobility syndrome, a constitutional variant associated with autonomic abnormalities and vulnerability to anxiety disorders.
authors.affiliation: From the Department of Psychiatry, Brighton and Sussex Medical School (Drs. Mallorquí-Bagué, Garfinkel, and Critchley), and Sackler Centre for Consciousness Science (Drs. Garfinkel and Critchley), University of Sussex; Department of Psychiatry and Forensic Medicine, School of Medicine (Drs. Mallorquí-Bagué, Bulbena, and Pailhez), and Anxiety Unit, Institute of Neuropsychiatry and Addictions, Hospital del Mar (Drs. Bulbena and Pailhez), Universitat Autònoma de Barcelona; Psychiatry, Psychology and Psychosomatics Department, Institut Universitari Quirón Dexeus, Barcelona (Dr. Mallorquí-Bagué); Hospital del Mar Medical Research Institute, Barcelona (Drs. Bulbena and Pailhez); Mood and Anxiety Research Sussex, Sussex Partnership NHS Foundation Trust, UK (Drs. Garfinkel and Critchley).
authors.forename: Núria
authors.initials: N
authors.lastname: Mallorquí-Bagué
authors.forename: Antonio
authors.initials: A
authors.lastname: Bulbena
authors.forename: Guillem
authors.initials: G
authors.lastname: Pailhez
authors.forename: Sarah N
authors.initials: SN
authors.lastname: Garfinkel
authors.forename: Hugo D
authors.initials: HD
authors.lastname: Critchley
mesh_terms: D001007:Anxiety / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D065812:Interoception / Q000502:physiology; D019222:Mind-Body Relations, Metaphysical / Q000502:physiology; D008954:Models, Biological; D020886:Somatosensory Disorders / Q000209:etiology* / Q000503:physiopathology