title: Catalytic cycloaddition of 2-hydroxy ketones with 1,1-dicyanoalkenes.
abstract: A tin-catalyzed reaction of α-hydroxy ketones with 1,1-dicyanoalkenes produced 2-amino-4,5-dihydrofuran-3-nitriles. In the catalytic reaction, tin enolates were generated from α-hydroxy ketones as active catalytic species. The highly basic ability of the Sn-O bonds played an important role in the reactions. This tin-catalyzed reaction was highly atom-economical and required no other metal reagents.
authors.affiliation: Research Center for Environmental Preservation, Osaka University, 2-4 Yamadaoka, Suita, Osaka 565-0871, Japan. shibata@epc.osaka-u.ac.jp.
authors.forename: Shinji
authors.initials: S
authors.lastname: Tsunoi
authors.affiliation: Research Center for Environmental Preservation, Osaka University, 2-4 Yamadaoka, Suita, Osaka 565-0871, Japan. shibata@epc.osaka-u.ac.jp.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Seo
authors.affiliation: Research Center for Environmental Preservation, Osaka University, 2-4 Yamadaoka, Suita, Osaka 565-0871, Japan. shibata@epc.osaka-u.ac.jp.
authors.forename: Yugo
authors.initials: Y
authors.lastname: Takano
authors.affiliation: Research Center for Environmental Preservation, Osaka University, 2-4 Yamadaoka, Suita, Osaka 565-0871, Japan. shibata@epc.osaka-u.ac.jp.
authors.forename: Itaru
authors.initials: I
authors.lastname: Suzuki
authors.affiliation: Research Center for Environmental Preservation, Osaka University, 2-4 Yamadaoka, Suita, Osaka 565-0871, Japan. shibata@epc.osaka-u.ac.jp.
authors.forename: Ikuya
authors.initials: I
authors.lastname: Shibata