title: Ten-year Survival and Its Associated Factors in the Patients Undergoing Pacemaker Implantation in Hospitals Affiliated to Shiraz University of Medical Sciences During 2002 - 2012.
abstract: BACKGROUND
  Heart failure is a prevalent disease affecting about 4.9 million people in the U.S. and more than 22 million individuals worldwide. Using electric pacemaker is the most common treatment for the patients with heart conduction problems. The present study aimed to determine the factors affecting survival in the patients undergoing pacemaker implantation in the hospitals affiliated to Shiraz University of Medical Sciences.
  
  
  OBJECTIVE
  The aim of the present study was to identify the factors affecting the survival of the patients suffering from arrhythmia.
  
  
  METHODS
  This retrospective survival analysis was conducted on all 1207 patients with heart failure who had undergone permanent pacemaker implantation in the hospitals affiliated to Shiraz University of Medical Sciences from 2002 to 2012. The data were analyzed using non-parametric methods such as Kaplan-Meier method, life table, and Cox regression model. The risk factors of mortality were determined using multivariate Cox proportional hazards method.
  
  
  RESULTS
  Survival data were available for 1030 (80%) patients (median age = 71 years [5th to 95th percentile range: 26 - 86 years]) and follow-up was completed for 84.28% of them. According to the results, 56% of the patients had received dual-chamber systems, while 44% had been implanted by single-chamber ventricular systems. Moreover, sick sinus syndrome and pacemaker mode were independent predictors of increased mortality.
  
  
  CONCLUSIONS
  In this study, sick sinus syndrome and pacemaker mode followed by syncope were independently associated with increased mortality.
authors.affiliation: Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Abdolreza
authors.initials: A
authors.lastname: Rajaeefard
authors.affiliation: Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Ghorbani
authors.affiliation: Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Babaee Baigi
authors.affiliation: Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Hamidreza
authors.initials: H
authors.lastname: Tabatabae
keywords: Pacemaker, Artificial; Risk Factors; Survival Analysis