title: Asymmetric behaviours of brain oscillations in the human hippocampus during spatial navigation tasks.
abstract: Hippocampal-dependent memory functions may be lateralized to the right hippocampus during spatial navigation. However, direct electrophysiological evidence supporting these findings in the bilateral hippocampi during spatial navigation has not been well documented in humans. We studied changes in brain oscillations between the dominant and the nondominant hippocampi during encoding periods of environmental novelty using spatial navigation tasks. Results showed that brain oscillations during the encoding period of spatial navigation increased significantly in the nondominant hippocampus compared with the dominant hippocampus. These findings provide direct electrophysiological evidence that the nondominant hippocampus plays a predominant role in spatial navigation.
authors.affiliation: aDepartment of Neurology, Asan Medical Center, College of Medicine University of Ulsan, Seoul, Korea bDepartment of Biomedical Engineering, Hanyang University, Seoul, Korea cDepartment of Neurology, Ulsan University Hospital, Ulsan, Korea.
authors.forename: Joong Koo
authors.initials: JK
authors.lastname: Kang
authors.forename: Eun Mi
authors.initials: EM
authors.lastname: Lee
authors.forename: Dajeong
authors.initials: D
authors.lastname: Kim
authors.forename: Seong
authors.initials: S
authors.lastname: Hye Lee
authors.forename: Taekyung
authors.initials: T
authors.lastname: Kim
authors.forename: Young Min
authors.initials: YM
authors.lastname: Park
authors.forename: Jinsick
authors.initials: J
authors.lastname: Park
authors.forename: Sun I
authors.initials: SI
authors.lastname: Kim
authors.forename: In Young
authors.initials: IY
authors.lastname: Kim
authors.forename: Dong Pyo
authors.initials: DP
authors.lastname: Jang
mesh_terms: D000328:Adult; D058256:Brain Waves / Q000502:physiology*; D004567:Electrodes, Implanted; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D008297:Male; D065854:Spatial Navigation / Q000502:physiology*