title: First report of lukM-positive livestock-associated methicillin-resistant Staphylococcus aureus CC30 from fattening pigs in Northern Ireland.
abstract: The increasing number of reports of livestock-associated meticillin-resistant Staphylococcus aureus (LA-MRSA) world-wide attests to the public health concern surrounding this pathogen in animal husbandry and in-contact humans. In Europe, LA-MRSA CC398 is predominant and generally regarded as being of low virulence for animals. Herein we report the recovery of a lineage of LA-MRSA, belonging to CC30, from three pigs in Northern Ireland and which encodes a marker of virulence (lukM and lukF-P83) restricted to animal-associated clones of S. aureus.
authors.affiliation: Agri-food and Biosciences Institute (AFBI), Stoney Road, BT4 3SD Belfast, UK. Electronic address: angela.lahuerta-marin@afbini.gov.uk.
authors.forename: Angela
authors.initials: A
authors.lastname: Lahuerta-Marin
authors.affiliation: Agri-food and Biosciences Institute (AFBI), Stoney Road, BT4 3SD Belfast, UK.
authors.forename: Maria
authors.initials: M
authors.lastname: Guelbenzu-Gonzalo
authors.affiliation: Public Health England (PHE), 61 Colindale Avenue, NW9 5EQ London, UK.
authors.forename: Bruno
authors.initials: B
authors.lastname: Pichon
authors.affiliation: Agri-food and Biosciences Institute (AFBI), Stoney Road, BT4 3SD Belfast, UK.
authors.forename: Adrian
authors.initials: A
authors.lastname: Allen
authors.affiliation: Public Health England (PHE), 61 Colindale Avenue, NW9 5EQ London, UK.
authors.forename: Michel
authors.initials: M
authors.lastname: Doumith
authors.affiliation: Agri-food and Biosciences Institute (AFBI), Stoney Road, BT4 3SD Belfast, UK.
authors.forename: John F
authors.initials: JF
authors.lastname: Lavery
authors.affiliation: Agri-food and Biosciences Institute (AFBI), Stoney Road, BT4 3SD Belfast, UK.
authors.forename: Conrad
authors.initials: C
authors.lastname: Watson
authors.affiliation: Animal Health and Plant Agency (APHA), Kendal Road, Shrewsbury, Shropshire SY1 4HD, UK.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Teale
authors.affiliation: Public Health England (PHE), 61 Colindale Avenue, NW9 5EQ London, UK.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Kearns
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics / Q000378:metabolism*; D009660:Northern Ireland / Q000453:epidemiology; D010802:Phylogeny; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000382:microbiology*
chemical_list: D001426:Bacterial Proteins; C091659:LukM protein, Staphylococcus aureus
keywords: Clonal Complex 30; LA-MRSA; Methicillin-resistant Staphylococcus aureus; Pigs; lukM