title: Gastric Bypass in Older Patients: Complications, Weight Loss, and Resolution of Comorbidities at 2 Years in a Matched Controlled Study.
abstract: Roux-en-Y gastric bypass (RYGB) has recently been authorized for use in older patients. The objective of this single-center study was to evaluate 2-year weight loss in patients ≥60 years compared with younger matched patients undergoing RYGB. Secondary aims were to record complications and the resolution of comorbidities in a 2-year follow-up.
  
  
  
  Of 722 patients with at least 2 years follow-up data, 48 elderly patients were matched with 92 young (<40 years) and 96 middle-aged (40-59 year) patients, according to sex, baseline body mass index, and date of surgery. Weight loss, remission of comorbidities, death, and early (30-day) and 2-year complication rates were compared.
  
  
  
  There were three deaths in the elderly group and none in the other groups. The early complication rate was not significantly different in the elderly group (17.8 %) compared with the young (11.5 %, p = 0.637) and middle-aged (13.7 %, p = 1.000) groups. The 2-year complication rates were not significantly different in the elderly group (9.3 %) compared with the young (23.5 %, p = 0.107) and middle-aged (13.2 %, p = 1.000) groups. The 2-year weight loss was lower in the elderly group (31.8 ± 7.2 %; p < 0.001) than in the young group (38.3 ± 6.9 %) but was not significantly different from that in the middle-aged group (34.4 ± 8.0 %; p = 0.145). Remission rates for diabetes and obstructive sleep apnea were lower in the elderly than in the two younger groups.
  
  
  
  After bariatric surgery, major weight loss was observed in patients older than 60, but remission of metabolic comorbidities was less marked than in younger subjects.
authors.affiliation: UMR1048 INSERM, Obesity Research Laboratory, Institute of Metabolic and Cardiovascular Diseases (I2MC), University of Toulouse III, Toulouse, France.|Department of Nutrition, Toulouse University Hospital, Toulouse, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Montastier
authors.affiliation: Clinique de l'Anjou, Bariatric Surgery Department, Angers, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Becouarn
authors.affiliation: Department of Epidemiology, Health Economics and Public Health, Toulouse University Hospital, Toulouse, France.|UMR1027 INSERM-University of Toulouse III, Toulouse, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Bérard
authors.affiliation: Gérontopôle, Toulouse University Hospital; UMR1027, INSERM-University of Toulouse III, Toulouse, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Guyonnet
authors.affiliation: Clinique de l'Anjou, Bariatric Surgery Department, Angers, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Topart
authors.affiliation: Department of Nutrition, Toulouse University Hospital, Toulouse, France. patrick.ritz@wanadoo.fr.|UMR1027 INSERM-University of Toulouse III, Toulouse, France. patrick.ritz@wanadoo.fr.
authors.forename: Patrick
authors.initials: P
authors.lastname: Ritz
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D015390:Gastric Bypass; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D020181:Sleep Apnea, Obstructive / Q000150:complications*; D016896:Treatment Outcome; D015431:Weight Loss; D055815:Young Adult
keywords: Diabetes; Hypertension; Obesity surgery; Obstructive sleep apnea; Remission