title: Epithelial mesenchymal transition in lung cancer cells: A quantitative analysis.
abstract: Cellular auto-fluorescence along with morphological and cytoskeletal features were assessed in lung cancer cells undergoing induced epithelial mesenchymal transition (EMT). During EMT progression, significant increase was observed in cellular aspect ratio (AR), filamentous (F)-actin and green auto-fluorescence intensities while blue intensity decreased. These features were provided to a kernel classification framework. The classification accuracy were impressive, thus these features along with the classification technique can be considered as suitable tools for automated grading of lung cancer cells undergoing EMT progression.
authors.forename: Atasi
authors.initials: A
authors.lastname: Sarkar
authors.forename: A
authors.initials: A
authors.lastname: Barui
authors.forename: S
authors.initials: S
authors.lastname: Sengupta
authors.forename: J
authors.initials: J
authors.lastname: Chatterjee
authors.forename: S
authors.initials: S
authors.lastname: Ghorai
authors.forename: Anirban
authors.initials: A
authors.lastname: Mukherjee
mesh_terms: D045744:Cell Line, Tumor; D058750:Epithelial-Mesenchymal Transition / Q000502:physiology*; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology*