title: High temporal resolution functional MRI with partial separability model.
abstract: Even though the hemodynamic response is a slow phenomenon, high temporal resolution in functional fMRI can enable better differentiation between the signal of interest and physiological noise or increase the statistical power of functional studies. To increase the temporal resolution, several methods have been developed to decrease the repetition time, TR, such as simultaneous multi-slice imaging and MR encephalography approaches. In this work, a method using a fast acquisition and a partial separability model is presented to achieve a multi-slice fMRI protocol at a temporal resolution of 75 ms. The method is demonstrated on a visual block task.
authors.forename: Giang-Chau
authors.initials: GC
authors.lastname: Ngo
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Holtrop
authors.forename: Maojing
authors.initials: M
authors.lastname: Fu
authors.forename: Fan
authors.initials: F
authors.lastname: Lam
authors.forename: Bradley P
authors.initials: BP
authors.lastname: Sutton
mesh_terms: D000465:Algorithms; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008962:Models, Theoretical; D012815:Signal Processing, Computer-Assisted; D017550:Spectroscopy, Fourier Transform Infrared; D013647:Task Performance and Analysis; D013997:Time Factors; D014793:Visual Cortex / Q000502:physiology