title: CFD analysis of unsteady flow through conjoining Aorta and aortic isthmus.
abstract: The initial stages of fetal development require that blood oxygenation occur through the placenta rather than the non functioning lungs. As a result the fetal circulatory system develops a temporary shunt between the aorta and pulmonary artery, known as the ductus arteriosis (DA). This study utilizes CFD techniques to analyze the flow behavior in the aortic isthmus neighboring the DA. The geometry used to represent these structures is equivalent to that of a 25 week old fetus. The effect of aortic and pulmonary pressure pulse wave delay is examined for producing flow disturbances in the fetal circulatory system. This is accomplished by analyzing both axial and tangential flow fields downstream of the DA. The study demonstrates that there exist different swirl profiles that are related to the timing of pulse contributions from both the left and right ventricles.
authors.forename: Amy-Lee
authors.initials: AL
authors.lastname: Gunter
authors.forename: Zahra
authors.initials: Z
authors.lastname: Keshavarz-Motamed
authors.forename: Rocco
authors.initials: R
authors.lastname: Portaro
authors.forename: Lyes
authors.initials: L
authors.lastname: Kadem
authors.forename: Hoi Dick
authors.initials: HD
authors.lastname: Ng
mesh_terms: D001011:Aorta; D001783:Blood Flow Velocity; D005260:Female; D005333:Fetus; D006352:Heart Ventricles; D006801:Humans; D011247:Pregnancy; D011651:Pulmonary Artery