title: Magnetic solid phase extraction and static headspace gas chromatography-mass spectrometry method for the analysis of polycyclic aromatic hydrocarbons.
abstract: A magnetic solid phase extraction (MSPE) protocol combining a static headspace gas chromatography coupled to mass spectrometry (HS-GC-MS) method has been developed for extraction, and determination of 16 polycyclic aromatic hydrocarbons (PAHs) in drinking water samples. Magnetic nanoparticles (MNPs) were coated with 3-aminopropyltriethoxysilane and modified by cholesterol chloroformate. Transmission electron microscope, vibrating sample magnetometer, Fourier transform infrared spectrometry and X-ray photoelectron spectroscopy were used to characterize the cholesterol-functionalized sorbents, and the main parameters affecting the extraction as well as HS sampling, such as sorbent amount, extraction time, oven temperature and equilibration time have been investigated and established. Combination with HS sampling, the MSPE procedure was simple, fast and environmentally friendly, without need of any organic solvent. Method validation proved the feasibility of the developed sorbents for the quantitation of the investigated analytes at trace levels obtaining the limit of detection (S/N=3) ranging from 0.20 to 7.8 ng/L. Good values for intra and inter-day precision were obtained (RSDs ≤ 9.9%). The proposed method was successfully applied to drinking water samples.
authors.affiliation: State Key Laboratory of Chemo/Biosensing & Chemometrics, College of Chemistry & Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Cai
authors.affiliation: Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Yan
authors.affiliation: State Key Laboratory of Chemo/Biosensing & Chemometrics, College of Chemistry & Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Lijia
authors.initials: L
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Chemo/Biosensing & Chemometrics, College of Chemistry & Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Manh
authors.initials: M
authors.lastname: NguyenVan
authors.affiliation: State Key Laboratory of Chemo/Biosensing & Chemometrics, College of Chemistry & Chemical Engineering, Hunan University, Changsha 410082, China. Electronic address: qycai0001@hnu.edu.cn.
authors.forename: Qingyun
authors.initials: Q
authors.lastname: Cai
mesh_terms: D002623:Chemistry Techniques, Analytical / Q000379:methods*; D060766:Drinking Water / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D057230:Limit of Detection; D008280:Magnetics; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*; D052616:Solid Phase Extraction; D012997:Solvents / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000032:analysis
chemical_list: D060766:Drinking Water; D011084:Polycyclic Aromatic Hydrocarbons; D012997:Solvents; D014874:Water Pollutants, Chemical
keywords: Cholesterol-functionalized MNPs; Environmentally friendly; Headspace sampling; Polycyclic aromatic hydrocarbons