title: Active Surveillance for Small Renal Masses: A Review of the Aims and Preliminary Results of the DISSRM Registry.
abstract: Active surveillance is an increasingly accepted treatment modality for select patients with small renal masses. The DISSRM (delayed intervention and surveillance for small renal masses) registry is a multi-institutional, prospectively collected data repository which includes patients who select active surveillance for their small renal masses, as well as others who select immediate intervention. Preliminary results from the registry suggest oncological equivalence of active surveillance and surgical modalities in the intermediate term. Additionally, the registry provides the first published data regarding trends in renal function among patients undergoing active surveillance. On average, these patients experience a decline in renal function, and their renal functional outcomes are superior to those of patients undergoing radical nephrectomy, but do not significantly differ from those of patients undergoing partial nephrectomy.
authors.affiliation: Herbert Irving Cancer Center, Columbia University College of Physicians and Surgeons, Department of Urology, New York, NY, USA. mdanzig@med.umich.edu.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Danzig
authors.affiliation: Division of Urology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
authors.forename: Peter
authors.initials: P
authors.lastname: Chang
authors.affiliation: Division of Urology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Wagner
authors.affiliation: James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Mohamad E
authors.initials: ME
authors.lastname: Allaf
authors.affiliation: Herbert Irving Cancer Center, Columbia University College of Physicians and Surgeons, Department of Urology, New York, NY, USA.
authors.forename: James M
authors.initials: JM
authors.lastname: McKiernan
authors.affiliation: James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Phillip M
authors.initials: PM
authors.lastname: Pierorazio
mesh_terms: D001706:Biopsy; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000473:pathology* / Q000503:physiopathology; D007680:Kidney Neoplasms / Q000601:surgery; D009392:Nephrectomy / Q000379:methods; D012042:Registries
keywords: Glomerular filtration rate; Nephrectomy; Renal neoplasms