title: [Low mean cell hemoglobin is a reliable marker for iron deficiency screening].
abstract: BACKGROUND
  Screening for iron deficiency, which affects a significant proportion of the population, is a burning issue in the health care system.
  
  
  OBJECTIVE
  The aim of the authors was to examine whether low mean cell hemoglobin concentration measured by automated hematology analyzers is a suitable screening parameter for iron deficiency.
  
  
  METHODS
  The data for this study included a total of 247,705 complete blood counts and 10,840 tests with different parameters of iron metabolism. Patients were evaluated at Somogy County Kaposi Mór Teaching Hospital during a period of 30 months between January 1, 2013 and June 30, 2015. Low cell hemoglobin values were analyzed with iron metabolism parameters measured simultaneously.
  
  
  RESULTS
  A total of 830 patients whose iron metabolism parameters were measured simultaneously had low mean cell hemoglobin (<28pg). Of the 830 patients, 679 (82%) had both low mean cell hemoglobin and iron deficiency, while in 126 hemodialysed patients (15%), 8 patients with myelofibrosis, and 5 patients with rheumatic arthritis had low mean cell hemoglobin without iron deficiency. In the remaining 6 patients the cause of low mean cell hemoglobin or iron deficiency was not identified.
  
  
  CONCLUSIONS
  Based on these findings the authors conclude that mean cell hemoglobin may be a reliable screening marker for iron deficiency.
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Sára Vászana
authors.initials: SV
authors.lastname: Kellner
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Ádám
authors.initials: Á
authors.lastname: Kellner
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Attila
authors.initials: A
authors.lastname: Haragh
authors.affiliation: Szent Borbála Kórház Tatabánya.
authors.forename: Péter
authors.initials: P
authors.lastname: Dombi
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Éva
authors.initials: É
authors.lastname: Karádi
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Péter
authors.initials: P
authors.lastname: Rajnics
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Balázs
authors.initials: B
authors.lastname: Kollár
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Hussain
authors.initials: H
authors.lastname: Alizadeh
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Meenakshi
authors.initials: M
authors.lastname: Ghosh
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Andrea
authors.initials: A
authors.lastname: Liposits
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Mariann
authors.initials: M
authors.lastname: Moizs
authors.affiliation: Somogy Megyei Kaposi Mór Oktató Kórház Kaposvár.
authors.forename: Miklós
authors.initials: M
authors.lastname: Egyed
mesh_terms: D000328:Adult; D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000175:diagnosis* / Q000453:epidemiology; D015415:Biomarkers / Q000097:blood; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D011237:Predictive Value of Tests; D055728:Primary Myelofibrosis / Q000150:complications; D006435:Renal Dialysis / Q000009:adverse effects; D015203:Reproducibility of Results
chemical_list: D015415:Biomarkers
keywords: anaemia; anemia; iron deficiency; mean cell hemoglobin; vashiány; átlagos vörösvértest-hemoglobin