title: Successful golimumab therapy in four patients with refractory Takayasu's arteritis.
abstract: Recent studies suggested that anti-TNF-α biological therapies are effective in treating Takayasu's arteritis (TA) refractory to conventional immunosuppressive therapy. However, the efficacy of golimumab (GLM) for TA therapy is unknown. We report four women with TA who were successfully treated with GLM. GLM was prescribed as induction therapy for three patients and as maintenance therapy for one patient. GLM showed therapeutic value and might be useful, together with other anti-TNF-α agents, in treating TA.
authors.affiliation: a The Department of Rheumatology and.
authors.forename: Rie
authors.initials: R
authors.lastname: Suematsu
authors.affiliation: a The Department of Rheumatology and.
authors.forename: Satoko
authors.initials: S
authors.lastname: Tashiro
authors.affiliation: a The Department of Rheumatology and.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Ono
authors.affiliation: a The Department of Rheumatology and.
authors.forename: Syuichi
authors.initials: S
authors.lastname: Koarada
authors.affiliation: b The Department of Adult & Gerontological Nursing , Saga University School of Medicine , Saga , Japan.
authors.forename: Akihide
authors.initials: A
authors.lastname: Ohta
authors.affiliation: a The Department of Rheumatology and.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Tada
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D013625:Takayasu Arteritis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents; C529000:golimumab
keywords: Biologics; Golimumab; Takayasu’s arteritis