title: DCD lung donation: donor criteria, procedural criteria, pulmonary graft function validation, and preservation.
abstract: In an era where there is a shortage of lungs for transplantation is increased utilization of lungs from donation after circulatory death (DCD) donors. We review the reports of 11 controlled and 1 uncontrolled DCD programs focusing on donor criteria, procedural criteria, graft assessment, and preservation techniques including the use of ex vivo lung perfusion. We have formulated conclusions and recommendations for each of these areas, which were presented at the 6th International Conference on Organ Donation. A table of recommendations, the grade of recommendations, and references are provided.
authors.affiliation: Department of Cardiothoracic Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
authors.forename: Michiel E
authors.initials: ME
authors.lastname: Erasmus
authors.affiliation: Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Dirk
authors.initials: D
authors.lastname: van Raemdonck
authors.affiliation: Nuffield Department of Surgical Sciences, Oxford Transplant Centre, University of Oxford, Oxford, UK.
authors.forename: Mohammed Zeeshan
authors.initials: MZ
authors.lastname: Akhtar
authors.affiliation: Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Arne
authors.initials: A
authors.lastname: Neyrinck
authors.affiliation: Thoracic Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
authors.forename: David Gomez
authors.initials: DG
authors.lastname: de Antonio
authors.affiliation: Thoracic Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
authors.forename: Andreas
authors.initials: A
authors.lastname: Varela
authors.affiliation: Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: John
authors.initials: J
authors.lastname: Dark
mesh_terms: D000328:Adult; D001926:Brain Death; D003226:Congresses as Topic; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007391:International Cooperation; D008171:Lung Diseases / Q000601:surgery*; D016040:Lung Transplantation / Q000379:methods / Q000592:standards*; D008875:Middle Aged; D009926:Organ Preservation / Q000379:methods*; D010477:Perfusion; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000379:methods / Q000592:standards*; D019737:Transplants; D052096:Warm Ischemia
chemical_list: D006493:Heparin
keywords: donation after cardiac death; donation after circulatory death; guidelines; lung; nonheart beating donation; review