title: Electrochemistry provides a simple way to monitor Pseudomonas aeruginosa metabolites.
abstract: Pseudomonas aeruginosa is one of the most common bacteria responsible for nosocomial infections. To imagine new therapies, understanding virulence mechanisms and the associated communication system of the bacterium (its quorum sensing) is a target of the first importance. Electrochemistry is a promising tool for real-time in situ monitoring of electroactive species issued from P. aeruginosa communication system. This contribution deals with the electrochemical characterization of the main bacteria electroactive metabolites: Pseudomonas Quinolone Signal, pyocyanin and 2'-aminoacetophenone. These metabolites were electrochemically characterized and further detected in supernatant of P. aeruginosa PA01 strain grown in LB medium.
authors.forename: Julie
authors.initials: J
authors.lastname: Oziat
authors.forename: Sylvie
authors.initials: S
authors.lastname: Elsen
authors.forename: Roisin M
authors.initials: RM
authors.lastname: Owens
authors.forename: George G
authors.initials: GG
authors.lastname: Malliaras
authors.forename: Pascal
authors.initials: P
authors.lastname: Mailley
mesh_terms: D001431:Bacteriological Techniques / Q000379:methods*; D055664:Electrochemical Techniques / Q000379:methods*; D011550:Pseudomonas aeruginosa / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000472:pathogenicity; D015363:Quinolones / Q000032:analysis / Q000378:metabolism; D053038:Quorum Sensing
chemical_list: C407944:2-heptyl-3-hydroxy-4-quinolone; D015363:Quinolones