title: Sequential Mukaiyama-Michael reaction induced by carbon acids.
abstract: In the presence of a strong carbon acid, the sequential Mukaiyama-Michael reaction using two different Michael acceptors proceeded and the reaction of ketene silyl acetal derived from EtOAc with α-pyrones as primal acceptors yielded the corresponding cyclic ketene silyl acetals, which were reactive enough to undergo the following reaction with second acceptors.
authors.affiliation: School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan. yanai@toyaku.ac.jp tmatsumo@toyaku.ac.jp.
authors.forename: Hikaru
authors.initials: H
authors.lastname: Yanai
authors.affiliation: School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan. yanai@toyaku.ac.jp tmatsumo@toyaku.ac.jp.
authors.forename: Osamu
authors.initials: O
authors.lastname: Kobayashi
authors.affiliation: Faculty of Engineering, Hokkaido University, Sapporo, Hokkaido 060-8628, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Takada
authors.affiliation: Faculty of Engineering, Hokkaido University, Sapporo, Hokkaido 060-8628, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Isono
authors.affiliation: Faculty of Engineering, Hokkaido University, Sapporo, Hokkaido 060-8628, Japan.
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Satoh
authors.affiliation: School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan. yanai@toyaku.ac.jp tmatsumo@toyaku.ac.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsumoto