title: Delayed effect of prenatal exposure to hypoxia on the susceptibility of rats to electric seizures.
abstract: We studied the delayed effects of prenatal exposure to hypoxia on the susceptibility of rats to seizures. The later was estimated using graded electroshock. The experiments were performed in two groups of 1.5-year-old male Wistar rats. The experimental group consisted of the animals that were exposed to hypoxia on day 14 of prenatal development, and the control group consisted of the animals that developed under the normal conditions. In the rats subjected to prenatal hypoxia, seizure episodes induced by weak currents in the range of 10-40 mA and their average duration were more pronounced as compared to the control animals.
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
authors.forename: D S
authors.initials: DS
authors.lastname: Kalinina
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Frolova
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Lavrentyeva
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.|St. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
authors.forename: N M
authors.initials: NM
authors.lastname: Dubrovskaya
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
authors.forename: N Ya
authors.initials: NY
authors.lastname: Lukomskaya
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
authors.forename: K Kh
authors.initials: KKh
authors.lastname: Kim
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia. aleksey_zaitsev@mail.ru.
authors.forename: A V
authors.initials: AV
authors.lastname: Zaitsev
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.|St. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
authors.forename: I A
authors.initials: IA
authors.lastname: Zhuravin
authors.affiliation: Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia. levmagazanik100@gmail.com.|St. Petersburg State University, St. Petersburg, Russia. levmagazanik100@gmail.com.
authors.forename: L G
authors.initials: LG
authors.lastname: Magazanik
mesh_terms: D000818:Animals; D004597:Electroshock; D004827:Epilepsy / Q000503:physiopathology*; D005260:Female; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D012640:Seizures / Q000503:physiopathology*