title: The Medusa Multi-Coil Versus Alternative Vascular Plugs for Iliac Artery Aneurysm Embolization (MVP-EMBO) Study.
abstract: Transcatheter embolization has evolved from the use of autologous clot as the embolic agent, to stainless-steel coils, to braided-nitinol vascular plugs. However, there are disadvantages to platinum and metal coils, including procedural time, radiation exposure, mass effect, risk of distal embolization, recanalization, imaging artifacts, and cost. Therefore, a large vessel-occluding device is needed to mitigate these current disadvantages. The Medusa Multi-Coil (MMC; EndoShape, Inc) is a Food and Drug Administration (FDA)-approved embolization device constructed primarily of radioopaque coils with synthetic fibers to promote thrombogenicity, and a unique delivery platform with both proximal and distal attachment to assist with precise placement. We report our experience with the endovascular treatment of internal iliac artery aneurysms using platinum coils vs MMCs.
authors.affiliation: Deborah Heart and Lung Center, 200 Trenton Road, Browns Mills, NJ 08015 USA. jcgeorgemd@gmail.com.
authors.forename: Jon C
authors.initials: JC
authors.lastname: George
authors.forename: Vincent
authors.initials: V
authors.lastname: Varghese
authors.forename: Richard
authors.initials: R
authors.lastname: Kovach
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys / Q000494:pharmacology; D057186:Comparative Effectiveness Research; D000072226:Computed Tomography Angiography / Q000379:methods; D004621:Embolization, Therapeutic / Q000295:instrumentation / Q000379:methods; D005260:Female; D006801:Humans; D017543:Iliac Aneurysm / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D010984:Platinum / Q000494:pharmacology; D011108:Polymers / Q000737:chemistry / Q000494:pharmacology; D011183:Postoperative Complications / Q000175:diagnosis*; D060489:Prosthesis Retention / Q000379:methods; D055989:Septal Occluder Device; D016896:Treatment Outcome
chemical_list: D000497:Alloys; D011108:Polymers; C013616:nitinol; D010984:Platinum