title: Imatinib-induced dental hyperpigmentation in chronic myeloid leukemia in an adult female.
abstract: The course of chronic myeloid leukemia (CML) has changed since the introduction of imatinib, and its side-effects are still being reported. We are reporting a case of a CML patient who presented to us with discoloration of the upper front teeth following 6 months of therapy with imatinib. On detailed evaluation, the patient was found to have imatinib-induced dental hyperpigmentation.
authors.affiliation: Department of Medicine, S N Medical College, Agra, Uttar Pradesh, India.
authors.forename: Prabhat
authors.initials: P
authors.lastname: Agrawal
authors.affiliation: Department of Medicine, S N Medical College, Agra, Uttar Pradesh, India.
authors.forename: Omkar
authors.initials: O
authors.lastname: Singh
authors.affiliation: Department of Medicine, S N Medical College, Agra, Uttar Pradesh, India.
authors.forename: Ashwini Kumar
authors.initials: AK
authors.lastname: Nigam
authors.affiliation: Department of Medicine, S N Medical College, Agra, Uttar Pradesh, India.
authors.forename: Shalini
authors.initials: S
authors.lastname: Upadhyay
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D000068877:Imatinib Mesylate / Q000009:adverse effects* / Q000627:therapeutic use; D015466:Leukemia, Myeloid, Chronic-Phase / Q000188:drug therapy; D047428:Protein Kinase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D014075:Tooth Discoloration / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D000068877:Imatinib Mesylate
keywords: Chronic myeloid leukemia; imatinib; tooth discoloration