title: Predicting technique and patient survival over 12 months in peritoneal dialysis: the role of anxiety and depression.
abstract: BACKGROUND
  Emotional distress is common in dialysis patients, but its role on clinical outcomes for patients on peritoneal dialysis (PD) is uncertain.
  
  
  OBJECTIVE
  To evaluate the effect of depression and anxiety on 1-year prognosis in PD patients.
  
  
  METHODS
  A total of N = 201 PD patients (58.9 ± 12.59 years) completed the Hospital Anxiety Depression Scale and measures of social support at baseline and were followed up for CC technique and actuarial patient survival.
  
  
  RESULTS
  Mortality and technique failure rates were 9.9 and 5.97 %, respectively. Carer-assisted PD, anxiety, comorbid burden and albumin were significant univariate predictors. Multivariate proportional hazard model to adjust for confounders indicated that anxiety remained significant with HR of 2.145 [95 % CI 1.03, 4.49, p = 0.043] for death/technique failure.
  
  
  CONCLUSIONS
  Anxiety is an important predictor of actuarial and technique survival in PD. Effective treatment for symptoms of anxiety may represent an easily achievable means of improving the clinical outcome of PD patients.
authors.affiliation: Department of Psychology, National University of Singapore, Block AS4, #02-28, 9 Arts Link, Singapore, 117570, Singapore. psygk@nus.edu.sg.|Health Services Research Group, City University London, London, UK. psygk@nus.edu.sg.
authors.forename: Konstadina
authors.initials: K
authors.lastname: Griva
authors.affiliation: Department of Psychology, National University of Singapore, Block AS4, #02-28, 9 Arts Link, Singapore, 117570, Singapore.
authors.forename: Augustine W C
authors.initials: AW
authors.lastname: Kang
authors.affiliation: Department of Psychology, National University of Singapore, Block AS4, #02-28, 9 Arts Link, Singapore, 117570, Singapore.
authors.forename: Zhen Li
authors.initials: ZL
authors.lastname: Yu
authors.affiliation: Department of Psychology, National University of Singapore, Block AS4, #02-28, 9 Arts Link, Singapore, 117570, Singapore.
authors.forename: Vanessa Y W
authors.initials: VY
authors.lastname: Lee
authors.affiliation: Department of Physiology, Faculty of Medicine, University of Thessaly, Karditsa, Greece.
authors.forename: Sotiris
authors.initials: S
authors.lastname: Zarogianis
authors.affiliation: Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore.
authors.forename: Moong Chen
authors.initials: MC
authors.lastname: Chan
authors.affiliation: Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore.
authors.forename: Marjorie
authors.initials: M
authors.lastname: Foo
mesh_terms: D000206:Actuarial Analysis; D000368:Aged; D001007:Anxiety / Q000209:etiology*; D003863:Depression / Q000209:etiology*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000523:psychology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000523:psychology*; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D012944:Social Support; D015996:Survival Rate
keywords: Anxiety; Clinical outcomes; Depression; Peritoneal dialysis; Technique and patient survival