title: Regulation of nuclear morphology by actomyosin components and cell geometry.
abstract: Extracellular microenvironmental signals modulate the coupling between cytoskeleton to nuclear links to regulate gene expression profiles. However the influence of actomyosin assembly on the morphology of the nucleus is not well understood. In this paper, we quantitatively demonstrate the role of cell geometry and specific actomyosin molecular components in their control of nuclear morphology.
authors.forename: Nisha M
authors.initials: NM
authors.lastname: Ramdas
authors.forename: Qingsen
authors.initials: Q
authors.lastname: Li
authors.forename: G V
authors.initials: GV
authors.lastname: Shivashankar
mesh_terms: D000199:Actins / Q000235:genetics / Q000378:metabolism / Q000648:ultrastructure; D000205:Actomyosin / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure; D002478:Cells, Cultured; D003599:Cytoskeleton / Q000378:metabolism; D004330:Drosophila / Q000166:cytology; D007091:Image Processing, Computer-Assisted; D051379:Mice; D057054:Molecular Imaging; D041681:NIH 3T3 Cells / Q000166:cytology; D034622:RNA Interference
chemical_list: D000199:Actins; D000205:Actomyosin