title: [Anti-rotavirus and intussusception: no evidence to discontinue the universal vaccination policy].
abstract: This report analyses the serious side effects of rotavirus vaccine with particular regard to intussusception, especially in light of the reasons which prompted the French health authorities to suspend, in April 2015, the previously approved recommendation of universal vaccination. Considering the current scientific evidence and the well motivated guidelines set by other European countries, the authors conclude that there are no reasons at the present time to suspend the universal offer of anti-rotavirus vaccination to infants, since it shows a favourable benefit-risk ratio and it is characterized by an excellent cost-effectiveness profile.
authors.affiliation: Dipartimento di Scienze della Salute, Università di Firenze, Italia.
authors.forename: Paolo
authors.initials: P
authors.lastname: Bonanni
authors.affiliation: Dipartimento SBIBIT, Università di Parma, Italia.
authors.forename: Carlo
authors.initials: C
authors.lastname: Signorelli
mesh_terms: D003362:Cost-Benefit Analysis; D005062:European Union; D019317:Evidence-Based Medicine; D006801:Humans; D007077:Ileal Diseases / Q000209:etiology; D007443:Intussusception; D007558:Italy; D032541:Mass Vaccination / Q000191:economics; D018570:Risk Assessment; D012400:Rotavirus Infections / Q000191:economics / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000008:administration & dosage* / Q000009:adverse effects / Q000191:economics
chemical_list: D022243:Rotavirus Vaccines