title: Analysis of serial CT images for studying the RT effects in head-neck cancer patients.
abstract: Images taken during and after RT for head and neck cancer have the potential to quantitatively assess xerostomia. Image information may be used as biomarkers of RT effects on parotid glands with significant potential to support adaptive treatment strategies. We investigated the possibility to extract information based on in-room CT images (kVCT, MVCT), acquired for daily image-guided radiotherapy treatment of head-and-neck cancer patients, in order to predict individual response in terms of toxicity. Follow-up MRI images were also used in order to investigate long term parotid gland deformation.
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Belli
authors.forename: Sara
authors.initials: S
authors.lastname: Broggi
authors.forename: Elisa
authors.initials: E
authors.lastname: Scalco
authors.forename: Giovanni Mauro
authors.initials: GM
authors.lastname: Cattaneo
authors.forename: Italo
authors.initials: I
authors.lastname: Dell'Oca
authors.forename: Gerlinde
authors.initials: G
authors.lastname: Logghe
authors.forename: Stefano
authors.initials: S
authors.lastname: Moriconi
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Sanguineti
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Valentini
authors.forename: Nadia
authors.initials: N
authors.lastname: Di Muzio
authors.forename: Claudio
authors.initials: C
authors.lastname: Fiorino
authors.forename: Riccardo
authors.initials: R
authors.lastname: Calandrino
mesh_terms: D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D010306:Parotid Gland / Q000000981:diagnostic imaging* / Q000528:radiation effects*; D061089:Radiotherapy, Image-Guided / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014987:Xerostomia / Q000000981:diagnostic imaging*