title: Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling.
abstract: In this case report, we describe a refractory CMML case without eosinophilia harboring a PDGFRB rearrangement leading to a favorable response with imatinib. We believe this case demonstrates the utility of broad spectrum genomic profiling in refractory CMML cases as an opportunity to uncover additional treatment options.
authors.affiliation: DeBartolo Family Personalized Medicine Institute, H. Lee Moffitt Cancer and Research Institute, Tampa, FL, United States ; Department of Population Sciences, H. Lee Moffitt Cancer and Research Institute, Tampa, FL, United States.
authors.forename: Gillian C
authors.initials: GC
authors.lastname: Bell
authors.affiliation: Department of Hematologic Malignancies and Immunology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States.
authors.forename: Eric
authors.initials: E
authors.lastname: Padron