title: Metastatic lung adenocarcinoma related α-Fetoprotein elevation in a patient with HBV-related cirrhosis.
abstract: HCC is the most common type of primary liver tumor. The Practice Guideline, AASLD, for HCC recommended surveillance of HBV carriers at high risk of HCC with US every 6-12 months. Laboratory surveillance option is the measurement of serum α-fetoprotein level which has long been used for the diagnosis of HCC. But, increased serum levels of α-fetoprotein are also seen in acute hepatitis, cirrhosis, and malignancies include yolk sac carcinoma, neuroblastoma, hepatoblastoma, gastric and lung carcinoma. Because of elevation α-fetoprotein in these malignancies, liver mass with an elevated α-fetoprotein does not directly indicate HCC. For these reason, clinicians evaluating patient with liver mass and HBV-related cirrhosis should be vigilant for other case of α-fetoprotein elevation.
authors.forename: Mevlut
authors.initials: M
authors.lastname: Hamamci
authors.forename: Fatih
authors.initials: F
authors.lastname: Karaahmet
authors.forename: Hakan
authors.initials: H
authors.lastname: Akinci
authors.forename: Serta
authors.initials: S
authors.lastname: Kilincalp
authors.forename: Ruchan
authors.initials: R
authors.lastname: Acıkgoz
authors.forename: Sahin
authors.initials: S
authors.lastname: Coban
authors.forename: Ilhami
authors.initials: I
authors.lastname: Yuksel
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism / Q000556:secondary*; D000077192:Adenocarcinoma of Lung; D000368:Aged; D019694:Hepatitis B, Chronic / Q000150:complications / Q000378:metabolism*; D006801:Humans; D008103:Liver Cirrhosis / Q000378:metabolism* / Q000821:virology*; D008113:Liver Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000556:secondary*; D008175:Lung Neoplasms / Q000378:metabolism / Q000556:secondary*; D008297:Male; D000509:alpha-Fetoproteins / Q000378:metabolism*
chemical_list: D000509:alpha-Fetoproteins