title: A population-based study of the epidemiology of pancreatic cancer: a brief report.
abstract: OBJECTIVE
  Administrative data are used to describe the pancreatic cancer (pcc) population. The analysis examines demographic details, incidence, site, survival, and factors influencing mortality in a cohort of individuals diagnosed with pcc.
  
  
  METHODS
  Incident cases of pcc diagnosed in Ontario between 1 January 2004 and 31 December 2011 were extracted from the Ontario Cancer Registry. They were linked by encrypted health card number to several administrative databases to obtain demographic and mortality information. Descriptive, bivariate, and survival analyses were conducted.
  
  
  RESULTS
  During the period of interest, 9221 new cases of pcc (4548 in men, 4673 in women) were diagnosed, for an age-adjusted standardized annual incidence in the range of 8.6-9.5 per 100,000 population. Mean age at diagnosis was 70.3 ± 12.5 years (standard deviation). Five-year survival was 7.2% (12.8% for those <60 years of age and 3.6% for those >80 years of age). Survival varied by sex, older age, rural residence, lower income, site of involvement in the pancreas, and presence of comorbidity.
  
  
  CONCLUSIONS
  The mortality rate in pcc is exceptionally high. With an increasing incidence and a mortality positively associated with age, additional support will be needed for this highly fatal disease as demographics in Ontario continue to trend toward a higher proportion of older individuals.
authors.affiliation: Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
authors.forename: R S
authors.initials: RS
authors.lastname: Raju
authors.affiliation: Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
authors.forename: N
authors.initials: N
authors.lastname: Coburn
authors.affiliation: Institute for Clinical Evaluative Sciences, Toronto, ON;
authors.forename: N
authors.initials: N
authors.lastname: Liu
authors.affiliation: Institute for Clinical Evaluative Sciences, Toronto, ON;
authors.forename: J M
authors.initials: JM
authors.lastname: Porter
authors.affiliation: Health Outcomes and PharmacoEconomics Research Centre, Sunnybrook Research Institute, Toronto, ON;
authors.forename: S J
authors.initials: SJ
authors.lastname: Seung
authors.affiliation: Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
authors.forename: M C
authors.initials: MC
authors.lastname: Cheung
authors.affiliation: Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
authors.forename: N
authors.initials: N
authors.lastname: Goyert
authors.affiliation: Princess Margaret Cancer Centre, University Health Network, Toronto, ON;
authors.forename: N B
authors.initials: NB
authors.lastname: Leighl
authors.affiliation: Applied Research in Cancer Control, Cancer Care Ontario, Toronto, ON;
authors.forename: J S
authors.initials: JS
authors.lastname: Hoch
authors.affiliation: Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
authors.forename: M E
authors.initials: ME
authors.lastname: Trudeau
authors.affiliation: McMaster University, Hamilton, ON;
authors.forename: W K
authors.initials: WK
authors.lastname: Evans
authors.affiliation: Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON;
authors.forename: K N
authors.initials: KN
authors.lastname: Dainty
authors.affiliation: Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON;
authors.forename: C C
authors.initials: CC
authors.lastname: Earle
authors.affiliation: Health Outcomes and PharmacoEconomics Research Centre, Sunnybrook Research Institute, Toronto, ON; ; Department of Pharmacology, University of Toronto, Toronto, ON; ; International Centre for Health Innovation, Richard Ivey School of Business, Western University, London, ON.
authors.forename: N
authors.initials: N
authors.lastname: Mittmann
keywords: Pancreatic adenocarcinoma; outcomes; population studies; retrospective analyses