title: Possibility of Müller Cell Dysfunction as the Pathogenesis of Paclitaxel Maculopathy.
abstract: Cystoid macular edema (CME) without leakage is an adverse complication of paclitaxel administration in patients with cancer. However, the mechanism of non-leaking CME has been unclear. The authors report the case of a 66-year-old man who developed non-leaking CME during treatment with paclitaxel for gastric cancer. This case report suggests possible pathogenesis of paclitaxel-induced CME without evidence of leakage at angiography from the data of electroretinogram.
authors.forename: Shintaro
authors.initials: S
authors.lastname: Nakao
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ikeda
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Emi
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Ishibashi
mesh_terms: D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D002166:Camptothecin / Q000031:analogs & derivatives / Q000627:therapeutic use; D057915:Drug Substitution; D004596:Electroretinography; D063928:Ependymoglial Cells / Q000473:pathology*; D005451:Fluorescein Angiography; D006801:Humans; D000077146:Irinotecan; D008269:Macular Edema / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D017239:Paclitaxel / Q000009:adverse effects*; D013274:Stomach Neoplasms / Q000188:drug therapy; D041623:Tomography, Optical Coherence
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D000077146:Irinotecan; D017239:Paclitaxel; D002166:Camptothecin