title: Synthesis of inherently chiral calixarenes via direct mercuration of the partial cone conformation.
abstract: Direct mercuration of calix[4]arene immobilized in the partial cone conformation led to the meta-substituted isomer which was subsequently subjected to Pd-catalysed coupling (C-H activation) with the neighbouring aromatic subunit. Regioselective mercuration thus enabled access to a novel type of inherently chiral calixarenes with a highly distorted cavity potentially applicable to the design of new chiral receptors.
authors.affiliation: Department of Organic Chemistry, University of Chemistry and Technology Prague (UCTP), Technicka 5, 166 28, Prague 6, Czech Republic. lhotakp@vscht.cz.
authors.forename: Petr
authors.initials: P
authors.lastname: Slavík
authors.affiliation: Department of Organic Chemistry, University of Chemistry and Technology Prague (UCTP), Technicka 5, 166 28, Prague 6, Czech Republic. lhotakp@vscht.cz.
authors.forename: Michal
authors.initials: M
authors.lastname: Kohout
authors.affiliation: Department of Organic Chemistry, University of Chemistry and Technology Prague (UCTP), Technicka 5, 166 28, Prague 6, Czech Republic. lhotakp@vscht.cz.
authors.forename: Stanislav
authors.initials: S
authors.lastname: Böhm
authors.affiliation: Institute of Physics AS CR, v.v.i., Na Slovance 2, 182 21 Prague 8, Czech Republic. eignerv@vscht.cz.
authors.forename: Václav
authors.initials: V
authors.lastname: Eigner
authors.affiliation: Department of Organic Chemistry, University of Chemistry and Technology Prague (UCTP), Technicka 5, 166 28, Prague 6, Czech Republic. lhotakp@vscht.cz.
authors.forename: Pavel
authors.initials: P
authors.lastname: Lhoták