title: Ultrasonographic Evaluation of Optic Nerve Sheath Diameter among Healthy Chinese Adults.
abstract: The aim of the work described here was to establish the range for optic nerve sheath diameter (ONSD) and potential factors influencing ONSD in healthy Chinese adults. Both ONSDs were measured twice in the sagittal and transversal planes by two observers. The final ONSD value for each participant was the average of 16 measurements of both eyes. The ONSD range (N = 3680) among 230 participants was 2.65-4.30 mm. The upper ONSD limit was lower than those in previous studies in Caucasian and African samples. Simple linear regression analyses revealed that the ONSD was correlated with sex, body mass index and waistline and head circumference. After adjustment for potential confounds between these factors, sex (coefficient = 0.225, p < 0.001) and body mass index (coefficient = 0.042, p < 0.001) were independently associated with ONSD. Underweight women had the smallest ONSD. These results suggest that racial, sex, and body mass index differences should be noted when assessing ultrasonographic criteria.
authors.affiliation: Neuroscience Center, Department of Neurology, First Hospital of Jilin University, Jilin University, Changchun, China.
authors.forename: Lijuan
authors.initials: L
authors.lastname: Wang
authors.affiliation: Neuroscience Center, Department of Neurology, First Hospital of Jilin University, Jilin University, Changchun, China.
authors.forename: Liangshu
authors.initials: L
authors.lastname: Feng
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yao
authors.affiliation: Neuroscience Center, Department of Neurology, First Hospital of Jilin University, Jilin University, Changchun, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Deng
authors.affiliation: Neuroscience Center, Department of Neurology, First Hospital of Jilin University, Jilin University, Changchun, China.
authors.forename: Yuzhi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Neuroscience Center, Department of Neurology, First Hospital of Jilin University, Jilin University, Changchun, China. Electronic address: fengjcfrank@163.com.
authors.forename: Jiachun
authors.initials: J
authors.lastname: Feng
authors.affiliation: Neuroscience Center, Department of Neurology, First Hospital of Jilin University, Jilin University, Changchun, China.
authors.forename: Yingqi
authors.initials: Y
authors.lastname: Xing
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D009900:Optic Nerve / Q000000981:diagnostic imaging* / Q000502:physiology*; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D014463:Ultrasonography / Q000379:methods* / Q000706:statistics & numerical data; D055815:Young Adult
keywords: Cerebral pressure; Optic nerve sheath diameter; Ultrasonography