title: Outpatient Outcomes of Pediatric Patients with Left Ventricular Assist Devices.
abstract: Outpatient experience of children supported with continuous-flow ventricular assist devices (CF-VAD) is limited. We reviewed our experience with children discharged with CF-VAD support. All pediatric patients <18 years old with CF-VADs implanted at our institution were included. Discharge criteria included a stable medication regimen, completion of a VAD education program and standardized rehabilitation plan, and presence of a caregiver. Hospital readmissions (excluding scheduled admissions) were reviewed. Adverse events were defined by Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) criteria. Of 17 patients with CF-VADs, 8 (47%) were discharged from the hospital (1 HeartWare ventricular assist device (Heartware Inc., Framingham, MA), 7 HeartMate II (Thoratec Corp, Pleasanton, CA)). Median age was 15.3 (range 9.6-17.1) years and weight was 50.6 (33.6-141) kg. Device strategies were destination therapy (DT; n = 4) and bridge to transplant (n = 4). Patients spent a median 49 (26-107) days hospitalized postimplant and had 2 (1-5) hospital readmissions. Total support duration was 3,154 patient-days, with 2,413 as outpatient. Most frequent adverse events were device malfunction and arrhythmias. There was one death because of pump thrombosis and no bleeding or stroke events. Overall adverse event rate was 15.22 per 100 patient-months. Early experience suggests that children with CF-VADs can be safely discharged. Device malfunction and arrhythmia were the most common adverse events but were recognized quickly with structured outpatient surveillance.
authors.affiliation: From the *Division of Pediatric Cardiology, Stanford University, Palo Alto, California; †Lucile Packard Children's Hospital, Palo Alto, California; ‡Department of Pediatrics and Spectrum Child Health, Stanford University, Palo Alto, California; and §Department of Cardiothoracic Surgery, Stanford University, Palo Alto, California.
authors.forename: Sharon
authors.initials: S
authors.lastname: Chen
authors.forename: Aileen
authors.initials: A
authors.lastname: Lin
authors.forename: Esther
authors.initials: E
authors.lastname: Liu
authors.forename: Maryalice
authors.initials: M
authors.lastname: Gowan
authors.forename: Lindsay J
authors.initials: LJ
authors.lastname: May
authors.forename: Lan N
authors.initials: LN
authors.lastname: Doan
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Almond
authors.forename: Katsuhide
authors.initials: K
authors.lastname: Maeda
authors.forename: Olaf
authors.initials: O
authors.lastname: Reinhartz
authors.forename: Seth A
authors.initials: SA
authors.lastname: Hollander
authors.forename: David N
authors.initials: DN
authors.lastname: Rosenthal
mesh_terms: D000293:Adolescent; D002648:Child; D004868:Equipment Failure / Q000706:statistics & numerical data; D005260:Female; D006333:Heart Failure / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010045:Outpatients; D010359:Patient Readmission / Q000706:statistics & numerical data; D016896:Treatment Outcome