title: Influence of Thermal Treatment on the Antimicrobial Activity of Silver-Doped Biological Apatite.
abstract: In this paper, we report the structural and morphological properties of silver-doped hydroxyapatite (AgHAp) with a silver concentration x Ag = 0.5 before and after being thermal treated at 600 and 1000 °C. The results obtained by X-Ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and Raman spectroscopy suggest that the structure of the samples changes gradually, from hydroxyapatite (AgHAp_40) to a predominant β-TCP structure (AgHAp_1000), achieved when the thermal treatment temperature is 1000 °C. In the AgHAp_600 sample, the presence of two phases, HAp and β-TCP, was highlighted. Also, scanning electron microscopy studies suggest that the shape and dimension of the nanoparticles begin to change when the temperature increases. The antimicrobial activity of the obtained compounds was evaluated against Klebsiella pneumoniae, Staphylococcus aureus, and Candida albicans strains.
authors.affiliation: National Institute of Materials Physics, 105 bis Atomistilor Street, Măgurele, Romania.
authors.forename: Cristina Liana
authors.initials: CL
authors.lastname: Popa
authors.affiliation: National Institute of Materials Physics, 105 bis Atomistilor Street, Măgurele, Romania.
authors.forename: Carmen Steluta
authors.initials: CS
authors.lastname: Ciobanu
authors.affiliation: Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, 1-7 Polizu Street, Bucharest, Romania.
authors.forename: Georgeta
authors.initials: G
authors.lastname: Voicu
authors.affiliation: Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, 1-7 Polizu Street, Bucharest, Romania.
authors.forename: Eugenia
authors.initials: E
authors.lastname: Vasile
authors.affiliation: Microbiology Department, Faculty of Biology, University of Bucharest, Aleea Portocalelor 1-3, 60101, Bucharest, Romania.|Research Institute of the University of Bucharest-ICUB, Life, Environmental and Earth Sciences, Spl. Independentei 91-95, Bucharest, Romania.
authors.forename: Mariana Carmen
authors.initials: MC
authors.lastname: Chifiriuc
authors.affiliation: National Institute of Materials Physics, 105 bis Atomistilor Street, Măgurele, Romania.
authors.forename: Simona Liliana
authors.initials: SL
authors.lastname: Iconaru
authors.affiliation: National Institute of Materials Physics, 105 bis Atomistilor Street, Măgurele, Romania. dpredoi@gmail.com.
authors.forename: Daniela
authors.initials: D
authors.lastname: Predoi
keywords: Antimicrobial effect; Hydroxyapatite; Silver; Thermal treatment