title: Approaches by the US National Institutes of Health to support rigorous scientific research on dietary supplements and natural products.
abstract: Mechanistic, clinical, and epidemiological research relevant to dietary supplements (DS) is supported by the U.S. National Institutes of Health. The Office of Dietary Supplements and the National Center for Complementary and Integrative Health promote the development and appropriate use of rigorous and comprehensive DS analyses which are critical for research reproducibility, particularly when the investigational DS include chemically complex natural products with unclear mechanisms of action.
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., Bethesda, MD, 20892-7517, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Kuszak
authors.affiliation: Division of Extramural Research, National Center for Complementary and Integrative Health, National Institutes of Health, 6707 Democracy Blvd., Bethesda, MD, 20892, USA.
authors.forename: D C
authors.initials: DC
authors.lastname: Hopp
authors.affiliation: Division of Extramural Research, National Center for Complementary and Integrative Health, National Institutes of Health, 6707 Democracy Blvd., Bethesda, MD, 20892, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Williamson
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., Bethesda, MD, 20892-7517, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Betz
authors.affiliation: Office of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., Bethesda, MD, 20892-7517, USA.
authors.forename: B C
authors.identifier: http://orcid.org/0000-0001-8198-6921
authors.initials: BC
authors.lastname: Sorkin
mesh_terms: D001688:Biological Products / Q000032:analysis*; D019587:Dietary Supplements / Q000032:analysis*; D006801:Humans; D009316:National Institutes of Health (U.S.); D015203:Reproducibility of Results; D012107:Research Design; D014481:United States
chemical_list: D001688:Biological Products
keywords: National Institutes of Health; dietary supplements; natural products; research