title: Conducting polymer and its composite materials based electrochemical sensor for Nicotinamide Adenine Dinucleotide (NADH).
abstract: Nicotinamide Adenine Dinucleotide (NADH) is an important coenzyme in the human body that participates in many metabolic reactions. The impact of abnormal concentrations of NADH significantly causes different diseases in human body. Electrochemical detection of NADH using bare electrode is a challenging task especially in the presence of main electroactive interferences such as ascorbic acid (AA), uric acid (UA) and dopamine (DA). Modified electrodes have been widely explored to overcome the problems of poor sensitivity and selectivity occurred from bare electrodes. This review gives an overview on the progress of using conducting polymers, polyelectrolyte and its composites (co-polymer, carbonaceous, metal, metal oxide and clay) based modified electrodes for the sensing of NADH. In addition, developments on the fabrication of numerous conducting polymer composites based modified electrodes are clearly described.
authors.affiliation: Center for Ionics University of Malaya, Department of Physics, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.
authors.forename: Fatin Saiha
authors.initials: FS
authors.lastname: Omar
authors.affiliation: Center for Ionics University of Malaya, Department of Physics, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. Electronic address: naveennanoenergy@gmail.com.
authors.forename: Navaneethan
authors.initials: N
authors.lastname: Duraisamy
authors.affiliation: Center for Ionics University of Malaya, Department of Physics, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.
authors.forename: K
authors.initials: K
authors.lastname: Ramesh
authors.affiliation: Center for Ionics University of Malaya, Department of Physics, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. Electronic address: rameshtsubra@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Ramesh
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D004553:Electric Conductivity; D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods; D004566:Electrodes; D004867:Equipment Design; D006801:Humans; D008958:Models, Molecular; D009243:NAD / Q000032:analysis*; D011108:Polymers / Q000737:chemistry*
chemical_list: D011108:Polymers; D009243:NAD
keywords: Composite; Conducting polymer; Electrochemistry; NADH