title: Identification of Quantitative Trait Loci for the Phenolic Acid Contents and Their Association with Agronomic Traits in Tibetan Wild Barley.
abstract: Phenolic acids have been of considerable interest in human nutrition because of their strong antioxidative properties. However, even in a widely grown crop, such as barley, their genetic architecture is still unclear. In this study, genetic control of two main phenolic acids, ferulic acid (FA) and p-coumaric acid (p-CA), and their associations with agronomic traits were investigated among 134 Tibetan wild barley accessions. A genome-wide association study (GWAS) identified three DArT markers (bpb-2723, bpb-7199, and bpb-7273) associated with p-CA content and one marker (bpb-3653) associated with FA content in 2 consecutive years. The contents of the two phenolic acids were positively correlated with some agronomic traits, such as the first internode length, plant height, and some grain color parameters, and negatively correlated with the thousand-grain weight (TGW). This study provides DNA markers for barley breeding programs to improve the contents of phenolic acids.
authors.affiliation: Zhejiang Key Laboratory of Crop Germplasm, Department of Agronomy, Zhejiang University , Hangzhou, Zhejiang 310058, People's Republic of China.
authors.forename: Shengguan
authors.initials: S
authors.lastname: Cai
authors.affiliation: Zhejiang Key Laboratory of Crop Germplasm, Department of Agronomy, Zhejiang University , Hangzhou, Zhejiang 310058, People's Republic of China.
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Han
authors.affiliation: Zhejiang Key Laboratory of Crop Germplasm, Department of Agronomy, Zhejiang University , Hangzhou, Zhejiang 310058, People's Republic of China.
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Zhejiang Key Laboratory of Crop Germplasm, Department of Agronomy, Zhejiang University , Hangzhou, Zhejiang 310058, People's Republic of China.
authors.forename: Hongliang
authors.initials: H
authors.lastname: Hu
authors.affiliation: Zhejiang Key Laboratory of Crop Germplasm, Department of Agronomy, Zhejiang University , Hangzhou, Zhejiang 310058, People's Republic of China.
authors.forename: Fei
authors.initials: F
authors.lastname: Dai
authors.affiliation: Zhejiang Key Laboratory of Crop Germplasm, Department of Agronomy, Zhejiang University , Hangzhou, Zhejiang 310058, People's Republic of China.
authors.forename: Guoping
authors.initials: G
authors.lastname: Zhang
mesh_terms: D003373:Coumaric Acids / Q000032:analysis / Q000378:metabolism; D055106:Genome-Wide Association Study; D005838:Genotype; D001467:Hordeum / Q000737:chemistry / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D062385:Hydroxybenzoates / Q000032:analysis* / Q000378:metabolism; D011422:Propionates; D040641:Quantitative Trait Loci; D018609:Tibet
chemical_list: D003373:Coumaric Acids; D062385:Hydroxybenzoates; D011422:Propionates; C004999:ferulic acid; C017616:phenolic acid; C495469:p-coumaric acid
keywords: Tibetan wild barley; agronomic trait; ferulic acid (FA); genome-wide association study (GWAS); p-coumaric acid (p-CA)