title: Biochemical and Radiological Markers of Alzheimer's Disease Progression.
abstract: Alzheimer's disease (AD) is a neurodegenerative, inevitably progressive disease with a rate of cognitive, functional, and behavioral decline that varies highly from patient to patient. Although several clinical predictors of AD progression have been identified, to our mind in clinical practice there is a lack of a reliable biomarker that enables one to stratify the risk of deterioration. Identification of biomarkers that allow the monitoring of AD progression could change the way physicians and caregivers make treatment decisions. This review summarizes the results of studies on potential biochemical and radiological markers related to AD progression.
authors.affiliation: Department of Neurology, Jagiellonian University, Krakow, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Dziedzic
authors.affiliation: Department of Neurology, Jagiellonian University, Krakow, Poland.
authors.forename: Joanna
authors.initials: J
authors.lastname: Pera
authors.affiliation: Department of Neurology, Jagiellonian University, Krakow, Poland.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Klimkowicz-Mrowiec
authors.affiliation: Department of Neurodegeneration Diagnostics, Medical University of Białystok, Poland.|Department of Biochemical Diagnostics, University Hospital, Białystok, Poland.
authors.forename: Barbara
authors.initials: B
authors.lastname: Mroczko
authors.affiliation: Department of Neurology, Jagiellonian University, Krakow, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Slowik
mesh_terms: D000544:Alzheimer Disease / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D015415:Biomarkers / Q000378:metabolism*; D018450:Disease Progression; D006801:Humans; D059906:Neuroimaging; D011877:Radionuclide Imaging
chemical_list: D015415:Biomarkers
keywords: Alzheimer’s disease; biomarkers; cognitive decline; deterioration; progression