title: Famous.
abstract: A 62-year-old woman with multiple sclerosis experienced painless loss of vision in both eyes after starting fingolimod. Fundus examination revealed bilateral macular edema confirmed by optical coherence tomography. Fingolimod was discontinued, and a topical nonsteroidal inflammatory drug and corticosteroid were initiated. Within 2 months, vision returned to baseline with complete resolution of the macular edema.
authors.affiliation: Department of Ophthalmology, Duke Eye Center, Durham, North Carolina, USA.
authors.forename: Michelle J
authors.initials: MJ
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, Duke Eye Center, Durham, North Carolina, USA; Department of Neurology, Duke University Medical Center, Durham, North Carolina, USA. Electronic address: tariq.bhatti@duke.edu.
authors.forename: M Tariq
authors.initials: MT
authors.lastname: Bhatti
authors.affiliation: Department of Clinical Neurosciences, University of Calgary, Calgary, Canada; Department of Surgery, University of Calgary, Calgary, Canada.
authors.forename: Fiona
authors.initials: F
authors.lastname: Costello
mesh_terms: D005260:Female; D000068876:Fingolimod Hydrochloride / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D008266:Macula Lutea / Q000187:drug effects / Q000473:pathology*; D008269:Macular Edema / Q000139:chemically induced* / Q000175:diagnosis; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy*; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D007166:Immunosuppressive Agents; D000068876:Fingolimod Hydrochloride
keywords: disease-modifying agents; fingolimod; macular edema; multiple sclerosis; optic neuritis; sphingosine-1-phosphate