title: Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes against Mycobacterium tuberculosis.
abstract: A new series of quinoline hydrazone derivatives and their metal complexes have been synthesized and their biological properties have been evaluated against Mycobacterium tuberculosis (H37 RV strain). Most of the newly synthesized compounds displayed 100% inhibitory activity at a concentration of 6.25-25 μg/mL, against Mycobacterium tuberculosis. Fluorescence properties of all the synthesized compounds have been studied.
authors.affiliation: P.G. and Research Centre, Department of Chemistry, Government of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060, India.
authors.forename: Mustapha C
authors.initials: MC
authors.lastname: Mandewale
authors.affiliation: P.G. and Research Centre, Department of Chemistry, Government of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060, India.
authors.forename: Bapu
authors.initials: B
authors.lastname: Thorat
authors.affiliation: P.G. and Research Centre, Department of Chemistry, Government of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060, India.
authors.forename: Dnyaneshwar
authors.initials: D
authors.lastname: Shelke
authors.affiliation: Department of Chemistry, Chikitsak Samuha's Patkar-Varde College of Arts, Science and Commerce, Goregaon (West), Mumbai 400 062, India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Yamgar