title: Pyogenic spondylodiscitis following anti-interleukin-6 therapy in a patient with rheumatoid arthritis (implication of hematogenous infection risk in degenerative intervertebral discs): A case report and review of the literature.
authors.affiliation: Department of Orthopedic Surgery, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, Sapporo, 060-8638, Japan.
authors.forename: Takeru
authors.initials: T
authors.lastname: Tsujimoto
authors.affiliation: Department of Orthopedic Surgery, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, Sapporo, 060-8638, Japan. Electronic address: takamasa@med.hokudai.ac.jp.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Takahata
authors.affiliation: Department of Orthopedic Surgery, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, Sapporo, 060-8638, Japan.
authors.forename: Terufumi
authors.initials: T
authors.lastname: Kokabu
authors.affiliation: Hokkaido Medical Center for Rheumatic Diseases, Sapporo, 063-0811, Japan.
authors.forename: Megumi
authors.initials: M
authors.lastname: Matsuhashi
authors.affiliation: Department of Orthopedic Surgery, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, Sapporo, 060-8638, Japan.
authors.forename: Norimasa
authors.initials: N
authors.lastname: Iwasaki
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods; D015299:Discitis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000000981:diagnostic imaging* / Q000209:etiology; D008279:Magnetic Resonance Imaging / Q000379:methods; D018570:Risk Assessment; D013166:Spondylitis / Q000000981:diagnostic imaging / Q000628:therapy; D016896:Treatment Outcome; D000093242:Interleukin-6 Inhibitors
chemical_list: D000900:Anti-Bacterial Agents; D061067:Antibodies, Monoclonal, Humanized; D000093242:Interleukin-6 Inhibitors; C502936:tocilizumab