title: Repeated early thrombolysis in cervical spinal cord ischemia.
abstract: Specific therapy of acute spinal ischemia is not established. We report the first case of an MRI-verified cervical spinal ischemia treated by thrombolysis and review the literature. A 72-year old woman with right-sided motor hemiparesis and trunk ataxia was treated by intravenous thrombolysis with full recovery. Three days later she developed again a severe right-sided sensorimotor hemiparesis and a second off-label intravenous thrombolysis was repeated. Magnetic resonance imaging revealed a right-sided posterior-lateral cervical spinal ischemia. Spinal ischemia may clinically present with a cerebral-stroke-like picture challenging diagnostic and therapeutic procedure. Systemic thrombolysis might be a treatment option in acute spinal ischemia. In addition, early repeated systemic thrombolysis may be considered in selected strokes.
authors.affiliation: Department of Neurology, kbo-Inn-Salzach-Klinikum, Gabersee 7, 83512, Wasserburg am Inn, Germany. thorleif.etgen@kbo.de.|Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany. thorleif.etgen@kbo.de.
authors.forename: Thorleif
authors.initials: T
authors.lastname: Etgen
authors.affiliation: Department of Neurology, Kliniken Südostbayern - Klinikum Traunstein, Traunstein, Germany.
authors.forename: Constanze
authors.initials: C
authors.lastname: Höcherl
mesh_terms: D000368:Aged; D001259:Ataxia / Q000188:drug therapy; D066193:Cervical Cord / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D010291:Paresis / Q000188:drug therapy; D012008:Recurrence; D055502:Secondary Prevention; D015912:Thrombolytic Therapy / Q000379:methods*
keywords: Magnetic resonance imaging; Spinal ischemia; Stroke; Thrombolysis