title: The Vitiligo Impact Patient Scale (VIPs): Development and Validation of a Vitiligo Burden Assessment Tool.
abstract: Vitiligo has a major impact on health-related quality of life. Although a few vitiligo-specific quality of life instruments exist, there is no specific vitiligo burden tool. We developed and validated a specific vitiligo burden tool according to skin phototype. In total, 301 patients completed 35 items of the Vitiligo Impact Patient scale, of whom 235 were of skin phototype I to III and 66 of phototype IV to VI. The dimensionality of the items was evaluated using factor analyses, with results suggesting three factors in fair- and dark-skinned patients ("Psychological effects on daily life," "Relationships and Sexuality," and "Economic Constraints, Care & Management of Disease"). Unidimensionality was confirmed by higher order factor analysis. Cronbach's α were high-and intradimensional coherences all demonstrated good reliability (α > 0.8). The final instrument consists of 29 items (19 items common to all patients, 3 specific to fair skin, and 7 to dark skin). The test-retest reliability demonstrated very good reproducibility. The intraclass correlation of each dimension was greater than 0.90 for each population. External validity was confirmed by the correlation coefficients and Bland and Altman plots of the Vitiligo Impact Patient scale-Fair Skin and Vitiligo Impact Patient scale-Dark Skin versus the Short-Form-12, PVC Metra, Body Image States Scale, and Daily Life Quality Index assessment tools.
authors.affiliation: Department of Dermatology and Pediatric Dermatology, National Reference Center for Rare Skin Disorders, Pellegrin Children's Hospital, Bordeaux, France.
authors.forename: Camille
authors.initials: C
authors.lastname: Salzes
authors.affiliation: Biostatistics, Qualees, Paris, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Abadie
authors.affiliation: Department of Dermatology and Pediatric Dermatology, National Reference Center for Rare Skin Disorders, Pellegrin Children's Hospital, Bordeaux, France; Patient support Group, Association Française du Vitiligo (AFV), INSERM U1035, Bordeaux Segalen University, Bordeaux, France.
authors.forename: Julien
authors.initials: J
authors.lastname: Seneschal
authors.affiliation: Centre of Evidence Based Dermatology, University of Nottingham, Kings Meadow Campus, Lenton Lane, Nottingham, United Kingdom.
authors.forename: Maxine
authors.initials: M
authors.lastname: Whitton
authors.affiliation: Association Française du Vitiligo, Paris, France.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Meurant
authors.affiliation: Department of Dermatology, Centre Hospitalier De Pau, Pau, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Jouary
authors.affiliation: Department of Dermatology and Pediatric Dermatology, National Reference Center for Rare Skin Disorders, Pellegrin Children's Hospital, Bordeaux, France.
authors.forename: Fabienne
authors.initials: F
authors.lastname: Ballanger
authors.affiliation: Department of Dermatology and Pediatric Dermatology, National Reference Center for Rare Skin Disorders, Pellegrin Children's Hospital, Bordeaux, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Boralevi
authors.affiliation: Department of Dermatology and Pediatric Dermatology, National Reference Center for Rare Skin Disorders, Pellegrin Children's Hospital, Bordeaux, France; Patient support Group, Association Française du Vitiligo (AFV), INSERM U1035, Bordeaux Segalen University, Bordeaux, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Taieb
authors.affiliation: Impact Daily Of Life (IDOL), EMMA, Vincennes, France.
authors.forename: Charles
authors.initials: C
authors.lastname: Taieb
authors.affiliation: Department of Dermatology and Pediatric Dermatology, National Reference Center for Rare Skin Disorders, Pellegrin Children's Hospital, Bordeaux, France; Patient support Group, Association Française du Vitiligo (AFV), INSERM U1035, Bordeaux Segalen University, Bordeaux, France. Electronic address: khaled.ezzedine@chu-bordeaux.fr.
authors.forename: Khaled
authors.initials: K
authors.lastname: Ezzedine
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors; D018434:Sickness Impact Profile; D013315:Stress, Psychological; D011795:Surveys and Questionnaires; D014820:Vitiligo / Q000175:diagnosis / Q000523:psychology*