title: A case of delayed respiratory depression caused by accidental subcutaneous opioid infusion.
abstract: We report a case of delayed respiratory depression due to accidental subcutaneous opioid infusion. A healthy 33-year-old woman underwent orthopedic surgery under general anesthesia. Before the end of the operation, it was noticed that a part of the opioid infusion had been administered subcutaneously. About 15 min after tracheal extubation, the patient developed respiratory depression and loss of consciousness. The patient recovered with the use of jaw lift together with bag-valve-mask ventilation. We believe that accidental subcutaneous opioid accumulation may have caused the respiratory depression.
authors.affiliation: Division of Anesthesiology, Department of Surgery Related, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe City, 650-0017, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Okada
authors.affiliation: Division of Anesthesiology, Department of Surgery Related, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe City, 650-0017, Japan. moriori@tg8.so-net.ne.jp.
authors.forename: Moritoki
authors.initials: M
authors.lastname: Egi
authors.affiliation: Division of Anesthesiology, Department of Surgery Related, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe City, 650-0017, Japan.
authors.forename: Hitoaki
authors.initials: H
authors.lastname: Sato
authors.affiliation: Division of Anesthesiology, Department of Surgery Related, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe City, 650-0017, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Nomura
authors.affiliation: Division of Anesthesiology, Department of Surgery Related, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe City, 650-0017, Japan.
authors.forename: Masako
authors.initials: M
authors.lastname: Okada
authors.affiliation: Division of Anesthesiology, Department of Surgery Related, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe City, 650-0017, Japan.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Izuta
authors.affiliation: Division of Anesthesiology, Department of Surgery Related, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe City, 650-0017, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Mizobuchi
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000009:adverse effects*; D000768:Anesthesia, General / Q000379:methods; D003243:Consciousness; D005260:Female; D006801:Humans; D012131:Respiratory Insufficiency / Q000139:chemically induced*
chemical_list: D000701:Analgesics, Opioid
keywords: Delayed respiratory depression; Opioid; Subcutaneous infusion