title: Autoantibody-mediated encephalitis: Not just paraneoplastic, not just limbic, and not untreatable.
abstract: Autoantibody-mediated encephalitis is a heterogeneous group of recently identified disorders, all caused by autoimmunity directed against components of the central nervous system. Despite severe and even prolonged neurologic deficits, dramatic improvements may occur with aggressive treatment.
authors.affiliation: Neurohospitalist Program, Department of Specialty Medicine, Aultman Hospital, Canton, OH, USA. E-mail: Adham.Jammoul@aultman.com.
authors.forename: Adham
authors.initials: A
authors.lastname: Jammoul
authors.affiliation: Neuromuscular Center, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Yuebing
authors.initials: Y
authors.lastname: Li
authors.affiliation: Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.|Clinical Associate Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Rae-Grant
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000097:blood*; D001933:Brain Stem; D002531:Cerebellum; D004660:Encephalitis / Q000175:diagnosis* / Q000276:immunology* / Q000628:therapy; D005260:Female; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D020363:Limbic Encephalitis / Q000276:immunology; D020361:Paraneoplastic Syndromes, Nervous System / Q000175:diagnosis / Q000276:immunology*; D049268:Positron-Emission Tomography; D024642:Potassium Channels, Voltage-Gated / Q000276:immunology; D011506:Proteins / Q000276:immunology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology
chemical_list: D001323:Autoantibodies; D047908:Intracellular Signaling Peptides and Proteins; C116499:LGI1 protein, human; D024642:Potassium Channels, Voltage-Gated; D011506:Proteins; D016194:Receptors, N-Methyl-D-Aspartate