title: Effect of Subgingival Irrigation with Different Substances in the Treatment of Periodontal Disease. A Histometric Study in Rats.
abstract: The aim of this study was to evaluate the histometric effects of subgingival irrigation with different solutions as adjuvant for the treatment of periodontal disease in rats. Periodontal disease was induced by ligature in the first lower molars of 91 Wistar rats over the course of 28 days. After removal of the ligatures, the animals were subjected to scaling and root planing, followed by subgingival irrigation with different solutions (0.9% saline, 0.2% chlorhexidine, 0.1% and 0.5% sodium hypochlorite and 11% propolis extract). The animals were sacrificed 7 and 14 days after the treatment and tissue was processed for histometric analysis for evaluation of bone support and epithelial migration. The histometric analysis showed no statistically significant differences between the group treated with scaling and groups treated with subgingival irrigation (p > 0.05) regarding bone support and epithelial migration. Similarly, significant differences were not found among the different solutions used for subgingival irrigation. This study agrees with the position of the American Academy of Periodontology, which states that there is insufficient evidence to indicate the routine use of subgingival irrigation as adjuvant to periodontal treatment.
authors.affiliation: Department of Dentistry II, School of Dentistry at São Luís, Maranhão Federal University, São Luís, Maranhão, Brazil. claudiovanucci@hotmail.com.br.
authors.forename: Claudio Vanucci Silva
authors.initials: CV
authors.lastname: de Freitas
authors.affiliation: Department of Dentistry II, School of Dentistry at São Luís, Maranhão Federal University, São Luís, Maranhão, Brazil.
authors.forename: Larissa Paula Vieira
authors.initials: LP
authors.lastname: Galdez
authors.affiliation: Department of Biology, Health Science Center, Maranhão Federal University, São Luís, Maranhão, Brazil.
authors.forename: Hugo Leonardo Melo
authors.initials: HL
authors.lastname: Dias
authors.affiliation: Department of Diagnostic and Surgery, School of Dentistry at Araraquara, São Paulo State University, Araraquara, São Paulo, Brazil.
authors.forename: Joni Augusto
authors.initials: JA
authors.lastname: Cirelli
authors.affiliation: Department of Dentistry II, School of Dentistry at São Luís, Maranhão Federal University, São Luís, Maranhão, Brazil.
authors.forename: Erick Miranda
authors.initials: EM
authors.lastname: Souza
authors.affiliation: Department of Dentistry II, School of Dentistry at São Luís, Maranhão Federal University, São Luís, Maranhão, Brazil. claudiovanucci@hotmail.com.br.
authors.forename: Vanessa Camila Silva
authors.initials: VC
authors.lastname: da Silva
mesh_terms: D000818:Animals; D002710:Chlorhexidine / Q000627:therapeutic use; D012534:Dental Scaling; D010510:Periodontal Diseases / Q000188:drug therapy; D010514:Periodontal Pocket / Q000188:drug therapy; D051381:Rats; D017208:Rats, Wistar; D016745:Root Planing; D007507:Therapeutic Irrigation
chemical_list: D002710:Chlorhexidine
keywords: chlorhexidine; periodontal diseases; propolis; sodium hypochlorite; therapeutic irrigation