title: Retrospective Clinical Study of Eighty-One Cases of Intracranial Mucormycosis.
abstract: BACKGROUND
  Fungal infections of the central nervous system, especially cerebral mucormycosis or brain abscess are very rare.Cerebral mucormycosis is a rare disease. It is not an independent disease, but a secondary opportunistic infectious disease.
  
  
  METHODS
  This study has collected the data of 81 cases of intracranial mucormycosis from 28 Chinese hospitals, within 37 years, as well as reviewed the literatures and retrospectively analyzed and summarized this disease's background, clinical classifications, risk factors, pathology, clinical manifestations, diagnosis, treatment, and prognosis.
  
  
  RESULTS
  The 81 IM cases were aged between 15 days (the youngest) and 79 years (oldest), with a mean age of 41.6 years. Among them, 12 cases were <1 year old (the infant group), six cases were within one to 13 years old (the children group), and 63 cases were >14 years old (the adult group ). 45 cases were male and 36 were female, with a male/female ratio of 1.25:1.0. The shortest duration of the disease was three days, and the longest was 248 days.
  
  
  CONCLUSIONS
  This study helped to realize an early diagnosis and treatment, improve the cure rate, and reduce mortality.
authors.affiliation: Department of Neurosurgery, First Central Hospital, No 24 Fukang Road, Nankai, Tianjin, China.
authors.forename: Jinjian
authors.initials: J
authors.lastname: Ma
authors.affiliation: Department of Neurosurgery, First Central Hospital, No 24 Fukang Road, Nankai, Tianjin, China.
authors.forename: Ruichao
authors.initials: R
authors.lastname: Jia
authors.affiliation: Department of Neurosurgery, First Central Hospital, No 24 Fukang Road, Nankai, Tianjin, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, First Central Hospital, No 24 Fukang Road, Nankai, Tianjin, China.
authors.forename: Yunyang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Hematology, First Central Hospital, No 24 Fukang Road, Nankai, Tianjin, China.
authors.forename: Yuming
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, First Central Hospital, No 24 Fukang Road, Nankai, Tianjin, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Lin
authors.affiliation: Department of Pathology, First Central Hospital, No 24 Fukang Road, Nankai, Tianjin, China.
authors.forename: Mingmu
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, First Central Hospital, No 24 Fukang Road, Nankai, Tianjin, China.
authors.forename: Mu
authors.initials: M
authors.lastname: Li
keywords: Brain; intracalvarium; mucor