title: Distance regularized two level sets for segmentation of left and right ventricles from cine-MRI.
abstract: This paper presents a new level set method for segmentation of cardiac left and right ventricles. We extend the edge based distance regularized level set evolution (DRLSE) model in Li et al. (2010) to a two-level-set formulation, with the 0-level set and k-level set representing the endocardium and epicardium, respectively. The extraction of endocardium and epicardium is obtained as a result of the interactive curve evolution of the 0 and k level sets derived from the proposed variational level set formulation. The initialization of the level set function in the proposed two-level-set DRLSE model is generated from roughly located endocardium, which can be performed by applying the original DRLSE model. Experimental results have demonstrated the effectiveness of the proposed two-level-set DRLSE model.
authors.affiliation: College of Electronic Science and Engineering, Jilin University, Changchun, P. R. China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Institute of Cardiovascular Science, University College London, London, United Kingdom; The Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Captur
authors.affiliation: Institute of Cardiovascular Science, University College London, London, United Kingdom; The Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom.
authors.forename: James C
authors.initials: JC
authors.lastname: Moon
authors.affiliation: College of Electronic Science and Engineering, Jilin University, Changchun, P. R. China.
authors.forename: Shuxu
authors.initials: S
authors.lastname: Guo
authors.affiliation: School of Science, Nanjing University of Science and Technology, Nanjing, P. R. China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Yang
authors.affiliation: Institute of Digital Medicine, Third Military Medical University (TMMU), Chongqing, P. R. China. Electronic address: zhangcvh@aliyun.com.
authors.forename: Shaoxiang
authors.initials: S
authors.lastname: Zhang
authors.affiliation: School of Electronic Engineering, University of Electronic Science and Technology of China(UESTC), Chengdu, P. R. China. Electronic address: chunming.li@uestc.edu.cn.
authors.forename: Chunming
authors.initials: C
authors.lastname: Li
mesh_terms: D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*
keywords: Left and right ventricles; MRI; Segmentation; Two-level-set