title: A Retrospective Review of Treatment Failures Using Azithromycin and Doxycycline in the Treatment of Rectal Chlamydia Infections in Women and Men Who Have Sex With Men.
abstract: We examined the prevalence of rectal chlamydia treatment failures in men who have sex with men and women attending Alberta sexually transmitted infection clinics. Among those completing a test of cure, there was no significant difference among patients treated initially with azithromycin (treatment failure, 39/460 [8.5%]; 95% confidence interval, 5.9%-11.0%) compared with patients treated with doxycycline (0/16; 95% confidence interval, 0%-0.2%; P = 0.63).
authors.affiliation: From the *STI Services, Alberta Health Services, Edmonton, Canada; †STI Clinic, Alberta Health Services, Edmonton, Canada; ‡STI Clinic, Alberta Health Services, Calgary, Canada; §Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, Canada; and ¶Department of Medicine, University of Alberta, Edmonton, Canada.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Gratrix
authors.forename: Judith
authors.initials: J
authors.lastname: Brandley
authors.forename: Marla
authors.initials: M
authors.lastname: Dane
authors.forename: Sabrina S
authors.initials: SS
authors.lastname: Plitt
authors.forename: Petra
authors.initials: P
authors.lastname: Smyczek
authors.forename: Ron
authors.initials: R
authors.lastname: Read
authors.forename: Ameeta E
authors.initials: AE
authors.lastname: Singh
mesh_terms: D000328:Adult; D000416:Alberta; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017963:Azithromycin / Q000494:pharmacology*; D002690:Chlamydia Infections / Q000188:drug therapy*; D002692:Chlamydia trachomatis / Q000187:drug effects*; D004318:Doxycycline / Q000494:pharmacology*; D005260:Female; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D012002:Rectal Diseases / Q000188:drug therapy*; D012189:Retrospective Studies; D017211:Treatment Failure; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin; D004318:Doxycycline