title: Facial features in Harlequin ichthyosis: Clinical findings about 4 cases.
abstract: We report 4 cases of Harlequin ichthyosis, which is a rare and severe congenital ichthyosis involving the face. Facial appearance consists in severe ectropion, conjonctival edema, eclabium, flattened ears, broadened nose and large, thick, plate-like skin scales. Recent advances in neonatal care have been made, such as retinoid therapy, and have led to an increased survival rate. Early surgical correction of ectropion may be required because of ocular complications.
authors.affiliation: Service de chirurgie maxillo-faciale, hôpital Côte de Nacre, CHU de Caen, 14033 Caen cedex, France. Electronic address: jeandanielkun@yahoo.fr.
authors.forename: J-D
authors.initials: JD
authors.lastname: Kün-Darbois
authors.affiliation: Service d'anatomopathologie, hôpital Côte de Nacre, CHU de Caen, 14033 Caen cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Molin
authors.affiliation: Service d'anatomopathologie, hôpital Côte de Nacre, CHU de Caen, 14033 Caen cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Jeanne-Pasquier
authors.affiliation: Service de chirurgie maxillo-faciale, hôpital Côte de Nacre, CHU de Caen, 14033 Caen cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Paré
authors.affiliation: Service de chirurgie maxillo-faciale, hôpital Côte de Nacre, CHU de Caen, 14033 Caen cedex, France.
authors.forename: H
authors.initials: H
authors.lastname: Bénateau
authors.affiliation: Service de chirurgie maxillo-faciale, hôpital Côte de Nacre, CHU de Caen, 14033 Caen cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Veyssière
mesh_terms: D000328:Adult; D005145:Face / Q000473:pathology*; D005260:Female; D006801:Humans; D017490:Ichthyosis, Lamellar / Q000473:pathology*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D055815:Young Adult
keywords: Anomalies faciales; Congenital ichthyosis; Facial abnormalities; Fœtus Harlequin; Harlequin fetus; Ichtyose congénitale