title: Give it a REST!
abstract: The REST protein helps to prevent the premature activation of genes that are only expressed in mature neurons, and is now found to protect the genome of neural progenitor cells.
authors.affiliation: MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Pollard
authors.affiliation: MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
authors.forename: Maria Angeles
authors.initials: MA
authors.lastname: Marques-Torrejon
mesh_terms: D002454:Cell Differentiation; D016678:Genome; D058953:Neural Stem Cells / Q000378:metabolism; D055495:Neurogenesis / Q000235:genetics; D009474:Neurons / Q000378:metabolism*; D012097:Repressor Proteins / Q000378:metabolism*
chemical_list: D012097:Repressor Proteins
keywords: REST complex; developmental biology; genomic instability; knockout animals; mouse; neurogenesis; repression; stem cells; transcription factors