title: Persistent gross lipemia and suspected corneal lipidosis following intravenous lipid therapy in a cat with permethrin toxicosis.
abstract: OBJECTIVE
  To describe the observation of persistent gross lipemia and suspected corneal lipidosis following intravenous lipid therapy (IVLT) in a cat with permethrin toxicosis.
  
  
  METHODS
  A 5-year-old, spayed female, domestic short-haired cat with permethrin toxicosis was treated with a high dose of IVLT as an adjunct treatment when it remained severely obtunded following traditional supportive care. The cat received intravenous 20% lipid emulsion as a 1.5 mL/kg bolus given over 10 minutes followed by a constant rate infusion of 0.25 mL/kg/min for 2 hours. The cat developed gross lipemia that persisted at least 48 hours after the single dose of IVLT. Changes consistent with corneal lipidosis were observed and resolved within 1 week after IVLT.
  
  
  CONCLUSIONS
  This is the first report documenting the complications of persistent gross lipemia and suspected corneal lipidosis in a cat following IVLT. This report underscores the off-label, experimental nature of IVLT as a treatment for intoxication in cats.
authors.affiliation: Emergency Department, Red Bank Veterinary Hospital - Cherry Hill, Cherry Hill, NJ, 08108. marc.seitz@msstate.edu.
authors.forename: Marc A
authors.initials: MA
authors.lastname: Seitz
authors.affiliation: Emergency Department, Red Bank Veterinary Hospital - Cherry Hill, Cherry Hill, NJ, 08108.
authors.forename: Jamie M
authors.initials: JM
authors.lastname: Burkitt-Creedon
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D002415:Cats; D003315:Cornea / Q000473:pathology; D003937:Diagnosis, Differential; D005217:Fat Emulsions, Intravenous / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006949:Hyperlipidemias / Q000139:chemically induced / Q000175:diagnosis*; D007306:Insecticides / Q000506:poisoning*; D026023:Permethrin / Q000506:poisoning*; D011041:Poisoning / Q000175:diagnosis / Q000662:veterinary
chemical_list: D005217:Fat Emulsions, Intravenous; D007306:Insecticides; D026023:Permethrin
keywords: corneal opacity; feline; intralipid; pyrethroid; toxicity