title: Neonatal withdrawal syndrome and perinatal asphyxia. How to manage the patient? Case Report.
abstract: The aim of this work is to present the pitfalls of management of newborns with neonatal withdrawal syndrome (NWS) of different forms, which were complicated with the presence of severe perinatal asphyxia. The authors present some case reports of asphyxiated newborns of different gestational age with different forms of NWS. Prenatal and perinatal asphyxia determines the prognosis of future development of newborn. The combination of the asphyxia and NWS is stressful not only for the patient, but also for the physician. The most important step in management of this group of patients is to know the detailed mother's and patient's history and to perform detailed physical investigation. The optimal prenatal, perinatal and postnatal management with good cooperation between gynecologist and neonatologist can improve the quality of newborn's life. Care of newborn requires all the time teamwork.
authors.affiliation: Neonatal Department of Intensive Medicine, Faculty of Medicine, Comenius University in Bratislava and Children's Hospital in Bratislava, Slovakia.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Brucknerová
authors.affiliation: Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, Slovakia.
authors.forename: Mojmír
authors.initials: M
authors.lastname: Mach
authors.affiliation: Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, Slovakia.
authors.forename: Michal
authors.initials: M
authors.lastname: Dubovický
authors.affiliation: Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Bratislava, Slovakia.
authors.forename: Eduard
authors.initials: E
authors.lastname: Ujházy
mesh_terms: D001238:Asphyxia Neonatorum / Q000150:complications / Q000628:therapy*; D019468:Disease Management; D006801:Humans; D007231:Infant, Newborn; D008691:Methadone / Q000009:adverse effects; D009020:Morphine / Q000627:therapeutic use*; D009294:Narcotics / Q000009:adverse effects / Q000627:therapeutic use*; D009357:Neonatal Abstinence Syndrome / Q000188:drug therapy* / Q000209:etiology; D058850:Opiate Substitution Treatment / Q000009:adverse effects / Q000379:methods*
chemical_list: D009294:Narcotics; D009020:Morphine; D008691:Methadone