title: Comprehensive real-time epidemiological data from respiratory infections in Finland between 2010 and 2014 obtained from an automated and multianalyte mariPOC® respiratory pathogen test.
abstract: Respiratory viruses cause seasonal epidemics every year. Several respiratory pathogens are circulating simultaneously and typical symptoms of different respiratory infections are alike, meaning it is challenging to identify and diagnose different respiratory pathogens based on symptoms alone. mariPOC® is an automated, multianalyte antigen test which allows the rapid detection of nine respiratory infection pathogens [influenza A and B viruses, respiratory syncytial virus (RSV), human metapneumovirus, adenovirus, parainfluenza 1-3 viruses and pneumococci] from a single nasopharyngeal swab or aspirate samples, and, in addition, can be linked to laboratory information systems. During the study period from November 2010 to June 2014, a total of 22,485 multianalyte respi tests were performed in the 14 participating laboratories in Finland and, in total, 6897 positive analyte results were recorded. Of the tested samples, 25 % were positive for one respiratory pathogen, with RSV (9.8 %) and influenza A virus (7.2 %) being the most common findings, and 0.65 % of the samples were multivirus-positive. Only small geographical variations in seasonal epidemics occurred. Our results show that the mariPOC® multianalyte respi test allows simultaneous detection of several respiratory pathogens in real time. The results are reliable and give the clinician a picture of the current epidemiological situation, thus minimising guesswork.
authors.affiliation: Medical Microbiology and Immunology Unit, University of Turku, Kiinamyllynkatu 13, 20520, Turku, Finland. marianne.gunell@utu.fi.|TYKS-Sapa, Microbiology and Genetics Service Area, Microbiology Branch, Turku University Hospital, Turku, Finland. marianne.gunell@utu.fi.
authors.forename: M
authors.initials: M
authors.lastname: Gunell
authors.affiliation: ArcDia International Oy Ltd, Turku, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Antikainen
authors.affiliation: ArcDia International Oy Ltd, Turku, Finland.
authors.forename: N
authors.initials: N
authors.lastname: Porjo
authors.affiliation: Mehiläinen Private Health Care Center, Espoo, Helsinki, Oulu, Tampere, and Turku, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Irjala
authors.affiliation: Mehiläinen Private Health Care Center, Espoo, Helsinki, Oulu, Tampere, and Turku, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Vakkila
authors.affiliation: Mehiläinen Private Health Care Center, Espoo, Helsinki, Oulu, Tampere, and Turku, Finland.|Department of Clinical Chemistry, University of Helsinki, Helsinki, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Hotakainen
authors.affiliation: Vaasa Central Hospital, Vaasa, Finland.
authors.forename: S S
authors.initials: SS
authors.lastname: Kaukoranta
authors.affiliation: Vaasa Central Hospital, Vaasa, Finland.
authors.forename: J J
authors.initials: JJ
authors.lastname: Hirvonen
authors.affiliation: Seinäjoki Central Hospital, Seinäjoki, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Saha
authors.affiliation: SataDiag, Satakunta Central Hospital, Pori, Finland.
authors.forename: R
authors.initials: R
authors.lastname: Manninen
authors.affiliation: Carea, Kymenlaakso Social and Health Services, Kotka, Finland.
authors.forename: B
authors.initials: B
authors.lastname: Forsblom
authors.affiliation: TYKS-Sapa, Microbiology and Genetics Service Area, Microbiology Branch, Turku University Hospital, Turku, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Rantakokko-Jalava
authors.affiliation: Department of Pediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.
authors.forename: V
authors.initials: V
authors.lastname: Peltola
authors.affiliation: ArcDia International Oy Ltd, Turku, Finland.
authors.forename: J O
authors.initials: JO
authors.lastname: Koskinen
authors.affiliation: Medical Microbiology and Immunology Unit, University of Turku, Kiinamyllynkatu 13, 20520, Turku, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Huovinen
mesh_terms: D000956:Antigens, Viral / Q000276:immunology; D005387:Finland / Q000453:epidemiology; D005843:Geography; D049674:History, 21st Century; D006801:Humans; D007118:Immunoassay / Q000379:methods; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000266:history / Q000821:virology*; D012680:Sensitivity and Specificity; D014777:Virus Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000266:history / Q000821:virology
chemical_list: D000956:Antigens, Viral