title: Comparison of phenotypic tests for detecting BKC-1-producing Enterobacteriaceae isolates.
abstract: Carbapenemase-producing Enterobacteriaceae may exhibit in vitro susceptibility to carbapenems, especially those producing weak carbapenemases. Routine clinical laboratories have employed phenotypic tests for screening such isolates. BKC-1 is a recently reported carbapenemase that shows weak carbapenemase activity. In this study, we aimed to evaluate the behavior of distinct phenotypic methods against BKC-1-producing Enterobacteriaceae.
authors.affiliation: Laboratório Alerta, Division of Infectious Diseases, Department of Internal Medicine, Escola Paulista de Medicina/Universidade Federal de São Paulo, São Paulo, Brazil. Electronic address: willamesbrasileiro@hotmail.com.
authors.forename: Willames M B S
authors.initials: WM
authors.lastname: Martins
authors.affiliation: Laboratório Alerta, Division of Infectious Diseases, Department of Internal Medicine, Escola Paulista de Medicina/Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Jhonatha R
authors.initials: JR
authors.lastname: Cordeiro-Moura
authors.affiliation: Laboratório Alerta, Division of Infectious Diseases, Department of Internal Medicine, Escola Paulista de Medicina/Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Ana C
authors.initials: AC
authors.lastname: Ramos
authors.affiliation: Laboratório Alerta, Division of Infectious Diseases, Department of Internal Medicine, Escola Paulista de Medicina/Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Lorena C
authors.initials: LC
authors.lastname: Fehlberg
authors.affiliation: Laboratório Alerta, Division of Infectious Diseases, Department of Internal Medicine, Escola Paulista de Medicina/Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Adriana G
authors.initials: AG
authors.lastname: Nicoletti
authors.affiliation: Laboratório Alerta, Division of Infectious Diseases, Department of Internal Medicine, Escola Paulista de Medicina/Universidade Federal de São Paulo, São Paulo, Brazil.
authors.forename: Ana C
authors.initials: AC
authors.lastname: Gales
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics; D015780:Carbapenems / Q000378:metabolism / Q000494:pharmacology; D052978:Disk Diffusion Antimicrobial Tests; D004755:Enterobacteriaceae / Q000145:classification / Q000187:drug effects* / Q000201:enzymology* / Q000235:genetics; D006801:Humans; D006868:Hydrolysis; D008826:Microbial Sensitivity Tests / Q000379:methods; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D015780:Carbapenems; D001618:beta-Lactamases; C063912:carbapenemase
keywords: Antimicrobial resistance; BKC-1; Carbapenemase; Klebsiella pneumoniae