title: Cystatin C, a novel cardiometabolic risk marker in women with polycystic ovary syndrome.
abstract: OBJECTIVE
  To investigate the impact of urinary albumin excretion (UAE) and cystatin C on the metabolic components of polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Seventy-five women with PCOS were divided into two groups according to metabolic syndrome as MetS + and MetS-. Clinical, metabolic and renal parameters were compared between the groups. Correlation analyses were performed between cystatin C, microalbuminuria and clinical and metabolic parameters in women with PCOS.
  
  
  RESULTS
  Waist/hip ratio (WHR), body mass index, LDL cholesterol, triglyceride, total cholesterol, cystatin C, UAE were significantly higher in the MetS + group compared with the MetS - one. HDL cholesterol was significantly higher in the MetS - group than the MetS + one. The UAE positively correlates with LDL cholesterol, triglyceride and total cholesterol levels. Cystatin C positively correlates with UAE, WHR, LDL cholesterol, triglyceride, total cholesterol levels.
  
  
  CONCLUSIONS
  Evaluating UAE and cystatin C may be important for the detection of target subjects at high risk for future metabolic syndrome and cardiovascular disease.
authors.affiliation: a Department of Obstetrics and Gynecology , Marmara University , Istanbul , Turkey.
authors.forename: Aysegul
authors.initials: A
authors.lastname: Yildirim
authors.affiliation: a Department of Obstetrics and Gynecology , Marmara University , Istanbul , Turkey.
authors.forename: Begum
authors.initials: B
authors.lastname: Yildizhan
authors.affiliation: a Department of Obstetrics and Gynecology , Marmara University , Istanbul , Turkey.
authors.forename: Gokce
authors.initials: G
authors.lastname: Anik Ilhan
authors.affiliation: a Department of Obstetrics and Gynecology , Marmara University , Istanbul , Turkey.
authors.forename: Tanju
authors.initials: T
authors.lastname: Pekin
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood*; D055316:Cystatin C / Q000097:blood*; D005260:Female; D006801:Humans; D024821:Metabolic Syndrome / Q000097:blood* / Q000652:urine; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000652:urine; D055815:Young Adult
chemical_list: D015415:Biomarkers; D055316:Cystatin C
keywords: Cystatin C; metabolic syndrome; microalbuminuria; polycystic ovary syndrome; urinary albumin excretion