title: The prognostic role of EBER in pediatric cancer.
abstract: The Epstein-Barr virus (EBV) infection is an endemic disease, over 90% of the population being exposed to it by adulthood. EBV is implicated in the etiology of a significant number of neoplasms, which acquire particular features in terms of course and prognosis. Incidence rates are much higher in children. To establish the link between EBV and neoplasms, EBER (Epstein-Barr virus non-encoded RNAs) needs to be highlighted in tumor tissue. The role of EBV in patient response to oncological treatment remains controversial.
authors.affiliation: Department of Medical Oncology, "Prof. Dr. Ion Chiricuta" Oncological Institute, Cluj-Napoca, Romania; calincainap@yahoo.co.uk.
authors.forename: Simona Sorana
authors.initials: SS
authors.lastname: Căinap
authors.forename: Bogdan
authors.initials: B
authors.lastname: Fetică
authors.forename: Rareş
authors.initials: R
authors.lastname: Buiga
authors.forename: Călin
authors.initials: C
authors.lastname: Căinap
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Constantin
authors.forename: Alina Simona
authors.initials: AS
authors.lastname: Şovrea
mesh_terms: D002648:Child; D018572:Disease-Free Survival; D005260:Female; D004854:Herpesvirus 4, Human / Q000502:physiology*; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D009369:Neoplasms / Q000821:virology*; D011379:Prognosis; D012367:RNA, Viral / Q000378:metabolism*; D016896:Treatment Outcome
chemical_list: D012367:RNA, Viral