title: Fertility-sparing surgery in epithelial ovarian cancer.
abstract: Since the last two decades, the feasibility of fertility-sparing surgery in early-stage epithelial ovarian cancer has been explored by several teams. Despite the impossibility of conducting a randomized trial to validate this management, evidence-based data suggest that in selected cases, the preservation of the uterus and at least one part of the ovary does not lead to a high risk of relapse. Conservative surgery maintains organ function, enables patients of childbearing age to preserve their fertility and improves their quality of life. In this review, we analyze the main series in the literature on this topic in order to highlight the selected criteria for conservative management and to summarize oncological and fertility outcomes.
authors.affiliation: Service de Chirurgie Gynécologique, Gustave-Roussy, 114 Rue Edouard-Vaillant, 94805 Villejuif Cedex, France.
authors.forename: Enrica
authors.initials: E
authors.lastname: Bentivegna
authors.affiliation: Service de Chirurgie Gynécologique, Gustave-Roussy, 114 Rue Edouard-Vaillant, 94805 Villejuif Cedex, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Morice
authors.affiliation: Service de Chirurgie Gynécologique, Gustave-Roussy, 114 Rue Edouard-Vaillant, 94805 Villejuif Cedex, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Uzan
authors.affiliation: Service de Chirurgie Gynécologique, Gustave-Roussy, 114 Rue Edouard-Vaillant, 94805 Villejuif Cedex, France.
authors.forename: Sebastien
authors.initials: S
authors.lastname: Gouy
mesh_terms: D000077216:Carcinoma, Ovarian Epithelial; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D009367:Neoplasm Staging; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology / Q000601:surgery*; D059351:Organ Sparing Treatments; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome
keywords: conservative treatment; early stage; epithelial ovarian cancer; fertility-sparing surgery