title: First-in-man study of ACT-453859, a potent CRTH2 antagonist--Is the metabolite formation influenced by a polymorphic enzyme?
authors.affiliation: Suramus Bio, Drug Development, Bangalore, India.
authors.forename: Nuggehally R
authors.initials: NR
authors.lastname: Srinivas
mesh_terms: D000085:Acetates / Q000008:administration & dosage*; D002227:Carbazoles / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D011971:Receptors, Immunologic / Q000037:antagonists & inhibitors*; D011982:Receptors, Prostaglandin / Q000037:antagonists & inhibitors*
chemical_list: D000085:Acetates; D002227:Carbazoles; D011971:Receptors, Immunologic; D011982:Receptors, Prostaglandin