title: Magnetic resonance imaging for detection of depth of myometrial invasion and cervical invasion in patients with endometrial carcinoma.
abstract: OBJECTIVE
  The aim of this study was to evaluate clinical significance of depth of myometrial invasion and cervical invasion by magnetic resonance imaging (MRI) in patients with endometrial carcinoma.
  
  
  METHODS
  Between September 2011 and October 2014 on 98 patients who were diagnosed with and treated for endometrial carcinoma at Subei People's Hospital in China included in this study. Main outcome measure was the correlation between the depth of myometrial invasion and cervical invasion by preoperative MRI, transvaginal sonography, hysteroscopy with directed biopsy study and the subsequent histopathological findings following examination of the hysterectomy specimen.
  
  
  RESULTS
  The mean age was 54.6 years old and the most common histological subtype was the endometrioid type of endometrial adenocarcinoma (87.8%). In the evaluation of deep myometrial invasion (>50%), sensitivity, specificity, positive and negative predictive value and positive and negative likelihood ratios of MRI were 70.00%, 94.87%, 77.78%, 92.50%, 13.65, 0.316, respectively. For cervical invasion, these values were 72.73%, 98.85%, 88.89%, 96.63%, 63.27, 0.30, respectively.
  
  
  CONCLUSIONS
  MRI is the superior diagnostic method to detect the myometrial invasion and cervical invasion.
authors.affiliation: Department of Obstetrics and Gynecology, Clinical Medical College of Yangzhou University 98 W Nantong Rd, Yangzhou 225001, Jiangsu, China.
authors.forename: Xiang-Hua
authors.initials: XH
authors.lastname: Yin
authors.affiliation: Department of Obstetrics and Gynecology, Clinical Medical College of Yangzhou University 98 W Nantong Rd, Yangzhou 225001, Jiangsu, China.
authors.forename: Hong-Yan
authors.initials: HY
authors.lastname: Jia
authors.affiliation: Department of Obstetrics and Gynecology, Clinical Medical College of Yangzhou University 98 W Nantong Rd, Yangzhou 225001, Jiangsu, China.
authors.forename: Min
authors.initials: M
authors.lastname: Shi
authors.affiliation: Department of Obstetrics and Gynecology, Clinical Medical College of Yangzhou University 98 W Nantong Rd, Yangzhou 225001, Jiangsu, China.
authors.forename: Huan
authors.initials: H
authors.lastname: Wu
authors.affiliation: Department of Respiratory Medicine, Clinical Medical College of Yangzhou University 98 W Nantong Rd, Yangzhou 225001, Jiangsu, China.
authors.forename: Yun-Mo
authors.initials: YM
authors.lastname: Li
keywords: Endometrial carcinoma; MRI; cervical invasion; myometrial invasion