title: Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy.
abstract: We report the design of AIE fluorogen (AIEgen)-based multifunctional organic nanoparticles with surface siRNA decoration for targeted photodynamic therapy and RNA interference therapy.
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore. kai_li_cn@hotmail.com.
authors.forename: Guorui
authors.initials: G
authors.lastname: Jin
authors.affiliation: Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, 117585, Singapore. cheliub@nus.edu.sg.
authors.forename: Guangxue
authors.initials: G
authors.lastname: Feng
authors.affiliation: Department of Chemistry, Institute for Advanced Study, Institute of Molecular Functional Materials, Division of Biomedical Engineering, Division of Life Science, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Qin
authors.affiliation: Department of Chemistry, Institute for Advanced Study, Institute of Molecular Functional Materials, Division of Biomedical Engineering, Division of Life Science, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science & Technology, Clear Water Bay, Kowloon, Hong Kong, China and Guangdong Innovative Research Team, SCUT-HKUST Joint Research Laboratory, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Guangzhou, 510640, China.
authors.forename: Ben Zhong
authors.initials: BZ
authors.lastname: Tang
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore. kai_li_cn@hotmail.com and Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, 117585, Singapore. cheliub@nus.edu.sg.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore. kai_li_cn@hotmail.com.
authors.forename: Kai
authors.initials: K
authors.lastname: Li
mesh_terms: D053758:Nanoparticles; D009930:Organic Chemicals / Q000737:chemistry*; D010778:Photochemotherapy; D034622:RNA Interference
chemical_list: D009930:Organic Chemicals