title: Six-year follow-up of patients treated with oncoplastic reduction mammoplasty: A cohort study.
abstract: BACKGROUND
  Current evidence for the oncological safety of oncoplastic breast conservation is poor as it is based mostly on short-term follow-up data. Hence, we report long-term recurrence rates in patients treated with oncoplastic reduction mammoplasty (ORM).
  
  
  METHODS
  A prospectively maintained database was searched to identify patients who underwent ORM between 2005 and 2010. A retrospective review of medical records was carried out, including patients with ductal carcinoma in situ and invasive breast cancer.
  
  
  RESULTS
  Follow-up data from 65 consecutive patients with ORM were reviewed, of which 50 patients were eligible to measure long-term recurrence rates. The average weight of the resected tissue was 272 g altogether. The mean preoperative tumour size was 2.95 cm on imaging. 64% of patients had stage II - III cancers. Incomplete excision rate after ORM was 16.1%, completion mastectomy rate was 10.7%. During a median follow-up of 72 months, 2% local, 6% distant recurrence rates were detected. The breast cancer-specific survival rate was 96% per cent.
  
  
  CONCLUSIONS
  Based on these long-term follow-up data, ORM is an oncologically safe treatment option.
authors.affiliation: Department of Surgery, New Victoria Hospital, Glasgow, United Kingdom.
authors.forename: Syed A
authors.initials: SA
authors.lastname: Kabir
authors.affiliation: Department of Surgery, Western Infirmary, Glasgow, United Kingdom.
authors.forename: Sheila
authors.initials: S
authors.lastname: Stallard
authors.affiliation: Department of Plastic Surgery, Glasgow Royal Infirmary, United Kingdom.
authors.forename: Eva
authors.initials: E
authors.lastname: Weiler-Mithoff
authors.affiliation: Department of Plastic Surgery, Glasgow Royal Infirmary, United Kingdom.
authors.forename: James
authors.initials: J
authors.lastname: Mansell
authors.affiliation: Department of Pathology, South Glasgow University Hospital, United Kingdom.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Mallon
authors.affiliation: Department of Surgery, Western Infirmary, Glasgow, United Kingdom.
authors.forename: Julie C
authors.initials: JC
authors.lastname: Doughty
authors.affiliation: Department of Surgery, New Victoria Hospital, Glasgow, United Kingdom. Electronic address: Laszlo.Romics@glasgow.ac.uk.
authors.forename: Laszlo
authors.initials: L
authors.lastname: Romics
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000401:mortality / Q000473:pathology / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000401:mortality / Q000473:pathology / Q000601:surgery; D018275:Carcinoma, Lobular / Q000401:mortality / Q000473:pathology / Q000601:surgery; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D008408:Mastectomy / Q000706:statistics & numerical data; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D006113:United Kingdom / Q000453:epidemiology
keywords: Mammaplasty; Oncoplastic; Recurrence; Reduction