title: The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer.
abstract: The IASLC Staging and Prognostic Factors Committee has collected a new database of 94,708 cases donated from 35 sources in 16 countries around the globe. This has now been analysed by our statistical partners at Cancer Research And Biostatistics and, in close collaboration with the members of the committee proposals have been developed for the T, N, and M categories of the 8th edition of the TNM Classification for lung cancer due to be published late 2016. In this publication we describe the methods used to evaluate the resultant Stage groupings and the proposals put forward for the 8th edition.
authors.affiliation: Department of Thoracic Surgery, Royal Brompton and Harefield National Health Service Foundation Trust and Imperial College, London, United Kingdom. Electronic address: p.goldstraw@imperiaL.ac.uk.
authors.forename: Peter
authors.initials: P
authors.lastname: Goldstraw
authors.affiliation: Cancer Research and Biostatistics, Seattle, WA, USA.
authors.forename: Kari
authors.initials: K
authors.lastname: Chansky
authors.affiliation: Cancer Research and Biostatistics, Seattle, WA, USA.
authors.forename: John
authors.initials: J
authors.lastname: Crowley
authors.affiliation: Department of Thoracic Surgery, Hospital Universitari Mutua Terrassa, University of Barcelona, and CIBERES Lung Cancer Group, Terrassa, Barcelona, Spain.
authors.forename: Ramon
authors.initials: R
authors.lastname: Rami-Porta
authors.affiliation: Division of Thoracic Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Hisao
authors.initials: H
authors.lastname: Asamura
authors.affiliation: West German Cancer Centre, University Hospital, Ruhrlandklinik, University Duisburg-Essen, Essen, Germany.
authors.forename: Wilfried E E
authors.initials: WE
authors.lastname: Eberhardt
authors.affiliation: Department of Pathology, Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, United Kingdom.
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Nicholson
authors.affiliation: Queen's Cancer Research Institute, Kingston, ON, Canada.
authors.forename: Patti
authors.initials: P
authors.lastname: Groome
authors.affiliation: Cancer Research and Biostatistics, Seattle, WA, USA.
authors.forename: Alan
authors.initials: A
authors.lastname: Mitchell
authors.affiliation: Cancer Research and Biostatistics, Seattle, WA, USA.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Bolejack
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000145:classification* / Q000473:pathology*; D009367:Neoplasm Staging / Q000592:standards*; D011379:Prognosis; D018426:SEER Program
keywords: Lung cancer; Prognostic factors; Staging