title: Actin polymerisation after FCγR stimulation of human fibroblasts is BCL10 independent.
abstract: B-cell lymphoma 10 (BCL10) is not essential for actin polymerisation after FcγR stimulation in human fibroblasts.
authors.affiliation: Laboratory of Immunogenetics of Diseases, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain; Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: Sonia
authors.initials: S
authors.lastname: Garcia-Gomez
authors.affiliation: Immunology Unit, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: Rita
authors.initials: R
authors.lastname: Alvarez Doforno
authors.affiliation: St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY 10065, USA.
authors.forename: Rubén
authors.initials: R
authors.lastname: Martinez-Barricarte
authors.affiliation: Immunology Division, Vall d'Hebron University Hospital, Barcelona 08035, Spain.
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Torres
authors.affiliation: Immunology Unit, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Ferreira Cerdan
authors.affiliation: Laboratory of Immunogenetics of Diseases, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain; Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: Marian
authors.initials: M
authors.lastname: Davila
authors.affiliation: Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain; Laboratory of Tumour Immunology, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: Hernández-Jiménez
authors.affiliation: Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain; Laboratory of Tumour Immunology, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: Victor
authors.initials: V
authors.lastname: Toledano
authors.affiliation: Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain; Laboratory of Tumour Immunology, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: Carolina
authors.initials: C
authors.lastname: Cubillos-Zapata
authors.affiliation: Laboratory of Image and Immunohistochemistry, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: María Teresa
authors.initials: MT
authors.lastname: Vallejo-Cremades
authors.affiliation: Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain; Laboratory of Tumour Immunology, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: López-Collazo
authors.affiliation: Clinical Immunology Department, San Carlos Clinical Hospital, Madrid 28040, Spain.
authors.forename: Miguel
authors.initials: M
authors.lastname: Fernández Arquero
authors.affiliation: Clinical Immunology Department, San Carlos Clinical Hospital, Madrid 28040, Spain.
authors.forename: Silvia
authors.initials: S
authors.lastname: Sánchez-Ramón
authors.affiliation: St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY 10065, USA; Howard Hughes Medical Institute, New York, NY 10065, USA; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris 75015, France; University Paris Descartes, Imagine Institute, Paris 75015, France; Paediatric Haematology-Immunology Unit, Necker Hospital for Sick Children, Paris 75015, France.
authors.forename: Jean-Laurent
authors.initials: JL
authors.lastname: Casanova
authors.affiliation: Laboratory of Immunogenetics of Diseases, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain; Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz University Hospital, Madrid 28046, Spain. Electronic address: rebeca.perez@idipaz.es.
authors.forename: Rebeca
authors.initials: R
authors.lastname: Pérez de Diego
mesh_terms: D000199:Actins / Q000378:metabolism*; D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics* / Q000276:immunology; D000074018:B-Cell CLL-Lymphoma 10 Protein; D053468:CARD Signaling Adaptor Proteins / Q000276:immunology; D016022:Case-Control Studies; D020169:Caspases / Q000276:immunology; D005347:Fibroblasts / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D008856:Microscopy, Fluorescence; D000074884:Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; D016328:NF-kappa B / Q000276:immunology; D009363:Neoplasm Proteins / Q000276:immunology; D058105:Polymerization; D017452:Receptors, IgG / Q000276:immunology*; D015398:Signal Transduction / Q000276:immunology
chemical_list: D000199:Actins; D048868:Adaptor Proteins, Signal Transducing; D000074018:B-Cell CLL-Lymphoma 10 Protein; C118591:BCL10 protein, human; D053468:CARD Signaling Adaptor Proteins; D016328:NF-kappa B; D009363:Neoplasm Proteins; D017452:Receptors, IgG; D020169:Caspases; C400109:MALT1 protein, human; D000074884:Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
keywords: Actin polymerisation; BCL10; CBM complex; Combined immunodeficiency; FCγR; Primary immunodeficiency