title: Short term results comparison of intraarticular platelet-rich plasma (prp) and hyaluronic acid (ha) applications in early stage of knee osteoarthritis.
abstract: OBJECTIVE
  The aim of this study is to compare the short-term results of intra-articular platelet-rich plasma (PRP) and hyaluronic acid (HA) administrations in early knee osteoarthritis.
  
  
  METHODS
  One hundred and eighteen patients (mean age: 59.3±8.55) who were clinically and radiologically documented with a knee osteoarthritis diagnosis between May and December 2013 were evaluated. For the radiological evaluation, the Kellgren-Lawrence radiological classification scale was employed. The data of stage 1 and 2 patients with osteoarthritis were gathered retrospectively according to the Kellgren-Lawrence classification. The patients were given intra-articular PRP or HA treatments a total of three times, one week apart. 61 patients (102 knees) were involved in the PRP group, and 57 patients (97 knees) were involved in the HA group. The patients were evaluated using the Knee Society's Knee Scoring System (KSS) and the Visual Analog Scale (VAS) scoring system before the treatment and at three and six months after the treatment.
  
  
  RESULTS
  In the PRP and HA groups, when pre-treatment KSS and VAS scores were compared with post-treatment three and six-month scores, a statistically significant difference was seen. When the groups were compared with each other, there was no significant difference between pre-treatment KSS and VAS pain scores; however, a significant difference was found between post-treatment three and six-month scores.
  
  
  CONCLUSIONS
  In this study, the intra-articular PRP administration was more efficient than the HA administration in early knee osteoarthritis.
authors.affiliation: Department of Orthopaedics and Traumatology, Bahcesehir University School of Medicine Istanbul, Turkey.
authors.forename: Volkan
authors.initials: V
authors.lastname: Kilincoglu
authors.affiliation: Department of Fizikomer Physical Therapy Centre Gaziantep, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Yeter
authors.affiliation: Department of Orthopaedics and Traumatology, Medicalpark Hospital Gaziantep, Turkey.
authors.forename: Erkan
authors.initials: E
authors.lastname: Servet
authors.affiliation: Department of Orthopaedics and Traumatology, Medicalpark Hospital Gaziantep, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kangal
authors.affiliation: Department of Medical Oncology Centre, Medicalpark Hospital Gaziantep, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yildirim
keywords: Platelet-rich plasma; hyaluronic acid; intra-articular treatment; knee osteoarthritis