title: Serum oxidized low density lipoprotein levels in preeclamptic and normotensive pregnants.
abstract: BACKGROUNDS/AIM: The aim of the study was to determine serum lipids and oxidized low density lipoprotein (ox-LDL) levels in preeclamptic pregnants and compare with those of normotensives.
  
  
  METHODS
  Ox-LDL levels were determined by enzyme linked immunosorbent assay (ELISA); total cholesterol, hight density lipoprotein (HDL)-cholesterol and triglyceride levels were measured by enzymatic colorimetric assay in 26 normotensive and 27 preeclamptic pregnants. LDL and very low density lipoprotein (VLDL) cholesterol was calculated by Friedwald formula.
  
  
  RESULTS
  Serum levels of Ox-LDL (U/L), total-cholesterol (mg/dL), HDL-cholesterol (mg/dL), LDL-cholesterol (mg/dL), triglyceride (mg/dL), and VLDL-cholesterol (mg/dL) in normotensive and preeclamptic pregnants were found as 130±60 and 133±69; 248±49 and 248±81; 67±14 and 61±16; 147±61 and 135±59; 207±76 and 256±87; 41±15 and 50±17, respectively. Mean values of Ox-LDL and other lipid parameters were higher than the upper limits of their reference ranges in both of groups. However no significant differences were found in Ox-LDL, total, HDL and LDL-cholesterol levels between two groups. However, the levels of triglyceride and VLDL-cholesterol were significantly higher in preeclampsia group.
  
  
  CONCLUSIONS
  The present results suggest that the levels of serum Ox-LDL and other lipid parameters rise as a result of pregnancy rather than as a result of preeclampsia.
authors.forename: A
authors.initials: A
authors.lastname: Kozan
authors.forename: S Turkmen
authors.initials: ST
authors.lastname: Yildirmak
authors.forename: V
authors.initials: V
authors.lastname: Mihmanli
authors.forename: H
authors.initials: H
authors.lastname: Ayabakan
authors.forename: Y G
authors.initials: YG
authors.lastname: Cicek
authors.forename: V
authors.initials: V
authors.lastname: Kalaslioglu
authors.forename: S
authors.initials: S
authors.lastname: Doean
authors.forename: H Cerci
authors.initials: HC
authors.lastname: Cebeci
mesh_terms: D000328:Adult; D001794:Blood Pressure; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy / Q000097:blood*; D014280:Triglycerides / Q000097:blood; D014421:Turkey
chemical_list: D008078:Cholesterol, LDL; D008074:Lipoproteins; D008077:Lipoproteins, LDL; D014280:Triglycerides; C030104:lipoprotein cholesterol; C099252:oxidized low density lipoprotein; D002784:Cholesterol