title: Lost in Translation: Preserving Satellite Cell Function with Global Translational Control.
abstract: Quiescence is highly regulated to preserve stem cell function. In this issue of Cell Stem Cell, Zismanov et al. (2016) show that P-eIF2α, a translational initiation factor, reinforces the quiescent state of muscle stem cells by safeguarding against cell-cycle entry and lineage progression.
authors.affiliation: Department of Orthopaedic Surgery and Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, 35 Medical Center Way, San Francisco, CA 94143, USA.
authors.forename: Susan
authors.initials: S
authors.lastname: Eliazer
authors.affiliation: Department of Orthopaedic Surgery and Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, 35 Medical Center Way, San Francisco, CA 94143, USA. Electronic address: andrew.brack@ucsf.edu.
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Brack
mesh_terms: D002453:Cell Cycle; D002454:Cell Differentiation; D006801:Humans; D032496:Satellite Cells, Skeletal Muscle; D013234:Stem Cells / Q000166:cytology