title: Proposed reference sequences for hepatitis E virus subtypes.
abstract: The nomenclature of hepatitis E virus (HEV) subtypes is inconsistent and makes comparison of different studies problematic. We have provided a table of proposed complete genome reference sequences for each subtype. The criteria for subtype assignment vary between different genotypes and methodologies, and so a conservative pragmatic approach has been favoured. Updates to this table will be posted on the International Committee on Taxonomy of Viruses website (http://talk.ictvonline.org/r.ashx?C). The use of common reference sequences will facilitate communication between researchers and help clarify the epidemiology of this important human pathogen. This subtyping procedure might be adopted for other taxa of the genus Orthohepevirus.
authors.affiliation: University of Edinburgh, Centre for Immunity, Infection and Evolution, Edinburgh, Scotland, UK.
authors.forename: Donald B
authors.initials: DB
authors.lastname: Smith
authors.affiliation: University of Edinburgh, Centre for Immunity, Infection and Evolution, Edinburgh, Scotland, UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Simmonds
authors.affiliation: INSERM, UMR1043, Toulouse F-31300, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Izopet
authors.affiliation: Veterinary Virology and Animal Viral Diseases, Department of Infectious and Parasitic Diseases, Fundamental and Applied Research for Animal Health Centre, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.
authors.forename: Edmilson F
authors.initials: EF
authors.lastname: Oliveira-Filho
authors.affiliation: Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute for Novel and Emerging Infectious Diseases, Greifswald - Insel Riems, Germany.|German Center for Infection Research DZIF, partner site Hamburg-Luebeck-Borstel-Insel Riems, Germany.
authors.forename: Rainer G
authors.initials: RG
authors.lastname: Ulrich
authors.affiliation: Federal Institute for Risk Assessment, Berlin, Germany.
authors.forename: Reimar
authors.initials: R
authors.lastname: Johne
authors.affiliation: Justus-Liebig-Univeristy, Giessen, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Koenig
authors.affiliation: The Wellcome Trust/DBT India Alliance, Hyderabad, India.
authors.forename: Shahid
authors.initials: S
authors.lastname: Jameel
authors.affiliation: University College London, London, UK.
authors.forename: Tim J
authors.initials: TJ
authors.lastname: Harrison
authors.affiliation: College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.
authors.forename: Xiang-Jin
authors.initials: XJ
authors.lastname: Meng
authors.affiliation: Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Tochigi-ken, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Okamoto
authors.affiliation: Central Veterinary Institute, Wageningen University and Research Centre, Lelystad, The Netherlands.
authors.forename: Wim H M
authors.initials: WHM
authors.lastname: Van der Poel
authors.affiliation: Centers for Disease Control and Prevention, National Center for HIV/Hepatitis/STD/TB Prevention, Division of Viral Hepatitis, Atlanta, GA, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Purdy
mesh_terms: D001483:Base Sequence; D005838:Genotype; D016751:Hepatitis E / Q000821:virology*; D016752:Hepatitis E virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA / Q000379:methods*