title: Attapulgite Nanoparticles-Modified Monolithic Column for Hydrophilic In-Tube Solid-Phase Microextraction of Cyromazine and Melamine.
abstract: In current study, a novel monolithic capillary column with embedded attapulgite nanoparticles has been developed and exploited as a stationary phase in hydrophilic in-tube solid phase microextraction (SPME) of cyromazine and melamine. The fibrillar attapulgite nanoparticles were embedded in the poly(1-vinyl-3-(butyl-4-sulfonate) imidazolium-co-acrylamide-co-N,N'-methylenebis(acrylamide)) (poly(VBSIm-AM-MBA)) monolith via in situ polymerization. The attapulgite/polymerization ratio of the monolith was finely optimized. Primary factors of in-tube SPME including sample solvent, elution solvent, sample loading volume, elution volume, sample loading flow rate, and elution flow rate were thoroughly evaluated. Under optimal conditions, the limits of detection (LODs) were found to be 21.1 and 0.3 ng mL(-1) for cyromazine and melamine in the milk formula sample, respectively. Also, the recoveries of cyromazine and melamine spiked in the sample ranged from 94.5% to 109.9% with RSDs less than 7.6%.
authors.affiliation: College of Chemical Engineering, Ningbo University of Technology , Ningbo 315016, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Wang
authors.affiliation: Xiangshan Entry-Exit Inspection and Quarantine , Xiangshan 310014, China.
authors.forename: Yihui
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Biological Chemistry, The Johns Hopkins University School of Medicine , Baltimore, Maryland 21205, United States.
authors.forename: Junfeng
authors.initials: J
authors.lastname: Ma
authors.affiliation: College of Chemical Engineering, Ningbo University of Technology , Ningbo 315016, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Qian
authors.affiliation: College of Chemical Engineering, Ningbo University of Technology , Ningbo 315016, China.
authors.forename: Zhenfeng
authors.initials: Z
authors.lastname: Jin
authors.affiliation: Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023, China.
authors.forename: Lihua
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian 116023, China.
authors.forename: Yukui
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000818:Animals; D057927:Hydrophobic and Hydrophilic Interactions; D008892:Milk / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D052617:Solid Phase Microextraction / Q000295:instrumentation*; D013499:Surface Properties; D014227:Triazines / Q000032:analysis / Q000302:isolation & purification*
chemical_list: D014227:Triazines; C028704:cyromazine; C011907:melamine