title: The TNF-α-308G/A Polymorphism is Not Associated with Ocular Chlamydia trachomatis Infection in Han Chinese Children.
abstract: To investigate the association between the TNF-α-308G/A polymorphism and ocular chlamydia trachomatis (C. Trachomatis) infection among Han Chinese children.
  
  
  
  248 patients and 162 matched healthy controls were recruited. The diagnosis of ocular C. Trachomatis infection was given after clinical observation and latex immunochromatography tests. The TNF-α-308G/A polymorphism was genotyped by sequencing.
  
  
  
  No association was found between the TNF-α-308G/A polymorphism and ocular C. Trachomatis infection.
  
  
  
  The TNF-α-308A polymorphism is unlikely to play a major role in the risk for ocular C. Trachomatis in the Chinese population.
authors.affiliation: a Department of Preventative Ophthalmology , Shanghai Eye Diseases Prevention & Treatment Center , Shanghai , China .|b Department of Ophthalmology , Shanghai First People's Hospital, Shanghai Jiao Tong University , Shanghai , China , and.
authors.forename: Wenwen
authors.initials: W
authors.lastname: Xue
authors.affiliation: c Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University , Shanghai , China.
authors.forename: Qingzhong
authors.initials: Q
authors.lastname: Wang
authors.affiliation: c Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University , Shanghai , China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Li
authors.affiliation: a Department of Preventative Ophthalmology , Shanghai Eye Diseases Prevention & Treatment Center , Shanghai , China .
authors.forename: Lina
authors.initials: L
authors.lastname: Lu
authors.affiliation: a Department of Preventative Ophthalmology , Shanghai Eye Diseases Prevention & Treatment Center , Shanghai , China .
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Zhu
authors.affiliation: a Department of Preventative Ophthalmology , Shanghai Eye Diseases Prevention & Treatment Center , Shanghai , China .
authors.forename: Xiangui
authors.initials: X
authors.lastname: He
authors.affiliation: a Department of Preventative Ophthalmology , Shanghai Eye Diseases Prevention & Treatment Center , Shanghai , China .
authors.forename: Rong
authors.initials: R
authors.lastname: Zhao
authors.affiliation: c Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University , Shanghai , China.
authors.forename: Yongyong
authors.initials: Y
authors.lastname: Shi
authors.affiliation: a Department of Preventative Ophthalmology , Shanghai Eye Diseases Prevention & Treatment Center , Shanghai , China .|b Department of Ophthalmology , Shanghai First People's Hospital, Shanghai Jiao Tong University , Shanghai , China , and.
authors.forename: Haidong
authors.initials: H
authors.lastname: Zou
mesh_terms: D044466:Asian People / Q000235:genetics*; D002648:Child; D002681:China / Q000453:epidemiology; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D015818:Eye Infections, Bacterial / Q000235:genetics* / Q000382:microbiology; D005260:Female; D005787:Gene Frequency; D060005:Genotyping Techniques; D006801:Humans; D008297:Male; D020641:Polymorphism, Single Nucleotide; D014141:Trachoma / Q000235:genetics* / Q000382:microbiology; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics*
chemical_list: D014409:Tumor Necrosis Factor-alpha
keywords: Association; TNF-α-308G/A; chinese population; trachoma