title: A New 3'-Prenyloxypsoralen from the Raw Fruits of Aegle marmelos and its Cytotoxic Activity.
abstract: One new furanocoumarin, 3'-prenyloxypsoralen (1), and two known furanocoumarins, imperatorin (2) and xanthotoxin (3) were isolated from the raw fruits of Aegle marmelos. The structures of the isolated coumarins were confirmed by spectroscopic evidence. Compound 1 exhibited moderate cytotoxic activity against HEK293, HeLa, MCF7, and HT29 cell lines with IC50 values of 31.2, 44.8, 36.3, and > 50.0 µg/mL, respectively.
authors.forename: Widchaya
authors.initials: W
authors.lastname: Radchatawedchakoon
authors.forename: Suthep
authors.initials: S
authors.lastname: Bamrungsuk
authors.forename: Siriporn
authors.initials: S
authors.lastname: Namwijit
authors.forename: Nuttapon
authors.initials: N
authors.lastname: Apiratikul
authors.forename: Uthai
authors.initials: U
authors.lastname: Sakee
authors.forename: Boon-ek
authors.initials: BE
authors.lastname: Yingyongnarongkul
mesh_terms: D045471:Aegle / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D011564:Furocoumarins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D057809:HEK293 Cells; D019073:HT29 Cells; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D011564:Furocoumarins; D010936:Plant Extracts