title: Comparison Between an Empirically Derived and a Standard Classification of Amnestic Mild Cognitive Impairment From a Sample Of Adults With Subjective Cognitive Complaints.
abstract: The aim of this study is to compare an empirically derived classification of amnestic mild cognitive impairment (aMCI) from a sample of adults with subjective cognitive complaints by using cluster analysis of their performance on the California Verbal Learning Test (CVLT) with a classification of aMCI based on standard clinical criteria.
  
  
  
  Three hundred ninety-one individuals aged 48 years and older were diagnosed as aMCI or healthy controls. Cluster analysis of the CVLT performance was conducted, followed by logistic regression analysis.
  
  
  
  A two-cluster solution performed on the CVLT measures correctly classified 98.0% of the aMCI patients and 73.4% of the healthy controls diagnosed by using standard aMCI criteria.
  
  
  
  The empirically derived classification of aMCI is consistent with the classification based on standard criteria; however, standard criteria should also be considered to prevent false positives.
authors.affiliation: University of Santiago de Compostela, Spain maria.campos@usc.es.
authors.forename: María
authors.initials: M
authors.lastname: Campos-Magdaleno
authors.affiliation: University of Santiago de Compostela, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Facal
authors.affiliation: University of Santiago de Compostela, Spain.
authors.forename: Onésimo
authors.initials: O
authors.lastname: Juncos-Rabadán
authors.affiliation: University of Santiago de Compostela, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Picón
authors.affiliation: University of Santiago de Compostela, Spain.
authors.forename: Arturo Xosé
authors.initials: AX
authors.lastname: Pereiro
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition; D003072:Cognition Disorders; D060825:Cognitive Dysfunction / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests
keywords: cognitive impairment; diagnosis; early detection; subjective cognitive complaints; verbal memory