title: Radial versus femoral artery access for percutaneous coronary angiography and intervention: a systematic review and meta-analysis of randomized controlled trials in Chinese population.
abstract: To compare the feasibility, efficiency and safety of coronary angiography (CAG) and interventional procedures between the radial and femoral catheterization approaches in Chinese population using systematic review and meta-analysis, we conducted a search of the studies comparing radial and femoral catheterization approaches in patients underwent either CAG or percutaneous coronary intervention (PCI) in Chinese population. Fixed-effect relative risk (RR) for the primary end points and the second end points were compared between the two approaches. A total of 27 studies (n=8,749 patients) were finally included in the analysis. The success rate of radial approach was slightly lower than that of femoral approach in patients receiving CAG (P=0.004), but similar in patients receiving a further PCI treatment (P=0.11). The risk of major adverse cardiovascular events (MACEs) was similar between two approaches (P=0.27). Radial catheterization had a significantly lower rate of puncture site complications (P<0.00001), but a lower rate of puncture success rate (P=0.02). In patients with acute myocardial infarction (AMI), there was no difference in neither the risk of MACEs nor PCI success rate between two approaches (P=0.23 and 0.45, respectively), but a board line decrease of puncture success rate was observed in radial catheterization group (P=0.04). There were no significant differences in the volumes of contrast media, X-ray exposure time and operation time between the two approaches (all P>0.05). Thus, we concluded that radial approach is a safe method for CAG or PCI compared to traditional femoral approach in Chinese population due to their similar success rate of the procedure and risk of MACEs, and a decreased risk of puncture site complications.
authors.affiliation: Department of Cardiology, Hebi City People's Hospital Jiuzhou Road No. 79, Qibin District, Hebi 458030, Henan Province, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
authors.affiliation: Department of Cardiology, Hebi City People's Hospital Jiuzhou Road No. 79, Qibin District, Hebi 458030, Henan Province, China.
authors.forename: Xue Liang
authors.initials: XL
authors.lastname: Gao
authors.affiliation: Department of Cardiology, Hebi City People's Hospital Jiuzhou Road No. 79, Qibin District, Hebi 458030, Henan Province, China.
authors.forename: Bei Fang
authors.initials: BF
authors.lastname: Li
authors.affiliation: Department of Cardiology, Hebi City People's Hospital Jiuzhou Road No. 79, Qibin District, Hebi 458030, Henan Province, China.
authors.forename: Xue Zhi
authors.initials: XZ
authors.lastname: Ding
authors.affiliation: Department of Cardiology, Hebi City People's Hospital Jiuzhou Road No. 79, Qibin District, Hebi 458030, Henan Province, China.
authors.forename: Zi Hao
authors.initials: ZH
authors.lastname: Wang
authors.affiliation: Department of Cardiology, Hebi City People's Hospital Jiuzhou Road No. 79, Qibin District, Hebi 458030, Henan Province, China.
authors.forename: Yan Ping
authors.initials: YP
authors.lastname: Dang
authors.affiliation: Department of Cardiology, Hebi City People's Hospital Jiuzhou Road No. 79, Qibin District, Hebi 458030, Henan Province, China.
authors.forename: Yang Gui
authors.initials: YG
authors.lastname: Liu
authors.affiliation: Department of Cardiology, Hebi City People's Hospital Jiuzhou Road No. 79, Qibin District, Hebi 458030, Henan Province, China.
authors.forename: Yun Fu
authors.initials: YF
authors.lastname: Li
keywords: Radial artery; acute myocardial infarction (AMI); coronary angiography (CAG); coronary disease; femoral artery; meta-analysis; percutaneous coronary intervention (PCI); systematic review