title: Compatibility of Spatially Coded Apertures with a Miniature Mattauch-Herzog Mass Spectrograph.
abstract: In order to minimize losses in signal intensity often present in mass spectrometry miniaturization efforts, we recently applied the principles of spatially coded apertures to magnetic sector mass spectrometry, thereby achieving increases in signal intensity of greater than 10× with no loss in mass resolution Chen et al. (J. Am. Soc. Mass Spectrom. 26, 1633-1640, 2015), Russell et al. (J. Am. Soc. Mass Spectrom. 26, 248-256, 2015). In this work, we simulate theoretical compatibility and demonstrate preliminary experimental compatibility of the Mattauch-Herzog mass spectrograph geometry with spatial coding. For the simulation-based theoretical assessment, COMSOL Multiphysics finite element solvers were used to simulate electric and magnetic fields, and a custom particle tracing routine was written in C# that allowed for calculations of more than 15 million particle trajectory time steps per second. Preliminary experimental results demonstrating compatibility of spatial coding with the Mattauch-Herzog geometry were obtained using a commercial miniature mass spectrograph from OI Analytical/Xylem.
authors.affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
authors.forename: Zachary E
authors.initials: ZE
authors.lastname: Russell
authors.affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
authors.forename: Shane T
authors.initials: ST
authors.lastname: DiDona
authors.affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
authors.forename: Jason J
authors.initials: JJ
authors.lastname: Amsden
authors.affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
authors.forename: Charles B
authors.initials: CB
authors.lastname: Parker
authors.affiliation: CMS Field Products, OI Analytical, a Xylem brand, College Station, TX, 77842-9010, USA.
authors.forename: Gottfried
authors.initials: G
authors.lastname: Kibelka
authors.affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Gehm
authors.affiliation: Department of Electrical and Computer Engineering, Duke University, Durham, NC, 27708, USA. jeff.glass@duke.edu.
authors.forename: Jeffrey T
authors.initials: JT
authors.lastname: Glass
keywords: Charged particle optics; Coded aperture; Magnetic Sector; Mattauch-Herzog; Miniature mass spectrometer