title: Integrative Advanced Oxidation and Biofiltration for Treating Pharmaceuticals in Wastewater.
abstract: Advanced oxidation of active pharmaceutical ingredients (APIs) in wastewater produces transformation products (TPs) that are often more biodegradable than the parent compounds. Secondary effluent from a wastewater treatment plant was treated using UV-based advanced oxidation (LPUV/H2O2 and MPUV/NO3) followed by biological aerated filtration (BAF), and different APIs and their transformation products were monitored. The advanced oxidation processes degraded the APIs by 55-87% (LPUV/H2O2) and 58-95% (MPUV/NO3), while minor loss of APIs was achieved in the downstream BAF system. Eleven TPs were detected following oxidation of carbamazepine (5) and iopromide (6); three key TPs were biodegraded in the BAF system. The other TPs remained relatively constant in the BAF. The decrease in UV absorbance (UVA254) of the effluent in the BAF system was linearly correlated to the degradation of the APIs (for the MPUV/NO3-BAF), and can be applied to monitor the biotransformation of APIs in biological-based systems.
authors.affiliation: Department of Civil, Environmental, and Architectural Engineering, University of Colorado, UCB 428, Boulder, Colorado 80309, USA.
authors.forename: Yaal
authors.initials: Y
authors.lastname: Lester
authors.forename: Diana S
authors.initials: DS
authors.lastname: Aga
authors.forename: Nancy G
authors.initials: NG
authors.lastname: Love
authors.forename: Randolph R
authors.initials: RR
authors.lastname: Singh
authors.forename: Ian
authors.initials: I
authors.lastname: Morrissey
authors.forename: Karl G
authors.initials: KG
authors.lastname: Linden
mesh_terms: D019149:Bioreactors; D005374:Filtration / Q000379:methods*; D010084:Oxidation-Reduction; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000378:metabolism; D010865:Pilot Projects; D014865:Waste Disposal, Fluid / Q000379:methods*; D062065:Wastewater / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000378:metabolism
chemical_list: D004364:Pharmaceutical Preparations; D062065:Wastewater; D014874:Water Pollutants, Chemical