title: [MID- AND LONG-TERM EFFECTIVENESS OF THIRD-GENERATION CERAMIC-ON-CERAMIC TOTAL HIP ARTHROPLASTY IN YOUNGER PATIENTS].
abstract: OBJECTIVE
  To analyze the mid- and long-term effectiveness of the 3rd-generation ceramic-on-ceramic (CoC) total hip arthroplasty (THA) in the younger patients.
  
  
  METHODS
  A retrospective analysis was made on the clinical data of 68 younger patients (73 hips) who accepted the 3rd-generation CoC THA between March 2001 and May 2009. Of 68 cases, 39 was male and 29 was female with the average age of 38.6 years (range, 18-50 years); there were 15 cases (15 hips) of osteonecrosis of the femoral head, 9 cases (9 hips) congenital dysplasia of the hip, 5 cases (8 hips) of ankylosing spondylitis, 10 cases (10 hips) of osteoarthritis of the hip joint, 12 cases (12 hips) of traumatic hip arthritis, 12 cases (12 hips) of femoral neck fracture, 4 cases (6 hips) of rheumatoid hip arthritis, and 1 case (1 hip) of tumor of the femoral neck. The Harris score and University of California Los Angeles (UCLA) score were used to evaluate the hip joint function and activity level respectively. The visual analogue scale (VAS) was used to assess postoperative thigh pain. Radiological signs of osteolysis, loosening, and alumina ceramic related complications were evaluated continuously. And the Kaplan-Meier survival analysis was used to assess the prosthesis survival.
  
  
  RESULTS
  The average duration of follow-up was 9.7 years (range, 6-14 years). Sandwich ceramic liners fracture was observed in 3 cases (3 hips), and revision was performed; 1 case had "squeaking" hip because of physical activity. At last follow-up, Harris score and UCLA score were significantly improved when compared with preoperative scores (P<0.05). Bony healing was obtained in all patients, without osteolysis, loosening, and thigh pain. The VAS score was 0. The 5-year and 10-year cumulative survival rates for ceramic fracture revision were 98.6% and 95.9%, and the 5-year and 10-year cumulative survival rates for osteolysis and loosening revision both were 100%.
  
  
  CONCLUSIONS
  The 3rd-generation CoC prosthesis offer an excellent option for younger patients in THA and the mid- and long-term effectiveness are satisfactory.
authors.forename: Guoyang
authors.initials: G
authors.lastname: Wan
authors.forename: Junying
authors.initials: J
authors.lastname: Sun
authors.forename: Guochun
authors.initials: G
authors.lastname: Zha
authors.forename: Xijiang
authors.initials: X
authors.lastname: Zhao
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Zhenjun
authors.initials: Z
authors.lastname: You
authors.forename: Kangquan
authors.initials: K
authors.lastname: Zhao
authors.forename: Ning
authors.initials: N
authors.lastname: Xu
mesh_terms: D000537:Aluminum Oxide; D001172:Arthritis, Rheumatoid; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D002516:Ceramics; D005260:Female; D005265:Femoral Neck Fractures; D005270:Femur Head; D005271:Femur Head Necrosis; D005272:Femur Neck; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000601:surgery*; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain; D011184:Postoperative Period; D011475:Prosthesis Failure; D011859:Radiography; D012189:Retrospective Studies; D013167:Spondylitis, Ankylosing; D016896:Treatment Outcome
chemical_list: D000537:Aluminum Oxide