title: [RESEARCH PROGRESS OF TISSUE ENGINEERED SCAFFOLDS AND STROMAL-DERIVED FACTOR 1 COMPOSITE GRAFT].
abstract: OBJECTIVE
  To review the research progress of tissue engineered scaffolds and stromal-derived factor 1 (SDF-1) composite graft.
  
  
  METHODS
  The recent papers about SDF-1 with different kinds of tissue engineered scaffolds were reviewed and analyzed. The primary mechanism of SDF-1 homing function for stem cells was retrospected. The results of different kinds of tissue engineered scaffolds carrying SDF-1 for repairing the injured tissues and organs were reviewed.
  
  
  RESULTS
  It is shown that SDF-1 combined with tissue engineered scaffolds will play a role of multipotent stem cells chemotaxis, however, the exact chemotaxis mechanism has not been fully understood. It still needs more researches of SDF-1 effects in vivo.
  
  
  CONCLUSIONS
  Although some research progress has been made in regeneration in situ of tissue engineered scaffolds combined with SDF-1, it will need to further study on the mechanism of chemotactic functions of SDF-1 and its influence on proliferation and differentiation of cells.
authors.forename: Huanyu
authors.initials: H
authors.lastname: Gao
authors.forename: Yanlin
authors.initials: Y
authors.lastname: Li
authors.forename: Di
authors.initials: D
authors.lastname: Jia
authors.forename: Yang
authors.initials: Y
authors.lastname: Yu
authors.forename: Kun
authors.initials: K
authors.lastname: Wang
mesh_terms: D002454:Cell Differentiation; D054377:Chemokine CXCL12 / Q000378:metabolism*; D002633:Chemotaxis; D006801:Humans; D012038:Regeneration; D013234:Stem Cells; D023822:Tissue Engineering / Q000379:methods* / Q000639:trends*; D054457:Tissue Scaffolds; D014945:Wound Healing
chemical_list: D054377:Chemokine CXCL12