title: Bethesda 2014: improving on a paradigm shift.
abstract: The third iteration of the Bethesda System terminology manual was recently published. This update included changes in the reporting of benign endometrial cells, and guidance for special adequacy situations and for cases in which low grade squamous intraepithelial lesions are accompanied by some cells suggesting that a high grade lesion might also be present. In addition, the manual was increased in size to include more illustrations with special studies and comparisons to histology, a greatly increased reference list, and a new chapter devoted to the modern practice of risk-based management. The third edition of the Bethesda manual is meant to serve as a primary reference for the practice of gynecologic cytology designed to provide a uniform system of reporting Worldwide for clinical, teaching, and research purposes.
authors.affiliation: Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
authors.forename: D C
authors.initials: DC
authors.lastname: Wilbur
authors.affiliation: Department of Pathology, Feinberg School of Medicine, Northwestern University and Northwestern Medicine, Chicago, IL, USA.
authors.forename: R
authors.initials: R
authors.lastname: Nayar
mesh_terms: D002584:Cervix Uteri / Q000473:pathology*; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008370:Manuals as Topic; D065006:Papanicolaou Test; D017410:Practice Guidelines as Topic; D065310:Squamous Intraepithelial Lesions of the Cervix / Q000145:classification* / Q000473:pathology; D009626:Terminology as Topic; D002583:Uterine Cervical Neoplasms / Q000145:classification* / Q000473:pathology; D014626:Vaginal Smears
keywords: Bethesda System; Pap test; gynecologic cytology