title: A case of cutaneous Paecilomyces formosus infection in an extremely premature infant.
abstract: BACKGROUND
  Many types of weak pathogenic microorganisms often cause opportunistic infections in extremely preterm infants. Paecilomyces formosus is one such opportunistic fungus that can lead to a serious infection. Here, we report the clinical course of P. formosus infection in an extremely preterm infant.
  
  
  METHODS
  An extremely preterm male infant was born at 23 weeks of gestation. Six days after birth, he developed yellowish-brown nodules on the skin of the back extending to the buttocks. P. formosus was identified by culture of samples from the cutaneous lesions. We treated the infection with intravenous micafungin and lanoconazole ointment application. The skin lesions improved dramatically and healed without scar tissue formation.
  
  
  CONCLUSIONS
  Neonatologists should consider opportunistic P. formosus infections. This is the first report to describe that micafungin is effective for P. formosus cutaneous infection in extremely premature infants.
authors.affiliation: Department of Neonatology, Shikoku Medical Center for Children and Adults, Japan. Electronic address: kuboi-t@shikoku-med.jp.
authors.forename: Toru
authors.initials: T
authors.lastname: Kuboi
authors.affiliation: Division of Neonatology, Tokyo Metropolitan Children's Medical Center, Japan.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Okazaki
authors.affiliation: Department of Neonatology, Shikoku Medical Center for Children and Adults, Japan.
authors.forename: Motohiro
authors.initials: M
authors.lastname: Inotani
authors.affiliation: Department of Neonatology, Shikoku Medical Center for Children and Adults, Japan.
authors.forename: Masashiro
authors.initials: M
authors.lastname: Sugino
authors.affiliation: Department of Neonatology, Shikoku Medical Center for Children and Adults, Japan.
authors.forename: Takaaki
authors.initials: T
authors.lastname: Sadamura
authors.affiliation: Department of Neonatology, Shikoku Medical Center for Children and Adults, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Nakano
authors.affiliation: Department of Neonatology, Shikoku Medical Center for Children and Adults, Japan.
authors.forename: Shoko
authors.initials: S
authors.lastname: Kobayashi
authors.affiliation: Department of Neonatology, Shikoku Medical Center for Children and Adults, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Ota
authors.affiliation: Clinical Laboratory Sciences, Shikoku Medical Center for Children and Adults, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Nishimura
authors.affiliation: Medical Mycology Research Center, Chiba University, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Yaguchi
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001415:Back / Q000473:pathology; D006801:Humans; D062071:Infant, Extremely Premature; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases; D008297:Male; D009181:Mycoses; D009894:Opportunistic Infections; D010143:Paecilomyces; D012867:Skin / Q000473:pathology; D014427:Twins
chemical_list: D000935:Antifungal Agents
keywords: Antifungal agent; Opportunistic infection; Preterm infant