title: Detection of Coxiella burnetii in acute undifferentiated febrile illnesses (AUFIs) in Iran.
abstract: There are limited data on the aetiology of acute undifferentiated febrile illnesses (AUFIs) in Iran. Moreover, Coxiella burnetii has not previously been detected in clinical samples in this country. Previous studies have highlighted the importance of considering C. burnetii as a cause of AUFI. In this retrospective study, in 92 cases of AUFI where Q fever was suspected, C. burnetii DNA was detected in seven samples (7.36%). This is the first molecular confirmation of C. burnetii from clinical samples from Iran.
authors.affiliation: Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran mdkhalili1@yahoo.com mdkhalily@uk.ac.ir.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Khalili
authors.affiliation: Department of Infectious Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Naderi
authors.affiliation: Department of Infectious Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Nasim
authors.initials: N
authors.lastname: Salehnia
authors.affiliation: Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran.
authors.forename: Zeinab
authors.initials: Z
authors.lastname: Abiri
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D001769:Blood / Q000382:microbiology*; D016997:Coxiella burnetii / Q000235:genetics / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000097:blood*; D005260:Female; D006801:Humans; D007492:Iran / Q000453:epidemiology; D016133:Polymerase Chain Reaction / Q000379:methods*; D012150:Polymorphism, Restriction Fragment Length; D011778:Q Fever / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D012189:Retrospective Studies; D012424:Rural Population
chemical_list: D000907:Antibodies, Bacterial; D004269:DNA, Bacterial
keywords: C. burnetii; Iran; febrile; nested PCR