title: Gonococcal Conjunctivitis Despite Successful Treatment of Male Urethritis Syndrome.
abstract: We report a case of progressive, cephalosporin-susceptible, Neisseria gonorrhoeae conjunctivitis despite successful treatment of male urethritis syndrome. We hypothesize that conjunctival infection progressed due to insufficient penetration of cefixime and azithromycin and point out that extragenital infection and male urethritis may not be cured simultaneously in settings where the syndromic approach is used.
authors.affiliation: From the *Anova Health Institute, Johannesburg, South Africa; †Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa; ‡Laboratory of Immunogenetics, Department of Medical Microbiology & Infection Control, VU University Medical Center, Amsterdam, the Netherlands; §School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa; ¶Rotterdam Ophthalmic Institute, Rotterdam, the Netherlands; and ∥Department of Viroscience, Erasmus MC, Rotterdam, the Netherlands.
authors.forename: Remco P H
authors.initials: RP
authors.lastname: Peters
authors.forename: Stephan P
authors.initials: SP
authors.lastname: Verweij
authors.forename: James A
authors.initials: JA
authors.lastname: McIntyre
authors.forename: Erik
authors.initials: E
authors.lastname: Schaftenaar
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use; D020682:Cefixime / Q000627:therapeutic use; D003231:Conjunctivitis / Q000188:drug therapy*; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000302:isolation & purification*; D014526:Urethritis / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin; D020682:Cefixime