title: Detection and Prevalence of Penicillin-Susceptible Staphylococcus aureus in the United States in 2013.
abstract: Using blaZ PCR as the "gold standard," the sensitivities of CLSI penicillin zone edge and nitrocefin-based tests for β-lactamase production in Staphylococcus aureus were 64.5% and 35.5%, respectively, with specificity of 99.8% for both methods. In 2013, 13.5% of 3,083 S. aureus isolates from 31 U.S. centers were penicillin susceptible.
authors.affiliation: Cleveland Clinic, Cleveland, Ohio, USA richtes@ccf.org.
authors.forename: S S
authors.initials: SS
authors.lastname: Richter
authors.affiliation: University of Iowa College of Medicine, Iowa City, Iowa, USA.
authors.forename: G V
authors.initials: GV
authors.lastname: Doern
authors.affiliation: University of Iowa College of Medicine, Iowa City, Iowa, USA.
authors.forename: K P
authors.initials: KP
authors.lastname: Heilmann
authors.affiliation: University of Iowa College of Medicine, Iowa City, Iowa, USA.
authors.forename: S
authors.initials: S
authors.lastname: Miner
authors.affiliation: University of Iowa College of Medicine, Iowa City, Iowa, USA.
authors.forename: S
authors.initials: S
authors.lastname: Tendolkar
authors.affiliation: University of Iowa College of Medicine, Iowa City, Iowa, USA.
authors.forename: F
authors.initials: F
authors.lastname: Riahi
authors.affiliation: University of Iowa College of Medicine, Iowa City, Iowa, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Diekema
mesh_terms: D005798:Genes, Bacterial; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014481:United States / Q000453:epidemiology
chemical_list: D010406:Penicillins