title: Two new menthane monoterpenes from Illicium wardii.
abstract: Two new menthane monoterpenes, wardicines A (1) and B (2), were isolated from the fruits of Illicium wardii A.C. Smith. Their structures were determined on the basis of spectroscopic data analysis. Cytotoxicities of compounds 1 and 2 against three human tumor cell lines A549, HCT-116, and CCRF-CEM were also evaluated, but no significant activities were observed for the two compounds.
authors.affiliation: a Research Center of Natural Resources of Chinese Medicinal Materials and Ethenic Medicine, Jiangxi University of Traditional Chinese Medicine , Nanchang 200433 , China.
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Gao
authors.affiliation: c Logistics Management Office, Science and Technology College of Jiangxi University of Traditional Chinese Medicine , Nanchang 330004 , China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wu
authors.affiliation: b School of Pharmacy, Department of Phytochemistry , Second Military Medical University , Shanghai 200433 , China.
authors.forename: Yun-Heng
authors.initials: YH
authors.lastname: Shen
authors.affiliation: a Research Center of Natural Resources of Chinese Medicinal Materials and Ethenic Medicine, Jiangxi University of Traditional Chinese Medicine , Nanchang 200433 , China.|b School of Pharmacy, Department of Phytochemistry , Second Military Medical University , Shanghai 200433 , China.
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Zhang
mesh_terms: D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D045325:HCT116 Cells; D006801:Humans; D029523:Illicium / Q000737:chemistry; D008610:Menthol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D004365:Drugs, Chinese Herbal; D039821:Monoterpenes; C000613495:wardicine A; C000613496:wardicine B; D008610:Menthol
keywords: Illiciaceae; Illicium wardii; cytotoxicity; monoterpene