title: Severe liver injury due to a homemade flower pollen preparation in a patient with high CYP3A enzyme activity: a case report.
authors.affiliation: Division of Clinical Pharmacology and Toxicology, Geneva University Hospitals, CH-1211, Geneva, Switzerland. victoria.rollason@hcuge.ch.
authors.forename: Victoria
authors.identifier: http://orcid.org/0000-0002-8073-6610
authors.initials: V
authors.lastname: Rollason
authors.affiliation: Division of Gastroenterology and Hepatology, Geneva University Hospitals, CH-1211, Geneva, Switzerland.
authors.forename: Laurent
authors.initials: L
authors.lastname: Spahr
authors.affiliation: Division of Clinical Pharmacology and Toxicology, Geneva University Hospitals, CH-1211, Geneva, Switzerland.
authors.forename: Monica
authors.initials: M
authors.lastname: Escher
mesh_terms: D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000378:metabolism*; D051544:Cytochrome P-450 CYP3A / Q000378:metabolism*; D005260:Female; D035264:Flowers / Q000009:adverse effects*; D006801:Humans; D008099:Liver / Q000201:enzymology; D028321:Plant Preparations / Q000009:adverse effects*; D011058:Pollen / Q000009:adverse effects*
chemical_list: D028321:Plant Preparations; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A
keywords: Adverse drug reaction; CYP3A; Hepatotoxicity; Herbal drug; Phenotyping; Pyrrolizidine alkaloid