title: Letter: Comparison of pyridine and pyrazine derivatives distributions in exhaled breath and exhaled breath condensate after smoking.
abstract: Molecular mass distributions of series of compounds found in exhaled breath after smoking are compared between the direct-breath analysis by extractive electrospray ionization and the analysis of exhaled breath condensate by direct-infusion electrospray ionization mass spectrometry. Although all the analyzed series of compounds are detected by both methods, their relative abundances are different. A number-average mass is used as a quantitative characteristic of the series. It is shown that this value is close for the distributions of the series of compounds in the mass spectrum of exhaled breath condensate and the mass spectrum obtained by summation of direct mass spectra over the breathing time.
authors.affiliation: Department of System Biology in Reproduction, Federal State Budget Institution "Research Center for Obstetrics, Gynecology and Perinatology", 4 Oparin street, Moscow 117997, Russia. vvchagovets@gmail.com.
authors.forename: Vitaliy
authors.initials: V
authors.lastname: Chagovets
authors.affiliation: Department of System Biology in Reproduction, Federal State Budget Institution "Research Center for Obstetrics, Gynecology and Perinatology", 4 Oparin street, Moscow 117997, Russia. Moscow Institute of Physics and Technology, Moscow 141700, Russia. Moscow Institute of Physics and Technology, Moscow 141700, Russia.. konoleha@yandex.ru.
authors.forename: Aleksey
authors.initials: A
authors.lastname: Kononikhin
authors.affiliation: Department of System Biology in Reproduction, Federal State Budget Institution "Research Center for Obstetrics, Gynecology and Perinatology", 4 Oparin street, Moscow 117997, Russia.
authors.forename: Nataliia
authors.initials: N
authors.lastname: Starodubtseva
authors.affiliation: Key Laboratory for Mass Spectrometry and Instrumentation, East China Institute of Technology, 418 Guanglan road, Nanchang, Jiangxi 330013, China.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Ding
authors.affiliation: Key Laboratory for Mass Spectrometry and Instrumentation, East China Institute of Technology, 418 Guanglan road, Nanchang, Jiangxi 330013, China.
authors.forename: Huanwen
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of System Biology in Reproduction, Federal State Budget Institution "Research Center for Obstetrics, Gynecology and Perinatology", 4 Oparin street, Moscow 117997, Russia. vfrankevich@gmail.com.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Frankevich
mesh_terms: D001944:Breath Tests / Q000379:methods*; D045853:Exhalation / Q000502:physiology*; D006801:Humans; D011719:Pyrazines / Q000032:analysis*; D011725:Pyridines / Q000032:analysis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012907:Smoking / Q000378:metabolism*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
chemical_list: D011719:Pyrazines; D011725:Pyridines