title: Angiosarcoma of the gallbladder with hemobilia: a case report.
abstract: A 61-year-old woman presented to our hospital with epigastric pain. She underwent abdominal contrast-enhanced computed tomography, which showed signal enhancement in the gallbladder fundus. As biliary obstruction was suspected, endoscopic nasobiliary drainage was performed, which revealed hemobilia. Based on this finding, gallbladder tumor was suspected, and open cholecystectomy was performed. Immunohistological staining of the resected tissue was positive for factor VIII that led to the diagnosis of gallbladder angiosarcoma. Hepatectomy and biliary reconstruction were performed for disease control; however, the patient died due to multiple liver metastases 4 months after the surgery.
authors.affiliation: Department of Surgery, Yokohama Rosai Hospital.
authors.forename: Koichi
authors.initials: K
authors.lastname: Shinoto
authors.forename: Hajime
authors.initials: H
authors.lastname: Nagase
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kakuta
authors.forename: Masahiko
authors.initials: M
authors.lastname: Ozaki
mesh_terms: D002763:Cholecystectomy; D017809:Fatal Outcome; D005260:Female; D005706:Gallbladder Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D006394:Hemangiosarcoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D006431:Hemobilia / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary*; D008875:Middle Aged