title: Expression of eosinophils be beneficial to early clinical diagnosis of brucellosis.
abstract: OBJECTIVE
  Investigate the expression and significance of eosinophils in brucellosis.
  
  
  METHODS
  Retrospective analysis of clinical data for 151 brucellosis patients (BR group), complete blood count and blood bacterial culture etc.; in addition, 150 general bacterial infection patients (BI group) and 135 persons in healthy physical condition upon testing (NC group) are selected respectively as the control groups to comparatively study expression of white blood cells and eosinophils for brucellosis patients. Adopt t test to compare measurement data.
  
  
  RESULTS
  In comparison with BI group, WBC, NE, EO, MO, NE% and EO% in BR group are reduced but LY, LY% and MO% are increased and such difference shows statistical significance (P<0.01). In comparison with NC group, difference of WBC and NE in BR group shows no statistical significance (P>0.05). NE%, EO and EO% are reduced but MO, LY% and MO% are increased and such difference shows statistical significance (P<0.01). LY is increased and the difference shows statistical significance (P<0.05). White blood cell count is normal or is reduced among most of Brucellosis patients, accounting for 90.73% (137/151); the patients whose eosinophils are reduced account for 75.50% (114/151) and those whose eosinophils disappear are about 18.54% (28/151).
  
  
  CONCLUSIONS
  There is an incidence rate of eosinophils decrease or disappearance in Brucellosis and it shows the indication significance in the diagnosis of early disease.
authors.affiliation: Department of Respiration and Intensive, The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052, Henan Province, China.
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Jiao
authors.affiliation: Department of Respiration and Intensive, The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052, Henan Province, China.
authors.forename: Wei-Li
authors.initials: WL
authors.lastname: Chu
authors.affiliation: Department of Respiration and Intensive, The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052, Henan Province, China.
authors.forename: Gao-Fei
authors.initials: GF
authors.lastname: Ren
authors.affiliation: Department of Respiration and Intensive, The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052, Henan Province, China.
authors.forename: Jun-Na
authors.initials: JN
authors.lastname: Hou
authors.affiliation: Department of Respiration and Intensive, The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052, Henan Province, China.
authors.forename: Ya-Meng
authors.initials: YM
authors.lastname: Li
authors.affiliation: Department of Respiration and Intensive, The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052, Henan Province, China.
authors.forename: Li-Hua
authors.initials: LH
authors.lastname: Xing
keywords: Brucellosis; eosinophils; retrospective study