title: Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles.
abstract: Simultaneous tracking of nanoparticles and encapsulated payload is of great importance and visualizing their activity is arduous. Here we use vibrational spectroscopy to study the in vitro tracking of co-localized lipid nanoparticles and encapsulated drug employing a model system derived from doxorubicin-encapsulated deuterated phospholipid (dodecyl phosphocholine-d38) single tailed phospholipid vesicles.
authors.affiliation: Departments of Bioengineering and Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Carle Foundation Hospital, 502 N. Busey St., Urbana, IL 61801, USA. dipanjan@illinois.edu.
authors.forename: S K
authors.initials: SK
authors.lastname: Misra
authors.affiliation: Department of Bioengineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering, Chemistry, and Mechanical Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 1304 W. Springfield Ave, Urbana, IL 61801, USA. rxb@illinois.edu.
authors.forename: P
authors.initials: P
authors.lastname: Mukherjee
authors.affiliation: Departments of Bioengineering and Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Carle Foundation Hospital, 502 N. Busey St., Urbana, IL 61801, USA. dipanjan@illinois.edu.
authors.forename: A
authors.initials: A
authors.lastname: Ohoka
authors.affiliation: Departments of Bioengineering and Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Carle Foundation Hospital, 502 N. Busey St., Urbana, IL 61801, USA. dipanjan@illinois.edu.
authors.forename: A S
authors.initials: AS
authors.lastname: Schwartz-Duval
authors.affiliation: Department of Bioengineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering, Chemistry, and Mechanical Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 1304 W. Springfield Ave, Urbana, IL 61801, USA. rxb@illinois.edu.
authors.forename: S
authors.initials: S
authors.lastname: Tiwari
authors.affiliation: Department of Bioengineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering, Chemistry, and Mechanical Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 1304 W. Springfield Ave, Urbana, IL 61801, USA. rxb@illinois.edu.
authors.forename: R
authors.initials: R
authors.lastname: Bhargava
authors.affiliation: Departments of Bioengineering and Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Carle Foundation Hospital, 502 N. Busey St., Urbana, IL 61801, USA. dipanjan@illinois.edu.
authors.forename: D
authors.initials: D
authors.lastname: Pan
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D003903:Deuterium / Q000737:chemistry; D004317:Doxorubicin / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D061986:MCF-7 Cells; D018625:Microscopy, Atomic Force; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry*; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000737:chemistry; D013059:Spectrum Analysis, Raman; D014961:X-Ray Diffraction
chemical_list: D000903:Antibiotics, Antineoplastic; D010767:Phosphorylcholine; C028810:dodecylphosphocholine; D004317:Doxorubicin; D003903:Deuterium