title: Electrophoretic deposition of graphene oxide reinforced chitosan-hydroxyapatite nanocomposite coatings on Ti substrate.
abstract: Electrophoretic deposition (EPD) is a facile and feasible technique to prepare functional nanocomposite coatings for application in orthopedic-related implants. In this work, a ternary graphene oxide-chitosan-hydroxyapatite (GO-CS-HA) composite coating on Ti substrate was successfully fabricated by EPD. Coating microstructure and morphologies were investigated by scanning electron microscopy, contact angle test, Raman spectroscopy, Fourier transform infrared spectroscopy and thermogravimetric analysis. It was found GO-CS surface were uniformly decorated by HA nanoparticles. The potentiodynamic polarization test in simulated body fluid indicated that the GO-CS-HA coatings could provide effective protection of Ti substrate from corrosion. This ternary composite coating also exhibited good biocompatibility during incubation with MG63 cells. In addition, the nanocomposite coatings could decrease the attachment of Staphylococcus aureus.
authors.affiliation: Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, No. 5 Yi-He-Yuan Road, Hai-Dian District, Beijing, 100871, People's Republic of China. shiyuying1204@163.com.
authors.forename: Y Y
authors.initials: YY
authors.lastname: Shi
authors.affiliation: Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, No. 5 Yi-He-Yuan Road, Hai-Dian District, Beijing, 100871, People's Republic of China. limingecust@pku.edu.cn.
authors.forename: M
authors.initials: M
authors.lastname: Li
authors.affiliation: Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, No. 5 Yi-He-Yuan Road, Hai-Dian District, Beijing, 100871, People's Republic of China. csu.liuqian@gmail.com.
authors.forename: Q
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, No. 5 Yi-He-Yuan Road, Hai-Dian District, Beijing, 100871, People's Republic of China. dzjzj@foxmail.com.
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Jia
authors.affiliation: Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, No. 5 Yi-He-Yuan Road, Hai-Dian District, Beijing, 100871, People's Republic of China. 1046731041@qq.com.
authors.forename: X C
authors.initials: XC
authors.lastname: Xu
authors.affiliation: Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, No. 5 Yi-He-Yuan Road, Hai-Dian District, Beijing, 100871, People's Republic of China. chengyan@pku.edu.cn.
authors.forename: Y
authors.initials: Y
authors.lastname: Cheng
authors.affiliation: Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Interdisciplinary Studies, Peking University, No. 5 Yi-He-Yuan Road, Hai-Dian District, Beijing, 100871, People's Republic of China. yfzheng@pku.edu.cn.|Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing, 100871, People's Republic of China. yfzheng@pku.edu.cn.
authors.forename: Y F
authors.initials: YF
authors.lastname: Zheng
mesh_terms: D048271:Chitosan / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D004586:Electrophoresis / Q000379:methods*; D006108:Graphite / Q000737:chemistry*; D008422:Materials Testing; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites / Q000737:chemistry*; D014025:Titanium / Q000737:chemistry*
chemical_list: D006108:Graphite; D048271:Chitosan; D017886:Durapatite; D014025:Titanium