title: The Most Common Type of HPV in Women with Atypical Squamous Cell of Undetermined Significance (ASCUS) in Pap Smear in Iran-Yazd.
abstract: BACKGROUND
  Cervical cancer is the third most gynecological cancer and one of the common causes of cancer death in women in Iran and the other developing countries. Human Papilloma Virus (HPV) is a known Risk factor in cervical cancer, but according to HPV deference types, the high risk and low risks differ.
  
  
  METHODS
  We evaluate the most common high risk and low risk HPV type in 180 females with an atypical squamous cells of undetermined significance (ASCUS) results in pap smear in Gynecological Oncology Clinic in Shahid Sadoughi Hospital in Yazd, Iran within 2012 to 2014.HPV typing was done with polymerase chain reaction (PCR) method. The data obtained were recorded in a questionnaire and analyzed by SPSS software.
  
  
  RESULTS
  More common low risk HPV type in ASCUS patients was type 6 (63.6%) and then type 11 (36.4%). Type 16 was the most common high risk HPV type.
  
  
  CONCLUSIONS
  HPV DNA typing for better management of women With ASCUS is important and this study showed HPV type 16 is the most prevalent type in ASCUS patients. It seems the living region is important in HPV type distribution and Quadri-valant Vaccine can prevent cervical cancer in Iran because the most common low risk HPV is type6 and 11, and HPV 16 is the most common high risk HPV.
authors.affiliation: Associate prof, Gynecological Oncology fellowship, Clinical research development, Shahid Sadoughi University of Medical Science, Yazd, Iran;
authors.forename: Mojgan
authors.initials: M
authors.lastname: Karimi-Zarchi
authors.affiliation: Associate prof, Obstetrics & Gynecologist, Shahid Sadoughi University of Medical Science, Yazd, Iran;
authors.forename: Afsarosadat
authors.initials: A
authors.lastname: Tabatabaie
authors.affiliation: Obstetrics & Gynecologist, Shahid Sadoughi University of Medical Science, Yazd, Iran;
authors.forename: Alie
authors.initials: A
authors.lastname: Dehghani-Firoozabadi
authors.affiliation: Epidemiologist, Shahid Sadoughi University of Medical Science, Yazd, Iran;
authors.forename: Farima
authors.initials: F
authors.lastname: Shamsi
authors.affiliation: General physician, Shahid Sadoughi University of Medical Science, Yazd, Iran;
authors.forename: Maleknaz
authors.initials: M
authors.lastname: Baghianimoghaddam
authors.affiliation: Pathologist, Azad University of Medical Science, Yazd, Iran;
authors.forename: Mandana
authors.initials: M
authors.lastname: Dargahi
authors.affiliation: Medical Student, Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran;
authors.forename: Pouria
authors.initials: P
authors.lastname: Yazian
authors.affiliation: School of Nursing and Midwifery, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Shahnaz
authors.initials: S
authors.lastname: Mojahed
keywords: HPV; atypical squamous cells of undetermined significance; cervical cancer; high risk; low risk; management; prevention