title: Vestibular evoked myogenic potentials in patients with ankylosing spondylitis.
abstract: Ankylosing spondylitis (AS) is a chronic systemic inflammatory disease with unknown etiology. Although sacroiliac joint involvement is the classic sign along with the formed immune mediators, it may result in immune-mediated inner ear disease and may cause damage to the audiovestibular system. Vestibular evoked myogenic potentials (VEMP) is a clinical reflex test used in the diagnosis of vestibular diseases and is performed by recording and evaluating the muscle potentials resulting from the stimulation of the vestibular system with different stimuli. The aim of this study is to evaluate the cervical VEMP test results in AS patients without vestibular symptoms. Thirty-three patients with AS and a control group of 30 healthy volunteers with similar demographic characteristics were evaluated in the study. VEMP wave latency, P13-N23 wave amplitude, and VEMP asymmetry ratio (VAR) values were compared between the groups. The relationship between clinical and laboratory findings of the AS patients and VEMP data were also investigated. Compared with healthy people, this study shows the response rate of patients with ankylosing spondylitis was reduced in the VEMP test, and P13-N23 wave amplitude showed a decrease in AS patients who had VEMP response (p < 0.001). There was no correlation between the clinical and laboratory findings and VEMP findings in patients with ankylosing spondylitis. The data obtained from this study suggest that AS may lead to decreased sensitivity of the vestibular system.
authors.affiliation: Department of Otorhinolaryngology, Recep Tayyip Erdogan University, Islampasa Mahallesi, Sehitler Caddesi, No: 74, PB: 53020, Rize, Turkey. akozgur53@gmail.com.
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: Özgür
authors.affiliation: Department of Physical Medicine and Rehabilitation, Recep Tayyip Erdogan University, Rize, Turkey.
authors.forename: Münevver
authors.initials: M
authors.lastname: Serdaroğlu Beyazal
authors.affiliation: Department of Otorhinolaryngology, Recep Tayyip Erdogan University, Islampasa Mahallesi, Sehitler Caddesi, No: 74, PB: 53020, Rize, Turkey.
authors.forename: Suat
authors.initials: S
authors.lastname: Terzi
authors.affiliation: Department of Otorhinolaryngology, Recep Tayyip Erdogan University, Islampasa Mahallesi, Sehitler Caddesi, No: 74, PB: 53020, Rize, Turkey.
authors.forename: Zerrin Özergin
authors.initials: ZÖ
authors.lastname: Coşkun
authors.affiliation: Department of Otorhinolaryngology, Recep Tayyip Erdogan University, Islampasa Mahallesi, Sehitler Caddesi, No: 74, PB: 53020, Rize, Turkey.
authors.forename: Engin
authors.initials: E
authors.lastname: Dursun
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007759:Labyrinth Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013167:Spondylitis, Ankylosing / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D058585:Vestibular Evoked Myogenic Potentials / Q000502:physiology*; D014722:Vestibule, Labyrinth / Q000503:physiopathology*; D055815:Young Adult
keywords: Ankylosing spondylitis; Immune-mediated inner ear disease; VEMP; Vestibular system