title: The Effect of Caffeic Acid Phenethyl Ester (CAPE) Fortification on the Liver Element Distribution that Occurs After Exercise.
abstract: The purpose of this study is to examine the effect of the caffeic acid phenethyl ester (CAPE) fortification applied to the rats, which were made to exercise, on the liver elements. The study was conducted on 32 Sprague-Dawley male rats. The experimental animals were divided into 4 groups in equal numbers. Group 1 is the group which was applied 10 μmol/kg/day CAPE as intraperitoneal (IP) for 4 weeks, and they were not made to exercise at the end of the application. Group 2 is the group which was applied 10 μmol/kg/day CAPE as IP for 4 weeks, and they were made to exercise at the end of the 4th week. Group 3 is the general control group. Group 4 is the swimming control group. A 10 mmol/kg CAPE application dissolved in ethyl alcohol of 10 % was applied to the CAPE group. Sodium (Na), zinc (Zn), calcium (Ca), iron (Fe), chrome (Cr), magnesium (Mg), potassium (K), copper (Cu) and cadmium (Cd) levels were identified in the liver samples at the end of the application. The results of the study suggest that exercise and CAPE fortification in rats cause changes in the Na, Zn, Ca, Fe and Cr parameters in liver tissues, and it does not affect Cd, Cu, Mg and K element distribution. It is thought that CAPE fortification would be helpful for preserving those parameters whose levels are known to be changing with exercise.
authors.affiliation: Faculty of Sports Science, Usak University, Usak, Turkey. mus_akil@yahoo.com.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Akil
authors.affiliation: Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Usak University, 64000, Usak, Turkey.
authors.forename: Funda Karabag
authors.initials: FK
authors.lastname: Coban
authors.affiliation: Faculty of Arts and Sciences, Department of Chemistry, Gazi University, Ankara, Turkey.
authors.forename: Ozcan
authors.initials: O
authors.lastname: Yalcinkaya
mesh_terms: D000818:Animals; D002104:Cadmium / Q000032:analysis; D002109:Caffeic Acids / Q000008:administration & dosage / Q000494:pharmacology*; D002118:Calcium / Q000032:analysis; D002857:Chromium / Q000032:analysis; D003300:Copper / Q000032:analysis; D007274:Injections, Intraperitoneal; D007501:Iron / Q000032:analysis; D008099:Liver / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D008274:Magnesium / Q000032:analysis; D008297:Male; D010626:Phenylethyl Alcohol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D010805:Physical Conditioning, Animal; D011188:Potassium / Q000032:analysis; D051381:Rats; D017207:Rats, Sprague-Dawley; D012964:Sodium / Q000032:analysis; D014018:Tissue Distribution; D015032:Zinc / Q000032:analysis
chemical_list: D002109:Caffeic Acids; D002104:Cadmium; D002857:Chromium; D003300:Copper; D012964:Sodium; D007501:Iron; C055494:caffeic acid phenethyl ester; D008274:Magnesium; D015032:Zinc; D010626:Phenylethyl Alcohol; D011188:Potassium; D002118:Calcium
keywords: CAPE; Element; Exercise; Liver