title: Early and Late Infections in Newborns: Where Do We Stand? A Review.
abstract: Neonatal sepsis still represents an important cause of mortality and morbidity among infants. According to the onset, we can distinguish "early onset sepsis" when microbiological cultures positive for external pathogens come from newborns during the first 7 days of life (maternal intrapartum transmission); "late onset sepsis" when microbiological cultures positive for external pathogens come from newborns after the first 7 days from delivery (postnatal acquisition). In this review we synthesize the incidence, risk factors, clinical manifestations, and methods of diagnosis and treatment of each type of neonatal infection, in order to better define such a pathological condition which is of great importance in common clinical practice.
authors.affiliation: Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO) University of Bari, Bari, Italy. Electronic address: francescacortese@hotmail.it.
authors.forename: Francesca
authors.initials: F
authors.lastname: Cortese
authors.affiliation: Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO) University of Bari, Bari, Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Scicchitano
authors.affiliation: Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO) University of Bari, Bari, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Gesualdo
authors.affiliation: Neonatology and NICU Section, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari, Bari, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Filaninno
authors.affiliation: Neonatology and NICU Section, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari, Bari, Italy.
authors.forename: Elsa
authors.initials: E
authors.lastname: De Giorgi
authors.affiliation: Neonatology and NICU Section, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari, Bari, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Schettini
authors.affiliation: Neonatology and NICU Section, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari, Bari, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Laforgia
authors.affiliation: Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO) University of Bari, Bari, Italy.
authors.forename: Marco Matteo
authors.initials: MM
authors.lastname: Ciccone
mesh_terms: D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D000071074:Neonatal Sepsis / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D012307:Risk Factors
keywords: early onset sepsis; late onset sepsis; newborns