title: Adenoid hypertrophy and chronic rhinosinusitis: Helicobacter pylori on antral lavages, adenoid tissue and salival inmunoglobuline A on paediatric patients.
abstract: OBJECTIVE
  To determine Helicobacter pylori presence on antral lavages, adenoids and salival inmunoglobuline A on paediatric patients with chronic rhinosinusitis without nasal polyps (CRSsNP) and adenoid hypertrophy.
  
  
  METHODS
  Adenoid tissue, liquid obtained from antral lavages and saliva from 28 children diagnosed with CRSsNP, from the paediatric otorhinolaryngology practice of "Dr. Domingo Luciani" Hospital was taken and processed by means of polymerase chain reaction (PCR) using cagA, vacA and babA primers, also anatomopathological examination using Giemsa stain of the adenoids, determination of salivary specific secretory inmunoglobuline A (sIgA), socio-economic condition using the Graffar scale and associated gastrointestinal symptoms were assessed.
  
  
  RESULTS
  No evidence of Helicobacter pylori neither in antral lavages liquid nor adenoid tissue was found using PCR and Giemsa stain. sIgA was present in 28.6% of the subjects. The most frequently found symptoms were, diarrhea in 17.9%, distension and abdominal pain in 10.7%, 64.3% of the patients were in working (28.6%) and low middle (35.7%) classes.
  
  
  CONCLUSIONS
  Helicobacter pylori is not present neither in maxillary sinuses nor adenoid tissue of the evaluated patients, sIgA it is a non-invasive method for assessment of immunologic challenge with the bacteria, not the presence of acute or chronic infection.
authors.affiliation: Venezuelan Foundation of Otology, Caracas, Venezuela. Electronic address: eleazargrateron@hotmail.com.
authors.forename: Eleazar E Graterón
authors.initials: EE
authors.lastname: Cedeño
authors.affiliation: Laboratory of Molecular Microbiology, Dr. Jacinto Convit Institute of Biomedicine Autonomous Service, Caracas, Venezuela.
authors.forename: Diana
authors.initials: D
authors.lastname: Ortiz-Princz
authors.affiliation: Venezuelan Foundation of Otology, Caracas, Venezuela.
authors.forename: Sinay A Ceballos
authors.initials: SA
authors.lastname: Figueredo
authors.affiliation: Laboratory of Molecular Microbiology, Dr. Jacinto Convit Institute of Biomedicine Autonomous Service, Caracas, Venezuela.
authors.forename: María Eugenia Cavazza
authors.initials: ME
authors.lastname: Porro
mesh_terms: D015746:Abdominal Pain / Q000382:microbiology; D000234:Adenoids / Q000382:microbiology* / Q000473:pathology*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003967:Diarrhea / Q000382:microbiology; D005260:Female; D005751:Gastric Lavage; D016481:Helicobacter Infections / Q000150:complications* / Q000276:immunology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D006984:Hypertrophy / Q000473:pathology; D007070:Immunoglobulin A / Q000378:metabolism*; D008297:Male; D008443:Maxillary Sinus / Q000382:microbiology*; D011706:Pyloric Antrum / Q000382:microbiology*; D012220:Rhinitis / Q000382:microbiology; D012463:Saliva / Q000276:immunology*; D012852:Sinusitis / Q000382:microbiology; D012923:Social Class
chemical_list: D007070:Immunoglobulin A
keywords: Adenoid hypertrophy; Antral lavages; Chronic rhinosinusitis; Helicobacter pylori; Inmunoglobuline A