title: Attraction by repulsion: compounds with like charges undergo self-assembly in water that improves in high salt and persists in real biological fluids.
abstract: We report a family of highly anionic calixarenes that form discrete homo-dimeric assemblies in pure water, that get stronger in high salt solutions, and that remain assembled in complex, denaturing solutions like real urine. The results reveal the potential of like-charged subunits for self-assembly in high-salt solutions and biological fluids.
authors.affiliation: Department of Chemistry, University of Victoria, PO Box 3065, STN CSC, Victoria, V8W 3V6, Canada. fhof@uvic.ca.
authors.forename: Graham A E
authors.initials: GA
authors.lastname: Garnett
authors.affiliation: Department of Chemistry, University of Victoria, PO Box 3065, STN CSC, Victoria, V8W 3V6, Canada. fhof@uvic.ca.
authors.forename: Kevin D
authors.initials: KD
authors.lastname: Daze
authors.affiliation: Department of Chemistry, University of Victoria, PO Box 3065, STN CSC, Victoria, V8W 3V6, Canada. fhof@uvic.ca.
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Peña Diaz
authors.affiliation: Department of Chemistry, University of Victoria, PO Box 3065, STN CSC, Victoria, V8W 3V6, Canada. fhof@uvic.ca.
authors.forename: Noah
authors.initials: N
authors.lastname: Fagen
authors.affiliation: Department of Chemistry, University of Victoria, PO Box 3065, STN CSC, Victoria, V8W 3V6, Canada. fhof@uvic.ca.
authors.forename: Alok
authors.initials: A
authors.lastname: Shaurya
authors.affiliation: Department of Chemistry, University of Victoria, PO Box 3065, STN CSC, Victoria, V8W 3V6, Canada. fhof@uvic.ca.
authors.forename: Manuel C F
authors.initials: MC
authors.lastname: Ma
authors.affiliation: Department of Chemistry & Biochemistry, University of Oregon, Eugene, Oregon 97403-1253, USA.
authors.forename: Mary S
authors.initials: MS
authors.lastname: Collins
authors.affiliation: Department of Chemistry & Biochemistry, University of Oregon, Eugene, Oregon 97403-1253, USA.
authors.forename: Darren W
authors.initials: DW
authors.lastname: Johnson
authors.affiliation: Center for Advanced Materials Characterization in Oregon (CAMCOR), 1241 University of Oregon, Eugene, OR 97403-1241, USA.
authors.forename: Lev N
authors.initials: LN
authors.lastname: Zakharov
authors.affiliation: Department of Chemistry, University of Victoria, PO Box 3065, STN CSC, Victoria, V8W 3V6, Canada. fhof@uvic.ca.
authors.forename: Fraser
authors.initials: F
authors.lastname: Hof
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D012492:Salts / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D012492:Salts; D014867:Water