title: Pulpal Remineralisation of Artificial Residual Caries Lesions in vitro.
abstract: We assessed pulpal remineralisation of caries lesions in vitro. On the coronal aspect of human dentin discs (n = 70), artificial lesions [mineral loss x0394;Z (mean ± SD) = 3,060 ± 604 vol% × µm] were induced, covered and pulpal surfaces exposed to pulpal fluid, remineralisation medium or water at pressures of 0, 1.47 or 2.94 kPa for 3 months. Mineral loss differences were assessed using transversal microradiography. No significant mineral gain occurred at 0 kPa and in samples exposed to water. At 1.47 and 2.94 kPa, pulpal and remineralisation fluid induced significant mineral gain [x0394;x0394;Z = 1,317 (25th/75th percentiles: 735/1,541) vol% × µm; p < 0.001]. Pressure and fluid composition determined pulpal remineralisation in vitro.
authors.affiliation: Department of Operative and Preventive Dentistry, Charitx00E9; - Universitx00E4;tsmedizin Berlin, Berlin, Germany.
authors.forename: Falk
authors.initials: F
authors.lastname: Schwendicke
authors.forename: Allam
authors.initials: A
authors.lastname: Al-Abdi
authors.forename: Hendrik
authors.initials: H
authors.lastname: Meyer-Lückel
authors.forename: Sebastian
authors.initials: S
authors.lastname: Paris
mesh_terms: D002327:Cariostatic Agents; D003731:Dental Caries / Q000188:drug therapy; D003804:Dentin; D006801:Humans; D008852:Microradiography; D014089:Tooth Remineralization
chemical_list: D002327:Cariostatic Agents