title: Neuropsychological and psychiatric aspects of multiple sclerosis: preliminary investigation of discrete profiles across neurological subtypes.
abstract: Cognitive deficits affecting memory, attention, speed of information processing and executive functions are common in multiple sclerosis (MS). In this study we examine the possibility of discrete pattern of neuropsychological deficits of MS subtypes. 28 patients (13 RRMS, 6 CIS, and 9 SPMS) were assessed with a comprehensive neuropsycholgical battery. Results indicate that only the SPMS group demonstrates memory and executive impairment. This finding indicates possible differentiation of the three subtypes in terms of neuropsychological profiles. Psychiatric aspects of MS are also briefly discussed.
authors.affiliation: 2nd Neurology Department, Attikon Hospital, National and Kapodistrian University of Athens, Athens, Greece.|1st Neurology Department, Eginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Marina
authors.initials: M
authors.lastname: Katsari
authors.affiliation: 1st Neurology Department, Eginition Hospital, National and Kapodistrian University of Athens, Athens, Greece. dkasselimis@gmail.com.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Kasselimis
authors.affiliation: 2nd Neurology Department, Attikon Hospital, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Gerasimos
authors.initials: G
authors.lastname: Gasparinatos
authors.affiliation: 2nd Neurology Department, Attikon Hospital, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Roubina
authors.initials: R
authors.lastname: Antonellou
authors.affiliation: 2nd Neurology Department, Attikon Hospital, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Voumvourakis
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D056344:Executive Function / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000209:etiology*; D001523:Mental Disorders / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000145:classification* / Q000150:complications*; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D055815:Young Adult
keywords: Executive functions; MS subtypes; Memory; Multiple sclerosis