title: Neuroendoscopic stent placement for cerebrospinal fluid pathway obstructions in adults.
abstract: OBJECTIVE Since its revival in the early 1990s, neuroendoscopy has become an integral component of modern neurosurgery. Endoscopic stent placement for treatment of CSF pathway obstruction is a rarely used and underestimated procedure. The authors present the first series of neuroendoscopic intracranial stenting for CSF pathway obstruction in adults with associated results and complications spanning a long-term follow-up of 20 years. METHODS The authors retrospectively reviewed a prospectively maintained clinical database for endoscopic stent placement performed in adults between 1993 and 2013. RESULTS Of 526 endoscopic intraventricular procedures, stents were placed for treatment of CSF disorders in 25 cases (4.8%). The technique was used in the management of arachnoid cysts (ACs; n = 8), tumor-related CSF disorders (n = 13), and hydrocephalus due to stenosis of the foramen of Monro (n = 2) or aqueduct (n = 2). The mean follow-up was 87.1 months. No deaths or infections occurred that were related to endoscopic placement of intracranial stents. Late stent dislocation or migration was observed in 3 patients (12%). CONCLUSIONS Endoscopic intracranial stent placement in adults is rarely required but is a safe and helpful technique in select cases. It is indicated when reliable and long-lasting restoration of CSF pathway obstructions cannot be achieved with standard endoscopic techniques. In the treatment of tumor-related hydrocephalus, it is a good option to avoid reclosure of the restored CSF pathway by tumor growth. Currently, routine stent placement after endoscopic fenestration of ACs is not recommended. Stent placement for treatment of CSF disorders due to tumor is a good option for avoiding CSF shunting. To avoid stent migration and dislocation, and to allow for easy removal if needed, the device should be fixed to a bur hole reservoir.
authors.affiliation: Department of Neurosurgery, University Medicine Greifswald, Germany;
authors.forename: Sascha
authors.initials: S
authors.lastname: Marx
authors.affiliation: Department of Neurosurgery, University Medicine Greifswald, Germany;
authors.forename: Steffen K
authors.initials: SK
authors.lastname: Fleck
authors.affiliation: Department of Neurosurgery, University Medicine Greifswald, Germany;|Department of Neurosurgery, Kasr Alainy Research and Teaching Hospital, Cairo University, Egypt;
authors.forename: Ehab
authors.initials: E
authors.lastname: El Refaee
authors.affiliation: Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida; and.
authors.forename: Jotham
authors.initials: J
authors.lastname: Manwaring
authors.affiliation: Department of Neurosurgery, University Medicine Greifswald, Germany;
authors.forename: Christina
authors.initials: C
authors.lastname: Vorbau
authors.affiliation: Department of Neurosurgery, University Medicine Greifswald, Germany;
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Fritsch
authors.affiliation: Hannover, Germany.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Gaab
authors.affiliation: Department of Neurosurgery, University Medicine Greifswald, Germany;
authors.forename: Henry W S
authors.initials: HW
authors.lastname: Schroeder
authors.affiliation: Department of Neurosurgery, University Medicine Greifswald, Germany;
authors.forename: Joerg
authors.initials: J
authors.lastname: Baldauf
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D044583:Neuroendoscopy; D012189:Retrospective Studies; D015607:Stents; D014696:Ventriculostomy; D055815:Young Adult
keywords: AC = arachnoid cyst; CSF disorders; ETV = endoscopic third ventriculostomy; hydrocephalus; intracranial stenting; neuroendoscopy