title: Radiofrequency Ablation in Treating Colorectal Cancer Patients with Liver Metastases.
abstract: OBJECTIVE
  To evaluate efficacy of radiofrequency ablation (RFA) in treating colorectal cancer patients with liver metastases.
  
  
  METHODS
  During January 2010 to April 2012, 56 colorectal cancer patients with liver metastases underwent RFA. CT scans were obtained one month after RFA for all patients to evaluate tumor response. (CR+PR+SD)/n was used to count the disease control rates (DCR). Survival data of 1, 2 and 3 years were obtained from follow up.
  
  
  RESULTS
  Patients were followed for 10 to 40 months after RFA (mean time, 25±10 months). Median survival time was 27 months. The 1, 2, 3 year survival rate were 80.4%, 71.4%, 41%, 1 % respectively. 3-year survival time for patients with CR or PR after RFA was 68.8% and 4.3% respectively, the difference was statistically significant. The number of CR, PR, SD and PD in our study was 13, 23, 11 and 9 respectively.
  
  
  CONCLUSIONS
  RFA could be an effective method for treating colorectal cancer patients with liver metastases, and prolong survival time, especially for metastatic lesions less than or equal to 3 cm. But this result should be confirmed by randomized controlled studies.
authors.affiliation: Department of Interventional Radiology, Subei People's Hospital of Jiangsu Province, Clinical Hospital of Yangzhou University, Yangzhou, China E-mail : huangxinen06@163.com; why77@sina.com.
authors.forename: Chuan
authors.initials: C
authors.lastname: Xu
authors.forename: Xin-En
authors.initials: XE
authors.lastname: Huang
authors.forename: Peng-Hua
authors.initials: PH
authors.lastname: Lv
authors.forename: Shu-Xiang
authors.initials: SX
authors.lastname: Wang
authors.forename: Ling
authors.initials: L
authors.lastname: Sun
authors.forename: Fu-An
authors.initials: FA
authors.lastname: Wang
mesh_terms: D017115:Catheter Ablation; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate