title: Clinical Outcome of Hydroxyapatite Coated, Bioactive Glass Coated, and Machined Ti6Al4V Threaded Dental Implant in Human Jaws: A Short-Term Comparative Study.
abstract: BACKGROUND
  Growing aspect of endosseous implant research is focused on surface modification of dental implants for the purpose of improving osseointegration. The aim of this study was to evaluate and compare the clinical outcome (ie, osseointegration) of hydroxyapatite coated, bioactive glass coated and machined titanium alloy threaded dental implants in human jaw bone after implantation.
  
  
  METHODS
  One hundred twenty-six implants (45 hydroxyapatite coated, 41 bioactive glass coated, and 40 machined titanium implants) have been placed in incisor areas of 62 adult patients. Outcome was assessed up to 12 months after prosthetic rehabilitation using different clinical and radiological parameters. Surface roughness of failed implants was analyzed by laser profilometer.
  
  
  CONCLUSIONS
  Hydroxyapatite and bioactive glass coating materials were nontoxic and biocompatible. Least marginal bone loss in radiograph, significantly higher (P < 0.05) interface radiodensity, and less interfacial gaps were observed in computed tomography with bioactive glass coated implants at anterior maxilla compared to other 2 types.
  
  
  CONCLUSIONS
  Bioactive glass coated implants are equally safe and effective as hydroxyapatite coated and machined titanium implants in achieving osseointegration; therefore, can be effectively used as an alternative coating material for dental implants.
authors.affiliation: *Assistant Professor, Department of Periodontics, Burdwan Dental College, West Bengal, India. †Associate Professor, Department of Orthopaedics, Calcutta National Medical College, Kolkata, West Bengal, India. ‡Scientist, Bioceramics and Coating Division, CSIR-Central Glass and Ceramic Research Institute, West Bengal, India. §Senior Lecturer, Department of Periodontics, Institute of Dental Sciences, SOA University, Bhubaneswar, India. ¶Associate Professor, School of Bio-Science and Engineering, Jadavpur University, West Bengal, India. ‖Professor, Department of Periodontics, Awadh Dental College and Hospital, Jamshedpur, India.
authors.forename: Surajit
authors.initials: S
authors.lastname: Mistry
authors.forename: Rajiv
authors.initials: R
authors.lastname: Roy
authors.forename: Biswanath
authors.initials: B
authors.lastname: Kundu
authors.forename: Someswar
authors.initials: S
authors.lastname: Datta
authors.forename: Manoj
authors.initials: M
authors.lastname: Kumar
authors.forename: Abhijit
authors.initials: A
authors.lastname: Chanda
authors.forename: Debabrata
authors.initials: D
authors.lastname: Kundu
mesh_terms: D000293:Adolescent; D000328:Adult; D000497:Alloys; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D019232:Dental Restoration Failure; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D005898:Glass; D006801:Humans; D008297:Male; D008334:Mandible; D008875:Middle Aged; D016348:Osseointegration / Q000187:drug effects; D014025:Titanium / Q000627:therapeutic use; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000497:Alloys; D015921:Dental Implants; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium