title: Metal-Free CH-CH-Type Cross-Coupling of Arenes and Alkynes Directed by a Multifunctional Sulfoxide Group.
abstract: A metal-free CH-CH-type coupling of arenes and alkynes, mediated by a multifunctional sulfoxide directing group, exploits nonprefunctionalized coupling partners, proceeds under mild conditions, is operationally simple, and exhibits high functional group tolerance. The products of the CH-CH coupling are highly versatile, and the metal-free process can be used for the construction and late-stage modification of important molecular scaffolds.
authors.affiliation: School of Chemistry, University of Manchester , Oxford Road, Manchester, M13 9PL, U.K.
authors.forename: José A
authors.initials: JA
authors.lastname: Fernández-Salas
authors.affiliation: School of Chemistry, University of Manchester , Oxford Road, Manchester, M13 9PL, U.K.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Eberhart
authors.affiliation: School of Chemistry, University of Manchester , Oxford Road, Manchester, M13 9PL, U.K.
authors.forename: David J
authors.initials: DJ
authors.lastname: Procter