title: Capecitabine-Induced Severe Toxicity Secondary to DPD Deficiency and Successful Treatment with Low Dose 5-Fluorouracil.
authors.affiliation: Department of Internal Medicine, University of Massachusetts Medical School, Worcester, MA, USA.
authors.forename: Saranya
authors.initials: S
authors.lastname: Kodali
authors.affiliation: Department of Medicine, Division of Hematology and Oncology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA.
authors.forename: Venu
authors.initials: V
authors.lastname: Bathini
authors.affiliation: Department of Radiation Oncology, University of Massachusetts Medical School, Worcester, MA, USA.
authors.forename: Paul
authors.initials: P
authors.lastname: Rava
authors.affiliation: Department of Medicine, Division of Hematology and Oncology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA. eswar.tipirneni@gmail.com.
authors.forename: Eswar
authors.initials: E
authors.lastname: Tipirneni
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects / Q000627:therapeutic use; D000069287:Capecitabine / Q000009:adverse effects* / Q000627:therapeutic use; D054067:Dihydropyrimidine Dehydrogenase Deficiency / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000378:metabolism
chemical_list: D000964:Antimetabolites, Antineoplastic; D000069287:Capecitabine; D005472:Fluorouracil