title: Changes in platelet function following cold storage of RBC suspensions.
abstract: OBJECTIVE
  To provide a basis for the cold-storage of human platelets as a way to assess changes in platelet function.
  
  
  METHODS
  Red blood cell suspensions (11 U and 50 U) were randomly selected at different storage times (3-28 days) and evidence of platelet activation (CD62P) and thromboelastography (TEG) reaction times were investigated.
  
  
  RESULTS
  After 21 days of storage at 4°C, a large number of activated platelets (PAC1+62P+, PAC1-62P+) within the red blood cell suspension (RBCs) retained their function and had TEG-maximum amplitude (TEG-MA) indices in the normal range.
  
  
  CONCLUSIONS
  We report that platelets in RBC suspensions retain high activity when stored at 4°C for 21 days. The results provide important information for studies that involve storing platelets under cold conditions.
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an 710068, China.
authors.forename: Qian-Li
authors.initials: QL
authors.lastname: Dang
authors.affiliation: Department of Transfusion Medicine, Xi'an No. 4 Hospital Xi'an 710004, China.
authors.forename: Jian-Gang
authors.initials: JG
authors.lastname: Li
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an 710068, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Sun
authors.affiliation: The Second Department of Orthopaedics, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an 710068, China.
authors.forename: Zhan-Kui
authors.initials: ZK
authors.lastname: Jin
authors.affiliation: Department of Hematology, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an 710068, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Shaanxi Provincial Center for Clinical Laboratory, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an 710068, China.
authors.forename: Cui-Xiang
authors.initials: CX
authors.lastname: Xu
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an 710068, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Chen
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an 710068, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Ma
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an 710068, China.
authors.forename: Jiang-Cun
authors.initials: JC
authors.lastname: Yang
keywords: RBC suspensions; blood platelets; cold storage; hemostasis; thromboelastography