title: Autologous stem-cell transplantation for multiple myeloma: a Brazilian institution experience in 15 years of follow-up.
abstract: OBJECTIVE
  To determine the 5-year post-transplant survival of patients with multiple myeloma.
  
  
  METHODS
  A retrospective study in patients diagnosed with multiple myeloma submitted to autologous bone marrow transplantation at a Brazilian institution, during the period of 1993 to 2007.
  
  
  RESULTS
  Seventy-three patients were evaluated with a median age of 55 years. Survival in 5 years was 75% (2.4 to 60 months). Statistical analysis demonstrated statistical significance for the applied grade of response prior to treatment with autologous bone marrow transplantation (p = 0.01). There was no statistical significance for clinical staging or time of diagnosis (before or after the year 2000).
  
  
  CONCLUSIONS
  Experience in autologous bone marrow transplantation for multiple myeloma at a Brazilian institution demonstrated an evolution consistent with that of medical literature and highlighted the importance of a response to treatment prior to transplantation in the survival of these patients.
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
authors.forename: Juliana
authors.initials: J
authors.lastname: Todaro
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
authors.forename: Ana Rita de Araújo Burgos
authors.initials: AR
authors.lastname: Manhani
authors.affiliation: Blood Bank, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
authors.forename: José Mauro
authors.initials: JM
authors.lastname: Kutner
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
authors.forename: Andreza Alice Feitosa
authors.initials: AA
authors.lastname: Ribeiro
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, BR.
authors.forename: Morgani
authors.initials: M
authors.lastname: Rodrigues
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, BR.
authors.forename: Fabio Rodrigues
authors.initials: FR
authors.lastname: Kerbauy
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, BR.
authors.forename: Jairo Nascimento
authors.initials: JN
authors.lastname: Sobrinho
authors.affiliation: Hospital Pequeno Príncipe, Curitiba, PR, BR.
authors.forename: Eurípedes
authors.initials: E
authors.lastname: Ferreira
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, BR.
authors.forename: Nelson
authors.initials: N
authors.lastname: Hamerschlak