title: [Inflammatory heart diseases--cardiac sarcoidosis and giant cell myocarditis].
abstract: The most common symptoms of cardiac sarcoidosis and giant cell myocarditis are atrioventricular block, ventricular tachycardia and cardiac insufficiency. Magnetic resonance imaging of the heart or positron emission tomography are utilized to evaluate the possibility of inflammatory heart disease. The diagnosis is based on histologic examination of a cardiac muscle tissue specimen. For both diseases, the increase in the number of diagnoses is likely to be due to improved diagnostics. The cause of cardiac sarcoidosis is not known, but granulomatous inflammation can be suppressed with corticosteroids. In giant cell myocarditis, more powerful immunosuppression is utilized than in sarcoidosis, but one third of the patients still require heart transplantation within one year from the diagnosis.
authors.forename: Jukka
authors.initials: J
authors.lastname: Lehtonen
authors.forename: Riina
authors.initials: R
authors.lastname: Kandolin
authors.forename: Markku
authors.initials: M
authors.lastname: Kupari
mesh_terms: D009202:Cardiomyopathies / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D015726:Giant Cells / Q000473:pathology*; D006801:Humans; D009205:Myocarditis / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D012507:Sarcoidosis / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy