title: Prevalence and Antimicrobial Resistance of Campylobacterjejuni and Campylobacter coli from Adult Hospitalized Patients with Diarrhea in Thailand.
abstract: BACKGROUND
  Infection with Campylobacter jejuni and C. coli are recognized as the major cause of bacterial gastroenteritis in humans.
  
  
  METHODS
  A total of 310 fecal samples collected from Thai adult patients with diarrhea in 2008 were screened for the presence of Campylobacter by PCR. Resistance to fluoroquinolone and macrolides of the detected Campylobacter strains were analyzed by studying the mutations in the gyrA and 23S rRNA genes, respectively.
  
  
  RESULTS
  Campylobacter species were detected in 4/310 (1.3%) of diarrheal patients, and C. jejuni was found in 3 of the 4 cases (75%). Fluoroquinolone resistance was noted in 2 cases (50%); however, no resistance to macrolides was observed.
  
  
  CONCLUSIONS
  Campylobacter was detected in a low prevalence in adult Thai patients hospitalized with diarrhea, and the resistance to fluoroquinolones is still a matter of concern in case antibiotic therapy is required.
authors.forename: Ngan Thi Kim
authors.initials: NT
authors.lastname: Pham
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ushijima
authors.forename: Quang Duy
authors.initials: QD
authors.lastname: Trinh
authors.forename: Pattara
authors.initials: P
authors.lastname: Khamrin
authors.forename: Shihoko
authors.initials: S
authors.lastname: Komine-Aizawa
authors.forename: Shoko
authors.initials: S
authors.lastname: Okitsu
authors.forename: Niwat
authors.initials: N
authors.lastname: Maneekarn
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hayakawa
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001483:Base Sequence; D017000:Campylobacter coli / Q000187:drug effects / Q000302:isolation & purification*; D016123:Campylobacter jejuni / Q000187:drug effects / Q000302:isolation & purification*; D003967:Diarrhea / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D006760:Hospitalization; D006801:Humans; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D013785:Thailand / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents