title: Singapore Cancer Network (SCAN) Guidelines for the Initial Evaluation, Diagnosis, and Management of Extremity Soft Tissue Sarcoma and Osteosarcoma.
abstract: BACKGROUND
  The SCAN sarcoma workgroup aimed to develop Singapore Cancer Network (SCAN) clinical practice guidelines for the initial evaluation, diagnosis, and management of extremity soft tissue sarcoma and osteosarcoma.
  
  
  METHODS
  The workgroup utilised a consensus approach to create high quality evidence-based clinical practice guidelines suited for our local setting.
  
  
  RESULTS
  Various international guidelines from the fields of radiology, pathology, orthopaedic surgery, medical, radiation and paediatric oncology were reviewed, including those developed by von Mehren Metal (J Natl Compr Canc Netw 2014), the National Collaborating Centre for Cancer (2006), the European Sarcoma Network Working Group (2012) and Grimer RJ et al (Sarcoma 2008). Our clinical practice guidelines contextualised to the local patient will streamline care and improve clinical outcomes for patients with extremity soft tissue and osteosarcoma.
  
  
  CONCLUSIONS
  These guidelines form the SCAN Guidelines 2015 for the initial evaluation, diagnosis, and management of extremity soft tissue sarcoma and osteosarcoma.
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D002648:Child; D002945:Cisplatin / Q000008:administration & dosage; D019468:Disease Management; D004317:Doxorubicin / Q000008:administration & dosage; D005121:Extremities / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D008727:Methotrexate / Q000008:administration & dosage; D020360:Neoadjuvant Therapy; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D000072078:Positron Emission Tomography Computed Tomography; D049268:Positron-Emission Tomography; D011878:Radiotherapy; D018714:Radiotherapy, Adjuvant; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D012846:Singapore; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D013514:Surgical Procedures, Operative; D014057:Tomography, X-Ray Computed
chemical_list: D004317:Doxorubicin; D002945:Cisplatin; D007069:Ifosfamide; D008727:Methotrexate