title: Report of the Inaugural Meeting of the TFOS i(2) = initiating innovation Series: Targeting the Unmet Need for Dry Eye Treatment.
abstract: On March 21, 2015, a meeting was held in London, United Kingdom, to address the progress in targeting the unmet need for dry eye disease (DED) treatment. The meeting, which launched the i(2) = initiating innovation series, was sponsored by the Tear Film & Ocular Surface Society (TFOS; www.TearFilm.org) and supported by Dompé. The TFOS i(2) meeting was designed to review advances in the understanding of DED since publication of the 2007 TFOS International Dry Eye WorkShop (DEWS) report, and to help launch the highly anticipated sequel, DEWS II. The meeting was structured to discuss the scope of the DED problem, to review the clinical challenges of DED, and to consider the treatment challenges of DED. This article provides a synopsis of the presentations of this TFOS i(2) meeting.
authors.affiliation: Schepens Eye Research Institute, Massachusetts Eye and Ear and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
authors.forename: Wendy
authors.initials: W
authors.lastname: Chao
authors.affiliation: Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas, and International Brain Research Organization, Alicante, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Belmonte
authors.affiliation: Complutense University of Madrid and Hospital Clinico San Carlos, Madrid, Spain.
authors.forename: José M
authors.initials: JM
authors.lastname: Benitez Del Castillo
authors.affiliation: University of Oxford, Oxford, UK.
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Bron
authors.affiliation: Section of Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
authors.forename: Harminder S
authors.initials: HS
authors.lastname: Dua
authors.affiliation: School of Optometry, University of Alabama, Birmingham, AL, USA.
authors.forename: Kelly K
authors.initials: KK
authors.lastname: Nichols
authors.affiliation: PharmaLogic Development, Inc., San Rafael, CA, USA.
authors.forename: Gary D
authors.initials: GD
authors.lastname: Novack
authors.affiliation: Laboratory for Experimental Ophthalmology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Schrader
authors.affiliation: School of Optometry and Vision Science, University of New South Wales, Sydney, NSW, Australia.
authors.forename: Mark D
authors.initials: MD
authors.lastname: Willcox
authors.affiliation: Ophthalmic Research Group, Life and Health Sciences, Aston University, Birmingham, UK.
authors.forename: James S
authors.initials: JS
authors.lastname: Wolffsohn
authors.affiliation: Schepens Eye Research Institute, Massachusetts Eye and Ear and Department of Ophthalmology, Harvard Medical School, Boston, MA, USA. Electronic address: david.sullivan@schepens.harvard.edu.
authors.forename: David A
authors.initials: DA
authors.lastname: Sullivan
mesh_terms: D015352:Dry Eye Syndromes; D005123:Eye; D006801:Humans; D007638:Keratoconjunctivitis Sicca; D012955:Societies, Medical; D013666:Tears
keywords: Clinical trials; Dry Eye WorkShop II (DEWS II); Tear Film & Ocular Surface Society; drug development; dry eye disease (DED); i(2) = initiating innovation series