title: Bone marrow invasion in multiple myeloma and metastatic disease.
abstract: Magnetic resonance imaging (MRI) of the spine is the imaging study of choice for the management of bone marrow disease. MRI sequences enable us to integrate structural and functional information for detecting, staging, and monitoring the response the treatment of multiple myeloma and bone metastases in the spine. Whole-body MRI has been incorporated into different guidelines as the technique of choice for managing multiple myeloma and metastatic bone disease. Normal physiological changes in the yellow and red bone marrow represent a challenge in analyses to differentiate clinically significant findings from those that are not clinically significant. This article describes the findings for normal bone marrow, variants, and invasive processes in multiple myeloma and bone metastases.
authors.affiliation: Unidad de Resonancia Magnética, Clínica Girona, Girona, España. Servicio de Radiodiagnóstico, IDI, Institut de Diagnòstic per la Imatge, Institut Català de la Salut, Girona, España. Departamento de Ciencias Médicas, Facultad de Medicina, Universidad de Girona, Girona, España. Electronic address: kvilanova@comg.cat.
authors.forename: J C
authors.initials: JC
authors.lastname: Vilanova
authors.affiliation: Servicio de Radiología, Clínica Las Nieves, SERCOSA (Grupo Health Time), Jaén, España.
authors.forename: A
authors.initials: A
authors.lastname: Luna
mesh_terms: D019046:Bone Marrow Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D006801:Humans; D009101:Multiple Myeloma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000556:secondary*; D009361:Neoplasm Invasiveness; D013120:Spinal Cord Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*
keywords: Bone marrow; Columna vertebral; Diffusion; Difusión; Magnetic resonance; Metastases; Metástasis; Médula ósea; Resonancia magnética; Spinal column