title: Cell Proliferation in Neuroblastoma.
abstract: Neuroblastoma, the most common extracranial solid tumor of childhood, continues to carry a dismal prognosis for children diagnosed with advanced stage or relapsed disease. This review focuses upon factors responsible for cell proliferation in neuroblastoma including transcription factors, kinases, and regulators of the cell cycle. Novel therapeutic strategies directed toward these targets in neuroblastoma are discussed.
authors.affiliation: Department of Surgery, Division of Pediatric Surgery, University of Alabama, Birmingham, AL 35233, USA. lstafman@uabmc.edu.
authors.forename: Laura L
authors.initials: LL
authors.lastname: Stafman
authors.affiliation: Department of Surgery, Division of Pediatric Surgery, University of Alabama, Birmingham, AL 35233, USA. elizabeth.beierle@childrensal.org.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Beierle
keywords: MYCN; cell cycle check point inhibitors; kinases; neuroblastoma