title: [Human brown adipose tissue].
abstract: Adult humans have heat-producing and energy-consuming brown adipose tissue in the clavicular region of the neck. There are two types of brown adipose cells, the so-called classic and beige adipose cells. Brown adipose cells produce heat by means of uncoupler protein 1 (UCP1) from fatty acids and sugar. By applying positron emission tomography (PET) measuring the utilization of sugar, the metabolism of brown fat has been shown to multiply in the cold, presumably influencing energy consumption. Active brown fat is most likely present in young adults, persons of normal weight and women, least likely in obese persons.
authors.forename: Kirsi A
authors.initials: KA
authors.lastname: Virtanen
authors.forename: Pirjo
authors.initials: P
authors.lastname: Nuutila
mesh_terms: D002001:Adipose Tissue, Brown / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D000328:Adult; D004734:Energy Metabolism; D006801:Humans; D007473:Ion Channels / Q000502:physiology*; D024101:Mitochondrial Proteins / Q000502:physiology*; D009333:Neck; D049268:Positron-Emission Tomography; D000071256:Uncoupling Protein 1
chemical_list: D007473:Ion Channels; D024101:Mitochondrial Proteins; C000604371:UCP1 protein, human; D000071256:Uncoupling Protein 1