title: Sleep Variability Among Older Adults With Insomnia: Associations With Sleep Quality and Cardiometabolic Disease Risk.
abstract: Sleep variability has been linked to poor subjective sleep quality, but few studies have investigated effects on physical health. In this study, we evaluated cross sectional associations and change over time in objective sleep variability of adults with insomnia and short sleep duration who were participating in a non-pharmacologic intervention study. Results indicated greater variability in objective sleep measures were associated with poorer subjective sleep quality (p < 0.05). Higher sleep duration variability was associated with higher HbA1c (p < 0.01) and sleep onset time variability was associated with higher BMI (p < 0.05). Sleep efficiency and WASO variability decreased with intervention (p < 0.05). These results indicate that objective sleep variability may be an important feature for the assessment of insomnia outcomes.
authors.affiliation: a Department of Neurology , Northwestern University , Chicago , Illinois.
authors.forename: Kelly Glazer
authors.initials: KG
authors.lastname: Baron
authors.affiliation: b Feinberg School of Medicine , Northwestern University , Chicago , Illinois.
authors.forename: Kathryn J
authors.initials: KJ
authors.lastname: Reid
authors.affiliation: b Feinberg School of Medicine , Northwestern University , Chicago , Illinois.
authors.forename: Roneil G
authors.initials: RG
authors.lastname: Malkani
authors.affiliation: b Feinberg School of Medicine , Northwestern University , Chicago , Illinois.
authors.forename: Joseph
authors.initials: J
authors.lastname: Kang
authors.affiliation: b Feinberg School of Medicine , Northwestern University , Chicago , Illinois.
authors.forename: Phyllis C
authors.initials: PC
authors.lastname: Zee
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000209:etiology / Q000503:physiopathology; D003430:Cross-Sectional Studies; D004198:Disease Susceptibility; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000209:etiology / Q000503:physiopathology; D012890:Sleep / Q000502:physiology*; D007319:Sleep Initiation and Maintenance Disorders / Q000150:complications / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human