title: Age, weight and decompression sickness in rats.
abstract: OBJECTIVE
  The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats.
  
  
  METHODS
  Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile.
  
  
  RESULTS
  In this experiment, there was a clear difference between DCS outcome at ages 11 or 13 weeks in matched rats (p = 0.002).
  
  
  CONCLUSIONS
  Even with weight included in the model, age was significantly associated with DCS (p = 0.01), yet after removal of weight the association was much stronger (p = 0.002).
  
  
  CONCLUSIONS
  We believe that age is likely to be found associated with the probability of DCS in a larger dataset with a wider range of parameters, after accounting for the effect of weight.
authors.affiliation: a Laboratoire Optimisation des Régulations Physiologiques (ORPhy) , UFR Sciences et Techniques, Université de Bretagne Occidentale , Brest Cedex , France .|b The School of Sports Science, Exercise and Health, The University of Western Australia , Crawley , WA , Australia , and.
authors.forename: Peter
authors.initials: P
authors.lastname: Buzzacott
authors.affiliation: a Laboratoire Optimisation des Régulations Physiologiques (ORPhy) , UFR Sciences et Techniques, Université de Bretagne Occidentale , Brest Cedex , France .
authors.forename: Michael
authors.initials: M
authors.lastname: Theron
authors.affiliation: a Laboratoire Optimisation des Régulations Physiologiques (ORPhy) , UFR Sciences et Techniques, Université de Bretagne Occidentale , Brest Cedex , France .
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Mazur
authors.affiliation: a Laboratoire Optimisation des Régulations Physiologiques (ORPhy) , UFR Sciences et Techniques, Université de Bretagne Occidentale , Brest Cedex , France .
authors.forename: Qiong
authors.initials: Q
authors.lastname: Wang
authors.affiliation: a Laboratoire Optimisation des Régulations Physiologiques (ORPhy) , UFR Sciences et Techniques, Université de Bretagne Occidentale , Brest Cedex , France .
authors.forename: Kate
authors.initials: K
authors.lastname: Lambrechts
authors.affiliation: c Department of Circulation and Medical Imaging , Norwegian University of Science and Technology , Trondheim , Norway.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Eftedal
authors.affiliation: c Department of Circulation and Medical Imaging , Norwegian University of Science and Technology , Trondheim , Norway.
authors.forename: Simin Berenji
authors.initials: SB
authors.lastname: Ardestani
authors.affiliation: a Laboratoire Optimisation des Régulations Physiologiques (ORPhy) , UFR Sciences et Techniques, Université de Bretagne Occidentale , Brest Cedex , France .
authors.forename: François
authors.initials: F
authors.lastname: Guerrero
mesh_terms: D000375:Aging; D000818:Animals; D001835:Body Weight; D003665:Decompression Sickness / Q000503:physiopathology*; D008297:Male; D051381:Rats; D016019:Survival Analysis
keywords: Decompression illness; Long-Evans; diving; regression modeling