title: Fluorescent MoS2 Quantum Dots: Ultrasonic Preparation, Up-Conversion and Down-Conversion Bioimaging, and Photodynamic Therapy.
abstract: Small size molybdenum disulfide (MoS2) quantum dots (QDs) with desired optical properties were controllably synthesized by using tetrabutylammonium-assisted ultrasonication of multilayered MoS2 powder via OH-mediated chain-like Mo-S bond cleavage mode. The tunable up-bottom approach of precise fabrication of MoS2 QDs finally enables detailed experimental investigations of their optical properties. The synthesized MoS2 QDs present good down-conversion photoluminescence behaviors and exhibit remarkable up-conversion photoluminescence for bioimaging. The mechanism of the emerging photoluminescence was investigated. Furthermore, superior (1)O2 production ability of MoS2 QDs to commercial photosensitizer PpIX was demonstrated, which has great potential application for photodynamic therapy. These early affording results of tunable synthesis of MoS2 QDs with desired photo properties can lead to application in fields of biomedical and optoelectronics.
authors.affiliation: Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology Beijing , Beijing 100083, People's Republic of China.
authors.forename: Haifeng
authors.initials: H
authors.lastname: Dong
authors.affiliation: Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology Beijing , Beijing 100083, People's Republic of China.
authors.forename: Songsong
authors.initials: S
authors.lastname: Tang
authors.affiliation: Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology Beijing , Beijing 100083, People's Republic of China.
authors.forename: Yansong
authors.initials: Y
authors.lastname: Hao
authors.affiliation: Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology Beijing , Beijing 100083, People's Republic of China.
authors.forename: Haizhu
authors.initials: H
authors.lastname: Yu
authors.affiliation: Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology Beijing , Beijing 100083, People's Republic of China.
authors.forename: Wenhao
authors.initials: W
authors.lastname: Dai
authors.affiliation: Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology Beijing , Beijing 100083, People's Republic of China.
authors.forename: Guifeng
authors.initials: G
authors.lastname: Zhao
authors.affiliation: Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology Beijing , Beijing 100083, People's Republic of China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Cao
authors.affiliation: Department of Environmental Science and Engineering, School of Chemistry and Environment, Beijing University of Aeronautics and Astronautics , Beijing 100083, People's Republic of China.
authors.forename: Huiting
authors.initials: H
authors.lastname: Lu
authors.affiliation: Beijing Key Laboratory for Bioengineering and Sensing Technology, Research Center for Bioengineering and Sensing Technology, School of Chemistry & Biological Engineering, University of Science & Technology Beijing , Beijing 100083, People's Republic of China.
authors.forename: Xueji
authors.initials: X
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University , Nanjing 210093, People's Republic of China.
authors.forename: Huangxian
authors.initials: H
authors.lastname: Ju
mesh_terms: D020811:Biomedical Technology; D004396:Coloring Agents / Q000737:chemistry / Q000627:therapeutic use; D004220:Disulfides / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D006801:Humans; D049449:Luminescence; D008982:Molybdenum / Q000737:chemistry* / Q000627:therapeutic use; D036103:Nanotechnology; D010778:Photochemotherapy; D011524:Protoporphyrins / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry* / Q000627:therapeutic use; D000644:Quaternary Ammonium Compounds / Q000737:chemistry
chemical_list: D004396:Coloring Agents; D004220:Disulfides; D011524:Protoporphyrins; D000644:Quaternary Ammonium Compounds; D008982:Molybdenum; C028025:protoporphyrin IX; C009405:tetrabutylammonium; C082964:molybdenum disulfide
keywords: MoS2 quantum dots; bioimaging; photodynamic therapy (PDT); ultrasonic preparation; up-conversion fluorescence