title: Human fallopian tube proteome shows high coverage of mesenchymal stem cells associated proteins.
abstract: The object of this research was to report a draft proteome of human fallopian tube (hFT) comprises 5416 identified proteins, which could be considered as a physiological reference to complement Human Proteome Draft. The proteomic raw data and metadata were stored in an integrated proteome resources centre iProX (IPX00034300). This hFT proteome contains many hFT markers newly identified by mass spectrum. This hFT proteome comprises 660 high-, 3605 medium- and 1181 low-abundant proteins. Ribosome, cytoskeleton, vesicle and protein folding associated proteins showed obvious tendency to be higher abundance in hFT. The extraordinary high coverage of mesenchymal stem cells (MSCs)-associated proteins were identified in this hFT proteome, which highly supported that hFT should contain a plenty of MSCs.
authors.affiliation: Gynecology Department, The First Clinical Medical School, Guangzhou University of Chinese Medicine, 12 Jichang Blvd, Guangzhou 510405, China.
authors.forename: Chenyuan
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Systems Biology for Medicine, Shanghai Medical College, and Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing 102206, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Chang
authors.affiliation: State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing 102206, China.
authors.forename: Songfeng
authors.initials: S
authors.lastname: Wu
authors.affiliation: Gynecology Department, The First Clinical Medical School, Guangzhou University of Chinese Medicine, 12 Jichang Blvd, Guangzhou 510405, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Gao
authors.affiliation: Department of Systems Biology for Medicine, Shanghai Medical College, and Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Gynecology Department, The First Clinical Medical School, Guangzhou University of Chinese Medicine, 12 Jichang Blvd, Guangzhou 510405, China.
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Systems Biology for Medicine, Shanghai Medical College, and Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China denggaopi@126.com zonefan@163.com.
authors.forename: Fan
authors.initials: F
authors.lastname: Zhong
authors.affiliation: Gynecology Department, The First Clinical Medical School, Guangzhou University of Chinese Medicine, 12 Jichang Blvd, Guangzhou 510405, China denggaopi@126.com zonefan@163.com.
authors.forename: Gaopi
authors.initials: G
authors.lastname: Deng
mesh_terms: D000328:Adult; D005187:Fallopian Tubes / Q000378:metabolism*; D005260:Female; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000378:metabolism*; D008875:Middle Aged; D020543:Proteome / Q000378:metabolism*
chemical_list: D020543:Proteome
keywords: human fallopian tube; mesenchymal stem cell; oviduct; proteome