title: [Structural Features of Cysteine-Stabilized Polypeptides from Sea Anemones Venoms].
abstract: Nowadays, venom-based drug discovery becomes popular again: pharmaceutical companies evaluate animal venom potential as a combinatory library of biologically-active compounds. Collaborations with research groups from academia are intensified, new toxins are being investigated, among which polypeptides are of paramount importance. Sea anemones produce the most diversified, from structural point of view, polypep- tide venom components among other animals. This particular review considers known polypeptide toxins from sea anemones, basically taking into account its classification by primary structural features. The most important functional characteristics are analyzed in each structural class.
authors.forename: A N
authors.initials: AN
authors.lastname: Mikov
authors.forename: S A
authors.initials: SA
authors.lastname: Kozlov
mesh_terms: D000818:Animals; D003064:Cnidarian Venoms / Q000737:chemistry* / Q000378:metabolism; D003545:Cysteine / Q000737:chemistry*; D055808:Drug Discovery / Q000379:methods*; D010455:Peptides / Q000737:chemistry / Q000302:isolation & purification*; D011487:Protein Conformation; D012615:Sea Anemones / Q000378:metabolism*
chemical_list: D003064:Cnidarian Venoms; D010455:Peptides; D003545:Cysteine