title: Fluorescent asymmetric bis-ureas for pyrophosphate recognition in pure water.
abstract: Three fluorescent asymmetric bis-urea receptors (L1-L3) have been synthesised. The binding properties of L1-L3 towards different anions (fluoride, acetate, hydrogencarbonate, dihydrogen phosphate, and hydrogen pyrophosphate HPpi(3-)) have been studied by means of (1)H-NMR, UV-Vis and fluorescence spectroscopy, single crystal X-ray diffraction, and theoretical calculations. In particular, a remarkable affinity for HPpi(3-) has been observed in the case L1 (DMSO-d6/0.5% H2O) which also acts as a fluorimetric chemosensor for this anion. Interestingly, when L1 is included in cetyltrimethylammonium (CTAB) micelles, hydrogen pyrophosphate recognition can also be achieved in pure water.
authors.affiliation: Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, S.S. 554 Bivio per Sestu, 09042 Monserrato (CA), Italy. ccaltagirone@unica.it.
authors.forename: Arianna
authors.initials: A
authors.lastname: Casula
authors.forename: Carla
authors.initials: C
authors.lastname: Bazzicalupi
authors.forename: Alexandre
authors.initials: A
authors.lastname: Bettoschi
authors.forename: Enzo
authors.initials: E
authors.lastname: Cadoni
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Coles
authors.forename: Peter N
authors.initials: PN
authors.lastname: Horton
authors.forename: Francesco
authors.initials: F
authors.lastname: Isaia
authors.forename: Vito
authors.initials: V
authors.lastname: Lippolis
authors.forename: Lucy K
authors.initials: LK
authors.lastname: Mapp
authors.forename: Giada M
authors.initials: GM
authors.lastname: Marini
authors.forename: Riccardo
authors.initials: R
authors.lastname: Montis
authors.forename: Mariano Andrea
authors.initials: MA
authors.lastname: Scorciapino
authors.forename: Claudia
authors.initials: C
authors.lastname: Caltagirone
mesh_terms: D011756:Diphosphates / Q000032:analysis*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013050:Spectrometry, Fluorescence; D014508:Urea / Q000737:chemistry*; D014867:Water / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D011756:Diphosphates; D005456:Fluorescent Dyes; D014867:Water; C107241:diphosphoric acid; D014508:Urea