title: CYP2C9 involvement in ACT-453859 metabolism.
authors.affiliation: Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland.
authors.forename: Martine
authors.initials: M
authors.lastname: Géhin
authors.affiliation: Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland.
authors.forename: Jasper
authors.initials: J
authors.lastname: Dingemanse
authors.affiliation: Department of Clinical Pharmacology, Actelion Pharmaceuticals Ltd, Allschwil, Switzerland.
authors.forename: Patricia N
authors.initials: PN
authors.lastname: Sidharta
mesh_terms: D000085:Acetates / Q000008:administration & dosage*; D002227:Carbazoles / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D011971:Receptors, Immunologic / Q000037:antagonists & inhibitors*; D011982:Receptors, Prostaglandin / Q000037:antagonists & inhibitors*
chemical_list: D000085:Acetates; D002227:Carbazoles; D011971:Receptors, Immunologic; D011982:Receptors, Prostaglandin