title: [Optimization of Extraction Technology for Sericin from Silkworm Cocoon with Orthogonal Design].
abstract: OBJECTIVE
  To optimize the appropriate extracting technology for sericin from Silkworm cocoon.
  
  
  METHODS
  Using sericin extraction rates and sericin content as the indices. The single and orthogonal experiments were used to determine the best conditions.
  
  
  RESULTS
  The optimal extraction technology for sericin from Silkworm cocoon was as follows: 1: 30 for the ratio of solid to liquid, 3 h reflux for 2 times of extraction and water temperature at 100 degrees C. The extraction rate of sericin from Silkworm cocoon was 27.1%.
  
  
  CONCLUSIONS
  The optimal extraction technology is stable, feasible, and can provide reference for further pharmacological study on cocoon sericin.
authors.forename: Chun-ying
authors.initials: CY
authors.lastname: Zhao
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Yun-feng
authors.initials: YF
authors.lastname: Li
authors.forename: Zhi-hong
authors.initials: ZH
authors.lastname: Chen
mesh_terms: D000818:Animals; D012831:Bombyx; D047030:Sericins / Q000302:isolation & purification*; D013696:Temperature; D014867:Water
chemical_list: D047030:Sericins; D014867:Water