title: A hypothesis-effect of T cell epitope fusion peptide specific immunotherapy on signal transduction.
abstract: Asthma is a chronic nonspecific inflammatory disease of the airway primarily mediated by different inflammatory cells, including mast cells, eosinophils and T cells. We hereby specially focused on a signal pathway for Janus kinase-signal transducer and activators of transduction (JAK-STATs), which has been the interest of study in asthma since it more likely regulates cellular proliferation and differentiation, and consequently modulates immune system. In our consideration, knowledge on this signal pathway may provide an avenue for rational options in treatment of asthma on control of immune response basis.
authors.affiliation: Department of Medical Parasitology, Wannan Medical College Wuhu 241002, Anhui, P. R. China.
authors.forename: Chao-Pin
authors.initials: CP
authors.lastname: Li
authors.affiliation: Department of Medical Parasitology, Wannan Medical College Wuhu 241002, Anhui, P. R. China.
authors.forename: Bang-He
authors.initials: BH
authors.lastname: Yang
keywords: Allergic asthma; JAK/STAT; signal pathway; specific immunotherapy