title: Cost Effectiveness and Economic Impact of the KineSpring Knee Implant System in the Treatment of Knee Osteoarthritis in Spain.
abstract: We investigated the efficacy and cost effectiveness of the KineSpring System in the Spanish healthcare system, as compared to other standard treatments methods. Cost-utility ratios were calculated using derived cost data and we calculated quality-adjusted life years (QALYs) gained for each method of treatment. Cost-utility ratios were calculated assuming lifetime and 10-year durability. Assuming lifetime durability, cost-utility ratios of total knee arthroplasty (TKA), unicompartmental knee arthroplasty (UKA), high tibial osteotomy (HTO), KineSpring System, and conservative treatments, compared to no treatment, are €2348 ± 70/QALYs, €2040 ± 61/QALYs, €2281 ± 68/ QALY, €1669 ± 268/QALYs, and €11,688 ± 2185/QALYs, respectively. Assuming a treatment durability of 10 years, the cost-utility ratio of TKA, UKA, HTO, KineSpring System, and conservative treatments, compared to no treatment, are €4884 ± 323/QALYs, €4243 ± 280/QALYs, €4744 ± 313/QALYs, €3757 ± 1353/QALYs, and €10,575 ± 4414/QALYs, respectively. In comparison to current standard-of-care treatments, the KineSpring System has a favorable cost-utility ratio, making it an effective treatment option and a suitable cost-saving alternative. The KineSpring System is associated with lower cost and increased QALYs.
authors.affiliation: Global Research Solutions, Inc., Burlington, Ontario, Canada.
authors.forename: Dan
authors.initials: D
authors.lastname: Strain
authors.affiliation: Global Research Solutions, Inc., Burlington, Ontario, Canada; Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Chuan Silvia
authors.initials: CS
authors.lastname: Li
authors.affiliation: Global Research Solutions, Inc., Burlington, Ontario, Canada.
authors.forename: Mark
authors.initials: M
authors.lastname: Phillips
authors.affiliation: Department of Quality Research, Murcia Health Council, Murcia, Spain.
authors.forename: Olga
authors.initials: O
authors.lastname: Monteagudo Piqueras
authors.affiliation: CLARITY Research Group, McMaster University, Department of Orthopedic Surgery Musculoskeletal Research Unit, Canada and Division of Orthopaedic Surgery and Department of Clinical Epidemiology & Biostatistics, Hamilton General Hospital, Canada.
authors.forename: Mohit
authors.initials: M
authors.lastname: Bhandari
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000191:economics; D000072700:Conservative Treatment / Q000191:economics; D003362:Cost-Benefit Analysis; D005260:Female; D062785:Hemiarthroplasty / Q000191:economics; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000191:economics; D020370:Osteoarthritis, Knee / Q000601:surgery*; D010027:Osteotomy / Q000191:economics; D019736:Prostheses and Implants / Q000191:economics*; D019057:Quality-Adjusted Life Years; D013030:Spain; D013977:Tibia / Q000601:surgery