title: Histological findings of divided muscle after peroral endoscopic myotomy.
abstract: Peroral endoscopic myotomy (POEM) is a revolutionary therapy for achalasia and related disorders. POEM utilizes almost the same myotomy procedure as the Heller myotomy; thus, it would be expected to have the same or greater duration of therapeutic effect. However, to date, there have been no reports to prove the basis for this procedure in achalasia. In this case, we were able to histologically show the divided muscle after POEM since the patient had an esophagectomy for esophageal cancer. Histology showed that the muscle tissue divided by the POEM procedure was completely replaced by fibrosis. These findings may indirectly show the permanence of the POEM procedure.
authors.affiliation: Department of Gastroenterological Surgery, Faculty of Medicine, Fukuoka University (Hironari Shiwaku, Kanefumi Yamashita, Toshihiro Ohmiya, Shinsuke Takeno, Takamitsu Sasaki, Yuichi Yamashita).
authors.forename: Hironari
authors.initials: H
authors.lastname: Shiwaku
authors.affiliation: Digestive Disease Center, Showa University Koto Toyosu Hospital, Tokyo (Haruhiro Inoue).
authors.forename: Haruhiro
authors.initials: H
authors.lastname: Inoue
authors.affiliation: Department of Pathology, Faculty of Medicine, Fukuoka University (Satoshi Nimura), Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nimura
authors.affiliation: Department of Gastroenterological Surgery, Faculty of Medicine, Fukuoka University (Hironari Shiwaku, Kanefumi Yamashita, Toshihiro Ohmiya, Shinsuke Takeno, Takamitsu Sasaki, Yuichi Yamashita).
authors.forename: Kanefumi
authors.initials: K
authors.lastname: Yamashita
authors.affiliation: Department of Gastroenterological Surgery, Faculty of Medicine, Fukuoka University (Hironari Shiwaku, Kanefumi Yamashita, Toshihiro Ohmiya, Shinsuke Takeno, Takamitsu Sasaki, Yuichi Yamashita).
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ohmiya
authors.affiliation: Department of Gastroenterological Surgery, Faculty of Medicine, Fukuoka University (Hironari Shiwaku, Kanefumi Yamashita, Toshihiro Ohmiya, Shinsuke Takeno, Takamitsu Sasaki, Yuichi Yamashita).
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Takeno
authors.affiliation: Department of Gastroenterological Surgery, Faculty of Medicine, Fukuoka University (Hironari Shiwaku, Kanefumi Yamashita, Toshihiro Ohmiya, Shinsuke Takeno, Takamitsu Sasaki, Yuichi Yamashita).
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Sasaki
authors.affiliation: Department of Gastroenterological Surgery, Faculty of Medicine, Fukuoka University (Hironari Shiwaku, Kanefumi Yamashita, Toshihiro Ohmiya, Shinsuke Takeno, Takamitsu Sasaki, Yuichi Yamashita).
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Yamashita
keywords: Fibrosis; achalasia; peroral endoscopic myotomy