title: Neurocutaneous Disorders for the Practicing Neurologist: a Focused Review.
abstract: The neurocutaneous disorders (NCDs) embrace an extensive group of developmental disorders associated with involvement of the skin, central nervous system (CNS), and/or the peripheral nervous system (PNS). The neurocutaneous manifestations relate to the common ectodermal origin of these organs. This review intended for the practicing clinical neurologist focuses on selected aspects of the NCDs primarily those associated with cerebrovascular disease. Our emphasis is primarily on those NCDs with genetic heterogeneity and their neurological manifestations.
authors.affiliation: Department of Neurology, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Avenue, Maguire Building, Room 2700, Maywood, IL, 60153, USA.
authors.forename: Anna Carolina Paiva Costa T
authors.initials: AC
authors.lastname: Figueiredo
authors.affiliation: Department of Neurology, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Avenue, Maguire Building, Room 2700, Maywood, IL, 60153, USA.
authors.forename: Nikolas
authors.initials: N
authors.lastname: Mata-Machado
authors.affiliation: Department of Neurology, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Avenue, Maguire Building, Room 2700, Maywood, IL, 60153, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: McCoyd
authors.affiliation: Department of Neurology, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Avenue, Maguire Building, Room 2700, Maywood, IL, 60153, USA. jbiller@lumc.edu.
authors.forename: José
authors.initials: J
authors.lastname: Biller
mesh_terms: D002490:Central Nervous System; D018740:Genetic Heterogeneity; D006801:Humans; D020752:Neurocutaneous Syndromes; D012867:Skin
keywords: Hereditary hemorrhagic telangiectasia; Neurocutaneous disorders; Neurofibromatoses; Pseudoxanthoma elasticum; Tuberous sclerosis complex; Von Hippel-Lindau