title: Ionic strength dependent vesicle adsorption and phase behavior of anionic phospholipids on a gold substrate.
abstract: The authors report on the effect of ionic strength on the formation of supported vesicle layers of anionic phospholipids 1,2-dimyristoyl-sn-glycero-3-phospho-rac-glycerol (DMPG) and dimyristoylphosphatidylserine (DMPS) onto gold. Using quartz crystal microbalance with dissipation monitoring the authors show that vesicle adsorption is mainly governed by NaCl concentration, reflecting the importance of electrostatic interactions in anionic lipids, as compared to zwitterionic 1,2-dimyristoyl-sn-glycero-3-phosphocholine. At low ionic strength, low or no adsorption is observed as a result of vesicle-vesicle electrostatic repulsion. At medium ionic strength, the negative charges of DMPG and DMPS are screened resulting in larger adsorption and a highly dissipative intact vesicle layer. In addition, DMPS exhibits a peculiar behavior at high ionic strength that depends on the temperature of the process.
authors.affiliation: Institute for Materials Research IMO, Hasselt University, Wetenschapspark 1, B-3590 Diepenbeek, Belgium and IMEC, Associated Lab IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium.
authors.forename: Sumit Kumar
authors.initials: SK
authors.lastname: Pramanik
authors.affiliation: Institute for Materials Research IMO, Hasselt University, Wetenschapspark 1, B-3590 Diepenbeek, Belgium and IMEC, Associated Lab IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium.
authors.forename: Senne
authors.initials: S
authors.lastname: Seneca
authors.affiliation: Institute for Materials Research IMO, Hasselt University, Wetenschapspark 1, B-3590 Diepenbeek, Belgium and IMEC, Associated Lab IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium.
authors.forename: Anitha
authors.initials: A
authors.lastname: Ethirajan
authors.affiliation: Institute for Materials Research IMO, Hasselt University, Wetenschapspark 1, B-3590 Diepenbeek, Belgium and IMEC, Associated Lab IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium.
authors.forename: Shova
authors.initials: S
authors.lastname: Neupane
authors.affiliation: Institute for Materials Research IMO, Hasselt University, Wetenschapspark 1, B-3590 Diepenbeek, Belgium and IMEC, Associated Lab IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium.
authors.forename: Frank Uwe
authors.initials: FU
authors.lastname: Renner
authors.affiliation: Institute for Materials Research IMO, Hasselt University, Wetenschapspark 1, B-3590 Diepenbeek, Belgium and IMEC, Associated Lab IMOMEC, Wetenschapspark 1, 3590 Diepenbeek, Belgium.
authors.forename: Patricia
authors.initials: P
authors.lastname: Losada-Pérez
mesh_terms: D000327:Adsorption; D006046:Gold / Q000737:chemistry*; D009994:Osmolar Concentration; D010715:Phosphatidylglycerols / Q000737:chemistry*; D010718:Phosphatidylserines / Q000737:chemistry*; D012965:Sodium Chloride / Q000737:chemistry*; D055672:Static Electricity
chemical_list: D010715:Phosphatidylglycerols; D010718:Phosphatidylserines; D012965:Sodium Chloride; C042859:dimyristoylphosphatidylserine; D006046:Gold; C002773:dimyristoylphosphatidylglycerol