title: More work needed to crack the nut.
abstract: The STOP II study provides high-quality evidence on the efficacy, safety and impact on quality of life of oral immunotherapy (OIT) in peanut-allergic children. Although the results are promising, significant concerns and knowledge gaps remain regarding the safety of OIT, its ability to induce long-term tolerance once regular peanut intake is stopped and, accordingly, long-term adherence. Peanut OIT therefore needs to be restricted to research studies aiming to complete the current evidence gaps.
authors.affiliation: Division of Paediatrics, Faculty of Medicine, Imperial College London, London, W2 1PG, U.K. m.vazquez-ortiz@imperial.ac.uk.
authors.forename: M
authors.initials: M
authors.lastname: Vazquez-Ortiz
mesh_terms: D003888:Desensitization, Immunologic / Q000379:methods*; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D008297:Male; D021183:Peanut Hypersensitivity / Q000276:immunology* / Q000517:prevention & control*