title: Relation between three-dimensional and two-dimensional echocardiography and biochemical analysis in patients with ST-segment elevation myocardial infarction percutaneously treated.
abstract: OBJECTIVE
  The prognosis of patients with acute myocardial infarction depends on multiple features that can demonstrate myocardial injury degree (such as serum markers of cardiac necrosis), and also on adaptive mechanisms relative to the acute event. The aim of the study was to assess the relation between biochemical and echocardiographic findings from three-dimensional echocardiographic (3D Echo) analysis and echocardiographic two-dimensional (2D Echo) left ventricular ejection fraction in patients with ST-segment elevation acute myocardial infarction, submitted to primary percutaneous treatment.
  
  
  METHODS
  A prospective study with 2D Echo and 3D Echo of 23 patients (17 males, mean age of 57 ± 13 years) with ST-segment elevation acute myocardial infarction, primarily percutaneously treated (stent). Serum cardiac markers (creatine kinase MB, Troponin I and Myoglobin) and serum brain natriuretic peptide were compared to echocardiographic parameters (volumes, left ventricular ejection fraction and ventricular dyssynchrony index). The statistical analysis was performed using Pearson's correlation coefficient, 95% CI, p < 0.05, linear regression equation and Bland & Altman test.
  
  
  RESULTS
  Pearson's correlation coefficient (r)relative to 3D left ventricular ejection fraction: 1- brain natriuretic peptide: r: - 0.7427, p < 0.0001; 2- creatine kinase MB: r: - 0.660, p = 0.001. Left ventricular ejection fraction 2D (r) : 1- brain natriuretic peptide: r: - 0.5478, p = 0.001; 2- creatine kinase MB: r: - 0.4800, p < 0.0277. Other associations were not significant.
  
  
  CONCLUSIONS
  In this series, it was observed better correlation in regard to serum creatine kinase MB, brain natriuretic peptide and 3D Echo left ventricular ejection fraction, when compared to 2D Echo left ventricular ejection fraction.
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Marcelo Luiz Campos
authors.initials: ML
authors.lastname: Vieira
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Wercules Antônio
authors.initials: WA
authors.lastname: Oliveira
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Alexandre Ferreira
authors.initials: AF
authors.lastname: Cury
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Adriana
authors.initials: A
authors.lastname: Cordovil
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Ana Clara Tude
authors.initials: AC
authors.lastname: Rodrigues
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Gustavo Alberto Frazatto
authors.initials: GA
authors.lastname: Naccarato
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Claudia Gianini
authors.initials: CG
authors.lastname: Monaco
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Lea Paula Ravani Beneti
authors.initials: LP
authors.lastname: Costa
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Renata Barbara
authors.initials: RB
authors.lastname: Romano
authors.affiliation: Diagnostic Cardiology and Clinical Neurophysiology, Diagnostic and Preventive Medicine, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: João Roberto
authors.initials: JR
authors.lastname: Calatroia
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Tania Regina
authors.initials: TR
authors.lastname: Afonso
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Glaucia Maria Penha
authors.initials: GM
authors.lastname: Tavares
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Laise Antônia Bonfim
authors.initials: LA
authors.lastname: Guimarães
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Edgar Bezerra
authors.initials: EB
authors.lastname: Lira Filho
authors.affiliation: Cardiovascular Intervention, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Marco Antonio
authors.initials: MA
authors.lastname: Perin
authors.affiliation: Department of Echocardiography, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Claudio Henrique
authors.initials: CH
authors.lastname: Fischer
authors.affiliation: Diagnostic Cardiology and Clinical Neurophysiology, Diagnostic and Preventive Medicine, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, Brazil.
authors.forename: Samira Saady
authors.initials: SS
authors.lastname: Morhy