title: Serum lipid profiles, the prevalence of dyslipidemia and the risk factors in two isolated Chinese minorities.
abstract: Both Jing and Mulao nationalities are the isolated minorities in China. Little is known about the prevalence of dyslipidemia between the two ethnic groups. Therefore, the aim of this study was to compare the differences in serum lipid profiles, the prevalence of dyslipidemia and their risk factors between the Jing and Mulao populations. A cross-sectional study of dyslipidemia was conducted in Dongxing city, Guangxi, China, during Dec 2011 and Jan 2012. A total of 1254 subjects of Jing and 1251 participants of Mulao were surveyed by a stratified randomized sampling. Information on demography, diet and lifestyle was collected with standardized questionnaire. Serum lipid levels were detected using the commercially available kits. The levels of low-density lipoprotein cholesterol (LDL-C), apolipoprotein (Apo) A1, and the ratio of ApoA1 to ApoB were lower but the levels of ApoB were higher in Jing than in Mulao (P < 0.001 for all). The prevalence of hypertriglyceridemia (32.38% vs. 24.38%), high ApoB (35.25% vs. 15.35%) and low ApoA1/ApoB ratio (22.65% vs. 16.87%) was higher and low high-density lipoprotein cholesterol (0.48% vs. 2.16%), high LDL-C (17.54% vs. 40.53%) and low ApoA1 (5.98% vs. 11.43%) was lower in Jing than in Mulao (P < 0.001 for all). The risk factors for serum lipid parameters and hyperlipidemia were different between the two ethnic groups. Serum lipid profiles, the prevalence of dyslipidemia and their risk factors are different between the Jing and Mulao populations. These differences may result from the combined effects of different diet, lifestyle, and genetic factors.
authors.affiliation: Department of Cardiology, Institute of Cardiovascular Diseases, The First Affiliated Hospital, Guangxi Medical University Nanning, China.
authors.forename: Pei-Juan
authors.initials: PJ
authors.lastname: Liao
authors.affiliation: Department of Cardiology, Hezhou People's Hospital Hezhou, China.
authors.forename: Rui-Bin
authors.initials: RB
authors.lastname: Xie
authors.affiliation: Department of Cardiology, Institute of Cardiovascular Diseases, The First Affiliated Hospital, Guangxi Medical University Nanning, China.
authors.forename: Rui-Xing
authors.initials: RX
authors.lastname: Yin
authors.affiliation: The Disease Control and Prevention Center Luocheng Mulao Autonomous County, Hechi, China.
authors.forename: Dai-Xun
authors.initials: DX
authors.lastname: Wei
authors.affiliation: Department of General Practice, Jiangping Health Station of Dongxing City Dongxing, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Huang
authors.affiliation: Department of Cardiology, Institute of Cardiovascular Diseases, The First Affiliated Hospital, Guangxi Medical University Nanning, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Huang
authors.affiliation: Clinical Laboratory of The Affiliated Cancer Hospital, Guangxi Medical University Nanning, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Molecular Genetics, Medical Scientific Research Center, Guangxi Medical University Nanning, China.
authors.forename: Wei-Xiong
authors.initials: WX
authors.lastname: Lin
authors.affiliation: Department of Cardiology, Institute of Cardiovascular Diseases, The First Affiliated Hospital, Guangxi Medical University Nanning, China.
authors.forename: Jin-Zhen
authors.initials: JZ
authors.lastname: Wu
authors.affiliation: Department of Pathophysiology, School of Premedical Sciences, Guangxi Medical University Nanning, China.
authors.forename: Shang-Ling
authors.initials: SL
authors.lastname: Pan
keywords: Lipids; apolipoproteins; dyslipidemia; prevalence; risk factors