title: Effects of intraocular lenses with different diopters on chromatic aberrations in human eye models.
abstract: BACKGROUND
  In this study, the effects of intraocular lenses (IOLs) with different diopters (D) on chromatic aberration were investigated in human eye models, and the influences of the central thickness of IOLs on chromatic aberration were compared.
  
  
  METHODS
  A Liou-Brennan-based IOL eye model was constructed using ZEMAX optical design software. Spherical IOLs with different diopters (AR40e, AMO Company, USA) were implanted; modulation transfer function (MTF) values at 3 mm of pupil diameter and from 0 to out-of-focus blur were collected and graphed.
  
  
  RESULTS
  MTF values, measured at 555 nm of monochromatic light under each spatial frequency, were significantly higher than the values measured at 470 to 650 nm of polychromatic light. The influences of chromatic aberration on MTF values decreased with the increase in IOL diopter when the spatial frequency was ≤12 c/d, while increased effects were observed when the spatial frequency was ≥15 c/d. The MTF values of each IOL eye model were significantly lower than the MTF values of the Liou-Brennan eye models when measured at 555 nm of monochromatic light and at 470 to 650 nm of polychromatic light. The MTF values were also found to be increased with the increase in IOL diopter.
  
  
  CONCLUSIONS
  With higher diopters of IOLs, the central thickness increased accordingly, which could have created increased chromatic aberration and decreased the retinal image quality. To improve the postoperative visual quality, IOLs with lower chromatic aberration should be selected for patients with short axial lengths.
authors.affiliation: Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Clinical College of Ophthalmology, Tianjin Medical University, No. 4 Gansu Rd, Heping District, Tianjin, 300020, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Song
authors.affiliation: Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Clinical College of Ophthalmology, Tianjin Medical University, No. 4 Gansu Rd, Heping District, Tianjin, 300020, China.
authors.forename: Xiaoyong
authors.initials: X
authors.lastname: Yuan
authors.affiliation: Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Vision Science, Clinical College of Ophthalmology, Tianjin Medical University, No. 4 Gansu Rd, Heping District, Tianjin, 300020, China. tangprofessor@aliyun.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Tang
mesh_terms: D003198:Computer Simulation; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008954:Models, Biological; D055095:Optics and Photonics; D019591:Pseudophakia / Q000503:physiopathology*; D011680:Pupil / Q000502:physiology; D012029:Refraction, Ocular / Q000502:physiology*; D012030:Refractive Errors / Q000503:physiopathology*