title: [Perioperative Effect of Intraoperative Fluid Restriction with the Same Fixed Volume of 5 ml · kg(-1) · h(-1) in Patients Undergoing Major Abdominal Versus Thoracic Surgery].
abstract: BACKGROUND
  Major abdominal surgery accompanies the higher magnitude of physiological stress response and may require an additional replacement fluid for the redistributed volume. Intraoperative volume restriction strategy is recommended to avoid fluid overload leading to increased mortality. We conducted a comparative study of the perioperative effects of intraoperative fluid restriction in abdominal versus thoracic surgery.
  
  
  METHODS
  Each 15 patients having major abdominal or thoracic surgery were studied prospectively. All participants were identically given intraoperative iv crystalloid of 5 ml · kg(-1) · hr(-1) under combined epidural/general anesthesia. Plasma level of AVP, aldosterone, angiotensin II and IL-6 as well as body water composition by bioelectrical impedance analysis was examined at preoperative period, at the end of surgery and on the first postoperative day.
  
  
  RESULTS
  In abdominal surgery group there was significantly less intraoperative urine output compared with thoracic surgery group. No significant differences were found between two groups in extracellular water volume chnages, AVP, aldosterone angiotensin II, IL-6 level and postoperative renal function.
  
  
  CONCLUSIONS
  Restrictive fluid therapy with intraoperative crystalloid of 5 ml · kg(-1) · hr(-1) can be safely used with no serious adverse events in abdominal surgery. In conclusion we had better not make any traditional difference in intraoperative fluid management between abdominal and thoracic surgery even if their stress response differs in magnitude.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kaida
authors.forename: Masaki
authors.initials: M
authors.lastname: Wakamatsu
authors.forename: Asami
authors.initials: A
authors.lastname: Machino
authors.forename: Hiroko
authors.initials: H
authors.lastname: Hirano
authors.forename: Yasuichiro
authors.initials: Y
authors.lastname: Mori
authors.forename: Saeko
authors.initials: S
authors.lastname: Yamazaki
authors.forename: Shin
authors.initials: S
authors.lastname: Haku
authors.forename: Ai
authors.initials: A
authors.lastname: Takahashi
mesh_terms: D000005:Abdomen / Q000601:surgery*; D000368:Aged; D000077324:Crystalloid Solutions; D005440:Fluid Therapy; D006801:Humans; D007432:Intraoperative Period; D007552:Isotonic Solutions; D008875:Middle Aged; D011446:Prospective Studies; D019616:Thoracic Surgical Procedures
chemical_list: D000077324:Crystalloid Solutions; D007552:Isotonic Solutions