title: [Analysis of posterior lumbar interbody fusion (PLIF) in treating lumbar degenerative disease in elderly patients].
abstract: OBJECTIVE
  To explore the clinical effects of PLIF surgery for elderly patients with lumbar degenerative disease.
  
  
  METHODS
  From March 2010 to May 2013, 28 patients with lumbar degenerative disease, aged more than 80 years were treated with PLIF surgery. There were 10 males and 18 females, aged from 80 to 93 years old with an average of (85.44±3.66) years. Course of disease was from 3 to 20 years. The operation time, intra-operative blood loss, operation complications were recorded and JOA scores and Macnab criteria were used to evaluate the clinical outcomes.
  
  
  RESULTS
  All patients were followed up from 12 to 40 months with an average of 26.5 months. The average operation time was (150.00±26.42) min and the average intra-operative blood loss was (373.33±99.88) ml. The pre-operative JOA score was 12.30±2.43, and the corresponding postoperative JOA score at the final follow-up was 24.81±2.09 which was much higher than the preoperative one (P<0.01). According to the modified Macnab criteria to evaluate at the final follow-up, 16 patients got an excellent result, 10 good, 2 fair. In the weeks postoperatively, injuries of nerve root happened in 3 cases, superficial wound infection with delayed healing in 3 cases, and tear of the dural sac accompanied with cerebrospinal fluid leakage in 1 case. After long term follow-up, adjacent segment degeneration and the corresponding spinal canal stenosis occurred in 1 case at 34 months after operation. All cases got successful fusion without any displacement of internal fixation and pseudoarthrosis formation.
  
  
  CONCLUSIONS
  With proper cases, fully preoperative preparation, perfect intra-operative manipulation and active treatment after operation, even advanced ages older than 80 years with lumbar degenerative disease could get satisfactory outcomes after PLIF surgery.
authors.forename: Yi-chun
authors.initials: YC
authors.lastname: Xu
authors.forename: Hui
authors.initials: H
authors.lastname: Yao
authors.forename: Qi-you
authors.initials: QY
authors.lastname: Wang
authors.forename: Gang
authors.initials: G
authors.lastname: Hou
authors.forename: Hui-qing
authors.initials: HQ
authors.lastname: Zhao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D061646:Operative Time; D013122:Spinal Diseases / Q000601:surgery*; D013123:Spinal Fusion / Q000379:methods*