title: Life in a Diverse Oral Community - Strategies for Oxidative Stress Survival.
abstract: BACKGROUND
  While the oral cavity harbors more than 680 bacterial species, the interaction and association of selected bacterial species play a role in periodontal diseases. Bacterial species includingPorphyromonas gingivalis,Treponema denticolaandTannerella forsythia, a consortium previously designated as the "red complex"is now being expanded to include other new emerging pathogens that are significantly associated with periodontal disease.
  
  
  CONCLUSIONS
  In addition to novel mechanisms for oxidative resistance of individual species, community dynamics may lead to an overall strategy for survival in the inflammatory environment of the periodontal pocket. Complex systems controlled by response regulators protect against oxidative and nitrosative stress.
  
  
  CONCLUSIONS
  The combination of these multifaceted strategies would provide a comprehensive defense and support system against the repetitive host immune response to promote microbial persistence and disease.
authors.affiliation: Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
authors.forename: Leroy G
authors.initials: LG
authors.lastname: Henry
authors.affiliation: Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
authors.forename: Marie-Claire
authors.initials: MC
authors.lastname: Boutrin
authors.affiliation: Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
authors.forename: Wilson
authors.initials: W
authors.lastname: Aruni
authors.affiliation: Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
authors.forename: Antonette
authors.initials: A
authors.lastname: Robles
authors.affiliation: Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
authors.forename: Alexia
authors.initials: A
authors.lastname: Ximinies
authors.affiliation: Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California 92350.
authors.forename: Hansel M
authors.initials: HM
authors.lastname: Fletcher
keywords: Filifactor alocis; Porphyromonas gingivalis; oral microbiome; oxidative stress; red complex