title: [A Case of Anti-GQ1b Antibody Syndrome Associated with Pure Bilateral Adie's Pupils].
abstract: A 37 year-old Japanese male felt photophobia of both eyes one week following the onset of the common cold. His neurological examination revealed bilateral Adie's tonic pupils, no extraocular movement disorder, normal deep tendon reflexes, and no cerebellar signs. Based on markedly increased blood levels of anti-GQ1b IgG and anti-GT1a IgG antibodies, we diagnosed him as anti-GQ1b antibody syndrome. Bilateral Adie's tonic pupils were improved by IVIg drip infusion and methylprednisolone pulse therapy. This case suggests that we need to investigate anti ganglioside antibody when a patient presents with bilateral Adie's tonic pupils.
authors.affiliation: Department of Neurology, Osaka Red Cross Hospital.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Kajikawa
authors.forename: Takekazu
authors.initials: T
authors.lastname: Ohi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Fujita
authors.forename: Susumu
authors.initials: S
authors.lastname: Kusunoki
mesh_terms: D000328:Adult; D000906:Antibodies / Q000276:immunology*; D005123:Eye / Q000276:immunology*; D006801:Humans; D007262:Infusions, Intravenous / Q000379:methods; D008297:Male; D013577:Syndrome; D015845:Tonic Pupil / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*
chemical_list: D000906:Antibodies