title: Hyperuricaemia in patients with type 2 diabetes in a tertiary healthcare centre in sub-Saharan Africa: prevalence and determinants.
abstract: Hyperuricaemia in type 2 diabetes mellitus (T2DM) has been less well investigated in sub-Saharan Africans. Our study of 438 patients found that alcohol intake, body mass index ≥25 kg/m2, hydrochlorothiazide use, statin use, diabetic retinopathy and glomerular filtration rate <60 mL/min/1.73m2were independently positively associated with hyperuricaemia; whereas smoking reduced this risk. Hyperuricaemia is strongly associated with some modifiable factors, diabetic complications and certain drugs. Our results suggest that further studies should evaluate the potential cost-benefit of screening for hyperuricaemia in type 2 diabetes.
authors.affiliation: Associate Professor of Medicine, Health and Human Development (2HD) Research Group, Douala, Cameroon Associate Professor of Medicine, Department of Internal Medicine, Douala General Hospital, Douala, Douala, Cameroon Associate Professor of Medicine, Department of Internal Medicine and Paediatrics, Faculty of Health Sciences, University of Buea, Buea, Cameroon schoukem@gmail.com.
authors.forename: Simeon-Pierre
authors.initials: SP
authors.lastname: Choukem
authors.affiliation: General practitioner, Health and Human Development (2HD) Research Group, Douala, Cameroon General practitioner, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
authors.forename: Juliette-Amelie
authors.initials: JA
authors.lastname: Mengue
authors.affiliation: Associate Professor of Medicine, Department of Internal Medicine, Douala General Hospital, Douala, Douala, Cameroon.
authors.forename: Marie-Solange
authors.initials: MS
authors.lastname: Doualla
authors.affiliation: PhD Student, Laboratory of Molecular Medicine and Metabolism, Biotechnology Centre, Nkolbisson, University of Yaounde, Yaounde, Cameroon.
authors.forename: Olivier-Tresor
authors.initials: OT
authors.lastname: Donfack
authors.affiliation: Associate Professor of Medicine, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
authors.forename: Gerard
authors.initials: G
authors.lastname: Beyiha
authors.affiliation: Associate Professor of Medicine, Department of Internal Medicine, Douala General Hospital, Douala, Douala, Cameroon.
authors.forename: Henry N
authors.initials: HN
authors.lastname: Luma
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D044383:Black People / Q000706:statistics & numerical data; D015992:Body Mass Index; D002163:Cameroon / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology*; D003930:Diabetic Retinopathy / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D033461:Hyperuricemia / Q000097:blood* / Q000150:complications / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D062606:Tertiary Care Centers; D063128:Tertiary Health Care
chemical_list: D015415:Biomarkers
keywords: Cameroon; Hyperuricaemia; determinants; prevalence; type 2 diabetes mellitus