title: Interfacial nano-biosensing in microfluidic droplets for high-sensitivity detection of low-solubility molecules.
abstract: Taking advantage of the properties of the high surface-area-to-volume ratio of microfluidic droplets, we developed an innovative interfacial nanosensing strategy based on aptamer-functionalized graphene oxide nanosensors in microfluidic droplets for the high-sensitivity one-step detection of 17β-estradiol and other low-solubility molecules, with the detection sensitivity improved by about 3 orders of magnitude compared to conventional systems.
authors.affiliation: Department of Chemistry, University of Texas at El Paso, 500 West University Ave., El Paso, Texas 79968, USA.
authors.forename: Maowei
authors.initials: M
authors.lastname: Dou
authors.forename: José Mireles
authors.initials: JM
authors.lastname: García
authors.forename: Sihui
authors.initials: S
authors.lastname: Zhan
authors.forename: XiuJun
authors.initials: X
authors.lastname: Li
mesh_terms: D015374:Biosensing Techniques; D004958:Estradiol / Q000032:analysis; D057230:Limit of Detection; D044085:Microfluidics; D036103:Nanotechnology; D012995:Solubility
chemical_list: D004958:Estradiol