title: Synthetic cannabinoid 3-benzyl-5-[1-(2-pyrrolidin-1-ylethyl)-1H-indol-3-yl]-1,2,4-oxadiazole. The first detection in illicit market of new psychoactive substances.
abstract: We were the first to detect 3-benzyl-5-[1-(2-pyrrolidin-1-ylethyl)-1H-indol-3-yl]-1,2,4-oxadiazole (given name BzODZ-EPyr) as a new synthetic cannabinoid, in illegal market of new psychoactive compounds (NPS). The compound was known only from pharmaceutical literature so far. BzODZ-EPyr was identified by means of gas chromatography/mass spectrometry (GC/MS) including high resolution mass spectrometry (GC/HRMS), ultra-high performance liquid chromatography/high resolution tandem mass spectrometry (UHPLC/HRMS(2)), Fourier-transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance spectroscopy (NMR) (1)H and (13)C. The peculiarities of mass-spectral fragmentation in experiments in electronic ionization (EI) and collision-induced dissociation (CID) modes were studied. Herewith we report analytical characteristics of BzODZ-EPyr enabling its (and possible analogues thereof) determination in criminal seizures.
authors.affiliation: Ural Federal University, Institute of Chemical Technology, 19 Mira Street, 620002 Ekaterinburg, Russian Federation. Electronic address: vadim.shevyrin@gmail.com.
authors.forename: Vadim
authors.initials: V
authors.lastname: Shevyrin
authors.affiliation: Expert and Criminalistic Center, Main Agency of the Ministry of the Interior of the Russian Federation, Sverdlovsk Region Branch, 17 Lenina Avenue, 620014 Ekaterinburg, Russian Federation. Electronic address: experts@ru66.ru.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Melkozerov
authors.affiliation: Ural Federal University, Institute of Chemical Technology, 19 Mira Street, 620002 Ekaterinburg, Russian Federation. Electronic address: oleg-eltsov@yandex.ru.
authors.forename: Oleg
authors.initials: O
authors.lastname: Eltsov
authors.affiliation: Ural Federal University, Institute of Chemical Technology, 19 Mira Street, 620002 Ekaterinburg, Russian Federation. Electronic address: yu.m.shafran@urfu.ru.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Shafran
authors.affiliation: Ural Federal University, Institute of Chemical Technology, 19 Mira Street, 620002 Ekaterinburg, Russian Federation. Electronic address: morzherin@mail.ru.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Morzherin
mesh_terms: D002186:Cannabinoids / Q000032:analysis*; D015198:Designer Drugs / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D013287:Illicit Drugs / Q000032:analysis*; D010069:Oxadiazoles / Q000032:analysis*; D011619:Psychotropic Drugs
chemical_list: D002186:Cannabinoids; D015198:Designer Drugs; D013287:Illicit Drugs; D010069:Oxadiazoles; D011619:Psychotropic Drugs
keywords: Analogues of 3-carbonylindoles; Designer drugs; Identification; Synthetic cannabinoids