title: Sudden cardiac death in asymptomatic aortic stenosis: is the valve to blame?
abstract: An active 68-year-old man with asymptomatic severe aortic stenosis and normal functional capacity on a conventional bicycle exercise test underwent a haemodynamic stress test with simultaneous invasive haemodynamic monitoring and echocardiography during supine bicycle testing as part of a research project. With exercise, the patient developed pulmonary venous hypertension and mild regional wall motion abnormalities on echocardiography. The patient terminated the test due to exhaustion. In the recovery period, he developed sustained ventricular tachycardia and became unconscious. No symptoms were present during exercise or prior to cardiac arrest. The following coronary angiogram revealed significant 2-vessel disease, and the patient subsequently underwent successful aortic valve replacement and coronary-artery bypass graft surgery.
authors.affiliation: University Hospital of Odense, Odense, Denmark.
authors.forename: Nicolaj Lyhne
authors.identifier: http://orcid.org/0000-0002-4895-0588
authors.initials: NL
authors.lastname: Christensen
authors.affiliation: University Hospital of Odense, Odense, Denmark.
authors.forename: Rasmus
authors.initials: R
authors.lastname: Carter-Storch
authors.affiliation: University Hospital of Odense, Odense, Denmark.
authors.forename: Rine
authors.initials: R
authors.lastname: Bakkestrøm
authors.affiliation: Department of Cardiology, University Hospital of Odense, Odense, Denmark.
authors.forename: Jordi Sanchez
authors.initials: JS
authors.lastname: Dahl
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000150:complications* / Q000601:surgery; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D016757:Death, Sudden, Cardiac / Q000209:etiology*; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D005080:Exercise Test; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D016277:Ventricular Function, Left