title: Polyelectrolyte complexes: mechanisms, critical experimental aspects, and applications.
abstract: The polyelectrolyte complexes (PECs) are versatile formulations formed by electrostatic interactions between oppositely charged biopolymers. PECs have been investigated widely by the researchers to explore the virtues of this formulation viz. high biocompatibility, excellent biodegradability, low toxicity, cost-effective, environment-friendly, and energy-efficient production. The prime object of the present review is to present the prominent features of PECs including mechanism of PEC formation, structural models of PECs, interactions involved in PEC formation, steps involved in PEC fabrication, factors affecting the formation of PECs and applications of PECs. The patents pertaining to PECs have briefly been tabulated as well.
authors.affiliation: a Department of Pharmaceutics , R. C. Patel Institute of Pharmaceutical Education and Research , Shirpur , Maharashtra , India ;
authors.forename: Abhijeet D
authors.initials: AD
authors.lastname: Kulkarni
authors.affiliation: a Department of Pharmaceutics , R. C. Patel Institute of Pharmaceutical Education and Research , Shirpur , Maharashtra , India ;
authors.forename: Yogesh H
authors.initials: YH
authors.lastname: Vanjari
authors.affiliation: a Department of Pharmaceutics , R. C. Patel Institute of Pharmaceutical Education and Research , Shirpur , Maharashtra , India ;
authors.forename: Karan H
authors.initials: KH
authors.lastname: Sancheti
authors.affiliation: a Department of Pharmaceutics , R. C. Patel Institute of Pharmaceutical Education and Research , Shirpur , Maharashtra , India ;
authors.forename: Harun M
authors.initials: HM
authors.lastname: Patel
authors.affiliation: b Department of Pharmaceutical Sciences , RTM Nagpur University , Nagpur , Maharashtra , India.
authors.forename: Veena S
authors.initials: VS
authors.lastname: Belgamwar
authors.affiliation: a Department of Pharmaceutics , R. C. Patel Institute of Pharmaceutical Education and Research , Shirpur , Maharashtra , India ;
authors.forename: Sanjay J
authors.initials: SJ
authors.lastname: Surana
authors.affiliation: a Department of Pharmaceutics , R. C. Patel Institute of Pharmaceutical Education and Research , Shirpur , Maharashtra , India ;
authors.forename: Chandrakantsing V
authors.initials: CV
authors.lastname: Pardeshi
mesh_terms: D000071228:Polyelectrolytes / Q000737:chemistry*; D055672:Static Electricity
chemical_list: D000071228:Polyelectrolytes
keywords: Biomedical applications; drug delivery; electrostatic interactions; polyelectrolyte complex; polyions