title: Hepatitis B immune reconstitution syndrome in a patient with HIV infection.
abstract: South Africa has a high rate of HIV and hepatitis B co-infection. The national HIV treatment guidelines include anti-retrovirals that treat both viruses. We describe a HIV-positive patient who presented with liver histology-confirmed hepatitis B immune reconstitution inflammatory syndrome whilst on a regimen containing lamivudine and tenofovir.
authors.affiliation: Department of Infectious Diseases, UKZN, South Africa Enhancing Care Foundation, South Africa petrea.place@gmail.com.
authors.forename: Melanie-Anne A
authors.initials: MA
authors.lastname: John
authors.affiliation: Department of Infectious Diseases, UKZN, South Africa Department of Infectious Disease, King Edward VIII Hospital, UKZN, South Africa.
authors.forename: Bernadett I
authors.initials: BI
authors.lastname: Gosnell
authors.affiliation: Department of Infectious Diseases, UKZN, South Africa Department of Infectious Disease, King Edward VIII Hospital, UKZN, South Africa.
authors.forename: Thandekile C
authors.initials: TC
authors.lastname: Manzini
authors.affiliation: Department of Anatomical Pathology, Inkosi Albert Luthuli Hospital, National Health Laboratory Services, South Africa.
authors.forename: Prastistadevi
authors.initials: P
authors.lastname: Ramdial
authors.affiliation: Department of Infectious Diseases, UKZN, South Africa Department of Infectious Disease, King Edward VIII Hospital, UKZN, South Africa.
authors.forename: Mahomed-Yunus S
authors.initials: MS
authors.lastname: Moosa
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D060085:Coinfection / Q000821:virology; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000821:virology; D015497:HIV-1 / Q000187:drug effects; D006509:Hepatitis B / Q000150:complications* / Q000188:drug therapy / Q000821:virology; D006515:Hepatitis B virus / Q000187:drug effects / Q000235:genetics; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000150:complications* / Q000188:drug therapy; D019259:Lamivudine / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D019380:Anti-HIV Agents; D019259:Lamivudine
keywords: AIDS; HIV; co-infection; hepatitis B virus; immune reconstitution inflammatory syndrome