title: Synchronous bilateral primary breast malignant phyllodes tumor and carcinoma of the breast with Paget's disease: a case report and review of the literature.
abstract: Synchronous bilateral primary breast malignant phyllodes tumor or/and carcinoma of the breast with Paget's disease is rare. In the article, we present a case of bilateral carcinoma of the breast with Paget's disease of the right breast and malignant phyllodes tumor of the left breast. A 44-years-old Chinese woman presented with a 1 month history of the right breast nipple with eczema and fester and growing and palpable mass of left breast. Molybdenum target X-ray revealed microcalcification in the right breast, which was highly suspected of malignant tumor, and round-like mass with smooth surface and homogeneous density in the left breast. Color ultrasound showed a lobulated lump which circumferential blood flows around in the left breast, and which did not show any mass in the right breast. The patient was undertaken the bilateral modified radical mastectomy. The histological diagnosis was Paget's disease associated with infiltrating ductal carcinoma in the right breast and malignant phyllodes tumor the left breast. The patient also received 6 cycles of the postoperative adjuvant chemotherapy by using T.T. regimen comprised docetaxel (100 mg) and pirarubicin (60 mg).
authors.affiliation: Department of Thyroid & Breast Surgery, Affiliated Hospital, Zunyi Medical College Dalian Rd. 149, Zunyi 563003, China.
authors.forename: Hongyuan
authors.initials: H
authors.lastname: Zhao
authors.affiliation: Department of Thyroid & Breast Surgery, Affiliated Hospital, Zunyi Medical College Dalian Rd. 149, Zunyi 563003, China.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Cheng
authors.affiliation: Department of Thyroid & Breast Surgery, Affiliated Hospital, Zunyi Medical College Dalian Rd. 149, Zunyi 563003, China.
authors.forename: Suhong
authors.initials: S
authors.lastname: Sun
authors.affiliation: Department of Thyroid & Breast Surgery, Affiliated Hospital, Zunyi Medical College Dalian Rd. 149, Zunyi 563003, China.
authors.forename: Weiming
authors.initials: W
authors.lastname: Yang
authors.affiliation: Department of Thyroid & Breast Surgery, Affiliated Hospital, Zunyi Medical College Dalian Rd. 149, Zunyi 563003, China.
authors.forename: Fanli
authors.initials: F
authors.lastname: Kong
authors.affiliation: Department of Thyroid & Breast Surgery, Affiliated Hospital, Zunyi Medical College Dalian Rd. 149, Zunyi 563003, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zeng
keywords: Breast cancer; Paget’s disease; malignant phyllodes tumor