title: To evaluate the biocompatibility of the Indian Portland cement with potential for use in dentistry: An animal study.
abstract: OBJECTIVE
  This study evaluated the biocompatibility of the Indian Portland cement with potential for use in dentistry.
  
  
  METHODS
  This study was performed in Swiss albino mice, by implanting the Indian Portland cement pellets subcutaneously. After 1, 3, and 6 weeks the tissue specimens were prepared for histological examination.
  
  
  RESULTS
  The histological analysis showed moderate to severe inflammation at 1 week. The inflammation gradually decreased by 6 weeks, with most of the specimens showing the absence of inflammatory reaction.
  
  
  CONCLUSIONS
  According to these experimental conditions, the tested Indian Portland cement was biocompatible.
authors.affiliation: Department of Conservative Dentistry and Endodontics, KLE Society's Institute of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
authors.forename: M G
authors.initials: MG
authors.lastname: Mangala
authors.affiliation: Department of Conservative Dentistry and Endodontics, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
authors.forename: S M Sharath
authors.initials: SM
authors.lastname: Chandra
authors.affiliation: Department of Oral Pathology, Krishnadevaraya College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
authors.forename: Radhika M
authors.initials: RM
authors.lastname: Bhavle
keywords: Biocompatibility; Portland cement; inflammation; mice