title: Copper-Catalyzed Denitrogenative Transannulation Reaction of Pyridotriazoles: Synthesis of Imidazo[1,5-a]pyridines with Amines and Amino Acids.
abstract: The copper-catalyzed aerobic oxidative synthesis of imidazo[1,5-a]pyridines via cascade denitrogenative transannulation reaction of pyridotriazoles with benzylamines with good functional group tolerance is developed. The present methodology is also applicable to amino acids to obtain imidazo[1,5-a]pyridines via decarboxylative oxidative cyclization.
authors.affiliation: Academy of Scientific & Innovative Research, CSIR-Central Salt & Marine Chemicals Research Institute, G. B. Marg, Bhavnagar-364 002, Gujarat, India.
authors.forename: Abhisek
authors.initials: A
authors.lastname: Joshi
authors.affiliation: Academy of Scientific & Innovative Research, CSIR-Central Salt & Marine Chemicals Research Institute, G. B. Marg, Bhavnagar-364 002, Gujarat, India.
authors.forename: Darapaneni Chandra
authors.initials: DC
authors.lastname: Mohan
authors.affiliation: Academy of Scientific & Innovative Research, CSIR-Central Salt & Marine Chemicals Research Institute, G. B. Marg, Bhavnagar-364 002, Gujarat, India.
authors.forename: Subbarayappa
authors.initials: S
authors.lastname: Adimurthy
mesh_terms: D000588:Amines / Q000737:chemistry*; D000596:Amino Acids / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D014230:Triazoles / Q000737:chemistry*
chemical_list: D000588:Amines; D000596:Amino Acids; D007093:Imidazoles; D011725:Pyridines; D014230:Triazoles; D003300:Copper