title: Optimization of solid lipid nanoparticles prepared by a single emulsification-solvent evaporation method.
abstract: This data article contains the data related to the research article "Characterization, biorecognitive activity and stability of WGA grafted lipid nanostructures for the controlled delivery of rifampicin" (Pooja et al. 2015) [1]. In the present study, SLN were prepared by a single emulsification-solvent evaporation method and the various steps of SLN preparation are shown in a flow chart. The preparation of SLN was optimized for various formulation variables including type and quantity of lipid, surfactant, amount of co-surfactant and volume of organic phase. Similarly, effect of variables related to homogezation, sonication and stirring processes, on the size and surface potential of SLN was determined and optimized.
authors.affiliation: Medicinal Chemistry & Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
authors.forename: Deep
authors.initials: D
authors.lastname: Pooja
authors.affiliation: Medicinal Chemistry & Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Tunki
authors.affiliation: Medicinal Chemistry & Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India; IICT-RMIT Joint Research Centre, CSIR-Indian Institute of Chemical Technology, Hyderabad, India; Health Innovations Research Institute, RMIT University, Melbourne, Australia.
authors.forename: Hitesh
authors.initials: H
authors.lastname: Kulhari
authors.affiliation: Medicinal Chemistry & Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
authors.forename: Bharathi B
authors.initials: BB
authors.lastname: Reddy
authors.affiliation: Medicinal Chemistry & Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India.
authors.forename: Ramakrishna
authors.initials: R
authors.lastname: Sistla
keywords: Formulation parameters; Optimization; Process variables; Single emulsification-solvent evaporation; Solid lipid nanoparticles