title: High-Resolution Optical Coherence Tomography Findings of Lisch Epithelial Corneal Dystrophy.
abstract: OBJECTIVE
  To describe a case of Lisch epithelial corneal dystrophy (LECD) and present its unique characteristics on high-resolution optical coherence tomography (HR-OCT).
  
  
  METHODS
  A 78-year-old man with whorled corneal epithelial opacities in the right eye was referred for the evaluation of ocular surface squamous neoplasia. Clinical evaluation, photographs, and HR-OCT images of the cornea involved were obtained and scrapings of the affected cornea were sent for histopathologic analysis.
  
  
  RESULTS
  Clinically, the patient presented with an opalescent whirling epithelium in a linear pattern encroaching on the visual axis. HR-OCT showed normal thickness epithelial hyperreflectivity of involved cornea without stromal involvement, along with sharply demarcated borders of unaffected tissue. Histopathologic findings demonstrated vacuolated periodic acid-Schiff (PAS) positive cells throughout the epithelial layers consistent with LECD.
  
  
  CONCLUSIONS
  HR-OCT was able to provide useful information to rule out ocular surface squamous neoplasia and confirm the clinical impression of LECD at the time of clinical examination. HR-OCT shows promise as an adjunctive diagnostic tool for ocular surface lesions and pathologies.
authors.affiliation: *Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL; †Department of Ophthalmology, Miami Veteran Affairs Medical Center, Miami, FL; and ‡Florida Lions Ocular Pathology Laboratory, Miami, FL.
authors.forename: Cameron
authors.initials: C
authors.lastname: Pole
authors.forename: Adam
authors.initials: A
authors.lastname: Sise
authors.forename: Madhura
authors.initials: M
authors.lastname: Joag
authors.forename: Anat
authors.initials: A
authors.lastname: Galor
authors.forename: Jose A
authors.initials: JA
authors.lastname: Bermudez-Magner
authors.forename: Sander
authors.initials: S
authors.lastname: Dubovy
authors.forename: Carol L
authors.initials: CL
authors.lastname: Karp
mesh_terms: D000368:Aged; D003317:Corneal Dystrophies, Hereditary / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D041623:Tomography, Optical Coherence / Q000379:methods*