title: Stress Computed Tomography Myocardial Perfusion Imaging: A New Topic in Cardiology.
abstract: Since its introduction about 15 years ago, coronary computed tomography angiography has become today the most accurate clinical instrument for noninvasive assessment of coronary atherosclerosis. Important technical developments have led to a continuous stream of new clinical applications together with a significant reduction in radiation dose exposure. Latest generation computed tomography scanners (≥ 64 slices) allow the possibility of performing static or dynamic perfusion imaging during stress by using coronary vasodilator agents (adenosine, dipyridamole, or regadenoson), combining both functional and anatomical information in the same examination. In this article, the emerging role and state-of-the-art of myocardial computed tomography perfusion imaging are reviewed and are illustrated by clinical cases from our experience with a second-generation dual-source 128-slice scanner (Somatom Definition Flash, Siemens; Erlangen, Germany). Technical aspects, data analysis, diagnostic accuracy, radiation dose and future prospects are reviewed.
authors.affiliation: Department of Radiology, Interventional Radiology, IRCCS San Martino University Hospital-IST, National Institute for Cancer Research, Genoa, Italy. Electronic address: saraseitun@yahoo.com.
authors.forename: Sara
authors.initials: S
authors.lastname: Seitun
authors.affiliation: Department of Radiology, Interventional Radiology, IRCCS San Martino University Hospital-IST, National Institute for Cancer Research, Genoa, Italy.
authors.forename: Margherita
authors.initials: M
authors.lastname: Castiglione Morelli
authors.affiliation: Department of Radiology, Interventional Radiology, IRCCS San Martino University Hospital-IST, National Institute for Cancer Research, Genoa, Italy.
authors.forename: Irilda
authors.initials: I
authors.lastname: Budaj
authors.affiliation: Department of Radiology, Interventional Radiology, IRCCS San Martino University Hospital-IST, National Institute for Cancer Research, Genoa, Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Boccalini
authors.affiliation: Department of Radiology, Interventional Radiology, IRCCS San Martino University Hospital-IST, National Institute for Cancer Research, Genoa, Italy.
authors.forename: Athena
authors.initials: A
authors.lastname: Galletto Pregliasco
authors.affiliation: Department of Cardiology, IRCCS San Martino University Hospital-IST, National Institute for Cancer Research, Genoa, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Valbusa
authors.affiliation: Department of Radiology, Cardiology, Erasmus Medical Center University, Rotterdam, The Netherlands.
authors.forename: Filippo
authors.initials: F
authors.lastname: Cademartiri
authors.affiliation: Department of Radiology, Interventional Radiology, IRCCS San Martino University Hospital-IST, National Institute for Cancer Research, Genoa, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Ferro
mesh_terms: D000072226:Computed Tomography Angiography / Q000379:methods / Q000592:standards; D005080:Exercise Test / Q000379:methods; D005544:Forecasting; D006801:Humans; D064847:Multimodal Imaging / Q000379:methods; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging*; D055414:Myocardial Perfusion Imaging / Q000379:methods* / Q000592:standards; D010808:Physical Examination / Q000379:methods; D012680:Sensitivity and Specificity
keywords: Computed tomography myocardial perfusion; Dual-energy computed tomography; Imágenes de perfusión miocárdica; Myocardial perfusion imaging; Perfusión miocárdica con tomografía computarizada; Stress computed tomography; Tomografía computarizada de energía dual; Tomografía computarizada de estrés