title: A rare case of Behçet disease with generalised myositis, cardiomyositis and necrotising fasciitis.
abstract: Behçet disease (BD) is a rare relapsing, multisystem vasculitis characterised by recurrent oral and genital ulcers, and uveitis. As an autoimmune small vessel vasculitis, BD can involve other organs including the skin, joints, nervous system, kidney and the gastrointestinal tract. This report describes a 40-year-old woman who presented with an uncommon feature of BD, namely myositis, and who went on to develop myocarditis and polymicrobial necrotising fasciitis. To the best of our knowledge, this is the first reported case of an immunocompromised-associated infection occurring in BD without concurrent immunosuppressive therapy.
authors.affiliation: Department of Neurology, Eastern Health, Melbourne, Victoria, Australia.
authors.forename: Felix
authors.initials: F
authors.lastname: Ng
authors.affiliation: Department of Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia.
authors.forename: Fabian Joon Kiong
authors.initials: FJ
authors.lastname: Chiong
authors.affiliation: Department of Rheumatology, Austin Health, Melbourne, Victoria, Australia.
authors.forename: Russell
authors.initials: R
authors.lastname: Buchanan
authors.affiliation: Department of Medicine, University of Melbourne, Heidleberg, Victoria, Australia.
authors.forename: Louise M
authors.initials: LM
authors.lastname: Burrell
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D019115:Fasciitis, Necrotizing / Q000473:pathology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D009205:Myocarditis / Q000209:etiology*; D009220:Myositis / Q000209:etiology*
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D001379:Azathioprine