title: Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing.
abstract: Wound dressings play an important role in a patient's recovery from health problems, as unattended wounds could lead to serious complications such as infections or, ultimately, even death. Therefore, wound dressings since ancient times have been continuously developed, starting from simple dressings from natural materials for covering wounds to modern dressings with functionalized materials to aid in the wound healing process and enhance tissue repair. However, understanding the nature of a wound and the subsequent healing process is vital information upon which dressings can be tailored to ensure a patient's recovery. To date, much progress has been made through the use of nanomedicine in wound healing due to the ability of such materials to mimic the natural dimensions of tissue. This review provides an overview of recent studies on the physiology of wound healing and various wound dressing materials made of nanofibers fabricated using the electrospinning technique.
authors.affiliation: Materials Science & Technology Program, College of Arts & Sciences, Qatar University, Doha 2713, Qatar.
authors.forename: Alaa J
authors.initials: AJ
authors.lastname: Hassiba
authors.affiliation: Biomedical Research Center, Qatar University, Doha 2713, Qatar.
authors.forename: Mohamed E
authors.initials: ME
authors.lastname: El Zowalaty
authors.affiliation: Biomedical Research Center, Qatar University, Doha 2713, Qatar.|Department of Health Sciences, College of Arts & Sciences, Qatar University, Doha 2713, Qatar.
authors.forename: Gheyath K
authors.initials: GK
authors.lastname: Nasrallah
authors.affiliation: Department of Chemical Engineering & Department of Bioengineering, Northeastern University, Boston, MA 02115, USA.|Center of Excellence for Advanced Material Research, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Webster
authors.affiliation: Center for Advanced Materials, Qatar University, Doha 2713, Qatar.
authors.forename: Adriaan S
authors.initials: AS
authors.lastname: Luyt
authors.affiliation: Center for Advanced Materials, Qatar University, Doha 2713, Qatar.
authors.forename: Aboubakr M
authors.initials: AM
authors.lastname: Abdullah
authors.affiliation: Materials Science & Technology Program, College of Arts & Sciences, Qatar University, Doha 2713, Qatar.
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Elzatahry
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage; D001458:Bandages / Q000382:microbiology; D003692:Delayed-Action Preparations / Q000737:chemistry*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage; D008670:Metals / Q000008:administration & dosage; D057139:Nanofibers / Q000737:chemistry* / Q000648:ultrastructure; D050997:Nanomedicine; D010087:Oxides / Q000008:administration & dosage; D011108:Polymers / Q000737:chemistry*; D014815:Vitamins / Q000008:administration & dosage; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D003692:Delayed-Action Preparations; D036341:Intercellular Signaling Peptides and Proteins; D008670:Metals; D010087:Oxides; D011108:Polymers; D014815:Vitamins
keywords: activity; antimicrobial; biomedical; electrospinning; nanofibers; nanomaterials; wound dressings