title: [Expression of Na(+)/Ca(2+) exchanger channel protein in human odontoblasts and nervous tissue of dental pulp].
abstract: OBJECTIVE
  To investigate the expression of Na(+)/Ca(2+) exchanger 1 (NCX1) channel protein in human odontoblasts (OD) and nervous tissue of dental pulp.
  
  
  METHODS
  Twenty intact and healthy third molars extracted for orthodontic purpose were collected. The OD layer and nervous tissue were determined by dentin sialophosphoproteins (DSPP) antibody staining and modified Bielschowsky silver staining respectivelly. The immunohistochemical method was used to detect the expressions of NCX1 protein in human dental pulp tissue. The difference of expression of NCX1 in human OD at different part of dental pulp was statistically analyzed using Image Pro Plus and SPSS software.
  
  
  RESULTS
  NCX1 channel protein was mainly expressed on the cell body of OD, and nervous tissue of dental pulp. The expression level of NCX1 on the OD of crown pulp was higher (A = 0.146 ± 0.021) than that on the upper part of root pulp (A = 0.120 ± 0.034), but the expression difference was not significant (P > 0.05).
  
  
  CONCLUSIONS
  NCX1 channel protein was expressed on human OD and nervous tissue in dental pulp.
authors.affiliation: Department of Prosthodontics, Stomatological Hospital, Tianjin Medical University, Tianjin 300070, China.
authors.forename: Chengcheng
authors.initials: C
authors.lastname: Zang
authors.forename: Zhiying
authors.initials: Z
authors.lastname: Zhao
authors.forename: Zhen
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Department of Endodontology, Stomatological Hospital, Tianjin Medical University, Tianjin 300070, China; Email: denthua@ 126.com.
authors.forename: Kehua
authors.initials: K
authors.lastname: Que
mesh_terms: D003782:Dental Pulp / Q000294:innervation / Q000378:metabolism*; D003804:Dentin / Q000737:chemistry; D006801:Humans; D008963:Molar; D009804:Odontoblasts / Q000378:metabolism*; D019831:Sodium-Calcium Exchanger / Q000378:metabolism*; D019228:Tooth Crown
chemical_list: D019831:Sodium-Calcium Exchanger; C110374:sodium-calcium exchanger 1