title: Praxis-induced seizures in a patient with juvenile myoclonic epilepsy: MEG-EEG coregistration study.
abstract: OBJECTIVE
  Juvenile myoclonic epilepsy (JME) is one of the most common generalized idiopathic epilepsies of childhood and adolescence. In some patients with JME, mathematical calculus and praxis may induce myoclonic seizures.
  
  
  METHODS
  A reflex myoclonic seizure was recorded by simultaneous magnetoencephalography (MEG) and electroencephalography (EEG) when a generalized spike-wave synchronous pattern at 3 Hz was observed.
  
  
  RESULTS
  Source reconstruction localized the epileptogenic area to the right premotor frontal cortex.
  
  
  CONCLUSIONS
  The present study demonstrates that the origin of epileptiform activity in JME can be localized in brain areas associated with the premotor frontal cortex.
authors.affiliation: Department of Neurology, Teaching General Hospital, Ciudad Real, Spain.
authors.forename: Sira Carrasco-García
authors.initials: SC
authors.lastname: de León
authors.affiliation: Center for Biomedical Technology, Technical University of Madrid, Madrid, Spain; McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montreal, Canada.
authors.forename: Guiomar
authors.initials: G
authors.lastname: Niso
authors.affiliation: Center for Biomedical Technology, Technical University of Madrid, Madrid, Spain.
authors.forename: Leonidas
authors.initials: L
authors.lastname: Canuet
authors.affiliation: Department of Neuropsychology, Teaching General Hospital, Ciudad Real, Spain.
authors.forename: Laura
authors.initials: L
authors.lastname: Burriel-Lobo
authors.affiliation: Center for Biomedical Technology, Technical University of Madrid, Madrid, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Maestú
authors.affiliation: Department of Neurology, Teaching General Hospital, Ciudad Real, Spain.
authors.forename: María Gudín
authors.initials: MG
authors.lastname: Rodríguez-Magariños
keywords: Frontal lobe; Juvenile myoclonic epilepsy; Magnetoencephalography; Praxis-induced seizures; Reflex seizures