title: Serum soluble urokinase-type plasminogen activator receptor levels in male patients with acute exacerbation of schizophrenia.
abstract: Inflammatory abnormalities have been shown in the pathogenesis of schizophrenia. Soluble urokinase-type plasminogen activator receptor (suPAR) is a protein that is measurable in the circulating blood and reflects the inflammation in the body. We aimed to investigate serum suPAR levels in patients with schizophrenia who were in acute state and to compare with healthy controls. Forty five patients and 43 healthy controls were included in the study. We found no significant difference in suPAR levels between patients and controls, suggesting that suPAR as an inflammatory marker does not have a role in the inflammatory process of acute schizophrenia.
authors.affiliation: Departments of Psychiatry, Şişli Etfal Training and Education Hospital, Halaskargazi Avenue, Etfal Street, 34371 Istanbul Turkey. Electronic address: Abdullahgenc@mail.com.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Genc
authors.affiliation: Department of Psychiatry, Bakırkoy Research and Training Hospital for Neurology and Mental, Istanbul, Turkey.
authors.forename: Tevfik
authors.initials: T
authors.lastname: Kalelioglu
authors.affiliation: Department of Psychiatry, Bakırkoy Research and Training Hospital for Neurology and Mental, Istanbul, Turkey.
authors.forename: Nesrin
authors.initials: N
authors.lastname: Karamustafalioglu
authors.affiliation: Department of Psychiatry, Bakırkoy Research and Training Hospital for Neurology and Mental, Istanbul, Turkey.
authors.forename: Akif
authors.initials: A
authors.lastname: Tasdemir
authors.affiliation: Department of Psychiatry, Bakırkoy Research and Training Hospital for Neurology and Mental, Istanbul, Turkey.
authors.forename: Esra Sena
authors.initials: ES
authors.lastname: Genc
authors.affiliation: Department of Psychiatry, Bakırkoy Research and Training Hospital for Neurology and Mental, Istanbul, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Akkus
authors.affiliation: Departments of Psychiatry, Medical School of Cerrahpasa, Istanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Emul
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D018450:Disease Progression; D006801:Humans; D007249:Inflammation / Q000097:blood; D008297:Male; D055293:Receptors, Urokinase Plasminogen Activator / Q000097:blood*; D012559:Schizophrenia / Q000097:blood* / Q000473:pathology
chemical_list: D015415:Biomarkers; D055293:Receptors, Urokinase Plasminogen Activator
keywords: Inflammation; Schizophrenia; Soluble urokinase-type plasminogen activator receptor