title: Silaborative Carbocyclizations of 1,7-Enynes. Diastereoselective Preparation of Chromane Derivatives.
abstract: Palladium(0)-catalyzed carbocyclization of 1,7-enynes mediated by (chlorodimethylsilyl)pinacolborane proceeds with 1,8-addition of the silicon and boron functions to give functionalized cyclohexane derivatives with boron attached to the exocyclic olefin. A variety of chromane dervatives are accessible by this method. In contrast to the analogous reactions with 1,6-enynes, the configuration of the newly formed stereogenic center is controlled by a stereogenic center present in the substrate.
authors.affiliation: KTH Royal Institute of Technology , Department of Chemistry, Organic Chemistry, SE 10044 Stockholm, Sweden.
authors.forename: You-Cai
authors.initials: YC
authors.lastname: Xiao
authors.affiliation: KTH Royal Institute of Technology , Department of Chemistry, Organic Chemistry, SE 10044 Stockholm, Sweden.
authors.forename: Christina
authors.initials: C
authors.lastname: Moberg