title: Hyperpharmacotherapy in ageing cystic fibrosis patients: The first report of an atypical hip fracture.
abstract: Cystic fibrosis (CF) is a common autosomal recessive disorder in Caucasian populations with respiratory, gastrointestinal and endocrine manifestations. Thanks to recent advances in medical therapies and infection control, life expectancy of a patient with CF has significantly increased from less than 5 years in the mid-1900s to almost 50 years nowadays. However, as CF patients are living longer, multimorbidity and Hyperpharmacotherapy are becoming more common. This case illustrates a cascade of problems that ensued from medication side-effects, highlighting the increasing challenge of managing an ageing CF population.
authors.affiliation: All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough, Cardiff, CF64 2XX, United Kingdom.
authors.forename: W A K
authors.initials: WA
authors.lastname: Al-Azzani
authors.affiliation: All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough, Cardiff, CF64 2XX, United Kingdom.
authors.forename: L
authors.initials: L
authors.lastname: Evans
authors.affiliation: All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough, Cardiff, CF64 2XX, United Kingdom.
authors.forename: L
authors.initials: L
authors.lastname: Speight
authors.affiliation: All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough, Cardiff, CF64 2XX, United Kingdom.
authors.forename: M
authors.initials: M
authors.lastname: Lea-Davies
authors.affiliation: Bone Unit, University Hospital Llandough, Cardiff, CF64 2XX, United Kingdom.
authors.forename: M D
authors.initials: MD
authors.lastname: Stone
authors.affiliation: All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough, Cardiff, CF64 2XX, United Kingdom.
authors.forename: D
authors.initials: D
authors.lastname: Lau
authors.affiliation: All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough, Cardiff, CF64 2XX, United Kingdom.
authors.forename: R I
authors.initials: RI
authors.lastname: Ketchell
authors.affiliation: All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough, Cardiff, CF64 2XX, United Kingdom.
authors.forename: J
authors.initials: J
authors.lastname: Duckers
keywords: Bisphosphonate; Bone mineral density; Fracture; Multimorbidity