title: Calcified Pulmonary Nodules Identified in a 350-Year-Old-Joseon Mummy: the First Report on Ancient Pulmonary Tuberculosis from Archaeologically Obtained Pre-modern Korean Samples.
abstract: We found calcified pulmonary nodules in a middle-aged female mummy discovered from 350-yr-old Joseon tomb of Korea. In the CT scan, we found six radiopaque nodules in right lung, through the levels of thoracic vertebrae 1 to 6. We also found presumptive pleural adhesions in right thoracic cavity of CT images. We re-confirmed radiological findings by our post-factum dissection on the same mummy. By the differential diagnosis, we speculate that the radiopaque calcification nodules and associated pleural adhesion could have been caused by tuberculosis. This is the first-ever report on the pulmonary tuberculosis identified in archaeologically obtained, pre-modern Korean samples.
authors.affiliation: Department of Anatomy, Ewha Womans University School of Medicine, Seoul, Korea.
authors.forename: Yi-Suk
authors.identifier: 0000-0002-2865-3957
authors.initials: YS
authors.lastname: Kim
authors.affiliation: Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: In Sun
authors.identifier: 0000-0003-2532-0492
authors.initials: IS
authors.lastname: Lee
authors.affiliation: Bioanthropology and Paleopathology Laboratory, Department of Anatomy/Institute of Forensic Science, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Chang Seok
authors.identifier: 0000-0001-6913-1832
authors.initials: CS
authors.lastname: Oh
authors.affiliation: Department of Anatomy, Dankook University College of Medicine, Chonan, Korea.
authors.forename: Myeung Ju
authors.identifier: 0000-0002-7455-5450
authors.initials: MJ
authors.lastname: Kim
authors.affiliation: Dongguk Institute of Cultural Properties, Daegu, Korea.
authors.forename: Soon Chul
authors.identifier: 0000-0002-3066-0048
authors.initials: SC
authors.lastname: Cha
authors.affiliation: Bioanthropology and Paleopathology Laboratory, Department of Anatomy/Institute of Forensic Science, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Dong Hoon
authors.identifier: 0000-0001-8032-1266
authors.initials: DH
authors.lastname: Shin
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009106:Mummies / Q000000981:diagnostic imaging*; D056910:Republic of Korea; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis*
keywords: Calcified Nodules; Joseon Dynasty; Korean Mummy; Lung; Mycobacterium tuberculosis