title: [Dynamic Changes of Nucleosides and Nucleobases in Different Harvest Periods of Polygoni Multiflori Radix by UPLC-QTRAP-MS/MS].
abstract: OBJECTIVE
  To analyze the dynamic changes of nucleosides and nucleobases in Polygoni Multiflori Radix harvested in different periods.
  
  
  METHODS
  UPLC-QTRAP-MS/MS method was applied for the analysis of nine kinds of nucleosides and nucleobases in Polygoni Multiflori Radix.
  
  
  RESULTS
  The content of uridine, adenine, guanosine and cytidine was higher in Polygoni Multiflori Radix harvested in different periods and assumed some difference. The trends of nucleosides and nucleobases from Polygoni Multiflori Radix according to the peak valley shape changed. The highest contents of them were in December.
  
  
  CONCLUSIONS
  The accumulation of nucleosides and nucleobases in Polygoni Multiflori Radix is closely related to its growth cycle. It is found to be basically the same as that obtained when the herb is collected during the conventional collecting time.
authors.forename: Yi-Yuan
authors.initials: YY
authors.lastname: Luo
authors.forename: Juan-xiu
authors.initials: JX
authors.lastname: Liu
authors.forename: Xun-hong
authors.initials: XH
authors.lastname: Liu
authors.forename: Cai-wu
authors.initials: CW
authors.lastname: Lan
authors.forename: Ya
authors.initials: Y
authors.lastname: Hou
authors.forename: Yang
authors.initials: Y
authors.lastname: Ma
authors.forename: Li
authors.initials: L
authors.lastname: Xu
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal; D009705:Nucleosides / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D028502:Polygonum / Q000737:chemistry*; D053719:Tandem Mass Spectrometry
chemical_list: D004365:Drugs, Chinese Herbal; D009705:Nucleosides