title: Livedoid vasculopathy: fast involution after anticoagulant and hyperbaric oxygen therapy.
abstract: The livedoid vasculopathy is a rare condition characterized by the presence of recurrent painful ulcers in distal extremities of lower limbs. Histologically there is thickness of dermal vessels, occlusion of its light by fibrin thrombi associated with minimal inflammatory infiltrate. It might occur as an isolated condition or be associated with an underlying systemic disease, including coagulation and collagen disorders, or neoplasms. Because it is a rare disease there is no consensus for its treatment. We report a case of a 41-year-old man with painful ulcers in the lower extremities. We did not find any associated diseases. The lesions improved dramatically after treatment with anticoagulant and hyperbaric therapy. We concluded that anticoagulation associated with hyperbaric oxygenation may be benefit for the treatment of patients with livedoid vasculopathy. However, further studies should be done with a larger population to confirm our results.
authors.affiliation: Hematology and Bone Marrow Transplantation, Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
authors.forename: Patricia Weinschenker
authors.initials: PW
authors.lastname: Bollmann
authors.affiliation: Faculdade de Medicina do ABC - FMABC, Santo André, SP, BR.
authors.forename: Andréa Kazumi
authors.initials: AK
authors.lastname: Shimada
authors.affiliation: Universidade Federal de São Paulo - UNIFESP, São Paulo, SP, BR.
authors.forename: Nilceo Schwery
authors.initials: NS
authors.lastname: Michalany
authors.affiliation: Hospital Israelita Albert Einstein - HIAE, São Paulo, SP, BR.
authors.forename: Ana Rita de Araújo Burgos
authors.initials: AR
authors.lastname: Manhani
authors.affiliation: Faculdade de Medicina do ABC - FMABC, Santo André, SP, BR.
authors.forename: Auro Del
authors.initials: AD
authors.lastname: Giglio