title: Gram Scale Conversion of R-BINAM to R-NOBIN.
abstract: A mild, operationally simple, and single-step transition-metal-free protocol for the synthesis of enantiomerically pure (R)-(+)-2'-amino-1,1'-binaphthalen-2-ol (R-NOBIN) from (R)-(+)-1,1'-binaphthyl-2,2'-diamine (R-BINAM) is reported. The one-pot conversion proceeds with good yield and shows no racemization. The hydroxyl on the R-NOBIN product was shown to have come from water in the reaction medium via an H2(18)O study. The correct value of the specific rotation of R-NOBIN was reported.
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Arlington , Arlington, Texas 76019, United States.
authors.forename: Darshan C
authors.initials: DC
authors.lastname: Patel
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Arlington , Arlington, Texas 76019, United States.
authors.forename: Zachary S
authors.initials: ZS
authors.lastname: Breitbach
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Arlington , Arlington, Texas 76019, United States.
authors.forename: Ross M
authors.initials: RM
authors.lastname: Woods
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Arlington , Arlington, Texas 76019, United States.
authors.forename: Yeeun
authors.initials: Y
authors.lastname: Lim
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Arlington , Arlington, Texas 76019, United States.
authors.forename: Andy
authors.initials: A
authors.lastname: Wang
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Arlington , Arlington, Texas 76019, United States.
authors.forename: Frank W
authors.initials: FW
authors.lastname: Foss
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Arlington , Arlington, Texas 76019, United States.
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Armstrong