title: Prevalence and recurrence rate of perianal abscess--a population-based study, Sweden 1997-2009.
abstract: BACKGROUND
  The aim of this study was to assess the impact of diabetes mellitus, Crohn's disease, HIV/aids, and obesity on the prevalence and readmission rate of perianal abscess.
  
  
  METHODS
  The study cohort was based on the Swedish National Patient Register and included all patients treated for perianal abscess in Sweden 1997-2009. The prevalence and risk for readmission were assessed in association with four comorbidity diagnoses: diabetes mellitus, Crohn's disease, HIV, and/or AIDS and obesity.
  
  
  RESULTS
  A total of 18,877 patients were admitted during the study period including 11,138 men and 4557 women (2.4:1). Crohn's disease, diabetes, and obesity were associated with a significantly higher prevalence of perianal abscess than an age- and gender-matched background population (p < 0.05). In univariate analysis, neither age nor gender had any significant impact on the risk for readmission. In a multivariate Cox proportional hazard analysis, Crohns disease was the only significant risk factor for readmission of perianal abscess.
  
  
  CONCLUSIONS
  Crohn's disease, diabetes, and obesity increase the risk for perianal abscess. Of these, Crohn's and HIV has an impact on readmission. The pathogenesis and the influence of diabetes and obesity need further research if we are to understand why these diseases increase the risk for perianal abscess but not its recurrence.
authors.affiliation: Department of Surgical and Perioperative Science, Umeå University, 901 85, Umeå, Sweden. karin.adamo@umu.se.
authors.forename: Karin
authors.initials: K
authors.lastname: Adamo
authors.affiliation: Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Sandblom
authors.affiliation: Department of Surgical and Perioperative Science, Umeå University, 901 85, Umeå, Sweden.
authors.forename: Fredrik
authors.initials: F
authors.lastname: Brännström
authors.affiliation: Department of Surgical and Perioperative Science, Umeå University, 901 85, Umeå, Sweden.
authors.forename: Karin
authors.initials: K
authors.lastname: Strigård
mesh_terms: D000038:Abscess / Q000453:epidemiology*; D000328:Adult; D001003:Anal Canal / Q000382:microbiology* / Q000473:pathology*; D015897:Comorbidity; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D008297:Male; D010343:Patient Admission; D015995:Prevalence; D016016:Proportional Hazards Models; D012008:Recurrence; D013548:Sweden / Q000453:epidemiology
keywords: Perianal abscess; Prevalence; Readmission; Risk factor; Sweden