title: Csp(3)-P versus Csp(2)-P Bond Formation: Catalyst-Controlled Highly Regioselective Tandem Reaction of Ene-Yne-Ketones with H-Phosphonates.
abstract: Under copper-catalyzed or base-promoted conditions, a wide range of ene-yne-ketones react with H-phosphonates to afford various phosphorylated furans in good yields. A copper carbene generation or a Michael addition is proposed as the key step in the selective construction of the Csp(3)-P or Csp(2)-P bond, which is supported by carbene capture reactions and interval (31)P NMR experiments. Furthermore, this method features inexpensive metal catalysts, no usage of oxidant, and high atom economy, which make it attractive and practical.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Yu
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Songjian
authors.initials: S
authors.lastname: Yi
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Chuanle
authors.initials: C
authors.lastname: Zhu
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Weigao
authors.initials: W
authors.lastname: Hu
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Bingjie
authors.initials: B
authors.lastname: Gao
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang