title: Sugar-based novel chiral macrocycles for inclusion applications and chiral recognition.
abstract: A convergent template assisted synthesis of sugar-based chiral macrocycles has been achieved. The host-guest inclusion studies have revealed significant interactions of the synthesized macrocycle with primary over secondary ammonium salt. The chiral macrocyle also discriminates between D- and L-phenylalanine methyl ester hydrochlorides as revealed by (1)H NMR spectral studies on the mixture of the host and the guest molecules.
authors.affiliation: Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi 110007, India.
authors.forename: Ankita
authors.initials: A
authors.lastname: Singh
authors.affiliation: Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi 110007, India.
authors.forename: Vinod
authors.initials: V
authors.lastname: Khatri
authors.affiliation: Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi 110007, India.
authors.forename: Shashwat
authors.initials: S
authors.lastname: Malhotra
authors.affiliation: Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi 110007, India. Electronic address: ashokenzyme@gmail.com.
authors.forename: Ashok K
authors.initials: AK
authors.lastname: Prasad
mesh_terms: D005944:Glucosamine / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012492:Salts / Q000737:chemistry
chemical_list: D047028:Macrocyclic Compounds; D012492:Salts; D005944:Glucosamine
keywords: Benzyl ammonium perchlorate; Chiral recognition; Click reaction; Macrocycle; Phenylalanine; Template assisted