title: Current recommendations on managing tuberculosis patients with diabetes & its epidemiology.
abstract: OBJECTIVE
  Tuberculosis (TB) & Diabetes Mellitus (DM) are common diseases globally & both are mutually on rising trend, and co-existing together. To analyze the effect of TB on diabetes by causing hyperglycemia and causing impaired glucose tolerance. Impaired glucose tolerance that is one of the major risk factor for developing diabetes.
  
  
  METHODS
  Literature study regarding co-association of TB & DM with its complications and management through published articles. The drugs used to treat tuberculosis especially rifampicin and isoniazid interacts with oral anti-diabetic drugs and can lead to suboptimal glycemic control. Therefore the interaction of diabetes and tuberculosis is at multiple levels exacerbating each other. DM is also well recognized as an independent risk factor for lower respiratory tract infection. Infection with, staphylococcus aureus, gram negative bacteria, and fungi occur more frequently in diabetics.
  
  
  CONCLUSIONS
  The prevalence of diabetes globally is projected to rise from the current estimate of 150 million to 200 million in 2010 and to 300 million (5.4%) in 2025. The potential for increase in the number of cases of diabetes is greatest in Asia. It is an emerging public health problem leading in an associated significant proportion. This article reviews the association between diabetes and tuberculosis and suggests appropriate management for these conditions.
authors.affiliation: Department of Pharmacology, General Hospital of Chongqing Iron and Steel Group, District Dadukou, 400081 Chongqing, China. Electronic address: chunlandeng@outlook.com.
authors.forename: Chunlan
authors.initials: C
authors.lastname: Deng
authors.affiliation: Department of Pharmacology, General Hospital of Chongqing Iron and Steel Group, District Dadukou, 400081 Chongqing, China. Electronic address: 37454363@qq.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Pharmacology, General Hospital of Chongqing Iron and Steel Group, District Dadukou, 400081 Chongqing, China. Electronic address: 270319551@qq.com.
authors.forename: Yilan
authors.initials: Y
authors.lastname: Liao
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology / Q000627:therapeutic use; D001786:Blood Glucose / Q000187:drug effects; D048909:Diabetes Complications; D019468:Disease Management; D006801:Humans; D015995:Prevalence; D014376:Tuberculosis / Q000150:complications* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*
chemical_list: D000995:Antitubercular Agents; D001786:Blood Glucose
keywords: Diabetes mellitus; Epidemic; Infection; Tuberculosis