title: Difficult Diagnosis between B Cell Lymphoma and Classical Hodgkin's Lymphoma.
abstract: Although primary mediastinal large B-cell lymphoma and classic Hodgkin lymphoma of nodular sclerosis type are distinct disease, they share several clinical characteristics and biologic features. However, there are mediastinal lymphomas that not fit in either category. These types of lymphomas are recognized as mediastinal gray zone lymphomas. Gray zone lymphomas are lymphatic tumors that cannot be assigned to a defined lymphoma entity due to morphological, clinical, or genetic reasons. In this report, we present a case of a 22 year-old-Hispanic-female diagnosed with B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Hodgkin lymphoma.
authors.forename: Yaixa
authors.initials: Y
authors.lastname: Rentas Torres
authors.forename: Joshua L
authors.initials: JL
authors.lastname: Rodríguez-López
authors.forename: Maria
authors.initials: M
authors.lastname: Valentin
authors.forename: Hector
authors.initials: H
authors.lastname: Silva
mesh_terms: D000944:Antigens, Differentiation, B-Lymphocyte / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001402:B-Lymphocytes / Q000737:chemistry / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D003371:Cough / Q000209:etiology; D003520:Cyclophosphamide / Q000008:administration & dosage; D057210:Delayed Diagnosis; D003937:Diagnosis, Differential; D019468:Disease Management; D004317:Doxorubicin / Q000008:administration & dosage; D004417:Dyspnea / Q000209:etiology; D005260:Female; D006689:Hodgkin Disease / Q000175:diagnosis; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology; D049268:Positron-Emission Tomography; D011241:Prednisone / Q000008:administration & dosage; D011644:Puerperal Disorders / Q000175:diagnosis; D000069283:Rituximab / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage; D055815:Young Adult
chemical_list: D000944:Antigens, Differentiation, B-Lymphocyte; D000951:Antigens, Neoplasm; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone