title: Follicular fluid norepinephrine and dopamine concentrations are higher in polycystic ovary syndrome.
abstract: The aim of the present study was to compare follicular fluid (FF) levels of norepinephrine (NE) and dopamine (DA) in polycystic ovary syndrome (PCOS) and non-PCOS patients who underwent in vitro fertilization (IVF). Forty-seven PCOS patients (study group) and 61 patients with male factor infertility (control group) who underwent IVF using GnRH agonist protocol were recruited. Concentrations of NE and DA were measured in FF specimens of all patients. Demographic characteristics were comparable between the groups. Significantly higher levels of NE were measured in FF of PCOS patients (median: 61.05 nmol/l) compared to those with male infertility (median: 49.82 nmol/l). Similarly, significantly higher levels of DA were measured in FF of PCOS patients (median: 23.70 nmol/l) compared to those with male infertility (median: 18.28 nmol/l). In conclusion, the FF concentrations of both catecholamine are increased in PCOS patients when compared to non-PCOS patients.
authors.affiliation: a Department of Obstetrics and Gynecology , Ankara University School of Medicine , Ankara , Turkey and.
authors.forename: Natı
authors.initials: N
authors.lastname: Musalı
authors.affiliation: a Department of Obstetrics and Gynecology , Ankara University School of Medicine , Ankara , Turkey and.
authors.forename: Batuhan
authors.initials: B
authors.lastname: Özmen
authors.affiliation: a Department of Obstetrics and Gynecology , Ankara University School of Medicine , Ankara , Turkey and.
authors.forename: Yavuz Emre
authors.initials: YE
authors.lastname: Şükür
authors.affiliation: b Department of Medical Biochemistry , Ankara University School of Medicine , Ankara , Turkey.
authors.forename: Berrin İmge
authors.initials: Bİ
authors.lastname: Ergüder
authors.affiliation: a Department of Obstetrics and Gynecology , Ankara University School of Medicine , Ankara , Turkey and.
authors.forename: Cem Somer
authors.initials: CS
authors.lastname: Atabekoğlu
authors.affiliation: a Department of Obstetrics and Gynecology , Ankara University School of Medicine , Ankara , Turkey and.
authors.forename: Murat
authors.initials: M
authors.lastname: Sönmezer
authors.affiliation: a Department of Obstetrics and Gynecology , Ankara University School of Medicine , Ankara , Turkey and.
authors.forename: Bülent
authors.initials: B
authors.lastname: Berker
authors.affiliation: a Department of Obstetrics and Gynecology , Ankara University School of Medicine , Ankara , Turkey and.
authors.forename: Ruşen
authors.initials: R
authors.lastname: Aytaç
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D005307:Fertilization in Vitro; D015571:Follicular Fluid / Q000378:metabolism*; D006801:Humans; D007247:Infertility, Female / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D011085:Polycystic Ovary Syndrome / Q000378:metabolism*; D055815:Young Adult
chemical_list: D004298:Dopamine; D009638:Norepinephrine
keywords: Catecholamine; dopamine; in vitro fertilization; norepinephrine; polycystic ovary syndrome