title: An Unusual Case of Angiotensin-Converting-Enzyme Inhibitor-Related Penile Angioedema with Evolution to the Oropharynx.
abstract: A 52-year-old African American male with a long history of poorly controlled hypertension presented to the emergency department (ED) with two days of genital edema and pain. During ED work-up, the patient developed sudden onset of non-pitting, non-pruritic, and non-urticarial upper lip edema. Review of his antihypertensive medication list revealed that he normally took benazepril, highly suggestive of a diagnosis of angiotensin-converting-enzyme inhibitor-related angioedema (ACEI-RA). We present the first reported case of penile ACEI-RA that progressed to involve the oropharynx. The ED management of the condition and some of the newer treatment options available for ACEI-RA is also briefly discussed.
authors.affiliation: Keck School of Medicine of the University of Southern California, Los Angeles County + University of Southern California (LAC+USC), Department of Emergency Medicine, Los Angeles, California.
authors.forename: Jonathan G
authors.initials: JG
authors.lastname: Wagner
authors.affiliation: Keck School of Medicine of the University of Southern California, Los Angeles County + University of Southern California (LAC+USC), Department of Emergency Medicine, Los Angeles, California.
authors.forename: Elias M
authors.initials: EM
authors.lastname: Bench
authors.affiliation: Keck School of Medicine of the University of Southern California, Los Angeles County + University of Southern California (LAC+USC), Department of Emergency Medicine, Los Angeles, California.
authors.forename: Lee
authors.initials: L
authors.lastname: Plantmason
mesh_terms: D000437:Alcoholism / Q000150:complications; D000799:Angioedema / Q000139:chemically induced*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D001552:Benzazepines / Q000009:adverse effects*; D006801:Humans; D008046:Lip / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009960:Oropharynx / Q000187:drug effects*; D010409:Penile Diseases / Q000139:chemically induced*; D010413:Penis / Q000187:drug effects
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D001552:Benzazepines; C044946:benazepril