title: Chemical constituents of Eugenia catharinae and their antioxidant activity.
abstract: Nine compounds were isolated from the leaves of Eugenia catharinae, namely monomethyl olivetol (1), β-sitosterol (2), stigmasterol (3), uvaol (4), erythrodiol (5), rotundic acid (6), quercetin (7), catechin (8) and myricitrin (9). The structures of 1-9 were established through analysis of their spectroscopic (1H and13C NMR) and spectrometric (MS) data. Compounds 1 and 6 are reported the first time in the Eugenia genus. In addition, these data were compared with those reported in the literature. The antioxidant activity of plant samples and compounds was measured using the DPPH radical scavenging assay. Flavonoids 7, 8, 9 and the ethanolic extract showed the best results, with IC50values of 20.94 μM, 44.20 μM, 30.01 μM and 58.82 μg/mL, respectively.
authors.affiliation: a Laboratório de Química de Produtos Naturais, Departamento de Química , Universidade Federal de Santa Catarina , Florianópolis , Brazil.
authors.forename: Henrique H
authors.initials: HH
authors.lastname: Moresco
authors.affiliation: a Laboratório de Química de Produtos Naturais, Departamento de Química , Universidade Federal de Santa Catarina , Florianópolis , Brazil.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Colla
authors.affiliation: a Laboratório de Química de Produtos Naturais, Departamento de Química , Universidade Federal de Santa Catarina , Florianópolis , Brazil.
authors.forename: Ingrid D
authors.initials: ID
authors.lastname: Cavalcante
authors.affiliation: a Laboratório de Química de Produtos Naturais, Departamento de Química , Universidade Federal de Santa Catarina , Florianópolis , Brazil.
authors.forename: Gustavo S
authors.initials: GS
authors.lastname: Queiroz
authors.affiliation: a Laboratório de Química de Produtos Naturais, Departamento de Química , Universidade Federal de Santa Catarina , Florianópolis , Brazil.
authors.forename: Moacir G
authors.initials: MG
authors.lastname: Pizzolatti
authors.affiliation: a Laboratório de Química de Produtos Naturais, Departamento de Química , Universidade Federal de Santa Catarina , Florianópolis , Brazil.
authors.forename: Inês M C
authors.initials: IMC
authors.lastname: Brighente
keywords: DPPH; Eugenia catharinae; monomethyl olivetol; rotundic acid