title: [A case of SRY positive sex reversal in a domestic cat].
abstract: The present case report describes a stray cat with a female appearance. The new owners requested to neuter the animal. During surgery the veterinarian could not find any gonadal tissue. After puberty the cat showed more and more male behaviour. The owners of the cat were interested to know the cause of the abnormal behaviour, but forbid any further clinical tests or surgery. Based upon cytogenetic and molecular genetic experiments a diagnosis became possible. The uniform karyotype (38,XY) was in accordance with the karyotype of a male cat and it was possible to amplify the SR Y gene by PCR. The cat represents a case of SRYpositive sex reversal.
authors.forename: A
authors.initials: A
authors.lastname: Pieńkowska-Schelling
authors.forename: D
authors.initials: D
authors.lastname: Becker
authors.forename: B
authors.initials: B
authors.lastname: Pineroli
authors.forename: C
authors.initials: C
authors.lastname: Schelling
mesh_terms: D000818:Animals; D002415:Cats; D012734:Disorders of Sex Development / Q000235:genetics / Q000662:veterinary*; D007621:Karyotyping / Q000662:veterinary; D008297:Male; D055748:SOXB1 Transcription Factors / Q000235:genetics*
chemical_list: D055748:SOXB1 Transcription Factors