title: Initial classification of pediatric hearing impairment using behavioral measures of early prelingual auditory development.
abstract: OBJECTIVE
  Determine the sensitivity, specificity, and accuracy of pediatric hearing loss classification using behavioral evidence of early prelingual auditory development (EPLAD). Validate behavioral measures of EPLAD.
  
  
  METHODS
  EPLAD was assessed in a prospective sample of hearing-impaired children using the infant-toddler meaningful auditory integration scale (ITMAIS/MAIS). Hearing losses were classified using tone-burst auditory brainstem response (ABR) and ITMAIS/MAIS scores. This process was repeated in a second retrospective sample.
  
  
  METHODS
  The prospective sample was comprised of 139 hearing-impaired children under five years of age. Approximately equal proportions of mild-moderate, severe, and profound losses were included. The second retrospective sample was comprised of case records for 144 hearing-impaired children meeting the same selection criteria. This sample contained more than 80% profound losses.
  
  
  RESULTS
  EPLAD trajectories reached different asymptotes after two years of age, depending on the severity of hearing loss, allowing children over this age to be classified. The sensitivity of EPLAD classifications was over 90%; specificity was over 82%; and accuracy was over 88%.
  
  
  CONCLUSIONS
  Behavioral evidence of EPLAD provides an initial means of classifying pediatric hearing losses which can facilitate initial treatment options prior to diagnostic evaluation with tone-burst ABR.
authors.affiliation: a Hearing Center/Hearing & Speech Laboratory, Department of Otorhinolaryngology Head & Neck Surgery , West China Hospital, Sichuan University , Chengdu , Sichuan , China and.
authors.forename: Siyu
authors.initials: S
authors.lastname: Liang
authors.affiliation: b House Clinic , Los Angeles , California , USA.
authors.forename: Sigfrid D
authors.initials: SD
authors.lastname: Soli
authors.affiliation: a Hearing Center/Hearing & Speech Laboratory, Department of Otorhinolaryngology Head & Neck Surgery , West China Hospital, Sichuan University , Chengdu , Sichuan , China and.
authors.forename: Yun
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: a Hearing Center/Hearing & Speech Laboratory, Department of Otorhinolaryngology Head & Neck Surgery , West China Hospital, Sichuan University , Chengdu , Sichuan , China and.
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.affiliation: a Hearing Center/Hearing & Speech Laboratory, Department of Otorhinolaryngology Head & Neck Surgery , West China Hospital, Sichuan University , Chengdu , Sichuan , China and.
authors.forename: Zhaoli
authors.initials: Z
authors.lastname: Meng
mesh_terms: D000161:Acoustic Stimulation; D000367:Age Factors; D001301:Audiometry, Pure-Tone; D001307:Auditory Perception; D001309:Auditory Threshold; D002652:Child Behavior; D002657:Child Development; D002675:Child, Preschool; D042241:Early Diagnosis; D016057:Evoked Potentials, Auditory, Brain Stem; D006319:Hearing Loss, Sensorineural / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D007223:Infant; D018730:Infant Behavior; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012720:Severity of Illness Index
keywords: Early prelingual auditory development; hearing loss; infant-toddler meaningful auditory integration scale