title: A New Fluorescent Sensor Based on Bisindolizine Derivative.
abstract: A fluorescent sensor based on 1,2,1',2'- Tetra(methoxycarbonyl)- 3,3'- bis(p-methylbenzoyl)- 7,7'-bisindolizine (MBI) showing excellent selectivity towards Fe(3+) ions was developed. Under optimized experimental conditions, the fluorescence intensity of 1,2,1',2'- Tetramethoxycarbonyl- 3,3'- bis(p-methylbenzoyl)- 7,7'-bisindolizine was quenched linearly by Fe(3+) ions in the range of 2.00 × 10(-2) to 4.76 × 10(-3) M. The limit of detection was found to be 3.17 × 10(-3) M. The mechanism for quenching was investigated. The developed sensor was applied for the determination of Fe(3+) in pharmaceutical samples.
authors.affiliation: Postgraduate and Research Department of Chemistry, Maharaja's College, Ernakulam, Kerala, 682011, India. dranithagirishkumar@gmail.com.
authors.forename: Anitha
authors.initials: A
authors.lastname: I
authors.affiliation: TMJM Govt. College, Manimalakunnu, Ernakulam, Kerala, 686662, India.
authors.forename: Sheela Gopal
authors.initials: SG
authors.lastname: M
authors.affiliation: Department of Applied Chemistry, Cochin University of Science and Technology, Kochi, 682 022, India.
authors.forename: Divya
authors.initials: D
authors.lastname: Thomas
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D002214:Capsules / Q000032:analysis*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007212:Indolizines / Q000737:chemistry*; D007501:Iron / Q000032:analysis*; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000737:chemistry; D013050:Spectrometry, Fluorescence
chemical_list: D002214:Capsules; D005456:Fluorescent Dyes; D007212:Indolizines; D004364:Pharmaceutical Preparations; D007501:Iron
keywords: Bisindolizine; Fe3+; Fluorescence quenching; Fluorescent sensor; Microwave synthesis