title: De novo gastric adenocarcinoma 1 year after sleeve gastrectomy in a transplant patient.
abstract: BACKGROUND
  It has been reported in the literature that upper gastrointestinal malignancies after bariatric surgery are mostly gastro-esophageal, although it is not clear whether bariatric surgery represents a risk factor for the development of esophageal and/or gastric cancer. We report a case of a de novo gastric adenocarcinoma occurring in a transplant patient 1 year after a laparoscopic sleeve gastrectomy.
  
  
  METHODS
  A 44 year-old woman with a BMI of 38kg/m(2), hypertension, type 1 diabetes mellitus, multiple malignancies and a pancreas transplant underwent laparoscopic sleeve gastrectomy. The patient presented with intense dysphagias during the follow up. Studies were performed and the diagnoses of grade 2/3 adenocarcinoma were made. The patient underwent a robotic assisted total gastrectomy with a roux-en-y intracorporeal esophagojejunostomy. The procedure resulted in multiple metastasic lymph nodes, focal and transmural invasions to multiple organs with a tumor free margin resection. The patient presented with a postoperative pleural effusion, with no further complications.
  
  
  CONCLUSIONS
  The diagnosis of gastroesophageal cancer after bariatric surgery is usually late since these patients have common upper gastrointestinal symptoms related to the procedure that could delay the diagnosis. De novo gastric cancer after sleeve gastrectomy has only been reported in one instance, in contrast with other bariatric surgery procedures.
  
  
  CONCLUSIONS
  No direct relation has been established between sleeve gastrectomy and the development of gastric cancer. Robotic procedures allow for complex multiorgan resections, while preserving the benefits of minimally invasive surgery.
authors.affiliation: Minimally Invasive & Robotic Surgery, University of Illinois Hospital and Health Science System, Chicago, IL, United States. Electronic address: mmasrur@uic.edu.
authors.forename: M
authors.initials: M
authors.lastname: Masrur
authors.affiliation: Minimally Invasive & Robotic Surgery, University of Illinois Hospital and Health Science System, Chicago, IL, United States.
authors.forename: E
authors.initials: E
authors.lastname: Elli
authors.affiliation: Minimally Invasive & Robotic Surgery, University of Illinois Hospital and Health Science System, Chicago, IL, United States.
authors.forename: L F
authors.initials: LF
authors.lastname: Gonzalez-Ciccarelli
authors.affiliation: Minimally Invasive & Robotic Surgery, University of Illinois Hospital and Health Science System, Chicago, IL, United States.
authors.forename: P C
authors.initials: PC
authors.lastname: Giulianotti
keywords: Gastric cancer; Gastric cancer in transplant patient; Novo gastric adenocarcinoma; Robotic gastrectomy; Sleeve gastrectomy