title: The mouse prostate: a basic anatomical and histological guideline.
abstract: Despite substantial similarities in embryological, cellular and molecular biology features, human and mouse prostates differ in organ morphology and tissue architecture. Thus, a clear understanding of the anatomy and histology of the mouse prostate is essential for the identification of urogenital phenotypes in genetically engineered mice, as well as for the study of the etiology, development, and treatment of human prostatic diseases for which mouse models are used. The purpose of this manuscript is to provide a brief guide for the dissection of the mouse prostate and the identification of its different lobes and histology, to both basic researchers and medical pathologists who are unfamiliar with mouse tissues.
authors.affiliation: University School of Medicine, Detroit, MI, USA. dmiragai@med.wayne.edu.
authors.forename: Daniel S M
authors.initials: DS
authors.lastname: Oliveira
authors.forename: Sijana
authors.initials: S
authors.lastname: Dzinic
authors.forename: Alan I
authors.initials: AI
authors.lastname: Bonfil
authors.forename: Allen D
authors.initials: AD
authors.lastname: Saliganan
authors.forename: Shijie
authors.initials: S
authors.lastname: Sheng
authors.forename: R Daniel
authors.initials: RD
authors.lastname: Bonfil
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004801:Eosine Yellowish-(YS) / Q000737:chemistry; D006416:Hematoxylin / Q000737:chemistry; D006653:Histology; D006801:Humans; D008297:Male; D051379:Mice; D023421:Models, Animal; D010641:Phenotype; D011467:Prostate / Q000033:anatomy & histology* / Q000473:pathology* / Q000601:surgery; D051381:Rats; D013045:Species Specificity
chemical_list: D004801:Eosine Yellowish-(YS); D006416:Hematoxylin