title: Sub-cutaneous histiocytic sarcoma in a child: a case report.
abstract: BACKGROUND
  Histiocytic sarcoma (HS) is a rare hematologic malignancy with morphologic and immunophenotypic evidence of histiocytic differentiation. This tumor follows an aggressive clinical course.
  
  
  METHODS
  We report the case of a 14 year-old white girl who presented with a nodular lesion in the thigh, involving the skin and soft tissue. The histologic diagnosis retained was a HS.
  
  
  CONCLUSIONS
  HS is a rare neoplasm that may cause a diagnostic pitfall. Unfortunately, incomplete clinical data and histopathologic disparities in addition to the overall rarity of the neoplasms induced difficulties of management and of full appreciation of their clinical behavior.
authors.forename: Mona
authors.initials: M
authors.lastname: Mlika
authors.forename: Rim
authors.initials: R
authors.lastname: Hamrouni
authors.forename: Abdelfatteh
authors.initials: A
authors.lastname: Zeddini
authors.forename: Emna
authors.initials: E
authors.lastname: Braham
authors.forename: Olfa
authors.initials: O
authors.lastname: Ismail
authors.forename: Faouzi
authors.initials: F
authors.lastname: El Mezni
mesh_terms: D000293:Adolescent; D005260:Female; D054747:Histiocytic Sarcoma / Q000473:pathology*; D006801:Humans; D035583:Rare Diseases / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D040521:Subcutaneous Tissue / Q000473:pathology*