title: Access to 3-Acyl-(2H)-indazoles via Rh(III)-Catalyzed C-H Addition and Cyclization of Azobenzenes with α-Keto Aldehydes.
abstract: The rhodium(III)-catalyzed direct C-H functionalization of azobenzenes with ethyl glyoxalate and aryl glyoxals is described. This protocol provides the facile and efficient formation of various C3-acylated-(2H)-indazoles in moderate to high yields.
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: Taejoo
authors.initials: T
authors.lastname: Jeong
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Han
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: Sangil
authors.initials: S
authors.lastname: Han
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: Satyasheel
authors.initials: S
authors.lastname: Sharma
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: Jihye
authors.initials: J
authors.lastname: Park
authors.affiliation: Biocenter, Gyeonggi Institute of Science & Technology Promotion , Suwon 443-270, Republic of Korea.
authors.forename: Jong Suk
authors.initials: JS
authors.lastname: Lee
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: Jong Hwan
authors.initials: JH
authors.lastname: Kwak
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Jung
authors.affiliation: School of Pharmacy, Sungkyunkwan University , Suwon 440-746, Republic of Korea.
authors.forename: In Su
authors.initials: IS
authors.lastname: Kim
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006037:Glyoxal / Q000031:analogs & derivatives / Q000737:chemistry; D007191:Indazoles / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D001391:Azo Compounds; D007191:Indazoles; D007659:Ketones; D006037:Glyoxal; D012238:Rhodium; C009850:azobenzene