title: Antibacterial and antitumour activities of some plants grown in Turkey.
abstract: Screening of antibacterial and antitumour activities of 33 different extracts prepared with three types of solvents (water, ethanol and methanol) was conducted. The extracts were obtained from 11 different plant species grown in Turkey:Eryngium campestreL.,Alchemilla mollis(Buser) Rothm.,Dorycnium pentaphyllumScop.,Coronilla variaL.,Onobrychis oxyodontaBoiss.,Fritillaria ponticaWahlenb.,Asarum europaeumL.,Rhinanthus angustifoliusC. C. Gmelin,Doronicum orientaleHoffm.,Campanula glomerataL. andCampanula olympicaBoiss. Antibacterial activity against six bacteria was evaluated:Escherichia coli,Pseudomonas aeruginosa,Klebsiella pneumoniae,Streptococcus pyogenes,Staphylococcus aureusandStaphylococcus epidermidisby using disc diffusion and well diffusion methods.S. aureusandS. epidermidiswere most sensitive to the methanolic extract fromA. europaeum.S. pyogeneswas vulnerable to all used extracts ofD. orientale. In addition, ethanolic or methanolic extracts ofE. campestre,A. mollis,D. pentaphyllum,C. varia,R. angustifolius,C. glomerataandC. olympicadisplayed strong antibacterial activity against at least one of the tested gram-negative bacteria. The methanolic extract fromR. angustifoliusshowed a broad-spectrum activity against both gram-positive and gram-negative bacteria. Antitumour activity was evaluated withAgrobacterium-tumefaciens-induced potato disc tumour assay. Best antitumour activity was obtained with the aqueous extract fromA. europaeumand methanolic extract fromE. campestre(100% and 86% tumour inhibition, respectively).
authors.affiliation: Department of Biology, Gaziosmanpasa University , Tokat , Turkey.
authors.forename: Canan
authors.initials: C
authors.lastname: Usta
authors.affiliation: Department of Biology, Abant Izzet Baysal University , Bolu , Turkey.
authors.forename: Arzu Birinci
authors.initials: AB
authors.lastname: Yildirim
authors.affiliation: Department of Biology, Abant Izzet Baysal University , Bolu , Turkey.
authors.forename: Arzu Ucar
authors.initials: AU
authors.lastname: Turker
keywords: antibacterial; antitumour; pathogenic bacteria