title: Yellow Nail Syndrome Associated with Pericarditis and Pericardial Effusion: a Case Report.
abstract: Yellow nail syndrome (YNS) is an uncommon condition characterized by nail changes, lymphedema, in addition to pulmonary disorders and pleural effusion. Pericarditis and non-cardiac disorders can evolve with pericardial effusions including autoimmune conditions, hypothyroidism, malignancies, tuberculosis, and uremia. A 72-year-old Brazilian woman under treatment for arterial hypertension and hypothyroidism was admitted with pericarditis and pericardial effusion concomitant with yellow nail syndrome. She denied tobacco smoking, alcohol abuse, and similar disorders in her family. Clinical and complementary evaluation ruled out infectious diseases, malignancies, and autoimmune disorders as etiologic factors in this case. Hypothyroidism is a well-known cause of pericardial effusion, the vast majority in the absence of pericarditis, and has been described as an associated condition in some individuals with YNS. Case studies might contribute to better understanding of these causal or casual relationships.
authors.affiliation: Department of Internal Medicine, Armed Forces Hospital and Catholic University, Brasília-DF, Brazil .
authors.forename: Vitorino Modesto dos
authors.initials: VM
authors.lastname: Santos
authors.affiliation: Department of Pneumology, Armed Forces Hospital, Brasília-DF, Brazil.
authors.forename: Christiane Aires
authors.initials: CA
authors.lastname: Teixeira
authors.affiliation: Department of Pneumology, Armed Forces Hospital, Brasília-DF, Brazil.
authors.forename: Ana Carla Andrade
authors.initials: AC
authors.lastname: Almeida
authors.affiliation: Department of Internal Medicine, Armed Forces Hospital and Catholic University, Brasília-DF, Brazil .
authors.forename: Alessandra Maria Rodrigues Oliveira
authors.initials: AM
authors.lastname: Santos
authors.affiliation: Department of Internal Medicine, Hospital of West, Barreiras-BA, Brazil.
authors.forename: Kátia Rejane Marques
authors.initials: KR
authors.lastname: Brito
authors.affiliation: Department of Radiology, Armed Forces Hospital, Brasília-DF, Brazil.
authors.forename: Valerio Alves
authors.initials: VA
authors.lastname: Ferreira
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D006973:Hypertension / Q000628:therapy; D007037:Hypothyroidism / Q000209:etiology; D008209:Lymphedema / Q000209:etiology; D009260:Nail Diseases / Q000209:etiology; D010490:Pericardial Effusion / Q000209:etiology*; D010493:Pericarditis / Q000209:etiology*; D010996:Pleural Effusion / Q000209:etiology; D014511:Uremia / Q000209:etiology; D056684:Yellow Nail Syndrome / Q000175:diagnosis* / Q000503:physiopathology
keywords: Hypothyroidism; Pericardial effusion; Pericarditis; Yellow nail syndrome