title: Primary pulmonary collision tumor with three components in the underlying interstitial lung disease.
abstract: A collision tumor of the lung is relatively rare. We report a case of a 72-year-old man with a collision tumor consisting of three neoplastic components in the underlying interstitial lung disease. Computed tomography showed a parenchymal lesion with an air bronchogram. Transthoracic needle lung biopsy showed chronic inflammation, however, a malignant pulmonary tumor was clinically suspected. The patient underwent a right lower lobectomy with mediastinal lymph node dissection. The histological features of the surgical specimen showed lung cancer with three neoplastic components, which were squamous cell carcinoma, invasive mucinous adenocarcinoma, and invasive non-mucinous adenocarcinoma. To the best of our knowledge, this is the first documentation of a collision lung tumor with three components.
authors.affiliation: Department of General Thoracic Surgery, School of Medicine, Keio University Tokyo, Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Suzuki
authors.affiliation: Department of General Thoracic Surgery, School of Medicine, Keio University Tokyo, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Ohtsuka
authors.affiliation: Department of General Thoracic Surgery, School of Medicine, Keio University Tokyo, Japan.
authors.forename: Tai
authors.initials: T
authors.lastname: Hato
authors.affiliation: Department of General Thoracic Surgery, School of Medicine, Keio University Tokyo, Japan.
authors.forename: Ikuo
authors.initials: I
authors.lastname: Kamiyama
authors.affiliation: Department of General Thoracic Surgery, School of Medicine, Keio University Tokyo, Japan.
authors.forename: Taichiro
authors.initials: T
authors.lastname: Goto
authors.affiliation: Department of General Thoracic Surgery, School of Medicine, Keio University Tokyo, Japan.
authors.forename: Mitsutomo
authors.initials: M
authors.lastname: Kohno
authors.affiliation: Department of Pathology, School of Medicine, Keio University Tokyo, Japan.
authors.forename: Katsura
authors.initials: K
authors.lastname: Emoto
authors.affiliation: Department of Pathology, School of Medicine, Keio University Tokyo, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Hayashi
keywords: Collision tumor; interstitial lung disease; lung cancer