title: Prevalence of ESBLs-producing Pseudomonas aeruginosa isolates from different wards in a Chinese teaching hospital.
abstract: This study was to explore the molecular dissemination of P. aeruginosa producing extended spectrum β-lactamase (ESBLs) recovered from the different wards in a teaching hospital, Jilin. Among 240 isolates, 91 strains were isolated from burn wards and 149 strains from surgical wards. A total of 210 strains (87.5%) produced ESBLs, 30 strains (12.5%) didn't produce ESBLs. All ESBLs isolates showed identical antimicrobial susceptibility profiles. The genotypic prevalence of ESBLs for bla SHV-12, bla TEM-24, bla CTX-M-1, bla CTX-M-2, bla CTX-M-3, bla PER and bla VEB genes was 17.6%, 20.5%, 14.3%, 9.6%, 12.9%, 13.8% and 11.4% respectively. All P. aeruginosa strains producing ESBLs had three to six plasmids and contained class 1 integrons, which transferred resistance to E. coli C 600 by conjuation. The data indicated a high prevalence of ESBL among P. aeruginosa isolates in this region and their enzyme types were diverse.
authors.affiliation: Department of Surgery, Associated Hospital, Beihua University Jilin, China.
authors.forename: Zhilong
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Department of Surgery, Associated Hospital, Beihua University Jilin, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Niu
authors.affiliation: Department of Surgery, Associated Hospital, Beihua University Jilin, China.
authors.forename: Guangyu
authors.initials: G
authors.lastname: Chen
authors.affiliation: Department of Clinical Microbiology, School of Laboratory Medicine, Beihua University Jilin, China.
authors.forename: Mingcheng
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Clinical Microbiology, School of Laboratory Medicine, Beihua University Jilin, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Clinical Microbiology, School of Laboratory Medicine, Beihua University Jilin, China.
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Zhou
keywords: Nosocomial infection; Pseudomonas aeruginosa; expended spectrum-β-lactamases