title: [Onychocola canadensis Sigler in onychomycosis : A new dermatophyte-like mould in Germany].
abstract: Moulds or non-dermatophyte moulds (NDM) are being increasingly isolated as causative agent of onychomycoses. Known causes of a NDM-OM are Scopulariopsis brevicaulis, Fusarium, Aspergillus, Acremonium, Neoscytalidium dimidiatum, Arthrographis kalrae, and Chaetomium. In this article, 5 patients with suspected nail infection due to Onychocola canadensis are reported for the first time in Germany. Systemic antifungal agents are not considered to be effective in NDM onychomycosis. In individual cases, however, terbinafine seems to be effective in Onychocola canadensis infection of the nails. Treatment of choice represents, however, nontraumatic nail avulsion using 40 % urea ointment followed by antifungal nail lacquer with ciclopirox olamine or amorolfine.
authors.affiliation: Labor für medizinische Mikrobiologie, Mölbiser Hauptstraße 8, 04571, Rötha/OT Mölbis, Deutschland. nenoff@mykologie-experten.de.
authors.forename: P
authors.initials: P
authors.lastname: Nenoff
authors.affiliation: Institut für Medizinische Diagnostik Greifswald, Pappelallee 1, 17489, Greifswald, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Schorlemmer
authors.affiliation: Labor für medizinische Mikrobiologie, Mölbiser Hauptstraße 8, 04571, Rötha/OT Mölbis, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Uhrlaß
authors.affiliation: Hautarztpraxis Dr. Annegret Baunacke, Hauptstr. 58, 01454, Radeberg, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Baunacke
authors.affiliation: Hautarztpraxis Dr. Annegret Baunacke, Hauptstr. 58, 01454, Radeberg, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Baunacke
authors.affiliation: Medizinisches Labor Ostsachsen, Mikrobiologie Görlitz, Alfred-Fehler-Straße 18, 02827, Görlitz, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Friedrichs
authors.affiliation: Hautarztpraxis Dr. Jens Iffländer, Schützenstr. 8, 14943, Luckenwalde, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Iffländer
authors.affiliation: Hautarztpraxis Dr. Barbara und Ellen Syhre, Leipziger Straße 12, 04720, Döbeln, Deutschland.
authors.forename: E
authors.initials: E
authors.lastname: Syhre
authors.affiliation: Hautarztpraxis Dr. Angela Schneider, Rimbeckerstraße 34a, 38855, Wernigerode, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Schneider
authors.affiliation: Labor für medizinische Mikrobiologie, Mölbiser Hauptstraße 8, 04571, Rötha/OT Mölbis, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Krüger
authors.affiliation: Microbiological Laboratory/R&D Bioanalytics, Bruker Daltonik GmbH, Fahrenheitstr. 4, 28359, Bremen, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Maier
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D021821:Communicable Diseases, Emerging / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use*; D014009:Onychomycosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology; D020036:Onygenales / Q000302:isolation & purification*; D000077291:Terbinafine; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine
keywords: Ciclopirox olamine; DNA-Sequencing; Nail avulsion; Onychomycosis; Terbinafine