title: Metal-Free Catalyzed Regioselective Allylic Trifluoromethanesulfonylation of Aromatic Allylic Alcohols with Sodium Trifluoromethanesulfinate.
abstract: An efficient procedure for the preparation of allylic trifluoromethanesulfones with high regioselectivity from aromatic allylic alcohols/esters and NaSO2CF3 under transition-metal-free conditions is described. A wide range of functional groups were tolerated. This is the first example to realize different types of allylic alcohols, including primary, secondary, and tertiary allylic alcohols, all of which transferred to the corresponding products efficiently in good to excellent yields with readily available and inexpensive NaSO2CF3. The synthetic utility of the method was demonstrated by performing the reaction at gram scale.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.|School of Pharmaceutical Sciences, Gannan Medical University , Ganzhou, Jiangxi 341000, China.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Liao
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Guo
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Zhenming
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Tang
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510640, China.
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang