title: Lubinska Phenomenon: Simultaneous Bidirectional Axoplasmic Flow in Nerve Fibers.
abstract: Experiments on live mollusk neurons isolated with a neurite fragmentsat its various levels demonstrated that axoplasm is characterized by mechanical strain realized in the form of retraction up to complete invagination of the axoplasm into the soma. Changes in axon geometry were attributed to neuroplasm movement. It was found that the direction of axoplasm movement depends on the location of adhesion points. It was always simultaneous and oppositely directed, as is the case with contractile myofibrils. The formation of distant paired adhesion sites can promote moving away of the axoplasm mass and organelles carried by it. The velocity and activity of axoplasm movement depend on the quantity and intensity of adhesion points along the axon.
authors.affiliation: Laboratory of Functional Morphology and Physiology of the Neuron, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia. ossotnikov@mail.ru.
authors.forename: O S
authors.initials: OS
authors.lastname: Sotnikov
authors.affiliation: Laboratory of Functional Morphology and Physiology of the Neuron, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.
authors.forename: N Yu
authors.initials: NY
authors.lastname: Vasyagina
authors.affiliation: Laboratory of Functional Morphology and Physiology of the Neuron, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.
authors.forename: S S
authors.initials: SS
authors.lastname: Sergeeva
mesh_terms: D000818:Animals; D001370:Axonal Transport / Q000502:physiology*; D001369:Axons / Q000502:physiology; D008974:Mollusca / Q000166:cytology; D009412:Nerve Fibers / Q000502:physiology*
keywords: axon adhesion; axon retraction; axoplasmic flow; bidirectional axonal flow; neuronal migration