title: Mononeuritis multiplex in acquired amegakaryocytic thrombocytopenia.
abstract: Mononeuritis multiplex involves inflammation of two or more nerves, typically in unrelated parts of the body. It has been well described in bleeding disorders like idiopathic thrombocytopenic purpura (ITP) and Hemophilia. Acquired amegakaryocytic thrombocytopenia (AAT) is a bleeding diathesis characterized by thrombocytopenia but with reduced number of megakaryocytes in the bone marrow, as against ITP. Though AAT is a well described entity, peripheral nervous system manifestations have not been described so far. We report a young man who has presented with bleeding diathesis and mononeuritis multiplex due to AAT. The mechanism of development of mononeuritis multiplex and treatment options are discussed.
authors.affiliation: Department of Neurology, Mother Hospital, Thrissur, Kerala, India.
authors.forename: Firosh
authors.initials: F
authors.lastname: Khan
authors.affiliation: Department of Radiotherapy and Oncology, Government Medical College, Thrissur, Kerala, India.
authors.forename: Abdulkhader
authors.initials: A
authors.lastname: Shehna
authors.affiliation: Department of Pathology, MES Medical College Hospital, Perinthalmanna, Kerala, India.
authors.forename: Lekha
authors.initials: L
authors.lastname: Mukundan
keywords: Amegakaryocytic thrombocytopenia; mononeuritis multiplex; purpura