title: Resolution of innumerable cerebral Nocardia paucivorans abscesses after medical management.
abstract: Nocardia species are an infrequent cause of brain abscesses. We report a 50-year-old man with Nocardia paucivorans cerebral abscesses. Brain MRI revealed innumerable small ring-enhancing lesions. The patient initially responded to treatment with antibiotics and steroids, but experienced worsening after discontinuation of steroids. Brain biopsy performed to exclude central nervous system lymphoma produced nodular tissue with branching filaments on silver stain. Steroids were re-initiated and tapered slowly. The patient completed 1year of antibiotic therapy, after which he had no neurological symptoms and complete resolution of all brain abscesses on MRI.
authors.affiliation: Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 TC, Ann Arbor, MI 48109-5338, USA.
authors.forename: Nader
authors.initials: N
authors.lastname: Delavari
authors.affiliation: Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 TC, Ann Arbor, MI 48109-5338, USA.
authors.forename: Khoi D
authors.initials: KD
authors.lastname: Than
authors.affiliation: Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 TC, Ann Arbor, MI 48109-5338, USA.
authors.forename: Kevin S
authors.initials: KS
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 TC, Ann Arbor, MI 48109-5338, USA.
authors.forename: Paul E
authors.initials: PE
authors.lastname: McKeever
authors.affiliation: Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 TC, Ann Arbor, MI 48109-5338, USA.
authors.forename: Anthony C
authors.initials: AC
authors.lastname: Wang
authors.affiliation: Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 TC, Ann Arbor, MI 48109-5338, USA. Electronic address: adityap@med.umich.edu.
authors.forename: Aditya S
authors.initials: AS
authors.lastname: Pandey
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001922:Brain Abscess / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009615:Nocardia; D009617:Nocardia Infections / Q000188:drug therapy* / Q000473:pathology; D013256:Steroids / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D013256:Steroids
keywords: Brain abscess; Nocardia paucivorans; Nocardiosis