title: Autoimmune uveitis: study of treatment therapies.
abstract: Experimental autoimmune uveitis is an organ-specific T-cell mediated autoimmune disease characterized by inflammation and consequent destruction of the neural retina and adjacent tissues. Inflammation in experimental autoimmune uveitis may be induced in rodents by immunization with retinal antigens, such as interphotoreceptor retinoid-binding protein. We present a review of experimental studies that correlate primary immunobiological functions with this chronic disease and the possible use of molecules for the treatment of autoimmune uveitis.
authors.affiliation: Vision Institute, Universidade Federal de São Paulo - UNIFESP, São Paulo, SP, Brazil.
authors.forename: Alessandra Gonçalves
authors.initials: AG
authors.lastname: Commodaro
authors.affiliation: Department of Immunology, Instituto de Ciências Biomédicas, Universidade de São Paulo - USP, São Paulo, SP, Brazil.
authors.forename: Luciana de Deus Vieira de
authors.initials: Lde D
authors.lastname: Moraes
authors.affiliation: Laboratory of Immunochemistry of Instituto Butantan, São Paulo, SP, Brazil.
authors.forename: Denise Vilarinho
authors.initials: DV
authors.lastname: Tambourgi
authors.affiliation: Instituto da Visão, Universidade Federal de São Paulo - UNIFESP, São Paulo, SP, Brazil.
authors.forename: Rubens
authors.initials: R
authors.lastname: Belfort
authors.affiliation: Laboratory of Immunochemistry of Instituto Butantan, São Paulo, SP, Brazil.
authors.forename: Osvaldo Augusto
authors.initials: OA
authors.lastname: Sant'Anna
authors.affiliation: Instituto Israelita de Ensino e Pesquisa Albert Einstein - IIEPAE, São Paulo, SP, Brazil.
authors.forename: Luiz Vicente
authors.initials: LV
authors.lastname: Rizzo