title: Staged treatment of thoracic and lumbar spinal tuberculosis with flow injection abscess.
abstract: The study was to investigate the feasibility and effectiveness of posterior-only approach combining with puncture drainage under CT-guide in staged treatment of thoracic and lumbar spinal tuberculosis with flow injection abscess. We retrospectively analyzed 15 patients (came from 72 cases with thoracic and lumbar spinal tuberculosis) with flow injection abscesses underwent surgery from January 2007 to February 2009, and evaluated the American Spinal Injury Association (ASIA) scoring system of nerve function, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), abscess absorption time and the Oswestry Disability Index (ODI), preoperatively and postoperatively. 15 patients were followed up for 13-37 months, no recurrence of tuberculosis, no fixation loosening and neurologic symptoms aggravated. The flow injection abscesses are absorbed within 3-6 months postoperative operation. In final follow-up, ESR went down to 5.2±2.1 mm/h from preoperative 79.6±14.8 mm/h, CRP decreased from preoperative 49.3±7.5 mg/L to 1.8±0.7 mg/L, ODI changed from 75.13±20.15 to 16.72±8.62, all of them changed significantly (P<0.05). In conclusions, one-stage posterior debridement, interbody fusion, pedicle screw fixation and two-stage CT-guided interventional therapy were safe and effective in treatment of the thoracic and lumbar spinal tuberculosis with flow injection abscess.
authors.affiliation: Department of Spine Surgery, The Xiangya Hospital of Central South University 87# Xiangya Road, Changsha 410008, Hunan, People's Republic of China.
authors.forename: Hao
authors.initials: H
authors.lastname: Zeng
authors.affiliation: Department of Spine Surgery, The Xiangya Hospital of Central South University 87# Xiangya Road, Changsha 410008, Hunan, People's Republic of China.
authors.forename: Yupeng
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Spine Surgery, Hunan Provincial People's Hospital Changsha 410005, Hunan, People's Republic of China.
authors.forename: Xiongjie
authors.initials: X
authors.lastname: Shen
authors.affiliation: Department of Spine Surgery, The Xiangya Hospital of Central South University 87# Xiangya Road, Changsha 410008, Hunan, People's Republic of China.
authors.forename: Chengke
authors.initials: C
authors.lastname: Luo
authors.affiliation: Department of Spine Surgery, The Xiangya Hospital of Central South University 87# Xiangya Road, Changsha 410008, Hunan, People's Republic of China.
authors.forename: Zhengquan
authors.initials: Z
authors.lastname: Xu
authors.affiliation: Department of Spine Surgery, The Xiangya Hospital of Central South University 87# Xiangya Road, Changsha 410008, Hunan, People's Republic of China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Spine Surgery, Hunan Provincial People's Hospital Changsha 410005, Hunan, People's Republic of China.
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Spine Surgery, The Xiangya Hospital of Central South University 87# Xiangya Road, Changsha 410008, Hunan, People's Republic of China.
authors.forename: Xiyang
authors.initials: X
authors.lastname: Wang
keywords: Spinal tuberculosis; flow injection abscess; puncture drainage; staged treatment; thoracic and lumbar spine