title: Interleukin-15-activated cytokine-induced killer cells may sustain remission in leukemia patients after allogeneic stem cell transplantation: feasibility, safety and first insights on efficacy.
authors.affiliation: JW Goethe University Frankfurt, Hospital for Children and Adolescents, Department of Stem Cell Transplantation and Immunology, Germany eva.rettinger@kgu.de peter.bader@kgu.de.
authors.forename: Eva
authors.initials: E
authors.lastname: Rettinger
authors.affiliation: JW Goethe University Frankfurt, Hospital for Children and Adolescents, Department of Stem Cell Transplantation and Immunology, Germany.
authors.forename: Sabine
authors.initials: S
authors.lastname: Huenecke
authors.affiliation: JW Goethe University Frankfurt, Institute for Transfusion Medicine and Immunohematology, and German Red Cross Blood Donor Service Baden-Württemberg-Hessen, Department of Cellular Therapeutics / Cell Processing (GMP), Frankfurt/Main, Germany University of Washington, Department of Medicine/Hematology, Seattle, WA, USA.
authors.forename: Halvard
authors.initials: H
authors.lastname: Bonig
authors.affiliation: JW Goethe University Frankfurt, Hospital for Children and Adolescents, Department of Stem Cell Transplantation and Immunology, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Merker
authors.affiliation: JW Goethe University Frankfurt, Hospital for Children and Adolescents, Department of Stem Cell Transplantation and Immunology, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Jarisch
authors.affiliation: JW Goethe University Frankfurt, Hospital for Children and Adolescents, Department of Stem Cell Transplantation and Immunology, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Soerensen
authors.affiliation: JW Goethe University Frankfurt, Hospital for Children and Adolescents, Department of Stem Cell Transplantation and Immunology, Germany.
authors.forename: Andre
authors.initials: A
authors.lastname: Willasch
authors.affiliation: JW Goethe University Frankfurt, Department of Medicine II, Hematology, Oncology, Rheumatology and Infectious Diseases, Germany.
authors.forename: Gesine
authors.initials: G
authors.lastname: Bug
authors.affiliation: University Medical Center Ulm, Department of Pediatrics, Germany.
authors.forename: Ansgar
authors.initials: A
authors.lastname: Schulz
authors.affiliation: JW Goethe University Frankfurt, Hospital for Children and Adolescents, Department of Stem Cell Transplantation and Immunology, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Klingebiel
authors.affiliation: JW Goethe University Frankfurt, Hospital for Children and Adolescents, Department of Stem Cell Transplantation and Immunology, Germany eva.rettinger@kgu.de peter.bader@kgu.de.
authors.forename: Peter
authors.initials: P
authors.lastname: Bader
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D055612:Cytokine-Induced Killer Cells / Q000166:cytology / Q000187:drug effects / Q000276:immunology / Q000637:transplantation*; D005260:Female; D006086:Graft vs Host Disease / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D006239:Haplotypes; D018380:Hematopoietic Stem Cell Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D007223:Infant; D019409:Interleukin-15 / Q000494:pharmacology; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D015470:Leukemia, Myeloid, Acute / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D012008:Recurrence; D012074:Remission Induction; D014019:Tissue Donors; D014184:Transplantation, Homologous
chemical_list: D019409:Interleukin-15
keywords: HSCT; IL-15-activated; cytokine-induced killer cells; efficacy; immunological control; relapse