title: Primo Vessel Stressed by Lipopolysaccharide in Rabbits.
abstract: For tracking the primo vascular system, we observed the primo vessels in vivo in situ using the lipopolysaccharide (LPS) response in the lymphatic vessels of a rabbit. Injection of LPS (200 μg/kg) into the lymph nodes resulted in greatly stained primo vessels, which were swollen in some cases. We were able to obtain comparative images through alcian blue and diaminobenzidine staining, which clearly showed different morphologies of the primo vessels. The mechanism causing the response of the primo vessels to the injected LPS is still unclear; however, these results might be a first attempt at giving an explanation of the function of the primo vascular system and identifying the changes in the structure and function of the primo vascular system in response to an external stimulus such as an injection of LPS.
authors.affiliation: Department of Oriental Biomedical Engineering, Sangji University, Wonju, South Korea.
authors.forename: Hye-Rie
authors.initials: HR
authors.lastname: Lee
authors.affiliation: Department of Oriental Biomedical Engineering, Sangji University, Wonju, South Korea.
authors.forename: Min-Suk
authors.initials: MS
authors.lastname: Rho
authors.affiliation: Department of Oriental Medicine, Sangji University, Wonju, South Korea.
authors.forename: Ye-Ji
authors.initials: YJ
authors.lastname: Hong
authors.affiliation: Department of Biological Science, Sangji University, Wonju, South Korea.
authors.forename: Yae-Eun
authors.initials: YE
authors.lastname: Ha
authors.affiliation: Department of Animal Science and Biotechnology, Sangji University, Wonju, South Korea.
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Department of Oriental Biomedical Engineering, Sangji University, Wonju, South Korea.
authors.forename: Young-Il
authors.initials: YI
authors.lastname: Noh
authors.affiliation: Department of Oriental Biomedical Engineering, Sangji University, Wonju, South Korea.
authors.forename: Do-Young
authors.initials: DY
authors.lastname: Park
authors.affiliation: Department of Animal Science and Biotechnology, Sangji University, Wonju, South Korea.
authors.forename: Chang-Kyu
authors.initials: CK
authors.lastname: Kim
authors.affiliation: Department of Biomedical Laboratory Science, Sangji University, Wonju, South Korea.
authors.forename: Eun-Jung
authors.initials: EJ
authors.lastname: Kim
authors.affiliation: Department of Biomedical Laboratory Science, Sangji University, Wonju, South Korea.
authors.forename: In-Ho
authors.initials: IH
authors.lastname: Jang
authors.affiliation: Acupuncture, Moxibustion and Meridian Research Group, Korea Institute of Oriental Medicine, Daejeon, South Korea.
authors.forename: Suk-Yun
authors.initials: SY
authors.lastname: Kang
authors.affiliation: Department of Oriental Biomedical Engineering, Sangji University, Wonju, South Korea. Electronic address: sslee@sangji.ac.kr.
authors.forename: Sang-Suk
authors.initials: SS
authors.lastname: Lee
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D005260:Female; D008070:Lipopolysaccharides / Q000008:administration & dosage*; D008198:Lymph Nodes / Q000033:anatomy & histology / Q000737:chemistry / Q000502:physiology; D042601:Lymphatic Vessels / Q000033:anatomy & histology / Q000737:chemistry* / Q000502:physiology; D016740:Meridians; D011817:Rabbits; D013194:Staining and Labeling
chemical_list: D008070:Lipopolysaccharides
keywords: diaminobenzidine staining; inflammation response; lipopolysaccharide; lymph vessel; primo connectome; primo vascular system