title: Primary cutaneous lymphomas: diagnosis and treatment.
abstract: Primary cutaneous lymphomas (CLs) are a heterogeneous group of lymphoproliferative neoplasms, with lymphatic proliferation limited to the skin with no involvement of lymph nodes, bone marrow or viscera at the diagnosis. Cutaneous lymphomas originate from mature T-lymphocytes (65% of all cases), mature B-lymphocytes (25%) or NK cells. Histopathological evaluation including immunophenotyping of the skin biopsy specimen is the basis of the diagnosis, which must be complemented with a precise staging of the disease and identification of prognostic factors, to allow for the choice of the best treatment method as well as for the evaluation of the treatment results.
authors.affiliation: Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland. Head of the Department: Prof. Roman Nowicki MD, PhD.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Sokołowska-Wojdyło
authors.affiliation: Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland. Head of the Department: Prof. Zygmunt Adamski MD, PhD.
authors.forename: Karolina
authors.initials: K
authors.lastname: Olek-Hrab
authors.affiliation: Department of Pathology and Experimental Rheumatology, Medical University of Gdansk, Gdansk, Poland. Head of the Department: Prof. Ewa Bryl MD, PhD.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Ruckemann-Dziurdzińska
keywords: Sézary syndrome; mycosis fungoides; primary cutaneous lymphoma