title: Degree and Direction of Change of Body Weight in Cardiac Rehabilitation and Impact on Exercise Capacity and Cardiac Risk Factors.
abstract: Cardiac rehabilitation (CR) improves functional capacity and reduces mortality in patients with cardiovascular disease. It also improves cardiovascular risk factors and aids in weight reduction. Because of the increase in morbidly obese patients with cardiovascular disease, the prevalence of obesity and patterns of weight change in those undergoing CR merit fresh study. We studied 1,320 participants in a 12-week CR program at our academic medical center. We compared 5 categories: 69 class III obese (body mass index [BMI] ≥40) patients, 128 class II obese patients (BMI 35.0 to 39.9), 318 class I obese patients (BMI 30.0 to 34.9), 487 overweight patients (BMI 25.0 to 29.9), and 318 normal weight patients (BMI 18.5 to 24.9). Exercise capacity in METs, weight, blood pressure, and fasting lipid profile were measured before and after CR. Overall, 131 patients gained weight, 827 had no significant weight change, and 363 lost weight (176 lost 3% to 5% of their baseline weight, 161 lost 5% to 10%, and 26 lost >10%). Exercise capacity, blood pressure, and low-density lipoprotein cholesterol improved in all patients. Class III obese patients had the smallest improvement in peak METs (p <0.001), but the greatest weight loss. Patients who lost >10% of their baseline weight had the greatest improvements in exercise capacity, low-density lipoprotein, and triglycerides. In conclusion, after CR, a minority of patients lost weight. Most patients had no significant weight change and some even gained weight. The greatest loss was seen in class III obese patients. All patient groups showed improvements in exercise capacity and risk factors, regardless of the direction or degree of weight change.
authors.affiliation: Department of Cardiology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.
authors.forename: Pallavi S
authors.initials: PS
authors.lastname: Gomadam
authors.affiliation: Department of Cardiology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Douglas
authors.affiliation: Department of Cardiology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Sacrinty
authors.affiliation: Department of Cardiology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.
authors.forename: Molly M
authors.initials: MM
authors.lastname: Brady
authors.affiliation: Department of Cardiology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina.
authors.forename: Connie C
authors.initials: CC
authors.lastname: Paladenech
authors.affiliation: Department of Cardiology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina. Electronic address: Kcrobins@wakehealth.edu.
authors.forename: Killian C
authors.initials: KC
authors.lastname: Robinson
mesh_terms: D000368:Aged; D001835:Body Weight / Q000502:physiology*; D000072038:Cardiac Rehabilitation; D002318:Cardiovascular Diseases / Q000209:etiology / Q000503:physiopathology; D005081:Exercise Therapy / Q000379:methods*; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009657:North Carolina / Q000453:epidemiology; D009767:Obesity, Morbid / Q000150:complications* / Q000453:epidemiology / Q000534:rehabilitation; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors