title: HPV Vaccine utilization, Alberta 2008/09-2013/14 School year.
abstract: BACKGROUND
  In Canada both bivalent (bHPV) vaccine and quadrivalent HPV vaccine (qHPV) are authorized for use. In Alberta, while both vaccines are available for private purchase, only qHPV is publicly funded for school girls in grades 5 and 9 as of 2013. We describe HPV vaccine uptake in Alberta, by school year, from the start of the publicly funded program in the Fall of 2008 through to August 31(st) 2014 and estimate the cumulative proportion of the female population who were vaccinated by the end of the 2013/14 school year.
  
  
  METHODS
  We used data from the Alberta Ministry of Health Immunization and Adverse Reaction to Immunization repository (publicly funded vaccine), the population-based Pharmaceutical Information Network information systems (privately purchased vaccine) for the period September 1, 2008 to August 31, 2014 and demographic data from the Alberta Health Care Insurance Plan Registry. We estimate vaccine uptake rates and explore them by attributes of person, time, place, vaccine funding, and number of doses received. We estimated the cumulative proportions of the female population (by age group and number of doses received) who had received HPV vaccine by the end of the 2013/14 school year.
  
  
  RESULTS
  Of the 169,259 unique individuals who received one or more doses of HPV vaccine over the period, 98.3% were females, and 83.8% received publicly funded vaccines. Vaccine uptake increased over the period. The cumulative proportion of females aged 9-26 years as of 2013/14 who had received two or more doses of vaccine was 34.3%; for those aged 10-11 years 59.6% and for those aged 14-15 years, 76.0%. For those aged 9-26 years, 31.3% had received three doses of vaccine.
  
  
  CONCLUSIONS
  HPV vaccine uptake rates have increased in Alberta over the study period, most prominently among the age groups targeted by the publicly funded school-girl vaccine program.
authors.affiliation: Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada. xcliu@ucalgary.ca.
authors.forename: Xianfang C
authors.initials: XC
authors.lastname: Liu
authors.affiliation: Epidemiology and Surveillance Team, Alberta Ministry of Health, 23rd fl Telus Plaza NT, 10025 Jasper Avenue, Edmonton, AB, T5J 1S6, Canada. chris.bell@gov.ab.ca.
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Bell
authors.affiliation: Epidemiology and Surveillance Team, Alberta Ministry of Health, 23rd fl Telus Plaza NT, 10025 Jasper Avenue, Edmonton, AB, T5J 1S6, Canada. kimberley.simmonds@gov.ab.ca.
authors.forename: Kimberley A
authors.initials: KA
authors.lastname: Simmonds
authors.affiliation: Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada. mlrussel@ucalgary.ca.
authors.forename: Margaret L
authors.initials: ML
authors.lastname: Russell
authors.affiliation: Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada. larry.svenson@gov.ab.ca.|Epidemiology and Surveillance Team, Alberta Ministry of Health, 23rd fl Telus Plaza NT, 10025 Jasper Avenue, Edmonton, AB, T5J 1S6, Canada. larry.svenson@gov.ab.ca.|School of Public Health, University of Alberta, Edmonton, AB, T6G 1C9, Canada. larry.svenson@gov.ab.ca.
authors.forename: Lawrence W
authors.initials: LW
authors.lastname: Svenson
mesh_terms: D000293:Adolescent; D000328:Adult; D000416:Alberta / Q000453:epidemiology; D002648:Child; D005260:Female; D006801:Humans; D017589:Immunization Programs / Q000191:economics; D008297:Male; D027383:Papillomaviridae / Q000276:immunology; D030361:Papillomavirus Infections / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control* / Q000821:virology; D053918:Papillomavirus Vaccines / Q000008:administration & dosage* / Q000276:immunology; D015397:Program Evaluation; D012574:Schools; D014611:Vaccination; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines