title: Muscle versus Snail: Muscle wins.
abstract: Epithelial-mesenchymal transitions (EMTs) are often governed by the transcription factor Snail and entail the loss of apical junctions from epithelial cells. In this issue, Weng and Wieschaus (2016. J Cell Biol. http://dx.doi.org/10.1083/jcb.201508056) report that actomyosin contractility can strengthen junctions to override Snail-dependent junctional disassembly and postpone EMT during Drosophila melanogaster gastrulation.
authors.affiliation: Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M5S 3G5, Canada.
authors.forename: Sergio
authors.initials: S
authors.lastname: Simoes
authors.affiliation: Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario M5S 3G5, Canada u.tepass@utoronto.ca.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Tepass
mesh_terms: D022005:Adherens Junctions / Q000502:physiology*; D000818:Animals; D029721:Drosophila Proteins / Q000502:physiology*; D058750:Epithelial-Mesenchymal Transition; D005260:Female; D054262:Gastrulation; D008297:Male; D024462:Myosin Type II / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology*
chemical_list: D029721:Drosophila Proteins; D014157:Transcription Factors; D024462:Myosin Type II