title: A histopathological study of prostate lesions in Lagos, Nigeria: A private practice experience.
abstract: BACKGROUND
  Prostatic carcinoma (CaP) is globally the second most frequently diagnosed cancer and the sixth leading cause of cancer death in males. The aim of this study is to determine the pattern of histopathological types of prostatic lesions seen in a private laboratory in Lagos, Nigeria.
  
  
  METHODS
  Histopathological reports of all prostate specimens, which were received and processed by histopathology section of a private laboratory in Lagos, Nigeria, from August 2009 to December 2013 were reviewed.
  
  
  RESULTS
  A total of 304 prostatic tissue specimens were received and processed during the period under review. The youngest patient was 32 years old while the oldest patient was 99 years old with a mean of 67.8 years ± 9.5. The most common diagnosis was benign prostatic hyperplasia (BPH) (62.8%), distantly followed by CaP (29.3%), inadequate samples (6.6%), prostatic intraepithelial neoplasia (1%), and metastasis to the prostate (0.3%). The peak incidence was age group of 60-69 years, closely followed by 70-79 years accounting for 38.2% and 36.2%, respectively. Moderately differentiated CaP (Gleason scores [GSs] 5-7) accounted for 58.1% of the cases while GS 7 was the most common individual score and was seen in 32.3% of the CaP cases.
  
  
  CONCLUSIONS
  In this private practice, BPH is the most common prostate lesion. CaP is relatively high and most of the cases have a high GS that portends high mortality in our population. Efforts should be made to increase awareness so as to reduce the mortality.
authors.affiliation: Department of Pathology, University of Uyo, Uyo, Akwa Ibom State, Nigeria.
authors.forename: Chukwuemeka Charles
authors.initials: CC
authors.lastname: Nwafor
authors.affiliation: Department of Pathology, Me Cure Healthcare Limited, Oshodi, Lagos State, Nigeria.
authors.forename: Olalekan Samuel
authors.initials: OS
authors.lastname: Keshinro
authors.affiliation: Department of Pathology, University of Uyo, Uyo, Akwa Ibom State, Nigeria.
authors.forename: Emmanuel Kunle
authors.initials: EK
authors.lastname: Abudu
keywords: Benign prostatic hyperplasia; private practice; prostatic carcinoma