title: Changes in Peripheral Refraction, Higher-Order Aberrations, and Accommodative Lag With a Radial Refractive Gradient Contact Lens in Young Myopes.
abstract: OBJECTIVE
  To evaluate changes in the peripheral refraction (PR), visual quality, and accommodative lag with a novel soft radial refractive gradient (SRRG) experimental contact lens that produces peripheral myopic defocus.
  
  
  METHODS
  59 myopic right eyes were fitted with the lens. The PR was measured up to 30° in the nasal and temporal horizontal visual fields and compared with values obtained without the lens. The accommodative lag was measured monocularly using the distance-induced condition method at 40 cm, and the higher-order aberrations (HOAs) of the entire eye were obtained for 3- and 5-mm pupils by aberrometry. Visual performance was assessed through contrast sensitivity function (CSF).
  
  
  RESULTS
  With the lens, the relative PR became significantly less hyperopic from 30° to 15° temporally and 30° nasally in the M and J0 refractive components (P<0.05). Cylinder foci showed significant myopization from 30° to 15° temporally and 30° to 25° nasally (P<0.05). The HOAs increased significantly, the CSF decreased slightly but reached statistical significance for 6 and 12 cycles per degree (P<0.05), and the accommodative lag decreased significantly with the SRRG lens (P=0.0001). There was a moderate correlation between HOAs and CSF at medium and high spatial frequencies.
  
  
  CONCLUSIONS
  The SRRG lens induced a significant change in PR, particularly in the temporal retina. Tangential and sagittal foci changed significantly in the peripheral nasal and temporal retina. The decreased accommodative lag and increased HOAs particularly in coma-like aberration may positively affect myopia control. A longitudinal study is needed to confirm this potential.
authors.affiliation: Department of Optometry (J.P.), Centro Médico Teknon, Barcelona, Spain; Department of Optics and Optometry (S.T., J.A., L.Q.), Polytechnic University of Catalonia-Barcelona Tech, Spain; and Clinical & Experimental Optometry Research Lab (CEORLab) (J.M.G.-M., M.F.-R.), Department and Center of Physics, University of Minho, Braga, Portugal.
authors.forename: Jaume
authors.initials: J
authors.lastname: Pauné
authors.forename: Solène
authors.initials: S
authors.lastname: Thivent
authors.forename: Jesús
authors.initials: J
authors.lastname: Armengol
authors.forename: Lluisa
authors.initials: L
authors.lastname: Quevedo
authors.forename: Miguel
authors.initials: M
authors.lastname: Faria-Ribeiro
authors.forename: José M
authors.initials: JM
authors.lastname: González-Méijome
mesh_terms: D000065:Accommodation, Ocular / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D003263:Contact Lenses, Hydrophilic; D015350:Contrast Sensitivity / Q000502:physiology; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000534:rehabilitation*; D012029:Refraction, Ocular / Q000502:physiology*; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology*; D055815:Young Adult