title: The Role of Inclusion Binding Contributions for β-Cyclodextrin Polymers Cross-Linked with Divinyl Sulfone?--A Comment on Morales-Sanfrutos et al. Entitled "Divinyl Sulfone Cross-Linked Cyclodextrin-Based Polymeric Materials: Synthesis and Applications as Sorbents and Encapsulating Agents", Molecules, 2015, 20, 3565-3581.
abstract: This commentary reports on a recent scientific study reported in this journal (cf. Molecules 2015, 20(3), 3565-3581). Some key scientific issues that require further explanation and clarification in the former article are as follows: (i) the relationship between the inclusion site accessibility and the level of cross-linking employed are brought into question for the case of α-CD and β-CD cross-linked adsorbent materials; (ii) the binding affinity of the CD/guest complexes were not related to the isotherm parameters for the CD-polymer/guest systems; (iii) the limited molecular level structural characterization of the cross-linked polymer materials; and (iv) the interpretation of the adsorption isotherm results by the authors.
authors.affiliation: Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C9, Canada. lee.wilson@usask.ca.
authors.forename: Lee D
authors.initials: LD
authors.lastname: Wilson
authors.affiliation: Department of Chemistry, College of Arts and Science, University of Saskatchewan, 110 Science Place, Saskatoon, SK S7N 5C9, Canada. mom133@mail.usask.ca.
authors.forename: Mohamed H
authors.initials: MH
authors.lastname: Mohamed
authors.affiliation: Environmental Systems Engineering, Faculty of Engineering and Applied Science, University of Regina, 3737 Wascana Parkway, Regina, SK S4S0A2, Canada. Dena.McMartin@uregina.ca.
authors.forename: Dena W
authors.initials: DW
authors.lastname: McMartin
mesh_terms: D003432:Cross-Linking Reagents / Q000494:pharmacology*; D003505:Cyclodextrins / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D013213:Starch / Q000737:chemistry*; D013450:Sulfones / Q000737:chemistry*
chemical_list: D003432:Cross-Linking Reagents; D003505:Cyclodextrins; D011108:Polymers; D013450:Sulfones; D013213:Starch
keywords: adsorption; cross-linking; divinyl sulfone; inclusion binding; phenolphthalein; polymer; β-cyclodextrin