title: The base-promoted synthesis of multisubstituted benzo[b][1,4]oxazepines.
abstract: A novel protocol to synthesize multisubstituted benzo[b][1,4]oxazepines from N-(2-haloaryl)enaminones has been developed. In this procedure, only 2 equiv. of Cs2CO3 was required. A variety of polysubstituted benzo[b][1,4]oxazepine derivatives were provided in up to 95% yield for 27 examples.
authors.affiliation: Key Laboratory of Xiamen Marine and Gene Drugs, Institutes of Molecular Medicine and School of Biomedical Sciences, Huaqiao University & Engineering Research Center of Molecular Medicine, Ministry of Education, Xiamen 361021, China. cuixl@hqu.edu.cn.
authors.forename: Jinhai
authors.initials: J
authors.lastname: Shen
authors.forename: Lulu
authors.initials: L
authors.lastname: Xue
authors.forename: Xing
authors.initials: X
authors.lastname: Lin
authors.forename: Guolin
authors.initials: G
authors.lastname: Cheng
authors.forename: Xiuling
authors.initials: X
authors.lastname: Cui