title: Sex-Related Difference in Muscle Deoxygenation Responses Between Aerobic Capacity-Matched Elderly Men and Women.
abstract: Muscle O2 dynamics during ramp cycling exercise were compared between aerobic capacity-matched elderly men (n=8, age 65±2 years) and women (n=8, age 66±3 years). Muscle O2 saturation (SmO2) and relative change in deoxygenated (Δdeoxy-Hb) and total hemoglobin concentration (Δtotal-Hb) were monitored continuously during exercise in the vastus lateralis (VL) and gastrocnemius medialis (GM) by near infrared spatial resolved spectroscopy. SmO2 was significantly higher during exercise in women than in men in VL, but not in GM. In VL, Δdeoxy-Hb and Δtotal-Hb were significantly higher in men than in women, especially during high intensity exercise. However, no significant difference was observed in Δdeoxy-Hb or Δtotal-Hb in GM. Sex-related differences in muscle deoxygenation response may be heterogeneous among leg muscles in elderly subjects.
authors.affiliation: Faculty of Sport Sciences, Waseda University, 2-579-15, Mikajima, Tokorozawa, Saitama, 359-1192, Japan. stakagi@aoni.waseda.jp.|Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan. stakagi@aoni.waseda.jp.
authors.forename: Shun
authors.initials: S
authors.lastname: Takagi
authors.affiliation: Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan.
authors.forename: Ryotaro
authors.initials: R
authors.lastname: Kime
authors.affiliation: Department of Electrical and Electronic Engineering, Shizuoka University, Hamamatsu, Shizuoka, Japan.
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Niwayama
authors.affiliation: Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Osada
authors.affiliation: Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Murase
authors.affiliation: Faculty of Sport Sciences, Waseda University, 2-579-15, Mikajima, Tokorozawa, Saitama, 359-1192, Japan.
authors.forename: Shizuo
authors.initials: S
authors.lastname: Sakamoto
authors.affiliation: Department of Sports Medicine for Health Promotion, Tokyo Medical University, Shinjuku, Tokyo, Japan.
authors.forename: Toshihito
authors.initials: T
authors.lastname: Katsumura
mesh_terms: D000368:Aged; D015444:Exercise / Q000502:physiology*; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption; D012727:Sex Characteristics
chemical_list: D006454:Hemoglobins; D010100:Oxygen
keywords: Aging; Cycling exercise; Muscle oxygen dynamics; Near infrared spectroscopy; Regional difference