title: [Long-Term Survival with Multidisciplinary Therapy for Rectal NET with Liver Metastases--A Case Report].
abstract: We report a case of a 71-year-old man with liver metastases from a rectal neuroendocrine tumor(NET). The patient's chief complaint was melena. He was diagnosed with rectal carcinoma with liver metastases during his initial visit. Therefore, we started UFT/LV as first-line chemotherapy. After 2 courses, the patient's disease had progressed, so the treatment was changed to S-1 as second-line chemotherapy. The patient showed a partial response. In February 2010, we performed an anterior resection, and in April 2010 we performed a posterior segment and S2/8 partial hepatectomy. Histopathological examination showed rectal NET with liver metastases. In December 2011, multiple liver metastases were found, and multimodal treatment including TACE, RFA and somatostatin analogues was selected to treat the recurrent tumor. The patient survived for 10 years after his first visit and for 3 years and 6 months after the recurrence. Multidisciplinary therapy was effective for treating rectal NET with liver metastases.
authors.affiliation: Dept. of Surgery, Toyonaka Municipal Hospital.
authors.forename: Go
authors.initials: G
authors.lastname: Shinke
authors.forename: Takehiro
authors.initials: T
authors.lastname: Noda
authors.forename: Hisanori
authors.initials: H
authors.lastname: Hatano
authors.forename: Masashi
authors.initials: M
authors.lastname: Hirota
authors.forename: Akihiro
authors.initials: A
authors.lastname: Takata
authors.forename: Kazuteru
authors.initials: K
authors.lastname: Oshima
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Tanida
authors.forename: Takamichi
authors.initials: T
authors.lastname: Komori
authors.forename: Shunji
authors.initials: S
authors.lastname: Morita
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imamura
authors.forename: Takashi
authors.initials: T
authors.lastname: Iwazawa
authors.forename: Kenzo
authors.initials: K
authors.lastname: Akagi
authors.forename: Keizo
authors.initials: K
authors.lastname: Dono
mesh_terms: D000368:Aged; D017115:Catheter Ablation; D003082:Colectomy; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy*; D008297:Male; D018358:Neuroendocrine Tumors / Q000556:secondary / Q000628:therapy*; D011379:Prognosis; D012004:Rectal Neoplasms / Q000473:pathology / Q000628:therapy*; D013004:Somatostatin / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D013004:Somatostatin