title: Microcystbiopterins A-E, five O-methylated biopterin glycosides from two Microcystis spp. bloom biomasses.
abstract: Five previously undescribed biopterin glycosides, microcystbiopterin A-E, were isolated from the extracts of two bloom materials of Microcystis spp. collected from a fishpond (IL-337) and Lake Kinneret (IL-347), Israel. The structure of the pterins was established by interpretation of their UV, CD, 1D and 2D NMR spectra and HR mass measurements. Microcystbiopterin D is the first heptose containing pterin glycoside to be reported in the literature. Their antimicrobial and cytotoxic properties were evaluated but all were found not active in both assays.
authors.affiliation: Raymond and Beverly Sackler School of Chemistry and Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.
authors.forename: Marina
authors.initials: M
authors.lastname: Lifshits
authors.affiliation: Raymond and Beverly Sackler School of Chemistry and Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.
authors.forename: Dimitri
authors.initials: D
authors.lastname: Kovalerchik
authors.affiliation: Raymond and Beverly Sackler School of Chemistry and Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv 69978, Israel. Electronic address: carmeli@post.tau.ac.il.
authors.forename: Shmuel
authors.initials: S
authors.lastname: Carmeli
mesh_terms: D018533:Biomass; D001708:Biopterins / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007557:Israel; D046931:Microcystis / Q000737:chemistry*; D015394:Molecular Structure; D061005:Ponds
chemical_list: D006027:Glycosides; C000610691:microcystbiopterin D; D001708:Biopterins
keywords: Biopterin glycosides; Cyanobacteria; Microcystbiopterin A; Microcystbiopterin B; Microcystbiopterin C; Microcystbiopterin D; Microcystbiopterin E; Microcystbiopterins A–E; Microcystis spp. (Microcystaceae); UV-A