title: Epidemiology and Prevalence of Abnormal Results for Anal Cytology Screening in HIV-Infected Young Men Who Have Sex with Men.
abstract: OBJECTIVE
  To determine the prevalence and risk factors for dysplasia in an urban population of HIV-infected young men who have sex with men (YMSM) and to determine the adherence to guidelines for anal cytology screening.
  
  
  METHODS
  The electronic medical record was utilized to collect pre-existing demographic information, medical history, laboratory data, and anal cytology results.
  
  
  RESULTS
  Among 60 subjects (mean age 21.2 years) at their first diagnostic anal cytology, 32 (53.3%) had an anal cytological abnormality and 28 (46.7%) had normal anal cytology. The abnormal results were as follows: 21 (65.6%) had atypical squamous cells of undetermined significance (ASCUS), one (3.1%) had atypical squamous cells and high-grade squamous intraepithelial lesion could not be excluded, nine (28.1%) had low-grade squamous intraepithelial lesion, and one (3.1%) had high-grade squamous intraepithelial lesion. In univariate analysis, abnormal anal cytology was not associated with any of the identified risk factors. The proportion of YMSM at the HIV Specialized Care Center who had an anal cytology screen rose from 32.3% (10/31) in 2008, the first full year of anal cytology screening at this clinic, to 81.4% (35/43) in 2012.
  
  
  CONCLUSIONS
  The prevalence of abnormal anal cytology in this YMSM population is similar to the prevalence in other, primarily adult men who have sex with men, HIV-infected populations. Further studies are necessary to determine risk factors and outcomes of abnormal test results in HIV-infected YMSM populations.
authors.affiliation: 1 Columbia University Medical Center - College of Physicians & Surgeons , New York, New York.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Coromilas
authors.affiliation: 2 Department of Pediatrics, Columbia University Medical Center , New York, New York.
authors.forename: Ava
authors.initials: A
authors.lastname: Brozovich
authors.affiliation: 3 NewYork-Presbyterian Hospital , New York, New York.
authors.forename: John
authors.initials: J
authors.lastname: Nelson
authors.affiliation: 2 Department of Pediatrics, Columbia University Medical Center , New York, New York.
authors.forename: Natalie
authors.initials: N
authors.lastname: Neu
keywords: HPV; YMSM; anal cytology