title: Natural Antimicrobials ε-Poly-L-lysine and Nisin A for Control of Oral Microflora.
abstract: The present study aims to examine the efficacy of the natural antimicrobial ε-poly-L-lysine against Streptococcus mutans and against total aerobic oral microflora, alone and in combination with the natural antimicrobial peptide nisin. In in vitro studies, natural antimicrobials nisin A and ε-poly-L-lysine synergized in their action against S. mutans, leading to the microorganism's full inhibition, while having a less inhibitory effect on total aerobic oral microbiota.
authors.affiliation: Department of Food Science, Rutgers, The State University of New Jersey, 65 Dudley Road, New Brunswick, NJ, 08901, USA.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Badaoui Najjar
authors.affiliation: Department of Food Science, Rutgers, The State University of New Jersey, 65 Dudley Road, New Brunswick, NJ, 08901, USA.
authors.forename: Dimitri
authors.initials: D
authors.lastname: Kashtanov
authors.affiliation: Department of Food Science, Rutgers, The State University of New Jersey, 65 Dudley Road, New Brunswick, NJ, 08901, USA. tchikindas@aesop.rutgers.edu.
authors.forename: Michael L
authors.initials: ML
authors.lastname: Chikindas
keywords: Antimicrobial; Nisin; Oral microflora; Poly-lysine; Synergy