title: Abdominal pain-related functional gastrointestinal disorders based on Rome III criteria in a pediatric gastroenterology clinic.
abstract: BACKGROUND
  Functional gastrointestinal disorders (FGIDs) entail several distinct conditions that collectively account for a sizeable proportion of patients complaining of abdominal pain. Physicians' awareness is fundamental to avoid unnecessary evaluations and to alleviate stress-related problems. This study aimed to assess the relative frequencies of FGIDs and related categories in a selected Iranian population.
  
  
  METHODS
  We conducted this cross-sectional study in a gastroenterology clinic of a tertiary care pediatric hospital in Iran. Children and adolescents between the age of 4 and 18 years referred to the clinic from October 2011 to February 2013 were enrolled if they were diagnosed with FGID according to the Rome III criteria. A structured questionnaire was used to collect data on demographic characteristics, pain location, duration and frequency, associated symptoms, and pertinent family history. We used descriptive analyses to show mean (±SD) and relative frequencies of categories of FGIDs.
  
  
  RESULTS
  We diagnosed 183 (114 female) with FGIDs out of 1307 children and adolescents who were visited in the clinic. There was history of psychiatric disorders in 42 (22.9%) participants, and migraine headaches and gastrointestinal disorders were at least in one of the parents in 21 (11.5%) and 64 (34.9%) participants, respectively. We defined 84 (46%) patients under Irritable Bowel Syndrome (IBS) category, 38 (21%) under Abdominal Migraine, 26 (14%) under Functional Abdominal Pain, 21 (11%) under Functional Dyspepsia, and 7 (4%) under Functional Abdominal Pain Syndrome. Seven children (4%) had no defining feature for FGID categories and therefore labeled as unclassified.
  
  
  CONCLUSIONS
  FGID was a prevalent diagnosis among children and adolescents with abdominal pain. IBS was the largest category. Only a minority were unclassifiable under the Rome III criteria, indicating improved differentiation characteristics of Rome III criteria compared to the Rome II version.
authors.affiliation: MD, Associate Professor, Pediatric Gastroenterology division Ali-Asghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran. talachian.e@iums.ac.ir.
authors.forename: Elham
authors.initials: E
authors.lastname: Talachian
authors.affiliation: MD, Associate Professor, Emergency Department Hazrat-e-Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. bidari.a@iums.ac.ir.
authors.forename: Ali
authors.initials: A
authors.lastname: Bidari
authors.affiliation: Pediatric Specialist. h.zahmatkesh67@yahoo.com.
authors.forename: Hamed
authors.initials: H
authors.lastname: Zahmatkesh
keywords: Abdominal pain; Children; Functional gastrointestinal disorders (FGIDs); Iran; Rome criteria