title: Photoresponsive self-healing supramolecular hydrogels for light-induced release of DNA and doxorubicin.
abstract: An azobenzene-containing cyclic dipeptide PAP-DKP-Lys is a photoresponsive low-MW hydrogelator. The gelation process can be triggered with temperature, pH, light, and ionic strength. The resulting self-healing gels can encapsulate dsDNA or an anticancer drug doxorubicin, and release them in a light-dependent manner.
authors.affiliation: Institut für Organische Chemie, Karlsruher Institut für Technologie, Fritz-Haber-Weg 6, D-76131 Karlsruhe, Germany and Institut für Toxikologie und Genetik, Karlsruher Institut für Technologie, Herman-von-Helmholtz Platz 1, D-76344 Eggenstein-Leopoldshafen, Germany. pianowski@kit.edu.
authors.forename: Zbigniew L
authors.initials: ZL
authors.lastname: Pianowski
authors.affiliation: Institut für Organische Chemie, Karlsruher Institut für Technologie, Fritz-Haber-Weg 6, D-76131 Karlsruhe, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Karcher
authors.affiliation: Institut für Organische Chemie, Karlsruher Institut für Technologie, Fritz-Haber-Weg 6, D-76131 Karlsruhe, Germany.
authors.forename: Knut
authors.initials: K
authors.lastname: Schneider
mesh_terms: D004247:DNA / Q000737:chemistry*; D004317:Doxorubicin / Q000737:chemistry*; D020100:Hydrogels / Q000737:chemistry*; D008027:Light; D008855:Microscopy, Electron, Scanning; D009994:Osmolar Concentration; D055668:Photochemical Processes
chemical_list: D020100:Hydrogels; D004317:Doxorubicin; D004247:DNA