title: [Measurement of mass fraction of Sanjie Zhentong capsules with near infrared reflectance spectroscopy].
abstract: Sanjie Zhentong capsules were scanned by using a near infrared spectra probe with different drug mass fraction and the spectral information of capsule shells and contents in it were obtained. Then partial least squares (PLS) models were developed for the prediction of mass fraction of Fritillariae Thunbergii Bulbus and Resine draconis in Sanjie Zhentong capsules. The correlation coefficient (r9c)) and root mean standard error( RMSEC) of 0.949 5, 0.958 2 and 4.742 4, 4.135 7. The models obtained correlation coefficient (r(v)) of 0.919 2, 0.936 7 and root mean square error (RMSECV) of 6.158 9, 5.037 3 respectively in the training set. The paired T test analysis of statistics showed that there were no significant difference between predictive values and measure values. The established models reflected a strong prediction performance and can meet the needs of the production.
authors.forename: Guang-ren
authors.initials: GR
authors.lastname: Zhang
authors.forename: Yun
authors.initials: Y
authors.lastname: Wu
authors.forename: Rui-ting
authors.initials: RT
authors.lastname: Jin
authors.forename: Qin
authors.initials: Q
authors.lastname: Wan
authors.forename: Jin-feng
authors.initials: JF
authors.lastname: Wu
authors.forename: Xiao-qian
authors.initials: XQ
authors.lastname: Xu
authors.forename: Wei
authors.initials: W
authors.lastname: Xiao
mesh_terms: D002214:Capsules / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D016018:Least-Squares Analysis; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal