title: Zika virus infection in a traveller returning from the Maldives, June 2015.
abstract: We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infection and the circulation of ZIKV in areas outside its currently known distribution range.
authors.affiliation: Department of Virology, Medicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
authors.forename: Essi Marjana
authors.initials: EM
authors.lastname: Korhonen
authors.forename: Eili
authors.initials: E
authors.lastname: Huhtamo
authors.forename: Teemu
authors.initials: T
authors.lastname: Smura
authors.forename: Hannimari
authors.initials: H
authors.lastname: Kallio-Kokko
authors.forename: Markku
authors.initials: M
authors.lastname: Raassina
authors.forename: Olli
authors.initials: O
authors.lastname: Vapalahti
mesh_terms: D000328:Adult; D003715:Dengue / Q000175:diagnosis*; D003716:Dengue Virus / Q000302:isolation & purification; D005076:Exanthema / Q000209:etiology; D005334:Fever / Q000175:diagnosis / Q000209:etiology / Q000821:virology; D005387:Finland; D006801:Humans; D007195:Indian Ocean Islands; D008297:Male; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017423:Sequence Analysis, RNA; D014195:Travel; D000071244:Zika Virus / Q000235:genetics / Q000302:isolation & purification*; D000071243:Zika Virus Infection / Q000175:diagnosis* / Q000652:urine / Q000821:virology
chemical_list: D012367:RNA, Viral
keywords: Zika virus; emerging infectious diseases; flavivirus; mosquito-borne; traveller