title: A Matter of Perspective: Comparison of the Characteristics of Persons with HIV Infection in the United States from the HIV Outpatient Study, Medical Monitoring Project, and National HIV Surveillance System.
abstract: Comparative analyses of the characteristics of persons living with HIV infection (PLWH) in the United States (US) captured in surveillance and other observational databases are few. To explore potential joint data use to guide HIV treatment and prevention in the US, we examined three CDC-funded data sources in 2012: the HIV Outpatient Study (HOPS), a multisite longitudinal cohort; the Medical Monitoring Project (MMP), a probability sample of PLWH receiving medical care; and the National HIV Surveillance System (NHSS), a surveillance system of all PLWH. Overall, data from 1,697 HOPS, 4,901 MMP, and 865,102 NHSS PLWH were analyzed. Compared with the MMP population, HOPS participants were more likely to be older, non-Hispanic/Latino white, not using injection drugs, insured, diagnosed with HIV before 2009, prescribed antiretroviral therapy, and to have most recent CD4+ T-lymphocyte cell count ≥500 cells/mm3 and most recent viral load test<2 00 copies/mL. The MMP population was demographically similar to all PLWH in NHSS, except it tended to be slightly older, HIV diagnosed more recently, and to have AIDS. Our comparative results provide an essential first step for combined epidemiologic data analyses to inform HIV care and prevention for PLWH in the US.
authors.affiliation: Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Kate
authors.initials: K
authors.lastname: Buchacz
authors.affiliation: Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Emma L
authors.initials: EL
authors.lastname: Frazier
authors.affiliation: Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: H Irene
authors.initials: HI
authors.lastname: Hall
authors.affiliation: Cerner Corporation, Kansas City, MO, USA.
authors.forename: Rachel
authors.initials: R
authors.lastname: Hart
authors.affiliation: Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Ping
authors.initials: P
authors.lastname: Huang
authors.affiliation: Cerner Corporation, Kansas City, MO, USA.
authors.forename: Dana
authors.initials: D
authors.lastname: Franklin
authors.affiliation: Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Hu
authors.affiliation: Northwestern University, Chicago, IL, USA.
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Palella
authors.affiliation: Northwestern University, Chicago, IL, USA.
authors.forename: Joan S
authors.initials: JS
authors.lastname: Chmiel
authors.affiliation: University of Illinois, Chicago, IL, USA.
authors.forename: Richard M
authors.initials: RM
authors.lastname: Novak
authors.affiliation: Cerner Corporation, Kansas City, MO, USA.
authors.forename: Kathy
authors.initials: K
authors.lastname: Wood
authors.affiliation: Infectious Disease Research Institute, Tampa, FL, USA.
authors.forename: Bienvenido
authors.initials: B
authors.lastname: Yangco
authors.affiliation: Cerner Corporation, Kansas City, MO, USA.
authors.forename: Carl
authors.initials: C
authors.lastname: Armon
authors.affiliation: Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: John T
authors.initials: JT
authors.lastname: Brooks
authors.affiliation: Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Jacek
authors.initials: J
authors.lastname: Skarbinski
keywords: AIDS; HIV; United States.; cohort; epidemiology; observational study; surveillance