title: Engineering of the epigenome: synthetic biology to define functional causality and develop innovative therapies.
authors.affiliation: Laboratory for Epigenetics & Environment, Centre National de Génotypage, CEA-Institut de Génomique, 2 rue Gaston Crémieux, 91000 Evry, France.
authors.forename: Jörg
authors.initials: J
authors.lastname: Tost
mesh_terms: D055808:Drug Discovery; D044127:Epigenesis, Genetic; D057890:Epigenomics / Q000379:methods; D005786:Gene Expression Regulation; D005818:Genetic Engineering / Q000379:methods; D006801:Humans
keywords: CRISPR/Cas9; DNMT; KRAB; LSD1; TALEs; TET; artificial transcription factors; epigenome editing; synthetic biology; zinc fingers