title: Comparison of 1000-Centistoke versus 5000-Centistoke Silicone Oil in Complex Retinal Detachment Surgery.
abstract: OBJECTIVE
  To compare the efficacy and complications of using 1000-centistoke versus 5000-centistoke silicone oil for complex retinal detachment repair.
  
  
  METHODS
  Case series.
  
  
  METHODS
  LRBT Tertiary Eye Hospital, Karachi, from January 2007 to June 2013.
  
  
  METHODS
  Eighty-five eyes (85 patients) presenting with superior rhegmatogenous retinal detachments associated with PVR grades B and C (involving not more than 3 clock hours) were randomized to either 1000 centistokes (n=44) or 5000 centistokes (n=41) silicone oil group. All patients underwent 23-gauge pars plana vitrectomy surgery with silicone oil intraocular tamponade. Patient data was analysed at 18 months post-operatively. IBM SPSS 21 was used for data analysis.
  
  
  RESULTS
  There were 52 male and 33 female patients aged between 22 and 70 years (45.2 ±16.2). After the first surgery, successful reattachment of the retina was achieved in 67 eyes (78.8%); of which 35 eyes were in 1000-centistoke and 32 eyes in 5000-centistoke groups. Mean pre-operative Best Corrected Visual Acuity (BCVA) was 1.63 ±0.54 which was improved to a mean post-operative BCVAof 1.46 ±0.78 (1.42 ±0.74 in 1000-centistoke group; 1.49 ±0.78 in 5000 centistoke group). The 1000-centistoke group had a significantly higher frequency of oil emulsification which necessitated early removal of silicone oil. There were 66 eyes (77%) with at least one complication (34 eyes in 1000-centistoke group; 32 eyes in 5000-centistoke group) including cataract, corneal abnormalities, raised IOP, hypotony, vitreous haemorrhage and retinal redetachment.
  
  
  CONCLUSIONS
  Although visual and anatomical outcomes were comparable between the two groups, the 1000-centistoke silicone oil group developed early oil emulsification necessitating its early removal.
authors.affiliation: Department of Ophthalmology, LRBT Free Base Eye Hospital, Korangi, Karachi.
authors.forename: Shakir
authors.initials: S
authors.lastname: Zafar
authors.affiliation: Department of Ophthalmology, LRBT Free Base Eye Hospital, Korangi, Karachi.
authors.forename: Munira
authors.initials: M
authors.lastname: Shakir
authors.affiliation: Department of Ophthalmology, LRBT Free Base Eye Hospital, Korangi, Karachi.
authors.forename: Syed Asaad
authors.initials: SA
authors.lastname: Mahmood
authors.affiliation: Department of Ophthalmology, LRBT Free Base Eye Hospital, Korangi, Karachi.
authors.forename: Saima
authors.initials: S
authors.lastname: Amin
authors.affiliation: Department of Ophthalmology, LRBT Free Base Eye Hospital, Korangi, Karachi.
authors.forename: Zafar
authors.initials: Z
authors.lastname: Iqbal
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery*; D012827:Silicone Oils / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy; D018630:Vitreoretinopathy, Proliferative / Q000150:complications* / Q000601:surgery; D014822:Vitreous Body; D055815:Young Adult
chemical_list: D012827:Silicone Oils