title: [A Case of Advanced Seminoma in a 79-Year-Old Man Successfully Treated with Etoposide and Cisplatin].
abstract: Testicular tumors are representative solid cancers that occur in young men, and the standard multi-drug combination chemotherapy has been established for metastatic tumors. However, they develop rarely in elderly men over 70 years old, and there are few reports about the information of combination chemotherapy for elderly testicular tumor patients. Here, we present a case in a 79-year-old who had right testicular tumors (seminoma, cT2N3M1a, IGCC classification : good prognosis) safely treated with multi-drug combination chemotherapy. To reduce the risk of side effects, we selected 4 courses of etoposide and cisplatin (EP) to the patient. The patient suffered from febrile neutropenia (FN) and oral mucositis during the first cycle of EP. However, no further episodes of oral mucositis and FN were observed after introduction of oral health care by a dentist. The patient received 4 courses of EP without dose reduction or treatment postponement. There was no evidence of recurrence 6 months after chemotherapy. To our knowledge, the present case is the oldest patient with metastatic testicular treated with combination chemotherapy including cisplatin.
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Masanobu
authors.initials: M
authors.lastname: Shiga
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Koji
authors.initials: K
authors.lastname: Kawai
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Kousuke
authors.initials: K
authors.lastname: Kojyo
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kurobe
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Daishi
authors.initials: D
authors.lastname: Ichioka
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Yoshino
authors.affiliation: The Department of Urology, Hitachi General Hospital.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ikeda
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kojima
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Akira
authors.initials: A
authors.lastname: Joraku
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Suetomi
authors.affiliation: The Department of Urology, Hitachi General Hospital.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Tsutsumi
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Jun
authors.initials: J
authors.lastname: Miyazaki
authors.affiliation: The Department of Urology, Doctoral Program in Clinical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nishiyama
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use; D005047:Etoposide / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D018239:Seminoma / Q000188:drug therapy*; D013736:Testicular Neoplasms / Q000188:drug therapy*
chemical_list: D005047:Etoposide; D002945:Cisplatin