title: Temporal trends in the prevalence of asthma and rhinoconjunctivitis in adolescents.
abstract: OBJECTIVE
  To analyze the temporal trend of asthma and rhinoconjunctivitis prevalences as well as their symptoms in adolescents.
  
  
  METHODS
  Two cross-sectional studies were conducted using the same methodology and questionnaire as was used for adolescents aged 12 to 14 years in the Brazilian city of Florianopolis, SC, Southern Brazil. Based on the international protocol of the International Study of Asthma and Allergies in Childhood (ISAAC) study, adolescents were evaluated in 2001 and 3,150 in 2012. The schools included in this study were the same as in the 2001 study. These schools were randomly selected after stratification by network (public and private) and geographic location. The total average percentage variation was estimated for the prevalence of asthma and rhinoconjunctivitis and their symptoms.
  
  
  RESULTS
  The prevalence of reported asthma was 10.9% in 2001 and 14.8% in 2012, with an average variation of 2.8% in the period. The highest average variation in the period was observed among female adolescents (4.1%). In parallel a significant increase occurred in reported physician-diagnosed asthma, 7.3% in 2001 and 11,1% in 2012, with an annual variation of 4.5%. The largest increases in reported physician-diagnosed asthma were seen in female (5.9%) and male (4.5%) public school pupils. In addition, a significant increase in reported rhinoconjunctivitis occurred, with the average variation in the period being 5.2%. Reports of severe asthma symptoms remained unchanged during the period, while the annual variation for reported current wheezing (-1.3%) and wheezing during exercise (-1.2%) decreased.
  
  
  CONCLUSIONS
  The results showed a significant increase in the annual average variation for asthma and rhinoconjunctivitis prevalence during the 2001 to 2012 period.
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Fernanda Agapito Pássaro
authors.initials: FA
authors.lastname: Wilmer
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Rosemeri
authors.initials: R
authors.lastname: Maurici
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Carlos Alberto Kuntz
authors.initials: CA
authors.lastname: Nazário
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Kahio César Kuntz
authors.initials: KC
authors.lastname: Nazário
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Paula Fernanda Agapito
authors.initials: PF
authors.lastname: Pássaro
authors.affiliation: Departamento de Clínica Médica, Faculdade de Medicina, Universidade do Sul de Santa Catarina, Palhoça, SC, Brasil.
authors.forename: Helena Elisa
authors.initials: HE
authors.lastname: Piazza
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Rennan Almir
authors.initials: RA
authors.lastname: Bertoldi
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Emílio
authors.initials: E
authors.lastname: Pizzichini
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Márcia Margaret Menezes
authors.initials: MM
authors.lastname: Pizzichini
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D003233:Conjunctivitis, Allergic / Q000175:diagnosis / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D059026:Diagnostic Self Evaluation; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D065631:Rhinitis, Allergic / Q000175:diagnosis / Q000453:epidemiology*; D012574:Schools / Q000706:statistics & numerical data; D012737:Sex Factors; D011795:Surveys and Questionnaires