title: Bone Disease in Myeloma: The Claws of CRAB.
abstract: A dynamic approach to use bisphosphonates according to biomarkers of bone metabolism is presented in the Z-MARK study by Raje and colleagues. This is a major step forward toward a rational approach to bisphosphonate usage.
authors.affiliation: Mayo Clinic in Arizona, Scottsdale, Arizona. fonseca.rafael@mayo.edu.
authors.forename: Rafael
authors.initials: R
authors.lastname: Fonseca
authors.affiliation: Mayo Clinic in Arizona, Scottsdale, Arizona.
authors.forename: Tania
authors.initials: T
authors.lastname: Jain
mesh_terms: D000818:Animals; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D001847:Bone Diseases / Q000188:drug therapy; D004164:Diphosphonates / Q000627:therapeutic use*; D006724:Hoof and Claw; D006801:Humans; D009101:Multiple Myeloma / Q000188:drug therapy
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates