title: Protein corona: Opportunities and challenges.
abstract: In contact with biological fluids diverse type of biomolecules (e.g., proteins) adsorb onto nanoparticles forming protein corona. Surface properties of the coated nanoparticles, in terms of type and amount of associated proteins, dictate their interactions with biological systems and thus biological fate, therapeutic efficiency and toxicity. In this perspective, we will focus on the recent advances and pitfalls in the protein corona field.
authors.affiliation: Department of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, USA.
authors.forename: Saeid
authors.initials: S
authors.lastname: Zanganeh
authors.affiliation: Department of Radiology, Molecular Imaging Program at Stanford, Stanford University, CA, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Spitler
authors.affiliation: Department of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Erfanzadeh
authors.affiliation: Department of Pharmaceutics & Pharmaceutical Technology Faculty of Pharmacy, the University of Jordan, Amman 11942, Jordan.
authors.forename: Alaaldin M
authors.initials: AM
authors.lastname: Alkilany
authors.affiliation: Department of Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: mahmoudi-m@tums.ac.ir.
authors.forename: Morteza
authors.initials: M
authors.lastname: Mahmoudi
mesh_terms: D000818:Animals; D001692:Biological Transport; D065546:Drug Liberation; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry; D000066970:Protein Corona / Q000737:chemistry
chemical_list: D000066970:Protein Corona
keywords: Nanoparticles; Nanotoxicology; Protein corona; Targeting