title: A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab.
abstract: A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI plus bevacizumab chemotherapy as salvage chemotherapy. Stability was achieved after eight cycles of FOLFIRI plus bevacizumab therapy. We conducted a biopsy of the metastatic tumor, and the pathology of the biopsy tissue was partially necrotic. To our knowledge, this case represents the first report of a metastatic urachal carcinoma treated with FOLFIRI plus bevacizumab.
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Kanamaru
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Taro
authors.initials: T
authors.lastname: Iguchi
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Nao
authors.initials: N
authors.lastname: Yukimatsu
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Yasuomi
authors.initials: Y
authors.lastname: Shimizu
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kohyama
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tachibana
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Minoru
authors.initials: M
authors.lastname: Kato
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yamasaki
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Tamada
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno, Osaka 545-8585, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nakatani
keywords: Bevacizumab; Chemotherapy; FOLFIRI; Urachal carcinoma