title: Neurocutaneous disease: Neurocutaneous dysesthesias.
abstract: Dysesthesia is a generic term for a cutaneous symptom--such as pruritus, burning, tingling, stinging, anesthesia, hypoesthesia, tickling, crawling, cold sensation, or even pain--without a primary cutaneous condition in a well-defined location that is often caused by nerve trauma, impingement, or irritation. There are multiple types of dysesthesias depending on the body location and the nerves involved. While location, exact symptoms, and etiologies might vary, the underlying theme is that these conditions are of neurologic origin and have dermatologic consequences. For many of these conditions, the symptoms are localized to the skin, and patients frequently present to the dermatologist; it is important for dermatologists to be knowledgeable about these symptoms and their underlying causes. In part II of this continuing medical education review, the primary diagnoses associated with underlying cutaneous dysesthesias will be explored, including scalp dysesthesia, trigeminal trophic syndrome, meralgia paresthetica, notalgia paresthetica, and brachioradial pruritus. The typical demographics in terms of symptoms, location, and patient populations will be discussed in addition to the specific etiologies, workups, and possible treatment options.
authors.affiliation: Department of Dermatology, University of Missouri, Columbia, Missouri.
authors.forename: Nora K
authors.initials: NK
authors.lastname: Shumway
authors.affiliation: School of Medicine, University of Missouri, Columbia, Missouri.
authors.forename: Emily
authors.initials: E
authors.lastname: Cole
authors.affiliation: Department of Dermatology, University of Missouri, Columbia, Missouri. Electronic address: fernandezk@health.missouri.edu.
authors.forename: Kristen Heins
authors.initials: KH
authors.lastname: Fernandez
mesh_terms: D005148:Facial Dermatoses / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D020428:Femoral Neuropathy; D006801:Humans; D009408:Nerve Compression Syndromes / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D010292:Paresthesia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011537:Pruritus / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012535:Scalp; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D012883:Skin Ulcer / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D013577:Syndrome; D061221:Trigeminal Nerve Injuries / Q000150:complications
keywords: brachioradial pruritus; burning scalp syndrome; dysesthesia; macular amyloidosis; meralgia paresthetica; neurocutaneous; notalgia paresthetica; scalp dysesthesia; trigeminal trophic syndrome