title: Assessment of Egg Yolk Oil Extraction Methods of for ShiZhenKang Oil by Pharmacodynamic Index Evaluation.
abstract: To assess the extraction methods of egg yolk oil in ShiZhenKang (SZK) oil, which is used to treat eczema, a mice model of eczema was established by using 2,4-dinitrochlorobenzene (DNCB). The therapeutic effects of egg yolk oil extracted by different methods from SZK oil on the model of acute eczema in mice were evaluated. The oil yield rate of ethanol extraction is 42.06%. Its egg yolk oil is orange and has a rich, sweet, egg smell. Moreover, the SZK oil prepared from it has a very good therapeutic effect on the model of acute eczema in mice. The alcohol extraction method is the preferable method according to a comprehensive evaluation of each index of seven kinds of methods to extract the egg yolk oil.
authors.affiliation: Hunan Province Engineering Research Center of Bioactive Substance Discovery of Chinese Medicine, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. pingwu@xtu.edu.cn.|School of Chemistry, Xiangtan University, Xiangtan 411105, China. pingwu@xtu.edu.cn.
authors.forename: Ping
authors.initials: P
authors.lastname: Wu
authors.affiliation: Hunan Province Engineering Research Center of Bioactive Substance Discovery of Chinese Medicine, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. panyu1226@gmail.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Pan
authors.affiliation: Hunan Province Engineering Research Center of Bioactive Substance Discovery of Chinese Medicine, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. yanjianye2015@hotmail.com.
authors.forename: Jianye
authors.initials: J
authors.lastname: Yan
authors.affiliation: Hunan Province Engineering Research Center of Bioactive Substance Discovery of Chinese Medicine, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. huangdan2005@hotmail.com.
authors.forename: Dan
authors.initials: D
authors.lastname: Huang
authors.affiliation: Hunan Province Engineering Research Center of Bioactive Substance Discovery of Chinese Medicine, School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. lishunxiang@hotmail.com.
authors.forename: Shunxiang
authors.initials: S
authors.lastname: Li
mesh_terms: D000818:Animals; D005591:Chemical Fractionation / Q000379:methods*; D002645:Chickens; D004195:Disease Models, Animal; D004485:Eczema / Q000188:drug therapy / Q000473:pathology; D004530:Egg Yolk / Q000737:chemistry*; D005260:Female; D008297:Male; D051379:Mice; D009821:Oils / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D009821:Oils
keywords: ShiZhenKang oil; egg yolk oil; extraction methods; pharmacodynamic index