title: Opsoclonus-Myoclonus Syndrome, Neuroblastoma, and Insulin-Dependent Diabetes Mellitus in a Child: A Unique Patient.
abstract: OBJECTIVE
  We present a new and unique association of opsoclonus-myoclonus-ataxia syndrome with neuroblastoma and type 1 diabetes mellitus.
  
  
  METHODS
  This 17-month-old child presented with opsoclonus-myoclonus-ataxia syndrome. Investigations revealed a thoracic neuroblastoma. Eleven days later, she re-presented with diabetic ketoacidosis. The neuroblastoma was resected, and she was given immunotherapy. At 12 months' follow-up, her neurological signs and symptoms have significantly improved, but she continues to be insulin dependent.
  
  
  CONCLUSIONS
  This child expands the clinical spectrum of autoimmune disorders associated with opsoclonus-myoclonus-ataxia syndrome.
authors.affiliation: Department of Neurology, Princess Margaret Hospital, Perth, Western Australia, Australia.
authors.forename: Twinkle
authors.initials: T
authors.lastname: Ghia
authors.affiliation: Department of Neurology, Princess Margaret Hospital, Perth, Western Australia, Australia.
authors.forename: Manoj
authors.initials: M
authors.lastname: Kanhangad
authors.affiliation: Department of Oncology, Princess Margaret Hospital, Perth, Western Australia, Australia.
authors.forename: Angela Jane
authors.initials: AJ
authors.lastname: Alessandri
authors.affiliation: Department of Endocrinology, Princess Margaret Hospital, Perth, Western Australia, Australia.
authors.forename: Glynis
authors.initials: G
authors.lastname: Price
authors.affiliation: Department of Paediatric Surgery, Princess Margaret Hospital, Perth, Western Australia, Australia.
authors.forename: Parshotam
authors.initials: P
authors.lastname: Gera
authors.affiliation: Department of Neurology, Princess Margaret Hospital, Perth, Western Australia, Australia; School of Paediatrics and Child Health, University of Western Australia, Princess Margaret Hospital, Perth, Western Australia, Australia. Electronic address: lakshmi.Nagarajan@health.wa.gov.au.
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Nagarajan
mesh_terms: D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007223:Infant; D009447:Neuroblastoma / Q000175:diagnosis* / Q000601:surgery; D053578:Opsoclonus-Myoclonus Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D013899:Thoracic Neoplasms / Q000175:diagnosis* / Q000601:surgery
keywords: anti-GAD antibodies; neuroblastoma; opsoclonus myoclonus ataxia; type I diabetes mellitus