title: Routine Antibiotic Prophylaxis for Totally Implantable Venous Access Device Placement: Meta-Analysis of 2,154 Patients.
abstract: OBJECTIVE
  To provide a meta-analysis of currently available literature on the topic of antibiotic prophylaxis for totally implanted venous access device (TIVAD) placement.
  
  
  METHODS
  A systematic review of MEDLINE/PubMed was performed to identify studies that met Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria reviewing antibiotic prophylaxis in TIVAD placement. Four studies were identified that met criteria. The analysis included 2,154 patients undergoing TIVAD placement; 360 (16.7%) received antibiotic prophylaxis, and 1,794 (83.3%) received no periprocedural antibiotics.
  
  
  RESULTS
  In the period after TIVAD placement, 27 (1.25%) infections were identified. Of infections, five occurred in the antibiotic prophylaxis group (1.39%), and 22 occurred in the nonprophylaxis group (1.23%) with an odds ratio of 0.84 (CI = 0.29-2.35).
  
  
  CONCLUSIONS
  The odds ratio of infection was 0.85 with antibiotic use but one was contained within the confidence interval suggesting no significant difference in infection rate when antibiotics were used.
authors.affiliation: Department of Radiology, Center for Biomedical Imaging, NYU Langone Medical Center, 660 First Avenue, New York, NY 10016. Electronic address: Evan.Johnson@nyumc.org.
authors.forename: Evan
authors.initials: E
authors.lastname: Johnson
authors.affiliation: Department of Radiology, Center for Biomedical Imaging, NYU Langone Medical Center, 660 First Avenue, New York, NY 10016.
authors.forename: James
authors.initials: J
authors.lastname: Babb
authors.affiliation: Department of Radiology, Center for Biomedical Imaging, NYU Langone Medical Center, 660 First Avenue, New York, NY 10016.
authors.forename: Divya
authors.initials: D
authors.lastname: Sridhar
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000009:adverse effects; D019072:Antibiotic Prophylaxis / Q000009:adverse effects; D055499:Catheter-Related Infections / Q000175:diagnosis / Q000382:microbiology / Q000517:prevention & control*; D006801:Humans; D016017:Odds Ratio; D065840:Protective Factors; D012307:Risk Factors; D016896:Treatment Outcome; D062666:Vascular Access Devices / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents