title: Acute Hemorrhagic Edema of Infancy.
abstract: Acute Hemorrhagic Edema of Infancy is a small vessel leucocytoclastic vasculitis affecting young infants. It is characterized by large, target-like, macular to purpuric plaques predominantly affecting the face, ear lobes and extremities. Non-pitting edema of the distal extremities and low-grade fever may also be present. Extra-cutaneous involvement is very rare. Although the lesions have a dramatic onset in a twenty-four to forty-eight hour period, usually the child has a non-toxic appearance. In most cases there are no changes in laboratory parameters. The cutaneous biopsy reveals an inflammatory perivascular infiltrate. It is a benign and auto-limited disease, with complete resolution within two to three weeks leaving no sequelae in the majority of cases. No recurrences are described. We report a case of a 42-day old girl admitted at our hospital with Acute Hemorrhagic Edema of Infancy.
authors.affiliation: Department of Paediatrics, Hospital Prof. Doutor Fernando Fonseca EPE, Amadora, Portugal. E-Mail: catarinasmgarcia@gmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Serra E Moura Garcia
authors.affiliation: Department of Paediatrics, Hospital Prof. Doutor Fernando Fonseca EPE, Amadora, Portugal.
authors.forename: A
authors.initials: A
authors.lastname: Sokolova
authors.affiliation: Department of Paediatrics, Hospital Prof. Doutor Fernando Fonseca EPE, Amadora, Portugal.
authors.forename: M L
authors.initials: ML
authors.lastname: Torre
authors.affiliation: Department of Dermatology, Hospital CurryCabral, Centro Hospitalar Lisboa Central, Lisbon, Portugal.
authors.forename: C
authors.initials: C
authors.lastname: Amaro
mesh_terms: D000208:Acute Disease; D003937:Diagnosis, Differential; D004487:Edema / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology; D005260:Female; D006801:Humans; D007223:Infant; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology
keywords: Acute Hemorrhagic Edema of Infancy; Henoch-Schönlein Purpura variant; cutaenous purpura; leucocytoclastic vasculitis; small-vessel vasculitis