title: Radiation dose and image quality of 70 kVp functional cardiovascular computed tomography imaging in congenital heart disease.
abstract: BACKGROUND
  The use of cardiac computed tomography (CT) for quantification of ventricular function is limited by relatively high radiation dose.
  
  
  OBJECTIVE
  The goal of this study was to describe the radiation exposure and image quality of 70 kVp functional cardiac CT in patients with congenital heart disease (CHD).
  
  
  METHODS
  A retrospective review of 70 kVp ECG gated functional CT scans using tube current modulation was performed in CHD patients at a single institution. Quantitative and qualitative (assessed by myocardial segment, 1-4; 1 = optimal) image quality was determined. Per segment image quality was compared between thin (1.5 mm) and thick (8 mm) reconstructions and by patient age and size. Scan DLP was used to estimate radiation dose.
  
  
  RESULTS
  72 scans were performed during the time of review (7/2013-6/2015). Median patient age was 19.5 years (8.0, 27.1) and BMI was 20.1 (16.6, 24.5) kg/m(2). Median functional scan DLP was 78.8 (45.5, 98) and unadjusted and adjusted procedural mSv were 1.10 (0.64, 1.37) and 1.13 (0.90, 1.37). Image quality of 1 was achieved in all myocardial segments in >75% of scans. Patients with a weight ≥75 kg were more likely to have a scan achieve optimal image when using thick reconstructions compared to thin (81.3% vs. 43.8%; p = 0.028).
  
  
  CONCLUSIONS
  Imaging of ventricular function with 70 kVp in CHD patients can be done with low radiation doses and provides diagnostic image quality, particularly for patients <75 kg. In larger patients, thicker slice reconstruction improved image quality.
authors.affiliation: Minneapolis Heart Institute and Foundation, USA.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Lesser
authors.affiliation: Minneapolis Heart Institute and Foundation, USA.
authors.forename: Marc C
authors.initials: MC
authors.lastname: Newell
authors.affiliation: Minneapolis Heart Institute and Foundation, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Samara
authors.affiliation: Minneapolis Heart Institute and Foundation, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Gornick
authors.affiliation: Siemens Medical Solutions, USA.
authors.forename: Katharine
authors.initials: K
authors.lastname: Grant
authors.affiliation: Minneapolis Heart Institute and Foundation, USA.
authors.forename: Ross
authors.initials: R
authors.lastname: Garberich
authors.affiliation: Minneapolis Heart Institute and Foundation, USA; The Children's Heart Clinic at the Children's Hospitals and Clinics of Minnesota, USA. Electronic address: khan@chc-pa.org.
authors.forename: B Kelly
authors.initials: BK
authors.lastname: Han
mesh_terms: D000293:Adolescent; D000328:Adult; D001835:Body Weight; D055424:Cardiac-Gated Imaging Techniques; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011829:Radiation Dosage; D000069079:Radiation Exposure; D011857:Radiographic Image Interpretation, Computer-Assisted; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016276:Ventricular Function; D055815:Young Adult
keywords: 70 kVp; Computed tomography imaging; Congenital heart disease; Functional computed tomography; Radiation dose