title: Lung Involvement in Multiple Myeloma - Case Study.
abstract: BACKGROUND
  Mutiple mieloma (MM) cells are rarely found in extramedullary sites. The sites of extramedullary dissemination reported in the literature are spleen, liver, lymph nodes, kidneys, thyroid gland, adrenal gland, ovary, tests, lung, pleura, pericardium, intestinal tract and skin. We report a case in which the myeloma was diagnosed after we discovered the presence of monoclonal plasma cells in the bronchoalveolar lavage fluid (BAL). Matherial and method: a case in which diagnosis was established from bronchoalveolar lavage (BAL) fluid demonstrating the presence of monoclonal plasma cells in Craiova Pneumology Departament.
  
  
  RESULTS
  Analysis of BAL fluid for the presence of plasma cells and for cytoplasmic immunoglobulin DNA provides a noninvasive means of establishing the diagnosis.
  
  
  CONCLUSIONS
  Pulmonary parenchyma is an uncommon site of extramedullary involvement in multiple myeloma. Interstitial lung disease as pulmonary manifestation of multiple myeloma is even rarer; only isolated cases with histological proofs have been reported in the literature.
authors.affiliation: University of Medicine and Pharmacy, Craiova, Pneumology Department.
authors.forename: Mimi
authors.initials: M
authors.lastname: Niţu
authors.affiliation: University of Medicine and Pharmacy, Craiova, Pneumology Department.
authors.forename: Emilia
authors.initials: E
authors.lastname: CriȘan
authors.affiliation: University of Medicine and Pharmacy, Craiova, Pneumology Department.
authors.forename: M
authors.initials: M
authors.lastname: Olteanu
authors.affiliation: "Victor Babeş" Hospital of Infectious Diseases and Pneumology, Craiova.
authors.forename: Cristina
authors.initials: C
authors.lastname: Călăraşu
authors.affiliation: University of Medicine and Pharmacy, Craiova, Pneumology Department.
authors.forename: Mădălina
authors.initials: M
authors.lastname: Olteanu
authors.affiliation: University of Medicine and Pharmacy, Craiova, Pneumology Department.
authors.forename: M R
authors.initials: MR
authors.lastname: Popescu
keywords: lung fibrosis; multiple myeloma; myelomatous pulmonary infiltrate