title: Association between body mass index and outcome in Japanese ischemic stroke patients.
abstract: OBJECTIVE
  An association between body mass index (BMI) and stroke outcome have been reported, but the results are controversial. The aim of the present study was to evaluate whether BMI is associated with ischemic stroke outcome.
  
  
  METHODS
  Consecutive Japanese acute ischemic stroke patients were analyzed. BMI was categorized as underweight (BMI <18.5 kg/m2), normal weight (18.5-24.9 kg/m2) and obese (≥25 kg/m2). BMI and short-term and long-term outcomes were examined. Short-term outcomes were evaluated using the modified Rankin scale score at hospitalization and discharge; modified Rankin scale ≥3 was defined as a poor outcome. Long-term outcomes were evaluated by all-cause mortality. The recurrence rate was also evaluated in each BMI group. Values of P < 0.05 were considered significant.
  
  
  RESULTS
  A total of 1206 acute ischemic stroke patients (760 men; mean age 72.5 years) were analyzed in the present study. There were 111 underweight cases (9.2%), 785 normal weight cases (65.1%) and 310 obese cases (25.7%). The underweight group had a significantly higher rate of poor short and long-term outcomes than the normal weight group. The outcomes of the obese group were not significantly different from those of the normal weight group. Recurrence was not significantly different among the groups.
  
  
  CONCLUSIONS
  Lower BMI might be a predictor of poorer short-term and long-term stroke outcomes. Geriatr Gerontol Int 2017; 17: 369-374.
authors.affiliation: Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Kawase
authors.affiliation: Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan.
authors.forename: Hisanori
authors.initials: H
authors.lastname: Kowa
authors.affiliation: Department of Neurology, Tottori Prefectural Central Hospital, Tottori, Japan.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Suto
authors.affiliation: Department of Neurology, Matsue Red Cross Hospital, Matsue, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Fukuda
authors.affiliation: Department of Neurology, Sanin Rosai Hospital, Yonago, Japan.
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Kusumi
authors.affiliation: Department of Neurology, Tottori Prefectural Central Hospital, Tottori, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakayasu
authors.affiliation: Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Nakashima
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D001835:Body Weight; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D050177:Overweight / Q000175:diagnosis / Q000453:epidemiology; D011237:Predictive Value of Tests; D011379:Prognosis; D012042:Registries; D012189:Retrospective Studies; D018570:Risk Assessment; D020521:Stroke / Q000401:mortality* / Q000503:physiopathology; D016019:Survival Analysis; D013851:Thinness / Q000175:diagnosis / Q000453:epidemiology
keywords: nutrition; obese; rehabilitation; underweight