title: Inferring patterns in mitochondrial DNA sequences through hypercube independent spanning trees.
abstract: Given a graph G, a set of spanning trees rooted at a vertex r of G is said vertex/edge independent if, for each vertex v of G, v≠r, the paths of r to v in any pair of trees are vertex/edge disjoint. Independent spanning trees (ISTs) provide a number of advantages in data broadcasting due to their fault tolerant properties. For this reason, some studies have addressed the issue by providing mechanisms for constructing independent spanning trees efficiently. In this work, we investigate how to construct independent spanning trees on hypercubes, which are generated based upon spanning binomial trees, and how to use them to predict mitochondrial DNA sequence parts through paths on the hypercube. The prediction works both for inferring mitochondrial DNA sequences comprised of six bases as well as infer anomalies that probably should not belong to the mitochondrial DNA standard.
authors.affiliation: Institute of Computing, University of Campinas, Campinas-SP, 13083-852, Brazil. Electronic address: helio@ic.unicamp.br.
authors.forename: Eduardo Sant Ana da
authors.initials: ESAD
authors.lastname: Silva
authors.affiliation: Institute of Computing, University of Campinas, Campinas-SP, 13083-852, Brazil.
authors.forename: Helio
authors.initials: H
authors.lastname: Pedrini
mesh_terms: D000818:Animals; D004272:DNA, Mitochondrial / Q000235:genetics*; D006801:Humans; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software
chemical_list: D004272:DNA, Mitochondrial
keywords: DNA sequence; E-cube; Hypercube; Independent spanning trees; Pattern recognition