title: [Surgical Resection after Chemotherapy for Ampullary Carcinoma with Synchronous Liver Metastasis--Report of a Case].
abstract: A 63-year-old woman presented with abnormalities in liver enzyme levels on laboratory studies, which were detected during a routine medical check-up. She was diagnosed with carcinoma of the ampulla of Vater with a synchronous solitary liver metastasis (S7). She was treated with gemcitabine plus S-1. After 2 courses of the chemotherapy, computed tomography revealed that the primary and metastatic tumors had not changed in size, but new lesions had not appeared. A pylorus-preserving pancreaticoduodenectomy and partial resection of the liver (S7) were performed. She received gemcitabine monotherapy for 1 year and she remains alive and well with no evidence of disease 2 year 10 months after resection.
authors.affiliation: Dept. of Surgery, Nagaoka Red Cross Hospital.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Shimada
authors.forename: Jun
authors.initials: J
authors.lastname: Sakata
authors.forename: Jun
authors.initials: J
authors.lastname: Yamamoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Usui
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Naito
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Tani
authors.forename: Jun
authors.initials: J
authors.lastname: Hasegawa
authors.forename: Naohiro
authors.initials: N
authors.lastname: Shimakage
authors.forename: Takashi
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Wakai
mesh_terms: D014670:Ampulla of Vater / Q000473:pathology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D004338:Drug Combinations; D004379:Duodenal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D016577:Pancreaticoduodenectomy; D005641:Tegafur / Q000008:administration & dosage; D000093542:Gemcitabine
chemical_list: D004338:Drug Combinations; D003841:Deoxycytidine; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000093542:Gemcitabine