title: Effect of Spirulina maxima Supplementation on Calcium, Magnesium, Iron, and Zinc Status in Obese Patients with Treated Hypertension.
abstract: The effects of Spirulina maxima supplementation on calcium, magnesium, iron, and zinc status were studied in a double-blind placebo-controlled trial of 50 obese subjects with treated hypertension, each randomized to receive 2 g of spirulina or a placebo daily for 3 months. At baseline and after treatment, the calcium, magnesium, iron, and zinc concentration in plasma was assessed. It was found that 3 months of S. maxima supplementation resulted in a significant decrease in the iron level in the plasma of obese patients. In conclusion, this is the first clinical study on the influence of spirulina supplementation on mineral status in obese patients with hypertension. Spirulina supplementation affects the iron status of obese Caucasians with well-treated hypertension.
authors.affiliation: Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Wojska Polskiego 31 Str., 60-624, Poznan, Poland. jsulibur@au.poznan.pl.
authors.forename: J
authors.initials: J
authors.lastname: Suliburska
authors.affiliation: Department of Education and Obesity Treatment and Metabolic Disorders, University of Medical Sciences, Poznan, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Szulińska
authors.affiliation: Orenburg State Medical University, Orenburg, Russia.|All-Russian Research Institute of Medicinal and Aromatic Plants (VILAR), Moscow, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Tinkov
authors.affiliation: Department of Education and Obesity Treatment and Metabolic Disorders, University of Medical Sciences, Poznan, Poland.
authors.forename: P
authors.initials: P
authors.lastname: Bogdański
mesh_terms: D000328:Adult; D002118:Calcium / Q000097:blood*; D019587:Dietary Supplements; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications / Q000178:diet therapy; D007501:Iron / Q000097:blood*; D008274:Magnesium / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications / Q000178:diet therapy; D053545:Spirulina; D015032:Zinc / Q000097:blood*
chemical_list: D007501:Iron; D008274:Magnesium; D015032:Zinc; D002118:Calcium
keywords: Minerals; Obesity; Randomized trial; Spirulina; Treated hypertension