title: Multimodality treatment of intrahepatic cholangiocarcinoma: A review.
abstract: Intrahepatic cholangiocarcinoma (iCCA) is the second most common primary hepatic cancer in the United States. Currently, curative treatment involves aggressive surgery. Chemotherapy and radiation treatments have been used for unresectable tumors with some success. Optimizing the use of current and developing novel multimodality treatment for iCCA is essential to improving outcomes.
authors.affiliation: Hepatobiliary and Pancreas Surgery, ProMedica Health System, Toledo, Ohio.|ProMedica Cancer Institute, ProMedica Health System, Toledo, Ohio.|Department of Surgery, University of Toledo Medical College, Toledo, Ohio.
authors.forename: Kerri A
authors.initials: KA
authors.lastname: Simo
authors.affiliation: Department of Surgery, University of Toledo Medical College, Toledo, Ohio.
authors.forename: Laura E
authors.initials: LE
authors.lastname: Halpin
authors.affiliation: Hepatobiliary and Pancreas Surgery, ProMedica Health System, Toledo, Ohio.|ProMedica Cancer Institute, ProMedica Health System, Toledo, Ohio.
authors.forename: Nicole M
authors.initials: NM
authors.lastname: McBrier
authors.affiliation: Ohio Health Riverside Methodist Hosptial, Columbus, Ohio.
authors.forename: Jacob A
authors.initials: JA
authors.lastname: Hessey
authors.affiliation: Hepatobiliary and Pancreas Surgery, Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: Erin
authors.initials: E
authors.lastname: Baker
authors.affiliation: Hepatobiliary and Pancreas Surgery, Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: Samuel
authors.initials: S
authors.lastname: Ross
authors.affiliation: Hepatobiliary and Pancreas Surgery, Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: Ryan Z
authors.initials: RZ
authors.lastname: Swan
authors.affiliation: Hepatobiliary and Pancreas Surgery, Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: David A
authors.initials: DA
authors.lastname: Iannitti
authors.affiliation: Hepatobiliary and Pancreas Surgery, Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: John B
authors.initials: JB
authors.lastname: Martinie
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001650:Bile Duct Neoplasms / Q000453:epidemiology / Q000628:therapy*; D017115:Catheter Ablation; D018281:Cholangiocarcinoma / Q000453:epidemiology / Q000628:therapy*; D003131:Combined Modality Therapy / Q000379:methods*; D004621:Embolization, Therapeutic / Q000379:methods; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D011379:Prognosis; D061766:Proton Therapy; D016634:Radiosurgery; D014481:United States / Q000453:epidemiology; D015021:Yttrium Radioisotopes / Q000627:therapeutic use
chemical_list: D015021:Yttrium Radioisotopes
keywords: intrahepatic cholangiocarcinoma; multimodality