title: Papillary thyroid cancer located in malignant struma ovarii with omentum metastasis: a case report and review of the literature.
abstract: BACKGROUND
  The present of malignant transformation in struma ovarii is exceedingly rare. Malignant struma ovarii is usually asymptomatic and infrequently diagnosed preoperatively. Because of its rarity, there is no consensus about diagnosis and management in the literature.
  
  
  METHODS
  A 40-year-old female presented for her obstetric examination with an incidental finding of a pelvic mass. Patient was asymptomatic at presentation. A follow-up ultrasound confirmed the presence of a 3-cm mass in the left adnexa. Patient underwent a cytoreductive surgery (hysterectomy, bilateral salpingectomy and oophorectomy, omentectomy, appendectomy, and pelvic lymphadenectomy). Histopathology revealed a malignant struma ovarii with a focus of papillary thyroid carcinoma and the omentum metastasis. The patient with stage FIGO IIIc received 6 cycles of paclitaxel/carboplatin regimen after surgery. The patient subsequently had a thyroid scan that was normal with normal thyroid function. At a follow-up of 12 months, she is alive, in good clinical condition, and disease-free.
  
  
  CONCLUSIONS
  Because of the rarity of these tumors and their lack of firm prognostic factors, treatment decisions should be made individually, based on pathologic and clinical parameters.
authors.affiliation: Department of Gynecological Oncology, Sichuan Cancer Hospital, No. 55, Section 4, South People's Road, Chengdu, 610041, Sichuan, China. doczhuy@163.com.|Department of Ultrasound, Sichuan Cancer Hospital, Chengdu, Sichuan, China. doczhuy@163.com.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Department of Gynaecology and Obstetrics, Chengdu First People's Hospital, Chengdu, Sichuan, China. docwangc@163.com.
authors.forename: Chang
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Gynecological Oncology, Sichuan Cancer Hospital, No. 55, Section 4, South People's Road, Chengdu, 610041, Sichuan, China. zhanggn@hotmail.com.
authors.forename: Guo-Nan
authors.initials: GN
authors.lastname: Zhang
authors.affiliation: Department of Gynecological Oncology, Sichuan Cancer Hospital, No. 55, Section 4, South People's Road, Chengdu, 610041, Sichuan, China. lovejulie_2009@sina.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Department of Gynecological Oncology, Sichuan Cancer Hospital, No. 55, Section 4, South People's Road, Chengdu, 610041, Sichuan, China. julie.l.k@hotmail.com.
authors.forename: Shi-Qiang
authors.initials: SQ
authors.lastname: Xu
authors.affiliation: Department of Pathology, Sichuan Cancer Hospital, Chengdu, Sichuan, China. daxingxing-1@163.com.
authors.forename: Shi-Jun
authors.initials: SJ
authors.lastname: Jia
authors.affiliation: Department of Ultrasound, Sichuan Cancer Hospital, Chengdu, Sichuan, China. 410960600@qq.com.
authors.forename: Rong
authors.initials: R
authors.lastname: He
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000175:diagnosis / Q000556:secondary*; D002291:Carcinoma, Papillary; D005260:Female; D006801:Humans; D009852:Omentum; D010051:Ovarian Neoplasms / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000556:secondary*; D013330:Struma Ovarii / Q000175:diagnosis / Q000556:secondary*; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000556:secondary*