title: Small Immunoglobulin Domain Proteins at Synapses and the Maintenance of Neuronal Features.
abstract: The integrity of neural circuits must be maintained throughout the lifetime of an organism. In this issue of Neuron, Cherra and Jin (2016) characterize a small, two-Ig domain protein, ZIG-10, and its role in maintaining synaptic density in a specific set of C. elegans neurons.
authors.affiliation: Department of Biology, Howard Hughes Medical Institute, Columbia University, New York, NY 10032, USA. Electronic address: kh2512@cumc.columbia.edu.
authors.forename: Kelly
authors.initials: K
authors.lastname: Howell
authors.affiliation: Department of Biology, Howard Hughes Medical Institute, Columbia University, New York, NY 10032, USA. Electronic address: or38@columbia.edu.
authors.forename: Oliver
authors.initials: O
authors.lastname: Hobert
mesh_terms: D000818:Animals; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D004817:Epidermis / Q000378:metabolism*; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism*
chemical_list: D029742:Caenorhabditis elegans Proteins; D007136:Immunoglobulins