title: Knowledge-based 3D reconstruction of the right ventricle: comparison with cardiac magnetic resonance in adults with congenital heart disease.
abstract: OBJECTIVE
  Assessment of right ventricular (RV) function is a challenge, especially in patients with congenital heart disease (CHD). The aim of the present study is to assess whether knowledge-based RV reconstruction, used in the everyday practice of an echo-lab for adult CHD in a tertiary referral center, is accurate when compared to cardiac magnetic resonance (CMR) examination.
  
  
  METHODS
  Adult patients who would undergo CMR for assessment of the RV were asked to undergo an echo of the heart for further knowledge-based reconstruction (KBR). Echocardiographic images were acquired in standard views using a predefined imaging protocol. RV volumes and ejection fraction (EF) calculated using knowledge-based technology were compared with the CMR data of the same patient.
  
  
  RESULTS
  Nineteen consecutive patients with congenital right heart disease were studied. Median age of the patients was 28 years (range 46 years). Reconstruction was possible in 16 out of 19 patients (85%). RV volumes assessed with this new method were smaller than with CMR. Indexed end diastolic volumes were 114±17 ml vs 121±19 ml, P<0.05 and EFs were 45±8% vs 47±9%, P<0.05 respectively. The correlation between the methods was good with an intraclass correlation of 0.84 for EDV and 0.89 for EF, P value <0.001 in both cases.
  
  
  CONCLUSIONS
  KBR enables reliable measurement of RVs in patients with CHDs and can be used in clinical practice for analysis of volumes and EFs.
authors.affiliation: Department of Cardiology and Department of Medicine and Health Sciences, Linköping University, Linköping, Sweden; Department of Cardiology, AHMazON Center for Adult Congenital Heart Disease, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Trzebiatowska-Krzynska
authors.affiliation: Department of Cardiology, AHMazON Center for Adult Congenital Heart Disease, University Medical Center Utrecht , Utrecht , The Netherlands.
authors.forename: Mieke
authors.initials: M
authors.lastname: Driessen
authors.affiliation: Department of Cardiology, AHMazON Center for Adult Congenital Heart Disease, University Medical Center Utrecht , Utrecht , The Netherlands.
authors.forename: Gertjan Tj
authors.initials: GT
authors.lastname: Sieswerda
authors.affiliation: Department of Cardiology and Department of Medicine and Health Sciences, Linköping University , Linköping , Sweden.
authors.forename: Lars
authors.initials: L
authors.lastname: Wallby
authors.affiliation: Department of Cardiology and Department of Medicine and Health Sciences, Linköping University , Linköping , Sweden.
authors.forename: Eva
authors.initials: E
authors.lastname: Swahn
authors.affiliation: Department of Cardiology, AHMazON Center for Adult Congenital Heart Disease, University Medical Center Utrecht , Utrecht , The Netherlands.
authors.forename: Folkert
authors.initials: F
authors.lastname: Meijboom
keywords: congenital heart disease; knowledge-based reconstruction; right ventricle volume; ventripoint system