title: Lithium prophylaxis during pregnancy and the postpartum period in women with lithium-responsive bipolar I disorder.
abstract: The aim of this study was to evaluate the efficacy of lithium prophylaxis during the peripartum period in women with lithium-responsive bipolar I disorder. Seventeen lithium-treated patients were selected and underwent preconception counseling that included both a psychiatric and an obstetric evaluation. Treatment was continued with flexible-doses of lithium combined with supportive psychotherapy throughout the pregnancy and the postpartum period. The results support the prophylaxis efficacy of lithium in lithium-responder bipolar women who have a high risk of severe peripartum recurrences.
authors.affiliation: Department of Neuroscience, Psychiatric Unit, S Luigi Gonzaga Hospital, University of Turin, Turin, Italy.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Rosso
authors.affiliation: Department of Neuroscience, Anxiety and Mood Disorders Unit, University of Turin, Turin, Italy.
authors.forename: Umberto
authors.initials: U
authors.lastname: Albert
authors.affiliation: Department of Neuroscience, Psychiatric Unit, S Luigi Gonzaga Hospital, University of Turin, Turin, Italy.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Di Salvo
authors.affiliation: Department of Obstetrics and Gynecology, University of Turin, Turin, Italy.
authors.forename: Manuela
authors.initials: M
authors.lastname: Scatà
authors.affiliation: Department of Obstetrics and Gynecology, University of Turin, Turin, Italy.
authors.forename: Tullia
authors.initials: T
authors.lastname: Todros
authors.affiliation: Department of Neuroscience, Psychiatric Unit, S Luigi Gonzaga Hospital, University of Turin, Turin, Italy. giuseppe.maina@unito.it.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Maina
mesh_terms: D000328:Adult; D018692:Antimanic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control*; D019052:Depression, Postpartum / Q000517:prevention & control*; D005260:Female; D006801:Humans; D016651:Lithium Carbonate / Q000008:administration & dosage* / Q000627:therapeutic use; D049590:Postpartum Period / Q000523:psychology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000503:physiopathology*; D011446:Prospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D018692:Antimanic Agents; D016651:Lithium Carbonate
keywords: Bipolar disorder; Lithium; Postpartum; Pregnancy; Psychotherapy