title: Risk factors for infection after endoscopic ultrasonography-guided drainage of specific types of pancreatic and peripancreatic fluid collections (with video).
abstract: Endoscopic ultrasonography (EUS)-guided drainage is widely used for the treatment of specific types of peripancreatic fluid collections (PFCs). Infectious complications have been reported. It is recommended that the infection rate should be assessed by measuring risk factors. The objectives of this study were to measure whether the risk of infection after EUS-guided drainage was associated with patient- and procedure-related factors.
  
  
  
  Eighty-three patients were eligible for inclusion from September 2008 to November 2012. EUS-guided drainage was performed in all patients. Infectious complications were observed, and data on patient- and procedure-related factors were collected. Patient-related factors mainly included age, sex, etiology of PFC, and cyst location and diameter. Procedure-related factors mainly included approach of EUS-guided drainage and stent diameter. Separate multivariate logistic regression models for all EUS-guided drainage were carried out.
  
  
  
  Complete EUS-guided drainage was achieved in all patients. A definitive diagnosis of infection after EUS-guided drainage was made in seven patients. All seven patients had a history of acute pancreatitis, and the cyst diameters were all >15 cm. Three patients had diabetes mellitus.
  
  
  
  The cyst diameter was an independent risk factor for infection. Larger cysts with a diameter >15 cm should perhaps be drained initially with multiple pigtail or a larger diameter self-expandable metal stents to try to avoid infection.
authors.affiliation: Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
authors.forename: Jintao
authors.initials: J
authors.lastname: Guo
authors.affiliation: Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
authors.forename: Linlin
authors.initials: L
authors.lastname: Feng
authors.affiliation: Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning Province, China. sunsiyucmu@aliyun.com.
authors.forename: Siyu
authors.initials: S
authors.lastname: Sun
authors.affiliation: Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
authors.forename: Nan
authors.initials: N
authors.lastname: Ge
authors.affiliation: Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Liu
authors.affiliation: Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Wang
authors.affiliation: Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
authors.forename: Guoxin
authors.initials: G
authors.lastname: Wang
authors.affiliation: Endoscopy Center, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, 110004, Liaoning Province, China.
authors.forename: Beibei
authors.initials: B
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D020420:Cyst Fluid / Q000000981:diagnostic imaging*; D004322:Drainage / Q000009:adverse effects* / Q000379:methods; D019160:Endosonography / Q000009:adverse effects*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000000981:diagnostic imaging; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging*; D012307:Risk Factors; D015607:Stents
keywords: Complications; EUS-guided drainage; Infection; Peripancreatic fluid collections