title: Magnetic Resonance-Guided High-Intensity Focused Ultrasound Ablation of Osteoid Osteoma: A Case Series Report.
abstract: Osteoid osteoma is painful benign tumor. The aim of this study was to report our initial experience using magnetic resonance-guided focused ultrasound to treat osteoid osteomas. This retrospective single-center study included four patients treated with magnetic resonance-guided focused ultrasound. They presented with severe pain with reduced quality of life and a poor response to clinical treatment. The pre- and post-treatment evaluation comprised computed tomography and magnetic resonance imaging and focused on quality of life and the impact of pain on daily activities. After treatment, three patients had complete pain resolution with no recurrence. One patient had a recurrence of symptoms after 2 wk and underwent a new successful treatment with increased energy levels. On average, 13 sonications were administered (8-18 sonications/treatment) with an average energy of 2,003 J (range: 1,063-3,522 J). Magnetic resonance-guided focused ultrasound appears to be a feasible, tolerable and effective treatment in selected patients with osteoid osteomas.
authors.affiliation: Radiology and Image Guided Intervention Service, Instituto do Câncer do Estado de São Paulo, University of São Paulo, São Paulo, Brazil.
authors.forename: Marcello S
authors.initials: MS
authors.lastname: Rovella
authors.affiliation: Radiology and Image Guided Intervention Service, Instituto do Câncer do Estado de São Paulo, University of São Paulo, São Paulo, Brazil.
authors.forename: Guilherme L P
authors.initials: GL
authors.lastname: Martins
authors.affiliation: Radiology Department, Hospital Sírio Libanês, São Paulo, Brazil.
authors.forename: Conrado F A
authors.initials: CF
authors.lastname: Cavalcanti
authors.affiliation: Neurosurgery Department, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
authors.forename: Edson
authors.initials: E
authors.lastname: Bor-Seng-Shu
authors.affiliation: Orthopedics Department, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
authors.forename: Olavo P
authors.initials: OP
authors.lastname: Camargo
authors.affiliation: Radiology Department, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
authors.forename: Giovanni G
authors.initials: GG
authors.lastname: Cerri
authors.affiliation: Radiology and Image Guided Intervention Service, Instituto do Câncer do Estado de São Paulo, University of São Paulo, São Paulo, Brazil. Electronic address: marcos.menezes@hc.fm.usp.br.
authors.forename: Marcos R
authors.initials: MR
authors.lastname: Menezes
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D057086:High-Intensity Focused Ultrasound Ablation / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010017:Osteoma, Osteoid / Q000000981:diagnostic imaging / Q000601:surgery*; D025321:Surgery, Computer-Assisted / Q000379:methods*; D016896:Treatment Outcome
keywords: Ablation; Magnetic resonance-guided focused ultrasound; Osteoid osteoma