title: Aphasia and unilateral spatial neglect due to acute thalamic hemorrhage: clinical correlations and outcomes.
abstract: Thalamic hemorrhages are associated with a variety of cognitive dysfunctions, and it is well known that such cognitive changes constitute a limiting factor of recovery of the activities of daily living (ADL). The relationship between cognitive dysfunction and hematomas is unclear. In this study, we investigated the relationship between aphasia/neglect and hematoma volume, hematoma type, and the ADL. One hundred fifteen patients with thalamic hemorrhage (70 men and 45 women) were studied. Their mean age was 68.9 ± 10.3 years, and patients with both left and right lesions were included. We calculated hematoma volume and examined the presence or absence of aphasia/neglect and the relationships between these dysfunctions and hematoma volume, hematoma type, and the ADL. Fifty-nine patients were found to have aphasia and 35 were found to have neglect. Although there was no relationship between hematoma type and cognitive dysfunction, hematoma volume showed a correlation with the severity of cognitive dysfunction. The ADL score and ratio of patient discharge for patients with aphasia/neglect were lower than those for patients without aphasia/neglect. We observed a correlation between the hematoma volume in thalamic hemorrhage and cognitive dysfunction. Aphasia/neglect is found frequently in patients with acute thalamic hemorrhage and may influence the ADL.
authors.affiliation: Department of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.
authors.forename: Aiko
authors.initials: A
authors.lastname: Osawa
authors.affiliation: Department of Rehabilitation Medicine II, School of Medicine, Fujita Health University, Nanakuri Memorial Hospital, 424-1 Oodori-cho, Tsu, 514-1295, Japan. maeshima@saitama-med.ac.jp.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Maeshima
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001037:Aphasia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000534:rehabilitation; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000000981:diagnostic imaging / Q000534:rehabilitation; D005260:Female; D007839:Functional Laterality; D006406:Hematoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000534:rehabilitation; D006801:Humans; D008297:Male; D008875:Middle Aged; D010468:Perceptual Disorders / Q000000981:diagnostic imaging / Q000209:etiology* / Q000534:rehabilitation; D012720:Severity of Illness Index; D013028:Space Perception; D013786:Thalamic Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000534:rehabilitation; D013788:Thalamus / Q000000981:diagnostic imaging
keywords: Activities of daily living; Aphasia; Intracerebral hemorrhage; Neglect; Thalamus