title: Antioxidant Effect of Lippia alba (Miller) N. E. Brown.
abstract: Lippia alba is a shrub found in all regions of Brazil and other countries in South and Central America. L. alba exhibits variability among its different accessions, showing differences in morphology and in the composition of its essential oil. This study evaluated the phenolic profiles and the antioxidant activities of seven different accessions of L. alba. The seven accessions of L. alba studied exhibited an important phenolic content, and all accessions demonstrated antioxidant activity with different efficacies. The main flavonoids in all accessions were apigenin, luteolin, naringin and rutin. The Santa Vitória do Palmar accession exhibited higher naringin and total phenolic content. This extract was able to reduce hydrogen peroxide-induced oxidative damage in tissue homogenates of cerebellum, cerebral cortex, hippocampus and liver of Wistar rats.
authors.affiliation: Institute of Biotechnology, University of Caxias do Sul, Caxias do Sul, RS 95070560, Brazil. cechies@yahoo.com.br.
authors.forename: Claire E
authors.initials: CE
authors.lastname: Chies
authors.affiliation: Institute of Biotechnology, University of Caxias do Sul, Caxias do Sul, RS 95070560, Brazil. csbranc1@ucs.br.
authors.forename: Cátia S
authors.initials: CS
authors.lastname: Branco
authors.affiliation: Institute of Biotechnology, University of Caxias do Sul, Caxias do Sul, RS 95070560, Brazil. gustavo.scola@gmail.com.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Scola
authors.affiliation: Institute of Biotechnology, University of Caxias do Sul, Caxias do Sul, RS 95070560, Brazil. fagosti1@ucs.br.
authors.forename: Fabiana
authors.initials: F
authors.lastname: Agostini
authors.affiliation: Institute of Biotechnology, University of Caxias do Sul, Caxias do Sul, RS 95070560, Brazil. aegower@ucs.br.
authors.forename: Adriana E
authors.initials: AE
authors.lastname: Gower
authors.affiliation: Institute of Biotechnology, University of Caxias do Sul, Caxias do Sul, RS 95070560, Brazil. msalvado@ucs.br.
authors.forename: Mirian
authors.initials: M
authors.lastname: Salvador
keywords: Lippia alba; antioxidant; flavonoids; radical scavenger