title: Bioaccumulation and tissue distribution of Pb and Cd and growth effects in the green garden snail, Cantareus apertus (Born, 1778), after dietary exposure to the metals alone and in combination.
abstract: The present study was aimed at determining bioaccumulation and cell and tissue distribution of Pb and Cd in the green garden snail, Cantareus apertus (Born, 1778), exposed to different nominal dietary concentrations of Pb (25, 100 and 2500 mg Pb/kg), Cd (5, 10 and 100 mg Cd/kg) and their combination (25mg Pb+10 mg Cd/kg and 2500 mg Pb+100 mg Cd/kg) for 1 and 8 wk. Pb and Cd were bioaccumulated in the digestive gland in a dose-dependent manner and the degree of effects on growth was related to the level of exposure, though metal-metal interactions were observed after treatment with mixtures of Pb and Cd. The present results are absolutely comparable to those obtained in other terrestrial pulmonates in other regions and therefore they absolutely support that C. apertus is suitable as biomonitor for the assessment of the Pb and Cd levels and their biological effects in soil ecosystems in Northern Africa.
authors.affiliation: University of Carthage, Faculty of Sciences of Bizerta, Laboratory of Environment Bio-monitoring, 7021, Zarzouna, Bizerta, Tunisia.
authors.forename: Anwar
authors.initials: A
authors.lastname: Mleiki
authors.affiliation: CBET Research Group, BERRILUR Research Consortium, Zoology & Cell Biology Dept. (Science and Technology Faculty), University of the Basque Country (UPV/EHU), Sarriena w/n, Leioa-Bizkaia E-48940, Basque Country, Spain.
authors.forename: Amaia
authors.initials: A
authors.lastname: Irizar
authors.affiliation: CBET Research Group, Research Centre for Experimental Marine Biology and Biotechnology (PiE-UPV/EHU), University of the Basque Country (UPV/EHU), Areatza w/n, Plentzia-Bizkaia E-48620, Basque Country, Spain; CBET Research Group, BERRILUR Research Consortium, Zoology & Cell Biology Dept. (Science and Technology Faculty), University of the Basque Country (UPV/EHU), Sarriena w/n, Leioa-Bizkaia E-48940, Basque Country, Spain.
authors.forename: Beñat
authors.initials: B
authors.lastname: Zaldibar
authors.affiliation: University of Carthage, Faculty of Sciences of Bizerta, Laboratory of Environment Bio-monitoring, 7021, Zarzouna, Bizerta, Tunisia.
authors.forename: Najoua Trigui
authors.initials: NT
authors.lastname: El Menif
authors.affiliation: CBET Research Group, Research Centre for Experimental Marine Biology and Biotechnology (PiE-UPV/EHU), University of the Basque Country (UPV/EHU), Areatza w/n, Plentzia-Bizkaia E-48620, Basque Country, Spain; CBET Research Group, BERRILUR Research Consortium, Zoology & Cell Biology Dept. (Science and Technology Faculty), University of the Basque Country (UPV/EHU), Sarriena w/n, Leioa-Bizkaia E-48940, Basque Country, Spain. Electronic address: ionan.marigomez@ehu.eus.
authors.forename: Ionan
authors.initials: I
authors.lastname: Marigómez
mesh_terms: D000818:Animals; D002104:Cadmium / Q000378:metabolism* / Q000633:toxicity; D004784:Environmental Monitoring; D006372:Helix, Snails / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D007854:Lead / Q000378:metabolism* / Q000633:toxicity; D012989:Soil Pollutants / Q000378:metabolism* / Q000633:toxicity; D014018:Tissue Distribution
chemical_list: D012989:Soil Pollutants; D002104:Cadmium; D007854:Lead
keywords: Autometallography; Cantareus apertus; Feeding activity; Growth; Metal tissue concentration