title: Normative Spectral Domain Optical Coherence Tomography Data in Healthy Turkish Children.
abstract: OBJECTIVE
  To determine the normative database of macular and retinal nerve fiber layer (RNFL) thickness parameters in healthy Turkish children by OCT.
  
  
  METHODS
  318 eyes of 318 children (138 boys, 183 girls) aged between 3 and 17 years were evaluated. The children were scanned by Cirrus HD-OCT (Carl Zeiss Meditec) to measure the macula, RNFL, and optic nerve head parameters.
  
  
  RESULTS
  Axial length (AL) (p < 0.001, R2= 0.08), spherical equivalent (SE) (p < 0.001, R2= 0.12), and rim area (p < 0.001, R2= 0.15) were the strongest predictors of RNFL thickness. All of the macular measurements were significantly related to age (p < 0.001, R2> 5%). Average macular thickness (p < 0.01) and outer macula (p = 0.002) showed significant relationship with the AL and SE.
  
  
  CONCLUSIONS
  This study ensures an age-adjusted pediatric normative database using OCT to diagnose and monitor macular diseases, optic nerve diseases, and glaucoma in children.
authors.affiliation: a Gölbaşı Hasvak State Hospital, Eye Clinic , Ankara , Turkey.
authors.forename: Fatma Betül
authors.initials: FB
authors.lastname: Gürağaç
authors.affiliation: b Turgut Özal University, Medical School, Department of Ophthalmology , Ankara , Turkey , and.
authors.forename: Yüksel
authors.initials: Y
authors.lastname: Totan
authors.affiliation: c Erciş State Hospital, Eye Clinic , Van , Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Güler
authors.affiliation: b Turgut Özal University, Medical School, Department of Ophthalmology , Ankara , Turkey , and.
authors.forename: Aylin
authors.initials: A
authors.lastname: Tenlik
authors.affiliation: a Gölbaşı Hasvak State Hospital, Eye Clinic , Ankara , Turkey.
authors.forename: İhsan Gökhan
authors.initials: İG
authors.lastname: Ertuğrul
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D015994:Incidence; D008266:Macula Lutea / Q000000981:diagnostic imaging*; D008297:Male; D009412:Nerve Fibers / Q000473:pathology; D012164:Retinal Diseases / Q000175:diagnosis / Q000453:epidemiology; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D014421:Turkey
keywords: Central macular thickness; Cirrus HD-OCT; normative database; pediatric OCT; retinal nerve fiber layer