title: Effect of simple and radical hysterectomy on quality of life - analysis of all aspects of pelvic floor dysfunction.
abstract: OBJECTIVE
  The impact of simple and radical hysterectomy on all aspects of pelvic floor dysfunctions was evaluated in current study.
  
  
  METHODS
  This retrospective cohort study included 142 patients; 58 women (40.8%) who have undergone simple, 41 (28.8%) radical hysterectomy, and 43 (30.2%) women without any surgical intervention to serve as the control group. The validated versions of the Urogenital Distress Inventory (UDI-6), Incontinence Impact Questionnaire (IIQ-7), Pelvic Floor and Incontinence Sexual Impact Questionnaire (PISQ-12), Wexner Incontinence Scale score and pelvic organ prolapse quantification (POP-Q) system were used in detailed evaluation of pelvic floor dysfunction. One-way ANOVA and Pearson's chi square tests were performed in statistical analysis.
  
  
  RESULTS
  It was found that there were significant differences in irritative and obstructive scores of UDI-6 between Type III hysterectomy group and Type I hysterectomy group. In addition, patients of Type I hysterectomy had significant higher irritative and obstructive scores than the control group. Type III hysterectomy had the most significant deteriorating effect on sexual life, based on scores of PISQ-12 compared to both Type I hysterectomy group and control group.
  
  
  CONCLUSIONS
  Hysterectomy results in detrimental effects on the quality of life (QoL) regarding all aspects of pelvic floor functions especially in women of radical hysterectomy. Urinary dysfunctional symptoms like urgency, obstruction and especially sexual problems are more bothersome and difficult to overcome. The impact of hysterectomy on QoL should be investigated as a whole and may be more profound than previously thought.
authors.affiliation: Zeynep Kamil Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey. Electronic address: md_sel@hotmail.com.
authors.forename: Selcuk
authors.initials: S
authors.lastname: Selcuk
authors.affiliation: Zeynep Kamil Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Cetin
authors.initials: C
authors.lastname: Cam
authors.affiliation: The University of Texas, Department of Gynecology, Galveston, TX, USA.
authors.forename: Mehmet Resit
authors.initials: MR
authors.lastname: Asoglu
authors.affiliation: Zeynep Kamil Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kucukbas
authors.affiliation: Zeynep Kamil Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Arinkan
authors.affiliation: Zeynep Kamil Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Muzaffer Seyhan
authors.initials: MS
authors.lastname: Cikman
authors.affiliation: Zeynep Kamil Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Ates
authors.initials: A
authors.lastname: Karateke
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects* / Q000379:methods; D008875:Middle Aged; D017773:Pelvic Floor / Q000601:surgery*; D059952:Pelvic Floor Disorders / Q000209:etiology* / Q000523:psychology; D056887:Pelvic Organ Prolapse / Q000209:etiology* / Q000523:psychology; D011788:Quality of Life / Q000523:psychology*; D012189:Retrospective Studies; D012725:Sexual Behavior; D012735:Sexual Dysfunction, Physiological / Q000209:etiology* / Q000523:psychology; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000209:etiology* / Q000523:psychology
keywords: Anal incontinence; Pelvic organ prolapse; Quality of life; Radical hysterectomy; Sexual dysfunction; Urinary incontinence