title: Mitochondrial Dynamics and the ER: The Plant Perspective.
abstract: Whereas contact sites between mitochondria and the ER have been in the focus of animal and fungal research for several years, the importance of this organellar interface and the molecular effectors are largely unknown for plants. This work gives an introduction into known evolutionary differences of molecular effectors of mitochondrial dynamics and interactions between animals, fungi, and plants. Using the model plant Physcomitrella patens, we provide microscopic evidence for the existence of mitochondria-ER interactions in plants and their correlation with mitochondrial constriction and fission. We further investigate a previously identified protein of unknown function (MELL1), and show that it modulates the amount of mitochondrial association to the ER, as well as mitochondrial shape and number.
authors.affiliation: Plant Biotechnology, Faculty of Biology, University of Freiburg Freiburg, Germany.
authors.forename: Stefanie J
authors.initials: SJ
authors.lastname: Mueller
authors.affiliation: Plant Biotechnology, Faculty of Biology, University of FreiburgFreiburg, Germany; BIOSS Centre for Biological Signalling Studies, University of FreiburgFreiburg, Germany; FRIAS Freiburg Institute for Advanced Studies, University of FreiburgFreiburg, Germany; USIAS University of Strasbourg Institute for Advanced Study, University of StrasbourgStrasbourg, France.
authors.forename: Ralf
authors.initials: R
authors.lastname: Reski
keywords: Arabidopsis thaliana; Physcomitrella patens; fission; fusion; organelle dynamics