title: Subcutaneous Axillary and Scalp Metastases from Non-Gynecological Retroperitoneal Leiomyosarcoma: An Unusual Presentation After Surgical Resection.
abstract: Retroperitoneal leiomyosarcomas are rare sarcomas, with an incidence of less than 2 per million population. Cutaneous metastases from sarcoma account for only 1-2.6% of metastatic skin lesions. Cutaneous and subcutaneous metastasis from retroperitoneal leiomyosarcoma is a very rare entity. We present a case of 72-year-old male with scalp nodule and subcutaneous swelling in left posterior axillary fold. Fine needle aspiration cytology from both these sites revealed a sarcoma, which was positive for Smooth Muscle Actin and negative for S100 on cell block immuno-histochemistry (IHC). The past history revealed surgical resection of a retroperitoneal mass in 2010 which was diagnosed on histopathology and IHC as leiomyosarcoma. A final diagnosis of metastatic deposits from leiomyosarcoma was made. Retroperitoneal leiomyosarcoma presenting as scalp and subcutaneous metastasis is an unusual presentation. Adequate clinical history and a high index of clinical suspicion is required to detect cutaneous and subcutaneous metastatic deposits occurring five years after surgical resection.
authors.affiliation: Department of Pathology, Dayanand Medical College and Hospital , Ludhiana, India.
authors.forename: Simrandeep
authors.initials: S
authors.lastname: Kaur
authors.affiliation: Department of Pathology, Dayanand Medical College and Hospital , Ludhiana, India.
authors.forename: Ruchita
authors.initials: R
authors.lastname: Tyagi
authors.affiliation: Department of Pathology, Dayanand Medical College and Hospital , Ludhiana, India.
authors.forename: Pavneet
authors.initials: P
authors.lastname: Selhi
authors.affiliation: Department of Pathology, Dayanand Medical College and Hospital , Ludhiana, India.
authors.forename: Aminder
authors.initials: A
authors.lastname: Singh
authors.affiliation: Department of Pathology, Dayanand Medical College and Hospital , Ludhiana, India.
authors.forename: Harpreet
authors.initials: H
authors.lastname: Puri
authors.affiliation: Department of Pathology, Dayanand Medical College and Hospital , Ludhiana, India.
authors.forename: Neena
authors.initials: N
authors.lastname: Sood
keywords: Leiomyosarcoma; metastasis; retroperitoneal; scalp; subcutaneous