title: Challenge-proven immediate type multiple local anesthetic hypersensitivity in a child.
abstract: Adverse reactions to local anesthetics (LA) are commonly reported in patients undergoing dental procedures and other minor surgical procedures. Most of these reactions, however, originate from psychosomatic, vasovagal or toxic conditions and are not immune-mediated. True immune-mediated reactions are considered extremely rare and are estimated to account for less than 1% of all adverse reactions to LA. On the other hand, almost all of the immune-mediated LA reactions that have been reported are related to adult patients. Here, however, we will present a pediatric case proven to be hypersensitive to two different amide-derivative LA's.
authors.affiliation: Department of Pediatric Allergy and Asthma, Gazi University School of Medicine, Ankara, Turkey. E-mail: theilbilge@yahoo.com.au.
authors.forename: I
authors.initials: I
authors.lastname: Ertoy Karagol
authors.affiliation: Department of Pediatric Allergy and Asthma, Gazi University School of Medicine, Ankara, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Yilmaz
authors.affiliation: Department of Pediatric Allergy and Asthma, Gazi University School of Medicine, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Bakirtas
mesh_terms: D000779:Anesthetics, Local / Q000009:adverse effects*; D002648:Child; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000139:chemically induced* / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D012882:Skin Tests
chemical_list: D000779:Anesthetics, Local
keywords: challenge-proven; child; immediate hypersensitivity; local anesthetic; multiple