title: [Hepatocellular Carcinoma with Vp3 Tumor Thrombosis Treated with Multidisciplinary Treatment--Report of Two Cases].
abstract: Hepatic resection of hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) at the bifurcation of the portal has the potential to cure the disease. Herein, we report 2 cases of HCC with Vp3 treated with a multidisciplinary approach that might include preoperative transcatheter arterial chemoembolization (TACE) or postoperative hepatic arterial infusion chemotherapy (HAIC). Case 1: A 73-year-old man was diagnosed with HCC with Vp3 located in segment 1 during follow up that was treated by performing a left hepatectomy with removal of the tumor thrombus. After surgery, the patient underwent HAIC, and he was alive without disease recurrence 2 years and 2 months after surgery. Case 2: A 77-year-old man with cirrhotic nonalcoholic steatohepatitis underwent liver resection followed by TACE. However, recurrent HCC with Vp3 was detected in segments 2 and 5, so we performed a repeat liver resection. The patient was alive without disease recurrence 1 year and 8 months after surgery without having received postoperative adjuvant chemotherapy. In select patients diagnosed with HCC with PVTT (Vp3/4), long-term survival can be obtained with multidisciplinary treatment such as surgery and preoperative TACE or postoperative HAIC.
authors.affiliation: Dept. of Surgery, Saitama Red Cross Hospital.
authors.forename: Yangi
authors.initials: Y
authors.lastname: Mun
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yoshidome
authors.forename: Kazuyasu
authors.initials: K
authors.lastname: Shinmura
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nishida
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Sato
authors.forename: Junichi
authors.initials: J
authors.lastname: Nakamura
authors.forename: Keiji
authors.initials: K
authors.lastname: Kato
authors.forename: Akira
authors.initials: A
authors.lastname: Oki
authors.forename: Shigeru
authors.initials: S
authors.lastname: Sasaki
authors.forename: Masaru
authors.initials: M
authors.lastname: Miyazaki
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D003131:Combined Modality Therapy; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000628:therapy*; D008297:Male; D012008:Recurrence; D013927:Thrombosis / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome