title: Event-related Potential Patterns Reflect Reversed Hemispheric Activity during Visual Attention Processing in Children with Dyslexia: A Preliminary Study.
abstract: OBJECTIVE
  Individuals with dyslexia experience reading difficulties, whereas their other cognitive abilities seem normal. The purpose of this study was to investigate the event-related potential (ERP) patterns of children with dyslexia during a target-detection task.
  
  
  METHODS
  Seventeen children with dyslexia and 18 children without this disorder participated in this study. We evaluated their writing and reading ability, symptoms of attention-deficit/hyperactivity disorder, and intelligence quotient. ERPs were recorded while participants performed a target-detection task, and the peak amplitude and latency of P100 and P300 were analyzed. The lateral asymmetry index (LAI) was calculated for each ERP component.
  
  
  RESULTS
  The dyslexic group exhibited longer reaction times and larger P100 amplitudes than the non-dyslexic group in the right hemisphere. The P100 latency was also significantly delayed in the right hemisphere of those in the dyslexic group compared with those in the non-dyslexic group. The P300 amplitude was larger in the right hemisphere compared with left hemisphere in the dyslexic group, whereas no interhemispheric differences were observed with respect to the P300 latency. The LAI for P100 showed a significant right hemispheric dominance, whereas the LAI for P100 was significantly correlated with the accuracy of target detection in children with dyslexia.
  
  
  CONCLUSIONS
  Our results suggest that right hemispheric dominance acts as an ancillary system that compensates for poor reading in children with dyslexia.
authors.affiliation: Department of Optometry, Eulji University, Daejeon, Korea.|Clinical Emotion and Cognition Research Laboratory, Goyang, Korea.
authors.forename: Joong-Gu
authors.initials: JG
authors.lastname: Kang
authors.affiliation: Clinical Emotion and Cognition Research Laboratory, Goyang, Korea.|Department of Psychiatry, Inje University Ilsan Paik Hospital, Goyang, Korea.
authors.forename: Seung-Hwan
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Psychiatry, Inje University Ilsan Paik Hospital, Goyang, Korea.
authors.forename: Eun-Jin
authors.initials: EJ
authors.lastname: Park
authors.affiliation: Department of Optometry, Eulji University, Daejeon, Korea.
authors.forename: Hyun-Sung
authors.initials: HS
authors.lastname: Leem
keywords: Child; Dyslexia; Event-related potential; Right hemisphere; Visual attention