title: Isodicentric Philadelphia chromosome: an uncommon chromosomal abnormality in the chronic phase of chronic myeloid leukemia (CML).
abstract: An isodicentric Philadelphia chromosome is an uncommon finding previously described as a secondary chromosomal abnormality in accelerated- or blast-phase of chronic myeloid leukemia (CML) with resistance to imatinib mesylate or dasatinib. Here, we present a case with idic(Ph) chromosome identified at initial diagnosis in a patient with chronic-phase CML.
authors.affiliation: Department of Pathology University of New Mexico Albuquerque New Mexico.
authors.forename: Eric
authors.identifier: 0000-0002-7089-2169
authors.initials: E
authors.lastname: Loo
authors.affiliation: Department of Medicine University of New Mexico Albuquerque New Mexico.
authors.forename: Pranshu
authors.initials: P
authors.lastname: Bansal
authors.affiliation: Department of Pathology University of New Mexico Albuquerque New Mexico.
authors.forename: Durga
authors.initials: D
authors.lastname: Cherukuri
authors.affiliation: Department of Medicine University of New Mexico Albuquerque New Mexico.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Arana Yi
keywords: CML; cytogenetics; isodicentric; philadelphia chromosome