title: [A Case of Bullous Pemphigoid Relieved after Sigmoid Colon Cancer Resection].
abstract: A 76-year-old man presented with many bullous lesions and erythema over his whole body in August 2014. Blood examination showed an elevation of the anti-BP180 antibody (658 U/mL) and a biopsied specimen of the skin lesions showed subepidermal bulla. A diagnosis of bullous pemphigoid was made based on the clinical and histological findings. Although 20 mg/day of prednisolone was administered, there was a poor response and consequently the dose of steroid was increased to 70 mg/day after 2 weeks. Bullous pemphigoid related to a malignant tumor was suspected. Colonic endoscopic examination revealed a sigmoid colon cancer and he underwent a sigmoidectomy with lymphodenectomy. The histopathological findings revealed a moderately-differentiated adenocarcinoma, pT1b, pN1, pStage Ⅲa, and he received adjuvant chemotherapy(UFT/ LV). The dermatological findings were rapidly relieved after tumor resection and anti-BP180 antibody was normalized. He has had no signs or symptoms of recurrence, both of the cancer and the bullous pemphigoid, for 9 months after the operation.
authors.affiliation: Dept. of Gastroenterological Surgery, Aichi Medical University Hospital.
authors.forename: Kengo
authors.initials: K
authors.lastname: Kimura
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Mishima
authors.forename: Jun
authors.initials: J
authors.lastname: Muto
authors.forename: Kenichi
authors.initials: K
authors.lastname: Komaya
authors.forename: Takuya
authors.initials: T
authors.lastname: Saito
authors.forename: Keiichi
authors.initials: K
authors.lastname: Ando
authors.forename: Seiji
authors.initials: S
authors.lastname: Ishiguro
authors.forename: Norifumi
authors.initials: N
authors.lastname: Ohashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Arikawa
authors.forename: Shunichirou
authors.initials: S
authors.lastname: Komatsu
authors.forename: Masahiko
authors.initials: M
authors.lastname: Miyachi
authors.forename: Daisuke
authors.initials: D
authors.lastname: Watanabe
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Sano
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010391:Pemphigoid, Bullous / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D012811:Sigmoid Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone