title: [Treatment for Elderly Breast Cancer Patients Older than 80 Years].
abstract: Breast cancer is the leading form of cancer in women in Japan. Cases of elderly women with breast cancer have been increasing rapidly in Japan due to the increasing age of the population. We examined the clinicopathological features and prognosis of breast cancer patients over 80 years old to define an optimal treatment regimen. From January 2004 to October 2014, 43 primary breast cancer patients underwent surgery at the Chiba Rosai Hospital. The median age was 84 years. On pathological diagnosis, the median tumor diameter was 2.4 cm. The tumors were positive for estrogen and progesterone receptors in 30 and 26 patients, respectively. The median overall survival time was 78 months. Only lymph node metastasis was an important predictor of overall survival. It is important to appropriately treat elderly patients. However, there have been no clinical practice guidelines for the management of breast cancer in elderly individuals because of a lack of clinical trials including elderly patients. Elderly patients have other complications such as cardiovascular disease, diabetes, dementia, and pulmonary emphysema. Therefore, we need to make a clinical decision for each individual patient considering comorbidities, functional status, and clinicopathological characteristics of the tumor.
authors.affiliation: Dept. of Surgery, Chiba Rosai Hospital.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Fujimori
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kasagawa
authors.forename: Natsumi
authors.initials: N
authors.lastname: Ishii
authors.forename: Ikuo
authors.initials: I
authors.lastname: Udagawa
mesh_terms: D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D012189:Retrospective Studies
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone