title: High frequency repetitive transcranial magnetic stimulation (rTMS) reduces EEG-hypofrontality in patients with schizophrenia.
abstract: The reduced metabolic activity in the prefrontal brain lobes, so-called hypofrontality, is associated with increased electrophysiological delta-band activity. Schizophrenia inpatients (N=35) received sham-controlled 10Hz rTMS over the left dorsolateral prefrontal cortex in a randomised design. After treatment, the resting electroencephalography revealed a significant decrease in the delta-band activity, which originated in the right prefrontal cortex and correlated with improvements in facial affect recognition.
authors.affiliation: Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Bergische Landstr. 2, D-40629 Düsseldorf, Germany. Electronic address: Daniel.Kamp@lvr.de.
authors.forename: Daniel
authors.initials: D
authors.lastname: Kamp
authors.affiliation: Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Bergische Landstr. 2, D-40629 Düsseldorf, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Brinkmeyer
authors.affiliation: Department of Psychiatry, Psychotherapy and Preventive Medicine, Ruhr-University Bochum, Alexandrinenstr. 1-3, 44791 Bochum, Germany.
authors.forename: Marcus W
authors.initials: MW
authors.lastname: Agelink
authors.affiliation: Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Bergische Landstr. 2, D-40629 Düsseldorf, Germany.
authors.forename: Mareke
authors.initials: M
authors.lastname: Habakuck
authors.affiliation: Department of Psychiatry and Psychotherapy, Johannes Gutenberg-University Mainz, Untere Zahlbacher Str. 8, 55131 Mainz, Germany.
authors.forename: Arian
authors.initials: A
authors.lastname: Mobascher
authors.affiliation: Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Bergische Landstr. 2, D-40629 Düsseldorf, Germany.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Wölwer
authors.affiliation: Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine University, Bergische Landstr. 2, D-40629 Düsseldorf, Germany.
authors.forename: Joachim
authors.initials: J
authors.lastname: Cordes
mesh_terms: D000328:Adult; D001921:Brain / Q000503:physiopathology; D003700:Delta Rhythm; D004569:Electroencephalography; D000066499:Facial Recognition; D005260:Female; D006801:Humans; D008297:Male; D017397:Prefrontal Cortex / Q000503:physiopathology; D012559:Schizophrenia / Q000628:therapy*; D012565:Schizophrenic Psychology; D050781:Transcranial Magnetic Stimulation / Q000379:methods*
keywords: Delta-band; Facial affect recognition; sLORETA