title: Supramolecular architecture of betulin diacetate complexes with arabinogalactan from Larix sibirica.
abstract: Supramolecular ensembles of arabinogalactan (AG) and its complexes with betulin diacetate (BDA) were studied in water and dimethyl sulfoxide (DMSO) using ablation, induced by submillimeter radiation from the free electron laser. Solutions of 1wt% AG resulted in formation of aerosol particles with a maximum size of 60-70nm. In contrast, with DMSO as the solvent, the majority of particles were significantly smaller. Nevertheless, the addition of water shifted the particle size distribution to a larger size, suggesting the cross-linking of AG chains due to hydrogen bonding through water molecules. The ensembles of molecules were larger in solutions of the AG-BDA complex as compared to pure AG aqueous solution, and the distribution was narrow. The role of side chain interactions in the formation of AG-BDA complexes in aqueous solutions was confirmed by NMR.
authors.affiliation: Institute of Solid State Chemistry and Mechanochemistry SB RAS, Kutateladze str., 18, Novosibirsk 630128, Russia.
authors.forename: Mikhail A
authors.initials: MA
authors.lastname: Mikhailenko
authors.affiliation: Institute of Solid State Chemistry and Mechanochemistry SB RAS, Kutateladze str., 18, Novosibirsk 630128, Russia; Novosibirsk State University, Pirogova str., 2, Novosibirsk 630090, Russia. Electronic address: shah@solid.nsc.ru.
authors.forename: Tatyana P
authors.initials: TP
authors.lastname: Shakhtshneider
authors.affiliation: Novosibirsk State University, Pirogova str., 2, Novosibirsk 630090, Russia.
authors.forename: Ilia V
authors.initials: IV
authors.lastname: Eltsov
authors.affiliation: Institute of Chemical Kinetics and Combustion SB RAS, Institutskaya str., 3, Novosibirsk 630090, Russia.
authors.forename: Alexander S
authors.initials: AS
authors.lastname: Kozlov
authors.affiliation: Institute of Chemistry and Chemical Technology SB RAS, Academgorodok, 50/24, Krasnoyarsk 660036, Russia; Siberian Federal University, Svobodny pr., 79/10, Krasnoyarsk 660041, Russia.
authors.forename: Svetlana A
authors.initials: SA
authors.lastname: Kuznetsova
authors.affiliation: Institute of Chemistry and Chemical Technology SB RAS, Academgorodok, 50/24, Krasnoyarsk 660036, Russia; Siberian Federal University, Svobodny pr., 79/10, Krasnoyarsk 660041, Russia.
authors.forename: Аnton А
authors.initials: АА
authors.lastname: Karacharov
authors.affiliation: Institute of Solid State Chemistry and Mechanochemistry SB RAS, Kutateladze str., 18, Novosibirsk 630128, Russia; Novosibirsk State University, Pirogova str., 2, Novosibirsk 630090, Russia.
authors.forename: Vladimir V
authors.initials: VV
authors.lastname: Boldyrev
mesh_terms: D004121:Dimethyl Sulfoxide / Q000737:chemistry; D005685:Galactans / Q000737:chemistry*; D006860:Hydrogen Bonding; D028221:Larix / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D018625:Microscopy, Atomic Force; D010316:Particle Size; D014315:Triterpenes / Q000737:chemistry*; D014867:Water / Q000737:chemistry; D000094062:Betulinic Acid
chemical_list: D004121:Dimethyl Sulfoxide; D005685:Galactans; D014315:Triterpenes; D014867:Water; C002503:betulin; D000094062:Betulinic Acid; C005653:arabinogalactan
keywords: Arabinogalactan; Arabinogalactan–betulin diacetate complex; Betulin diacetate; NMR; Polymer associates; THz laser ablation