title: [A Case of Laparoscopic Gastrectomy for Gastric GIST after Neoadjuvant Chemotherapy with Imatinib Mesylate].
abstract: We report the case of a 68-year-old woman who underwent laparoscopic gastrectomy for a gastric gastrointestinal stromal tumor (GIST) after neoadjuvant chemotherapy with imatinib mesylate. After conducting gastroscopy because of weight loss and anemia, we identified a submucosal tumor in the cardia. A GIST of 8 cm in diameter invaded the pancreatic tail and excluded the splenic vein. We administered imatinib 400 mg/day as neoadjuvant chemotherapy. We performed laparoscopic partial gastrectomy 5 months after the initiation of chemotherapy. According to the histopathological diagnosis, the surgical margin was positive. As an additional excision, we performed laparoscopic proximal gastrectomy. Without postoperative complications, it passes smoothly as of 5 months after surgery.
authors.affiliation: Dept. of Surgery, Arao Municipal Hospital.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iwanaga
authors.forename: Shinichi
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Yukika
authors.initials: Y
authors.lastname: Tsukamoto
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Hamaguchi
authors.forename: Takashi
authors.initials: T
authors.lastname: Katsumori
authors.forename: Hisami
authors.initials: H
authors.lastname: Ohshima
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D005743:Gastrectomy; D046152:Gastrointestinal Stromal Tumors / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D000068877:Imatinib Mesylate / Q000627:therapeutic use*; D010535:Laparoscopy; D020360:Neoadjuvant Therapy; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents; D000068877:Imatinib Mesylate