title: Fabrication and characterization of non-enzymatic glucose sensor based on ternary NiO/CuO/polyaniline nanocomposite.
abstract: Novel nickel and copper oxide nanoparticle modified polyaniline (PANI) nanofibers (NiO/CuO/PANI) were fabricated and used as a non-enzymatic sensor for detecting glucose. PANI nanofibers were prepared through electrodeposition, whereas nickel and copper oxide nanoparticles were deposited on PANI nanofibers by electrodeposition and electrochemical oxidation in situ. The morphology and structure of NiO/CuO/PANI nanocomposites were characterized by field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), Raman spectroscopy, and Fourier transform infrared (FT-IR). The as-prepared NiO/CuO/PANI electrode was employed for non-enzymatic glucose detection in alkaline electrolyte and showed better electrocatalytic activity compared with the PANI, CuO/PANI, and NiO/PANI electrodes. Consequently, an amperometric electrode of glucose was achieved under 0.6 V versus Ag/AgCl with a wide linear range from 20 to 2500 μM (R(2) = 0.9978) and a low detection limit of 2.0 μM (signal/noise [S/N] = 3). This electrode can effectively analyze glucose concentration in human serum samples, avoiding interference, and is a promising non-enzymatic glucose sensor due to its low overpotential, high sensitivity, good selectivity and stability, fast response, and low cost.
authors.affiliation: Department of Chemistry, Faculty of Physics and Chemistry, School of Science, Alzahra University, Vanak, Tehran 1993891167, Iran. Electronic address: kh_ghanb@yahoo.com.
authors.forename: Kh
authors.initials: Kh
authors.lastname: Ghanbari
authors.affiliation: Department of Chemistry, Faculty of Physics and Chemistry, School of Science, Alzahra University, Vanak, Tehran 1993891167, Iran.
authors.forename: Z
authors.initials: Z
authors.lastname: Babaei
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D001786:Blood Glucose / Q000032:analysis*; D003300:Copper / Q000737:chemistry*; D006801:Humans; D008968:Molecular Conformation; D053761:Nanocomposites / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*
chemical_list: D000814:Aniline Compounds; D001786:Blood Glucose; C416807:polyaniline; D003300:Copper; D009532:Nickel; C028007:nickel monoxide; C000520:cuprous oxide
keywords: Copper oxide; Glucose sensor; Nickel oxide; Non-enzymatic; Polyaniline nanofiber