title: Comparative study of laparoscopic and mini-incision open donor nephrectomy: have we heard the last word in the debate?
abstract: OBJECTIVE
  Laparoscopic donor nephrectomy (LDN) is generally considered a better option than open donor nephrectomy (ODN) as it is associated with better cosmesis, less post-operative pain and faster recovery. Mini-incision donor nephrectomy (MDN) has proven to be an effective and less invasive modification of classic ODN. Our aim was to compare the peri-operative outcomes and quality of life of donors following laparoscopic and mini-incision ODN.
  
  
  METHODS
  One hundred patients, underwent donor nephrectomy using laparoscopic approach (n = 50) or open mini-incision approach (n = 50) over a period of 18 months. Data were entered into a prospective database and analyzed retrospectively.
  
  
  RESULTS
  The mean operative (skin to skin) time for MDN, 53.9 min (range, 40-75 min), was significantly shorter than the 93.7 min (range, 75-140 min) for LDN. The laparoscopic donors had a longer hospital stay, warm ischemia time and higher operative and post-operative cost. There was no significant difference in the pain scores, graft function, or quality of life between the two groups.
  
  
  CONCLUSIONS
  MDN compares well with the laparoscopic approach in terms of post-operative pain, graft function and quality of life of donors. Significantly less operative time along with the reduced cost makes it a better option in our predominantly lower BMI patient population.
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
authors.forename: Kunal
authors.initials: K
authors.lastname: Yadav
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Aggarwal
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Guleria
authors.affiliation: Department of Urology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
authors.forename: Rajeev
authors.initials: R
authors.lastname: Kumar
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D009392:Nephrectomy / Q000379:methods*; D011379:Prognosis; D011446:Prospective Studies; D011788:Quality of Life; D012189:Retrospective Studies; D055815:Young Adult
keywords: laparoscopic donor nephrectomy; live donor; mini-incision open donor nephrectomy; renal transplantation