title: Comparison of clinical and radiographic status around dental implants placed in patients with and without prediabetes: 1-year follow-up outcomes.
abstract: OBJECTIVE
  We hypothesized that peri-implant soft tissue inflammation is worse and peri-implant marginal bone loss (MBL) is higher around dental implants placed in patients with prediabetes compared to healthy subjects. The aim of the present 12-month follow-up study was to compare the clinical and radiographic status around dental implants placed in patients with and without prediabetes.
  
  
  METHODS
  Twelve patients with medically diagnosed prediabetes (Group-1) and 12 controls (Group-2) were included. All patients were indicated for single tooth maxillary or mandibular premolar replacement with the adjacent teeth intact. Success of the restored implants was assessed by comparing clinical (peri-implant bleeding on probing [BOP], and probing pocket depth [PPD]) and radiographic (peri-implant MBL) parameters at baseline and at 12-months follow-up. Statistical analysis was performed using one-way analysis of variance, and P-values <0.05 were considered statistically significant.
  
  
  RESULTS
  At 12 months of follow-up, there was no clinical evidence for the presence of plaque, BOP and peri-implant pockets with PPD ≥ 4 mm in both groups. At 12-month follow-up, the mean MBL among implants placed in groups 1 and 2 were 0.2 ± 0.1 mm and 0.1 ± 0.01 mm, respectively. Overall, the periodontal status (PI, BOP and PPD ≥ 4 mm) at 12-month follow-up was comparable among patients in both groups.
  
  
  CONCLUSIONS
  Within the limitations of this study, it is concluded that dental implants inserted in prediabetic and healthy patients have similar success rates and remain clinically and radiographically stable after 1-year follow-up.
authors.affiliation: Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Mohammad D
authors.initials: MD
authors.lastname: Al Amri
authors.affiliation: Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Tariq S
authors.initials: TS
authors.lastname: Abduljabbar
authors.affiliation: Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Abdulaziz A
authors.initials: AA
authors.lastname: Al-Kheraif
authors.affiliation: Department of Periodontology, School of Dental Medicine, Stony Brook University, Stony Brook, NY, USA.|Department of Oral Surgery and Implant Dentistry, Johann Wolfgang University, Frankfurt, Germany.
authors.forename: Georgios E
authors.initials: GE
authors.lastname: Romanos
authors.affiliation: Department of General Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, NY, USA.
authors.forename: Fawad
authors.initials: F
authors.lastname: Javed
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003758:Dental Implantation, Endosseous / Q000379:methods*; D019250:Dental Implants, Single-Tooth; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State; D011861:Radiography, Dental; D016896:Treatment Outcome
keywords: clinical parameters; dental implant; marginal bone loss; prediabetes; success rate