title: Atypical Presentation of Eosinophilic Fasciitis with Pitting Edema.
abstract: Eosinophilic fasciitis (EF) is a rare condition involving inflammation of the fascia and peripheral eosinophilia of unknown etiology leading to tissue fibrosis. Clinical presentation includes peripheral eosinophilia, symmetrical skin thickening with subcutaneous tissue induration of the extremities and rashes developing acutely over a period of days to weeks. An unusual feature of EF is the presence of symmetric pitting edema presumed to be secondary to vascular leakage. This is a case of eosinophilic fasciitis presenting in atypical fashion with pitting peripheral edema in addition to the classic symptoms.
authors.affiliation: John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI (C-WC).
authors.forename: Chih-Wei
authors.initials: CW
authors.lastname: Chang
authors.affiliation: John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI (C-WC).
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Lau
mesh_terms: D004487:Edema / Q000209:etiology / Q000473:pathology*; D004802:Eosinophilia / Q000150:complications / Q000473:pathology*; D005208:Fasciitis / Q000150:complications / Q000473:pathology*; D006801:Humans; D035002:Lower Extremity / Q000473:pathology*; D008297:Male; D008875:Middle Aged
keywords: Biopsy; Eosinophilic fasciitis; Pitting edema