title: [A Case of Long-Term Survival after Surgeries for Gastric Cancer and Metachronous Ovarian Metastasis].
abstract: The patient was a 57-year-old woman. In October 2011, she underwent distal gastrectomy, D2 lymphadenectomy, and Roux-en-Y reconstruction for gastric cancer (pT4a, pN3b, Stage ⅢC [JCGC 14th Edition]). She then received S-1 plus CDDP combination therapy and S-1 monotherapy as postoperative adjuvant chemotherapies for 1 year, and was followed up as an outpatient. In April 2013, a significant increase in the CA19-9 level was noted, and CT indicated a right ovarian tumor. Ovarian metastasis from the gastric cancer was diagnosed, and the response to 3 courses of weekly PTX was stable disease. No findings indicated metastasis to other organs. In July 2013, a salpingo-oophorectomy was performed, after which her CA19-9 level returned to the normal range. Follow-up was adopted as the postoperative strategy in part due to the desires of the patient. Presently, 3 years and 6 months after the initial surgery and 1 year and 9 months after the last surgery, no recurrence has been detected. Generally, ovarian metastasis from gastric cancer is considered to be associated with a poor prognosis. However, our patient showed long-term survival after surgeries for gastric cancer and asynchronous ovarian metastasis. Here, we report the details of our case and review the relevant literature.
authors.affiliation: Dept. of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yoshida
authors.forename: Naoki
authors.initials: N
authors.lastname: Wajima
authors.forename: Harue
authors.initials: H
authors.lastname: Akasaka
authors.forename: Shingo
authors.initials: S
authors.lastname: Sakuraba
authors.forename: Takahiro
authors.initials: T
authors.lastname: Muroya
authors.forename: Norihito
authors.initials: N
authors.lastname: Kubo
authors.forename: Kensuke
authors.initials: K
authors.lastname: Okano
authors.forename: Chiaki
authors.initials: C
authors.lastname: Uchida
authors.forename: Kenichi
authors.initials: K
authors.lastname: Hakamada
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D004338:Drug Combinations; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D010052:Ovariectomy; D010094:Oxonic Acid / Q000008:administration & dosage; D017239:Paclitaxel / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D017239:Paclitaxel; D002945:Cisplatin