title: High Speed Sub-GHz Spectrometer for Brillouin Scattering Analysis.
abstract: The goal of this protocol is to build a parallel high-extinction and high-resolution optical Brillouin spectrometer. Brillouin spectroscopy is a non-contact measurement method that can be used to obtain direct readouts of viscoelastic material properties. It has been a useful tool in material characterization, structural monitoring and environmental sensing. In the past, Brillouin spectroscopy has usually employed scanning Fabry-Perot etalons to perform spectral analysis. This process requires high illumination power and long acquisition times, making the technique unsuitable for biomedical applications. A recently introduced novel spectrometer overcomes this challenge by employing two VIPAs in a cross-axis configuration. This innovation enables sub-Gigahertz (GHz) resolution spectral analysis with sub-second acquisition time and illumination power within the safety limits of biological tissue. The multiple new applications facilitated by this improvement are currently being explored in biological research and clinical application.
authors.affiliation: Fischell Department of Bioengineering, University of Maryland.
authors.forename: Kim V
authors.initials: KV
authors.lastname: Berghaus
authors.affiliation: Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital; The Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology.
authors.forename: Seok H
authors.initials: SH
authors.lastname: Yun
authors.affiliation: Fischell Department of Bioengineering, University of Maryland; scarc@umd.edu.
authors.forename: Giuliano
authors.initials: G
authors.lastname: Scarcelli
mesh_terms: D004867:Equipment Design; D007834:Lasers; D008027:Light; D018613:Microscopy, Confocal / Q000295:instrumentation / Q000379:methods; D012542:Scattering, Radiation; D013057:Spectrum Analysis / Q000295:instrumentation* / Q000379:methods