title: Fast throughput determination of 21 allergenic disperse dyes from river water using reusable three-dimensional interconnected magnetic chemically modified graphene oxide followed by liquid chromatography-tandem quadrupole mass spectrometry.
abstract: We report the template-free fabrication of three-dimensional hierarchical nanostructures, i.e., three-dimensional interconnected magnetic chemically modified graphene oxide (3D-Mag-CMGO), through a simple and low-cost self-assembly process using one-pot reaction based on solvothermal method. The excellent properties of the 3D-Mag-CMGO are characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), vibrating sample magnetometer (VSM), FTIR, elementary analyzer (EA) and X-ray photoelectron spectroscopy (XPS). The easiness-to-handle of the magnetic dispersive solid phase extraction (Mag-dSPE) procedure is developed for preconcentration of 21 allergenic disperse dyes from river water. The obtained results show the higher extraction capacity of 3D-Mag-CMGO with recoveries between 80.0-112.0%. Furthermore, an ultra-fast liquid chromatography-tandem quadrupole mass spectrometry (UFLC-MS/MS) method for determination of 21 allergenic disperse dyes in river at sub-ppt levels has been developed with pretreatment of the samples by Mag-dSPE. The limits of quantification (LOQs) for the allergenic disperse dyes are between 0.57-34.05ng/L. Validation results on linearity, specificity, trueness and precision, as well as on application to the analysis of 21 allergenic disperse dyes in fifty real samples demonstrate the applicability to environment monitoring analysis.
authors.affiliation: Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of Zhejiang Province, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China; Ningbo Key Laboratory of Poison Research and Control, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China.
authors.forename: Yong-Gang
authors.initials: YG
authors.lastname: Zhao
authors.affiliation: Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of Zhejiang Province, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China; Ningbo Key Laboratory of Poison Research and Control, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China.
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Li
authors.affiliation: Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of Zhejiang Province, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China; Ningbo Key Laboratory of Poison Research and Control, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China.
authors.forename: Shan-Shan
authors.initials: SS
authors.lastname: Yao
authors.affiliation: School of Marine Sciences, Ningbo University, Ningbo, Zhejiang, 315211, China.
authors.forename: Ping-Ping
authors.initials: PP
authors.lastname: Zhan
authors.affiliation: Environment Monitoring Center of Changzhi, Changzhi, Shanxi, 046000, China.
authors.forename: Jun-Chao
authors.initials: JC
authors.lastname: Liu
authors.affiliation: Key Laboratory of Emergency Detection for Public Health of Zhejiang Province, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
authors.forename: Chang-Ping
authors.initials: CP
authors.lastname: Xu
authors.affiliation: Key Laboratory of Emergency Detection for Public Health of Zhejiang Province, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
authors.forename: Yi-Yu
authors.initials: YY
authors.lastname: Lu
authors.affiliation: Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of Zhejiang Province, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China; Ningbo Key Laboratory of Poison Research and Control, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China.
authors.forename: Xiao-Hong
authors.initials: XH
authors.lastname: Chen
authors.affiliation: Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of Zhejiang Province, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China; Ningbo Key Laboratory of Poison Research and Control, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, 315010, China. Electronic address: jmcjc@163.com.
authors.forename: Mi-Cong
authors.initials: MC
authors.lastname: Jin
mesh_terms: D000485:Allergens / Q000032:analysis*; D002853:Chromatography, Liquid; D004396:Coloring Agents / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods*; D006108:Graphite / Q000737:chemistry; D008280:Magnetics; D010087:Oxides / Q000737:chemistry*; D045483:Rivers / Q000737:chemistry*; D053719:Tandem Mass Spectrometry
chemical_list: D000485:Allergens; D004396:Coloring Agents; D010087:Oxides; D006108:Graphite
keywords: Allergenic disperse dyes; Enrichment; LC–MS/MS; Magnetic dispersive solid phase extraction; River water; Three-dimensional interconnected magnetic chemically modified graphene oxide