title: Use of Corynebacterium pseudodiphtheriticum for elimination of Staphylococcus aureus from the nasal cavity in volunteers exposed to abnormal microclimate and altered gaseous environment.
abstract: Effectiveness of saline suspension of Corynebacterium pseudodiphtheriticum containing spray was assessed in a 30-days chamber experiment modeling the effects of hyperthermia and polluted air on humans. Spray was targeted at eliminating Staphylococcus aureus from the nasal cavity of human subjects. Three of four volunteers became S. aureus carriers in the course of the experiment, and one was a chronic carrier of methicillin-resistant S. aureus (MRSA). Spray application eradicated S. aureus in three subjects and reduced its presence in the MRSA carrier. Results of the study suggest that C. pseudodiphtheriticum can be used for control of S. aureus in the nasal environment. However, further investigations are required.
authors.affiliation: Institute of Biomedical Problems, Khoroshevskoye shosse, 76A, 123007, Moscow, Russia. corallium@yandex.ru.
authors.forename: N V
authors.initials: NV
authors.lastname: Kiryukhina
authors.affiliation: International Science and Technology Center, Moscow, Russia.
authors.forename: V G
authors.initials: VG
authors.lastname: Melnikov
authors.affiliation: Institute of Biomedical Problems, Khoroshevskoye shosse, 76A, 123007, Moscow, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Suvorov
authors.affiliation: Institute of Biomedical Problems, Khoroshevskoye shosse, 76A, 123007, Moscow, Russia.
authors.forename: Yu A
authors.initials: YA
authors.lastname: Morozova
authors.affiliation: Institute of Biomedical Problems, Khoroshevskoye shosse, 76A, 123007, Moscow, Russia.
authors.forename: V K
authors.initials: VK
authors.lastname: Ilyin
keywords: Corynebacterium pseudodiphtheriticum; MRSA carrier; Microbial implantation; Probiotics; Staphylococcus aureus