title: Surgical therapy of single peri-implantitis intrabony defects, by means of deproteinized bovine bone mineral with 10% collagen.
abstract: OBJECTIVE
  To evaluate the efficacy of a reconstructive surgical procedure in single peri-implantitis infrabony defects.
  
  
  METHODS
  Seventy-five patients with one peri-implantitis crater-like lesion with pocket depth (PD) ≥ 6 mm, were included. Each defect was assigned to one characteristic class, by an independent examiner. After implant decontamination, defects were filled with deproteinized bovine bone mineral with 10% collagen.
  
  
  RESULTS
  At 1-year follow-up, four patients were lost and six implants removed. Treatment success, PD ≤ 5 mm and absence of suppuration/bleeding on probing (BOP), was obtained in 37 (52.1%) of the 71 implants examined. PD was significantly reduced by 2.92 ± 1.73 mm (p < 0.0001). BOP decreased from 71.5 ± 34.4% to 18.3 ± 28.6% (p < 0.0001). The mean number of deep pockets (≥ 6 mm) decreased from 3.00 ± 0.93 to 0.85 ± 1.35 (p < 0.0001).
  
  
  CONCLUSIONS
  These results confirm the possibility to successfully treat peri-implantitis lesions. There is lack of evidence of whether or not the resolution of the peri-implant disease is associated with the defect configuration. Due to the fact that complete resolution does not seem a predictable outcome, the clinical decision on whether implants should be treated should be based on several patient related elements.
authors.affiliation: Private practice, Torino, Italy.|Division of Maxillofacial Surgery, University of Torino, Torino, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Roccuzzo
authors.affiliation: Private practice, Torino, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Gaudioso
authors.affiliation: Private practice, Torino, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Lungo
authors.affiliation: Department of Public Health and Paediatrics, University of Torino, Torino, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Dalmasso
mesh_terms: D000818:Animals; D002417:Cattle; D003094:Collagen / Q000627:therapeutic use; D015921:Dental Implants; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000627:therapeutic use; D057873:Peri-Implantitis / Q000188:drug therapy; D019651:Plastic Surgery Procedures; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants; D008903:Minerals; D003094:Collagen
keywords: bone graft; bone substitute; defect configuration; non-submerged healing; peri-implantitis; surgical regenerative therapy