title: The Growing Spectrum of Cutaneous RASopathy.
abstract: Groesser et al. demonstrate that pyogenic granuloma is a RAS pathway-driven tumor. This important observation adds yet another manifestation to the growing spectrum of cutaneous "RASopathies" and raises intriguing questions about the relationship between RAS pathway activation and malignancy.
authors.affiliation: School of Medicine and School of Life Sciences, University of Dundee, Dundee, UK; Institute of Medical Biology, Singapore. Electronic address: m.vansteensel@dundee.ac.uk.
authors.forename: Maurice A M
authors.initials: MAM
authors.lastname: van Steensel
mesh_terms: D005260:Female; D011905:Genes, ras / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D017789:Granuloma, Pyogenic / Q000235:genetics*; D006801:Humans; D008297:Male; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics*; D012871:Skin Diseases / Q000235:genetics*
chemical_list: D048493:Proto-Oncogene Proteins B-raf