title: Non-high-density lipoprotein cholesterol: current status as cardiovascular marker.
abstract: OBJECTIVE
  In this review, we summarize the evidence with regard to the rationale of using nonhigh density lipoprotein cholesterol (non-HDL-C) as a cardiovascular disease (CVD) risk factor, in relation to low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (apoB).
  
  
  RESULTS
  In the 2015 National Lipid Association Annual Summary non-HDL-C is considered a coprimary target, apart from LDL-C. The other data published in the last 18 months about non-HDL-C support all the previous published data. There are no recent findings, which we deem to cause a change of the current opinion about non-HDL-C as a predictor for CVD.
  
  
  CONCLUSIONS
  The existing evidence supports the claim that non-HDL-C is superior to LDL-C in CVD risk estimation.
authors.affiliation: aDepartment of Vascular MedicinebDepartment of Cardiology, Academic Medical Center, Amsterdam, the Netherlands.
authors.forename: Rutger
authors.initials: R
authors.lastname: Verbeek
authors.forename: G Kees
authors.initials: GK
authors.lastname: Hovingh
authors.forename: S Matthijs
authors.initials: SM
authors.lastname: Boekholdt
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000378:metabolism*; D008076:Cholesterol, HDL / Q000378:metabolism*; D006801:Humans; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL