title: [A Case of Salvage Chemoradiotherapy for Regional Recurrence after Curative Esophagectomy].
abstract: We report a case of regional recurrence of esophageal cancer after curative esophagectomy. The patient has experienced long-term survival after treatment with salvage chemoradiotherapy (CRT). A 69-year-old woman had received esophagectomy for advanced thoracic esophageal cancer (pathological T3N1M0, Stage Ⅲ). Recurrence in the cervical regional lymph nodes was diagnosed 1 year 4 months after surgery. She was treated with salvage chemoradiotherapy consisting of 60 Gy radiation and cisplatin/5-fluorouracil. The metastatic lymph nodes disappeared(a complete response). She has been alive without recurrence for 7 years and 5 months since completing salvage CRT. Approximately 30-50% of patients develop recurrences of esophageal cancer after curative esophagectomy, and these patients rarely survive longer than a year. Therefore, it is important that we examine this rare case of long-term survival after recurrence of esophageal cancer.
authors.affiliation: Division of Gastrointestinal Surgery, Dept. of Surgery, Graduate School of Medicine, Kobe University.
authors.forename: Masashi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Okuno
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Imanishi
authors.forename: Shingo
authors.initials: S
authors.lastname: Kanaji
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Yamashita
authors.forename: Kiyonori
authors.initials: K
authors.lastname: Kanemitsu
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Sumi
authors.forename: Tetsu
authors.initials: T
authors.lastname: Nakamura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Kakeji
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D059248:Chemoradiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D004938:Esophageal Neoplasms / Q000473:pathology / Q000628:therapy*; D016629:Esophagectomy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008207:Lymphatic Metastasis; D012008:Recurrence; D016879:Salvage Therapy; D016896:Treatment Outcome
chemical_list: D002945:Cisplatin; D005472:Fluorouracil