title: Phytotoxic and Nematicidal Components of Lavandula luisieri.
abstract: Several preparations were obtained from the aerial parts of predomesticated Lavandula luisieri, including the essential oil and ethanolic, hexane, and ethyl acetate extractives. Additionally, pilot plant vapor pressure extraction was carried out at a pressure range of 0.5-1.0 bar to give a vapor pressure oil and an aqueous residue. A chemical study of the hexane extract led to the isolation of six necrodane derivatives (1, 2, and 4-7), with four of these (1, 2, 5, and 7) being new, as well as camphor, a cadinane sesquiterpene (9), tormentic acid, and ursolic acid. The EtOAc and EtOH extracts contained a mixture of phenolic compounds with rosmarinic acid being the major component. Workup of the aqueous residue resulted in the isolation of the necrodane 3 and (1R*,2S*,4R*)-p-menth-5-ene-1,2,8-triol (8), both new natural compounds. The structures of the new compounds were established based on their spectroscopic data. The phytotoxic and nematicidal activities of these compounds were evaluated.
authors.affiliation: Instituto de Ciencias Agrarias, Consejo Superior de Investigaciones Científicas , Serrano 115-bis, 28006 Madrid, Spain.
authors.forename: Luis F
authors.initials: LF
authors.lastname: Julio
authors.affiliation: Departamento de Química Orgánica, Instituto de Biotecnología, Universidad de Granada , Campus de Fuente Nueva, s/n, 18071 Granada, Spain.
authors.forename: Alejandro F
authors.initials: AF
authors.lastname: Barrero
authors.affiliation: Departamento de Química Orgánica, Instituto de Biotecnología, Universidad de Granada , Campus de Fuente Nueva, s/n, 18071 Granada, Spain.
authors.forename: M Mar
authors.initials: MM
authors.lastname: Herrador del Pino
authors.affiliation: CIQSO, Center for Research in Sustainable Chemistry and Department of Chemical Engineering, Physical Chemistry, and Organic Chemistry, Facultad de Ciencias Experimentales, Universidad de Huelva , Campus el Carmen, 21071 Huelva, Spain.
authors.forename: Jesús F
authors.initials: JF
authors.lastname: Arteaga
authors.affiliation: Departamento de Ciencia, Tecnología y Universidad, Centro de Investigación y Tecnología Agroalimentaria de Aragón, Gobierno de Aragón , Avenida Montañana, 930, Zaragoza, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Burillo
authors.affiliation: Instituto de Ciencias Agrarias, Consejo Superior de Investigaciones Científicas , Serrano 115-bis, 28006 Madrid, Spain.
authors.forename: Maria Fe
authors.initials: MF
authors.lastname: Andres
authors.affiliation: Instituto de Productos Naturales y Agrobiología, Consejo Superior de Investigaciones Científicas , Avenida Astrofísico F. Sánchez, 3, 38206 La Laguna, Tenerife, Spain.
authors.forename: Carmen E
authors.initials: CE
authors.lastname: Díaz
authors.affiliation: Instituto de Ciencias Agrarias, Consejo Superior de Investigaciones Científicas , Serrano 115-bis, 28006 Madrid, Spain.
authors.forename: Azucena
authors.initials: A
authors.lastname: González-Coloma
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D000969:Antinematodal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001042:Aphids / Q000187:drug effects; D027523:Lavandula / Q000737:chemistry; D015394:Molecular Structure; D039821:Monoterpenes; D019906:Nuclear Magnetic Resonance, Biomolecular; D009822:Oils, Volatile / Q000032:analysis; D035261:Plant Components, Aerial / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013030:Spain; D018411:Spodoptera / Q000187:drug effects; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D014315:Triterpenes / Q000302:isolation & purification; D000097245:Ursolic Acid
chemical_list: D000890:Anti-Infective Agents; D000969:Antinematodal Agents; D039821:Monoterpenes; D009822:Oils, Volatile; D012717:Sesquiterpenes; D013729:Terpenes; D014315:Triterpenes; D000097245:Ursolic Acid; C000608901:(1R*,2S*,4R*)-p-menth-5-ene-1,2,8-triol; C007695:euscaphic acid