title: Contrast-Induced Acute Kidney Injury: An Update.
abstract: Contrast-induced acute kidney injury (CI-AKI) is defined as an abrupt deterioration in renal function associated with the administration of iodinated contrast media. This type of acute kidney injury is frequently encountered as a complication of percutaneous coronary intervention (PCI) and is associated with adverse short- and long-term outcomes including mainly mortality, cardiovascular morbidity and prolongation of hospitalization. The incidence of CI-AKI after PCI ranges from 2 to 20 % according to baseline kidney function. It may also range according to the clinical setting, being higher after emergency PCI. The primary manifestation is a small decline in kidney function, occurring 1 to 3 days after the procedure. Kidney function usually returns to preexisting levels within 7 days. Incidence of acute renal failure requiring dialysis following PCI is rare (<1 %). The present article aims to review up-to-date published data concerning diagnosis, definition, epidemiology and prognosis of this novel in-hospital epidemic.
authors.affiliation: University Cardiology Department, Medical School, Democritus University of Thrace, Dragana, GR-68131, Alexandroupolis, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Chalikias
authors.affiliation: University Cardiology Department, Medical School, Democritus University of Thrace, Dragana, GR-68131, Alexandroupolis, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Drosos
authors.affiliation: University Cardiology Department, Medical School, Democritus University of Thrace, Dragana, GR-68131, Alexandroupolis, Greece. dtziakas@med.duth.gr.
authors.forename: Dimitrios N
authors.initials: DN
authors.lastname: Tziakas
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D002318:Cardiovascular Diseases / Q000150:complications; D003287:Contrast Media / Q000009:adverse effects*; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007668:Kidney / Q000187:drug effects; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects; D011379:Prognosis
chemical_list: D003287:Contrast Media
keywords: Acute kidney injury; Contrast induced nephropathy; Contrast media; Percutaneous coronary intervention