title: "Big Data" Gets Personal.
abstract: A woman at-risk for a rare fatal prion disease retrained in science with her husband and joined a bioinformatics team to analyze shared data, providing insights about variant penetrance and possible treatments (Minikel et al., this issue).
authors.affiliation: Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, U.S.A. Harvard Medical School, Boston, MA 02115, U.S.A. Partners HealthCare Personalized Medicine, Boston, MA 02115, U.S.A.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Lebo
authors.affiliation: Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, U.S.A.
authors.forename: Sheila
authors.initials: S
authors.lastname: Sutti
authors.affiliation: Harvard Medical School, Boston, MA 02115, U.S.A. Partners HealthCare Personalized Medicine, Boston, MA 02115, U.S.A. Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, U.S.A. Broad Institute of MIT and Harvard, Boston, MA 02115, U.S.A. rcgreen@genetics.med.harvard.edu.
authors.forename: Robert C
authors.initials: RC
authors.lastname: Green
mesh_terms: D019295:Computational Biology; D017096:Prion Diseases; D011328:Prions; D035583:Rare Diseases; D012586:Science
chemical_list: D011328:Prions