title: Information Technology Support for Clinical Genetic Testing within an Academic Medical Center.
abstract: Academic medical centers require many interconnected systems to fully support genetic testing processes. We provide an overview of the end-to-end support that has been established surrounding a genetic testing laboratory within our environment, including both laboratory and clinician facing infrastructure. We explain key functions that we have found useful in the supporting systems. We also consider ways that this infrastructure could be enhanced to enable deeper assessment of genetic test results in both the laboratory and clinic.
authors.affiliation: Partners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. saronson@partners.org.|Partners HealthCare Research Computing, 65 Landsdowne Street, Cambridge, MA 02139, USA. saronson@partners.org.
authors.forename: Samuel
authors.initials: S
authors.lastname: Aronson
authors.affiliation: Partners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. lmahanta@partners.org.
authors.forename: Lisa
authors.initials: L
authors.lastname: Mahanta
authors.affiliation: Partners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. lhros@partners.org.|Partners HealthCare Research Computing, 65 Landsdowne Street, Cambridge, MA 02139, USA. lhros@partners.org.
authors.forename: Lei Lei
authors.initials: LL
authors.lastname: Ros
authors.affiliation: Partners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. ehclark@partners.org.|Partners HealthCare Research Computing, 65 Landsdowne Street, Cambridge, MA 02139, USA. ehclark@partners.org.
authors.forename: Eugene
authors.initials: E
authors.lastname: Clark
authors.affiliation: Partners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. lbabb@geneinsight.com.|Partners HealthCare Research Computing, 65 Landsdowne Street, Cambridge, MA 02139, USA. lbabb@geneinsight.com.
authors.forename: Lawrence
authors.initials: L
authors.lastname: Babb
authors.affiliation: Partners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. mfoates@partners.org.|Partners HealthCare Research Computing, 65 Landsdowne Street, Cambridge, MA 02139, USA. mfoates@partners.org.
authors.forename: Michael
authors.initials: M
authors.lastname: Oates
authors.affiliation: Partners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. hrehm@partners.org.|Department of Pathology, Brigham &amp; Women's Hospital, Boston, MA 02115, USA. hrehm@partners.org.|Department of Pathology, Harvard Medical School, Boston, MA 02115, USA. hrehm@partners.org.|The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. hrehm@partners.org.
authors.forename: Heidi
authors.initials: H
authors.lastname: Rehm
authors.affiliation: Partners HealthCare Personalized Medicine, 65 Landsdowne Street, Cambridge, MA 02139, USA. mlebo@partners.org.|Department of Pathology, Brigham &amp; Women's Hospital, Boston, MA 02115, USA. mlebo@partners.org.|Department of Pathology, Harvard Medical School, Boston, MA 02115, USA. mlebo@partners.org.
authors.forename: Matthew
authors.initials: M
authors.lastname: Lebo
keywords: GIGPAD; GeneInsight; LIMS; LIS; genetic testing process; information technology support