title: Applying the miniaturization technologies for biosensor design.
abstract: Microengineering technologies give us some opportunities in developing high-tech sensing systems that operate with low volumes of samples, integrates one or more laboratory functions on a single substrate, and enables automation. These millimetric sized devices can be produced for only a few dollars, which makes them promising candidates for mass-production. Besides electron beam lithography, stencil lithography, nano-imprint lithography or dip pen lithography, basic photolithography is the technique which is extensively used for the design of microengineered sensing systems. This technique has some advantages such as easy-to-manufacture, do not require expensive instrumentation, and allow creation of lower micron-sized patterns. In this review, it has been focused on three different type of microengineered sensing devices which are developed using micro/nano-patterning techniques, microfluidic technology, and microelectromechanics system based technology.
authors.affiliation: Department of Chemistry, Science Faculty, Ankara University, Tandoğan, Ankara 06100, Turkey. Electronic address: burakderkus@gmail.com.
authors.forename: Burak
authors.initials: B
authors.lastname: Derkus
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation* / Q000379:methods; D046208:Microchip Analytical Procedures / Q000379:methods*; D008904:Miniaturization / Q000295:instrumentation / Q000379:methods*
keywords: MEMs; Microfluidics; Micropatterning; Microtechnology; Miniaturization; Nanopatterning; Nanotechnology