title: A systematic review of interventions to reduce hospitalisation in Parkinson's disease.
abstract: The neurodegenerative process in Parkinson's disease (PD) results in a relentless progression of motor and non-motor symptoms. Affected individuals are frequently hospitalised for complications of the disease including falls, fractures, infections, and neuropsychiatric symptoms. When admitted to hospital, inpatient care is often suboptimal as it focusses on the primary cause of admission, and is associated with poor patient outcomes and significant healthcare costs.
  
  
  OBJECTIVE
  To review existing literature for evidence-based interventions aimed at reducing hospital admissions in PD.
  
  
  METHODS
  Electronic literature search in EMBASE, MEDLINE and CINAHL databases for studies evaluating interventions to reduce hospital admissions in PD. We included publications with full abstracts, published in the English language and addressing interventions to reduce hospital admissions in PD.
  
  
  RESULTS
  To date there are no randomised controlled trials addressing the topic. We identified nine relevant retrospective studies. Results from these studies suggest an association between frequent neurologist consultations, open access clinics, and medication compliance with a reduction in PD hospital admissions and emergency room visits.
  
  
  CONCLUSIONS
  This systematic review highlights the lack of robust evidence for measures aimed at reducing hospital admissions in people with PD. Future prospective studies are required to evaluate the effectiveness of proposed interventions.
authors.affiliation: School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, UK; University Hospital Birmingham Foundation Trust, Birmingham, UK. Electronic address: shammuzerengi@yahoo.com.
authors.forename: S
authors.initials: S
authors.lastname: Muzerengi
authors.affiliation: Birmingham Clinical Trials Unit, School of Health & Population Sciences, University of Birmingham, UK.
authors.forename: C
authors.initials: C
authors.lastname: Herd
authors.affiliation: Birmingham Clinical Trials Unit, School of Health & Population Sciences, University of Birmingham, UK.
authors.forename: C
authors.initials: C
authors.lastname: Rick
authors.affiliation: School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, UK; Birmingham Clinical Trials Unit, School of Health & Population Sciences, University of Birmingham, UK; Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
authors.forename: C E
authors.initials: CE
authors.lastname: Clarke
mesh_terms: D006760:Hospitalization; D006801:Humans; D010300:Parkinson Disease / Q000628:therapy*
keywords: Hospitalisation; Interventions; Parkinson's disease; Randomised controlled trial