title: Blood pressure response to acute and chronic exercise in chronic kidney disease.
abstract: OBJECTIVE
  The current study was designed to determine if a relationship exists between acute and chronic blood pressure responses to aerobic exercise in pre-dialysis patients.
  
  
  METHODS
  Pre-dialysis kidney patients attended four sessions before being randomized to the treatment (n = 25) or control group (n = 21). In session 1, resting blood pressure was recorded, and these measurements were repeated during the second visit when peak oxygen uptake (VO2peak) was assessed. In the third and fourth sessions, blood pressures were taken prior to a 40 min walk or period of seated rest. After the 40 min walk or seated rest, blood pressures were monitored for 60 min in the laboratory and for the subsequent 24 h. After session 4, subjects in the treatment group trained aerobically at a moderate intensity, three times per week for 16 weeks. Control subjects were asked to be sedentary. All measurements were repeated after 16 weeks of training or sedentary living.
  
  
  RESULTS
  Training increased VO2peak(mL/kg per minute) in the treatment group (baseline 19.6 ± 6.7 vs 21.2 ± 7.7, P < 0.05), with no change in the control (18.0 ± 6.0 vs 17.5 ± 5.7) group. Post-exercise hypotension occurred at baseline prior to training but was unaffected by 16 weeks of training.
  
  
  CONCLUSIONS
  Post-exercise hypotension occurs in pre-dialysis patients following aerobic exercise, but short-term moderate-intensity continuous aerobic training has no effect upon this response. There seems to be no relationship between the acute and chronic blood pressure responses to exercise in pre-dialysis kidney patients.
authors.affiliation: Springfield College, Springfield, Massachusetts, USA.
authors.forename: Samuel
authors.initials: S
authors.lastname: Headley
authors.affiliation: Renal and Transplant Associates of New England, Springfield, Massachusetts, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Germain
authors.affiliation: Springfield College, Springfield, Massachusetts, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Wood
authors.affiliation: Springfield College, Springfield, Massachusetts, USA.
authors.forename: Jyovani
authors.initials: J
authors.lastname: Joubert
authors.affiliation: Springfield College, Springfield, Massachusetts, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Milch
authors.affiliation: Springfield College, Springfield, Massachusetts, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Evans
authors.affiliation: Universities of the Rockies, Colorado, USA.
authors.forename: Allen
authors.initials: A
authors.lastname: Cornelius
authors.affiliation: Springfield College, Springfield, Massachusetts, USA.
authors.forename: Britton
authors.initials: B
authors.lastname: Brewer
authors.affiliation: University of Hartford, West Hartford, Connecticut, USA.
authors.forename: Beth
authors.initials: B
authors.lastname: Taylor
authors.affiliation: University of Connecticut, Mansfield, Connecticut, USA.
authors.forename: Linda S
authors.initials: LS
authors.lastname: Pescatello
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm; D005081:Exercise Therapy / Q000009:adverse effects / Q000379:methods*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007022:Hypotension / Q000209:etiology / Q000503:physiopathology; D007668:Kidney / Q000503:physiopathology; D008297:Male; D008404:Massachusetts; D008875:Middle Aged; D010101:Oxygen Consumption; D010807:Physical Endurance; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D057185:Sedentary Behavior; D013997:Time Factors; D016896:Treatment Outcome; D016138:Walking
keywords: aerobic training; ambulatory blood pressure; hypertension; moderate intensity; post-exercise hypotension