title: A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis.
abstract: Immunoglobulin G4 (IgG4)-related disease is an emerging new clinicopathological disorder that is characterized by elevation of serum IgG4 levels and histological findings of IgG4-positive plasmacytic infiltration. IgG4-related disease may appear synchronously or metachronously in a wide variety of organs. The current patient was found to have pericardial effusion and retroperitoneal fibrosis. He was subsequently diagnosed with coronary artery stenosis. (18)F-FDG positron emission tomography showed enhanced FDG uptake in lymph nodes as well as pericardial and peri-aortic tissue. Histopathology of the mediastinal lymph node showed the infiltration of numerous IgG4-positive cells, leading to the diagnosis of IgG4-related lymphadenopathy with pericardial and periarterial involvement.
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
authors.forename: Ryoto
authors.initials: R
authors.lastname: Hourai
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Miyamura
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
authors.forename: Ryunosuke
authors.initials: R
authors.lastname: Tasaki
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Iwata
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Takeda
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Morita
authors.affiliation: Department of Thoracic Surgery, Osaka Medical College, Osaka, Japan.
authors.forename: Nobuharu
authors.initials: N
authors.lastname: Hanaoka
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Tanigawa
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan.
authors.forename: Kensaku
authors.initials: K
authors.lastname: Shibata
authors.affiliation: Department of Pathology, Osaka Medical College, Osaka, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takeshita
authors.affiliation: Division of Rheumatology, Department of Internal Medicine, Kanazawa University Hospital, Kanazawa, Japan.
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Kawano
authors.affiliation: Department of Pathology, Okayama University Graduate School of Medicine, Okayama, Japan.
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Sato
authors.affiliation: Department of Pathology, Osaka Medical College, Osaka, Japan.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Hirose
authors.affiliation: Department of Cardiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, 569-8686, Japan. ishizaka@osaka-med.ac.jp.
authors.forename: Nobukazu
authors.initials: N
authors.lastname: Ishizaka
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000368:Aged; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging*; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D004322:Drainage / Q000379:methods; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D000072281:Lymphadenopathy / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D010493:Pericarditis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D010496:Pericardium / Q000473:pathology; D010996:Pleural Effusion / Q000628:therapy*; D000072078:Positron Emission Tomography Computed Tomography
chemical_list: D000305:Adrenal Cortex Hormones; D007074:Immunoglobulin G
keywords: Cardiovascular system; IgG4-related disease; Lymphadenopathy