title: Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace.
abstract: Complex biomedical analyses require the use of multiple software tools in concert and remain challenging for much of the biomedical research community. We introduce GenomeSpace (http://www.genomespace.org), a cloud-based, cooperative community resource that currently supports the streamlined interaction of 20 bioinformatics tools and data resources. To facilitate integrative analysis by non-programmers, it offers a growing set of 'recipes', short workflows to guide investigators through high-utility analysis tasks.
authors.affiliation: Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, USA.
authors.forename: Kun
authors.initials: K
authors.lastname: Qu
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
authors.forename: Sara
authors.initials: S
authors.lastname: Garamszegi
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
authors.forename: Felix
authors.initials: F
authors.lastname: Wu
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
authors.forename: Helga
authors.initials: H
authors.lastname: Thorvaldsdottir
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.|Department of Medicine, University of California, San Diego, La Jolla, USA.
authors.forename: Ted
authors.initials: T
authors.lastname: Liefeld
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.|Department of Medicine, University of California, San Diego, La Jolla, USA.
authors.forename: Marco
authors.initials: M
authors.lastname: Ocana
authors.affiliation: Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
authors.forename: Diego
authors.initials: D
authors.lastname: Borges-Rivera
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.|Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Pochet
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.|Department of Medicine, University of California, San Diego, La Jolla, USA.
authors.forename: James T
authors.initials: JT
authors.lastname: Robinson
authors.affiliation: Department of Medicine, University of California, San Diego, La Jolla, USA.
authors.forename: Barry
authors.initials: B
authors.lastname: Demchak
authors.affiliation: Department of Medicine, University of California, San Diego, La Jolla, USA.
authors.forename: Tim
authors.initials: T
authors.lastname: Hull
authors.affiliation: Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.|Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Gil
authors.initials: G
authors.lastname: Ben-Artzi
authors.affiliation: Department of Biochemistry and Molecular Biology, Penn State University, University Park, PA, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Blankenberg
authors.affiliation: UC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA.
authors.forename: Galt P
authors.initials: GP
authors.lastname: Barber
authors.affiliation: UC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA.
authors.forename: Brian T
authors.initials: BT
authors.lastname: Lee
authors.affiliation: UC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Kuhn
authors.affiliation: Department of Biochemistry and Molecular Biology, Penn State University, University Park, PA, USA.
authors.forename: Anton
authors.initials: A
authors.lastname: Nekrutenko
authors.affiliation: Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Eran
authors.initials: E
authors.lastname: Segal
authors.affiliation: Department of Medicine, University of California, San Diego, La Jolla, USA.
authors.forename: Trey
authors.initials: T
authors.lastname: Ideker
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.|Department of Medicine, University of California, San Diego, La Jolla, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Reich
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.|Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.|Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.
authors.forename: Aviv
authors.initials: A
authors.lastname: Regev
authors.affiliation: Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, USA.|Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
authors.forename: Howard Y
authors.initials: HY
authors.lastname: Chang
authors.affiliation: The Broad Institute of MIT and Harvard, Cambridge, MA, USA.|Department of Medicine, University of California, San Diego, La Jolla, USA.
authors.forename: Jill P
authors.initials: JP
authors.lastname: Mesirov
mesh_terms: D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods*; D019295:Computational Biology / Q000379:methods*; D057225:Data Mining; D030541:Databases, Genetic; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D020407:Internet; D012984:Software; D018511:Systems Integration