title: Primary tracheobronchial non-Hodgkin lymphoma causing life-threatening airway obstruction: a case report.
abstract: Primary tracheobronchial non-Hodgkin lymphoma (NHL) is a rare tracheobronchial tumor that typically presents as an endobronchial mass and/or mucosal infiltration together with lymphadenopathy. Here we report a case of primary tracheobronchial NHL which was confirmed by histopathological analysis of the endobronchial biopsy specimens. We initially could not treat with chemotherapy because the life-threatening obstruction of the bilateral main bronchi caused by NHL. After interventional bronchoscopy involving cryotherapy, electrocautery and argon plasma coagulation to successfully alleviate airway obstruction, we were able to administer chemotherapy, which elicited a good response. This case illustrates that NHL should be considered in the differential diagnosis of central airway obstruction. Interventional bronchoscopy is an effective method to alleviate airway obstruction in primary tracheobronchial NHL and prepare the patient to receive tumor-specific chemotherapy and other treatments.
authors.affiliation: 1 Institute of Respiratory Disease, 2 Department of Hematology, the First Hospital of China Medical University, Shenyang 110001, China ; 3 Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.
authors.forename: Fang-Fei
authors.initials: FF
authors.lastname: Yang
authors.affiliation: 1 Institute of Respiratory Disease, 2 Department of Hematology, the First Hospital of China Medical University, Shenyang 110001, China ; 3 Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.
authors.forename: Ran
authors.initials: R
authors.lastname: Gao
authors.affiliation: 1 Institute of Respiratory Disease, 2 Department of Hematology, the First Hospital of China Medical University, Shenyang 110001, China ; 3 Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Miao
authors.affiliation: 1 Institute of Respiratory Disease, 2 Department of Hematology, the First Hospital of China Medical University, Shenyang 110001, China ; 3 Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.
authors.forename: Xiao-Jing
authors.initials: XJ
authors.lastname: Yan
authors.affiliation: 1 Institute of Respiratory Disease, 2 Department of Hematology, the First Hospital of China Medical University, Shenyang 110001, China ; 3 Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Hou
authors.affiliation: 1 Institute of Respiratory Disease, 2 Department of Hematology, the First Hospital of China Medical University, Shenyang 110001, China ; 3 Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.affiliation: 1 Institute of Respiratory Disease, 2 Department of Hematology, the First Hospital of China Medical University, Shenyang 110001, China ; 3 Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.
authors.forename: Qiu-Yue
authors.initials: QY
authors.lastname: Wang
authors.affiliation: 1 Institute of Respiratory Disease, 2 Department of Hematology, the First Hospital of China Medical University, Shenyang 110001, China ; 3 Department of Pathology, the First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Kang
keywords: Lymphoma; airway obstruction; bronchoscopy; cryotherapy