title: Immunoglobulin G4-Related Sclerosing Disease Manifesting as Bilateral Tonsillar Hypertrophy on MR Images: A Case Report.
abstract: Immunoglobulin G4-related sclerosing disease (IgG4-SD) is currently recognized as a distinct systemic disease involving various organs. We reported the imaging findings of a case of pathologically confirmed IgG4-SD involving bilateral palatine tonsils. CT and MRI showed diffuse enlargement of both palatine tonsils with homogeneous contrast enhancement. Focal contour bulging was noted in the right palatine tonsil. Lesions appeared as isointense on T1-weighted and slightly hyperintense on T2-weighted MRI images, as compared with muscle. The T2-weighted MRI image showed a striated pattern in both tonsils. Despite its rare occurrence, IgG4-SD should be included in the differential diagnoses of patients with symptomatic bilateral tonsillar hypertrophy that is non-responsive to medication.
authors.affiliation: Department of Radiology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul 07441, Korea.
authors.forename: Mee Hyun
authors.initials: MH
authors.lastname: Park
authors.affiliation: Department of Radiology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul 07441, Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Woo
authors.affiliation: Department of Radiology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul 07441, Korea.
authors.forename: Yul
authors.initials: Y
authors.lastname: Lee
authors.affiliation: Department of Radiology, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul 05355, Korea.
authors.forename: Dae Young
authors.initials: DY
authors.lastname: Yoon
authors.affiliation: Department of Radiology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul 07441, Korea.
authors.forename: Hye Sook
authors.initials: HS
authors.lastname: Hong
authors.affiliation: Department of Pathology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul 07441, Korea.
authors.forename: Min Eui
authors.initials: ME
authors.lastname: Hong
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000473:pathology; D007074:Immunoglobulin G / Q000276:immunology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D014066:Palatine Tonsil / Q000473:pathology*; D012189:Retrospective Studies; D012598:Sclerosis / Q000175:diagnosis / Q000473:pathology*
chemical_list: D007074:Immunoglobulin G
keywords: IgG4-related sclerosing disease; MRI; Palatine tonsil