title: Agminated cellular blue naevi of the penis: dermoscopic, confocal and histopathological correlation of two cases.
abstract: Blue naevi may present rarely as multiple lesions grouped in a circumscribed area, described as agminated blue naevi. This clinical presentation may mimic metastatic malignant melanoma. We present two cases of agminated cellular blue naevi of the penis, with dermoscopy, reflectance confocal microscopy and histopathological correlation. Dermoscopy of the area showed multiple grouped lesions of homogeneous dark-brown to blue colour. Using reflectance confocal microscopy, focusing on the bluish areas, predominantly bright dendritic cells were visible at the dermoepidermal junction and papillary dermis, while in the brownish areas the presence of dendritic and bright cells predominated in the basal layer. Our patients are of special interest as they are the first cases, to our knowledge, reported of agminated blue naevi on the penis, studied by both dermoscopy and confocal microscopy, confirming the diagnosis with histopathological correlation. Moreover, one case represented a divided or 'kissing' blue naevus of the penis.
authors.affiliation: Dermatology Department, Melanoma Unit, Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain.|Dermatology Department, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.
authors.forename: H
authors.initials: H
authors.lastname: Collgros
authors.affiliation: Dermatology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Vicente
authors.affiliation: Pathology Department, Melanoma Unit, IDIBAPS, Barcelona, Spain.
authors.forename: A M
authors.initials: AM
authors.lastname: Díaz
authors.affiliation: Pathology Department, Melanoma Unit, IDIBAPS, Barcelona, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Rodríguez-Carunchio
authors.affiliation: Dermatology Department, Melanoma Unit, Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain.|Universitat de Barcelona, Barcelona, Spain.|Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER), Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Malvehy
authors.affiliation: Dermatology Department, Melanoma Unit, Hospital Clínic de Barcelona, IDIBAPS, Barcelona, Spain.|Universitat de Barcelona, Barcelona, Spain.|Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER), Barcelona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Puig
mesh_terms: D000293:Adolescent; D000368:Aged; D046169:Dermoscopy; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D018329:Nevus, Blue / Q000473:pathology*; D010412:Penile Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*