title: Frequency of pediatric migraine with aura in a clinic-based sample.
abstract: OBJECTIVE
  To assess the prevalence and risk factors for pediatric migraine with aura (MWA) among patients presenting to pediatric neurology clinics.
  
  
  BACKGROUND
  Headache is a common complaint among children, and the prevalence of migraine is about 8%. Up to one third of adults with migraine report experiencing aura; however, the exact percentage in children is unknown.
  
  
  METHODS
  Medical records of children presenting with headache to three pediatric neurology clinics in Haifa in the last 5 years were retrospectively reviewed. Inclusion criteria were a diagnosis of migraine headache at 5-18 years of age.
  
  
  RESULTS
  Of 260 children (140 female) who had migraine, 26.2% experienced aura. MWA was more common among females compared to males (32.6% vs 18.9%, P < .01) and among older children (OR: 2.50, 95% CI: 1.20-5.20; P < .01). Among those who experienced aura, visual aura was more common in females than males (66.7% vs 33.3%, P < .04). Family history of migraine was strongly related to MWA (P < .02): the odds of MWA were 2.46 times greater in children who had a family history of migraine. (OR: 2.46, 95% CI: 1.08-5.62; P < .03).
  
  
  CONCLUSIONS
  MWA is as common in children as in adults. Aura is more common in older children. Children who have MWA are more likely to have a family history of migraine.
authors.affiliation: Department of Pediatrics, Bnai Zion Medical Center, Haifa, Israel.|Pediatric Neurology Unit, Bnai Zion Medical Center, Haifa, Israel.|Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel.
authors.forename: Jacob
authors.initials: J
authors.lastname: Genizi
authors.affiliation: Department of Pediatrics, Bnai Zion Medical Center, Haifa, Israel.
authors.forename: Amal
authors.initials: A
authors.lastname: Khourieh Matar
authors.affiliation: Pediatric Neurology Unit, Carmel Medical Center, Haifa, Israel.|Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel.
authors.forename: Nathanel
authors.initials: N
authors.lastname: Zelnik
authors.affiliation: Child Development & Pediatric Neurology Service, Meuhedet - Northern Region, Haifa, Israel.
authors.forename: Mitchell
authors.initials: M
authors.lastname: Schertz
authors.affiliation: Department of Pediatrics, Bnai Zion Medical Center, Haifa, Israel.|Bruce and Ruth Rappaport Faculty of Medicine, Technion, Haifa, Israel.
authors.forename: Isaac
authors.initials: I
authors.lastname: Srugo
mesh_terms: D000293:Adolescent; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D005260:Female; D006776:Hospitals, Pediatric / Q000706:statistics & numerical data*; D006801:Humans; D007557:Israel / Q000453:epidemiology; D008297:Male; D020325:Migraine with Aura / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors
keywords: adolescents; aura; children; headache; migraine; prevalence