title: Nontrauma open abdomens: A prospective observational study.
abstract: BACKGROUND
  Damage-control surgery with open abdomen (OA) is described for trauma, but little exists regarding use in the emergency general surgery. This study aimed to better define the following: demographics, indications for surgery and OA, fascial and surgical site complications, and in-hospital/long-term mortality. We hypothesize that older patients will have increased mortality, patients will have protracted stays, they will require specialized postdischarge care, and the indications for OA will be varied.
  
  
  METHODS
  A prospective observational study of emergency general surgery OA patients from June 2013 to June 2014 was performed. Demographics, clinical/operative variables, comorbidities, indications for procedure and OA, wound/fascial complications, and disposition were collected. Patients were stratified into age groups (≤ 60, 61-79, and ≥ 80 years). Six-month and 1-year mortality was determined by query of the Social Security Death Index.
  
  
  RESULTS
  A total of 338 laparotomies were performed, of which 96 (28%) were managed with an OA. Median age was 61 years (interquartile range [IQR], 0-68 years), and 51% were male. The median Charlson Comorbidity Index was 2 (IQR, 1.5-5.1), and the median hospital stay was 25 days (IQR, 15-50 days). The most common indications for operation were perforated viscus/free air (20%), mesenteric ischemia (17%), peritonitis (16%), and gastrointestinal hemorrhage (12%). The most common indication for OA was damage control (37%). In the 63 patients with fascial closure, there were 9 (14%) wound infections and 6 (10%) fascial dehiscences. A total of 30% of the patients died in the hospital, and an additional six patients died 6 months after discharge. Patients in the oldest age stratum were more likely to die at 6 months than those in the lower strata.
  
  
  CONCLUSIONS
  Older patients were more likely to die by 6 months, the median hospital stay was 3 weeks, and there were multiple indications for OA management. With a 6-month mortality of 36% and 70% of survivors requiring postdischarge care, this population represents a critically ill population meriting additional study.
  
  
  METHODS
  Prognostic and epidemiologic study, level III.
authors.affiliation: From the University of Maryland, R Adams Cowley Shock Trauma Center, Baltimore, Maryland.
authors.forename: Brandon R
authors.initials: BR
authors.lastname: Bruns
authors.forename: Sarwat A
authors.initials: SA
authors.lastname: Ahmad
authors.forename: Lindsay
authors.initials: L
authors.lastname: OʼMeara
authors.forename: Ronald
authors.initials: R
authors.lastname: Tesoriero
authors.forename: Margaret
authors.initials: M
authors.lastname: Lauerman
authors.forename: Elena
authors.initials: E
authors.lastname: Klyushnenkova
authors.forename: Rosemary
authors.initials: R
authors.lastname: Kozar
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Scalea
authors.forename: Jose J
authors.initials: JJ
authors.lastname: Diaz
mesh_terms: D000007:Abdominal Injuries / Q000401:mortality / Q000601:surgery*; D000368:Aged; D015897:Comorbidity; D004630:Emergencies; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007813:Laparotomy; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015996:Survival Rate; D016896:Treatment Outcome