title: Prosthetic joint infection due to Lysobacter thermophilus diagnosed by 16S rRNA gene sequencing.
abstract: We report the first case of prosthetic joint infection caused by Lysobacter thermophilus which was identified by 16S rRNA gene sequencing. Removal of prosthesis followed by antibiotic treatment resulted in good clinical outcome. This case illustrates the use of molecular diagnostics to detect uncommon organisms in suspected prosthetic infections.
authors.affiliation: Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: B
authors.initials: B
authors.lastname: Dhawan
authors.forename: S
authors.initials: S
authors.lastname: Sebastian
authors.forename: R
authors.initials: R
authors.lastname: Malhotra
authors.forename: A
authors.initials: A
authors.lastname: Kapil
authors.forename: D
authors.initials: D
authors.lastname: Gautam
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001168:Arthritis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D003646:Debridement; D005260:Female; D020459:Genes, rRNA; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D006801:Humans; D053528:Lysobacter / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D008969:Molecular Sequence Data; D010802:Phylogeny; D016459:Prosthesis-Related Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S