title: Identification of the novel synthetic cannabimimetic 8-quinolinyl 4-methyl-3-(1-piperidinylsulfonyl)benzoate (QMPSB) and other designer drugs in herbal incense.
abstract: The identification and structural elucidation of the novel synthetic cannabimimetic 8-quinolinyl 4-methyl-3-(1-piperidinylsulfonyl)benzoate (QMPSB) by GC-MS, LC-MS and NMR is reported. QMPSB was identified in Queensland, Australia on plant material packaged as herbal incense. The identification of QMPSB was initially hampered due to trans-esterification occurring in the extraction solvent. An investigation of the trans-esterification of QMPSB in methanol and ethanol was conducted and analytical data for the respective methyl and ethyl esters are reported. Analytical data is presented for two other compounds detected on seized plant material packaged as herbal incense: the synthetic cannabimimetic 1-[(N-methylpiperidin-2-yl)methyl]-3-(4-methyl-1-naphthoyl)indole (MAM-1220) and the JWH-081 analogue 1-(cyclohexylmethyl)-3-(4-methoxy-1-naphthoyl)indole (CHM-081).
authors.affiliation: Forensic Chemistry, Queensland Health Forensic and Scientific Services, Brisbane, Australia. Electronic address: Karen.blakey@health.qld.gov.au.
authors.forename: Karen
authors.initials: K
authors.lastname: Blakey
authors.affiliation: Magnetic Resonance Facility, School of Natural Sciences, Griffith University, Brisbane, Australia.
authors.forename: Sue
authors.initials: S
authors.lastname: Boyd
authors.affiliation: Forensic Chemistry, Queensland Health Forensic and Scientific Services, Brisbane, Australia.
authors.forename: Sarah
authors.initials: S
authors.lastname: Atkinson
authors.affiliation: Forensic Chemistry, Queensland Health Forensic and Scientific Services, Brisbane, Australia; Magnetic Resonance Facility, School of Natural Sciences, Griffith University, Brisbane, Australia.
authors.forename: Jenna
authors.initials: J
authors.lastname: Wolf
authors.affiliation: Saxion University of Applied Sciences, the Netherlands.
authors.forename: Pim M
authors.initials: PM
authors.lastname: Slottje
authors.affiliation: Forensic Chemistry, Queensland Health Forensic and Scientific Services, Brisbane, Australia.
authors.forename: Katrina
authors.initials: K
authors.lastname: Goodchild
authors.affiliation: Forensic Chemistry, Queensland Health Forensic and Scientific Services, Brisbane, Australia.
authors.forename: Jenny
authors.initials: J
authors.lastname: McGowan
mesh_terms: D001565:Benzoates / Q000032:analysis*; D002186:Cannabinoids / Q000032:analysis*; D002853:Chromatography, Liquid; D015198:Designer Drugs / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012906:Smoke; D013449:Sulfonamides / Q000032:analysis*
chemical_list: C519013:8-quinolinyl 4-methyl-3-(1-piperidinylsulfonyl)benzoate; D001565:Benzoates; D002186:Cannabinoids; D015198:Designer Drugs; D012906:Smoke; D013449:Sulfonamides
keywords: 8-Quinolinyl 4-methyl-3-(1-piperidinylsulfonyl)benzoate (QMPSB); Arylsulfonamides; Herbal Incense; Methyl AM-1220; Synthetic cannabinoid