title: Mycotic aortic aneurysm due to intravesical BCG immunotherapy: Clinical manifestations and diagnostic challenges.
abstract: A live, attenuated form of Mycobacterium bovis, bacillus Calmette-Guérin (BCG), is commonly used as intravesical immunotherapy for non-invasive urothelial bladder carcinoma. While complications are rare, dissemination can occur. A case of mycotic aortic aneurysm following BCG administration with recovery of Mycobacterium bovis in culture is reported. A review of the published experience with this problem is also presented.
authors.affiliation: Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
authors.forename: Brittany J
authors.initials: BJ
authors.lastname: Holmes
authors.affiliation: Department of Medicine, Division of Infectious Diseases, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
authors.forename: Richard W
authors.initials: RW
authors.lastname: LaRue
authors.affiliation: Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
authors.forename: James H
authors.initials: JH
authors.lastname: Black
authors.affiliation: Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
authors.forename: Kim
authors.initials: K
authors.lastname: Dionne
authors.affiliation: Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
authors.forename: Nicole M
authors.initials: NM
authors.lastname: Parrish
authors.affiliation: Department of Medicine, Division of Infectious Diseases, The Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address: mmelia4@jhmi.edu.
authors.forename: Michael T
authors.initials: MT
authors.lastname: Melia
keywords: Aorta; Bacillus Calmette–Guérin (BCG); Mycobacterium bovis; Mycotic aneurysm; Psoas muscle abscess