title: Implementation of a pharmaceutical care programme for patients receiving new molecular-targeted agents in a clinical trial unit.
abstract: A pharmaceutical care programme was implemented at our hospital in early 2013. The main objectives were to analyse and describe the pharmaceutical interventions made, to calculate adherence, interventions and to evaluate patient satisfaction with the care programme. We performed a single-centre descriptive and prospective intervention in cancer patients who received oral chemotherapy as part of a clinical trial in 2013. Eighty-three patients were included. Median age was 58 years (range, 31-80) and 42 patients (50.6%) were men. We recorded 23 interventions, 13 of which were associated with drug interactions. The mean percentage of adherence was 98.9%. The interview with the pharmacist was considered to be very important by 84.6% of the respondents. A total of 92.3% said that they would like to speak to the pharmacist at subsequent visits. The doubts detected during the visits enable us to conclude that the information patients receive with respect to their study medication is usually incomplete. An integrated pharmaceutical care programme for cancer patients participating in clinical trials with oral cytostatic drugs was successful in terms of adherence and patient satisfaction and makes it possible to guarantee the safety and effectiveness of treatment on an individual basis.
authors.affiliation: Department of Pharmacy, Hospital Clinic Barcelona, Barcelona, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Riu
authors.affiliation: Department of Medical Oncology, Hospital Clinic Barcelona, Barcelona, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Gaba
authors.affiliation: Department of Medical Oncology, Hospital Clinic Barcelona, Barcelona, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Victoria
authors.affiliation: Department of Pharmacy, Hospital Clinic Barcelona, Barcelona, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Molas
authors.affiliation: Department of Pharmacy, Hospital Clinic Barcelona, Barcelona, Spain.
authors.forename: F
authors.initials: F
authors.lastname: do Pazo
authors.affiliation: Department of Pharmacy, Hospital Clinic Barcelona, Barcelona, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Gómez
authors.affiliation: Department of Pharmacy, Hospital Clinic Barcelona, Barcelona, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Creus
authors.affiliation: Department of Medical Oncology, Hospital Clinic Barcelona, Barcelona, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Vidal
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D003907:Dexamethasone / Q000008:administration & dosage / Q000009:adverse effects; D004347:Drug Interactions; D005260:Female; D006792:House Calls; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D058990:Molecular Targeted Therapy / Q000009:adverse effects / Q000379:methods*; D009369:Neoplasms / Q000188:drug therapy*; D017060:Patient Satisfaction; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects; D011446:Prospective Studies; D011795:Surveys and Questionnaires
chemical_list: D000970:Antineoplastic Agents; D003907:Dexamethasone; D011241:Prednisone
keywords: adherence; clinical trials; patient education; patient information; patient satisfaction