title: LINGUAL THYROID: 35-YEAR EXPERIENCE AT A TERTIARY CARE REFERRAL CENTER.
abstract: OBJECTIVE
  Lingual thyroid (LT) results from a developmental abnormality due to failure of the thyroid gland to descend to its pretracheal position. Given the low incidence of this disease, standardized management recommendations are lacking. We aimed to describe our institution's experience in LT management and to suggest a practice algorithm.
  
  
  METHODS
  We conducted a retrospective review of LT diagnosed at Mayo Clinic, Rochester, Minnesota, between 1976 and 2010. Demographics, clinical presentation, laboratory data, treatment received, and outcomes were collected.
  
  
  RESULTS
  We identified 29 patients with LT. Eighty-three percent were female; age at diagnosis ranged from 2 weeks to 68 years. Almost one-third of patients were symptomatic, with the most common symptoms being cough and hoarseness. The diagnosis of LT was incidental in 9 patients (31%). Seventy-two percent of patients developed hypothyroidism. Levothyroxine was the treatment of choice, followed by thyroidectomy. Two asymptomatic euthyroid patients were followed without any intervention.
  
  
  CONCLUSIONS
  Management of patients with LT should be individualized and guided by the patient's symptoms and thyroid hormone status.
authors.forename: Barbara G
authors.initials: BG
authors.lastname: Carranza Leon
authors.forename: Adina
authors.initials: A
authors.lastname: Turcu
authors.forename: Rebecca
authors.initials: R
authors.lastname: Bahn
authors.forename: Diana S
authors.initials: DS
authors.lastname: Dean
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D046151:Lingual Thyroid / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D063128:Tertiary Health Care / Q000706:statistics & numerical data; D055815:Young Adult