title: Iron Catalyzed Highly Enantioselective Epoxidation of Cyclic Aliphatic Enones with Aqueous H2O2.
abstract: An iron complex with a C1-symmetric tetradentate N-based ligand catalyzes the asymmetric epoxidation of cyclic enones and cyclohexene ketones with aqueous hydrogen peroxide, providing the corresponding epoxides in good to excellent yields and enantioselectivities (up to 99% yield, and 95% ee), under mild conditions and in short reaction times. Evidence is provided that reactions involve an electrophilic oxidant, and this element is employed in performing site selective epoxidation of enones containing two alkene sites.
authors.affiliation: QBIS Research Group, Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona , Campus Montilivi, Girona E-17071, Catalonia Spain.
authors.forename: Olaf
authors.initials: O
authors.lastname: Cussó
authors.affiliation: QBIS Research Group, Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona , Campus Montilivi, Girona E-17071, Catalonia Spain.
authors.forename: Marco
authors.initials: M
authors.lastname: Cianfanelli
authors.affiliation: QBIS Research Group, Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona , Campus Montilivi, Girona E-17071, Catalonia Spain.
authors.forename: Xavi
authors.initials: X
authors.lastname: Ribas
authors.affiliation: Organic Chemistry & Catalysis, Debye Institute for Nanomaterials Science, Utrecht University , Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.
authors.forename: Robertus J M
authors.initials: RJ
authors.lastname: Klein Gebbink
authors.affiliation: QBIS Research Group, Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona , Campus Montilivi, Girona E-17071, Catalonia Spain.
authors.forename: Miquel
authors.initials: M
authors.lastname: Costas