title: A Prospective, Comparative Study for the Evaluation of Postoperative Pain and Quality of Recovery in Patients Undergoing Robotic Versus Open Hysterectomy for Staging of Endometrial Cancer.
abstract: OBJECTIVE
  To measure and compare postoperative pain and patient satisfaction in patients undergoing either robotic or open laparotomy for surgical staging of endometrial cancer.
  
  
  METHODS
  Prospective, comparative study (Canadian Task Force classification II).
  
  
  METHODS
  University hospital.
  
  
  METHODS
  A total of 142 patients undergoing either robotic or open laparotomy for surgical staging of endometrial cancer.
  
  
  METHODS
  Patients scheduled for surgical staging of endometrial cancer at a single institution were identified. The patients underwent either robotic or open hysterectomy for staging of endometrial cancer. The choice of operative approach (robotic vs laparotomy) was made by the faculty physician before enrollment. Patients participated in the study for up to 48 hours for pain assessments and up to 10 ± 3 days postoperatively for quality of recovery assessments.
  
  
  RESULTS
  The following measurements were performed: postoperative pain with the visual analog scale (VAS), 24-hour opioid consumption, and quality of recovery using the Quality of Recovery Questionnaire (QoR-40). The study was terminated owing to futility, given the lack of open procedures at our institution. Despite that lack of statistically significant difference between VAS scores at rest and with leg extension, there was a significant decrease in 24-hour opioid consumption in the robotic group. In addition, the QoR-40 showed an increased perception of recovery in patients within the robotic group compared with the laparotomy group.
  
  
  CONCLUSIONS
  Patients with endometrial cancer who underwent robotic surgery had decreased postoperative opioid consumption and improved quality of recovery compared with those who underwent surgery via laparotomy.
authors.affiliation: Department of Gynecologic Oncology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: David E
authors.initials: DE
authors.lastname: Cohn
authors.affiliation: Department of Anesthesiology, The Ohio State Wexner Medical Center, Columbus, OH. Electronic address: Karina.CastellonLarios@osumc.edu.
authors.forename: Karina
authors.initials: K
authors.lastname: Castellon-Larios
authors.affiliation: Department of Gynecologic Oncology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: Laura
authors.initials: L
authors.lastname: Huffman
authors.affiliation: Department of Gynecologic Oncology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: Ritu
authors.initials: R
authors.lastname: Salani
authors.affiliation: Department of Gynecologic Oncology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Fowler
authors.affiliation: Department of Gynecologic Oncology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: Larry J
authors.initials: LJ
authors.lastname: Copeland
authors.affiliation: Department of Gynecologic Oncology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: David M
authors.initials: DM
authors.lastname: O'Malley
authors.affiliation: Department of Gynecologic Oncology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: Floor J
authors.initials: FJ
authors.lastname: Backes
authors.affiliation: Department of Gynecologic Oncology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: Eric L
authors.initials: EL
authors.lastname: Eisenhauer
authors.affiliation: Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Abdel-Rasoul
authors.affiliation: Department of Anesthesiology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: Erika G
authors.initials: EG
authors.lastname: Puente
authors.affiliation: Department of Anesthesiology, The Ohio State Wexner Medical Center, Columbus, OH.
authors.forename: Sergio D
authors.initials: SD
authors.lastname: Bergese
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage*; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D007813:Laparotomy / Q000379:methods; D008875:Middle Aged; D009367:Neoplasm Staging; D010149:Postoperative Pain / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery; D017060:Patient Satisfaction; D011183:Postoperative Complications; D011446:Prospective Studies; D065287:Robotic Surgical Procedures / Q000379:methods; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
chemical_list: D000701:Analgesics, Opioid
keywords: Endometrial cancer; Laparotomy; Postoperative pain; Quality of recovery; Robotic surgery