title: ST-elevation myocardial infarction in a young adult secondary to giant coronary aneurysm thrombosis: an important sequela of Kawasaki disease and a management challenge.
abstract: Thrombosis of a coronary artery aneurysm (CAA) is a rare trigger for ST-elevation myocardial infarction (STEMI) and an important cause of STEMI in young adults previously affected by Kawasaki disease. Initial management should proceed in line with standard STEMI-management guidelines advocating antiplatelet medication and emergency coronary angiography. Acute CAA thrombosis presents the interventional cardiologist with unique challenges during attempted percutaneous revascularisation. In the absence of consensus guidelines, experiential reporting can therefore be of great value. We report on a 36-year-old Vietnamese woman presenting with an inferior STEMI secondary to two giant thrombosed aneurysms of the right coronary artery. Coronary wiring and thrombus aspiration temporarily improved coronary flow but recurrent thrombus with distal embolisation resulted in ventricular fibrillation and cardiogenic shock. Emergency surgical revascularisation subsequently provided a definitive and successful outcome. We discuss the challenges of percutaneous coronary intervention in this scenario and review previous reports to give an overview of principles of decision-making and management.
authors.affiliation: Monash Heart, Monash Cardiovascular Research Centre & Monash University, Clayton, Victoria, Australia.
authors.forename: Elizabeth L
authors.initials: EL
authors.lastname: Potter
authors.affiliation: Monash Heart, Monash Cardiovascular Research Centre & Monash University, Clayton, Victoria, Australia.
authors.forename: Ian T
authors.initials: IT
authors.lastname: Meredith
authors.affiliation: Heart Health Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
authors.forename: Peter James
authors.initials: PJ
authors.lastname: Psaltis
mesh_terms: D000328:Adult; D002637:Chest Pain / Q000175:diagnosis / Q000503:physiopathology; D003323:Coronary Aneurysm / Q000150:complications* / Q000473:pathology / Q000601:surgery; D017023:Coronary Angiography / Q000379:methods; D003328:Coronary Thrombosis / Q000150:complications* / Q000473:pathology / Q000601:surgery; D004562:Electrocardiography / Q000379:methods; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology; D006801:Humans; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications* / Q000473:pathology; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D012770:Shock, Cardiogenic / Q000150:complications / Q000628:therapy; D016896:Treatment Outcome