title: Alkenes with antioxidative activities from Murraya koenigii (L.) Spreng.
abstract: Four new alkenes (1-4), and six known alkenes (5-12) were isolated from Murraya koenigii (L.) Spreng. Their structures were elucidated on the basis of spectroscopic analyses and references. Compounds (1-12) were evaluated for antioxidative activities. Among them, compounds 1, 2, 4, and 7 exhibited significant antioxidative activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay with IC50=21.4-49.5 μM. The known compounds (5-12) were isolated from this plant for the first time.
authors.affiliation: Department of Graduate Students, College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China. Electronic address: maqinge2006@163.com.
authors.forename: Qin-Ge
authors.initials: QG
authors.lastname: Ma
authors.affiliation: Department of Graduate Students, College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Xu
authors.affiliation: Department of Graduate Students, College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China.
authors.forename: Zhi-Pei
authors.initials: ZP
authors.lastname: Sang
authors.affiliation: Department of Pharmacology, College of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Rong-Rui
authors.initials: RR
authors.lastname: Wei
authors.affiliation: Department of Graduate Students, College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China.
authors.forename: Wen-Min
authors.initials: WM
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Ya-Lun
authors.initials: YL
authors.lastname: Su
authors.affiliation: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Jian-Bo
authors.initials: JB
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Ai-Guo
authors.initials: AG
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Teng-Fei
authors.initials: TF
authors.lastname: Ji
authors.affiliation: Department of Graduate Students, College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China.
authors.forename: Lu-Jun
authors.initials: LJ
authors.lastname: Li
mesh_terms: D000475:Alkenes / Q000737:chemistry* / Q000302:isolation & purification; D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification; D002942:Circular Dichroism; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D032101:Murraya / Q000737:chemistry* / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry / Q000378:metabolism
chemical_list: D000475:Alkenes; D000975:Antioxidants; D010936:Plant Extracts
keywords: Alkene; Antioxidative activity; Murraya koenigii