title: Literature Review of Cognitive Neuroscience and Anorexia Nervosa.
abstract: Studies published between the beginning of 2013 and May 2015 on the neuropsychological functioning of patients with anorexia nervosa compared with healthy participants framed in the context of the Research Domain Criteria matrix identifies evidence for functional differences in three domains: Negative Valance Systems-negative attentional biases and lack of neural responsivity to hunger; Cognitive Systems-limited congruence between clinical and cognitive performance, poorer non-verbal than verbal performance, altered attentional styles to disorder related stimuli, perceptual processing impairment in discriminating body images, weaknesses in central coherence, set shifting weaknesses at low weight status, decision-making weaknesses, and greater neural resources required for working memory; Systems for Social Processes-patients appear to have a different attentional response to faces, and perception and understanding of self and others. Hence, there is evidence to suggest that patients with anorexia nervosa have a specific neuropsychological performance style across tasks in three domains of functioning. Some current controversies and areas for future development are identified.
authors.affiliation: Feeding and Eating Disorders Service, Department of Child and Adolescent Mental Health, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, WC1N 3JH, UK. marie-claire.reville@nhs.net.|College of Life and Environmental Sciences, University of Exeter, Exeter, UK. marie-claire.reville@nhs.net.
authors.forename: Marie-Claire
authors.initials: MC
authors.lastname: Reville
authors.affiliation: College of Life and Environmental Sciences, University of Exeter, Exeter, UK.|Department of Psychology, University of Bath, Bath, UK.
authors.forename: Lorna
authors.initials: L
authors.lastname: O'Connor
authors.affiliation: Feeding and Eating Disorders Service, Department of Child and Adolescent Mental Health, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, WC1N 3JH, UK.|College of Life and Environmental Sciences, University of Exeter, Exeter, UK.
authors.forename: Ian
authors.initials: I
authors.lastname: Frampton
mesh_terms: D000856:Anorexia Nervosa / Q000503:physiopathology / Q000523:psychology*; D001288:Attention; D000066494:Cognitive Neuroscience; D003657:Decision Making; D006801:Humans; D008570:Memory, Short-Term; D009483:Neuropsychological Tests
keywords: Anorexia nervosa; Cognitive; Neuropsychology; Review