title: [Value of urine sediment analyzer in the screening of urinary tract infection in cancer patients].
abstract: OBJECTIVE
  To evaluate the value of urine sediment analyzer in the screening of clinically suspected urinary tract infection (UTI) in cancer patients.
  
  
  METHODS
  The results of bacterial count of 1 053 midstream urine samples by UF-1000i urine sediment analyzer (UF-1000i urine sediment analyzer, UF-1000i) were compared with the results of bacterial culture. Moreover, the results of distinguishing bacterial species by the bacterial scattergram were compared with the results of bacteria culture. At the same time, the sensitivity, specificity, positive predictive value and negative predictive value of UF-1000i analyzer for UTI screening were evaluated.
  
  
  RESULTS
  Of all the 1 053 samples, the top three bacteria were E. coli, Enterococci and P. aeruginosa. The top three malignant tumors of UTI were bladder, lung cancer and cervical cancers. The positive rate of UF-1000i analyzer was 20% (211/1 053), and that of bacteria culture was 17.9% (188/1 053). There was statistically no significant difference in the positive rates between the two methods (χ(2)=1.636, P>0.05), and the two methods had a considerable consistency (Kappa=0.756). Compared with the clinical diagnosis, UTI screening by UF-1000i analyzer showed a sensitivity of 79.6% (160/201), specificity of 95.5% (814/852), positive predictive value of 80.8% (160/198) and negative predictive value of 95.2%(814/855). The distribution of cocci and bacilli acquired by the bacterial scattergram was basically in accordance with the results of bacterial culture.
  
  
  CONCLUSIONS
  Bacterial count by UF-1000i analyzer plays an important role in early screening of UTI, and the bacterial scattergram may help to distinguish bacterial species, providing reference for the use of antibiotics in early medication.
authors.affiliation: Clinical Laboratory, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
authors.forename: Cuiling
authors.initials: C
authors.lastname: Zheng
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Han
authors.forename: Shana
authors.initials: S
authors.lastname: Feng
authors.forename: Jingzhi
authors.initials: J
authors.lastname: Wang
authors.forename: Mengqian
authors.initials: M
authors.lastname: Yin
authors.forename: Yan
authors.initials: Y
authors.lastname: Cheng
authors.forename: Jun
authors.initials: J
authors.lastname: Qi
mesh_terms: D058491:Bacterial Load; D016983:Enterococcus / Q000302:isolation & purification; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007958:Leukocyte Count; D008175:Lung Neoplasms / Q000652:urine*; D011237:Predictive Value of Tests; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D012680:Sensitivity and Specificity; D001749:Urinary Bladder Neoplasms / Q000652:urine*; D014552:Urinary Tract Infections / Q000175:diagnosis* / Q000382:microbiology / Q000652:urine; D002583:Uterine Cervical Neoplasms / Q000652:urine*