title: A Systematic Review on Immediate Loading of Implants Used to Support Overdentures Opposed by Conventional Prostheses: Factors That Might Influence Clinical Outcomes.
abstract: OBJECTIVE
  Different treatment protocols in terms of number, diameter, and suprastructure design have been proposed for immediately loaded implants that are used to support mandibular overdentures opposed by maxillary conventional dentures. The aim of this study was to investigate the influence of these protocols on survival rates as well as clinical and prosthodontic outcomes.
  
  
  METHODS
  Several electronic databases were searched for all relevant articles published from 1966 to June 2014. Only randomized controlled trials and prospective studies with a minimum follow-up of 12 months were selected. The primary outcomes of interest were the success and survival rates of the implants. Prosthodontic complications were also evaluated.
  
  
  RESULTS
  Fourteen studies fulfilled the inclusion criteria. Of the studies identified, nine were randomized controlled trials and five were prospective studies. The mean follow-up period was 3 years or less for the vast majority of the studies. The reported survival and success rates were comparable to that of conventional loading for most of the included studies. No specific immediate loading protocol seemed to perform better in terms of clinical and prosthodontic outcomes.
  
  
  CONCLUSIONS
  Immediate loading protocols of mandibular overdentures seem to be a viable alternative to conventional loading. It was not possible to recommend a specific treatment protocol related to the number, diameter of the implants, and attachment system used. Long-term, well-designed studies comparing different immediate loading modalities could help to establish a protocol that delivers the most clinically predictable, efficient, and cost-effective outcome for edentulous patients in need of implant overdentures.
authors.forename: Kostas
authors.initials: K
authors.lastname: Zygogiannis
authors.forename: Daniel
authors.initials: D
authors.lastname: Wismeijer
authors.forename: Irene Ha
authors.initials: IH
authors.lastname: Aartman
authors.forename: Reham B
authors.initials: RB
authors.lastname: Osman
mesh_terms: D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported; D003781:Denture Retention; D003824:Denture, Complete; D003828:Denture, Overlay; D006801:Humans; D057893:Immediate Dental Implant Loading; D009066:Mouth, Edentulous / Q000534:rehabilitation; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants