title: Microvascular invasion in hepatocellular carcinoma.
abstract: Microvascular invasion is a crucial histopathologic prognostic factor for hepatocellular carcinoma. We reviewed the literature and aimed to draw attention to clinicopathologic and imaging findings that may predict the presence of microvascular invasion in hepatocellular carcinoma. Imaging findings suggesting microvascular invasion are disruption of capsule, irregular tumor margin, peritumoral enhancement, multifocal tumor, increased tumor size, and increased glucose metabolism on positron emission tomography-computed tomography. In the presence of typical findings, microvascular invasion may be predicted.
authors.affiliation: Department of Radiology, Hacettepe University School of Medicine Ankara, Turkey; Department of Radiology, Zonguldak Atatürk State Hospital, Zonguldak, Turkey. musturayk@yahoo.com.
authors.forename: Emre
authors.initials: E
authors.lastname: Ünal
authors.forename: İlkay Sedakat
authors.initials: İS
authors.lastname: İdilman
authors.forename: Deniz
authors.initials: D
authors.lastname: Akata
authors.forename: Mustafa Nasuh
authors.initials: MN
authors.lastname: Özmen
authors.forename: Muşturay
authors.initials: M
authors.lastname: Karçaaltıncaba
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008113:Liver Neoplasms / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D012189:Retrospective Studies
chemical_list: D005947:Glucose