title: A Profilometry-Based Dentifrice Abrasion Method for V8 Brushing Machines Part II: Comparison of RDA-PE and Radiotracer RDA Measures.
abstract: OBJECTIVE
  The purpose of this study was to compare the abrasivity of commercial dentifrices by two techniques: the conventional gold standard radiotracer-based Radioactive Dentin Abrasivity (RDA) method; and a newly validated technique based on V8 brushing that included a profilometry-based evaluation of dentin wear. This profilometry-based method is referred to as RDA-Profilometry Equivalent, or RDA-PE.
  
  
  METHODS
  A total of 36 dentifrices were sourced from four global dentifrice markets (Asia Pacific [including China], Europe, Latin America, and North America) and tested blindly using both the standard radiotracer (RDA) method and the new profilometry method (RDA-PE), taking care to follow specific details related to specimen preparation and treatment.
  
  
  RESULTS
  Commercial dentifrices tested exhibited a wide range of abrasivity, with virtually all falling well under the industry accepted upper limit of 250; that is, 2.5 times the level of abrasion measured using an ISO 11609 abrasivity reference calcium pyrophosphate as the reference control. RDA and RDA-PE comparisons were linear across the entire range of abrasivity (r2 = 0.7102) and both measures exhibited similar reproducibility with replicate assessments. RDA-PE assessments were not just linearly correlated, but were also proportional to conventional RDA measures.
  
  
  CONCLUSIONS
  The linearity and proportionality of the results of the current study support that both methods (RDA or RDA-PE) provide similar results and justify a rationale for making the upper abrasivity limit of 250 apply to both RDA and RDA-PE.
authors.forename: Eva
authors.initials: E
authors.lastname: Schneiderman
authors.forename: Ellen
authors.initials: E
authors.lastname: Colón
authors.forename: Donald J
authors.initials: DJ
authors.lastname: White
authors.forename: Samuel
authors.initials: S
authors.lastname: St John
mesh_terms: D002131:Calcium Pyrophosphate / Q000009:adverse effects; D003802:Dentifrices / Q000009:adverse effects*; D003804:Dentin / Q000473:pathology; D006244:Hardness; D006801:Humans; D011849:Radioactive Tracers; D012015:Reference Standards; D015203:Reproducibility of Results; D014072:Tooth Abrasion / Q000145:classification / Q000209:etiology*; D014092:Tooth Root / Q000473:pathology; D014099:Toothbrushing / Q000295:instrumentation* / Q000379:methods
chemical_list: D003802:Dentifrices; D011849:Radioactive Tracers; D002131:Calcium Pyrophosphate