title: Synthesis of Some Novel 2-Amino-5-arylazothiazole Disperse Dyes for Dyeing Polyester Fabrics and Their Antimicrobial Activity.
abstract: The present work describes the synthesis of a series of four novel biologically active 2-amino-5-arylazothiazole disperse dyes containing the sulfa drug nucleus. The structures of the synthesized thiazole derivatives are confirmed using UV-spectrophotometry, infrared and nuclear magnetic resonance techniques and elemental analysis. The synthesized dyes are applied to polyester fabrics as disperse dyes and their fastness properties to washing, perspiration, rubbing, sublimation, and light are evaluated. The synthesized compounds exhibit promising biological efficiency against selected Gram-positive and Gram-negative pathogenic bacteria as well as fungi.
authors.affiliation: Textile Research Division, National Research Center, Dokki, Giza, P. O. Box.12611, Egypt. hatem197@yahoo.com.
authors.forename: Hatem E
authors.initials: HE
authors.lastname: Gaffer
authors.affiliation: Textile Research Division, National Research Center, Dokki, Giza, P. O. Box.12611, Egypt. m_gaballa@yahoo.com.|Chemistry Department, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia. m_gaballa@yahoo.com.
authors.forename: Moustafa M G
authors.initials: MM
authors.lastname: Fouda
authors.affiliation: Chemistry Department, Faculty of Science, Taif University, P. O. Box 888, Taif 21974, Saudi Arabia. mohamedezzat200@hotmail.com.|Department of Chemical Engineering, Higher Institute for Engineering and Technology, New Damietta, P. O. Box 34518, Egypt. mohamedezzat200@hotmail.com.
authors.forename: Mohamed E
authors.initials: ME
authors.lastname: Khalifa
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001391:Azo Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D004396:Coloring Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D011091:Polyesters / Q000737:chemistry*; D013784:Textiles
chemical_list: D000890:Anti-Infective Agents; D001391:Azo Compounds; D004396:Coloring Agents; D011091:Polyesters
keywords: 2-aminothiazole; antimicrobial activity; azo dyes; dyeing; polyester; sulfaguanidine