title: Iron(II)-catalyzed asymmetric intramolecular olefin aminochlorination using chloride ion.
abstract: An iron-catalyzed enantioselective and diastereoselective intramolecular olefin aminochlorination reaction is reported (ee up to 92%, dr up to 15 : 1). In this reaction, a functionalized hydroxylamine and chloride ion are utilized as nitrogen and chlorine sources, respectively. This new method tolerates a range of synthetically valuable internal olefins that are all incompatible with existing asymmetric olefin aminochlorination methods.
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, Georgia, 30303, USA.
authors.forename: Cheng-Liang
authors.initials: CL
authors.lastname: Zhu
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, Georgia, 30303, USA.
authors.forename: Jun-Shan
authors.initials: JS
authors.lastname: Tian
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, Georgia, 30303, USA.|Department of Chemistry, Beijing Normal University, Beijing, 100875, China.
authors.forename: Zhen-Yuan
authors.initials: ZY
authors.lastname: Gu
authors.affiliation: Department of Chemistry, Beijing Normal University, Beijing, 100875, China.
authors.forename: Guo-Wen
authors.initials: GW
authors.lastname: Xing
authors.affiliation: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, Georgia, 30303, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Xu