title: Evaluating the transmission routes of hand, foot, and mouth disease in Guangdong, China.
abstract: Although it is an enteroviral infectious disease, recent studies suggest that respiratory transmission might play a role in the transmission of hand, foot, and mouth disease (HFMD). We evaluated the transmission modes (respiratory and fecal-oral transmission) of HFMD among children using a case-control study in Guangdong, China. Our analyses suggested that fecal-oral transmission might be the principal transmission mode of HFMD among children in the study area, and handwashing habits of the children and their parents should be emphasized to control this infection.
authors.affiliation: Guangdong Provincial Centre for Disease Control and Prevention, Guangzhou, China.
authors.forename: Limei
authors.initials: L
authors.lastname: Sun
authors.affiliation: Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
authors.forename: Hualiang
authors.initials: H
authors.lastname: Lin
authors.affiliation: Guangdong Provincial Centre for Disease Control and Prevention, Guangzhou, China.
authors.forename: Jinyan
authors.initials: J
authors.lastname: Lin
authors.affiliation: Guangdong Provincial Centre for Disease Control and Prevention, Guangzhou, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: He
authors.affiliation: Guangdong Provincial Centre for Disease Control and Prevention, Guangzhou, China.
authors.forename: Aiping
authors.initials: A
authors.lastname: Deng
authors.affiliation: Guangdong Provincial Centre for Disease Control and Prevention, Guangzhou, China.
authors.forename: Min
authors.initials: M
authors.lastname: Kang
authors.affiliation: Guangdong Provincial Centre for Disease Control and Prevention, Guangzhou, China.
authors.forename: Hanri
authors.initials: H
authors.lastname: Zeng
authors.affiliation: Guangdong Provincial Centre for Disease Control and Prevention, Guangzhou, China.
authors.forename: Wenjun
authors.initials: W
authors.lastname: Ma
authors.affiliation: Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China. Electronic address: zyh@cdcp.org.cn.
authors.forename: Yonghui
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D016022:Case-Control Studies; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004770:Enterovirus / Q000502:physiology*; D005243:Feces / Q000821:virology; D005260:Female; D006235:Hand Disinfection; D006232:Hand, Foot and Mouth Disease / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D006801:Humans; D007223:Infant; D017053:Infection Control; D008297:Male; D009055:Mouth / Q000821:virology
keywords: Case-control study; China; Hand, foot, and mouth disease; Handwashing; Transmission