title: Routine cerebrospinal fluid analysis during 'de novo' ventriculoperitoneal shunt insertion: Single Institution Experience.
abstract: Background Cerebrospinal fluid (CSF) sampling is performed during ventriculoperitoneal (VP) shunting procedure surgery for early detection of infection. We have performed a retrospective study to determine whether routine intraoperative CSF sampling at new VP shunt insertion has predicted shunt infection or changed subsequent surveillance or management. Method From January 2011 to December 2013, 99 patients underwent first time VP shunt insertion at our hospital. The data collected from Beaumont Hospital Information System and operating theatre logbook. The reviewed data were patient demographics, the clinical condition requiring VP shunt procedure, shunt type, date of VP shunt insertion, date of VP shunt infection or malfunction and laboratory data. Results A first time VP shunt insertion procedure was performed in 99 patients. During the VP shunt insertion procedure, 64 patients had CSF sampling for microbiological analysis. The CSF culture was negative in all samples. All patients were followed up for 12 months. During the follow-up period, a total of 15 patients underwent VP shunt revision. Three of the shunt revisions were secondary to infection. The three infected shunt cases had sterile CSF cultures at the time of insertion. Conclusion There appears to be no correlation between CSF sampling during first time VP shunt insertion and the later development VP shunt infection. This questions the need for routine CSF sampling at the time of insertion. This would be confirmed as a part of future randomised trials.
authors.affiliation: a Department of Neurosurgery , Beaumont Hospital , Dublin , Ireland.
authors.forename: Ayman
authors.initials: A
authors.lastname: Khalil
authors.affiliation: a Department of Neurosurgery , Beaumont Hospital , Dublin , Ireland.
authors.forename: Tafadzwa
authors.initials: T
authors.lastname: Mandiwanza
authors.affiliation: a Department of Neurosurgery , Beaumont Hospital , Dublin , Ireland.
authors.forename: Zaitun
authors.initials: Z
authors.lastname: Zakaria
authors.affiliation: a Department of Neurosurgery , Beaumont Hospital , Dublin , Ireland.
authors.forename: Darach
authors.initials: D
authors.lastname: Crimmins
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002555:Cerebrospinal Fluid / Q000737:chemistry*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D013997:Time Factors; D017287:Ventriculoperitoneal Shunt / Q000379:methods; D055815:Young Adult
keywords: Cerebrospinal fluid; cerebrospinal fluid shunt; hydrocephalus