title: Spindle Cell Carcinoma of the Larynx: A Confusing Diagnosis for the Pathologist and Clinician.
abstract: Laryngeal spindle cell carcinoma (SpCC) is an uncommon subtype of squamous cell carcinoma which represents 0.5% of all laryngeal squamous cell carcinomas. It is a biphasic tumor consisting of the combination of a malignant mesenchymal spindle cell component and a squamous cell component that includes dysplasia, carcinoma in situ, or invasive carcinoma. Although it has aggressive biological features, the probability of making a diagnosis in the early stages is high as it often leads to obstructive symptoms in the early period. Due to its low incidence, there is no clear consensus on prognostic factors and optimal treatment strategies yet. In this paper, a 60-year-old laryngeal SpCC case that was effectively treated with wide local excision followed by adjuvant radiotherapy was presented with the literature.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Akdeniz University School of Medicine, 07059 Antalya, Turkey.
authors.forename: Asli
authors.initials: A
authors.lastname: Bostanci
authors.affiliation: Department of Pathology, Akdeniz University School of Medicine, 07059 Antalya, Turkey.
authors.forename: Gulay
authors.initials: G
authors.lastname: Ozbilim
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Akdeniz University School of Medicine, 07059 Antalya, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Turhan