title: Sense of coherence as a mediator between hostility and health-related quality of life among coronary heart disease patients.
abstract: OBJECTIVE
  To explore the association between hostility and health-related quality of life (HRQoL) among coronary heart disease (CHD) patients, and whether these associations are mediated by sense of coherence (SOC).
  
  
  BACKGROUND
  Intervention research has shown that a decrease in levels of hostility leads to an increase of HRQoL among individuals with CHD. However, the mechanisms that link hostility and HRQoL in CHD patients are not clear.
  
  
  METHODS
  509 CHD patients (mean age 58.8 ± 7.3, 29.3% female) were examined.
  
  
  RESULTS
  Hostility was associated with poorer mental HRQoL. Adding SOC to the model weakened the strength of the association between hostility and mental HRQoL. The effect of hostility on mental HRQoL was explained for 61.9% by SOC. Neither hostility nor SOC was associated with physical HRQoL.
  
  
  CONCLUSIONS
  Our findings indicate that low SOC may partially explain the adverse effect of hostility on low mental HRQoL in CHD patients.
authors.affiliation: Graduate School Kosice Institute for Society and Health, Faculty of Medicine, Safarik University, Tr. SNP 1, 040 11 Kosice, Slovak Republic. Electronic address: silarova.barbora@gmail.com.
authors.forename: Barbora
authors.initials: B
authors.lastname: Silarova
authors.affiliation: Graduate School Kosice Institute for Society and Health, Faculty of Medicine, Safarik University, Tr. SNP 1, 040 11 Kosice, Slovak Republic; Department of Social and Behavioural Medicine, Faculty of Medicine, Safarik University, Tr. SNP 1, 040 11 Kosice, Slovak Republic.
authors.forename: Iveta
authors.initials: I
authors.lastname: Nagyova
authors.affiliation: Graduate School Kosice Institute for Society and Health, Faculty of Medicine, Safarik University, Tr. SNP 1, 040 11 Kosice, Slovak Republic.
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Rosenberger
authors.affiliation: Graduate School Kosice Institute for Society and Health, Faculty of Medicine, Safarik University, Tr. SNP 1, 040 11 Kosice, Slovak Republic; Department of Community and Occupational Medicine, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
authors.forename: Jitse P
authors.initials: JP
authors.lastname: van Dijk
authors.affiliation: Department of Community and Occupational Medicine, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
authors.forename: Sijmen A
authors.initials: SA
authors.lastname: Reijneveld
mesh_terms: D000328:Adult; D000368:Aged; D003324:Coronary Artery Disease / Q000523:psychology*; D005260:Female; D006791:Hostility; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D060685:Sense of Coherence
keywords: Coronary heart disease; Health-related quality of life; Hostility; Mediation analysis; Sense of coherence