title: Applications of cyclodextrins in medical textiles - review.
abstract: This paper presents data on the general properties and complexing ability of cyclodextrins and assessment methods (phase solubility, DSC tests and X-ray diffraction, FTIR spectra, analytical method). It focuses on the formation of drug deposits on the surface of a textile underlayer, using a cyclodextrin compound favoring the inclusion of a drug/active principle and its release onto the dermis of patients suffering from skin disorders, or for protection against insects. Moreover, it presents the kinetics, duration, diffusion flow and release media of the cyclodextrin drug for in vitro studies, as well as the release modeling of the active principle. The information focuses on therapies: antibacterial, anti-allergic, antifungal, chronic venous insufficiency, psoriasis and protection against insects. The pharmacodynamic agents/active ingredients used on cotton, woolen and synthetic textile fabrics are presented.
authors.affiliation: "Gh. Asachi" Technical University Iasi, Department: Textiles, Leather and Industrial Management, 29 Mangeron Street, Iasi 20050, Romania. Electronic address: rcezar2010@yahoo.com.
authors.forename: Cezar-Doru
authors.initials: CD
authors.lastname: Radu
authors.affiliation: "Gh. Asachi" Technical University Iasi, Department: Textiles, Leather and Industrial Management, 29 Mangeron Street, Iasi 20050, Romania. Electronic address: oanaparteni@yahoo.com.
authors.forename: Oana
authors.initials: O
authors.lastname: Parteni
authors.affiliation: "Gr.T. Popa" University of Medicine and Pharmacy, Faculty of Pharmacy/Department of Pharmaceutical Technology, 11 Universitatii Street, Iasi, Romania. Electronic address: ochiuzd@yahoo.com.
authors.forename: Lacramioara
authors.initials: L
authors.lastname: Ochiuz
mesh_terms: D000818:Animals; D003505:Cyclodextrins / Q000737:chemistry*; D004339:Drug Compounding; D016503:Drug Delivery Systems; D006801:Humans; D012871:Skin Diseases / Q000188:drug therapy; D013784:Textiles
chemical_list: D003505:Cyclodextrins
keywords: Acryloyl chloride (PubChem CID: 13140); Ag (PubChem CID: 23954); Beta-Cyclodextrin (PubChem CID: 71306822); Cyclodextrin; Drug release; Epichlorohydrin (PubChem CID: 7835); Itaconic acid (PubChem CID: 811); Methyl-Beta-cyclodextrin (PubChem CID: 51051622); Permethrin (PubChem CID: 40326); Polyhexamethylene biguanide (PubChem CID: 20977); Skin disorders; Textile fabric; Triclosan (PubChem CID: 5564)