title: Systematic review and meta-analysis of single-port versus conventional laparoscopic hysterectomy.
abstract: BACKGROUND
  The choice between single-port laparoscopic hysterectomy (SPLH) and conventional laparoscopic hysterectomy (CLH) remains unclear.
  
  
  OBJECTIVE
  To evaluate the feasibility, safety, and comparative effectiveness of SPLH and CLH.
  
  
  METHODS
  PubMed, Web of Science, and the Cochrane Library were searched in February 2015 using combinations of the terms "single port," "single incision," "single site," "laparoscopic hysterectomy," and "laparoendoscopic hysterectomy."
  
  
  METHODS
  Randomized controlled trials (RCTs) and retrospective studies comparing SPLH and CLH were included if they reported at least one quantitative outcome.
  
  
  METHODS
  Study characteristics, quality, and outcomes were assessed. The primary outcomes were procedure failure and perioperative complications. Odds ratio (ORs) and 95% confidence intervals (CIs) were calculated.
  
  
  RESULTS
  Eighteen studies (6 RCTs, 12 retrospective studies) were included. As compared with CLH, SPLH had a higher failure rate (OR 6.37, 95% CI 3.34-12.14; P<0.001). The frequency of perioperative complications did not differ (OR 0.89, 95% CI 0.45-1.74; P=0.73).
  
  
  CONCLUSIONS
  There is no significant difference in the frequency of perioperative complications between SPLH and CLH. However, the higher rate of procedure failure in SPLH should be taken into consideration.
authors.affiliation: First School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
authors.forename: Lilin
authors.initials: L
authors.lastname: Yang
authors.affiliation: Department of Gynecology, First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Gao
authors.affiliation: Department of Gynecology, First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zeng
authors.affiliation: Department of Reproductive Medicine, First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Weng
authors.affiliation: First School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China. Electronic address: gynspluo@hotmail.com.
authors.forename: Songping
authors.initials: S
authors.lastname: Luo
mesh_terms: D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D010535:Laparoscopy / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology*; D016032:Randomized Controlled Trials as Topic; D017211:Treatment Failure
keywords: Conventional laparoscopic hysterectomy; Meta-analysis; Single-port laparoscopic hysterectomy