title: [Toxic shock syndrome].
abstract: The authors present an up-to-date review of toxic shock syndrome (TSS) - a life-threatening condition where toxins of the Gram-positive bacteria Staphyloccocus aureus and Streptococcus pyogenes play a key role in the pathogenesis. The authors provide insight into the epidemiology and pathogenesis of the disease and point out the relevant patient history data and clinical signs and symptoms that may indicate progression of TSS. Last but not least, the state of the art diagnostic and therapeutic approaches to early and full blown TSS are summarized. Case reports are presented to illustrate two different etiological forms of this relatively rare nosological entity.
authors.forename: T
authors.initials: T
authors.lastname: Tyll
authors.forename: M
authors.initials: M
authors.lastname: Bílková
authors.forename: A
authors.initials: A
authors.lastname: Revinová
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.forename: M
authors.initials: M
authors.lastname: Čurdová
authors.forename: M
authors.initials: M
authors.lastname: Zlámal
authors.forename: M
authors.initials: M
authors.lastname: Holub
mesh_terms: D000818:Animals; D001427:Bacterial Toxins / Q000378:metabolism / Q000633:toxicity*; D006801:Humans; D012772:Shock, Septic / Q000188:drug therapy / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000378:metabolism; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000378:metabolism
chemical_list: D001427:Bacterial Toxins
keywords: toxic shock syndrome - toxigenic strain - toxin - superantigen.