title: Ruxolitinib Induces Interleukin 17 and Ameliorates Chronic Mucocutaneous Candidiasis Caused by STAT1 Gain-of-Function Mutation.
authors.affiliation: Department of Dermatology, Venereology and Allergology.
authors.forename: Rotraut
authors.initials: R
authors.lastname: Mössner
authors.affiliation: Department of Dermatology, Venereology and Allergology.
authors.forename: Nina
authors.initials: N
authors.lastname: Diering
authors.affiliation: Institute of Medical Microbiology.
authors.forename: Oliver
authors.initials: O
authors.lastname: Bader
authors.affiliation: Department of Dermatology, Venereology and Allergology.
authors.forename: Susann
authors.initials: S
authors.lastname: Forkel
authors.affiliation: Department of Hematology and Oncology, University Medical Center Göttingen.
authors.forename: Tobias
authors.initials: T
authors.lastname: Overbeck
authors.affiliation: Institute of Medical Microbiology.
authors.forename: Uwe
authors.initials: U
authors.lastname: Gross
authors.affiliation: Center for Chronic Immunodeficiency, University Medical Center Freiburg, Germany Institute of Immunity and Transplantation, University College London, United Kingdom.
authors.forename: Bodo
authors.initials: B
authors.lastname: Grimbacher
authors.affiliation: Department of Dermatology, Venereology and Allergology.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Schön
authors.affiliation: Department of Dermatology, Venereology and Allergology.
authors.forename: Timo
authors.initials: T
authors.lastname: Buhl
mesh_terms: D002178:Candidiasis, Chronic Mucocutaneous / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D006801:Humans; D020381:Interleukin-17 / Q000097:blood / Q000235:genetics* / Q000378:metabolism; D008297:Male; D009154:Mutation; D009570:Nitriles; D011720:Pyrazoles / Q000627:therapeutic use*; D011743:Pyrimidines; D050794:STAT1 Transcription Factor / Q000097:blood / Q000235:genetics* / Q000378:metabolism; D014059:Tongue / Q000473:pathology
chemical_list: D020381:Interleukin-17; D009570:Nitriles; D011720:Pyrazoles; D011743:Pyrimidines; D050794:STAT1 Transcription Factor; C494079:STAT1 protein, human; C540383:ruxolitinib