title: Optical coherence tomography to evaluate the effects of oxidative hair dye on the fiber.
abstract: OBJECTIVE
  Oxidative hair dyes can damage the hair, since these chemical procedures are involved to change the fiber structure and therefore changes in their mechanical and surface properties. Evaluate and compare the effect of the two colors of oxidative hair dye emulsions on Caucasian hair. This research analyzed the Dark brown hair untreated (I); Dark brown hair treated with light brown dye (II); Dark brown hair treated with light blond dye (III); Light blond hair untreated (IV); Light blond hair treated with light brown dye (V); Light blond hair treated with light blond dye (VI) on Caucasian hair.
  
  
  METHODS
  The hair samples were submitted to breaking strength, color, and optical coherence tomography (OCT) analysis.
  
  
  RESULTS
  For the breaking strength assay no presented statistically significant differences between treatments. The parameters of color and brightness can differ in some hair dye formulations, but also the hair type can respond differently. The OCT images of the sample I and IV was possible observed, clearly Medulla and Cortex, which was not observed clearly after treatment with both oxidative hair dye colors.
  
  
  CONCLUSIONS
  Based on the results, the oxidative hair dyes increased alteration in color and ultrastructure of hair.
authors.affiliation: Laboratory of Cosmetology, Pharmaceutical Sciences School, University of São Paulo, São Paulo, Brazil.
authors.forename: Maria Valéria Robles
authors.initials: MV
authors.lastname: Velasco
authors.affiliation: Laboratory of Cosmetology, Pharmaceutical Sciences School, University of São Paulo, São Paulo, Brazil.
authors.forename: Simone Rachid Pfannemüller
authors.initials: SR
authors.lastname: de Abreu
authors.affiliation: Lasers and Applications Center, Nuclear and Energy Research Institute, IPEN-CNEN/SP, São Paulo, Brazil.
authors.forename: Anderson Zanardi
authors.initials: AZ
authors.lastname: de Freitas
authors.affiliation: Healthy Skin Foundation and Hair and Skin Research and Treatment Institute, São Paulo, Brazil.
authors.forename: Valcinir
authors.initials: V
authors.lastname: Bedin
authors.affiliation: Laboratory of Cosmetology, Pharmaceutical Sciences School, University of São Paulo, São Paulo, Brazil.
authors.forename: André Rolim
authors.initials: AR
authors.lastname: Baby
authors.affiliation: Laboratory of Cosmetology, Pharmaceutical Sciences School, University of São Paulo, São Paulo, Brazil. robson.gama@fmabc.br.|Pharmacy Research Laboratory, Pharmacy School, Faculty of Medicine ABC, Santo André, Brazil. robson.gama@fmabc.br.|Semi-industrial Pharmacy School Lab, Pharmacy School, University of Santo Amaro, São Paulo, Brazil. robson.gama@fmabc.br.
authors.forename: Robson Miranda
authors.initials: RM
authors.lastname: da Gama
mesh_terms: D006197:Hair / Q000166:cytology* / Q000187:drug effects* / Q000502:physiology; D006200:Hair Color / Q000187:drug effects* / Q000502:physiology; D006202:Hair Dyes; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D066298:In Vitro Techniques; D016877:Oxidants / Q000008:administration & dosage; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013718:Tensile Strength / Q000187:drug effects* / Q000502:physiology; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D006202:Hair Dyes; D016877:Oxidants
keywords: breaking strength; color; hair dye; optical coherence tomography