title: On a Fitzhugh-Nagumo type model for the pulse-like jasmonate defense response in plants.
abstract: A mechanistic model of the Fitzhugh-Nagumo type is proposed for the pulse-like jasmonate response in plants. The model is composed of a bistable signaling pathway coupled to a negative feedback loop. The bistable signaling pathway describes a recently discovered positive feedback loop involving jasmonate and the MYC2 transcription factor regulating promoter activity during plant defense. The negative feedback loop is assumed to reflect a second jasmonate-dependent signaling pathway that is also used for ethylene signaling. The impact of the negative feedback loop is to destroy the high-level jasmonate fixed-point of the bistable jasmonate/MYC2 module. As a result, the high-level state becomes a ghost attractor and the jasmonate defense response becomes pulse-like.
authors.affiliation: Department of Physics, Kasetsart University, Bangkok 10900, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Chiangga
authors.affiliation: Department of Physics, Kasetsart University, Bangkok 10900, Thailand.
authors.forename: W
authors.initials: W
authors.lastname: Pornkaveerat
authors.affiliation: Center for the Ecological Study of Perception and Action, University of Connecticut, 406 Babbidge Road, Storrs, CT 06269, USA; Department of Physics, University of Connecticut, 2152 Hillside Road, Storrs, CT 06269, USA. Electronic address: till.frank@uconn.edu.
authors.forename: T D
authors.initials: TD
authors.lastname: Frank
mesh_terms: D003517:Cyclopentanes / Q000378:metabolism*; D025461:Feedback, Physiological; D017343:Genes, Plant; D055641:Mathematical Concepts; D008954:Models, Biological; D054883:Oxylipins / Q000378:metabolism*; D010937:Plant Growth Regulators / Q000378:metabolism; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D015398:Signal Transduction
chemical_list: D003517:Cyclopentanes; D054883:Oxylipins; D010937:Plant Growth Regulators; D010940:Plant Proteins; C011006:jasmonic acid
keywords: Excitable media; Fitzhugh–Nagumo model; Jasmonate; Plant defense; Pulse response