title: Introducing Contactless Blood Pressure Assessment Using a High Speed Video Camera.
abstract: Recent studies demonstrated that blood pressure (BP) can be estimated using pulse transit time (PTT). For PTT calculation, photoplethysmogram (PPG) is usually used to detect a time lag in pulse wave propagation which is correlated with BP. Until now, PTT and PPG were registered using a set of body-worn sensors. In this study a new methodology is introduced allowing contactless registration of PTT and PPG using high speed camera resulting in corresponding image-based PTT (iPTT) and image-based PPG (iPPG) generation. The iPTT value can be potentially utilized for blood pressure estimation however extent of correlation between iPTT and BP is unknown. The goal of this preliminary feasibility study was to introduce the methodology for contactless generation of iPPG and iPTT and to make initial estimation of the extent of correlation between iPTT and BP "in vivo." A short cycling exercise was used to generate BP changes in healthy adult volunteers in three consecutive visits. BP was measured by a verified BP monitor simultaneously with iPTT registration at three exercise points: rest, exercise peak, and recovery. iPPG was simultaneously registered at two body locations during the exercise using high speed camera at 420 frames per second. iPTT was calculated as a time lag between pulse waves obtained as two iPPG's registered from simultaneous recoding of head and palm areas. The average inter-person correlation between PTT and iPTT was 0.85 ± 0.08. The range of inter-person correlations between PTT and iPTT was from 0.70 to 0.95 (p < 0.05). The average inter-person coefficient of correlation between SBP and iPTT was -0.80 ± 0.12. The range of correlations between systolic BP and iPTT was from 0.632 to 0.960 with p < 0.05 for most of the participants. Preliminary data indicated that a high speed camera can be potentially utilized for unobtrusive contactless monitoring of abrupt blood pressure changes in a variety of settings. The initial prototype system was able to successfully generate approximation of pulse transit time and showed high intra-individual correlation between iPTT and BP. Further investigation of the proposed approach is warranted.
authors.affiliation: Chronic Disease Informatics Program, Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, 2024 East Monument St., Baltimore, 21205, MD, USA. ijeong1@jhmi.edu.
authors.forename: In Cheol
authors.initials: IC
authors.lastname: Jeong
authors.affiliation: Chronic Disease Informatics Program, Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, 2024 East Monument St., Baltimore, 21205, MD, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Finkelstein
mesh_terms: D000328:Adult; D001795:Blood Pressure Determination / Q000295:instrumentation* / Q000379:methods*; D005080:Exercise Test; D005240:Feasibility Studies; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D017156:Photoplethysmography; D063177:Pulse Wave Analysis / Q000295:instrumentation / Q000379:methods; D012867:Skin; D014743:Videotape Recording / Q000295:instrumentation*
keywords: Blood pressure; Non-contact monitoring; Pulse transit time; Video