title: Mood Differences Among Parkinson's Disease Patients With Mild Cognitive Impairment.
abstract: Studies with healthy elderly adults suggest that apathy, depression, and anxiety are more common among individuals with mild cognitive impairment (MCI). This study examined differences in mood/amotivational symptoms among patients with Parkinson's disease (PD) with and without MCI. Patients with PD (N=214) underwent neurocognitive evaluations including assessment of apathy (Apathy Scale), depression (Beck Depression Inventory-II), and trait anxiety (State-Trait Anxiety Inventory trait scale). Trait anxiety and depression were more severe in patients with PD with MCI. Delineation of MCI into amnestic and nonamnestic subtypes revealed greater depression, apathy, and anxiety among patients with PD with amnestic MCI relative to cognitively intact patients with PD. Patients with PD and MCI report greater mood symptoms compared to patients with PD who are cognitively intact.
authors.affiliation: From the Depts. of Clinical and Health Psychology (JDJ, PM, JL, DB) and Neurology (MSO, DB), Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville.
authors.forename: Jacob D
authors.initials: JD
authors.lastname: Jones
authors.affiliation: From the Depts. of Clinical and Health Psychology (JDJ, PM, JL, DB) and Neurology (MSO, DB), Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville.
authors.forename: Paul
authors.initials: P
authors.lastname: Mangal
authors.affiliation: From the Depts. of Clinical and Health Psychology (JDJ, PM, JL, DB) and Neurology (MSO, DB), Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville.
authors.forename: Jacob
authors.initials: J
authors.lastname: Lafo
authors.affiliation: From the Depts. of Clinical and Health Psychology (JDJ, PM, JL, DB) and Neurology (MSO, DB), Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Okun
authors.affiliation: From the Depts. of Clinical and Health Psychology (JDJ, PM, JL, DB) and Neurology (MSO, DB), Center for Movement Disorders and Neurorestoration, McKnight Brain Institute, University of Florida, Gainesville.
authors.forename: Dawn
authors.initials: D
authors.lastname: Bowers
mesh_terms: D000368:Aged; D060825:Cognitive Dysfunction / Q000150:complications* / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000175:diagnosis / Q000209:etiology*; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D012044:Regression Analysis; D011795:Surveys and Questionnaires