title: [Need for resuscitation in preterm neonates less than 32 weeks treated with antenatal magnesium sulphate for neuroprotection].
abstract: BACKGROUND
  Magnesium sulphate administration is recommended for foetal neuroprotection in pregnant women at imminent risk of early preterm birth.
  
  
  OBJECTIVE
  To evaluate the relationship between intrapartum magnesium sulphate for foetal neuroprotection and delivery room resuscitation of preterm infants less 32 weeks.
  
  
  METHODS
  A prospective observational study was conducted on preterm infants less 32 weeks exposed to magnesium sulphate for neuroprotection, and a comparison made with another historic group immediately before starting this treatment. Cases in both groups that had not reached lung maturity with corticosteroids were rejected. The rates of resuscitation, morbidity and mortality for each of the groups were analysed and compared.
  
  
  RESULTS
  There was a total of 107 preterm, with 56 exposed to magnesium sulphate. Rate of advanced resuscitation were similar between the two groups. There were no other differences in mortality, invasive mechanical ventilation, time to first stool, and other comorbidities.
  
  
  CONCLUSIONS
  Intrapartum magnesium sulphate for foetal neuroprotection was not associated with an increased need for intensive delivery room resuscitation and other morbidities in these cohorts of less than 32 weeks preterm infants.
authors.affiliation: Unidad de Cuidados Intensivos Neonatales, Servicio de Pediatría, Hospital General Universitario Santa Lucía, Cartagena, Murcia, España. Electronic address: jmlloreda@gmail.com.
authors.forename: Jose María
authors.initials: JM
authors.lastname: Lloreda-Garcia
authors.affiliation: Unidad de Cuidados Intensivos Neonatales, Servicio de Pediatría, Hospital General Universitario Santa Lucía, Cartagena, Murcia, España.
authors.forename: Ana
authors.initials: A
authors.lastname: Lorente-Nicolás
authors.affiliation: Unidad de Cuidados Intensivos Neonatales, Servicio de Pediatría, Hospital General Universitario Santa Lucía, Cartagena, Murcia, España.
authors.forename: Francisca
authors.initials: F
authors.lastname: Bermejo-Costa
authors.affiliation: Unidad de Medicina Fetal, Servicio de Ginecología y Obstetricia, Hospital Universitario Santa Lucía, Complejo Hospitalario Universitario de Cartagena, Murcia, España.
authors.forename: Juan
authors.initials: J
authors.lastname: Martínez-Uriarte
authors.affiliation: Unidad de Medicina Fetal, Servicio de Ginecología y Obstetricia, Hospital Universitario Santa Lucía, Complejo Hospitalario Universitario de Cartagena, Murcia, España.
authors.forename: Rocío
authors.initials: R
authors.lastname: López-Pérez
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008278:Magnesium Sulfate / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D018696:Neuroprotective Agents / Q000008:administration & dosage* / Q000009:adverse effects; D011247:Pregnancy; D011295:Prenatal Care / Q000379:methods*; D011446:Prospective Studies; D012151:Resuscitation / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D018696:Neuroprotective Agents; D008278:Magnesium Sulfate
keywords: Delivery room resuscitation; Magnesio; Magnesium; Neuroprotección; Neuroprotection; Prematuros; Preterm; Reanimación neonatal