title: Antiphospholipid Syndrome and Libman-Sacks Endocarditis in a Bioprosthetic Mitral Valve.
abstract: This report describes one the first cases of antiphospholipid syndrome and Libman-Sacks endocarditis in a bioprosthetic valve. A redo mitral valve replacement was carried out owing to early deterioration of the prior valve. Initially it was considered secondary to rheumatic heart disease; however, pathology analysis and autoimmune workup revealed antiphospholipid syndrome with Libman-Sacks endocarditis. We believe certain populations with mitral valve stenosis may have an underlying antiphospholipid syndrome. As a result, there needs to be a lower threshold for identifying this disease.
authors.affiliation: Graduate Medical Education, Internal Medicine Residency Program, Oak Hill Hospital, Brooksville, Florida.
authors.forename: Eric H
authors.initials: EH
authors.lastname: Sladek
authors.affiliation: Cardiovascular Institute, Florida Hospital, Orlando, Florida. Electronic address: kaccola@cvsorlando.com.
authors.forename: Kevin D
authors.initials: KD
authors.lastname: Accola
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D001705:Bioprosthesis; D004696:Endocarditis / Q000150:complications* / Q000601:surgery; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000601:surgery*; D011183:Postoperative Complications / Q000601:surgery; D012086:Reoperation