title: One-step ligand exchange and switching from hydrophobic to water-stable hydrophilic superparamagnetic iron oxide nanoparticles by mechanochemical milling.
abstract: We describe a simple, rapid methodology for the synthesis of water-stable iron oxide nanoparticles (IONPs) compatible with a variety of aqueous buffers, based on mechanochemical milling exchange of covalently bound surface ligands on pre-fabricated oleic acid-protected IONPs. Application of milling for IONP ligand exchange eliminates steps required for transforming hydrophobic into negatively charged, water-soluble superparamagnetic IONPs.
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. W., H3A 0B8 Montreal, Canada. amy.blum@mcgill.ca tomislav.friscic@mcgill.ca.
authors.forename: Katalin V
authors.initials: KV
authors.lastname: Korpany
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. W., H3A 0B8 Montreal, Canada. amy.blum@mcgill.ca tomislav.friscic@mcgill.ca.
authors.forename: Cristina
authors.initials: C
authors.lastname: Mottillo
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. W., H3A 0B8 Montreal, Canada. amy.blum@mcgill.ca tomislav.friscic@mcgill.ca.
authors.forename: Jill
authors.initials: J
authors.lastname: Bachelder
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. W., H3A 0B8 Montreal, Canada. amy.blum@mcgill.ca tomislav.friscic@mcgill.ca.
authors.forename: Shoronia N
authors.initials: SN
authors.lastname: Cross
authors.affiliation: Department of Chemistry, Centre for Advanced Solar Materials, and Institute for Quantum Science and Technology, University of Calgary, 2500 University Drive N.W., Calgary, ABT2N 1N4, Canada.
authors.forename: Pengcheng
authors.initials: P
authors.lastname: Dong
authors.affiliation: Department of Chemistry, Centre for Advanced Solar Materials, and Institute for Quantum Science and Technology, University of Calgary, 2500 University Drive N.W., Calgary, ABT2N 1N4, Canada.
authors.forename: Simon
authors.initials: S
authors.lastname: Trudel
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. W., H3A 0B8 Montreal, Canada. amy.blum@mcgill.ca tomislav.friscic@mcgill.ca.
authors.forename: Tomislav
authors.initials: T
authors.lastname: Friščić
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. W., H3A 0B8 Montreal, Canada. amy.blum@mcgill.ca tomislav.friscic@mcgill.ca.
authors.forename: Amy Szuchmacher
authors.initials: AS
authors.lastname: Blum