title: [3 + 3]-Cycloaddition of Donor-Acceptor Cyclopropanes with Nitrile Imines Generated in Situ: Access to Tetrahydropyridazines.
abstract: Donor-acceptor cyclopropanes are reacted under the influence of a Lewis acid with hydrazonyl chlorides to afford tetrahydropyridazines. Formally, this transformation can be regarded as a [3 + 3]-cycloaddition of three-membered rings and nitrile imines generated in situ. This efficient method provides fast access to a variety of structurally diverse pyridazine derivatives. The structure of a typical product was confirmed by X-ray crystallography.
authors.affiliation: Institut für Organische Chemie, Technische Universität Braunschweig , Hagenring 30, 38106 Braunschweig, Germany.
authors.forename: Lennart K B
authors.initials: LK
authors.lastname: Garve
authors.affiliation: Institut für Organische Chemie, Technische Universität Braunschweig , Hagenring 30, 38106 Braunschweig, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Petzold
authors.affiliation: Institut für Organische Chemie, Technische Universität Braunschweig , Hagenring 30, 38106 Braunschweig, Germany.
authors.forename: Peter G
authors.initials: PG
authors.lastname: Jones
authors.affiliation: Institut für Organische Chemie, Technische Universität Braunschweig , Hagenring 30, 38106 Braunschweig, Germany.
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Werz