title: Integration of C/N-nutrient and multiple environmental signals into the ABA signaling cascade.
abstract: Due to their immobility, plants have developed sophisticated mechanisms to robustly monitor and appropriately respond to dynamic changes in nutrient availability. Carbon (C) and nitrogen (N) are especially important in regulating plant metabolism and development, thereby affecting crop productivity. In addition to their independent utilization, the ratio of C to N metabolites in the cell, referred to as the "C/N balance", is important for the regulation of plant growth, although molecular mechanisms mediating C/N signaling remain unclear. Recently ABI1, a protein phosphatase type 2C (PP2C), was shown to be a regulator of C/N response in Arabidopsis plants. ABI1 functions as a negative regulator of abscisic acid (ABA) signal transduction. ABA is versatile phytohormone that regulates multiple aspects of plant growth and adaptation to environmental stress. This review highlights the regulation of the C/N response mediated by a non-canonical ABA signaling pathway that is independent of ABA biosynthesis, as well as recent findings on the direct crosstalk between multiple cellular signals and the ABA signaling cascade.
authors.affiliation: a Faculty of Science and Graduate School of Life Science ; Hokkaido University ; Kita-ku Sapporo , Japan.
authors.forename: Yu
authors.initials: Y
authors.lastname: Lu
authors.affiliation: a Faculty of Science and Graduate School of Life Science ; Hokkaido University ; Kita-ku Sapporo , Japan.
authors.forename: Junji
authors.initials: J
authors.lastname: Yamaguchi
authors.affiliation: a Faculty of Science and Graduate School of Life Science ; Hokkaido University ; Kita-ku Sapporo , Japan.
authors.forename: Takeo
authors.initials: T
authors.lastname: Sato
mesh_terms: D000040:Abscisic Acid / Q000378:metabolism*; D002244:Carbon / Q000378:metabolism*; D004777:Environment; D009584:Nitrogen / Q000378:metabolism*; D010940:Plant Proteins / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D010940:Plant Proteins; D000040:Abscisic Acid; D002244:Carbon; D009584:Nitrogen
keywords: ABI1; SnRK; abscisic acid (ABA); carbon; nitrogen; nutrient availability; protein phosphorylation