title: Assessment of bloodstream infections and risk factors in an intensive care unit.
abstract: OBJECTIVE
  Nosocomial bloodstream infection (BSI) increases mortality rates, duration of stay in hospital, and treatment costs. This study was conducted to determine the rate and the risk factors of BSIs among intensive care unit patients.
  
  
  METHODS
  Sixty-four patients with BSIs (patient group) and 79 patients without a nosocomial infection (control group) were enrolled in the study. Centers for Disease Control and Prevention criteria were used for diagnosing BSIs. Potential risk factors were evaluated by multivariate logistic regression model.
  
  
  RESULTS
  The BSI development rate was 15.7% (64/407), with an incidence rate of 18.2/1000 patient days. Distribution of pathogens among BSI patients were as follows: gram-positive cocci, 42.18% (27/64); gram-negative cocci, 34.3% (22/64); and Candida spp., 23.4% (15/64). Risk factors were determined as intubation, arterial catheter, tracheostomy, duration of intubation, duration of catheter use, duration of nasogastric catheter, underlying diseases of chronic renal failure and diabetes mellitus, implemented treatments of sedation and enteral nutrition, and APACHE II score.
  
  
  CONCLUSIONS
  : BSIs are the leading cause of mortality and morbidity in intensive care unit patients. Determination of the local risk factors is important and necessary for decreasing the rate of BSIs and the mortality rates.
authors.forename: Aynur
authors.initials: A
authors.lastname: Süner
authors.forename: Ilkay
authors.initials: I
authors.lastname: Karaoğlan
authors.forename: Ayşe Ozlem
authors.initials: AO
authors.lastname: Mete
authors.forename: Mustafa
authors.initials: M
authors.lastname: Namiduru
authors.forename: Vuslat
authors.initials: V
authors.lastname: Boşnak
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Baydar
mesh_terms: D018806:APACHE; D016470:Bacteremia / Q000453:epidemiology*; D016022:Case-Control Studies; D055499:Catheter-Related Infections / Q000453:epidemiology; D016292:Procedural Sedation / Q000009:adverse effects; D003428:Cross Infection / Q000453:epidemiology*; D003920:Diabetes Mellitus / Q000453:epidemiology; D004750:Enteral Nutrition / Q000009:adverse effects; D005260:Female; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units; D007441:Intubation, Gastrointestinal / Q000009:adverse effects; D007442:Intubation, Intratracheal / Q000009:adverse effects; D007676:Kidney Failure, Chronic / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013997:Time Factors; D014139:Tracheostomy / Q000009:adverse effects; D014421:Turkey / Q000453:epidemiology