title: Cross-resistance patterns to ACCase-inhibitors in American sloughgrass (Beckmannia syzigachne Steud.) homozygous for specific ACCase mutations.
abstract: American sloughgrass is a troublesome annual grass weed in winter wheat field rotated with rice in China. The overreliance on acetyl-coenzyme A carboxylase (ACCase) inhibiting herbicides has resulted in resistance evolution in this weed. In this study, the cross-resistance patterns to fenoxaprop-p-ethyl, clodinafop-propargyl, fluazifop-p-butyl, haloxyfop-p-methyl, sethoxydim, clethodim and pinoxaden were established using purified plants individually homozygous for specific mutant ACCase alleles. Results indicated that 1781Leu allele endows high-level resistance to APPs, CHDs and pinoxaden while confers moderate resistance to haloxyfop-p-methyl. The 2027Cys and 2041Asn alleles endow high-level resistance to APPs and pinoxaden and lower level resistance to CHDs. The 2078Gly allele confers high-level resistance to all herbicides tested in this study, however, moderate resistance to sethoxydim. The 2096Ala very likely endows high-level resistance to fluazifop-p-butyl, haloxyfop-p-methyl and moderate resistance to sethoxydim. In addition, one undefined resistance mechanism was involved in population SD-04.
authors.affiliation: Key Laboratory of Pesticide Toxicology and Application Technique, College of Plant Protection, Shandong Agricultural University, Shandong Tai'an 271018, PR China.
authors.forename: Long
authors.initials: L
authors.lastname: Du
authors.affiliation: Key Laboratory of Pesticide Toxicology and Application Technique, College of Plant Protection, Shandong Agricultural University, Shandong Tai'an 271018, PR China.
authors.forename: Weitang
authors.initials: W
authors.lastname: Liu
authors.affiliation: Key Laboratory of Pesticide Toxicology and Application Technique, College of Plant Protection, Shandong Agricultural University, Shandong Tai'an 271018, PR China.
authors.forename: Guohui
authors.initials: G
authors.lastname: Yuan
authors.affiliation: Key Laboratory of Pesticide Toxicology and Application Technique, College of Plant Protection, Shandong Agricultural University, Shandong Tai'an 271018, PR China.
authors.forename: Wenlei
authors.initials: W
authors.lastname: Guo
authors.affiliation: Key Laboratory of Pesticide Toxicology and Application Technique, College of Plant Protection, Shandong Agricultural University, Shandong Tai'an 271018, PR China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Li
authors.affiliation: Key Laboratory of Pesticide Toxicology and Application Technique, College of Plant Protection, Shandong Agricultural University, Shandong Tai'an 271018, PR China. Electronic address: wangjx@sdau.edu.cn.
authors.forename: Jinxin
authors.initials: J
authors.lastname: Wang
mesh_terms: D000103:Acetyl-CoA Carboxylase / Q000037:antagonists & inhibitors / Q000235:genetics*; D003512:Cyclohexanones / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D053209:Herbicide Resistance / Q000235:genetics; D006540:Herbicides / Q000633:toxicity*; D006574:Heterocyclic Compounds, 2-Ring / Q000633:toxicity; D010080:Oxazoles / Q000633:toxicity; D010940:Plant Proteins / Q000037:antagonists & inhibitors / Q000235:genetics*; D006109:Poaceae / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D011422:Propionates / Q000633:toxicity; D011725:Pyridines / Q000633:toxicity
chemical_list: D003512:Cyclohexanones; D006540:Herbicides; D006574:Heterocyclic Compounds, 2-Ring; D010080:Oxazoles; D010940:Plant Proteins; D011422:Propionates; D011725:Pyridines; C441919:clethodim; C049437:sethoxydim; C050585:fluazifop-butyl; C054176:haloxyfop; C416661:fenoxaprop ethyl; D000103:Acetyl-CoA Carboxylase; C561036:clodinafop-propargyl; C542519:pinoxaden
keywords: ACCase gene; Beckmannia syzigachne; Cross-resistance; Homozygote; Mutation