title: Predicting VO2peak from Submaximal- and Peak Exercise Models: The HUNT 3 Fitness Study, Norway.
abstract: OBJECTIVE
  Peak oxygen uptake (VO2peak) is seldom assessed in health care settings although being inversely linked to cardiovascular risk and all-cause mortality. The aim of this study was to develop VO2peak prediction models for men and women based on directly measured VO2peak from a large healthy population.
  
  
  METHODS
  VO2peak prediction models based on submaximal- and peak performance treadmill work were derived from multiple regression analysis. 4637 healthy men and women aged 20-90 years were included. Data splitting was used to generate validation and cross-validation samples.
  
  
  RESULTS
  The accuracy for the peak performance models were 10.5% (SEE = 4.63 mL⋅kg(-1)⋅min(-1)) and 11.5% (SEE = 4.11 mL⋅kg(-1)⋅min(-1)) for men and women, respectively, with 75% and 72% of the variance explained. For the submaximal performance models accuracy were 14.1% (SEE = 6.24 mL⋅kg(-1)⋅min(-1)) and 14.4% (SEE = 5.17 mL⋅kg(-1)⋅min(-1)) for men and women, respectively, with 55% and 56% of the variance explained. The validation and cross-validation samples displayed SEE and variance explained in agreement with the total sample. Cross-classification between measured and predicted VO2peak accurately classified 91% of the participants within the correct or nearest quintile of measured VO2peak.
  
  
  CONCLUSIONS
  Judicious use of the exercise prediction models presented in this study offers valuable information in providing a fairly accurate assessment of VO2peak, which may be beneficial for risk stratification in health care settings.
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.|Valnesfjord Rehabilitation Center, Valnesfjord, Norway.
authors.forename: Henrik
authors.initials: H
authors.lastname: Loe
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Bjarne M
authors.initials: BM
authors.lastname: Nes
authors.affiliation: K.G. Jebsen Center of Exercise in Medicine at Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Ulrik
authors.initials: U
authors.lastname: Wisløff
mesh_terms: D000328:Adult; D001835:Body Weight; D005080:Exercise Test; D005260:Female; D006339:Heart Rate; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D009664:Norway; D010101:Oxygen Consumption / Q000502:physiology*; D015203:Reproducibility of Results