title: [Long-Term Outcome of Radiofrequency Ablation Therapy for Breast Cancer].
abstract: Although radiofrequency ablation (RFA) is promising for the local treatment of breast cancer, data concerning the longterm results are limited. The present study attempted to evaluate the safety and efficacy of RFA and to clarify patient outcomes after treatment. The study included 26 breast cancer patients treated with RFA between 2006 and 2010. There were no acute complications such as burns. All subjects were followed-up after breast radiation and systemic therapies. At the median follow-up period of 88 months, no local recurrence or distant metastases had occurred. After treatment, a hard lump was formed around the ablated area, which gradually decreased in size in all cases (p<0.001). The lumps were calcified in 9 cases. Nipple retraction persisted in 2 cases. However, it is necessary to recognize that a cosmetic result of RFA was not excellent in all cases, RFA appears to be a safe local treatment technique for breast cancer patients.
authors.affiliation: Dept. of General Surgery, Graduate School of Medicine, Chiba University.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nagashima
authors.forename: Masahiro
authors.initials: M
authors.lastname: Sakakibara
authors.forename: Takafumi
authors.initials: T
authors.lastname: Sangai
authors.forename: Junta
authors.initials: J
authors.lastname: Sakakibara
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Iwase
authors.forename: Shoko
authors.initials: S
authors.lastname: Hayama
authors.forename: Emi
authors.initials: E
authors.lastname: Ishigami
authors.forename: Takahito
authors.initials: T
authors.lastname: Masuda
authors.forename: Ayako
authors.initials: A
authors.lastname: Nakagawa
authors.forename: Masaru
authors.initials: M
authors.lastname: Miyazaki
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D002114:Calcinosis; D017115:Catheter Ablation / Q000009:adverse effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D021701:Sentinel Lymph Node Biopsy; D013997:Time Factors; D016896:Treatment Outcome