title: Regorafenib-induced hand-foot skin reaction with striking epidermal dysmaturation - a new histopathological pattern associated with the use of multi-kinase inhibitors.
authors.affiliation: Kempf und Pfaltz Histologische Diagnostik, Seminarstrasse 1, CH-8042, Zürich, Switzerland.|Hospital de La Princesa, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Llamas-Velasco
authors.affiliation: Kempf und Pfaltz Histologische Diagnostik, Seminarstrasse 1, CH-8042, Zürich, Switzerland.
authors.forename: I
authors.initials: I
authors.lastname: Hegyi
authors.affiliation: Dermatology Practice, Berne, Switzerland.
authors.forename: U
authors.initials: U
authors.lastname: Hesterberg
authors.affiliation: Hospital de La Princesa, Madrid, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Daudén
authors.affiliation: Fundación Jiménez Díaz, Madrid, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Requena
authors.affiliation: Kempf und Pfaltz Histologische Diagnostik, Seminarstrasse 1, CH-8042, Zürich, Switzerland.
authors.forename: W
authors.initials: W
authors.lastname: Kempf
mesh_terms: D003875:Drug Eruptions / Q000209:etiology*; D004817:Epidermis / Q000187:drug effects*; D005533:Foot Dermatoses / Q000209:etiology*; D006229:Hand Dermatoses / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010671:Phenylurea Compounds / Q000009:adverse effects*; D047428:Protein Kinase Inhibitors / Q000009:adverse effects*; D011725:Pyridines / Q000009:adverse effects*
chemical_list: D010671:Phenylurea Compounds; D047428:Protein Kinase Inhibitors; D011725:Pyridines; C559147:regorafenib