title: The medico-legal observation of an aggressive urogenital fibromatosis with isolated development not related to any traumatic event.
abstract: Desmoid tumor is a fibroproliferative neoplasm with an intermediate malignancy and it can be localized in every bodily district: some locations are considered exceptional, like the urogenital localization. The Author point out a rare case of giant idiopathic scrotal fibromatosis that was found during an autopsy. A widower, that lived alone in poor hygienic conditions, was found dead in his house. The Judicial Authority ordered the autopsy, that was performed two days later at the Medico-Legal Section of Milan University. External examinations revealed only the considerable dimension of the scrotum (cm 24 × 41). The cause of death was fixed in a cardiac tamponade due to a natural heart laceration localized in correspondence of a transmural infarction. The toxicological exam resulted negative, while the histopathological and immunohistochemical analysis qualify the scrotal mass as a desmoids tumor. Due to the absence of predisposing conditions and of fibroproliferative infiltration in bladder and retroperitoneal space, the neoplasm was configured as an idiopathic desmoid tumor. The presented case gives the reason for the discussion concerning medico-legal aspects that are typical of rare neoplasms.
authors.affiliation: Sezione di Medicina Legale e delle Assicurazioni-Dipartimento di Scienze Biomediche per la Salute- Università degli Studi di Milano, Via Luigi Mangiagalli 37, 20133 Milano MI, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Muccino
authors.affiliation: Sezione di Medicina Legale e delle Assicurazioni-Dipartimento di Scienze Biomediche per la Salute- Università degli Studi di Milano, Via Luigi Mangiagalli 37, 20133 Milano MI, Italy.
authors.forename: Guendalina
authors.initials: G
authors.lastname: Gentile
authors.affiliation: Centro Nazionale delle Ricerche-Istituto di Ricerca Genetica e Biomedica (IRGB)- Istituto Clinico Humanitas, Via Manzoni 113, 20089 Rozzano MI, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Mantero
authors.affiliation: Azienda Ospedaliera Papa Giovanni XXIII-Piazza OMS 1, 24127 Bergamo.
authors.forename: Matteo
authors.initials: M
authors.lastname: Marchesi
authors.affiliation: Sezione di Medicina Legale e delle Assicurazioni-Dipartimento di Scienze Biomediche per la Salute- Università degli Studi di Milano, Via Luigi Mangiagalli 37, 20133 Milano MI, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Rancati
authors.affiliation: Sezione di Medicina Legale e delle Assicurazioni-Dipartimento di Scienze Biomediche per la Salute- Università degli Studi di Milano, Via Luigi Mangiagalli 37, 20133 Milano MI, Italy. Electronic address: riccardo.zoia@unimi.it.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Zoja
mesh_terms: D000368:Aged; D018222:Desmoid Tumors / Q000473:pathology*; D049429:Forensic Pathology; D005834:Genital Neoplasms, Male / Q000473:pathology*; D006801:Humans; D033162:Incidental Findings; D008297:Male; D009361:Neoplasm Invasiveness; D012187:Retroperitoneal Space / Q000473:pathology; D012611:Scrotum / Q000473:pathology*; D001743:Urinary Bladder / Q000473:pathology
keywords: Aggressive fibromatosis; Autopsy; Desmoid tumor; Forensic pathology