title: Evaluation of Agreement between HRT III and iVue OCT in Glaucoma and Ocular Hypertension Patients.
abstract: Purpose. To determine the agreement between Moorfields Regression Analysis (MRA), Glaucoma Probability Score (GPS) of Heidelberg retinal tomograph (HRT III), and peripapillary nerve fibers thickness by iVue Optical Coherence Tomography (OCT). Methods. 72 eyes with ocular hypertension or primary open angle glaucoma (POAG) were included in the study: 54 eyes had normal visual fields (VF) and 18 had VF damage. All subjects performed achromatic 30° VF by Octopus Program G1X dynamic strategy and were imaged with HRT III and iVue OCT. Sectorial and global MRA, GPS, and OCT parameters were used for the analysis. Kappa statistic was used to assess the agreement between methods. Results. A significant agreement between iVue OCT and GPS for the inferotemporal quadrant (κ: 0.555) was found in patients with abnormal VF. A good overall agreement between GPS and MRA was found in all the eyes tested (κ: 0.511). A good agreement between iVue OCT and MRA was shown in the superonasal (κ: 0.656) and nasal (κ: 0.627) quadrants followed by the superotemporal (κ: 0.602) and inferotemporal (κ: 0.586) sectors in all the studied eyes. Conclusion. The highest percentages of agreement were found per quadrant of the MRA and the iVue OCT confirming that in glaucoma damage starts from the temporal hemiretina.
authors.affiliation: Department of Ophthalmology II, Faculty of Medicine and Psychology, "Sapienza" University of Rome, Sant'Andrea Hospital, 00100 Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Perdicchi
authors.affiliation: Anatomical-Clinical Laboratory for the Diagnosis and Treatment of Glaucoma and Neuroophthalmology, Eye Clinic, DINOGMI, University of Genoa, Viale Benedetto XV 5, 16132 Genoa, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Iester
authors.affiliation: Department of Ophthalmology II, Faculty of Medicine and Psychology, "Sapienza" University of Rome, Sant'Andrea Hospital, 00100 Rome, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Iacovello
authors.affiliation: Department of Ophthalmology II, Faculty of Medicine and Psychology, "Sapienza" University of Rome, Sant'Andrea Hospital, 00100 Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cutini
authors.affiliation: Department of Ophthalmology II, Faculty of Medicine and Psychology, "Sapienza" University of Rome, Sant'Andrea Hospital, 00100 Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Balestrieri
authors.affiliation: Department of Ophthalmology II, Faculty of Medicine and Psychology, "Sapienza" University of Rome, Sant'Andrea Hospital, 00100 Rome, Italy.
authors.forename: M G
authors.initials: MG
authors.lastname: Mutolo
authors.affiliation: Department of Ophthalmology, Miguel Servet University Hospital, Aragon Health Research Institute, 50009 Zaragoza, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Ferreras
authors.affiliation: Department of Ophthalmology II, Faculty of Medicine and Psychology, "Sapienza" University of Rome, Sant'Andrea Hospital, 00100 Rome, Italy.
authors.forename: M T
authors.initials: MT
authors.lastname: Contestabile
authors.affiliation: Department of Ophthalmology II, Faculty of Medicine and Psychology, "Sapienza" University of Rome, Sant'Andrea Hospital, 00100 Rome, Italy.
authors.forename: S M
authors.initials: SM
authors.lastname: Recupero