title: A Case Series of Acquired Drug Resistance-Associated Mutations in Human Immunodeficiency Virus-Infected Children: An Emerging Public Health Concern in Rural Africa.
abstract: The acquisition of drug-resistance mutations among African children living with in human immunodeficiency virus on antiretroviral treatment has been scarcely reported. This threatens the overall success of antiretroviral programs and the clinical outcomes of children in care. We present a well characterized series of children from rural Tanzania with acquired drug-resistance mutations to contribute to the better understanding of this emerging public health concern.
authors.affiliation: Swiss Tropical and Public Health Institute, Basel; University of Basel; Ifakara Health Institute, United Republic of Tanzania.
authors.forename: Anna
authors.initials: A
authors.lastname: Gamell
authors.affiliation: Swiss Tropical and Public Health Institute, Basel; University of Basel.
authors.forename: Lukas
authors.initials: L
authors.lastname: Muri
authors.affiliation: Ifakara Health Institute , United Republic of Tanzania.
authors.forename: Alex
authors.initials: A
authors.lastname: Ntamatungiro
authors.affiliation: Ifakara Health Institute , United Republic of Tanzania.
authors.forename: Daniel
authors.initials: D
authors.lastname: Nyogea
authors.affiliation: Ifakara Health Institute , United Republic of Tanzania.
authors.forename: Lameck B
authors.initials: LB
authors.lastname: Luwanda
authors.affiliation: Swiss Tropical and Public Health Institute, Basel; University of Basel.
authors.forename: Christoph
authors.initials: C
authors.lastname: Hatz
authors.affiliation: University of Basel; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel.
authors.forename: Manuel
authors.initials: M
authors.lastname: Battegay
authors.affiliation: Swiss Tropical and Public Health Institute, Basel; University of Basel.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Felger
authors.affiliation: Swiss Tropical and Public Health Institute, Basel; University of Basel.
authors.forename: Marcel
authors.initials: M
authors.lastname: Tanner
authors.affiliation: Molecular Virology, Department Biomedicine-Petersplatz , University of Basel , Switzerland.
authors.forename: Thomas
authors.initials: T
authors.lastname: Klimkait
authors.affiliation: Swiss Tropical and Public Health Institute, Basel; University of Basel; Ifakara Health Institute, United Republic of Tanzania; ISGLOBAL, Barcelona Centre for International Health Research, Hospital Clínic-Universitat de Barcelona, Spain.
authors.forename: Emilio
authors.initials: E
authors.lastname: Letang
keywords: Africa; HIV; antiretroviral treatment; children; resistance mutations