title: [A Case of Pancreatic Head Cancer Showing Pathological Complete Response to Neoadjuvant Chemoradiation Therapy].
abstract: The patient was a 64-year-old woman. She was referred to our institute because of a chief complaint of upper abdominal pain. Abdominal computed tomographic scan revealed a 35 mm hypovascular tumor in the pancreatic head and superior mesenteric vein (SMV), as well as thrombosis. We chose neoadjuvant chemoradiation therapy (NACRT) (S-1/RT, 50.4 Gy/28 Fr) and anticoagulants. After the treatment, the primary lesion showed a partial response, and the SMV thrombosis was reduced. We performed pancreaticoduodenectomy. Histopathological examination revealed no cancer cells in the pancreas. Pathological evaluation revealed grade Ⅳ tumor according to the Evans classification. The patient had had no recurrence for 10 months after the pancreaticoduodenectomy.
authors.affiliation: Dept. of Surgery, Kurume University School of Medicine.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Nakama
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Kawahara
authors.forename: Yoriko
authors.initials: Y
authors.lastname: Nomura
authors.forename: Daisuke
authors.initials: D
authors.lastname: Muroya
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Arai
authors.forename: Hiroto
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Masafumi
authors.initials: M
authors.lastname: Yasunaga
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Horiuchi
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Akagi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tanaka
authors.forename: Makiko
authors.initials: M
authors.lastname: Yasumoto
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Okabe
authors.forename: Takuji
authors.initials: T
authors.lastname: Torimura
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Naito
authors.forename: Koji
authors.initials: K
authors.lastname: Okuda
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D059248:Chemoradiotherapy; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D010094:Oxonic Acid / Q000627:therapeutic use*; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000628:therapy*; D016577:Pancreaticoduodenectomy; D005641:Tegafur / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid