title: [Examination of the Cases Given Primary Tumor Resection after Systemic Therapy for Metastatic Breast Cancer].
abstract: We examined the records of patients with stage Ⅳ breast cancer who underwent primary tumor resection after systemic therapy. In our department, in 2013, there were 8 such cases. The average local tumor diameter was 59 mm. There was 1 case of metastases to the liver, 2 cases to the lung, 3 cases to the bone, and 1 case to the kidney. Three cases had lymph node metastases. Two cases were treated with hormonal therapy, and 6 cases received chemotherapy as preoperative systemic therapy. All cases underwent Bt plus Ax. Approximately 2 years after the surgery, 5 of the 8 patients were alive. The postoperative local control was good and we were able to continue systemic treatment for the distant metastases in all cases. We think that resection of the primary tumor improved the quality of life of the patients. However, for 1 fatal case, a brain metastasis was detected shortly after surgery. Therefore, we need to consider the patient's condition carefully before we operate.
authors.affiliation: Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Hara
authors.forename: Kenichi
authors.initials: K
authors.lastname: Sakurai
authors.forename: Keita
authors.initials: K
authors.lastname: Adachi
authors.forename: Asako
authors.initials: A
authors.lastname: Fujiwara
authors.forename: Youko
authors.initials: Y
authors.lastname: Ono
authors.forename: Saki
authors.initials: S
authors.lastname: Nagashima
authors.forename: Shuhei
authors.initials: S
authors.lastname: Suzuki
authors.forename: Eiko
authors.initials: E
authors.lastname: Waga
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Hirano
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Enomoto
authors.forename: Sadao
authors.initials: S
authors.lastname: Amano
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D064847:Multimodal Imaging; D009362:Neoplasm Metastasis; D011788:Quality of Life; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents