title: [A Case of Carcinosarcoma of the Esophagus Treated with Chemoradiotherapy].
abstract: Carcinosarcoma of the esophagus is a rare malignant neoplasm. We report a case of an 87-year-old man treated with chemoradiotherapy. The main presenting complaint was hiccups. Histological analysis of a biopsy from the tumor demonstrated a carcinosarcoma. The clinical diagnosis was T2N0M0, cStageⅡ. In consideration of his advanced age, a past history of cerebral infarction, high blood pressure, aortic valve sclerosis, and chronic renal failure (Cr 1.5-1.8 mg/dL), chemoradiotherapy consisting of TS-1 40 mg/day with radiotherapy of 66 Gy was administered to the patient. The carcinosarcoma decreased in size on endoscopic examination in response to the chemoradiotherapy. Surgery with extended lymphadenectomy for esophageal carcinosarcoma is the standard treatment, but chemotherapy may be a good choice for local control for patients who cannot undergo surgical resection.
authors.affiliation: Dept. of Surgery, Kinki Central Hospital.
authors.forename: Eiichiro
authors.initials: E
authors.lastname: Nakao
authors.forename: Shohei
authors.initials: S
authors.lastname: Iijima
authors.forename: Naoto
authors.initials: N
authors.lastname: Tsujimura
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Takemoto
authors.forename: Kou
authors.initials: K
authors.lastname: Takachi
authors.forename: Kiyonori
authors.initials: K
authors.lastname: Nishioka
authors.forename: Satoshi
authors.initials: S
authors.lastname: Oshima
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Uemura
authors.forename: Kyoutaro
authors.initials: K
authors.lastname: Yoshida
mesh_terms: D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D002296:Carcinosarcoma / Q000628:therapy*; D059248:Chemoradiotherapy; D004338:Drug Combinations; D004938:Esophageal Neoplasms / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000627:therapeutic use*; D005641:Tegafur / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid