title: The genomic CDS sandbox: An assessment among domain experts.
abstract: Genomics is a promising tool that is becoming more widely available to improve the care and treatment of individuals. While there is much assertion, genomics will most certainly require the use of clinical decision support (CDS) to be fully realized in the routine clinical setting. The National Human Genome Research Institute (NHGRI) of the National Institutes of Health recently convened an in-person, multi-day meeting on this topic. It was widely recognized that there is a need to promote the innovation and development of resources for genomic CDS such as a CDS sandbox. The purpose of this study was to evaluate a proposed approach for such a genomic CDS sandbox among domain experts and potential users. Survey results indicate a significant interest and desire for a genomic CDS sandbox environment among domain experts. These results will be used to guide the development of a genomic CDS sandbox.
authors.affiliation: Medical University of South Carolina, Charleston, SC, United States. Electronic address: aziza@musc.edu.
authors.forename: Ayesha
authors.initials: A
authors.lastname: Aziz
authors.affiliation: University of Utah, Salt Lake City, UT, United States. Electronic address: kensaku.kawamoto@utah.edu.
authors.forename: Kensaku
authors.initials: K
authors.lastname: Kawamoto
authors.affiliation: University of Utah, Salt Lake City, UT, United States. Electronic address: keilbeck@genetics.utah.edu.
authors.forename: Karen
authors.initials: K
authors.lastname: Eilbeck
authors.affiliation: Geisinger Medical Center, Danville, PA, United States. Electronic address: mswilliams1@geisinger.edu.
authors.forename: Marc S
authors.initials: MS
authors.lastname: Williams
authors.affiliation: Mayo Clinic, Rochester, MN, United States. Electronic address: Freimuth.Robert@mayo.edu.
authors.forename: Robert R
authors.initials: RR
authors.lastname: Freimuth
authors.affiliation: University of Missouri-Kansas City, MO, United States. Electronic address: hoffmanma@umkc.edu.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Hoffman
authors.affiliation: Northwestern University, Chicago, IL, United States. Electronic address: luke.rasmussen@northwestern.edu.
authors.forename: Luke V
authors.initials: LV
authors.lastname: Rasmussen
authors.affiliation: University of Maryland, Baltimore, MD, United States. Electronic address: coverby@medicine.umaryland.edu.
authors.forename: Casey L
authors.initials: CL
authors.lastname: Overby
authors.affiliation: University of Washington, Seattle, United States. Electronic address: shirtsb@uw.edu.
authors.forename: Brian H
authors.initials: BH
authors.lastname: Shirts
authors.affiliation: St. Jude Children's Research Hospital, Memphis, TN, United States. Electronic address: james.hoffman@stjude.org.
authors.forename: James M
authors.initials: JM
authors.lastname: Hoffman
authors.affiliation: Medical University of South Carolina, Charleston, SC, United States. Electronic address: welchbm@musc.edu.
authors.forename: Brandon M
authors.initials: BM
authors.lastname: Welch
mesh_terms: D019295:Computational Biology; D003226:Congresses as Topic; D020000:Decision Support Systems, Clinical; D023281:Genomics / Q000379:methods*; D006801:Humans; D054560:National Human Genome Research Institute (U.S.); D012984:Software; D014481:United States
keywords: Clinical decision support systems; Genomics; Health information technology; Medical genetics; Personalized medicine