title: Gold-catalyzed chemo- and diastereoselective C(sp(2))-H functionalization of enaminones for the synthesis of pyrrolo[3,4-c]-quinolin-1-one derivatives.
abstract: An efficient tandem Au(i)/TsOH-catalyzed reaction of enaminones with diazo compounds for the synthesis of pyrroloquinolinone derivatives under mild reaction conditions has been developed. This methodology was realized by relay actions of Au and TsOH in a one-pot multistep manner. Initially, the Au-catalyzed reaction of enaminones with diazo compounds affords chemo- and diastereoselective C(sp(2))-H functionalized products, which then undergo subsequent intramolecular cyclization/rearrangement to give pyrroloquinolinone derivatives under the catalysis of TsOH.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China. yzli@chem.ecnu.edu.cn.
authors.forename: Yulei
authors.initials: Y
authors.lastname: Zhao
authors.forename: Qizhao
authors.initials: Q
authors.lastname: Duan
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Zhou
authors.forename: Qiyi
authors.initials: Q
authors.lastname: Yao
authors.forename: Yanzhong
authors.initials: Y
authors.lastname: Li