title: Does AMH Reflect Follicle Number Similarly in Women with and without PCOS?
abstract: BACKGROUND
  Increased Anti-Mullerian Hormone in polycystic ovary syndrome, may be due to overactive follicles rather than reflect antral follicle count.
  
  
  OBJECTIVE
  Does Anti-Mullerian Hormone reflect antral follicle count similarly in women with or without polycystic ovary syndrome or polycystic ovarian morphology?
  
  
  METHODS
  Cross-sectional, case-control.
  
  
  METHODS
  Women who delivered preterm in 1999-2006. For each index woman, a woman with a term delivery was identified.
  
  
  METHODS
  Participation rate was 69%. Between 2006-2008, 262 women were included, and diagnosed to have polycystic ovary syndrome, polycystic ovarian morphology or to be normal controls.
  
  
  METHODS
  Blood tests, a clinical examination and vaginal ultrasound.
  
  
  METHODS
  Anti-Mullerian Hormone/antral follicle count-ratio, SHBG, androstenedione and insulin, to test potential influence on the Anti-Mullerian Hormone/antral follicle count -ratio.
  
  
  RESULTS
  Mean Anti-Mullerian Hormone/antral follicle count ratio in women with polycystic ovary syndrome or polycystic ovarian morphology was similar to that of the controls (polycystic ovary syndrome: 1,2 p = 0,10 polycystic ovarian morphology: 1,2, p = 0,27 Controls 1,3). Anti-Mullerian Hormone showed a positive linear correlation to antral follicle count in all groups. Multivariate analysis did not change the results.
  
  
  CONCLUSIONS
  We confirmed the positive correlation between AMH and follicle count. Anti-Mullerian Hormone seems to be a reliable predictor of antral follicle count, independent of polycystic ovary syndrome diagnosis or ovarian morphology.
authors.affiliation: Department of Endocrinology, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.|Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Sverre C
authors.initials: SC
authors.lastname: Christiansen
authors.affiliation: Department of Obstetrics and Gynaecology, Hospital of Namsos, Nord-Trøndelag Hospital Trust, Namsos, Norway.|Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Tina B
authors.initials: TB
authors.lastname: Eilertsen
authors.affiliation: Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway.|Department of Obstetrics and Gynecology, St Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.
authors.forename: Eszter
authors.initials: E
authors.lastname: Vanky
authors.affiliation: Department of Endocrinology, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.|Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Sven M
authors.initials: SM
authors.lastname: Carlsen
mesh_terms: D000328:Adult; D000735:Androstenedione / Q000097:blood; D054304:Anti-Mullerian Hormone / Q000378:metabolism*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D006080:Ovarian Follicle / Q000378:metabolism*; D010808:Physical Examination; D011085:Polycystic Ovary Syndrome / Q000473:pathology*
chemical_list: D007328:Insulin; D000735:Androstenedione; D054304:Anti-Mullerian Hormone