title: Dietary profile of patients with Stargardt's disease and Retinitis Pigmentosa: is there a role for a nutritional approach?
abstract: BACKGROUND
  Stargardt's disease (STGD) and Retinitis Pigmentosa (RP) are inherited retinal degenerations that may be affected, in opposite way, by diet.
  
  
  METHODS
  Dietary profile was assessed in 24 patients with STGD and in 56 patients with RP. We documented in only 6 out of 24 (25%) STGD patients a daily intake of vitamin A within the recommended range while 14/24 (58.3%) reported a high daily intake and 4/24 (16.7%) showed a low daily intake. With regard to RP, 4/56 (7.1%) reported to be within the recommended range, 37/56 (66.1%) reported high daily intake and 15/56 (26.8%) showed low daily intake of vitamin A.
  
  
  RESULTS
  Interestingly, STGD patients with low vitamin A intake (<600 µg RAE/day) showed significantly better visual acuity with respect to those introducing higher intake of vitamin A.
  
  
  CONCLUSIONS
  The present study suggests insuitable nutrient intakes among patients with STGD and RP, especially for daily intake of vitamin A. The results may be used to provide tailored nutritional interventions in these patients.
authors.affiliation: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.|Agency of Nutrition, University Hospital of Careggi, Florence, Italy.|Don Carlo Gnocchi Foundation Italy, Onlus IRCCS, Florence, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Sofi
authors.affiliation: Department of Surgery and Translational Medicine, Eye Clinic, University of Florence, Florence, Italy. asodi@tin.it.
authors.forename: Andrea
authors.initials: A
authors.lastname: Sodi
authors.affiliation: Department of Surgery and Translational Medicine, Eye Clinic, University of Florence, Florence, Italy.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Franco
authors.affiliation: Department of Surgery and Translational Medicine, Eye Clinic, University of Florence, Florence, Italy.
authors.forename: Vittoria
authors.initials: V
authors.lastname: Murro
authors.affiliation: Agency of Nutrition, University Hospital of Careggi, Florence, Italy.
authors.forename: Dania
authors.initials: D
authors.lastname: Biagini
authors.affiliation: Department of Surgery and Translational Medicine, Eye Clinic, University of Florence, Florence, Italy.
authors.forename: Alba
authors.initials: A
authors.lastname: Miele
authors.affiliation: Department of Surgery and Translational Medicine, Eye Clinic, University of Florence, Florence, Italy.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Abbruzzese
authors.affiliation: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
authors.forename: Dario Pasquale
authors.initials: DP
authors.lastname: Mucciolo
authors.affiliation: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.|Don Carlo Gnocchi Foundation Italy, Onlus IRCCS, Florence, Italy.
authors.forename: Gianni
authors.initials: G
authors.lastname: Virgili
authors.affiliation: Department of Surgery and Translational Medicine, Eye Clinic, University of Florence, Florence, Italy.
authors.forename: Ugo
authors.initials: U
authors.lastname: Menchini
authors.affiliation: Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.|Agency of Nutrition, University Hospital of Careggi, Florence, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Casini
authors.affiliation: Department of Surgery and Translational Medicine, Eye Clinic, University of Florence, Florence, Italy.
authors.forename: Stanislao
authors.initials: S
authors.lastname: Rizzo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004032:Diet; D004034:Diet Surveys; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000151:congenital* / Q000175:diagnosis / Q000178:diet therapy / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D012174:Retinitis Pigmentosa / Q000175:diagnosis / Q000178:diet therapy / Q000503:physiopathology*; D000080362:Stargardt Disease; D014792:Visual Acuity; D014801:Vitamin A / Q000008:administration & dosage*; D055815:Young Adult
chemical_list: D014801:Vitamin A