title: [A Case of Local Recurrence of Bile Duct Cancer Completely Responding to Chemoradiotherapy with S-1].
abstract: An 80-year-old man with common bile duct cancer was treated by pancreaticoduodenectomy with D2 lymph node dissection in October 2005. The patient presented with frequent episodes of bloody-mucous rectal discharge in July 2009. An abdominal CT demonstrated local recurrence at the hepatoduodenal ligament. We treated him with concurrent chemoradiotherapy (CRT) with single-dose S-1 chemotherapy. After 6 months, we diagnosed a complete response (CR) by follow-up CT. The patient was treated with S-1 for 3 years after the diagnosis of a CR. He is alive without disease 6 years after the diagnosis of the recurrence. Concurrent CRT with S-1 chemotherapy may be the therapy of choice for recurrence of bile duct cancer.
authors.affiliation: Dept. of Surgery and Gastroenterological Surgery, Osaka Saiseikai Izuo Hospital.
authors.forename: Keigo
authors.initials: K
authors.lastname: Yamamichi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sueyoshi
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Tatsuma
authors.initials: T
authors.lastname: Sakaguchi
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Hishikawa
authors.forename: Aiko
authors.initials: A
authors.lastname: Ueda
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsuura
authors.forename: Takashi
authors.initials: T
authors.lastname: Ozaki
authors.forename: Takuya
authors.initials: T
authors.lastname: Saito
mesh_terms: D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001650:Bile Duct Neoplasms / Q000628:therapy*; D059248:Chemoradiotherapy; D004338:Drug Combinations; D006801:Humans; D008297:Male; D010094:Oxonic Acid / Q000627:therapeutic use*; D016577:Pancreaticoduodenectomy; D012008:Recurrence; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid