title: Special Issue: Gene Conversion in Duplicated Genes.
abstract: Gene conversion is an outcome of recombination, causing non-reciprocal transfer of a DNA fragment. Several decades later than the discovery of crossing over, gene conversion was first recognized in fungi when non-Mendelian allelic distortion was observed. Gene conversion occurs when a double-strand break is repaired by using homologous sequences in the genome. In meiosis, there is a strong preference to use the orthologous region (allelic gene conversion), which causes non-Mendelian allelic distortion, but paralogous or duplicated regions can also be used for the repair (inter-locus gene conversion, also referred to as non-allelic and ectopic gene conversion). The focus of this special issue is the latter, interlocus gene conversion; the rate is lower than allelic gene conversion but it has more impact on phenotype because more drastic changes in DNA sequence are involved. [...].
authors.affiliation: Graduate University for Advanced Studies, Hayama, Kanagawa 240-0193, Japan. innan_hideki@soken.ac.jp.
authors.forename: Hideki
authors.initials: H
authors.lastname: Innan