title: Chemical constituents from fruiting bodies of Basidiomycete Perenniporia subacida.
abstract: Four new aromatic abietane diterpenoids and two new benzene derivatives, namely perenacidins A-F (1-6), have been isolated from the fruiting bodies of Basidiomycete Perenniporia subacida. The structures were elucidated by means of extensive spectroscopic methods and computational ECD method. The antifungal activities against Canidia albicans and the cytotoxic activities against four cancer cell lines (including K-562, A-549, SMMC-7721, MCF-7) were evaluated in vitro.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China; University of Chinese Academy of Sciences, Beijing 100039, PR China.
authors.forename: Chun-Nan
authors.initials: CN
authors.lastname: Wen
authors.affiliation: College of Resource and Environment, Yuxi Normal University, Yuxi 653100, PR China.
authors.forename: Dong-Bao
authors.initials: DB
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.
authors.forename: Xue
authors.initials: X
authors.lastname: Bai
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.affiliation: College of Pharmacy, South-Central University for Nationalities, Wuhan 430074, PR China.
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Li
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China; College of Pharmacy, South-Central University for Nationalities, Wuhan 430074, PR China. Electronic address: tfeng@mail.scuec.edu.cn.
authors.forename: Tao
authors.initials: T
authors.lastname: Feng
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China; College of Pharmacy, South-Central University for Nationalities, Wuhan 430074, PR China. Electronic address: jkliu@mail.kib.ac.cn.
authors.forename: Ji-Kai
authors.initials: JK
authors.lastname: Liu
mesh_terms: D045784:Abietanes / Q000737:chemistry* / Q000302:isolation & purification; D001487:Basidiomycota / Q000737:chemistry*; D002176:Candida albicans / Q000187:drug effects; D045744:Cell Line, Tumor; D048690:Fruiting Bodies, Fungal / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure
chemical_list: D045784:Abietanes
keywords: Abietane diterpenoids; Antifungal activities; Cytotoxic activities; Perenniporia subacida