title: Anterior chamber aqueous flare, pseudoexfoliation syndrome, and glaucoma.
abstract: The purpose of this study is to evaluate anterior chamber aqueous flare (ACAF) in Tunisian patients with pseudoexfoliation (PEX) syndrome with or without associated glaucoma. This is a prospective, cross-sectional, comparative study including 53 patients (88 eyes) with PEX syndrome, 48 patients with PEX glaucoma (86 eyes), and 53 healthy sex-and age-matched control subjects (106 eyes). All patients underwent a complete ophthalmic examination and laser flare photometry. Mean ACAF was significantly higher in the PEX syndrome group in comparison with the control group (17.96 ± 10.05 vs 7.06 ± 2.95 ph/ms; p = 10(-4)), in patients with PEX glaucoma compared to PEX syndrome without associated glaucoma (27.99 ± 15.45 vs 17.96 ± 10.05 ph/ms; p = 10(-4)), in the PEX glaucoma group in comparison with control group (27.99 ± 15.45 vs 7.06 ± 2.95 ph/ms; p = 10(-4)), and in patients with unilateral PEX syndrome in comparison with contralateral-unaffected eyes (25.72 ± 14.88 vs 8.58 ± 3.45 ph/ms; p = 0.000). For patients with PEX syndrome, a high ACAF might be a predictor for the development of glaucoma. Further investigations are needed to clarify the role of laser flare photometry in predicting the risk of glaucoma in patients with PEX syndrome.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5019, Monastir, Tunisia.
authors.forename: Rim
authors.initials: R
authors.lastname: Kahloun
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5019, Monastir, Tunisia.
authors.forename: Sonia
authors.initials: S
authors.lastname: Attia
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5019, Monastir, Tunisia.
authors.forename: Imen
authors.initials: I
authors.lastname: Ksiaa
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5019, Monastir, Tunisia.
authors.forename: Ilhem
authors.initials: I
authors.lastname: Kacem
authors.affiliation: Department of Community and Preventive Medicine, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.
authors.forename: Ines
authors.initials: I
authors.lastname: Bouanene
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5019, Monastir, Tunisia.
authors.forename: Sonia
authors.initials: S
authors.lastname: Zaouali
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5019, Monastir, Tunisia.
authors.forename: Bechir
authors.initials: B
authors.lastname: Jelliti
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5019, Monastir, Tunisia. moncef.khairallah@yahoo.fr.
authors.forename: Moncef
authors.initials: M
authors.lastname: Khairallah
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001082:Aqueous Humor; D018916:Blood-Aqueous Barrier / Q000502:physiology; D003430:Cross-Sectional Studies; D017889:Exfoliation Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D010783:Photometry / Q000379:methods; D011446:Prospective Studies; D014065:Tonometry, Ocular
chemical_list: D000959:Antihypertensive Agents
keywords: Glaucoma; Laser flare photometry; Pseudoexfoliation syndrome