title: [Hospital incidence, trends and municipal distribution of prostate cancer in health area of León, Spain (1996-2010)].
abstract: BACKGROUND
  Prostate cancer (PC) is the most prevalent among men and yet its risk factors are little known. This article aims to determine the hospital incidence, trend and municipal distribution of PC in Health Area of León (HAL).
  
  
  METHODS
  We included new cases of prostate cancer (ICD-9: 185, ICD-10: C61) enrolled in the Hospital Tumor Registry of the Complejo Asistencial Universitario de León, between 1996 to 2010 with residence in HAL. We calculated crude triennial hospital incidences and adjusted at global and European population. As denominator we used the INE population data disaggregated by five-year age groups of residents in municipalities of the HAL. To analyze the spatial distribution, we estimated municipal relative risks (RR) smoothed by fitting the Besag, York and Mollié model and the posterior probability (PP) of RR >1 using Bayesian methods.
  
  
  RESULTS
  3,366 cases were included. Standardized rates at European population amounted of 30.3 (1996-98) to 119.0 (2008-2010) new cases per 100,000 men. The number of organ-confined cases were increased from 281 (1999-2001) to 999 (2008-2010). PSA determinations amounted from 30,985 (1999-2001) to 117 396 (2008-2010).
  
  
  CONCLUSIONS
  A great increase was observed in the frequency of PC at the expense of organ-confined cases which correlate very well with PSA determinations performed in HAL. There were no differences of interest in the municipal distribution incidences.
authors.forename: Vicente
authors.initials: V
authors.lastname: Martín Sánchez
authors.forename: Miguel
authors.initials: M
authors.lastname: García-Sanz
authors.forename: Lidia
authors.initials: L
authors.lastname: García-Martínez
authors.forename: Marbella
authors.initials: M
authors.lastname: Del Canto Cabero
authors.forename: Francisco
authors.initials: F
authors.lastname: Campanario-Pérez
authors.forename: Paquita
authors.initials: P
authors.lastname: González Sevilla
authors.forename: Lorena
authors.initials: L
authors.lastname: Estévez Iglesias
authors.forename: Emiliano
authors.initials: E
authors.lastname: Honrado Franco
authors.forename: Ana
authors.initials: A
authors.lastname: Cuesta-Díaz de Rada
authors.forename: Fructuoso
authors.initials: F
authors.lastname: García Díez
authors.forename: Gonzalo
authors.initials: G
authors.lastname: López-Abente
mesh_terms: D000328:Adult; D000368:Aged; D001499:Bayes Theorem; D002947:Cities / Q000453:epidemiology*; D006761:Hospitals / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D011471:Prostatic Neoplasms / Q000453:epidemiology*; D013030:Spain / Q000453:epidemiology; D014504:Urban Health / Q000706:statistics & numerical data*; D055815:Young Adult