title: [Pathogenesis and clinical manifestations of sporadic cerebral small vessel disease].
abstract: Sporadic small vessel disease (sSVD) is one of the most common vascular disease of the central nervous system (CNS). It is the main cause of lacunar stokes, hemorrhages to deep brain regions and chronic CNS diseases such as vascular parkinsonism and dementia. Beside a high and growing incidence of sSVD especially in the elderly population, the knowledge of ethiopathogenesis and optimal treatment of sSVD have not been established. The article summarizes different clinical manifestations (acute and chronic) as well as heterogenous radiologic changes found in CNS neuroimaging.
authors.affiliation: Military Institute of Medicine in Warsaw, Central Clinical Hospital of the Ministry of National Defense: Department of Neurology.
authors.forename: Jacek
authors.initials: J
authors.lastname: Staszewski
authors.affiliation: Military Institute of Medicine in Warsaw, Central Clinical Hospital of the Ministry of National Defense: Department of Neurology.
authors.forename: Renata
authors.initials: R
authors.lastname: Piusińska-Macoch
authors.affiliation: Military Institute of Medicine in Warsaw, Central Clinical Hospital of the Ministry of National Defense: Department of Medical Radiology.
authors.forename: Ewa
authors.initials: E
authors.lastname: Skrobowska
authors.affiliation: Military Institute of Medicine in Warsaw, Central Clinical Hospital of the Ministry of National Defense: Department of Ophtalmology.
authors.forename: Rafał
authors.initials: R
authors.lastname: Pawlik
authors.affiliation: Military Institute of Medicine in Warsaw, Central Clinical Hospital of the Ministry of National Defense: Department of Neurology.
authors.forename: Bogdan
authors.initials: B
authors.lastname: Brodacki
authors.affiliation: Military Institute of Medicine in Warsaw, Central Clinical Hospital of the Ministry of National Defense: Department of Neurology.
authors.forename: Adam
authors.initials: A
authors.lastname: Stępień
mesh_terms: D000368:Aged; D059345:Cerebral Small Vessel Diseases / Q000150:complications / Q000175:diagnosis* / Q000209:etiology*; D015140:Dementia, Vascular / Q000209:etiology; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology; D059906:Neuroimaging; D059409:Stroke, Lacunar / Q000209:etiology
keywords: cerebral small vessel disease; clinical syndromes; pathogenesis; white matter hyperintensities