title: Synthesis and evaluation of a desymmetrised synthetic lectin: an approach to carbohydrate receptors with improved versatility.
abstract: A new synthetic lectin features apolar surfaces provided by two different aromatic components (biphenyl and pyrenyl). Affinities up to 260 M(-1) are recorded for carbohydrates in water. The desymmetrised design has potential for variation to give receptors with a broadened range of capabilities.
authors.affiliation: School of Chemistry, University of Bristol, Cantock's Close, BS8 1TS, Bristol, UK. tiddomooibroek@gmail.com anthony.davis@bristol.ac.uk.
authors.forename: Tiddo J
authors.initials: TJ
authors.lastname: Mooibroek
authors.affiliation: School of Chemistry, University of Bristol, Cantock's Close, BS8 1TS, Bristol, UK. tiddomooibroek@gmail.com anthony.davis@bristol.ac.uk.
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Crump
authors.affiliation: School of Chemistry, University of Bristol, Cantock's Close, BS8 1TS, Bristol, UK. tiddomooibroek@gmail.com anthony.davis@bristol.ac.uk.
authors.forename: Anthony P
authors.initials: AP
authors.lastname: Davis
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D006801:Humans; D037102:Lectins / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D066244:Proton Magnetic Resonance Spectroscopy; D014867:Water / Q000737:chemistry
chemical_list: D002241:Carbohydrates; D037102:Lectins; D014867:Water