title: The Effect of Laser Trabeculoplasty on Posture-Induced Intraocular Pressure Changes in Patients with Open Angle Glaucoma.
abstract: OBJECTIVE
  To investigate the effect of argon laser trabeculoplasty (ALT) on posture-induced intraocular pressure (IOP) changes in patients with open angle glaucoma (OAG).
  
  
  METHODS
  Thirty eyes of 30 consecutive patients with OAG who underwent ALT were prospectively analyzed. The IOP was measured using Icare PRO in the sitting position, supine position, and dependent lateral decubitus position (DLDP) before ALT and at 1 week, 1 month, 2 months, and 3 months after ALT.
  
  
  RESULTS
  Compared to the baseline values, the IOP in each position was significantly decreased after ALT (all P < 0.001). During follow-up, the mean percentage of IOP reduction was similar in the sitting and supine positions, but was significantly lower in DLDP than in the sitting or supine positions (all P < 0.05). In terms of postural IOP changes, the IOP in the supine position and DLDP was significantly higher than that in the sitting position at the same time points during the follow-up period (all P < 0.001). The difference between the IOP in the supine position and DLDP during follow-up was significant (all P < 0.001). The extent of IOP differences between any positions did not show significant changes during the follow-up period (all P > 0.05).
  
  
  CONCLUSIONS
  ALT appears to be effective in lowering the IOP in various body positions, but the degree of this effect was significantly lower in DLDP. In addition, ALT seemed to have limited effects on posture-induced IOP changes.
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwang-ju, Republic of Korea.
authors.forename: Jee Myung
authors.initials: JM
authors.lastname: Yang
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwang-ju, Republic of Korea.
authors.forename: Mi Sun
authors.initials: MS
authors.lastname: Sung
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwang-ju, Republic of Korea.
authors.forename: Hwan
authors.initials: H
authors.lastname: Heo
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwang-ju, Republic of Korea.|Center for Creative Biomedical Scientists, Chonnam National University, Gwang-ju, Republic of Korea.
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011187:Posture / Q000502:physiology*; D011446:Prospective Studies; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome