title: Visible-Light-Mediated Photocatalytic Difunctionalization of Olefins by Radical Acylarylation and Tandem Acylation/Semipinacol Rearrangement.
abstract: A novel method for the mild photoredox-mediated tandem radical acylarylation and tandem acylation/semipinacol rearrangement has been developed. The synthesis of highly functionalized ketones bearing all-carbon α- or β-quaternary centers has been achieved using easily available symmetric aromatic carboxylic anhydrides as the acyl radical source. The method allows for a straightforward introduction of the keto functionality and concomitant construction of molecular complexity in a single operation.
authors.affiliation: Department of Chemistry and Molecular Biology, Gothenburg University, 412 58, Gothenburg, Sweden.
authors.forename: Giulia
authors.initials: G
authors.lastname: Bergonzini
authors.affiliation: Department of Chemistry and Molecular Biology, Gothenburg University, 412 58, Gothenburg, Sweden.
authors.forename: Carlo
authors.initials: C
authors.lastname: Cassani
authors.affiliation: Department of Chemistry and Molecular Biology, Gothenburg University, 412 58, Gothenburg, Sweden.
authors.forename: Haldor
authors.initials: H
authors.lastname: Lorimer-Olsson
authors.affiliation: Department of Chemistry and Molecular Biology, Gothenburg University, 412 58, Gothenburg, Sweden.
authors.forename: Johanna
authors.initials: J
authors.lastname: Hörberg
authors.affiliation: Department of Chemistry and Molecular Biology, Gothenburg University, 412 58, Gothenburg, Sweden. carl.wallentin@chem.gu.se.
authors.forename: Carl-Johan
authors.identifier: http://orcid.org/0000-0003-1983-9378
authors.initials: CJ
authors.lastname: Wallentin
keywords: acylation; cyclization; oxindole; photoredox catalysis; synthetic methods