title: Management of Penile Cancer.
abstract: Although rare, penile cancer carries high morbidity and mortality particularly when pertaining to the management of locally advanced or metastatic disease. The current scientific literature lacks level 1 evidence and current guidelines are based largely on retrospective studies and small single center studies. Despite these limitations, there has been paradigm shifts in the management of both local and systemic disease. Current guidelines emphasize penile sparing strategies, minimizing morbidity from surgical management of loco-regional metastasis and multimodal management of bulky inguinal lymph node metastases. The present review highlights the current state of knowledge and recommended treatment strategies of penile carcinoma.
authors.affiliation: Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL.
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Diorio
authors.affiliation: Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL.
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Leone
authors.affiliation: Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL. Electronic address: philippe.spiess@moffitt.org.
authors.forename: Philippe E
authors.initials: PE
authors.lastname: Spiess
mesh_terms: D003663:Decision Trees; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D010412:Penile Neoplasms / Q000473:pathology / Q000628:therapy*; D017410:Practice Guidelines as Topic; D013521:Urologic Surgical Procedures, Male / Q000379:methods