title: [Short-course antibiotic regimens: Up-to-date].
abstract: Antibiotic treatment durations are not well documented. Yet, dramatic emergence of multi-drug resistant organisms should lead to tend to decrease antibiotic selection pressure. Furthermore, it could lower health costs and reduce associated adverse events. Unfortunately, only few studies with rigorous methodology have been performed. We present the available data on frequent infections such as urinary tract infections, community acquired pneumonia, bone and joint infections and intra-abdominal infections. We underline the difficulties to perform such trials and discuss original options to a better evaluation of treatment duration.
authors.affiliation: Unité des maladies infectieuses, hôpitaux universitaires Paris-Île-de-France Ouest, CHU Raymond-Poincaré, 104, boulevard Raymond-Poincaré, 92380 Garches, France. Electronic address: aurelien.dinh@aphp.fr.
authors.forename: A
authors.initials: A
authors.lastname: Dinh
authors.affiliation: Service de pharmacie, hôpitaux universitaires Paris-Île-de-France Ouest, CHU Raymond-Poincaré, 104, boulevard Raymond-Poincaré, 92380 Garches, France.
authors.forename: F
authors.initials: F
authors.lastname: Bouchand
authors.affiliation: Unité des maladies infectieuses, hôpitaux universitaires Paris-Île-de-France Ouest, CHU Raymond-Poincaré, 104, boulevard Raymond-Poincaré, 92380 Garches, France.
authors.forename: J
authors.initials: J
authors.lastname: Salomon
authors.affiliation: Service de médecine interne et maladies infectieuses, université F.-Rabelais, CHRU Bretonneau, 2 bis, boulevard Tonnellé, 37044 Tours cedex, France.
authors.forename: L
authors.initials: L
authors.lastname: Bernard
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D024881:Drug Resistance, Bacterial / Q000187:drug effects*; D006801:Humans; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents
keywords: Adapted use of antibiotics; Antibiotiques; Antimicrobial therapy; Bon usage; Durée de traitement; Multi-drug resistant organism; Résistances bactériennes; Treatment duration