title: Solid-type primary intraosseous squamous-cell carcinoma in the mandible: Report of a rare case.
abstract: Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare malignant neoplasm that has an exquisitely exclusive affection to the jawbone. It is defined as squamous cell carcinoma arising within the jaw and developing from residual odontogenic epithelium or from a preexisting odontogenic cyst or tumor. The solid-type of this tumor is a central jaw carcinoma arising de novo and has no initial connection with the oral mucosa. Herein, we report a case of solid-type PIOSCC involving the mandible in a 37-year-old male patient elucidating its histopathological and imaging findings. The patient underwent surgical resection followed by post-operative adjuvant radiotherapy. The close 2-year follow up of the patient revealed neither locoregional nor distant metastasis.
authors.affiliation: Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia. Electronic address: drotaibi@ksu.edu.sa.
authors.forename: Ohoud
authors.initials: O
authors.lastname: Alotaibi
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
authors.forename: Nabil
authors.initials: N
authors.lastname: Al-Zaher
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
authors.forename: Faiza
authors.initials: F
authors.lastname: Alotaibi
authors.affiliation: Department of Pathology, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
authors.forename: Hatim
authors.initials: H
authors.lastname: Khoja
authors.affiliation: Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Qannam
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed
keywords: Intraosseous neoplasms; Mandible; Primary intraosseous squamous cell carcinoma; Solid type