title: Population genetic structure of urban malaria vector Anopheles stephensi in India.
abstract: Malaria is a major public health problem in India because climatic condition and geography of India provide an ideal environment for development of malaria vector. Anopheles stephensi is a major urban malaria vector in India and its control has been hampered by insecticide resistance. In present study population genetic structure of A. stephensi is analyzed at macro geographic level using 13 microsatellite markers. Significantly high genetic differentiation was found in all studied populations with differentiation values (FST) ranging from 0.0398 to 0.1808. The geographic distance was found to be playing a major role in genetic differentiation between different populations. Overall three genetic pools were observed and population of central India was found to be coexisting in two genetic pools. High effective population size (Ne) was found in all the studied populations.
authors.affiliation: Centre for Biotechnology, M.D. University, Rohtak, Haryana-124001, India.
authors.forename: Richa
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Centre for Biotechnology, M.D. University, Rohtak, Haryana-124001, India.
authors.forename: Arvind
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Centre for Biotechnology, M.D. University, Rohtak, Haryana-124001, India.
authors.forename: Ashwani
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Department of Statistics, M.D. University, Rohtak, Haryana-124001, India.
authors.forename: Madhulika
authors.initials: M
authors.lastname: Dube
authors.affiliation: Centre for Biotechnology, M.D. University, Rohtak, Haryana-124001, India. Electronic address: surengak@gmail.com.
authors.forename: S K
authors.initials: SK
authors.lastname: Gakhar
mesh_terms: D000818:Animals; D000852:Anopheles / Q000145:classification* / Q000235:genetics*; D014644:Genetic Variation; D005828:Genetics, Population; D006801:Humans; D007194:India / Q000453:epidemiology; D007305:Insecticide Resistance; D008288:Malaria / Q000635:transmission*; D018895:Microsatellite Repeats; D058974:Phylogeography; D011156:Population Density
keywords: An. stephensi; Differentiation; Effective population size; Genetic pool; Malaria