title: Enhanced chemiluminescence-based detection on gold substrate after electrografting of diazonium precursor-coated gold nanoparticles.
abstract: Since it was demonstrated that nanostructured surfaces are more efficient for the detection based on the specific capture of analytes, there is a real need to develop strategies for grafting nanoparticles onto flat surfaces. Among the different routes for the functionalization of a surface, the reduction of diazonium salts appears very attractive for the covalent immobilization of nanoparticles because this method does not require a pre-treatment of the surface. For achieving this goal, gold nanoparticles coated by precursor of diazonium salts were synthesized by reduction of gold salt in presence of mercaptoaniline. These mercaptoaniline-coated gold nanoparticles (Au@MA) were successfully immobilized onto various conducting substrates (indium tin oxide (ITO), glassy carbon (GC) and gold electrodes with flat terraces) after addition of sodium nitrite at fixed potential. When applied onto the gold electrodes, such a grafting strategy led to an obvious enhancement of the luminescence of luminol used for the biodetection.
authors.affiliation: Institut UTINAM, UMR 6213 CNRS-Université de Franche-Comté, 25030 Besançon Cedex, France. Electronic address: alialfred@hotmail.com.
authors.forename: Ali
authors.initials: A
authors.lastname: Houmed Adabo
authors.affiliation: Institut FEMTO-ST, UMR 6174 CNRS-Université de Franche-Comté, 25044 Besançon Cedex, France. Electronic address: rabah.zeggari@femto-st.fr.
authors.forename: Rabah
authors.initials: R
authors.lastname: Zeggari
authors.affiliation: Institut UTINAM, UMR 6213 CNRS-Université de Franche-Comté, 25030 Besançon Cedex, France. Electronic address: said.nasser_mohamed@univ-fcomte.fr.
authors.forename: Nasser
authors.initials: N
authors.lastname: Mohamed Saïd
authors.affiliation: Institut UTINAM, UMR 6213 CNRS-Université de Franche-Comté, 25030 Besançon Cedex, France. Electronic address: rana.bazzi@univ-fcomte.fr.
authors.forename: Rana
authors.initials: R
authors.lastname: Bazzi
authors.affiliation: Institut FEMTO-ST, UMR 6174 CNRS-Université de Franche-Comté, 25044 Besançon Cedex, France. Electronic address: celine.caille@femto-st.fr.
authors.forename: Céline
authors.initials: C
authors.lastname: Elie-Caille
authors.affiliation: Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, UMR 5246 CNRS-Université Lyon 1, 69622 Villeurbanne Cedex, France. Electronic address: christophe.marquette@univ-lyon1.fr.
authors.forename: Christophe
authors.initials: C
authors.lastname: Marquette
authors.affiliation: Institut Lumière Matière, UMR 5306 CNRS-Université Lyon 1, 69622 Villeurbanne Cedex, France. Electronic address: matteo.martini@univ-lyon1.fr.
authors.forename: Matteo
authors.initials: M
authors.lastname: Martini
authors.affiliation: Institut Lumière Matière, UMR 5306 CNRS-Université Lyon 1, 69622 Villeurbanne Cedex, France. Electronic address: olivier.tillement@univ-lyon1.fr.
authors.forename: Olivier
authors.initials: O
authors.lastname: Tillement
authors.affiliation: Matériaux Ingénierie et Science, UMR 5510 CNRS-INSA de Lyon, 69621 Villeurbanne Cedex, France. Electronic address: pascal.perriat@insa-lyon.fr.
authors.forename: Pascal
authors.initials: P
authors.lastname: Perriat
authors.affiliation: Institut des Sciences Analytiques, UMR 5280 CNRS-Université de Lyon 1, 69100 Villeurbanne Cedex, France. Electronic address: carole.chaix-bauvais@univ-lyon1.fr.
authors.forename: Carole
authors.initials: C
authors.lastname: Chaix
authors.affiliation: Institut FEMTO-ST, UMR 6174 CNRS-Université de Franche-Comté, 25044 Besançon Cedex, France. Electronic address: wilfrid.boireau@femto-st.fr.
authors.forename: Wilfrid
authors.initials: W
authors.lastname: Boireau
authors.affiliation: Institut UTINAM, UMR 6213 CNRS-Université de Franche-Comté, 25030 Besançon Cedex, France. Electronic address: stephane.roux@univ-fcomte.fr.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Roux
mesh_terms: D003979:Diazonium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D055664:Electrochemical Techniques; D004566:Electrodes; D006046:Gold / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D049449:Luminescence; D008163:Luminescent Measurements / Q000379:methods*; D053768:Metal Nanoparticles / Q000737:chemistry*; D050607:Organogold Compounds / Q000032:analysis*; D010316:Particle Size; D013499:Surface Properties
chemical_list: D003979:Diazonium Compounds; D050607:Organogold Compounds; D006046:Gold
keywords: Electrochemical grafting; Nanoparticles; Sensor