title: Cerebellar role in Parkinson's disease.
abstract: Parkinson's disease (PD) is a common neurodegenerative disorder associated with motor and cognitive impairments. The mechanisms underlying the pathophysiology and treatments have traditionally focused on basal ganglia-thalamo-cortical pathways due to striatal dopamine loss, but more recent evidence has highlighted the role of the cerebellum. In this Neuro Forum article, I review evidence from neuroimaging and noninvasive brain stimulation that demonstrates altered cerebellar activity in PD may be both a pathophysiological and compensatory mechanism depending on dopaminergic medication and symptoms.
authors.affiliation: Department of Kinesiology, School of Public Health, Indiana University, Bloomington, Indiana jmirdama@indiana.edu.
authors.forename: Jasmine L
authors.initials: JL
authors.lastname: Mirdamadi
mesh_terms: D002531:Cerebellum / Q000503:physiopathology*; D006801:Humans; D009434:Neural Pathways / Q000502:physiology; D010300:Parkinson Disease / Q000473:pathology* / Q000503:physiopathology
keywords: Parkinson's disease; brain stimulation; cerebellum; functional connectivity