title: Identification and characterization of new designer drug 4-fluoro-PV9 and α-PHP in the seized materials.
abstract: In this study, we present identification and physicochemical characterization of new cathinone derivatives, 4-fluoro-PV9 and already known α-PHP in seized materials. Although the disclosure of α-PHP from an illegal product had been reported and characterized to some extent, the data on α-PHP are also presented together with those of 4-fluoro-PV9. The data of characterization for the two compounds were obtained by high-performance liquid chromatography (HPLC)-mass spectrometry and HPLC-diode array detection, electrospray ionization/ion trap mass spectrometry in MS2and MS3modes, gas chromatography-mass spectrometry, thermogravimetric analysis, differential scanning calorimetry, Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, and nuclear magnetic resonance spectroscopy. To our knowledge, this is the first report for identification and detailed characterization of 4-fluoro-PV9 circulated on the illegal drug market.
authors.affiliation: Department of General Chemistry and Chromatography, Institute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, Poland ; Toxicology Laboratory ToxLab, 6 Kossutha Street, 40-844 Katowice, Poland.
authors.forename: Milena
authors.initials: M
authors.lastname: Majchrzak
authors.affiliation: Department of Organic Synthesis, Institute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, Poland ; Toxicology Laboratory ToxLab, 6 Kossutha Street, 40-844 Katowice, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Rojkiewicz
authors.affiliation: Toxicology Laboratory ToxLab, 6 Kossutha Street, 40-844 Katowice, Poland.
authors.forename: Rafał
authors.initials: R
authors.lastname: Celiński
authors.affiliation: Department of Organic Synthesis, Institute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Kuś
authors.affiliation: Department of General Chemistry and Chromatography, Institute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, Poland.
authors.forename: Mieczysław
authors.initials: M
authors.lastname: Sajewicz
keywords: 4-Fluoro-PV9; Designer drugs; ESI-MS/MS; GC–MS; NMR; α-PHP