title: Genome-Wide Analysis of NBS-LRR Genes in Sorghum Genome Revealed Several Events Contributing to NBS-LRR Gene Evolution in Grass Species.
abstract: The nucleotide-binding site (NBS)-leucine-rich repeat (LRR) gene family is crucially important for offering resistance to pathogens. To explore evolutionary conservation and variability of NBS-LRR genes across grass species, we identified 88, 107, 24, and 44 full-length NBS-LRR genes in sorghum, rice, maize, and Brachypodium, respectively. A comprehensive analysis was performed on classification, genome organization, evolution, expression, and regulation of these NBS-LRR genes using sorghum as a representative of grass species. In general, the full-length NBS-LRR genes are highly clustered and duplicated in sorghum genome mainly due to local duplications. NBS-LRR genes have basal expression levels and are highly potentially targeted by miRNA. The number of NBS-LRR genes in the four grass species is positively correlated with the gene clustering rate. The results provided a valuable genomic resource and insights for functional and evolutionary studies of NBS-LRR genes in grass species.
authors.affiliation: Agronomy Department, University of Florida, Gainesville, FL, USA.
authors.forename: Xiping
authors.initials: X
authors.lastname: Yang
authors.affiliation: Agronomy Department, University of Florida, Gainesville, FL, USA.; Plant Molecular and Cellular Biology Program, Genetics Institute, University of Florida, Gainesville, FL, USA.; FAFU and UIUC-SIB Joint Center for Genomics and Biotechnology, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Wang
keywords: NBS-LRR; disease resistance gene; evolution; grass species; local duplication