title: The successful use of amphotericin B followed by oral posaconazole in a rare case of invasive fungal sinusitis caused by co-infection with mucormycosis and aspergillus.
abstract: We report on an unusual case of oro-rhinocerebral disease caused by mucormycosis and aspergillus co-infection in a 54-year-old insulin dependent diabetic patient. Although she was successfully treated with parenteral amphotericin B followed by oral posaconazole, she was left with irreversible blindness of the right eye and multiple cranial nerve palsies.
authors.affiliation: National Health Laboratory Services, Department of Medical Microbiology, Inkosi Albert Luthuli Central Hospital, Durban, KwaZulu Natal, South Africa; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Sharana
authors.initials: S
authors.lastname: Mahomed
authors.affiliation: Department of Ear, Nose and Throat, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Sujith
authors.initials: S
authors.lastname: Basanth
authors.affiliation: National Health Laboratory Services, Department of Medical Microbiology, Inkosi Albert Luthuli Central Hospital, Durban, KwaZulu Natal, South Africa; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Koleka
authors.initials: K
authors.lastname: Mlisana
keywords: Amphotericin B; Aspergillus; Co-infection; Mucormycosis; Posaconazole