title: Perinatal Neuroprotection for Extremely Preterm Infants.
abstract: The preterm brain is vulnerable to injury through multiple mechanisms, from direct cerebral injury through ischemia and hemorrhage, indirect injury through inflammatory processes, and aberrations in growth and development. While prevention of preterm birth is the best neuroprotective strategy, this is not always possible. This article will review various obstetric and neonatal practices that have been shown to confer a neuroprotective effect on the developing brain.
authors.affiliation: Division of Neonatal-Developmental Medicine, Stanford University, Palo Alto, California.
authors.forename: Alexis S
authors.initials: AS
authors.lastname: Davis
authors.affiliation: Division of Maternal-Fetal Medicine, University of California, San Francisco, San Francisco, California.
authors.forename: Victoria K
authors.initials: VK
authors.lastname: Berger
authors.affiliation: Division of Neonatal-Developmental Medicine, Stanford University, Palo Alto, California.
authors.forename: Valerie Y
authors.initials: VY
authors.lastname: Chock
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D001930:Brain Injuries / Q000517:prevention & control; D005260:Female; D006801:Humans; D062071:Infant, Extremely Premature / Q000254:growth & development*; D007231:Infant, Newborn; D008278:Magnesium Sulfate / Q000627:therapeutic use; D000066829:Neuroprotection / Q000187:drug effects*; D036801:Parturition; D011181:Postnatal Care / Q000379:methods*; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D047928:Premature Birth / Q000517:prevention & control*; D011295:Prenatal Care / Q000592:standards*; D016032:Randomized Controlled Trials as Topic
chemical_list: D000305:Adrenal Cortex Hormones; D008278:Magnesium Sulfate