title: [Colorectal Cancer with Macroscopic Invasion to Adjacent Organs--A Case Report].
abstract: We encountered a case of colorectal cancer with macroscopic invasion to the adjacent organs. A 61-year-old man with abdominal pain and nausea was diagnosed as having sigmoid colon cancer invading the ileum, ureter, internal iliac artery, and external iliac vein. A lower anterior resection and resection of the small bowel, ureter, external iliac vein, and internal iliac artery was performed and succeeded in an R0 resection. The patient was discharged from the hospital in 29 POD. Pathology results revealed an adenocarcinoma, pT4b, pSI, INF b, int, ly0, v, pPM0, pDM0, pN0, Type 2, Stage Ⅱ. Four courses of XELOX plus bevacizumab were administered. The patient underwent ileostomy closure, and is currently free of relapse 3 years 2 months after resection. The survival rate of patients with combined resection of the invaded organs is significantly higher than that of patients with a non-combined resection. The survival rate after curative resection is also significantly higher compared with non-curative resection. Aggressive resection of invaded organs seems to be important for a good outcome.
authors.affiliation: Dept. of Surgery, Niigata Prefectural Tokamachi Hospital.
authors.forename: Yudai
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Hayashi
authors.forename: Tomotaka
authors.initials: T
authors.lastname: Kato
authors.forename: Keisuke
authors.initials: K
authors.lastname: Nakao
authors.forename: Chisato
authors.initials: C
authors.lastname: Okajima
authors.forename: Kenji
authors.initials: K
authors.lastname: Shitara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fukunari
authors.forename: Gen
authors.initials: G
authors.lastname: Watanabe
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D006801:Humans; D045823:Ileus / Q000209:etiology / Q000601:surgery; D007421:Intestine, Small / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012811:Sigmoid Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D059016:Tumor Microenvironment