title: Naturally occurring amino acid derivatives with herbicidal, fungicidal or insecticidal activity.
abstract: Several naturally occurring amino acid derivatives display significant activities against weeds, fungi and insects: some of them have been even commercialized and are applied as crop protection agents. The 53 most important amino acid natural products with such efficacy are presented in this review together with their natural source, mode of action and biological activity. The diversity of the manifold bacterial, fungal and plantal sources of these compounds is impressive as well as their completely different structural scaffolds, ranging from cyclopeptides via unique non-proteinogenic amino acids to peptidyl nucleosides, the broad range of target enzymes from several different biochemical pathways, which they inhibit and also the plethora of different weeds, fungi and insects they are able to control.
authors.affiliation: Syngenta Crop Protection AG, Stein, Switzerland. clemens.lamberth@syngenta.com.
authors.forename: Clemens
authors.initials: C
authors.lastname: Lamberth
mesh_terms: D000596:Amino Acids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018556:Crops, Agricultural / Q000382:microbiology / Q000469:parasitology; D005658:Fungi / Q000187:drug effects / Q000201:enzymology / Q000254:growth & development; D005659:Fungicides, Industrial / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006540:Herbicides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007300:Insect Control / Q000379:methods; D007303:Insect Vectors / Q000187:drug effects / Q000201:enzymology / Q000254:growth & development; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009705:Nucleosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D057685:Plant Weeds / Q000187:drug effects / Q000201:enzymology / Q000254:growth & development
chemical_list: D000596:Amino Acids; D001688:Biological Products; D005659:Fungicides, Industrial; D006540:Herbicides; D007306:Insecticides; D009705:Nucleosides; D010456:Peptides, Cyclic
keywords: Agrochemicals; Amino acids; Crop protection; Fungicides; Herbicides; Insecticides; Natural products