title: Excited-state intramolecular proton transfer of 2-acetylindan-1,3-dione studied by ultrafast absorption and fluorescence spectroscopy.
abstract: We employ transient absorption from the deep-UV to the visible region and fluorescence upconversion to investigate the photoinduced excited-state intramolecular proton-transfer dynamics in a biologically relevant drug molecule, 2-acetylindan-1,3-dione. The molecule is a ß-diketone which in the electronic ground state exists as exocyclic enol with an intramolecular H-bond. Upon electronic excitation at 300 nm, the first excited state of the exocyclic enol is initially populated, followed by ultrafast proton transfer (≈160 fs) to form the vibrationally hot endocyclic enol. Subsequently, solvent-induced vibrational relaxation takes place (≈10 ps) followed by decay (≈390 ps) to the corresponding ground state.
authors.affiliation: Institut für Physikalische und Theoretische Chemie, Universität Würzburg , Am Hubland, 97074 Würzburg, Germany.
authors.forename: Pramod Kumar
authors.initials: PK
authors.lastname: Verma
authors.affiliation: Institut für Physikalische und Theoretische Chemie, Universität Würzburg , Am Hubland, 97074 Würzburg, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Steinbacher
authors.affiliation: Institut für Organische Chemie, Universität Würzburg , Am Hubland, 97074 Würzburg, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Schmiedel
authors.affiliation: Physikalische Chemie II, Ruhr-Universität Bochum , 44780 Bochum, Germany.
authors.forename: Patrick
authors.initials: P
authors.lastname: Nuernberger
authors.affiliation: Institut für Physikalische und Theoretische Chemie, Universität Würzburg , Am Hubland, 97074 Würzburg, Germany.
authors.forename: Tobias
authors.initials: T
authors.lastname: Brixner