title: [The fertility-associated treatment of young breast cancer patients].
abstract: There is no treatment norm on the fertility issue of breast cancer patients. The clinical studies show that the effects of chemotherapy and endocrine treatment on menstrual cycle and ovarian function have connection with patients' age, therapeutic regimen and drug dose. The time to be pregnant should be decided according to the stage of tumor and the therapeutic regimen. The trimester of pregnancy and tumor stage should be considered when making the therapeutic regimen for the breast cancer patients during pregnancy. And it is not recommended to choose the induced abortion for the therapeutic aim. Theoretically, ovarian function inhibition drugs have great application prospects, while, of which the long-term affect on human body and the relation with tumor development need more researches to study. The available evidence-based practices consider that the pregnancy after breast cancer treatment has no adverse affects on the prognosis of early and middle stage breast cancer patients. More study results are needed to normalize and detail the therapeutic regimen and fertility guidance.
authors.affiliation: Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiaotong Medical School, Shanghai 200092, China.
authors.forename: Yunshu
authors.initials: Y
authors.lastname: Lu
authors.forename: Kejin
authors.initials: K
authors.lastname: Wu
mesh_terms: D001943:Breast Neoplasms / Q000628:therapy*; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D011247:Pregnancy; D011379:Prognosis