title: ALK Gene Translocation in Inflammatory Myofibroblastic Tumor of the Urinary Bladder: A Case Report.
abstract: A 26-year-old woman with gross hematuria was seen in a previous hospital. Magnetic resonance imaging (MRI) showed a tumor at the dome of the urinary bladder with invasion outside of the bladder wall. The patient underwent transurethral resection of the bladder tumor (TUR-BT). From the result of the pathological examination, the tumor was suggested to be carcinosarcoma of the bladder. The patient was then referred to our hospital for treatment. We performed radical cystectomy and ileal conduit diversion. Pathological examination of the excised specimen revealed an inflammatory myofibroblastic tumor as the basis for immunostaining of anaplastic lymphoma kinase (ALK).
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Kimiaki
authors.initials: K
authors.lastname: Takagi
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Takai
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Kameyama
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Kengo
authors.initials: K
authors.lastname: Horie
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Mina
authors.initials: M
authors.lastname: Kikuchi
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Taku
authors.initials: T
authors.lastname: Kato
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Mizutani
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Kensaku
authors.initials: K
authors.lastname: Seike
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Tsuchiya
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Yasuda
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Shigeaki
authors.initials: S
authors.lastname: Yokoi
authors.affiliation: Pathology Division, Gifu University Hospital, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Natsuko
authors.initials: N
authors.lastname: Suzui
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakano
authors.affiliation: Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu city, Gifu 501-1194, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Deguchi
keywords: ALK; ALK, anaplastic lymphoma kinase; Bladder tumor; FISH; H&E, hematoxylin & eosin; IMT, inflammatory myofibroblastic tumor; Inflammatory myofibroblastic tumor; MRI, Magnetic resonance imaging; TUR-BT, transurethral resection of the bladder tumor