title: [A novel surgical mesh suitable for laparoscopy, studied on animal model].
abstract: BACKGROUND
  Reconstruction of the abdominal wall with mesh is a widely used surgical procedure. The non-absorbable meshes tend to cause numerous side-effects.
  
  
  OBJECTIVE
  The aim of the author was to produce an absorbable, polymer-based mesh that possesses appropriate chemical, mechanical and biological properties.
  
  
  METHODS
  A three-dimensional, biocompatible mesh was produced from poly-vinyl-alcohol using reactive electrospinning. Toxicity and cell-mesh interactions were tested using human lung carcinoma epithelial cells (A-549), and in vivo tests were conducted in 42 male Wistar rats at the 1-5, 7 and 14 postoperative days (3 rats/groups).
  
  
  RESULTS
  In the in vitro tests poly-vinyl-alcohol was biocompatible. In the in vivo tests no major complication was associated with the mesh made of poly-vinyl-alcohol.
  
  
  CONCLUSIONS
  The author concludes that this polymer mesh is biocompatible, it does not damage the surrounding tissues and integrates well with them.
authors.affiliation: Kísérletes és Sebészeti Műtéttani Intézet, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Nagyvárad tér 4., 1089.
authors.forename: Péter Marcell
authors.initials: PM
authors.lastname: Guba
mesh_terms: D034861:Abdominal Wall / Q000601:surgery*; D000818:Animals; D001672:Biocompatible Materials; D004195:Disease Models, Animal; D006801:Humans; D010535:Laparoscopy; D008297:Male; D011108:Polymers; D019736:Prostheses and Implants; D051381:Rats; D017208:Rats, Wistar; D013526:Surgical Mesh; D013718:Tensile Strength
chemical_list: D001672:Biocompatible Materials; D011108:Polymers
keywords: abdominal hernia; hasfali sérv; polivinil-alkohol; poly-vinyl-alcohol; sebészeti háló; surgical mesh