title: Pilomyxoid astrocytoma in the adult cerebellum.
abstract: Pilomyxoid astrocytoma (PMA) is a recently recognised World Health Organization (WHO) Grade II tumour that was previously characterised as a subtype of the WHO Grade I pilocytic astrocytoma (PA). PMA has a histological appearance distinct from PA and a poorer prognosis due to its greater propensity for local recurrence and cerebrospinal dissemination. Although originally considered a paediatric tumour involving mainly the hypothalamic and chiasmatic region, reports of the lesion occurring in the adult population and other areas of the neuroaxis are emerging. We review the literature on PMA within the adult population and present the first case of PMA in the cerebellum of an adult female.
authors.affiliation: Department of Neurosurgery, Royal Melbourne Hospital, 300 Grattan Street, Parkville, VIC 3050, Australia.
authors.forename: Annie S
authors.initials: AS
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, Royal Melbourne Hospital, 300 Grattan Street, Parkville, VIC 3050, Australia.
authors.forename: Iddo
authors.initials: I
authors.lastname: Paldor
authors.affiliation: Department of Anatomical Pathology, Royal Melbourne Hospital, VIC, Australia.
authors.forename: Alpha E
authors.initials: AE
authors.lastname: Tsui
authors.affiliation: Department of Neurosurgery, Royal Melbourne Hospital, 300 Grattan Street, Parkville, VIC 3050, Australia; Department of Surgery, Royal Melbourne Hospital, University of Melbourne, VIC, Australia. Electronic address: tanya.yuen@mh.org.au.
authors.forename: Tanya I
authors.initials: TI
authors.lastname: Yuen
mesh_terms: D001254:Astrocytoma / Q000473:pathology* / Q000601:surgery*; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000601:surgery*; D003388:Cranial Fossa, Posterior / Q000601:surgery; D003399:Craniotomy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local; D019635:Neurosurgical Procedures; D011379:Prognosis; D016896:Treatment Outcome; D055815:Young Adult
keywords: Adult; Cerebellum; Pilocytic astrocytoma; Pilomyxoid astrocytoma