title: Gender and Age Analyses of NIRS/STAI Pearson Correlation Coefficients at Resting State.
abstract: According to the valence asymmetry hypothesis, the left/right asymmetry of PFC activity is correlated with specific emotional responses to mental stress and personality traits. In a previous study we measured spontaneous oscillation of oxy-Hb concentrations in the bilateral PFC at rest in normal adults employing two-channel portable NIRS and computed the laterality index at rest (LIR). We investigated the Pearson correlation coefficient between the LIR and anxiety levels evaluated by the State-Trait Anxiety Inventory (STAI) test. We found that subjects with right-dominant activity at rest showed higher STAI scores, while those with left dominant oxy-Hb changes at rest showed lower STAI scores such that the Pearson correlation coefficient between LIR and STAI was positive. This study performed Bootstrap analysis on the data and showed the following statistics of the target correlation coefficient: mean=0.4925 and lower confidence limit=0.177 with confidence level 0.05. Using the KS-test, we demonstrated that the correlation did not depend on age, whereas it did depend on gender.
authors.affiliation: Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan. takashi@matsumoto.elec.waseda.ac.jp.
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.affiliation: Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fuchita
authors.affiliation: Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ichikawa
authors.affiliation: Department of Electrical Engineering and Bioscience, Waseda University, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fukuda
authors.affiliation: Department of Electrical and Electronics Engineering, NEWCAT Research Institute, College of Engineering, Nihon University, Koriyama, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Takemura
authors.affiliation: Department of Electrical and Electronics Engineering, NEWCAT Research Institute, College of Engineering, Nihon University, Koriyama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sakatani
mesh_terms: D000367:Age Factors; D000465:Algorithms; D001007:Anxiety / Q000378:metabolism*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D012737:Sex Factors; D019265:Spectroscopy, Near-Infrared
keywords: Bootstrap analysis; Kolmogorov-Smirnov test; NIRS; Pearson correlation coefficient; STAI