title: Cascade polycyclizations in natural product synthesis.
abstract: Cascade (domino) reactions have an unparalleled ability to generate molecular complexity from relatively simple starting materials; these transformations are particularly appealing when multiple rings are forged during this process. In this tutorial review, we cover recent highlights in cascade polycyclizations as applied to natural product synthesis, including pericyclic, heteroatom-mediated, cationic, metal-catalyzed, organocatalytic, and radical sequences.
authors.affiliation: Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK. edward.anderson@chem.ox.ac.uk.
authors.forename: R
authors.initials: R
authors.lastname: Ardkhean
authors.affiliation: Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK. edward.anderson@chem.ox.ac.uk.
authors.forename: D F J
authors.initials: DF
authors.lastname: Caputo
authors.affiliation: Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK. edward.anderson@chem.ox.ac.uk.
authors.forename: S M
authors.initials: SM
authors.lastname: Morrow
authors.affiliation: Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK. edward.anderson@chem.ox.ac.uk.
authors.forename: H
authors.initials: H
authors.lastname: Shi
authors.affiliation: Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK. edward.anderson@chem.ox.ac.uk.
authors.forename: Y
authors.initials: Y
authors.lastname: Xiong
authors.affiliation: Chemistry Research Laboratory, 12 Mansfield Road, Oxford, OX1 3TA, UK. edward.anderson@chem.ox.ac.uk.
authors.forename: E A
authors.initials: EA
authors.lastname: Anderson
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis*; D002384:Catalysis; D003500:Cyclization
chemical_list: D001688:Biological Products