title: Effects of vigorous walking exercise on core body temperature and inhibitory control in thermosensitive persons with multiple sclerosis.
abstract: OBJECTIVE
  Acute, moderate intensity aerobic exercise might improve cognition in multiple sclerosis (MS), but it is unknown if increases in core body temperature (Ctemp) that negates those effects in thermosensitive persons with MS.
  
  
  METHODS
  Fourteen fully ambulatory, thermosensitive persons with MS completed 20-min bouts of vigorous intensity treadmill walking exercise and seated quiet rest in a randomized, counterbalanced order. Ctemp was measured throughout each experimental condition. Inhibitory control (i.e., an executive function) was measured immediately prior to and following each condition.
  
  
  RESULTS
  Ctemp was elevated (~0.6 °C) with vigorous exercise versus quiet rest (p < 0.05). There further were pre-to-post improvements in inhibitory control for vigorous exercise versus quiet rest (ηp(2) = 0.29).
  
  
  CONCLUSIONS
  Exercise-related increases in Ctemp do not nullify the potential acute exercise benefits on inhibitory control in MS.
authors.affiliation: Department of Kinesiology & Community Health, University of Illinois at Urbana-Champaign, 906 S Goodwin Ave, Urbana, IL 61801, USA.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Sandroff
authors.affiliation: Department of Kinesiology & Community Health, University of Illinois at Urbana-Champaign, 906 S Goodwin Ave, Urbana, IL 61801, USA.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Motl
authors.affiliation: Department of Applied Physiology & Wellness, Southern Methodist University, PO Box 750382, Dallas, TX 75275-0455, USA.
authors.forename: Scott L
authors.initials: SL
authors.lastname: Davis
mesh_terms: D000328:Adult; D001831:Body Temperature; D056344:Executive Function / Q000502:physiology*; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology* / Q000523:psychology* / Q000534:rehabilitation; D016896:Treatment Outcome; D016138:Walking
keywords: body temperature; cognition; exercise; heat; multiple sclerosis; thermosensitivity