title: Pap Test Reporting Rates for Conventional Smear and Liquid-Based Cervical Cytology from the Largest Academic Women's Hospital in China: Analysis of 1,248,785 Pap Test Reports.
abstract: OBJECTIVE
  The Obstetrics and Gynecology Hospital of Fudan University (OGHFU) in Shanghai is the largest academic women's hospital in China. Between 2009 and 2014, the use of liquid-based cytology (LBC) significantly increased while gradually adopting the Bethesda System (TBS), and in 2012 local regulations mandated that pathologists replace technicians to sign out Pap tests.
  
  
  METHODS
  A retrospective OGHFU database search documented all Pap test reports between 2009 and 2014 by specimen type, either LBC or conventional Pap smears (CPS), and final reporting category. A total of 1,224,785 Pap reports were analyzed to document variations in Pap test reporting during a period of major change in cervical screening in China.
  
  
  RESULTS
  LBC gradually replaced CPS, which declined from over 65% of Pap tests in 2010 to 6.4% in 2014. Of 514,811 Pap reports using the traditional class system, class I (negative) reports accounted for 98.3% of results. With the introduction of TBS reporting, pathologist reviews and substantial replacement of CPS by LBC, the laboratory abnormal Pap test rate increased significantly to almost 5%.
  
  
  CONCLUSIONS
  Changes in cervical cytology reporting between 2009 and 2014 in China's largest academic women's hospital reflected both increased use of LBC and the introduction of pathologist TBS reporting. Abnormality rates increased significantly and fell within CAP benchmark ranges.
authors.affiliation: Department of Pathology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, PR China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Tao
authors.forename: R Marshall
authors.initials: RM
authors.lastname: Austin
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.forename: Lihong
authors.initials: L
authors.lastname: Zhang
authors.forename: Jianan
authors.initials: J
authors.lastname: Xiao
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Xianrong
authors.initials: X
authors.lastname: Zhou
authors.forename: Chengquan
authors.initials: C
authors.lastname: Zhao
mesh_terms: D000046:Academic Medical Centers / Q000592:standards / Q000639:trends*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019985:Benchmarking / Q000639:trends; D002681:China; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008875:Middle Aged; D065006:Papanicolaou Test / Q000592:standards / Q000639:trends*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014626:Vaginal Smears / Q000592:standards / Q000639:trends*; D055815:Young Adult