title: The GAAIN Entity Mapper: An Active-Learning System for Medical Data Mapping.
abstract: This work is focused on mapping biomedical datasets to a common representation, as an integral part of data harmonization for integrated biomedical data access and sharing. We present GEM, an intelligent software assistant for automated data mapping across different datasets or from a dataset to a common data model. The GEM system automates data mapping by providing precise suggestions for data element mappings. It leverages the detailed metadata about elements in associated dataset documentation such as data dictionaries that are typically available with biomedical datasets. It employs unsupervised text mining techniques to determine similarity between data elements and also employs machine-learning classifiers to identify element matches. It further provides an active-learning capability where the process of training the GEM system is optimized. Our experimental evaluations show that the GEM system provides highly accurate data mappings (over 90% accuracy) for real datasets of thousands of data elements each, in the Alzheimer's disease research domain. Further, the effort in training the system for new datasets is also optimized. We are currently employing the GEM system to map Alzheimer's disease datasets from around the globe into a common representation, as part of a global Alzheimer's disease integrated data sharing and analysis network called GAAIN. GEM achieves significantly higher data mapping accuracy for biomedical datasets compared to other state-of-the-art tools for database schema matching that have similar functionality. With the use of active-learning capabilities, the user effort in training the system is minimal.
authors.affiliation: Laboratory of Neuro Imaging, Keck School of Medicine, Stevens Neuroimaging and Informatics Institute, University of Southern California Los Angeles, CA, USA.
authors.forename: Naveen
authors.initials: N
authors.lastname: Ashish
authors.affiliation: Laboratory of Neuro Imaging, Keck School of Medicine, Stevens Neuroimaging and Informatics Institute, University of Southern California Los Angeles, CA, USA.
authors.forename: Peehoo
authors.initials: P
authors.lastname: Dewan
authors.affiliation: Laboratory of Neuro Imaging, Keck School of Medicine, Stevens Neuroimaging and Informatics Institute, University of Southern California Los Angeles, CA, USA.
authors.forename: Arthur W
authors.initials: AW
authors.lastname: Toga
keywords: active Learning; common data model; data harmonization; data mapping; machine learning