title: [A Case of Penetrating Diverticulum of the Small Intestine that Occurred during Chemotherapy for Esophageal Cancer].
abstract: An 80-year-old man was seen by his family doctor with chief complaints of fatigue and loss of appetite. Upper gastrointestinal endoscopy showed a type 2 tumor of the lower thoracic esophagus, and the patient was referred to our hospital. Squamous cell carcinoma was diagnosed on biopsy, and computed tomography (CT) showed multiple pulmonary metastases. The patient was diagnosed with Stage Ⅳ thoracic esophageal carcinoma, and was started on combined chemotherapy with 5-FU plus CDDP. Seven days after the start of chemotherapy, the patient developed mild intermittent pain. By day 18, the blood tests showed a marked inflammatory response, and a CT scan showed an abscess in the small bowel mesentery. We suspected an intra-abdominal abscess caused by small bowel perforation, and performed a partial resection of the small bowel and abscess drainage. Postoperatively, pathology tests revealed a diagnosis of a small intestinal diverticulum, which had penetrated the mesentery. We report our experience of a rare case of penetrating diverticulum of the small intestine that occurred during chemotherapy for esophageal cancer, and review the literature.
authors.affiliation: Dept. of Surgery, Osaka Rosai Hospital.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Yoshida
authors.forename: Ryohei
authors.initials: R
authors.lastname: Kawabata
authors.forename: Masato
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: Chizu
authors.initials: C
authors.lastname: Kameda
authors.forename: Chikato
authors.initials: C
authors.lastname: Koga
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakami
authors.forename: Toshiki
authors.initials: T
authors.lastname: Hitora
authors.forename: Masaki
authors.initials: M
authors.lastname: Hirota
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ikenaga
authors.forename: Junzo
authors.initials: J
authors.lastname: Shimizu
authors.forename: Hideaki
authors.initials: H
authors.lastname: Miwa
authors.forename: Junichi
authors.initials: J
authors.lastname: Hasegawa
mesh_terms: D018784:Abdominal Abscess / Q000175:diagnosis; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001706:Biopsy; D018288:Carcinoma, Small Cell / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D003937:Diagnosis, Differential; D004240:Diverticulum / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy*; D004322:Drainage; D004938:Esophageal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D007410:Intestinal Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy*; D007421:Intestine, Small / Q000473:pathology*; D008297:Male
chemical_list: D002945:Cisplatin; D005472:Fluorouracil