title: Evans syndrome and its link with systemic lupus erythematosus.
abstract: Evans syndrome is a rare syndrome associated with the presence of autoimmune hemolytic anemia and simultaneous or sequential development of thrombocytopenia. It was first described by Evan and Duane in 1951. It is one of the rare presenting features of autoimmune disorders, especially systemic lupus erythematosus (SLE), and sometimes may even precede the onset of disease. Primary Evans syndrome with no cause is very rare and is seen in children. Here, we describe a case of secondary Evans syndrome with severe hemolytic anemia leading to acute kidney injury and recovery thereafter only to develop lupus nephritis a few months later. This is one of the rare presentations of SLE and there are only anecdotal case reports.
authors.affiliation: Department of Nephrology, Armed Forces Medical College and Command Hospital, Southern Command, Pune, India.
authors.forename: Satish
authors.initials: S
authors.lastname: Mendonca
authors.forename: Sachin
authors.initials: S
authors.lastname: Srivastava
authors.forename: Rajan
authors.initials: R
authors.lastname: Kapoor
authors.forename: Devika
authors.initials: D
authors.lastname: Gupta
authors.forename: Pooja
authors.initials: P
authors.lastname: Gupta
authors.forename: M L
authors.initials: ML
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000209:etiology*; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis; D013921:Thrombocytopenia / Q000175:diagnosis / Q000209:etiology*