title: Assessing disease activity in psoriasis and psoriatic arthritis: impact on management and therapy.
abstract: The management of psoriatic arthritis (PsA) and psoriasis has undergone major advancements over the last decade. This has been made possible, in part, due to the introduction of new therapies for their management, as well as global collaboration in the development of outcome measures and "treat- to- target" paradigms. In this review article, we discuss how disease activity is measured and the outcome measures that have been recently developed for the management of PsA. The importance of assessing the individual domains as well as global assessments both from the physician and patient perspective, and the development of composite measures are discussed. The newer PsA specific measures are expected to be more commonly used in clinical trials as well as clinical practice.
authors.affiliation: a Department of Medicine, and Department of Laboratory Medicine and Pathobiology , University of Toronto , Toronto , Ontario , Canada.|b Institute of Medical Science , University of Toronto , Toronto , Ontario , Canada.|c Krembil Research Institute , University Health Network , Toronto , Ontario , Canada.
authors.forename: Vinod
authors.initials: V
authors.lastname: Chandran
authors.affiliation: d Department of Internal Medicine , Prince Mshiyeni Memorial Hospital, Nelson R Mandela School of Medicine, University of Kwazulu-Natal , Durban , South Africa.|e Department of Clinical Immunology and Rheumatology, Academic Medical Center , University of Amsterdam , Amsterdam , The Netherlands.
authors.forename: Ajesh B
authors.initials: AB
authors.lastname: Maharaj
mesh_terms: D015535:Arthritis, Psoriatic / Q000175:diagnosis* / Q000628:therapy*; D019468:Disease Management; D006801:Humans; D017063:Outcome Assessment, Health Care; D011565:Psoriasis / Q000175:diagnosis* / Q000628:therapy*; D012720:Severity of Illness Index
keywords: Composite disease activity measures; Spondyloarthritis; dactylitis; enthesitis; outcome measures