title: [Management of bleeding and infections in the context of visceral surgery].
abstract: Bleeding and vascular infections are serious potential complications during abdominal general surgery. The management of bleeding depends on the extent and localization and can range from the application of hemostatics to vascular sutures, interpositioning and ligatures. The use of prosthetic biomaterials implanted endoluminally or during open reconstruction permits palliation of potentially fatal conditions. The overall incidence of infections involving vascular prostheses is relatively low because of routine antibiotic prophylaxis prior to surgery, refinements in sterilization and packaging of devices and careful adherence to aseptic procedural and surgical techniques. When infections occur detection and definitive therapy of the vascular prosthesis are often delayed and the management is complex and tedious. Infections involving vascular prostheses are difficult to eradicate and in general, surgical therapy is required often coupled with excision of the prosthesis. Keys to success include accurate diagnostics to identify the organism and extent of graft infections, specific long-term antibiotic therapy and well-planned surgical interventions to excise and replace the infected graft and sterilize the local tissue. Regardless of the technique used to eradicate graft infections, success is measured by patient survival, freedom from recurrent infection and patency of revascularization. Even when treatment is successful, the morbidity associated with vascular graft infections is considerable. Aortoenteric fistulas (AEF) are a rare (incidence < 1.5 %) but often fatal complication. Primary diagnosis of AEF remains difficult. Computed tomography (CT) and fluorodeoxyglucose positron emission tomography CT (FDG-PET-CT) are the diagnostic tools of choice. Therapy consists of an urgent individualized interdisciplinary surgical approach with primary axillofemoral bypass and secondary prosthesis explantation or in situ replacement and subsequent bowel resection. Endovascular aortic repair (EVAR) is reserved for primary aortoenteric fistulas in patients with no signs of infection or in emergency cases as a bridging method.
authors.affiliation: Klinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland. dittmar.boeckler@med.uni-heidelberg.de.
authors.forename: D
authors.initials: D
authors.lastname: Böckler
authors.affiliation: Klinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Hyhlik-Dürr
authors.affiliation: Klinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Hakimi
authors.affiliation: Klinik für Anästhesie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Brenner
authors.affiliation: Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Ulrich
authors.affiliation: Klinik für Anästhesie, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Hofer
mesh_terms: D019072:Antibiotic Prophylaxis; D001018:Aortic Diseases / Q000000981:diagnostic imaging / Q000601:surgery; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D057510:Endovascular Procedures / Q000379:methods; D019788:Fluorodeoxyglucose F18; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000601:surgery*; D006488:Hemostasis, Surgical / Q000379:methods; D007412:Intestinal Fistula / Q000000981:diagnostic imaging / Q000601:surgery; D007431:Intraoperative Complications / Q000000981:diagnostic imaging / Q000601:surgery*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011379:Prognosis; D013530:Surgical Wound Infection / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016157:Vascular Fistula / Q000000981:diagnostic imaging / Q000601:surgery; D014656:Vascular Surgical Procedures / Q000379:methods; D014781:Viscera / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D019788:Fluorodeoxyglucose F18
keywords: Aortoenteric fistula; Artery; Complication; Surgery; Vein