title: AIF Is "Always In Fashion" for T Cells.
abstract: AIF has been known to have both apoptotic and metabolic roles. Green and colleagues show that T cells, but not B cells, rely on AIF to maintain mitochondrial electron transport and that metabolic, rather than apoptotic, pathways mediate this dependence.
authors.affiliation: Vanderbilt Center for Immunobiology, Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA.
authors.forename: Marc O
authors.initials: MO
authors.lastname: Johnson
authors.affiliation: Vanderbilt Center for Immunobiology, Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address: jeff.rathmell@vanderbilt.edu.
authors.forename: Jeffrey C
authors.initials: JC
authors.lastname: Rathmell
mesh_terms: D000818:Animals; D051033:Apoptosis Inducing Factor / Q000378:metabolism*; D001402:B-Lymphocytes / Q000378:metabolism*; D008928:Mitochondria / Q000502:physiology*; D013601:T-Lymphocytes / Q000378:metabolism*
chemical_list: D051033:Apoptosis Inducing Factor