title: Painful Ejaculation with Cyclobenzaprine: A Case Report and Literature Review.
abstract: BACKGROUND
  Sexual dysfunction is a well-known side effect of antidepressants. Painful ejaculation is a rare side effect that has been reported with the use of some psychiatric drugs such as triclyclic antidepressants. Cyclobenzaprine is a muscle relaxant that is structurally similar to tricyclic antidepressants. It is the most commonly prescribed muscle relaxant in the United States and accounts for 18% of all prescriptions written for chronic back pain.
  
  
  METHODS
  A 55-year-old man was referred to our pain medicine clinic for evaluation and treatment of pain with ejaculation.
  
  
  METHODS
  The main outcome measure was to review the current published literature and case reports on painful ejaculation from medication use, in particular tricyclic antidepressants.
  
  
  RESULTS
  After discontinuation of cyclobenzaprine, our patient's sexual dysfunction resolved. This result was consistent with the literature reviewed on the topic.
  
  
  CONCLUSIONS
  Painful ejaculation is likely an underreported side effect of tricyclic antidepressants and cyclobenzaprine use. Fortunately, these symptoms are reversible and discontinuation of these medications is typically an effective cure. K raus MB , W ie CS , G orlin AW , W isenbaugh ES , and R osenfeld DM . Painful ejaculation with cyclobenzaprine: A case report and literature review. S ex M ed 2015;3:343-345.
authors.affiliation: Department of Anesthesiology Mayo Clinic Phoenix AZ USA.
authors.forename: Molly B
authors.initials: MB
authors.lastname: Kraus
authors.affiliation: Department of Anesthesiology Mayo Clinic Phoenix AZ USA.
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Wie
authors.affiliation: Department of Anesthesiology Mayo Clinic Phoenix AZ USA.
authors.forename: Andrew W
authors.initials: AW
authors.lastname: Gorlin
authors.affiliation: Department of Urology Mayo Clinic Phoenix AZ USA.
authors.forename: Eric S
authors.initials: ES
authors.lastname: Wisenbaugh
authors.affiliation: Department of Anesthesiology Mayo Clinic Phoenix AZ USA.
authors.forename: David M
authors.initials: DM
authors.lastname: Rosenfeld
keywords: Cyclobenzaprine; Ejaculation; Orgasmic Disorder; Sexual Dysfunction