title: [Three Cases of Stage Ⅳ Low Rectal Cancer with Lateral Pelvic Lymph Node Metastasis].
abstract: Case 1: A 61-year-old man who had a diagnosis of low rectal cancer with lateral pelvic lymph node (LPLN) metastasis and multiple liver metastases underwent low anterior resection with LPLN dissection. The initial surgery was followed by chemotherapy, and then an extended right hepatectomy with partial resection of the liver was performed. Subsequently, a lung metastasis was detected, and the lung was partially resected. The patient was alive 9 years and 6 months after the initial operation. Case 2: A 53-year-old man had a diagnosis of low rectal cancer. After 5 courses of mFOLFOX6 plus bevacizumab, he underwent low anterior resection with LPLN dissection and resection of the peritoneal metastasis. The patient was alive 6 years and 3 months after the surgery without any signs of recurrence. Case 3: A 48-year-old man had a diagnosis of low rectal cancer and multiple liver metastases. He underwent low anterior resection with LPLN dissection and right hepatic lobectomy. He subsequently showed liver and lung metastases. The patient received systemic chemotherapy, and is alive with recurrent disease. We report 3 cases of Stage Ⅳ low rectal cancer with LPLN metastasis, and propose that LPLN dissection is important as a part of R0 resection for Stage Ⅳ low rectal cancer.
authors.affiliation: Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tamura
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Shimada
authors.forename: Ryoma
authors.initials: R
authors.lastname: Yagi
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Tajima
authors.forename: Takuma
authors.initials: T
authors.lastname: Okamura
authors.forename: Masato
authors.initials: M
authors.lastname: Nakano
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Jun
authors.initials: J
authors.lastname: Sakata
authors.forename: Takashi
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kameyama
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Kosugi
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Wakai
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Nogami
authors.forename: Satoshi
authors.initials: S
authors.lastname: Maruyama
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Takii
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010388:Pelvis / Q000473:pathology* / Q000601:surgery; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D012008:Recurrence; D014057:Tomography, X-Ray Computed