title: [A Case of Gastric Cancer Associated with Sjögren's Syndrome and Interstitial Pneumonia].
abstract: A 77-year-old man presented with poor appetite and dyspnea. A gastroendoscopy showed an advanced gastric cancer and a CT scan demonstrated diffuse interstitial infiltrative shadows in both lungs. Laboratory data showed high level of anti-SSA and anti-SSB antibodies, suggestive of interstitial pneumonia associated with Sjögren's syndrome. Although the levels of KL-6 and SP-D, markers of interstitial pneumonia, decreased after steroid and immunosuppressive therapy, the CT findings of interstitial pneumonia showed no remarkable change. Surgery was performed 2 months after the administration of prednisolone since the respiratory function had improved, allowing the administration of general anesthesia. A CT scan revealed remarkable improvement of the lung lesions after the surgery. Therefore, it is likely that Sjögren's syndrome and interstitial pneumonia manifested as paraneoplastic syndromes in the presented case.
authors.affiliation: Dept. of Gastroenterological Surgery, Aichi Medical University Hospital.
authors.forename: Mirai
authors.initials: M
authors.lastname: Ido
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Mishima
authors.forename: Kengo
authors.initials: K
authors.lastname: Kimura
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Iwata
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Kiyota
authors.forename: Kenichi
authors.initials: K
authors.lastname: Komaya
authors.forename: Takuya
authors.initials: T
authors.lastname: Saito
authors.forename: Norifumi
authors.initials: N
authors.lastname: Ohashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Arikawa
authors.forename: Seiji
authors.initials: S
authors.lastname: Ishiguro
authors.forename: Shunichiro
authors.initials: S
authors.lastname: Komatsu
authors.forename: Masahiko
authors.initials: M
authors.lastname: Miyachi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Sano
mesh_terms: D000368:Aged; D005743:Gastrectomy; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications*; D008297:Male; D011379:Prognosis; D012859:Sjogren's Syndrome / Q000150:complications*; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery