title: Noonan Syndrome Complicated by Primary Pulmonary Lymphangiectasia.
abstract: Noonan syndrome is a genetic disorder that has several features common to other conditions, making diagnosis a challenge. This column summarizes the case of a neonate with an atypical presentation of Noonan syndrome involving a fatal type of lymphangiectasia resulting in persistent pleural effusions. Radiographic features of this condition are presented along with the complexities of diagnosis and treatment.
authors.forename: Jaclyn Jo
authors.initials: JJ
authors.lastname: Ford
authors.forename: Carol W
authors.initials: CW
authors.lastname: Trotter
mesh_terms: D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007231:Infant, Newborn; D008171:Lung Diseases / Q000150:complications / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology; D008200:Lymphangiectasis / Q000150:complications / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology; D008220:Lymphography / Q000379:methods; D008297:Male; D009634:Noonan Syndrome / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D010996:Pleural Effusion / Q000000981:diagnostic imaging*; D012121:Respiration, Artificial / Q000379:methods*; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology / Q000628:therapy; D000069258:Thoracentesis / Q000379:methods