title: A comparison between plasmapheresis and intravenous immunoglobulin in children with Guillain-Barré syndrome in Upper Egypt.
abstract: OBJECTIVE
  The aim of our study is to assess the clinico-electrophysiological proﬁle of children with Guillain-Barré syndrome (GBS) in Upper Egypt and to compare the efficacy of plasmapheresis versus other treatment modalities.
  
  
  METHODS
  This was a retrospective study of children from January 2010 to October 2014 diagnosed as GBS. It included 62 cases.
  
  
  RESULTS
  Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) was the most prevalent type of GBS in our locality. As regards the treatment, 32 cases received plasmapheresis while 30 patients received intravenous immunoglobulin. We found a significant decrease in the duration of hospitalization and a significant increase in the number of children with complete recovery in cases treated with plasmapheresis.
  
  
  CONCLUSIONS
  GBS is not uncommon in children of Upper Egypt, with AIDP the most prevalent type. Plasmapheresis is the best treatment modalities for GBS as it reduces the duration of hospital stay and hastens the recovery of those children.
authors.affiliation: Associate Professor of Pediatrics, Faculty of Medicine, University of Assiut, Assiut 71516, Egypt.
authors.forename: Khaled
authors.initials: K
authors.lastname: Saad
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
authors.forename: Ismail L
authors.initials: IL
authors.lastname: Mohamad
authors.affiliation: Department of Neurology, Faculty of Medicine, Assiut University, Assiut, Egypt.
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Abd El-Hamed
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
authors.forename: Mostafa S K
authors.initials: MS
authors.lastname: Tawfeek
authors.affiliation: Department of Pediatrics, Qena Faculty of Medicine, South Valley University, Egypt.
authors.forename: Ahmed E
authors.initials: AE
authors.lastname: Ahmed
authors.affiliation: Department of Pediatrics, Qena Faculty of Medicine, South Valley University, Egypt.
authors.forename: Khaled A
authors.initials: KA
authors.lastname: Abdel Baseer
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
authors.forename: Ahmed S
authors.initials: AS
authors.lastname: El-Shemy
authors.affiliation: Department of Community Health Nursing, Assiut University, Assiut, Egypt.
authors.forename: Amira A
authors.initials: AA
authors.lastname: El-Houfey
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt.
authors.forename: Diaa M
authors.initials: DM
authors.lastname: Tamer
keywords: Guillain–Barré Syndrome; children; intravenous immunoglobulin; outcome; plasmapheresis