title: Sofosbuvir + amiodarone: bradycardia and conduction disturbances.
abstract: Cardiac disorders caused by sofosbuvir are liable to be worsened by concomitant use of one of the many drugs that provoke cardiac arrhythmia.
mesh_terms: D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D000998:Antiviral Agents / Q000009:adverse effects*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D001919:Bradycardia / Q000139:chemically induced*; D053840:Brugada Syndrome; D000075224:Cardiac Conduction System Disease; D004347:Drug Interactions; D006329:Heart Conduction System / Q000002:abnormalities*; D006801:Humans; D000069474:Sofosbuvir / Q000009:adverse effects*
chemical_list: D000889:Anti-Arrhythmia Agents; D000998:Antiviral Agents; D000638:Amiodarone; D000069474:Sofosbuvir