title: Insulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia.
abstract: Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affect how such patients are managed with insulin.
authors.affiliation: Department of Diabetes King's College NHS Trust London UK.
authors.forename: Martin
authors.initials: M
authors.lastname: Whyte
authors.affiliation: Department of Pathology King's College NHS Trust London UK.
authors.forename: Alberto
authors.initials: A
authors.lastname: Quaglia
authors.affiliation: Department of Diabetes King's College NHS Trust London UK.
authors.forename: David
authors.initials: D
authors.lastname: Hopkins
keywords: NAFLD; detemir; hepatoselective; hypertriglyceridaemia