title: Use of the Sequential Organ Failure Assessment score for evaluating outcome among obstetric patients admitted to the intensive care unit.
abstract: OBJECTIVE
  To evaluate the prognostic value of the Sequential Organ Failure Assessment (SOFA) score among obstetric patients admitted to the intensive care unit (ICU).
  
  
  METHODS
  A prospective study was conducted among 90 consecutive obstetric patients who were admitted to the ICU of Guru Teg Bahadur Hospital, Delhi, India, between October 6, 2010, and December 25, 2011. Maximum SOFA score was calculated for each of the six organ systems. Receiver operating characteristic curves were used to determine critical cutoff values for total, maximum total, and mean total SOFA scores at various time points.
  
  
  RESULTS
  Total SOFA score at admission displayed an area under the curve (AUC) of 0.949, a cutoff value of at least 8.5, sensitivity of 86.7%, and specificity of 90.0%. Maximum total SOFA score had an AUC of 0.980, a cutoff value of at least 10.0, sensitivity of 96.7%, and specificity of 90.0%. Mean total SOFA score had an AUC of 0.997, a cutoff value of at least 9.0, sensitivity of 96.7%, and specificity of 96.7%.
  
  
  CONCLUSIONS
  In terms of discriminatory power for predicting mortality among obstetric patients admitted to the ICU, total SOFA score at admission was the most relevant, simple, and accurate measure.
authors.affiliation: Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. Electronic address: drjainshruti@gmail.com.
authors.forename: Shruti
authors.initials: S
authors.lastname: Jain
authors.affiliation: Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Kiran
authors.initials: K
authors.lastname: Guleria
authors.affiliation: Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Amita
authors.initials: A
authors.lastname: Suneja
authors.affiliation: Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Neelam B
authors.initials: NB
authors.lastname: Vaid
authors.affiliation: Department of Anaesthesiology and Critical Care, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Sharmila
authors.initials: S
authors.lastname: Ahuja
mesh_terms: D000328:Adult; D019540:Area Under Curve; D016638:Critical Illness / Q000401:mortality* / Q000628:therapy; D005260:Female; D006760:Hospitalization; D006801:Humans; D007194:India; D007362:Intensive Care Units; D009017:Morbidity; D000067491:Near Miss, Healthcare / Q000706:statistics & numerical data*; D063305:Organ Dysfunction Scores; D017063:Outcome Assessment, Health Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D011295:Prenatal Care; D011446:Prospective Studies; D012372:ROC Curve; D012680:Sensitivity and Specificity; D012923:Social Class; D016896:Treatment Outcome
keywords: Critical illness; Intensive care unit; Near-miss cases; Obstetric cases; Prognostic score; Sequential Organ Failure Assessment score; Severe maternal morbidity