title: Negative pressure wound therapy for initial management of giant omphalocele.
abstract: BACKGROUND
  Current treatment of giant omphalocele includes "paint and wait" or placement of mesh or silo. These methods are associated with high complication rates. We propose negative pressure wound therapy as an alternative.
  
  
  METHODS
  Patients born between 2009 and 2014 with giant omphalocele were included. Outcomes analyzed were duration of therapy, time to full enteral feeds, treatment related complications, wound surface area over time, type, and time to definitive closure.
  
  
  RESULTS
  Eight patients were reviewed. The median duration of therapy was 68 days. Median time to full enteral feeds was 19 days. There were no treatment discontinuations or complications including sac ruptures, wound infections, or fistulas. Wound contraction stopped at 2 months or around 7 cm(2). All surviving patients underwent definitive closure.
  
  
  CONCLUSIONS
  Negative pressure wound therapy is a safe and effective treatment for giant omphalocele that allows feeding, has a low complication rate, and is completed in 2 months.
authors.affiliation: Department of Pediatric Surgery, Peyton Manning Children's Hospital, 2001 W 86th St., Indianapolis, IN, 46260, USA.
authors.forename: Beau
authors.initials: B
authors.lastname: Aldridge
authors.affiliation: Department of Surgery, School of Medicine, Indiana University, Riley Hospital for Children, Indianapolis, IN, USA.
authors.forename: Alan P
authors.initials: AP
authors.lastname: Ladd
authors.affiliation: Department of Pediatric Surgery, Peyton Manning Children's Hospital, 2001 W 86th St., Indianapolis, IN, 46260, USA.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Kepple
authors.affiliation: Department of Pediatric Surgery, Peyton Manning Children's Hospital, 2001 W 86th St., Indianapolis, IN, 46260, USA.
authors.forename: Teresa
authors.initials: T
authors.lastname: Wingle
authors.affiliation: Department of Pediatric Surgery, Peyton Manning Children's Hospital, 2001 W 86th St., Indianapolis, IN, 46260, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Ring
authors.affiliation: Department of Pediatric Surgery, Peyton Manning Children's Hospital, 2001 W 86th St., Indianapolis, IN, 46260, USA. Electronic address: erkokosk@stvincent.org.
authors.forename: Evan R
authors.initials: ER
authors.lastname: Kokoska
mesh_terms: D004750:Enteral Nutrition; D005260:Female; D006554:Hernia, Umbilical / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D054843:Negative-Pressure Wound Therapy; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology*
keywords: Negative pressure wound therapy; Omphalocele; Wound VAC