title: [Complete Response to Chemotherapy after Resection of Rectal Cancer with Virchow's Lymph Node Metastasis].
abstract: A 62-year-old woman was admitted to our hospital because of bloody stool. Colonoscopy revealed stenosis by a type 2 tumor of the recto-sigmoid colon. A biopsy specimen contained moderately differentiated adenocarcinoma. Thoraco-abdominal computed tomography (CT) showed liver metastasis (S7, 10 mm) and enlargement of Virchow's lymph node (17 mm) and several para-aortic lymph nodes (15 mm on average). Because of oozing from the tumor and severe stenosis of the recto-sigmoid colon, we performed laparoscopic-assisted high anterior resection of the primary lesion. After surgery, 3 courses of mFOLFOX6, 20 courses of mFOLFOX6 plus bevacizumab, and 5 courses of infusional 5-FU plus Leucovorin plus bevacizumab were administered. Thoraco-abdominal CT demonstrated complete response to the 1 year 2 months of chemotherapy. The patient has been alive without relapse for 2 years after surgery.
authors.affiliation: Dept. of Surgery, Kashiwara Municipal Hospital.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kuroda
authors.forename: Bunzo
authors.initials: B
authors.lastname: Nakata
authors.forename: Shigetomi
authors.initials: S
authors.lastname: Nakao
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Lee
authors.forename: Masashige
authors.initials: M
authors.lastname: Tendo
authors.forename: Takeshi
authors.initials: T
authors.lastname: Hori
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yokomatsu
authors.forename: Kosei
authors.initials: K
authors.lastname: Hirakawa
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Ishikawa
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome