title: Right middle lobe atelectasis in children with asthma and prognostic factors.
abstract: BACKGROUND
  Although right middle lobe (RML)-atelectasis of the lungs is a common complication of asthma, the relevant data is limited. The aim of this study is to define the characteristics of RML atelectasis in asthma during childhood.
  
  
  METHODS
  Children with asthma who had recently developed RML atelectasis were included; anti-inflammatory medications, clarithromycin, and inhaled salbutamol were prescribed, chest-physiotherapy (starting on the sixth day) was applied. Patients were reevaluated on the sixth, fourteenth, thirtieth, and ninetieth days, chest X-rays were taken if the atelectasis had not resolved at the time of the previous visit.
  
  
  RESULTS
  Twenty-seven patients (6.8 (4.8-8.3) years, 48.1% male) with RML atelectasis were included. Symptoms started 15 (7-30) days before admission. The thickness of the atelectasis was 11.8 ± 5.8 mm; FEV1% was 75.9 ± 14.2 and Childhood Asthma Control Test scores were 11.8 ± 5.6 at the time of admission. The atelectasis had been resolved by the sixth (n = 3), fourteenth (n = 9), thirtieth (n = 10), and ninetieth days (n = 3). The treatment response of the patients whose atelectasis resolved in fourteen days was better on the sixth-day (atelectasis thickness: 4.7 ± 1.7 vs. 11.9 ± 7.3 mm, p = 0.021) compared to those whose atelectasis resolved later. Nearly half (54.5%) of the patients whose atelectasis had resolved by fourteen days were using controller medications at the time of admission. However, only two patients (13.3%) were on controller treatment in the latter group (p = 0.032). Regression analysis didn't reveal any prognostic factors for the early resolution of atelectasis.
  
  
  CONCLUSIONS
  Early diagnosis and treatment of RML atelectasis prevents complications. Patients who had early resolution of atelectasis had already been on anti-inflammatory medications, and responded better to aggressive treatment within the first week.
authors.affiliation: Department of Pediatric Allergy, Faculty of Medicine, Hacettepe University, Ankara 06100, Turkey. Electronic address: ozgeusoyer@gmail.com.
authors.forename: Ozge
authors.initials: O
authors.lastname: Soyer
authors.affiliation: Department of Pediatrics, Ministry of Health Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Cinar
authors.initials: C
authors.lastname: Ozen
authors.affiliation: Department of Pediatric Allergy, Faculty of Medicine, Hacettepe University, Ankara 06100, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Cavkaytar
authors.affiliation: Department of Radiology, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
authors.forename: Cagri
authors.initials: C
authors.lastname: Senyücel
authors.affiliation: Department of Pediatrics, Ministry of Health Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Yildiz
authors.initials: Y
authors.lastname: Dallar
mesh_terms: D001249:Asthma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D007958:Leukocyte Count; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D001261:Pulmonary Atelectasis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D013902:Radiography, Thoracic; D012129:Respiratory Function Tests; D012307:Risk Factors
chemical_list: D007073:Immunoglobulin E
keywords: Asthma control; Atelectasis; Complication; Pediatrics; Prevention