title: Neural systems implicated in obesity as an addictive disorder: from biological to behavioral mechanisms.
abstract: Contributing factors to obesity have been identified, yet prevention and treatment efforts have had limited long-term success. It has recently been suggested that some individuals may experience an addictive-like response to certain foods, such as losing control over consumption and continued consumption despite negative consequences. In support, shared biological and behavioral features seem to exist between "food addiction" and traditional substance-use disorders. "Food addiction" may be another important contributor to obesity. The current chapter reviews existing literature regarding neural systems implicated similarly in obesity and addiction, discusses unique considerations for addictive-like eating, and proposes directions for future research regarding "food addiction" as an emerging construct for addiction medicine.
authors.affiliation: Department of Psychology, University of Michigan, Ann Arbor, MI, USA.
authors.forename: Erica M
authors.initials: EM
authors.lastname: Schulte
authors.affiliation: Oregon Research Institute, Eugene, OR, USA.
authors.forename: Sonja
authors.initials: S
authors.lastname: Yokum
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Department of Neurobiology, Child Study Center, Yale University School of Medicine, New Haven, CT, USA; CASAColumbia, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: Marc N
authors.initials: MN
authors.lastname: Potenza
authors.affiliation: Department of Psychology, University of Michigan, Ann Arbor, MI, USA. Electronic address: agearhar@umich.edu.
authors.forename: Ashley N
authors.initials: AN
authors.lastname: Gearhardt
mesh_terms: D000818:Animals; D016739:Behavior, Addictive / Q000150:complications / Q000503:physiopathology*; D005247:Feeding Behavior / Q000502:physiology* / Q000523:psychology; D005502:Food; D006801:Humans; D009765:Obesity / Q000150:complications / Q000503:physiopathology*; D012201:Reward; D019966:Substance-Related Disorders / Q000503:physiopathology* / Q000523:psychology
keywords: Addiction; Food addiction; Obesity; Reward; Substance dependence