title: Diabetes, Dementia and Hypoglycemia.
abstract: We are experiencing an epidemic of both diabetes and dementia among older adults in this country. The risk for dementia appears to be increased in patients with diabetes, and patients with dementia and diabetes appear to be at greater risk for severe hypoglycemia. In addition, there may be an increased risk for developing dementia by older patients with diabetes who have had episodes of severe hypoglycemia, although this issue is controversial. In this article, we review the factors that contribute to the increased risk for dementia in older adults with diabetes and outline the complex relationships between hypoglycemia and dementia.
authors.affiliation: Department of Medicine, Vancouver Hospital and the University of British Columbia, Vancouver, British Columbia, Canada; Geriatric Division, Centre Intégré Universitaire de Soins et Services en Santé de L'Estrie (CIUSSS)-CHUS, Sherbrooke, Québec, Canada. Electronic address: meneilly@mail.ubc.ca.
authors.forename: Graydon S
authors.initials: GS
authors.lastname: Meneilly
authors.affiliation: Department of Medicine, Vancouver Hospital and the University of British Columbia, Vancouver, British Columbia, Canada; Geriatric Division, Centre Intégré Universitaire de Soins et Services en Santé de L'Estrie (CIUSSS)-CHUS, Sherbrooke, Québec, Canada.
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Tessier
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D002170:Canada / Q000453:epidemiology; D003131:Combined Modality Therapy / Q000009:adverse effects; D003704:Dementia / Q000453:epidemiology / Q000517:prevention & control*; D015140:Dementia, Vascular / Q000453:epidemiology / Q000517:prevention & control; D003920:Diabetes Mellitus / Q000097:blood / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D003925:Diabetic Angiopathies / Q000453:epidemiology / Q000517:prevention & control; D003929:Diabetic Neuropathies / Q000453:epidemiology / Q000517:prevention & control*; D003927:Diet, Diabetic; D019456:Health Transition; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced / Q000453:epidemiology / Q000517:prevention & control*; D007004:Hypoglycemic Agents / Q000009:adverse effects / Q000627:therapeutic use; D015994:Incidence; D009043:Motor Activity; D011236:Prediabetic State / Q000097:blood / Q000188:drug therapy / Q000523:psychology / Q000628:therapy; D015995:Prevalence; D012307:Risk Factors
chemical_list: D007004:Hypoglycemic Agents
keywords: Alzheimer disease; dementia; diabetes; diabète; démence; elderly; hypoglycemia; hypoglycémie; maladie d'Alzheimer; personnes âgées