title: [Advancement in the treatment against prostate cancer].
abstract: With the advancement of basic science and medical technology, the treatment against prostate cancer (PC) has dramatically changed. Although the introduction of robotic radical prostatectomy and particle therapies in patients with early stage PC is of much note, the issues on the over-treatment and treatment cost should be heeded. From these points, active surveillance has been an important strategy in these patients. In patients with metastatic hormone-sensitive PC, especially high volume metastases, androgen deprivation therapy (ADT) with docetaxel has been reported to prolong overall survival compared with ADT alone. Lastly, several novel therapeutic agents have been investigated and shown to be favorable outcomes in patients with castration resistant PC. This review focuses on the recent advancement in the treatment against PCs.
authors.forename: Nobuo
authors.initials: N
authors.lastname: Shinohara
authors.forename: Takashige
authors.initials: T
authors.lastname: Abe
authors.forename: Satoru
authors.initials: S
authors.lastname: Maruyama
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D020249:Hormone Replacement Therapy; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000628:therapy*
chemical_list: D018931:Antineoplastic Agents, Hormonal