title: Diastereo- and enantioselective construction of an indole-based 2,3-dihydrobenzofuran scaffold via catalytic asymmetric [3+2] cyclizations of quinone monoimides with 3-vinylindoles.
abstract: The first catalytic asymmetric [3+2] cyclization of quinone monoimides with olefins has been established, which employed 3-vinylindoles as a class of competent olefins and spiro-chiral phosphoric acid as a powerful chiral catalyst, leading to chemo-, diastereo- and enantioselective construction of a biologically important 2,3-dihydrobenzofuran framework with optical purity (up to 99% yield, >95 : 5 dr, 96 : 4 er).
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Xiao-Xue
authors.initials: XX
authors.lastname: Sun
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Hong-Hao
authors.initials: HH
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Guo-Hao
authors.initials: GH
authors.lastname: Li
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Li
authors.initials: L
authors.lastname: Meng
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn.
authors.forename: Feng
authors.initials: F
authors.lastname: Shi