title: Long-term results after laparoscopic sleeve gastrectomy in a large monocentric series.
abstract: BACKGROUND
  Laparoscopic sleeve gastrectomy (SG) has gained great popularity as a stand-alone bariatric procedure because short- and mid-term outcomes in terms of weight loss and resolution of co-morbidities have been very positive. However, long-term results from large series still are sparse.
  
  
  OBJECTIVE
  To evaluate the long-term clinical outcomes of SG in a large series of patients undergoing SG as a stand-alone procedure.
  
  
  METHODS
  University hospital in Italy.
  
  
  METHODS
  A retrospective analysis of prospectively collected data from 182 patients undergoing SG between 2006 and 2008 in the authors' institution. Long-term outcomes at 6 and 7 years were analyzed in terms of weight loss and co-morbidities resolution.
  
  
  RESULTS
  Mean initial body mass index (BMI) was 45.9±7.3 kg/m(2). Major postoperative complications occurred in 8 patients (5.4%): 4 leaks, 2 bleeding, 1 abdominal collection, and 1 dysphagia. All complications were managed conservatively. One hundred forty-eight patients (81.4%) completed the 72-month (6-year) follow-up. Thirty-seven patients (25%) reached a follow-up of 84 months. At year 6 follow-up the mean BMI and the mean percentage of excess weight loss (%EWL) were 30.2 kg/m(2) and 67.3%, respectively. Mean total body weight loss was 44.9 kg, while a %EWL >50 was registered in 123 patients (83.1%). Preoperative BMI did not significantly influence postoperative %EWL. Remission of type 2 diabetes mellitus, arterial hypertension, obstructive sleep apnea syndrome, and gastroesophageal reflux disease symptoms occurred in 83.8%, 59.7%, 75.6%, and 64.7% of patients, respectively.
  
  
  CONCLUSIONS
  %EWL and resolution of co-morbidities appear to be sustained 6 and 7 years after SG. Preoperative BMI is not predictive for weight loss outcomes.
authors.affiliation: Department of Surgical Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Casella
authors.affiliation: Department of Surgical Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. Electronic address: lelesori@hotmail.com.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Soricelli
authors.affiliation: Department of Surgical Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Giannotti
authors.affiliation: Department of Surgical Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Collalti
authors.affiliation: Department of Surgical Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Maselli
authors.affiliation: Department of Surgical Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Genco
authors.affiliation: Department of Surgical Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
authors.forename: Adriano
authors.initials: A
authors.lastname: Redler
authors.affiliation: Department of Surgical Sciences, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Basso
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000601:surgery; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000601:surgery; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D009767:Obesity, Morbid / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D011300:Preoperative Care; D011446:Prospective Studies; D012189:Retrospective Studies; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D016896:Treatment Outcome; D015431:Weight Loss / Q000502:physiology
keywords: Long-term results; Sleeve gastrectomy; Weight loss