title: [Value of Glasgow prognostic score in patients with adenocarcinoma of esophagogastric junction].
abstract: OBJECTIVE
  To evaluate the prognosis and predictive values of preoperative Glasgow prognostic score (GPS) for adenocarcinoma of esophagogastric junction(AEG) patients.
  
  
  METHODS
  A retrospective study of 322 AEG patients who received operation between January 2007 and March 2010 in Henan Provincial People's Hospital was performed. Clinical data, pathological characteristics, laboratory parameters and survival data were collected. The GPS was calculated based on C-reactive protein(CRP) and serum albumin(ALB) levels. Univariate and multivariate analysis were used to evaluate the prognostic value of GPS.
  
  
  RESULTS
  Among 322 patients, 0, 1, 2 of GPS were 192, 104 and 26 patients respectively. The median follow-up was 37 (4-73) months. In Kaplan-Meier analysis, median diseases-free survival (DFS) of GPS 0, 1, 2 was 47.0 (95% CI: 31.6-62.4), 15.0 (95% CI: 11.8-8.2) and 4.7 (95% CI: 3.8-5.6) months (P<0.01), and median overall survival (OS) was out of reach, 20.6 (95% CI: 15.8-25.4) and 7.0 (95% CI: 5.8-8.2) months (P<0.01). Univariate and multivariate analysis revealed that GPS was an independent predictor of DFS (P<0.01) and OS (P<0.01) of AEG.
  
  
  CONCLUSIONS
  GPS is an effective predictor of survival in AEG.
authors.affiliation: Department of Oncology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Cui
authors.affiliation: Department of Gastrointestinal Surgery, Henan Provincial Cancer Hospital, Zhengzhou University, Zhengzhou 450008, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Oncology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Mingyue
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department of Oncology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Zuxuan
authors.initials: Z
authors.lastname: Shi
authors.affiliation: Department of Oncology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Yaru
authors.initials: Y
authors.lastname: Fu
authors.affiliation: Department of Oncology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou 450003, China.
authors.forename: Lihong
authors.initials: L
authors.lastname: Cai
authors.affiliation: Department of Oncology, Henan Provincial People's Hospital, Zhengzhou University, Zhengzhou 450003, China. zhongliuerbingqu@163.com.
authors.forename: Tianhui
authors.initials: T
authors.lastname: Gao
mesh_terms: D000230:Adenocarcinoma; D002097:C-Reactive Protein; D018572:Disease-Free Survival; D004938:Esophageal Neoplasms; D004943:Esophagogastric Junction; D006801:Humans; D053208:Kaplan-Meier Estimate; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms
chemical_list: D002097:C-Reactive Protein