title: Cloacal dysgenesis sequence with bilateral renal agenesis and normal pulmonary development in twin pregnancy.
abstract: Cloacal dysgenesis sequence (CDS) is a rare congenital anomaly. It is characterised by a smooth perineum with absence of anal and genitourinary orifices, with reported incidence of 1:50,000-250,000 births. Association with bilateral renal agenesis is still rarer and resultant severe oligohydramnios is associated with pulmonary hypoplasia. Only a few cases of CDS with bilateral renal agenesis have been reported in the English language literature, with associated pulmonary hypoplasia as a default phenomenon. We report a case of CDS and bilateral renal agenesis without associated pulmonary hypoplasia in a twin pregnancy, which, to the best of our knowledge, is the second reported case of this amalgamation.
authors.affiliation: Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Sundram
authors.initials: S
authors.lastname: Jegadeesh
authors.affiliation: Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Jai Kumar
authors.initials: JK
authors.lastname: Mahajan
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000000981:diagnostic imaging; D001003:Anal Canal / Q000002:abnormalities* / Q000473:pathology; D002988:Cloaca / Q000002:abnormalities* / Q000473:pathology; D000013:Congenital Abnormalities / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities* / Q000473:pathology; D007674:Kidney Diseases / Q000151:congenital* / Q000473:pathology; D008297:Male; D011247:Pregnancy; D059285:Pregnancy, Twin; D016216:Ultrasonography, Prenatal / Q000379:methods