title: Differences in Adherence and Non-Adherence Behaviour Patterns to Inhaler Devices Between COPD and Asthma Patients.
abstract: Differences between COPD and asthma may also differentially affect adherence to inhaled drugs in each disease. We aimed to determine differences in behaviour patterns of adherence and non-adherence to inhaled therapy between patients with COPD and patients with asthma using the Test of Adherence to Inhalers (TAI) questionnaire. A total of 910 patients (55% with asthma, 45% with COPD) participated in a cross-sectional multicentre study. Data recorded included sociodemographics, education level, asthma or COPD history, TAI score, the Asthma Control Test (ACT), the COPD Assessment Test (CAT) and spirometry. Asthma patients were statistically significant less adherents, 140 (28%) vs. 201 (49%), and the pattern of non-adherence was more frequently erratic (66.8% vs. 47.8%) and deliberate (47.2% vs. 34.1%) than COPD patients; however unwitting non-adherence was more frequently observed in COPD group (31.2% vs. 22.8%). Moreover, taking together all sample studied, only being younger than 50 years of age (OR 1.88 [95% CI: 1.26-2.81]) and active working status (OR 1.45 [95% CI: 1.00-2.09]) were risk factors for non-adherence in the multivariate analysis, while having asthma remained in the limits of the significance (OR 1.44 [95%CI: 0.97-2.14]). Even though non-adherence to inhalers is more frequently observed in asthma than in COPD patients and exhibited a different non-adherence patterns, these differences are more likely to be related to sociodemographic characteristics. However, differences in non-adherence patterns should be considered when designing specific education programmes tailored to each disease.
authors.affiliation: a Department of Respiratory Medicine, Hospital de la Santa Creu i Sant Pau , Institut d'Investigació Biomédica Sant Pau (IIB Sant Pau), Universitat Autònoma de Barcelona, Department of Medicine , Barcelona , Spain.
authors.forename: Vicente
authors.initials: V
authors.lastname: Plaza
authors.affiliation: b Pulmonology Department, Hospital Universitario Puerta de Hierro , Majadahonda , Madrid , Spain.
authors.forename: Antolín
authors.initials: A
authors.lastname: López-Viña
authors.affiliation: c Pulmonology Department, Hospital Reina Sofía , Córdoba , Spain.
authors.forename: Luis Manuel
authors.initials: LM
authors.lastname: Entrenas
authors.affiliation: d Facultad de Psicología, Universidad de Oviedo , Oviedo , Asturias , Spain.
authors.forename: Concepción
authors.initials: C
authors.lastname: Fernández-Rodríguez
authors.affiliation: e Pulmonology Department, Hospital Universitario 12 de Octubre, Institute for Health Research (i+12) , Madrid , Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Melero
authors.affiliation: f Pulmonology Department, Hospital Universitario Lucus Augusti , Lugo , Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Pérez-Llano
authors.affiliation: a Department of Respiratory Medicine, Hospital de la Santa Creu i Sant Pau , Institut d'Investigació Biomédica Sant Pau (IIB Sant Pau), Universitat Autònoma de Barcelona, Department of Medicine , Barcelona , Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Gutiérrez-Pereyra
authors.affiliation: g Medical Department, Chiesi Spain, L'Hospitalet de Llobregat , Barcelona , Spain.
authors.forename: Eduard
authors.initials: E
authors.lastname: Tarragona
authors.affiliation: h Área de investigación aplicada, GOC Networking , Barcelona , Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: Palomino
authors.affiliation: i Department of Respiratory Medicine , Hospital Son Espases, Palma de Mallorca. CIBER Enfermedades Respiratorias (CIBERES) , Spain.
authors.forename: Borja G
authors.initials: BG
authors.lastname: Cosio
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000188:drug therapy*; D003430:Cross-Sectional Studies; D004651:Employment; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy*; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014836:Volition; D055815:Young Adult; D016903:Drug Monitoring
keywords: COPD; inhalation technique; inhaled therapy; inhaler devices; medication adherence; medication non-adherence; test of adherence to inhalers