title: [A Case of Muscle Invasive Bladder Cancer in a Patient with Systemic Lupus Erythematosus].
abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease with various symptoms. We present a case of muscle invasive bladder cancer with lymph node swelling caused by SLE. A 60-year-old man was referred to our hospital with high fever and pollakisuria, micro hematuria, proteinuria. We detecteda papillary tumor located behind the left ureteral orifice. Magnetic resonance imaging showed invasion of the tumor to the fat around the bladder. Computed tomography (CT) showed the swelling of left common iliac lymph node and bilateral inguinal lymph nodes. According to cystoscopy, imaging examination and transurethral resection of bladder tumor, we diagnosed it as a bladder cancer (cT3aN3M1). In addition, a close inspection of proteinuria was performed, and SLE was diagnosed. We started steroid therapy under the influence of neutropenia and thrombopenia caused by SLE. The swelling of lymph nodes disappeared on the CT three months later. After the therapy with gemcitabine andcisplatin, radical cystectomy and cutaneous ureterostomy were performed. Pathological examination showed invasive urothelial carcinoma and no lymph node metastasis. He now shows no evidence of disease 18 months after the operation.
authors.affiliation: The Department of Urology, Matsusaka Central General Hospital.
authors.forename: Kota
authors.initials: K
authors.lastname: Iida
authors.affiliation: The Department of Urology, Matsusaka Central General Hospital.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tomioka
authors.affiliation: The Department of Urology, Matsusaka Central General Hospital.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Maruyama
authors.affiliation: The Department of Urology, Matsusaka Central General Hospital.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Otani
authors.affiliation: The Department of Urology, Nara Medical University.
authors.forename: Kiyohide
authors.initials: K
authors.lastname: Fujimoto
mesh_terms: D002277:Carcinoma / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000473:pathology* / Q000628:therapy