title: Antimicrobial Activity of Bacillus amyloliquefaciens ANT1 Toward Pathogenic Bacteria and Mold: Effects on Biofilm Formation.
abstract: The intensive use and misuse of antibiotics over the last decades have generated a strong selective pressure for the emergence of multi-resistant strains and nosocomial infections. Biofilm has been demonstrated as a key parameter in spreading infections, especially in hospitals and healthcare units. Therefore, the development of novel anti-biofilm drugs is actually of the upmost importance. Here, the antimicrobial and antibiofilm activities toward pathogenic microorganisms of a set of non-ribosomal synthesized peptides and polyketides isolated from Bacillus amyloliquefaciens ANT1 culture supernatant are presented.
authors.affiliation: Department of Sciences for the Environment, University Parthenope of Naples, Centro Direzionale Isola C4, 80143, Naples, Italy. r.nastro@uniparthenope.it.
authors.forename: Rosa Anna
authors.initials: RA
authors.lastname: Nastro
authors.affiliation: Centre d'Ingenierie des Proteines, Bacterial Physiology and Genetics, Allée de la chimie, Université de Liège, Bat. B6, 4000, Liège, Belgium.
authors.forename: Anthony
authors.initials: A
authors.lastname: Arguelles-Arias
authors.affiliation: Unité de Bio-Industrie, Gembloux Agro-Bio Tech, Université de Liège, Passage des Déportés, 5030, Gembloux, Belgium.
authors.forename: Marc
authors.initials: M
authors.lastname: Ongena
authors.affiliation: Department of Biology, University Federico II of Naples, Complesso Universitario di Monte Sant'Angelo, Via Cinthia 5, 80126, Naples, Italy.
authors.forename: Amelia
authors.initials: A
authors.lastname: Di Costanzo
authors.affiliation: Department of Chemical Sciences, University Federico II of Naples, Complesso Universitario di Monte Sant'Angelo, Ed.4, Via Cinthia 5, 80126, Naples, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Trifuoggi
authors.affiliation: Department of Biology, University Federico II of Naples, Complesso Universitario di Monte Sant'Angelo, Ed.7, Via Cinthia 5, 80126, Naples, Italy. marco.guida@unina.it.
authors.forename: Marco
authors.initials: M
authors.lastname: Guida
authors.affiliation: Unité de Biotechnologies et Bioprocédés, Université Libre de Bruxelles, Av F.-D. Roosevelt, 50, CP165/61, 1050, Brussels, Belgium. pfickers@ulb.ac.be.
authors.forename: Patrick
authors.initials: P
authors.lastname: Fickers
keywords: Antibiofilm activity; Bacillus amyloliquefaciens; NRPS; PKS