title: Abdominal Aortic Thrombosis in a Healthy Neonate.
abstract: Abdominal aortic thrombosis is a rare entity in neonates and has mostly been associated with umbilical artery or cardiac catheterization. We present a complicated case of an otherwise healthy neonate who developed thrombosis of abdominal aorta with renal failure. Therapy with intravenous heparin was unsuccessful, and thrombolysis was contraindicated because of disseminated intravascular coagulation so we decided to perform open thrombectomy using the left retroperitoneal approach. The following day, thrombosis recurred in the same extent and despite high risk of bleeding Alteplase was eventually given, which resulted in recanalization of the aorta 6 hours later. Renal function recovered, dialysis was discontinued, and further course was uneventful. The treatment of abdominal aortic thrombosis in neonates should be considered on a case-by-case basis because the available data on the condition are limited to case report and series. If open thrombectomy is performed, retroperitoneal approach should be preferred because it allows for easy institution of peritoneal dialysis should the need arise.
authors.affiliation: Department of Surgery, Clinical Hospital Center Zagreb, Zagreb, Croatia.
authors.forename: Marko
authors.initials: M
authors.lastname: Bogović
authors.affiliation: Department of Surgery, Clinical Hospital Center Zagreb, Zagreb, Croatia. Electronic address: dinopapes@gmail.com.
authors.forename: Dino
authors.initials: D
authors.lastname: Papeš
authors.affiliation: Department of Surgery, Clinical Hospital Center Zagreb, Zagreb, Croatia.
authors.forename: Davorin
authors.initials: D
authors.lastname: Mitar
authors.affiliation: Department of Radiology, Clinical Hospital Center Zagreb, Zagreb, Croatia.
authors.forename: Ranko
authors.initials: R
authors.lastname: Smiljanić
authors.affiliation: Department of Surgery, Clinical Hospital Center Zagreb, Zagreb, Croatia.
authors.forename: Suzana
authors.initials: S
authors.lastname: Sršen-Medančić
authors.affiliation: Department of Surgery, Clinical Hospital Center Zagreb, Zagreb, Croatia.
authors.forename: Stanko
authors.initials: S
authors.lastname: Ćavar
authors.affiliation: Department of Surgery, Clinical Hospital Center Zagreb, Zagreb, Croatia.
authors.forename: Anko
authors.initials: A
authors.lastname: Antabak
authors.affiliation: Department of Surgery, Clinical Hospital Center Zagreb, Zagreb, Croatia.
authors.forename: Tomislav
authors.initials: T
authors.lastname: Luetić
mesh_terms: D061605:Administration, Intravenous; D000925:Anticoagulants / Q000008:administration & dosage; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging; D001018:Aortic Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D001027:Aortography / Q000379:methods; D000072226:Computed Tomography Angiography; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010530:Peritoneal Dialysis; D012008:Recurrence; D051437:Renal Insufficiency / Q000175:diagnosis / Q000628:therapy; D017131:Thrombectomy; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006493:Heparin; D010959:Tissue Plasminogen Activator