title: Kikuchi-Fujimoto Disease: a Case Report.
abstract: Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is an idiopathic, self-limiting disorder and predominantly affects young women. We report a 35-year-old female who presented with soft to firm cervical lymphadenopathy and neck pain. She had multiple enlarged cervical nodes. Examination of other systems was normal. Lymph node biopsy was performed, and the histological features, and immunohistochemistry confirmed the diagnosis. The Patient was treated with non-steroidal anti-inflammatory drugs and low-dose prednisolone. A significant decrease in the size of lymph node and relief of neck pain occurred. During four years of follow-up, the patient developed no malignant disease or systemic and autoimmune diseases such as systemic lupus erythematosus. Kikuchi-Fujimoto disease is rare, clinicians should be aware of this condition as early diagnosis of the disease will lessen concerns of the patient's family.
authors.affiliation: Department of Internal Medicine, Taleghani Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
authors.forename: Mozaffar
authors.initials: M
authors.lastname: Aznab
authors.affiliation: Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Naser
authors.initials: N
authors.lastname: Kamalian
authors.affiliation: Department of Internal Medicine, Taleghani Hospital, Kermanshah, Iran.
authors.forename: Jaffar
authors.initials: J
authors.lastname: Navabi
authors.affiliation: Department of Paramedical, School of Medicine, Kermanshah of University Medical Sciences, Kermanshah, Iran.
authors.forename: Kaveh
authors.initials: K
authors.lastname: Kavianimoghadam
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001706:Biopsy; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008198:Lymph Nodes; D011239:Prednisolone / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D011239:Prednisolone
keywords: Histiocytic necrotizing lymphadenitis; Kikuchi-Fujimoto disease