title: [Fecal bacteriotherapy for the treatment of recurrent Clostridium difficile colitis used in the Clinic of Infectious Diseases of the University Hospital Brno in 2010-2014 - a prospective study].
abstract: BACKGROUND
  The aim of the study is to assess the efficacy of fecal bacteriotherapy in the treatment of Clostridium difficile colitis.
  
  
  METHODS
  A prospective study of fecal bacteriotherapy in 80 adult patients hospitalized in the Clinic of Infectious Diseases, University Hospital Brno between 1 January 2010 and 31 December 2014.
  
  
  RESULTS
  During the study period, 80 patients were treated with fecal bacteriotherapy. The majority of the study group received fecal bacteriotherapy via a nasojejunal tube (n=78) and two patients via a rectal enema. Six patients were instilled with 20 g of feces, with a success rate of 50 %. The outcomes of nine patients were unevaluable. In the rest of 65 patients, the success rate with 40 g of feces was 83.1 %. There were no severe adverse events or mortality associated with fecal bacteriotherapy.
  
  
  CONCLUSIONS
  Fecal bacteriotherapy is a safe and effective treatment modality in Clostridium difficile colitis.
authors.forename: P
authors.initials: P
authors.lastname: Polák
authors.forename: M
authors.initials: M
authors.lastname: Freibergerová
authors.forename: P
authors.initials: P
authors.lastname: Husa
authors.forename: J
authors.initials: J
authors.lastname: Juránková
authors.forename: R
authors.initials: R
authors.lastname: Svačinka
authors.forename: L
authors.initials: L
authors.lastname: Mikešová
authors.forename: H
authors.initials: H
authors.lastname: Kocourková
authors.forename: M
authors.initials: M
authors.lastname: Mihalčin
authors.forename: R
authors.initials: R
authors.lastname: Skalická
authors.forename: R
authors.initials: R
authors.lastname: Stebel
authors.forename: M
authors.initials: M
authors.lastname: Porubčanová
mesh_terms: D000328:Adult; D000554:Ambulatory Care Facilities; D001691:Biological Therapy; D016360:Clostridioides difficile / Q000502:physiology* / Q000821:virology*; D003015:Clostridium Infections / Q000382:microbiology / Q000628:therapy*; D003092:Colitis / Q000382:microbiology / Q000628:therapy*; D018153:Czech Republic; D005243:Feces / Q000382:microbiology*; D005260:Female; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome
keywords: Clostridium difficile colitis - recurrence - fecal bacteriotherapy.