title: [A Case of Spontaneous Regression of Breast Cancer with Multiple Lung Metastases].
abstract: Spontaneous regression of any malignant tumor is a rare event, occurring in about 1 of 60,000-100,000 cases of malignant tumor. We report a case of spontaneous regression of breast cancer with multiple pulmonary metastases. The patient was a 73-year-old woman who complained of a left mammary mass. A tumor, approximately 2.2 cm in diameter, was palpated, and breast cancer was suspected based on ultrasound examination. Histopathological findings of the core needle biopsy specimen indicated invasive ductal carcinoma. The patient underwent partial mastectomy with axillary lymph node dissection. It was a stage ⅡB (pT2N1 [sn] M0) tumor. CT performed after adjuvant therapy confirmed the presence of multiple pulmonary metastases 6 years after surgery. We started anti-cancer therapy with TS-1; however, it was discontinued because an adverse event occurred. Half a year later, tumor shrinkage was confirmed after a recurrence. Four years and 6 months after the treatment was discontinued, the tumor continued to regress spontaneously.
authors.affiliation: Dept. of Surgical Oncology, Osaka City University Graduate School of Medicine.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Asano
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Kashiwagi
authors.forename: Wataru
authors.initials: W
authors.lastname: Goto
authors.forename: Kento
authors.initials: K
authors.lastname: Kurata
authors.forename: Tamami
authors.initials: T
authors.lastname: Morisaki
authors.forename: Satoru
authors.initials: S
authors.lastname: Noda
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Takashima
authors.forename: Naoyoshi
authors.initials: N
authors.lastname: Onoda
authors.forename: Masahiko
authors.initials: M
authors.lastname: Ohsawa
authors.forename: Kosei
authors.initials: K
authors.lastname: Hirakawa
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D018270:Carcinoma, Ductal, Breast / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008197:Lymph Node Excision; D015412:Mastectomy, Segmental; D009365:Neoplasm Regression, Spontaneous; D017640:Silicates / Q000627:therapeutic use; D014025:Titanium / Q000627:therapeutic use
chemical_list: D017640:Silicates; C103828:titanium silicide; D014025:Titanium