title: [A Case of Idiopathic Thrombocytopenic Purpura during Adjuvant Chemotherapy for Colon Cancer].
abstract: A 76-year-old man underwent surgery for sigmoid colon cancer. The pathological finding was stage Ⅱ with a high-risk of recurrence (SI [bladder], l y0, v2, pN0, H0, P0, M0). He was treated with TS-1 as adjuvant chemotherapy. After the 1 course of chemotherapy, his platelet count was 4,000/mL. The high index of platelet associated IgG (PA-IgG) and bone marrow examination suggested that thrombocytopenia was caused by idiopathic thrombocytopenic purpura. The platelet count improved by prednisolone administration and Helicobacter pylori eradication treatment. After 6 months with no administration of adjuvant chemotherapy, the colon cancer recurred locally, and we performed a Hartmann's operation.
authors.affiliation: Dept. of Surgery, JCHO Funbashi Central Hospital.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Takahara
authors.forename: Shinichi
authors.initials: S
authors.lastname: Ozawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ogasawara
authors.forename: Takashi
authors.initials: T
authors.lastname: Shida
authors.forename: Satoru
authors.initials: S
authors.lastname: Nomura
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Sato
authors.forename: Makoto
authors.initials: M
authors.lastname: Takahashi
mesh_terms: D000368:Aged; D017024:Chemotherapy, Adjuvant; D016481:Helicobacter Infections / Q000628:therapy; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000139:chemically induced* / Q000188:drug therapy; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000601:surgery; D017640:Silicates / Q000009:adverse effects* / Q000627:therapeutic use; D014025:Titanium / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D017640:Silicates; C103828:titanium silicide; D014025:Titanium