title: [Analysis of the efficacy of gastric cancer screening in rural population in Henan Province].
abstract: OBJECTIVE
  To analyze the efficacy of endoscopic screening for gastric cancer in rural population in high risk areas of upper gastrointestinal cancer in Henan province.
  
  
  METHODS
  Subjects aged 40-69 years in the high risk areas were selected to participate in the endoscopic screening based on the cluster sampling, and screening-positive subjects were sampled for pathological examination. The data of screening were summarized and the detection rates of severe chronic atrophic gastritis, severe intestinal metaplasia, low grade intraepithelial neoplasia, high grade intraepithelial neoplasia, early and middle-late cancer were calculated, and the constituent ratio of early cancer cases was calculated. The detection rates and early diagnosis rates for the first round screening and follow-up screening were compared.
  
  
  RESULTS
  In the 5 years, a total of 88 263 subjects were endoscopically examined in the first round screening and 4 004 subjects were diagnosed with low grade intraepithelial neoplasia or above (the detection rate was 4.54%), in which 3 256 cases were with low grade intraepithelial neoplasia (the detection rate of 3.69%), 366 cases with high grade intraepithelial neoplasia (the rate of 0.41%), 199 cases with early cancer (the rate of 0.22%) and 183 cases with middle-late cancer (the rate of 0.21%). The number of cases of high grade intraepithelial neoplasia and early cancer was 565 and the early diagnosis rate was 75.53%. 1 894 subjects with severe chronic atrophic gastritis, severe intestinal metaplasia and low grade intraepithelial were followed up with a compliance of 66.32%. A total of 45 cases of early cancer were diagnosed, with a detection rate of 2.38% and early diagnosis rate of 100%. The detection rate and early diagnosis rate in the follow-up screening were both statistically significantly higher than that in the first round screening (P<0.01 for both).
  
  
  CONCLUSIONS
  The efficacy of endoscopic screening for gastric cancer is significant in high risk areas of upper gastrointestinal cancer, and improving the quality of follow-up screening will achieve a better performance of the screening.
authors.affiliation: Henan Cancer Hospital & Institute, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department o f Safety Engineering, Henan University of Engineering, Zhengzhou 451191, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.affiliation: Henan Cancer Hospital & Institute, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.
authors.forename: Shaokai
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Henan Cancer Hospital & Institute, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Henan Cancer Hospital & Institute, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.
authors.forename: Shuzheng
authors.initials: S
authors.lastname: Liu
authors.affiliation: Henan Cancer Hospital & Institute, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.
authors.forename: Lanwei
authors.initials: L
authors.lastname: Guo
authors.affiliation: Henan Cancer Hospital & Institute, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.
authors.forename: Jianbang
authors.initials: J
authors.lastname: Lu
authors.affiliation: Henan Cancer Hospital & Institute, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China.
authors.forename: Xibin
authors.initials: X
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D002278:Carcinoma in Situ / Q000175:diagnosis* / Q000473:pathology; D002681:China; D002908:Chronic Disease; D055088:Early Detection of Cancer / Q000706:statistics & numerical data*; D005757:Gastritis, Atrophic / Q000175:diagnosis; D005773:Gastroscopy; D006801:Humans; D008403:Mass Screening; D008875:Middle Aged; D012424:Rural Population; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology