title: Primary neuroendocrine tumour of the breast: a case report and review of the literature.
abstract: Primary neuroendocrine tumour of the breast is a rare entity that first appeared in the 2003 World Health Organisation (WHO) classification of breast tumours. The data currently available on its prognosis are contradictory, although it seems clear that histological varieties such as small cell neuroendocrine carcinoma have a worse prognosis, due to their low degree of differentiation. The treatment of choice is surgery, and the indications for chemotherapy or radiotherapy do not differ greatly from those used for other breast tumours. It is crucial to underline the difficulty of establishing treatment protocols due to the low incidence of this histological type.
authors.affiliation: Clinical Management Unit, Gynaecology and Obstetrics, Hospital Universitario Virgen Macarena, Sevilla 41008, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Tato-Varela
authors.affiliation: Clinical Management Unit, Gynaecology and Obstetrics, Hospital Universitario Virgen Macarena, Sevilla 41008, Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: Albalat-Fernández
authors.affiliation: Pathological Anatomy Service, Hospital Universitario Virgen Macarena, Sevilla 41008, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Pabón-Fernández
authors.affiliation: Pathological Anatomy Service, Hospital Universitario Virgen Macarena, Sevilla 41008, Spain.
authors.forename: Enrique Rodríguez
authors.initials: ER
authors.lastname: Zarco
authors.affiliation: Clinical Management Unit, Gynaecology and Obstetrics, Hospital Universitario Virgen Macarena, Sevilla 41008, Spain.
authors.forename: Manolo La
authors.initials: ML
authors.lastname: Calle-Marcos
keywords: breast; endocrine carcinoma; invasive carcinoma; neuroendocrine carcinoma