title: Ionic liquid supported organotin reagents to prepare molecular imaging and therapy agents.
abstract: Efficiency of ionic liquid supported organotin reagents in halodemetalation reaction has been investigated. High radiochemical yields of astatinated and iodinated compounds have been obtained using simple work-up procedure. This methodology represents a straightforward approach for the preparation of molecular imaging and therapy agents in nuclear medicine.
authors.affiliation: Université de Nantes, CRCNA, UMR 892 INSERM-6299 CNRS, 8 Quai Moncousu, 44000 Nantes, France. holisoa.rajerison@univ-nantes.fr jfgestin@nantes.inserm.fr.
authors.forename: Holisoa
authors.initials: H
authors.lastname: Rajerison
authors.affiliation: Université d'Angers, Laboratoire MOLTECH-Anjou, CNRS UMR 6200, 2 Boulevard Lavoisier, F-49045 Angers, France. stephanie.legoupy@univ-angers.fr.
authors.forename: Djibril
authors.initials: D
authors.lastname: Faye
authors.affiliation: Université de Nantes, CRCNA, UMR 892 INSERM-6299 CNRS, 8 Quai Moncousu, 44000 Nantes, France. holisoa.rajerison@univ-nantes.fr jfgestin@nantes.inserm.fr.
authors.forename: Aurélia
authors.initials: A
authors.lastname: Roumesy
authors.affiliation: LUNAM Université, Université du Maine, CNRS UMR 6283, Institut des Molécules et Matériaux du Mans (IMMM), 72085 Le Mans Cedex 09, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Louaisil
authors.affiliation: LUNAM Université, Université du Maine, CNRS UMR 6283, Institut des Molécules et Matériaux du Mans (IMMM), 72085 Le Mans Cedex 09, France.
authors.forename: Fabien
authors.initials: F
authors.lastname: Boeda
authors.affiliation: Université de Nantes, CRCNA, UMR 892 INSERM-6299 CNRS, 8 Quai Moncousu, 44000 Nantes, France. holisoa.rajerison@univ-nantes.fr jfgestin@nantes.inserm.fr.
authors.forename: Alain
authors.initials: A
authors.lastname: Faivre-Chauvet
authors.affiliation: Université de Nantes, CRCNA, UMR 892 INSERM-6299 CNRS, 8 Quai Moncousu, 44000 Nantes, France. holisoa.rajerison@univ-nantes.fr jfgestin@nantes.inserm.fr.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Gestin
authors.affiliation: Université d'Angers, Laboratoire MOLTECH-Anjou, CNRS UMR 6200, 2 Boulevard Lavoisier, F-49045 Angers, France. stephanie.legoupy@univ-angers.fr.
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Legoupy
mesh_terms: D007457:Iodine Radioisotopes / Q000737:chemistry / Q000627:therapeutic use; D052578:Ionic Liquids / Q000737:chemistry*; D057054:Molecular Imaging / Q000379:methods*; D015394:Molecular Structure; D009683:Nuclear Medicine; D009947:Organotin Compounds / Q000737:chemistry*; D011863:Radioimmunoassay; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D007457:Iodine Radioisotopes; D052578:Ionic Liquids; D009947:Organotin Compounds; D019275:Radiopharmaceuticals