title: Diagnosis of an additional in situ melanoma does not influence survival for patients with a single invasive melanoma: A registry-based follow-up study.
abstract: Using a large (N= 25 493) population-based cohort from Queensland, Australia, we compared melanoma survival among cases with a single invasive melanoma only against those who also had a diagnosis of a single in situ melanoma. After adjustment for sex, age, body site, clinicopathological subtype, thickness and ulceration, it was found that there was no difference (P = 0.99) in 10-year melanoma-specific mortality following a diagnosis of an invasive lesion, whether or not an in situ melanoma was also present. We conclude that in situ melanomas do not alter the prognosis of an invasive melanoma.
authors.affiliation: Cancer Council Queensland, Brisbane, Queensland, Australia.
authors.forename: Danny R
authors.initials: DR
authors.lastname: Youlden
authors.affiliation: University of Queensland Centre for Clinical Research, Brisbane, Queensland, Australia.
authors.forename: Kiarash
authors.initials: K
authors.lastname: Khosrotehrani
authors.affiliation: QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.|CRUK Manchester Institute, University of Manchester, Manchester, UK.
authors.forename: Adèle C
authors.initials: AC
authors.lastname: Green
authors.affiliation: Dermatology Research Centre, School of Medicine, Translational Research Institute, University of Queensland, Brisbane, Queensland, Australia.
authors.forename: H Peter
authors.initials: HP
authors.lastname: Soyer
authors.affiliation: University of the Sunshine Coast, Sunshine Coast, Queensland, Australia.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Kimlin
authors.affiliation: Cancer Council Queensland, Brisbane, Queensland, Australia.
authors.forename: Philippa H
authors.initials: PH
authors.lastname: Youl
authors.affiliation: Cancer Council Queensland, Brisbane, Queensland, Australia.
authors.forename: Joanne F
authors.initials: JF
authors.lastname: Aitken
authors.affiliation: Cancer Council Queensland, Brisbane, Queensland, Australia.
authors.forename: Peter D
authors.initials: PD
authors.lastname: Baade
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000401:mortality* / Q000473:pathology*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D016609:Neoplasms, Second Primary / Q000401:mortality* / Q000473:pathology*; D011793:Queensland / Q000453:epidemiology; D012042:Registries; D012878:Skin Neoplasms / Q000401:mortality* / Q000473:pathology*; D015996:Survival Rate; D055815:Young Adult
keywords: in situ; invasive; melanoma; survival