title: Hemodynamic study of the elliptic St. Jude Medical valve: A computational study.
abstract: Despite successful implantation of St. Jude Medical bileaflet mechanical heart valves, red blood cell lysis and thrombogenic complications associated with these types of valves are yet to be addressed. In our previous study, we proposed an elliptic housing where 10% ovality was applied to the housing of St. Jude Medical valves. Our preliminary results suggested that the overall hemodynamic performance of St. Jude Medical valves improved in both the closing and opening phases. In this study, we evaluated the hemodynamics around the leaflets in the opening phase using a more sophisticated computational platform, computational fluid dynamics. Results suggested both lower shear stress and wall shear stress values and an overall improved hemodynamic performance in the proposed design. This improvement is characterized by lower values of shear stress and wall shear stress in the regions downstream of the leaflets, lower pressure drop across the valve and smaller recirculation zones in the sinuses areas. The proposed design may open a new chapter in the concept of design and hemodynamic improvement of the next generation of mechanical heart valves.
authors.affiliation: The Heart Valve Performance Laboratory, School of Engineering, Faculty of Applied Science, The University of British Columbia, Okanagan Campus, Kelowna, BC, Canada.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Jahandardoost
authors.affiliation: The Heart Valve Performance Laboratory, School of Engineering, Faculty of Applied Science, The University of British Columbia, Okanagan Campus, Kelowna, BC, Canada Department of Surgery, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
authors.forename: Guy
authors.initials: G
authors.lastname: Fradet
authors.affiliation: The Heart Valve Performance Laboratory, School of Engineering, Faculty of Applied Science, The University of British Columbia, Okanagan Campus, Kelowna, BC, Canada Department of Surgery, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada Biomedical Engineering Graduate Program, Faculty of Applied Science, The University of British Columbia, Vancouver, BC, Canada hadi.mohammadi@ubc.ca.
authors.forename: Hadi
authors.initials: H
authors.lastname: Mohammadi
mesh_terms: D001696:Biomechanical Phenomena; D006350:Heart Valve Prosthesis; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D011474:Prosthesis Design; D013314:Stress, Mechanical
keywords: Computational fluid dynamics; St. Jude Medical valve; bileaflet mechanical heart valve; cardiovascular fluid mechanics; shear stress transport turbulence modeling