title: Completion thyroidectomy and total thyroidectomy for differentiated thyroid cancer: Comparison and prediction of postoperative hypoparathyroidism.
abstract: BACKGROUND
  Consensus regarding the difference of postoperative hypoparathyroidism following completion thyroidectomy (CT) and total thyroidectomy (TT) has yet to be reached. We compare the occurrence of postoperative hypoparathyroidism between CT and TT for differentiated thyroid cancer (DTC), and explore the predictive factors for postoperative hypoparathyroidism.
  
  
  METHODS
  We retrospectively reviewed 221 consecutive patients underwent CT or TT for DTC between February 2012 and March 2014. Patients' demographic and clinical data of the two groups were analyzed.
  
  
  RESULTS
  There were 57 CTs and 164 TTs. Temporary hypoparathyroidism occurred in 12.3% (7 of 57) and 28.0% (46 of 164) of patients in the CT and TT groups, respectively. In univariate analysis, type of surgical procedure (CT or TT) and extent of central lymph node dissection (CND) (unilateral or bilateral) were significantly associated with the postoperative temporary hypoparathyroidism (P < 0.05). Multivariate analysis showed that only the extent of CND was an independent risk factor for temporary hypoparathyroidism.
  
  
  CONCLUSIONS
  Although temporary hypoparathyroidism was lower in the CT group, our analysis indicates the difference is due to the extent of CND rather than type of surgical procedure (CT vs. TT). Only bilateral CND is an independent risk factor for temporary hypoparathyroidism after thyroidectomy. J. Surg. Oncol. 2016;113:522-525. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, Chendu, China.|Department of General Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, Chendu, China.
authors.forename: Tengfei
authors.initials: T
authors.lastname: Xing
authors.affiliation: Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, Chendu, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wei
authors.affiliation: Department of Thyroid and Breast Surgery, West China Hospital, Sichuan University, Chendu, China.
authors.forename: Jingqiang
authors.initials: J
authors.lastname: Zhu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007011:Hypoparathyroidism / Q000453:epidemiology*; D015994:Incidence; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D013964:Thyroid Neoplasms / Q000601:surgery*; D013965:Thyroidectomy
keywords: completion thyroidectomy; differentiated thyroid cancer; hypoparathyroidism; total thyroidectomy