title: Multidetector computed tomography in the evaluation of hereditary multiple exostoses.
abstract: Hereditary multiple exostoses (HME) is an autosomal dominant disorder characterized by the formation of multiple osteochondromas. Because of its superior soft tissue contrast and absence of ionizing radiation, magnetic resonance imaging is the first choice imaging technique for the evaluation of complex lesions and complications related to HME. However, multidetector computed tomography (MDCT) also can be of value in the evaluation of patients with HME, which is reviewed in this article. Topics outlined are low-dose MDCT technique, 3-dimensional visualization techniques, typical MDCT appearances, differential diagnostic considerations, and the usefulness of MDCT in the assessment of emergent and non-emergent complications related to HME, among which spinal cord compression, pneumothorax and hematothorax, pseudoaneurysms, fractures, growth disturbances, chondrosarcoma transformation, and muscular and peripheral nerve involvement.
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Radiology, Zuyderland Medical Center, Heerlen, The Netherlands.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Kwee
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
authors.forename: Laura M
authors.initials: LM
authors.lastname: Fayad
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
authors.forename: Elliot K
authors.initials: EK
authors.lastname: Fishman
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States. Electronic address: jfritz9@jhmi.edu.
authors.forename: Jan
authors.initials: J
authors.lastname: Fritz
mesh_terms: D005097:Exostoses, Multiple Hereditary / Q000000981:diagnostic imaging*; D006801:Humans; D061330:Multidetector Computed Tomography / Q000379:methods*; D013117:Spinal Cord Compression / Q000000981:diagnostic imaging
keywords: CT; Computed tomography; HME; Hereditary multiple exostoses; MDCT; Multidetector; Osteochondroma