title: Chasing One-Carbon Units to Understand the Role of Serine in Epigenetics.
abstract: In this issue of Molecular Cell, Maddocks et al. (2016) use stable isotope tracing, mass spectrometry, and nutrient modulation in cancer cells to highlight the role of serine in supporting methylation through maintenance of nucleotide levels.
authors.affiliation: Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
authors.forename: Seth J
authors.initials: SJ
authors.lastname: Parker
authors.affiliation: Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Moores Cancer Center, University of California, San Diego, La Jolla, California 92093, USA. Electronic address: cmetallo@eng.ucsd.edu.
authors.forename: Christian M
authors.initials: CM
authors.lastname: Metallo
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis*; D019175:DNA Methylation; D006801:Humans; D008715:Methionine / Q000378:metabolism*; D009369:Neoplasms / Q000378:metabolism*; D012694:Serine / Q000378:metabolism*
chemical_list: D012694:Serine; D000255:Adenosine Triphosphate; D008715:Methionine