title: [Basaloid Carcinoma of the Esophagus with Lugol-Voiding Lesions--A Case Report].
abstract: Patients with Lugol-voiding lesions of the esophagus are frequently affected with multiple cancers. Basaloid carcinoma of the esophagus is a very rare disease characterized by growth in the submucosal layer that exhibits a submucosal tumor-like shape. There have been some reports that this type of carcinoma is biologically high-grade. We report a case of metachronous squamous cell carcinoma in situ and superficial basaloid carcinoma in the esophagus with Lugol-voiding lesions. A 63-year-old man underwent gastrectomy for gastric cancer at the age of 45 years. The subsequent surveillance endoscopy found a type 0-Ⅱc lesion in the esophagus in 2000. EMR was thus performed. The pathology showed squamous cell carcinoma in situ. Dysplasia was diagnosed based on the Lugol-voiding lesions, and EMR was performed twice. In 2014, a fourth EMR was performed after a high-grade intraepithelial neoplasia was diagnosed. The pathology showed squamous cell carcinoma in situ and a basaloid carcinoma in the lamina propria, T1a-LPM, ly0, v0, pHMX, pVM0. The patient has had no recurrence for approximately 1 year after the fourth EMR.
authors.affiliation: Dept. of Surgery, Tokyo Women's Medical University Medical Center East.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shimakawa
authors.forename: Shinichi
authors.initials: S
authors.lastname: Asaka
authors.forename: Asako
authors.initials: A
authors.lastname: Shimazaki
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Takebumi
authors.initials: T
authors.lastname: Usui
authors.forename: Hajime
authors.initials: H
authors.lastname: Yokomizo
authors.forename: Shunichi
authors.initials: S
authors.lastname: Shiozawa
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Yoshimatsu
authors.forename: Takao
authors.initials: T
authors.lastname: Katsube
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Naritaka
authors.forename: Mariko
authors.initials: M
authors.lastname: Fujibayashi
mesh_terms: D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D000077277:Esophageal Squamous Cell Carcinoma; D004945:Esophagoscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading