title: Considering Pre-Exposure Prophylaxis: Do the Pros Outweigh the Cons as an HIV Prevention Strategy?
abstract: Although increased access to antiretroviral therapy reduces the risk of sexual transmission to partners, ongoing HIV incidence can be sustained by people who are unaware of their infection. Thus, new prevention interventions that are designed for HIV-negative people at high risk of infection are important in the control of new HIV infections. Pre-Exposure Prophylaxis (PrEP) has proven efficacy in four major trials, but questions about its cost, about user adherence and about its potential impact on other prevention interventions such as condom use has limited implementation to date. This article examines the evidence.
authors.affiliation: 1 Kirby Institute, University of New South Wales , Sydney, Australia .|2 Centre for Values, Ethics and the Law in Medicine, Sydney University , Australia .
authors.forename: Bridget
authors.initials: B
authors.lastname: Haire
keywords: HIV prevention; PrEP; ethics; pre-exposure prophylaxis