title: Evidence-Based Pharmacologic Approaches for Chronic Orofacial Pain.
abstract: For neuropathic pain, the three medications to use are gabapentinoids, tricyclic antidepressants and serotonin norepinephrine reuptake inhibitors plus topical anesthetics. Beta-blockers, tricyclic antidepressants and anti-epileptic drugs are effective preventive medications for daily migraine headaches. The three FDA-approved drugs for fibromyalgia, pregabalin, duloxetine and milnacipran, are not robust. For osteoarthritis, nonsteroidal anti-inflammatories have good efficacy, and when gastritis contraindicates them, corticosteroid injections are helpful.
authors.forename: Glenn
authors.initials: G
authors.lastname: Clark
mesh_terms: D001168:Arthritis / Q000188:drug therapy; D059350:Chronic Pain / Q000188:drug therapy*; D055094:Evidence-Based Dentistry; D005157:Facial Pain / Q000188:drug therapy*; D005356:Fibromyalgia / Q000188:drug therapy; D020773:Headache Disorders / Q000188:drug therapy; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy; D009437:Neuralgia / Q000188:drug therapy